BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (237 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q46843 Uncharacterized ATP-binding protein yghS n=43 Ta...   491   e-138
UniRef50_P64573 Uncharacterized ATP-binding protein yghR n=42 Ta...   186   4e-46
UniRef50_C8WFA2 Putative uncharacterized protein n=3 Tax=Zymomon...   165   1e-39
UniRef50_Q5NMW8 Conserved predicted protein with nucleoside trip...   163   4e-39
UniRef50_Q46844 Uncharacterized ATP-binding protein yghT n=39 Ta...   159   6e-38
UniRef50_D2A7H7 Putative ATP-binding protein yghT n=3 Tax=Entero...   107   3e-22
UniRef50_Q2LPR0 Hypothetical cytosolic protein n=1 Tax=Syntrophu...    52   2e-05

>UniRef50_Q46843 Uncharacterized ATP-binding protein yghS n=43
           Tax=Enterobacteriaceae RepID=YGHS_ECOLI
          Length = 237

 Score =  491 bits (1264), Expect = e-138,   Method: Compositional matrix adjust.
 Identities = 237/237 (100%), Positives = 237/237 (100%)

Query: 1   MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWI 60
           MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWI
Sbjct: 1   MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWI 60

Query: 61  SQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFL 120
           SQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFL
Sbjct: 61  SQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFL 120

Query: 121 LITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDE 180
           LITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDE
Sbjct: 121 LITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDE 180

Query: 181 QTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
           QTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS
Sbjct: 181 QTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237


>UniRef50_P64573 Uncharacterized ATP-binding protein yghR n=42
           Tax=Enterobacteriaceae RepID=YGHR_ECOL6
          Length = 252

 Score =  186 bits (473), Expect = 4e-46,   Method: Compositional matrix adjust.
 Identities = 97/218 (44%), Positives = 134/218 (61%), Gaps = 2/218 (0%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA+VGCDG+GKSTLT  LV  L     TE  YLG  SG  G+ I +LP++G    R L 
Sbjct: 23  LIAVVGCDGTGKSTLTTDLVKSLQQHWQTERRYLGLLSGEDGDKIKRLPLVGVWLERRLA 82

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           +K++      +  P    A+++Y  S  R    RK+   +Q G L+++DR+PQ E+ GF 
Sbjct: 83  AKSSKTQSMKTKSPALWAAVIMYCFSLRRMANLRKVQRLAQSGVLVVSDRFPQAEISGFY 142

Query: 136 FDGPQLAKTTGGNGWIKM-LRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
           +DGP +       G I M L QRE +LYQ MA Y P L+IRLGID +TA +RKPDH  A 
Sbjct: 143 YDGPGIG-VERATGKISMFLAQRERRLYQQMAQYRPELIIRLGIDIETAISRKPDHDYAE 201

Query: 195 LQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAI 232
           LQ+KI V  ++ +NG KILE+D R P  E+L+ + +A+
Sbjct: 202 LQDKIGVMSKIGYNGTKILEIDSRAPYSEVLEQAQKAV 239


>UniRef50_C8WFA2 Putative uncharacterized protein n=3 Tax=Zymomonas mobilis
           RepID=C8WFA2_ZYMMN
          Length = 256

 Score =  165 bits (418), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 89/223 (39%), Positives = 128/223 (57%), Gaps = 1/223 (0%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           ++IA+VGCDGSGKS+LT  L+  +    P +  YLG  SG +G  I Q+PV+G+     L
Sbjct: 27  KLIALVGCDGSGKSSLTTDLIAAIQKYTPVKRYYLGLGSGDLGRKIGQIPVVGSWIENLL 86

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           + +A     K    PG +TALV+Y  S  R   + KM    + G  +ITDRYPQ E+ G 
Sbjct: 87  KQRATTTRTKGKKIPGVMTALVVYFFSLRRFCSYLKMRRALKAGITVITDRYPQAEIAG- 145

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
           + DGP L+    GN ++  L + E  LYQ MAS+ P L++RL +D +TA ARKPDH + A
Sbjct: 146 QCDGPGLSAAKAGNRFVSWLVRSEAALYQRMASFQPDLVLRLDVDPETAHARKPDHDIEA 205

Query: 195 LQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
           L+ K  +   LTF GA +  +D   P   + +  +R +   L+
Sbjct: 206 LRIKSEIMQHLTFGGAHMEVIDATRPYKAVWKDIVRLVQPYLT 248


>UniRef50_Q5NMW8 Conserved predicted protein with nucleoside triphosphate hydrolase
           domain n=3 Tax=Zymomonas mobilis RepID=Q5NMW8_ZYMMO
          Length = 240

 Score =  163 bits (413), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 84/217 (38%), Positives = 131/217 (60%), Gaps = 3/217 (1%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA+VG DGSGK+T+   L+  L    PT   +LG+ +G  G  I+++P +G    + + 
Sbjct: 14  LIALVGADGSGKTTVGQELLEWLQTMRPTAFCHLGKQTGNWGRAIARMPFVGRKLDKQVI 73

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           ++++   ++     G   ++VI+ LS  R ++F +M    ++GF+++TDRYPQ  VPG  
Sbjct: 74  ARSSKARDEKGA--GATVSIVIFALSMRRVFRFLRMRRLHRKGFMILTDRYPQAVVPG-P 130

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
            DGP L          + L  RE  LY WMASY P ++IRL +D +TA  RKPDH+ A+L
Sbjct: 131 MDGPGLVARNPKGMIARFLTGREQALYDWMASYKPDIVIRLNVDLETALKRKPDHRPASL 190

Query: 196 QEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAI 232
           + K+   P+L+FNGA IL+LD R P D+++  +  AI
Sbjct: 191 ERKVRDVPRLSFNGAPILDLDSREPLDQVIGKAKAAI 227


>UniRef50_Q46844 Uncharacterized ATP-binding protein yghT n=39
           Tax=Enterobacteriaceae RepID=YGHT_ECOLI
          Length = 230

 Score =  159 bits (403), Expect = 6e-38,   Method: Compositional matrix adjust.
 Identities = 79/217 (36%), Positives = 130/217 (59%), Gaps = 4/217 (1%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA++G DGSGKST+   L+  +      E ++LG+ +G +G  +++LP++G    + + 
Sbjct: 8   LIAVIGSDGSGKSTVCEHLITVVEKYGAAERVHLGKQAGNVGRAVTKLPLMGKSLHKTIE 67

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                  +K    PG + ALVI      R  +FR ML   ++G +++TDRYPQ ++PG  
Sbjct: 68  RNQVKTAKKL---PGPVPALVITAFVARRLLRFRHMLACRRRGLIVLTDRYPQDQIPGA- 123

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
           +DG        G  ++  L  +E K + WMAS+ P L+I+L +D + A ARKPDH+  +L
Sbjct: 124 YDGTVFPPNVEGGRFVSWLASQERKAFHWMASHKPDLVIKLNVDLEVACARKPDHKRESL 183

Query: 196 QEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAI 232
             KIA+TPQLTF GA+++++D   P +++L  + +AI
Sbjct: 184 ARKIAITPQLTFGGAQLVDIDANQPLEQVLVDAEKAI 220


>UniRef50_D2A7H7 Putative ATP-binding protein yghT n=3 Tax=Enterobacteriaceae
           RepID=D2A7H7_SHIF2
          Length = 131

 Score =  107 bits (267), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 50/122 (40%), Positives = 80/122 (65%), Gaps = 1/122 (0%)

Query: 111 MLCKSQQGFLLITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLP 170
           ML   ++G +++TDRYPQ ++PG  +DG        G  ++  L  +E K + WMAS+ P
Sbjct: 1   MLACRRRGLIVLTDRYPQDQIPG-AYDGTVFPPNVEGGRFVSWLASQERKAFHWMASHKP 59

Query: 171 VLLIRLGIDEQTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLR 230
            L+I+L +D + A ARKPDH+  +L  KIA+TPQLTF GA+++++D   P +++L  + +
Sbjct: 60  DLVIKLNVDLEVACARKPDHKRESLARKIAITPQLTFGGAQLVDIDANQPLEQVLVDAEK 119

Query: 231 AI 232
           AI
Sbjct: 120 AI 121


>UniRef50_Q2LPR0 Hypothetical cytosolic protein n=1 Tax=Syntrophus aciditrophicus SB
           RepID=Q2LPR0_SYNAS
          Length = 487

 Score = 51.6 bits (122), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 54/215 (25%), Positives = 96/215 (44%), Gaps = 11/215 (5%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQ-SSGRIGEWISQLPVIGAPFGRYL 74
           +IAIVG DG+GK+T+   +   L  +     +++G+ +  R     S    IG   G Y 
Sbjct: 268 LIAIVGGDGAGKTTVIEEVHKWLGRKFDVMKLHMGKPARSRTTILGSGFLKIGTMLGLY- 326

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
               A ++ + +  PG    + +  L+  R   + K    +  G L+I DRY   ++   
Sbjct: 327 -PATADLYAEEAEFPGYPFLIRMVFLAYDRYLTYLKARRFASNGGLVICDRYFLADL--L 383

Query: 135 RFDGPQ---LAKTTG-GNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH 190
             DGP+   +AK     N ++  L + E   Y+ M S  P LLI L ++ + A  RK D 
Sbjct: 384 TMDGPRCKMMAKAFNRSNFFMNWLIRIEASCYEKMMS--PDLLIVLRLNPEIAVQRKTDE 441

Query: 191 QLAALQEKIAVTPQLTFNGAKILELDGRHPADEIL 225
              +++ +     +  ++      +D   P +E+L
Sbjct: 442 TAVSVRARSTSIWEYDWSKTSACVVDSSRPKEEVL 476


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q46843 Uncharacterized ATP-binding protein yghS n=43 Ta...   352   5e-96
UniRef50_C8WFA2 Putative uncharacterized protein n=3 Tax=Zymomon...   312   4e-84
UniRef50_Q46844 Uncharacterized ATP-binding protein yghT n=39 Ta...   302   1e-80
UniRef50_P64573 Uncharacterized ATP-binding protein yghR n=42 Ta...   293   3e-78
UniRef50_Q5NMW8 Conserved predicted protein with nucleoside trip...   285   9e-76
UniRef50_Q2LPR0 Hypothetical cytosolic protein n=1 Tax=Syntrophu...   253   3e-66
UniRef50_D2A7H7 Putative ATP-binding protein yghT n=3 Tax=Entero...   191   2e-47

Sequences not found previously or not previously below threshold:

UniRef50_D2RGJ1 Thymidylate kinase n=2 Tax=Archaeoglobaceae RepI...    65   2e-09
UniRef50_C5KB73 Thymidylate kinase, putative n=2 Tax=Perkinsus m...    63   6e-09
UniRef50_Q1J3J7 Thymidylate kinase-like protein n=1 Tax=Deinococ...    62   1e-08
UniRef50_Q8SS22 THYMIDYLATE KINASE n=1 Tax=Encephalitozoon cunic...    58   3e-07
UniRef50_B8D357 Thymidylate kinase n=1 Tax=Desulfurococcus kamch...    58   3e-07
UniRef50_A1RTS9 Thymidylate kinase n=3 Tax=Thermoproteaceae RepI...    56   1e-06
UniRef50_O30175 Probable thymidylate kinase n=1 Tax=Archaeoglobu...    55   1e-06
UniRef50_B5IF40 Thymidylate kinase n=2 Tax=Aciduliprofundum boon...    54   3e-06
UniRef50_Q17LP5 Thymidylate kinase, putative n=4 Tax=Culicidae R...    53   7e-06
UniRef50_Q1NTS0 Putative uncharacterized protein n=1 Tax=delta p...    53   8e-06
UniRef50_Q67JB0 Thymidylate kinase n=1 Tax=Symbiobacterium therm...    53   8e-06
UniRef50_Q3B752 Zgc:123174 n=5 Tax=root RepID=Q3B752_DANRE             53   8e-06
UniRef50_Q1NU71 Putative uncharacterized protein n=1 Tax=delta p...    53   1e-05
UniRef50_B4CTS9 Putative uncharacterized protein n=1 Tax=Chthoni...    52   1e-05
UniRef50_P36590 Thymidylate kinase n=2 Tax=Ascomycota RepID=KTHY...    52   1e-05
UniRef50_B1V9T6 Thymidylate kinase n=9 Tax=16SrXII (Stolbur grou...    52   1e-05
UniRef50_UPI0001C375B1 putative thymidylate kinase n=1 Tax=Rumin...    52   1e-05
UniRef50_A3CPJ9 Thymidylate kinase n=29 Tax=Firmicutes RepID=KTH...    52   2e-05
UniRef50_A5N3T4 Tmk n=32 Tax=Bacteria RepID=A5N3T4_CLOK5               52   2e-05
UniRef50_C4DQR2 Thymidylate kinase n=1 Tax=Stackebrandtia nassau...    52   2e-05
UniRef50_Q5ZVP1 Thymidylate kinase n=5 Tax=Legionella RepID=KTHY...    51   4e-05
UniRef50_C0EEB4 Putative uncharacterized protein n=1 Tax=Clostri...    50   4e-05
UniRef50_A8Q2K3 Putative uncharacterized protein n=1 Tax=Malasse...    50   5e-05
UniRef50_Q9HLZ2 Probable thymidylate kinase n=2 Tax=Thermoplasma...    50   6e-05
UniRef50_C1BRK2 Thymidylate kinase n=1 Tax=Caligus rogercresseyi...    50   6e-05
UniRef50_Q0A8S2 Thymidylate kinase n=16 Tax=Gammaproteobacteria ...    50   6e-05
UniRef50_Q6L016 Probable thymidylate kinase n=1 Tax=Picrophilus ...    49   9e-05
UniRef50_Q0WW55 Thymidylate kinase-like protein n=22 Tax=Eukaryo...    49   1e-04
UniRef50_A3V698 Glycosyltransferase, group 1 n=1 Tax=Loktanella ...    49   1e-04
UniRef50_D2E8C8 ORF77 n=1 Tax=Anguillid herpesvirus 1 RepID=D2E8...    49   1e-04
UniRef50_A1VCE6 Thymidylate kinase n=15 Tax=Bacteria RepID=KTHY_...    49   1e-04
UniRef50_A9ETA2 Putative Thymidylate kinase n=1 Tax=Sorangium ce...    49   1e-04
UniRef50_Q0C176 Thymidylate kinase n=1 Tax=Hyphomonas neptunium ...    49   1e-04
UniRef50_B3T390 Putative Thymidylate kinase n=1 Tax=uncultured m...    49   2e-04
UniRef50_Q28SW8 Thymidylate kinase n=39 Tax=Rhodobacterales RepI...    49   2e-04
UniRef50_C7DHA0 dTMP kinase n=1 Tax=Candidatus Micrarchaeum acid...    49   2e-04
UniRef50_A7VTJ2 Putative uncharacterized protein n=2 Tax=Clostri...    49   2e-04
UniRef50_Q581B1 Thymidylate kinase, putative n=3 Tax=Trypanosoma...    48   2e-04
UniRef50_A6NRP2 Putative uncharacterized protein n=2 Tax=Bacteri...    48   2e-04
UniRef50_Q22018 Probable thymidylate kinase n=3 Tax=Caenorhabdit...    48   3e-04
UniRef50_C4KZW9 Thymidylate kinase n=1 Tax=Exiguobacterium sp. A...    48   3e-04
UniRef50_B5YD95 Thymidylate kinase n=1 Tax=Dictyoglomus thermoph...    48   3e-04
UniRef50_A6LPM3 Thymidylate kinase n=175 Tax=Firmicutes RepID=KT...    48   3e-04
UniRef50_B0EQM5 Thymidylate kinase, putative n=2 Tax=Entamoeba R...    48   3e-04
UniRef50_A2QUJ3 Catalytic activity: ATP + thymidine 5'-phosphate...    48   3e-04
UniRef50_C3ZEC2 Putative uncharacterized protein n=1 Tax=Branchi...    47   4e-04
UniRef50_A3DM71 Probable thymidylate kinase n=1 Tax=Staphylother...    47   4e-04
UniRef50_A9BCY7 Thymidylate kinase n=9 Tax=Prochlorococcus marin...    47   4e-04
UniRef50_D1PL57 dTMP kinase n=1 Tax=Subdoligranulum variabile DS...    47   4e-04
UniRef50_A6S4P1 Putative uncharacterized protein n=2 Tax=Sclerot...    47   4e-04
UniRef50_C6A0S1 Probable thymidylate kinase n=4 Tax=Thermococcus...    47   4e-04
UniRef50_Q601T1 Thymidylate kinase n=6 Tax=Mycoplasma RepID=KTHY...    47   5e-04
UniRef50_A5G4M6 Thymidylate synthase / thymidylate kinase n=3 Ta...    47   5e-04
UniRef50_C6TJ88 Putative uncharacterized protein n=1 Tax=Glycine...    47   5e-04
UniRef50_D1YVU8 Probable thymidylate kinase n=2 Tax=Euryarchaeot...    47   5e-04
UniRef50_B6QFH6 Thymidylate kinase n=13 Tax=Eurotiomycetidae Rep...    47   6e-04
UniRef50_Q46DH6 Probable thymidylate kinase n=4 Tax=Methanosarci...    47   7e-04
UniRef50_A9DXA8 Thymidylate kinase n=1 Tax=Kordia algicida OT-1 ...    47   7e-04
UniRef50_A9A2S6 Thymidylate kinase n=1 Tax=Nitrosopumilus mariti...    47   7e-04
UniRef50_A6C348 Thymidylate kinase n=1 Tax=Planctomyces maris DS...    46   8e-04
UniRef50_B6YSZ4 Probable thymidylate kinase n=5 Tax=Thermococcac...    46   9e-04
UniRef50_Q45RR2 Deoxythymidylate kinase n=1 Tax=Cyprinid herpesv...    46   0.001
UniRef50_D1S998 Thymidylate kinase n=1 Tax=Micromonospora aurant...    46   0.001
UniRef50_A8LHM2 Thymidylate kinase n=8 Tax=Actinomycetales RepID...    46   0.001
UniRef50_Q4P9K7 Putative uncharacterized protein n=2 Tax=Fungi/M...    46   0.001
UniRef50_D1BLN7 Thymidylate kinase n=15 Tax=Bacteria RepID=D1BLN...    46   0.001
UniRef50_A4RZW8 Predicted protein n=13 Tax=Eukaryota RepID=A4RZW...    46   0.001
UniRef50_C6HZ31 Thymidylate kinase n=1 Tax=Leptospirillum ferrod...    46   0.001
UniRef50_Q254L6 Thymidylate kinase n=13 Tax=Chlamydiaceae RepID=...    45   0.002
UniRef50_C7PHF5 Thymidylate kinase n=1 Tax=Chitinophaga pinensis...    45   0.002
UniRef50_D2MMU9 dTMP kinase n=1 Tax=Bulleidia extructa W1219 Rep...    45   0.002
UniRef50_A8W246 Peptide chain release factor 2 n=1 Tax=Bacillus ...    45   0.002
UniRef50_Q93UI7 TMP kinase n=10 Tax=Candidatus Phytoplasma RepID...    45   0.002
UniRef50_A9BG59 Thymidylate kinase n=11 Tax=Bacteria RepID=A9BG5...    45   0.002
UniRef50_O67099 Thymidylate kinase n=2 Tax=Aquificaceae RepID=KT...    45   0.002
UniRef50_A3EQU8 Thymidylate kinase n=2 Tax=Leptospirillum sp. Gr...    45   0.002
UniRef50_B2GAE1 Thymidylate kinase n=32 Tax=Lactobacillales RepI...    45   0.002
UniRef50_Q970Q8 Probable thymidylate kinase n=12 Tax=Sulfolobace...    45   0.003
UniRef50_Q2FS90 Probable thymidylate kinase n=4 Tax=Methanomicro...    44   0.003
UniRef50_Q1PY20 Similar to thymidylate kinase n=1 Tax=Candidatus...    44   0.003
UniRef50_A8MB58 Probable thymidylate kinase n=3 Tax=Thermoprotea...    44   0.003
UniRef50_B4S1N2 Thymidylate kinase n=4 Tax=Alteromonadales RepID...    44   0.004
UniRef50_D2Q7V9 Thymidylate kinase n=2 Tax=Bifidobacterium denti...    44   0.004
UniRef50_C9SNG5 Thymidylate kinase n=7 Tax=Sordariomycetes RepID...    44   0.004
UniRef50_Q2RZ38 Thymidylate kinase n=2 Tax=Rhodothermaceae RepID...    44   0.006
UniRef50_Q1C6N6 Thymidylate kinase n=40 Tax=Enterobacteriaceae R...    44   0.006
UniRef50_UPI0001AECAE5 thymidylate kinase n=6 Tax=Streptomyces R...    43   0.007
UniRef50_Q1D6W4 Thymidylate kinase n=7 Tax=Cystobacterineae RepI...    43   0.007
UniRef50_B6BTX5 Thymidylate kinase n=1 Tax=beta proteobacterium ...    43   0.007
UniRef50_A0LF96 Thymidylate kinase n=1 Tax=Syntrophobacter fumar...    43   0.008
UniRef50_B1I165 Thymidylate kinase n=3 Tax=Firmicutes RepID=KTHY...    43   0.009
UniRef50_A5FR84 Thymidylate kinase n=5 Tax=Dehalococcoides RepID...    43   0.009
UniRef50_A0JSU5 Thymidylate kinase n=2 Tax=Micrococcaceae RepID=...    43   0.009
UniRef50_C4RPM7 Thymidylate kinase n=1 Tax=Micromonospora sp. AT...    43   0.010
UniRef50_Q6F0E1 Thymidylate kinase n=1 Tax=Mesoplasma florum Rep...    43   0.010
UniRef50_Q115I0 Thymidylate kinase n=10 Tax=Bacteria RepID=KTHY_...    42   0.011
UniRef50_A0RXT4 Thymidylate kinase n=1 Tax=Cenarchaeum symbiosum...    42   0.012
UniRef50_B0MX01 Putative uncharacterized protein n=1 Tax=Alistip...    42   0.012
UniRef50_O05891 Thymidylate kinase n=38 Tax=Actinomycetales RepI...    42   0.013
UniRef50_B2UBZ3 Thymidylate kinase n=13 Tax=Proteobacteria RepID...    42   0.014
UniRef50_D1S562 Thymidylate kinase n=1 Tax=Micromonospora aurant...    42   0.015
UniRef50_UPI0001BC6A77 thymidylate kinase n=1 Tax=Buchnera aphid...    42   0.020
UniRef50_B7GT80 Thymidylate kinase n=2 Tax=Actinobacteridae RepI...    42   0.023
UniRef50_Q1H169 Thymidylate kinase n=2 Tax=Methylophilales RepID...    41   0.026
UniRef50_Q1QX49 Thymidylate kinase n=11 Tax=Proteobacteria RepID...    41   0.027
UniRef50_Q1IJX5 Thymidylate kinase-like n=1 Tax=Candidatus Korib...    41   0.029
UniRef50_B0D7L7 Predicted protein n=2 Tax=Agaricales RepID=B0D7L...    41   0.034
UniRef50_D0LII3 Thymidylate kinase n=1 Tax=Haliangium ochraceum ...    41   0.037
UniRef50_C9RA68 Thymidylate kinase n=1 Tax=Ammonifex degensii KC...    41   0.038
UniRef50_D1WS25 Thymidylate kinase n=10 Tax=Actinomycetales RepI...    41   0.040
UniRef50_Q13YY3 Thymidylate kinase n=7 Tax=Burkholderiales RepID...    40   0.062
UniRef50_A2SN76 Thymidylate kinase n=3 Tax=Betaproteobacteria Re...    40   0.069

>UniRef50_Q46843 Uncharacterized ATP-binding protein yghS n=43
           Tax=Enterobacteriaceae RepID=YGHS_ECOLI
          Length = 237

 Score =  352 bits (903), Expect = 5e-96,   Method: Composition-based stats.
 Identities = 237/237 (100%), Positives = 237/237 (100%)

Query: 1   MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWI 60
           MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWI
Sbjct: 1   MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWI 60

Query: 61  SQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFL 120
           SQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFL
Sbjct: 61  SQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFL 120

Query: 121 LITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDE 180
           LITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDE
Sbjct: 121 LITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDE 180

Query: 181 QTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
           QTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS
Sbjct: 181 QTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237


>UniRef50_C8WFA2 Putative uncharacterized protein n=3 Tax=Zymomonas mobilis
           RepID=C8WFA2_ZYMMN
          Length = 256

 Score =  312 bits (800), Expect = 4e-84,   Method: Composition-based stats.
 Identities = 89/223 (39%), Positives = 128/223 (57%), Gaps = 1/223 (0%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           ++IA+VGCDGSGKS+LT  L+  +    P +  YLG  SG +G  I Q+PV+G+     L
Sbjct: 27  KLIALVGCDGSGKSSLTTDLIAAIQKYTPVKRYYLGLGSGDLGRKIGQIPVVGSWIENLL 86

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           + +A     K    PG +TALV+Y  S  R   + KM    + G  +ITDRYPQ E+ G 
Sbjct: 87  KQRATTTRTKGKKIPGVMTALVVYFFSLRRFCSYLKMRRALKAGITVITDRYPQAEIAG- 145

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
           + DGP L+    GN ++  L + E  LYQ MAS+ P L++RL +D +TA ARKPDH + A
Sbjct: 146 QCDGPGLSAAKAGNRFVSWLVRSEAALYQRMASFQPDLVLRLDVDPETAHARKPDHDIEA 205

Query: 195 LQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
           L+ K  +   LTF GA +  +D   P   + +  +R +   L+
Sbjct: 206 LRIKSEIMQHLTFGGAHMEVIDATRPYKAVWKDIVRLVQPYLT 248


>UniRef50_Q46844 Uncharacterized ATP-binding protein yghT n=39
           Tax=Enterobacteriaceae RepID=YGHT_ECOLI
          Length = 230

 Score =  302 bits (772), Expect = 1e-80,   Method: Composition-based stats.
 Identities = 79/222 (35%), Positives = 132/222 (59%), Gaps = 4/222 (1%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA++G DGSGKST+   L+  +      E ++LG+ +G +G  +++LP++G    + + 
Sbjct: 8   LIAVIGSDGSGKSTVCEHLITVVEKYGAAERVHLGKQAGNVGRAVTKLPLMGKSLHKTIE 67

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                  +K    PG + ALVI      R  +FR ML   ++G +++TDRYPQ ++PG  
Sbjct: 68  RNQVKTAKKL---PGPVPALVITAFVARRLLRFRHMLACRRRGLIVLTDRYPQDQIPG-A 123

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
           +DG        G  ++  L  +E K + WMAS+ P L+I+L +D + A ARKPDH+  +L
Sbjct: 124 YDGTVFPPNVEGGRFVSWLASQERKAFHWMASHKPDLVIKLNVDLEVACARKPDHKRESL 183

Query: 196 QEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
             KIA+TPQLTF GA+++++D   P +++L  + +AI   ++
Sbjct: 184 ARKIAITPQLTFGGAQLVDIDANQPLEQVLVDAEKAITDFMT 225


>UniRef50_P64573 Uncharacterized ATP-binding protein yghR n=42
           Tax=Enterobacteriaceae RepID=YGHR_ECOL6
          Length = 252

 Score =  293 bits (750), Expect = 3e-78,   Method: Composition-based stats.
 Identities = 94/217 (43%), Positives = 131/217 (60%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA+VGCDG+GKSTLT  LV  L     TE  YLG  SG  G+ I +LP++G    R L 
Sbjct: 23  LIAVVGCDGTGKSTLTTDLVKSLQQHWQTERRYLGLLSGEDGDKIKRLPLVGVWLERRLA 82

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           +K++      +  P    A+++Y  S  R    RK+   +Q G L+++DR+PQ E+ GF 
Sbjct: 83  AKSSKTQSMKTKSPALWAAVIMYCFSLRRMANLRKVQRLAQSGVLVVSDRFPQAEISGFY 142

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
           +DGP +            L QRE +LYQ MA Y P L+IRLGID +TA +RKPDH  A L
Sbjct: 143 YDGPGIGVERATGKISMFLAQRERRLYQQMAQYRPELIIRLGIDIETAISRKPDHDYAEL 202

Query: 196 QEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAI 232
           Q+KI V  ++ +NG KILE+D R P  E+L+ + +A+
Sbjct: 203 QDKIGVMSKIGYNGTKILEIDSRAPYSEVLEQAQKAV 239


>UniRef50_Q5NMW8 Conserved predicted protein with nucleoside triphosphate hydrolase
           domain n=3 Tax=Zymomonas mobilis RepID=Q5NMW8_ZYMMO
          Length = 240

 Score =  285 bits (729), Expect = 9e-76,   Method: Composition-based stats.
 Identities = 84/217 (38%), Positives = 131/217 (60%), Gaps = 3/217 (1%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA+VG DGSGK+T+   L+  L    PT   +LG+ +G  G  I+++P +G    + + 
Sbjct: 14  LIALVGADGSGKTTVGQELLEWLQTMRPTAFCHLGKQTGNWGRAIARMPFVGRKLDKQVI 73

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           ++++   ++     G   ++VI+ LS  R ++F +M    ++GF+++TDRYPQ  VPG  
Sbjct: 74  ARSSKARDEKGA--GATVSIVIFALSMRRVFRFLRMRRLHRKGFMILTDRYPQAVVPG-P 130

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
            DGP L          + L  RE  LY WMASY P ++IRL +D +TA  RKPDH+ A+L
Sbjct: 131 MDGPGLVARNPKGMIARFLTGREQALYDWMASYKPDIVIRLNVDLETALKRKPDHRPASL 190

Query: 196 QEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAI 232
           + K+   P+L+FNGA IL+LD R P D+++  +  AI
Sbjct: 191 ERKVRDVPRLSFNGAPILDLDSREPLDQVIGKAKAAI 227


>UniRef50_Q2LPR0 Hypothetical cytosolic protein n=1 Tax=Syntrophus aciditrophicus SB
           RepID=Q2LPR0_SYNAS
          Length = 487

 Score =  253 bits (647), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 56/226 (24%), Positives = 98/226 (43%), Gaps = 11/226 (4%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQ-SSGRIGEWISQLPVIGAPFGRYL 74
           +IAIVG DG+GK+T+   +   L  +     +++G+ +  R     S    IG   G Y 
Sbjct: 268 LIAIVGGDGAGKTTVIEEVHKWLGRKFDVMKLHMGKPARSRTTILGSGFLKIGTMLGLY- 326

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
               A ++ + +  PG    + +  L+  R   + K    +  G L+I DRY   ++   
Sbjct: 327 -PATADLYAEEAEFPGYPFLIRMVFLAYDRYLTYLKARRFASNGGLVICDRYFLADL--L 383

Query: 135 RFDGPQ---LAKTTG-GNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH 190
             DGP+   +AK     N ++  L + E   Y+ M S  P LLI L ++ + A  RK D 
Sbjct: 384 TMDGPRCKMMAKAFNRSNFFMNWLIRIEASCYEKMMS--PDLLIVLRLNPEIAVQRKTDE 441

Query: 191 QLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
              +++ +     +  ++      +D   P +E+L      I   L
Sbjct: 442 TAVSVRARSTSIWEYDWSKTSACVVDSSRPKEEVLAQVQSLIWRYL 487


>UniRef50_D2A7H7 Putative ATP-binding protein yghT n=3 Tax=Enterobacteriaceae
           RepID=D2A7H7_SHIF2
          Length = 131

 Score =  191 bits (484), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 50/127 (39%), Positives = 82/127 (64%), Gaps = 1/127 (0%)

Query: 111 MLCKSQQGFLLITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLP 170
           ML   ++G +++TDRYPQ ++PG  +DG        G  ++  L  +E K + WMAS+ P
Sbjct: 1   MLACRRRGLIVLTDRYPQDQIPG-AYDGTVFPPNVEGGRFVSWLASQERKAFHWMASHKP 59

Query: 171 VLLIRLGIDEQTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLR 230
            L+I+L +D + A ARKPDH+  +L  KIA+TPQLTF GA+++++D   P +++L  + +
Sbjct: 60  DLVIKLNVDLEVACARKPDHKRESLARKIAITPQLTFGGAQLVDIDANQPLEQVLVDAEK 119

Query: 231 AIHAALS 237
           AI   ++
Sbjct: 120 AITDFMT 126


>UniRef50_D2RGJ1 Thymidylate kinase n=2 Tax=Archaeoglobaceae RepID=D2RGJ1_ARCPR
          Length = 199

 Score = 65.1 bits (157), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 48/229 (20%), Positives = 79/229 (34%), Gaps = 49/229 (21%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA+ G DGSGK+T+   LV EL  R      +   +    G+ I Q+        R + 
Sbjct: 2   LIAVEGIDGSGKTTIVRFLVEELKKRGYDVVAFKEPTDSEYGKKIRQILK-----ERKIS 56

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQVEVPGF 134
            +                   + L    R +  R  +L   + G ++I DRY    +   
Sbjct: 57  PEEE-----------------LKLFIKDREFNVRNNILPALKSGKVVIMDRYYYSTIAYQ 99

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF-----ARKPD 189
              G  + K    N                     P L+I L +  +TA       RKPD
Sbjct: 100 GALGLDIGKIKTLNEQFP----------------KPDLVIILDVSPETALKRIKAKRKPD 143

Query: 190 --HQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
               L  L++   +   L      I+ +D     +E+ +  L+ +   L
Sbjct: 144 RFEDLEYLRKVRNIFLSL---KNNIVVIDAERDIEEVKRDVLKVVLEHL 189


>UniRef50_C5KB73 Thymidylate kinase, putative n=2 Tax=Perkinsus marinus ATCC 50983
           RepID=C5KB73_9ALVE
          Length = 233

 Score = 63.2 bits (152), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 46/229 (20%), Positives = 77/229 (33%), Gaps = 42/229 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G D SGKST    +   L  R   E + +G           +   IG     YLR
Sbjct: 6   FIVLEGLDRSGKSTQLRRISEALRQRTGKEVVEMGFPR--------RSSAIGKMLDTYLR 57

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
             ++ + ++           V  L S  R     +ML     G  ++ DRY    V    
Sbjct: 58  DSSSKMRDEA----------VHLLFSANRWEAMSEMLSHLAAGRHIVCDRYIFSGVAYTA 107

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----KPDHQ 191
             G             +  +  ++ L        P L++ L +  + A  R    +  ++
Sbjct: 108 MKGTV---------DFEWCKSVDVGL------PKPDLVVFLDLSPEAAAKRGAYGEERYE 152

Query: 192 LAALQEKIAVTPQLTFNGAKILEL-DGRHPADEI---LQASLRAIHAAL 236
              LQ K+       F       + D   PA+E+   +  +  A+  AL
Sbjct: 153 KEDLQMKVRTMYT-KFEKEPFWRIFDADRPAEEVTRTVTDAAVAVAQAL 200


>UniRef50_Q1J3J7 Thymidylate kinase-like protein n=1 Tax=Deinococcus geothermalis
           DSM 11300 RepID=Q1J3J7_DEIGD
          Length = 436

 Score = 62.4 bits (150), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 50/220 (22%), Positives = 81/220 (36%), Gaps = 36/220 (16%)

Query: 17  IAIVGCDGSGKSTLTASLVNELA-ARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +A +G DG+GKS++ A + N++A A    +  +L  S GR           G P G  + 
Sbjct: 234 VAFLGPDGAGKSSVIAEVENKVAPAFRRLKRYHLRPSFGR-----------GHPSGEAV- 281

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQV---EVP 132
              +  H K     G+  A ++  L+ +       +     +  L+I DRY      +  
Sbjct: 282 ---SDPHGKAPRGSGSSLAKLLLWLADYTVGSVPAVRLPLVRSTLVIFDRYYHDLLVDAR 338

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQL 192
            +R+ GP              L     +     A   P L I L +  + A ARKP+  L
Sbjct: 339 RYRYGGP------------AWLAGLVGR-----AVPRPDLFIFLDLPAEVAHARKPEVPL 381

Query: 193 AALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAI 232
              +       QL         +D   P DE+ +     I
Sbjct: 382 EEGRRLRERYRQLARQLPNAHVVDAERPLDEVAREVETII 421


>UniRef50_Q8SS22 THYMIDYLATE KINASE n=1 Tax=Encephalitozoon cuniculi
           RepID=Q8SS22_ENCCU
          Length = 191

 Score = 57.8 bits (138), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 42/223 (18%), Positives = 74/223 (33%), Gaps = 43/223 (19%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           + +   G D SGK+T+  SL   L   +PT  I     SG +G+ I              
Sbjct: 5   KFVVFEGLDRSGKTTIVGSLYESLLPIVPTSKIRFPNRSGPVGKIIDGYL---------- 54

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
             K  ++  +           +  L S  R  + R M+ + ++  +++ DRY        
Sbjct: 55  -QKKTNLESE----------TIHLLFSADRY-EHRLMIEELRRDTIILCDRYSMS----- 97

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK----PDH 190
                 +A +      +      E  L        P L I + +       RK      H
Sbjct: 98  -----GIAYSVAKGLSLDWCIASEALL------PKPDLTIFIDVPMDEICRRKGFGTEIH 146

Query: 191 QLAALQEKIAVTPQLTFNGAK-ILELDGRHPADEILQASLRAI 232
                 +K+    Q      +  L +DG  P  E+++   + I
Sbjct: 147 DTVPFLKKVLSAYQALLKKEENTLVVDGTLPVREVVEIVRKRI 189


>UniRef50_B8D357 Thymidylate kinase n=1 Tax=Desulfurococcus kamchatkensis 1221n
           RepID=B8D357_DESK1
          Length = 206

 Score = 57.8 bits (138), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 37/230 (16%), Positives = 70/230 (30%), Gaps = 49/230 (21%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARM-PTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
            I + G DG+GK+T+   LV +L++R  P  + Y                    P    +
Sbjct: 7   FIVLEGLDGAGKTTVARRLVEDLSSRGIPASYTY-------------------EPTDSEI 47

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPG 133
                  +         I AL     +  R    +  +     +G  +I+DRY    V  
Sbjct: 48  VRVIKSTYNNLRD--AYIDAL---AFALDRLIHVKNWVKPLLDKGVTVISDRYFYSSVAY 102

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK------ 187
               G         N +                   P + I L I+ +   +RK      
Sbjct: 103 QSASGAPFEWVIEVNKFA----------------MKPDVAIYLDIEPEEGLSRKHMHTSR 146

Query: 188 -PDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
            P+++     +++            ++ +D   P  E+       ++  L
Sbjct: 147 FPEYEEKEFLQRVRSMYLRMVEMGLLIYIDASKPLSEVYGRIWDIVYGRL 196


>UniRef50_A1RTS9 Thymidylate kinase n=3 Tax=Thermoproteaceae RepID=A1RTS9_PYRIL
          Length = 205

 Score = 55.9 bits (133), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 44/231 (19%), Positives = 80/231 (34%), Gaps = 52/231 (22%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            +AI G DGSGKST+   L   L     T       S G IG  I +  + G     ++ 
Sbjct: 3   FVAIEGIDGSGKSTVILQLAEMLPKVYVTRE----PSGGPIGRLIKEWALKGGTIDPHVD 58

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEVPGF 134
           +                      L +  R   + R++  K ++G+++I++RY +  +   
Sbjct: 59  A---------------------LLFAADRIEHYKREIEPKVREGYIVISERYIESSIA-- 95

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-------- 186
            + G           +IK++           A     + I L +D + A AR        
Sbjct: 96  -YQGAAGVPID----FIKIINS---------AVPKADITIILDVDPEIAIARIKQRGDSE 141

Query: 187 KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
           K +H     + +     +    G     +D   P + + +     I   L+
Sbjct: 142 KYEHSAFLKRVREIYLQRAREEGYP--VVDASRPPNVVAKDVAEIITQMLN 190


>UniRef50_O30175 Probable thymidylate kinase n=1 Tax=Archaeoglobus fulgidus
           RepID=KTHY_ARCFU
          Length = 196

 Score = 55.5 bits (132), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 40/231 (17%), Positives = 81/231 (35%), Gaps = 51/231 (22%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA+ G DG+GK+T+ A +   L  +     + + +  G             + FG+ ++
Sbjct: 2   LIAVEGIDGAGKTTIAAYIAELLKEKG--YKVKVLKEPGD------------SKFGKKIK 47

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
           S    +  +            + L    R    R+ +L   Q G+ ++ DRY    +   
Sbjct: 48  SSEERLSPEEE----------LELFLKDREIDARENILPALQSGYAVVMDRYYFSNIAYQ 97

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWM---ASYLPVLLIRLGIDEQTAFARKPDHQ 191
              G                   + +L + M    +  P L I L ++ + A  R     
Sbjct: 98  SARG------------------IDARLIREMNEKIAPKPDLTILLDVEPEIALERVRKRG 139

Query: 192 LAALQEKIAVTPQ-----LTFNGAKILELDGRHPADEILQASLRAIHAALS 237
             +  EK+    +     L       + +D   P +E+ +   + I + L+
Sbjct: 140 KLSPFEKLDYLRKVRKCFLENADETTVVVDASKPLEEVKEEVRKVIESFLN 190


>UniRef50_B5IF40 Thymidylate kinase n=2 Tax=Aciduliprofundum boonei T469
           RepID=B5IF40_9EURY
          Length = 197

 Score = 54.3 bits (129), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 42/225 (18%), Positives = 75/225 (33%), Gaps = 37/225 (16%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G DGSGKST+   +   L++      I+L +                   G+ +R
Sbjct: 2   FIVFEGIDGSGKSTIAKRIAEHLSSLG--HKIFLTEEPTT------------TWMGKDVR 47

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                   +    P +   L        RA     +    + G ++I+DRY       F 
Sbjct: 48  RAI-----EEEKNPLSQALL----FFADRAEHVEAIKKNLEDGKIVISDRY---VYSTFA 95

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF----AR--KPD 189
           + G Q+ K    +  +K L      +Y+ M    P ++I L I+ +        R  K  
Sbjct: 96  YQGAQMEKLMPLDKALKWLEG----VYEPM-RLDPDMVILLKIEPRRGLDFVNTRDFKEK 150

Query: 190 HQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHA 234
            +     E++        +      +D     +E+     + I A
Sbjct: 151 FEREEFLERVQDIYMALADKYGFFVVDSNRNLNEVYDDVRKIIDA 195


>UniRef50_Q17LP5 Thymidylate kinase, putative n=4 Tax=Culicidae RepID=Q17LP5_AEDAE
          Length = 249

 Score = 53.2 bits (126), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 40/182 (21%), Positives = 60/182 (32%), Gaps = 37/182 (20%)

Query: 5   NMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLP 64
           NMSII      +I + GCD +GK+T    +V  L +                 +  +Q  
Sbjct: 39  NMSIIQKRGA-LIVLEGCDRAGKTTQCKRIVESLNSAGHKAKFM------NFPDRSTQF- 90

Query: 65  VIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITD 124
             GA    YL SK     E            +  L +  R     +M    + G  LI D
Sbjct: 91  --GALINSYLTSKDNFTDEA-----------IHLLFTLNRWEAKNEMERLLRSGVTLIVD 137

Query: 125 RYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF 184
           RY         + G   +   G N  +   +  E  L        P L++ L +  +   
Sbjct: 138 RY--------SYSGVAFSAAKGLN--MDWCKAPETGL------PKPDLVLLLTLTAEAMA 181

Query: 185 AR 186
            R
Sbjct: 182 KR 183


>UniRef50_Q1NTS0 Putative uncharacterized protein n=1 Tax=delta proteobacterium
           MLMS-1 RepID=Q1NTS0_9DELT
          Length = 502

 Score = 53.2 bits (126), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 43/223 (19%), Positives = 73/223 (32%), Gaps = 31/223 (13%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
           +P+  IAIVG DG GK+T+   LV+      P    ++   +       + LP       
Sbjct: 261 SPLPAIAIVGNDGCGKTTVCEELVSICYKMDPV---HINMRTD-----ATVLPWTPTLRS 312

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQG-FLLITDRYPQVE 130
              +     +  K       +  L        +  +FR  +  +  G  + I +RYP   
Sbjct: 313 VLKKLARVGLFRKNRFFKQAVGLLGELNDVFDKFVRFRLGMAWADSGLGVTIFERYPTDR 372

Query: 131 VPG-FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP- 188
           V G F  D             IK     E          LP  +I L +  +    RK  
Sbjct: 373 VRGEFPHD------------IIKWWP-IEQFF------PLPDGIIYLDVSPEDTLKRKSC 413

Query: 189 -DHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLR 230
             H +  ++ K      L    +   ++D     +E +    +
Sbjct: 414 DGHTVDEMKSKRDNYLSLLREFSTAFKVDNGMSKEETISVVKK 456


>UniRef50_Q67JB0 Thymidylate kinase n=1 Tax=Symbiobacterium thermophilum
           RepID=KTHY_SYMTH
          Length = 214

 Score = 53.2 bits (126), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 37/230 (16%), Positives = 73/230 (31%), Gaps = 39/230 (16%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I+  G DGSGKST    L+  L     +      +  G            G P    +R
Sbjct: 4   FISFEGVDGSGKSTQIRLLLQYLDE--QSVPYVFTREPG------------GTPIAEQIR 49

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                   +  +    +    +   +    +  R +    ++G ++I DR+         
Sbjct: 50  RVLLDPANRGMS----VITEALLFAAARAEHVSRTIRPALEEGKVVICDRF--------- 96

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
            D   + +   G   ++ L Q          +  P   I L +  + A AR+   +   +
Sbjct: 97  VDSSLVYQGVAGGLPVEFLTQINEMA---TGALRPHRTIVLDLAPEVALARRTGEEADRI 153

Query: 196 QEKIAVTPQLTFNG---------AKILELDGRHPADEILQASLRAIHAAL 236
           + +     QL   G          ++  +D     +E+ +   R +   L
Sbjct: 154 ERQSREYHQLVREGYLDLARAEPRRVKVVDASRSVEEVQKDIRRLVEEVL 203


>UniRef50_Q3B752 Zgc:123174 n=5 Tax=root RepID=Q3B752_DANRE
          Length = 212

 Score = 52.8 bits (125), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 38/229 (16%), Positives = 67/229 (29%), Gaps = 59/229 (25%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I + G D +GK+T    LV  +              +  I  +  +   IG     YL 
Sbjct: 8   LIVLEGVDRAGKTTQCQKLVQAIQQSG---------RAAEIMRFPDRTTKIGQLISSYLE 58

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
            K+                 V  L S  R      M  K ++G  L+ DRY         
Sbjct: 59  KKSN-----------LEDHTVHLLFSANRWEMVPVMKQKLEEGINLVVDRY--------A 99

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQT------------- 182
           F G        G   ++     ++ L        P L++ L ++                
Sbjct: 100 FSGVAFTSAKPG-FSLEWCMNPDVGL------PKPDLVMFLQLNPNVAANRGEYGNERYE 152

Query: 183 --AFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASL 229
             AF R    +   L +  ++  +          +D     +E+ +   
Sbjct: 153 TSAFQRTVQQRFEELMQDTSINWK---------VIDAARTIEEVHKDIK 192


>UniRef50_Q1NU71 Putative uncharacterized protein n=1 Tax=delta proteobacterium
           MLMS-1 RepID=Q1NU71_9DELT
          Length = 432

 Score = 52.8 bits (125), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 48/223 (21%), Positives = 81/223 (36%), Gaps = 21/223 (9%)

Query: 8   IINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIG 67
           IIN   + V+A+ G DGSGKST     ++ L   +P E   L       G    +     
Sbjct: 214 IINKKGI-VVAVEGIDGSGKST----FIDVLNKSIPKEGRELFVQKSMAGRGFWRYSNKI 268

Query: 68  APFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYP 127
               R    +   ++       G +  + I  +     + F +       G  +I DRY 
Sbjct: 269 RTIWRRSCDRPGKMNSVLKN--GLLPIVFIIEIG-SLYFLFLRSRQLKNSGKNVIFDRY- 324

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK 187
              +   R       +  G N +I++L    ++   W  S  P + + L +D   A+ RK
Sbjct: 325 -ACLHYIRQRVHNKNRFVGKNLYIQLLYLLSVR---WFPS--PDVFVYLNVDPLVAYERK 378

Query: 188 PDHQLAALQEKI-----AVTPQLTFNGAKILELDGRHPADEIL 225
            +  +  L EK       V P       +   +D   P + I+
Sbjct: 379 KEDHVDELMEKYLIYNKEVVPLYD-KITECFIVDSTLPTEVIV 420


>UniRef50_B4CTS9 Putative uncharacterized protein n=1 Tax=Chthoniobacter flavus
           Ellin428 RepID=B4CTS9_9BACT
          Length = 443

 Score = 52.4 bits (124), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 45/210 (21%), Positives = 81/210 (38%), Gaps = 32/210 (15%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           R I  VG DG GK+T+   L+ E          +          WI   P    P    +
Sbjct: 233 RWIVFVGPDGVGKTTVATLLLAETKDFFRGARYH---------HWI---PPWQKPLTSTV 280

Query: 75  RSKAAH--VHEKPSTPPGNITA---LVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQV 129
            + A    + ++P+     I++   LV  +     AY FR +    +Q  L+I DRY   
Sbjct: 281 PASAPKPPLRDRPAGTGATISSALRLVRNVFRAHLAYCFRILPQLLRQR-LVIGDRY--- 336

Query: 130 EVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD 189
            +  +  D P+  +  G + W++   +             P L++ L  D +    RKP+
Sbjct: 337 -LFNYHLD-PESVRYYGPSSWVRFALR---------FVPKPDLVLCLVADPEEIHRRKPE 385

Query: 190 HQLAALQEKIAVTPQLTFNGAKILELDGRH 219
             L  ++  I+   +L+  G   +++    
Sbjct: 386 LSLDEIRRVISRGEELSSIGFHAVQIRAEE 415


>UniRef50_P36590 Thymidylate kinase n=2 Tax=Ascomycota RepID=KTHY_SCHPO
          Length = 210

 Score = 52.4 bits (124), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 45/227 (19%), Positives = 84/227 (37%), Gaps = 45/227 (19%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           R+I I G D SGKST    LV++L      E   L +   R          IG     YL
Sbjct: 8   RLIVIEGLDRSGKSTQCQLLVDKL--ISQHEKAELFKFPDRTT-------AIGKKIDDYL 58

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           + ++  ++++          ++  L S  R    + +  +  +G   I DRY        
Sbjct: 59  K-ESVQLNDQ----------VIHLLFSANRWETIQYIYEQINKGVTCILDRY-------- 99

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----KPDH 190
            F G   +   G +   +  +  +  L        P L+I L +D + A  R    +  +
Sbjct: 100 AFSGIAFSAAKGLDW--EWCKSPDRGL------PRPDLVIFLNVDPRIAATRGQYGEERY 151

Query: 191 QLAALQEKI-----AVTPQLTFNGAKILELDGRHPADEILQASLRAI 232
           +   +QEK+      +  +    G + + LD     +++    +  +
Sbjct: 152 EKIEMQEKVLKNFQRLQKEFREEGLEFITLDASSSLEDVHSQIVDLV 198


>UniRef50_B1V9T6 Thymidylate kinase n=9 Tax=16SrXII (Stolbur group)
           RepID=B1V9T6_PHYAS
          Length = 215

 Score = 52.0 bits (123), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 37/190 (19%), Positives = 68/190 (35%), Gaps = 41/190 (21%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           ++I+  G DGSGK+TL   L      +     ++ G  S  +G+ I  L +  +      
Sbjct: 4   KLISFEGVDGSGKTTLINELKKYFENKGYQIKVFQGLGSSIVGKEIRNLFLHQSKISPKT 63

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           +   +  +   +     I AL+                     G+L++ DR+        
Sbjct: 64  KYLLSLANMLQTQDELIIPALL--------------------SGYLVLVDRWY------- 96

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASY---LPVLLIRLGIDEQTAFARK---P 188
              G   A  + GN         + K+   + ++    P L   L ID +    RK    
Sbjct: 97  ---GSTFAYQSKGNY-----IDYDDKITSKIINHFLIKPKLTFYLDIDPKIGIQRKQNQT 148

Query: 189 DHQLAALQEK 198
           +H+L  ++ K
Sbjct: 149 NHKLDLIERK 158


>UniRef50_UPI0001C375B1 putative thymidylate kinase n=1 Tax=Ruminococcus flavefaciens FD-1
           RepID=UPI0001C375B1
          Length = 224

 Score = 52.0 bits (123), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 35/176 (19%), Positives = 62/176 (35%), Gaps = 37/176 (21%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           ++I I G DGSGK+T TA L  +L      E  +           +    ++        
Sbjct: 4   KLIVIEGLDGSGKATQTALLCEKLKTLG-VEFDHFSFPDYNSESSL----LVRMYLDGKF 58

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQ----- 128
              AA V+   ++             +C R   FR +   K + G +++ DRY       
Sbjct: 59  GDNAAEVNPYAASC----------FFACDRYASFRTQWQDKYEGGHIIVCDRYTTSNAVH 108

Query: 129 --VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQT 182
              ++P   +D            ++  L   E   Y+ +    P  +I L +D + 
Sbjct: 109 QCSKLPDGEWDD-----------FVNWLFDFE---YRKIGLPEPDAVIYLRVDPEI 150


>UniRef50_A3CPJ9 Thymidylate kinase n=29 Tax=Firmicutes RepID=KTHY_STRSV
          Length = 212

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 41/230 (17%), Positives = 78/230 (33%), Gaps = 42/230 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I++ G +G+GKS++  +L+  L           G  +         + +  A     L 
Sbjct: 6   LISLEGPEGAGKSSVLEALLPFLQNYGT------GLIT---TREPGGVQIAEAIREVILE 56

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                +  K        T L++Y+ S  +    R +   +Q G L++ DR+    V    
Sbjct: 57  PSHTAMDAK--------TELLLYIASRRQHLTERVLPALAQ-GKLVLMDRFIDSSVAYQG 107

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
           + G  L         I+ L Q             P L +   ID +   AR    +   +
Sbjct: 108 Y-GRGLDVAD-----IEWLNQFATD------GLKPDLTLYFDIDVEEGLARIAKSESREV 155

Query: 196 ------------QEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIH 233
                       + +      L     + +++D   P D+++  SL  I 
Sbjct: 156 NRLDLEGLDLHQRVRQGYLAILDKEPERFVKVDASQPLDKVVADSLAIIQ 205


>UniRef50_A5N3T4 Tmk n=32 Tax=Bacteria RepID=A5N3T4_CLOK5
          Length = 228

 Score = 51.6 bits (122), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 38/243 (15%), Positives = 80/243 (32%), Gaps = 43/243 (17%)

Query: 15  RVIAIVGCDGSGKSTLTASLVN-ELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
           ++I I GCDGSGK+T T  L N  L  +   + +     +      +             
Sbjct: 7   KLIVIEGCDGSGKATQTRKLYNRLLDEKYNVKKVEYPNYNSESSALVKMYL--------- 57

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQVEVP 132
                    E P      + +         R   ++ +     + G ++++DRY      
Sbjct: 58  ----NGDFGENPEDVSAYVAS---TFYGVDRFASYKTQWKKFYEGGGIVLSDRY---TTS 107

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQ----------- 181
                  ++      + ++K L   E  +++     +P  +I L +  +           
Sbjct: 108 NMVHQASKIDNIEEKDKFLKWLWDFEFNIFKL---PVPDCVIFLDMPPEYSKNLMIERNN 164

Query: 182 --TAFARKPDHQ------LAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIH 233
             T  A+K  H+      + +    + V  +  +N    +E D  +  +EI +     + 
Sbjct: 165 KFTGNAKKDIHESNYEYLINSYNNAVYVADKYGWNKISCIENDRINTVNEIHKNIYSLVK 224

Query: 234 AAL 236
             L
Sbjct: 225 YIL 227


>UniRef50_C4DQR2 Thymidylate kinase n=1 Tax=Stackebrandtia nassauensis DSM 44728
           RepID=C4DQR2_9ACTO
          Length = 204

 Score = 51.6 bits (122), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 47/228 (20%), Positives = 71/228 (31%), Gaps = 49/228 (21%)

Query: 17  IAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLRS 76
           IA+VG DG+GK+T    L   L          +                     GR +  
Sbjct: 10  IALVGIDGAGKTTQARWLKRWLTQLGHPVRYRM------------------VASGRRVLG 51

Query: 77  KAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFRF 136
             A    +P +       + I   +  R +     L     G +LI DRY   +    R 
Sbjct: 52  NTARRLGRPDSVALLGPGMAIRAETLLRYWN----LTVGNGGGILIADRYAVCQYARTRV 107

Query: 137 DGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR--------KP 188
             P+L        W + L  R            P L + L +  +TA  R        +P
Sbjct: 108 VYPRLEP------WARRLLGR---------VPPPDLTLYLDVAPETAHLRVKTRGIDEEP 152

Query: 189 DHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
              LAA+       P+     A    +D     +EI +     +  AL
Sbjct: 153 VDSLAAMDSAYRSLPEF----ASFAIVDANRDPEEIAETIRDEVRTAL 196


>UniRef50_Q5ZVP1 Thymidylate kinase n=5 Tax=Legionella RepID=KTHY_LEGPH
          Length = 212

 Score = 50.9 bits (120), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 39/240 (16%), Positives = 76/240 (31%), Gaps = 44/240 (18%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAAR---MPTEHIYLGQSSGRIGEWISQLPV 65
           ++S   ++I I G +G+GKST    +V  L+ +     T     G   G I   I + P 
Sbjct: 1   MSSLTGKLIVIEGLEGAGKSTAVNLVVELLSQKKISTITTREPGGTKIGEILRSIIKNPE 60

Query: 66  IGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDR 125
                                         ++ L +       + +      G  +I DR
Sbjct: 61  YNNVLDDRSE--------------------LLLLYAARIQLIEQVIKPALNVGQWVIADR 100

Query: 126 YPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA 185
           +   E+    + G        G   + M    EL  +  +  + P L + L I+ +    
Sbjct: 101 F---ELSTLAYQG--------GGRKMDMRVINELSNF-CLKGFKPDLTLYLDINPELGMI 148

Query: 186 R--------KPDHQLAALQEKIAVTPQLTFNGAK-ILELDGRHPADEILQASLRAIHAAL 236
           R        + + +      +I  T  +       I+ +D     +E+  +    I   +
Sbjct: 149 RAKSRGKFDRIEQESIEFFHRIHDTYHILVKQNPEIIMIDANRSLEEVQSSIQSVIEEFI 208


>UniRef50_C0EEB4 Putative uncharacterized protein n=1 Tax=Clostridium methylpentosum
           DSM 5476 RepID=C0EEB4_9CLOT
          Length = 205

 Score = 50.5 bits (119), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 50/235 (21%), Positives = 74/235 (31%), Gaps = 45/235 (19%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           + I   G DGSGK T    L  E   R         Q +      ++   +  A  G + 
Sbjct: 3   KFIVFEGLDGSGKGTQIRLLCEEFKRRGEAF-----QQTAEPTFSVTGGAIRDALNGNHP 57

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           R             P  + AL +         KF  +     QG  +I DRY       F
Sbjct: 58  RH------------PAELAALFLTDRIYHNTGKFDGIELLLSQGKHVICDRYY---YSSF 102

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
            + G            ++ + +  L          P L I L +D Q + AR  D    +
Sbjct: 103 AYQGTGCD--------MQWVMEMNLNCPN---IRKPDLCIYLDVDPQRSKAR-VDGANKS 150

Query: 195 LQEKIAVTPQLT-----FNGA--------KILELDGRHPADEILQASLRAIHAAL 236
           L+       Q+T     F  A         I+ +D   P DE+      A+   L
Sbjct: 151 LEIFEQDIAQITAIRNKFMKAFELLGERETIVLIDADRPVDEVAADVWDAVKRIL 205


>UniRef50_A8Q2K3 Putative uncharacterized protein n=1 Tax=Malassezia globosa CBS
           7966 RepID=A8Q2K3_MALGO
          Length = 520

 Score = 50.5 bits (119), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 46/231 (19%), Positives = 76/231 (32%), Gaps = 48/231 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G D SGKST    LV  L                R+ ++  +   IG+    YL+
Sbjct: 313 FIVVEGLDRSGKSTQVDRLVQTLGP------------RARLVKFPERTTPIGSMIHSYLK 360

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                  ++           V  L S  R      ++   + G  +I DRY         
Sbjct: 361 -NQTDACDQ----------TVHLLFSANRWELLSSIVQSLRDGQHVICDRYIFS------ 403

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP--DHQLA 193
                +A T      +      ++ L       +P L + L +DE TA  R    + +  
Sbjct: 404 ----GMAYTHAKGLDLAWCTAPDVGL------PVPDLTLFLDLDESTATKRAAYGEERYE 453

Query: 194 A------LQEKIAVTPQLTF-NGAKILELDGRHPADEILQASLRAIHAALS 237
                  ++       QL   +GA+   LD     D++ QA    +   +S
Sbjct: 454 RRAFQRLVRHAFENVEQLMLRSGARWERLDASGTLDDVWQAVHAQVQEVVS 504


>UniRef50_Q9HLZ2 Probable thymidylate kinase n=2 Tax=Thermoplasma RepID=KTHY_THEAC
          Length = 193

 Score = 50.1 bits (118), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 47/231 (20%), Positives = 81/231 (35%), Gaps = 54/231 (23%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            IAI G DG+GK+TL   + N L        +Y+ +      E  +     G     +L+
Sbjct: 2   FIAIEGIDGAGKTTLARGIGNML--LGEGYRVYMTKEPTDGMENYA-----GDGVELFLK 54

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                                    +  R    R++    + G ++I DRY +     ++
Sbjct: 55  ------------------------FTINRYAHQREIDRHIKNGEIVICDRYIRSSYA-YQ 89

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMAS------YLPVLLIRLGIDEQTAFARKPD 189
           F+G             +     E K ++WM S        P + I + +DE+TA  R   
Sbjct: 90  FEG-----------IAEFFGNSE-KAWEWMDSVSEIIKIRPDVQIYVDVDEETAMERISR 137

Query: 190 HQLA----ALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
             L       ++K+    Q+       L +DG    + I+  +   I A L
Sbjct: 138 RGLRNPHFENEQKLRSVRQIYKGFQWDLIVDGGRDKEAIISETFEKIIARL 188


>UniRef50_C1BRK2 Thymidylate kinase n=1 Tax=Caligus rogercresseyi RepID=C1BRK2_9MAXI
          Length = 216

 Score = 50.1 bits (118), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 37/181 (20%), Positives = 58/181 (32%), Gaps = 42/181 (23%)

Query: 9   INSTPVR---VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPV 65
           ++S+ V+    I + GCD SGK+T+   L +           +  + S   G  I+    
Sbjct: 1   MSSSAVKRGAFIVLEGCDRSGKTTIAKRLSDSPGFEF---FRFPDRDSPLTGSLINSFLT 57

Query: 66  IGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDR 125
            G P                         L+  L S  R  K   ML     G  +I DR
Sbjct: 58  GGTPMSSQ---------------------LIHLLFSANRWEKVPSMLSVLSAGKNIICDR 96

Query: 126 YPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA 185
           Y         + G   + +  G  +       +  L        P L+I L +  + A  
Sbjct: 97  Y--------AYSGIAYSSSKPGMDF-DWCAGPDNGL------PTPDLVIFLDVSPEQALK 141

Query: 186 R 186
           R
Sbjct: 142 R 142


>UniRef50_Q0A8S2 Thymidylate kinase n=16 Tax=Gammaproteobacteria RepID=KTHY_ALHEH
          Length = 217

 Score = 50.1 bits (118), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 42/235 (17%), Positives = 83/235 (35%), Gaps = 43/235 (18%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           R I + G +G+GKST    +   L  +              I   +++ P  G P G  +
Sbjct: 5   RFITLEGLEGAGKSTALTRVREYLQRQG-------------IDAVMTREPG-GTPLGERI 50

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           R+    +    S PP       + + +    +  +++    ++G  ++ DR+       +
Sbjct: 51  RA----LLLGQSEPPMAPATEALLMFAARSEHLDKRIWPALERGQWVVCDRFTDA---SY 103

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQW-MASYLPVLLIRLGIDEQTAFARKPDHQLA 193
            + G                 +R   L  W   +  P L + L +  +T  AR      A
Sbjct: 104 AYQGWGRGLG----------AERIAALEDWTQGALRPDLTLWLDVPVETGLARAAGRGEA 153

Query: 194 A---LQEKIAVTPQLTFNGAKILE--------LDGRHPADEILQASLRAIHAALS 237
                QE+     ++    A + E        +D   P + +L A   A+ +A++
Sbjct: 154 PDRFEQERDGFFERVHEGYAALAERFPERIRRVDAGQPLEAVLTALEEALASAVT 208


>UniRef50_Q6L016 Probable thymidylate kinase n=1 Tax=Picrophilus torridus
           RepID=KTHY_PICTO
          Length = 202

 Score = 49.3 bits (116), Expect = 9e-05,   Method: Composition-based stats.
 Identities = 36/235 (15%), Positives = 78/235 (33%), Gaps = 54/235 (22%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            IAI G DGSGK+TL   +                  +   G ++++ P        Y+ 
Sbjct: 8   FIAIEGIDGSGKTTLAGDI------------------ASYTGFYLTREP-TDRFCYDYIE 48

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           +                  +  +L +  R    +++      G  +I+DRY         
Sbjct: 49  ADYNDESS----------IINFFLFTLDRYMHQKEIKNHLING--VISDRY---VFSSIA 93

Query: 136 FDGPQLAKTT-GGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-------- 186
           + G  + K     +  I  +      +       +P L+I L ID   A  R        
Sbjct: 94  YQGSGMEKRFKNMDETISWMLDVSRFI------IMPDLIIYLKIDPGIALKRLNLRKNEK 147

Query: 187 -KPDH-QLAALQEKIAVTPQLTFNG---AKILELDGRHPADEILQASLRAIHAAL 236
              D  +   + + ++      F+G     +++++     + +   +++ ++  L
Sbjct: 148 KNTDAFERLEMLKNVSKYYDYIFSGIIKIPVIKINAEMEYNYVKDEAIKGLNDYL 202


>UniRef50_Q0WW55 Thymidylate kinase-like protein n=22 Tax=Eukaryota
           RepID=Q0WW55_ARATH
          Length = 263

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 46/222 (20%), Positives = 77/222 (34%), Gaps = 43/222 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I + G D SGKST  A L++ L          LG  +     +  +   +G     YL 
Sbjct: 61  LIVLEGLDRSGKSTQCAKLLSFLNG--------LGHPTELW-RFPDRETSVGQMISAYLS 111

Query: 76  SKAA-HVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           +K+    H             +  L S  R  K   M  K + G  LI DRY        
Sbjct: 112 NKSQLDDHT------------IHLLFSANRWEKRSLMEEKLKTGTTLIVDRY-------- 151

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK--PDHQL 192
            + G   +        I+  +  E+ L        P  ++ L I  + A  R    D + 
Sbjct: 152 SYSGVAFSSA--KGLDIEWCKAPEIGL------LAPDSVLYLDISPERAAERGGYGDERY 203

Query: 193 A--ALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAI 232
                Q+K+A   Q T   +    ++     +E+ +   + +
Sbjct: 204 ERVEFQKKVADFYQ-TLGDSSWKIINASDAMEEVEKKIQQVV 244


>UniRef50_A3V698 Glycosyltransferase, group 1 n=1 Tax=Loktanella vestfoldensis SKA53
           RepID=A3V698_9RHOB
          Length = 632

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 40/196 (20%), Positives = 67/196 (34%), Gaps = 37/196 (18%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMP-TEHIYLGQSS---------------GRIGE 58
           R++ I+G DGSGK+TL+ +LV  L  R      ++LG  S                R G+
Sbjct: 3   RLVCIIGTDGSGKTTLSDALVERLQGRGERARRVWLGSESYLMAPVRAALKLVWDRRRGK 62

Query: 59  WISQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCW--RAYKFRKMLCKSQ 116
             S  P  G          AA + +K +    +  A+ +YL   W     +        +
Sbjct: 63  GKSHGPKPG--LASQRVDYAAEIAQKNALAARHPFAVRVYLAMVWFDYWLQLWIKRLGLR 120

Query: 117 QGFLLITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYL---PVLL 173
               ++ DRY                        +      E+  Y          P + 
Sbjct: 121 DAGTIVADRY-------------LFDVAVNVGLALGW-SPEEVVRYAQTQICRIPLPEVR 166

Query: 174 IRLGIDEQTAFARKPD 189
           + L ++ + + ARK D
Sbjct: 167 VFLRVEPEVSMARKDD 182


>UniRef50_D2E8C8 ORF77 n=1 Tax=Anguillid herpesvirus 1 RepID=D2E8C8_9VIRU
          Length = 214

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 35/197 (17%), Positives = 60/197 (30%), Gaps = 44/197 (22%)

Query: 15  RVIAIVGCDGSGKSTLTASLVN-ELAARMPTEHIYL-GQSSGRIGEWISQLPVIGAPFGR 72
           R+IA+ GCD +GKSTL A L      +        + G  +G +     + P + +    
Sbjct: 17  RLIAVEGCDRTGKSTLCARLAETWPESITAVHFPKMEGTFTGSVLRTAFKTPFVRSN--- 73

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVP 132
                                 ++  L S  R      +  +  +G +++ DRY      
Sbjct: 74  --------------------PRIMHLLFSANRWELMDFIGAELAKGKIVVCDRYF----- 108

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK---PD 189
                G  LA +       +     + +L Q      P   I L         RK    D
Sbjct: 109 -----GSGLAYSMVKGLDQEWCEGPDRRLIQ------PDATIYLDAPLSALMKRKDWGAD 157

Query: 190 HQLAALQEKIAVTPQLT 206
                 + +  + P   
Sbjct: 158 TVFETEEFQSKLIPIYD 174


>UniRef50_A1VCE6 Thymidylate kinase n=15 Tax=Bacteria RepID=KTHY_DESVV
          Length = 224

 Score = 48.9 bits (115), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 49/239 (20%), Positives = 83/239 (34%), Gaps = 49/239 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G +GSGKST    L   L                  G  +++ P  G+  GR LR
Sbjct: 2   FITFEGIEGSGKSTALQGLAAWLQQHGH-------------GVAVTREPG-GSRLGRTLR 47

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLC-KSQQGFLLITDRYPQVEVPGF 134
           S    +     TP        ++L    RA    +++     +G ++++DRY        
Sbjct: 48  SILLDLGNTDITPEAE-----LFLYLADRAQHVAQVVRPALDEGMVVLSDRYA------- 95

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQT----AFARKPDH 190
             D   + +  G      MLRQ        +    P L I L ++ +     A AR    
Sbjct: 96  --DSTVVYQGYGRGLDPMMLRQFNDVA---VGGLWPDLTILLDLEPEAGLNRALARNIRE 150

Query: 191 ---------QLAALQEKIAVTP-QLTFN---GAKILELDGRHPADEILQASLRAIHAAL 236
                    +  +L     V    LT+    G +   +D     +++++  +  + AAL
Sbjct: 151 GMHAAEGRFEAESLAFHTRVREGYLTWAALHGGRYRVVDATQSPEDVVRDVVGIVAAAL 209


>UniRef50_A9ETA2 Putative Thymidylate kinase n=1 Tax=Sorangium cellulosum 'So ce 56'
           RepID=A9ETA2_SORC5
          Length = 208

 Score = 48.9 bits (115), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 49/229 (21%), Positives = 83/229 (36%), Gaps = 42/229 (18%)

Query: 21  GCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLRSKAAH 80
           G DG+G ST               E       + R    +++ P  G P G  LR    H
Sbjct: 5   GIDGAGTST-------------QAERFAAHLRAARRMVHVTREPSAG-PVGALLRQVLTH 50

Query: 81  VHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEVPGFRFDGP 139
               P      I AL   L S  R      ++    + G+++I+DRY   ++    +   
Sbjct: 51  RISLPGARQAEIMAL---LFSADRLDHLGAEIEPLLRDGYVVISDRY---DLSSLAYQST 104

Query: 140 QLAKTTGGNG-WIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH-QLAALQE 197
              +   G+G  ++ +R+             P + + + +  + A  R+        L E
Sbjct: 105 TAGEDGAGSGAIVEWIRELNRHAL------RPDVTVVIDVAPEIAEKRRRGRGGAEELFE 158

Query: 198 KIAVTPQLT---------FNGAKILELDGRHPADEILQASLRAIHAALS 237
           K  +  +L            G +++ +DG    DE+     RAI AALS
Sbjct: 159 KTELQARLAEAYRRAEELVPGDRVIHIDGNGSVDEV----ARAITAALS 203


>UniRef50_Q0C176 Thymidylate kinase n=1 Tax=Hyphomonas neptunium ATCC 15444
           RepID=Q0C176_HYPNA
          Length = 219

 Score = 48.9 bits (115), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 43/234 (18%), Positives = 85/234 (36%), Gaps = 44/234 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G +G+GKSTL  +L  +L A               IG  +++ P  G P     R
Sbjct: 9   FITLEGGEGTGKSTLAKALARKLEAHG-------------IGVVVTREPG-GTPLAEAAR 54

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
               H  E  +  P +   LV    +  R +  + +     +G  +I DR+         
Sbjct: 55  QLLLHPPEGEAWSPLSEALLVN---AARRDHLEKLIRPALARGDWVICDRFA-------- 103

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTA------------ 183
            D  ++ ++  G   +  L   E ++   +   +P + + L +    A            
Sbjct: 104 -DSTRVYQSIEGGVDVSALLSIEREV---LGDTVPSMTLILDVSLDVASKRRTARAGALD 159

Query: 184 -FARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
            F R+P     A++       +      ++++ D     D++L A+ + +   L
Sbjct: 160 TFERRPKAFHEAVRAAFQDIARSEPARCRLIDTDVTP--DQVLDAAWKQVATLL 211


>UniRef50_B3T390 Putative Thymidylate kinase n=1 Tax=uncultured marine crenarchaeote
           HF4000_ANIW97J3 RepID=B3T390_9ARCH
          Length = 292

 Score = 48.6 bits (114), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 37/184 (20%), Positives = 63/184 (34%), Gaps = 36/184 (19%)

Query: 4   RNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQL 63
           R + +  S  V +IAI G D +GK T T  LV  L                +I   +   
Sbjct: 90  RFLILRQSYSVLIIAIEGLDQAGKKTQTEMLVKALRRI-------------KIKTAVFSF 136

Query: 64  PVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLIT 123
           P      G+ +++  +               ++ YL +  R  K  ++   S +  +L+ 
Sbjct: 137 PDYSTIIGKEIKNHLSGKRN-------FPPEIIHYLYAANRLEKLEEIQKASSKNSVLVM 189

Query: 124 DRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTA 183
           +RY              L          K L++ E  L          L+I L   +  +
Sbjct: 190 NRYYHSN----------LVYGIANGLKEKWLQKLEEGL------PKADLVIVLDASQDDS 233

Query: 184 FARK 187
           F+RK
Sbjct: 234 FSRK 237


>UniRef50_Q28SW8 Thymidylate kinase n=39 Tax=Rhodobacterales RepID=KTHY_JANSC
          Length = 208

 Score = 48.6 bits (114), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 40/176 (22%), Positives = 66/176 (37%), Gaps = 35/176 (19%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARM--PTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           P   I++ G DGSGKST TA LV+ L  R   P +    G S G   E I +L V G P 
Sbjct: 2   PPLFISLEGIDGSGKSTQTARLVDWLRVRGRDPLQTREPGGSEG--AEEIRRLLVEGDP- 58

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVE 130
                  +A                ++   +  R +  R +      G  ++TDR+    
Sbjct: 59  ----DRWSAETE-------------ILLFTAARRDHLERTIRPALASGRDVVTDRFA--- 98

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR 186
                 D  ++ +         ++ +   +  +      P L + L +D + A +R
Sbjct: 99  ------DSTRVYQGATRGALRGLVDRIHAEAIE----AEPDLTLILDMDPELALSR 144


>UniRef50_C7DHA0 dTMP kinase n=1 Tax=Candidatus Micrarchaeum acidiphilum ARMAN-2
           RepID=C7DHA0_9EURY
          Length = 215

 Score = 48.6 bits (114), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 39/189 (20%), Positives = 64/189 (33%), Gaps = 36/189 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA  G DGSGKST    L + L +           +SG IG+ I ++ V          
Sbjct: 2   LIAFEGIDGSGKSTQAEMLDSYLKSSGIAAVTTAEPTSGPIGKLIKEIVV---------- 51

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                     S  P N  A+ +   +    +    ++    +G ++ITDRY         
Sbjct: 52  ----------SKKPINALAMQMLFTADRAYHLETTIMPSISEGKVIITDRYI-------- 93

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
             G  +A  T      + L     K         P +   +  + + A  R        L
Sbjct: 94  --GSTIAYGTAAGIDKRFLVGINRKF------IPPDITFVIDANPRKAVERLNRRAAEFL 145

Query: 196 QEKIAVTPQ 204
           + K A+  +
Sbjct: 146 KNKTALMEK 154


>UniRef50_A7VTJ2 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A7VTJ2_9CLOT
          Length = 222

 Score = 48.6 bits (114), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 36/188 (19%), Positives = 68/188 (36%), Gaps = 30/188 (15%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           ++I + G DGSGK+T T  L   L +R               G  +  +     P  R  
Sbjct: 5   KLIVMEGLDGSGKATQTGLLCQYLESR---------------GRRVRHIEF---PDYREP 46

Query: 75  RSKAAHVH--EKPSTPPGNITALVI-YLLSCWRAYKFRKMLCK-SQQGFLLITDRYPQVE 130
            S    ++  ++  + PG++ A       +  R   F +   K    G  ++ DRY    
Sbjct: 47  SSALVKMYLNKEFGSNPGDVNAYAASSFYAVDRYASFLRFWRKDYLSGATIVADRYTTSN 106

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH 190
              ++ +          N ++  L+  E   Y  +    P L++ L +  + +  R    
Sbjct: 107 -AVYQMEKT---PREDWNKYLAWLQDYE---YGKLQLPRPDLVLFLDMPTEIS-QRLLSG 158

Query: 191 QLAALQEK 198
           + A  + K
Sbjct: 159 RYAGDERK 166


>UniRef50_Q581B1 Thymidylate kinase, putative n=3 Tax=Trypanosoma brucei
           RepID=Q581B1_9TRYP
          Length = 345

 Score = 48.2 bits (113), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 38/189 (20%), Positives = 66/189 (34%), Gaps = 28/189 (14%)

Query: 10  NSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAP 69
           N++   VI   G DG+GK+T T  +   L           G++   +       P     
Sbjct: 124 NNSESAVIVFEGGDGAGKATQTEYMRKRLDKE--------GKAHASL-----DFPSDKHR 170

Query: 70  FGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQV 129
           +G+ +R     +  +          L   L S  R     ++      G  ++ DRY   
Sbjct: 171 YGKLIRKV---LSGERGALHDLDPKLFSLLFSLNRFDTLPELRYWLTHGKKILLDRYYTS 227

Query: 130 EVPGFRFDGPQLAKTTGGNG--WIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTA-FAR 186
                   G Q +K        +I+ L Q EL   +W+    P + + L +    A  A 
Sbjct: 228 NF------GHQASKLEESERSDFIRHLEQLEL---EWLKLPPPDVALYLDLPPAAALVAM 278

Query: 187 KPDHQLAAL 195
           + D +  +L
Sbjct: 279 QRDEKRESL 287


>UniRef50_A6NRP2 Putative uncharacterized protein n=2 Tax=Bacteria
           RepID=A6NRP2_9BACE
          Length = 224

 Score = 48.2 bits (113), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 33/172 (19%), Positives = 54/172 (31%), Gaps = 23/172 (13%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           ++I   G DGSGKST  A L   L          +          + ++ + G       
Sbjct: 4   KLIVFEGTDGSGKSTQFAKLCERLEQEGTDFRRLIFPQYKEPSSALLRMYLNG------- 56

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPG 133
                   E  + P            +  R   ++K      Q G L+++DRY       
Sbjct: 57  --------EFGTHPDDVNPYAASTFYAVDRYAAWKKDWGSYYQNGGLVLSDRYTTSNAVH 108

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA 185
                 +L +    N +I+ L   E      +    P L+I L +    A  
Sbjct: 109 QTC---KLPEAEWEN-FIRWLFDFECG---KLGLPAPDLVIYLDMPTDKAVE 153


>UniRef50_Q22018 Probable thymidylate kinase n=3 Tax=Caenorhabditis RepID=KTHY_CAEEL
          Length = 218

 Score = 48.2 bits (113), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 29/171 (16%), Positives = 53/171 (30%), Gaps = 27/171 (15%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I   G D SGKST    LV  +  +        G +S      +   P   +  G+ + 
Sbjct: 10  LIVFEGLDRSGKSTQAKRLVESINKKSTES----GDASSSPSAVLQAFPDRSSSIGKLID 65

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                  +            +  L S  R  K + +     +G  +I DRY         
Sbjct: 66  QYLRKEIDMDEHA-------LHLLFSADRFSKNQMIRDNIAKGIDVICDRYCYS------ 112

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR 186
                +A +       + +R  ++ L        P  ++   +  + A  R
Sbjct: 113 ----GVAYSLAKGLPEQWVRSSDVGL------PKPDAVLFFDVSPEVAAQR 153


>UniRef50_C4KZW9 Thymidylate kinase n=1 Tax=Exiguobacterium sp. AT1b
           RepID=KTHY_EXISA
          Length = 212

 Score = 48.2 bits (113), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 41/227 (18%), Positives = 81/227 (35%), Gaps = 49/227 (21%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G DGSGKST    LV  L  +                  +++ P  G   G  +R
Sbjct: 5   FITVEGPDGSGKSTQLQLLVENLKQKG-------------YDIVVTREPG-GTTVGNQIR 50

Query: 76  SK--AAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLC-KSQQGFLLITDRYPQVEVP 132
               +   HE           + + L +  RA    +++    ++G +++ DR+    + 
Sbjct: 51  EVLLSPDHHEM-------TPRVEMMLYAASRAQNVEQVIRPALERGAIVLCDRFIDASIA 103

Query: 133 ----GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMAS-YLPVLLIRLGIDEQTAFARK 187
               G ++D  Q+                   L +W  +   P L     ++ + A AR 
Sbjct: 104 YQGYGLQYDLDQI-----------------RSLNEWATNGLTPDLTFLFDLNPERASARM 146

Query: 188 PDH-QLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIH 233
            D  QL  ++ +     +  + G + L    ++P   +   + ++I 
Sbjct: 147 KDRGQLDRIESRDQAFHERVYAGFQTLL--KQYPERIVRIDADQSIE 191


>UniRef50_B5YD95 Thymidylate kinase n=1 Tax=Dictyoglomus thermophilum H-6-12
           RepID=B5YD95_DICT6
          Length = 205

 Score = 47.8 bits (112), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 36/185 (19%), Positives = 67/185 (36%), Gaps = 36/185 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSG--RIGEWISQLPVIGAPFGRY 73
            I   G DGSGK+T    L + L ++     +YL +  G   +G  I ++ +        
Sbjct: 6   FITFEGIDGSGKTTQAILLKDYLESKG--FKVYLTREPGGTEVGSKIREILL-------- 55

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
                      P       T + +YL S  R      +  K ++ +++I +RY    +  
Sbjct: 56  ----------SPDFSINPWTEVFLYLAS--RVENTIVVKKKLEENYIVICERYADSTIA- 102

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLA 193
             + G       G N  + +L +         +   P L + + +D + A  RK      
Sbjct: 103 --YQG------YGRNLPLNILAEMNDIA---TSGLKPDLTVLIDLDPELALRRKKTFDRI 151

Query: 194 ALQEK 198
            ++ K
Sbjct: 152 EMEGK 156


>UniRef50_A6LPM3 Thymidylate kinase n=175 Tax=Firmicutes RepID=KTHY_CLOB8
          Length = 213

 Score = 47.8 bits (112), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 30/238 (12%), Positives = 77/238 (32%), Gaps = 52/238 (21%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G +G+GK+T   ++ + +     TE+ +    +   G         G      +R
Sbjct: 6   FIVFEGGEGTGKTTAIDAIYDWI-----TENNFECIKTREPG---------GIKISEQIR 51

Query: 76  SK--AAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
               +    E  +     + A      +  R +   K++    QG +++ DR+    +  
Sbjct: 52  QVILSKDNKEMDAKTEALLYA------AARRQHLVEKVIPALNQGVIVLCDRFIDSSLAY 105

Query: 134 FRF-DGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQL 192
             +     + +    N +              +  Y+P + +   +D +   AR  ++  
Sbjct: 106 QGYARNLGIEEVLSINKFA-------------IGEYMPDISVLFDLDPKIGLARIANNDC 152

Query: 193 AALQEKIAVTPQLTF--------------NGAKILELDGRHPADEILQASLRAIHAAL 236
             +        +L F              N  +I+++D  +  + ++      +   +
Sbjct: 153 REVNR--LDIEKLEFHERVREGYDIVYKNNNHRIVKIDANNTKENVINQIKNILRPKI 208


>UniRef50_B0EQM5 Thymidylate kinase, putative n=2 Tax=Entamoeba RepID=B0EQM5_ENTDI
          Length = 210

 Score = 47.8 bits (112), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 37/235 (15%), Positives = 71/235 (30%), Gaps = 46/235 (19%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARM-PTEHIYLGQSSGRIGEWISQLPVIG 67
           +N+    +I + G D SGKS+    +   L  +   +        S  IG+ I +  + G
Sbjct: 1   MNTNRGLLIVLEGIDQSGKSSAAQRVCEMLEKKGIQSIKQPFPDRSTDIGKLIDEF-LHG 59

Query: 68  APFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYP 127
                                      +V  L S  R    +K+    ++G  +I DRY 
Sbjct: 60  KNL---------------------PQQVVHLLYSANRWEVAQKIKETLEKGITIICDRYA 98

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR- 186
                        +  +       +     +  L        P ++  L +  + A  R 
Sbjct: 99  FS----------GIVYSIANGLDERWCNSADSGL------PKPDIVFFLELSLEDAEQRR 142

Query: 187 ---KPDHQLAALQEKIAVTPQLTFNGAKI--LELDGRHPADEILQASLRAIHAAL 236
              K D +   ++ +  V  +       +    +D R   +E+       I   L
Sbjct: 143 KTMKTD-RYENIKFQSKVKCEYEKFKDSMKWTCIDARQSKEEVALEITSIIEQQL 196


>UniRef50_A2QUJ3 Catalytic activity: ATP + thymidine 5'-phosphate <=> ADP +
           thymidine 5'-diphosphate n=11 Tax=Eurotiomycetidae
           RepID=A2QUJ3_ASPNC
          Length = 224

 Score = 47.8 bits (112), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 39/226 (17%), Positives = 67/226 (29%), Gaps = 44/226 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I + G D +GKS+   SL  +L     +              +  +   IG     YLR
Sbjct: 13  LIVVEGLDRAGKSSQCESLHQKLQDLGHSVKYI---------RFPDRTTPIGKLIDGYLR 63

Query: 76  -SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
                  H             +  L S  R    R +      G  +I DRY        
Sbjct: 64  GQSQLDDHS------------IHLLFSANRWEIARAIEEDIAAGITVIVDRY-------- 103

Query: 135 RFDGPQLAKTT-GGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----KPD 189
            + G   +         ++     E+ L Q      P L + L I    A  R       
Sbjct: 104 SYSGAVYSAAKANPTLSLEWAWTPEIGLPQ------PDLCLFLSIAPDEAAKRGGFGAER 157

Query: 190 HQLAALQEKIAVTPQLTF---NGAKILELDGRHPADEILQASLRAI 232
           ++   +Q ++    Q  F       I  +D     + +     +++
Sbjct: 158 YENETMQSRVRELFQTIFRVQRSGDIRVIDAGRSFEAVSVDIEKSV 203


>UniRef50_C3ZEC2 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3ZEC2_BRAFL
          Length = 215

 Score = 47.4 bits (111), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 46/230 (20%), Positives = 77/230 (33%), Gaps = 55/230 (23%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I + G D SGK+T    LV  L                 +  +  +   IG+    YL 
Sbjct: 8   LIVLEGVDHSGKTTQCMKLVEALKKHG---------QKAELIRFPDRTTAIGSVINDYLG 58

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           +K   +H+          A+ + L S  R     +M     +G  LI DRY         
Sbjct: 59  NK-CELHD---------FAIHL-LFSANRWEAVPRMEKLLSEGTSLIVDRY--------A 99

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR--------- 186
           + G            ++ L+  ++ L        P L++ L +  + A  R         
Sbjct: 100 YSGVAFTAA--KGLDMRRLQHSDIGL------PRPDLVMYLTLPPEEAAKRSEYGGERYE 151

Query: 187 KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADE----ILQASLRAI 232
           + D Q   + E   V  +  +       L+     +E    ILQ +  AI
Sbjct: 152 QTDFQK-KVAENFKVLQEDDWK-----ILNANQTIEELHTHILQLAKEAI 195


>UniRef50_A3DM71 Probable thymidylate kinase n=1 Tax=Staphylothermus marinus F1
           RepID=KTHY_STAMF
          Length = 199

 Score = 47.4 bits (111), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 20/145 (13%), Positives = 46/145 (31%), Gaps = 24/145 (16%)

Query: 100 LSCWRAYKFR-KMLCKSQQGFLLITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRE 158
            +  R    R ++L   ++G+++I DRY           G  +      N +        
Sbjct: 69  YAADRLVHIRTEILPYLRRGYIVICDRYYYSSAAYQSAQGAPIEWVLEINKYA------- 121

Query: 159 LKLYQWMASYLPVLLIRLGIDEQTAFARK-------PDHQLAALQEKIAVTPQLTFNGAK 211
                      P L I L +D      R+       P+++      ++        +   
Sbjct: 122 ---------LKPDLTIYLDVDPAIGVKRRKGLNTRFPEYEKLDFLYRVRENYLWLVDKGY 172

Query: 212 ILELDGRHPADEILQASLRAIHAAL 236
           ++ +D     D++ +   + +   L
Sbjct: 173 MVLVDANREFDKVYRDVEKIVLEHL 197


>UniRef50_A9BCY7 Thymidylate kinase n=9 Tax=Prochlorococcus marinus RepID=KTHY_PROM4
          Length = 215

 Score = 47.4 bits (111), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 39/184 (21%), Positives = 71/184 (38%), Gaps = 26/184 (14%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G DG GKST  + +   L           G        +I++ P  G   G+ L 
Sbjct: 5   FIVLEGIDGCGKSTQISHISKWLPQS--------GLMPKNANLYITREPG-GTTLGKSL- 54

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKM-LCKSQQGFLLITDRYPQVEVPGF 134
            +   +HE  +  P  +T L++Y  +  RA     +   K  +G  +I+DR+    +   
Sbjct: 55  -RDLLLHEHETNVPAPLTELLLY--AADRAEHIHSLIQPKLDKGDWVISDRFSGSTLA-- 109

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
            + G       G    I ++R+ +    Q +    P + I L I   T+  R+       
Sbjct: 110 -YQG------FGRGLDINLIRRLDAIARQGLV---PEITIFLKISVLTSMRRRAKKSADR 159

Query: 195 LQEK 198
           ++ +
Sbjct: 160 MEAE 163


>UniRef50_D1PL57 dTMP kinase n=1 Tax=Subdoligranulum variabile DSM 15176
           RepID=D1PL57_9FIRM
          Length = 223

 Score = 47.4 bits (111), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 29/177 (16%), Positives = 59/177 (33%), Gaps = 37/177 (20%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           ++I   G DGSGK T TA    +L A           +       + ++ + G    +  
Sbjct: 3   KLIIFEGLDGSGKGTQTALTAQKLKAHGVDLRQITFPNYESDSSALVKMYLSGQFGDK-- 60

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQ----- 128
                + +   S              +  R   ++       + G L+++DRY       
Sbjct: 61  -PDDVNAYAASS------------FYAVDRFASYKTDWGDFYRAGGLILSDRYTTSNAVH 107

Query: 129 --VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTA 183
              ++P   +DG           ++  L   E   Y+ +    P  ++ L +D + +
Sbjct: 108 QCAKLPPMHWDG-----------FLNWLFDFE---YKKIGIPAPDAVVYLAVDPEVS 150


>UniRef50_A6S4P1 Putative uncharacterized protein n=2 Tax=Sclerotiniaceae
           RepID=A6S4P1_BOTFB
          Length = 242

 Score = 47.4 bits (111), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 40/241 (16%), Positives = 84/241 (34%), Gaps = 45/241 (18%)

Query: 9   INSTPVR---VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPV 65
           +++ P+     I I G D +GK+T    L          + +Y    + ++  +  +   
Sbjct: 13  VSADPISRGSFILIEGLDRAGKTTQVKKL---------CDKLYASGRNVKLMRFPDRTTA 63

Query: 66  IGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDR 125
           IG     YL+S  A                +  L S  R  K +++     QG+ ++ DR
Sbjct: 64  IGQQINSYLQSSTA-----------LPDQSIHLLFSANRWEKAQEIRDLIAQGYTIVCDR 112

Query: 126 YPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA 185
           Y      G  +   + +  +  +  ++  +  E+ L       +P  +I L ++ + A  
Sbjct: 113 YY---YSGMIYTSSKYSIDSPNHLSLEWCKNPEIGL------PMPDRVIFLDLEPEEAEK 163

Query: 186 RK--PDHQLA--ALQEKIA---------VTPQLTFNGAKILELDGRHPADEILQASLRAI 232
           R    D +     +Q ++            P        +  +D     DE+ +    A+
Sbjct: 164 RGGYGDEKYETREMQRRVRNGFLSLQNSAVPGFEQEQRIMKAIDAGDGLDEVAEKIWHAV 223

Query: 233 H 233
            
Sbjct: 224 K 224


>UniRef50_C6A0S1 Probable thymidylate kinase n=4 Tax=Thermococcus RepID=KTHY_THESM
          Length = 210

 Score = 47.4 bits (111), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 43/230 (18%), Positives = 77/230 (33%), Gaps = 38/230 (16%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G DG+GKST    L      R     +    +    G+ I +L +IG   G    
Sbjct: 4   FIVLEGIDGAGKSTQAKMLAKWFENRGYEVVLTKEPTDTAFGKLIRRLVLIGGKEGIIDG 63

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKS-QQGFLLITDRYPQVEVPGF 134
           ++ +   E               L +  RA   +K++  S + G ++I+DRY        
Sbjct: 64  ARISKEAEAL-------------LFAADRAEHVKKLIEPSIKAGKVVISDRYFYSS---- 106

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA-------RK 187
                 LA        +  L            +    L+I L +  + +         R 
Sbjct: 107 ------LAYQWARGLDLNWLINLNA------FAPRADLVILLDLPVKESINRINGRSIRS 154

Query: 188 PDHQLAALQEKIAVTP-QLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
              ++  LQ+K+     +L     +I  ++   P ++I       I   L
Sbjct: 155 EFDKIVELQKKVRKNYLKLAEKFNEIRIINALAPVEDIHNDITALIEHEL 204


>UniRef50_Q601T1 Thymidylate kinase n=6 Tax=Mycoplasma RepID=KTHY_MYCH2
          Length = 211

 Score = 47.0 bits (110), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 43/221 (19%), Positives = 74/221 (33%), Gaps = 38/221 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I+  G D SGKST+       L  + P + I            ++     G      L+
Sbjct: 2   FISFEGIDASGKSTVMDLFAKYLKIKFPEKEI------------VTTFEPGGKNLKEALQ 49

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
            +   + +     P     L     +  R +  R +    + G +++ DRY    +    
Sbjct: 50  IREFLLSKNNQISPYVEMLL---FATARRIHLERLIWPALKAGKIVLCDRYIDSSIA--- 103

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK---PDHQL 192
           + G       G    I ++      + +   +  P L I L I    AF R     DH  
Sbjct: 104 YQG------FGNGLDIDLVTSLNSLISE---NTFPDLTIFLDIKISKAFERMGIFRDHNR 154

Query: 193 AALQEKIAVTPQLTFNGAKIL--------ELDGRHPADEIL 225
             L+ +     +   NG + L        ++DG    DE+L
Sbjct: 155 DRLENRGVEFYEKVINGYEFLAKKNKNFFKIDGNGTYDEVL 195


>UniRef50_A5G4M6 Thymidylate synthase / thymidylate kinase n=3 Tax=Bacteria
           RepID=A5G4M6_GEOUR
          Length = 228

 Score = 47.0 bits (110), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 36/180 (20%), Positives = 57/180 (31%), Gaps = 37/180 (20%)

Query: 7   SIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVI 66
           S+    P ++IA+ G DGSGKST    L   L  R     +Y  +               
Sbjct: 4   SLTTELPGKLIAVEGLDGSGKSTQLYLLKRWLELRG--LKVYFTE--------------- 46

Query: 67  GAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRY 126
                  +  KA    +K         +L+       R    R++L   + G+L++ DRY
Sbjct: 47  --WNSSVIVKKATSKGKKRQLLTPTTFSLIHSADLADRYE--RQILPLLKAGYLVLCDRY 102

Query: 127 PQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR 186
                          A+          L      LY +  +  P L +        A +R
Sbjct: 103 VY----------TAFARDAVRGCSRTWL----RNLYGF--ARHPDLTLFFDTPLSVALSR 146


>UniRef50_C6TJ88 Putative uncharacterized protein n=1 Tax=Glycine max
           RepID=C6TJ88_SOYBN
          Length = 299

 Score = 47.0 bits (110), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 40/221 (18%), Positives = 77/221 (34%), Gaps = 41/221 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           ++ + G D SGKS+  + LV  L  +           S  +  +  +   +G     YL 
Sbjct: 60  LVVLEGLDRSGKSSQCSRLVPFLEGQG---------ISAELWRFPDRTTNVGQMISAYL- 109

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           +  + + +            +  L S  R  K   M  K + G  LI DRY         
Sbjct: 110 TNTSQLDDH----------TIHLLFSANRWEKRSLMESKLKTGTTLIVDRY--------S 151

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK--PDHQLA 193
           + G   +   G +   +  +  E+ L        P +++ L I  + A  R      +  
Sbjct: 152 YSGVAFSSAKGLDF--EWCKVPEIGL------PAPDVVVYLDISPEKAAERGGYGGERYE 203

Query: 194 AL--QEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAI 232
            L  Q+K+A       +     ++D   P +++ +     +
Sbjct: 204 KLEFQKKVAD-WYKVLHDVSWKDVDACQPIEDVEKQLQEIV 243


>UniRef50_D1YVU8 Probable thymidylate kinase n=2 Tax=Euryarchaeota
           RepID=D1YVU8_METPS
          Length = 201

 Score = 47.0 bits (110), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 38/229 (16%), Positives = 74/229 (32%), Gaps = 43/229 (18%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           R+I I G DG+GK+T    L   L             + G+ G+ I++    G+      
Sbjct: 6   RLITIEGIDGTGKTTQVQLLKEWLERHGVEAVALKEPTQGKYGQEIARRAHAGSF----- 60

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
                          G    L +  +   R    + +    + G  +I DRY    +   
Sbjct: 61  ---------------GPRDELRL-FMEDRREDVEKNIRPALESGKSVIMDRYY---LSNM 101

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQ--- 191
            + G +               + E + +    S +P L+I L +  + + AR    +   
Sbjct: 102 AYQGARGLDPER--------IRLENEAF----SPVPDLIIILDLAPEKSMARVNTRKNVV 149

Query: 192 ----LAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                 A  EK+             + ++   P  ++ +  + A+   L
Sbjct: 150 GHFENEAYLEKVRKIFLAIGKQPNAVVINTEAPVADVHERIVDAVRDRL 198


>UniRef50_B6QFH6 Thymidylate kinase n=13 Tax=Eurotiomycetidae RepID=B6QFH6_PENMQ
          Length = 238

 Score = 47.0 bits (110), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 41/226 (18%), Positives = 71/226 (31%), Gaps = 44/226 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           ++ + G D +GKS+    L   L          LG           + P    P G+ + 
Sbjct: 15  LVVVEGLDRAGKSSQCELLYKSL----------LGM---NYKAKYIRFPDRSTPIGKQID 61

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
              +++  +      +I  L     S  R    + +      G  +I DRY         
Sbjct: 62  ---SYLRGESQLDDHSIHLL----FSANRWEVAQSIQKDIADGTTVIVDRY--------S 106

Query: 136 FDGPQLAKTTGG-NGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-------- 186
           + G   +   G  N  +    Q E+ L        P L + L I  + A  R        
Sbjct: 107 YSGAVYSAAKGNPNLSLHWAWQPEVGL------PRPDLCLFLSISPEEAAKRGGYGVERY 160

Query: 187 KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAI 232
           + D     +++       L  N  +I  +D     DE+    L  +
Sbjct: 161 ETDSMQKRVRDLFLSLLDLPHND-EICVIDAGQSVDEVALDILEPV 205


>UniRef50_Q46DH6 Probable thymidylate kinase n=4 Tax=Methanosarcinaceae
           RepID=KTHY_METBF
          Length = 205

 Score = 46.6 bits (109), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 41/234 (17%), Positives = 82/234 (35%), Gaps = 45/234 (19%)

Query: 15  RVIAIVGCDGSGKSTLTASLVN--ELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
           ++I + G DGSGKST+   L    E+ A  P                 ++  + G    +
Sbjct: 4   KLITLEGIDGSGKSTVAEKLQKNPEIKAFKPV-----------FTREPTRGTLTGDAVEK 52

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLC-KSQQGFLLITDRYPQVEV 131
            ++S      E             ++L +   A    K++    + G ++I+DRY     
Sbjct: 53  AIQSDTDQFAE-------------LFLFTADHAEHLAKLIKPALENGKIVISDRYSDSR- 98

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----- 186
             + + G  L         ++ ++        W  + +P L     I  + +  R     
Sbjct: 99  --YAYQGITLKTRLENP--LEWVKDLHRS---W--TIVPDLTFLFDIRPEISIERCGKRG 149

Query: 187 --KPDHQLAALQEKIAVTPQLTFNG-AKILELDGRHPADEILQASLRAIHAALS 237
                 +L  LQ   A+  +L  +   + + +D     + I +  ++ I   LS
Sbjct: 150 EQSKFEKLEFLQGVRAIFLKLAADDPERFVVIDASRSPEYIEKEVVKKILEFLS 203


>UniRef50_A9DXA8 Thymidylate kinase n=1 Tax=Kordia algicida OT-1 RepID=A9DXA8_9FLAO
          Length = 206

 Score = 46.6 bits (109), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 38/177 (21%), Positives = 59/177 (33%), Gaps = 43/177 (24%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            IAI G DGSGKST   ++   L A      +YL      +         IG    R + 
Sbjct: 6   FIAIEGIDGSGKSTQAKNIAKRLEAEG--HKVYLTFEPTDM--------RIGKMI-RSIL 54

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK----MLCKSQQGFLLITDRYPQVEV 131
                  EK          ++  L    R          +L K  +G+ +ITDRY     
Sbjct: 55  GGQEKADEK----------VIAALFVADRLDHILHETNGILKKLAEGYTVITDRYY---F 101

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMAS--YLPVLLIRLGIDEQTAFAR 186
             + + G  +         +  + Q        MA+    P + I + +  + A  R
Sbjct: 102 SSYAYHGAHMD--------MDWVIQS-----NKMAADILKPTVNIFVDVSPEVAMKR 145


>UniRef50_A9A2S6 Thymidylate kinase n=1 Tax=Nitrosopumilus maritimus SCM1
           RepID=A9A2S6_NITMS
          Length = 193

 Score = 46.6 bits (109), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 39/221 (17%), Positives = 70/221 (31%), Gaps = 43/221 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARM-PTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           +I I G D +GK T +  L   L  R   T+  +       IG+ I Q            
Sbjct: 2   IIVIEGGDQAGKLTQSTMLEKALKKRKIKTKLFHFPDYKTHIGKEIRQYL---------- 51

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
                   +     P     ++  LLS  R  K  ++    ++  +LI +RY        
Sbjct: 52  --------DGKRKFP---PQVIHCLLSANRWEKLEQIKTAQEKNSVLIMNRYYHSN---- 96

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD----- 189
                 L          K L   +  L          L+I L + ++ +F R+       
Sbjct: 97  ------LVYGLANGMKEKWLESLDAGL------PKADLVILLDVTQKESFNRQKTNRDKF 144

Query: 190 HQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLR 230
            +      KI+   + T    +   +D      E+ +  ++
Sbjct: 145 EKNEEFLRKISRIYKTTAKKKRWKIIDATKSKQEVHEEIMK 185


>UniRef50_A6C348 Thymidylate kinase n=1 Tax=Planctomyces maris DSM 8797
           RepID=A6C348_9PLAN
          Length = 222

 Score = 46.2 bits (108), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 44/193 (22%), Positives = 72/193 (37%), Gaps = 26/193 (13%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IAI G DGSGK T  A L     A         G  +  IG       + G   G +L 
Sbjct: 4   IIAIEGIDGSGKGTQAARLHARCQAE--------GIKTSLIGFPRYDQTLFGKSIGDFLN 55

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
            +   + E           L   L +  R      +L   +   ++I DRY    V    
Sbjct: 56  GRFGELDE-------VNPFLASLLYAGDRFESRSHILNTIETSDVVIFDRYIPSNVA--- 105

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK--PDHQLA 193
             G +L+       +I+ + Q E  +Y+     +P L + + +D    +A+K   + Q  
Sbjct: 106 HQGAKLSGAERSE-FIEWIEQIEYAIYK-----MPRLNLAILLDLPADYAQKLIAEKQAR 159

Query: 194 ALQEKIAVTPQLT 206
           +  EK+A   +  
Sbjct: 160 SYTEKVADLQEAD 172


>UniRef50_B6YSZ4 Probable thymidylate kinase n=5 Tax=Thermococcaceae
           RepID=KTHY_THEON
          Length = 205

 Score = 46.2 bits (108), Expect = 9e-04,   Method: Composition-based stats.
 Identities = 39/193 (20%), Positives = 68/193 (35%), Gaps = 37/193 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I I G DG+GKST    L      +     +    +    G+ I +L + G   G    
Sbjct: 2   FIVIEGIDGAGKSTQARLLAEWFKKKGYDVVLTKEPTDTAFGKLIRRLVLTGGKEGIIDG 61

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLC-KSQQGFLLITDRYPQVEVPGF 134
           ++ +H  E               L +  RA    K++    + G ++I+DRY        
Sbjct: 62  ARISHEAEAL-------------LFAADRAEHVHKLIKPSLKTGKIVISDRYFYSS---- 104

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR------KP 188
                 LA        ++ L            +  P L+I L +  + +  R      K 
Sbjct: 105 ------LAYQWARGLDLEWLIDLNR------FAVRPDLVILLDLPVKESMKRINGRSIKT 152

Query: 189 D-HQLAALQEKIA 200
           +  ++A LQ+K+ 
Sbjct: 153 EFDKIAELQKKVR 165


>UniRef50_Q45RR2 Deoxythymidylate kinase n=1 Tax=Cyprinid herpesvirus 3
           RepID=Q45RR2_9VIRU
          Length = 233

 Score = 46.2 bits (108), Expect = 0.001,   Method: Composition-based stats.
 Identities = 45/225 (20%), Positives = 80/225 (35%), Gaps = 47/225 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I + G D SGKST    LV  L        + +G  +  +  +  +   IG     YL 
Sbjct: 23  LIILEGVDRSGKSTQCRMLVKAL--------LEMGVEA-ELMRFPDRTTPIGQMINSYLL 73

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           +K+  + +           +V  L S  R      +  K  +G  ++ DRY         
Sbjct: 74  NKS-DLDDH----------VVHLLFSANRWEAASDLKRKLMKGTTIVLDRY--------A 114

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK--PDHQLA 193
           F G        G   ++  ++ ++ L        P L++ L I+     +R    D +  
Sbjct: 115 FSGVAFTAAKPG-FELEWCKRTDVGL------PKPDLVVFLAIEASAVESRGGFGDERYE 167

Query: 194 ------ALQEKIAV-TPQLTFNGAKILELDGRHPADEILQASLRA 231
                 A++E   V    +T N  K   +D     +++    LR 
Sbjct: 168 VSAFQAAVRENFEVLMKDVTVNWRK---VDAARTPEQVHGDILRL 209


>UniRef50_D1S998 Thymidylate kinase n=1 Tax=Micromonospora aurantiaca ATCC 27029
           RepID=D1S998_9ACTO
          Length = 718

 Score = 46.2 bits (108), Expect = 0.001,   Method: Composition-based stats.
 Identities = 44/230 (19%), Positives = 82/230 (35%), Gaps = 44/230 (19%)

Query: 21  GCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLRSKAAH 80
           G +G+GKST  A L   L            ++ GR    +++ P    P G  +  ++  
Sbjct: 485 GGEGAGKSTQLAELAERL------------RAQGRD-VVVTREPG-ATPVGERI--RSLV 528

Query: 81  VHEKPSTPPGNITALVIYLLSCWRAYKFRKMLC-KSQQGFLLITDRYPQVEVPGFRFDGP 139
           +   P   P      ++Y  +  RA+    ++     +G ++I+DRY    +    + G 
Sbjct: 529 LGTTPGEAPSPRAEALLY--AADRAHHVATVVRPALVRGAVVISDRYVDSSLA---YQGA 583

Query: 140 QLAKTTGGNGWIKMLRQRELKLYQW-MASYLPVLLIRLGIDEQTAFARKPDH-------Q 191
                      +  L         W      P L++ L ++ +T  +R  D        +
Sbjct: 584 GRTLPVDE---VSWLSS-------WATGGLKPDLVVLLDVEPRTGLSRVEDRAEGTDRLE 633

Query: 192 LAAL----QEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
             +L    + + A       +  + L LD   P DE   A  R +   L+
Sbjct: 634 AESLTFHERVRYAFLDLAAGDPKRYLVLDASRPIDETADAVARRVGELLA 683


>UniRef50_A8LHM2 Thymidylate kinase n=8 Tax=Actinomycetales RepID=A8LHM2_FRASN
          Length = 241

 Score = 46.2 bits (108), Expect = 0.001,   Method: Composition-based stats.
 Identities = 34/169 (20%), Positives = 64/169 (37%), Gaps = 25/169 (14%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTE--HIYLGQSSGRIGEWISQLPVIGAPFGRY 73
           ++AI G DG+GK+TLT+ LV  + A   T     +   ++G +G  +  +          
Sbjct: 32  IVAIEGVDGAGKNTLTSRLVEAVTATGRTAGTFAFPRYAAGPLGTAVRAML--------- 82

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
                    E+ +   G+  A  + L +  RA    ++        +LI DRY       
Sbjct: 83  ------DGDERLAGLAGSARATAL-LFALDRANALPELARCVAAYDVLIVDRYLG---SN 132

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQT 182
             +   +L        ++  + + EL     +    P L + L +  +T
Sbjct: 133 AAYGAARLPAPERAE-FLDWIAELELT---RLGLPRPDLQVLLDVPVET 177


>UniRef50_Q4P9K7 Putative uncharacterized protein n=2 Tax=Fungi/Metazoa group
           RepID=Q4P9K7_USTMA
          Length = 1208

 Score = 46.2 bits (108), Expect = 0.001,   Method: Composition-based stats.
 Identities = 41/227 (18%), Positives = 69/227 (30%), Gaps = 50/227 (22%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G D +GKST    L   L A                     + P      G+ + 
Sbjct: 428 FIVVEGLDRAGKSTQVERLAAHLQA------------------KAVKFPERTTAIGQMIN 469

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           S  A   +            +  L S  R      +    + G  ++ DRY         
Sbjct: 470 SYLAQTSDLDDQA-------IHLLFSANRWECVASLHRTLEAGESIVCDRYAFS------ 516

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR--------- 186
                +A +          R  ++ L       LP L + L +D   A AR         
Sbjct: 517 ----GIAYSVAKGLSYDWCRNPDVGL------PLPDLTLFLDLDANAAAARGGYGEERYE 566

Query: 187 KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIH 233
           K D Q    +    V+  +  +G + + +D     D++     +A+H
Sbjct: 567 KLDFQAKVREAFTRVSQDVRTHGGRWVTIDASKTLDQVTDDMQKAVH 613


>UniRef50_D1BLN7 Thymidylate kinase n=15 Tax=Bacteria RepID=D1BLN7_VEIPT
          Length = 228

 Score = 45.9 bits (107), Expect = 0.001,   Method: Composition-based stats.
 Identities = 34/173 (19%), Positives = 57/173 (32%), Gaps = 26/173 (15%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I + G DGSGK+T T  LV  L              S    +  + +P        YL 
Sbjct: 4   LIILEGGDGSGKATQTKLLVERLTKEGHAVK----SVSFPNYDSGAAMP-----IKMYLA 54

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQVEV--P 132
            +      K         A  +Y +   R   FR       + G ++I DRY    +   
Sbjct: 55  GE----FGKDVHDVNPYVASSMYAI--DRFASFRTDWEQFYKNGGIIIADRYTTSNMVHQ 108

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA 185
             ++D      +     ++  L   E   +Q      P  +  L +  + + A
Sbjct: 109 MVKYD-----DSKERTAFLDWLEDFE---FQKFGLPKPDAVCLLDMPLEVSEA 153


>UniRef50_A4RZW8 Predicted protein n=13 Tax=Eukaryota RepID=A4RZW8_OSTLU
          Length = 218

 Score = 45.9 bits (107), Expect = 0.001,   Method: Composition-based stats.
 Identities = 47/226 (20%), Positives = 75/226 (33%), Gaps = 52/226 (23%)

Query: 21  GCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLRSKAAH 80
           G D  GKST    LV+ L AR              +  +  +   +G    +YLRSK+  
Sbjct: 18  GADRCGKSTQAMRLVHTLEARG---------VEAELWRYPDRATAMGKMIDQYLRSKS-- 66

Query: 81  VHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFRFDGPQ 140
                    G I  L     +  R  K   M  K   G  L+ DRY         + G  
Sbjct: 67  -----EMEDGAIHLL----FAANRWEKKALMERKLASGVTLVCDRY--------SYSGCA 109

Query: 141 LAKTTGGNGW-IKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR--------KPDHQ 191
                G +G  ++  R  E+ L        P  L+ L +  + A  R        +    
Sbjct: 110 FTAAKGVDGLDLEWCRAPEVGL------PRPDALMYLELSLEDAAKRGGFGEERYETTEM 163

Query: 192 LAALQEKIAVTPQLTFNGAKILELDGRHP----ADEILQASLRAIH 233
             A++       +  ++      +D         DE+L+ +L A+ 
Sbjct: 164 QRAVKASFEAMREDWWD-----VIDANREPDVIQDEVLRIALSAVE 204


>UniRef50_C6HZ31 Thymidylate kinase n=1 Tax=Leptospirillum ferrodiazotrophum
           RepID=C6HZ31_9BACT
          Length = 220

 Score = 45.9 bits (107), Expect = 0.001,   Method: Composition-based stats.
 Identities = 33/177 (18%), Positives = 58/177 (32%), Gaps = 37/177 (20%)

Query: 10  NSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAP 69
           +S P R+I + G DGSGKST    L + L ++        G             P+I   
Sbjct: 7   HSYPGRLIVVEGIDGSGKSTQLDLLSDYLQSKG------FGVLKSAWNSSPDISPII--- 57

Query: 70  FGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQV 129
                        +K    P   + L     S    Y+    +   + G ++++DRY   
Sbjct: 58  ---------RKAKKKQVLTPYAFSLLHAADFSFRYTYEILPAM---EAGMIVLSDRYIY- 104

Query: 130 EVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR 186
                      +A+          L         +  + +P L     +D +T++ R
Sbjct: 105 ---------TAIARDCARGLPRPWLLS------NFNFAIVPDLTFLFRVDPETSYQR 146


>UniRef50_Q254L6 Thymidylate kinase n=13 Tax=Chlamydiaceae RepID=KTHY_CHLFF
          Length = 207

 Score = 45.1 bits (105), Expect = 0.002,   Method: Composition-based stats.
 Identities = 52/232 (22%), Positives = 83/232 (35%), Gaps = 50/232 (21%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I I GC+GSGKS+LT  L N L     +       ++   G         G+P G  +R
Sbjct: 2   FIVIEGCEGSGKSSLTELLKNRLITEGKSV-----IATREPG---------GSPLGEQVR 47

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQVEVPGF 134
           +          + PG      ++L    RA     K++   + G ++I DR+    +   
Sbjct: 48  N-----WILNPSLPGISPYTELFLFLASRAQHITEKIIPALESGKIVICDRFHDSTI--- 99

Query: 135 RFDG--PQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQL 192
            + G    L K    N    ++ +++         +LP L   L I   T   RK   + 
Sbjct: 100 VYQGIAEGLGKEYVTNLCHHVVGEKK---------FLPDLTCLLDIPVDTGIKRKQQQKS 150

Query: 193 AALQEKIAVTPQLTFNGAK-------------ILELDGRHPADEILQASLRA 231
               +K    P +  N  +              L LDGR P +  L   + A
Sbjct: 151 L---DKFEDKPLVYHNKIREGFLSLAEANPENYLILDGRQPLEASLNKVMTA 199


>UniRef50_C7PHF5 Thymidylate kinase n=1 Tax=Chitinophaga pinensis DSM 2588
           RepID=C7PHF5_CHIPD
          Length = 228

 Score = 45.1 bits (105), Expect = 0.002,   Method: Composition-based stats.
 Identities = 38/177 (21%), Positives = 61/177 (34%), Gaps = 26/177 (14%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARM-PTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
           R IAI G DG+GKST    L      +   T  ++           I Q  V G    ++
Sbjct: 6   RFIAIEGLDGAGKSTQINLLQQFFNQQGIETRFVHF---------PIVQEGVFGEMIAKF 56

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           LR +   V +           LV  L +  R      +      G++++ DRY    +  
Sbjct: 57  LRGEFGDVKD-------VHPQLVALLFAEDRKAFSHTINEWLASGYVVLVDRYVLSNIA- 108

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGI---DEQTAFARK 187
             F   +L            +   E   Y++     P L + L +     + A AR+
Sbjct: 109 --FQCAKLKTDKEKQELRDWINMFE---YEYNRIPQPDLSVYLDVPFSHTEQALARR 160


>UniRef50_D2MMU9 dTMP kinase n=1 Tax=Bulleidia extructa W1219 RepID=D2MMU9_9FIRM
          Length = 225

 Score = 45.1 bits (105), Expect = 0.002,   Method: Composition-based stats.
 Identities = 43/226 (19%), Positives = 78/226 (34%), Gaps = 45/226 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I I G DGSGKST++ ++   L        + L +  G            G+     +R
Sbjct: 21  FITIEGPDGSGKSTVSQTVCQRLQQEG--YRLQLTREPG------------GSKIAEQIR 66

Query: 76  SKAAHVH--EKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           S        +  +     + A      +  R +   K+L   + G  +I+DR+    +  
Sbjct: 67  SIILDPQNTDMDARTEALLYA------ASRRQHLMDKVLPALENGIPVISDRFVDSSLA- 119

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR--KPDHQ 191
             + G               L          +   LP   I L ID +T   R  K  +Q
Sbjct: 120 --YQGVGRCIGIEP----VWLINEFA-----IEGCLPDKTIYLDIDAETGLRRIQKGRNQ 168

Query: 192 LAALQEKIAVTPQLTFNGAK---------ILELDGRHPADEILQAS 228
           L  L ++ A      F G +          +++D R   +++++ +
Sbjct: 169 LDRLDQEEASFHTRVFQGYQTILKRFPDRFIKVDARQGLEKVVEDT 214


>UniRef50_A8W246 Peptide chain release factor 2 n=1 Tax=Bacillus selenitireducens
           MLS10 RepID=A8W246_9BACI
          Length = 410

 Score = 45.1 bits (105), Expect = 0.002,   Method: Composition-based stats.
 Identities = 37/181 (20%), Positives = 69/181 (38%), Gaps = 42/181 (23%)

Query: 17  IAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLRS 76
           + ++G DG+GKS+L  ++  E+  +  T+ IYLG  +G  G  + Q+  +   F   +  
Sbjct: 215 VLVLGTDGTGKSSLIKNIRKEIPVK--TKSIYLG--TGEDGWELKQVKKMNKNFQGPILG 270

Query: 77  KAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFRF 136
           +       P                C R  +  K+  K +   L++ DR+P         
Sbjct: 271 RLLKTIILPIEF-------------CLRVIR-GKVNAKYK---LILIDRFP--------- 304

Query: 137 DGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAALQ 196
                       GW  + + +       +    P L+I L  D Q  F RK +  + ++ 
Sbjct: 305 ------------GWAIISKNKLRNYIYKIILPKPDLVIFLHGDPQILFERKKERSVESIS 352

Query: 197 E 197
           +
Sbjct: 353 K 353


>UniRef50_Q93UI7 TMP kinase n=10 Tax=Candidatus Phytoplasma RepID=Q93UI7_LOWBP
          Length = 209

 Score = 45.1 bits (105), Expect = 0.002,   Method: Composition-based stats.
 Identities = 47/191 (24%), Positives = 70/191 (36%), Gaps = 34/191 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
           +++I   G DGSGK+TL   L  +L  +     IY G  S  IG  I  L         +
Sbjct: 1   MKLIVFEGLDGSGKTTLIQELQQKLKKQKINNKIYQGLGSSSIGTEIRNL---------F 51

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCK--SQQGFLLITDRYPQVEV 131
           L                    +  + LS     + +K L     +Q  L+I DR+     
Sbjct: 52  LNYNQVDY-------------ITRFYLSITNMAQIQKELIYPHLKQNQLIILDRWLPSTY 98

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK---P 188
               F  P L +T       ++      KL+       P LLI L I+      RK    
Sbjct: 99  AYQLF--PYLKQTKSCFDLKELFDITHKKLF-----IQPHLLIYLDINPLIGKERKQTQK 151

Query: 189 DHQLAALQEKI 199
           +HQL  +++K 
Sbjct: 152 NHQLDIIEQKS 162


>UniRef50_A9BG59 Thymidylate kinase n=11 Tax=Bacteria RepID=A9BG59_PETMO
          Length = 232

 Score = 45.1 bits (105), Expect = 0.002,   Method: Composition-based stats.
 Identities = 19/104 (18%), Positives = 38/104 (36%), Gaps = 9/104 (8%)

Query: 98  YLLSCWRAYKFRKMLC-KSQQGFLLITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQ 156
              +  R   ++K L    + G +LI+DRY         +   +    +  + +++ L  
Sbjct: 74  TFFAVDRFATYQKELKPLYESGGILISDRY---TTSNMIYQSSKFENQSEKDEFLEWLWD 130

Query: 157 RELKLYQWMASYLPVLLIRLGIDEQTAFA--RKPDHQLAALQEK 198
            E   +       P  +I L I  + +    RK   ++  L  K
Sbjct: 131 LE---FNKFNLPKPNYVIFLDIPPKISIELLRKRKEKIIDLTGK 171


>UniRef50_O67099 Thymidylate kinase n=2 Tax=Aquificaceae RepID=KTHY_AQUAE
          Length = 195

 Score = 44.7 bits (104), Expect = 0.002,   Method: Composition-based stats.
 Identities = 35/225 (15%), Positives = 74/225 (32%), Gaps = 37/225 (16%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA  G DGSGK+T    L   L  +     +Y      ++GE + ++ +          
Sbjct: 2   LIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILL---------- 51

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                  ++ +         ++   +        K++   ++  ++I DR+    +    
Sbjct: 52  ---TEELDERTE--------LLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQG 100

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD----HQ 191
           + G  L      N  +     R            P + + L I    A  R  +      
Sbjct: 101 Y-GKGLDVEFIKN--LNEFATR---------GVKPDITLLLDIPVDIALRRLKEKNRFEN 148

Query: 192 LAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
              L++      +L      ++ +D     +E+ +  LRA+   L
Sbjct: 149 KEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVL 193


>UniRef50_A3EQU8 Thymidylate kinase n=2 Tax=Leptospirillum sp. Group II
           RepID=A3EQU8_9BACT
          Length = 217

 Score = 44.7 bits (104), Expect = 0.002,   Method: Composition-based stats.
 Identities = 42/233 (18%), Positives = 71/233 (30%), Gaps = 29/233 (12%)

Query: 10  NSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAP 69
           +S P R+I + G DGSGKST    L N L  +        G             P+I   
Sbjct: 4   HSFPGRLIVVEGIDGSGKSTQIELLENYLRIKG------FGVLRNAWNSSQEISPII--- 54

Query: 70  FGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQV 129
                        +K    P   + L     S    ++    L     G ++++DRY   
Sbjct: 55  ---------KKAKKKQLLTPYGFSLLHAADFSYRYTHEILPAL---NAGKIVLSDRYIYT 102

Query: 130 EVPGFRFDG-PQLAKTTGGNGWIK-----MLRQRELKLYQWMASYLPVLLIRLGIDEQTA 183
            +      G P+          I+       R      Y  +     +     G+D + +
Sbjct: 103 AIARDAARGIPRDWLVNNFRFAIRPDLTFFFRMDPALAYDRITQVRDIKYYEAGLDMELS 162

Query: 184 FARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
               P       Q ++    +          LDG  P +E  +   R ++  +
Sbjct: 163 M--NPRESYILFQSRVLEGYENLAKEHGFSVLDGAKPVEETQRVVRRLVNPLI 213


>UniRef50_B2GAE1 Thymidylate kinase n=32 Tax=Lactobacillales RepID=KTHY_LACF3
          Length = 214

 Score = 44.7 bits (104), Expect = 0.002,   Method: Composition-based stats.
 Identities = 46/233 (19%), Positives = 87/233 (37%), Gaps = 43/233 (18%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           R I+  G DG+GK+++  ++   L  ++  + +Y  +  G              P    +
Sbjct: 4   RFISFEGPDGAGKTSVLTAIRTGLVNQLGDQVVYTREPGGN-------------PIAEQV 50

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           R   A + +K +    + T  ++Y  S  R +    +    + G L++ DRY    +   
Sbjct: 51  R---AVLLDKQNGAMDDWTEALLYAAS-RRQHVVETLKPALEAGKLILCDRYLDSSI--- 103

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-------- 186
                      GG   + + R  EL  Y  +   LP L I L +  +T  AR        
Sbjct: 104 --------AYQGGGRELGIDRIWELNQYA-IDGLLPDLTIFLDLPVETGLARIEKGRAET 154

Query: 187 --KPDHQLAALQEKIAVTPQLTFNG---AKILELDGRHPADEILQASLRAIHA 234
             + D Q      ++     LT       +I++++       +++    AIHA
Sbjct: 155 INRLDEQTTNFHRRVRQAY-LTLAERFPERIVKVNADQELARVIEDVRSAIHA 206


>UniRef50_Q970Q8 Probable thymidylate kinase n=12 Tax=Sulfolobaceae
           RepID=KTHY2_SULTO
          Length = 213

 Score = 44.7 bits (104), Expect = 0.003,   Method: Composition-based stats.
 Identities = 30/170 (17%), Positives = 57/170 (33%), Gaps = 38/170 (22%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA  G DGSGKS+    L + +  +      YL + +                    ++
Sbjct: 6   LIAFEGIDGSGKSSQATLLKDWIELKRDV---YLTEWNSSD------------WIHDIIK 50

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                  +K    P   + +     S  R  ++  +L   + GF++I+DRY         
Sbjct: 51  ----EAKKKDLLTPLTFSLIHATDFS-DRYERY--ILPMLKSGFIVISDRYIY------- 96

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA 185
                 A+ +     I  +     KLY +  +  P +   + +    A  
Sbjct: 97  ---TAYARDSVRGVDIDWV----KKLYSF--AIKPDITFYIRVSPDIALE 137


>UniRef50_Q2FS90 Probable thymidylate kinase n=4 Tax=Methanomicrobiales
           RepID=KTHY_METHJ
          Length = 206

 Score = 44.3 bits (103), Expect = 0.003,   Method: Composition-based stats.
 Identities = 44/227 (19%), Positives = 74/227 (32%), Gaps = 44/227 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           ++ I G DGSGKSTL  +L   LA   P      G                    G  +R
Sbjct: 2   LVTIEGIDGSGKSTLHKALGPYLADLNPVITCEPG----------------STWIGEAVR 45

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLC-KSQQGFLLITDRYPQVEVPGF 134
                  +  +            L     A   R+++     +  L+I+DRY    +   
Sbjct: 46  RAIREHADPIAEA---------LLFVADHAAHLREVVRPALSEDRLVISDRYIDSRLVYQ 96

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-----KPD 189
           +     +            L     +      + +P L I L +    A  R       +
Sbjct: 97  QVTLDGIIPDPR-----TWL-----RAVHQGWTIMPDLTILLAVPVPVALERTGKRGSGE 146

Query: 190 H-QLAALQEKIAV--TPQLTFNGAKILELDGRHPADEILQASLRAIH 233
           H +  ++  K+       +  + A+ L LDG  P + IL+ +  AI 
Sbjct: 147 HFEQESVLTKVQEYYMQLVEEDTARFLILDGTLPPEHILKVAGEAIR 193


>UniRef50_Q1PY20 Similar to thymidylate kinase n=1 Tax=Candidatus Kuenenia
           stuttgartiensis RepID=Q1PY20_9BACT
          Length = 234

 Score = 44.3 bits (103), Expect = 0.003,   Method: Composition-based stats.
 Identities = 34/171 (19%), Positives = 59/171 (34%), Gaps = 23/171 (13%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARM-PTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
           ++I I G DGSGK+  T  L   L     P   I                P  G  F   
Sbjct: 12  KLIVITGIDGSGKTVQTKLLYERLLKEGYPVATI--------------DFPQYGKTFFAE 57

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           + +K  ++             L   L +  R  K  ++      G ++I++RY    +  
Sbjct: 58  MVAK--YLRGSFGAADAVSPYLASILYAGDRFEKKDQIQTWIDAGKIIISNRYVCDNMA- 114

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF 184
               G ++  +     + + L Q E  ++       P L I L +  + A+
Sbjct: 115 --HQGGKIKNSEERAQFFQWLDQLEHTVF---GIPRPHLSILLYVPAEIAY 160


>UniRef50_A8MB58 Probable thymidylate kinase n=3 Tax=Thermoproteaceae
           RepID=KTHY_CALMQ
          Length = 205

 Score = 44.3 bits (103), Expect = 0.003,   Method: Composition-based stats.
 Identities = 38/226 (16%), Positives = 81/226 (35%), Gaps = 44/226 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            + + G DG GKST+     +EL  R      YL  ++    +         +P G ++R
Sbjct: 4   FVDVEGIDGVGKSTVIRLTADELRRRG-----YLVYTTSEPSD---------SPIGLFIR 49

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLC-KSQQGFLLITDRYPQVEVPGF 134
              + +       P  +  L     +  R   + +++  K ++G+++IT+RY +  V   
Sbjct: 50  R--SILESNLEVEPMALALL----FAADRVIHYNRVIKPKVKEGYIVITERYIESSVA-- 101

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
            + G Q          ++ + +             P L+I L     T  +R  +  +  
Sbjct: 102 -YQGSQGVP-------VEWIIEVNS------MVAEPDLVIVLNAPLNTVASRLSNRGMLE 147

Query: 195 LQEK----IAVTPQLTFNGAK---ILELDGRHPADEILQASLRAIH 233
             E+    +    ++    A+      +D     + ++   L  I 
Sbjct: 148 YFERNTDFLRSVQEVYLRRARERNYPVIDASRVINNVVNDVLTLIE 193


>UniRef50_B4S1N2 Thymidylate kinase n=4 Tax=Alteromonadales RepID=KTHY_ALTMD
          Length = 222

 Score = 44.3 bits (103), Expect = 0.004,   Method: Composition-based stats.
 Identities = 35/232 (15%), Positives = 74/232 (31%), Gaps = 39/232 (16%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           + I + G +G+GKS++   +V  L        +   +  G            G P    +
Sbjct: 4   KFIVVEGLEGAGKSSVIGLIVKALTDAG--MRVEQTREPG------------GTPMAEAI 49

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           R    H  ++  T       L++Y  +        K+      G  ++ DR+   ++   
Sbjct: 50  RECVKHDWDE--TVSEETELLLMY--AARVQLLTNKIYPSLNAGAWVVGDRH---DLSSQ 102

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---KPDHQ 191
            + G     +      I  +          +  + P L + L +D      R   + +  
Sbjct: 103 AYQGGGRGVSEKTMTAISDIA---------LNGFKPDLTLYLDVDPAVGLERARGRGELD 153

Query: 192 LAA------LQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
                     +   A    L  N   I+ ++   P +++ Q  +  I   +S
Sbjct: 154 RIEQAGLGFFERTRARYLSLAENDESIIVVNAMQPMEQVHQDVISIIANYVS 205


>UniRef50_D2Q7V9 Thymidylate kinase n=2 Tax=Bifidobacterium dentium
           RepID=D2Q7V9_9BIFI
          Length = 252

 Score = 44.3 bits (103), Expect = 0.004,   Method: Composition-based stats.
 Identities = 36/223 (16%), Positives = 70/223 (31%), Gaps = 21/223 (9%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I+  G DG GK+T    L   + A+     +        +G  I  + + G        
Sbjct: 14  FISFEGVDGVGKTTQVERLRAHIEAQGRECVVTREPGGTALGVAIRGMLLHGVAAADAGV 73

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLC-KSQQGFLLITDRYPQVEVPGF 134
                   +   P          L +  RA    +++    ++G ++ITDRY    +   
Sbjct: 74  PANKADGGRQPEPADIAPRTEALLFAADRAQHVAEVIRPALERGAVVITDRYLDSSL--- 130

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA--RKPDHQL 192
                       G   + +   R+L L+      LP     L +D   + A  R  + ++
Sbjct: 131 --------AYQAGGRELTLKEIRDLSLWA-TNGLLPERTYLLDMDPAASHARLRHSEDRM 181

Query: 193 AALQEKIAVTPQLTF------NGAKILELDGRHPADEILQASL 229
            +  +      +  F         +   +D     +E+ Q   
Sbjct: 182 ESAGDDFQNRTRNAFLELARAEPERFRVIDASQSIEEVWQRIE 224


>UniRef50_C9SNG5 Thymidylate kinase n=7 Tax=Sordariomycetes RepID=C9SNG5_VERA1
          Length = 285

 Score = 44.3 bits (103), Expect = 0.004,   Method: Composition-based stats.
 Identities = 34/171 (19%), Positives = 60/171 (35%), Gaps = 33/171 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           ++ + G D SGK+T     V  L  R     + LG+        + + P    P G+ + 
Sbjct: 55  LVILEGLDRSGKTTQ----VKLLEQRF----VELGKK-----VKVMRFPDRSTPIGQMID 101

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           +      E           ++  L S  R    + +      G  ++ DRY      G  
Sbjct: 102 AYLKSSVEMDDH-------VIHLLFSANRWEAVKTIRQLLASGTTVLCDRYYH---SGIV 151

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR 186
           +     A     +  +   R  ++ L        P L++ L +DE TA +R
Sbjct: 152 YS----AAKHNPSLSLHWARAPDVGL------PRPDLVLFLDLDEATAKSR 192


>UniRef50_Q2RZ38 Thymidylate kinase n=2 Tax=Rhodothermaceae RepID=Q2RZ38_SALRD
          Length = 221

 Score = 43.5 bits (101), Expect = 0.006,   Method: Composition-based stats.
 Identities = 31/179 (17%), Positives = 61/179 (34%), Gaps = 30/179 (16%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           ++   G DGSGKST    L   L  R                    +  ++  P G  L 
Sbjct: 3   LLTFEGIDGSGKSTQAHRLNEHLQER------------------GHKTLLVREPGGTELS 44

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
            +   V  +P+     +  L+++  +        ++    + G ++I DR+         
Sbjct: 45  EQVRSVLLEPALNVHPMAELLLFS-AARTQLVTERIRPALEAGRIVICDRFYDSTTA--- 100

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
           + G             + L+    ++   +    P     + +D +TA AR+ +   AA
Sbjct: 101 YQGAGRNVADP-----EWLQSFHRRVTDGLV---PDRTYLVELDPETARARRTEGNDAA 151


>UniRef50_Q1C6N6 Thymidylate kinase n=40 Tax=Enterobacteriaceae RepID=KTHY_YERPA
          Length = 212

 Score = 43.5 bits (101), Expect = 0.006,   Method: Composition-based stats.
 Identities = 37/232 (15%), Positives = 75/232 (32%), Gaps = 37/232 (15%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           + I I G +G+GK+T   ++V  L A+   + ++               P+         
Sbjct: 4   KFIVIEGLEGAGKTTTRDTVVAVLRAQGINDIVF--------TREPGGTPLAEKLRDLIK 55

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           +     V    +         V+ L +         +     +G  ++ DR+   ++   
Sbjct: 56  QGIDGEVLTDKAE--------VLMLYAARVQLVENVIKPALARGSWVVGDRH---DLSSQ 104

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK------- 187
            + G       GG G    L          +  + P L + L +      AR        
Sbjct: 105 AYQG-------GGRGIDSQLMASLRDTV--LGEFRPDLTLYLDLPPAVGLARARARGELD 155

Query: 188 --PDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
                 LA  +   A   +L  + A I  +D   P +++  +  +A+   L+
Sbjct: 156 RIEQESLAFFERTRARYLELAASDASIKTIDASQPIEQVSASISQALAQWLT 207


>UniRef50_UPI0001AECAE5 thymidylate kinase n=6 Tax=Streptomyces RepID=UPI0001AECAE5
          Length = 1095

 Score = 43.2 bits (100), Expect = 0.007,   Method: Composition-based stats.
 Identities = 42/218 (19%), Positives = 79/218 (36%), Gaps = 40/218 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            IA+ G DG+GKST   +L   + A+     +     +  IG+ +  + +  +  G   R
Sbjct: 501 FIALEGGDGAGKSTQAEALAEWIRAKGHEVVVTREPGATPIGKRLRAILLDVSSAGLSHR 560

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           ++A       +     +                  +    ++G ++I+DRY    V  ++
Sbjct: 561 AEALLYAADRAEHVDTV------------------VRPALERGAVVISDRYIDSSVA-YQ 601

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---KPDH-- 190
             G  LA T       +                +P L + L +  +TA  R    PD   
Sbjct: 602 GAGRDLAPTEIA-RISRWATG----------GLVPHLTVLLDVSPETARERFTEAPDRLE 650

Query: 191 -QLAALQEKIAVTPQLTFNGA---KILELDGRHPADEI 224
            + AA  +++     LT   A   + L +D     +E+
Sbjct: 651 SEPAAFHQRVRAGF-LTLAAADQDRYLVVDAGQQPEEV 687


>UniRef50_Q1D6W4 Thymidylate kinase n=7 Tax=Cystobacterineae RepID=Q1D6W4_MYXXD
          Length = 221

 Score = 43.2 bits (100), Expect = 0.007,   Method: Composition-based stats.
 Identities = 30/175 (17%), Positives = 56/175 (32%), Gaps = 30/175 (17%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
           P R I + G DG+G +T    L   L A   +       S G +G  I Q          
Sbjct: 13  PGRFIVLEGLDGAGTTTQVERLAAALRAEGHSVLTTREPSDGPVGTMIRQ---------- 62

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVP 132
              +    +       P     L +   +    +   ++L     G +++ DRY    + 
Sbjct: 63  ---ALTGRLGLPGGAGPLAPETLALLFAADRTDHLTARVLPALAAGQIVLCDRY---VLS 116

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK 187
              + G  L         ++ +            +  P L + +G+  + A  R+
Sbjct: 117 SLAYQGASLP--------MEWVEAVNA------CAVSPDLTLFVGVAPEVAARRR 157


>UniRef50_B6BTX5 Thymidylate kinase n=1 Tax=beta proteobacterium KB13
           RepID=B6BTX5_9PROT
          Length = 201

 Score = 43.2 bits (100), Expect = 0.007,   Method: Composition-based stats.
 Identities = 38/232 (16%), Positives = 74/232 (31%), Gaps = 54/232 (23%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLP---VIGAPFGR 72
            I + G DG+GKST    + + L  +              I   +++ P    IG    +
Sbjct: 4   FITVEGIDGAGKSTHLEFIQSYLNKK-------------NIQNKLTREPGGTEIGEKLRQ 50

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVP 132
            L      V  +            + + +    +    +    Q    +I DR+      
Sbjct: 51  LLLHDDMDVGTE-----------TMMMFAARHEHLITVIQPALQSNISIICDRFTDASYA 99

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQL 192
            ++  G  + K          ++  E  ++  +    P L     +D  TA +R  + + 
Sbjct: 100 -YQQGGKGIDK--------SFVKSLEELVHPNLT---PDLTFLFDLDPDTAHSRISNERN 147

Query: 193 AALQEKIAVTPQLTFNGAKIL------------ELDGRHPADEILQASLRAI 232
               EK + T    FNG + +             +D     D+I Q   + +
Sbjct: 148 LDKFEKQSSTF---FNGVRKVYLELAKAHSRFHVIDSSQTIDQIQQVISKKL 196


>UniRef50_A0LF96 Thymidylate kinase n=1 Tax=Syntrophobacter fumaroxidans MPOB
           RepID=A0LF96_SYNFM
          Length = 222

 Score = 43.2 bits (100), Expect = 0.008,   Method: Composition-based stats.
 Identities = 41/229 (17%), Positives = 68/229 (29%), Gaps = 43/229 (18%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           + +   G DG GKSTL   L + L                 +GE I  L +   P  R +
Sbjct: 17  KFVTFEGIDGCGKSTLIDELASWLDRTRVPYVKTREPGGTSLGEKIRGLLL--DPAHRGM 74

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
             +                  V+   +         +L   + G  ++ DRY    +   
Sbjct: 75  NRQTE----------------VLLYTASRAQLVAEIILPALKSGAWVLADRYIDATLAYQ 118

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYL-PVLLIRLGIDEQTAFAR------K 187
            + G +L                  +L  W    L P   + L     TA AR      +
Sbjct: 119 GY-GRELDPDPL------------RRLQHWATQALVPDKTVLLDCGIDTAAARMSARNHR 165

Query: 188 PD-----HQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRA 231
           PD      +    + K       + +  + + LD   P  E++     A
Sbjct: 166 PDRIEMEERAFHERVKAGYLDLASLDPGRFIVLDAEKPLPEVIADFRAA 214


>UniRef50_B1I165 Thymidylate kinase n=3 Tax=Firmicutes RepID=KTHY_DESAP
          Length = 221

 Score = 43.2 bits (100), Expect = 0.009,   Method: Composition-based stats.
 Identities = 36/215 (16%), Positives = 65/215 (30%), Gaps = 31/215 (14%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G DG+GK+T  A L   L +                   +++ P  G   G  +R
Sbjct: 5   FIVFEGIDGAGKTTQLAYLHEALLSMR------------NHRVLVTREPG-GTRIGEAVR 51

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                     S   G   AL+    +    +    +     +G ++++DR+    +    
Sbjct: 52  RVLLDTGN--SEMTGETEALL--YAAARSQFTAEVVRPALARGEIVLSDRFLDSSLA--- 104

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
           + G            +  L               P L + L +    A AR    +   L
Sbjct: 105 YQGFGRGLELHRLRQVNFLAT---------GGLRPDLTVLLDLPVAAAVARMDPDRRDRL 155

Query: 196 QEKIAVTPQLTFNGAKILELDGRHPADEILQASLR 230
           + +     +    G   LEL    P   ++  + R
Sbjct: 156 EREGVDFFERVRRG--YLELASADPGHYLIVNAER 188


>UniRef50_A5FR84 Thymidylate kinase n=5 Tax=Dehalococcoides RepID=KTHY_DEHSB
          Length = 208

 Score = 42.8 bits (99), Expect = 0.009,   Method: Composition-based stats.
 Identities = 37/226 (16%), Positives = 68/226 (30%), Gaps = 39/226 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G +G GKST + +L   L  +     +       + G+ I++L            
Sbjct: 4   FITFEGGEGCGKSTQSKALYRYLKKKGLGCVLTHEPGGSKSGDKITRLL----------- 52

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                  ++    P      ++   +         +    Q G ++I DRY    +    
Sbjct: 53  ----KWSKEEHISP---LTELLLFNASRSILIDNVIKPALQDGKIVICDRYTDSTLA--- 102

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK---PDHQL 192
           + G            +  L              +P L I L +D++ A  RK   P  + 
Sbjct: 103 YQGYGRGLDLDTVKCVNSLAS---------GGLVPDLTIWLDMDDKAALLRKGELPPDRF 153

Query: 193 AALQEKIAVTPQLTFNGA------KILELDGRHPADEILQASLRAI 232
            +         +  F         + L+LD   P  EI     + +
Sbjct: 154 ESENNGFHQRVRNGFGAIYATEPDRFLKLDASLPQSEIFSRIKQRV 199


>UniRef50_A0JSU5 Thymidylate kinase n=2 Tax=Micrococcaceae RepID=A0JSU5_ARTS2
          Length = 226

 Score = 42.8 bits (99), Expect = 0.009,   Method: Composition-based stats.
 Identities = 42/214 (19%), Positives = 70/214 (32%), Gaps = 32/214 (14%)

Query: 8   IINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIG 67
           +    P   IA  G DG+GKST  A+L   L +R     +   +  G            G
Sbjct: 1   MTTQNPGLFIAFEGGDGAGKSTQAAALAGALDSRG--IRVLRTREPG------------G 46

Query: 68  APFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYP 127
            P G  L  ++  +            AL+    +   A+  + +L   ++G +++TDRY 
Sbjct: 47  TPIGEKL--RSLVLDHGHGHIDARTEALI--FAASRAAHADQVILPALERGEIVLTDRYI 102

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMAS-YLPVLLIRLGIDEQTAFAR 186
              V    + G      T     +           +W  S   P L + L +D      R
Sbjct: 103 DSSVA---YQGAGRDLGTAAVRDLN----------EWATSGLQPDLTVLLDVDPAVGRLR 149

Query: 187 KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHP 220
           +     A  + +              L+L    P
Sbjct: 150 RTAGDAAEDRMESEADEFHAKIRTAFLDLAADRP 183


>UniRef50_C4RPM7 Thymidylate kinase n=1 Tax=Micromonospora sp. ATCC 39149
           RepID=C4RPM7_9ACTO
          Length = 239

 Score = 42.8 bits (99), Expect = 0.010,   Method: Composition-based stats.
 Identities = 42/227 (18%), Positives = 75/227 (33%), Gaps = 35/227 (15%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
           +R +A++G DGSGK+T    L   L A       +      R    I+Q   +G P    
Sbjct: 1   MRAVALIGIDGSGKTTQAHYLAEALTAAGRPATYHRNAGGRRWLGRIAQ--RLGRPDAER 58

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           L  ++  +  +         A+ + L+S                G   + DRY   +   
Sbjct: 59  LVGRSGLLAVESVLR---WLAIAVALVS------------CLVTGRTAVMDRYSACQYAS 103

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF----ARKPD 189
            R  G        G  W + L +   +++       P +   L +D   A+     R  D
Sbjct: 104 IRAHG--------GQRWER-LARAGYRIFP-----PPQVTFLLAVDPAEAYRRIERRGTD 149

Query: 190 HQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
           H+            +        + +D   P +E+ +     + A L
Sbjct: 150 HETMGWLSAADTAYRTLPEFPSFVVVDAGSPPEEVSRQIRAHLAAWL 196


>UniRef50_Q6F0E1 Thymidylate kinase n=1 Tax=Mesoplasma florum RepID=KTHY_MESFL
          Length = 211

 Score = 42.8 bits (99), Expect = 0.010,   Method: Composition-based stats.
 Identities = 35/230 (15%), Positives = 74/230 (32%), Gaps = 45/230 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELA--ARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            I I G DGSGK+T    +   L                          LP+        
Sbjct: 2   FITIEGMDGSGKTTALQRVKQYLEDLNYKVVM-----------TREPGGLPLSEKIRELI 50

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           L         K        T  ++  ++  + +  + +    ++G+++I+DR+       
Sbjct: 51  L--------NKDGVGMEPWTEALL-FIAARKEHLEKVIKPYLKKGYIVISDRF------- 94

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---KPDH 190
              D     +       +  L + +  + +    +LP L +   +  + A  R   +P+ 
Sbjct: 95  --MDSTTAYQGGARGLGVDYLNELQKNILE---GFLPDLTLYFELSFEDAEKRLSARPEE 149

Query: 191 Q--LAALQEKIAVTPQLTFNG------AKILELDGRHPADEILQASLRAI 232
           +  L     K     +L F         +I  +D     +E+ + + + I
Sbjct: 150 KNRLDEEGRKFKEAVKLAFEELVVKEPNRITVIDASKSPEEVFEETKKVI 199


>UniRef50_Q115I0 Thymidylate kinase n=10 Tax=Bacteria RepID=KTHY_TRIEI
          Length = 225

 Score = 42.4 bits (98), Expect = 0.011,   Method: Composition-based stats.
 Identities = 33/222 (14%), Positives = 70/222 (31%), Gaps = 30/222 (13%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           + I   G +G GK+T    L + L     +  I        +   I++ P  G   G+ L
Sbjct: 4   KFIVFEGVEGGGKTTQIELLQDWLLETGESRQILPKSIDLDLEVVITREPG-GTKLGKAL 62

Query: 75  RS--KAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLC-KSQQGFLLITDRYPQVEV 131
           R    +  V  +            + L +  RA     ++    ++G +++ DR+    +
Sbjct: 63  RELLLSPDVLAEKIQETSE-----LLLYAADRAQHIEALIKPCLERGTIVLCDRFIDSTI 117

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----- 186
               + G            +  +                 L   L ID +   AR     
Sbjct: 118 A---YQGYGRGLDVELIKQLNYIAT---------GGLKSDLTFWLDIDVEIGLARAKSRG 165

Query: 187 ---KPDHQLAALQEKIAV-TPQLTFNGAKILELDGRHPADEI 224
              + +        ++     +L  N + I+ +D     +++
Sbjct: 166 NFDRMEQANIEFHRRVQQGYQELAKNNSLIVRIDANLTREKV 207


>UniRef50_A0RXT4 Thymidylate kinase n=1 Tax=Cenarchaeum symbiosum RepID=A0RXT4_CENSY
          Length = 186

 Score = 42.4 bits (98), Expect = 0.012,   Method: Composition-based stats.
 Identities = 38/197 (19%), Positives = 61/197 (30%), Gaps = 38/197 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I I GCD +GK T    L   L  +     ++               P    P G+ ++
Sbjct: 7   IIVIEGCDQAGKQTQAGLLAGALNRKGRKARVF-------------AFPDYTTPVGKMMK 53

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                   K     G    +   L +  R  K  ++   S  G + I DRY Q  +    
Sbjct: 54  --------KQLEGRGFEPRVFHCLAAANRWEKAGEIRAASSGGSVAILDRYRQSNMVYGV 105

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD-HQLAA 194
            +G             + L   +  L          ++I L I ++ AF RKP     ++
Sbjct: 106 LNG----------LSRRWLAGLDAGL------PRADVVILLDIKQKEAFRRKPSGRDPSS 149

Query: 195 LQEKIAVTPQLTFNGAK 211
                    Q    G  
Sbjct: 150 GTHHSPSRWQQNTGGPP 166


>UniRef50_B0MX01 Putative uncharacterized protein n=1 Tax=Alistipes putredinis DSM
           17216 RepID=B0MX01_9BACT
          Length = 225

 Score = 42.4 bits (98), Expect = 0.012,   Method: Composition-based stats.
 Identities = 36/163 (22%), Positives = 56/163 (34%), Gaps = 21/163 (12%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I + G DG+GKST    LV  + A+   E  +L              PV G    R+L 
Sbjct: 2   LIVLEGLDGAGKSTQV-ELVRRMFAQEGVESHFLHFPRFDA-------PVYGELIARFL- 52

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                   +          LV  L +  RA    ++ C    G  ++ DRY    V GF+
Sbjct: 53  ------RGELGAVDKVDPYLVALLFAGDRADAAAQLRCWLDAGHAVVLDRYVYSNV-GFQ 105

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGI 178
               +L          + +   E   Y       P + + L +
Sbjct: 106 C--AKLPAGDRQEELRRWILDLEFGYY---GIPRPDVSLFLDV 143


>UniRef50_O05891 Thymidylate kinase n=38 Tax=Actinomycetales RepID=KTHY_MYCTU
          Length = 214

 Score = 42.4 bits (98), Expect = 0.013,   Method: Composition-based stats.
 Identities = 31/171 (18%), Positives = 60/171 (35%), Gaps = 23/171 (13%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IAI G DG+GK TL   L                +++GR        P  G      + 
Sbjct: 2   LIAIEGVDGAGKRTLVEKLSGAF------------RAAGR-SVATLAFPRYGQSVAADIA 48

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           ++A  +H +      ++ A+   L +  RA     +    +   ++I DRY         
Sbjct: 49  AEA--LHGEHGDLASSVYAMA-TLFALDRAGAVHTIQGLCRGYDVVILDRY---VASNAA 102

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR 186
           +   +L +          +++ E   +  +    P   + L +  + A  R
Sbjct: 103 YSAARLHEN-AAGKAAAWVQRIE---FARLGLPKPDWQVLLAVSAELAGER 149


>UniRef50_B2UBZ3 Thymidylate kinase n=13 Tax=Proteobacteria RepID=KTHY_RALPJ
          Length = 205

 Score = 42.4 bits (98), Expect = 0.014,   Method: Composition-based stats.
 Identities = 42/229 (18%), Positives = 73/229 (31%), Gaps = 41/229 (17%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           + I   G DG+GKST     +   A ++  +   LG+        +++ P  G P G  L
Sbjct: 4   KFITFEGIDGAGKST----HLAWFAQQLQAKLAPLGKK-----VVVTREPG-GTPLGERL 53

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           R    H      T      AL++   +  R +    +      G  +I+DR+       F
Sbjct: 54  REVLLHERMHLETE-----ALLM--FASRREHIAEVIQPALDAGDWVISDRFTDAT---F 103

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMAS-YLPVLLIRLGIDEQTAF-----ARKP 188
            + G                  R   L  W+     P   I   +  + A      AR P
Sbjct: 104 AYQGGGRGLA----------IDRLEALEHWVQQGLQPTKTILFDLAPEIAAARLADARTP 153

Query: 189 DHQLAA-----LQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAI 232
           D   A      L+ +     +      + + L+      +I +     +
Sbjct: 154 DKFEAESAQFFLRTRAEYLRRAAAEPDRFVVLNANRERSDIQKDLENLL 202


>UniRef50_D1S562 Thymidylate kinase n=1 Tax=Micromonospora aurantiaca ATCC 27029
           RepID=D1S562_9ACTO
          Length = 248

 Score = 42.0 bits (97), Expect = 0.015,   Method: Composition-based stats.
 Identities = 42/228 (18%), Positives = 73/228 (32%), Gaps = 43/228 (18%)

Query: 17  IAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLRS 76
           +A++G DGSGK+T    L   L A       +      R    I+Q   +G P  + L  
Sbjct: 17  VALIGIDGSGKTTQAHRLAQALTAAGRPATYHRNAGGRRWLGRIAQ--RVGRPDAQRLVG 74

Query: 77  KAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFRF 136
           +                 L++             +L     G   + DR+   +    R 
Sbjct: 75  RD---------------GLLVVESVLRWLAIALALLSCLVTGRTAVMDRWSACQYASIRA 119

Query: 137 DGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF----ARKPDHQ- 191
            G        G  W + L +   +++       P +   L +D   A+     R  DH+ 
Sbjct: 120 HG--------GQRWER-LARAGYRIFP-----APRVTFLLTVDPAEAYRRIERRGTDHET 165

Query: 192 ---LAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
              L A        P+        + +DG  P +E+ +     +   L
Sbjct: 166 MEWLTAAAAAYRDLPEYG----SFVVVDGTGPPEEVARRIRAHLSEWL 209


>UniRef50_UPI0001BC6A77 thymidylate kinase n=1 Tax=Buchnera aphidicola str. LSR1
           (Acyrthosiphon pisum) RepID=UPI0001BC6A77
          Length = 219

 Score = 41.6 bits (96), Expect = 0.020,   Method: Composition-based stats.
 Identities = 34/201 (16%), Positives = 69/201 (34%), Gaps = 31/201 (15%)

Query: 19  IVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLRSKA 78
           I G +G+GK+      +  L  +   +++ L +  G           I     R ++ K 
Sbjct: 16  IEGLEGAGKTNACI-CIKNLLKKNSIKNVLLVRQPGSTP--------IAEDIRRLIKKKF 66

Query: 79  AHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFRFDG 138
              +    T       L++Y  +       +K+    + G  +I+DR+   ++    + G
Sbjct: 67  NDDNLIKETE-----LLLMY--AARIQLVEKKIKPALKNGIWVISDRH---DLSSLAYQG 116

Query: 139 PQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAALQEK 198
             L       G  K +  +   L+  + +++P L I L +  +   AR        L   
Sbjct: 117 GGL-------GIPKKIIYQLQSLF--LNNFIPDLTIYLDVSPEIGLARALKRNPLDL--- 164

Query: 199 IAVTPQLTFNGAKILELDGRH 219
           I       F   +   L+   
Sbjct: 165 IESRSLFFFKKTRRCYLEKSK 185


>UniRef50_B7GT80 Thymidylate kinase n=2 Tax=Actinobacteridae RepID=KTHY_BIFLI
          Length = 233

 Score = 41.6 bits (96), Expect = 0.023,   Method: Composition-based stats.
 Identities = 41/231 (17%), Positives = 73/231 (31%), Gaps = 39/231 (16%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            ++  G DG GK+T    L   L A+  T  +        +G+ I QL + G   G    
Sbjct: 5   FVSFEGVDGVGKTTQVERLRAYLEAQGRTVVVTREPGGTVLGKAIRQLLLHGVDGGAVDI 64

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLC-KSQQGFLLITDRYPQVEVPGF 134
           +  A                   L +  RA    + +    ++G ++ITDRY    +  +
Sbjct: 65  APRAEA----------------LLFAADRAQHVAETIRPALERGEVVITDRYLDSSLA-Y 107

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMA-SYLPVLLIRLGIDEQTAFAR--KPDHQ 191
           +  G +L                   L  W   + LP     L +D   +  R    + +
Sbjct: 108 QAGGRELTPEEI------------RSLSMWATNNLLPDRTYLLDMDPALSHNRLEHAEDR 155

Query: 192 LAALQEKIAVTPQLTFNGAKILE------LDGRHPADEILQASLRAIHAAL 236
           + +         +  F      E      +D     +++  A    I   L
Sbjct: 156 MESAGSDFQSRTRQAFLDLAAAEPNRFHVIDASQSIEQVWSAIEADIQTLL 206


>UniRef50_Q1H169 Thymidylate kinase n=2 Tax=Methylophilales RepID=KTHY_METFK
          Length = 203

 Score = 41.2 bits (95), Expect = 0.026,   Method: Composition-based stats.
 Identities = 36/226 (15%), Positives = 72/226 (31%), Gaps = 45/226 (19%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           R I + G DG+GKS+   S+V+ L  R                      P+ G      L
Sbjct: 4   RFITLEGMDGAGKSSHIESIVSVLEGRG---------LEVVSTREPGGTPL-GEKLRELL 53

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
             +  HV  +            + + +  R +    +     +G  +++DR+       +
Sbjct: 54  LHERMHVETE-----------TLLMFAARREHIAEVIEPALARGAWVVSDRFTDASFA-Y 101

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWM-ASYLPVLLIRLGIDEQT-----AFARKP 188
           +  G  +              ++   L  W+     P L +   +  +      A AR P
Sbjct: 102 QCGGRGVP------------CEKVEALEAWVHPDLQPDLTLLFDVPVEISVARLAAARTP 149

Query: 189 DH-QLAAL----QEKIAVTPQLTFNGAKILELDGRHPADEILQASL 229
           D  +  +     + +     +      +   +DG  P D + +  L
Sbjct: 150 DKFERESAEFFRRIRNGYLARAEAQPQRFRLIDGNRPMDTVRKEVL 195


>UniRef50_Q1QX49 Thymidylate kinase n=11 Tax=Proteobacteria RepID=KTHY_CHRSD
          Length = 212

 Score = 41.2 bits (95), Expect = 0.027,   Method: Composition-based stats.
 Identities = 29/175 (16%), Positives = 55/175 (31%), Gaps = 29/175 (16%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
           TP R I + G +G GKST  A + + L+AR                      P   A   
Sbjct: 2   TPGRFITLEGGEGVGKSTNVAFVCDWLSARGIEVVR---------TREPGGTPRAEAIRE 52

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEV 131
             L        ++ +         ++ + +    +   ++     +G  ++ DR+     
Sbjct: 53  LLLDPAPQEPLDETAE--------LLLMFAARAQHLAARIRPALARGAWVVCDRFTDAT- 103

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR 186
             F + G            ++ L Q+            P L + L +  + A  R
Sbjct: 104 --FAYQGGGRGLDETRIATLEALVQQ---------GLQPDLTLLLDMPVEAAQRR 147


>UniRef50_Q1IJX5 Thymidylate kinase-like n=1 Tax=Candidatus Koribacter versatilis
           Ellin345 RepID=Q1IJX5_ACIBL
          Length = 228

 Score = 41.2 bits (95), Expect = 0.029,   Method: Composition-based stats.
 Identities = 31/226 (13%), Positives = 68/226 (30%), Gaps = 24/226 (10%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPT---EHIYLGQSSGRIGEWISQLPVIGAPFGR 72
           ++   G D  GKST    L+ +L +R        + LG + G  G       ++    G+
Sbjct: 3   LLTFSGIDCCGKSTQIELLMEQLKSRGNAVSYMWLRLGYTPGFQGLK----SLLRRVAGK 58

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQG-FLLITDRYPQVEV 131
                      +     G    L +YL      ++   +    +    ++I DRY +   
Sbjct: 59  KAAPAGNSPQRERFMKQGWKRRLWLYLAIGDMFWQTAVVTRWKRSADIIVICDRYLRDSE 118

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----- 186
                + P+         W        L          P + + + +  + +  R     
Sbjct: 119 FDLAMNFPE----DTVTRWWSWRLMSALAA-------RPDVALLMDLSFEESLRRSLAKS 167

Query: 187 KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAI 232
           +P       + + A   + +    +   +D      +I    +  +
Sbjct: 168 EPFPDSEDRRRERAEMYRNSVRDGQWHVIDATRDIADIHGEIMGLV 213


>UniRef50_B0D7L7 Predicted protein n=2 Tax=Agaricales RepID=B0D7L7_LACBS
          Length = 228

 Score = 40.9 bits (94), Expect = 0.034,   Method: Composition-based stats.
 Identities = 41/198 (20%), Positives = 65/198 (32%), Gaps = 41/198 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I I G D SGK+T T+ L   L A      +          ++  +  VIG     YLR
Sbjct: 5   FIVIEGLDRSGKTTQTSLLHTRLEAEGIQAKLM---------KFPDRTTVIGQMIDSYLR 55

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           S +                ++  L S  R      +    + G  +I DRY    +    
Sbjct: 56  SDSE-----------LDDHVIHLLFSANRWELASYITQLLEAGTPIICDRYAFSGIAFSA 104

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMAS-----YLPVLLIRLGIDEQTAFAR---- 186
             G  +  +T                Y+W  S       P L++ L I  + A  R    
Sbjct: 105 SKG--IPSSTPSPKLP----------YEWCRSPDIGLPAPDLVLFLDIAPERAKLRGGYG 152

Query: 187 KPDHQLAALQEKIAVTPQ 204
           +  ++   LQ ++    Q
Sbjct: 153 EERYEKEELQARVRGIFQ 170


>UniRef50_D0LII3 Thymidylate kinase n=1 Tax=Haliangium ochraceum DSM 14365
           RepID=D0LII3_HALO1
          Length = 210

 Score = 40.9 bits (94), Expect = 0.037,   Method: Composition-based stats.
 Identities = 44/233 (18%), Positives = 84/233 (36%), Gaps = 47/233 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I + G DGSG ST T  L +  AAR  + H     S+G +G  + ++            
Sbjct: 8   LIVLEGIDGSGTSTQTRLLCDAFAARGRSTHATHEPSTGPVGLLLREML----------- 56

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                     +  P + T L +   +    +  R++      G L+++DR+    +    
Sbjct: 57  --------AGAHAPVDQTTLSLLYAADRADHVQREVEPALAAGKLVVSDRWYHSSLA--- 105

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH-QLAA 194
           + G       G   W+  L +             P L I L +  + A  R+ D  +   
Sbjct: 106 YQGAG-----GTRDWVAALNRYARA---------PDLTIFLEVAAEIAARRRADDGRSEE 151

Query: 195 LQEKIAVTPQLTF----------NGAKILELDGRHPADEILQASLRAIHAALS 237
           + +++ +  ++               +I  LDG  P   +    +R +  AL+
Sbjct: 152 IFDRLEIQQRVAADYREVIDSLRGRERIEVLDGERPLAAVSADIVRLVEDALA 204


>UniRef50_C9RA68 Thymidylate kinase n=1 Tax=Ammonifex degensii KC4
           RepID=C9RA68_AMMDK
          Length = 202

 Score = 40.9 bits (94), Expect = 0.038,   Method: Composition-based stats.
 Identities = 37/227 (16%), Positives = 73/227 (32%), Gaps = 39/227 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G DG GK+T    L  +L  +             R+GE I +L            
Sbjct: 5   FIVLEGIDGVGKTTQARILAQKLREQGREVVEVREPGGTRLGEAIRELL----------- 53

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                  +K    P     L    L+         +     +G +++ DR+    +    
Sbjct: 54  -------QKEELAPWAEACL---FLASRAQLVEEVIKPALAKGKVVVGDRF---SLSTLA 100

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
           + G    +          +               P L + + +  + A AR        +
Sbjct: 101 YQGALGLEPDKLAQLNSWVTG----------GLEPDLTLVIDLKAEEALARGKGDLREEI 150

Query: 196 QEKIAVTPQLTFN-----GAKILELDGRHPADEILQASLRAIHAALS 237
           ++K+ +  +   N      AK+L +DG+   +E+ +     +  AL+
Sbjct: 151 RQKLEIVRERYLNLAKERAAKVLVVDGQGSVEEVSRRIWALVEEALA 197


>UniRef50_D1WS25 Thymidylate kinase n=10 Tax=Actinomycetales RepID=D1WS25_9ACTO
          Length = 1084

 Score = 40.9 bits (94), Expect = 0.040,   Method: Composition-based stats.
 Identities = 36/192 (18%), Positives = 71/192 (36%), Gaps = 36/192 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            +A+ G DG+GKST   +L + + ++     +     +  IG+ +  + +  +  G   R
Sbjct: 509 FLALEGGDGAGKSTQVEALADWIRSKGHEVVVTREPGATPIGKRLRSILLDVSSAGLSNR 568

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           ++A       +    ++                  +    ++G ++I+DRY    V  ++
Sbjct: 569 AEALLYAADRAEHVDSV------------------VRPALERGAIVISDRYIDSSVA-YQ 609

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---KPDH-- 190
             G  LA T       +                +P L + L +D  TA  R    PD   
Sbjct: 610 GAGRDLAPTEIA-RISRWATS----------GLVPHLTVLLDVDPATARERFTEAPDRLE 658

Query: 191 -QLAALQEKIAV 201
            + AA  E++  
Sbjct: 659 SEPAAFHERVRS 670


>UniRef50_Q13YY3 Thymidylate kinase n=7 Tax=Burkholderiales RepID=KTHY_BURXL
          Length = 206

 Score = 40.1 bits (92), Expect = 0.062,   Method: Composition-based stats.
 Identities = 37/221 (16%), Positives = 75/221 (33%), Gaps = 36/221 (16%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           + I   G DG+GK+T  +     L  ++         S+GR    +++ P  G P G  +
Sbjct: 5   KFITFEGIDGAGKTTHLSWFRERLEQKVA--------STGR-SVVMTREPG-GTPLGEQI 54

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           R    H      T      AL++   +  R +    +     +G  +++DR+       F
Sbjct: 55  REIVLHQKMDLETE-----ALLM--FALRRQHLAEVIEPALARGDWVLSDRFTDAT---F 104

Query: 135 RFDGPQLA-KTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLA 193
            + G              + ++            + P L +   +D + A  R+     A
Sbjct: 105 AYQGGGRGLPRDKLETLERWVQG----------GFQPDLTVLFDLDPEVASERR---SAA 151

Query: 194 ALQEKIAVTPQLTFNGAKILELDGRH--PADEILQASLRAI 232
              ++     +  F+  +   L      P    +  S ++I
Sbjct: 152 RDPDRFESESEAFFSRTRAEYLRRAEEAPYRFAIIDSAQSI 192


>UniRef50_A2SN76 Thymidylate kinase n=3 Tax=Betaproteobacteria RepID=A2SN76_METPP
          Length = 224

 Score = 40.1 bits (92), Expect = 0.069,   Method: Composition-based stats.
 Identities = 29/168 (17%), Positives = 51/168 (30%), Gaps = 35/168 (20%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           R+I +   DG+GKST   ++V  L      E +        +       PV        L
Sbjct: 9   RMITLSALDGAGKSTQVQTVVERLRDYYGIEVV--------VTREPGGSPVAERLRELVL 60

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
                              A ++   +  + +  + +    Q G  ++ DR+        
Sbjct: 61  HGDVID-----------PVAEMMIFFAARQDHLAQVIRPALQAGRWVVCDRFVDCS---- 105

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMA--SYLPVLLIRLGIDE 180
                  A    G G    L + E +  + M    + P L   L I+ 
Sbjct: 106 ------WAYQVRGRG----LARAEFEALEKMVLRGWRPDLTFLLDIEP 143


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q46843 Uncharacterized ATP-binding protein yghS n=43 Ta...   246   6e-64
UniRef50_C8WFA2 Putative uncharacterized protein n=3 Tax=Zymomon...   227   2e-58
UniRef50_Q46844 Uncharacterized ATP-binding protein yghT n=39 Ta...   225   7e-58
UniRef50_P64573 Uncharacterized ATP-binding protein yghR n=42 Ta...   204   2e-51
UniRef50_Q5NMW8 Conserved predicted protein with nucleoside trip...   195   8e-49
UniRef50_Q2LPR0 Hypothetical cytosolic protein n=1 Tax=Syntrophu...   176   6e-43
UniRef50_C5KB73 Thymidylate kinase, putative n=2 Tax=Perkinsus m...   158   1e-37
UniRef50_A6S4P1 Putative uncharacterized protein n=2 Tax=Sclerot...   158   2e-37
UniRef50_C6TJ88 Putative uncharacterized protein n=1 Tax=Glycine...   156   6e-37
UniRef50_Q0WW55 Thymidylate kinase-like protein n=22 Tax=Eukaryo...   153   6e-36
UniRef50_A8Q2K3 Putative uncharacterized protein n=1 Tax=Malasse...   151   2e-35
UniRef50_B0EQM5 Thymidylate kinase, putative n=2 Tax=Entamoeba R...   150   4e-35
UniRef50_P36590 Thymidylate kinase n=2 Tax=Ascomycota RepID=KTHY...   148   1e-34
UniRef50_Q3B752 Zgc:123174 n=5 Tax=root RepID=Q3B752_DANRE            148   1e-34
UniRef50_B6YSZ4 Probable thymidylate kinase n=5 Tax=Thermococcac...   148   1e-34
UniRef50_B6QFH6 Thymidylate kinase n=13 Tax=Eurotiomycetidae Rep...   147   4e-34
UniRef50_Q4P9K7 Putative uncharacterized protein n=2 Tax=Fungi/M...   145   1e-33
UniRef50_C6A0S1 Probable thymidylate kinase n=4 Tax=Thermococcus...   145   2e-33
UniRef50_Q67JB0 Thymidylate kinase n=1 Tax=Symbiobacterium therm...   144   3e-33
UniRef50_A5N3T4 Tmk n=32 Tax=Bacteria RepID=A5N3T4_CLOK5              144   3e-33
UniRef50_C0EEB4 Putative uncharacterized protein n=1 Tax=Clostri...   143   6e-33
UniRef50_C3ZEC2 Putative uncharacterized protein n=1 Tax=Branchi...   143   7e-33
UniRef50_B5IF40 Thymidylate kinase n=2 Tax=Aciduliprofundum boon...   141   1e-32
UniRef50_D2A7H7 Putative ATP-binding protein yghT n=3 Tax=Entero...   141   2e-32
UniRef50_A2QUJ3 Catalytic activity: ATP + thymidine 5'-phosphate...   141   3e-32
UniRef50_Q17LP5 Thymidylate kinase, putative n=4 Tax=Culicidae R...   140   3e-32
UniRef50_C1BRK2 Thymidylate kinase n=1 Tax=Caligus rogercresseyi...   140   3e-32
UniRef50_B8D357 Thymidylate kinase n=1 Tax=Desulfurococcus kamch...   139   8e-32
UniRef50_Q22018 Probable thymidylate kinase n=3 Tax=Caenorhabdit...   137   2e-31
UniRef50_D1S998 Thymidylate kinase n=1 Tax=Micromonospora aurant...   137   3e-31
UniRef50_A4RZW8 Predicted protein n=13 Tax=Eukaryota RepID=A4RZW...   137   3e-31
UniRef50_A6NRP2 Putative uncharacterized protein n=2 Tax=Bacteri...   136   4e-31
UniRef50_A1VCE6 Thymidylate kinase n=15 Tax=Bacteria RepID=KTHY_...   136   5e-31
UniRef50_UPI0001C375B1 putative thymidylate kinase n=1 Tax=Rumin...   135   1e-30
UniRef50_Q45RR2 Deoxythymidylate kinase n=1 Tax=Cyprinid herpesv...   134   3e-30
UniRef50_D2RGJ1 Thymidylate kinase n=2 Tax=Archaeoglobaceae RepI...   133   4e-30
UniRef50_A3DM71 Probable thymidylate kinase n=1 Tax=Staphylother...   133   5e-30
UniRef50_Q8SS22 THYMIDYLATE KINASE n=1 Tax=Encephalitozoon cunic...   133   6e-30
UniRef50_D1YVU8 Probable thymidylate kinase n=2 Tax=Euryarchaeot...   131   1e-29
UniRef50_A9A2S6 Thymidylate kinase n=1 Tax=Nitrosopumilus mariti...   131   1e-29
UniRef50_Q46DH6 Probable thymidylate kinase n=4 Tax=Methanosarci...   131   2e-29
UniRef50_C7PHF5 Thymidylate kinase n=1 Tax=Chitinophaga pinensis...   131   2e-29
UniRef50_O30175 Probable thymidylate kinase n=1 Tax=Archaeoglobu...   130   3e-29
UniRef50_Q5ZVP1 Thymidylate kinase n=5 Tax=Legionella RepID=KTHY...   130   4e-29
UniRef50_Q601T1 Thymidylate kinase n=6 Tax=Mycoplasma RepID=KTHY...   130   5e-29
UniRef50_D1BLN7 Thymidylate kinase n=15 Tax=Bacteria RepID=D1BLN...   129   7e-29
UniRef50_Q0A8S2 Thymidylate kinase n=16 Tax=Gammaproteobacteria ...   129   8e-29
UniRef50_A1RTS9 Thymidylate kinase n=3 Tax=Thermoproteaceae RepI...   129   8e-29
UniRef50_A9BCY7 Thymidylate kinase n=9 Tax=Prochlorococcus marin...   129   8e-29
UniRef50_C4KZW9 Thymidylate kinase n=1 Tax=Exiguobacterium sp. A...   129   9e-29
UniRef50_B3T390 Putative Thymidylate kinase n=1 Tax=uncultured m...   128   1e-28
UniRef50_D2MMU9 dTMP kinase n=1 Tax=Bulleidia extructa W1219 Rep...   125   9e-28
UniRef50_B5YD95 Thymidylate kinase n=1 Tax=Dictyoglomus thermoph...   124   2e-27
UniRef50_A9DXA8 Thymidylate kinase n=1 Tax=Kordia algicida OT-1 ...   124   3e-27
UniRef50_Q254L6 Thymidylate kinase n=13 Tax=Chlamydiaceae RepID=...   123   5e-27
UniRef50_A7VTJ2 Putative uncharacterized protein n=2 Tax=Clostri...   122   9e-27
UniRef50_D2E8C8 ORF77 n=1 Tax=Anguillid herpesvirus 1 RepID=D2E8...   122   9e-27
UniRef50_A9ETA2 Putative Thymidylate kinase n=1 Tax=Sorangium ce...   121   2e-26
UniRef50_A3CPJ9 Thymidylate kinase n=29 Tax=Firmicutes RepID=KTH...   121   2e-26
UniRef50_Q0C176 Thymidylate kinase n=1 Tax=Hyphomonas neptunium ...   119   6e-26
UniRef50_A6LPM3 Thymidylate kinase n=175 Tax=Firmicutes RepID=KT...   119   8e-26
UniRef50_Q28SW8 Thymidylate kinase n=39 Tax=Rhodobacterales RepI...   119   8e-26
UniRef50_A6C348 Thymidylate kinase n=1 Tax=Planctomyces maris DS...   119   1e-25
UniRef50_A5G4M6 Thymidylate synthase / thymidylate kinase n=3 Ta...   117   3e-25
UniRef50_Q581B1 Thymidylate kinase, putative n=3 Tax=Trypanosoma...   116   5e-25
UniRef50_D1PL57 dTMP kinase n=1 Tax=Subdoligranulum variabile DS...   116   6e-25
UniRef50_Q1J3J7 Thymidylate kinase-like protein n=1 Tax=Deinococ...   116   8e-25
UniRef50_C6HZ31 Thymidylate kinase n=1 Tax=Leptospirillum ferrod...   116   8e-25
UniRef50_Q1NU71 Putative uncharacterized protein n=1 Tax=delta p...   115   1e-24
UniRef50_Q9HLZ2 Probable thymidylate kinase n=2 Tax=Thermoplasma...   115   1e-24
UniRef50_Q6L016 Probable thymidylate kinase n=1 Tax=Picrophilus ...   114   3e-24
UniRef50_C7DHA0 dTMP kinase n=1 Tax=Candidatus Micrarchaeum acid...   111   2e-23
UniRef50_B1V9T6 Thymidylate kinase n=9 Tax=16SrXII (Stolbur grou...   109   1e-22
UniRef50_C4DQR2 Thymidylate kinase n=1 Tax=Stackebrandtia nassau...   108   1e-22

Sequences not found previously or not previously below threshold:

UniRef50_B0D7L7 Predicted protein n=2 Tax=Agaricales RepID=B0D7L...   146   4e-34
UniRef50_B7Q0D8 Thymidylate kinase, putative n=1 Tax=Ixodes scap...   145   2e-33
UniRef50_B3LDF8 Thymidylate kinase, putative n=5 Tax=Plasmodium ...   142   1e-32
UniRef50_Q5KK13 Thymidylate kinase, putative n=2 Tax=Filobasidie...   141   2e-32
UniRef50_B5Y400 Predicted protein n=1 Tax=Phaeodactylum tricornu...   141   2e-32
UniRef50_Q22U70 Thymidylate kinase family protein n=1 Tax=Tetrah...   138   2e-31
UniRef50_B6K7E8 Thymidylate kinase n=1 Tax=Schizosaccharomyces j...   137   3e-31
UniRef50_B8BUD4 Predicted protein n=1 Tax=Thalassiosira pseudona...   135   1e-30
UniRef50_Q8SZQ0 RE69454p (Fragment) n=18 Tax=Drosophila RepID=Q8...   135   1e-30
UniRef50_C9SNG5 Thymidylate kinase n=7 Tax=Sordariomycetes RepID...   133   7e-30
UniRef50_D0MVS5 Thymidylate kinase n=1 Tax=Phytophthora infestan...   132   8e-30
UniRef50_P23919 Thymidylate kinase n=22 Tax=Euteleostomi RepID=K...   132   9e-30
UniRef50_A0CKK9 Chromosome undetermined scaffold_2, whole genome...   130   4e-29
UniRef50_B9KXL4 Thymidylate kinase n=11 Tax=Bacteria RepID=KTHY_...   130   4e-29
UniRef50_A5DSK9 Thymidylate kinase n=8 Tax=Saccharomycetales Rep...   129   6e-29
UniRef50_D0YPY2 Thymidylate kinase n=3 Tax=Mobiluncus RepID=D0YP...   129   8e-29
UniRef50_Q8DHA4 Thymidylate kinase n=2 Tax=Cyanobacteria RepID=K...   128   1e-28
UniRef50_UPI0001AECAE5 thymidylate kinase n=6 Tax=Streptomyces R...   128   1e-28
UniRef50_Q4UE21 Thymidylate kinase, putative n=2 Tax=Theileria R...   128   2e-28
UniRef50_B8HXT9 Thymidylate kinase n=8 Tax=Cyanobacteria RepID=K...   128   2e-28
UniRef50_B6AIV4 Thymidylate kinase family protein n=1 Tax=Crypto...   127   3e-28
UniRef50_D2Q7V9 Thymidylate kinase n=2 Tax=Bifidobacterium denti...   126   4e-28
UniRef50_Q115I0 Thymidylate kinase n=10 Tax=Bacteria RepID=KTHY_...   126   5e-28
UniRef50_Q54GN2 Thymidylate kinase n=1 Tax=Dictyostelium discoid...   126   5e-28
UniRef50_Q6AJE2 Thymidylate kinase n=1 Tax=Desulfotalea psychrop...   126   6e-28
UniRef50_Q2JR37 Thymidylate kinase n=4 Tax=Bacteria RepID=KTHY_S...   126   6e-28
UniRef50_Q1D6W4 Thymidylate kinase n=7 Tax=Cystobacterineae RepI...   126   6e-28
UniRef50_B5YJ17 Thymidylate kinase n=1 Tax=Thermodesulfovibrio y...   126   7e-28
UniRef50_O81650 Thymidylate kinase (Fragment) n=1 Tax=Arabidopsi...   126   8e-28
UniRef50_C4R413 Thymidylate and uridylate kinase n=1 Tax=Pichia ...   125   1e-27
UniRef50_A5DF16 Putative uncharacterized protein n=3 Tax=Sacchar...   125   1e-27
UniRef50_B7GT80 Thymidylate kinase n=2 Tax=Actinobacteridae RepI...   125   2e-27
UniRef50_B0K7K7 Thymidylate kinase n=20 Tax=Firmicutes RepID=KTH...   124   2e-27
UniRef50_B3SBN8 Putative uncharacterized protein n=2 Tax=Metazoa...   124   2e-27
UniRef50_UPI000186EA7B thymidylate kinase, putative n=1 Tax=Pedi...   124   2e-27
UniRef50_UPI0001BC2C76 thymidylate kinase n=1 Tax=Brevibacterium...   124   2e-27
UniRef50_C8W2Q7 Thymidylate kinase n=1 Tax=Desulfotomaculum acet...   123   4e-27
UniRef50_A5FR84 Thymidylate kinase n=5 Tax=Dehalococcoides RepID...   123   4e-27
UniRef50_Q3A3X3 Thymidylate kinase n=3 Tax=Deltaproteobacteria R...   123   5e-27
UniRef50_P00572 Thymidylate kinase n=11 Tax=Saccharomycetaceae R...   123   7e-27
UniRef50_Q9C2R7 Related to thymidylate kinase n=1 Tax=Neurospora...   122   8e-27
UniRef50_Q3AG12 Thymidylate kinase n=2 Tax=Bacteria RepID=KTHY_C...   122   9e-27
UniRef50_Q8RDE6 Thymidylate kinase n=2 Tax=Thermoanaerobacterace...   122   9e-27
UniRef50_D2EGN9 dTMP kinase n=1 Tax=Candidatus Parvarchaeum acid...   121   2e-26
UniRef50_C8QYR9 Thymidylate kinase n=1 Tax=Desulfurivibrio alkal...   121   2e-26
UniRef50_B1ZU40 dTMP kinase n=3 Tax=Verrucomicrobia RepID=B1ZU40...   121   2e-26
UniRef50_B3DUA1 Thymidylate kinase n=8 Tax=Actinobacteridae RepI...   121   2e-26
UniRef50_Q0F3S1 Thymidylate kinase n=1 Tax=Mariprofundus ferroox...   121   2e-26
UniRef50_C5U715 dTMP kinase n=1 Tax=Methanocaldococcus infernus ...   121   2e-26
UniRef50_Q1QX49 Thymidylate kinase n=11 Tax=Proteobacteria RepID...   120   3e-26
UniRef50_B0MFL0 Putative uncharacterized protein n=5 Tax=Clostri...   120   4e-26
UniRef50_A7BBF9 Putative uncharacterized protein n=3 Tax=Actinob...   120   4e-26
UniRef50_A0ZZR0 Thymidylate kinase n=5 Tax=Actinobacteridae RepI...   120   4e-26
UniRef50_A5D690 Thymidylate kinase n=4 Tax=Clostridiales RepID=K...   120   4e-26
UniRef50_A8IRW9 Predicted protein (Fragment) n=1 Tax=Chlamydomon...   119   5e-26
UniRef50_Q6CW62 KLLA0B06556p n=1 Tax=Kluyveromyces lactis RepID=...   118   1e-25
UniRef50_A5WBP5 Thymidylate kinase n=4 Tax=Moraxellaceae RepID=K...   118   1e-25
UniRef50_Q91FS1 Putative thymidylate kinase 251L n=1 Tax=Inverte...   118   1e-25
UniRef50_D1A586 Thymidylate kinase n=1 Tax=Thermomonospora curva...   118   1e-25
UniRef50_B9XNP9 dTMP kinase n=1 Tax=bacterium Ellin514 RepID=B9X...   118   2e-25
UniRef50_C5RNT5 dTMP kinase n=2 Tax=Clostridia RepID=C5RNT5_CLOCL     118   2e-25
UniRef50_A8PE11 Thymidylate kinase, putative n=1 Tax=Brugia mala...   118   2e-25
UniRef50_A9MB09 Thymidylate kinase n=42 Tax=Alphaproteobacteria ...   118   2e-25
UniRef50_O67099 Thymidylate kinase n=2 Tax=Aquificaceae RepID=KT...   118   2e-25
UniRef50_A4XHH4 Thymidylate kinase n=1 Tax=Caldicellulosiruptor ...   118   2e-25
UniRef50_Q1PY20 Similar to thymidylate kinase n=1 Tax=Candidatus...   117   2e-25
UniRef50_Q9RY40 Thymidylate kinase n=14 Tax=Bacteria RepID=KTHY_...   117   3e-25
UniRef50_A9BG59 Thymidylate kinase n=11 Tax=Bacteria RepID=A9BG5...   117   4e-25
UniRef50_D1WS25 Thymidylate kinase n=10 Tax=Actinomycetales RepI...   117   4e-25
UniRef50_A2CD19 Thymidylate kinase n=16 Tax=Cyanobacteria RepID=...   116   4e-25
UniRef50_C0QI33 Thymidylate kinase n=1 Tax=Desulfobacterium auto...   116   6e-25
UniRef50_B6KVJ7 Thymidylate kinase, putative n=3 Tax=Toxoplasma ...   116   6e-25
UniRef50_C1ZEK7 Thymidylate kinase n=1 Tax=Planctomyces limnophi...   116   6e-25
UniRef50_UPI0001C3174B thymidylate kinase n=1 Tax=Conexibacter w...   116   6e-25
UniRef50_C1TMC0 Thymidylate kinase n=2 Tax=Synergistaceae RepID=...   116   6e-25
UniRef50_Q1H169 Thymidylate kinase n=2 Tax=Methylophilales RepID...   115   9e-25
UniRef50_Q2NIY4 Thymidylate kinase n=4 Tax=Candidatus Phytoplasm...   115   9e-25
UniRef50_B7IHT2 Thymidylate kinase n=10 Tax=Thermotogaceae RepID...   115   1e-24
UniRef50_D1N6G6 Thymidylate kinase n=1 Tax=Victivallis vadensis ...   115   1e-24
UniRef50_A7ANS1 Thymidylate kinase, putative n=1 Tax=Babesia bov...   115   1e-24
UniRef50_B4S1N2 Thymidylate kinase n=4 Tax=Alteromonadales RepID...   115   1e-24
UniRef50_B8DZY5 dTMP kinase n=1 Tax=Dictyoglomus turgidum DSM 67...   115   1e-24
UniRef50_D1CF94 Thymidylate kinase n=1 Tax=Thermobaculum terrenu...   115   1e-24
UniRef50_Q1NMK0 Thymidylate kinase n=1 Tax=delta proteobacterium...   114   2e-24
UniRef50_B6BTX5 Thymidylate kinase n=1 Tax=beta proteobacterium ...   114   2e-24
UniRef50_B7XIF1 Thymidylate kinase n=1 Tax=Enterocytozoon bieneu...   114   2e-24
UniRef50_C1YIK9 Thymidylate kinase n=1 Tax=Nocardiopsis dassonvi...   114   2e-24
UniRef50_Q2RZ38 Thymidylate kinase n=2 Tax=Rhodothermaceae RepID...   114   3e-24
UniRef50_Q0BT79 Thymidylate kinase n=6 Tax=Alphaproteobacteria R...   114   3e-24
UniRef50_Q13YY3 Thymidylate kinase n=7 Tax=Burkholderiales RepID...   114   3e-24
UniRef50_A6UTV9 Probable thymidylate kinase n=2 Tax=Methanococca...   114   3e-24
UniRef50_C5NX74 Thymidylate kinase n=1 Tax=Gemella haemolysans A...   114   3e-24
UniRef50_A1ZN65 Thymidylate kinase n=1 Tax=Microscilla marina AT...   113   4e-24
UniRef50_C7RBH0 Thymidylate kinase n=5 Tax=Gammaproteobacteria R...   113   4e-24
UniRef50_A3EQU8 Thymidylate kinase n=2 Tax=Leptospirillum sp. Gr...   113   5e-24
UniRef50_C9RA68 Thymidylate kinase n=1 Tax=Ammonifex degensii KC...   113   5e-24
UniRef50_Q2NHE3 Probable thymidylate kinase n=1 Tax=Methanosphae...   113   6e-24
UniRef50_A6VXL0 Thymidylate kinase n=2 Tax=Marinomonas RepID=KTH...   113   6e-24
UniRef50_Q5F9Z5 Thymidylate kinase n=59 Tax=Betaproteobacteria R...   113   7e-24
UniRef50_Q2J4Z0 Thymidylate kinase n=3 Tax=Frankia RepID=Q2J4Z0_...   113   7e-24
UniRef50_Q0AIL5 Thymidylate kinase n=22 Tax=Betaproteobacteria R...   113   8e-24
UniRef50_B1I165 Thymidylate kinase n=3 Tax=Firmicutes RepID=KTHY...   112   9e-24
UniRef50_Q2RMF8 Thymidylate kinase n=2 Tax=root RepID=Q2RMF8_MOOTA    112   1e-23
UniRef50_C7RD91 Thymidylate kinase n=6 Tax=Clostridiales Family ...   112   1e-23
UniRef50_C4V663 Thymidylate kinase n=1 Tax=Selenomonas flueggei ...   112   1e-23
UniRef50_B4S8U3 Thymidylate kinase n=11 Tax=Chlorobiaceae RepID=...   112   1e-23
UniRef50_Q6AB62 Thymidylate kinase n=4 Tax=Actinomycetales RepID...   112   1e-23
UniRef50_Q2K893 Thymidylate kinase protein n=9 Tax=Rhizobium Rep...   111   2e-23
UniRef50_Q55593 Thymidylate kinase n=7 Tax=Chroococcales RepID=K...   111   2e-23
UniRef50_B2GAE1 Thymidylate kinase n=32 Tax=Lactobacillales RepI...   111   2e-23
UniRef50_Q5FUU6 Thymidylate kinase n=9 Tax=Acetobacteraceae RepI...   111   2e-23
UniRef50_B2UBZ3 Thymidylate kinase n=13 Tax=Proteobacteria RepID...   111   3e-23
UniRef50_A0JSU5 Thymidylate kinase n=2 Tax=Micrococcaceae RepID=...   111   3e-23
UniRef50_C8PCQ1 dTMP kinase n=1 Tax=Lactobacillus iners DSM 1333...   110   3e-23
UniRef50_B0S2F7 Thymidylate kinase n=3 Tax=Clostridiales Family ...   110   4e-23
UniRef50_C0W270 Thymidylate kinase n=1 Tax=Actinomyces coleocani...   110   4e-23
UniRef50_B9JFC7 Thymidylate kinase n=4 Tax=cellular organisms Re...   110   4e-23
UniRef50_B5Y7S6 Thymidylate kinase n=1 Tax=Coprothermobacter pro...   110   4e-23
UniRef50_B2A320 dTMP kinase n=1 Tax=Natranaerobius thermophilus ...   109   5e-23
UniRef50_P59500 Thymidylate kinase n=5 Tax=Buchnera aphidicola R...   109   6e-23
UniRef50_D1SN75 Thymidylate kinase n=1 Tax=Methanocaldococcus sp...   109   6e-23
UniRef50_B8DAU8 Thymidylate kinase n=17 Tax=Listeria RepID=KTHY_...   109   7e-23
UniRef50_D0LII3 Thymidylate kinase n=1 Tax=Haliangium ochraceum ...   109   8e-23
UniRef50_A1WGM5 Thymidylate kinase n=15 Tax=Burkholderiales RepI...   109   9e-23
UniRef50_A4IJA6 Thymidylate kinase n=103 Tax=Bacteria RepID=KTHY...   109   9e-23
UniRef50_C5CHP2 Thymidylate kinase n=1 Tax=Kosmotoga olearia TBF...   109   9e-23
UniRef50_C3K0M9 Thymidylate kinase n=7 Tax=Gammaproteobacteria R...   109   9e-23
UniRef50_C3CT99 Thymidylate kinase n=1 Tax=Bacillus thuringiensi...   109   1e-22
UniRef50_A8MB58 Probable thymidylate kinase n=3 Tax=Thermoprotea...   109   1e-22
UniRef50_A9AV71 Thymidylate kinase n=6 Tax=Chloroflexi (class) R...   109   1e-22
UniRef50_B1YGD3 Thymidylate kinase n=2 Tax=Bacillales RepID=KTHY...   109   1e-22
UniRef50_Q1C6N6 Thymidylate kinase n=40 Tax=Enterobacteriaceae R...   108   1e-22
UniRef50_A6TJF7 dTMP kinase n=2 Tax=Alkaliphilus RepID=A6TJF7_ALKMQ   108   1e-22
UniRef50_C8W7S9 Thymidylate kinase n=3 Tax=Atopobium RepID=C8W7S...   108   1e-22
UniRef50_C6DKS8 Thymidylate kinase n=188 Tax=Gammaproteobacteria...   108   2e-22
UniRef50_A9NEH3 Thymidylate kinase n=1 Tax=Acholeplasma laidlawi...   108   2e-22
UniRef50_Q1ILM2 Thymidylate kinase n=1 Tax=Candidatus Koribacter...   108   2e-22
UniRef50_A0Z288 Thymidylate kinase n=1 Tax=marine gamma proteoba...   108   2e-22
UniRef50_UPI0000DB6E10 PREDICTED: similar to deoxythymidylate ki...   108   2e-22
UniRef50_Q6F0E1 Thymidylate kinase n=1 Tax=Mesoplasma florum Rep...   108   2e-22
UniRef50_A4ECY1 Putative uncharacterized protein n=3 Tax=Collins...   108   2e-22
UniRef50_A5CPG8 Thymidylate kinase n=28 Tax=Bacteria RepID=KTHY_...   108   2e-22
UniRef50_C9RR73 Thymidylate kinase n=1 Tax=Fibrobacter succinoge...   108   2e-22
UniRef50_C4K9M9 Thymidylate kinase n=8 Tax=Betaproteobacteria Re...   108   2e-22
UniRef50_A0Q893 Thymidylate kinase n=19 Tax=Francisella RepID=KT...   108   2e-22
UniRef50_B2UN87 Thymidylate kinase n=1 Tax=Akkermansia muciniphi...   108   2e-22
UniRef50_A9QS84 Thymidylate kinase n=3 Tax=Bacilli RepID=A9QS84_...   108   3e-22
UniRef50_C6XJM4 Thymidylate kinase n=1 Tax=Hirschia baltica ATCC...   107   3e-22
UniRef50_Q01Q29 Thymidylate kinase n=1 Tax=Candidatus Solibacter...   107   3e-22
UniRef50_D1Y158 dTMP kinase n=1 Tax=Pyramidobacter piscolens W54...   107   3e-22
UniRef50_B3QXL1 dTMP kinase n=1 Tax=Chloroherpeton thalassium AT...   107   3e-22
UniRef50_Q8UFA0 Thymidylate kinase n=1 Tax=Agrobacterium tumefac...   107   3e-22
UniRef50_A6T7F8 Thymidylate kinase n=62 Tax=Gammaproteobacteria ...   107   3e-22
UniRef50_Q1ICY2 Thymidylate kinase n=23 Tax=Gammaproteobacteria ...   107   3e-22
UniRef50_A4A8F5 Thymidylate kinase n=1 Tax=Congregibacter litora...   107   3e-22
UniRef50_C5AQT8 Thymidylate kinase n=14 Tax=Proteobacteria RepID...   107   3e-22
UniRef50_A1RYZ6 Thymidylate kinase n=1 Tax=Thermofilum pendens H...   107   4e-22
UniRef50_A0LF96 Thymidylate kinase n=1 Tax=Syntrophobacter fumar...   107   4e-22
UniRef50_C9RH19 Thymidylate kinase n=1 Tax=Methanocaldococcus vu...   107   4e-22
UniRef50_B9MNV9 Thymidylate kinase n=1 Tax=Anaerocellum thermoph...   106   5e-22
UniRef50_Q2STA4 Thymidylate kinase n=6 Tax=Bacteria RepID=KTHY_M...   106   5e-22
UniRef50_Q3SBA4 Thymidilate kinase n=1 Tax=uncultured euryarchae...   106   5e-22
UniRef50_Q98MV4 Thymidylate kinase n=3 Tax=Alphaproteobacteria R...   106   5e-22
UniRef50_B4DBR3 dTMP kinase n=1 Tax=Chthoniobacter flavus Ellin4...   106   6e-22
UniRef50_Q7UIM1 Thymidylate kinase n=1 Tax=Rhodopirellula baltic...   106   6e-22
UniRef50_B0MX01 Putative uncharacterized protein n=1 Tax=Alistip...   106   7e-22
UniRef50_D2RCC7 dTMP kinase n=1 Tax=Gardnerella vaginalis 409-05...   105   1e-21
UniRef50_A0RXT4 Thymidylate kinase n=1 Tax=Cenarchaeum symbiosum...   105   1e-21
UniRef50_Q4JAC4 Probable thymidylate kinase n=11 Tax=Sulfolobus ...   105   1e-21
UniRef50_Q0CE15 Thymidylate kinase n=1 Tax=Aspergillus terreus N...   105   1e-21
UniRef50_B2V7X0 Thymidylate kinase n=3 Tax=Sulfurihydrogenibium ...   105   1e-21
UniRef50_A5EXE3 Thymidylate kinase n=1 Tax=Dichelobacter nodosus...   105   1e-21
UniRef50_A1WSY9 Thymidylate kinase n=13 Tax=Proteobacteria RepID...   105   2e-21
UniRef50_A0B8K1 Thymidylate kinase n=1 Tax=Methanosaeta thermoph...   104   2e-21
UniRef50_C0QTF2 Thymidylate kinase n=1 Tax=Persephonella marina ...   104   2e-21
UniRef50_A1AVP9 Thymidylate kinase n=2 Tax=sulfur-oxidizing symb...   104   2e-21

>UniRef50_Q46843 Uncharacterized ATP-binding protein yghS n=43
           Tax=Enterobacteriaceae RepID=YGHS_ECOLI
          Length = 237

 Score =  246 bits (627), Expect = 6e-64,   Method: Composition-based stats.
 Identities = 237/237 (100%), Positives = 237/237 (100%)

Query: 1   MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWI 60
           MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWI
Sbjct: 1   MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWI 60

Query: 61  SQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFL 120
           SQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFL
Sbjct: 61  SQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFL 120

Query: 121 LITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDE 180
           LITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDE
Sbjct: 121 LITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDE 180

Query: 181 QTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
           QTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS
Sbjct: 181 QTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237


>UniRef50_C8WFA2 Putative uncharacterized protein n=3 Tax=Zymomonas mobilis
           RepID=C8WFA2_ZYMMN
          Length = 256

 Score =  227 bits (579), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 89/225 (39%), Positives = 127/225 (56%), Gaps = 1/225 (0%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
             ++IA+VGCDGSGKS+LT  L+  +    P +  YLG  SG +G  I Q+PV+G+    
Sbjct: 25  TGKLIALVGCDGSGKSSLTTDLIAAIQKYTPVKRYYLGLGSGDLGRKIGQIPVVGSWIEN 84

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVP 132
            L+ +A     K    PG +TALV+Y  S  R   + KM    + G  +ITDRYPQ E+ 
Sbjct: 85  LLKQRATTTRTKGKKIPGVMTALVVYFFSLRRFCSYLKMRRALKAGITVITDRYPQAEIA 144

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQL 192
           G   DGP L+    GN ++  L + E  LYQ MAS+ P L++RL +D +TA ARKPDH +
Sbjct: 145 GQ-CDGPGLSAAKAGNRFVSWLVRSEAALYQRMASFQPDLVLRLDVDPETAHARKPDHDI 203

Query: 193 AALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
            AL+ K  +   LTF GA +  +D   P   + +  +R +   L+
Sbjct: 204 EALRIKSEIMQHLTFGGAHMEVIDATRPYKAVWKDIVRLVQPYLT 248


>UniRef50_Q46844 Uncharacterized ATP-binding protein yghT n=39
           Tax=Enterobacteriaceae RepID=YGHT_ECOLI
          Length = 230

 Score =  225 bits (574), Expect = 7e-58,   Method: Composition-based stats.
 Identities = 80/229 (34%), Positives = 134/229 (58%), Gaps = 4/229 (1%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           + S    +IA++G DGSGKST+   L+  +      E ++LG+ +G +G  +++LP++G 
Sbjct: 1   MQSITPPLIAVIGSDGSGKSTVCEHLITVVEKYGAAERVHLGKQAGNVGRAVTKLPLMGK 60

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQ 128
              + +        +K    PG + ALVI      R  +FR ML   ++G +++TDRYPQ
Sbjct: 61  SLHKTIERNQVKTAKK---LPGPVPALVITAFVARRLLRFRHMLACRRRGLIVLTDRYPQ 117

Query: 129 VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP 188
            ++PG  +DG        G  ++  L  +E K + WMAS+ P L+I+L +D + A ARKP
Sbjct: 118 DQIPG-AYDGTVFPPNVEGGRFVSWLASQERKAFHWMASHKPDLVIKLNVDLEVACARKP 176

Query: 189 DHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
           DH+  +L  KIA+TPQLTF GA+++++D   P +++L  + +AI   ++
Sbjct: 177 DHKRESLARKIAITPQLTFGGAQLVDIDANQPLEQVLVDAEKAITDFMT 225


>UniRef50_P64573 Uncharacterized ATP-binding protein yghR n=42
           Tax=Enterobacteriaceae RepID=YGHR_ECOL6
          Length = 252

 Score =  204 bits (518), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 94/217 (43%), Positives = 131/217 (60%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA+VGCDG+GKSTLT  LV  L     TE  YLG  SG  G+ I +LP++G    R L 
Sbjct: 23  LIAVVGCDGTGKSTLTTDLVKSLQQHWQTERRYLGLLSGEDGDKIKRLPLVGVWLERRLA 82

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           +K++      +  P    A+++Y  S  R    RK+   +Q G L+++DR+PQ E+ GF 
Sbjct: 83  AKSSKTQSMKTKSPALWAAVIMYCFSLRRMANLRKVQRLAQSGVLVVSDRFPQAEISGFY 142

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
           +DGP +            L QRE +LYQ MA Y P L+IRLGID +TA +RKPDH  A L
Sbjct: 143 YDGPGIGVERATGKISMFLAQRERRLYQQMAQYRPELIIRLGIDIETAISRKPDHDYAEL 202

Query: 196 QEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAI 232
           Q+KI V  ++ +NG KILE+D R P  E+L+ + +A+
Sbjct: 203 QDKIGVMSKIGYNGTKILEIDSRAPYSEVLEQAQKAV 239


>UniRef50_Q5NMW8 Conserved predicted protein with nucleoside triphosphate hydrolase
           domain n=3 Tax=Zymomonas mobilis RepID=Q5NMW8_ZYMMO
          Length = 240

 Score =  195 bits (496), Expect = 8e-49,   Method: Composition-based stats.
 Identities = 84/227 (37%), Positives = 134/227 (59%), Gaps = 3/227 (1%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           +    +IA+VG DGSGK+T+   L+  L    PT   +LG+ +G  G  I+++P +G   
Sbjct: 9   NRSAPLIALVGADGSGKTTVGQELLEWLQTMRPTAFCHLGKQTGNWGRAIARMPFVGRKL 68

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVE 130
            + + ++++   ++     G   ++VI+ LS  R ++F +M    ++GF+++TDRYPQ  
Sbjct: 69  DKQVIARSSKARDEKG--AGATVSIVIFALSMRRVFRFLRMRRLHRKGFMILTDRYPQAV 126

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH 190
           VPG   DGP L          + L  RE  LY WMASY P ++IRL +D +TA  RKPDH
Sbjct: 127 VPG-PMDGPGLVARNPKGMIARFLTGREQALYDWMASYKPDIVIRLNVDLETALKRKPDH 185

Query: 191 QLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
           + A+L+ K+   P+L+FNGA IL+LD R P D+++  +  AI   ++
Sbjct: 186 RPASLERKVRDVPRLSFNGAPILDLDSREPLDQVIGKAKAAILDVIA 232


>UniRef50_Q2LPR0 Hypothetical cytosolic protein n=1 Tax=Syntrophus aciditrophicus SB
           RepID=Q2LPR0_SYNAS
          Length = 487

 Score =  176 bits (445), Expect = 6e-43,   Method: Composition-based stats.
 Identities = 55/239 (23%), Positives = 97/239 (40%), Gaps = 11/239 (4%)

Query: 3   QRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLG-QSSGRIGEWIS 61
           +R      +    +IAIVG DG+GK+T+   +   L  +     +++G  +  R     S
Sbjct: 255 RRTFKRRVTHGGLLIAIVGGDGAGKTTVIEEVHKWLGRKFDVMKLHMGKPARSRTTILGS 314

Query: 62  QLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLL 121
               IG   G Y     A ++ + +  PG    + +  L+  R   + K    +  G L+
Sbjct: 315 GFLKIGTMLGLY--PATADLYAEEAEFPGYPFLIRMVFLAYDRYLTYLKARRFASNGGLV 372

Query: 122 ITDRYPQVEVPGFRFDGPQLA----KTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLG 177
           I DRY   ++     DGP+           N ++  L + E   Y+ M S  P LLI L 
Sbjct: 373 ICDRYFLADL--LTMDGPRCKMMAKAFNRSNFFMNWLIRIEASCYEKMMS--PDLLIVLR 428

Query: 178 IDEQTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
           ++ + A  RK D    +++ +     +  ++      +D   P +E+L      I   L
Sbjct: 429 LNPEIAVQRKTDETAVSVRARSTSIWEYDWSKTSACVVDSSRPKEEVLAQVQSLIWRYL 487


>UniRef50_C5KB73 Thymidylate kinase, putative n=2 Tax=Perkinsus marinus ATCC 50983
           RepID=C5KB73_9ALVE
          Length = 233

 Score =  158 bits (399), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 45/230 (19%), Positives = 76/230 (33%), Gaps = 40/230 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
              I + G D SGKST    +   L  R   E + +G        +  +   IG     Y
Sbjct: 4   GAFIVLEGLDRSGKSTQLRRISEALRQRTGKEVVEMG--------FPRRSSAIGKMLDTY 55

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           LR  ++ + ++           V  L S  R     +ML     G  ++ DRY    V  
Sbjct: 56  LRDSSSKMRDEA----------VHLLFSANRWEAMSEMLSHLAAGRHIVCDRYIFSGVAY 105

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----KPD 189
               G             +  +  ++ L        P L++ L +  + A  R    +  
Sbjct: 106 TAMKGTV---------DFEWCKSVDVGL------PKPDLVVFLDLSPEAAAKRGAYGEER 150

Query: 190 HQLAALQEKIAVTPQLTFNGAKILELDGRHPADEI---LQASLRAIHAAL 236
           ++   LQ K+                D   PA+E+   +  +  A+  AL
Sbjct: 151 YEKEDLQMKVRTMYTKFEKEPFWRIFDADRPAEEVTRTVTDAAVAVAQAL 200


>UniRef50_A6S4P1 Putative uncharacterized protein n=2 Tax=Sclerotiniaceae
           RepID=A6S4P1_BOTFB
          Length = 242

 Score =  158 bits (399), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 38/238 (15%), Positives = 79/238 (33%), Gaps = 42/238 (17%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
           +    I I G D +GK+T    L ++L A               +  +  +   IG    
Sbjct: 19  SRGSFILIEGLDRAGKTTQVKKLCDKLYASGRNVK---------LMRFPDRTTAIGQQIN 69

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEV 131
            YL+S                   +  L S  R  K +++     QG+ ++ DRY     
Sbjct: 70  SYLQSST-----------ALPDQSIHLLFSANRWEKAQEIRDLIAQGYTIVCDRYYYS-- 116

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK---- 187
            G  +   + +  +  +  ++  +  E+ L       +P  +I L ++ + A  R     
Sbjct: 117 -GMIYTSSKYSIDSPNHLSLEWCKNPEIGL------PMPDRVIFLDLEPEEAEKRGGYGD 169

Query: 188 PDHQLAALQEKIAV---------TPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
             ++   +Q ++            P        +  +D     DE+ +    A+   +
Sbjct: 170 EKYETREMQRRVRNGFLSLQNSAVPGFEQEQRIMKAIDAGDGLDEVAEKIWHAVKDIV 227


>UniRef50_C6TJ88 Putative uncharacterized protein n=1 Tax=Glycine max
           RepID=C6TJ88_SOYBN
          Length = 299

 Score =  156 bits (394), Expect = 6e-37,   Method: Composition-based stats.
 Identities = 38/231 (16%), Positives = 79/231 (34%), Gaps = 41/231 (17%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           ++   ++ + G D SGKS+  + LV  L  +           S  +  +  +   +G   
Sbjct: 55  ASRGALVVLEGLDRSGKSSQCSRLVPFLEGQGI---------SAELWRFPDRTTNVGQMI 105

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVE 130
             YL           +         +  L S  R  K   M  K + G  LI DRY    
Sbjct: 106 SAYL-----------TNTSQLDDHTIHLLFSANRWEKRSLMESKLKTGTTLIVDRYSYS- 153

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---- 186
                     +A ++      +  +  E+ L        P +++ L I  + A  R    
Sbjct: 154 ---------GVAFSSAKGLDFEWCKVPEIGL------PAPDVVVYLDISPEKAAERGGYG 198

Query: 187 KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
              ++    Q+K+A   ++  +     ++D   P +++ +     +   ++
Sbjct: 199 GERYEKLEFQKKVADWYKVLHD-VSWKDVDACQPIEDVEKQLQEIVLDCVT 248


>UniRef50_Q0WW55 Thymidylate kinase-like protein n=22 Tax=Eukaryota
           RepID=Q0WW55_ARATH
          Length = 263

 Score =  153 bits (385), Expect = 6e-36,   Method: Composition-based stats.
 Identities = 42/227 (18%), Positives = 76/227 (33%), Gaps = 41/227 (18%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
             +I + G D SGKST  A L++ L                 +  +  +   +G     Y
Sbjct: 59  GALIVLEGLDRSGKSTQCAKLLSFLNGLGH---------PTELWRFPDRETSVGQMISAY 109

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           L +K+                 +  L S  R  K   M  K + G  LI DRY       
Sbjct: 110 LSNKS-----------QLDDHTIHLLFSANRWEKRSLMEEKLKTGTTLIVDRYSYS---- 154

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK----PD 189
                  +A ++     I+  +  E+ L        P  ++ L I  + A  R       
Sbjct: 155 ------GVAFSSAKGLDIEWCKAPEIGL------LAPDSVLYLDISPERAAERGGYGDER 202

Query: 190 HQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
           ++    Q+K+A   Q T   +    ++     +E+ +   + +   +
Sbjct: 203 YERVEFQKKVADFYQ-TLGDSSWKIINASDAMEEVEKKIQQVVLDQV 248


>UniRef50_A8Q2K3 Putative uncharacterized protein n=1 Tax=Malassezia globosa CBS
           7966 RepID=A8Q2K3_MALGO
          Length = 520

 Score =  151 bits (380), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 49/238 (20%), Positives = 80/238 (33%), Gaps = 48/238 (20%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
            N      I + G D SGKST    LV  L  R             R+ ++  +   IG+
Sbjct: 306 TNGERGVFIVVEGLDRSGKSTQVDRLVQTLGPR------------ARLVKFPERTTPIGS 353

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQ 128
               YL+++                  V  L S  R      ++   + G  +I DRY  
Sbjct: 354 MIHSYLKNQT-----------DACDQTVHLLFSANRWELLSSIVQSLRDGQHVICDRYIF 402

Query: 129 VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-- 186
                       +A T      +      ++ L       +P L + L +DE TA  R  
Sbjct: 403 S----------GMAYTHAKGLDLAWCTAPDVGL------PVPDLTLFLDLDESTATKRAA 446

Query: 187 --KPDHQLAALQEKIA-----VTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
             +  ++  A Q  +      V   +  +GA+   LD     D++ QA    +   +S
Sbjct: 447 YGEERYERRAFQRLVRHAFENVEQLMLRSGARWERLDASGTLDDVWQAVHAQVQEVVS 504


>UniRef50_B0EQM5 Thymidylate kinase, putative n=2 Tax=Entamoeba RepID=B0EQM5_ENTDI
          Length = 210

 Score =  150 bits (378), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 36/233 (15%), Positives = 69/233 (29%), Gaps = 42/233 (18%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           +N+    +I + G D SGKS+    +   L  +                 +  +   IG 
Sbjct: 1   MNTNRGLLIVLEGIDQSGKSSAAQRVCEMLEKKGIQSIKQP---------FPDRSTDIGK 51

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQ 128
               +L  K                 +V  L S  R    +K+    ++G  +I DRY  
Sbjct: 52  LIDEFLHGK------------NLPQQVVHLLYSANRWEVAQKIKETLEKGITIICDRYAF 99

Query: 129 VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP 188
                       +  +       +     +  L        P ++  L +  + A  R+ 
Sbjct: 100 S----------GIVYSIANGLDERWCNSADSGL------PKPDIVFFLELSLEDAEQRRK 143

Query: 189 -----DHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                 ++    Q K+    +   +  K   +D R   +E+       I   L
Sbjct: 144 TMKTDRYENIKFQSKVKCEYEKFKDSMKWTCIDARQSKEEVALEITSIIEQQL 196


>UniRef50_P36590 Thymidylate kinase n=2 Tax=Ascomycota RepID=KTHY_SCHPO
          Length = 210

 Score =  148 bits (374), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 39/231 (16%), Positives = 76/231 (32%), Gaps = 45/231 (19%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
               R+I I G D SGKST    LV++L ++              + ++  +   IG   
Sbjct: 4   QNRGRLIVIEGLDRSGKSTQCQLLVDKLISQ---------HEKAELFKFPDRTTAIGKKI 54

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVE 130
             YL+                   ++  L S  R    + +  +  +G   I DRY    
Sbjct: 55  DDYLK-----------ESVQLNDQVIHLLFSANRWETIQYIYEQINKGVTCILDRYAFSG 103

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---- 186
           +                    +  +  +  L        P L+I L +D + A  R    
Sbjct: 104 IAFSA----------AKGLDWEWCKSPDRGL------PRPDLVIFLNVDPRIAATRGQYG 147

Query: 187 KPDHQLAALQEKI-----AVTPQLTFNGAKILELDGRHPADEILQASLRAI 232
           +  ++   +QEK+      +  +    G + + LD     +++    +  +
Sbjct: 148 EERYEKIEMQEKVLKNFQRLQKEFREEGLEFITLDASSSLEDVHSQIVDLV 198


>UniRef50_Q3B752 Zgc:123174 n=5 Tax=root RepID=Q3B752_DANRE
          Length = 212

 Score =  148 bits (374), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 37/235 (15%), Positives = 69/235 (29%), Gaps = 41/235 (17%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           ++     +I + G D +GK+T    LV  +              +  I  +  +   IG 
Sbjct: 1   MSCRRGALIVLEGVDRAGKTTQCQKLVQAIQQSG---------RAAEIMRFPDRTTKIGQ 51

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQ 128
               YL  K+                 V  L S  R      M  K ++G  L+ DRY  
Sbjct: 52  LISSYLEKKS-----------NLEDHTVHLLFSANRWEMVPVMKQKLEEGINLVVDRYAF 100

Query: 129 VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-- 186
             V                   ++     ++ L        P L++ L ++   A  R  
Sbjct: 101 SGVAFTS---------AKPGFSLEWCMNPDVGL------PKPDLVMFLQLNPNVAANRGE 145

Query: 187 --KPDHQLAALQEKIAVTPQLTFNGAK--ILELDGRHPADEILQASLRAIHAALS 237
                ++ +A Q  +    +            +D     +E+ +         +S
Sbjct: 146 YGNERYETSAFQRTVQQRFEELMQDTSINWKVIDAARTIEEVHKDIKDLSENIIS 200


>UniRef50_B6YSZ4 Probable thymidylate kinase n=5 Tax=Thermococcaceae
           RepID=KTHY_THEON
          Length = 205

 Score =  148 bits (374), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 39/230 (16%), Positives = 75/230 (32%), Gaps = 38/230 (16%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I I G DG+GKST    L      +     +    +    G+ I +L + G   G    
Sbjct: 2   FIVIEGIDGAGKSTQARLLAEWFKKKGYDVVLTKEPTDTAFGKLIRRLVLTGGKEGIIDG 61

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
           ++ +H  E               L +  RA    K +    + G ++I+DRY    +   
Sbjct: 62  ARISHEAE-------------ALLFAADRAEHVHKLIKPSLKTGKIVISDRYFYSSLAYQ 108

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH---- 190
                           ++ L               P L+I L +  + +  R        
Sbjct: 109 ----------WARGLDLEWLIDLNRFAV------RPDLVILLDLPVKESMKRINGRSIKT 152

Query: 191 ---QLAALQEKIAVTP-QLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
              ++A LQ+K+     +L     ++  ++     ++I    +  +   L
Sbjct: 153 EFDKIAELQKKVRENYLKLAERFPEMRIVNALASVEDIHNDIVALVEHEL 202


>UniRef50_B6QFH6 Thymidylate kinase n=13 Tax=Eurotiomycetidae RepID=B6QFH6_PENMQ
          Length = 238

 Score =  147 bits (370), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 38/235 (16%), Positives = 68/235 (28%), Gaps = 40/235 (17%)

Query: 7   SIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVI 66
           +I       ++ + G D +GKS+    L   L                    +  +   I
Sbjct: 6   AIDKEKRGALVVVEGLDRAGKSSQCELLYKSLLGMNYKAKYI---------RFPDRSTPI 56

Query: 67  GAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRY 126
           G     YLR ++                 +  L S  R    + +      G  +I DRY
Sbjct: 57  GKQIDSYLRGES-----------QLDDHSIHLLFSANRWEVAQSIQKDIADGTTVIVDRY 105

Query: 127 PQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR 186
                      G         N  +    Q E+ L        P L + L I  + A  R
Sbjct: 106 SYSGAVYSAAKG-------NPNLSLHWAWQPEVGL------PRPDLCLFLSISPEEAAKR 152

Query: 187 K----PDHQLAALQEKIAVTPQLTFN---GAKILELDGRHPADEILQASLRAIHA 234
                  ++  ++Q+++        +     +I  +D     DE+    L  +  
Sbjct: 153 GGYGVERYETDSMQKRVRDLFLSLLDLPHNDEICVIDAGQSVDEVALDILEPVLE 207


>UniRef50_B0D7L7 Predicted protein n=2 Tax=Agaricales RepID=B0D7L7_LACBS
          Length = 228

 Score =  146 bits (369), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 40/237 (16%), Positives = 72/237 (30%), Gaps = 41/237 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
              I I G D SGK+T T+ L   L A               + ++  +  VIG     Y
Sbjct: 3   APFIVIEGLDRSGKTTQTSLLHTRLEAEGIQAK---------LMKFPDRTTVIGQMIDSY 53

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           LRS +                ++  L S  R      +    + G  +I DRY    +  
Sbjct: 54  LRSDSE-----------LDDHVIHLLFSANRWELASYITQLLEAGTPIICDRYAFSGIAF 102

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----KPD 189
               G   +  +      +  R  ++ L        P L++ L I  + A  R    +  
Sbjct: 103 SASKGIPSSTPSPK-LPYEWCRSPDIGL------PAPDLVLFLDIAPERAKLRGGYGEER 155

Query: 190 HQLAALQEKIAVTPQLTFN----------GAKILELDGRHPADEILQASLRAIHAAL 236
           ++   LQ ++    Q   +              + +D       +       +   +
Sbjct: 156 YEKEELQARVRGIFQRLGSEMQNETQRPVRPNWVTVDAGRERKVVANEVWSLVEPLV 212


>UniRef50_Q4P9K7 Putative uncharacterized protein n=2 Tax=Fungi/Metazoa group
           RepID=Q4P9K7_USTMA
          Length = 1208

 Score =  145 bits (365), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 42/235 (17%), Positives = 71/235 (30%), Gaps = 50/235 (21%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
                I + G D +GKST    L   L A+                ++  +   IG    
Sbjct: 424 KRGFFIVVEGLDRAGKSTQVERLAAHLQAKAV--------------KFPERTTAIGQMIN 469

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEV 131
            YL           +         +  L S  R      +    + G  ++ DRY     
Sbjct: 470 SYL-----------AQTSDLDDQAIHLLFSANRWECVASLHRTLEAGESIVCDRYAFS-- 516

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----- 186
                    +A +          R  ++ L       LP L + L +D   A AR     
Sbjct: 517 --------GIAYSVAKGLSYDWCRNPDVGL------PLPDLTLFLDLDANAAAARGGYGE 562

Query: 187 ----KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
               K D Q    +    V+  +  +G + + +D     D++     +A+H   S
Sbjct: 563 ERYEKLDFQAKVREAFTRVSQDVRTHGGRWVTIDASKTLDQVTDDMQKAVHRVTS 617


>UniRef50_B7Q0D8 Thymidylate kinase, putative n=1 Tax=Ixodes scapularis
           RepID=B7Q0D8_IXOSC
          Length = 214

 Score =  145 bits (364), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 38/232 (16%), Positives = 75/232 (32%), Gaps = 44/232 (18%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
              +   GCD +GK+T    L   L+                   + ++    G     Y
Sbjct: 7   GLFVVFEGCDRTGKTTQIKLLSESLSKLGH---------KTETVAFPNRSTTTGTLLDSY 57

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           L++ +  + +            V  L S  R      +L    +   +I DRY    V  
Sbjct: 58  LKA-STDLDDHA----------VHLLFSANRWEAAPSLLSTLARNTTVIADRYAYSGVAF 106

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----KPD 189
                         +   +  +Q ++ L        P L++ + +  +T  AR    +  
Sbjct: 107 SA----------AKSLDFRWCQQCDVGL------PEPDLVLYMSVPPETLAARGGFGEER 150

Query: 190 HQLAALQEKIAVTP----QLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
           ++ ++ QEK+         L   G + +E+D      E+       +  AL+
Sbjct: 151 YENSSFQEKVRANYNHLASLEAKGGRWIEVDCSKSVQEVHHIIESVVLEALT 202


>UniRef50_C6A0S1 Probable thymidylate kinase n=4 Tax=Thermococcus RepID=KTHY_THESM
          Length = 210

 Score =  145 bits (364), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 40/230 (17%), Positives = 73/230 (31%), Gaps = 38/230 (16%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G DG+GKST    L      R     +    +    G+ I +L +IG   G    
Sbjct: 4   FIVLEGIDGAGKSTQAKMLAKWFENRGYEVVLTKEPTDTAFGKLIRRLVLIGGKEGIIDG 63

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
           ++ +   E               L +  RA   +K +    + G ++I+DRY    +   
Sbjct: 64  ARISKEAE-------------ALLFAADRAEHVKKLIEPSIKAGKVVISDRYFYSSLAYQ 110

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLA- 193
                           +  L            +    L+I L +  + +  R     +  
Sbjct: 111 ----------WARGLDLNWLINLNA------FAPRADLVILLDLPVKESINRINGRSIRS 154

Query: 194 ------ALQEKIAVTP-QLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                  LQ+K+     +L     +I  ++   P ++I       I   L
Sbjct: 155 EFDKIVELQKKVRKNYLKLAEKFNEIRIINALAPVEDIHNDITALIEHEL 204


>UniRef50_Q67JB0 Thymidylate kinase n=1 Tax=Symbiobacterium thermophilum
           RepID=KTHY_SYMTH
          Length = 214

 Score =  144 bits (362), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 41/231 (17%), Positives = 74/231 (32%), Gaps = 41/231 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I+  G DGSGKST    L+  L  +                   ++ P  G P    +R
Sbjct: 4   FISFEGVDGSGKSTQIRLLLQYLDEQSVPYVF-------------TREPG-GTPIAEQIR 49

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEVPGF 134
                   +     G        L +  RA    R +    ++G ++I DR+    +   
Sbjct: 50  RVLLDPANR-----GMSVITEALLFAAARAEHVSRTIRPALEEGKVVICDRFVDSSL--- 101

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
            + G        G   ++ L Q          +  P   I L +  + A AR+   +   
Sbjct: 102 VYQG------VAGGLPVEFLTQINEMA---TGALRPHRTIVLDLAPEVALARRTGEEADR 152

Query: 195 LQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAAL 236
           ++ +     QL   G          ++  +D     +E+ +   R +   L
Sbjct: 153 IERQSREYHQLVREGYLDLARAEPRRVKVVDASRSVEEVQKDIRRLVEEVL 203


>UniRef50_A5N3T4 Tmk n=32 Tax=Bacteria RepID=A5N3T4_CLOK5
          Length = 228

 Score =  144 bits (362), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 39/248 (15%), Positives = 82/248 (33%), Gaps = 41/248 (16%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           + S   ++I I GCDGSGK+T T  L N L             +       + ++ + G 
Sbjct: 1   MESLKGKLIVIEGCDGSGKATQTRKLYNRLLDEKYNVKKVEYPNYNSESSALVKMYLNG- 59

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYP 127
                         +    P      +        R   ++ +     + G ++++DRY 
Sbjct: 60  --------------DFGENPEDVSAYVASTFYGVDRFASYKTQWKKFYEGGGIVLSDRYT 105

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQ------ 181
                       ++      + ++K L   E  +++     +P  +I L +  +      
Sbjct: 106 TSN---MVHQASKIDNIEEKDKFLKWLWDFEFNIFK---LPVPDCVIFLDMPPEYSKNLM 159

Query: 182 -------TAFARKPDHQ------LAALQEKIAVTPQLTFNGAKILELDGRHPADEILQAS 228
                  T  A+K  H+      + +    + V  +  +N    +E D  +  +EI +  
Sbjct: 160 IERNNKFTGNAKKDIHESNYEYLINSYNNAVYVADKYGWNKISCIENDRINTVNEIHKNI 219

Query: 229 LRAIHAAL 236
              +   L
Sbjct: 220 YSLVKYIL 227


>UniRef50_C0EEB4 Putative uncharacterized protein n=1 Tax=Clostridium methylpentosum
           DSM 5476 RepID=C0EEB4_9CLOT
          Length = 205

 Score =  143 bits (359), Expect = 6e-33,   Method: Composition-based stats.
 Identities = 47/238 (19%), Positives = 68/238 (28%), Gaps = 51/238 (21%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           + I   G DGSGK T    L  E   R          +    G  I        P     
Sbjct: 3   KFIVFEGLDGSGKGTQIRLLCEEFKRRGEAFQQTAEPTFSVTGGAIRDALNGNHPRH--- 59

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYK----FRKMLCKSQQGFLLITDRYPQVE 130
                              A +  L    R Y     F  +     QG  +I DRY    
Sbjct: 60  ------------------PAELAALFLTDRIYHNTGKFDGIELLLSQGKHVICDRYYYSS 101

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---- 186
              F + G            ++ + +  L          P L I L +D Q + AR    
Sbjct: 102 ---FAYQGT--------GCDMQWVMEMNLNCPN---IRKPDLCIYLDVDPQRSKARVDGA 147

Query: 187 --------KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                   +   Q+ A++ K     +L      I+ +D   P DE+      A+   L
Sbjct: 148 NKSLEIFEQDIAQITAIRNKFMKAFELLGERETIVLIDADRPVDEVAADVWDAVKRIL 205


>UniRef50_C3ZEC2 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3ZEC2_BRAFL
          Length = 215

 Score =  143 bits (359), Expect = 7e-33,   Method: Composition-based stats.
 Identities = 41/233 (17%), Positives = 74/233 (31%), Gaps = 41/233 (17%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           + S    +I + G D SGK+T    LV  L                 +  +  +   IG+
Sbjct: 1   MASARGALIVLEGVDHSGKTTQCMKLVEALKKHG---------QKAELIRFPDRTTAIGS 51

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQ 128
               YL +K                  +  L S  R     +M     +G  LI DRY  
Sbjct: 52  VINDYLGNKCE-----------LHDFAIHLLFSANRWEAVPRMEKLLSEGTSLIVDRYAY 100

Query: 129 VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-- 186
             V                   ++ L+  ++ L        P L++ L +  + A  R  
Sbjct: 101 SGVAFTA----------AKGLDMRRLQHSDIGL------PRPDLVMYLTLPPEEAAKRSE 144

Query: 187 --KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
                ++    Q+K+A   ++         L+     +E+    L+    A++
Sbjct: 145 YGGERYEQTDFQKKVAENFKVLQEDD-WKILNANQTIEELHTHILQLAKEAIT 196


>UniRef50_B3LDF8 Thymidylate kinase, putative n=5 Tax=Plasmodium RepID=B3LDF8_PLAKH
          Length = 219

 Score =  142 bits (357), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 38/228 (16%), Positives = 71/228 (31%), Gaps = 39/228 (17%)

Query: 10  NSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAP 69
                + I   G D SGKST +  LV  L  +   E  +L         + ++    G  
Sbjct: 12  TKKKGKFIVFEGLDRSGKSTQSKLLVEHLRRK-NVEVNHLC--------FPNRETPTGQI 62

Query: 70  FGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQV 129
             +YL+ +    +E            +  L S  R     ++     +G  ++ DRY   
Sbjct: 63  IAKYLKMQNDMTNE-----------TIHLLFSANRWELMGEIKRLLSKGVWVVCDRYAYS 111

Query: 130 EVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR--- 186
            V            +             +  L        P ++  L +    A  R   
Sbjct: 112 GVAY---------SSGALKLSKTWCMNPDQGL------IKPDVVFYLNVPPNYAQQRSEY 156

Query: 187 -KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIH 233
            +  ++   +Q++I    +        + LDG    ++I Q  +  I 
Sbjct: 157 GEEIYEKVEVQKRIYEAYKNFSQEDYWINLDGTKNINDIHQDVVNEIT 204


>UniRef50_B5IF40 Thymidylate kinase n=2 Tax=Aciduliprofundum boonei T469
           RepID=B5IF40_9EURY
          Length = 197

 Score =  141 bits (356), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 38/227 (16%), Positives = 74/227 (32%), Gaps = 37/227 (16%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G DGSGKST+   +   L++      +    ++  +G+ + +             
Sbjct: 2   FIVFEGIDGSGKSTIAKRIAEHLSSLGHKIFLTEEPTTTWMGKDVRR------------- 48

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                     +            L    RA     +    + G ++I+DRY       F 
Sbjct: 49  ----------AIEEEKNPLSQALLFFADRAEHVEAIKKNLEDGKIVISDRYVYST---FA 95

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF----AR--KPD 189
           + G Q+ K    +  +K L      +Y+ M    P ++I L I+ +        R  K  
Sbjct: 96  YQGAQMEKLMPLDKALKWLE----GVYEPMR-LDPDMVILLKIEPRRGLDFVNTRDFKEK 150

Query: 190 HQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
            +     E++        +      +D     +E+     + I A +
Sbjct: 151 FEREEFLERVQDIYMALADKYGFFVVDSNRNLNEVYDDVRKIIDARI 197


>UniRef50_D2A7H7 Putative ATP-binding protein yghT n=3 Tax=Enterobacteriaceae
           RepID=D2A7H7_SHIF2
          Length = 131

 Score =  141 bits (355), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 50/127 (39%), Positives = 82/127 (64%), Gaps = 1/127 (0%)

Query: 111 MLCKSQQGFLLITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLP 170
           ML   ++G +++TDRYPQ ++PG  +DG        G  ++  L  +E K + WMAS+ P
Sbjct: 1   MLACRRRGLIVLTDRYPQDQIPG-AYDGTVFPPNVEGGRFVSWLASQERKAFHWMASHKP 59

Query: 171 VLLIRLGIDEQTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLR 230
            L+I+L +D + A ARKPDH+  +L  KIA+TPQLTF GA+++++D   P +++L  + +
Sbjct: 60  DLVIKLNVDLEVACARKPDHKRESLARKIAITPQLTFGGAQLVDIDANQPLEQVLVDAEK 119

Query: 231 AIHAALS 237
           AI   ++
Sbjct: 120 AITDFMT 126


>UniRef50_Q5KK13 Thymidylate kinase, putative n=2 Tax=Filobasidiella neoformans
           RepID=Q5KK13_CRYNE
          Length = 217

 Score =  141 bits (354), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 39/238 (16%), Positives = 70/238 (29%), Gaps = 47/238 (19%)

Query: 10  NSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAP 69
            ST    I   G D  GKST    LV  L  +     +          ++  +   IG  
Sbjct: 3   TSTRGAFIVFEGLDRCGKSTQVDRLVQRLERQGHRARLQ---------KFPERTTQIGKM 53

Query: 70  FGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQV 129
              YL+SK                  +  L S  R      +      G  +I DRY   
Sbjct: 54  IDAYLQSKTE-----------IDDHAIHLLFSANRWECSAAIRRDLANGITVIADRYAFS 102

Query: 130 EVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR--- 186
            +                          +  L       LP + + L +  +TA  R   
Sbjct: 103 GIAFSA----------AKGLPFDFCLHPDAGL------PLPDVTLYLTLPPETAAKRSAY 146

Query: 187 -KPDHQLAALQEKIAVTPQLTFNG-------AKILELDGRHPADEILQASLRAIHAAL 236
            +  ++  ++Q+ +    +L  N         K +E++     +++ +     I   +
Sbjct: 147 GEERYESVSIQQAVRQQFKLVANEIKKRHGADKWIEIEADGTFEDVEERIWSQISDVV 204


>UniRef50_B5Y400 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
           RepID=B5Y400_PHATR
          Length = 245

 Score =  141 bits (354), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 31/235 (13%), Positives = 66/235 (28%), Gaps = 39/235 (16%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
           +    + + G D  GK+T +  L+  L A                  +  +    G    
Sbjct: 9   SRGAFVVLEGVDRCGKTTQSGLLLKRLLAAGIA---------ACSMRFPDRTTATGKIID 59

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEV 131
           +YL+S                   +  L S  R      +    Q G  ++ DRY     
Sbjct: 60  QYLQSSQ-----------NLDDRAIHLLFSANRWESADALTAHLQAGTTVLCDRYAYS-- 106

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----- 186
            G  F   ++ K       +   +  +  L        P  +I L + +  A  R     
Sbjct: 107 -GVAFSASKIDKKGNSLLSLDWCQAPDQGL------PAPDCVIFLDLSQAEAEQRGGYGG 159

Query: 187 ---KPDHQLAALQEKIAVTPQLTFNGAK--ILELDGRHPADEILQASLRAIHAAL 236
              +       ++ +      +     +     +D     +++     +A+   +
Sbjct: 160 ERYEKKEMQIRVRHRFGDLEAIDKASGRVAWKFIDAAQSVEQVENDIWKAVEETI 214


>UniRef50_A2QUJ3 Catalytic activity: ATP + thymidine 5'-phosphate <=> ADP +
           thymidine 5'-diphosphate n=11 Tax=Eurotiomycetidae
           RepID=A2QUJ3_ASPNC
          Length = 224

 Score =  141 bits (354), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 37/235 (15%), Positives = 71/235 (30%), Gaps = 42/235 (17%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           +    +I + G D +GKS+   SL  +L     +              +  +   IG   
Sbjct: 8   ARRGALIVVEGLDRAGKSSQCESLHQKLQDLGHSVKYI---------RFPDRTTPIGKLI 58

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVE 130
             YLR ++                 +  L S  R    R +      G  +I DRY    
Sbjct: 59  DGYLRGQS-----------QLDDHSIHLLFSANRWEIARAIEEDIAAGITVIVDRY---- 103

Query: 131 VPGFRFDGPQLAKTTGG-NGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK-- 187
                + G   +         ++     E+ L        P L + L I    A  R   
Sbjct: 104 ----SYSGAVYSAAKANPTLSLEWAWTPEIGL------PQPDLCLFLSIAPDEAAKRGGF 153

Query: 188 --PDHQLAALQEKIAVTPQLTFNGAK---ILELDGRHPADEILQASLRAIHAALS 237
               ++   +Q ++    Q  F   +   I  +D     + +     +++   ++
Sbjct: 154 GAERYENETMQSRVRELFQTIFRVQRSGDIRVIDAGRSFEAVSVDIEKSVVDCIA 208


>UniRef50_Q17LP5 Thymidylate kinase, putative n=4 Tax=Culicidae RepID=Q17LP5_AEDAE
          Length = 249

 Score =  140 bits (353), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 42/236 (17%), Positives = 73/236 (30%), Gaps = 41/236 (17%)

Query: 5   NMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLP 64
           NMSII      +I + GCD +GK+T    +V  L +                  +  +  
Sbjct: 39  NMSIIQKRGA-LIVLEGCDRAGKTTQCKRIVESLNSAGHKAKF---------MNFPDRST 88

Query: 65  VIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITD 124
             GA    YL SK     E            +  L +  R     +M    + G  LI D
Sbjct: 89  QFGALINSYLTSKDNFTDEA-----------IHLLFTLNRWEAKNEMERLLRSGVTLIVD 137

Query: 125 RYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF 184
           RY    V                   +   +  E  L        P L++ L +  +   
Sbjct: 138 RYSYSGVAFSA----------AKGLNMDWCKAPETGL------PKPDLVLLLTLTAEAMA 181

Query: 185 AR----KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
            R    +  +++  LQ+K+        + +    +D     D +       +  ++
Sbjct: 182 KRGGFGQERYEVPELQKKVMEKFHTLKDDSYWKVVDADKKEDALSLELCEMVLDSM 237


>UniRef50_C1BRK2 Thymidylate kinase n=1 Tax=Caligus rogercresseyi RepID=C1BRK2_9MAXI
          Length = 216

 Score =  140 bits (353), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 43/239 (17%), Positives = 69/239 (28%), Gaps = 46/239 (19%)

Query: 6   MSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPV 65
           MS         I + GCD SGK+T+   L +   +       +  + S   G  I+    
Sbjct: 1   MSSSAVKRGAFIVLEGCDRSGKTTIAKRLSD---SPGFEFFRFPDRDSPLTGSLINSFLT 57

Query: 66  IGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDR 125
            G P                         L+  L S  R  K   ML     G  +I DR
Sbjct: 58  GGTPMSSQ---------------------LIHLLFSANRWEKVPSMLSVLSAGKNIICDR 96

Query: 126 YPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA 185
           Y    +            ++            +  L        P L+I L +  + A  
Sbjct: 97  YAYSGIAY---------SSSKPGMDFDWCAGPDNGL------PTPDLVIFLDVSPEQALK 141

Query: 186 R----KPDHQLAALQEKIAVTP--QLTFNGAKILELDG-RHPADEILQASLRAIHAALS 237
           R    +  ++    Q K+      +L   G +   +       D+   A    +   LS
Sbjct: 142 RGGFGEEVYEKVGFQAKVRDIYTTKLVGKGGEWKWISTDGKTLDDTYCAVKTLVDEVLS 200


>UniRef50_B8D357 Thymidylate kinase n=1 Tax=Desulfurococcus kamchatkensis 1221n
           RepID=B8D357_DESK1
          Length = 206

 Score =  139 bits (350), Expect = 8e-32,   Method: Composition-based stats.
 Identities = 34/229 (14%), Positives = 66/229 (28%), Gaps = 47/229 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G DG+GK+T+   LV +L++R          +   I   I               
Sbjct: 7   FIVLEGLDGAGKTTVARRLVEDLSSRGIPASYTYEPTDSEIVRVI--------------- 51

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKM-LCKSQQGFLLITDRYPQVEVPGF 134
                   K +        +     +  R    +        +G  +I+DRY    V   
Sbjct: 52  --------KSTYNNLRDAYIDALAFALDRLIHVKNWVKPLLDKGVTVISDRYFYSSVAYQ 103

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK------- 187
              G         N +                   P + I L I+ +   +RK       
Sbjct: 104 SASGAPFEWVIEVNKFAM----------------KPDVAIYLDIEPEEGLSRKHMHTSRF 147

Query: 188 PDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
           P+++     +++            ++ +D   P  E+       ++  L
Sbjct: 148 PEYEEKEFLQRVRSMYLRMVEMGLLIYIDASKPLSEVYGRIWDIVYGRL 196


>UniRef50_Q22U70 Thymidylate kinase family protein n=1 Tax=Tetrahymena thermophila
           SB210 RepID=Q22U70_TETTH
          Length = 211

 Score =  138 bits (346), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 33/228 (14%), Positives = 67/228 (29%), Gaps = 41/228 (17%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           S     I   G D  GK++   +LVN L                 +  +  +   IG   
Sbjct: 2   SKRGLFIVFEGLDRCGKTSQCENLVNFLKESG---------KKAIMKRYPDRTTTIGQTI 52

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVE 130
             YL+ K                  +  + S  R  +  ++     +G  ++ DRY    
Sbjct: 53  NNYLQGKQ-----------NLSDQAIHLIFSANRWEQQEEIKKILDEGTNIVCDRYCYS- 100

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---- 186
                        T+     I+  +  +  L        P +++ L   ++    R    
Sbjct: 101 ---------GAVYTSAKGYDIEWCKNPDKGL------IKPDIVLYLHAPKEVISKRSGFG 145

Query: 187 KPDHQLAALQEKIAV-TPQLTFNGAKILELDGRHPADEILQASLRAIH 233
              ++    Q+K+      L      ++ +D     +E+     + I 
Sbjct: 146 GEVYEKEEFQQKVREAFDNLLQKEDNVVFIDASGTKEEVFDLINQNIK 193


>UniRef50_Q22018 Probable thymidylate kinase n=3 Tax=Caenorhabditis RepID=KTHY_CAEEL
          Length = 218

 Score =  137 bits (345), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 36/227 (15%), Positives = 71/227 (31%), Gaps = 31/227 (13%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
            +     +I   G D SGKST    LV  +  +        G +S      +   P   +
Sbjct: 3   TDQKRGLLIVFEGLDRSGKSTQAKRLVESINKKSTES----GDASSSPSAVLQAFPDRSS 58

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQ 128
             G+ +        +            +  L S  R  K + +     +G  +I DRY  
Sbjct: 59  SIGKLIDQYLRKEIDMDEHA-------LHLLFSADRFSKNQMIRDNIAKGIDVICDRYCY 111

Query: 129 VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-- 186
                       +A +       + +R  ++ L        P  ++   +  + A  R  
Sbjct: 112 S----------GVAYSLAKGLPEQWVRSSDVGL------PKPDAVLFFDVSPEVAAQRGG 155

Query: 187 --KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRA 231
             +   + A +Q+K+A       + A    ++     D + +   R 
Sbjct: 156 FGEERLETATIQQKVAAVMPTLRDDAYWKTVNADGDLDSVEKNVFRI 202


>UniRef50_D1S998 Thymidylate kinase n=1 Tax=Micromonospora aurantiaca ATCC 27029
           RepID=D1S998_9ACTO
          Length = 718

 Score =  137 bits (345), Expect = 3e-31,   Method: Composition-based stats.
 Identities = 42/238 (17%), Positives = 75/238 (31%), Gaps = 42/238 (17%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
           +    +   G +G+GKST  A L   L A+     +     +  +GE I  L +   P  
Sbjct: 476 SSGLFVVFEGGEGAGKSTQLAELAERLRAQGRDVVVTREPGATPVGERIRSLVLGTTP-- 533

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVE 130
                                      L +  RA+     +     +G ++I+DRY    
Sbjct: 534 ----------------GEAPSPRAEALLYAADRAHHVATVVRPALVRGAVVISDRYVDSS 577

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH 190
           +    + G            +  L               P L++ L ++ +T  +R  D 
Sbjct: 578 LA---YQGAGRTLPVDE---VSWLSS------WATGGLKPDLVVLLDVEPRTGLSRVEDR 625

Query: 191 -------QLAAL----QEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
                  +  +L    + + A       +  + L LD   P DE   A  R +   L+
Sbjct: 626 AEGTDRLEAESLTFHERVRYAFLDLAAGDPKRYLVLDASRPIDETADAVARRVGELLA 683


>UniRef50_A4RZW8 Predicted protein n=13 Tax=Eukaryota RepID=A4RZW8_OSTLU
          Length = 218

 Score =  137 bits (344), Expect = 3e-31,   Method: Composition-based stats.
 Identities = 42/225 (18%), Positives = 68/225 (30%), Gaps = 38/225 (16%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           +     +   G D  GKST    LV+ L AR              +  +  +   +G   
Sbjct: 8   AARGAFVLFEGADRCGKSTQAMRLVHTLEARGVE---------AELWRYPDRATAMGKMI 58

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVE 130
            +YLRSK+                 +  L +  R  K   M  K   G  L+ DRY    
Sbjct: 59  DQYLRSKSEMEDGA-----------IHLLFAANRWEKKALMERKLASGVTLVCDRYSYSG 107

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---- 186
                  G            ++  R  E+ L        P  L+ L +  + A  R    
Sbjct: 108 CAFTAAKGVD-------GLDLEWCRAPEVGL------PRPDALMYLELSLEDAAKRGGFG 154

Query: 187 KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRA 231
           +  ++   +Q  +  + +          +D     D I    LR 
Sbjct: 155 EERYETTEMQRAVKASFEAMRED-WWDVIDANREPDVIQDEVLRI 198


>UniRef50_B6K7E8 Thymidylate kinase n=1 Tax=Schizosaccharomyces japonicus yFS275
           RepID=B6K7E8_SCHJY
          Length = 209

 Score =  137 bits (344), Expect = 3e-31,   Method: Composition-based stats.
 Identities = 39/230 (16%), Positives = 63/230 (27%), Gaps = 48/230 (20%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + +   G D SGKST    L   L  R                  + + P  G   G+ 
Sbjct: 3   GKFVVFEGLDRSGKSTQAELLKKALIDRGQRA-------------ILLRFPDRGTTIGKQ 49

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           + +   + ++ P          +  L S  R      +      G   I DRY    V  
Sbjct: 50  IDAYLKNKNKLPDEA-------IHLLFSANRWELASTIEAALADGVHCIVDRYSFSGVAF 102

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----KPD 189
                                +Q E  L        P +++   +D   A  R       
Sbjct: 103 SA----------AKGMDWDWCKQPERGL------PSPDIVLFFQVDPNIASKRAGFGNER 146

Query: 190 HQLAALQEKIAVTPQLTF--------NGAKILELDGRHPADEILQASLRA 231
           ++L   Q  +A    L          N    L +DG    +++    L  
Sbjct: 147 YELPVFQRTVAEKYALLRQEFVKERKNDDSWLMIDGNQSIEQVHLKILTI 196


>UniRef50_A6NRP2 Putative uncharacterized protein n=2 Tax=Bacteria
           RepID=A6NRP2_9BACE
          Length = 224

 Score =  136 bits (343), Expect = 4e-31,   Method: Composition-based stats.
 Identities = 42/240 (17%), Positives = 73/240 (30%), Gaps = 41/240 (17%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
             ++I   G DGSGKST  A L   L          +          + ++ + G     
Sbjct: 2   SGKLIVFEGTDGSGKSTQFAKLCERLEQEGTDFRRLIFPQYKEPSSALLRMYLNG----- 56

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEV 131
                     E  + P            +  R   ++K      Q G L+++DRY     
Sbjct: 57  ----------EFGTHPDDVNPYAASTFYAVDRYAAWKKDWGSYYQNGGLVLSDRYTTSNA 106

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF----ARK 187
                   +L +    N +I+ L   E      +    P L+I L +    A     AR+
Sbjct: 107 ---VHQTCKLPEAEWEN-FIRWLFDFECG---KLGLPAPDLVIYLDMPTDKAVEMLRARE 159

Query: 188 P-----------DHQLAALQEKIAVTPQLTFNGAKILELDGR---HPADEILQASLRAIH 233
                       D +  A   + A+         ++  +DG       ++I +     I 
Sbjct: 160 KATHTKGDIHEVDTEYLAKCRRTALAAAGLLGWRRVSCVDGTGAVRSIEDIHREIWDIIT 219


>UniRef50_A1VCE6 Thymidylate kinase n=15 Tax=Bacteria RepID=KTHY_DESVV
          Length = 224

 Score =  136 bits (343), Expect = 5e-31,   Method: Composition-based stats.
 Identities = 43/239 (17%), Positives = 76/239 (31%), Gaps = 49/239 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G +GSGKST    L   L                  G  +++ P  G+  GR LR
Sbjct: 2   FITFEGIEGSGKSTALQGLAAWLQQHGH-------------GVAVTREPG-GSRLGRTLR 47

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
           S    +               ++L    RA    + +     +G ++++DRY    V   
Sbjct: 48  SILLDLGNTD-----ITPEAELFLYLADRAQHVAQVVRPALDEGMVVLSDRYADSTVVYQ 102

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-------- 186
            +         G      MLRQ        +    P L I L ++ +    R        
Sbjct: 103 GY---------GRGLDPMMLRQFNDVA---VGGLWPDLTILLDLEPEAGLNRALARNIRE 150

Query: 187 -----KPDHQLAALQEKIAVTPQL----TFNGAKILELDGRHPADEILQASLRAIHAAL 236
                +   +  +L     V          +G +   +D     +++++  +  + AAL
Sbjct: 151 GMHAAEGRFEAESLAFHTRVREGYLTWAALHGGRYRVVDATQSPEDVVRDVVGIVAAAL 209


>UniRef50_B8BUD4 Predicted protein n=1 Tax=Thalassiosira pseudonana
           RepID=B8BUD4_THAPS
          Length = 276

 Score =  135 bits (340), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 35/243 (14%), Positives = 71/243 (29%), Gaps = 34/243 (13%)

Query: 5   NMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLP 64
           N +         I + G D  GK+T  + LV  L +       Y          +  +  
Sbjct: 27  NPTTTQPKRGAFILLEGVDRCGKTTQVSLLVKHLLSLSLATVAY---------RFPDRST 77

Query: 65  VIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITD 124
            +G+    YL S                   +  L S  R      +      G  ++ D
Sbjct: 78  QVGSLINSYLTSSTP--------TAPLDDRAIHLLFSANRWEASTSLARTLASGTNIVCD 129

Query: 125 RYPQVEVPGFRFDGPQ-LAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTA 183
           RY    V        +     +GG   ++     ++ L        P  +I L +++  A
Sbjct: 130 RYAYSGVAFTSAKVEEDRGSMSGGELGLEWCIAPDVGL------PAPDCVIFLDLEQDEA 183

Query: 184 FARK--PDHQLA------ALQEKIAVTPQLTFNGAK--ILELDGRHPADEILQASLRAIH 233
             R      +         ++++ A    L     +     +D     +E+    +  ++
Sbjct: 184 EKRGGYGGERYEKRDLQMRVRKRFAELQSLDEQNGRVPWHVVDASQSIEEVTGELVSIVN 243

Query: 234 AAL 236
             +
Sbjct: 244 DTI 246


>UniRef50_UPI0001C375B1 putative thymidylate kinase n=1 Tax=Ruminococcus flavefaciens FD-1
           RepID=UPI0001C375B1
          Length = 224

 Score =  135 bits (340), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 37/241 (15%), Positives = 73/241 (30%), Gaps = 40/241 (16%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            ++I I G DGSGK+T TA L  +L         +           + ++ + G      
Sbjct: 3   GKLIVIEGLDGSGKATQTALLCEKLKTLGVEFDHFSFPDYNSESSLLVRMYLDGKF---- 58

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQVEVP 132
                                      +C R   FR +   K + G +++ DRY      
Sbjct: 59  -----------GDNAAEVNPYAASCFFACDRYASFRTQWQDKYEGGHIIVCDRYTTSNA- 106

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTA--------- 183
                  +L      + ++  L   E   Y+ +    P  +I L +D +           
Sbjct: 107 --VHQCSKLPDG-EWDDFVNWLFDFE---YRKIGLPEPDAVIYLRVDPEIGQELLKKRYN 160

Query: 184 --FARKPDHQLAALQEKIAVT------PQLTFNGAKILELDGRHPADEILQASLRAIHAA 235
               +K  H+        +            ++  + +  +G     EI +    A+ + 
Sbjct: 161 GDEKKKDIHEKDEDHLNRSRLTADHCAKLYGWHTIECVNENGMRDKQEIAEEVFEAVRSV 220

Query: 236 L 236
           +
Sbjct: 221 I 221


>UniRef50_Q8SZQ0 RE69454p (Fragment) n=18 Tax=Drosophila RepID=Q8SZQ0_DROME
          Length = 225

 Score =  135 bits (339), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 40/240 (16%), Positives = 69/240 (28%), Gaps = 44/240 (18%)

Query: 5   NMSIINSTPVR--VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQ 62
           N+ I+ S   R  +I   GCD SGK+T +  LV  L ++                 +  +
Sbjct: 10  NIKIVMSAGKRGALIIFEGCDRSGKTTQSRLLVELLKSKGI---------PTLPMNFPER 60

Query: 63  LPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLI 122
              IG     YL           +        ++  + S  R     ++  K  +G  L+
Sbjct: 61  SSSIGQVINSYL-----------TNSKDLPDEVIHLMFSANRWEHINQVKEKLLEGTTLV 109

Query: 123 TDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQT 182
            DRY              +A +             E  L        P  +  L      
Sbjct: 110 VDRYSFS----------GVAYSAAKGLDFDWCYAPERGL------IKPDAVFYLRAPPND 153

Query: 183 AFAR----KPDHQLAALQEKIAVTPQLT--FNGAKILELDGRHPADEILQASLRAIHAAL 236
              R    K  ++    Q ++A          G+   + D R   +++           L
Sbjct: 154 LTHRGQYGKERYEKVEFQGRVAEVFNRICSKEGSYFHQFDARQSVEDLHAQIASITEELL 213


>UniRef50_Q45RR2 Deoxythymidylate kinase n=1 Tax=Cyprinid herpesvirus 3
           RepID=Q45RR2_9VIRU
          Length = 233

 Score =  134 bits (336), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 38/231 (16%), Positives = 73/231 (31%), Gaps = 41/231 (17%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           +    +I + G D SGKST    LV  L                 +  +  +   IG   
Sbjct: 18  TRRGALIILEGVDRSGKSTQCRMLVKALLEMGVE---------AELMRFPDRTTPIGQMI 68

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVE 130
             YL +K+                +V  L S  R      +  K  +G  ++ DRY    
Sbjct: 69  NSYLLNKS-----------DLDDHVVHLLFSANRWEAASDLKRKLMKGTTIVLDRYAFSG 117

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK--- 187
           V                   ++  ++ ++ L        P L++ L I+     +R    
Sbjct: 118 VAFTA---------AKPGFELEWCKRTDVGL------PKPDLVVFLAIEASAVESRGGFG 162

Query: 188 -PDHQLAALQEKIAVTPQLTFNG--AKILELDGRHPADEILQASLRAIHAA 235
              ++++A Q  +    ++          ++D     +++    LR    A
Sbjct: 163 DERYEVSAFQAAVRENFEVLMKDVTVNWRKVDAARTPEQVHGDILRLTDDA 213


>UniRef50_D2RGJ1 Thymidylate kinase n=2 Tax=Archaeoglobaceae RepID=D2RGJ1_ARCPR
          Length = 199

 Score =  133 bits (335), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 45/228 (19%), Positives = 72/228 (31%), Gaps = 47/228 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA+ G DGSGK+T+   LV EL  R      +   +    G+ I Q+            
Sbjct: 2   LIAVEGIDGSGKTTIVRFLVEELKKRGYDVVAFKEPTDSEYGKKIRQILKERK------- 54

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQVEVPGF 134
                                + L    R +  R  +L   + G ++I DRY    +   
Sbjct: 55  ---------------ISPEEELKLFIKDREFNVRNNILPALKSGKVVIMDRYYYSTIAYQ 99

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF-----ARKPD 189
              G  + K    N                     P L+I L +  +TA       RKPD
Sbjct: 100 GALGLDIGKIKTLNE----------------QFPKPDLVIILDVSPETALKRIKAKRKPD 143

Query: 190 HQLA-ALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                    K+            I+ +D     +E+ +  L+ +   L
Sbjct: 144 RFEDLEYLRKVRNIFLSL--KNNIVVIDAERDIEEVKRDVLKVVLEHL 189


>UniRef50_A3DM71 Probable thymidylate kinase n=1 Tax=Staphylothermus marinus F1
           RepID=KTHY_STAMF
          Length = 199

 Score =  133 bits (334), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 31/236 (13%), Positives = 70/236 (29%), Gaps = 47/236 (19%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           ++      + + G DG+GK+++   L + L  +    H      +    E +        
Sbjct: 1   MSENNGFFLVLEGIDGAGKTSIAFKLRDFLVEKGFNVHYTYEPYNTLYVEAL-------- 52

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYP 127
                          K          L     +  R    R ++L   ++G+++I DRY 
Sbjct: 53  ---------------KKKYNEYRDAYLDALTYAADRLVHIRTEILPYLRRGYIVICDRYY 97

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK 187
                     G  +      N +                +  P L I L +D      R+
Sbjct: 98  YSSAAYQSAQGAPIEWVLEINKY----------------ALKPDLTIYLDVDPAIGVKRR 141

Query: 188 -------PDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                  P+++      ++        +   ++ +D     D++ +   + +   L
Sbjct: 142 KGLNTRFPEYEKLDFLYRVRENYLWLVDKGYMVLVDANREFDKVYRDVEKIVLEHL 197


>UniRef50_Q8SS22 THYMIDYLATE KINASE n=1 Tax=Encephalitozoon cuniculi
           RepID=Q8SS22_ENCCU
          Length = 191

 Score =  133 bits (333), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 41/226 (18%), Positives = 70/226 (30%), Gaps = 43/226 (19%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
           +  + +   G D SGK+T+  SL   L   +PT  I     SG +G+ I           
Sbjct: 2   SKGKFVVFEGLDRSGKTTIVGSLYESLLPIVPTSKIRFPNRSGPVGKIIDGYLQKKTNLE 61

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEV 131
                                   +  L S  R    R M+ + ++  +++ DRY     
Sbjct: 62  S---------------------ETIHLLFSADRYEH-RLMIEELRRDTIILCDRYSMS-- 97

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK---- 187
                    +A +      +      E  L        P L I + +       RK    
Sbjct: 98  --------GIAYSVAKGLSLDWCIASEALL------PKPDLTIFIDVPMDEICRRKGFGT 143

Query: 188 PDHQLAALQEKIAVTPQLTFNGAK-ILELDGRHPADEILQASLRAI 232
             H      +K+    Q      +  L +DG  P  E+++   + I
Sbjct: 144 EIHDTVPFLKKVLSAYQALLKKEENTLVVDGTLPVREVVEIVRKRI 189


>UniRef50_C9SNG5 Thymidylate kinase n=7 Tax=Sordariomycetes RepID=C9SNG5_VERA1
          Length = 285

 Score =  133 bits (333), Expect = 7e-30,   Method: Composition-based stats.
 Identities = 33/252 (13%), Positives = 70/252 (27%), Gaps = 60/252 (23%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
           T   ++ + G D SGK+T    L            +           +  +   IG    
Sbjct: 51  TRGALVILEGLDRSGKTTQVKLLEQRFVELGKKVKV---------MRFPDRSTPIGQMID 101

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEV 131
            YL+S                  ++  L S  R    + +      G  ++ DRY    +
Sbjct: 102 AYLKSSVE-----------MDDHVIHLLFSANRWEAVKTIRQLLASGTTVLCDRYYHSGI 150

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----K 187
                           +  +   R  ++ L        P L++ L +DE TA +R     
Sbjct: 151 VYSA-------AKHNPSLSLHWARAPDVGL------PRPDLVLFLDLDEATAKSRGGWGG 197

Query: 188 PDHQLAALQEKIAVT-----------------------PQLTFNGAKILELDGRHPADEI 224
             ++   +Q ++                           +       ++ +D     +E+
Sbjct: 198 ELYERGEMQRRVRELFWGLAMGRIGADGGLGDEDRRVDREFRQEEEDLVVVDAGASVEEV 257

Query: 225 LQASLRAIHAAL 236
            +     +   +
Sbjct: 258 AEGIWEKVQPRV 269


>UniRef50_D0MVS5 Thymidylate kinase n=1 Tax=Phytophthora infestans T30-4
           RepID=D0MVS5_PHYIN
          Length = 216

 Score =  132 bits (332), Expect = 8e-30,   Method: Composition-based stats.
 Identities = 35/232 (15%), Positives = 65/232 (28%), Gaps = 39/232 (16%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           +     +   G D  GK+T T  L + L A   +           +  +  +   IG   
Sbjct: 2   TRRGIFLLFEGVDRCGKTTQTKLLHDALNASSSS-------QPSALLHFPDRSTAIGKSI 54

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVE 130
             YL           ++       ++  L S  R     K+      G  +I DRY    
Sbjct: 55  HSYL-----------TSSEAMDDHVIHLLFSANRWEAASKIESILASGQHIIMDRYSFSG 103

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---- 186
           V                   +      E+ L        P  +I L +    A  R    
Sbjct: 104 VAFSAAKS---------GMSLDWCWAPEIGL------PKPDAIIFLDVPVTQASTRADFG 148

Query: 187 KPDHQLAALQEKI-AVTPQLTFNGAK-ILELDGRHPADEILQASLRAIHAAL 236
           +  ++  A QEK+      +          +D     +++ +  +      +
Sbjct: 149 QERYETTAFQEKVYRNFYDIMERATPKWHVVDATGTIEQVQEKVMAIAKETI 200


>UniRef50_P23919 Thymidylate kinase n=22 Tax=Euteleostomi RepID=KTHY_HUMAN
          Length = 212

 Score =  132 bits (332), Expect = 9e-30,   Method: Composition-based stats.
 Identities = 43/234 (18%), Positives = 74/234 (31%), Gaps = 41/234 (17%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           + +    +I + G D +GKST +  LV  L A               +  +  +   IG 
Sbjct: 1   MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGH---------RAELLRFPERSTEIGK 51

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQ 128
               YL+ K+                 V  L S  R  +   +  K  QG  L+ DRY  
Sbjct: 52  LLSSYLQKKS-----------DVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAF 100

Query: 129 VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK- 187
             V                N  +   +Q ++ L        P L++ L +    A  R  
Sbjct: 101 SGVAFT---------GAKENFSLDWCKQPDVGL------PKPDLVLFLQLQLADAAKRGA 145

Query: 188 ---PDHQLAALQEK-IAVTPQLTFNGA-KILELDGRHPADEILQASLRAIHAAL 236
                ++  A QE+ +    QL  +       +D     + + +        A+
Sbjct: 146 FGHERYENGAFQERALRCFHQLMKDTTLNWKMVDASKSIEAVHEDIRVLSEDAI 199


>UniRef50_D1YVU8 Probable thymidylate kinase n=2 Tax=Euryarchaeota
           RepID=D1YVU8_METPS
          Length = 201

 Score =  131 bits (330), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 37/233 (15%), Positives = 71/233 (30%), Gaps = 43/233 (18%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           +   R+I I G DG+GK+T    L   L             + G+ G+ I++    G+  
Sbjct: 2   TRKGRLITIEGIDGTGKTTQVQLLKEWLERHGVEAVALKEPTQGKYGQEIARRAHAGSF- 60

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVE 130
                                    +   +   R    + +    + G  +I DRY    
Sbjct: 61  --------------------GPRDELRLFMEDRREDVEKNIRPALESGKSVIMDRYYLSN 100

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH 190
           +      G               L    ++L     S +P L+I L +  + + AR    
Sbjct: 101 MAYQGARG---------------LDPERIRLENEAFSPVPDLIIILDLAPEKSMARVNTR 145

Query: 191 -------QLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                  +  A  EK+             + ++   P  ++ +  + A+   L
Sbjct: 146 KNVVGHFENEAYLEKVRKIFLAIGKQPNAVVINTEAPVADVHERIVDAVRDRL 198


>UniRef50_A9A2S6 Thymidylate kinase n=1 Tax=Nitrosopumilus maritimus SCM1
           RepID=A9A2S6_NITMS
          Length = 193

 Score =  131 bits (330), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 37/220 (16%), Positives = 69/220 (31%), Gaps = 41/220 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I I G D +GK T +  L   L  R     ++               P      G+ +R
Sbjct: 2   IIVIEGGDQAGKLTQSTMLEKALKKRKIKTKLF-------------HFPDYKTHIGKEIR 48

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                  + P         ++  LLS  R  K  ++    ++  +LI +RY         
Sbjct: 49  QYLDGKRKFP-------PQVIHCLLSANRWEKLEQIKTAQEKNSVLIMNRYYHSN----- 96

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD-----H 190
                L          K L   +  L          L+I L + ++ +F R+        
Sbjct: 97  -----LVYGLANGMKEKWLESLDAGL------PKADLVILLDVTQKESFNRQKTNRDKFE 145

Query: 191 QLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLR 230
           +      KI+   + T    +   +D      E+ +  ++
Sbjct: 146 KNEEFLRKISRIYKTTAKKKRWKIIDATKSKQEVHEEIMK 185


>UniRef50_Q46DH6 Probable thymidylate kinase n=4 Tax=Methanosarcinaceae
           RepID=KTHY_METBF
          Length = 205

 Score =  131 bits (328), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 38/233 (16%), Positives = 80/233 (34%), Gaps = 41/233 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            ++I + G DGSGKST+   L      + P    +    +       ++  + G    + 
Sbjct: 3   GKLITLEGIDGSGKSTVAEKL-----QKNPEIKAFKPVFT----REPTRGTLTGDAVEKA 53

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVP 132
           ++S      E             ++L +   A    K +    + G ++I+DRY      
Sbjct: 54  IQSDTDQFAE-------------LFLFTADHAEHLAKLIKPALENGKIVISDRYSDSR-- 98

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR------ 186
            + + G  L         ++ ++           + +P L     I  + +  R      
Sbjct: 99  -YAYQGITLKTRLEN--PLEWVKDLHRS-----WTIVPDLTFLFDIRPEISIERCGKRGE 150

Query: 187 -KPDHQLAALQEKIAVTPQLTFNG-AKILELDGRHPADEILQASLRAIHAALS 237
                +L  LQ   A+  +L  +   + + +D     + I +  ++ I   LS
Sbjct: 151 QSKFEKLEFLQGVRAIFLKLAADDPERFVVIDASRSPEYIEKEVVKKILEFLS 203


>UniRef50_C7PHF5 Thymidylate kinase n=1 Tax=Chitinophaga pinensis DSM 2588
           RepID=C7PHF5_CHIPD
          Length = 228

 Score =  131 bits (328), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 43/243 (17%), Positives = 70/243 (28%), Gaps = 45/243 (18%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           R IAI G DG+GKST    L      +                  I Q  V G    ++L
Sbjct: 6   RFIAIEGLDGAGKSTQINLLQQFFNQQGIETRFVHFP--------IVQEGVFGEMIAKFL 57

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           R +   V +           LV  L +  R      +      G++++ DRY    +   
Sbjct: 58  RGEFGDVKD-------VHPQLVALLFAEDRKAFSHTINEWLASGYVVLVDRYVLSNIA-- 108

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGID---EQTAFARKPDHQ 191
            F   +L            +   E   Y++     P L + L +     + A AR+   +
Sbjct: 109 -FQCAKLKTDKEKQELRDWINMFE---YEYNRIPQPDLSVYLDVPFSHTEQALARRRSGE 164

Query: 192 LAALQEKIAVTPQLTF--------NGAKILELDGR-------------HPADEILQASLR 230
                       +  F            + + D                  +EI  A + 
Sbjct: 165 DRKYLNGKDDIHEKDFSLQLAVKREYEILADTDATVTKIVCYDQDNKMRSVEEIHAAIIH 224

Query: 231 AIH 233
            I 
Sbjct: 225 NIT 227


>UniRef50_O30175 Probable thymidylate kinase n=1 Tax=Archaeoglobus fulgidus
           RepID=KTHY_ARCFU
          Length = 196

 Score =  130 bits (327), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 39/228 (17%), Positives = 72/228 (31%), Gaps = 45/228 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA+ G DG+GK+T+ A +   L  +     +       + G+ I               
Sbjct: 2   LIAVEGIDGAGKTTIAAYIAELLKEKGYKVKVLKEPGDSKFGKKIK-------------- 47

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
                     S+         + L    R    R+ +L   Q G+ ++ DRY    +   
Sbjct: 48  ----------SSEERLSPEEELELFLKDREIDARENILPALQSGYAVVMDRYYFSNIAYQ 97

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
              G         N  I               +  P L I L ++ + A  R       +
Sbjct: 98  SARGIDARLIREMNEKI---------------APKPDLTILLDVEPEIALERVRKRGKLS 142

Query: 195 LQEKIAVTPQ-----LTFNGAKILELDGRHPADEILQASLRAIHAALS 237
             EK+    +     L       + +D   P +E+ +   + I + L+
Sbjct: 143 PFEKLDYLRKVRKCFLENADETTVVVDASKPLEEVKEEVRKVIESFLN 190


>UniRef50_Q5ZVP1 Thymidylate kinase n=5 Tax=Legionella RepID=KTHY_LEGPH
          Length = 212

 Score =  130 bits (327), Expect = 4e-29,   Method: Composition-based stats.
 Identities = 39/237 (16%), Positives = 79/237 (33%), Gaps = 38/237 (16%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           ++S   ++I I G +G+GKST    +V  L+ +             +I    ++ P  G 
Sbjct: 1   MSSLTGKLIVIEGLEGAGKSTAVNLVVELLSQK-------------KISTITTREPG-GT 46

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQ 128
             G  LRS   +          +    ++ L +       + +      G  +I DR+  
Sbjct: 47  KIGEILRSIIKNPEYNNVLDDRSE---LLLLYAARIQLIEQVIKPALNVGQWVIADRFEL 103

Query: 129 VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-- 186
             +              GG   + M    EL  +  +  + P L + L I+ +    R  
Sbjct: 104 STLAYQ-----------GGGRKMDMRVINELSNF-CLKGFKPDLTLYLDINPELGMIRAK 151

Query: 187 ------KPDHQLAALQEKIAVTPQLTFNGAK-ILELDGRHPADEILQASLRAIHAAL 236
                 + + +      +I  T  +       I+ +D     +E+  +    I   +
Sbjct: 152 SRGKFDRIEQESIEFFHRIHDTYHILVKQNPEIIMIDANRSLEEVQSSIQSVIEEFI 208


>UniRef50_A0CKK9 Chromosome undetermined scaffold_2, whole genome shotgun sequence
           n=2 Tax=Paramecium tetraurelia RepID=A0CKK9_PARTE
          Length = 216

 Score =  130 bits (326), Expect = 4e-29,   Method: Composition-based stats.
 Identities = 43/230 (18%), Positives = 71/230 (30%), Gaps = 45/230 (19%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
                IA+ G D SGKST    L  +L A+                 +  +   +G    
Sbjct: 13  NRGVFIALEGLDKSGKSTQAKLLSQKLNAKKV--------------SFPDRTTQLGLIIS 58

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEV 131
            YLR       E           ++  L S  R  +   +L + Q G  +++DRY    V
Sbjct: 59  DYLRGNKNMSDE-----------VIHLLFSANRWEQHTSILKQLQDGTNIVSDRYAYSGV 107

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----K 187
                              I+  +  +  L Q      P +   L    +    R    K
Sbjct: 108 AFSA----------AKGLPIEWCKAPDAGLIQ------PDMTFYLTAPIEELSKRGDYGK 151

Query: 188 PDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
             ++ ++ Q+K+              ++D     DEI    L  I   L+
Sbjct: 152 EIYENSSFQQKVGSFFDQLALEENFYKIDALKSIDEIQAEILNRISEKLN 201


>UniRef50_B9KXL4 Thymidylate kinase n=11 Tax=Bacteria RepID=KTHY_THERP
          Length = 210

 Score =  130 bits (326), Expect = 4e-29,   Method: Composition-based stats.
 Identities = 34/233 (14%), Positives = 66/233 (28%), Gaps = 45/233 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G +G+GK+T  A L   L     +  +        +GE I +  + G        
Sbjct: 4   FITFEGPEGAGKTTQCALLAARLREAGYSLLVTREPGGTPLGETIREWLLAG-------- 55

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQVEVPGF 134
                                  L +  RA     ++    ++G +++ DRY    +   
Sbjct: 56  -------------EALRPETEALLFTAARAEHVWDRIRPALERGTIVLCDRYVDSTLA-- 100

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-------- 186
            + G               LR+             P L I L +  +   AR        
Sbjct: 101 -YQGAG------RGLDEGWLRELHRIA---TGDLWPDLTILLDVPVEVGLARRRAAAATI 150

Query: 187 -KPDHQLAALQEKIAVTPQLT--FNGAKILELDGRHPADEILQASLRAIHAAL 236
            + D +  A   ++          +  +   +D   P + +  A    +   +
Sbjct: 151 TRLDQEELAFHRRVRAWYHAAAQRDPQRWRVVDATLPPEVVADAVWATVTEVM 203


>UniRef50_Q601T1 Thymidylate kinase n=6 Tax=Mycoplasma RepID=KTHY_MYCH2
          Length = 211

 Score =  130 bits (326), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 43/226 (19%), Positives = 72/226 (31%), Gaps = 38/226 (16%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I+  G D SGKST+       L  + P + I      G            G      L+
Sbjct: 2   FISFEGIDASGKSTVMDLFAKYLKIKFPEKEIVTTFEPG------------GKNLKEALQ 49

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
            +   + +     P       +   +  R +  R +    + G +++ DRY    +    
Sbjct: 50  IREFLLSKNNQISPYVEM---LLFATARRIHLERLIWPALKAGKIVLCDRYIDSSIAYQG 106

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK---PDHQL 192
           F         G    I ++      + +      P L I L I    AF R     DH  
Sbjct: 107 F---------GNGLDIDLVTSLNSLISENTF---PDLTIFLDIKISKAFERMGIFRDHNR 154

Query: 193 AALQEKIAVTPQLTFNGAKIL--------ELDGRHPADEILQASLR 230
             L+ +     +   NG + L        ++DG    DE+L   + 
Sbjct: 155 DRLENRGVEFYEKVINGYEFLAKKNKNFFKIDGNGTYDEVLDLIID 200


>UniRef50_A5DSK9 Thymidylate kinase n=8 Tax=Saccharomycetales RepID=A5DSK9_LODEL
          Length = 237

 Score =  129 bits (325), Expect = 6e-29,   Method: Composition-based stats.
 Identities = 44/234 (18%), Positives = 77/234 (32%), Gaps = 25/234 (10%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            ++I I G D SGKST  + LV++L              S ++ ++  +   IG     Y
Sbjct: 4   GQLILIEGLDRSGKSTQASLLVSKL---GHASSSSSPPCSSKLLKFPDRTTPIGKLINEY 60

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           L +K   + ++ +            L    R    +++     QG  ++ DRY    +  
Sbjct: 61  LTNKEFQLDDQAA----------HLLFLANRWELNQEIHNLLNQGCFVVLDRYIYSGIAY 110

Query: 134 F----RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK-- 187
                  D  +   +         L   +  L        P L + L +D +    RK  
Sbjct: 111 TLAKNNLDDSEANTSISRGKKSSNLASVDWLLGPDKGLPKPDLTMFLTLDLEEISKRKGW 170

Query: 188 --PDHQLAALQEKIAVTPQLTFN---GAKILELD-GRHPADEILQASLRAIHAA 235
               ++L   Q K+        N      I  LD G    +E+       I + 
Sbjct: 171 GNERYELQQFQAKVKRCFLQILNSNQDKSIEILDVGEKSIEEVTNQLWDVIVSH 224


>UniRef50_D1BLN7 Thymidylate kinase n=15 Tax=Bacteria RepID=D1BLN7_VEIPT
          Length = 228

 Score =  129 bits (324), Expect = 7e-29,   Method: Composition-based stats.
 Identities = 32/247 (12%), Positives = 61/247 (24%), Gaps = 45/247 (18%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
             +I + G DGSGK+T T  LV  L             +         ++ + G      
Sbjct: 2   GTLIILEGGDGSGKATQTKLLVERLTKEGHAVKSVSFPNYDSGAAMPIKMYLAG------ 55

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVP 132
                    E           +   + +  R   FR       + G ++I DRY      
Sbjct: 56  ---------EFGKDVHDVNPYVASSMYAIDRFASFRTDWEQFYKNGGIIIADRYTTSN-- 104

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD--- 189
                  +   +     ++  L   E   +Q      P  +  L +  + + A   +   
Sbjct: 105 -MVHQMVKYDDSKERTAFLDWLEDFE---FQKFGLPKPDAVCLLDMPLEVSEALMAERTG 160

Query: 190 ----------HQLAALQEKIAVTPQLTFNGAKILEL---DGR-------HPADEILQASL 229
                              +    +      +   +   D            +EI     
Sbjct: 161 KTGGNTGDIHEGNHTYLVAVHDAYEELVKRYQWHRIPCVDKAKSSQYTLRTIEEIHNDVY 220

Query: 230 RAIHAAL 236
             +   L
Sbjct: 221 SVVENLL 227


>UniRef50_Q0A8S2 Thymidylate kinase n=16 Tax=Gammaproteobacteria RepID=KTHY_ALHEH
          Length = 217

 Score =  129 bits (324), Expect = 8e-29,   Method: Composition-based stats.
 Identities = 38/237 (16%), Positives = 80/237 (33%), Gaps = 41/237 (17%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
           T  R I + G +G+GKST    +   L  +              I   +++ P  G P G
Sbjct: 2   TRGRFITLEGLEGAGKSTALTRVREYLQRQG-------------IDAVMTREPG-GTPLG 47

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEV 131
             +R+         S PP       + + +    +  +++    ++G  ++ DR+     
Sbjct: 48  ERIRALLLG----QSEPPMAPATEALLMFAARSEHLDKRIWPALERGQWVVCDRFTD--- 100

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP--- 188
             + + G            ++   Q          +  P L + L +  +T  AR     
Sbjct: 101 ASYAYQGWGRGLGAERIAALEDWTQ---------GALRPDLTLWLDVPVETGLARAAGRG 151

Query: 189 ------DHQLAALQEKIAVTPQLTFNG--AKILELDGRHPADEILQASLRAIHAALS 237
                 + +     E++             +I  +D   P + +L A   A+ +A++
Sbjct: 152 EAPDRFEQERDGFFERVHEGYAALAERFPERIRRVDAGQPLEAVLTALEEALASAVT 208


>UniRef50_A1RTS9 Thymidylate kinase n=3 Tax=Thermoproteaceae RepID=A1RTS9_PYRIL
          Length = 205

 Score =  129 bits (324), Expect = 8e-29,   Method: Composition-based stats.
 Identities = 41/229 (17%), Positives = 79/229 (34%), Gaps = 48/229 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            +AI G DGSGKST+   L   L    P  ++    S G IG  I +  + G     ++ 
Sbjct: 3   FVAIEGIDGSGKSTVILQLAEML----PKVYVTREPSGGPIGRLIKEWALKGGTIDPHVD 58

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEVPGF 134
           +                      L +  R   + R++  K ++G+++I++RY +  +   
Sbjct: 59  A---------------------LLFAADRIEHYKREIEPKVREGYIVISERYIESSIA-- 95

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH---- 190
            + G            I  ++          A     + I L +D + A AR        
Sbjct: 96  -YQGAA-------GVPIDFIKIINS------AVPKADITIILDVDPEIAIARIKQRGDSE 141

Query: 191 --QLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
             + +A  +++               +D   P + + +     I   L+
Sbjct: 142 KYEHSAFLKRVREIYLQRAREEGYPVVDASRPPNVVAKDVAEIITQMLN 190


>UniRef50_D0YPY2 Thymidylate kinase n=3 Tax=Mobiluncus RepID=D0YPY2_9ACTO
          Length = 246

 Score =  129 bits (323), Expect = 8e-29,   Method: Composition-based stats.
 Identities = 41/241 (17%), Positives = 71/241 (29%), Gaps = 39/241 (16%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           + ST    +A  G DG GKST      + +  R                E ++     G 
Sbjct: 26  VRSTRGAFVAFEGTDGVGKSTQIKLAADWVKTRG--------------WEVVTTREPGGT 71

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYP 127
             GR LR       E               L +  RA    + ++     G ++I+DR+ 
Sbjct: 72  NLGRQLRELLLEAGETTVCEGQVAPRAEALLFAADRAQHVAELIVPALNAGKIVISDRFM 131

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK 187
              V      G  L      +  +                  P L + L +D + A+ R+
Sbjct: 132 ASSVAYQG-QGRDLGPKEIRDLSL-WA----------TGGLTPNLTVLLDLDPEIAWERQ 179

Query: 188 PDHQLA-----------ALQEKIA-VTPQLTFNGAKILELDGRHPADEILQASLRAIHAA 235
            + +               Q K+     +L       + +D     +EI       + + 
Sbjct: 180 QNDETRVSPDRMEGEGLEFQRKVRARFRRLAEENETWMVVDASLTPEEIAAQVRLRLASV 239

Query: 236 L 236
           L
Sbjct: 240 L 240


>UniRef50_A9BCY7 Thymidylate kinase n=9 Tax=Prochlorococcus marinus RepID=KTHY_PROM4
          Length = 215

 Score =  129 bits (323), Expect = 8e-29,   Method: Composition-based stats.
 Identities = 44/231 (19%), Positives = 76/231 (32%), Gaps = 33/231 (14%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
              I + G DG GKST  + +   L                    +I++ P  G   G+ 
Sbjct: 3   GHFIVLEGIDGCGKSTQISHISKWLPQSG--------LMPKNANLYITREPG-GTTLGKS 53

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVP 132
           LR    H HE             + L +  RA      +  K  +G  +I+DR+    + 
Sbjct: 54  LRDLLLHEHETNV----PAPLTELLLYAADRAEHIHSLIQPKLDKGDWVISDRFSGSTLA 109

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQL 192
              + G       G    I ++R+ +    Q     +P + I L I   T+  R+     
Sbjct: 110 ---YQG------FGRGLDINLIRRLDAIARQ---GLVPEITIFLKISVLTSMRRRAKKSA 157

Query: 193 AALQ-------EKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
             ++       +K+A       N    + ++G      +      AI   L
Sbjct: 158 DRMEAEGEGFLKKVASGFSRIANEEHWITIEGEQDQALVSDEIKLAITNKL 208


>UniRef50_C4KZW9 Thymidylate kinase n=1 Tax=Exiguobacterium sp. AT1b
           RepID=KTHY_EXISA
          Length = 212

 Score =  129 bits (323), Expect = 9e-29,   Method: Composition-based stats.
 Identities = 38/236 (16%), Positives = 71/236 (30%), Gaps = 44/236 (18%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
               I + G DGSGKST    LV  L  +                  +++ P  G   G 
Sbjct: 2   SGMFITVEGPDGSGKSTQLQLLVENLKQKGYDIV-------------VTREPG-GTTVGN 47

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEV 131
            +R                   + + L +  RA    + +    ++G +++ DR+    +
Sbjct: 48  QIREVLLSPDHHE-----MTPRVEMMLYAASRAQNVEQVIRPALERGAIVLCDRFIDASI 102

Query: 132 PGFRFDGPQLAKTTGGNGWI-KMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH 190
               + G  L         + +                 P L     ++ + A AR  D 
Sbjct: 103 A---YQGYGLQYDLDQIRSLNEWATN----------GLTPDLTFLFDLNPERASARMKDR 149

Query: 191 -QLAALQEKIAVTPQLTFNG---------AKILELDGRHPADEILQASLRAIHAAL 236
            QL  ++ +     +  + G          +I+ +D     + I    L      L
Sbjct: 150 GQLDRIESRDQAFHERVYAGFQTLLKQYPERIVRIDADQSIECIQDEVLDYTIERL 205


>UniRef50_Q8DHA4 Thymidylate kinase n=2 Tax=Cyanobacteria RepID=KTHY_THEEB
          Length = 241

 Score =  128 bits (322), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 38/241 (15%), Positives = 79/241 (32%), Gaps = 32/241 (13%)

Query: 7   SIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVI 66
           S  +      I + G +G+GK+T   ++   L        +        +   +++ P  
Sbjct: 3   SATHPYAGLFIVLEGGEGAGKTTQMGAIATWLENSGWLAKLRSCHVDPPL--LLTREPG- 59

Query: 67  GAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDR 125
           G P G+ LR    H      +         + L +  RA      +  + Q+G +++ DR
Sbjct: 60  GTPLGQGLRQLLLH------SDLAIDPLAELLLYAADRAQHVAMGIRPQLQRGGIVLCDR 113

Query: 126 YPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA 185
           Y    V    +         G    +++++         + +    L++ L +      A
Sbjct: 114 YTASTVAYQGY---------GRGLDLQIIQHINQMATGGLGA---DLVLWLDLPVAVGLA 161

Query: 186 RKPDHQL-AALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAA 235
           R         L++      +    G          +   +D   P D++ QA    + A 
Sbjct: 162 RTQQRGRGDRLEQNAVAFHERVRQGFLALAQQGSDRWQRIDADQPPDQVTQAIQECLAAH 221

Query: 236 L 236
           L
Sbjct: 222 L 222


>UniRef50_B3T390 Putative Thymidylate kinase n=1 Tax=uncultured marine crenarchaeote
           HF4000_ANIW97J3 RepID=B3T390_9ARCH
          Length = 292

 Score =  128 bits (322), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 41/238 (17%), Positives = 77/238 (32%), Gaps = 42/238 (17%)

Query: 4   RNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQL 63
           R + +  S  V +IAI G D +GK T T  LV  L                +I   +   
Sbjct: 90  RFLILRQSYSVLIIAIEGLDQAGKKTQTEMLVKALRRI-------------KIKTAVFSF 136

Query: 64  PVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLIT 123
           P      G+ +++  +     P         ++ YL +  R  K  ++   S +  +L+ 
Sbjct: 137 PDYSTIIGKEIKNHLSGKRNFP-------PEIIHYLYAANRLEKLEEIQKASSKNSVLVM 189

Query: 124 DRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTA 183
           +RY              L          K L++ E  L          L+I L   +  +
Sbjct: 190 NRYYHSN----------LVYGIANGLKEKWLQKLEEGL------PKADLVIVLDASQDDS 233

Query: 184 FARKPD-----HQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
           F+RK        +     +KI+   +      +   +          +  ++ I   +
Sbjct: 234 FSRKKSKRDRFEKNKNFSKKISRIYRRLAKKHRWKMV-SSDTKQNTHKEIMKIISKKI 290


>UniRef50_UPI0001AECAE5 thymidylate kinase n=6 Tax=Streptomyces RepID=UPI0001AECAE5
          Length = 1095

 Score =  128 bits (321), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 41/236 (17%), Positives = 77/236 (32%), Gaps = 42/236 (17%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           +     IA+ G DG+GKST   +L   + A+                  +++ P    P 
Sbjct: 496 AATGFFIALEGGDGAGKSTQAEALAEWIRAKGHEVV-------------VTREPGA-TPI 541

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQV 129
           G+ LR+    V        G        L +  RA      +    ++G ++I+DRY   
Sbjct: 542 GKRLRAILLDVSS-----AGLSHRAEALLYAADRAEHVDTVVRPALERGAVVISDRYIDS 596

Query: 130 EVPGFRFDGPQLA-KTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-- 186
            V    + G       T      +                +P L + L +  +TA  R  
Sbjct: 597 SVA---YQGAGRDLAPTEIARISRWA----------TGGLVPHLTVLLDVSPETARERFT 643

Query: 187 ----KPDHQLAALQEKIA--VTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
               + + + AA  +++          +  + L +D     +E+       +   L
Sbjct: 644 EAPDRLESEPAAFHQRVRAGFLTLAAADQDRYLVVDAGQQPEEVTTVVRHRLDQLL 699


>UniRef50_Q4UE21 Thymidylate kinase, putative n=2 Tax=Theileria RepID=Q4UE21_THEAN
          Length = 214

 Score =  128 bits (320), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 29/226 (12%), Positives = 63/226 (27%), Gaps = 31/226 (13%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
              ++I   G D SGKST    L  +L+                +  +  +    G    
Sbjct: 7   LRGKLIVFEGIDRSGKSTQINLLSQKLSEE---------NIKNEVLSFPYKTTPTGKLLR 57

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEV 131
            YLR++                  +  L S  R     +++   + G  +ITDRY    +
Sbjct: 58  EYLRNR----------DESIPKQALHLLFSANRWEVMNRIIKLLKSGTHVITDRYAFSGI 107

Query: 132 PGFRFDGPQ--LAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK-- 187
                   +    +              +  + +      P ++  + +  + + AR   
Sbjct: 108 AYSVGAEVRLLFYQVFPQGLDFNWCLIPDTGIVE------PDVVFYMDLAPECSSARGNF 161

Query: 188 --PDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRA 231
               ++     E +    +   N +    +       +I       
Sbjct: 162 GSEIYENLEHMENVYEVFKRFGNLSYWNIIKAHDDQKQIHHKIYSI 207


>UniRef50_B8HXT9 Thymidylate kinase n=8 Tax=Cyanobacteria RepID=KTHY_CYAP4
          Length = 234

 Score =  128 bits (320), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 36/239 (15%), Positives = 72/239 (30%), Gaps = 33/239 (13%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            ++I   G +GSGK+T        L +      +     +      +++ P  G   G  
Sbjct: 3   GKLIVFEGGEGSGKTTQLQRSRQWLESSGWLARLQQTLPTLAKPLLVTREPG-GTALGIK 61

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQVEVP 132
           LR    +   +        +   + L +  RA     ++    + G L++ DR+    V 
Sbjct: 62  LRQLLLNSDPEDV----IQSRTELLLFAADRAQHVATRLQPHLEAGGLILCDRFTDSTVA 117

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH-- 190
              +         G    + ++ Q        + S    L + L +D +    R      
Sbjct: 118 YQGY---------GRGLSLALIDQLNQIATDGLTS---DLTLWLDLDVEMGLERSRQRLQ 165

Query: 191 ----QLAALQEKIAVTPQLTFNG---------AKILELDGRHPADEILQASLRAIHAAL 236
                L  ++       Q    G          +I+ +D   P   +     R +   L
Sbjct: 166 QSGGGLDRIERGEIAFHQRVQQGFRALSQAAPERIVTIDASQPEAMVADKIQRILEEKL 224


>UniRef50_B6AIV4 Thymidylate kinase family protein n=1 Tax=Cryptosporidium muris
           RN66 RepID=B6AIV4_9CRYT
          Length = 208

 Score =  127 bits (319), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 35/229 (15%), Positives = 60/229 (26%), Gaps = 39/229 (17%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
               +I   G D SGK+  +  L  +               +  +  +  +   IG    
Sbjct: 2   RRGALIVFEGTDRSGKTLQSNKLAEKFKNE---------NINCILIGFPDRSTNIGYLLD 52

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEV 131
            YLR+                  +   L S  R   F K+    + G  +I DRY    V
Sbjct: 53  LYLRN-----------CENMRPEVSHLLFSANRWEYFEKIKTYLESGVTVICDRYAFSGV 101

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK---- 187
                              I+     E  L        P ++  L  D Q    R     
Sbjct: 102 AY---------SVGALKKDIEWCMMPEKGLIS------PDIVFFLDADVQIRVDRSGFGD 146

Query: 188 PDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
             +   + Q  ++              +D     +++ +        AL
Sbjct: 147 ERYDTESTQNSVSTIYSQFKKYDYWKVIDASKDPNDVFENIYNFAKQAL 195


>UniRef50_D2Q7V9 Thymidylate kinase n=2 Tax=Bifidobacterium dentium
           RepID=D2Q7V9_9BIFI
          Length = 252

 Score =  126 bits (317), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 37/226 (16%), Positives = 66/226 (29%), Gaps = 23/226 (10%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
              I+  G DG GK+T    L   + A+     +        +G  I  + + G      
Sbjct: 12  GMFISFEGVDGVGKTTQVERLRAHIEAQGRECVVTREPGGTALGVAIRGMLLHGVAAADA 71

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVP 132
                     +   P          L +  RA    + +    ++G ++ITDRY    + 
Sbjct: 72  GVPANKADGGRQPEPADIAPRTEALLFAADRAQHVAEVIRPALERGAVVITDRYLDSSLA 131

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQL 192
                         G   + +   R+L L+       P     L +D   + AR   H  
Sbjct: 132 YQA-----------GGRELTLKEIRDLSLWATNGLL-PERTYLLDMDPAASHARL-RHSE 178

Query: 193 AALQEKIAVTPQLTFN---------GAKILELDGRHPADEILQASL 229
             ++         T N           +   +D     +E+ Q   
Sbjct: 179 DRMESAGDDFQNRTRNAFLELARAEPERFRVIDASQSIEEVWQRIE 224


>UniRef50_Q115I0 Thymidylate kinase n=10 Tax=Bacteria RepID=KTHY_TRIEI
          Length = 225

 Score =  126 bits (317), Expect = 5e-28,   Method: Composition-based stats.
 Identities = 34/221 (15%), Positives = 70/221 (31%), Gaps = 26/221 (11%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I   G +G GK+T    L + L     +  I        +   I++ P  G   G+ 
Sbjct: 3   GKFIVFEGVEGGGKTTQIELLQDWLLETGESRQILPKSIDLDLEVVITREPG-GTKLGKA 61

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQVEVP 132
           LR                     + L +  RA      +    ++G +++ DR+    + 
Sbjct: 62  LRELLLSPDVLAEKIQETS---ELLLYAADRAQHIEALIKPCLERGTIVLCDRFIDSTIA 118

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP---- 188
              +         G    +++++Q     Y         L   L ID +   AR      
Sbjct: 119 YQGY---------GRGLDVELIKQLN---YIATGGLKSDLTFWLDIDVEIGLARAKSRGN 166

Query: 189 ----DHQLAALQEKIAV-TPQLTFNGAKILELDGRHPADEI 224
               +        ++     +L  N + I+ +D     +++
Sbjct: 167 FDRMEQANIEFHRRVQQGYQELAKNNSLIVRIDANLTREKV 207


>UniRef50_Q54GN2 Thymidylate kinase n=1 Tax=Dictyostelium discoideum
           RepID=KTHY_DICDI
          Length = 222

 Score =  126 bits (317), Expect = 5e-28,   Method: Composition-based stats.
 Identities = 36/224 (16%), Positives = 62/224 (27%), Gaps = 39/224 (17%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
                I   G D  GKST   SL N ++         + +   +   +  +   IG    
Sbjct: 17  KRGLFILFEGVDRVGKSTQVQSLTNHISN--------VQKLPTKSLRFPDRTTPIGQIIN 68

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEV 131
           +YL++                   +  L S  R      +L     G  ++ DRY     
Sbjct: 69  QYLQNAT-----------NMDDRALHLLFSSNRWEARDSILELLNNGTNIVVDRYSYS-- 115

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----K 187
                    +A +             E  L        P L+  L +  + A  R     
Sbjct: 116 --------GVAYSAAKGIDFDWCYACEKGL------PKPDLIFYLSMSSEDATKRGEYGG 161

Query: 188 PDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRA 231
             ++    Q+KI    +      +   ++     DEI       
Sbjct: 162 ERYEKLEFQKKIKQIYEEKLVDDQWKIINANRSIDEISNEISSI 205


>UniRef50_Q6AJE2 Thymidylate kinase n=1 Tax=Desulfotalea psychrophila
           RepID=KTHY_DESPS
          Length = 202

 Score =  126 bits (316), Expect = 6e-28,   Method: Composition-based stats.
 Identities = 39/236 (16%), Positives = 74/236 (31%), Gaps = 45/236 (19%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           +++ P ++I   G DG+GKST    L N L ++          ++G  G+ I QL     
Sbjct: 1   MSNNPGKLIIFEGTDGAGKSTQIKMLANYLRSKGLDVIASFEPTNGPYGQKIRQLYTDRN 60

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQ 128
              R                       +   L+  R +  + +      G +++ DRY  
Sbjct: 61  KVTR--------------------NEELELFLADRREHVNKLINPAISAGKIVLCDRYYL 100

Query: 129 VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP 188
                    G                   E  L +   +  P L + L I  +    R  
Sbjct: 101 STAAYQGALG----------------FDVEEILQRNSFAPTPDLALLLQIPVEDGRRRIT 144

Query: 189 --------DHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                   D + A + EK++     + +   I  ++     D + +  +  +   L
Sbjct: 145 SSRGEETNDFEKAEMLEKVSTIFN-SLSFPYIRHINACQSIDNVQRDIIMQVKQLL 199


>UniRef50_Q2JR37 Thymidylate kinase n=4 Tax=Bacteria RepID=KTHY_SYNJA
          Length = 204

 Score =  126 bits (316), Expect = 6e-28,   Method: Composition-based stats.
 Identities = 35/229 (15%), Positives = 66/229 (28%), Gaps = 41/229 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G +G GK+T  A L   L                 +GE + +L + G P      
Sbjct: 2   FITLEGGEGVGKTTQQALLAERLQREGYACVSTREPGGTALGEALRELLLHGDPL----- 56

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEVPGF 134
                                + L +  RA    + +      G ++I DR+    +   
Sbjct: 57  ----------------TPLAELLLYAADRAEHVNKVIAPALAVGQVVICDRFTDSTLAYQ 100

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-----KPD 189
            +         G    ++ +RQ             P L + L +  +   AR     K +
Sbjct: 101 GY---------GRGLNLEQIRQLNHLA---TGGLQPQLTLWLDLAPEVGLARSRLGDKLE 148

Query: 190 HQLAALQEKIAVTPQ--LTFNGAKILELDGRHPADEILQASLRAIHAAL 236
            +      ++    Q        +I+ +D      E+       +   L
Sbjct: 149 QEHLEFHRRVYRGFQALAAAEPQRIVRIDAGGSPLEVAARIWSVVKPRL 197


>UniRef50_Q1D6W4 Thymidylate kinase n=7 Tax=Cystobacterineae RepID=Q1D6W4_MYXXD
          Length = 221

 Score =  126 bits (316), Expect = 6e-28,   Method: Composition-based stats.
 Identities = 42/237 (17%), Positives = 75/237 (31%), Gaps = 43/237 (18%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
           P R I + G DG+G +T    L   L A   +                ++ P  G P G 
Sbjct: 13  PGRFIVLEGLDGAGTTTQVERLAAALRAEGHSV-------------LTTREPSDG-PVGT 58

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEV 131
            +R         P          +  L +  R      ++L     G +++ DRY    +
Sbjct: 59  MIRQALTGRLGLPGGAGPLAPETLALLFAADRTDHLTARVLPALAAGQIVLCDRYVLSSL 118

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH- 190
               + G  L         ++ +               P L + +G+  + A  R+    
Sbjct: 119 A---YQGASLP--------MEWVEAVNACAVS------PDLTLFVGVAPEVAARRRKARG 161

Query: 191 ------QLAALQEKIAVTP----QLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
                 +    Q +IA       +      +I+ +DG    + +  ASL  I   L+
Sbjct: 162 GAAELFEADEAQRRIAKQYVAAIRRREKHERIVHIDGEQGIEAVTAASLVEIRKLLA 218


>UniRef50_B5YJ17 Thymidylate kinase n=1 Tax=Thermodesulfovibrio yellowstonii DSM
           11347 RepID=B5YJ17_THEYD
          Length = 209

 Score =  126 bits (316), Expect = 7e-28,   Method: Composition-based stats.
 Identities = 37/233 (15%), Positives = 65/233 (27%), Gaps = 43/233 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G +GSGK+T    L  +L                  G  I ++ +          
Sbjct: 6   FITFEGIEGSGKTTQGKLLAEKLKKEGLKVLYTYEPGDTEAGRHIRKILLN--------- 56

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEVPGF 134
                      +         + L    R      K+    + GF++I DR+    +   
Sbjct: 57  -----------SEIKINPLCELLLYFADRVQHIEEKIKPCIESGFIVICDRFTDSTLVYQ 105

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-----KPD 189
            +              I +++Q    +       +P L + L         R     K D
Sbjct: 106 GY---------ARGISIDLIKQLNKIVLDEF---MPDLTVLLDCPANIGLKRNQKINKKD 153

Query: 190 H---QLAALQEKIAVTPQLTFN--GAKILELDGRHPADEILQASLRAIHAALS 237
               +  A  EK+             +   LD     D+I +   R + + LS
Sbjct: 154 RFEMENLAFHEKVRQGYLKLAELYKKRFFVLDATESIDKIAEDIYRKVKSILS 206


>UniRef50_O81650 Thymidylate kinase (Fragment) n=1 Tax=Arabidopsis thaliana
           RepID=O81650_ARATH
          Length = 188

 Score =  126 bits (315), Expect = 8e-28,   Method: Composition-based stats.
 Identities = 39/188 (20%), Positives = 62/188 (32%), Gaps = 40/188 (21%)

Query: 21  GCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLRSKAAH 80
           G D SGKST  A L++ L                 +  +  +   +G     YL +K+  
Sbjct: 2   GLDRSGKSTQCAKLLSFLNGLGH---------PTELWRFPDRETSVGQMISAYLSNKS-- 50

Query: 81  VHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFRFDGPQ 140
                          +  L S  R  K   M  K + G  LI DRY              
Sbjct: 51  ---------QLDDHTIHLLFSANRWEKRSLMEEKLKTGTTLIVDRYSYS----------G 91

Query: 141 LAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK----PDHQLAALQ 196
           +A ++     I+  +  E+ L        P  ++ L I  + A  R       ++    Q
Sbjct: 92  VAFSSAKGLDIEWCKAPEIGL------LAPDSVLYLDISPERAAERGGYGDERYERVEFQ 145

Query: 197 EKIAVTPQ 204
           +K+A   Q
Sbjct: 146 KKVADFYQ 153


>UniRef50_D2MMU9 dTMP kinase n=1 Tax=Bulleidia extructa W1219 RepID=D2MMU9_9FIRM
          Length = 225

 Score =  125 bits (314), Expect = 9e-28,   Method: Composition-based stats.
 Identities = 44/232 (18%), Positives = 79/232 (34%), Gaps = 41/232 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I I G DGSGKST++ ++   L        + L +  G            G+     +R
Sbjct: 21  FITIEGPDGSGKSTVSQTVCQRLQQEGY--RLQLTREPG------------GSKIAEQIR 66

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           S        P     +     +   +  R +   K+L   + G  +I+DR+    +    
Sbjct: 67  SIILD----PQNTDMDARTEALLYAASRRQHLMDKVLPALENGIPVISDRFVDSSLA--- 119

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR--KPDHQLA 193
           + G               L          +   LP   I L ID +T   R  K  +QL 
Sbjct: 120 YQGVGRCIGIEP----VWLINEFA-----IEGCLPDKTIYLDIDAETGLRRIQKGRNQLD 170

Query: 194 ALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAAL 236
            L ++ A      F G          + +++D R   +++++ +   +   L
Sbjct: 171 RLDQEEASFHTRVFQGYQTILKRFPDRFIKVDARQGLEKVVEDTYVVLKGLL 222


>UniRef50_C4R413 Thymidylate and uridylate kinase n=1 Tax=Pichia pastoris GS115
           RepID=C4R413_PICPG
          Length = 202

 Score =  125 bits (314), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 38/227 (16%), Positives = 73/227 (32%), Gaps = 49/227 (21%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
             +I I G D +GKST TA L + L                    ++ + P    P G+ 
Sbjct: 3   APLIVIEGLDRTGKSTQTAKLCHRLNG------------------FLVKFPNRETPIGKL 44

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           L                    +   L S  R    + +     +G  ++ DRY       
Sbjct: 45  LNQYLTDASN------PMPLEVAHLLFSANRWEMVKNIEDLLSKGTPVVMDRYVYS---- 94

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGI-DEQTAFAR----KP 188
                  +A +      I+     +  L        P + I L   D  +   R    + 
Sbjct: 95  ------GVAYSMAKGLDIEWCLAPDKGL------PKPDVTIFLKANDLDSISQREGFGEE 142

Query: 189 DHQLAALQEKIAVTPQLTFNGA---KILELDGRHPADEILQASLRAI 232
            +++A+LQ  +    ++  +     K++ +DG    D++ +     +
Sbjct: 143 RYEVASLQTSVRNNFEILRSRYDEWKVIIIDG-KDIDQVHEHIWELV 188


>UniRef50_A5DF16 Putative uncharacterized protein n=3 Tax=Saccharomycetales
           RepID=A5DF16_PICGU
          Length = 215

 Score =  125 bits (313), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 40/230 (17%), Positives = 70/230 (30%), Gaps = 39/230 (16%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
             +I I G D SGK+T T  L N +              S  + ++  +   IG    +Y
Sbjct: 3   GHLILIEGLDRSGKTTQTQILHNAIP-------------SSSLIKFPDRSTNIGTIINQY 49

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           L      + ++ +            L S  R      +  + Q G  +I DRY    +  
Sbjct: 50  LTDHNFSLSDQAA----------HLLFSANRWELAASIEDQLQAGHTVIMDRYIYSGIAY 99

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLA 193
                     ++     ++ L   +  L        P + I L +D     ARK   +  
Sbjct: 100 SLAKSE--TSSSPEMASVEWLYAPDRGL------PKPDVTIFLTLDIAEMAARKSWGEER 151

Query: 194 ALQEKIAVTPQLTF-------NGAKILELDGRH-PADEILQASLRAIHAA 235
             Q K     +  F           ++ +D      DE+       +   
Sbjct: 152 YEQTKFQEVVKRCFLKVLDPHADPSVVIVDVNKLGIDEVASKIWTVVEER 201


>UniRef50_B7GT80 Thymidylate kinase n=2 Tax=Actinobacteridae RepID=KTHY_BIFLI
          Length = 233

 Score =  125 bits (313), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 37/234 (15%), Positives = 68/234 (29%), Gaps = 39/234 (16%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
               ++  G DG GK+T    L   L A+  T  +        +G+ I QL + G     
Sbjct: 2   SGLFVSFEGVDGVGKTTQVERLRAYLEAQGRTVVVTREPGGTVLGKAIRQLLLHG----- 56

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEV 131
                                     L +  RA    + +    ++G ++ITDRY    +
Sbjct: 57  -----------VDGGAVDIAPRAEALLFAADRAQHVAETIRPALERGEVVITDRYLDSSL 105

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQ 191
                 G +L      +  +               + LP     L +D   +  R  +H 
Sbjct: 106 AYQA-GGRELTPEEIRSLSM-WATN----------NLLPDRTYLLDMDPALSHNRL-EHA 152

Query: 192 LAALQEKIAVTPQLTF---------NGAKILELDGRHPADEILQASLRAIHAAL 236
              ++   +     T             +   +D     +++  A    I   L
Sbjct: 153 EDRMESAGSDFQSRTRQAFLDLAAAEPNRFHVIDASQSIEQVWSAIEADIQTLL 206


>UniRef50_B5YD95 Thymidylate kinase n=1 Tax=Dictyoglomus thermophilum H-6-12
           RepID=B5YD95_DICT6
          Length = 205

 Score =  124 bits (312), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 32/226 (14%), Positives = 70/226 (30%), Gaps = 39/226 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G DGSGK+T    L + L ++    ++        +G  I ++ +          
Sbjct: 6   FITFEGIDGSGKTTQAILLKDYLESKGFKVYLTREPGGTEVGSKIREILLSPDF------ 59

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                                ++L    R      +  K ++ +++I +RY    +    
Sbjct: 60  --------------SINPWTEVFLYLASRVENTIVVKKKLEENYIVICERYADSTIAYQG 105

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
           +         G N  + +L +         +   P L + + +D + A  RK       +
Sbjct: 106 Y---------GRNLPLNILAEMNDIA---TSGLKPDLTVLIDLDPELALRRKKTFDRIEM 153

Query: 196 QEK-------IAVTPQLTFNGAKILELDGRHPADEILQASLRAIHA 234
           + K                   + + + G    +EI +  ++ I  
Sbjct: 154 EGKDFYYRVREGYLEIAKREQERFIIIPGSLSKEEIFERIVKRIKE 199


>UniRef50_B0K7K7 Thymidylate kinase n=20 Tax=Firmicutes RepID=KTHY_THEP3
          Length = 203

 Score =  124 bits (312), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 36/234 (15%), Positives = 71/234 (30%), Gaps = 44/234 (18%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I+  G DG GK+T    L   L  +                  + + P  G   G  
Sbjct: 3   GKFISFEGIDGCGKTTQIKFLEEYLLKQGY-------------NILVLREPG-GTKVGEK 48

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEVP 132
           +R      +              + L +  RA     K+L   ++G +++ DR+      
Sbjct: 49  VRDILLDKNNF------ISPVTEMLLYASSRAQLVEEKILPAIEEGKIVLLDRFVDSSYV 102

Query: 133 GFRF-DGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQ 191
              +  G  + K    N    M               LP + I + I  + A  R+   +
Sbjct: 103 YQGYARGLGIEKVKVVNEIATM-------------GILPDVTIYIDITPEEAMKRRGKRE 149

Query: 192 LAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAAL 236
              L+ +     +    G          + + +DG     ++ +  +  +   L
Sbjct: 150 ADRLERESWDFHKKVREGYIKLVKEFPKRFVFIDGMQELMKVHKDIIDVVKKYL 203


>UniRef50_B3SBN8 Putative uncharacterized protein n=2 Tax=Metazoa RepID=B3SBN8_TRIAD
          Length = 211

 Score =  124 bits (311), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 41/233 (17%), Positives = 70/233 (30%), Gaps = 42/233 (18%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
            +     +I I G D +GKST +  LV+ L A               + ++  +   IG 
Sbjct: 3   TDRNRGALIIIEGGDRTGKSTQSKMLVDALLADG---------KQAELVKFPDRTTPIGK 53

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQ 128
             G YL+                    +  + S  R  K   ++ + + G  L+ DRY  
Sbjct: 54  LAGSYLQKTL-----------DLEDHAIHLIFSANRWEKVPSIIERLENGITLVVDRYAF 102

Query: 129 VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK- 187
             V                   I+  +Q +  +        P L+I L +    A +R  
Sbjct: 103 SGVAYTS---------AKRGFDIEWCKQSDTGI------PAPDLVIYLTLPVDQATSRDQ 147

Query: 188 -PDHQLAALQ---EKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
               +  + Q     +    +L         LD     D I Q         +
Sbjct: 148 YGTERYESTQFQKRAVENFEKLMTK--NWTTLDASQSIDAIHQQMKDLTTEIM 198


>UniRef50_UPI000186EA7B thymidylate kinase, putative n=1 Tax=Pediculus humanus corporis
           RepID=UPI000186EA7B
          Length = 601

 Score =  124 bits (311), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 38/238 (15%), Positives = 61/238 (25%), Gaps = 59/238 (24%)

Query: 5   NMSIINST--PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQ 62
           N ++ NS   P  +I   GCD +GK+T    LV +L                        
Sbjct: 405 NNTLTNSDNLPGALIVFEGCDRAGKTTQCKKLVEKLNELGIKSQFMQFPED--------- 455

Query: 63  LPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLI 122
                                            V  L S  R     KM+    +   LI
Sbjct: 456 ----------------------------LNDQTVHLLFSANRWENQPKMVKLLHEEVTLI 487

Query: 123 TDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQT 182
            DRY    V                    K   + E+ L        P L+  L +    
Sbjct: 488 VDRYSFSGVAYSA---------AKPGMDFKWCYKPEIGL------PKPDLVFLLYVPVNV 532

Query: 183 AFAR----KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
              R    +  ++    Q+ +     +         +D     +EI +  L+     +
Sbjct: 533 LKKRIGFGEERYENNDFQQSVFDNY-IKMKDDTWHLIDASKNINEIHEDILKQTQRII 589


>UniRef50_UPI0001BC2C76 thymidylate kinase n=1 Tax=Brevibacterium linens BL2
           RepID=UPI0001BC2C76
          Length = 904

 Score =  124 bits (311), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 53/250 (21%), Positives = 77/250 (30%), Gaps = 48/250 (19%)

Query: 2   NQRNMSIINSTP----VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIG 57
           N  N SI NS         IAI G DGSGKST    +   LA    +             
Sbjct: 396 NGANDSIGNSAERLGAGFFIAIEGGDGSGKSTQIKRVSQILADEGYSV------------ 443

Query: 58  EWISQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQ 116
              ++ P  G   GR +RS                      L +  RA+     +     
Sbjct: 444 -EATREPG-GTELGRQIRSVLFD-------SEPPSPRTEALLFAADRAHHVASLVDPSLD 494

Query: 117 QGFLLITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRL 176
            G ++ITDRY    +      G      T      K   Q            +P L I L
Sbjct: 495 SGNIVITDRYIDSTIAYQAA-GRNFDPKTILALS-KWATQ----------GLVPHLTIVL 542

Query: 177 GIDEQTAFARKP--------DHQLAALQEKIAVTP--QLTFNGAKILELDGRHPADEILQ 226
            ID + +  R          D +     +++  T   +      + + LD     +++  
Sbjct: 543 DIDPEVSATRMGKRGENNYLDEENQQFHQRVRQTYLTRAHKEPDRYIVLDASVSEEDLTA 602

Query: 227 ASLRAIHAAL 236
             L AI   L
Sbjct: 603 EILTAIRTRL 612


>UniRef50_A9DXA8 Thymidylate kinase n=1 Tax=Kordia algicida OT-1 RepID=A9DXA8_9FLAO
          Length = 206

 Score =  124 bits (310), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 41/236 (17%), Positives = 75/236 (31%), Gaps = 50/236 (21%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            IAI G DGSGKST   ++   L A     ++    +  RIG+ I  +            
Sbjct: 6   FIAIEGIDGSGKSTQAKNIAKRLEAEGHKVYLTFEPTDMRIGKMIRSILGGQEKADEK-- 63

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK----MLCKSQQGFLLITDRYPQVEV 131
                              ++  L    R          +L K  +G+ +ITDRY     
Sbjct: 64  -------------------VIAALFVADRLDHILHETNGILKKLAEGYTVITDRYYFSS- 103

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR----- 186
             + + G  +         +  + Q             P + I + +  + A  R     
Sbjct: 104 --YAYHGAHM--------DMDWVIQSNKMAAD---ILKPTVNIFVDVSPEVAMKRINANR 150

Query: 187 ------KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                 +    L A+Q +     +   +   I++++G    + + +A    I   L
Sbjct: 151 ETVEIYETLDNLKAVQSQYLQAFKKLQHEENIVKVNGDETPENVTEALWNIIQQEL 206


>UniRef50_C8W2Q7 Thymidylate kinase n=1 Tax=Desulfotomaculum acetoxidans DSM 771
           RepID=C8W2Q7_DESAS
          Length = 233

 Score =  123 bits (309), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 32/245 (13%), Positives = 61/245 (24%), Gaps = 44/245 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
              I   G DGSGK+T    L   L      ++   G     +          G      
Sbjct: 3   GVFIVFEGIDGSGKTTQINILYKNLLQHNRIKNQPAGSEYVLLTREP-----GGTATSEL 57

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVP 132
           +R+   +                  L +  RA    + +      G ++I DR+    + 
Sbjct: 58  IRNILLNPAN-----DKLCARTEALLYAAARAQHVEERIRPALSSGKIVICDRFIDSSLA 112

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH-- 190
              +         G    +  L               P L I L +    A  R  +   
Sbjct: 113 YQGY---------GRGQDLSFLHNLNQLA---AGGLKPDLTILLDLPVGAALKRLNNRQV 160

Query: 191 ---QLAALQEKIAVTPQLTFNGA----------------KILELDGRHPADEILQASLRA 231
              +   L+ +     +    G                   L ++     +++    +  
Sbjct: 161 SGIEKDRLESEAVSFYERVREGYLKIAGTGIDNNSAGSGGYLVVNADQELNKVSDRIIDG 220

Query: 232 IHAAL 236
           +   L
Sbjct: 221 VGNCL 225


>UniRef50_A5FR84 Thymidylate kinase n=5 Tax=Dehalococcoides RepID=KTHY_DEHSB
          Length = 208

 Score =  123 bits (309), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 39/231 (16%), Positives = 70/231 (30%), Gaps = 41/231 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G +G GKST + +L   L  +     +       + G+ I++L            
Sbjct: 4   FITFEGGEGCGKSTQSKALYRYLKKKGLGCVLTHEPGGSKSGDKITRLLKWSK------- 56

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
                                + L +  R+      +    Q G ++I DRY    +   
Sbjct: 57  ------------EEHISPLTELLLFNASRSILIDNVIKPALQDGKIVICDRYTDSTLAYQ 104

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
            +         G    +  ++             +P L I L +D++ A  RK +     
Sbjct: 105 GY---------GRGLDLDTVKCVNSLAS---GGLVPDLTIWLDMDDKAALLRKGELPPDR 152

Query: 195 LQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAAL 236
            + +     Q   NG          + L+LD   P  EI     + +   L
Sbjct: 153 FESENNGFHQRVRNGFGAIYATEPDRFLKLDASLPQSEIFSRIKQRVTILL 203


>UniRef50_Q3A3X3 Thymidylate kinase n=3 Tax=Deltaproteobacteria RepID=KTHY_PELCD
          Length = 216

 Score =  123 bits (308), Expect = 5e-27,   Method: Composition-based stats.
 Identities = 37/239 (15%), Positives = 68/239 (28%), Gaps = 48/239 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I++ G +GSGK+T    L + L +                   I++ P  G P    +R
Sbjct: 4   FISLEGIEGSGKTTQIKRLADRLESLGHAV-------------LITREPG-GCPIADQIR 49

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
               H                + L +  RA    + +     QG +++ DRY    +   
Sbjct: 50  QILLHPDNG-----HLDPKAELLLYAAARAQHVAEVIRPALDQGKIVLCDRYCDATLAYQ 104

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP------ 188
            +              + M++Q          +  P L + L +       R        
Sbjct: 105 GY---------ARGLDLPMVKQLNELA---AGNCRPHLTLLLDMPHDRGLLRARSRNALG 152

Query: 189 --------DHQLAALQEKIA--VTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
                   + +  A   K+             +I  +D     DE+          AL+
Sbjct: 153 AGPEEGRFEQESLAFHNKVRQGYLDLARQEPQRIKVVDANGTLDEVCHRIWLTTSNALN 211


>UniRef50_Q254L6 Thymidylate kinase n=13 Tax=Chlamydiaceae RepID=KTHY_CHLFF
          Length = 207

 Score =  123 bits (308), Expect = 5e-27,   Method: Composition-based stats.
 Identities = 52/231 (22%), Positives = 80/231 (34%), Gaps = 40/231 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I I GC+GSGKS+LT  L N L     +                ++ P  G+P G  +R
Sbjct: 2   FIVIEGCEGSGKSSLTELLKNRLITEGKSV-------------IATREPG-GSPLGEQVR 47

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEVPGF 134
           +          + PG      ++L    RA     K++   + G ++I DR+    +   
Sbjct: 48  NWIL-----NPSLPGISPYTELFLFLASRAQHITEKIIPALESGKIVICDRFHDSTI--- 99

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQ-LA 193
            + G  +A+  G      +              +LP L   L I   T   RK   + L 
Sbjct: 100 VYQG--IAEGLGKEYVTNLCHHV-----VGEKKFLPDLTCLLDIPVDTGIKRKQQQKSLD 152

Query: 194 ALQEKIAVTPQLTFNG---------AKILELDGRHPADEILQASLRAIHAA 235
             ++K  V       G            L LDGR P +  L   + A    
Sbjct: 153 KFEDKPLVYHNKIREGFLSLAEANPENYLILDGRQPLEASLNKVMTAYTEL 203


>UniRef50_P00572 Thymidylate kinase n=11 Tax=Saccharomycetaceae RepID=KTHY_YEAST
          Length = 216

 Score =  123 bits (307), Expect = 7e-27,   Method: Composition-based stats.
 Identities = 36/236 (15%), Positives = 72/236 (30%), Gaps = 47/236 (19%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            ++I I G D +GK+T    L  +L              + ++ ++  +   IG     Y
Sbjct: 5   GKLILIEGLDRTGKTTQCNILYKKLQ------------PNCKLLKFPERSTRIGGLINEY 52

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           L   +  + ++           +  L S  R     K+     +G  ++ DRY    V  
Sbjct: 53  LTDDSFQLSDQA----------IHLLFSANRWEIVDKIKKDLLEGKNIVMDRYVYSGVAY 102

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRL---GIDEQTAFARKPDH 190
               G            +    Q ++ L        P L + L    +D     +   D 
Sbjct: 103 SAAKGT-------NGMDLDWCLQPDVGL------LKPDLTLFLSTQDVDNNAEKSGFGDE 149

Query: 191 QLAALQEKIAVTP--------QLTFNGAKILELD-GRHPADEILQASLRAIHAALS 237
           +   ++ +  V          ++      I  +D       E+     + +   LS
Sbjct: 150 RYETVKFQEKVKQTFMKLLDKEIRKGDESITIVDVTNKGIQEVEALIWQIVEPVLS 205


>UniRef50_Q9C2R7 Related to thymidylate kinase n=1 Tax=Neurospora crassa
           RepID=Q9C2R7_NEUCR
          Length = 309

 Score =  122 bits (306), Expect = 8e-27,   Method: Composition-based stats.
 Identities = 38/193 (19%), Positives = 63/193 (32%), Gaps = 37/193 (19%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
             +I I G D SGK+T    L +                      +  +   IG     Y
Sbjct: 24  GALIVIEGLDRSGKTTQVKLLEDRFLKAGKKVK---------TMRFPDRTTPIGQMIDSY 74

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           L+S+A                ++  L S  R    +K+  +  QG  LI DRY    +  
Sbjct: 75  LKSQA-----------QMDDHVIHLLFSANRWEAVKKITSELSQGTTLILDRYYHSGIVY 123

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK----PD 189
                         +  +   R  E+ L        P L++ L +DE+ A  R       
Sbjct: 124 SA-------AKQNPSLSLSWARAPEIGL------PRPDLVLFLDLDEEQARLRGGWGHEL 170

Query: 190 HQLAALQEKIAVT 202
           ++ A +Q ++   
Sbjct: 171 YEKAEMQRRVREL 183


>UniRef50_A7VTJ2 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A7VTJ2_9CLOT
          Length = 222

 Score =  122 bits (306), Expect = 9e-27,   Method: Composition-based stats.
 Identities = 35/241 (14%), Positives = 63/241 (26%), Gaps = 40/241 (16%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            ++I + G DGSGK+T T  L   L +R                  + ++ +        
Sbjct: 4   GKLIVMEGLDGSGKATQTGLLCQYLESRGRRVRHIEFPDYREPSSALVKMYLN------- 56

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEVP 132
                    E  S P            +  R   F R        G  ++ DRY      
Sbjct: 57  --------KEFGSNPGDVNAYAASSFYAVDRYASFLRFWRKDYLSGATIVADRYTTSNAV 108

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF-------- 184
                  +       N ++  L+  E   Y  +    P L++ L +  + +         
Sbjct: 109 YQM----EKTPREDWNKYLAWLQDYE---YGKLQLPRPDLVLFLDMPTEISQRLLSGRYA 161

Query: 185 --ARKPD--HQLAALQEKIAVTPQLTFNGAKILELD-----GRHPADEILQASLRAIHAA 235
              RK D          +   T            +           ++I +     +   
Sbjct: 162 GDERKKDLHESNVEFLTRCRRTALYAAEAMGWHTVSCSQEGAPRKIEDIQRDIREIVSQK 221

Query: 236 L 236
           L
Sbjct: 222 L 222


>UniRef50_D2E8C8 ORF77 n=1 Tax=Anguillid herpesvirus 1 RepID=D2E8C8_9VIRU
          Length = 214

 Score =  122 bits (306), Expect = 9e-27,   Method: Composition-based stats.
 Identities = 39/227 (17%), Positives = 66/227 (29%), Gaps = 47/227 (20%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVN-ELAARMPTEHIYL-GQSSGRIGEWISQLPVIGAPFG 71
            R+IA+ GCD +GKSTL A L      +        + G  +G +     + P + +   
Sbjct: 16  GRLIAVEGCDRTGKSTLCARLAETWPESITAVHFPKMEGTFTGSVLRTAFKTPFVRSN-- 73

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEV 131
                                  ++  L S  R      +  +  +G +++ DRY     
Sbjct: 74  ---------------------PRIMHLLFSANRWELMDFIGAELAKGKIVVCDRYF---- 108

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK---- 187
                 G  LA +       +     + +L Q      P   I L         RK    
Sbjct: 109 ------GSGLAYSMVKGLDQEWCEGPDRRLIQ------PDATIYLDAPLSALMKRKDWGA 156

Query: 188 -PDHQLAALQEKIAVTPQLTFNGAKILELDGR-HPADEILQASLRAI 232
               +    Q K+           +   +D     AD +       I
Sbjct: 157 DTVFETEEFQSKLIPIYDKLAREKRWTRIDADLLDADAVYTLVEGYI 203


>UniRef50_Q3AG12 Thymidylate kinase n=2 Tax=Bacteria RepID=KTHY_CARHZ
          Length = 203

 Score =  122 bits (306), Expect = 9e-27,   Method: Composition-based stats.
 Identities = 39/225 (17%), Positives = 73/225 (32%), Gaps = 41/225 (18%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I I G +GSGK+T    +   L  +              I   I++ P  G   G+ 
Sbjct: 3   GKFITIEGVEGSGKTTQIQYIARYLTEK-------------NIPHIITREPG-GTALGKK 48

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEVP 132
           +R    +           +    I L    RA     K++    +G  +I+DRY    + 
Sbjct: 49  IRELLLNP------SYPVVPEAEILLYLADRAQHVGEKIIPHLDKGVWVISDRYFDSTLA 102

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-KPDHQ 191
              +         G    + +L+       + +    P L + + +  +   +R K   +
Sbjct: 103 YQGY---------GRGFDLTLLKSFIAFATKGLI---PDLTVLIDLPPEVGLSRVKGRGE 150

Query: 192 LAALQEKIAVTPQLTFNGA-------KILELDGRHPADEILQASL 229
              L+ +     Q    G        +   +DGR   +EI     
Sbjct: 151 YDRLERETLEFHQRVREGFLQLARDQRFRVVDGRKKPEEIFWEIK 195


>UniRef50_Q8RDE6 Thymidylate kinase n=2 Tax=Thermoanaerobacteraceae RepID=KTHY_THETN
          Length = 208

 Score =  122 bits (306), Expect = 9e-27,   Method: Composition-based stats.
 Identities = 35/234 (14%), Positives = 69/234 (29%), Gaps = 44/234 (18%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I+  G DG GK+T    L   L        +       R+GE + ++ +        
Sbjct: 3   GKFISFEGIDGCGKTTQVKLLEEHLKKEGYDLLVLREPGGTRVGEKVREILLDRENL--- 59

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEVP 132
                                  + L +  RA     K+L    +G ++I DR+      
Sbjct: 60  -----------------IFPVTEMLLYASSRAQLVEEKILPALSKGQMVIVDRFIDSSYV 102

Query: 133 GFRF-DGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQ 191
              +  G  L K    N                     P + + + I  + A  R+   +
Sbjct: 103 YQGYARGLGLEKVKIVNEIA-------------TKGLFPDITVYIDITPEEAIKRRQGKK 149

Query: 192 LAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAAL 236
              L+ +     +    G          + + +DG      + +  ++A+   L
Sbjct: 150 ADRLEGEDYEFHKKVREGYLRLVKDFPERFILIDGMQEVLAVHKMVVKAVEEYL 203


>UniRef50_D2EGN9 dTMP kinase n=1 Tax=Candidatus Parvarchaeum acidiphilum ARMAN-4
           RepID=D2EGN9_9EURY
          Length = 200

 Score =  121 bits (304), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 37/232 (15%), Positives = 72/232 (31%), Gaps = 45/232 (19%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I I G D +GK T +  L   + ++     +    ++G +G              + 
Sbjct: 3   GKFIVIEGIDNAGKGTQSVLLAEHIRSKGFKVILTKEPTNGILG-----------GISKA 51

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQVEVP 132
             +K  ++  K           +  L    RA+    ++    + GF++I DRY    + 
Sbjct: 52  ALNKELNLSNKA----------LQLLFCADRAHHLETEIEPAMRDGFIVICDRYFFSTLA 101

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH-- 190
                          N   K LR   +          P L I L +D +T+ +R      
Sbjct: 102 ----------YGFASNINYKWLRSVNVSFR------KPDLGIYLDLDPKTSLSRAKKQVD 145

Query: 191 -----QLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
                       K+            I ++D +   + + Q   + I    +
Sbjct: 146 GLQLFDNLEKISKVRQAYLSIAKEFHIKKIDAKGDVEVVSQRINKIIDKFFN 197


>UniRef50_A9ETA2 Putative Thymidylate kinase n=1 Tax=Sorangium cellulosum 'So ce 56'
           RepID=A9ETA2_SORC5
          Length = 208

 Score =  121 bits (304), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 44/230 (19%), Positives = 77/230 (33%), Gaps = 36/230 (15%)

Query: 18  AIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLRSK 77
              G DG+G ST        L              + R    +++ P  G P G  LR  
Sbjct: 2   VFEGIDGAGTSTQAERFAAHL-------------RAARRMVHVTREPSAG-PVGALLRQV 47

Query: 78  AAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEVPGFRF 136
             H    P      I AL   L S  R      ++    + G+++I+DRY    +     
Sbjct: 48  LTHRISLPGARQAEIMAL---LFSADRLDHLGAEIEPLLRDGYVVISDRYDLSSLAYQ-- 102

Query: 137 DGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH-QLAAL 195
                    G    ++ +R+             P + + + +  + A  R+        L
Sbjct: 103 STTAGEDGAGSGAIVEWIRELNRHA------LRPDVTVVIDVAPEIAEKRRRGRGGAEEL 156

Query: 196 QEKIAVTPQLTFN---------GAKILELDGRHPADEILQASLRAIHAAL 236
            EK  +  +L            G +++ +DG    DE+ +A   A+ A +
Sbjct: 157 FEKTELQARLAEAYRRAEELVPGDRVIHIDGNGSVDEVARAITAALSAVV 206


>UniRef50_C8QYR9 Thymidylate kinase n=1 Tax=Desulfurivibrio alkaliphilus AHT2
           RepID=C8QYR9_9DELT
          Length = 222

 Score =  121 bits (304), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 36/234 (15%), Positives = 66/234 (28%), Gaps = 44/234 (18%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           +    +IA+ G DG+GKST    L   L        +    + G  G  + +L +  A  
Sbjct: 11  ARAGVLIALEGIDGTGKSTQQQLLAQRLRQLGLEVVVTREPTDGPYGRRLRELFLNRASL 70

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQV 129
                                     + L    R     K +    + G ++ITDRY   
Sbjct: 71  S---------------------PEEELQLFLADRREHVAKLIEPALKAGRVVITDRYYYS 109

Query: 130 EVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD 189
                   G   A     N                  +  P L++ L         R  +
Sbjct: 110 TAAYQGASGHDPAAILAINES---------------FAPRPDLVLLLEAPPAVGVRRVQE 154

Query: 190 HQLAALQEKIAVTPQLTFNG-------AKILELDGRHPADEILQASLRAIHAAL 236
            +  +L +           G         ++ ++     +++     +A+ A L
Sbjct: 155 GRGESLNDFEQEDYLRRVAGIFAGFSAPGLVRVNATGAIEQVQVEIWQAVEALL 208


>UniRef50_A3CPJ9 Thymidylate kinase n=29 Tax=Firmicutes RepID=KTHY_STRSV
          Length = 212

 Score =  121 bits (303), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 40/232 (17%), Positives = 78/232 (33%), Gaps = 42/232 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I++ G +G+GKS++  +L+  L                  G   ++ P      G  + 
Sbjct: 6   LISLEGPEGAGKSSVLEALLPFLQNYG-------------TGLITTREPG-----GVQIA 47

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                V  +PS    +    ++  ++  R +   ++L    QG L++ DR+    V    
Sbjct: 48  EAIREVILEPSHTAMDAKTELLLYIASRRQHLTERVLPALAQGKLVLMDRFIDSSVAYQG 107

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
           + G  L         I+ L Q             P L +   ID +   AR    +   +
Sbjct: 108 Y-GRGLDVA-----DIEWLNQF------ATDGLKPDLTLYFDIDVEEGLARIAKSESREV 155

Query: 196 QE------------KIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAA 235
                         +      L     + +++D   P D+++  SL  I   
Sbjct: 156 NRLDLEGLDLHQRVRQGYLAILDKEPERFVKVDASQPLDKVVADSLAIIQER 207


>UniRef50_B1ZU40 dTMP kinase n=3 Tax=Verrucomicrobia RepID=B1ZU40_OPITP
          Length = 216

 Score =  121 bits (303), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 40/242 (16%), Positives = 80/242 (33%), Gaps = 43/242 (17%)

Query: 8   IINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIG 67
           + +    ++I+  G +GSGKST  + L   L                      ++ P  G
Sbjct: 4   LKSKPTGKLISFEGSEGSGKSTQMSMLAARLQKDGRDVVT-------------TREPG-G 49

Query: 68  APFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRY 126
              G  +R+   H                + L +  RA   R+ +    Q+G ++++DRY
Sbjct: 50  TEIGEQVRNIIVHNSRGDEMC----AETELLLFAAARAQLVREVIAPAMQKGSIVLSDRY 105

Query: 127 PQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR 186
                    + G       G N     + Q        + + +P L I + +  +   AR
Sbjct: 106 LDSS---TVYQG------IGRNLAADPVAQINRFA---VGNVMPDLTIVIDVPAEVGLAR 153

Query: 187 ----------KPDHQLAALQEKIAVTPQLTFNG--AKILELDGRHPADEILQASLRAIHA 234
                     + + +     +K+     +   G   + + +DG    D + +    A+  
Sbjct: 154 IRQRASDLPDRMERENIDFYKKVRDGYLVLAKGMADRFVVIDGTQTQDVVSKKIFAAVKE 213

Query: 235 AL 236
            L
Sbjct: 214 RL 215


>UniRef50_B3DUA1 Thymidylate kinase n=8 Tax=Actinobacteridae RepID=KTHY_BIFLD
          Length = 206

 Score =  121 bits (303), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 36/233 (15%), Positives = 66/233 (28%), Gaps = 39/233 (16%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
               ++  G DG GK+T    L   L A+  T  +        +G+ I QL + G     
Sbjct: 2   SGLFVSFEGVDGVGKTTQVERLRAYLEAQGRTVVVTREPGGTALGKAIRQLLLHG----- 56

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEV 131
                                     L +  RA    + +    ++G ++ITDRY    +
Sbjct: 57  -----------VDGGAVDIAPRAEALLFAADRAQHVAETIRPALERGEVVITDRYLDSSL 105

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQ 191
                 G +L      +  +               + LP     L +D   +  R  +H 
Sbjct: 106 AYQA-GGRELTPEEIRSLSM-WATN----------NLLPDRTYLLDMDPALSHNRL-EHA 152

Query: 192 LAALQEKIAVTPQLTF---------NGAKILELDGRHPADEILQASLRAIHAA 235
              ++   +     T             +   +D     + +  A    I   
Sbjct: 153 EDRMESAGSDFQSRTRQAFLDLAAAEPNRFRVIDASQSIEAVWAAIESDIKEL 205


>UniRef50_Q0F3S1 Thymidylate kinase n=1 Tax=Mariprofundus ferrooxydans PV-1
           RepID=Q0F3S1_9PROT
          Length = 211

 Score =  121 bits (303), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 38/239 (15%), Positives = 68/239 (28%), Gaps = 45/239 (18%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            ++I   G DGSGKST      + L +              ++G  I QL + G      
Sbjct: 2   GKLITFEGGDGSGKSTQLRLTADWLTSIGKRIITTFEPGDTQLGAKIRQLLLSGE----- 56

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVP 132
                             +    + L    RA   R+ +    Q+G  ++ DRY    + 
Sbjct: 57  ---------------DVPVPECEMLLFLADRAQHVREVVQPALQRGDWVLCDRYSDSTLA 101

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP---- 188
              +               +ML   E  +        P L +   +    A  R      
Sbjct: 102 ---YQLAARKLGAADELLRQMLTFAECGVT-------PDLTLWFDLPVSAALERMRQRQQ 151

Query: 189 --------DHQLAALQEKI--AVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
                   D +  +  +++  A   Q      +++ +D       + Q     I    S
Sbjct: 152 AGEKSTRLDDEALSFHQRVTAAFASQAEAEPGRMMRVDAVGDIKSVEQQVHHIIRTRFS 210


>UniRef50_C5U715 dTMP kinase n=1 Tax=Methanocaldococcus infernus ME
           RepID=C5U715_9EURY
          Length = 184

 Score =  121 bits (302), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 38/223 (17%), Positives = 62/223 (27%), Gaps = 47/223 (21%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G DGSGK+TL+  L  EL+     E      + G IG  I      G        
Sbjct: 2   FIVFEGIDGSGKTTLSKMLAKELSGYWTCE-----PTDGEIGRLIRSYLSSG-------- 48

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                               +  L +  R    +++      G  +I DRY    +    
Sbjct: 49  --------------NIDNISLSLLFAADRVEHCKEIEKVLNSGRDVICDRYLYSSIAYQS 94

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---KPDHQL 192
             G +       N +                +  P L+  L +D   A  R   K   + 
Sbjct: 95  SLGVEENFLWEINKY----------------AIKPDLVFLLVVDVDEAMKRVKGKDIFEN 138

Query: 193 AALQEKIAVTPQLTFNGAKILELDGRH-PADEILQASLRAIHA 234
               EK+             + +D  +   +E        ++ 
Sbjct: 139 KNFLEKVQEKYLELAKRFNFIVIDTTNISIEEAYNKVRVKVYE 181


>UniRef50_Q1QX49 Thymidylate kinase n=11 Tax=Proteobacteria RepID=KTHY_CHRSD
          Length = 212

 Score =  120 bits (301), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 35/237 (14%), Positives = 74/237 (31%), Gaps = 40/237 (16%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
           TP R I + G +G GKST  A + + L+AR                   ++ P  G P  
Sbjct: 2   TPGRFITLEGGEGVGKSTNVAFVCDWLSARGIEVVR-------------TREPG-GTPRA 47

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEV 131
             +R        +    P + TA ++ + +    +   ++     +G  ++ DR+     
Sbjct: 48  EAIRELLLDPAPQE---PLDETAELLLMFAARAQHLAARIRPALARGAWVVCDRFTD--- 101

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQ 191
             F + G            ++ L Q             P L + L +  + A  R     
Sbjct: 102 ATFAYQGGGRGLDETRIATLEALVQ---------QGLQPDLTLLLDMPVEAAQRRVERRG 152

Query: 192 LAALQE-----------KIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
           +   +            + +   +      +   +D     + +  +    +   L+
Sbjct: 153 IERDRFERERGAFFNAVRESYLARAAQAPTRFAVIDADRSLEAVQASIAAHLTERLA 209


>UniRef50_B0MFL0 Putative uncharacterized protein n=5 Tax=Clostridiales
           RepID=B0MFL0_9FIRM
          Length = 216

 Score =  120 bits (301), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 39/233 (16%), Positives = 81/233 (34%), Gaps = 42/233 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G DG+GKST    L   L  +                  + + P  G      +R
Sbjct: 9   FITMEGPDGAGKSTQIDLLRVYLLQKGYDI-------------IVCREPG-GTVISEAIR 54

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
               +   K            + L +  RA    + +     QG ++I DR+ +      
Sbjct: 55  EVILNRDYKNMG-----HMTELLLYAAARAQLVEEVIQPALDQGKVVICDRFIESSA--- 106

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP------ 188
            + G            + ++ +        + + +P + + L +D +T   RK       
Sbjct: 107 VYQG------IARGLGVDLVYEVNRFA---VGNTMPDITLLLDVDAETGIGRKKQQAELD 157

Query: 189 --DHQLAALQEKIAVTPQL--TFNGAKILELDGRHPADEILQASLRAIHAALS 237
             + +      K+    +L    +  +++++DGR+  +EI +    A+  AL+
Sbjct: 158 RMESEKLEFHRKVVEGYRLLAERDKNRMVKIDGRNSIEEIHRQIKVAVDDALT 210


>UniRef50_A7BBF9 Putative uncharacterized protein n=3 Tax=Actinobacteridae
           RepID=A7BBF9_9ACTO
          Length = 270

 Score =  120 bits (301), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 35/235 (14%), Positives = 65/235 (27%), Gaps = 43/235 (18%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           +     I   G DGSGKST   S+ +   +R     +        +G  I +L   G   
Sbjct: 2   AARGVFITFEGGDGSGKSTQIQSVRDWFESRGREVIVTREPGGTELGTEIRRLVQNG--- 58

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQV 129
                            P          L +  RAY     +    ++G +++ DRY   
Sbjct: 59  -----------------PEDVDARTEALLYAADRAYHVATVIAPALERGAVVLADRYIDS 101

Query: 130 EVPGFRFDGPQLAKTT-GGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP 188
            +    + G   +              +             P L   L +  +    R+ 
Sbjct: 102 SLA---YQGAARSLGVDEIGSLSAWATR----------GLYPSLTFLLDLPPEVGARRRT 148

Query: 189 DH----QLAALQEKIAVTPQL----TFNGAKILELDGRHPADEILQASLRAIHAA 235
           D     +  ++     V  +          +I+ +D     DE+       +   
Sbjct: 149 DAPDRMERESMDFHERVRHEYLRLADAEPDRIVVIDAVGTVDEVFSEIRGVLVER 203


>UniRef50_A0ZZR0 Thymidylate kinase n=5 Tax=Actinobacteridae RepID=KTHY_BIFAA
          Length = 217

 Score =  120 bits (301), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 35/227 (15%), Positives = 66/227 (29%), Gaps = 35/227 (15%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
              I+  G DG GK+T    L   + ++     +        +G  I ++ + G   G  
Sbjct: 3   GTFISFEGVDGVGKTTQVERLRAYVESQGRECVVTREPGGTALGVAIRKMLLHGVDTGD- 61

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVP 132
                       +            L +  RA    + +L   Q+G ++ITDRY    + 
Sbjct: 62  -----------ENDCADIAPRTEALLFAADRAQHVAEVILPALQRGAVVITDRYLDSSLA 110

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQL 192
                G +L      N  +                 LP     L +D   + AR   H  
Sbjct: 111 YQA-GGRELTAAEIRNLSM-WATN----------GLLPERTYLLDMDPAQSHARL-QHAE 157

Query: 193 AALQE---------KIAVTPQLTFNGAKILELDGRHPADEILQASLR 230
             ++          ++A          +   +D     +++      
Sbjct: 158 DRMEAAGNDFQRRTRVAFLDLAEREPERFHVIDASQSIEDVWARIKA 204


>UniRef50_A5D690 Thymidylate kinase n=4 Tax=Clostridiales RepID=KTHY_PELTS
          Length = 216

 Score =  120 bits (300), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 37/235 (15%), Positives = 71/235 (30%), Gaps = 43/235 (18%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I   G DGSGK+T    L  +L +              R+GE I ++ +        
Sbjct: 3   GKFIVFEGVDGSGKTTQIKLLGEKLESMGCPVVYTREPGGTRVGERIREILL-------- 54

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVP 132
                             +      L +  RA    + +L   ++G +++ DR+    + 
Sbjct: 55  -----------NPLYGELVPWAEALLYAAARAQHVAQVILPALREGKVVLCDRFTDSSLA 103

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD--H 190
              +         G    I+ML Q         A  +P L++ L  D +    R      
Sbjct: 104 YQGY---------GRGVDIEMLEQVNRPA---AAGVVPDLVLVLDFDREGQTERMARSGR 151

Query: 191 QLAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAAL 236
               ++ +     +   +G          +   +D       +    L+A    L
Sbjct: 152 SADRIEREAQEFYRRVRSGYLALAARAPRRYRVIDASRAEKLVHLDVLKAAEEVL 206


>UniRef50_A8IRW9 Predicted protein (Fragment) n=1 Tax=Chlamydomonas reinhardtii
           RepID=A8IRW9_CHLRE
          Length = 214

 Score =  119 bits (299), Expect = 5e-26,   Method: Composition-based stats.
 Identities = 36/226 (15%), Positives = 71/226 (31%), Gaps = 36/226 (15%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
             +I   G D  GK+T  + +V  L ++     ++          +  +   IGA    Y
Sbjct: 9   GALIVFEGGDRCGKTTQCSKMVERLKSQGVDAVMW---------RFPDRSTSIGAAINAY 59

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           L +++               A++  L    R  K  +ML     G  L+ DRY    V  
Sbjct: 60  LSNQS-----------QLDDAVIHMLFVANRLEKRDEMLRLLAGGTTLVLDRYSYSGVAY 108

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK--PDHQ 191
               G         +  I   +  E+ L          L++ + +  +   AR    + +
Sbjct: 109 TAAKGV-------PHLSIDYCKSLEVVL------PAADLVVHMSMSAEATAARGGYGEER 155

Query: 192 LAALQEKIAVTPQLT-FNGAKILELDGRHPADEILQASLRAIHAAL 236
              ++ +  V          +   +D     D I +     +   +
Sbjct: 156 YEKVEFQARVMEAFGQLRDERWAAIDAAGTIDAIHEQVAAVVEPVV 201


>UniRef50_Q0C176 Thymidylate kinase n=1 Tax=Hyphomonas neptunium ATCC 15444
           RepID=Q0C176_HYPNA
          Length = 219

 Score =  119 bits (299), Expect = 6e-26,   Method: Composition-based stats.
 Identities = 41/240 (17%), Positives = 83/240 (34%), Gaps = 40/240 (16%)

Query: 8   IINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIG 67
           + ++     I + G +G+GKSTL  +L  +L A               IG  +++ P  G
Sbjct: 1   MTDTAAGHFITLEGGEGTGKSTLAKALARKLEAHG-------------IGVVVTREPG-G 46

Query: 68  APFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYP 127
            P     R    H  E  +  P +   LV    +  R +  + +     +G  +I DR+ 
Sbjct: 47  TPLAEAARQLLLHPPEGEAWSPLSEALLVN---AARRDHLEKLIRPALARGDWVICDRFA 103

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK 187
                       ++ ++  G   +  L   E    + +   +P + + L +    A  R+
Sbjct: 104 DS---------TRVYQSIEGGVDVSALLSIER---EVLGDTVPSMTLILDVSLDVASKRR 151

Query: 188 PDH--QLAALQEKIAVTPQLTF---------NGAKILELDGRHPADEILQASLRAIHAAL 236
                 L   + +     +              A+   +D     D++L A+ + +   L
Sbjct: 152 TARAGALDTFERRPKAFHEAVRAAFQDIARSEPARCRLIDTDVTPDQVLDAAWKQVATLL 211


>UniRef50_A6LPM3 Thymidylate kinase n=175 Tax=Firmicutes RepID=KTHY_CLOB8
          Length = 213

 Score =  119 bits (298), Expect = 8e-26,   Method: Composition-based stats.
 Identities = 28/235 (11%), Positives = 75/235 (31%), Gaps = 42/235 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
              I   G +G+GK+T   ++ + +     TE+ +    +   G         G      
Sbjct: 4   GLFIVFEGGEGTGKTTAIDAIYDWI-----TENNFECIKTREPG---------GIKISEQ 49

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           +R        K            +   +  R +   K++    QG +++ DR+    +  
Sbjct: 50  IRQVILSKDNKEMDAKTE----ALLYAAARRQHLVEKVIPALNQGVIVLCDRFIDSSLAY 105

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLA 193
             +           N  I+ +          +  Y+P + +   +D +   AR  ++   
Sbjct: 106 QGY---------ARNLGIEEVLSINKFA---IGEYMPDISVLFDLDPKIGLARIANNDCR 153

Query: 194 ALQE----------KIAVTPQLTF--NGAKILELDGRHPADEILQASLRAIHAAL 236
            +            ++     + +  N  +I+++D  +  + ++      +   +
Sbjct: 154 EVNRLDIEKLEFHERVREGYDIVYKNNNHRIVKIDANNTKENVINQIKNILRPKI 208


>UniRef50_Q28SW8 Thymidylate kinase n=39 Tax=Rhodobacterales RepID=KTHY_JANSC
          Length = 208

 Score =  119 bits (298), Expect = 8e-26,   Method: Composition-based stats.
 Identities = 44/236 (18%), Positives = 71/236 (30%), Gaps = 42/236 (17%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
           P   I++ G DGSGKST TA LV+ L  R                E I +L V G P   
Sbjct: 2   PPLFISLEGIDGSGKSTQTARLVDWLRVRGRDPLQTREPGGSEGAEEIRRLLVEGDP--- 58

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVP 132
                             +    ++   +  R +  R +      G  ++TDR+      
Sbjct: 59  ---------------DRWSAETEILLFTAARRDHLERTIRPALASGRDVVTDRFADST-- 101

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK--PDH 190
              + G               LR    +++       P L + L +D + A +R    D 
Sbjct: 102 -RVYQGATRGA----------LRGLVDRIHAEAIEAEPDLTLILDMDPELALSRGLARDS 150

Query: 191 QLAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAALS 237
                ++      Q    G          +   +D     D I       +   L+
Sbjct: 151 GEDRFEDFGLPFQQKLRAGFQALAREYPDRCHIVDASADPDAIAHTIQTIVGQRLA 206


>UniRef50_A6C348 Thymidylate kinase n=1 Tax=Planctomyces maris DSM 8797
           RepID=A6C348_9PLAN
          Length = 222

 Score =  119 bits (297), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 45/241 (18%), Positives = 76/241 (31%), Gaps = 42/241 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IAI G DGSGK T  A L     A            +  IG       + G   G +L 
Sbjct: 4   IIAIEGIDGSGKGTQAARLHARCQAEG--------IKTSLIGFPRYDQTLFGKSIGDFLN 55

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
            +   + E           L   L +  R      +L   +   ++I DRY    V    
Sbjct: 56  GRFGELDEVN-------PFLASLLYAGDRFESRSHILNTIETSDVVIFDRYIPSNVA--- 105

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
             G +L+     + +I+ + Q E  +Y+        L I L +    A     + Q  + 
Sbjct: 106 HQGAKLS-GAERSEFIEWIEQIEYAIYK---MPRLNLAILLDLPADYAQKLIAEKQARSY 161

Query: 196 QEKIAVTPQLT--------------------FNGAKILELDGRHPADEILQASLRAIHAA 235
            EK+A   +                      +   + L+ +     +EI       +   
Sbjct: 162 TEKVADLQEADQTYLANVREVYLQLAEENQHWQKIQCLQKETLRSIEEISDEIWSYVSKL 221

Query: 236 L 236
           +
Sbjct: 222 I 222


>UniRef50_Q6CW62 KLLA0B06556p n=1 Tax=Kluyveromyces lactis RepID=Q6CW62_KLULA
          Length = 208

 Score =  118 bits (296), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 40/232 (17%), Positives = 73/232 (31%), Gaps = 44/232 (18%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            ++I I G D +GKST   ++VN L                 + ++  +   IG    +Y
Sbjct: 4   GKLILIEGLDRTGKSTQCENVVNALGN------------DAVLIKFPDRTTKIGQLINQY 51

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           L  K   +              +  L S  R     ++    + G  ++ DRY    V  
Sbjct: 52  LTDKDFEL----------PAQSIHLLFSANRWELKEEIHSMLKAGKHVVLDRYVYSGVAY 101

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRL----GIDEQTAFARKPD 189
               G Q          I      +  L        P L +       + ++  F  +  
Sbjct: 102 SAAKGIQ-------GMDISWCFNPDKGL------LKPDLTLFFSNSSNMRDREGFG-EER 147

Query: 190 HQLAALQEKIAVTPQLTFNGAKI---LELD-GRHPADEILQASLRAIHAALS 237
           ++    Q ++  T    F+  K    + +D      DE+       IH  ++
Sbjct: 148 YEKVEFQRQVRDTFFNVFDQIKDSNRIVIDVSDKSIDEVFSEIKPLIHDVIN 199


>UniRef50_A5WBP5 Thymidylate kinase n=4 Tax=Moraxellaceae RepID=KTHY_PSYWF
          Length = 208

 Score =  118 bits (296), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 31/233 (13%), Positives = 71/233 (30%), Gaps = 38/233 (16%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + ++  G +G GK+T    L   L A+                   ++ P  G+PF   
Sbjct: 4   GKFVSFEGTEGVGKTTAINGLCERLQAQGIEYVR-------------TREPG-GSPFAEQ 49

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           LR               N    ++ + +    +  + ++     G  +I DR+    V  
Sbjct: 50  LRELLLDTR-----TQINDDTELLLMFAARSDHLAQVIMPALSAGKWVICDRFIDSTVAY 104

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQ-L 192
             + G              ML + E  +  ++    P + + L +       R       
Sbjct: 105 QGY-GRGFGNA-------DMLHKIEALIAGFVPRL-PDITLWLDLPVAEGMQRAGKRSVA 155

Query: 193 AALQEKIAVTPQLTFNGAK---------ILELDGRHPADEILQASLRAIHAAL 236
              +++        + G +         I  +D +   +++     +++   L
Sbjct: 156 DRFEQQQLDFFDRVYQGFEAQQQAQPQRIQRIDAQGEVEQVADRIWQSVSQQL 208


>UniRef50_Q91FS1 Putative thymidylate kinase 251L n=1 Tax=Invertebrate iridescent
           virus 6 RepID=KTHY_IIV6
          Length = 213

 Score =  118 bits (296), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 40/239 (16%), Positives = 71/239 (29%), Gaps = 45/239 (18%)

Query: 6   MSIINSTP-----VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWI 60
           MS+  S P       +I   GCD +GKST    L  EL  +     +           + 
Sbjct: 1   MSLKQSFPLLETRGLLIVFEGCDKTGKSTQCKLLFEELKQKNIEVRMI---------NFP 51

Query: 61  SQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFL 120
           ++    G    +YL+ K     E            +  L S  R      +      G  
Sbjct: 52  NRTTQTGKLIDQYLKGKIYLSDED-----------IHILFSKNRWEIIDTIKTNILNGIT 100

Query: 121 LITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDE 180
           +I DRY              +A +       +  +Q E  L        P ++I L    
Sbjct: 101 VIIDRYSYS----------GIAFSVAKGLDFQWCKQTENGL------LKPDIIIYLTGQT 144

Query: 181 QTAFARK----PDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAA 235
           +   +R       ++   +Q+K+    +         +++       I +     I   
Sbjct: 145 KNMASRNGYGSEIYERIEIQDKVKKCYEKMIEIPLWNKINADQDVLIIKKQIETIIQKF 203


>UniRef50_D1A586 Thymidylate kinase n=1 Tax=Thermomonospora curvata DSM 43183
           RepID=D1A586_THECD
          Length = 671

 Score =  118 bits (296), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 32/232 (13%), Positives = 64/232 (27%), Gaps = 40/232 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
              IA  G +G+GK+T        L              + ++G  +  + +        
Sbjct: 451 GVFIAFEGGEGAGKTTQARLTAIWLRDHGYDVVTTNEPGATKVGMRLRAILL-------- 502

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVP 132
                           G        L +  RA      +    ++G ++++DRY    + 
Sbjct: 503 -----------DKETTGLSARAETLLYAADRANHVANVIKPALERGAIVVSDRYVDSSLA 551

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF-------A 185
              +         G    ++ + +             P L + L +  QT          
Sbjct: 552 YQGY---------GRELPVEEIAEVNRWATD---GLQPDLTVLLDLPPQTGLGRFASPAD 599

Query: 186 RKPDHQLAALQEKIAVTPQLTFNGA-KILELDGRHPADEILQASLRAIHAAL 236
           R     L   +       +L      + L LD   P +E+ +     +   L
Sbjct: 600 RMESEPLDFHERVRRGFRKLAEADPDRYLVLDATRPQEELSRQIRDRLRQIL 651


>UniRef50_B9XNP9 dTMP kinase n=1 Tax=bacterium Ellin514 RepID=B9XNP9_9BACT
          Length = 213

 Score =  118 bits (295), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 37/239 (15%), Positives = 72/239 (30%), Gaps = 46/239 (19%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
             +I+  G +G GKST  + L   L A                   + + P  G P G  
Sbjct: 4   GLLISFEGTEGCGKSTQISLLTERLRALGHVIR-------------MVREPG-GTPIGEE 49

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKM-LCKSQQGFLLITDRYPQVEVP 132
           +R    H            +   + L++  RA   R++     + G +++ DRY      
Sbjct: 50  IRYTLKH----SVKNHAMTSEAELLLMNASRAQLVREVLRPALEAGEIIVCDRYYDSTTA 105

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQ- 191
              +         G    +K+++     +   +    P L + L +  + + AR    Q 
Sbjct: 106 YQGY---------GRGLDLKLVQ---AVIDFAVGDTRPDLTLLLRVPPEVSAARLASRQA 153

Query: 192 -----LAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAAL 236
                   ++E           G          +I  +D       +  +    +   L
Sbjct: 154 TLPFIRDRIEEADQSFFNRVSQGYEALATAHPERIQTIDASSSVQNVSDSIWSRVKPLL 212


>UniRef50_C5RNT5 dTMP kinase n=2 Tax=Clostridia RepID=C5RNT5_CLOCL
          Length = 212

 Score =  118 bits (294), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 36/235 (15%), Positives = 67/235 (28%), Gaps = 41/235 (17%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           +    +I I G DGSGKST    L      R                   ++ P  G   
Sbjct: 7   NNRGYLITIEGPDGSGKSTQIELLKKYFNDRGYEVVT-------------TREPG-GTKI 52

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKM-LCKSQQGFLLITDRYPQV 129
              +R        +              L +  RA    ++      +G +++ DR+   
Sbjct: 53  SEKIRELILDNDNEEMNGICE-----ALLYAASRAQLVEQVLKPAIYEGKIVLCDRFVHS 107

Query: 130 EVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD 189
            +    +              +  +          +      L I + I  +    RK  
Sbjct: 108 SLVYQGY---------ARELGVNQVLNINEFA---LNGLKADLTIMIDIPYELGIERKRK 155

Query: 190 H-QLAALQEKIAVTPQLTFNGAK--------ILELDGRHPADEILQASLRAIHAA 235
             +L  L+          FNG +        ++ +DG    +EI +  ++ I   
Sbjct: 156 QKKLDRLENGGDEFHNKVFNGYQQIVKTMKNVVIIDGTKAVEEIHKDIVKTIAEL 210


>UniRef50_A8PE11 Thymidylate kinase, putative n=1 Tax=Brugia malayi
           RepID=A8PE11_BRUMA
          Length = 213

 Score =  118 bits (294), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 35/233 (15%), Positives = 65/233 (27%), Gaps = 39/233 (16%)

Query: 10  NSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAP 69
           +      I   GCD +GKS  +  LV  + A               +  +  +   +G  
Sbjct: 3   SRIRGAFIVFEGCDRAGKSLQSRKLVERIKAAGGDV---------DLISFPDRSSDLGKF 53

Query: 70  FGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQV 129
             RYL+ +                     + +  R      M+ K  +G  L+ DRY   
Sbjct: 54  IDRYLKKEVE-----------MDPKEAHLVFAANRQALMPLMMKKLLKGTHLVVDRYAYS 102

Query: 130 EVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK-- 187
            +      G         N  ++  +  +      M    P  +I   +  + A  R   
Sbjct: 103 GIAYTLAKGAD-------NITMEWAKLAD------MGELRPDCVIYFNLSFEEAQKRSGF 149

Query: 188 --PDHQLAALQEKIAVT--PQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                     Q K++         +      +D     +EI +     +   L
Sbjct: 150 GDERFDFGNFQGKVSKVMEQLADEDRDLWKVVDASLTVEEISENVWNLVAPIL 202


>UniRef50_A9MB09 Thymidylate kinase n=42 Tax=Alphaproteobacteria RepID=KTHY_BRUC2
          Length = 214

 Score =  118 bits (294), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 37/239 (15%), Positives = 68/239 (28%), Gaps = 45/239 (18%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
               I   G +G+GKST  A L + L                     I++ P  G+P   
Sbjct: 2   SGLFITFEGGEGAGKSTQIALLASHLRNHG-------------FDPVITREPG-GSPGAE 47

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEV 131
            +R                  A+   L +  RA    + +     +G +++ DR+     
Sbjct: 48  AIRHVIL-----SGNAETYGPAMEALLFAAARADHVDQLIRPALAEGRIVLCDRFIDS-- 100

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF----ARK 187
            G  + G        GN     +   E      +   +P L + L I  +        R+
Sbjct: 101 -GRAYQGVT------GNLDATYMAAIERIA---IDGAMPDLTLVLDICAERGLSRAGKRR 150

Query: 188 PDHQLAALQ---------EKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
                   +          + A         A+   +D     ++I       +   L+
Sbjct: 151 GSDTADRFEKEDIAVHEARRQAFLEIARQEPARCKVIDADRSQEKIADEIRSVVDTILT 209


>UniRef50_O67099 Thymidylate kinase n=2 Tax=Aquificaceae RepID=KTHY_AQUAE
          Length = 195

 Score =  118 bits (294), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 37/226 (16%), Positives = 76/226 (33%), Gaps = 39/226 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA  G DGSGK+T    L   L  +     +Y      ++GE + ++ +      R   
Sbjct: 2   LIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDER--- 58

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEVPGF 134
                                + L    R+     K++   ++  ++I DR+    +   
Sbjct: 59  -------------------TELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQ 99

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---KPDHQ 191
            +         G    ++ ++       + +    P + + L I    A  R   K   +
Sbjct: 100 GY---------GKGLDVEFIKNLNEFATRGV---KPDITLLLDIPVDIALRRLKEKNRFE 147

Query: 192 LAALQEKIAV-TPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                EK+     +L      ++ +D     +E+ +  LRA+   L
Sbjct: 148 NKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVL 193


>UniRef50_A4XHH4 Thymidylate kinase n=1 Tax=Caldicellulosiruptor saccharolyticus DSM
           8903 RepID=KTHY_CALS8
          Length = 206

 Score =  118 bits (294), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 34/233 (14%), Positives = 68/233 (29%), Gaps = 42/233 (18%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I   G DGSGKST    +   L  +              +G  I +L +        
Sbjct: 3   GKFIVFEGNDGSGKSTQILKVEKYLKEKGYKVVTTREPGGTEVGFRIRKLLL-------- 54

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKML-CKSQQGFLLITDRYPQVEVP 132
                                    LL+  R    + +L    + G++++ DRY    + 
Sbjct: 55  ------------DPAYKMDGLTEALLLAADRNEHVKNVLIPALEDGYVVVCDRYILSSI- 101

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR------ 186
              + G            +  + +             P L I L +  + A  R      
Sbjct: 102 --VYQGIVRGVGVENIIKLNSIFE---------EKIKPDLYIILTLSPEIALQRLKMAGK 150

Query: 187 --KPDHQLAALQEKIAV-TPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
             K D +      K+     +++    K + ++     +++ +   + I   L
Sbjct: 151 NDKLDTENFDFHRKVYNGFKEVSKMFKKCVNIEAEGTVEDVFEKVRKVIDDLL 203


>UniRef50_Q1PY20 Similar to thymidylate kinase n=1 Tax=Candidatus Kuenenia
           stuttgartiensis RepID=Q1PY20_9BACT
          Length = 234

 Score =  117 bits (293), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 43/257 (16%), Positives = 76/257 (29%), Gaps = 45/257 (17%)

Query: 1   MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWI 60
           M Q    I+     ++I I G DGSGK+  T  L   L               G+     
Sbjct: 1   MAQYGECIMQ---GKLIVITGIDGSGKTVQTKLLYERLLKEGYPVATIDFPQYGK----- 52

Query: 61  SQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFL 120
                      +YLR                   L   L +  R  K  ++      G +
Sbjct: 53  ---TFFAEMVAKYLRGSF-------GAADAVSPYLASILYAGDRFEKKDQIQTWIDAGKI 102

Query: 121 LITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDE 180
           +I++RY    +      G ++  +     + + L Q E  ++       P L I L +  
Sbjct: 103 IISNRYVCDNMA---HQGGKIKNSEERAQFFQWLDQLEHTVF---GIPRPHLSILLYVPA 156

Query: 181 QTAF--------------ARKPDHQLA--ALQEKIAVTPQLTFNGAKILELDGRH----- 219
           + A+              A+K  H+     ++       ++         +D        
Sbjct: 157 EIAYFLVEKKGQREYLAGAKKDIHEEDMHHMKSAQETFIEIAKGKPNWKTVDCTKNNTLL 216

Query: 220 PADEILQASLRAIHAAL 236
           P   I     +A+   L
Sbjct: 217 PEHVIADTIWQAVAKIL 233


>UniRef50_Q9RY40 Thymidylate kinase n=14 Tax=Bacteria RepID=KTHY_DEIRA
          Length = 206

 Score =  117 bits (293), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 43/235 (18%), Positives = 72/235 (30%), Gaps = 43/235 (18%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
           +    I + G +G+GK+T  A L   L A                   +++ P  G P G
Sbjct: 2   SQGLFITLEGPEGAGKTTQLARLEARLRAAGHAV-------------TVTREPG-GTPLG 47

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKM-LCKSQQGFLLITDRYPQVE 130
             +R        +              L S  RA   R++     ++G  ++ DRY    
Sbjct: 48  TRVREVVLDPAVE------IEPLGEFLLYSASRAQLVREVLRPALERGETVLCDRYADSS 101

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH 190
           +    + G            + +LRQ      +      P L + L +D      R    
Sbjct: 102 LA---YQGAG------RGLSLPLLRQITA---EVTGGLTPGLTVLLDLDPALGLQRAARR 149

Query: 191 -QLAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAA 235
            Q   L++      +    G          + L LD   P DE+      A+   
Sbjct: 150 GQPDRLEQADLTFHRRVRQGFLDLAHAEPQRFLVLDATRPEDELEAEIWAAVSER 204


>UniRef50_A5G4M6 Thymidylate synthase / thymidylate kinase n=3 Tax=Bacteria
           RepID=A5G4M6_GEOUR
          Length = 228

 Score =  117 bits (293), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 41/249 (16%), Positives = 67/249 (26%), Gaps = 58/249 (23%)

Query: 7   SIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVI 66
           S+    P ++IA+ G DGSGKST    L   L  R    +                    
Sbjct: 4   SLTTELPGKLIAVEGLDGSGKSTQLYLLKRWLELRGLKVYFT------------------ 45

Query: 67  GAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRY 126
                  +  KA    +K         +L+       R    R++L   + G+L++ DRY
Sbjct: 46  -EWNSSVIVKKATSKGKKRQLLTPTTFSLIHSADLADRYE--RQILPLLKAGYLVLCDRY 102

Query: 127 PQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR 186
                          A+          LR        +  +  P L +        A +R
Sbjct: 103 VY----------TAFARDAVRGCSRTWLRNL------YGFARHPDLTLFFDTPLSVALSR 146

Query: 187 K---------------------PDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEIL 225
                                 P       QE+I        +    + +DG    +E  
Sbjct: 147 ILSGRPQLKYHEAGMDLGLANDPYQSFRLFQERIYNEYLGMRDEFSFVTIDGSVSIEEQQ 206

Query: 226 QASLRAIHA 234
                 +  
Sbjct: 207 IKVREIVGQ 215


>UniRef50_A9BG59 Thymidylate kinase n=11 Tax=Bacteria RepID=A9BG59_PETMO
          Length = 232

 Score =  117 bits (292), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 31/240 (12%), Positives = 64/240 (26%), Gaps = 43/240 (17%)

Query: 14  VRVIAIV-GCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
             +I I  G D SGK+T    L   L       +     +       + ++ + G     
Sbjct: 4   GMLIVIESGTDASGKATQAEILSQRLKDEKIKAYKVEFPNYKSDSSALIKMYLKG----- 58

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEV 131
                     E    P            +  R   + +++    + G +LI+DRY     
Sbjct: 59  ----------EFGENPEAINPYAASTFFAVDRFATYQKELKPLYESGGILISDRYTTSN- 107

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF----ARK 187
               +   +    +  + +++ L   E   +       P  +I L I  + +      RK
Sbjct: 108 --MIYQSSKFENQSEKDEFLEWLWDLE---FNKFNLPKPNYVIFLDIPPKISIELLRKRK 162

Query: 188 PD----------HQLAALQEKIAVTPQLTFNGAKILELD------GRHPADEILQASLRA 231
                        +      K     +          ++           +EI +     
Sbjct: 163 EKIIDLTGKDIHEKNIEYINKTYENAKYIAQKYNWTIINCLKENEELKSIEEIHEEIYSI 222


>UniRef50_D1WS25 Thymidylate kinase n=10 Tax=Actinomycetales RepID=D1WS25_9ACTO
          Length = 1084

 Score =  117 bits (292), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 42/236 (17%), Positives = 77/236 (32%), Gaps = 42/236 (17%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           +     +A+ G DG+GKST   +L + + ++                  +++ P    P 
Sbjct: 504 AATGFFLALEGGDGAGKSTQVEALADWIRSKGHEVV-------------VTREPGA-TPI 549

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQV 129
           G+ LRS    V        G        L +  RA      +    ++G ++I+DRY   
Sbjct: 550 GKRLRSILLDVSS-----AGLSNRAEALLYAADRAEHVDSVVRPALERGAIVISDRYIDS 604

Query: 130 EVPGFRFDGPQLA-KTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-- 186
            V    + G       T      +                +P L + L +D  TA  R  
Sbjct: 605 SVA---YQGAGRDLAPTEIARISRWATS----------GLVPHLTVLLDVDPATARERFT 651

Query: 187 ----KPDHQLAALQEKIAV--TPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
               + + + AA  E++          +  + L +D     + I       +   L
Sbjct: 652 EAPDRLESEPAAFHERVRSGFLTLAAADPTRYLVVDAGQEPESITTVVRHRLDQLL 707


>UniRef50_A2CD19 Thymidylate kinase n=16 Tax=Cyanobacteria RepID=KTHY_PROM3
          Length = 216

 Score =  116 bits (291), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 35/234 (14%), Positives = 70/234 (29%), Gaps = 39/234 (16%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARM---PTEHIYLGQSSGRIGEWISQLPVIGAP 69
             R++ + G DG GK+T    L N L           ++L +  G            G  
Sbjct: 2   SGRLLVLEGIDGCGKTTQLRHLANWLPRSGLMPEGARLHLTREPG------------GTA 49

Query: 70  FGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQ 128
            G  LR     +   P           + L +  RA    + +    +QG  +++DR+  
Sbjct: 50  LGMALR----KLVLHPPGDASPEPLAELLLYAADRAQHVAQLIRPALEQGHWVLSDRFSG 105

Query: 129 VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP 188
             +    +         G    + +++Q E       A  +P L   L +  + +  R+ 
Sbjct: 106 STLAYQGY---------GRELDLDLIQQLEQIA---TAGLVPDLTFWLELSVEESLVRRD 153

Query: 189 DHQLAALQEKIAVTPQLTFNGA-------KILELDGRHPADEILQASLRAIHAA 235
                 ++ +          G          + L      + +  A    +   
Sbjct: 154 ARSNDRIEAEGVDFLTRVATGFAVLARERSWVPLQADQQVESVSSALESQLKHH 207


>UniRef50_Q581B1 Thymidylate kinase, putative n=3 Tax=Trypanosoma brucei
           RepID=Q581B1_9TRYP
          Length = 345

 Score =  116 bits (291), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 41/245 (16%), Positives = 81/245 (33%), Gaps = 41/245 (16%)

Query: 10  NSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAP 69
           N++   VI   G DG+GK+T T  +   L                         P     
Sbjct: 124 NNSESAVIVFEGGDGAGKATQTEYMRKRLDKEGKAH-------------ASLDFPSDKHR 170

Query: 70  FGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQV 129
           +G+ +R     +  +          L   L S  R     ++      G  ++ DRY   
Sbjct: 171 YGKLIRKV---LSGERGALHDLDPKLFSLLFSLNRFDTLPELRYWLTHGKKILLDRYYTS 227

Query: 130 EVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF-ARKP 188
               F     +L ++   + +I+ L Q EL   +W+    P + + L +    A  A + 
Sbjct: 228 N---FGHQASKLEESERSD-FIRHLEQLEL---EWLKLPPPDVALYLDLPPAAALVAMQR 280

Query: 189 DHQLAALQ--------EKIAVTPQLTF---NGAKILELD------GRHPADEILQASLRA 231
           D +  +L          K  V     +   N    ++++       R+  +++ +    A
Sbjct: 281 DEKRESLDIHETAGLSYKENVRQTYVWCCQNQRNWVQIECCNDEGERYSREKVHEMIYNA 340

Query: 232 IHAAL 236
           +   +
Sbjct: 341 VAKHI 345


>UniRef50_C0QI33 Thymidylate kinase n=1 Tax=Desulfobacterium autotrophicum HRM2
           RepID=KTHY_DESAH
          Length = 227

 Score =  116 bits (290), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 34/239 (14%), Positives = 70/239 (29%), Gaps = 49/239 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G +GSGK+T    LV+ L        +     +  IG+ I  + +          
Sbjct: 2   FITLEGIEGSGKTTQIKPLVDCLGQNGYEAVVTREPGATVIGKKIRAILL---------- 51

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
                         G      ++L    RA    + ++     G  ++ DR+        
Sbjct: 52  ---------DPGNSGMSDLCELFLYGADRAQHLSEVIIPALGAGKTVVCDRFTD---ATT 99

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-------- 186
            + G     +             ++     +    P L I   +D +T  AR        
Sbjct: 100 VYQGAARGISKEL---------IDIIHSVVVKDLCPDLTILFDLDPETGLARTVKALTDG 150

Query: 187 -------KPDHQLAALQEKIA--VTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                  + + +     E++             + L +D R   +++    +  I+  L
Sbjct: 151 ERTLDESRFERETLEFHERVRQGYLALAAAEQDRFLVVDARGTQEQVFTEIVSGINRRL 209


>UniRef50_B6KVJ7 Thymidylate kinase, putative n=3 Tax=Toxoplasma gondii
           RepID=B6KVJ7_TOXGO
          Length = 273

 Score =  116 bits (290), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 38/264 (14%), Positives = 70/264 (26%), Gaps = 50/264 (18%)

Query: 6   MSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPV 65
           M+        ++   G D SGKST        L                 +  +  +   
Sbjct: 1   MAAFTPKRGCLVVFEGIDRSGKSTQARLAYERLTKEGHA---------AELIRFPDRTTP 51

Query: 66  IGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDR 125
           IG    R+L + +     +    P     L   L +  R     ++L    +G  ++ DR
Sbjct: 52  IGQVLDRFLANASWSSDGQHPQVP--PPQLTHLLFAANRWEAQARILRALGEGRTVLVDR 109

Query: 126 YPQVEVPGFRFDGPQLAKTTGGNG----------------------------WIKMLRQR 157
           Y    +       P +A+T                                      R+ 
Sbjct: 110 YSFSGIAYTVGAAPSVAETEATRLRREAEASGDVEKTAEAVAASTAATGAPVDATFCRES 169

Query: 158 ELKLYQWMASYLPVLLIRLGIDEQTAFARK--PDHQLAAL--QEKIAVTPQLTFNGAKIL 213
           E  L        P  +  L +  Q    R    D     L  QE++    +   N     
Sbjct: 170 ERGL------LAPDAVFFLDVAPQETQKRGGYGDEVYEKLATQERVYQVYRQFDNLPYWR 223

Query: 214 ELDGRH-PADEILQASLRAIHAAL 236
            +       +E+ +     + + +
Sbjct: 224 RIAASSLSIEELHEKLFEQLKSVI 247


>UniRef50_D1PL57 dTMP kinase n=1 Tax=Subdoligranulum variabile DSM 15176
           RepID=D1PL57_9FIRM
          Length = 223

 Score =  116 bits (290), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 36/244 (14%), Positives = 70/244 (28%), Gaps = 43/244 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            ++I   G DGSGK T TA    +L A           +       + ++ + G    + 
Sbjct: 2   GKLIIFEGLDGSGKGTQTALTAQKLKAHGVDLRQITFPNYESDSSALVKMYLSGQFGDK- 60

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVP 132
                         P            +  R   ++       + G L+++DRY      
Sbjct: 61  --------------PDDVNAYAASSFYAVDRFASYKTDWGDFYRAGGLILSDRYTTSNA- 105

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA------- 185
                  +L        ++  L   E   Y+ +    P  ++ L +D + +         
Sbjct: 106 --VHQCAKLPPMHWDG-FLNWLFDFE---YKKIGIPAPDAVVYLAVDPEVSQKLMDQRYH 159

Query: 186 --------RKPDHQLAALQEKIAVTPQLTFNGAKIL-----ELDGRHPADEILQASLRAI 232
                   ++ D +  A     A      F   +I      ++      ++I    L  I
Sbjct: 160 GDESKKDIQEKDREYIARSRAAAEYCAKMFGWYRIECTEGQDVKTIRSVEDINAEILAKI 219

Query: 233 HAAL 236
              L
Sbjct: 220 QPIL 223


>UniRef50_C1ZEK7 Thymidylate kinase n=1 Tax=Planctomyces limnophilus DSM 3776
           RepID=C1ZEK7_PLALI
          Length = 236

 Score =  116 bits (290), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 36/248 (14%), Positives = 69/248 (27%), Gaps = 42/248 (16%)

Query: 10  NSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAP 69
           + +   +I I G DG+GK T T  L   L +                     +    G  
Sbjct: 8   HPSSGLLIVIEGIDGAGKGTQTKLLHERLKSTSRDVFTLSFPRY--------ESTFFGQR 59

Query: 70  FGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQV 129
              +L  +   +             L   L +  R      +     +G +++ DRY   
Sbjct: 60  VADFLNGRFGTL-------EQVHPFLAAMLYAGDRFESRDLLQSALNEGKIVLCDRYIPS 112

Query: 130 EVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD 189
            +          A+        + +   E  LYQ      P L++ L    +TA      
Sbjct: 113 NLAHQ----LTKAQPELRAEMQQWIEHVEYHLYQ---MPRPDLVVLLDTTAETATTLIDR 165

Query: 190 HQLAALQEKIAVTPQLTFNGAKILELD-----GRHPA---------------DEILQASL 229
            Q        A   +   +  + + ++       +P                 EI +   
Sbjct: 166 KQARDYTTSKADLHEADQHYLERVLIEYRNLAANNPLWHVVPCLQNSILRSQTEIAEEIY 225

Query: 230 RAIHAALS 237
             + + +S
Sbjct: 226 TFVESFIS 233


>UniRef50_UPI0001C3174B thymidylate kinase n=1 Tax=Conexibacter woesei DSM 14684
           RepID=UPI0001C3174B
          Length = 210

 Score =  116 bits (290), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 38/243 (15%), Positives = 67/243 (27%), Gaps = 51/243 (20%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           +     R + + G DG+G +T    L   L  R                  +++ P  G 
Sbjct: 1   MTPARGRFVVVEGLDGAGTTTQAERLAAMLRTRGGHAV------------ELTKEPTNG- 47

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYK----FRKMLCKSQQGFLLITD 124
           P G  LR                    +    +  RA         ++     G  +++D
Sbjct: 48  PLGAVLRQAI-------EGRVALDPVALALAFAADRADHLFNPVNGVVAALDAGRWVVSD 100

Query: 125 RYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF 184
           RY    +   R          GG    + + +   +         P L + + +D +   
Sbjct: 101 RYVLSSLAYNR----------GGVVSREWVAELNARAIA------PDLTVFVDVDPEICL 144

Query: 185 ARK-----------PDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIH 233
            R               QL A+                +  +DG    D +  A   A+ 
Sbjct: 145 ERIGARSSADELFHSREQLVAVDRNYRDLIAAGHVHGPLATVDGSGSIDAVHDAIWTAVG 204

Query: 234 AAL 236
            AL
Sbjct: 205 EAL 207


>UniRef50_C1TMC0 Thymidylate kinase n=2 Tax=Synergistaceae RepID=C1TMC0_9BACT
          Length = 213

 Score =  116 bits (290), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 35/243 (14%), Positives = 75/243 (30%), Gaps = 45/243 (18%)

Query: 4   RNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQL 63
           R +S+ + +    I++ G DG GKST    L + L  R  +  +         G  I ++
Sbjct: 2   RQLSLAHRS-GLFISLEGIDGCGKSTQAMLLRDHLEERGRSVVLTKEPGDWSHGGEIRRI 60

Query: 64  PVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLI 122
            + G     +                       ++L    R     + ++    +G ++I
Sbjct: 61  LLGGDLRHEHTE---------------------LFLFMADRCEHLLQVVIPALDRGDIVI 99

Query: 123 TDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQT 182
            DRY    +    F G  L  T     +             W    +P +   + +    
Sbjct: 100 CDRYTDSTLAYQCF-GRGLDPTFVEGLF------------NWSDFPVPDVTFWIDVPLSC 146

Query: 183 AFARKPDHQLAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIH 233
           +  R          E+ +       +G          +I+ +DG    + +    + ++ 
Sbjct: 147 SLGRISSRGSLDRMEEDSDFLDRVRSGFQSLRESYEDRIIRIDGEGEENVVFSRLMESLE 206

Query: 234 AAL 236
             +
Sbjct: 207 GLI 209


>UniRef50_Q1J3J7 Thymidylate kinase-like protein n=1 Tax=Deinococcus geothermalis
           DSM 11300 RepID=Q1J3J7_DEIGD
          Length = 436

 Score =  116 bits (289), Expect = 8e-25,   Method: Composition-based stats.
 Identities = 50/224 (22%), Positives = 81/224 (36%), Gaps = 36/224 (16%)

Query: 17  IAIVGCDGSGKSTLTASLVNEL-AARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +A +G DG+GKS++ A + N++  A    +  +L  S GR           G P G  + 
Sbjct: 234 VAFLGPDGAGKSSVIAEVENKVAPAFRRLKRYHLRPSFGR-----------GHPSGEAV- 281

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQV---EVP 132
              +  H K     G+  A ++  L+ +       +     +  L+I DRY      +  
Sbjct: 282 ---SDPHGKAPRGSGSSLAKLLLWLADYTVGSVPAVRLPLVRSTLVIFDRYYHDLLVDAR 338

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQL 192
            +R+ GP              L     +     A   P L I L +  + A ARKP+  L
Sbjct: 339 RYRYGGPA------------WLAGLVGR-----AVPRPDLFIFLDLPAEVAHARKPEVPL 381

Query: 193 AALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
              +       QL         +D   P DE+ +     I   L
Sbjct: 382 EEGRRLRERYRQLARQLPNAHVVDAERPLDEVAREVETIILHHL 425


>UniRef50_C6HZ31 Thymidylate kinase n=1 Tax=Leptospirillum ferrodiazotrophum
           RepID=C6HZ31_9BACT
          Length = 220

 Score =  116 bits (289), Expect = 8e-25,   Method: Composition-based stats.
 Identities = 39/247 (15%), Positives = 71/247 (28%), Gaps = 57/247 (23%)

Query: 10  NSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAP 69
           +S P R+I + G DGSGKST    L + L ++        G             P+I   
Sbjct: 7   HSYPGRLIVVEGIDGSGKSTQLDLLSDYLQSKG------FGVLKSAWNSSPDISPII--- 57

Query: 70  FGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQV 129
                        +K    P   + L     S    Y   ++L   + G ++++DRY   
Sbjct: 58  ---------RKAKKKQVLTPYAFSLLHAADFSFRYTY---EILPAMEAGMIVLSDRYIY- 104

Query: 130 EVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK-- 187
                      +A+          L      L  +  + +P L     +D +T++ R   
Sbjct: 105 ---------TAIARDCARGLPRPWL------LSNFNFAIVPDLTFLFRVDPETSYQRITR 149

Query: 188 ------------------PDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASL 229
                             P       Q ++               +D     ++      
Sbjct: 150 TRSIKFYEAGLDMELSTDPRESYILFQSRVLAEYDNLRETHGFHVVDATLSLEKTQTRMR 209

Query: 230 RAIHAAL 236
           R +   +
Sbjct: 210 RLLSPII 216


>UniRef50_Q1H169 Thymidylate kinase n=2 Tax=Methylophilales RepID=KTHY_METFK
          Length = 203

 Score =  115 bits (288), Expect = 9e-25,   Method: Composition-based stats.
 Identities = 37/232 (15%), Positives = 71/232 (30%), Gaps = 43/232 (18%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            R I + G DG+GKS+   S+V+ L  R                   ++ P  G P G  
Sbjct: 3   GRFITLEGMDGAGKSSHIESIVSVLEGRGLEVVS-------------TREPG-GTPLGEK 48

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           LR    H      T         + + +  R +    +     +G  +++DR+       
Sbjct: 49  LRELLLHERMHVETET-------LLMFAARREHIAEVIEPALARGAWVVSDRFTD---AS 98

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR------- 186
           F +              ++     +           P L +   +  + + AR       
Sbjct: 99  FAYQCGGRGVPCEKVEALEAWVHPD---------LQPDLTLLFDVPVEISVARLAAARTP 149

Query: 187 -KPDHQLAALQEKIAVTP--QLTFNGAKILELDGRHPADEILQASLRAIHAA 235
            K + + A    +I      +      +   +DG  P D + +  L  +   
Sbjct: 150 DKFERESAEFFRRIRNGYLARAEAQPQRFRLIDGNRPMDTVRKEVLDIMREF 201


>UniRef50_Q2NIY4 Thymidylate kinase n=4 Tax=Candidatus Phytoplasma RepID=KTHY_AYWBP
          Length = 207

 Score =  115 bits (288), Expect = 9e-25,   Method: Composition-based stats.
 Identities = 34/234 (14%), Positives = 72/234 (30%), Gaps = 47/234 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I+  GC+G+GK+T ++ L  +L+ +                  +++ P  G  F   +R
Sbjct: 2   FISFEGCEGTGKTTHSSYLFEKLSKKYSCV--------------LTKEPGGG-LFNEVIR 46

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
           +   H + K              L +  RA    K ++   QQ  ++I DRY    +   
Sbjct: 47  NILLHSYNKQIDFH-----TEALLFAADRAEHLSKLIIPALQQNKIVICDRYLDSTIAYQ 101

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
            +                 +         +M    P +   L +D +    R    +   
Sbjct: 102 VY---------ARGLSKDFVLNINNLALNYM----PNITFYLDLDPKIGIQRVKQFRPKE 148

Query: 195 LQ----------EKIAVTPQLTFNG---AKILELDGRHPADEILQASLRAIHAA 235
           +           +K+       +      +I  +D     ++I     + +   
Sbjct: 149 INSFDLQKLSFHKKVRKGYLDLYQKDQQKRIFLIDASKSLEKIYNIIEQKLKEV 202


>UniRef50_B7IHT2 Thymidylate kinase n=10 Tax=Thermotogaceae RepID=KTHY_THEAB
          Length = 201

 Score =  115 bits (288), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 35/230 (15%), Positives = 67/230 (29%), Gaps = 41/230 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            IA  G DGSGKST    L   L ++                + ++     G   G  +R
Sbjct: 2   FIAFEGIDGSGKSTQLNLLSQYLKSKGK--------------KVLNIREPGGTILGEKIR 47

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
                 +   +          + L    RA    + +    ++GF ++ DR+    +   
Sbjct: 48  EILLDNNLNINKRSE------LLLFLASRAQLVEEVIKPHLKRGFFVLADRFSDSSIA-- 99

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
            + G            +               +  P ++  + I  + A  R  D  L  
Sbjct: 100 -YQGGARNIGVETVSTLN---------DFATDNIYPDIVFYIDIPTKIAMERLKDKNLDR 149

Query: 195 LQEKIAVTPQLTFN--------GAKILELDGRHPADEILQASLRAIHAAL 236
           L+++  +  +   N              +DG    D +       +   L
Sbjct: 150 LEKEGQIFLEKVRNTYLKLSKLRDNFFIIDGTKSIDNVFAEIKSIVEKHL 199


>UniRef50_D1N6G6 Thymidylate kinase n=1 Tax=Victivallis vadensis ATCC BAA-548
           RepID=D1N6G6_9BACT
          Length = 219

 Score =  115 bits (288), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 32/243 (13%), Positives = 71/243 (29%), Gaps = 43/243 (17%)

Query: 8   IINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIG 67
           + ++ P R+I   G +G+GKST    L   L  +                   ++ P  G
Sbjct: 5   LKHTHPGRLITFEGPEGAGKSTQLKLLAGYLEEKGFEV-------------IATREPG-G 50

Query: 68  APFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYP 127
            P    LR+       +      + T  ++ + +    +    +      G +++ DRY 
Sbjct: 51  TPLAERLRAVIKAFEGEEK---LHNTTELLLIEAARSQHVREVIRPALAAGKIVLCDRYF 107

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR- 186
                   + G                   +      +A   P L +   +  +  FAR 
Sbjct: 108 DSTTA---YQGGARGFDAE---------AIDALNDLAIAECAPDLTLLFDLTPEAGFART 155

Query: 187 -----------KPDHQLAALQEKIAVTPQ--LTFNGAKILELDGRHPADEILQASLRAIH 233
                      + + +      ++  +          ++  +    PA EI     + + 
Sbjct: 156 RTRTETQGEHDRFEEEKLEFHRQVRESYLTIAAREPERVRVVAADRPAQEIQTEVRKLVD 215

Query: 234 AAL 236
             +
Sbjct: 216 ELI 218


>UniRef50_Q1NU71 Putative uncharacterized protein n=1 Tax=delta proteobacterium
           MLMS-1 RepID=Q1NU71_9DELT
          Length = 432

 Score =  115 bits (288), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 44/233 (18%), Positives = 77/233 (33%), Gaps = 19/233 (8%)

Query: 8   IINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIG 67
           IIN   + V+A+ G DGSGKST    L   +          L       G    +     
Sbjct: 214 IINKKGI-VVAVEGIDGSGKSTFIDVLNKSIPKEG----RELFVQKSMAGRGFWRYSNKI 268

Query: 68  APFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYP 127
               R    +   ++         I  ++         + F +       G  +I DRY 
Sbjct: 269 RTIWRRSCDRPGKMNSVLKNGLLPIVFIIEI---GSLYFLFLRSRQLKNSGKNVIFDRY- 324

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK 187
              +   R       +  G N +I++L    ++ +       P + + L +D   A+ RK
Sbjct: 325 -ACLHYIRQRVHNKNRFVGKNLYIQLLYLLSVRWF-----PSPDVFVYLNVDPLVAYERK 378

Query: 188 PDHQLAALQEKIAVTPQ----LTFNGAKILELDGRHPADEILQASLRAIHAAL 236
            +  +  L EK  +  +    L     +   +D   P + I+   L      L
Sbjct: 379 KEDHVDELMEKYLIYNKEVVPLYDKITECFIVDSTLPTEVIVSRFLSVYWQRL 431


>UniRef50_A7ANS1 Thymidylate kinase, putative n=1 Tax=Babesia bovis
           RepID=A7ANS1_BABBO
          Length = 237

 Score =  115 bits (287), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 34/222 (15%), Positives = 63/222 (28%), Gaps = 38/222 (17%)

Query: 19  IVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLRSKA 78
             G D SGKST    L  +L  +     +          ++       G     +L S  
Sbjct: 18  FEGIDRSGKSTQVKLLSQKLTDKGIDHKLL---------KFPCYETECGKMLATHLASHG 68

Query: 79  AHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFRFDG 138
           A    +           +  L S  R    ++++     G  +I DRY    V       
Sbjct: 69  AVRSRR----------CIHLLFSANRWEMMKEIVATLVSGTHIIVDRYAFSGVAY----- 113

Query: 139 PQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK----PDHQLAA 194
                    N   +     +  L        P L++ L      + AR       ++   
Sbjct: 114 ----SVGAENLSYEWCITADDGLLS------PDLVVYLDNPAAVSAARSNFGDERYEQEG 163

Query: 195 LQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
             E +    +   +     + D   P + + +A    + + L
Sbjct: 164 KLEAVRRVYEEFSSLPYWHKYDATLPQEVLSKAIYERVASVL 205


>UniRef50_B4S1N2 Thymidylate kinase n=4 Tax=Alteromonadales RepID=KTHY_ALTMD
          Length = 222

 Score =  115 bits (287), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 33/233 (14%), Positives = 75/233 (32%), Gaps = 39/233 (16%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I + G +G+GKS++   +V  L        +   +  G            G P    
Sbjct: 3   GKFIVVEGLEGAGKSSVIGLIVKALTDAG--MRVEQTREPG------------GTPMAEA 48

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           +R    H  ++  +        ++ + +        K+      G  ++ DR    ++  
Sbjct: 49  IRECVKHDWDETVSEETE----LLLMYAARVQLLTNKIYPSLNAGAWVVGDR---HDLSS 101

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-KPDHQL 192
             + G     +      I  +          +  + P L + L +D      R +   +L
Sbjct: 102 QAYQGGGRGVSEKTMTAISDIA---------LNGFKPDLTLYLDVDPAVGLERARGRGEL 152

Query: 193 AALQEK--------IAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
             +++          A    L  N   I+ ++   P +++ Q  +  I   +S
Sbjct: 153 DRIEQAGLGFFERTRARYLSLAENDESIIVVNAMQPMEQVHQDVISIIANYVS 205


>UniRef50_Q9HLZ2 Probable thymidylate kinase n=2 Tax=Thermoplasma RepID=KTHY_THEAC
          Length = 193

 Score =  115 bits (287), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 42/226 (18%), Positives = 78/226 (34%), Gaps = 44/226 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            IAI G DG+GK+TL   + N L        +Y+ +      E  +     G     +L+
Sbjct: 2   FIAIEGIDGAGKTTLARGIGNML--LGEGYRVYMTKEPTDGMENYA-----GDGVELFLK 54

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                                    +  R    R++    + G ++I DRY +     + 
Sbjct: 55  ------------------------FTINRYAHQREIDRHIKNGEIVICDRYIRSS---YA 87

Query: 136 FDGPQLAKTTGGNGWI-KMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLA- 193
           +    +A+  G +    + +          +    P + I + +DE+TA  R     L  
Sbjct: 88  YQFEGIAEFFGNSEKAWEWMDSV-----SEIIKIRPDVQIYVDVDEETAMERISRRGLRN 142

Query: 194 ---ALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                ++K+    Q+       L +DG    + I+  +   I A L
Sbjct: 143 PHFENEQKLRSVRQIYKGFQWDLIVDGGRDKEAIISETFEKIIARL 188


>UniRef50_B8DZY5 dTMP kinase n=1 Tax=Dictyoglomus turgidum DSM 6724
           RepID=B8DZY5_DICTD
          Length = 207

 Score =  115 bits (287), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 35/226 (15%), Positives = 69/226 (30%), Gaps = 39/226 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G DGSGK+T    L     ++     ++L +  G            G   G  +R
Sbjct: 6   FITFEGIDGSGKTTQALLLKEHFESKGY--KVHLTREPG------------GTDVGNKIR 51

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
               +                 +L    R      ++ K ++ +++I +RY    +    
Sbjct: 52  EILLNP------AFSINYWTEAFLYLASRVENTINIIKKLKENYVVICERYADSTLAYQG 105

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP-----DH 190
           +         G N  +++L +             P L I + +D + A  RK      + 
Sbjct: 106 Y---------GRNLPLELLVEMNQIA---TFGLKPNLTILIDLDPELALRRKKSFDRIER 153

Query: 191 QLAALQEKIA--VTPQLTFNGAKILELDGRHPADEILQASLRAIHA 234
           +      K+             + + + G     EI +  +  I  
Sbjct: 154 ENIEFYYKVRKGYLEIAKKEKERFIIIPGDLSKGEIFKRIVEEIER 199


>UniRef50_D1CF94 Thymidylate kinase n=1 Tax=Thermobaculum terrenum ATCC BAA-798
           RepID=D1CF94_THET1
          Length = 216

 Score =  115 bits (287), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 33/238 (13%), Positives = 65/238 (27%), Gaps = 48/238 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G +GSGK+T    L   L        + L +  G            G   G  +R
Sbjct: 2   FITFEGPEGSGKTTQARMLATALETL--QCKVVLTREPG------------GTLVGEEIR 47

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
                   K           ++ L S  RA   R  +      G ++I DRY       +
Sbjct: 48  KILLGPLGKD-----LDPKCILLLFSAARAQLVRHIIKPAIDSGKIVICDRYADSTRA-Y 101

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLA- 193
           ++ G  + +            + E  +        P +   L +  +    R+       
Sbjct: 102 QWGGDGIPRD-----------EVERAIQLGTEGLEPDITFYLDLSPEEGLRRRRTDSARG 150

Query: 194 -------------ALQEKIAVTPQLTFNGA--KILELDGRHPADEILQASLRAIHAAL 236
                           +++             +   +D     ++I +  +  ++  L
Sbjct: 151 AESGWNSMDARELEFHQRVREAYLSLAKEYSSRFYVIDAAGRIEDIHRTIIEIVNKKL 208


>UniRef50_Q1NMK0 Thymidylate kinase n=1 Tax=delta proteobacterium MLMS-1
           RepID=Q1NMK0_9DELT
          Length = 218

 Score =  114 bits (286), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 35/229 (15%), Positives = 62/229 (27%), Gaps = 44/229 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA+ G DG+GKST    L   L             + G  G ++ Q+            
Sbjct: 16  LIALEGIDGTGKSTQLKLLARRLRELGLEVVTTFEPTDGPHGRYLRQMF----------- 64

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
                                + L    R     + +      G +++TDRY        
Sbjct: 65  ----------KNRAQLPPKEELRLFIADRHDHVEQVIAPALAAGKVVLTDRYYFSTAAYQ 114

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
              G   A     N                  +  P L++ L        AR  + +  +
Sbjct: 115 GAAGHDPAAIIAENE---------------QFAPRPDLVLLLEAPPAVGIARVRELRGES 159

Query: 195 LQEKIAVTPQ-------LTFNGAKILELDGRHPADEILQASLRAIHAAL 236
           L +               +   ++I  +D     D++ Q     +   L
Sbjct: 160 LNDFEQEDYLRRVTAIFASLADSRIRRIDATGRLDQVQQRLWPPVAQLL 208


>UniRef50_B6BTX5 Thymidylate kinase n=1 Tax=beta proteobacterium KB13
           RepID=B6BTX5_9PROT
          Length = 201

 Score =  114 bits (286), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 36/230 (15%), Positives = 71/230 (30%), Gaps = 42/230 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G DG+GKST    + + L  +              I   +++ P  G   G  LR
Sbjct: 4   FITVEGIDGAGKSTHLEFIQSYLNKK-------------NIQNKLTREPG-GTEIGEKLR 49

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
               H          ++    + + +    +    +    Q    +I DR+        +
Sbjct: 50  QLLLH-------DDMDVGTETMMMFAARHEHLITVIQPALQSNISIICDRFTDASYAYQQ 102

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
                     G       ++  E  ++    +  P L     +D  TA +R  + +    
Sbjct: 103 ---------GGKGIDKSFVKSLEELVH---PNLTPDLTFLFDLDPDTAHSRISNERNLDK 150

Query: 196 QEK---------IAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
            EK           V  +L    ++   +D     D+I Q   + +   +
Sbjct: 151 FEKQSSTFFNGVRKVYLELAKAHSRFHVIDSSQTIDQIQQVISKKLDELV 200


>UniRef50_B7XIF1 Thymidylate kinase n=1 Tax=Enterocytozoon bieneusi H348
           RepID=B7XIF1_ENTBH
          Length = 205

 Score =  114 bits (285), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 38/234 (16%), Positives = 72/234 (30%), Gaps = 42/234 (17%)

Query: 6   MSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPV 65
           M I N      I + G D SGK+TL   +  ++ A                  +  +   
Sbjct: 1   MKIQNKN--LFIVLEGIDRSGKTTLCNLISKKINAVKFN--------------FPDRTTN 44

Query: 66  IGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDR 125
            G     +L+    +V  +       I   +  L    R  K   +L   +    +I DR
Sbjct: 45  TGKKIDNFLKQYCENV--ENIFDNKEINEKLHLLFRDNRLEKIPFILKTLEN-HDIICDR 101

Query: 126 YPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA 185
           Y              +  +       K ++  E  L       +P +   L ++ + +F 
Sbjct: 102 YSMS----------GIVYSISKGLNEKWVKDSEKDL------PIPDITFFLDVNPEISFK 145

Query: 186 RK----PDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAA 235
           R+      H     Q+K+        +    ++ D     + +L   L  I+  
Sbjct: 146 RQDFGNEIHDTIEFQKKVYENYLKNKDYMIFIKND---TIENMLNEILNYINRF 196


>UniRef50_C1YIK9 Thymidylate kinase n=1 Tax=Nocardiopsis dassonvillei subsp.
           dassonvillei DSM 43111 RepID=C1YIK9_NOCDA
          Length = 664

 Score =  114 bits (285), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 35/235 (14%), Positives = 70/235 (29%), Gaps = 42/235 (17%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
                I + G +G+GKST    L   L  +                   ++ P      G
Sbjct: 436 LAGAFIVVEGGEGAGKSTQVRELTVWLRDQGFEV-------------IGTRQP------G 476

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVE 130
                                    + L +  +A    +++L   ++G ++I+DRY    
Sbjct: 477 ATKLGMRLRGLLLDRENSHITPRAEVLLYAADKADHVQQEILPALRRGAVVISDRYVDSL 536

Query: 131 VPGFRFDGPQLA-KTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR--- 186
           +    + G      +           Q            +P L + L +  +   +R   
Sbjct: 537 LA---YQGSGRDLSSDEIRRISDWATQ----------GLVPDLTVLLDVRPEDGLSRLGG 583

Query: 187 ---KPDHQLAALQEKIAV--TPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
              + + + A   +++             + L LD R P D I +   R + + L
Sbjct: 584 PADRIEGEPAEFHDRVRRGFLELARAAPERYLVLDAREPQDRITREIQRRVRSLL 638


>UniRef50_Q2RZ38 Thymidylate kinase n=2 Tax=Rhodothermaceae RepID=Q2RZ38_SALRD
          Length = 221

 Score =  114 bits (285), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 39/234 (16%), Positives = 70/234 (29%), Gaps = 44/234 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           ++   G DGSGKST    L   L  R                  + + P  G      +R
Sbjct: 3   LLTFEGIDGSGKSTQAHRLNEHLQERGHK-------------TLLVREPG-GTELSEQVR 48

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEVPGF 134
           S                    + L S  R      ++    + G ++I DR+        
Sbjct: 49  SVLLEP------ALNVHPMAELLLFSAARTQLVTERIRPALEAGRIVICDRFYDSTTA-- 100

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH---- 190
            + G             + L+    ++       +P     + +D +TA AR+ +     
Sbjct: 101 -YQGAGRNVADP-----EWLQSFHRRVTD---GLVPDRTYLVELDPETARARRTEGNDAA 151

Query: 191 ------QLAALQEKIAVTPQ--LTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                 +  A   ++A         + A+I  LDG    + +       + A L
Sbjct: 152 GDRMEAEDEAFYHRVAAAYDTLADEHSARIHRLDGHRSIEALHAEIRGDVEALL 205


>UniRef50_Q0BT79 Thymidylate kinase n=6 Tax=Alphaproteobacteria RepID=Q0BT79_GRABC
          Length = 250

 Score =  114 bits (285), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 41/242 (16%), Positives = 78/242 (32%), Gaps = 50/242 (20%)

Query: 10  NSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAP 69
           +S+  R I + G +G+GKST T +L   L +               I   +++ P  G  
Sbjct: 32  SSSSGRFITLEGGEGAGKSTQTRALAEALESLG-------------IRTLVTREPG-GTE 77

Query: 70  FGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQV 129
               LRS   +  +          A  +   +    +  R +    +QG  ++ DRY   
Sbjct: 78  GAEQLRSLLLYGPDWDGL------AETLLHFAARAQHVARTIRPALEQGIWVLCDRYYDS 131

Query: 130 EVPGFRF-DGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP 188
            +    +  G    +    + W+                  P + + L    + +  R  
Sbjct: 132 TMAYQGYCQGADRQRIAALSAWL---------------GLDPEVTLVLDAPVEASVQRLA 176

Query: 189 DH--------QLAAL------QEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHA 234
                     +   L      Q + A       +  + + LDG  P  E+ + +L A+  
Sbjct: 177 TRSGTLTVADRYERLGKPFFEQVRAAFLDIAASSPQRCVVLDGIRPPAEVTRMALAALAE 236

Query: 235 AL 236
            L
Sbjct: 237 KL 238


>UniRef50_Q13YY3 Thymidylate kinase n=7 Tax=Burkholderiales RepID=KTHY_BURXL
          Length = 206

 Score =  114 bits (284), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 33/230 (14%), Positives = 68/230 (29%), Gaps = 39/230 (16%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I   G DG+GK+T  +     L  +          +S      +++ P  G P G  
Sbjct: 4   GKFITFEGIDGAGKTTHLSWFRERLEQK---------VASTGRSVVMTREPG-GTPLGEQ 53

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           +R    H      T         + + +  R +    +     +G  +++DR+       
Sbjct: 54  IREIVLHQKMDLETE-------ALLMFALRRQHLAEVIEPALARGDWVLSDRFTD---AT 103

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP----- 188
           F + G               L   E  +      + P L +   +D + A  R+      
Sbjct: 104 FAYQGGG------RGLPRDKLETLERWV---QGGFQPDLTVLFDLDPEVASERRSAARDP 154

Query: 189 ---DHQLAALQEKIA--VTPQLTFNGAKILELDGRHPADEILQASLRAIH 233
              + +  A   +       +      +   +D      +I +     I 
Sbjct: 155 DRFESESEAFFSRTRAEYLRRAEEAPYRFAIIDSAQSIAQIQRRLEELIA 204


>UniRef50_A6UTV9 Probable thymidylate kinase n=2 Tax=Methanococcales
           RepID=KTHY_META3
          Length = 196

 Score =  114 bits (284), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 34/233 (14%), Positives = 72/233 (30%), Gaps = 57/233 (24%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           + I   G DGSGK+T    L + L      E      ++G IG+ I ++   G    +  
Sbjct: 3   KFIVFEGIDGSGKTTQAKLLADYLNGIYTCE-----PTNGEIGQLIRKVLG-GKNCEK-- 54

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
                                +  L +  R    +++  K  +  ++I DRY    +   
Sbjct: 55  -------------------ESLALLFAGDRVEHIKEIEHKLIEN-MVICDRYVYSSMVYQ 94

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
              G  +      N + K+                P +LI L +  + +  R  D     
Sbjct: 95  SIQGIDIDFIASINRFAKI----------------PDVLIYLDVSIEESLKRMGDRDSKE 138

Query: 195 LQEKIAVTPQLTFN------------GAKILELDG-RHPADEILQASLRAIHA 234
           + E   +  ++                   + ++      +E+ +  ++ +  
Sbjct: 139 IFENKEILQKVNKKYMNIINERLFEPKNGYILINTDNKTVEEVHKEIIKKLMD 191


>UniRef50_Q6L016 Probable thymidylate kinase n=1 Tax=Picrophilus torridus
           RepID=KTHY_PICTO
          Length = 202

 Score =  114 bits (284), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 35/242 (14%), Positives = 79/242 (32%), Gaps = 54/242 (22%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           +       IAI G DGSGK+TL   + +                    G ++++ P    
Sbjct: 1   MIDNGSMFIAIEGIDGSGKTTLAGDIASY------------------TGFYLTREP-TDR 41

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQ 128
               Y+ +                  +  +L +  R    +++      G  +I+DRY  
Sbjct: 42  FCYDYIEADYNDESS----------IINFFLFTLDRYMHQKEIKNHLING--VISDRYVF 89

Query: 129 VEVPGFRFDGPQLAKTTGG-NGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK 187
             +    + G  + K     +  I  +      +       +P L+I L ID   A  R 
Sbjct: 90  SSIA---YQGSGMEKRFKNMDETISWMLDVSRFI------IMPDLIIYLKIDPGIALKRL 140

Query: 188 PDHQLA----------ALQEKIAVTPQLTFNG---AKILELDGRHPADEILQASLRAIHA 234
              +             + + ++      F+G     +++++     + +   +++ ++ 
Sbjct: 141 NLRKNEKKNTDAFERLEMLKNVSKYYDYIFSGIIKIPVIKINAEMEYNYVKDEAIKGLND 200

Query: 235 AL 236
            L
Sbjct: 201 YL 202


>UniRef50_C5NX74 Thymidylate kinase n=1 Tax=Gemella haemolysans ATCC 10379
           RepID=C5NX74_9BACL
          Length = 208

 Score =  114 bits (284), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 32/234 (13%), Positives = 69/234 (29%), Gaps = 41/234 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I + G DGSGK++        L  +                + I+     G  F   
Sbjct: 3   GKFITVEGSDGSGKTSFINFATEYLKEKGY--------------KVITTREPGGTEFSEK 48

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           +R               +     +   +  R +  +K+L     G+++I DR+    V  
Sbjct: 49  VRELLFDSSNDIDAKTES-----LLFCASRRDHIVKKILPHVNDGYIVICDRFVDSSVAY 103

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-KPDHQL 192
             +         G     + +            +  P L +   +D +   AR K     
Sbjct: 104 QSY---------GRGLSKQDILNINSYATD---NLEPDLTLYFCVDVEVGLARTKNRDDN 151

Query: 193 AALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAALS 237
             + ++     +    G          +I  +D     + + + +L  +   L+
Sbjct: 152 NRMDQESLDFYKNVKRGYDDLSRENTERIKVIDASDTYENVQKKALAILEGFLN 205


>UniRef50_A1ZN65 Thymidylate kinase n=1 Tax=Microscilla marina ATCC 23134
           RepID=A1ZN65_9SPHI
          Length = 232

 Score =  113 bits (283), Expect = 4e-24,   Method: Composition-based stats.
 Identities = 34/224 (15%), Positives = 66/224 (29%), Gaps = 29/224 (12%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           + P + I I G DGSGKST    +   L               G            G   
Sbjct: 2   TKPNKFIVIEGLDGSGKSTQLKLITAHLQNAGIKYQHIHFPVMGEGY--------YGQLT 53

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVE 130
             +LR     + +           +   + +  R     ++      G+++I DRY    
Sbjct: 54  AEFLRGDLGALDQ-------VHPKIAALIFAGNRVEHLEQINQWLADGYVVIADRYVNSN 106

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH 190
           +    F   +    T  +   K + + E   Y++     P   + L +    +  +   +
Sbjct: 107 IA---FQCAKFDNQTEKDTLKKWILEFE---YEFNLLPRPASSLFLDV-PFASIKKSLTN 159

Query: 191 QLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHA 234
           Q                 G   +  D     +++ Q  L+ +  
Sbjct: 160 QREGDDRAY-------LQGKSDIHEDSLDLQEKVRQEYLQMVKE 196


>UniRef50_C7RBH0 Thymidylate kinase n=5 Tax=Gammaproteobacteria RepID=C7RBH0_KANKD
          Length = 216

 Score =  113 bits (283), Expect = 4e-24,   Method: Composition-based stats.
 Identities = 33/239 (13%), Positives = 72/239 (30%), Gaps = 42/239 (17%)

Query: 8   IINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIG 67
           +   +  + I I G +G GKST  A +     A+              I    ++ P  G
Sbjct: 1   MTTQSRGKFITIEGTEGVGKSTNIAFIKAWFEAK-------------NISLLHTREPG-G 46

Query: 68  APFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYP 127
            PF   +R       E+           ++ + +    +  +K+    +Q   ++ DR+ 
Sbjct: 47  TPFAEEIRELLLSQREEQVDAKSE----LLLMYAARAQHVSQKIKPALEQRQWVLCDRFS 102

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIK-MLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR 186
                 F + G   A        +   + +           + P L I L +  +   +R
Sbjct: 103 D---ASFAYQGAGRALGLNKLSELDQWVLE----------GFKPDLTILLDLPVEVGLSR 149

Query: 187 KPDHQ----------LAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAA 235
             +                Q +            ++  +D R   +++ Q   + +   
Sbjct: 150 AQERGPIDRFEEEKVEFFEQVRQGYLQIAQQEPERMKIVDARGSLEKVQQQIEQVLIHF 208


>UniRef50_A3EQU8 Thymidylate kinase n=2 Tax=Leptospirillum sp. Group II
           RepID=A3EQU8_9BACT
          Length = 217

 Score =  113 bits (282), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 43/247 (17%), Positives = 70/247 (28%), Gaps = 57/247 (23%)

Query: 10  NSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAP 69
           +S P R+I + G DGSGKST    L N L  +          SS  I   I         
Sbjct: 4   HSFPGRLIVVEGIDGSGKSTQIELLENYLRIKGFGVLRNAWNSSQEISPIIK-------- 55

Query: 70  FGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQV 129
                        +K    P   + L     S    +   ++L     G ++++DRY   
Sbjct: 56  ----------KAKKKQLLTPYGFSLLHAADFSYRYTH---EILPALNAGKIVLSDRYIY- 101

Query: 130 EVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR--- 186
                      +A+          L         +  +  P L     +D   A+ R   
Sbjct: 102 ---------TAIARDAARGIPRDWLVN------NFRFAIRPDLTFFFRMDPALAYDRITQ 146

Query: 187 -----------------KPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASL 229
                             P       Q ++    +          LDG  P +E  +   
Sbjct: 147 VRDIKYYEAGLDMELSMNPRESYILFQSRVLEGYENLAKEHGFSVLDGAKPVEETQRVVR 206

Query: 230 RAIHAAL 236
           R ++  +
Sbjct: 207 RLVNPLI 213


>UniRef50_C9RA68 Thymidylate kinase n=1 Tax=Ammonifex degensii KC4
           RepID=C9RA68_AMMDK
          Length = 202

 Score =  113 bits (282), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 39/228 (17%), Positives = 73/228 (32%), Gaps = 41/228 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G DG GK+T    L  +L  +             R+GE I +L            
Sbjct: 5   FIVLEGIDGVGKTTQARILAQKLREQGREVVEVREPGGTRLGEAIRELL----------- 53

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
                                  L    RA    + +     +G +++ DR+    +   
Sbjct: 54  -----------QKEELAPWAEACLFLASRAQLVEEVIKPALAKGKVVVGDRFSLSTLAYQ 102

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
              G +  K    N W+                  P L + + +  + A AR        
Sbjct: 103 GALGLEPDKLAQLNSWV-------------TGGLEPDLTLVIDLKAEEALARGKGDLREE 149

Query: 195 LQEKIAVTPQLTFN-----GAKILELDGRHPADEILQASLRAIHAALS 237
           +++K+ +  +   N      AK+L +DG+   +E+ +     +  AL+
Sbjct: 150 IRQKLEIVRERYLNLAKERAAKVLVVDGQGSVEEVSRRIWALVEEALA 197


>UniRef50_Q2NHE3 Probable thymidylate kinase n=1 Tax=Methanosphaera stadtmanae DSM
           3091 RepID=KTHY_METST
          Length = 195

 Score =  113 bits (282), Expect = 6e-24,   Method: Composition-based stats.
 Identities = 41/225 (18%), Positives = 69/225 (30%), Gaps = 39/225 (17%)

Query: 17  IAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLRS 76
           I + G DG GK+T T  L   L  R  +    +  +   IG+ I +  +           
Sbjct: 3   IVLEGIDGVGKTTQTEKLKEWLEKRGFSVKTIVEPTDSDIGKIIREELL----------- 51

Query: 77  KAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLC-KSQQGFLLITDRYPQVEVPGFR 135
                  KP         ++  L +  R     ++   K+ Q  +LI+DR          
Sbjct: 52  -------KPEATSDTNQQMLALLFAADRLTLKDEINQVKNNQQKILISDR---SFYSSIT 101

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---KPDHQL 192
           +      +        + + +          +  P L I L IDE  A  R       + 
Sbjct: 102 YQNSTTIEP-------EWIYKINKH------TPRPDLTIILDIDEDEALKRCDKIDTFEN 148

Query: 193 AALQEKIAVTP-QLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
               EK      +L      I+++D     D +       I   L
Sbjct: 149 KEFLEKTRENYLKLVKTEKNIVKIDATPTEDVVQDEIRNQIIKYL 193


>UniRef50_A6VXL0 Thymidylate kinase n=2 Tax=Marinomonas RepID=KTHY_MARMS
          Length = 212

 Score =  113 bits (282), Expect = 6e-24,   Method: Composition-based stats.
 Identities = 31/230 (13%), Positives = 73/230 (31%), Gaps = 40/230 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I++ G +GSGK+T    +   L                +I   +++ P  G P    
Sbjct: 3   GKFISLEGGEGSGKTTAIHFIRQWLDDH-------------KIPYIMTREPG-GTPLAEE 48

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           +R       ++           ++ + +    +   K+    ++G  +I+DR+       
Sbjct: 49  IRQLVLTPRDESVNDVTE----LLLVFAARAQHLAEKIQPALEKGTWVISDRFLDSS--- 101

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR------- 186
           + + G          G I ML Q        +    P   + L +  +    R       
Sbjct: 102 YVYQG------KARGGDIAMLDQL---ANWVVGDNKPDATLVLDVPVELGQERVVQRQHQ 152

Query: 187 -KPDHQLAALQEKIAV--TPQLTFNGAKILELDGRHPADEILQASLRAIH 233
            + D +  A  +K+      +   +  ++  +D     + +       + 
Sbjct: 153 DRLDKESFAFHQKVRDGFLERAEADPKRVKIVDASQSLESVKSQIEEQLA 202


>UniRef50_Q5F9Z5 Thymidylate kinase n=59 Tax=Betaproteobacteria RepID=KTHY_NEIG1
          Length = 206

 Score =  113 bits (281), Expect = 7e-24,   Method: Composition-based stats.
 Identities = 34/232 (14%), Positives = 70/232 (30%), Gaps = 41/232 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I + G DG+GKST  A +      R              +    ++ P  G P G  
Sbjct: 3   PQFITLDGIDGAGKSTNLAVIKAWFERRG-------------LPVLFTREPG-GTPVGEA 48

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           LR    +   K       + A  + + +    +    +L     G  +++DR+       
Sbjct: 49  LREILLNPETKAG-----LRAETLMMFAARMQHIEEVILPALSDGIHVVSDRFTD---AT 100

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD-HQL 192
           F + G      +     ++   Q             P L + L +  + + AR     + 
Sbjct: 101 FAYQGGGRGMPSEDIEILEHWVQ---------GGLRPDLTLLLDVPLEVSMARIGQAREK 151

Query: 193 AALQEKIAVTPQLTFN---------GAKILELDGRHPADEILQASLRAIHAA 235
              +++ A                   +   +D     DE+  +  + +   
Sbjct: 152 DRFEQEQADFFMRVRGVYLDRAAACPERYAVIDSNRSLDEVRNSIEKVLDGH 203


>UniRef50_Q2J4Z0 Thymidylate kinase n=3 Tax=Frankia RepID=Q2J4Z0_FRASC
          Length = 730

 Score =  113 bits (281), Expect = 7e-24,   Method: Composition-based stats.
 Identities = 38/248 (15%), Positives = 67/248 (27%), Gaps = 57/248 (22%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
              IAI G DG+GKST    L   LA+      +        +G  + +L +        
Sbjct: 505 GLFIAIEGIDGAGKSTQVELLRTWLASSGREVVVTSESGGTALGTGLRELLLDPT----- 559

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVP 132
                                    L +  RA    + +     +G ++ITDRY    + 
Sbjct: 560 ---------------VRLHPRTEALLTAADRAEHVAQVIEPALARGAIVITDRYVDSFIA 604

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP---- 188
                  Q   T   +   +              + LP + + L +  +    R      
Sbjct: 605 FQSVS--QALSTDELSVLTQWA----------THALLPDVTVLLDLPAEIVLRRARMTAY 652

Query: 189 ------------------DHQLAALQEKIAVTPQLTFNGA--KILELDGRHPADEILQAS 228
                             D      Q ++  T +        + L LD     +EI    
Sbjct: 653 PDPPPGPPGPPDGPAEADDAGKLTFQGRVRDTFRRLAQKEPDRYLPLDATRSPEEIHAEI 712

Query: 229 LRAIHAAL 236
              + + +
Sbjct: 713 RSFMASRI 720


>UniRef50_Q0AIL5 Thymidylate kinase n=22 Tax=Betaproteobacteria RepID=KTHY_NITEC
          Length = 215

 Score =  113 bits (281), Expect = 8e-24,   Method: Composition-based stats.
 Identities = 33/232 (14%), Positives = 72/232 (31%), Gaps = 41/232 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I   G DG+GKST  A L + L  +                  +++ P      G  
Sbjct: 4   GKFITFEGIDGAGKSTHLAWLASFLRDKGLEV-------------IVTREPGS-TALGEQ 49

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           LR       +       +     + + +  R +  + +L   ++G  +I+DR+       
Sbjct: 50  LRQLLLDHRQ-----AMHAETETLLMFAARREHLDKVILPALERGAWVISDRFTD---AS 101

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR------- 186
           F + G      +     ++   Q           + P L +   +    +  R       
Sbjct: 102 FAYQGGGRGVPSARLEILEQWVQ---------KGFSPDLTVYFDVPVTISRQRVQSARTA 152

Query: 187 -KPDHQLAALQEKIAVTPQLTFNG--AKILELDGRHPADEILQASLRAIHAA 235
            + + +     E++             +I  +DG    +E+  A +  +   
Sbjct: 153 DRFELEPDLFFERVRQAYLQRAKQFSERIRVVDGSLSLEEVRTAMVEVVEKF 204


>UniRef50_B1I165 Thymidylate kinase n=3 Tax=Firmicutes RepID=KTHY_DESAP
          Length = 221

 Score =  112 bits (280), Expect = 9e-24,   Method: Composition-based stats.
 Identities = 36/233 (15%), Positives = 66/233 (28%), Gaps = 38/233 (16%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
               I   G DG+GK+T  A L   L +      +            +++ P  G   G 
Sbjct: 2   SGVFIVFEGIDGAGKTTQLAYLHEALLSMRNHRVL------------VTREPG-GTRIGE 48

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVP 132
            +R           T         +   +    +    +     +G ++++DR+    + 
Sbjct: 49  AVRRVLLDTGNSEMTGETE----ALLYAAARSQFTAEVVRPALARGEIVLSDRFLDSSLA 104

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQL 192
              F         G    +  LRQ     +       P L + L +    A AR    + 
Sbjct: 105 YQGF---------GRGLELHRLRQVN---FLATGGLRPDLTVLLDLPVAAAVARMDPDRR 152

Query: 193 AALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAAL 236
             L+ +     +    G            L ++    A     A    + A L
Sbjct: 153 DRLEREGVDFFERVRRGYLELASADPGHYLIVNAEREAGVCASAIWARVRALL 205


>UniRef50_Q2RMF8 Thymidylate kinase n=2 Tax=root RepID=Q2RMF8_MOOTA
          Length = 207

 Score =  112 bits (280), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 29/231 (12%), Positives = 66/231 (28%), Gaps = 38/231 (16%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
              I + G DGSGK+T    L   L  R              + E I +L +        
Sbjct: 4   GLFITLEGPDGSGKTTQMDRLEEYLHRRGLAVERTREPGGTLLSEAIRRLLL-------- 55

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
                     +PS  P +  A +    +    +   ++      G +++ DR+    +  
Sbjct: 56  ----------EPSYSPVDARAELFLYAAARAQHVAERIRPALAAGKIVLCDRFSDSTLAY 105

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR------K 187
             +         G     +++ +          +  P +   + +       R      +
Sbjct: 106 QGY---------GRQLGAELVERLNDLA---TGNLRPDITFLIDVPVAIGLGRHSGGSDR 153

Query: 188 PDHQLAALQEKIA--VTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
            + +      ++             ++  +DG    D + +     + A L
Sbjct: 154 LEQEDLEFHRRVRQGYLDLARREPRRVHLIDGTPSPDVVWEEIKEILDARL 204


>UniRef50_C7RD91 Thymidylate kinase n=6 Tax=Clostridiales Family XI. Incertae Sedis
           RepID=C7RD91_ANAPD
          Length = 209

 Score =  112 bits (280), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 40/235 (17%), Positives = 69/235 (29%), Gaps = 42/235 (17%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
             ++I   G DGSGK+T+   +   L         +                  G P   
Sbjct: 2   TGKLIVFEGPDGSGKTTVINEVKKRLKKDQIEYLDFREPG--------------GTPISE 47

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEV 131
            +R        +  T           L +  RA     K+    ++G L+I DR+    +
Sbjct: 48  KIREIIIDNDNEDMTSRCEC-----LLFAASRAQLIEEKIRPALEKGKLVICDRFVLSSL 102

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK-PDH 190
               + G            I               +    L I   ID +TA  RK  + 
Sbjct: 103 ---LYQGVGRGLGIEKVKVIN---------DFATENTKADLTIFFDIDYKTALVRKRANF 150

Query: 191 QLAALQEKIAVTPQLTFN---------GAKILELDGRHPADEILQASLRAIHAAL 236
               L+ +     +  F+           +I  +D     DE+    +  I+ +L
Sbjct: 151 SADRLESEDFDFHRKIFDAYLDITERYKDEIKRVDATKSIDEVTDQVMELIYKSL 205


>UniRef50_C4V663 Thymidylate kinase n=1 Tax=Selenomonas flueggei ATCC 43531
           RepID=C4V663_9FIRM
          Length = 231

 Score =  112 bits (279), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 32/242 (13%), Positives = 63/242 (26%), Gaps = 39/242 (16%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            ++  I   DGSGK T T  L   L                       ++ + G      
Sbjct: 4   GKLFIIEAGDGSGKETQTRLLAQRLIREGHRVRAVAFPDYEADASMPVRMYLRG------ 57

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQVEVP 132
                    +                 +  R   +R K     + G +++ DRY      
Sbjct: 58  ---------DFGMQADEVNPYAASTFFAVDRYASYRMKWRQDYEAGTIILADRYTTSN-- 106

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF----ARK- 187
                  ++      + ++  L   E   +  +   +P  +  L ++   A     AR  
Sbjct: 107 -MVHQAVKIRDAAERDAFLDWLDDFE---FNKLGLPVPDAVFFLDMEPCAAERLLTARAQ 162

Query: 188 ------PDHQLAA-LQEKIAVTPQLTFNGAKILELDGRH-----PADEILQASLRAIHAA 235
                   H+  A    +      L       + +         P +EI +     +   
Sbjct: 163 AKGETPDIHERDADYLRRTHDAYVLLTARCGWVRIPSSADGAPLPIEEIHERLYAEVGKF 222

Query: 236 LS 237
           L+
Sbjct: 223 LT 224


>UniRef50_B4S8U3 Thymidylate kinase n=11 Tax=Chlorobiaceae RepID=KTHY_PROA2
          Length = 223

 Score =  112 bits (279), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 36/237 (15%), Positives = 63/237 (26%), Gaps = 52/237 (21%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G DG+GKST    L   L ++                  ++     G      +R
Sbjct: 2   FITFEGIDGAGKSTQVKMLRKLLISKGLEV--------------LTLREPGGTDISESIR 47

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
                V               + L +  RA   +K +         ++ DR+        
Sbjct: 48  DILLEVKN------DITPIGELLLFAASRAELVQKVIKPALSDHATVLLDRFYDSTSAYQ 101

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK------- 187
            +         G    + +L Q          S  P +   L +  + A  RK       
Sbjct: 102 GY---------GRGLDLALLHQINRIAS---CSLEPDITFYLDLSPEDAMIRKFSEKSLP 149

Query: 188 ---PDHQLAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAI 232
               D +L  ++           NG          +++ +D     D I +     I
Sbjct: 150 LAFEDEELDRMERSGLEFYTRVRNGYQTIAASQPRRVVTIDATLEPDAIHRKITETI 206


>UniRef50_Q6AB62 Thymidylate kinase n=4 Tax=Actinomycetales RepID=KTHY_PROAC
          Length = 204

 Score =  112 bits (279), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 33/234 (14%), Positives = 71/234 (30%), Gaps = 41/234 (17%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
               +   G DG+GK+T    L   L                 I   +++ P   +  G+
Sbjct: 2   GGVFVVFEGGDGAGKTTQARLLDQWLTTEG-------------IPHLMTREPG-DSWLGQ 47

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEV 131
            +R         P +           L +  +A    + ++   ++G +++ DRY    +
Sbjct: 48  RIRELVLSPGSGPISSRAE-----ALLYNADKAQHVDEVVIPALREGKVVVCDRYVDSTI 102

Query: 132 PGFRFDGPQLA-KTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDE-----QTAFA 185
               + G   A                           +P + + L +D      + A  
Sbjct: 103 A---YQGAGRALDPGEVGQLACWA----------TTGLVPDVTVLLDVDPCEGAGKIAAK 149

Query: 186 RKPDHQLAA--LQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
            + +       L+ +         +  + L L+ R    EI +A  + +   L+
Sbjct: 150 DRLEAAGDEFHLRVRQHFLDLAAAHPQRYLVLNARKSRKEISEAIRQRVTGLLN 203


>UniRef50_Q2K893 Thymidylate kinase protein n=9 Tax=Rhizobium RepID=Q2K893_RHIEC
          Length = 236

 Score =  111 bits (278), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 28/241 (11%), Positives = 61/241 (25%), Gaps = 45/241 (18%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           ++S     +   G +G+GKST    L   L        +          E +  + + G 
Sbjct: 11  LSSGTGLFVTFEGGEGAGKSTQIRRLAEALKGEGHEVLVTREPGGSPGAEAVRHVLLSG- 69

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYP 127
                                   T +   L +  R     + +      G +++ DR+ 
Sbjct: 70  ------------------AAEAFGTRMEAILFAAARNDHVEEVIRPALAAGKIVLCDRF- 110

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK 187
                    D  ++ +   GN     +   +      +   +P   + L I  +    R 
Sbjct: 111 --------MDSSRVYQGITGNLDPDFIETLQRIAINGV---VPDCTLILDIPAKVGLERA 159

Query: 188 PDHQLAA-------------LQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHA 234
                A               + + A          +   ++     + I    L  +  
Sbjct: 160 QKRSAAEAPDRFEKERLETHEKRREAFLDIAAREPERCRVVNAMQTEEAIAAEILAIVKQ 219

Query: 235 A 235
            
Sbjct: 220 L 220


>UniRef50_Q55593 Thymidylate kinase n=7 Tax=Chroococcales RepID=KTHY_SYNY3
          Length = 212

 Score =  111 bits (278), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 40/239 (16%), Positives = 66/239 (27%), Gaps = 49/239 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G DGSGK+T    L+     +     +    ++G +G  I Q            R
Sbjct: 5   FIVLEGIDGSGKTTQGDLLLAHFQRQGLAAVLSPEPTNGPVGRLIRQALQGDLFTYNDAR 64

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK----MLCKSQQGFLLITDRYPQVEV 131
              A +                YL +  R Y        +  K  Q   +IT RY    +
Sbjct: 65  QFEAQMG---------------YLFAADRHYHLYHPGDGVEAKLAQQCHVITTRYYFSSL 109

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQ 191
                               + +++             P  +I L +    A  R  D Q
Sbjct: 110 AYNCH----------TEADWEFVQRLNQSF------PQPDWVIYLDLPVDLALQRLGDRQ 153

Query: 192 LAALQEKIAVTPQ--------------LTFNGAKILELDGRHPADEILQASLRAIHAAL 236
               Q       Q                    ++  LD   P +++ QA +  +   L
Sbjct: 154 QLEDQAPRECYEQREKLISVHRNYDRIFAHYQGQLCRLDASLPVEQLHQAIITKVEEML 212


>UniRef50_B2GAE1 Thymidylate kinase n=32 Tax=Lactobacillales RepID=KTHY_LACF3
          Length = 214

 Score =  111 bits (278), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 35/235 (14%), Positives = 75/235 (31%), Gaps = 41/235 (17%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
             R I+  G DG+GK+++  ++   L  ++  + +Y            ++ P  G P   
Sbjct: 2   SGRFISFEGPDGAGKTSVLTAIRTGLVNQLGDQVVY------------TREPG-GNPIAE 48

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVP 132
            +R+                    +   +  R +    +    + G L++ DRY    + 
Sbjct: 49  QVRAVLLDKQNGAMDDWTE----ALLYAASRRQHVVETLKPALEAGKLILCDRYLDSSIA 104

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQL 192
              + G            I  + +        +   LP L I L +  +T  AR    + 
Sbjct: 105 ---YQGGG------RELGIDRIWELNQYA---IDGLLPDLTIFLDLPVETGLARIEKGRA 152

Query: 193 AALQE------------KIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAA 235
             +              + A          +I++++       +++    AIHA 
Sbjct: 153 ETINRLDEQTTNFHRRVRQAYLTLAERFPERIVKVNADQELARVIEDVRSAIHAR 207


>UniRef50_Q5FUU6 Thymidylate kinase n=9 Tax=Acetobacteraceae RepID=KTHY_GLUOX
          Length = 214

 Score =  111 bits (277), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 35/235 (14%), Positives = 74/235 (31%), Gaps = 40/235 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
              I + G +G+GKST    L   L A      +          E I  L + G      
Sbjct: 5   GLFITLEGGEGAGKSTQARLLAEALRAEGHKVLLTREPGGTPGAEEIRNLLLFGK----- 59

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
                            +  A ++  ++    +    +L   ++G +++ DR+    +  
Sbjct: 60  --------------VDLSWRAEILMHMAARSDHLDNAILPALERGEIVVCDRFHDSTLA- 104

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH--Q 191
             + G  + +               L   + +  + P L + L +    A AR      Q
Sbjct: 105 --YQGYGIGQGAPEVLAF-------LNGARKLVDFEPDLTLMLELPRPQALARLKARGGQ 155

Query: 192 LAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAALS 237
               + +     +    G          ++  +D     + +  A L+A+H +L+
Sbjct: 156 TDRYEAQAEAFHERVLAGFDAIASADPVRVKRVDAGQTPEAVSAALLQAVHESLT 210


>UniRef50_C7DHA0 dTMP kinase n=1 Tax=Candidatus Micrarchaeum acidiphilum ARMAN-2
           RepID=C7DHA0_9EURY
          Length = 215

 Score =  111 bits (277), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 40/190 (21%), Positives = 63/190 (33%), Gaps = 38/190 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +IA  G DGSGKST    L + L +           +SG IG+ I ++ V   P      
Sbjct: 2   LIAFEGIDGSGKSTQAEMLDSYLKSSGIAAVTTAEPTSGPIGKLIKEIVVSKKPIN---- 57

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQVEVPGF 134
                               +  L +  RAY     ++    +G ++ITDRY        
Sbjct: 58  -----------------ALAMQMLFTADRAYHLETTIMPSISEGKVIITDRYI------- 93

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
              G  +A  T      + L     K         P +   +  + + A  R        
Sbjct: 94  ---GSTIAYGTAAGIDKRFLVGINRKF------IPPDITFVIDANPRKAVERLNRRAAEF 144

Query: 195 LQEKIAVTPQ 204
           L+ K A+  +
Sbjct: 145 LKNKTALMEK 154


>UniRef50_B2UBZ3 Thymidylate kinase n=13 Tax=Proteobacteria RepID=KTHY_RALPJ
          Length = 205

 Score =  111 bits (276), Expect = 3e-23,   Method: Composition-based stats.
 Identities = 39/233 (16%), Positives = 70/233 (30%), Gaps = 39/233 (16%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
             + I   G DG+GKST  A    +L A+          +       +++ P  G P G 
Sbjct: 2   TGKFITFEGIDGAGKSTHLAWFAQQLQAK---------LAPLGKKVVVTREPG-GTPLGE 51

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVP 132
            LR    H      T         + + +  R +    +      G  +I+DR+      
Sbjct: 52  RLREVLLHERMHLETE-------ALLMFASRREHIAEVIQPALDAGDWVISDRFTD---A 101

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD--- 189
            F + G            I  L   E  + Q      P   I   +  + A AR  D   
Sbjct: 102 TFAYQGGG------RGLAIDRLEALEHWVQQ---GLQPTKTILFDLAPEIAAARLADART 152

Query: 190 ---HQLAA----LQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAA 235
               +  +    L+ +     +      + + L+      +I +     +   
Sbjct: 153 PDKFEAESAQFFLRTRAEYLRRAAAEPDRFVVLNANRERSDIQKDLENLLATL 205


>UniRef50_A0JSU5 Thymidylate kinase n=2 Tax=Micrococcaceae RepID=A0JSU5_ARTS2
          Length = 226

 Score =  111 bits (276), Expect = 3e-23,   Method: Composition-based stats.
 Identities = 40/215 (18%), Positives = 63/215 (29%), Gaps = 34/215 (15%)

Query: 8   IINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIG 67
           +    P   IA  G DG+GKST  A+L   L +R                  +      G
Sbjct: 1   MTTQNPGLFIAFEGGDGAGKSTQAAALAGALDSRGI--------------RVLRTREPGG 46

Query: 68  APFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRY 126
            P G  LRS                      + +  RA    + +L   ++G +++TDRY
Sbjct: 47  TPIGEKLRSLVLDH-----GHGHIDARTEALIFAASRAAHADQVILPALERGEIVLTDRY 101

Query: 127 PQVEVPGFRFDGPQLAKTTGGNGWI-KMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA 185
               V    + G      T     + +                 P L + L +D      
Sbjct: 102 IDSSVA---YQGAGRDLGTAAVRDLNEWATS----------GLQPDLTVLLDVDPAVGRL 148

Query: 186 RKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHP 220
           R+     A  + +              L+L    P
Sbjct: 149 RRTAGDAAEDRMESEADEFHAKIRTAFLDLAADRP 183


>UniRef50_C8PCQ1 dTMP kinase n=1 Tax=Lactobacillus iners DSM 13335
           RepID=C8PCQ1_9LACO
          Length = 234

 Score =  110 bits (275), Expect = 3e-23,   Method: Composition-based stats.
 Identities = 33/235 (14%), Positives = 76/235 (32%), Gaps = 41/235 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
              I+  G DG+GK+T+   LV +L+++                  +++ P  G+     
Sbjct: 24  GYFISFEGPDGAGKTTIINELVQQLSSKTIAP------------ILVTREPG-GSKISEN 70

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           +R        K            +   +    +    ++     G ++ +DR+    +  
Sbjct: 71  IRKIILDPKNKEMNAETE----ALLYAAARSQHVIETIIPALNAGKIVFSDRFIDSSLA- 125

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD---H 190
             + G       G +  I  ++Q      + +    P L +   ID      R       
Sbjct: 126 --YQG------IGRDLGIDEIKQINEFATRHIT---PDLTLFFDIDPLKGLQRIQKVRPE 174

Query: 191 QLAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAAL 236
               L+++  +  Q  + G          +I  +D      E++  S++ +   +
Sbjct: 175 NEDRLEQENNLFHQKVYTGYKQLLSAYPERIKRVDAELSIAEVVSQSVKILEEYM 229


>UniRef50_B0S2F7 Thymidylate kinase n=3 Tax=Clostridiales Family XI. Incertae Sedis
           RepID=KTHY_FINM2
          Length = 203

 Score =  110 bits (275), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 34/230 (14%), Positives = 69/230 (30%), Gaps = 41/230 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G DGSGKST+   + + L                      ++ P  G+P    +R
Sbjct: 2   FITFEGPDGSGKSTIIQKVYDYL-------------IENNYDVIKTREPG-GSPIAEKIR 47

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
           +                      L +  RA    + +L    +  +++ DR+    +   
Sbjct: 48  NLILDTENIKMG-----YRTEALLYAASRAQHVEETILPALNENKIVLCDRFLISSLA-- 100

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD-HQLA 193
            + G            I+ +R         +    P  ++   +D  T   RK       
Sbjct: 101 -YQGVG------RGLGIENVRNINEFAINGVF---PDFVLFFDVDPITTLKRKSSLDTAD 150

Query: 194 ALQEKIAVTPQLTFNGAK--------ILELDGRHPADEILQASLRAIHAA 235
            L+++     +  +NG K        I  +D     +++    +  +   
Sbjct: 151 RLEKEGNNFHERVYNGYKEILNSEKNIEIIDATQSVEDVFSQCIEVLKRR 200


>UniRef50_C0W270 Thymidylate kinase n=1 Tax=Actinomyces coleocanis DSM 15436
           RepID=C0W270_9ACTO
          Length = 243

 Score =  110 bits (275), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 33/237 (13%), Positives = 67/237 (28%), Gaps = 41/237 (17%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           +N+ P   I   G +  GK+T      N L        +        +G+ +  L + G 
Sbjct: 16  LNNQPGLYITFEGGEACGKTTQIELTQNWLRDLGYQLTVSREPGGTELGQQLRNLILHG- 74

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYP 127
                              P        + L    RAY    K+    + G +++ DRY 
Sbjct: 75  -------------------PKDIDPRCEVLLYLADRAYHVATKIRPALEAGQVVVQDRYF 115

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK 187
              V    + G            + +           +   +P +   L ID + +  R+
Sbjct: 116 DSAVA---YQGAARKLGVSEVRDLNLWA---------VEGLIPEITFLLDIDPRVSMQRR 163

Query: 188 PD--HQLAA------LQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                ++        ++ +            +   L+     +E+       +  AL
Sbjct: 164 AGATDRIEEEPSAFHIKVREQYLALAAAEPQRFHVLNASDSIEELQAQIREVLLGAL 220


>UniRef50_B9JFC7 Thymidylate kinase n=4 Tax=cellular organisms RepID=B9JFC7_AGRRK
          Length = 227

 Score =  110 bits (275), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 32/244 (13%), Positives = 64/244 (26%), Gaps = 46/244 (18%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           +       ++  G +G+GKST    L   L        +          E +  + + G 
Sbjct: 1   MADATGLFVSFEGGEGAGKSTQIRRLAAWLRELGHDVLVTREPGGSPGAEAVRHVLLSG- 59

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYP 127
                                   T +   L +  R     + +      G +++ DR+ 
Sbjct: 60  ------------------AAEMFGTRMEAILFAAARNDHVEEIIRPALAHGTIVLCDRF- 100

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK 187
                    D  ++ +   GN     +   +      +   +P   + L I  +    R 
Sbjct: 101 --------MDSSRVYQGITGNLEPDFIEALQRVAVNGV---VPDCTLILDIPAELGLERA 149

Query: 188 PDH----------QLAALQ----EKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIH 233
                        +   LQ     + A       +  +   +D +   D I       I 
Sbjct: 150 RKRASADAAPDRFEKEELQTHEKRREAFLDIAARDPDRCHVVDAQRGEDVIADEIAAIIE 209

Query: 234 AALS 237
             LS
Sbjct: 210 KRLS 213


>UniRef50_B5Y7S6 Thymidylate kinase n=1 Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=KTHY_COPPD
          Length = 193

 Score =  110 bits (274), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 35/226 (15%), Positives = 75/226 (33%), Gaps = 44/226 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G DG GKST+ + L  E+  + P   ++     G + + + +  ++         
Sbjct: 2   FIVVEGIDGCGKSTVASLLAAEIGKKRP---VFHTFEPGHVRDGLYRELIM--------- 49

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
                          +   +V  L +  RA   +K +     +G  ++ +RY    +   
Sbjct: 50  ------------ENVDNPFVVAALFTIDRAEHVKKMIKPALAKGEWVVCERYADSTLA-- 95

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
            + G  +                     + +    P  +  L I+   A AR  + +  A
Sbjct: 96  -YQGYGMGLDKEL---------INRMNEEAIDGLWPDKIFYLDIEPHLALARLQNKEKDA 145

Query: 195 LQEKIAVTPQLTFNGAK-------ILELDGRHPADEILQASLRAIH 233
           L+ +     Q    G +        + +D   P + I++  L  + 
Sbjct: 146 LEGQGLEFLQRVREGYEEIARTRGYIYMDATLPPEIIVKRILEEVK 191


>UniRef50_B2A320 dTMP kinase n=1 Tax=Natranaerobius thermophilus JW/NM-WN-LF
           RepID=B2A320_NATTJ
          Length = 206

 Score =  109 bits (273), Expect = 5e-23,   Method: Composition-based stats.
 Identities = 29/235 (12%), Positives = 75/235 (31%), Gaps = 42/235 (17%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           S   + I   G DG GKST    + ++L                 +G+ I ++ +    +
Sbjct: 2   SKRGKFITFEGIDGCGKSTQLKKVTSKLKKLGFNVVSTREPGGTSVGDAIREILLAPKHY 61

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQV 129
              + ++A                    L +  R     + ++    +  +++ DR+   
Sbjct: 62  NMTIETEA-------------------LLYAASRVQHIEEFIIPNLAEDNIVLCDRFVDS 102

Query: 130 EVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR--- 186
            V    + G +L+           + +     Y  +    P +   + I  + A  R   
Sbjct: 103 SVA---YQGIKLSHEE--------VIRVNQPAYDKVT---PDITFLIDITPERAAKRLGI 148

Query: 187 ---KPDHQLAALQEKIAVTPQL--TFNGAKILELDGRHPADEILQASLRAIHAAL 236
              + +++    Q ++             +I+ ++G    +++ +     +   L
Sbjct: 149 EKDRIENRGVNYQSQVRENYLFLAEEEPDRIVIINGDQSEEKVFEELWNVLEDIL 203


>UniRef50_P59500 Thymidylate kinase n=5 Tax=Buchnera aphidicola RepID=KTHY_BUCBP
          Length = 212

 Score =  109 bits (273), Expect = 6e-23,   Method: Composition-based stats.
 Identities = 30/233 (12%), Positives = 73/233 (31%), Gaps = 37/233 (15%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I I G +GSGK+T+  +L N L        I +                   P    
Sbjct: 4   GKFIVIEGIEGSGKTTICKTLKNILYEHGIKNVICVRDPGS-------------TPLAEK 50

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           +RS    +  K           ++   +         +     +G  +I+DRY    +  
Sbjct: 51  IRSL---LITKDKNEYMVNETELLLFYAARIQLIKNIIQPALNKGVWVISDRYFLSSLA- 106

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-KPDHQL 192
             +              ++ L         ++ ++ P +   L +  +    R K  +++
Sbjct: 107 --YQCAGRKIKEEIVLLLQSL---------FLKNFNPNITFYLDVTPEIGLNRIKNRNEI 155

Query: 193 AALQEKIAVTPQLTFNGA--------KILELDGRHPADEILQASLRAIHAALS 237
             +++          N           I++++     D++  +  + + + L+
Sbjct: 156 DRIEQNTKFFFNNVRNKYLNLIKTKPGIIKINANRKIDKVKHSCKQQMLSWLN 208


>UniRef50_D1SN75 Thymidylate kinase n=1 Tax=Methanocaldococcus sp. FS406-22
           RepID=D1SN75_9EURY
          Length = 200

 Score =  109 bits (273), Expect = 6e-23,   Method: Composition-based stats.
 Identities = 32/218 (14%), Positives = 61/218 (27%), Gaps = 47/218 (21%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G DGSGK+T +  L  +L A           S   IG +I ++            
Sbjct: 17  FIVFEGIDGSGKTTQSKLLAEKLNAFWT-----YEPSDSEIGRFIREILSGNVKVDNK-- 69

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                               +  L +  R    + +  + ++   ++ DRY    +    
Sbjct: 70  -------------------TLALLFAADRVEHTKLIKEELKK-RAVVCDRYLYSSIAYQS 109

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---KPDHQL 192
             G               ++       +      P ++  L +D +TA  R   K   + 
Sbjct: 110 VAGV----------DENFIKSINRYALE------PDIVFLLVVDIETALKRVKTKDIFEK 153

Query: 193 AALQEKIAVTPQLTFNGAKILELDGR-HPADEILQASL 229
               EK+             + +D        + +  L
Sbjct: 154 KDFLEKVQNKYLELAEEYNFIVIDTTKKSVKVVHEEIL 191


>UniRef50_B8DAU8 Thymidylate kinase n=17 Tax=Listeria RepID=KTHY_LISMH
          Length = 208

 Score =  109 bits (272), Expect = 7e-23,   Method: Composition-based stats.
 Identities = 35/234 (14%), Positives = 69/234 (29%), Gaps = 42/234 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G DGSGK+T+   L  ++                    +I      G+P    +R
Sbjct: 5   FITLEGPDGSGKTTVGTLLNQKMTEAGID--------------FIKTREPGGSPISEKVR 50

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
           +    +  +   P       V+ +    R +    +      G  ++ DR+    +    
Sbjct: 51  NIVLGIGNEEMDPKTE----VLLIAGARRQHVVETIRPALAVGKTVLCDRFMDSSLA--- 103

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL 195
           + G            +  L   E  L        P     L +  +   AR   ++   +
Sbjct: 104 YQGAGRDMDMEQVLQVN-LYAIEDTL--------PDRTYYLDVPAEVGLARIAANKGREV 154

Query: 196 QE----------KIAVTPQLTFN--GAKILELDGRHPADEILQASLRAIHAALS 237
                       K+    +   N    + + +D     +EI +  L  I   L+
Sbjct: 155 NRLDKEDITYHEKVQAGYEKVINMFPERFMRVDATKTPEEITETILADILRQLA 208


>UniRef50_D0LII3 Thymidylate kinase n=1 Tax=Haliangium ochraceum DSM 14365
           RepID=D0LII3_HALO1
          Length = 210

 Score =  109 bits (272), Expect = 8e-23,   Method: Composition-based stats.
 Identities = 41/241 (17%), Positives = 78/241 (32%), Gaps = 49/241 (20%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           +      +I + G DGSG ST T  L +  AAR  + H     S+G +G  + ++     
Sbjct: 1   MPQHRGLLIVLEGIDGSGTSTQTRLLCDAFAARGRSTHATHEPSTGPVGLLLREMLA--- 57

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYP 127
                                      +  L +  RA    R++      G L+++DR+ 
Sbjct: 58  -----------------GAHAPVDQTTLSLLYAADRADHVQREVEPALAAGKLVVSDRWY 100

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK 187
              +      G +             +               P L I L +  + A  R+
Sbjct: 101 HSSLAYQGAGGTR-----------DWVAALNRYARA------PDLTIFLEVAAEIAARRR 143

Query: 188 PDH-QLAALQEKIAVTPQLT----------FNGAKILELDGRHPADEILQASLRAIHAAL 236
            D  +   + +++ +  ++               +I  LDG  P   +    +R +  AL
Sbjct: 144 ADDGRSEEIFDRLEIQQRVAADYREVIDSLRGRERIEVLDGERPLAAVSADIVRLVEDAL 203

Query: 237 S 237
           +
Sbjct: 204 A 204


>UniRef50_A1WGM5 Thymidylate kinase n=15 Tax=Burkholderiales RepID=KTHY_VEREI
          Length = 226

 Score =  109 bits (272), Expect = 9e-23,   Method: Composition-based stats.
 Identities = 34/233 (14%), Positives = 70/233 (30%), Gaps = 36/233 (15%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           S P   I+  G DG+GKS+    L     A+                  +S+ P  G P 
Sbjct: 2   SRPGLFISFEGIDGAGKSSHVEGLAAAFRAQGRRV-------------TVSREPG-GTPL 47

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVE 130
              LR+          T         + + +  R +  + +     +G +++ DR+    
Sbjct: 48  AEKLRALLLAERMDALTES-------LLIFAARRDHLRQVIEPALARGDVVLCDRFTDST 100

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD- 189
              F + G            ++ +       ++      P L +   +  + A  R    
Sbjct: 101 ---FAYQGAGRGFDHETLSILERMTNT-AAAHKDGLLPEPELTLWFDLAPELAAERMAGA 156

Query: 190 -HQLAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAI 232
            H+    + +     +    G          +I+ +D       + Q    A+
Sbjct: 157 AHRPDRFEAQPVEFFRRVARGYADRAAAAPRRIVRIDAAQECHRVRQQLRDAL 209


>UniRef50_A4IJA6 Thymidylate kinase n=103 Tax=Bacteria RepID=KTHY_GEOTN
          Length = 225

 Score =  109 bits (271), Expect = 9e-23,   Method: Composition-based stats.
 Identities = 32/236 (13%), Positives = 75/236 (31%), Gaps = 44/236 (18%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
               +  G +G+GK+T+   L + L  R                  +++ P  G      
Sbjct: 3   GYFFSFEGPEGAGKTTMIGKLESFLRERG-------------FDVMVTREPG-GVRIAEA 48

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           +R+              +     +   +  R +   K++   + G +++ DR+    +  
Sbjct: 49  IRALIL----NREYTEMDGRTEALLYAAARRQHLLEKIVPALEAGRVVLCDRFVDSSLAY 104

Query: 134 FRF-DGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQL 192
             F  G  + +    N +              +  Y+P L +   ID Q    R   ++ 
Sbjct: 105 QGFARGLGVEEVWKINEFA-------------IDGYMPSLTVYFDIDPQIGLERIRQNRE 151

Query: 193 AALQE----------KIAVTPQLTFNG--AKILELDGRHPADEILQASLRAIHAAL 236
             +            K+    +        +I+ +D   P D++   ++  + + L
Sbjct: 152 REVNRLDLETLSFHDKVREGYRKLAKRFAERIVVIDASRPLDDVFSETVATVLSRL 207


>UniRef50_C5CHP2 Thymidylate kinase n=1 Tax=Kosmotoga olearia TBF 19.5.1
           RepID=KTHY_KOSOT
          Length = 208

 Score =  109 bits (271), Expect = 9e-23,   Method: Composition-based stats.
 Identities = 35/226 (15%), Positives = 66/226 (29%), Gaps = 43/226 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I+  G DGSGKST  A     L                + GE I ++ +          
Sbjct: 2   FISFEGIDGSGKSTQVALFREYLERNSMEYVFIREPGGTQAGEDIREILLHNEY------ 55

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
                                + L    RA   R+ ++   ++  L++ DR+    V   
Sbjct: 56  --------------KLFPETELLLFMASRAQIVREVIIPALKKKKLVLADRFLDSSVAYQ 101

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD---HQ 191
            +         G    I+M+               P L + + +    A  R      H 
Sbjct: 102 GY---------GRGLSIQMVTTLNEF---STGGVTPHLTLFIDVPVDVAVKRMRREMKHD 149

Query: 192 LAALQE-------KIAVTPQLTFNGAKILELDGRHPADEILQASLR 230
              ++        +         +  +IL +DG    ++I +  ++
Sbjct: 150 KIEMESLDFFKRVRQGYLELAKRDPKRILVIDGTMSVEKIHEQVVK 195


>UniRef50_C3K0M9 Thymidylate kinase n=7 Tax=Gammaproteobacteria RepID=KTHY_PSEFS
          Length = 210

 Score =  109 bits (271), Expect = 9e-23,   Method: Composition-based stats.
 Identities = 33/234 (14%), Positives = 67/234 (28%), Gaps = 40/234 (17%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
               I + G +G+GKST    L   L +                   +++ P  G P   
Sbjct: 2   TGLFITLEGPEGAGKSTNRDYLAERLRSEGIEVV-------------LTREPG-GTPLAE 47

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVP 132
            +R       E+   P       ++ + +    +    +     +G ++I DR+      
Sbjct: 48  RIREVLLAPGEEQMNPDTE----LLLVFAARAQHLAEVIRPALARGAVVICDRFTDST-- 101

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-KPDHQ 191
            + + G            +  +   E  +        P L +   +  +   AR     +
Sbjct: 102 -YAYQGGG------RGLSLARIATLETFV---QGDLRPDLTLVFDLPVEVGLARASARGR 151

Query: 192 LAALQ---------EKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
           L   +          + A   +      +   LD   P   + QA    +   L
Sbjct: 152 LDRFELEGQAFFDAVRTAFLTRAAAEPERYYLLDAAQPLAHVQQAIDALLPTLL 205


>UniRef50_C3CT99 Thymidylate kinase n=1 Tax=Bacillus thuringiensis Bt407
           RepID=C3CT99_BACTU
          Length = 206

 Score =  109 bits (271), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 41/237 (17%), Positives = 71/237 (29%), Gaps = 45/237 (18%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
           T    ++I G +GSGKS L   L   L  +                E ++     G    
Sbjct: 3   TRGLFVSIEGGEGSGKSALIQGLSLYLEEQG--------------MECLTSREPGGVKVA 48

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEV 131
             +R       E       +     +   S  R +   K+     +G ++I DR+    +
Sbjct: 49  EEIR-------ELIMENEMDAITEALLFASARREHFKNKISPALTEGKIVICDRFVDSSI 101

Query: 132 PGFRF-DGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP-- 188
               +  G  +      N                    +P L + L ++   A  R    
Sbjct: 102 VYQGYVQGIGMDNVLSINSQA------------LEGLVMPHLTLYLDVEPTIALNRIAQN 149

Query: 189 -------DHQLAALQEKIAVTPQLTFNG--AKILELDGRHPADEILQASLRAIHAAL 236
                  D +     +K+     L       +I ++D     DE+LQ S+  I   L
Sbjct: 150 NRETNRFDEKSIEFHKKVREGYLLIEEKHSNRIKKVDASLSKDEVLQQSIEYIKNIL 206


>UniRef50_A8MB58 Probable thymidylate kinase n=3 Tax=Thermoproteaceae
           RepID=KTHY_CALMQ
          Length = 205

 Score =  109 bits (271), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 35/227 (15%), Positives = 70/227 (30%), Gaps = 44/227 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            + + G DG GKST+     +EL  R    +     S   IG +I +             
Sbjct: 4   FVDVEGIDGVGKSTVIRLTADELRRRGYLVYTTSEPSDSPIGLFIRR------------- 50

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKF-RKMLCKSQQGFLLITDRYPQVEVPGF 134
                      +        +  L +  R   + R +  K ++G+++IT+RY +  V   
Sbjct: 51  -------SILESNLEVEPMALALLFAADRVIHYNRVIKPKVKEGYIVITERYIESSVAYQ 103

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
              G            ++ + +    + +      P L+I L     T  +R  +  +  
Sbjct: 104 GSQGV----------PVEWIIEVNSMVAE------PDLVIVLNAPLNTVASRLSNRGMLE 147

Query: 195 LQEK-------IAVTPQLTFNGAKILELDGRHPADEILQASLRAIHA 234
             E+       +               +D     + ++   L  I  
Sbjct: 148 YFERNTDFLRSVQEVYLRRARERNYPVIDASRVINNVVNDVLTLIED 194


>UniRef50_B1V9T6 Thymidylate kinase n=9 Tax=16SrXII (Stolbur group)
           RepID=B1V9T6_PHYAS
          Length = 215

 Score =  109 bits (271), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 32/238 (13%), Positives = 68/238 (28%), Gaps = 52/238 (21%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           ++I+  G DGSGK+TL   L      +     ++ G  S  +G+ I  L +  +      
Sbjct: 4   KLISFEGVDGSGKTTLINELKKYFENKGYQIKVFQGLGSSIVGKEIRNLFLHQSKISPKT 63

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           +   +  +   +                        ++     G+L++ DR+       F
Sbjct: 64  KYLLSLANMLQTQDEL--------------------IIPALLSGYLVLVDRWYGST---F 100

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK---PDHQ 191
            +               K++               P L   L ID +    RK    +H+
Sbjct: 101 AYQSKGNYIDYDDKITSKIINHF---------LIKPKLTFYLDIDPKIGIQRKQNQTNHK 151

Query: 192 LAALQEKIAVTPQ-----------------LTFNGAKILELDGRHPADEILQASLRAI 232
           L  ++ K     +                           ++      + L   ++ +
Sbjct: 152 LDLIERKPLNYFENVRKHYLNQHKYCNDANYNHKNCNHFLINATKSQKDNLNQIMKIL 209


>UniRef50_A9AV71 Thymidylate kinase n=6 Tax=Chloroflexi (class) RepID=KTHY_HERA2
          Length = 236

 Score =  109 bits (271), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 30/189 (15%), Positives = 51/189 (26%), Gaps = 32/189 (16%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G +GSGKST    L + L        +        I + + +L + G        
Sbjct: 4   FITFEGPEGSGKSTQARYLKDYLQQAGYPVILTREPGGTPISDAVRRLVLDGQW------ 57

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
                                  L +  RA    + +L   + G +++ DRY        
Sbjct: 58  -------------TAMEPTTETLLFAAARAQLVGEVILPYLKLGGIVLCDRYADSTFAHQ 104

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
            +         G    +  LR+             P L   L +  +    RK   +   
Sbjct: 105 GY---------GLGRNLTELREITRFA---TGGLQPDLTFFLDLPVEQGLQRKRKQRDDF 152

Query: 195 LQEKIAVTP 203
            +      P
Sbjct: 153 RESSQLALP 161


>UniRef50_B1YGD3 Thymidylate kinase n=2 Tax=Bacillales RepID=KTHY_EXIS2
          Length = 212

 Score =  109 bits (271), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 36/235 (15%), Positives = 68/235 (28%), Gaps = 42/235 (17%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
               I + G DG+GK+T    L + L A                   +++ P  G   G 
Sbjct: 2   TGTFITVEGPDGAGKTTQLQLLADRLTAEGYEIV-------------MTREPG-GTRIGN 47

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEV 131
            +RS   +                I L +  RA    + +      G +++ DR+    +
Sbjct: 48  EIRSLILNPD-----FQEMDEMTEILLYAASRAQHVNELIRPALAAGKIVLCDRFIDASI 102

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQ 191
               + G  L  T      I           Q      P       +    +  R  D  
Sbjct: 103 A---YQGYGLGYTIEQVRSIN---------QQATNHLTPDRTYLFDLTVSESKQRMMDRG 150

Query: 192 -LAALQEKIAVTPQLTFNG---------AKILELDGRHPADEILQASLRAIHAAL 236
            L  ++++     Q  ++G          +I  +D     + +     + +   L
Sbjct: 151 ALDRIEQRDDAFRQRVYDGFMTLAVQEPERIQLVDANQSIESLQTELCKDVLTYL 205


>UniRef50_Q1C6N6 Thymidylate kinase n=40 Tax=Enterobacteriaceae RepID=KTHY_YERPA
          Length = 212

 Score =  108 bits (270), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 37/232 (15%), Positives = 77/232 (33%), Gaps = 37/232 (15%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           + I I G +G+GK+T   ++V  L A+   + ++            ++ P  G P    L
Sbjct: 4   KFIVIEGLEGAGKTTTRDTVVAVLRAQGINDIVF------------TREPG-GTPLAEKL 50

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           R       +          A V+ L +         +     +G  ++ DR    ++   
Sbjct: 51  RDLIKQGIDGEVLTDK---AEVLMLYAARVQLVENVIKPALARGSWVVGDR---HDLSSQ 104

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA--------- 185
            + G      +     ++            +  + P L + L +      A         
Sbjct: 105 AYQGGGRGIDSQLMASLR---------DTVLGEFRPDLTLYLDLPPAVGLARARARGELD 155

Query: 186 RKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
           R     LA  +   A   +L  + A I  +D   P +++  +  +A+   L+
Sbjct: 156 RIEQESLAFFERTRARYLELAASDASIKTIDASQPIEQVSASISQALAQWLT 207


>UniRef50_C4DQR2 Thymidylate kinase n=1 Tax=Stackebrandtia nassauensis DSM 44728
           RepID=C4DQR2_9ACTO
          Length = 204

 Score =  108 bits (270), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 40/224 (17%), Positives = 64/224 (28%), Gaps = 41/224 (18%)

Query: 17  IAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLRS 76
           IA+VG DG+GK+T    L   L          +  S                  GR +  
Sbjct: 10  IALVGIDGAGKTTQARWLKRWLTQLGHPVRYRMVAS------------------GRRVLG 51

Query: 77  KAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFRF 136
             A    +P +       + I   +  R +           G +LI DRY   +    R 
Sbjct: 52  NTARRLGRPDSVALLGPGMAIRAETLLRYWNLTVG----NGGGILIADRYAVCQYARTRV 107

Query: 137 DGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAAL- 195
             P+L             R+             P L + L +  +TA  R     +    
Sbjct: 108 VYPRLEP---------WARRL------LGRVPPPDLTLYLDVAPETAHLRVKTRGIDEEP 152

Query: 196 ---QEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                 +    +     A    +D     +EI +     +  AL
Sbjct: 153 VDSLAAMDSAYRSLPEFASFAIVDANRDPEEIAETIRDEVRTAL 196


>UniRef50_A6TJF7 dTMP kinase n=2 Tax=Alkaliphilus RepID=A6TJF7_ALKMQ
          Length = 211

 Score =  108 bits (270), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 36/234 (15%), Positives = 64/234 (27%), Gaps = 42/234 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
              I+  G DG+GKST      +    R                  +++ P  G      
Sbjct: 4   GLFISFEGVDGAGKSTQIHYAKDFFEERGYKV-------------SLTREPG-GTRISEI 49

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVP 132
           +R           T           L +  RA    + +L    +G +++ DR+      
Sbjct: 50  IREAILD-----RTHQEMTHRTEALLYAASRAQHVEEFILPALAEGRVVLCDRFVDSS-- 102

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-----K 187
              + G       G       +R              P L I   I  Q +  R     K
Sbjct: 103 -MVYQG------RGRGLGFDAVRNINQFA---TGGLEPDLTIFFNIHPQVSLGRINVKEK 152

Query: 188 PDH-QLAALQEKIAVTPQLT----FNGAKILELDGRHPADEILQASLRAIHAAL 236
            D  +   +     V          N ++I  ++     ++I     + +   L
Sbjct: 153 GDRLEQEKMAFHYTVYESYHDLAQMNSSRIKVIEANQEVEKIKSEVEKIMTNLL 206


>UniRef50_C8W7S9 Thymidylate kinase n=3 Tax=Atopobium RepID=C8W7S9_ATOPD
          Length = 219

 Score =  108 bits (270), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 31/238 (13%), Positives = 64/238 (26%), Gaps = 41/238 (17%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
             ++    I + G DG GKST  + L  +L A                     + P  G 
Sbjct: 5   TRTSQGLFITLEGVDGCGKSTQASLLREDLKAL-------------NFDVVFVREPG-GT 50

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYP 127
                +R                     + L    RA    + +      G +++ DR+ 
Sbjct: 51  AISEQIRDVVL-----NPKNGAMCDECELLLYEASRAQLVEEVIRPALASGKVVLCDRFY 105

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK 187
                             G      ++          ++   P   +   ++   A AR 
Sbjct: 106 DSTYAYQA---------AGRGLDTDLVHHANRLGSCGVS---PDRTLVFMLEPTVAHARA 153

Query: 188 PDHQLAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAAL 236
             +    L+ +     +  F G          ++  +D     DE+   + + +   +
Sbjct: 154 TQNDTDRLEAEGVAFQERVFAGYKQLLQDEPERVKAIDADGSIDEVRTRTRQLLADLI 211


>UniRef50_C6DKS8 Thymidylate kinase n=188 Tax=Gammaproteobacteria RepID=KTHY_PECCP
          Length = 219

 Score =  108 bits (269), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 32/223 (14%), Positives = 64/223 (28%), Gaps = 37/223 (16%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           + I I G +G+GK+T    +V  L +    E ++  +  G       +  +        +
Sbjct: 4   KFIVIEGLEGAGKTTARHIVVETLRSHGVKEVVFTREPGGTPLAEKLRELIKQGMTDEKV 63

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
             K                A V+ L +         +      G  +I DR    ++   
Sbjct: 64  TDK----------------AEVLMLYAARVQLVDNVIKPALANGQWVIGDR---HDLSSQ 104

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA--------- 185
            + G             ++LR     +   +  + P L + L +                
Sbjct: 105 AYQGGG------RGIDQQLLRSLRDTV---LGDFRPDLTLYLDLPPAIGLQRARARGELD 155

Query: 186 RKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQAS 228
           R     LA  +   +   +L      IL +D     + +    
Sbjct: 156 RIEQESLAFFERTRSRYQELAAEDDSILTIDASQSIEAVSADI 198


>UniRef50_A9NEH3 Thymidylate kinase n=1 Tax=Acholeplasma laidlawii PG-8A
           RepID=KTHY_ACHLI
          Length = 201

 Score =  108 bits (269), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 40/234 (17%), Positives = 72/234 (30%), Gaps = 47/234 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G +GSGK+TL   L + L  +                   ++ P  G+     +R
Sbjct: 2   FITFEGGEGSGKTTLIEKLKHTLLEKKYDV-------------LTTREPG-GSKVAEKIR 47

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
           S                      L +  RA    + ++       +++ DRY        
Sbjct: 48  SVLLDNKNTE-----ITAHTEALLFAASRAQHLDEVIIPNLD--KVILCDRYIDSSYAYQ 100

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD---HQ 191
            F         G N  ++ ++       +++    P L   + +D +T   R      H+
Sbjct: 101 AF---------GRNLGMEFVQSINSYALKYL----PDLTFYIDLDPKTGIDRVKKNRLHK 147

Query: 192 LAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAAL 236
              L  ++    Q    G          +I+ +DG    D I Q  +  I   L
Sbjct: 148 TDRLDMEVQTFHQKVREGYIRISEMFKERIVVIDGNQSIDAIYQIIMDNILKRL 201


>UniRef50_Q1ILM2 Thymidylate kinase n=1 Tax=Candidatus Koribacter versatilis
           Ellin345 RepID=Q1ILM2_ACIBL
          Length = 217

 Score =  108 bits (269), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 29/246 (11%), Positives = 67/246 (27%), Gaps = 48/246 (19%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           + S   + +   G DG GKST    L   L                      ++ P  G 
Sbjct: 1   MVSARGKFLTFEGLDGCGKSTQMEMLAEVLRRDGIDVVT-------------TREPG-GT 46

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQ 128
           P G  +RS       +      +  A +  + +    +    +    + G  ++ DR+  
Sbjct: 47  PTGEKIRSVILDSKTRF----LHPMAELALMFAARAQHIAEIVQPSLEAGRWVLCDRFTD 102

Query: 129 VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAF---- 184
                  + G      +     +  +               P + I +  D + +     
Sbjct: 103 SS---EAYQGGGRQMGSQLILDMHKIV---------CGDLWPEMTILMDSDPEASVARAR 150

Query: 185 ------------ARKPDHQLAALQEKIAVTP--QLTFNGAKILELDGRHPADEILQASLR 230
                         + + +     +++             ++ ++D R   D      +R
Sbjct: 151 RRNRANATDGVDENRFEREKIEFFQRVRDAYNAIADREPQRVYKVDARRSKDVTHPEIVR 210

Query: 231 AIHAAL 236
           A+   +
Sbjct: 211 AVRERM 216


>UniRef50_A0Z288 Thymidylate kinase n=1 Tax=marine gamma proteobacterium HTCC2080
           RepID=A0Z288_9GAMM
          Length = 215

 Score =  108 bits (269), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 33/237 (13%), Positives = 70/237 (29%), Gaps = 40/237 (16%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           +   + I + G +G GK+T    +   L                 I   +++ P  G   
Sbjct: 5   THTAKFITVEGGEGVGKTTQLRLIEARLREAG-------------IPLLVTREPG-GTEL 50

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVE 130
           G  LR                  A ++ + +    +    +    Q+G  ++ DR+    
Sbjct: 51  GEQLRQLLLQ----KEGLAPTPMAELLMVFAARAQHVDTVIAPALQRGEWVLCDRFTD-- 104

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-KPD 189
              F + G       G    +  L    +          P L I L +D +    R +  
Sbjct: 105 -ASFAYQGFGRGLPLGAIQQLAELAHPHIN---------PNLSILLDVDPEVGLERARAR 154

Query: 190 HQLAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAALS 237
            +L   + +     +   NG          +   +D     +++ Q     +   ++
Sbjct: 155 GELDRFELETIPFFEAVRNGYLQRVKLEPHRWRVIDAGVALEQVEQQLGDCLKEWIA 211


>UniRef50_UPI0000DB6E10 PREDICTED: similar to deoxythymidylate kinase (thymidylate kinase)
           n=2 Tax=Apocrita RepID=UPI0000DB6E10
          Length = 192

 Score =  108 bits (269), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 36/226 (15%), Positives = 65/226 (28%), Gaps = 40/226 (17%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           ++     +I + GCD +GKST    L+  L        ++          + ++   IG 
Sbjct: 1   MSIRRGALIVLEGCDRAGKSTQAKMLITALNNLNIPVELH---------SFPNRTTTIGE 51

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQ 128
               +L  K                  +  L S  R     ++L    +G  LI DR   
Sbjct: 52  IINNFLTKKTE-----------LPPETIHLLFSANRWECKDEILKTLYKGTTLIIDR--- 97

Query: 129 VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK- 187
                                 +   R+ +  L        P L+I L I +++   R  
Sbjct: 98  ------YAASGAAYTAATTGKNLNWCREPDSGL------PSPDLVIYLSISKKSQSLRSN 145

Query: 188 ---PDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLR 230
                 +    QE +A   +   +      ++       I    L 
Sbjct: 146 WGDERFENVEFQELVASNYEKLIDK-TWYVINADDDKSVIHSQILE 190


>UniRef50_Q6F0E1 Thymidylate kinase n=1 Tax=Mesoplasma florum RepID=KTHY_MESFL
          Length = 211

 Score =  108 bits (268), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 33/232 (14%), Positives = 76/232 (32%), Gaps = 41/232 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I I G DGSGK+T    +   L                     +++ P  G P    +R
Sbjct: 2   FITIEGMDGSGKTTALQRVKQYLEDL-------------NYKVVMTREPG-GLPLSEKIR 47

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                +               +  ++  + +  + +    ++G+++I+DR+         
Sbjct: 48  ----ELILNKDGVGMEPWTEALLFIAARKEHLEKVIKPYLKKGYIVISDRFMDSTTA--- 100

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-----KPDH 190
           + G            +  L + +  + +    +LP L +   +  + A  R     +  +
Sbjct: 101 YQGG------ARGLGVDYLNELQKNILE---GFLPDLTLYFELSFEDAEKRLSARPEEKN 151

Query: 191 QLAALQEKIAVTPQLTF------NGAKILELDGRHPADEILQASLRAIHAAL 236
           +L     K     +L F         +I  +D     +E+ + + + I   +
Sbjct: 152 RLDEEGRKFKEAVKLAFEELVVKEPNRITVIDASKSPEEVFEETKKVILEKI 203


>UniRef50_A4ECY1 Putative uncharacterized protein n=3 Tax=Collinsella
           RepID=A4ECY1_9ACTN
          Length = 227

 Score =  108 bits (268), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 33/231 (14%), Positives = 61/231 (26%), Gaps = 42/231 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G DG+GKST    L   L                            G      +R
Sbjct: 10  FITLEGVDGAGKSTQARLLARALELAGYQVVSLREPG--------------GTAISEKIR 55

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
           +                    + L    RA    + +      G +++ DR+        
Sbjct: 56  ALLLDPANTAMGDTCE-----LLLYEAARAQLVHEVIAPALAAGKVVLCDRFYDSTTCYQ 110

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQ-LA 193
            F               +M+R         +A   P L +   I  + A  R  D     
Sbjct: 111 AF---------ADGLDRQMVRDANNLA---VAGTHPALTLVYHITPEQAALRMADRGAAD 158

Query: 194 ALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAA 235
            ++ K     +  + G          ++  +D     +E+   ++  + A 
Sbjct: 159 RMEAKGMAFQERVYQGFCAIAAEEPNRVKLIDATATIEEVFAKTVEQVRAY 209


>UniRef50_A5CPG8 Thymidylate kinase n=28 Tax=Bacteria RepID=KTHY_CLAM3
          Length = 211

 Score =  108 bits (268), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 39/237 (16%), Positives = 68/237 (28%), Gaps = 44/237 (18%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
               I + G DG GKST +A L   L        +        +G  I ++ +       
Sbjct: 2   TGVFITLEGGDGVGKSTQSALLRGWLEDEGHEVVVTREPGGSELGVEIREIVLHRR---- 57

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEV 131
                                     L +  RA+     +     +G +++ DRY    V
Sbjct: 58  ----------------GHIAPRAEALLYAADRAHHVETVVRPALDRGAVVLQDRYLDSSV 101

Query: 132 PGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR--KPD 189
               + G       G    + +               LP L + L +D+  A  R     
Sbjct: 102 A---YQGAGRVLDAGEIRELSLWAA---------QGLLPDLTVLLDLDQAAARVRLDAAR 149

Query: 190 HQLAALQEKIAVTPQLTF---------NGAKILELDGRHPADEILQASLRAIHAALS 237
            +   L+ + A   +               + L +D   P +EI  A      A ++
Sbjct: 150 TRFDRLESERADFHERVRQAFLGLAGAEPERFLVVDAARPREEIAAAIRTRAQALIA 206


>UniRef50_C9RR73 Thymidylate kinase n=1 Tax=Fibrobacter succinogenes subsp.
           succinogenes S85 RepID=C9RR73_FIBSS
          Length = 210

 Score =  108 bits (268), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 36/238 (15%), Positives = 65/238 (27%), Gaps = 42/238 (17%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
            T  +  ++ G DGSGKST    LV  L +                 + +      GA  
Sbjct: 2   KTAKKFFSLEGIDGSGKSTQIDMLVRVLESEGH--------------KVVRLREPGGAKI 47

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQV 129
              +R         P+          + L +  RA    + +      G ++I DR+   
Sbjct: 48  SERIRELLLD----PAFKGIMADDTELLLYNAARAQVIHEIIKPALDAGNIVIADRFAWS 103

Query: 130 EVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP- 188
                 +                   + +           P L + L +  + +  R   
Sbjct: 104 TFAYQGY---------ARGLGAD---KVQRLTELTCGGCFPELTVVLDLTVEASRKRMAI 151

Query: 189 --------DHQLAALQEKIAVTPQLTFNGAKIL--ELDGRHPADEILQASLRAIHAAL 236
                   + + A   E++                 ++     DE+ Q  L  I A L
Sbjct: 152 RGGAPDRLESEKAEFFERVREGYLAAGRDYSDCVSVVNADRTPDEVHQDVLSLIKAKL 209


>UniRef50_C4K9M9 Thymidylate kinase n=8 Tax=Betaproteobacteria RepID=C4K9M9_THASP
          Length = 233

 Score =  108 bits (268), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 31/233 (13%), Positives = 62/233 (26%), Gaps = 44/233 (18%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            R I   G DG+GKS+  A+               +       G  + Q    G      
Sbjct: 31  GRFITFEGIDGAGKSSQIAA---------------VVALLQAAGRDVDQTREPGGT---- 71

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
             +    + E     P ++    + + +  R +   ++      G  ++ DR+       
Sbjct: 72  --ALGERLRELLLHEPMHLETEAMLMFAARREHLAARIEPALAAGRWVVCDRFSDATFAY 129

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP----- 188
               G  L +              +           P L +   +D   A AR       
Sbjct: 130 QV-GGRGLDRAK-----------FDALEAWVHPGLQPDLTLVFDLDPALAAARVASTGVD 177

Query: 189 ----DHQLAALQEKIA--VTPQLTFNGAKILELDGRHPADEILQASLRAIHAA 235
               + +     E++      +      +I  +D     + I     R +   
Sbjct: 178 PDRFEREQRDFFERVRAAYLERARLAPLRICVIDAARSPEAIRADIERVVRER 230


>UniRef50_A0Q893 Thymidylate kinase n=19 Tax=Francisella RepID=KTHY_FRATN
          Length = 209

 Score =  108 bits (268), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 32/232 (13%), Positives = 67/232 (28%), Gaps = 38/232 (16%)

Query: 15  RVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYL 74
           + I I G DG+GKST  + +   L                 +    ++ P  G      L
Sbjct: 4   KFIVIEGLDGAGKSTAISFVRKYLEK-------------NNLAAIYTREPG-GTKIAEEL 49

Query: 75  RSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
           R+   H          +  + ++ + +    +    +    ++G  +++DR+    +   
Sbjct: 50  RNLVLH---NKYDEEIHSDSELLMIYAGRVQHYRNLIAPALEKGINVVSDRFYWSSMA-- 104

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA--------- 185
            + G            +            ++    P L+I L ID               
Sbjct: 105 -YQGGGRGVELSKIRALN---------DNFLNGCEPDLVIYLDIDPILGLQRAQKVGSPD 154

Query: 186 RKPDHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
           R     L        V   L  +    +E+D      E+ +     +    +
Sbjct: 155 RIEKAGLEFFNRTRNVFKDLVKDSDNAIEIDAAKSIQEVEKQIYLILDKHFN 206


>UniRef50_B2UN87 Thymidylate kinase n=1 Tax=Akkermansia muciniphila ATCC BAA-835
           RepID=KTHY_AKKM8
          Length = 206

 Score =  108 bits (268), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 38/232 (16%), Positives = 64/232 (27%), Gaps = 41/232 (17%)

Query: 6   MSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPV 65
           MS       R+I   G DG+GKST    L   L  +          + GR G  +    V
Sbjct: 1   MSFTGERKGRLIVFEGIDGTGKSTHIGHLRKYLEEKELEVVQSFEPTRGRWGRMLRDSAV 60

Query: 66  IGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDR 125
            G                       ++   V   L   R +    +     +G  ++ DR
Sbjct: 61  TGR---------------------LSVEEEVALFLKDRREHVKMLIAPALARGAWVLLDR 99

Query: 126 YPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFA 185
           Y    +      G         N                  + +P  ++ L I    A  
Sbjct: 100 YYLSMMAYQGARGIDPEVIRAANE---------------EFAPVPDAVVWLDIPVSVALE 144

Query: 186 RKPDHQLAALQEKIAVTPQ-----LTFNGAKILELDGRHPADEILQASLRAI 232
           R  +       E  A          + +   +L +D     +E+     +A+
Sbjct: 145 RIGNRGERDAFETEAGLAACRSVFASVHAPWMLRIDADAGKEEVAARVRKAL 196


>UniRef50_A9QS84 Thymidylate kinase n=3 Tax=Bacilli RepID=A9QS84_LACLK
          Length = 199

 Score =  108 bits (268), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 32/232 (13%), Positives = 62/232 (26%), Gaps = 50/232 (21%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I   G DGSGK+T    L      +     ++  +          +             
Sbjct: 5   LIVFEGLDGSGKTTQIDMLHQWFENK--KLEVFTTKQPTDYYRNDKR------------- 49

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWR-AYKFRKMLCKSQQGFLLITDRYPQVEVPGF 134
                V +            +  L +  R      ++  K  +   +I DRY    +  F
Sbjct: 50  -----VRDYLDNGIAPNMYSIALLAAADRTYQISSEIFPKISE-SNIICDRYLYSSLAFF 103

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAA 194
           +  G    +    N                    +P + + L +  + A  R        
Sbjct: 104 KARGIDYKEILMINK----------------GVPIPDVTVFLDVPPERALERVRQRDGED 147

Query: 195 LQEKIAVTPQLTFNGAK----------ILELDGRHPADEILQASLRAIHAAL 236
           +  K     +L FN  +           L +D     D++ Q     +   +
Sbjct: 148 I--KYEEKNELVFNQVRQNFLDVLPKNALIVDSTLGIDKVHQIITNFVSEVM 197


>UniRef50_C6XJM4 Thymidylate kinase n=1 Tax=Hirschia baltica ATCC 49814
           RepID=C6XJM4_HIRBI
          Length = 211

 Score =  107 bits (267), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 33/230 (14%), Positives = 71/230 (30%), Gaps = 40/230 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            R + + G +G GKSTL ++L  +L                 I   +++ P  G+  G  
Sbjct: 4   GRFVTLEGGEGVGKSTLASNLQKKLLEL-------------DIKCLLTREPG-GSLGGEA 49

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           +R+   +        P   T   +   +    +    +     +G  +I DR+       
Sbjct: 50  IRNIVLNPPHHQDWSPLTQT---LLFFAARCDHLENVIKPALLRGEWVICDRFTDSTRAY 106

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQ-- 191
                        G     ++   +  +        P L + L +  + +  R+ +    
Sbjct: 107 QA---------VAGGVDDHVVSTLDQLVVNEQQ---PDLTLLLDMPLEVSAKRRIERNGP 154

Query: 192 LAALQE---------KIAVTPQLTFNGAKILELDGRHPADEILQASLRAI 232
             A ++         + A          +   LD  +  D++   +L  I
Sbjct: 155 QDAFEKLPQSFHENVRQAFLEIADRYKDRCYVLDASNSVDQVTAEALELI 204


>UniRef50_Q01Q29 Thymidylate kinase n=1 Tax=Candidatus Solibacter usitatus Ellin6076
           RepID=Q01Q29_SOLUE
          Length = 224

 Score =  107 bits (267), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 40/242 (16%), Positives = 69/242 (28%), Gaps = 47/242 (19%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
             P   I   G DGSGK+T    L   L     T        +   G         G P 
Sbjct: 14  KLPGIFITFEGMDGSGKTTQMHRLAERLRGMGRTV-----LETAEPG---------GPPI 59

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQV 129
            + +R        +            I L    RA    + +     +G +++ DR+   
Sbjct: 60  AQKIRRIVLDAANQE-----LSPTAEILLYFASRAQNVDQWIQPALARGEIVLADRFTDS 114

Query: 130 EVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR--- 186
            +    + G       G       +   +    +      P L I + +D + +  R   
Sbjct: 115 SL---VYQG------IGRGLGADTVVALDRIACR---GLKPDLTILVDVDAEASLTRARA 162

Query: 187 ----------KPDHQLAALQEKI--AVTPQLTFNGAKILELDGRHPADEILQASLRAIHA 234
                     + D Q      K+  A          ++   +GR   DEI +     + A
Sbjct: 163 RNLAQPHCETRMDDQALEFHLKVHAAYHALAAAEPERVKVANGRAGMDEIEREIWSIVSA 222

Query: 235 AL 236
            +
Sbjct: 223 HV 224


>UniRef50_D1Y158 dTMP kinase n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y158_9BACT
          Length = 201

 Score =  107 bits (267), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 39/231 (16%), Positives = 61/231 (26%), Gaps = 45/231 (19%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I I G DGSGKST    L   L                  G+ +  L + G        
Sbjct: 2   FITIEGIDGSGKSTQARRLAARLRREGKKVTETHEPGDWPHGDILRALLLNGRLRH---- 57

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
                                I L    R     + +     QG  ++ DRY        
Sbjct: 58  -----------------PMTEIMLFVADRCEHVAQVIQPALDQGEFVVCDRYNDSTRAYQ 100

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDH-QLA 193
            +         G      +L      L +W     P L + L +  + A  R        
Sbjct: 101 CW---------GRGLKEDILES----LIKWCGIPEPDLTVWLDLPVEEARKRMAGRGGSD 147

Query: 194 ALQEKIAVTPQ---------LTFNGAKILELDGRHPADEILQASLRAIHAA 235
            ++ +     +            NG++   +D R   DEI +     +   
Sbjct: 148 RIEGEDLKFHEAVARGFKELAERNGSRFFRVDARAGEDEIEETIFSELKRR 198


>UniRef50_B3QXL1 dTMP kinase n=1 Tax=Chloroherpeton thalassium ATCC 35110
           RepID=B3QXL1_CHLT3
          Length = 226

 Score =  107 bits (267), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 40/242 (16%), Positives = 67/242 (27%), Gaps = 54/242 (22%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I   G DGSGKST    L + L +R                         G P    +R
Sbjct: 9   LITFEGIDGSGKSTQIKLLKDFLQSRGFEVLSLREPG--------------GVPVAEQIR 54

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQVEVPGF 134
           +       +            + L S  RA   +  ++   +Q  +++ DR+    V   
Sbjct: 55  AILLENKNE------INPIAELLLFSASRAALVQAVIIPALEQRQVVVLDRFYDSTVAYQ 108

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQ--- 191
            +         G    ++ + Q            LP L     +  + A  RK   +   
Sbjct: 109 GY---------GRGISLERIHQINEIAS---FGLLPNLTFYFDLQPEDALLRKFSEKSLP 156

Query: 192 ---------LAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIH 233
                    L  ++       Q    G          +  E+D      EI Q  +  I 
Sbjct: 157 LSFKDNEIPLDRMERAGLEFFQRVRTGYKELVQTAPERFYEIDALCSISEIHQKVVERIK 216

Query: 234 AA 235
             
Sbjct: 217 TH 218


>UniRef50_Q8UFA0 Thymidylate kinase n=1 Tax=Agrobacterium tumefaciens str. C58
           RepID=KTHY_AGRT5
          Length = 224

 Score =  107 bits (267), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 31/242 (12%), Positives = 69/242 (28%), Gaps = 44/242 (18%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           +       I+  G +G+GKST   +L   L  R     +          E +  + + GA
Sbjct: 1   MAEKTGLFISFEGGEGAGKSTQIRTLAEALRGRGFEVVVTREPGGSPGAEAVRHVILSGA 60

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQ 128
                +R +A                  I   +    +    +     +G +++ DR+  
Sbjct: 61  AESFGVRMEA------------------ILFAAARNDHVEEVIRPALARGEIVLCDRFLD 102

Query: 129 VEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP 188
                  + G        GN     +   +      +   +P L +   I  +   AR  
Sbjct: 103 SS---RVYQGTT------GNLEPDFIETLQRIAIDGV---VPELTLIFDIAAEKGLARAR 150

Query: 189 DH----------QLAALQ----EKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHA 234
                       +   ++     + A          +   ++   P D++ +  +  +  
Sbjct: 151 KRADEGATPDRFEKEEIETHEKRREAYLDIALAEPRRCRIVNADQPEDKVTEDVMSFVEP 210

Query: 235 AL 236
            L
Sbjct: 211 LL 212


>UniRef50_A6T7F8 Thymidylate kinase n=62 Tax=Gammaproteobacteria RepID=KTHY_KLEP7
          Length = 213

 Score =  107 bits (267), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 33/230 (14%), Positives = 73/230 (31%), Gaps = 35/230 (15%)

Query: 17  IAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLRS 76
           I I G +G+GK+T    +V  L +    + ++            ++ P  G      LRS
Sbjct: 6   IVIEGLEGAGKTTARQLVVETLQSAGIHDMVF------------TREPG-GTILAEKLRS 52

Query: 77  KAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFRF 136
               +         +   +++   +         +     +G  +I DR    ++    +
Sbjct: 53  LVLDIQSTGDEVINDKAEVLM-FYAARVQLVETVIKPALARGQWVIGDR---HDLSTQAY 108

Query: 137 DGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-KPDHQLAAL 195
            G              ML      +   +  + P L + L +  +    R +   +L  +
Sbjct: 109 QGGG------RGIDRTMLATLRDAV---LGDFRPNLTLYLDVTPEVGLQRARARGELDRI 159

Query: 196 QEK--------IAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
           +++         A   +L      I  +D   P D + +     I   ++
Sbjct: 160 EQESMNFFNRTRARYLELAAADPSIRTVDATQPLDAVARDIRATIAQWMA 209


>UniRef50_Q1ICY2 Thymidylate kinase n=23 Tax=Gammaproteobacteria RepID=KTHY_PSEE4
          Length = 210

 Score =  107 bits (267), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 30/234 (12%), Positives = 70/234 (29%), Gaps = 40/234 (17%)

Query: 13  PVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGR 72
               I + G +G+GKST    L   L  +                  +++ P  G P   
Sbjct: 2   SGLFITLEGPEGAGKSTNREYLAARLREQGVDVV-------------MTREPG-GTPLAE 47

Query: 73  YLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVP 132
            +R       E+       +   ++ + +    +  + +     +G +++ DR+      
Sbjct: 48  RIRELLLAPSEE----AMAVDTELLLMFAARAQHLAQVIRPALARGAVVLCDRFTD---A 100

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-KPDHQ 191
            + + G            ++ +   E  +        P L +   +  +   AR     +
Sbjct: 101 TYAYQGGG------RGLSVERIAILESFV---QGELRPDLTLVFDLPVEVGLARAAARGR 151

Query: 192 LAALQE---------KIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
           L   ++         + A   +      +   LD   P   + +A    +   L
Sbjct: 152 LDRFEQEGQAFFEAVRQAYLQRAGQQPQRYSLLDAAQPLAAVQRAIDALLPGIL 205


>UniRef50_A4A8F5 Thymidylate kinase n=1 Tax=Congregibacter litoralis KT71
           RepID=A4A8F5_9GAMM
          Length = 209

 Score =  107 bits (266), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 33/235 (14%), Positives = 73/235 (31%), Gaps = 43/235 (18%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            R+I + G +G+GK+T+  ++ + L                      ++ P  G P G  
Sbjct: 4   GRMIVVDGSNGAGKTTVIEAIRDHLQ-------------HVNRETVFTREPG-GTPIGEK 49

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFR-KMLCKSQQGFLLITDRYPQVEVP 132
           +R                     + L +  RA   R K++   + G ++++DR+    V 
Sbjct: 50  IREILLSPEAGEMADV-----TELMLFAAARAQHVREKIMPAVEAGKVVVSDRFDSATVS 104

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR--KPDH 190
              +              ++++               P + I L +D +    R      
Sbjct: 105 FQHY---------ARGLPLELITTLNEIAVD---GLKPDMTIILDLDPEAGLVRVGSRGD 152

Query: 191 QLAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAAL 236
            L  L+++         +G            + +D     D ++   L  +   +
Sbjct: 153 DLDRLEKEKLDFLHKARDGYLGQAKASPDNFVVIDASQSLDNVISEVLSVVDQVI 207


>UniRef50_C5AQT8 Thymidylate kinase n=14 Tax=Proteobacteria RepID=C5AQT8_METEA
          Length = 249

 Score =  107 bits (266), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 37/244 (15%), Positives = 68/244 (27%), Gaps = 48/244 (19%)

Query: 9   INSTPVR--VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVI 66
           ++S   R   I   G +G+GKST  A L   L      E +             ++ P  
Sbjct: 1   MSSDAPRGVFITFEGGEGAGKSTQIARLAETLRRVSGREVVT------------TREPG- 47

Query: 67  GAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRY 126
           G      LR+       +    P    A  +   +    +    +     +G +++ DR+
Sbjct: 48  GTERAEALRAALL----RGVAKPYGPFAEALMFAAARIDHIGNLIRPALDRGAIVLCDRF 103

Query: 127 PQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR 186
                    + G        G     ++   E    + +    P L + L +  +   AR
Sbjct: 104 SDST---RAYQGA------AGGLDPALIDSLERVTLEDL---RPDLTLILDLPPEAGLAR 151

Query: 187 KPDHQL---------------AALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRA 231
                                  L+       +      +   +D     D +  A   A
Sbjct: 152 ARRRGAGEPADRFEAEGMRFHERLRTAFRSIAEA--EPERCRVIDADLGPDAVETAIANA 209

Query: 232 IHAA 235
           I A 
Sbjct: 210 IAAR 213


>UniRef50_A1RYZ6 Thymidylate kinase n=1 Tax=Thermofilum pendens Hrk 5
           RepID=A1RYZ6_THEPD
          Length = 254

 Score =  107 bits (266), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 40/234 (17%), Positives = 76/234 (32%), Gaps = 51/234 (21%)

Query: 12  TPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFG 71
                +A+ G DGSGK+T  A L  +L+A                   I + P + A   
Sbjct: 52  DGGLYVALEGIDGSGKTTQAAMLYEKLSAEGFQVV-------------IVREPWVPA-IK 97

Query: 72  RYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVE 130
            +L      V  +            +YL +  R    R+ +L   + G ++++DR     
Sbjct: 98  EFLYKHDLDVEAE------------VYLFAADRIILQREVVLPSLRAGKIVVSDRSVFAS 145

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---- 186
           +      G         N  ++                 P +++ L +  + A  R    
Sbjct: 146 LAYQSSRGADQDFILAVNKSVRF----------------PDVVVLLDLPVEEAMKRLSSR 189

Query: 187 --KPDHQLAALQEKIA--VTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
             +   +     EK+             K + +D   P +E+ +  LR I + +
Sbjct: 190 VAQTRFEDPGYMEKVRAKYLQLAEEYPEKFIVVDASKPPEEVNREILREIVSIV 243


>UniRef50_A0LF96 Thymidylate kinase n=1 Tax=Syntrophobacter fumaroxidans MPOB
           RepID=A0LF96_SYNFM
          Length = 222

 Score =  107 bits (266), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 39/241 (16%), Positives = 74/241 (30%), Gaps = 45/241 (18%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           +     + +   G DG GKSTL   L + L                R+    ++ P  G 
Sbjct: 11  MKPISPKFVTFEGIDGCGKSTLIDELASWLDR-------------TRVPYVKTREPG-GT 56

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKM-LCKSQQGFLLITDRYP 127
             G  +R        +     G      + L +  RA    ++ L   + G  ++ DRY 
Sbjct: 57  SLGEKIRGLLLDPAHR-----GMNRQTEVLLYTASRAQLVAEIILPALKSGAWVLADRYI 111

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQW-MASYLPVLLIRLGIDEQTAFAR 186
              +    +               ++      +L  W   + +P   + L     TA AR
Sbjct: 112 DATLAYQGYG-------------RELDPDPLRRLQHWATQALVPDKTVLLDCGIDTAAAR 158

Query: 187 K--PDHQLAALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAA 235
               +H+   ++ +     +    G          + + LD   P  E++     A    
Sbjct: 159 MSARNHRPDRIEMEERAFHERVKAGYLDLASLDPGRFIVLDAEKPLPEVIADFRAAFREI 218

Query: 236 L 236
           +
Sbjct: 219 V 219


>UniRef50_C9RH19 Thymidylate kinase n=1 Tax=Methanocaldococcus vulcanius M7
           RepID=C9RH19_METVM
          Length = 187

 Score =  107 bits (266), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 34/222 (15%), Positives = 63/222 (28%), Gaps = 47/222 (21%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G DGSGK+T++  L   + A           S+  +GE I ++            
Sbjct: 2   FIVFEGIDGSGKTTISKKLAKSINAFWT-----YEPSNSVVGELIRKILSGNVKVDDK-- 54

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                               +  L S  R    +K+  + +    ++ DRY    +    
Sbjct: 55  -------------------TLALLFSADRIEHNKKIKEELR-YRDVVCDRYLYSSIAYQS 94

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---KPDHQL 192
             G               +R           +  P L+  L  D +TA  R   K   + 
Sbjct: 95  VAGV----------DEDFIRSINR------YALKPDLVFLLICDIETALKRINTKDIFEK 138

Query: 193 AALQEKIAVTPQLTFNGAKILELDGR-HPADEILQASLRAIH 233
               EK+             + +D      +++     + + 
Sbjct: 139 KEFLEKVQEKYLDLAKKEGFVIIDTTDRTVEDVYSEVFKTVK 180


>UniRef50_B9MNV9 Thymidylate kinase n=1 Tax=Anaerocellum thermophilum DSM 6725
           RepID=B9MNV9_ANATD
          Length = 208

 Score =  106 bits (265), Expect = 5e-22,   Method: Composition-based stats.
 Identities = 33/233 (14%), Positives = 68/233 (29%), Gaps = 42/233 (18%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            ++I   G DGSGK+T    +   L  +              +G  I +L +        
Sbjct: 4   GKLIVFEGNDGSGKTTQLVKVEKYLKEKGYKVLTTREPGGTEVGYRIRKLLLDPQY---- 59

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKML-CKSQQGFLLITDRYPQVEVP 132
                                    LL+  R    + +L     +G++++ DRY    V 
Sbjct: 60  ----------------KMDGLTEALLLAADRNEHVKNVLIPALDEGYIVLCDRYILSSV- 102

Query: 133 GFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD--- 189
              + G            +  + +             P L I L ++ + A  R      
Sbjct: 103 --VYQGIVRGVGVENILRLNSIFE---------DRIKPDLYIVLTLEPEIALQRIKMAGK 151

Query: 190 ------HQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                   L   +   +   +++    + + ++ +    E+ +  L  I   L
Sbjct: 152 NDRLDLEDLEFHRRVYSGFKEVSKWFERCVNIEAQGSEKEVFEKVLLEIEKLL 204


>UniRef50_Q2STA4 Thymidylate kinase n=6 Tax=Bacteria RepID=KTHY_MYCCT
          Length = 213

 Score =  106 bits (265), Expect = 5e-22,   Method: Composition-based stats.
 Identities = 33/233 (14%), Positives = 65/233 (27%), Gaps = 42/233 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G DGSGK+T    +  EL                     I++ P  G      +R
Sbjct: 2   FITFEGMDGSGKTTALLKVKEELERL-------------NYKVLITREPG-GEVIAEQIR 47

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                   K            +  ++    +  + +    ++  ++I+DR+         
Sbjct: 48  QIILDNKNKDMDAWTE----ALLFIASRNQHLQKVIKPALEKNIIVISDRFIDSTSA--- 100

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR--------K 187
           + G            ++ +          + + LP L +   +    A  R        K
Sbjct: 101 YQGSARNIGVDVVSEVQQIV---------LKNCLPDLTLFFDVSFSEAEKRMQIRGESSK 151

Query: 188 PDHQLAALQEKIAVTPQLTF----NGAKILELDGRHPADEILQASLRAIHAAL 236
                     K  V          N  +I  +D     D++   +++ I   L
Sbjct: 152 NRLDKEENNFKQKVYQGYLELVKNNPKRIKVIDANKDIDQVYNQAIKIILEKL 204


>UniRef50_Q3SBA4 Thymidilate kinase n=1 Tax=uncultured euryarchaeote Alv-FOS5
           RepID=Q3SBA4_9EURY
          Length = 212

 Score =  106 bits (265), Expect = 5e-22,   Method: Composition-based stats.
 Identities = 39/236 (16%), Positives = 67/236 (28%), Gaps = 51/236 (21%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G D SGK T    L   L  +                 ++   P    P G+ ++
Sbjct: 4   FIVFEGIDASGKETQAKLLAKALKKKGHKV-------------YMVDFPNYKNPIGKMIK 50

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                  E               L +  R Y+ + +        ++I DRY    +    
Sbjct: 51  KFLDKKVELDVETRA-------LLYAADRRYELKGITKALDDNKIVIADRYCYSNIA--- 100

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD----HQ 191
           + G            I  L   +  L        P L+  L I  + +  R+        
Sbjct: 101 YQGS-------LGANISWLASLDATLVF------PDLVFYLDIPAKESLRRRTRKDRYES 147

Query: 192 LAALQEKIAVTP-----------QLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                E++  T            +   + A+ + +DG  P D I +  L  +   L
Sbjct: 148 KREFLERVRETYTNMATGNMRPFEKYKDYAEWITVDGTLPIDIIHKEILMQVEMRL 203


>UniRef50_Q98MV4 Thymidylate kinase n=3 Tax=Alphaproteobacteria RepID=KTHY_RHILO
          Length = 224

 Score =  106 bits (265), Expect = 5e-22,   Method: Composition-based stats.
 Identities = 29/235 (12%), Positives = 66/235 (28%), Gaps = 44/235 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G +G+GKST    L  ++ A+     +          E +  + + G        
Sbjct: 6   FITFEGGEGAGKSTQIERLARKMHAKKYDVLLTREPGGSPGAEAVRHVLLSG-------- 57

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                     +  P       +   +    +  + +    ++G +++ DR+         
Sbjct: 58  ----------AAEPFGPKMEALLFAAARSDHVEQVIRPAVERGSIVLCDRFLDSS----- 102

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP-----DH 190
               ++ +   G      +   E      M   +P + +   ID      R       D 
Sbjct: 103 ----RVYQGVTGGIDPAFMATLEQIAINGM---MPDMTLIFDIDPAEGLRRATLRRGSDA 155

Query: 191 QLAALQEKIAVTPQ---------LTFNGAKILELDGRHPADEILQASLRAIHAAL 236
                +++     Q               + + +D     + +      A+ AAL
Sbjct: 156 GADRFEKETLAIHQARRAAFLAIAAAEPERCIVVDASADPNTVEDVVTAAVFAAL 210


>UniRef50_B4DBR3 dTMP kinase n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4DBR3_9BACT
          Length = 245

 Score =  106 bits (264), Expect = 6e-22,   Method: Composition-based stats.
 Identities = 33/247 (13%), Positives = 64/247 (25%), Gaps = 58/247 (23%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           +   +++A+ G DGSGKST    +   L                                
Sbjct: 25  NYSGKLLAVEGLDGSGKSTQIYLVKRWLELEGYRVFFT-------------------EWN 65

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVE 130
              L  K+    +K         +L+       R    R++L   + G+L++ DRY    
Sbjct: 66  SSILVKKSTSKGKKRQLLTPTTFSLIHATDFADRYE--RQILPLLRAGYLVLCDRYIF-- 121

Query: 131 VPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD- 189
                     LA+          + Q       +  + LP + +   +  +T+  R  + 
Sbjct: 122 --------TALARDAVRGVDRDWVEQL------YSFAVLPDITLYFRVPLETSLNRILEG 167

Query: 190 --------------------HQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASL 229
                                     Q K+    +        + +D             
Sbjct: 168 RPALKYHEAGLDMGWSTDPYESFRIFQGKVYAEYESMREKFGFVPVDATEEIHVQQAKVR 227

Query: 230 RAIHAAL 236
             I   +
Sbjct: 228 NLIKEKI 234


>UniRef50_Q7UIM1 Thymidylate kinase n=1 Tax=Rhodopirellula baltica RepID=KTHY_RHOBA
          Length = 245

 Score =  106 bits (264), Expect = 6e-22,   Method: Composition-based stats.
 Identities = 32/233 (13%), Positives = 65/233 (27%), Gaps = 41/233 (17%)

Query: 8   IINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIG 67
           I +  P R+I + G DG GKS+    L   L +            S  +G  +  + +  
Sbjct: 42  IAHPYPGRLITLDGIDGVGKSSQIEILAERLRSEGRNVLCVRDPGSTDLGTKLRAMLL-- 99

Query: 68  APFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYP 127
                             S    +     +  ++         +      G  +I+DR+ 
Sbjct: 100 -----------------DSDLEMHRRTEAMLFMASRCEMIESTLRSALADGVTVISDRFL 142

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK 187
              V              GG    + L Q             P + + L +  + +  R 
Sbjct: 143 LANVVYQS---------VGGEVDAQTLWQLGRLA---CGGVQPDVTLLLDLPAEISMQRV 190

Query: 188 PDHQLAALQE---------KIAVTPQLTFNGAKILELDGRHPADEILQASLRA 231
              +   ++          + A   +L   G +   +D     +E+ +     
Sbjct: 191 GG-EADRMESRGVDYMAKVRQAFLDELPNAGGRTHVIDASGTIEEVAETIAAI 242


>UniRef50_B0MX01 Putative uncharacterized protein n=1 Tax=Alistipes putredinis DSM
           17216 RepID=B0MX01_9BACT
          Length = 225

 Score =  106 bits (264), Expect = 7e-22,   Method: Composition-based stats.
 Identities = 34/199 (17%), Positives = 60/199 (30%), Gaps = 24/199 (12%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I + G DG+GKST    +    A      H                 PV G    R+LR
Sbjct: 2   LIVLEGLDGAGKSTQVELVRRMFAQEGVESHFLHFPRFDA--------PVYGELIARFLR 53

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
            +   V +           LV  L +  RA    ++ C    G  ++ DRY    V    
Sbjct: 54  GELGAVDKVD-------PYLVALLFAGDRADAAAQLRCWLDAGHAVVLDRYVYSNV---G 103

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGID---EQTAFARKPDHQL 192
           F   +L          + +   E   Y       P + + L +     +   +   +   
Sbjct: 104 FQCAKLPAGDRQEELRRWILDLEFGYY---GIPRPDVSLFLDVPFAFTEKKLSEVREGDD 160

Query: 193 AALQEKIAVTPQLTFNGAK 211
               +      + + +  +
Sbjct: 161 REYLKGERDIHEASLDLQR 179


>UniRef50_D2RCC7 dTMP kinase n=1 Tax=Gardnerella vaginalis 409-05 RepID=D2RCC7_GARVA
          Length = 234

 Score =  105 bits (262), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 36/238 (15%), Positives = 68/238 (28%), Gaps = 46/238 (19%)

Query: 11  STPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPF 70
           +     I+  G DG GK+T   +L + L +      +       ++G+ + ++ + G   
Sbjct: 27  ANKGLFISFEGIDGVGKTTQVEALKDYLQSLGREVVVTREPGGTQLGKTLREILLHGTSV 86

Query: 71  GRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQV 129
                +                      L +  RA    + +     +G ++ITDRY   
Sbjct: 87  SARTEA---------------------LLFAADRAQHVAQVIRPALSRGAVVITDRYIDS 125

Query: 130 EVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD 189
            +      G +L          +              S  P     L +  + AF R   
Sbjct: 126 SLAYQA-GGRELTMDDVRTLS-EWATD----------SLWPNRTYLLDMQPEDAFKRLHR 173

Query: 190 HQLA--------ALQEKIAVTPQLTFNGAKILELDGRHP----ADEILQASLRAIHAA 235
            Q          A + + A       +  +   LD         + I+Q     I   
Sbjct: 174 EQDRMESAGIDFARRTREAFLDLAQESADRYRVLDATFSAKSLFELIVQDVHNLIKEI 231


>UniRef50_A0RXT4 Thymidylate kinase n=1 Tax=Cenarchaeum symbiosum RepID=A0RXT4_CENSY
          Length = 186

 Score =  105 bits (262), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 33/173 (19%), Positives = 54/173 (31%), Gaps = 37/173 (21%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I I GCD +GK T    L   L  +     ++          +      +G    + L 
Sbjct: 7   IIVIEGCDQAGKQTQAGLLAGALNRKGRKARVF---------AFPDYTTPVGKMMKKQLE 57

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
            +            G    +   L +  R  K  ++   S  G + I DRY Q       
Sbjct: 58  GR------------GFEPRVFHCLAAANRWEKAGEIRAASSGGSVAILDRYRQSN----- 100

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP 188
                +          + L   +  L          ++I L I ++ AF RKP
Sbjct: 101 -----MVYGVLNGLSRRWLAGLDAGL------PRADVVILLDIKQKEAFRRKP 142


>UniRef50_Q4JAC4 Probable thymidylate kinase n=11 Tax=Sulfolobus RepID=KTHY_SULAC
          Length = 194

 Score =  105 bits (262), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 36/230 (15%), Positives = 69/230 (30%), Gaps = 48/230 (20%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
           +I+  G DGSGK+T++  +  +L                                     
Sbjct: 3   IISFEGIDGSGKTTISKIIYEKL----------------------LIEIGSNKKIILTSE 40

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
             +  + +            +  L +  RAY    +    Q   ++I DRY    +    
Sbjct: 41  PFSQEIIKLIEEIGWKDPISLALLFTADRAYHLNLLFK--QNPEIIIMDRYIDSTIAYQS 98

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKP------- 188
                             +R              P L I L +  +TA AR         
Sbjct: 99  ----------SLGIDENWIRNLNKYF------PEPDLTILLDLKPETAIARIKNKVDKFN 142

Query: 189 -DHQLAALQEKIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAALS 237
            D +++ L +      +L     KI  ++     DEI++ +   +++ L+
Sbjct: 143 FDEKISTLSKVREKYLELAKRNNKIRIVNAEKSIDEIVEETWSIVYSFLN 192


>UniRef50_Q0CE15 Thymidylate kinase n=1 Tax=Aspergillus terreus NIH2624
           RepID=Q0CE15_ASPTN
          Length = 175

 Score =  105 bits (261), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 23/149 (15%), Positives = 47/149 (31%), Gaps = 20/149 (13%)

Query: 96  VIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLR 155
           +  L S  R    + +      G  +I DRY           G         +  +    
Sbjct: 24  IHLLFSANRWEVAQSIERDVDNGTTVIVDRYSYSGAVYSAAKG-------NPSLSLGWAW 76

Query: 156 QRELKLYQWMASYLPVLLIRLGIDEQTAFARK----PDHQLAALQEKIAVTPQLTFNGAK 211
           Q E+ L        P L + L I  + A  R       ++   +Q ++    +  F+   
Sbjct: 77  QPEVGL------PRPDLCLFLQITPEEAAKRGGFGAERYENETMQTRVRELFKTIFDLQP 130

Query: 212 ---ILELDGRHPADEILQASLRAIHAALS 237
              +  +D      ++ Q   +A+   ++
Sbjct: 131 RGDVTVIDAGRSFQDVAQDMRKAVEDRIA 159


>UniRef50_B2V7X0 Thymidylate kinase n=3 Tax=Sulfurihydrogenibium RepID=KTHY_SULSY
          Length = 204

 Score =  105 bits (261), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 27/229 (11%), Positives = 62/229 (27%), Gaps = 40/229 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G + SGK+T    L + L +                   I      G   G+ +R
Sbjct: 4   FITFEGIEASGKTTQINLLYDYLKSIGKNV--------------IKTREPGGTKIGQKIR 49

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKM-LCKSQQGFLLITDRYPQVEVPGF 134
                  ++            + L    R    + +       G+++++DRY        
Sbjct: 50  EILLSKWDEK-----FPYIAELLLYESDRNIHIQSIVKPSLDAGYIVLSDRYIDSTTAYQ 104

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR------KP 188
            +               +++               P L   + I  + +  R      + 
Sbjct: 105 HY---------ARGIDYEIVSYLNTLATD---GLKPNLTFLIDIPVEISLKRLSESKDRI 152

Query: 189 DHQLAALQEKIAV--TPQLTFNGAKILELDGRHPADEILQASLRAIHAA 235
           + +     +K+             + + +DG     EI +  + ++   
Sbjct: 153 ESEDIEFHKKLREGFLKIAENEKGRFVVIDGTMDIMEIHKIIVDSLKQR 201


>UniRef50_A5EXE3 Thymidylate kinase n=1 Tax=Dichelobacter nodosus VCS1703A
           RepID=KTHY_DICNV
          Length = 203

 Score =  105 bits (261), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 38/232 (16%), Positives = 72/232 (31%), Gaps = 40/232 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I + G +GSGKS+   ++ + L     T               I+     G   G  
Sbjct: 3   GKFICLDGTEGSGKSSQIQAICSFLQQHGKTV--------------ITTREPGGTQIGEA 48

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           +R      H +P          ++ +L+    +    +L     G  +I+DR+       
Sbjct: 49  IRELVLSPHYQPQALTE-----LLLILAARHEHLQTVILPHLAAGTWVISDRFNDATYAY 103

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRL----GIDEQTAFARKPD 189
             +         G    +K+++  E  +    AS+ P L   L     I  +    R  D
Sbjct: 104 QGY---------GRGIDLKIIKTLEQII---QASFQPDLACILCLPEHIAAERVHNRAHD 151

Query: 190 HQLAALQE-----KIAVTPQLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
           H    L+      ++A              +D     + + Q     +   L
Sbjct: 152 HDRIELENRAFFARVAQGYHARAQLPHARFIDASGDQNSVFQQIRHHLELLL 203


>UniRef50_A1WSY9 Thymidylate kinase n=13 Tax=Proteobacteria RepID=KTHY_HALHL
          Length = 215

 Score =  105 bits (261), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 32/232 (13%), Positives = 69/232 (29%), Gaps = 40/232 (17%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I + G +G+GK+T   ++   L        ++            ++ P  G PFG  LR
Sbjct: 7   FITVEGLEGAGKTTCLQAIEQMLLEAGIDRPLF------------TREPG-GTPFGEALR 53

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFR 135
                    P        A  + + +    +  + +      G  +I+DR+       + 
Sbjct: 54  GALLD----PQYRGLTAEAEALTVFAARAEHLAQVIRPTLDAGRWVISDRFTD---ATYA 106

Query: 136 FDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR---KPDHQL 192
           + G            ++               + P   + L +D     +R   + D + 
Sbjct: 107 YQGGGRGLGDERIAVLERWVH---------GGFTPDRTLLLDVDPTVGRSRVAHRGDGED 157

Query: 193 AALQEKIAVTP--------QLTFNGAKILELDGRHPADEILQASLRAIHAAL 236
              QE+             +   +  +   +D   P  E+ +     +   L
Sbjct: 158 RFEQERDPFFQAARAAYARRAAADPERFRCIDANRPEGEVAEQVRAGVADLL 209


>UniRef50_A0B8K1 Thymidylate kinase n=1 Tax=Methanosaeta thermophila PT
           RepID=A0B8K1_METTP
          Length = 202

 Score =  104 bits (260), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 36/237 (15%), Positives = 74/237 (31%), Gaps = 53/237 (22%)

Query: 9   INSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGA 68
           + +    +I + G DG+GK+T+   L                          ++ P  G 
Sbjct: 1   MRADRGILITLEGIDGAGKTTVARMLRKRF-----------------PDFVFTREPTDG- 42

Query: 69  PFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYP 127
           P G   R  +                  ++L     A   R  +L     G ++++DRY 
Sbjct: 43  PLGEMARRASGFEQ--------------LFLFMADHANHLRSCILPSINSGEVVVSDRYI 88

Query: 128 QVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARK 187
              V    + G  L         ++ + +          S +P L +   ID   A  R 
Sbjct: 89  DSRVA---YQGALL----RRTISMEWIYELHR-----PWSLMPDLTLLFRIDPSVALMRC 136

Query: 188 PDHQLAALQEKIAVTPQLTFNG--------AKILELDGRHPADEILQASLRAIHAAL 236
            +    ++ E  A+   ++ N          + + ++      E+ + +   I   +
Sbjct: 137 KNRGATSIFEMEALLRDVSGNFEILASREPERFVIINAEREISEVAERAASEIERFI 193


>UniRef50_C0QTF2 Thymidylate kinase n=1 Tax=Persephonella marina EX-H1
           RepID=C0QTF2_PERMH
          Length = 216

 Score =  104 bits (260), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 29/231 (12%), Positives = 66/231 (28%), Gaps = 42/231 (18%)

Query: 16  VIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRYLR 75
            I   G +G+GKST +  L   L        +        +G+ I ++ +          
Sbjct: 14  FITFEGIEGAGKSTQSKMLYEYLIKNGKNAVLTREPGGTDLGKKIREILL---------- 63

Query: 76  SKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRK-MLCKSQQGFLLITDRYPQVEVPGF 134
                      +         + L    R       +     +GF +I+DR+    +   
Sbjct: 64  ---------NPSKEIFPPVAELMLYEADRNIHVHNIIKPYLNRGFYVISDRFTDSTLAYQ 114

Query: 135 RFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPD-HQLA 193
            +              I+++ +      +      P +   + I  +    R     +  
Sbjct: 115 GY---------ARGIDIELVERLNDIASE---GIKPDITFIIDIPVEEGMKRIHRYREKD 162

Query: 194 ALQEKIAVTPQLTFNG---------AKILELDGRHPADEILQASLRAIHAA 235
            ++++     +    G          +++ LDGR   + I    L  +   
Sbjct: 163 RIEQEGVDFHKRLREGFLRIAQKERERVVLLDGRKDKEIIFNEILEILRKR 213


>UniRef50_A1AVP9 Thymidylate kinase n=2 Tax=sulfur-oxidizing symbionts
           RepID=KTHY_RUTMC
          Length = 205

 Score =  104 bits (260), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 34/233 (14%), Positives = 78/233 (33%), Gaps = 41/233 (17%)

Query: 14  VRVIAIVGCDGSGKSTLTASLVNELAARMPTEHIYLGQSSGRIGEWISQLPVIGAPFGRY 73
            + I I G +GSGKST    + + L              + +I   +++ P  G   G  
Sbjct: 4   GKFITIDGVEGSGKSTQIDFICDYL-------------VTKKINVILTREPG-GTELGEK 49

Query: 74  LRSKAAHVHEKPSTPPGNITALVIYLLSCWRAYKFRKMLCKSQQGFLLITDRYPQVEVPG 133
           +R+       +           ++ L +    +   K++   ++G  +++DR+       
Sbjct: 50  IRTLLLSTDIQSIHGDTE----LLLLFAARNEHIRTKIIPSLEKGDWVLSDRFTD---AS 102

Query: 134 FRFDGPQLAKTTGGNGWIKMLRQRELKLYQWMASYLPVLLIRLGIDEQTAFAR-KPDHQL 192
           + + G            I+ + Q E  + Q      P + + L +      +R +   + 
Sbjct: 103 YAYQGGG------RGLSIERITQLEKWVLQDFT---PDVTLLLDVSVALGMSRVESRGRK 153

Query: 193 AALQEKIAVTPQLTFNGA---------KILELDGRHPADEILQASLRAIHAAL 236
             ++ +     +   N           +I  +D     ++  Q   + I   L
Sbjct: 154 DRIELETNDFFKRVRNSYIERSKQFPKRIKLIDASKTLEQTAQQI-KIILQVL 205


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.310    0.118    0.318 

Lambda     K      H
   0.267   0.0362    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,147,097,349
Number of Sequences: 3077464
Number of extensions: 37835410
Number of successful extensions: 231003
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 465
Number of HSP's successfully gapped in prelim test: 364
Number of HSP's that attempted gapping in prelim test: 229108
Number of HSP's gapped (non-prelim): 925
length of query: 237
length of database: 1,040,396,356
effective HSP length: 125
effective length of query: 112
effective length of database: 655,713,356
effective search space: 73439895872
effective search space used: 73439895872
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.4 bits)
S2: 90 (39.5 bits)
