Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	S	S	N	L	I	K	Q	L	Q	E	R	G	L	V	A	Q	V	T	D	E	E	A	L	A	E	R	L	A	Q	G	P	I	A	L	Y	C	G	F	D	P	T	A	D	S	L	H	L	G	H	L	V	P	L	L	C	L	K	R
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		F	Q	Q	A	G	H	K	P	V	A	L	V	G	G	A	T	G	L	I	G	D	P	S	F	K	A	A	E	R	K	L	N	T	E	E	T	V	Q	E	W	V	D	K	I	R	K	Q	V	A	P	F	L	D	F	D	C	G	E	N	S
Secondary structure
SS confidence
Disorder																											?	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	I	A	A	N	N	Y	D	W	F	G	N	M	N	V	L	T	F	L	R	D	I	G	K	H	F	S	V	N	Q	M	I	N	K	E	A	V	K	Q	R	L	N	R	E	D	Q	G	I	S	F	T	E	F	S	Y	N	L	L	Q	G
Secondary structure
SS confidence
Disorder																																											?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Y	D	F	A	C	L	N	K	Q	Y	G	V	V	L	Q	I	G	G	S	D	Q	W	G	N	I	T	S	G	I	D	L	T	R	R	L	H	Q	N	Q	V	F	G	L	T	V	P	L	I	T	K	A	D	G	T	K	F	G	K	T	E
Secondary structure
SS confidence
Disorder																																																				?	?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	G	A	V	W	L	D	P	K	K	T	S	P	Y	K	F	Y	Q	F	W	I	N	T	A	D	A	D	V	Y	R	F	L	K	F	F	T	F	M	S	I	E	E	I	N	A	L	E	E	E	D	K	N	S	G	K	A	P	R	A	Q
Secondary structure
SS confidence
Disorder																																																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		Y	V	L	A	E	Q	V	T	R	L	V	H	G	E	E	G	L	Q	A	A	K	R	I	T	E	C	L	F	S	G	S	L	S	A	L	S	E	A	D	F	E	Q	L	A	Q	D	G	V	P	M	V	E	M	E	K	G	A	D	L	M
Secondary structure
SS confidence
Disorder																																?	?	?	?	?	?	?	?	?				?	?	?					?				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		Q	A	L	V	D	S	E	L	Q	P	S	R	G	Q	A	R	K	T	I	A	S	N	A	I	T	I	N	G	E	K	Q	S	D	P	E	Y	F	F	K	E	E	D	R	L	F	G	R	F	T	L	L	R	R	G	K	K	N	Y	C	L
Secondary structure
SS confidence
Disorder							?			?	?	?	?																?						?
Disorder confidence
		.	.	.	.
Sequence		I	C	W	K
Secondary structure
SS confidence
Disorder					?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2jan chain D Region: 6 - 423 Aligned: 402 Modelled: 404 Confidence: 100.0% Identity: 47% PDB header:ligase Chain: D: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: tyrosyl-trna synthetase from mycobacterium tuberculosis in2 unliganded state Phyre2 PDB 1h3e chain A Region: 3 - 423 Aligned: 405 Modelled: 416 Confidence: 100.0% Identity: 25% PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: tyrosyl-trna synthetase from thermus thermophilus complexed2 with wild-type trnatyr(gua) and with atp and tyrosinol Phyre2 PDB 2rkj chain M Region: 2 - 327 Aligned: 325 Modelled: 326 Confidence: 100.0% Identity: 36% PDB header:ligase/rna Chain: M: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: cocrystal structure of a tyrosyl-trna synthetase splicing2 factor with a group i intron rna Phyre2 PDB 2pid chain B Region: 6 - 327 Aligned: 308 Modelled: 322 Confidence: 100.0% Identity: 43% PDB header:ligase Chain: B: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of human mitochondrial tyrosyl-trna synthetase in2 complex with an adenylate analog Phyre2 PDB 1x8x chain A Region: 1 - 322 Aligned: 322 Modelled: 322 Confidence: 100.0% Identity: 100% PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: tyrosyl t-rna synthetase from e.coli complexed with tyrosine Phyre2 PDB 1jil chain A Region: 3 - 328 Aligned: 322 Modelled: 326 Confidence: 100.0% Identity: 53% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 1jii chain A Region: 3 - 324 Aligned: 318 Modelled: 319 Confidence: 100.0% Identity: 53% PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of s. aureus tyrrs in complex with sb-219383 Phyre2 PDB 2ts1 chain A Region: 4 - 324 Aligned: 317 Modelled: 321 Confidence: 100.0% Identity: 62% PDB header:ligase (synthetase) Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: structure of tyrosyl-t/rna synthetase refined at 2.3 angstroms2 resolution. interaction of the enzyme with the tyrosyl adenylate3 intermediate Phyre2 PDB 2ts1 chain A Region: 4 - 324 Aligned: 317 Modelled: 321 Confidence: 100.0% Identity: 62% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 1h3f chain A domain 1 Region: 3 - 332 Aligned: 293 Modelled: 304 Confidence: 100.0% Identity: 27% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 2cyb chain A Region: 9 - 311 Aligned: 280 Modelled: 291 Confidence: 100.0% Identity: 20% PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with2 l-tyrosine from archaeoglobus fulgidus Phyre2 PDB 2qui chain B Region: 10 - 336 Aligned: 307 Modelled: 320 Confidence: 100.0% Identity: 16% PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structures of human tryptophanyl-trna synthetase in2 complex with tryptophanamide and atp Phyre2 PDB 2cya chain A Region: 1 - 328 Aligned: 302 Modelled: 318 Confidence: 100.0% Identity: 18% PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase from aeropyrum pernix Phyre2 PDB 3jxe chain B Region: 10 - 330 Aligned: 293 Modelled: 318 Confidence: 100.0% Identity: 15% PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of pyrococcus horikoshii tryptophanyl-trna2 synthetase in complex with trpamp Phyre2 PDB 2cyc chain B Region: 1 - 312 Aligned: 295 Modelled: 308 Confidence: 100.0% Identity: 18% PDB header:ligase Chain: B: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with l-tyrosine2 from pyrococcus horikoshii Phyre2 PDB 3foc chain B Region: 10 - 320 Aligned: 292 Modelled: 311 Confidence: 100.0% Identity: 19% PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase from giardia lamblia Phyre2 PDB 2el7 chain A Region: 35 - 372 Aligned: 303 Modelled: 335 Confidence: 100.0% Identity: 13% PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from thermus2 thermophilus Phyre2 PDB 3hzr chain D Region: 10 - 320 Aligned: 288 Modelled: 311 Confidence: 100.0% Identity: 10% PDB header:ligase Chain: D: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase homolog from entamoeba histolytica Phyre2 PDB 1q11 chain A Region: 9 - 312 Aligned: 287 Modelled: 304 Confidence: 100.0% Identity: 17% PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of an active fragment of human tyrosyl-trna2 synthetase with tyrosinol Phyre2 PDB 1r6t chain A domain 2 Region: 10 - 320 Aligned: 291 Modelled: 303 Confidence: 100.0% Identity: 15% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 1 c2janD_ 2 c1h3eA_ 3 c2rkjM_ 4 c2pidB_ 5 c1x8xA_ 6 d1jila_ 7 c1jiiA_ 8 c2ts1A_ 9 d2ts1a_ 10 d1h3fa1 11 c2cybA_ 12 c2quiB_ 13 c2cyaA_ 14 c3jxeB_ 15 c2cycB_ 16 c3focB_ 17 c2el7A_ 18 c3hzrD_ 19 c1q11A_ 20 d1r6ta2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2janD_ 100.0 47 PDB header:ligase Chain: D: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: tyrosyl-trna synthetase from mycobacterium tuberculosis in2 unliganded state 2 c1h3eA_ 100.0 25 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: tyrosyl-trna synthetase from thermus thermophilus complexed2 with wild-type trnatyr(gua) and with atp and tyrosinol 3 c2rkjM_ 100.0 36 PDB header:ligase/rna Chain: M: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: cocrystal structure of a tyrosyl-trna synthetase splicing2 factor with a group i intron rna 4 c2pidB_ 100.0 43 PDB header:ligase Chain: B: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of human mitochondrial tyrosyl-trna synthetase in2 complex with an adenylate analog 5 c1x8xA_ 100.0 100 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: tyrosyl t-rna synthetase from e.coli complexed with tyrosine 6 d1jila_ 100.0 53 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 7 c1jiiA_ 100.0 53 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of s. aureus tyrrs in complex with sb-219383 8 c2ts1A_ 100.0 62 PDB header:ligase (synthetase) Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: structure of tyrosyl-t/rna synthetase refined at 2.3 angstroms2 resolution. interaction of the enzyme with the tyrosyl adenylate3 intermediate 9 d2ts1a_ 100.0 62 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 10 d1h3fa1 100.0 27 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 11 c2cybA_ 100.0 20 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with2 l-tyrosine from archaeoglobus fulgidus 12 c2quiB_ 100.0 16 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structures of human tryptophanyl-trna synthetase in2 complex with tryptophanamide and atp 13 c2cyaA_ 100.0 18 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase from aeropyrum pernix 14 c3jxeB_ 100.0 15 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of pyrococcus horikoshii tryptophanyl-trna2 synthetase in complex with trpamp 15 c2cycB_ 100.0 18 PDB header:ligase Chain: B: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with l-tyrosine2 from pyrococcus horikoshii 16 c3focB_ 100.0 19 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase from giardia lamblia 17 c2el7A_ 100.0 13 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from thermus2 thermophilus 18 c3hzrD_ 100.0 10 PDB header:ligase Chain: D: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase homolog from entamoeba histolytica 19 c1q11A_ 100.0 17 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of an active fragment of human tyrosyl-trna2 synthetase with tyrosinol 20 d1r6ta2 100.0 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 21 d1j1ua_ not modelled 100.0 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 22 c3p0jD_ not modelled 100.0 16 PDB header:ligase Chain: D: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: leishmania major tyrosyl-trna synthetase in complex with tyrosinol,2 triclinic crystal form 1 23 c1r6uB_ not modelled 100.0 16 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of an active fragment of human tryptophanyl-trna2 synthetase with cytokine activity 24 c3i05B_ not modelled 100.0 19 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase from trypanosoma brucei 25 c3a05A_ not modelled 100.0 17 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from2 hyperthermophilic archaeon, aeropyrum pernix k1 complex3 with tryptophan 26 c3hv0A_ not modelled 100.0 16 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase from cryptosporidium parvum 27 d1n3la_ not modelled 100.0 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 28 c2dlcX_ not modelled 100.0 16 PDB header:ligase/trna Chain: X: PDB Molecule:tyrosyl-trna synthetase, cytoplasmic; PDBTitle: crystal structure of the ternary complex of yeast tyrosyl-trna2 synthetase 29 c1yi8C_ not modelled 100.0 20 PDB header:ligase Chain: C: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl trrna synthetase ii from deinococcus2 radiodurans in complex with l-trp 30 c2ip1A_ not modelled 100.0 15 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure analysis of s. cerevisiae tryptophanyl trna2 synthetase 31 d1i6la_ not modelled 100.0 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 32 c3n9iA_ not modelled 100.0 15 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from yersinia pestis2 co92 33 c2j5bA_ not modelled 100.0 15 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: structure of the tyrosyl trna synthetase from acanthamoeba2 polyphaga mimivirus complexed with tyrosynol 34 c3m5wB_ not modelled 100.0 16 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from2 campylobacter jejuni 35 c3sz3A_ not modelled 100.0 14 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from vibrio cholerae2 with an endogenous tryptophan 36 c2g36A_ not modelled 100.0 20 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase (ec 6.1.1.2)2 (tryptophan-trna ligase)(trprs) (tm0492) from thermotoga maritima at3 2.50 a resolution 37 c3prhB_ not modelled 100.0 15 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase val144pro mutant from b. subtilis 38 c2yy5C_ not modelled 100.0 16 PDB header:ligase Chain: C: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from mycoplasma2 pneumoniae 39 d1jh3a_ not modelled 99.9 41 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Tyrosyl-tRNA synthetase (TyrRS), C-terminal domain 40 d1h3fa2 not modelled 99.7 26 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Tyrosyl-tRNA synthetase (TyrRS), C-terminal domain 41 c2ktlA_ not modelled 98.9 18 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: structure of c-terminal domain from mttyrrs of a. nidulans 42 c2x1lC_ not modelled 98.8 14 PDB header:ligase Chain: C: PDB Molecule:methionyl-trna synthetase; PDBTitle: crystal structure of mycobacterium smegmatis methionyl-trna2 synthetase in complex with methionine and adenosine 43 d1li5a2 not modelled 98.7 13 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 44 c3tqoA_ not modelled 98.7 12 PDB header:ligase Chain: A: PDB Molecule:cysteinyl-trna synthetase; PDBTitle: structure of the cysteinyl-trna synthetase (cyss) from coxiella2 burnetii. 45 d1pfva2 not modelled 98.6 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 46 c2ct8A_ not modelled 98.6 15 PDB header:ligase/rna Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: crystal structure of aquifex aeolicus methionyl-trna2 synthetase complexed with trna(met) and methionyl-adenylate3 anologue 47 c3c8zB_ not modelled 98.5 17 PDB header:ligase Chain: B: PDB Molecule:cysteinyl-trna synthetase; PDBTitle: the 1.6 a crystal structure of mshc: the rate limiting2 enzyme in the mycothiol biosynthetic pathway 48 c1u0bB_ not modelled 98.5 16 PDB header:ligase/rna Chain: B: PDB Molecule:cysteinyl trna; PDBTitle: crystal structure of cysteinyl-trna synthetase binary2 complex with trnacys 49 c2cfoA_ not modelled 98.4 16 PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: non-discriminating glutamyl-trna synthetase from2 thermosynechococcus elongatus in complex with glu 50 d1rqga2 not modelled 98.4 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 51 c3fnrA_ not modelled 98.3 15 PDB header:transferase Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of putative arginyl t-rna synthetase from2 campylobacter jejuni; 52 d1gtra2 not modelled 98.1 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 53 d1ilea3 not modelled 98.1 25 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 54 c3sp1B_ not modelled 98.1 17 PDB header:ligase Chain: B: PDB Molecule:cysteinyl-trna synthetase; PDBTitle: crystal structure of cysteinyl-trna synthetase (cyss) from borrelia2 burgdorferi 55 d1ivsa4 not modelled 98.0 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 56 c1qu2A_ not modelled 98.0 24 PDB header:ligase/rna Chain: A: PDB Molecule:isoleucyl-trna synthetase; PDBTitle: insights into editing from an ile-trna synthetase structure2 with trna(ile) and mupirocin 57 d1ffya3 not modelled 98.0 24 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 58 c1ileA_ not modelled 98.0 20 PDB header:aminoacyl-trna synthetase Chain: A: PDB Molecule:isoleucyl-trna synthetase; PDBTitle: isoleucyl-trna synthetase 59 c1gaxB_ not modelled 97.9 17 PDB header:ligase/rna Chain: B: PDB Molecule:valyl-trna synthetase; PDBTitle: crystal structure of thermus thermophilus valyl-trna2 synthetase complexed with trna(val) and valyl-adenylate3 analogue 60 c2cqjA_ not modelled 97.8 15 PDB header:rna binding protein Chain: A: PDB Molecule:u3 small nucleolar ribonucleoprotein protein PDBTitle: solution structure of the s4 domain of u3 small nucleolar2 ribonucleoprotein protein imp3 homolog 61 d2d5ba2 not modelled 97.8 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 62 d1c06a_ not modelled 97.8 23 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Ribosomal protein S4 63 c3kflA_ not modelled 97.7 14 PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: leishmania major methionyl-trna synthetase in complex with2 methionyladenylate and pyrophosphate 64 c1wkbA_ not modelled 97.7 20 PDB header:ligase Chain: A: PDB Molecule:leucyl-trna synthetase; PDBTitle: crystal structure of leucyl-trna synthetase from the2 archaeon pyrococcus horikoshii reveals a novel editing3 domain orientation 65 c1pfuA_ not modelled 97.7 13 PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: methionyl-trna synthetase from escherichia coli complexed2 with methionine phosphinate 66 d2uubd1 not modelled 97.6 28 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Ribosomal protein S4 67 c1woyA_ not modelled 97.6 15 PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: crystal structure of methionyl trna synthetase y225f mutant2 from thermus thermophilus 68 c1g59A_ not modelled 97.6 17 PDB header:ligase/rna Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: glutamyl-trna synthetase complexed with trna(glu). 69 d1p9ka_ not modelled 97.5 16 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:YbcJ-like 70 c3afhA_ not modelled 97.5 12 PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase 2; PDBTitle: crystal structure of thermotoga maritima nondiscriminating glutamyl-2 trna synthetase in complex with a glutamyl-amp analog 71 d1dm9a_ not modelled 97.5 24 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Heat shock protein 15 kD 72 c1dm9A_ not modelled 97.5 24 PDB header:structural genomics Chain: A: PDB Molecule:hypothetical 15.5 kd protein in mrca-pcka PDBTitle: heat shock protein 15 kd 73 d2gy9d1 not modelled 97.4 21 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Ribosomal protein S4 74 c1wz2B_ not modelled 97.4 16 PDB header:ligase/rna Chain: B: PDB Molecule:leucyl-trna synthetase; PDBTitle: the crystal structure of leucyl-trna synthetase and trna(leucine)2 complex 75 c3bbnD_ not modelled 97.3 26 PDB header:ribosome Chain: D: PDB Molecule:ribosomal protein s4; PDBTitle: homology model for the spinach chloroplast 30s subunit2 fitted to 9.4a cryo-em map of the 70s chlororibosome. 76 c1s1hD_ not modelled 97.3 19 PDB header:ribosome Chain: D: PDB Molecule:40s ribosomal protein s9-a; PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from2 yeast obtained by docking atomic models for rna and protein3 components into a 11.7 a cryo-em map. this file, 1s1h,4 contains 40s subunit. the 60s ribosomal subunit is in file5 1s1i. 77 c2xzmD_ not modelled 97.2 13 PDB header:ribosome Chain: D: PDB Molecule:ribosomal protein s4 containing protein; PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 1 78 c2o5rA_ not modelled 97.1 11 PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase 1; PDBTitle: crystal structure of glutamyl-trna synthetase 1 (ec 6.1.1.17)2 (glutamate-trna ligase 1) (glurs 1) (tm1351) from thermotoga maritima3 at 2.5 a resolution 79 c2ja2A_ not modelled 97.0 14 PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: mycobacterium tuberculosis glutamyl-trna synthetase 80 c1irxA_ not modelled 96.8 16 PDB header:ligase Chain: A: PDB Molecule:lysyl-trna synthetase; PDBTitle: crystal structure of class i lysyl-trna synthetase 81 d1vioa2 not modelled 96.8 27 Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Pseudouridine synthase RsuA N-terminal domain 82 c1kskA_ not modelled 96.4 19 PDB header:lyase Chain: A: PDB Molecule:ribosomal small subunit pseudouridine synthase a; PDBTitle: structure of rsua 83 d1f7ua2 not modelled 96.4 13 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 84 c1obhA_ not modelled 96.4 22 PDB header:synthetase Chain: A: PDB Molecule:leucyl-trna synthetase; PDBTitle: leucyl-trna synthetase from thermus thermophilus complexed2 with a pre-transfer editing substrate analogue in both3 synthetic active site and editing site 85 c3al0C_ not modelled 96.3 15 PDB header:ligase/rna Chain: C: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit c, glutamyl- PDBTitle: crystal structure of the glutamine transamidosome from thermotoga2 maritima in the glutamylation state. 86 c1rqgA_ not modelled 96.3 13 PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: methionyl-trna synthetase from pyrococcus abyssi 87 c3dh3C_ not modelled 96.2 19 PDB header:isomerase/rna Chain: C: PDB Molecule:ribosomal large subunit pseudouridine synthase f; PDBTitle: crystal structure of rluf in complex with a 22 nucleotide2 rna substrate 88 c1vioA_ not modelled 96.2 24 PDB header:lyase Chain: A: PDB Molecule:ribosomal small subunit pseudouridine synthase a; PDBTitle: crystal structure of pseudouridylate synthase 89 c3hp7A_ not modelled 96.1 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hemolysin, putative; PDBTitle: putative hemolysin from streptococcus thermophilus. 90 d1irxa2 not modelled 95.9 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 91 c2hz7A_ not modelled 95.6 18 PDB header:ligase Chain: A: PDB Molecule:glutaminyl-trna synthetase; PDBTitle: crystal structure of the glutaminyl-trna synthetase from2 deinococcus radiodurans 92 d1h3na3 not modelled 95.5 23 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 93 c3kbgA_ not modelled 95.3 13 PDB header:ribosomal protein Chain: A: PDB Molecule:30s ribosomal protein s4e; PDBTitle: crystal structure of the 30s ribosomal protein s4e from2 thermoplasma acidophilum. northeast structural genomics3 consortium target tar28. 94 c3iz6D_ not modelled 93.5 15 PDB header:ribosome Chain: D: PDB Molecule:40s ribosomal protein s4 (s4e); PDBTitle: localization of the small subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome 95 c2zufA_ not modelled 92.9 16 PDB header:ligase/rna Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of pyrococcus horikoshii arginyl-trna2 synthetase complexed with trna(arg) 96 c2xzmW_ not modelled 92.9 14 PDB header:ribosome Chain: W: PDB Molecule:40s ribosomal protein s4; PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 1 97 c2k6pA_ not modelled 92.6 21 PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein hp_1423; PDBTitle: solution structure of hypothetical protein, hp1423 98 c3izbD_ not modelled 92.3 15 PDB header:ribosome Chain: D: PDB Molecule:40s ribosomal protein rps4 (s4e); PDBTitle: localization of the small subunit ribosomal proteins into a 6.1 a2 cryo-em map of saccharomyces cerevisiae translating 80s ribosome 99 d1j09a2 not modelled 91.8 22 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 100 c3iz6C_ not modelled 91.5 18 PDB header:ribosome Chain: C: PDB Molecule:40s ribosomal protein s9 (s4p); PDBTitle: localization of the small subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome 101 c1iq0A_ not modelled 90.1 31 PDB header:ligase Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: thermus thermophilus arginyl-trna synthetase 102 d1iq0a2 not modelled 89.6 28 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 103 c1exdA_ not modelled 88.5 14 PDB header:ligase/rna Chain: A: PDB Molecule:glutaminyl-trna synthetase; PDBTitle: crystal structure of a tight-binding glutamine trna bound2 to glutamine aminoacyl trna synthetase 104 d1nzja_ not modelled 87.8 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 105 c3aiiA_ not modelled 86.6 12 PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: archaeal non-discriminating glutamyl-trna synthetase from2 methanothermobacter thermautotrophicus 106 c1f7uA_ not modelled 80.8 16 PDB header:ligase/rna Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of the arginyl-trna synthetase complexed with the2 trna(arg) and l-arg 107 c2jqlA_ not modelled 72.3 27 PDB header:cell cycle Chain: A: PDB Molecule:dna damage response protein kinase dun1; PDBTitle: nmr structure of the yeast dun1 fha domain in complex with2 a doubly phosphorylated (pt) peptide derived from rad533 scd1 108 c3fm8A_ not modelled 67.9 11 PDB header:transport protein/hydrolase activator Chain: A: PDB Molecule:kinesin-like protein kif13b; PDBTitle: crystal structure of full length centaurin alpha-1 bound with the fha2 domain of kif13b (capri target) 109 d2g1la1 not modelled 63.4 14 Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain 110 c3uk2B_ not modelled 60.4 22 PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: the structure of pantothenate synthetase from burkholderia2 thailandensis 111 d1wd5a_ not modelled 57.8 13 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 112 d1v8fa_ not modelled 53.7 30 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) 113 c1yunB_ not modelled 53.1 23 PDB header:transferase Chain: B: PDB Molecule:probable nicotinate-nucleotide PDBTitle: crystal structure of nicotinic acid mononucleotide2 adenylyltransferase from pseudomonas aeruginosa 114 c2eh0A_ not modelled 52.9 17 PDB header:transport protein Chain: A: PDB Molecule:kinesin-like protein kif1b; PDBTitle: solution structure of the fha domain from human kinesin-2 like protein kif1b 115 d1jhda2 not modelled 51.4 12 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:ATP sulfurylase catalytic domain 116 c3nd5D_ not modelled 51.1 31 PDB header:transferase Chain: D: PDB Molecule:phosphopantetheine adenylyltransferase; PDBTitle: crystal structure of phosphopantetheine adenylyltransferase (ppat)2 from enterococcus faecalis 117 c3n8hA_ not modelled 47.0 20 PDB header:ligase Chain: A: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantoate-beta-alanine ligase from francisella2 tularensis 118 c3guzB_ not modelled 43.4 14 PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: structural and substrate-binding studies of pantothenate2 synthenate (ps)provide insights into homotropic inhibition3 by pantoate in ps's 119 c3ag5A_ not modelled 42.5 20 PDB header:ligase Chain: A: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantothenate synthetase from staphylococcus2 aureus 120 c2kklA_ not modelled 40.2 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein mb1858; PDBTitle: solution nmr structure of fha domain of mb1858 from2 mycobacterium bovis. northeast structural genomics3 consortium target mbr243c (24-155).

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0