BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (277 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P45563 Xanthosine phosphorylase n=57 Tax=cellular organ...   570   e-161
UniRef50_B5R3U9 Xanthosine phosphorylase n=53 Tax=Enterobacteria...   512   e-144
UniRef50_Q472Z5 Purine nucleotide phosphorylase:Inosine guanosin...   290   4e-77
UniRef50_B6J4B4 Xanthosine phosphorylase n=8 Tax=Gammaproteobact...   271   2e-71
UniRef50_A5IBS6 Xanthosine phosphorylase n=5 Tax=Legionella RepI...   257   3e-67
UniRef50_A7GSB0 Purine nucleoside phosphorylase I, inosine and g...   249   7e-65
UniRef50_A0NS72 Purine nucleoside phosphorylase n=7 Tax=Alphapro...   246   6e-64
UniRef50_Q65HU0 PunA n=9 Tax=Firmicutes RepID=Q65HU0_BACLD            246   7e-64
UniRef50_P46354 Purine nucleoside phosphorylase 1 n=69 Tax=Bacte...   245   1e-63
UniRef50_P77834 Purine nucleoside phosphorylase 1 n=41 Tax=Bacil...   244   3e-63
UniRef50_Q2B6A0 Purine nucleoside phosphorylase n=12 Tax=Bacilli...   240   5e-62
UniRef50_B1YM96 Purine nucleoside phosphorylase I, inosine and g...   239   6e-62
UniRef50_Q1IM44 Purine nucleoside phosphorylase I, inosine and g...   234   2e-60
UniRef50_B9MKK7 Inosine guanosine and xanthosine phosphorylase f...   222   9e-57
UniRef50_A3DEQ4 Purine nucleoside phosphorylase I, inosine and g...   220   3e-56
UniRef50_B8HVY6 Inosine guanosine and xanthosine phosphorylase f...   219   1e-55
UniRef50_C1F7J2 Purine nucleoside phosphorylase I, inosine and g...   215   1e-54
UniRef50_A6BDL0 Putative uncharacterized protein n=1 Tax=Dorea l...   215   1e-54
UniRef50_A6NWZ5 Putative uncharacterized protein n=1 Tax=Bactero...   214   2e-54
UniRef50_A5USV0 Inosine guanosine and xanthosine phosphorylase f...   214   3e-54
UniRef50_A6GZM2 Purine-nucleoside phosphorylase n=3 Tax=Bacteroi...   214   4e-54
UniRef50_Q11C51 Inosine guanosine and xanthosine phosphorylase f...   212   1e-53
UniRef50_Q0TU47 Purine nucleoside phosphorylase n=7 Tax=Clostrid...   210   4e-53
UniRef50_C7M8V2 Inosine guanosine and xanthosine phosphorylase f...   209   6e-53
UniRef50_C1TMH4 Purine nucleoside phosphorylase I, inosine and g...   209   8e-53
UniRef50_A9KIE8 Inosine guanosine and xanthosine phosphorylase f...   207   4e-52
UniRef50_D0NTD2 Purine nucleoside phosphorylase 1 n=5 Tax=cellul...   207   4e-52
UniRef50_Q95TC1 GH03781p n=13 Tax=cellular organisms RepID=Q95TC...   206   8e-52
UniRef50_Q7KV94 CG16758, isoform B n=33 Tax=cellular organisms R...   205   2e-51
UniRef50_D2MQ16 Purine nucleoside phosphorylase I, inosine and g...   204   2e-51
UniRef50_A9KIZ4 Inosine guanosine and xanthosine phosphorylase f...   204   3e-51
UniRef50_C1AAZ0 Purine nucleoside phosphorylase n=1 Tax=Gemmatim...   203   6e-51
UniRef50_P00491 Purine nucleoside phosphorylase n=19 Tax=Coeloma...   202   1e-50
UniRef50_Q23U21 Purine nucleoside phosphorylase n=1 Tax=Tetrahym...   202   1e-50
UniRef50_P23492 Purine nucleoside phosphorylase n=47 Tax=Metazoa...   202   1e-50
UniRef50_UPI0000522022 PREDICTED: similar to nucleoside phosphor...   200   4e-50
UniRef50_C3ZRV1 Putative uncharacterized protein (Fragment) n=1 ...   199   8e-50
UniRef50_C4QLI3 Purine nucleoside phosphorylase n=2 Tax=Schistos...   198   1e-49
UniRef50_Q9BMI9 Purine-nucleoside phosphorylase n=1 Tax=Schistos...   198   2e-49
UniRef50_D2QX64 Purine nucleoside phosphorylase I, inosine and g...   198   2e-49
UniRef50_B0VG85 Purine nucleoside phosphorylase 1 (Purine nucleo...   198   2e-49
UniRef50_D1B5G3 Inosine guanosine and xanthosine phosphorylase f...   197   2e-49
UniRef50_Q6MGR6 Pnp protein n=1 Tax=Bdellovibrio bacteriovorus R...   196   6e-49
UniRef50_C3J8Q8 Purine nucleoside phosphorylase I, inosine and g...   196   1e-48
UniRef50_B9WDS7 Purine nucleoside phosphorylase, putative n=14 T...   194   3e-48
UniRef50_D0MFN5 Inosine guanosine and xanthosine phosphorylase f...   193   5e-48
UniRef50_D0LL71 Purine nucleoside phosphorylase I, inosine and g...   192   8e-48
UniRef50_C9LGF9 Purine nucleoside phosphorylase I, inosine and g...   192   9e-48
UniRef50_C3FBK6 Purine nucleoside phosphorylase I, inosine and g...   192   1e-47
UniRef50_A7HJP7 Purine nucleoside phosphorylase I, inosine and g...   191   3e-47
UniRef50_A8PXS8 Purine nucleoside phosphorylase I, inosine and g...   190   4e-47
UniRef50_Q5YBA4 Purine nucleoside phosphorylase n=2 Tax=Singapor...   190   4e-47
UniRef50_B6YR86 Purine-nucleoside phosphorylase n=1 Tax=Candidat...   190   5e-47
UniRef50_D1Y3S3 Purine nucleoside phosphorylase I, inosine and g...   190   5e-47
UniRef50_B2KC58 Inosine guanosine and xanthosine phosphorylase f...   190   6e-47
UniRef50_A9G8Q6 DeoD protein n=8 Tax=Bacteria RepID=A9G8Q6_SORC5      189   1e-46
UniRef50_C7MNU9 Inosine guanosine and xanthosine phosphorylase f...   188   1e-46
UniRef50_A3ZZ29 Purine nucleoside phosphorylase n=1 Tax=Blastopi...   188   2e-46
UniRef50_C5EQ75 Purine nucleoside phosphorylase I n=1 Tax=Clostr...   187   3e-46
UniRef50_C8V0B3 Purine nucleoside phosphorylase I, inosine and g...   187   4e-46
UniRef50_C0BWU4 Putative uncharacterized protein n=1 Tax=Clostri...   187   4e-46
UniRef50_B9XJR6 Inosine guanosine and xanthosine phosphorylase f...   186   9e-46
UniRef50_A7VBG8 Putative uncharacterized protein n=2 Tax=Clostri...   186   1e-45
UniRef50_B4D4P3 Inosine guanosine and xanthosine phosphorylase f...   185   1e-45
UniRef50_Q1NL01 Inosine guanosine and xanthosine phosphorylase:P...   185   2e-45
UniRef50_A9URE9 Predicted protein n=1 Tax=Monosiga brevicollis R...   184   3e-45
UniRef50_B7A7P1 Inosine guanosine and xanthosine phosphorylase f...   183   5e-45
UniRef50_Q3B5L6 Purine nucleoside phosphorylase I, inosine and g...   182   7e-45
UniRef50_C1C0Q7 Purine nucleoside phosphorylase n=2 Tax=Caligus ...   181   3e-44
UniRef50_A7S700 Predicted protein n=3 Tax=cellular organisms Rep...   180   5e-44
UniRef50_A4CJ72 Purine nucleoside phosphorylase n=15 Tax=Bactero...   180   5e-44
UniRef50_Q05788 Purine nucleoside phosphorylase n=10 Tax=Sacchar...   177   3e-43
UniRef50_Q311R2 Inosine guanosine and xanthosine phosphorylase n...   176   6e-43
UniRef50_C7LVA5 Inosine guanosine and xanthosine phosphorylase f...   175   1e-42
UniRef50_B1GZW7 Purine nucleoside phosphorylase n=1 Tax=uncultur...   174   4e-42
UniRef50_B6K0G6 Purine nucleoside phosphorylase n=1 Tax=Schizosa...   174   4e-42
UniRef50_B8ICG2 Purine nucleotide phosphorylase n=28 Tax=Alphapr...   173   6e-42
UniRef50_A9BH77 Purine nucleoside phosphorylase I, inosine and g...   171   3e-41
UniRef50_C7NVB1 Inosine guanosine and xanthosine phosphorylase f...   169   6e-41
UniRef50_B3QTH8 Inosine guanosine and xanthosine phosphorylase f...   169   9e-41
UniRef50_B8J4B5 Inosine guanosine and xanthosine phosphorylase f...   169   1e-40
UniRef50_Q9UTG1 Putative purine nucleoside phosphorylase n=4 Tax...   168   2e-40
UniRef50_Q2CJ93 Purine nucleoside phosphorylase n=1 Tax=Oceanico...   167   4e-40
UniRef50_B4MDV7 GJ18292 n=4 Tax=Drosophila RepID=B4MDV7_DROVI         166   6e-40
UniRef50_D2QX63 Inosine guanosine and xanthosine phosphorylase f...   164   3e-39
UniRef50_B7GAT6 Predicted protein (Fragment) n=2 Tax=Bacillariop...   162   2e-38
UniRef50_C5NWB5 Purine nucleoside phosphorylase 1 n=1 Tax=Gemell...   161   2e-38
UniRef50_B9ZYX1 Nucleoside phosphorylase n=1 Tax=Dicyema japonic...   161   3e-38
UniRef50_Q11M20 Inosine guanosine and xanthosine phosphorylase f...   159   9e-38
UniRef50_C5P2F4 Purine nucleoside phosphorylase, putative n=2 Ta...   158   2e-37
UniRef50_Q3A2Z8 Xanthosine phosphorylase n=1 Tax=Pelobacter carb...   158   2e-37
UniRef50_P46862 Purine nucleoside phosphorylase n=79 Tax=Actinom...   156   7e-37
UniRef50_Q2S0P3 Purine nucleoside phosphorylase n=1 Tax=Saliniba...   156   9e-37
UniRef50_D2L8K6 Inosine guanosine and xanthosine phosphorylase f...   155   1e-36
UniRef50_P81989 Purine nucleoside phosphorylase n=7 Tax=Actinoba...   152   2e-35
UniRef50_B0D4C6 Predicted protein n=3 Tax=Agaricales RepID=B0D4C...   149   7e-35
UniRef50_Q28ZG3 GA14805 n=2 Tax=pseudoobscura subgroup RepID=Q28...   141   3e-32
UniRef50_D1BYW2 Purine nucleotide phosphorylase n=6 Tax=Actinomy...   138   2e-31
UniRef50_C5C9E7 Purine nucleotide phosphorylase n=3 Tax=Actinomy...   135   1e-30
UniRef50_Q7URV0 Purine nucleoside phosphorylase I n=1 Tax=Rhodop...   135   2e-30
UniRef50_D2VAE0 Purine phosphorylase family protein n=1 Tax=Naeg...   135   2e-30
UniRef50_Q1K0Y4 Inosine guanosine and xanthosine phosphorylase n...   135   2e-30
UniRef50_B9KXK8 Purine nucleoside phosphorylase n=2 Tax=Thermomi...   134   4e-30
UniRef50_Q83H43 Purine nucleoside phosphorylase n=3 Tax=Trophery...   134   5e-30
UniRef50_C4FCF5 Putative uncharacterized protein n=2 Tax=Collins...   132   9e-30
UniRef50_C7MEB8 Purine nucleotide phosphorylase n=2 Tax=Micrococ...   131   2e-29
UniRef50_A2FHY6 Inosine guanosine and xanthosine phosphorylase f...   127   5e-28
UniRef50_B9CNR2 Purine nucleoside phosphorylase 1 n=2 Tax=Atopob...   127   5e-28
UniRef50_B3RV47 Putative uncharacterized protein n=1 Tax=Trichop...   126   6e-28
UniRef50_UPI00016C3D31 inosine guanosine and xanthosine phosphor...   125   1e-27
UniRef50_D0JB48 Purine nucleoside phosphorylase n=2 Tax=Blattaba...   124   4e-27
UniRef50_Q2S4Q1 Purine nucleoside phosphorylase I, inosine and g...   123   8e-27
UniRef50_Q9RIJ1 Purine nucleoside phosphorylase homolog (Fragmen...   116   1e-24
UniRef50_C3ZRU9 Putative uncharacterized protein n=1 Tax=Branchi...   115   1e-24
UniRef50_A8B9X8 Purine nucleoside phosphorylase lateral transfer...   115   1e-24
UniRef50_Q9W1K6 CG18128 n=7 Tax=melanogaster group RepID=Q9W1K6_...   114   4e-24
UniRef50_Q5C0P1 SJCHGC05230 protein (Fragment) n=1 Tax=Schistoso...   109   1e-22
UniRef50_Q0CL04 Purine nucleoside phosphorylase n=1 Tax=Aspergil...   107   3e-22
UniRef50_A2VPA1 Purine nucleoside phosphorylase deoD n=1 Tax=Myc...   104   4e-21
UniRef50_C1YKP8 Inosine guanosine and xanthosine phosphorylase f...    95   3e-18
UniRef50_UPI0001926077 PREDICTED: similar to nucleoside phosphor...    94   3e-18
UniRef50_A6GFX4 Purine nucleoside phosphorylase n=1 Tax=Plesiocy...    92   2e-17
UniRef50_A7BDZ0 Putative uncharacterized protein n=1 Tax=Actinom...    89   2e-16
UniRef50_UPI0000D5796F PREDICTED: similar to purine nucleoside p...    88   3e-16
UniRef50_B5Y8G4 Methylthioadenosine phosphorylase n=1 Tax=Coprot...    86   2e-15
UniRef50_B0K2V3 Purine phosphorylase, family 2 n=10 Tax=Thermoan...    86   2e-15
UniRef50_C2KQL7 Possible purine-nucleoside phosphorylase n=2 Tax...    85   2e-15
UniRef50_Q465I0 Methylthioadenosine phosphorylase n=4 Tax=Methan...    84   6e-15
UniRef50_C0QPX3 Methylthioadenosine phosphorylase n=6 Tax=Aquifi...    81   3e-14
UniRef50_O27633 Methylthioadenosine phosphorylase n=7 Tax=Archae...    80   9e-14
UniRef50_UPI0000E4A236 PREDICTED: similar to GTP-binding protein...    79   1e-13
UniRef50_B9K7V5 Purine nucleoside phosphorylase n=1 Tax=Thermoto...    78   4e-13
UniRef50_Q0W2D2 Putative purine phosphorylase (Family 2) n=1 Tax...    78   4e-13
UniRef50_Q1NY44 Methylthioadenosine phosphorylase n=2 Tax=delta ...    75   3e-12
UniRef50_O57865 Uncharacterized protein PH0125 n=36 Tax=Archaea ...    75   4e-12
UniRef50_C0W9U9 Purine nucleoside phosphorylase n=1 Tax=Acidamin...    74   6e-12
UniRef50_Q60367 Uncharacterized protein MJ0060 n=11 Tax=Methanoc...    73   8e-12
UniRef50_A3TNF6 Methylthioadenosine phosphorylase n=1 Tax=Janiba...    72   2e-11
UniRef50_D2RKT9 Purine or other phosphorylase family 1 n=1 Tax=A...    71   4e-11
UniRef50_Q87ZC3 Probable S-methyl-5'-thioadenosine phosphorylase...    69   2e-10
UniRef50_Q18KQ3 5'-methylthioadenosine phosphorylase MtaP n=4 Ta...    68   3e-10
UniRef50_B1I2E1 Methylthioadenosine phosphorylase n=33 Tax=cellu...    68   4e-10
UniRef50_Q5Z1K2 Putative methylthioadenosine phosphorylase n=4 T...    67   8e-10
UniRef50_C0W926 Purine-nucleoside phosphorylase n=1 Tax=Actinomy...    67   8e-10
UniRef50_C8R2U4 Methylthioadenosine phosphorylase n=1 Tax=Desulf...    67   9e-10
UniRef50_Q11FN7 Methylthioadenosine phosphorylase n=1 Tax=Chelat...    66   1e-09
UniRef50_Q2LVG5 Phosphorylase family 2 protein n=1 Tax=Syntrophu...    65   2e-09
UniRef50_B5ICA6 Phosphorylases family 2 n=2 Tax=Aciduliprofundum...    65   2e-09
UniRef50_Q2FR33 Methylthioadenosine phosphorylase n=1 Tax=Methan...    65   3e-09
UniRef50_Q13126 S-methyl-5'-thioadenosine phosphorylase n=55 Tax...    65   3e-09
UniRef50_A0L8V4 Methylthioadenosine phosphorylase n=1 Tax=Magnet...    64   5e-09
UniRef50_C5EEL8 Purine nucleoside phosphorylase n=1 Tax=Clostrid...    64   5e-09
UniRef50_Q7ZV22 Methylthioadenosine phosphorylase n=20 Tax=Metaz...    62   2e-08
UniRef50_Q21JS6 Methylthioadenosine phosphorylase n=1 Tax=Saccha...    62   2e-08
UniRef50_Q1PVD3 Similar to 5'-methylthioadenosine phosphorylase ...    62   2e-08
UniRef50_O28486 Methylthioadenosine phosphorylase (MtaP) n=1 Tax...    62   2e-08
UniRef50_B3T2V4 Putative phosphorylase family 2 n=2 Tax=environm...    62   3e-08
UniRef50_A9B0Q9 Purine phosphorylase family 2 n=1 Tax=Herpetosip...    62   3e-08
UniRef50_Q47F96 Methylthioadenosine phosphorylase n=7 Tax=Betapr...    62   3e-08
UniRef50_Q4P1A5 Putative uncharacterized protein n=1 Tax=Ustilag...    62   3e-08
UniRef50_Q16MW6 Methylthioadenosine phosphorylase n=6 Tax=Neopte...    61   3e-08
UniRef50_C6DE56 Methylthioadenosine phosphorylase n=1 Tax=Pectob...    61   4e-08
UniRef50_A7BPC6 Purine phosphorylase, family 2 n=2 Tax=Gammaprot...    61   4e-08
UniRef50_B4U6Q8 Purine phosphorylase family 2 n=2 Tax=Aquificace...    60   6e-08
UniRef50_C7LA98 FI12502p (Fragment) n=14 Tax=Drosophila RepID=C7...    60   7e-08
UniRef50_A0B8I0 Methylthioadenosine phosphorylase n=1 Tax=Methan...    60   1e-07
UniRef50_B1ZY09 Purine phosphorylase family 2 n=2 Tax=Opitutacea...    60   1e-07
UniRef50_Q5KPU2 Glutamate biosynthesis-related protein, putative...    60   1e-07
UniRef50_Q3ZZT2 Methylthioadenosine phosphorylase n=7 Tax=cellul...    59   2e-07
UniRef50_B5YKP5 S-methyl-5-thioadenosine phosphorylase n=1 Tax=T...    59   2e-07
UniRef50_Q0SDK3 Probable S-methyl-5-thioadenosine phosphorylase ...    59   2e-07
UniRef50_C1HCE7 Purine nucleoside phosphorylase n=1 Tax=Paracocc...    59   3e-07
UniRef50_A3DD28 Methylthioadenosine phosphorylase n=7 Tax=Clostr...    58   3e-07
UniRef50_B0DVC8 Predicted protein n=3 Tax=Basidiomycota RepID=B0...    58   4e-07
UniRef50_UPI000038263C COG0005: Purine nucleoside phosphorylase ...    58   4e-07
UniRef50_B4CZS2 Methylthioadenosine phosphorylase n=1 Tax=Chthon...    57   7e-07
UniRef50_D1A6L7 Methylthioadenosine phosphorylase n=16 Tax=Actin...    57   8e-07
UniRef50_Q0BRD3 5'-methylthioadenosine phosphorylase n=113 Tax=c...    57   8e-07
UniRef50_B1GZW8 S-methyl-5'-thioadenosine phosphorylase n=1 Tax=...    56   1e-06
UniRef50_Q07938 Multicopy enhancer of UAS2 n=12 Tax=Saccharomyce...    56   1e-06
UniRef50_B5JG81 Phosphorylases family 2 n=1 Tax=Verrucomicrobiae...    55   2e-06
UniRef50_Q1CZV1 Phosphorylase, family 2 n=5 Tax=Myxococcaceae Re...    55   2e-06
UniRef50_A4AL37 5'-methylthioadenosine phosphorylase n=3 Tax=Act...    55   2e-06
UniRef50_D1J9Q0 Putative uncharacterized protein n=2 Tax=uncultu...    55   3e-06
UniRef50_D1YZM1 5'-methylthioadenosine phosphorylase n=1 Tax=Met...    55   3e-06
UniRef50_D2V2R7 5'-methylthioadenosine phosphorylase n=1 Tax=Nae...    55   4e-06
UniRef50_B3PJG7 Methylthioadenosine phosphorylase n=1 Tax=Cellvi...    54   6e-06
UniRef50_C4Q4X0 Methylthioadenosine phosphorylase, putative n=1 ...    54   7e-06
UniRef50_A9A3N5 Methylthioadenosine phosphorylase n=4 Tax=Archae...    53   1e-05
UniRef50_A9GWF6 5'-methyl-5-thioadenosine phosphorylase n=1 Tax=...    53   1e-05
UniRef50_A9BDU8 5'-methylthioadenosine phosphorylase n=13 Tax=Cy...    53   1e-05
UniRef50_B7RUB3 Phosphorylases family 2 n=1 Tax=marine gamma pro...    53   1e-05
UniRef50_A0YHC5 Methylthioadenosine phosphorylase n=1 Tax=marine...    53   1e-05
UniRef50_B9KZC3 Methylthioadenosine phosphorylase n=2 Tax=Bacter...    52   2e-05
UniRef50_B8P408 Predicted protein n=2 Tax=Agaricomycetes RepID=B...    52   2e-05
UniRef50_C1SHM5 Purine nucleoside phosphorylase n=1 Tax=Denitrov...    52   2e-05
UniRef50_B8KGW0 Purine phosphorylase, family 2 n=1 Tax=gamma pro...    52   2e-05
UniRef50_Q9RKG9 Putative phosphorylase n=1 Tax=Streptomyces coel...    51   5e-05
UniRef50_B5EMB0 Methylthioadenosine phosphorylase n=15 Tax=Prote...    51   5e-05
UniRef50_A3EWJ6 Methylthioadenosine phosphorylase n=2 Tax=Leptos...    50   9e-05
UniRef50_C9ZU87 Methylthioadenosine phosphorylase, putative n=8 ...    50   9e-05
UniRef50_A4U101 Purine phosphorylase, family 2 n=4 Tax=Proteobac...    50   1e-04
UniRef50_D1C2Y0 Methylthioadenosine phosphorylase n=2 Tax=Bacter...    49   1e-04
UniRef50_Q1H1A2 Methylthioadenosine phosphorylase n=3 Tax=Bacter...    49   3e-04
UniRef50_Q0F2U5 Purine nucleoside phosphorylase n=1 Tax=Mariprof...    48   4e-04
UniRef50_Q67R93 Methylthioadenosine phosphorylase n=1 Tax=Symbio...    48   4e-04
UniRef50_C6HVW5 Methylthioadenosine phosphorylase n=1 Tax=Leptos...    47   7e-04
UniRef50_B0TI52 Purine nucleoside phosphorylase n=8 Tax=Clostrid...    47   7e-04
UniRef50_A2SSB6 Methylthioadenosine phosphorylase n=2 Tax=Methan...    47   7e-04
UniRef50_P74469 Sll0135 protein n=67 Tax=cellular organisms RepI...    47   7e-04
UniRef50_Q87BR7 Probable S-methyl-5'-thioadenosine phosphorylase...    47   8e-04
UniRef50_UPI000187D203 hypothetical protein MPER_09068 n=1 Tax=M...    47   0.001
UniRef50_A7I6C4 Purine phosphorylase, family 2 n=2 Tax=Genera in...    47   0.001
UniRef50_D0NYY4 Putative uncharacterized protein n=1 Tax=Phytoph...    46   0.001
UniRef50_C3Y9W3 Putative uncharacterized protein n=1 Tax=Branchi...    46   0.001
UniRef50_UPI000038E4F5 5''''-methylthioadenosine phosphorylase I...    46   0.002
UniRef50_C1C2B0 S-methyl-5-thioadenosine phosphorylase n=2 Tax=C...    46   0.002
UniRef50_UPI00016A8371 5''''-methylthioadenosine phosphorylase n...    45   0.002
UniRef50_Q7TP15 Cc1-6 n=9 Tax=Coelomata RepID=Q7TP15_RAT               44   0.005
UniRef50_C5KDS7 Methylthioadenosine/purine nucleoside phosphoryl...    44   0.005
UniRef50_A4X3Q9 Methylthioadenosine phosphorylase n=8 Tax=Actino...    44   0.006
UniRef50_C0W509 Possible purine-nucleoside phosphorylase n=1 Tax...    44   0.006
UniRef50_A8RJ25 Putative uncharacterized protein n=1 Tax=Clostri...    44   0.007
UniRef50_Q2RHE2 Purine phosphorylase, family 2 n=1 Tax=Moorella ...    44   0.008
UniRef50_Q09816 Uncharacterized protein C16C9.02c n=49 Tax=cellu...    42   0.019
UniRef50_UPI0001C31DF7 S-methyl-5''''-thioadenosine phosphorylas...    42   0.020
UniRef50_C5TP90 Methylthioadenosine phosphorylase n=5 Tax=Neisse...    42   0.022
UniRef50_A4IXW9 Phosphorylase family 2/alpha-beta hydrolase fold...    40   0.062

>UniRef50_P45563 Xanthosine phosphorylase n=57 Tax=cellular organisms
           RepID=XAPA_ECOLI
          Length = 277

 Score =  570 bits (1468), Expect = e-161,   Method: Compositional matrix adjust.
 Identities = 277/277 (100%), Positives = 277/277 (100%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS
Sbjct: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS
Sbjct: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG
Sbjct: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
           FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM
Sbjct: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA
Sbjct: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277


>UniRef50_B5R3U9 Xanthosine phosphorylase n=53 Tax=Enterobacteriaceae
           RepID=B5R3U9_SALEP
          Length = 307

 Score =  512 bits (1318), Expect = e-144,   Method: Compositional matrix adjust.
 Identities = 246/277 (88%), Positives = 258/277 (93%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           M    FSHNP +CIDII  +KP FTPRVAFILGSGLGALADQIE+AVAISYEKLPGFPVS
Sbjct: 31  MPHALFSHNPEYCIDIIHAHKPAFTPRVAFILGSGLGALADQIEDAVAISYEKLPGFPVS 90

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           TVHGHAGELVLGHL GVPV CMKGRGHFYEGRGM +MTDAIRT KLLGCE+LFCTNAAGS
Sbjct: 91  TVHGHAGELVLGHLAGVPVACMKGRGHFYEGRGMAVMTDAIRTLKLLGCEVLFCTNAAGS 150

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           LRPEVG GSLVAL DHINTMPGTPMVG NDDR+G+RFFSLANAYDA+YRA+LQ VA EEG
Sbjct: 151 LRPEVGPGSLVALSDHINTMPGTPMVGPNDDRYGDRFFSLANAYDADYRAMLQSVAAEEG 210

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
           FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHC LKVVAVSAITN+
Sbjct: 211 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCGLKVVAVSAITNL 270

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           AEGL DVKLSHAQTLAAAELS+QNFINLICGFLRK+A
Sbjct: 271 AEGLGDVKLSHAQTLAAAELSRQNFINLICGFLRKLA 307


>UniRef50_Q472Z5 Purine nucleotide phosphorylase:Inosine guanosine and xanthosine
           phosphorylase n=1 Tax=Ralstonia eutropha JMP134
           RepID=Q472Z5_RALEJ
          Length = 287

 Score =  290 bits (742), Expect = 4e-77,   Method: Compositional matrix adjust.
 Identities = 151/264 (57%), Positives = 189/264 (71%)

Query: 14  IDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH 73
           +  I+ +  +F P++  ILGSGLG LA  IENA+AI Y  LPGFP S V GHAGE+VLG 
Sbjct: 19  VQRIRQHVGEFRPQIGLILGSGLGGLARAIENAIAIPYAALPGFPQSLVEGHAGEVVLGR 78

Query: 74  LQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVAL 133
           L GV ++CM+GR HFYEG G T MT A+RT K +GC+ LF T AAGSL PE+  G LVA+
Sbjct: 79  LGGVELMCMRGRQHFYEGHGTTGMTQAVRTMKRMGCDRLFVTCAAGSLHPELEPGRLVAI 138

Query: 134 KDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPG 193
           KDHIN +PG P++G NDD+ G RF S+ANAYD   R  LQ VA+  G P  EGV+V++ G
Sbjct: 139 KDHINLLPGNPLIGPNDDQIGPRFCSMANAYDTVLRQGLQDVAQALGLPWAEGVYVAFSG 198

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQ 253
           P FETAAEIRMMQ+IGGDVVGMS VPEVISARHC L+V+A++ ITN+ EG+ +  LSH  
Sbjct: 199 PTFETAAEIRMMQVIGGDVVGMSTVPEVISARHCGLRVLAIACITNLGEGIGNEVLSHEL 258

Query: 254 TLAAAELSKQNFINLICGFLRKIA 277
           TL    ++  +   LI G+  + A
Sbjct: 259 TLQYGSMALVDLQRLIVGWFEQQA 282


>UniRef50_B6J4B4 Xanthosine phosphorylase n=8 Tax=Gammaproteobacteria
           RepID=B6J4B4_COXB1
          Length = 273

 Score =  271 bits (693), Expect = 2e-71,   Method: Compositional matrix adjust.
 Identities = 126/258 (48%), Positives = 174/258 (67%)

Query: 17  IKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQG 76
           I+  +PDF P++A +LGSGLG LAD+IE    ISY +LPGF    + GHAG L LG ++G
Sbjct: 12  IRHRRPDFQPKLAIVLGSGLGDLADEIEEPTVISYHELPGFHKPNIEGHAGNLYLGKIKG 71

Query: 77  VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDH 136
           VPV C++GR H+YEG     +   IRT KLLGCE+   TNAAGSL   +  GSL+ + DH
Sbjct: 72  VPVACLRGRAHYYEGADNYAIKTMIRTMKLLGCEIWLATNAAGSLHQRIEPGSLLVINDH 131

Query: 137 INTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNF 196
           IN      +VG N+D FG RF  + +AYD++ RA L K+AK+   PL+EGV++   GP F
Sbjct: 132 INFQFNNVLVGPNEDDFGGRFIGMEDAYDSDLRAQLFKIAKQLQIPLSEGVYIGVLGPAF 191

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLA 256
           ET AEIR  +++G DVVGMS +PEVI ARHCD++V  +S ++N A GL+  K++H QTL 
Sbjct: 192 ETPAEIRAFRLLGADVVGMSTIPEVIVARHCDMRVAVISVVSNFAAGLTHEKVTHEQTLR 251

Query: 257 AAELSKQNFINLICGFLR 274
             +L+ ++   L+  F++
Sbjct: 252 GVKLATESLKQLVLAFIQ 269


>UniRef50_A5IBS6 Xanthosine phosphorylase n=5 Tax=Legionella RepID=A5IBS6_LEGPC
          Length = 279

 Score =  257 bits (656), Expect = 3e-67,   Method: Compositional matrix adjust.
 Identities = 122/269 (45%), Positives = 168/269 (62%), Gaps = 1/269 (0%)

Query: 10  PLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGEL 69
           P    + I+   P F P+V  +LGSGLG  A+++E+ VAI YEKLPGFP +TV GH G+L
Sbjct: 11  PHLAAEYIQKTCPSFKPKVGVVLGSGLGQFAEELEDTVAIEYEKLPGFPRTTVQGHGGKL 70

Query: 70  VLGHLQGVPVVCMKGRGHFYEG-RGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAG 128
           +LG+     V+C++GR H YE       +   +RT KLLGC+    TNA+GSL+ EVG G
Sbjct: 71  ILGYYGSTAVICLQGRAHTYESMENHEAVKTYVRTLKLLGCQYFIATNASGSLKEEVGPG 130

Query: 129 SLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVF 188
            L+ + DHIN  PG P+VG NDD FG RF+ L NAYD   R  L  +A+     L +GV+
Sbjct: 131 ELMLITDHINFQPGNPLVGPNDDEFGPRFYPLDNAYDITMRNALLDIAQRHSIKLHQGVY 190

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK 248
           +S  GPN+ETAAEIR  +++G D VGMS VPEV+ A HC L+V  ++ ITN A GL+   
Sbjct: 191 ISVLGPNYETAAEIRAFKLLGADAVGMSTVPEVLVANHCGLRVAVIATITNYATGLAKTS 250

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKIA 277
            SH   +  A  + +    LI  ++ +++
Sbjct: 251 HSHESVVKMASSAAEKLNTLIKQYILELS 279


>UniRef50_A7GSB0 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=114 Tax=Bacteria RepID=A7GSB0_BACCN
          Length = 273

 Score =  249 bits (636), Expect = 7e-65,   Method: Compositional matrix adjust.
 Identities = 122/252 (48%), Positives = 166/252 (65%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           TP+V  ILGSGLG LAD+IENAV + Y ++P FPVSTV GHAG+LV G LQGV VV M+G
Sbjct: 20  TPKVGLILGSGLGVLADEIENAVKVPYSEIPEFPVSTVEGHAGQLVFGTLQGVTVVAMQG 79

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H+YEG  M  +T  +R  K LG E +  TNAAG +      G L+ + DHIN M   P
Sbjct: 80  RFHYYEGYDMQKVTFPVRVMKELGVETVVVTNAAGGVNTSFEPGDLMLISDHINFMGHNP 139

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           ++G ND   G RF  ++ +Y  E R ++++VA+E    + EGV+V+  GP +ET AEIRM
Sbjct: 140 LIGPNDAEMGVRFPDMSESYTKELRVMVKQVAEELNIKVQEGVYVAMTGPVYETPAEIRM 199

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           ++ +GGD VGMS VPEVI ARH  +KV+ +S I+NMA G+ D  L H + +   E  K N
Sbjct: 200 LRTLGGDAVGMSTVPEVIVARHAGMKVLGISCISNMAAGILDQPLHHDEVIETTERVKAN 259

Query: 265 FINLICGFLRKI 276
           F+ L+   ++++
Sbjct: 260 FLALVKAIVKQM 271


>UniRef50_A0NS72 Purine nucleoside phosphorylase n=7 Tax=Alphaproteobacteria
           RepID=A0NS72_9RHOB
          Length = 269

 Score =  246 bits (628), Expect = 6e-64,   Method: Compositional matrix adjust.
 Identities = 125/264 (47%), Positives = 172/264 (65%), Gaps = 4/264 (1%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
           C DI++  + + + ++  ILGSGLGALA+++E+AV I Y  L  FPVSTV  H+ ELV G
Sbjct: 8   CADIVRAAR-EGSYKIGMILGSGLGALAEEVEDAVRIPYSHLTEFPVSTVTSHSSELVAG 66

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L GVPVV + GR H+YEG   T+M   + T K LGCE+L  TNAAGSLR EV  GS + 
Sbjct: 67  TLSGVPVVILSGRAHYYEGGDPTVMRTPVETLKELGCEILLATNAAGSLRQEVAPGSPML 126

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN     P++G  D++   RF  ++ AYDA+ RA ++KVA+E G P+ EGV++ + 
Sbjct: 127 ISDHINWSGMNPLIGEEDEK---RFLDMSTAYDADLRAAMKKVAEETGDPVAEGVYMWFS 183

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP+FET AEIRM + +G D VGMS VPEVI AR   ++V A+S ITN   G+    LSH 
Sbjct: 184 GPSFETPAEIRMAKTLGADAVGMSTVPEVIMARFLGMRVAAMSIITNYGAGMQTHALSHD 243

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           +T + A    +    L+  F+++I
Sbjct: 244 ETKSVALQGMERMKELVRAFVKEI 267


>UniRef50_Q65HU0 PunA n=9 Tax=Firmicutes RepID=Q65HU0_BACLD
          Length = 271

 Score =  246 bits (627), Expect = 7e-64,   Method: Compositional matrix adjust.
 Identities = 125/262 (47%), Positives = 165/262 (62%), Gaps = 1/262 (0%)

Query: 15  DIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL 74
           D IK+ K +  P V  ILGSGLG LAD+IE+AV I YE +P FPVSTV GHAG+LV+G L
Sbjct: 10  DYIKS-KTEIKPAVGLILGSGLGVLADEIEDAVRIKYEDIPDFPVSTVEGHAGQLVIGRL 68

Query: 75  QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALK 134
           + V VV M+GR HFYEG  M  +T  +R  K LG E L  TNAAG +      G L+ + 
Sbjct: 69  ENVQVVAMQGRFHFYEGYSMDKVTFPVRVMKELGIETLIVTNAAGGVNESFRPGDLMIIS 128

Query: 135 DHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGP 194
           DHIN M   P++G ND   G RF  +++AYD E R L +K A+E    + EGV+ +  GP
Sbjct: 129 DHINYMGTNPLIGPNDSSLGVRFPDMSSAYDKELRLLAKKTAEELNISVQEGVYTAVTGP 188

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQT 254
            +ET AE+R ++ IG D VGMS VPEVI A+H  L+V+ +S I+N A G+ D  LSH + 
Sbjct: 189 TYETPAEVRFLRTIGSDAVGMSTVPEVIVAKHAGLRVLGISCISNAAAGILDQPLSHDEV 248

Query: 255 LAAAELSKQNFINLICGFLRKI 276
           +   E  K +F+  +   + KI
Sbjct: 249 IEVTEKVKADFLRFVKAAVAKI 270


>UniRef50_P46354 Purine nucleoside phosphorylase 1 n=69 Tax=Bacteria
           RepID=PUNA_BACSU
          Length = 271

 Score =  245 bits (625), Expect = 1e-63,   Method: Compositional matrix adjust.
 Identities = 120/253 (47%), Positives = 167/253 (66%), Gaps = 1/253 (0%)

Query: 17  IKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQG 76
           IK   P+ +P++  ILGSGLG LAD+IEN V + YE +P FPVSTV GHAG+LVLG L+G
Sbjct: 12  IKQNLPE-SPKIGLILGSGLGILADEIENPVKLKYEDIPEFPVSTVEGHAGQLVLGTLEG 70

Query: 77  VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDH 136
           V V+ M+GR HFYEG  M  +T  +R  K LG E L  TNAAG +  E  AG L+ + DH
Sbjct: 71  VSVIAMQGRFHFYEGYSMEKVTFPVRVMKALGVEALIVTNAAGGVNTEFRAGDLMIITDH 130

Query: 137 INTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNF 196
           IN M   P++G N+  FG RF  +++AYD +  +L +K+AK+   P+ +GV+ +  GP++
Sbjct: 131 INFMGTNPLIGPNEADFGARFPDMSSAYDKDLSSLAEKIAKDLNIPIQKGVYTAVTGPSY 190

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLA 256
           ET AE+R ++ +G D VGMS VPEVI A H  ++V+ +S I+N A G+ D  LSH + + 
Sbjct: 191 ETPAEVRFLRTMGSDAVGMSTVPEVIVANHAGMRVLGISCISNAAAGILDQPLSHDEVME 250

Query: 257 AAELSKQNFINLI 269
             E  K  F+ L+
Sbjct: 251 VTEKVKAGFLKLV 263


>UniRef50_P77834 Purine nucleoside phosphorylase 1 n=41 Tax=Bacilli RepID=PUNA_BACST
          Length = 274

 Score =  244 bits (622), Expect = 3e-63,   Method: Compositional matrix adjust.
 Identities = 118/253 (46%), Positives = 161/253 (63%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           +P++  ILGSGLG LAD+IE A+ I Y  +P FPVSTV GHAG+LV G L+G  VV M+G
Sbjct: 20  SPQIGLILGSGLGVLADEIEQAIKIPYSDIPNFPVSTVEGHAGQLVYGQLEGATVVVMQG 79

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H+YEG     +T  +R  K LG E L  TNAAG +      G L+ + DHIN M G P
Sbjct: 80  RFHYYEGYSFDKVTFPVRVMKALGVEQLIVTNAAGGVNESFEPGDLMIISDHINNMGGNP 139

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           ++G ND   G RF  ++ AY    R L + VA + G  + EGV+V+  GP +ET AEIRM
Sbjct: 140 LIGPNDSALGVRFPDMSEAYSKRLRQLAKDVANDIGLRVREGVYVANTGPAYETPAEIRM 199

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           ++++GGD VGMS VPEVI ARH  ++V+ +S I+NMA G+ D  L+H + +   E  K +
Sbjct: 200 IRVMGGDAVGMSTVPEVIVARHAGMEVLGISCISNMAAGILDQPLTHDEVIETTEKVKAD 259

Query: 265 FINLICGFLRKIA 277
           F+  +   +R +A
Sbjct: 260 FLRFVKAIVRNMA 272


>UniRef50_Q2B6A0 Purine nucleoside phosphorylase n=12 Tax=Bacilli RepID=Q2B6A0_9BACI
          Length = 273

 Score =  240 bits (612), Expect = 5e-62,   Method: Compositional matrix adjust.
 Identities = 116/251 (46%), Positives = 159/251 (63%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           TP++  ILGSGLG LAD+IE  V I Y ++P FPVSTV GHAG+LV G L GV  V M+G
Sbjct: 20  TPKIGLILGSGLGVLADEIEQPVKIPYNEIPDFPVSTVEGHAGQLVFGLLNGVQAVAMQG 79

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H+YEG     +T  +R  K LG E+L  TNAAG +      G L+ + DHIN M   P
Sbjct: 80  RFHYYEGYSFDKVTFPVRVMKELGVEILIVTNAAGGVNESFAPGDLMLISDHINNMGSNP 139

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           ++G ND + G RF  ++ AY  + R   +++A +    + EGV+V   GP +ET AE+RM
Sbjct: 140 LIGPNDSKLGVRFPDMSEAYSRDLRQQAREIAGKLNISIQEGVYVGNTGPTYETPAEVRM 199

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           ++ +GGD VGMS VPEVI ARH  LKV+ +S I+NMA G+ D  L+H + +   E  K N
Sbjct: 200 LRTMGGDAVGMSTVPEVIVARHAGLKVLGISCISNMAAGILDQPLNHEEVIETTEKVKAN 259

Query: 265 FINLICGFLRK 275
           F++ +   +R+
Sbjct: 260 FLSYVKELVRQ 270


>UniRef50_B1YM96 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=8 Tax=Bacteria RepID=B1YM96_EXIS2
          Length = 270

 Score =  239 bits (611), Expect = 6e-62,   Method: Compositional matrix adjust.
 Identities = 116/251 (46%), Positives = 161/251 (64%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P +  ILGSGLG LAD IEN +AI Y  +P FPVSTV GHAG+LV G L+G  VV M+GR
Sbjct: 20  PEIGLILGSGLGVLADDIENPIAIPYSDIPNFPVSTVEGHAGQLVFGTLEGKQVVAMQGR 79

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            HFYEG  M ++T  +R  K +G E L  TNAAG+       G L+ + DHIN     P+
Sbjct: 80  FHFYEGYSMEMVTFPVRVMKAIGVETLIVTNAAGACNEAFEPGDLMLITDHINFFGTNPL 139

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMM 205
           +G N D  G RF  ++  YDAE   L Q+ A E G  + +GV+    GP +ET AE+++ 
Sbjct: 140 IGKNVDEMGPRFPDMSKPYDAELLRLAQETADELGINVRQGVYFGNTGPTYETPAEVKLA 199

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNF 265
           +++GGDVVGMS VPEVI ARH D++V+ +S ++NMA G+ D  L H + +   E  + +F
Sbjct: 200 RLLGGDVVGMSTVPEVIVARHSDMRVLGISCVSNMAAGILDQPLHHDEVIETTERVRAHF 259

Query: 266 INLICGFLRKI 276
           ++L+ G ++K+
Sbjct: 260 LSLVRGSIKKM 270


>UniRef50_Q1IM44 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=2 Tax=cellular organisms RepID=Q1IM44_ACIBL
          Length = 280

 Score =  234 bits (598), Expect = 2e-60,   Method: Compositional matrix adjust.
 Identities = 115/252 (45%), Positives = 160/252 (63%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P VA +LGSGLG  A+++     I + ++P FPVST  GHAG LV+G+  G+ +  M+GR
Sbjct: 25  PNVAVVLGSGLGDFANELAQPSTIPFGEIPHFPVSTAIGHAGNLVIGNFVGLSLAVMQGR 84

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            HFYEG         +R    LG + +  TNAAG + P+ G G+LV ++DHIN M G+P+
Sbjct: 85  AHFYEGNTFAQAAFPMRVLHQLGVKAVVLTNAAGGINPQYGRGALVMVRDHINMMGGSPL 144

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMM 205
           +G NDDRFG RF  +  AYD EYR + +  AK    P  EG++ +  GP++ET AEI+M+
Sbjct: 145 IGPNDDRFGPRFPDMTYAYDREYRKIAEAEAKRLDIPYYEGIYAAMHGPSYETPAEIQML 204

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNF 265
             +G D+VGMS VPEVI ARH D++V+A+S +TNMA GLS   ++H + L      K  F
Sbjct: 205 ARMGADLVGMSTVPEVIVARHMDVRVLAISCVTNMAAGLSGEAINHEEVLETGRRVKDTF 264

Query: 266 INLICGFLRKIA 277
           + L+   L KIA
Sbjct: 265 LALLRAVLPKIA 276


>UniRef50_B9MKK7 Inosine guanosine and xanthosine phosphorylase family n=68
           Tax=Bacteria RepID=B9MKK7_ANATD
          Length = 272

 Score =  222 bits (566), Expect = 9e-57,   Method: Compositional matrix adjust.
 Identities = 111/262 (42%), Positives = 160/262 (61%), Gaps = 1/262 (0%)

Query: 15  DIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL 74
           + IK+  P+  P +A ILGSGLG+ AD +E  + I Y ++P FPVSTV GH G LV G +
Sbjct: 12  EFIKSKIPN-VPEIAIILGSGLGSFADTMEEKIEIKYSEIPHFPVSTVKGHKGNLVFGKV 70

Query: 75  QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALK 134
           +G  V+  +GR H YEG     +   +R   LLG + L  TNAAG + P +  G L+ +K
Sbjct: 71  KGREVLAFQGRFHLYEGYNAQEVVFGVRAAGLLGVKNLIVTNAAGGISPLLSPGDLMVIK 130

Query: 135 DHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGP 194
           DHIN     P +G   ++FGERFF +  AYD E     + V K+ G    EG++    GP
Sbjct: 131 DHINLSGENPAIGSEAEKFGERFFDMTYAYDREIIEKSKDVYKKNGVDYKEGIYAFLKGP 190

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQT 254
           ++ET +EIRM++I+G D VGMS V EVI+AR  ++KV  +S ITNMA G+ + KLSH + 
Sbjct: 191 SYETPSEIRMLKILGADAVGMSTVLEVIAARQMNIKVFGISCITNMAAGILEKKLSHEEV 250

Query: 255 LAAAELSKQNFINLICGFLRKI 276
           +  +++ ++ FI +I   +  I
Sbjct: 251 IEVSKMVEEKFIKIISDLIEII 272


>UniRef50_A3DEQ4 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=8 Tax=Firmicutes RepID=A3DEQ4_CLOTH
          Length = 275

 Score =  220 bits (561), Expect = 3e-56,   Method: Compositional matrix adjust.
 Identities = 108/245 (44%), Positives = 155/245 (63%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           TP +A +LGSGLG LAD+IEN V I Y+ +P FPV+TV GHAG+ V G L+   V+ MKG
Sbjct: 22  TPEIAIVLGSGLGPLADEIENKVEIDYKDVPNFPVTTVEGHAGKFVYGILENRRVIAMKG 81

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H YEG  ++ +   +R FK+LG   L  TNA+G +      G L+ +KDHI+    +P
Sbjct: 82  RFHHYEGYDVSQIVFPVRVFKMLGINNLIVTNASGGINRSFRPGDLMIIKDHISFFAPSP 141

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           + G N D FG RF  +  AY+ +   + +K A + G  + EGV+    GP +ET AEIR 
Sbjct: 142 LRGKNIDEFGLRFPDMCKAYNPKLVEICKKAASDVGVDVKEGVYAFTQGPMYETPAEIRA 201

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           + I+G D VGMS VPEVI+ARH ++ ++ +S ITNMA G+ D  L+H + +  A+ ++  
Sbjct: 202 LGILGADAVGMSTVPEVIAARHANMNILGISCITNMAAGILDQPLTHEEVMKTAKEAENK 261

Query: 265 FINLI 269
           F+ L+
Sbjct: 262 FVRLV 266


>UniRef50_B8HVY6 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Cyanothece sp. PCC 7425 RepID=B8HVY6_CYAP4
          Length = 275

 Score =  219 bits (557), Expect = 1e-55,   Method: Compositional matrix adjust.
 Identities = 110/255 (43%), Positives = 156/255 (61%), Gaps = 2/255 (0%)

Query: 15  DIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL 74
           + ++ Y+    P +  ILGSGLG+ A  ++ ++AI Y  +P FP  TV GH GEL+LG  
Sbjct: 13  EFLRQYQ--IMPDIWVILGSGLGSFASTLKKSLAIPYADIPHFPRPTVAGHGGELILGQC 70

Query: 75  QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALK 134
             + V  M+GR H+YEG  +  +T  IR   LLG + L  TNAAG L P+   G L+ + 
Sbjct: 71  GEIAVGVMQGRCHYYEGYSLEQVTFPIRVAGLLGVQRLVITNAAGGLNPDFVPGDLMLIT 130

Query: 135 DHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGP 194
           DHIN +   P+ G ++ RFG+RF  L  AY A YR L  K A E    L +GV+V+ PGP
Sbjct: 131 DHINLLGMNPLQGRHETRFGDRFLDLTQAYHATYRELALKAAAEMNLTLRQGVYVALPGP 190

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQT 254
           +FET AE+RM++ +GGD VGMS VPEVI  R   ++++ +S ITN+A G+S   ++H + 
Sbjct: 191 SFETPAEVRMLRALGGDAVGMSTVPEVIVGRQMGVQILGISCITNLAAGISSEPVNHTEV 250

Query: 255 LAAAELSKQNFINLI 269
           L   E   Q+F  L+
Sbjct: 251 LEVGEQVSQHFCELL 265


>UniRef50_C1F7J2 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Acidobacterium capsulatum ATCC 51196
           RepID=C1F7J2_ACIC5
          Length = 284

 Score =  215 bits (548), Expect = 1e-54,   Method: Compositional matrix adjust.
 Identities = 108/261 (41%), Positives = 159/261 (60%), Gaps = 1/261 (0%)

Query: 17  IKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQG 76
           I+   P   P+VA +LGSGLGA A  + N+  + + + P FPVS V GH+G + +G    
Sbjct: 17  IRKRSP-LQPKVAVVLGSGLGAFAGSLTNSKCMRFSEAPHFPVSNVQGHSGRIHIGQCGD 75

Query: 77  VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDH 136
            PV+ M+GR H YEG   + +   +R  K LG E +  TNAAG +R  +  G LV ++DH
Sbjct: 76  TPVLVMQGRVHAYEGYKPSQVAFPVRVMKQLGIEQVIVTNAAGGIREGLQPGELVLIEDH 135

Query: 137 INTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNF 196
           IN     P+ G+N++RFG RFF + NAY    R L   VA++ G  L EGV++   GP+F
Sbjct: 136 INLTGYNPLCGVNEERFGPRFFDMTNAYSPRLRKLAHSVAEQHGHSLKEGVYIGVLGPSF 195

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLA 256
           ET AEIR  + +G D+VGMS V EVI+ARH  L+V+ +S +TN+A GL + +L+H + L 
Sbjct: 196 ETPAEIRAFRSMGADLVGMSTVQEVIAARHMGLEVLGISCVTNLAAGLQNEELTHEEVLE 255

Query: 257 AAELSKQNFINLICGFLRKIA 277
             + ++     L+ G + ++A
Sbjct: 256 TGKRTEAQLTQLLQGVIPQMA 276


>UniRef50_A6BDL0 Putative uncharacterized protein n=1 Tax=Dorea longicatena DSM
           13814 RepID=A6BDL0_9FIRM
          Length = 270

 Score =  215 bits (547), Expect = 1e-54,   Method: Compositional matrix adjust.
 Identities = 108/264 (40%), Positives = 159/264 (60%), Gaps = 1/264 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
           C+  I+  K DF P  A ILGSGLG  A++I+    + Y  +  FPVSTV GH G+ V G
Sbjct: 8   CLKSIRE-KTDFKPEKAVILGSGLGDYAEKIKIEKIVKYTDIEDFPVSTVQGHKGQFVFG 66

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
           +++ VPVV M+GR H+YEG  M  +    R   ++G + +  TNAAG + P    G  + 
Sbjct: 67  YVEDVPVVLMQGRVHYYEGYPMQDVVLPTRLMGMMGAKKILLTNAAGGVNPSFRPGDFML 126

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           +KDHI T   +P++G N +  G RF  ++  Y  + + +++K AK+ G PL EGV+V   
Sbjct: 127 IKDHITTAVPSPLIGPNIEELGTRFPDMSEVYSKKLQDIIRKSAKDCGIPLQEGVYVQLT 186

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GPN+ET AEIRM++  G D VGMS   E ++ARH  ++V  +S ITNMA G+S+ KL+HA
Sbjct: 187 GPNYETPAEIRMVRSWGADAVGMSTACEAMAARHMGMEVCGISCITNMAAGVSNAKLNHA 246

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           +    A+   ++F  L+   +  I
Sbjct: 247 EVQETADRVAKDFEKLVTDVIAAI 270


>UniRef50_A6NWZ5 Putative uncharacterized protein n=1 Tax=Bacteroides capillosus
           ATCC 29799 RepID=A6NWZ5_9BACE
          Length = 274

 Score =  214 bits (545), Expect = 2e-54,   Method: Compositional matrix adjust.
 Identities = 108/262 (41%), Positives = 157/262 (59%)

Query: 15  DIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL 74
           + I++   DFTP+ A +LGSGLG + D +++ + + Y+++P F  ST  GH G+LV G+L
Sbjct: 13  EYIRSKIGDFTPKAAMVLGSGLGFMGDVVKDPIVVPYKEIPHFKASTAPGHKGQLVFGYL 72

Query: 75  QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALK 134
           +  PV  M+GR H YEG     ++ A+R  +LLG + L  TNAAG +R +  AG L+ + 
Sbjct: 73  EDKPVAVMQGRMHHYEGYSFEDVSYAVRVLRLLGADTLIVTNAAGCVRTDWQAGDLMLIT 132

Query: 135 DHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGP 194
           DHI     +P+ G N   FG RF   ++ Y    R L ++ A E G  L EGV+    GP
Sbjct: 133 DHIKMFSESPLRGENMPEFGVRFPDASSLYTPALRTLAREAAAELGIELREGVYFYCYGP 192

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQT 254
            +ET AE+R  +I+GGD VGMS  PEVI A HC ++V+  + ++NMA G+ D  LS  + 
Sbjct: 193 QYETPAEVRAARILGGDAVGMSTAPEVIVAGHCGMQVLGFTLLSNMAAGILDQPLSEQEV 252

Query: 255 LAAAELSKQNFINLICGFLRKI 276
           L AAE  K  F  L+   L+K+
Sbjct: 253 LDAAEACKDKFSRLVLACLKKL 274


>UniRef50_A5USV0 Inosine guanosine and xanthosine phosphorylase family n=19
           Tax=Bacteria RepID=A5USV0_ROSS1
          Length = 297

 Score =  214 bits (544), Expect = 3e-54,   Method: Compositional matrix adjust.
 Identities = 120/266 (45%), Positives = 157/266 (59%), Gaps = 9/266 (3%)

Query: 16  IIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQ 75
           II    P   PR+A ILGSGLG LAD +  +V I Y ++PGF    V GH GELV+G L 
Sbjct: 23  IIAARSP-IEPRIALILGSGLGDLADAVTESVTIPYTEIPGFVQPAVVGHRGELVIGLLA 81

Query: 76  GVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKD 135
           G PV  M+GR HFYEG  M  +T  +R    LGC  L  TNAAG L  +   G L+ + D
Sbjct: 82  GQPVAVMRGRFHFYEGHSMQQVTFPVRVLHALGCTALLATNAAGGLHADWRVGDLMLITD 141

Query: 136 HINTMPGT----PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSY 191
           HI  +PG     P+ G NDDR G RF  +  AYD   +A+ + VA E G  L EGV++  
Sbjct: 142 HI-FLPGLAGHHPLRGPNDDRLGPRFPPMVGAYDPTLQAVARAVAAELGIALREGVYMML 200

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VKLS 250
            GP FE++AE+RM + +G D VGMS  PEV+ ARH  ++ + +S ITN+A  L D    S
Sbjct: 201 SGPAFESSAELRMCRALGADAVGMSTAPEVVVARHMGMRCLGLSLITNLA--LPDGPPAS 258

Query: 251 HAQTLAAAELSKQNFINLICGFLRKI 276
           H + L A + ++  F  LICG L ++
Sbjct: 259 HQEVLDAGDAARPAFTALICGILARM 284


>UniRef50_A6GZM2 Purine-nucleoside phosphorylase n=3 Tax=Bacteroidetes
           RepID=A6GZM2_FLAPJ
          Length = 270

 Score =  214 bits (544), Expect = 4e-54,   Method: Compositional matrix adjust.
 Identities = 106/249 (42%), Positives = 151/249 (60%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           K +F+P    ILGSGLG   D I     + Y ++P FPVSTV GH G LV G +QG  +V
Sbjct: 15  KTNFSPEYGVILGSGLGNFTDDINIEYILPYSEIPNFPVSTVEGHKGALVFGTIQGKKIV 74

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
            M+GR HFYEG  M  +T  +R  K LG E L  +NA+G + P    GS++ +KDHIN M
Sbjct: 75  AMQGRFHFYEGYDMKQVTFPVRVMKYLGVEKLIVSNASGGVNPNYKVGSIILIKDHINMM 134

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAA 200
           P  P+ G ND+RFG RF +++  Y  +     +++A      + +GV++   GP +ET +
Sbjct: 135 PEHPLRGKNDERFGPRFVNMSEPYSRKMIVKAKEIASYLDIQVQDGVYLGLQGPTYETLS 194

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAEL 260
           E +M++ +G D VGMS VPEVI ARH +L+   +S IT+M    S   +SHA+ L AA+ 
Sbjct: 195 EYKMVKNVGADCVGMSTVPEVIVARHMNLECFGLSIITDMGNEASIETVSHAEVLQAAQK 254

Query: 261 SKQNFINLI 269
           ++ +  NLI
Sbjct: 255 AEPHVRNLI 263


>UniRef50_Q11C51 Inosine guanosine and xanthosine phosphorylase family n=10
           Tax=Alphaproteobacteria RepID=Q11C51_MESSB
          Length = 268

 Score =  212 bits (539), Expect = 1e-53,   Method: Compositional matrix adjust.
 Identities = 114/265 (43%), Positives = 159/265 (60%), Gaps = 3/265 (1%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            IDI+        PR+A +LGSGLGALAD++   V I Y  LPGFP+S V GHAGELV G
Sbjct: 4   TIDILIERLNGLAPRLAIVLGSGLGALADELTKPVHIPYADLPGFPLSGVSGHAGELVAG 63

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
           +   VPV+ + GR H+YE      M  A+     +G   +  TNAAGSL+ ++ AGS++ 
Sbjct: 64  YFGSVPVIMLAGRSHYYEHGNAAAMRPALEVLAGIGVTAIILTNAAGSLQVDMPAGSVML 123

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           ++DHIN     P++G   +    RF  ++ AYD + R  L++ A + G  L +GV++ + 
Sbjct: 124 VEDHINYSGMNPLIGEQSE---ARFVGMSAAYDRDLRDALERAASKAGETLHKGVYMWFS 180

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP+FET AEIRM +++G D VGMS VPEVI AR   L+V A S ITN+A GL   +LSH 
Sbjct: 181 GPSFETPAEIRMARMLGADAVGMSTVPEVILARFLGLRVAACSVITNLAAGLGAGELSHD 240

Query: 253 QTLAAAELSKQNFINLICGFLRKIA 277
           +T   A +       ++  F+R  A
Sbjct: 241 ETKDMAPVGGGKLAKILTQFMRDSA 265


>UniRef50_Q0TU47 Purine nucleoside phosphorylase n=7 Tax=Clostridium perfringens
           RepID=Q0TU47_CLOP1
          Length = 272

 Score =  210 bits (535), Expect = 4e-53,   Method: Compositional matrix adjust.
 Identities = 103/255 (40%), Positives = 152/255 (59%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           K  ++P++  +LG+GLG LA++IE A    Y  +P FPV T+ GH G L++G L G  V+
Sbjct: 17  KSKYSPKIGLVLGTGLGDLANEIEEAEYYRYMDIPNFPVPTIAGHEGTLIIGKLHGREVI 76

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
            MKGR H+YEG  M  +T  IR  KLLG E L  TN +G  +  + AG LV +++HIN  
Sbjct: 77  AMKGRCHYYEGHSMQRITLPIRVMKLLGVETLVVTNCSGQAKESIEAGDLVVIRNHINFT 136

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAA 200
              P+ G N   FGERF  LA  YD + R  ++ +AK+    L EGV+  + GP++ETA 
Sbjct: 137 GDNPLRGENLLEFGERFPDLAYPYDKDLREEVKNIAKDLDINLKEGVYAMFSGPSYETAV 196

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAEL 260
           E  M   +G DVVGMS VPEVI A HC +KV+  S +  +A   S+ +++H + +   + 
Sbjct: 197 ETLMAASLGADVVGMSTVPEVIVANHCGIKVLGFSGVPCLAAAYSEAEITHEEAMVNFQS 256

Query: 261 SKQNFINLICGFLRK 275
             +   +++  FL++
Sbjct: 257 ITEKCTSIVKEFLKR 271


>UniRef50_C7M8V2 Inosine guanosine and xanthosine phosphorylase family n=3
           Tax=Flavobacteriaceae RepID=C7M8V2_CAPOD
          Length = 275

 Score =  209 bits (533), Expect = 6e-53,   Method: Compositional matrix adjust.
 Identities = 108/259 (41%), Positives = 154/259 (59%)

Query: 16  IIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQ 75
           II++Y  + TP  A ILGSGL  L D++E    I Y  +P FP STV GH G+L+ G ++
Sbjct: 14  IIQSYITEHTPEFAIILGSGLNKLEDEVEVISEIKYNNIPNFPKSTVEGHKGKLIYGKIE 73

Query: 76  GVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKD 135
              V+ M GR H+YEG  M  +T  IR F  LG + L  +NA+G + P    G ++ ++D
Sbjct: 74  NRYVLMMAGRVHYYEGYTMQEVTFPIRVFAQLGIKRLIVSNASGGVNPNFSIGDVMVIRD 133

Query: 136 HINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPN 195
           HIN  P  P+ G N D FG RF  ++  Y       L+K+AK+    L +GV+V   GP+
Sbjct: 134 HINLFPEHPLRGKNLDLFGARFPDMSKPYSQAMITELEKIAKKHKIKLQKGVYVGLQGPS 193

Query: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL 255
           FET AE  M++I+GGD VGMS VPEVI ARH +++V A+S IT++        +SH + L
Sbjct: 194 FETPAEYGMVRILGGDAVGMSTVPEVIVARHQNMEVCALSVITDLGGPDISPDVSHEEVL 253

Query: 256 AAAELSKQNFINLICGFLR 274
            AA ++  N I L+   ++
Sbjct: 254 NAANIAMPNVILLVKNLIK 272


>UniRef50_C1TMH4 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002
           RepID=C1TMH4_9BACT
          Length = 272

 Score =  209 bits (532), Expect = 8e-53,   Method: Compositional matrix adjust.
 Identities = 108/253 (42%), Positives = 152/253 (60%)

Query: 24  FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
           FTP +A +LGSGLGALAD IEN + I YE++P +P+ST  GHAG LV G   G  VV M+
Sbjct: 18  FTPDIAVVLGSGLGALADAIENPIVIPYEEIPHWPMSTAPGHAGRLVAGSFCGKSVVAMQ 77

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           GR HFYEG  M  +   +R F   G      +NA+G +   +  G +V + DHIN M   
Sbjct: 78  GRLHFYEGYQMDQVVFPVRVFGRWGIPYFVASNASGGIGYGLVPGDMVLIHDHINLMGTN 137

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIR 203
           P++G N    GERF  ++ AYD +   + ++V++++G     GV+V++ GP++ET AEIR
Sbjct: 138 PLIGPNLSELGERFPDMSYAYDRDLLDIAEEVSRDKGITTRRGVYVAFTGPSYETPAEIR 197

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
           M + +G DVVGMS VPEVI AR   +KV AVS + N A G++   LS  + L     +  
Sbjct: 198 MARTLGADVVGMSTVPEVIVARQAGMKVFAVSCVANYAAGMTASALSEQEVLDEMGKAAG 257

Query: 264 NFINLICGFLRKI 276
               L+ G + K+
Sbjct: 258 KLTALVGGVIEKL 270


>UniRef50_A9KIE8 Inosine guanosine and xanthosine phosphorylase family n=20
           Tax=Bacteria RepID=A9KIE8_CLOPH
          Length = 286

 Score =  207 bits (526), Expect = 4e-52,   Method: Compositional matrix adjust.
 Identities = 103/257 (40%), Positives = 154/257 (59%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           K +F P VA +LGSGLG  ADQI+    + Y ++ GFPVSTV GH G  V G+++ VPVV
Sbjct: 24  KINFKPFVALVLGSGLGDYADQIKVEATLDYNEIEGFPVSTVAGHKGRFVFGYVEEVPVV 83

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
            M+GR H+YEG  M  +    R  K++G ++LF TNAAG +     AG  + + D I+  
Sbjct: 84  IMQGRVHYYEGYEMEDVVLPTRLMKMMGAKVLFLTNAAGGVNFNFKAGDFMLITDQISNF 143

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAA 200
             +P++G N +  G RF  ++  YD + R +++  AK+ G  L EGV++   GPNFE+ A
Sbjct: 144 VPSPLIGPNIEELGLRFCDMSEVYDKDLREVIRNSAKDIGMELQEGVYIQLSGPNFESPA 203

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAEL 260
           E++M +++G D VGMS   E I+A H  +K+  +S I+N+  G+++  LSH +    A+ 
Sbjct: 204 EVKMCRLLGADAVGMSTACEAITANHMGMKICGISCISNLGCGMTEEPLSHIEVQETADR 263

Query: 261 SKQNFINLICGFLRKIA 277
               F  LI   +R IA
Sbjct: 264 VAPLFKQLITTSIRNIA 280


>UniRef50_D0NTD2 Purine nucleoside phosphorylase 1 n=5 Tax=cellular organisms
           RepID=D0NTD2_PHYIN
          Length = 363

 Score =  207 bits (526), Expect = 4e-52,   Method: Compositional matrix adjust.
 Identities = 113/259 (43%), Positives = 150/259 (57%), Gaps = 9/259 (3%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P +  + GSGLG L+  +EN   I YE +P FP STV GHAGELV G L G+ VVCM+GR
Sbjct: 100 PLIGVVCGSGLGGLSKCLENQEVIKYEDIPQFPRSTVEGHAGELVFGDLDGIRVVCMRGR 159

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT-- 143
            H YEG  M      IR   LLG + L  TNAAG L P+   G L+ + DH+N MPG   
Sbjct: 160 FHCYEGYAMRETALPIRVMYLLGIKYLLVTNAAGGLNPDFNVGDLMIMNDHLN-MPGLSG 218

Query: 144 --PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF--PLTEGVFVSYPGPNFETA 199
             P++G ND RFG RF  L+N YD + + L  KVA++ G    + +GV+    GP +ET 
Sbjct: 219 QHPLIGPNDSRFGARFTPLSNCYDKKLQDLAVKVAEDLGLTHKVRKGVYCFVSGPTYETP 278

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA--EGLSDVKLSHAQTLAA 257
            E R ++++G D VGMS VPEVI A HC LKV+ +S ITN A   G      SH + L  
Sbjct: 279 TECRFLRLVGSDAVGMSTVPEVIVAAHCGLKVIGLSLITNKALFPGEEREAASHDEVLET 338

Query: 258 AELSKQNFINLICGFLRKI 276
            + ++ +    +   + +I
Sbjct: 339 VQATQNDIKRYVRDLIAEI 357


>UniRef50_Q95TC1 GH03781p n=13 Tax=cellular organisms RepID=Q95TC1_DROME
          Length = 356

 Score =  206 bits (523), Expect = 8e-52,   Method: Compositional matrix adjust.
 Identities = 112/260 (43%), Positives = 159/260 (61%), Gaps = 9/260 (3%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P++  I GSGLG+LAD I++     YEK+P FPVSTV GHAG LV+G L+G  V+ M+GR
Sbjct: 92  PKIGIICGSGLGSLADMIQDPKIFEYEKIPNFPVSTVEGHAGRLVVGTLEGATVMAMQGR 151

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM---PG 142
            HFYEG  +   +  +R  KL G E LF TNAAG + P    G ++ + DH+N +     
Sbjct: 152 FHFYEGYPLAKCSMPVRVMKLCGVEYLFATNAAGGINPRFAVGDIMLMHDHVNMLGFAGN 211

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNFETAA 200
           +P+ G ND RFG RF +L N+Y+ +      ++AK  G    +  GV+    GPN+ET A
Sbjct: 212 SPLQGPNDPRFGPRFPALVNSYNKDLINKAIEIAKAMGIESNIHVGVYSCLGGPNYETIA 271

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM-AEGLSDVK---LSHAQTLA 256
           E++ ++++G D VGMS V EVI+ARHCD+KV A S ITN  A   SD K    +H + +A
Sbjct: 272 ELKALRMMGVDAVGMSTVHEVITARHCDMKVFAFSLITNKCATEYSDKKDDEANHDEVMA 331

Query: 257 AAELSKQNFINLICGFLRKI 276
            A+  ++    L+   +R+I
Sbjct: 332 VAKNRQKACCELVSRLIREI 351


>UniRef50_Q7KV94 CG16758, isoform B n=33 Tax=cellular organisms RepID=Q7KV94_DROME
          Length = 353

 Score =  205 bits (521), Expect = 2e-51,   Method: Compositional matrix adjust.
 Identities = 112/260 (43%), Positives = 159/260 (61%), Gaps = 9/260 (3%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P++  I GSGLG+LAD I++     YEK+P FPVSTV GHAG LV+G L+G  V+ M+GR
Sbjct: 89  PKIGIICGSGLGSLADMIQDPKIFEYEKIPNFPVSTVEGHAGRLVVGTLEGATVMAMQGR 148

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM---PG 142
            HFYEG  +   +  +R  KL G E LF TNAAG + P    G ++ + DH+N +     
Sbjct: 149 FHFYEGYPLAKCSMPVRVMKLCGVEYLFATNAAGGINPRFAVGDIMLMHDHVNMLGFAGN 208

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNFETAA 200
           +P+ G ND RFG RF +L N+Y+ +      ++AK  G    +  GV+    GPN+ET A
Sbjct: 209 SPLQGPNDPRFGPRFPALVNSYNKDLINKAIEIAKAMGIESNIHVGVYSCLGGPNYETIA 268

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM-AEGLSDVK---LSHAQTLA 256
           E++ ++++G D VGMS V EVI+ARHCD+KV A S ITN  A   SD K    +H + +A
Sbjct: 269 ELKALRMMGVDAVGMSTVHEVITARHCDMKVFAFSLITNKCATEYSDKKDDEANHDEVMA 328

Query: 257 AAELSKQNFINLICGFLRKI 276
            A+  ++    L+   +R+I
Sbjct: 329 VAKNRQKACCELVSRLIREI 348


>UniRef50_D2MQ16 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Bulleidia extructa W1219 RepID=D2MQ16_9FIRM
          Length = 273

 Score =  204 bits (520), Expect = 2e-51,   Method: Compositional matrix adjust.
 Identities = 106/243 (43%), Positives = 151/243 (62%), Gaps = 5/243 (2%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +D I+T K D  P +  ILGSGLG L  Q+EN + I+Y+++PGF  +T   H GEL+ G
Sbjct: 11  ALDFIRT-KTDMVPEIGLILGSGLGTLVTQLENTITIAYQEIPGFLQTTNPSHKGELIFG 69

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L G  VVCM GR H YEG   + +   +R  KLLG ++L  TNAAG++      G ++ 
Sbjct: 70  FLNGKKVVCMSGRFHSYEGFSFSELVIPVRLLKLLGIQILMTTNAAGAVNESYRPGDVMI 129

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT--EGVFVS 190
           ++DH+     +PM G N++ FG RF+ ++  Y  E R   ++VA++  FPLT  EG +  
Sbjct: 130 IRDHLFFGIESPMRGFNEEDFGSRFYDVSTLYTPELREKAKEVARD--FPLTFHEGNYFF 187

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
             GP+FET AEIR ++I+GGD VGMS V E ++A HC LKV++ S  TNMA G+ +  LS
Sbjct: 188 MQGPHFETPAEIRAIRILGGDTVGMSTVTETLTAGHCGLKVLSFSVCTNMAAGILEQPLS 247

Query: 251 HAQ 253
             +
Sbjct: 248 DEE 250


>UniRef50_A9KIZ4 Inosine guanosine and xanthosine phosphorylase family n=6
           Tax=cellular organisms RepID=A9KIZ4_CLOPH
          Length = 274

 Score =  204 bits (518), Expect = 3e-51,   Method: Compositional matrix adjust.
 Identities = 103/256 (40%), Positives = 147/256 (57%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           K +  P+V  +LGSGLG L D IE    ISYE +P FP STV GH G LV G + GV ++
Sbjct: 18  KNNLKPKVGVVLGSGLGDLIDVIEEIEYISYEDIPNFPKSTVIGHQGRLVFGKINGVDIL 77

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
            M+GR H++EG  M  +   I   K LG E L  TNA G +  +   G+L+ + D IN +
Sbjct: 78  AMQGRFHYFEGYTMKEVAYPIFVMKQLGIEQLILTNACGGINTDFQPGTLMIINDFINLV 137

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAA 200
              P++G+ND+RFG RF  ++  Y  +     + +A E G    EGV+  + GP +ETAA
Sbjct: 138 SDNPLIGVNDERFGTRFPDMSEPYKLDLIDKAKNIANEMGIEYKEGVYAGFMGPYYETAA 197

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAEL 260
           EIRM++  G D VGMS VPE I+A +  + V+ +S ITNMA G+   K SH + +  A+ 
Sbjct: 198 EIRMIKNHGADAVGMSTVPETIAANYLGIDVLGISCITNMATGIQKHKHSHERVVETAQK 257

Query: 261 SKQNFINLICGFLRKI 276
           +  N    +   +  +
Sbjct: 258 ASVNLSKWVAKIIENM 273


>UniRef50_C1AAZ0 Purine nucleoside phosphorylase n=1 Tax=Gemmatimonas aurantiaca
           T-27 RepID=C1AAZ0_GEMAT
          Length = 277

 Score =  203 bits (516), Expect = 6e-51,   Method: Compositional matrix adjust.
 Identities = 108/252 (42%), Positives = 154/252 (61%), Gaps = 1/252 (0%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
            P    +LGSGLG LAD++ +AV I +  +PGFP +TV GHAG+L++G L   PVV + G
Sbjct: 23  APVCGIVLGSGLGGLADRLVDAVRIPFSHVPGFPTATVAGHAGQLLVGTLADRPVVALAG 82

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H YEG    +    +R    LG  +   +NAAG +R    AG L+ + DH+N M   P
Sbjct: 83  RFHMYEGHEAALAAFPVRVLHALGAPVYIASNAAGGVRRTFSAGDLMLIADHMNLMFRNP 142

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           ++G + +   ERF  +++ YD + RA ++  A+  G PL EGV+    GP +ET +E+RM
Sbjct: 143 LIG-STEPGDERFPDMSDPYDRDLRARMRAAAQVVGVPLHEGVYCGLLGPTYETPSEVRM 201

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           ++ +G D VGMS VPEVI AR   ++ VAVS ITN A GLS  KLSHA+ + A +    +
Sbjct: 202 LERMGVDAVGMSTVPEVIVARALGMRAVAVSCITNKAAGLSAEKLSHAEVMEAGKAVAGH 261

Query: 265 FINLICGFLRKI 276
           F  LI  F+R++
Sbjct: 262 FEALITEFVRQL 273


>UniRef50_P00491 Purine nucleoside phosphorylase n=19 Tax=Coelomata RepID=PNPH_HUMAN
          Length = 289

 Score =  202 bits (514), Expect = 1e-50,   Method: Compositional matrix adjust.
 Identities = 114/259 (44%), Positives = 152/259 (58%), Gaps = 9/259 (3%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P+VA I GSGLG L D++  A    Y ++P FP STV GHAG LV G L G   V M+GR
Sbjct: 25  PQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQGR 84

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG--- 142
            H YEG  +  +T  +R F LLG + L  TNAAG L P+   G ++ ++DHIN +PG   
Sbjct: 85  FHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHIN-LPGFSG 143

Query: 143 -TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE--EGFPLTEGVFVSYPGPNFETA 199
             P+ G ND+RFG+RF ++++AYD   R       K+  E   L EG +V   GP+FET 
Sbjct: 144 QNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETV 203

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN--MAEGLSDVKLSHAQTLAA 257
           AE R++Q +G D VGMS VPEVI ARHC L+V   S ITN  + +  S  K +H + LAA
Sbjct: 204 AECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAA 263

Query: 258 AELSKQNFINLICGFLRKI 276
            + + Q     +   +  I
Sbjct: 264 GKQAAQKLEQFVSILMASI 282


>UniRef50_Q23U21 Purine nucleoside phosphorylase n=1 Tax=Tetrahymena thermophila
           SB210 RepID=Q23U21_TETTH
          Length = 274

 Score =  202 bits (514), Expect = 1e-50,   Method: Compositional matrix adjust.
 Identities = 96/257 (37%), Positives = 152/257 (59%)

Query: 17  IKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQG 76
           IK+   +  P++A +LGSGLG   D+I++ + I Y  +P F  + V GHAG+L+ G ++G
Sbjct: 14  IKSKINNLNPQIAIVLGSGLGNFGDEIQDKIEIPYGDIPHFKKTQVIGHAGKLIFGKVEG 73

Query: 77  VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDH 136
           V +VCM+GR HFYEG  +      I+ FKLL  ++L  TNAAG L     +G L+ ++DH
Sbjct: 74  VEIVCMQGRYHFYEGHTIQECVFPIKVFKLLNIKILILTNAAGGLNDSYESGDLILIRDH 133

Query: 137 INTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNF 196
           IN +   P++GLN++ FG RF  ++  Y  +     +KV K+    +  G +    GPN+
Sbjct: 134 INMLGINPLIGLNEEEFGPRFPDMSITYTPQLLEKAKKVMKDLNISIKTGTYAGLRGPNY 193

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLA 256
           ET AE++M++    D+VG S V E I A H +++V+ +S ++NM  G+S   LSH + + 
Sbjct: 194 ETPAEVQMLRTFRADLVGASTVYEAIVASHMNIQVLGISCVSNMGAGISKTPLSHQEIID 253

Query: 257 AAELSKQNFINLICGFL 273
            +   K  F NL+   +
Sbjct: 254 VSNSIKSKFSNLVKNLI 270


>UniRef50_P23492 Purine nucleoside phosphorylase n=47 Tax=Metazoa RepID=PNPH_MOUSE
          Length = 289

 Score =  202 bits (514), Expect = 1e-50,   Method: Compositional matrix adjust.
 Identities = 114/264 (43%), Positives = 152/264 (57%), Gaps = 13/264 (4%)

Query: 23  DFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM 82
           ++ P+VA I GSGLG L   ++ A    Y ++P FP STV GHAG LV G L G   V M
Sbjct: 22  EYRPQVAVICGSGLGGLTAHLKEAQIFDYNEIPNFPQSTVQGHAGRLVFGLLNGRCCVMM 81

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
           +GR H YEG  ++ +T  +R F LLG E L  TNAAG L P    G ++ ++DHIN +PG
Sbjct: 82  QGRFHMYEGYSLSKVTFPVRVFHLLGVETLVVTNAAGGLNPNFEVGDIMLIRDHIN-LPG 140

Query: 143 ----TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE--EGFPLTEGVFVSYPGPNF 196
                P+ G ND+RFG RF ++++AYD + R       K+  E   L EG +V   GPNF
Sbjct: 141 FCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFTAWKQMGEQRKLQEGTYVMLAGPNF 200

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA----EGLSDVKLSHA 252
           ET AE R+++++G D VGMS VPEVI ARHC L+V   S ITN      E L   K +H 
Sbjct: 201 ETVAESRLLKMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYENLE--KANHM 258

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           + L A + + Q     +   +  I
Sbjct: 259 EVLDAGKAAAQTLERFVSILMESI 282


>UniRef50_UPI0000522022 PREDICTED: similar to nucleoside phosphorylase n=1 Tax=Ciona
           intestinalis RepID=UPI0000522022
          Length = 287

 Score =  200 bits (509), Expect = 4e-50,   Method: Compositional matrix adjust.
 Identities = 106/268 (39%), Positives = 158/268 (58%), Gaps = 7/268 (2%)

Query: 15  DIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL 74
           D +K+   +  P++  I GSGL  L + +EN + + Y ++P F  STV GH G+LV G +
Sbjct: 19  DFLKSKMGNVKPKIGIICGSGLSGLGEVVENKIVVKYSEIPSFVESTVPGHKGQLVFGQI 78

Query: 75  QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALK 134
            G  VVCM+GR H YEG    ++   +R  KL+G E++  TNAAG + PE   G  + +K
Sbjct: 79  SGKDVVCMQGRFHPYEGYPGWVVGFPLRVMKLIGIEMVLATNAAGGINPEFKVGDFMLIK 138

Query: 135 DHIN--TMPG-TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFV 189
           DHI+   + G TP+VG ND  FG RF  + +AYD   R L ++ A + G+   + +GV+ 
Sbjct: 139 DHISFTGLAGYTPLVGPNDSSFGPRFPPMNDAYDKNLRTLFKQCASDLGYDDFMRDGVYC 198

Query: 190 SYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN--MAEGLSDV 247
           +  GP++ET AE+R++  +GGD  GMS V EV++ARHC +KV+A S ITN  + E  +D 
Sbjct: 199 NVFGPSYETIAELRLLLKLGGDAAGMSTVQEVVTARHCGIKVIACSLITNECILEYDTDK 258

Query: 248 KLSHAQTLAAAELSKQNFINLICGFLRK 275
            + H + L  A         L+  F+ K
Sbjct: 259 TVCHDEVLQTANDRAHQMQTLVAKFIGK 286


>UniRef50_C3ZRV1 Putative uncharacterized protein (Fragment) n=1 Tax=Branchiostoma
           floridae RepID=C3ZRV1_BRAFL
          Length = 286

 Score =  199 bits (506), Expect = 8e-50,   Method: Compositional matrix adjust.
 Identities = 109/268 (40%), Positives = 157/268 (58%), Gaps = 10/268 (3%)

Query: 16  IIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQ 75
           ++KT K  + P+VA I GSGLG LAD ++    I Y  +P FP STV GH G LV GHL 
Sbjct: 12  LLKTTK--YRPKVAVICGSGLGGLADVVQQQDVIDYRDIPNFPQSTVQGHRGRLVFGHLA 69

Query: 76  GVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKD 135
           G  V+CM+GR H Y+G  +  +   +R FK++G E LF TNAAG L      G ++ +KD
Sbjct: 70  GKSVICMQGRFHQYQGYPLWKVAMPVRVFKMIGVETLFVTNAAGGLNRNYNIGDIMIVKD 129

Query: 136 HINTMPG----TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF--PLTEGVFV 189
           HI +MPG     P+ G  D+RFG+    +   YD   R L ++VA + G    + EGV V
Sbjct: 130 HI-SMPGMTTDNPLKGFYDERFGKPSSPVTELYDRGLRELARRVAGDLGLGEAVREGVLV 188

Query: 190 SYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDV-K 248
              GP+F+T +   M++ +G D VGMS  PEV  ARHC ++V+ +S +T+MA   SD+  
Sbjct: 189 QVGGPSFDTVSVFNMLRRLGADCVGMSSAPEVTVARHCGIRVLGLSLVTDMAPMESDLPP 248

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKI 276
            +H + L  A+    +  NL+C  + ++
Sbjct: 249 TNHQEILQTAKTRAVDVQNLVCEMISQL 276


>UniRef50_C4QLI3 Purine nucleoside phosphorylase n=2 Tax=Schistosoma mansoni
           RepID=C4QLI3_SCHMA
          Length = 414

 Score =  198 bits (504), Expect = 1e-49,   Method: Compositional matrix adjust.
 Identities = 114/258 (44%), Positives = 157/258 (60%), Gaps = 13/258 (5%)

Query: 24  FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
             P +  I GSGLG LAD +++ + I Y K+P FP ++V GH+G L+ G L G  VV M+
Sbjct: 152 IVPEIGIICGSGLGKLADGVKDKITIPYTKIPNFPQTSVVGHSGNLIFGTLSGRKVVVMQ 211

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG- 142
           GR H YEG     +   IR  KLLG ++L  +NAAG L   +  G  V LKDHI  +PG 
Sbjct: 212 GRFHMYEGYSNDTVALPIRVMKLLGVKILMVSNAAGGLNRSLKLGDFVILKDHI-YLPGL 270

Query: 143 ---TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNFE 197
                +VG N + FG RF +L+NAYD + R L  +VA+E GF   + +GV+V   GP +E
Sbjct: 271 GLNNILVGPNQEEFGTRFPALSNAYDRDLRKLAVQVAEENGFGNLVHQGVYVMNGGPCYE 330

Query: 198 TAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA--EGLSDVKLSHAQTL 255
           T AE  M+  +G DVVGMS +PEV+ ARHC ++V AVS +TN++  +  SD+K +H + L
Sbjct: 331 TPAECTMLLNMGCDVVGMSTIPEVVIARHCGIQVFAVSLVTNISVLDVESDLKPNHEEVL 390

Query: 256 AA----AELSKQNFINLI 269
           A     AEL +  F  +I
Sbjct: 391 ATGAQRAELMQSWFEKII 408



 Score = 96.3 bits (238), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 46/98 (46%), Positives = 61/98 (62%)

Query: 24  FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
           F P +  I GSGLG LAD +++ + I Y K+P FP ++V GH+G L+ G L G  VV M+
Sbjct: 17  FKPEIGIICGSGLGKLADGVKDKITIPYTKIPNFPQTSVVGHSGNLIFGTLSGRKVVVMQ 76

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSL 121
           GR H YEG     +   IR  KLLG ++L  +NAAG L
Sbjct: 77  GRFHMYEGYSNDTVALPIRVMKLLGVKILMVSNAAGGL 114


>UniRef50_Q9BMI9 Purine-nucleoside phosphorylase n=1 Tax=Schistosoma mansoni
           RepID=Q9BMI9_SCHMA
          Length = 287

 Score =  198 bits (503), Expect = 2e-49,   Method: Compositional matrix adjust.
 Identities = 114/258 (44%), Positives = 157/258 (60%), Gaps = 13/258 (5%)

Query: 24  FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
             P +  I GSGLG LAD +++ + I Y K+P FP ++V GH+G L+ G L G  VV M+
Sbjct: 25  IVPEIGIICGSGLGKLADGVKDKITIPYTKIPNFPQTSVVGHSGNLIFGTLSGRKVVVMQ 84

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG- 142
           GR H YEG     +   IR  KLLG ++L  +NAAG L   +  G  V LKDHI  +PG 
Sbjct: 85  GRFHMYEGYSNDTVALPIRVMKLLGVKILMVSNAAGGLNRSLKLGDFVILKDHI-YLPGL 143

Query: 143 ---TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNFE 197
                +VG N + FG RF +L+NAYD + R L  +VA+E GF   + +GV+V   GP +E
Sbjct: 144 GLNNILVGPNQEAFGTRFPALSNAYDRDLRKLAVQVAEENGFGNLVHQGVYVMNGGPCYE 203

Query: 198 TAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA--EGLSDVKLSHAQTL 255
           T AE  M+  +G DVVGMS +PEV+ ARHC ++V AVS +TN++  +  SD+K +H + L
Sbjct: 204 TPAECTMLLNMGCDVVGMSTIPEVVIARHCGIQVFAVSLVTNISVLDVESDLKPNHEEVL 263

Query: 256 AA----AELSKQNFINLI 269
           A     AEL +  F  +I
Sbjct: 264 ATGAQRAELMQSWFEKII 281


>UniRef50_D2QX64 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2QX64_9PLAN
          Length = 303

 Score =  198 bits (503), Expect = 2e-49,   Method: Compositional matrix adjust.
 Identities = 103/249 (41%), Positives = 144/249 (57%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           TP    ILG+GLG+L DQIE   AI YE +P FP ST   H G LV G L  +PV+ M+G
Sbjct: 49  TPHAGIILGTGLGSLVDQIEVEAAIDYENIPHFPKSTAISHRGRLVCGKLGKLPVMAMEG 108

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H YEG  +  +T  +R  K +G  LL  +NA G + P+   G ++ ++DHIN M   P
Sbjct: 109 RFHMYEGYPLDQVTLPVRVMKAMGANLLVVSNACGGMNPQYRTGDIMLIEDHINLMGANP 168

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           ++G+NDDR G RF  + + Y+        ++A++E      GVFV+  GPN ET AE R 
Sbjct: 169 LIGINDDRLGPRFPDMCHPYEPALIDRALEIARKENIVAHRGVFVAVSGPNLETRAEYRF 228

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           +++IG DVVGMS VPEVI A H +++VV  S IT+M    +       + +A A  ++  
Sbjct: 229 LRLIGADVVGMSTVPEVIVAVHSNMRVVGFSIITDMCLPDALEPADVQKIIAVANTAQPK 288

Query: 265 FINLICGFL 273
              L+ G L
Sbjct: 289 LCKLVQGVL 297


>UniRef50_B0VG85 Purine nucleoside phosphorylase 1 (Purine nucleoside phosphorylase
           I) (PNP I) (PU-NPase I) (Inosine phosphorylase) n=1
           Tax=Candidatus Cloacamonas acidaminovorans
           RepID=B0VG85_9BACT
          Length = 277

 Score =  198 bits (503), Expect = 2e-49,   Method: Compositional matrix adjust.
 Identities = 104/261 (39%), Positives = 153/261 (58%), Gaps = 1/261 (0%)

Query: 17  IKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQG 76
           +KT  P   P++A ILG+GL  +A+      +I Y ++PGF  ST   H G L+L  ++G
Sbjct: 11  LKTKLPK-QPQIAVILGTGLSNMAEVFPLLYSIPYNQIPGFVQSTAPTHKGNLLLCEVEG 69

Query: 77  VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDH 136
           +PV+ ++GR H+YEG  M  +   +R    LG ++L  TNA+GSLR E+  G++V L+DH
Sbjct: 70  IPVIFLQGRFHYYEGYSMQEVVFPVRVLSALGIKVLIVTNASGSLRKELEPGTIVQLQDH 129

Query: 137 INTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNF 196
           IN M   P++G+NDD  GERF S+   YD E   L  KVA + G    +GV+++  GP+ 
Sbjct: 130 INFMGTNPLIGMNDDDLGERFPSMNKVYDPELCLLADKVAFDLGIKTAKGVYIAVTGPSL 189

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLA 256
           ET AE       G D+VGMS VPEVI+ARH  LKV+A S +TN +    ++  S  +   
Sbjct: 190 ETKAECSAFASWGADLVGMSTVPEVITARHSGLKVLAYSIVTNYSNLFHNLAHSQEEIQR 249

Query: 257 AAELSKQNFINLICGFLRKIA 277
            A +S +    LI   + ++ 
Sbjct: 250 IANISGKQLQKLIAELILRLT 270


>UniRef50_D1B5G3 Inosine guanosine and xanthosine phosphorylase family n=2
           Tax=Synergistaceae RepID=D1B5G3_THEAS
          Length = 276

 Score =  197 bits (502), Expect = 2e-49,   Method: Compositional matrix adjust.
 Identities = 99/253 (39%), Positives = 150/253 (59%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           TP +  +LGSG+G     ++N V++ YE++P +P ST  GHAG L +G L  + V  ++G
Sbjct: 21  TPDLVMVLGSGVGDFVRVLDNPVSVPYEEIPWWPRSTAPGHAGVLHVGRLGTINVAVLQG 80

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H+YEG  M  +   +R     G ++   TNA+G +      G  V ++DHIN M   P
Sbjct: 81  RVHYYEGYSMEEVVFPVRVMGEWGAKVFVATNASGGIDRSYSPGQWVLIEDHINLMGANP 140

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           +VG N+D +G RF  +  AYD +   L+++ A   G  L  GV+V+  GP+FET AEIRM
Sbjct: 141 LVGPNEDFWGVRFPDMTEAYDRDLMRLMERAASRIGVALGRGVYVAMSGPSFETPAEIRM 200

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           +  +GG +VGMS VPEVI+ARH  L+V+A+S + N A G+S   L+H + L     +  +
Sbjct: 201 LSKLGGTLVGMSTVPEVIAARHMGLRVLALSCVANYAAGISPNPLTHEEVLREVSRATGD 260

Query: 265 FINLICGFLRKIA 277
              L+  FL +++
Sbjct: 261 LCRLLPAFLEEMS 273


>UniRef50_Q6MGR6 Pnp protein n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MGR6_BDEBA
          Length = 280

 Score =  196 bits (499), Expect = 6e-49,   Method: Compositional matrix adjust.
 Identities = 96/256 (37%), Positives = 144/256 (56%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           K    P++  +LGSGLGA   ++E    I Y+ +P F   TV GH+G L+ G + G  + 
Sbjct: 25  KTSAKPKIGVVLGSGLGAFVKEVEVETTIPYKDIPHFSPPTVEGHSGNLIFGKINGQSIA 84

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
            ++GR H+YEG  M  +    RT  +LG E L  TN+AG     + AG  + ++DHIN M
Sbjct: 85  ILQGRNHYYEGHSMESVVFPTRTLAMLGVETLILTNSAGGFGENMQAGDFMVIEDHINLM 144

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAA 200
              P++G N    G RF  +  AYD     +++ V  ++G    +GV+    GP +ET +
Sbjct: 145 GTNPLMGPNIKELGPRFPDMTEAYDKRLIQIMEDVLMKQGTRYHKGVYCGVSGPTYETPS 204

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAEL 260
           E+R +++IGG  VGMS VPE I+A H  L+V A+S ITN+A G+S  KLSH +    A+ 
Sbjct: 205 EVRYLKLIGGKAVGMSTVPETIAANHLGLRVAALSCITNLAAGISSQKLSHNEVTETAKQ 264

Query: 261 SKQNFINLICGFLRKI 276
            +  F + +  F+  I
Sbjct: 265 VEMQFSSFLREFIAHI 280


>UniRef50_C3J8Q8 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=2 Tax=Bacteria RepID=C3J8Q8_9PORP
          Length = 274

 Score =  196 bits (497), Expect = 1e-48,   Method: Compositional matrix adjust.
 Identities = 105/252 (41%), Positives = 146/252 (57%), Gaps = 6/252 (2%)

Query: 24  FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
           F  ++  ILGSGLG L ++IE+   I Y ++P F  ST  GH G  + G L GVPVV M+
Sbjct: 19  FKAKIGIILGSGLGELGNKIEDPTIIPYSEIPNFAHSTAIGHKGNFICGKLGGVPVVAMQ 78

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           GR H+YEG  M  +T  +R  KL+G E LF +NAAG +      G L+ ++DHIN +P  
Sbjct: 79  GRFHYYEGYPMERVTFPVRVMKLIGVETLFVSNAAGGINNTYHVGDLMIIRDHINNLP-N 137

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIR 203
           P++G N   FG RF  +  AYD +  A  +++AKEE   + +GV+V   GP++ET AE  
Sbjct: 138 PLIGPNMGEFGVRFPDMTRAYDRDLIARAERIAKEENIEVRKGVYVGLTGPSYETPAEYL 197

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL-----AAA 258
             Q +GGD +GMS VPEV+ ARH  ++V  +S ITN          + AQ +     AA+
Sbjct: 198 FYQRVGGDAIGMSTVPEVLVARHAGIRVFGMSVITNEGWHFEGDYTNDAQEVIDAANAAS 257

Query: 259 ELSKQNFINLIC 270
           E   + F  LI 
Sbjct: 258 ERMGRIFQRLIS 269


>UniRef50_B9WDS7 Purine nucleoside phosphorylase, putative n=14 Tax=cellular
           organisms RepID=B9WDS7_CANDC
          Length = 307

 Score =  194 bits (493), Expect = 3e-48,   Method: Compositional matrix adjust.
 Identities = 121/289 (41%), Positives = 161/289 (55%), Gaps = 25/289 (8%)

Query: 5   QFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALAD--QIENAVAISYEKLPGFPVSTV 62
           Q +H      + I  ++    PRV  I GSGLG +AD  Q E  + I Y K+PGF VSTV
Sbjct: 13  QLNHASDTIKNKIDQFQELAQPRVMIICGSGLGGIADVLQAEPKLEIPYSKIPGFKVSTV 72

Query: 63  HGHAGELVLGHL--QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
            GHAG+LV G +    VPV+CM GR HFYEG      T  +R  KLLG   +  TNAAG 
Sbjct: 73  PGHAGKLVFGLIGKSKVPVMCMVGRLHFYEGYSFQETTFPVRVAKLLGISSVVVTNAAGG 132

Query: 121 LRPEVGAGSLVALKDHINTMPGT----PMVGLNDDRFGERFFSLANAYDAEYRALLQKVA 176
           + P+   G L+ ++DHIN  PG     P+ G N   FG RF  L++AYD E R L    A
Sbjct: 133 VNPKFKPGDLMVIEDHIN-FPGLAGYHPLRGPNLSEFGPRFQPLSDAYDYELRKLFITTA 191

Query: 177 KEE---GFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVA 233
           +++      + EG +    GP FE+ AE+RM++ +GGD VGMS VPEVI ARH  L+V+A
Sbjct: 192 RDKLGITRSIYEGTYFFAAGPTFESRAEVRMIKTMGGDAVGMSTVPEVIVARHSGLRVLA 251

Query: 234 VSAITNMAEG-------------LSDVKLSHAQTLAAAELSKQNFINLI 269
           +S ITN   G             L +   SHA+ L AA+ + ++   +I
Sbjct: 252 LSLITNAGVGDKPPSAFDENPPALDEGMASHAEVLEAADEASKDVQKII 300


>UniRef50_D0MFN5 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Rhodothermus marinus DSM 4252 RepID=D0MFN5_RHOM4
          Length = 279

 Score =  193 bits (490), Expect = 5e-48,   Method: Compositional matrix adjust.
 Identities = 108/250 (43%), Positives = 142/250 (56%), Gaps = 2/250 (0%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P VA ILGSGLGALA+ +  AV +   ++PG+P  TV GHAG LV G L+G  VV ++GR
Sbjct: 22  PEVALILGSGLGALAEAVSEAVEVPVREIPGYPAPTVSGHAGRLVFGRLEGCRVVVLQGR 81

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H YEG     +T  +R    LG + L  TNAAG L P    G+L+ + DHIN     P+
Sbjct: 82  LHCYEGYPPQTVTLPVRLVHALGAQRLIVTNAAGGLNPHFRPGTLMFIVDHINAAFRNPL 141

Query: 146 VGLNDDR--FGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIR 203
           VG   DR         ++ AYD ++ A  + VA   G P   GV++   GP++ET AEIR
Sbjct: 142 VGQLADRRPLMRGAPDMSRAYDLDWLAEAETVALRLGIPTQRGVYLWTLGPSYETKAEIR 201

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
           M + +G D VGMS VPEV+ AR   +KV+ +S ITNMA GL    L+H + L      + 
Sbjct: 202 MYRRMGADAVGMSTVPEVLQARQLGMKVLGISTITNMAAGLHAGPLTHEEVLQVGLQVRD 261

Query: 264 NFINLICGFL 273
               LI G L
Sbjct: 262 RLERLIRGIL 271


>UniRef50_D0LL71 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Haliangium ochraceum DSM 14365
           RepID=D0LL71_HALO1
          Length = 275

 Score =  192 bits (489), Expect = 8e-48,   Method: Compositional matrix adjust.
 Identities = 101/254 (39%), Positives = 143/254 (56%)

Query: 23  DFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM 82
           D  P+V  ILGSGLG+ AD++E+AV++ + ++P    ST  GHAG LV G   GV  + M
Sbjct: 8   DRKPQVGLILGSGLGSFADELEDAVSVPFGEVPHVLPSTAPGHAGRLVCGTRAGVSCIVM 67

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
           +GR H YEG      T  +R    LG   L  TNAAG +  +   G+ + ++DHIN M  
Sbjct: 68  QGRLHLYEGHPAADATFPVRCMIALGARTLLVTNAAGGMHGDWEPGTFMLIRDHINMMHD 127

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEI 202
            P+ G ND+R G RF  +  AYD   R L  + A E G  L +GV+++  GP +ET AE+
Sbjct: 128 HPLRGPNDERLGPRFPDMTRAYDPALRELALRAADEVGVSLQQGVYLASTGPTYETPAEV 187

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
            MM+ +G D  GMS VPEVI ARH   + +  S ITN A G++   L+HA+ +      +
Sbjct: 188 MMMRGLGADACGMSTVPEVIVARHMGARCLGFSCITNKAAGITGQPLNHAEVMETGARVR 247

Query: 263 QNFINLICGFLRKI 276
                L+   L ++
Sbjct: 248 SQLTKLLDAVLAEL 261


>UniRef50_C9LGF9 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Prevotella tannerae ATCC 51259
           RepID=C9LGF9_9BACT
          Length = 291

 Score =  192 bits (489), Expect = 9e-48,   Method: Compositional matrix adjust.
 Identities = 98/251 (39%), Positives = 148/251 (58%), Gaps = 1/251 (0%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P+ A +LG+GLG LA +I+      Y+ +P FPVSTV GH+G L+ GHL G P++ ++GR
Sbjct: 41  PQTAIVLGTGLGKLAQEIDVVDEFPYKDIPNFPVSTVEGHSGRLIFGHLGGKPIMALEGR 100

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H+YEG  M  +T   R    LG + LF +NA+G   P+   G L+ + DHIN  P  P+
Sbjct: 101 FHYYEGYTMQEVTFPERVMYALGIKNLFLSNASGGTNPDFEIGDLMLITDHINFQPEHPL 160

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMM 205
            G N    G RF  ++ AYD  +    + +A+E+G  + EGV+++  GP +ET AE +M 
Sbjct: 161 HGPNIPT-GPRFPDMSEAYDRAFLEAARNIAREKGIKVVEGVYLADQGPTYETPAEYKMY 219

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNF 265
           +++G D VGMS VPEVI ARHC ++   +S IT++      V++SH +   AA   +   
Sbjct: 220 RLLGADAVGMSTVPEVIVARHCGIRCFGISIITDLGVEGKIVEVSHEEVQKAANAVQPLM 279

Query: 266 INLICGFLRKI 276
             +    ++KI
Sbjct: 280 AEIFRELIKKI 290


>UniRef50_C3FBK6 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Bacillus thuringiensis serovar monterrey BGSC
           4AJ1 RepID=C3FBK6_BACTU
          Length = 266

 Score =  192 bits (487), Expect = 1e-47,   Method: Compositional matrix adjust.
 Identities = 98/250 (39%), Positives = 150/250 (60%), Gaps = 3/250 (1%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           + A ++GSGL  + +++E+   I Y ++P F  ST   H GEL+ G+L G PVVC+ GR 
Sbjct: 20  KTAIVIGSGLSGIIEKVEDKNIIPYGEIPEFLHSTAPTHRGELISGYLYGKPVVCLNGRF 79

Query: 87  HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
           H+YEG  M  + + I+  KLLG E +  TNA+GS+  E+  G LV ++DHIN     P+ 
Sbjct: 80  HYYEGYQMQQVAEYIKVLKLLGIEHIILTNASGSMYQEIVPGDLVVVEDHINFSGLNPLR 139

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQ 206
           G ND+ FG RF  ++NAY    + L++KV +     L +G +V   GP+FETAAEIR  +
Sbjct: 140 GKNDESFGPRFVDMSNAYS---KRLIEKVFENSSNGLKKGTYVYGTGPSFETAAEIRAFK 196

Query: 207 IIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFI 266
            +GG +VGMS VPEVI   +C ++V+ +S ++N A G+    +S  + +    L++  F 
Sbjct: 197 TLGGTIVGMSTVPEVIMCAYCGIEVLTISCVSNYAPGIPGSNVSDEELVRVTGLAQDKFS 256

Query: 267 NLICGFLRKI 276
            ++     KI
Sbjct: 257 KVLEELFNKI 266


>UniRef50_A7HJP7 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Fervidobacterium nodosum Rt17-B1
           RepID=A7HJP7_FERNB
          Length = 267

 Score =  191 bits (485), Expect = 3e-47,   Method: Compositional matrix adjust.
 Identities = 98/244 (40%), Positives = 144/244 (59%), Gaps = 4/244 (1%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P++A ILGSGLG L +++E    ++Y+ +P FP ST  GH G+LV G L G  VV + GR
Sbjct: 20  PKIALILGSGLGFLTEKVEFKQELNYKDIPNFPYSTAPGHEGKLVFGELFGKEVVVLSGR 79

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H YEG   + +   I T K+LG E +  TNAAG++      G +V +KD IN     P+
Sbjct: 80  FHIYEGWNPSDIKIVIHTLKMLGIEKILITNAAGAVNTTYKPGDIVLVKDVINFTFRNPL 139

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMM 205
            G ND+  G RF  +   +D ++   L+++  E    + EGV++S  GP +ET AEIR +
Sbjct: 140 RGPNDNDLGPRFPDMLGVFDKDWMGKLKQIYPE----MKEGVYISLTGPTYETPAEIRAV 195

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNF 265
           + +G D+VGMS VPE+I   H  +K + +S  TNMA G+ D  LSH + +  A L K+ F
Sbjct: 196 RKMGADLVGMSTVPELIVCAHVGIKALVLSCATNMAAGILDQPLSHEEVVEVANLVKEKF 255

Query: 266 INLI 269
             ++
Sbjct: 256 TEIV 259


>UniRef50_A8PXS8 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           family protein n=4 Tax=root RepID=A8PXS8_BRUMA
          Length = 295

 Score =  190 bits (483), Expect = 4e-47,   Method: Compositional matrix adjust.
 Identities = 108/268 (40%), Positives = 155/268 (57%), Gaps = 12/268 (4%)

Query: 16  IIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQ 75
           I+K  +    P++  I GSGLG++AD IE A  +SY K+PGFP+S V GH   LV G++ 
Sbjct: 29  ILKQIQLKEVPKIGIICGSGLGSIADFIEQAEILSYTKIPGFPISHVIGHKSNLVFGYIN 88

Query: 76  GVPVVCMKGRGHFYE-GRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALK 134
              V+CM+GR H YE G  + +    +R   LLG E L  +NAAG L      G L+ +K
Sbjct: 89  EKYVICMQGRFHPYEYGMDLALCAMPVRILHLLGVETLIVSNAAGGLNSNFKVGDLMIIK 148

Query: 135 DHINTMPG----TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVS 190
           DHI   PG    +P VGL+D RFGERF SL  AYD + R L   VA+ +   + EGV+  
Sbjct: 149 DHI-FFPGLAGFSPFVGLHDQRFGERFVSLHEAYDPKLRKLAIDVARRQKIRIHEGVYAM 207

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA--EGLSDVK 248
             GP FE+ AE+RM++++G D +GMS   EV+ A    ++V   S ITN+A  +  + V 
Sbjct: 208 NGGPQFESPAELRMLKMLGTDAIGMSTCHEVVVACQMGMRVFGCSLITNIANLDHENAVM 267

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKI 276
           ++H + L   E +++      C F+ +I
Sbjct: 268 VTHEEVLKTGEEAQER----TCSFVSEI 291


>UniRef50_Q5YBA4 Purine nucleoside phosphorylase n=2 Tax=Singapore grouper
           iridovirus RepID=Q5YBA4_9VIRU
          Length = 285

 Score =  190 bits (483), Expect = 4e-47,   Method: Compositional matrix adjust.
 Identities = 101/259 (38%), Positives = 148/259 (57%), Gaps = 9/259 (3%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P +  + GSGLG + D +E ++ ++Y  +P FPV +V GHAG L+ G + GV  VCMKGR
Sbjct: 22  PVLGIVCGSGLGKIGDSLETSITVAYSDIPNFPVGSVKGHAGSLIFGSVNGVSCVCMKGR 81

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG--- 142
            H YEG      T  +R FK LG +++  TNAAG L P    G  + ++DHIN +PG   
Sbjct: 82  FHLYEGHTAARATFPMRVFKALGVKIVVLTNAAGGLNPSYRPGDFMVVRDHIN-LPGLAG 140

Query: 143 -TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG--FPLTEGVFVSYPGPNFETA 199
             P+ G NDD  GERF S+ + YD   R      A+E G  +   EGV+    GP+FET 
Sbjct: 141 ANPLTGPNDDTEGERFPSMTSVYDKTLRKYAISAARELGMSYATHEGVYCCVNGPSFETP 200

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM--AEGLSDVKLSHAQTLAA 257
           AE ++++++G D VGMS  PE I A+H  ++ +AVS I+N+  +   +  + +H + L A
Sbjct: 201 AECKILRLMGSDAVGMSTAPETIVAKHGGMRCLAVSLISNVIASNCETPAEPTHEEVLRA 260

Query: 258 AELSKQNFINLICGFLRKI 276
            E +      L+   + KI
Sbjct: 261 GEEASARMTALVKLVIEKI 279


>UniRef50_B6YR86 Purine-nucleoside phosphorylase n=1 Tax=Candidatus Azobacteroides
           pseudotrichonymphae genomovar. CFP2 RepID=B6YR86_AZOPC
          Length = 270

 Score =  190 bits (482), Expect = 5e-47,   Method: Compositional matrix adjust.
 Identities = 96/232 (41%), Positives = 134/232 (57%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  ILG+GLG LA+ I N   I YEK+P FP+STV GH G+L++G L    V  M+GR 
Sbjct: 21  KIGIILGTGLGELANSITNKTEIPYEKIPHFPISTVEGHNGKLLIGQLGEKSVAVMQGRF 80

Query: 87  HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
           H+YEG  M+ +T  +R  + L    L  +NAAG +      G ++ ++DHIN  P  P+ 
Sbjct: 81  HYYEGYDMSHITYPVRVMQFLEFNYLIISNAAGGINATFQIGDIMLIEDHINLFPKNPLR 140

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQ 206
           G N   FG RF  ++  YD E R+L   V K+    L  G +V   GP FET AE    +
Sbjct: 141 GRNFPEFGVRFPDMSQVYDKELRSLAISVTKKNNIKLQFGTYVGVQGPTFETPAEYNYFR 200

Query: 207 IIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
           IIGGD +GMS +PEVI ARH  L+V+A S IT++      ++++H     A 
Sbjct: 201 IIGGDAIGMSTIPEVIVARHGGLRVLAFSIITDLGILGKIIEVNHKDVRKAG 252


>UniRef50_D1Y3S3 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y3S3_9BACT
          Length = 279

 Score =  190 bits (482), Expect = 5e-47,   Method: Compositional matrix adjust.
 Identities = 104/248 (41%), Positives = 140/248 (56%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           PR A ILGSGLG LA+ +E+ V I Y ++P +  ST  GHAG LV G L GVPVV M+GR
Sbjct: 25  PRAALILGSGLGMLAEAVEDPVVIPYAEIPHWKTSTAPGHAGRLVCGTLSGVPVVVMQGR 84

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H YEG      T  IR F   G + L  TNA+G +  E   G +  + DHIN     P+
Sbjct: 85  LHCYEGYTPQETTFPIRVFGQWGVKTLLVTNASGGINYEYANGDVALITDHINLTGMNPL 144

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMM 205
            G N+  +G RF  ++  Y     ALL++ A+  G     GV++   GP++ET AEIRM 
Sbjct: 145 RGANNPEWGARFPDMSEPYSRRLVALLEESAQSLGLLTRRGVYIGLAGPSYETPAEIRMA 204

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNF 265
           + +G D+VGMS V EVI A H  ++V  VS + N+A G+  VKLS  + L+    +    
Sbjct: 205 RAMGADLVGMSTVHEVIVANHMGMEVCGVSCVANLAAGMRPVKLSEEEVLSEMGRAAARI 264

Query: 266 INLICGFL 273
             L+  FL
Sbjct: 265 SALVGKFL 272


>UniRef50_B2KC58 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Elusimicrobium minutum Pei191 RepID=B2KC58_ELUMP
          Length = 273

 Score =  190 bits (482), Expect = 6e-47,   Method: Compositional matrix adjust.
 Identities = 96/247 (38%), Positives = 144/247 (58%)

Query: 23  DFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM 82
           +F P +A I GSGL     +++N   I Y+ +P F  STV GH+G L+ G  +G  ++ M
Sbjct: 20  NFKPEIALITGSGLAGSVPELKNKTVIPYKNIPDFLNSTVSGHSGNLIFGTYKGKKLMVM 79

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
           +GR H+YEG  +  +  A R   +LG + L  + A GS+  ++  GSL  L DHIN M  
Sbjct: 80  QGRFHYYEGHCIKDIALAPRVMGMLGVKTLMVSAAVGSINAKLTPGSLAVLSDHINLMAT 139

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEI 202
            P++G  D  FG+ F  L+ AYD +   L+   AK+        V+++  GPNFET +EI
Sbjct: 140 NPLIGNYDPAFGQMFVDLSEAYDKKLVKLISSKAKKLKINNAPAVYIAVTGPNFETPSEI 199

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
           +  + +G DVVGMSVV EVI++R   +KV   + +TN+A G+S   LSHA+TL+  +  +
Sbjct: 200 KAFRTLGADVVGMSVVHEVIASRQAGIKVCGCAWVTNLASGISKTPLSHAETLSETKKIE 259

Query: 263 QNFINLI 269
             F  L+
Sbjct: 260 GKFKTLL 266


>UniRef50_A9G8Q6 DeoD protein n=8 Tax=Bacteria RepID=A9G8Q6_SORC5
          Length = 283

 Score =  189 bits (480), Expect = 1e-46,   Method: Compositional matrix adjust.
 Identities = 99/251 (39%), Positives = 143/251 (56%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           PRV  +LGSGLG   D++   V + Y  +PG P   V GH G L  G +  V V C++GR
Sbjct: 22  PRVGVVLGSGLGGWGDELAELVKVPYADIPGMPRPAVAGHPGFLCAGRVGDVQVACLQGR 81

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H YEG  +  +   +R    LGC  +  TNAAG + P   AG L+ L DH+N M   P+
Sbjct: 82  AHVYEGHPLAKVVFGVRVLARLGCRAVLLTNAAGGINPGFAAGDLMLLTDHLNLMGANPL 141

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMM 205
           VG ND+  G+RF  +  A+D     L +  A + G  L EGV+ +  GP +ET AEIRM+
Sbjct: 142 VGPNDEALGKRFPDMTYAHDPRLLELAKTAASDAGVALREGVYAALLGPTYETPAEIRML 201

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNF 265
           + +G D VGMS VPE+I+ RH  +   A+S +TN+A GL+  +L H +    A  ++  F
Sbjct: 202 RTLGADAVGMSTVPEIIALRHMGVPAAAISCVTNLAAGLTKRELDHKEVEETAREARARF 261

Query: 266 INLICGFLRKI 276
             L+  ++R++
Sbjct: 262 TALLSAWVRRV 272


>UniRef50_C7MNU9 Inosine guanosine and xanthosine phosphorylase family protein n=2
           Tax=Coriobacteriaceae RepID=C7MNU9_CRYCD
          Length = 284

 Score =  188 bits (478), Expect = 1e-46,   Method: Compositional matrix adjust.
 Identities = 106/259 (40%), Positives = 141/259 (54%), Gaps = 6/259 (2%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           +P++  +LGSGL  LAD+I +AV I + ++P     T  GH G  V G L G  V+ M+G
Sbjct: 26  SPQIGLVLGSGLNPLADKIADAVHIDFTEVPHMKTVTAAGHVGRFVCGELGGQTVLAMQG 85

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H YEG     +   I     LG E +  TNAAG+L      G   A+ DHIN     P
Sbjct: 86  RLHAYEGYTAQDVAFPIWLMHRLGIETVITTNAAGALNKSFAPGDFCAISDHINFTGRNP 145

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           +VG++     ER FS+  AYDA  RA    VA E+   L EGV++   GP+FET AEIRM
Sbjct: 146 IVGIDPSELAERCFSMTAAYDATLRATAHTVASEKSITLHEGVYLGVLGPSFETPAEIRM 205

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQT------LAAA 258
            +  G D V MSVV EVI+ARH  ++V+ +S ITN A GL +     A        LA A
Sbjct: 206 FRSWGADTVAMSVVEEVIAARHVGMRVLGLSLITNCAAGLGETDTCDANAANGEAVLATA 265

Query: 259 ELSKQNFINLICGFLRKIA 277
              + +F  L+ G L K++
Sbjct: 266 SAYQDDFAALVIGILEKLS 284


>UniRef50_A3ZZ29 Purine nucleoside phosphorylase n=1 Tax=Blastopirellula marina DSM
           3645 RepID=A3ZZ29_9PLAN
          Length = 267

 Score =  188 bits (478), Expect = 2e-46,   Method: Compositional matrix adjust.
 Identities = 98/219 (44%), Positives = 142/219 (64%), Gaps = 7/219 (3%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P+   ILG+GLG+L + I+   +I Y+ LP FP +T   HAG L+ G L GV V+ M+GR
Sbjct: 16  PKAGVILGTGLGSLTEGIDVEASIDYDDLPYFPQTTALSHAGRLIGGKLAGVDVLVMEGR 75

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H YEG  +  +T  +R  K LG ELL  +NA+G + P   +G ++ ++DHIN M  +P+
Sbjct: 76  FHLYEGYSLDQITLPVRVMKALGAELLVVSNASGGMNPYYESGDIMLIEDHINLMWRSPL 135

Query: 146 VGLNDD-RFGERFFSLANAYDAEYRALLQK---VAKEEGFPLTEGVFVSYPGPNFETAAE 201
            G  D+ +  ERF  +++ YD   R LLQ+   +A+ E   + +GV+V+  GPN+ET AE
Sbjct: 136 QGHADEAKQAERFPDMSSPYD---RRLLQRAAEIARREEIRVHQGVYVAMSGPNYETRAE 192

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
            R ++ IGGDVVGMS VPEVI AR C L+V+A+S +TN+
Sbjct: 193 YRFLRNIGGDVVGMSTVPEVIVARQCGLQVLALSTVTNV 231


>UniRef50_C5EQ75 Purine nucleoside phosphorylase I n=1 Tax=Clostridiales bacterium
           1_7_47FAA RepID=C5EQ75_9FIRM
          Length = 270

 Score =  187 bits (476), Expect = 3e-46,   Method: Compositional matrix adjust.
 Identities = 96/256 (37%), Positives = 147/256 (57%), Gaps = 1/256 (0%)

Query: 14  IDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH 73
           +D I++ +    P +A ILGSGLG  A Q+ENA  I YE +P FP  TV GH+G L +G 
Sbjct: 9   VDYIRS-RTRKVPEIAMILGSGLGDYASQLENADIIPYEDIPNFPKPTVSGHSGRLFVGE 67

Query: 74  LQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVAL 133
           + G  +  M+GR H+YEG     +T  +R  ++LG   L  TNA G++      G L+ +
Sbjct: 68  IAGKCIAVMQGRNHYYEGYDTQTITYPVRVLRMLGAGSLILTNACGAVSRHFVPGDLMII 127

Query: 134 KDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPG 193
           ++H+      P+ G + +  G RF  ++  YD EY  L ++ AK+ G  + +GV+  +PG
Sbjct: 128 ENHLAHFCPPPLRGAHLEELGPRFTDMSRPYDPEYMELARRCAKDMGIRIQQGVYGYWPG 187

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQ 253
           P +ETAAE+R   ++G DVVGMS V E + A +C ++V+ +S ITNM    S  K SH +
Sbjct: 188 PTYETAAEVRAYGVLGADVVGMSTVAEDMVAVNCGMRVLGISCITNMTCIHSSGKTSHDE 247

Query: 254 TLAAAELSKQNFINLI 269
            +   E   +  + L+
Sbjct: 248 VIQVMEQISEKTVKLL 263


>UniRef50_C8V0B3 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           (AFU_orthologue; AFUA_6G05320) n=17 Tax=Leotiomyceta
           RepID=C8V0B3_EMENI
          Length = 315

 Score =  187 bits (475), Expect = 4e-46,   Method: Compositional matrix adjust.
 Identities = 118/297 (39%), Positives = 165/297 (55%), Gaps = 35/297 (11%)

Query: 15  DIIKTYKPD--FTPRVAFILGSGLGALADQIEN--AVAISYEKLPGFPVSTVHGHAGELV 70
           D IK   P+    PRVA + GSGLG LA+ I+N   V I Y  +P FP  TV GHAG+LV
Sbjct: 18  DFIKKLLPEPLKAPRVAIVCGSGLGGLANTIDNDLRVEIDYSDIPHFPHLTVAGHAGKLV 77

Query: 71  LGHL-QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGS 129
            G + + VPVV M GR H+YEG  +  +T  IR FKLLG + +  TNAAG L P+   G 
Sbjct: 78  FGLIDKKVPVVLMVGRAHYYEGHSIDQVTFPIRVFKLLGIDTVVLTNAAGGLNPDYAVGD 137

Query: 130 LVALKDHI--NTMPGT-PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP---- 182
           +V L DHI    + G  P+ G N + FG RF  L++AYD + R  + +  ++   P    
Sbjct: 138 IVLLNDHIFLAGLAGIHPLRGPNCEEFGPRFPPLSDAYDLDLRRQVHEAWRKYLDPCSKR 197

Query: 183 -LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA 241
            L EGV+    GP++ET AE R+++ +G D+VGMS VPE++ ARHC L+++A S +TN A
Sbjct: 198 RLHEGVYAFVCGPSYETRAECRLLRQLGADLVGMSTVPEIVVARHCGLRIIAFSLVTNNA 257

Query: 242 -------------EG---------LSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
                        +G         L + K +H + L A   + Q+   L+   + KI
Sbjct: 258 VLSPVPRGDDHLIQGRDVKELDAILQEGKANHEEVLEAGREAAQDMQKLVVHVISKI 314


>UniRef50_C0BWU4 Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM
           15053 RepID=C0BWU4_9CLOT
          Length = 276

 Score =  187 bits (474), Expect = 4e-46,   Method: Compositional matrix adjust.
 Identities = 100/229 (43%), Positives = 133/229 (58%), Gaps = 3/229 (1%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P V  +LG+ LG +  +I +   I Y+++P F +ST  GHAG+LV G L G  V+CM GR
Sbjct: 25  PAVGIVLGTCLGEIEHEITDKTEIYYKEIPNFLISTAPGHAGKLVCGRLGGKRVLCMAGR 84

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H YEG     +   +  FKLLG   L  TNAAG++      G +  +KDHIN    +P 
Sbjct: 85  FHHYEGYSFEELRIPVYVFKLLGIRTLILTNAAGAVNLNYETGDICVIKDHINLCGVSPQ 144

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMM 205
            G N    GERFFS+ + Y    R L +  A E GF L EGV+   PGP FET AEIR M
Sbjct: 145 RGENIPELGERFFSMNDVYTPSLRRLAKDAAVELGFSLQEGVYYFAPGPQFETPAEIRAM 204

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQT 254
           +++G D+VGMS VPE I+A HC + V+ +S  TN++   +D  L H  T
Sbjct: 205 RLLGADMVGMSTVPEAITAAHCRMDVLGLSLATNLS---ADRVLDHDVT 250


>UniRef50_B9XJR6 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=bacterium Ellin514 RepID=B9XJR6_9BACT
          Length = 274

 Score =  186 bits (471), Expect = 9e-46,   Method: Compositional matrix adjust.
 Identities = 108/269 (40%), Positives = 140/269 (52%), Gaps = 2/269 (0%)

Query: 9   NPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGE 68
           NPL     +        P +A +LGSG      ++   + ISYEKL GFP   V GHAG+
Sbjct: 6   NPLITAQQLGRLS-QLRPTLAIVLGSGFQQAIAEMRIELEISYEKLKGFPPVGVSGHAGK 64

Query: 69  LVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAG 128
           L+LG+L   PV+ + GR H+YEG  M  +T A R     G   L  TNAAG +  +  AG
Sbjct: 65  LILGYLGKTPVLVLSGRAHYYEGHEMEQVTYATRVLAEFGIRDLLLTNAAGGVNRKFKAG 124

Query: 129 SLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVF 188
             + L DHIN M   P+ G    +   RF  +   YD +   LL K  K  G  L +GV+
Sbjct: 125 DFMVLTDHINFMGINPLRGPTIAKL-PRFVDMTCTYDQQLSQLLHKAGKLCGLKLQKGVY 183

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK 248
           ++  GP++ET AEIR    +G D VGMS VPE I AR C + V  VS ITN+A G     
Sbjct: 184 LAVSGPSYETPAEIRAFATLGADAVGMSTVPEAIVARQCGINVAGVSCITNLAAGCGGDT 243

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKIA 277
           LSHA+ L  AE  K     L+  F +  A
Sbjct: 244 LSHAEVLETAERVKNMAARLLNSFAKLYA 272


>UniRef50_A7VBG8 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A7VBG8_9CLOT
          Length = 306

 Score =  186 bits (471), Expect = 1e-45,   Method: Compositional matrix adjust.
 Identities = 99/246 (40%), Positives = 145/246 (58%), Gaps = 3/246 (1%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
           T K    P +  +LGSGLG  A  +++ V + Y+++PGFPVSTV GH G  + G+  G P
Sbjct: 46  TDKIKMKPEIGIVLGSGLGD-AFTMDDPVYVYYKEIPGFPVSTVAGHKGRFIFGYSCGKP 104

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           +V M+GR H+YEG  M  +   IR   LLG   L  TNAAG +  E+  G ++ + D I+
Sbjct: 105 IVVMQGRVHYYEGYSMQDVVKPIRLMGLLGIRWLILTNAAGGISEELAPGDIMIISDQIS 164

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFET 198
           +   +P++G N D FG RF  +++ YD E   + +KV ++ G  + EG ++   GP +ET
Sbjct: 165 SFVPSPLIGRNIDEFGVRFPDMSHIYDKEKIQISRKVFEQIGLHVVEGTYIQATGPQYET 224

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL-AA 257
            AEIRM Q++G D VGMS   E I+A H  ++V   SAI+N A GL   +L H   L  +
Sbjct: 225 PAEIRMFQLLGADAVGMSTACEAIAACHMGIRVSGFSAISNKAAGLG-AELKHEDILDRS 283

Query: 258 AELSKQ 263
            E+S +
Sbjct: 284 KEMSDK 289


>UniRef50_B4D4P3 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Chthoniobacter flavus Ellin428 RepID=B4D4P3_9BACT
          Length = 265

 Score =  185 bits (470), Expect = 1e-45,   Method: Compositional matrix adjust.
 Identities = 94/259 (36%), Positives = 143/259 (55%), Gaps = 6/259 (2%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL 71
             ++++     DF P    +LGSGLG+L ++++  +++ YE++ G PVST  GHAG  V 
Sbjct: 8   LSVEVLPKAVRDFQPEWGIVLGSGLGSLVEEVDAILSLPYEEITGMPVSTAPGHAGRFVF 67

Query: 72  GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
           G L G  V+  +GR H YEGR    +T A+R  + +G   L  TNAAG+L P+   GS +
Sbjct: 68  GRLAGCRVMMAQGRVHLYEGRTADEVTAAVRFMENIGVRRLLLTNAAGTLNPKFEPGSWM 127

Query: 132 ALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSY 191
            L DH+N    +P++G  +      F  ++  Y  E R      A EEG  L EGV+   
Sbjct: 128 MLNDHLNLTGTSPLLGAPN------FADMSAVYSPELRVRFATAAGEEGLVLHEGVYAGL 181

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH 251
            GP +ET AE+RM++++G D VGMS V E I AR   +++ A S +TN A GL    LSH
Sbjct: 182 LGPQYETPAEVRMLRMLGADAVGMSTVLEAIQARALKMEIAAFSCLTNWAAGLGTKPLSH 241

Query: 252 AQTLAAAELSKQNFINLIC 270
            + +    ++    + ++ 
Sbjct: 242 EEVIETGRVASAQMLRILT 260


>UniRef50_Q1NL01 Inosine guanosine and xanthosine phosphorylase:Purine nucleoside
           phosphorylase I, inosine and guanosine-specific
           (Fragment) n=3 Tax=Deltaproteobacteria
           RepID=Q1NL01_9DELT
          Length = 288

 Score =  185 bits (469), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 96/249 (38%), Positives = 138/249 (55%), Gaps = 1/249 (0%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P V  +LG+GLG LA  +   V I Y  +P FP +TV GH G LV G L G  V  M+GR
Sbjct: 39  PEVVLVLGTGLGQLATMVAEPVQIPYADIPHFPRATVSGHHGNLVCGRLCGRQVAVMQGR 98

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H+YEG     +T  IR   LLG   L  +NAAG L P+   G+L+ + DH+N +P  P+
Sbjct: 99  FHYYEGYSARELTMPIRVLSLLGARQLLVSNAAGGLNPQFAPGTLMLINDHLNLIPDNPL 158

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP-LTEGVFVSYPGPNFETAAEIRM 204
            G N + +GERF  ++ AYD E R    +  +  G   + EG++ + PGP+ ET AE R 
Sbjct: 159 RGANIEAWGERFPDMSVAYDRELRGRAWQSVRRLGLERVEEGIYAAIPGPSLETPAETRH 218

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           ++  G D VGMS VPEVI ARH  ++V+ V+ ++N+ +  +   +     +  +E   Q 
Sbjct: 219 LRQCGADAVGMSTVPEVIVARHAGMRVLGVAVVSNVNDPDNFQPIRLTDIIRESEACAQR 278

Query: 265 FINLICGFL 273
              L+   L
Sbjct: 279 LQQLLWELL 287


>UniRef50_A9URE9 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9URE9_MONBE
          Length = 311

 Score =  184 bits (467), Expect = 3e-45,   Method: Compositional matrix adjust.
 Identities = 107/267 (40%), Positives = 149/267 (55%), Gaps = 12/267 (4%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           K    P +  I GSGLG LA ++++AV I YE++P FPVSTV GH G+LV G L G PVV
Sbjct: 37  KAKTQPLIGIICGSGLGGLAAEVQDAVTIGYEEIPNFPVSTVAGHEGKLVFGTLGGAPVV 96

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
            MKGR H YEG   + +   IRT   LG + LF TNAAG L      G L+ L+DH+N  
Sbjct: 97  VMKGRLHCYEGYAFSRIAVPIRTLCALGIKYLFVTNAAGGLNESFEVGDLMMLEDHLN-F 155

Query: 141 PG----TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF-----PLTEGVFVSY 191
           PG     P+VG +DDR+G RF  ++  YD + R + ++            P   GV+   
Sbjct: 156 PGFAVQNPLVGPHDDRYGARFVPMSKPYDRKLRDIFKQTIDGMSMAGLHSPFRTGVYAMV 215

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN--MAEGLSDVKL 249
            GP +E+ AE R ++  G D VGMS VPEVI A    +K +A+S ITN  + +   D + 
Sbjct: 216 GGPTYESPAEARFIKSAGADAVGMSTVPEVIVAIQQGVKCLAMSLITNKVVLKIDDDNEP 275

Query: 250 SHAQTLAAAELSKQNFINLICGFLRKI 276
           +HA+ L A++  + +   L     + +
Sbjct: 276 NHAEVLEASQARQPDVQRLFVALSKNV 302


>UniRef50_B7A7P1 Inosine guanosine and xanthosine phosphorylase family n=3
           Tax=Thermaceae RepID=B7A7P1_THEAQ
          Length = 276

 Score =  183 bits (465), Expect = 5e-45,   Method: Compositional matrix adjust.
 Identities = 97/256 (37%), Positives = 146/256 (57%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           K  F P V  +LGSGLG LA+++E    + Y ++P FP+ST  GHAG LVLG L+G  V+
Sbjct: 20  KTGFAPEVGIVLGSGLGPLAEEVEKVAEMPYGEIPHFPLSTAPGHAGRLVLGTLEGKRVL 79

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
             +GR H+YEG     +   +R    LG      T+AAG L P   AG ++   D++N  
Sbjct: 80  VYQGRVHYYEGYSAEEVVFPVRVGFFLGARTFLLTSAAGGLNPRFQAGGIMLHLDYLNPS 139

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAA 200
              P+ G ND+R G RF  +  AYD E   L ++VA+++   L EGV+  + GP+F + A
Sbjct: 140 GVNPLRGKNDERLGPRFPVMFGAYDPELVELARRVARKQDLHLFEGVYAWFLGPSFASRA 199

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAEL 260
           E++M++ +G D +GMS VPEVI+ RH   +V+ +S IT+MA    +   +  + L  A  
Sbjct: 200 ELKMLRELGADAIGMSTVPEVIALRHLGARVLGLSTITDMAVPEREHHATEEEVLEVARR 259

Query: 261 SKQNFINLICGFLRKI 276
           +   F   + G L ++
Sbjct: 260 TGPVFRRFVRGILAEL 275


>UniRef50_Q3B5L6 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=48 Tax=Bacteria RepID=Q3B5L6_PELLD
          Length = 302

 Score =  182 bits (463), Expect = 7e-45,   Method: Compositional matrix adjust.
 Identities = 96/227 (42%), Positives = 131/227 (57%), Gaps = 1/227 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +  I+    D  P V  +LG+GLGALA +I+   A+ Y  +P FP+STV  H G+L+ G
Sbjct: 40  AVSFIRKKTQDEYP-VGIVLGTGLGALAKEIDVEFALDYADIPNFPISTVETHHGKLIFG 98

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L G  VV M+GR HFYEG  M  +   IR  K LG + L  TNA G L P    G ++ 
Sbjct: 99  TLAGRKVVAMQGRFHFYEGYSMQQIVFPIRVMKHLGVKTLGITNACGGLNPGFQKGDIML 158

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN +PG P++G ND   G RF  +   Y      + ++VA E    +  GV+++  
Sbjct: 159 IDDHINMLPGNPLIGHNDPETGSRFPDMCEPYSKRLLKIAEEVALEHKIKVQRGVYIALS 218

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
           GP  ET AE RM++ +G DVVGMS VPEVI+A H   +V  +S IT+
Sbjct: 219 GPCLETRAEYRMLRTLGADVVGMSTVPEVIAAVHQGTEVFGMSIITD 265


>UniRef50_C1C0Q7 Purine nucleoside phosphorylase n=2 Tax=Caligus RepID=C1C0Q7_9MAXI
          Length = 299

 Score =  181 bits (458), Expect = 3e-44,   Method: Compositional matrix adjust.
 Identities = 95/257 (36%), Positives = 148/257 (57%), Gaps = 9/257 (3%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P +  I GSGLG++ D +++ V I Y  +P FP +TV  H  ++V G L G  V+ M+GR
Sbjct: 33  PTIGIICGSGLGSIGDAVKDPVIIKYTDIPHFPTTTVGSHRSQMVFGTLGGAQVMVMQGR 92

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM----P 141
            HFYEG  +   +  +R   L+G + L  TNA+G  R ++  G L+ + DHIN +     
Sbjct: 93  FHFYEGHSIHTCSMPVRVMHLVGVKTLISTNASGGTREDLKVGDLLIMTDHINLLGFNGG 152

Query: 142 GTPMVGLN-DDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNFET 198
             P+ G N D+RFG RF ++   YD EY  L +++AK+ G    +  GV+    GP++ET
Sbjct: 153 QNPLGGANHDNRFGTRFVAMNKCYDEEYIKLARQIAKDSGLESIVKSGVYAMTGGPSYET 212

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM--AEGLSDVKLSHAQTLA 256
            AE+R M+I+GGD +GMS V E I AR C ++V ++S ITN+  +   S+ K +H + + 
Sbjct: 213 PAEVRSMKILGGDCIGMSTVHENIVARQCGMRVFSMSLITNICVSSQESEDKATHQEVIE 272

Query: 257 AAELSKQNFINLICGFL 273
             +  +++       FL
Sbjct: 273 VGQSREESLKIFTFSFL 289


>UniRef50_A7S700 Predicted protein n=3 Tax=cellular organisms RepID=A7S700_NEMVE
          Length = 295

 Score =  180 bits (456), Expect = 5e-44,   Method: Compositional matrix adjust.
 Identities = 106/264 (40%), Positives = 144/264 (54%), Gaps = 8/264 (3%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           +  + P +  I GSGL +L D +     I YEK+P FP STV GH G+LV G L G  VV
Sbjct: 31  QTSYQPTIGVICGSGLSSLGDLVTEKTVIPYEKIPQFPRSTVPGHQGQLVFGRLNGTTVV 90

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
            M+GR H YEG     +T  +R    LG + L  TNAAG LR +   G ++ +KDHIN  
Sbjct: 91  MMQGRTHLYEGYDPGQITLPVRVMVHLGIKHLVVTNAAGGLRQDWNVGDIMVIKDHINLA 150

Query: 141 PGT---PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPN 195
             T   P+ G ND RFG RF +L++AY+ + + L  + A E GF      GV+ +  GP 
Sbjct: 151 GLTGLSPLRGCNDSRFGLRFPALSDAYNKDLQKLALETASELGFADFTRTGVYCAQVGPC 210

Query: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA---EGLSDVKLSHA 252
           FET AE R +Q  G D VGMS V EV  ARH  + V+ +S ITN+A    G ++   +H 
Sbjct: 211 FETPAECRFLQNAGVDAVGMSTVHEVSVARHAGVTVLGISLITNIAVLGYGDNEQPANHD 270

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           + L        +   L+   L+K+
Sbjct: 271 EVLETGRRRASDMQKLVSTILQKL 294


>UniRef50_A4CJ72 Purine nucleoside phosphorylase n=15 Tax=Bacteroidetes
           RepID=A4CJ72_9FLAO
          Length = 271

 Score =  180 bits (456), Expect = 5e-44,   Method: Compositional matrix adjust.
 Identities = 95/252 (37%), Positives = 145/252 (57%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
            P +  +LGSGLG +AD++E++    Y  +P FP++TV  H+G+L  G + G  VV M+G
Sbjct: 20  NPEIGIVLGSGLGRMADELEDSRVAHYHNIPNFPLATVEFHSGKLFCGTIHGKKVVVMQG 79

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H YEG     +T  IR  + LG   L  +NAAG++  +   G L+ + DHIN   G+P
Sbjct: 80  RFHLYEGYDFFDITYPIRVMERLGIRKLLISNAAGAVNLDFQKGDLMLITDHINLQGGSP 139

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           +   N   FGERF  ++  YD E +  ++++AK     L EGV+ +  GP  ET AE RM
Sbjct: 140 LAFKNVADFGERFVDMSCPYDREMQGRIREIAKGTDCVLREGVYAAVFGPQLETRAEYRM 199

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           +  +G D VGMS VPEVI A H  L V A+S IT++ +  +   ++  + LA A  ++  
Sbjct: 200 LGRLGADAVGMSTVPEVIVANHLKLPVAAISVITDLGDPDNLEPVNVTEILAVAARAEPG 259

Query: 265 FINLICGFLRKI 276
            + ++   +R+I
Sbjct: 260 LVRIMKELIREI 271


>UniRef50_Q05788 Purine nucleoside phosphorylase n=10 Tax=Saccharomycetaceae
           RepID=PNPH_YEAST
          Length = 311

 Score =  177 bits (450), Expect = 3e-43,   Method: Compositional matrix adjust.
 Identities = 110/272 (40%), Positives = 149/272 (54%), Gaps = 25/272 (9%)

Query: 26  PRVAFILGSGLGALADQIEN----AVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVC 81
           PR   I GSGLG ++ ++       V + Y+ +PGF  STV GH+G L+ G + G PVV 
Sbjct: 38  PRTLIICGSGLGGISTKLSRDNPPPVTVPYQDIPGFKKSTVPGHSGTLMFGSMNGSPVVL 97

Query: 82  MKGRGHFYEGRGMTIMTDAIRTFKLLG-CELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
           M GR H YEG  +   T  IR    +G    L  TNAAG +  +  A  L+ + DH+N +
Sbjct: 98  MNGRLHGYEGNTLFETTFPIRVLNHMGHVRNLIVTNAAGGINAKYQACDLMCIYDHLN-I 156

Query: 141 PGT----PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF--PLTEGVFVSYPGP 194
           PG     P+ G N D  G RF +L++AYD E R LL K  KE     PL EG +    GP
Sbjct: 157 PGLAGQHPLRGPNLDEDGPRFLALSDAYDLELRKLLFKKWKELKIQRPLHEGTYTFVSGP 216

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM------AEGLSDV- 247
            FET AE +M++++GGD VGMS VPEVI ARHC  +V+A+S ITN       A  L +  
Sbjct: 217 TFETRAESKMIRMLGGDAVGMSTVPEVIVARHCGWRVLALSLITNTCVVDSPASALDESP 276

Query: 248 ------KLSHAQTLAAAELSKQNFINLICGFL 273
                 K +HA+ L   +++  +  NLI   +
Sbjct: 277 VPLEKGKATHAEVLENGKIASNDVQNLIAAVM 308


>UniRef50_Q311R2 Inosine guanosine and xanthosine phosphorylase n=4
           Tax=Desulfovibrio RepID=Q311R2_DESDG
          Length = 276

 Score =  176 bits (447), Expect = 6e-43,   Method: Compositional matrix adjust.
 Identities = 93/218 (42%), Positives = 122/218 (55%), Gaps = 2/218 (0%)

Query: 22  PDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVC 81
           PD  P+V  +LG+GLG L D +     I Y ++P FP STV  H G  + G +   PV+ 
Sbjct: 22  PD--PKVGIVLGTGLGGLVDAVSIHTVIDYGEIPDFPRSTVASHQGRFIAGSIGSTPVLL 79

Query: 82  MKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMP 141
            +GR H YEG     +   +RT    G + L  TNAAG+L P   AG L+A+ DHIN   
Sbjct: 80  QQGRCHLYEGYSAGDVCTGVRTMAACGADTLIITNAAGALNPAWSAGDLMAITDHINFTG 139

Query: 142 GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAE 201
            +P+ G N+D +G RF  ++  YDA+      + A E G  L  GV+    GP  ET AE
Sbjct: 140 QSPLTGPNNDLWGPRFPDMSAPYDAQLICAAMQKASELGIRLERGVYAGVRGPQMETPAE 199

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
            RM +  G D VGMS V EVI+ARH  LKV+ VS +TN
Sbjct: 200 TRMYKAAGADAVGMSTVLEVIAARHMGLKVLGVSCLTN 237


>UniRef50_C7LVA5 Inosine guanosine and xanthosine phosphorylase family n=2
           Tax=Desulfovibrionales RepID=C7LVA5_DESBD
          Length = 278

 Score =  175 bits (444), Expect = 1e-42,   Method: Compositional matrix adjust.
 Identities = 103/268 (38%), Positives = 139/268 (51%), Gaps = 5/268 (1%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
           L   + IK   P   P+   +LGSGLG          +I Y  +PGFPVSTV GHAG L+
Sbjct: 9   LTATEWIKNNCPS-APKTGLVLGSGLGKWIKPAWIQKSIPYSDIPGFPVSTVEGHAGALL 67

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
           +  ++G PV    GR H YEG     +T  I    LLG   L  TNAAG+L P    G L
Sbjct: 68  VAEIKGTPVFIFSGRFHLYEGYRPQEVTLPIVCLALLGAGNLILTNAAGALNPLFATGGL 127

Query: 131 VALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVS 190
           + L DHIN     P+ G N D +G RF  ++  Y    R    +     G  L +GV+V+
Sbjct: 128 MLLTDHINMTGHNPLTGPNVDAWGPRFPDMSQVYCPTLREQAMQAGLACGQRLEQGVYVA 187

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD--VK 248
             GP+ ET AE RM +I+G D +GMS  PE I+A H  LKV+ +S +TN  + L D   +
Sbjct: 188 VAGPSLETPAETRMYRIMGADAIGMSTAPEAITAHHMGLKVLGISCLTN--KNLPDCMAE 245

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKI 276
            SHA+ L+ A  S     +L+   +  +
Sbjct: 246 TSHAEILSQANASADALGSLLSALIPNL 273


>UniRef50_B1GZW7 Purine nucleoside phosphorylase n=1 Tax=uncultured Termite group 1
           bacterium phylotype Rs-D17 RepID=B1GZW7_UNCTG
          Length = 281

 Score =  174 bits (440), Expect = 4e-42,   Method: Compositional matrix adjust.
 Identities = 89/237 (37%), Positives = 131/237 (55%)

Query: 23  DFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM 82
           DF P  A I GSGLG ++ Q      I Y  +P F  + V GHAG+L+L       ++  
Sbjct: 21  DFNPTTAVIAGSGLGEISKQFTIRKTIKYSDIPYFLKTAVQGHAGDLLLCSYGSADLLIF 80

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            GR H+YEG     +   +R  K LG + L  T A G L  +   G ++ LKDHI+    
Sbjct: 81  NGRFHYYEGHHPQEVVYPVRVMKFLGIKTLVITAATGGLNKKYSVGDIIVLKDHIDCTGN 140

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEI 202
            P++G++ D FGERF ++ N YDA  R     +AK+      EG++    GP++ET A +
Sbjct: 141 NPLIGVHYDEFGERFPNMENVYDAVLRKKALSLAKKFKIKACEGIYFGVSGPSYETPASV 200

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAE 259
           +  QI+GGDVVGMSVV E   A    ++V+ ++ ++NMA G+ +  LSHA+ +   E
Sbjct: 201 KAYQILGGDVVGMSVVYEATVAAQMKMRVLGLAYVSNMAAGIHNRPLSHAEVIENGE 257


>UniRef50_B6K0G6 Purine nucleoside phosphorylase n=1 Tax=Schizosaccharomyces
           japonicus yFS275 RepID=B6K0G6_SCHJY
          Length = 319

 Score =  174 bits (440), Expect = 4e-42,   Method: Compositional matrix adjust.
 Identities = 98/223 (43%), Positives = 131/223 (58%), Gaps = 10/223 (4%)

Query: 26  PRVAFILGSGLGALADQIEN-AVAISYEKLPGFPVSTVHGHAGELVLGHL--QGVPVVCM 82
           PRVA + GSGLG+LA+ +      I Y  +PGF    + GHA  L+   +    VP +  
Sbjct: 45  PRVAVVCGSGLGSLAENLFGPKFVIPYSDIPGFVACHIPGHASRLIFAFIGENKVPCMIF 104

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            GR H YEG  + ++T   R  K++G E++  TNAAG L      G L+ +KDHIN  PG
Sbjct: 105 AGRFHSYEGHALDVVTFPQRFMKIMGVEVMIATNAAGGLNSNYKVGELMIIKDHIN-FPG 163

Query: 143 ----TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT--EGVFVSYPGPNF 196
                P+ G N D FG RF  L++AYD E R L+ K A E     T  EG +    GP+F
Sbjct: 164 LAGLNPLKGPNLDDFGTRFPPLSDAYDLELRKLVYKAATERDVHRTINEGCYAFVSGPSF 223

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
           ET AE RM++++G D VGMS VPEVI ARHC ++V+A+S +TN
Sbjct: 224 ETRAEARMLKLLGADCVGMSTVPEVIVARHCGIRVLAISLVTN 266


>UniRef50_B8ICG2 Purine nucleotide phosphorylase n=28 Tax=Alphaproteobacteria
           RepID=B8ICG2_METNO
          Length = 286

 Score =  173 bits (438), Expect = 6e-42,   Method: Compositional matrix adjust.
 Identities = 102/246 (41%), Positives = 135/246 (54%), Gaps = 3/246 (1%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +A + G+GLG LA +IE    + Y ++P FPVS V GHAG+LV G L G PV+  +GR H
Sbjct: 36  LAVVAGTGLGPLAARIEAPRILPYAEIPHFPVSGVSGHAGQLVAGDLGGRPVLLFQGRAH 95

Query: 88  FYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG 147
            YE      M   +     LG   L  TNAAGSLR E G G L  + DH+N     P++G
Sbjct: 96  AYEQGDAAAMRVPLGVLAALGAPPLLLTNAAGSLRHEAGPGRLALITDHLNLSGLNPLIG 155

Query: 148 LNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQI 207
            + +    RF  + +AYD   R  L   A      L EGV+  + GP+FET AEIRM   
Sbjct: 156 EHSE---ARFVPMVDAYDPGLRKSLHGAAAAADLVLHEGVYAWFLGPSFETPAEIRMAGR 212

Query: 208 IGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFIN 267
           +G D+VGMS VPEVI AR   L+V A+S +TN A G       HA+T   A  + ++   
Sbjct: 213 LGADLVGMSTVPEVILARFFGLRVAALSIVTNYAAGFDGGAPHHAETKRVAAAAAEDVGR 272

Query: 268 LICGFL 273
           L+  +L
Sbjct: 273 LLAVWL 278


>UniRef50_A9BH77 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=9 Tax=Bacteria RepID=A9BH77_PETMO
          Length = 270

 Score =  171 bits (433), Expect = 3e-41,   Method: Compositional matrix adjust.
 Identities = 93/237 (39%), Positives = 131/237 (55%)

Query: 38  ALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIM 97
            +ADQ+EN   I Y+ +P FP STV GH G LV+G ++G+PV+ +KGR H YEG  +  +
Sbjct: 32  YIADQVENPKVIEYKDIPFFPQSTVVGHEGSLVIGTIEGIPVMILKGRFHAYEGIELKDI 91

Query: 98  TDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERF 157
              I   K LG + L  TNAAG +      G +V   D IN     P+ G N D FG RF
Sbjct: 92  VFPIYVMKDLGVKGLIITNAAGGINKTFSPGDIVVDVDFINFTFKNPLRGPNLDEFGPRF 151

Query: 158 FSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSV 217
            SL    D  +   + +  K++   L EG ++   GP++ET +EIRM      D+VGMS 
Sbjct: 152 PSLVEPVDKNWVKSVIEKCKKDNIELKEGTYLWTLGPSYETPSEIRMFDKYEADLVGMST 211

Query: 218 VPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLR 274
           +PEV++A H  LKV++ SA+TNMA G+    L H   L   E  K  F  ++   ++
Sbjct: 212 LPEVMAANHVGLKVISFSAVTNMAAGILPQPLKHEDVLRITEKIKGKFEKVVYNAIK 268


>UniRef50_C7NVB1 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Halorhabdus utahensis DSM 12940 RepID=C7NVB1_HALUD
          Length = 275

 Score =  169 bits (429), Expect = 6e-41,   Method: Compositional matrix adjust.
 Identities = 94/253 (37%), Positives = 137/253 (54%), Gaps = 1/253 (0%)

Query: 24  FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
            TP  A ILGSGLG + D++E  +++ YE +P    STV GHAG  V+G +  V V+ M 
Sbjct: 18  LTPETAMILGSGLGGMTDEMEIELSVPYEDVPTLEASTVEGHAGRFVVGTVGEVSVLGMD 77

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           GR H+YE   M  +   IR    LGCE L  TNAAG +  +   G ++ ++DHIN     
Sbjct: 78  GRVHYYETGDMDPIVAPIRALGELGCERLLITNAAGGINADYEPGDVMLIEDHINMQGTN 137

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEI 202
           P++G      G  F  + NAY  +  A  + +A +    + + GV+   PGP++ET AEI
Sbjct: 138 PLIGRAGLGDGPMFPDMTNAYSPDLLAAARDLAADSSLTIHDGGVYAGMPGPSYETPAEI 197

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
            M+  +G D VGMS VPEVI A    + VV +S ITN A G+    LSH + +   +  +
Sbjct: 198 EMLDTVGADAVGMSTVPEVIVANQLGMDVVGMSTITNYAAGVVGDPLSHEEVVETIKTIE 257

Query: 263 QNFINLICGFLRK 275
            +    +   L++
Sbjct: 258 DDLRTYVTALLQR 270


>UniRef50_B3QTH8 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Chloroherpeton thalassium ATCC 35110
           RepID=B3QTH8_CHLT3
          Length = 292

 Score =  169 bits (428), Expect = 9e-41,   Method: Compositional matrix adjust.
 Identities = 91/239 (38%), Positives = 135/239 (56%), Gaps = 6/239 (2%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           VA +LGSGLGA A +++   +    ++P FP  +V GH G +  G L   PV  ++GR H
Sbjct: 45  VAIVLGSGLGAFASRVKVYHSFKTSEIPHFPTPSVEGHGGRVTFGTLGDRPVALIEGRVH 104

Query: 88  FYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG 147
            YEG  +  +T  +   + LG ++L  TN+AG + P+   G L  ++DHIN M  T +  
Sbjct: 105 LYEGWPVEWVTFYVEILRQLGIKVLILTNSAGGINPDFNVGDLCLIRDHINFMFETRL-- 162

Query: 148 LNDDRFG-ERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQ 206
              +R+G E        YD +   ++ + A E    L +GV+    GP +ET AEIRM+Q
Sbjct: 163 ---NRYGMEPRLRHVGFYDKDLSEVIYRTANECKITLRQGVYAGVKGPCYETKAEIRMLQ 219

Query: 207 IIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNF 265
             G D+VGMS VPEV++A    ++V AVS +TN A G+S+ KLSH      AE +++ F
Sbjct: 220 ACGADLVGMSTVPEVVAANFHHMRVAAVSLVTNKATGISECKLSHDDVKKTAESAREKF 278


>UniRef50_B8J4B5 Inosine guanosine and xanthosine phosphorylase family n=7
           Tax=Desulfovibrionales RepID=B8J4B5_DESDA
          Length = 303

 Score =  169 bits (428), Expect = 1e-40,   Method: Compositional matrix adjust.
 Identities = 89/226 (39%), Positives = 128/226 (56%), Gaps = 9/226 (3%)

Query: 23  DFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH--------- 73
           D +  V  +LG+GL  LAD++   VA+ Y  LPGFPVS+V  H G  V G          
Sbjct: 41  DNSVPVGLVLGTGLSGLADRLAERVAVPYADLPGFPVSSVDSHVGAFVWGRFPSSCGEDD 100

Query: 74  LQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVAL 133
           + G PV+  +GR H YEGR    +   +R    +G + L  TNAAG+L P   AGS++ +
Sbjct: 101 VPGRPVLIQQGRCHLYEGRSPAEVCMGVRVMAAMGVKTLVITNAAGALNPHFDAGSIMCM 160

Query: 134 KDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPG 193
            D IN    +P++G N +++G RF  ++  +DA+ R L  + +   G  L  GV++   G
Sbjct: 161 SDFINHTGYSPLLGCNCEQWGPRFPDMSAPFDADLRTLAMETSARLGLRLERGVYIGVRG 220

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
           P  ET AE RM +  G D VGMS V EVI+ARH  ++V+ +S I+N
Sbjct: 221 PEMETPAETRMYRQWGADAVGMSTVLEVIAARHLGMRVLGLSCISN 266


>UniRef50_Q9UTG1 Putative purine nucleoside phosphorylase n=4 Tax=Ascomycota
           RepID=PNPH_SCHPO
          Length = 315

 Score =  168 bits (425), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 100/223 (44%), Positives = 129/223 (57%), Gaps = 10/223 (4%)

Query: 26  PRVAFILGSGLGALADQIENAV-AISYEKLPGFPVSTVHGHAGELVLGHL--QGVPVVCM 82
           P+VA I GSGLG LA  +   V  + YE +P F VS V GHA +L    L  + VP + +
Sbjct: 41  PKVAIICGSGLGTLASGLSAPVYEVPYEDIPHFHVSHVPGHASKLYFAFLGEKRVPTMIL 100

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            GR H YEG  +   T  +R  K++G E++  TNAAG L      G L+ LKDHIN  PG
Sbjct: 101 AGRYHSYEGYPIEATTFPVRLMKVMGVEVMVVTNAAGGLNQGFKVGDLMILKDHIN-FPG 159

Query: 143 ----TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT--EGVFVSYPGPNF 196
                P+ G N   FG RF  L++AYD E R L+   AK      T  EG +    GP F
Sbjct: 160 LAGMNPLRGPNAHEFGVRFPPLSDAYDLELRKLVYDAAKAHKVSRTIHEGCYAFVSGPCF 219

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
           ET AE RM+ ++G D VGMS VPEV+ ARHC ++V+A+S +TN
Sbjct: 220 ETRAESRMLALMGADCVGMSTVPEVVVARHCGIRVLAISLVTN 262


>UniRef50_Q2CJ93 Purine nucleoside phosphorylase n=1 Tax=Oceanicola granulosus
           HTCC2516 RepID=Q2CJ93_9RHOB
          Length = 276

 Score =  167 bits (423), Expect = 4e-40,   Method: Compositional matrix adjust.
 Identities = 94/224 (41%), Positives = 133/224 (59%), Gaps = 8/224 (3%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           + D  P +A  LGSGLG LAD ++    I Y  +P FPVSTV GH G L++G L G   V
Sbjct: 16  RTDMVPEIALTLGSGLGPLADHLDGTT-IPYADIPHFPVSTVQGHDGVLMVGTLFGRACV 74

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
            M+GR H YEG     +   +R    LG +    TNAAG +   +  G LVA++DH++  
Sbjct: 75  AMRGRVHMYEGYSAQEVAFPMRVMAALGAQTAIFTNAAGGMGEGMQVGDLVAIEDHLSLA 134

Query: 141 PGT---PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFE 197
             +   P+ G ND   GERF S+  AYD E   L+Q ++ +    +  GV+    GP+FE
Sbjct: 135 VASGHDPLRGPNDPGIGERFVSMNRAYDPELIDLVQSLSPD----IARGVYGHLVGPSFE 190

Query: 198 TAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA 241
             A IR++++ G D+ GMS VPEVI+ARH  ++V+A+SA+TN+A
Sbjct: 191 PPALIRLLKLAGVDLAGMSTVPEVIAARHMGVRVLALSAVTNIA 234


>UniRef50_B4MDV7 GJ18292 n=4 Tax=Drosophila RepID=B4MDV7_DROVI
          Length = 325

 Score =  166 bits (421), Expect = 6e-40,   Method: Compositional matrix adjust.
 Identities = 97/258 (37%), Positives = 138/258 (53%), Gaps = 20/258 (7%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           + +  P+   + GS L  L D IEN + I Y  +P FP  T+H H G+L +G L G  V+
Sbjct: 63  RSETRPKFGLVCGSNLDTLTDLIENPIVIDYSDIPKFPDCTIHDHKGKLFVGTLMGATVI 122

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN-- 138
            ++GR H YEG  +   +  +R  KL G E +  T AAG++      G ++ +KDHIN  
Sbjct: 123 ALQGRFHHYEGNSLASCSMPVRVLKLCGIEYMILTCAAGAVNKNYKVGDIMLIKDHINMF 182

Query: 139 -TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE------GVFVSY 191
                 P+ G ND RFG+R   +A+AYD     L++K A E G  + +      GV+   
Sbjct: 183 GWFGNNPLNGPNDLRFGDRHVIMADAYD---EGLIEK-ALEIGLEIGQEDRMHLGVYACL 238

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT-------NMAEGL 244
            GP +ETA E R ++ IG D VGMS+V EVI ARHC LKV + S I+       +M E +
Sbjct: 239 GGPVYETATEQRFLRSIGVDAVGMSLVQEVIYARHCGLKVFSFSLISMPPIEQPDMPESV 298

Query: 245 SDVKLSHAQTLAAAELSK 262
            DV +   Q +    LS+
Sbjct: 299 RDVSIHQGQIVCMELLSR 316


>UniRef50_D2QX63 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Pirellula staleyi DSM 6068 RepID=D2QX63_9PLAN
          Length = 279

 Score =  164 bits (415), Expect = 3e-39,   Method: Compositional matrix adjust.
 Identities = 104/269 (38%), Positives = 153/269 (56%), Gaps = 6/269 (2%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
           L   +I K Y    TPRVA ILG+GLG LA +IE A  I Y+++PGFP ST   H G L+
Sbjct: 12  LAAAEIRKHYTE--TPRVAVILGTGLGGLASEIEAAAEIPYKQIPGFPHSTAPAHKGRLL 69

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
           LG+L G+P   + GR HFYEG  +  +       + LGC+ L  +NAAG + P    G +
Sbjct: 70  LGNLLGLPCAMLAGRCHFYEGYQLEQLMFPTLVMRELGCQYLIVSNAAGGVNPLYETGDV 129

Query: 131 VALKDHINTM--PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVF 188
           + + DHIN M   G+  V        ERF    + YD    ++ +  A +EGF    GV+
Sbjct: 130 MLMDDHINLMYFKGSVAVPAASPERVERFQE--HLYDRALLSMAESAAIQEGFIPKRGVY 187

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK 248
           V+  GP +ET AE R+ + IGGDVVGMS VPEV++A    ++V+ +S +TN+A+  +   
Sbjct: 188 VAVSGPTYETRAEYRLFRRIGGDVVGMSTVPEVLAATSVGMRVMGISTVTNVAKPDAMQT 247

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKIA 277
           +S  + +  AE  +    +++ G + +IA
Sbjct: 248 VSSDEVIDVAERVQHKVRSIVRGVIERIA 276


>UniRef50_B7GAT6 Predicted protein (Fragment) n=2 Tax=Bacillariophyta
           RepID=B7GAT6_PHATR
          Length = 262

 Score =  162 bits (409), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 92/256 (35%), Positives = 139/256 (54%), Gaps = 13/256 (5%)

Query: 26  PRVAFILGSGLGALADQIEN-AVAISYEKLPGFPV-STVHGHAGELVLGHLQGVPVVCMK 83
           P V  I GSGL  LA  ++   + + Y  +PGFP   TV GH GE+V G + GV  +C +
Sbjct: 1   PTVGIICGSGLSGLAATLDGPTLTVPYADIPGFPAHCTVAGHKGEVVFGSIHGVQAICFR 60

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMP-- 141
           GR H YEG  M  +   +   + L  +++  TNAAG L P+   G +VA+ DH+  +P  
Sbjct: 61  GRFHSYEGHDMKTVVLPVYVMRCLDTKIVIITNAAGGLNPDYNVGDVVAVSDHL-ALPQL 119

Query: 142 --GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE---EGFPLTEGVFVSYPGPNF 196
               P++G NDD  G RF + ++AY    R      A+    + +    G +    GP +
Sbjct: 120 AGKNPLIGPNDDELGPRFPATSDAYPDALRIAATHAAESLNMQEYWHPHGTYCFVSGPMY 179

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN--MAEGLSDVKL-SHAQ 253
           E+ AE R+++ +GGD VGMS +PEV++A HC+LKV+ +S ITN  + EG     + +HA+
Sbjct: 180 ESKAECRLLRTLGGDAVGMSTIPEVVAAHHCELKVLCLSLITNKVVMEGDEGATVATHAE 239

Query: 254 TLAAAELSKQNFINLI 269
            L A +        L+
Sbjct: 240 VLEAVQARSVQMQTLV 255


>UniRef50_C5NWB5 Purine nucleoside phosphorylase 1 n=1 Tax=Gemella haemolysans ATCC
           10379 RepID=C5NWB5_9BACL
          Length = 274

 Score =  161 bits (408), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 92/252 (36%), Positives = 134/252 (53%), Gaps = 7/252 (2%)

Query: 29  AFILGSGLGALADQIENAVAISYEKLPGFP----VSTVHGHAGELVLGHLQGVPVVCMKG 84
           A +LGSG+     ++E+   + YE +P FP     + V GHA +L  G + G  V+ + G
Sbjct: 25  AVVLGSGITL---ELEDQQELGYEAIPLFPGNKHANRVKGHANKLTFGKISGKNVLVLNG 81

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H+YEG  M  +       K LG + LF TNA G++      G +V L D I+ +   P
Sbjct: 82  RLHYYEGYSMKDVAFMTYVVKHLGVKGLFITNACGAINTNFREGDIVCLDDFISLVSNNP 141

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           ++G N+ R GERF  +   +D+     L K AK+    L  GV+  + GP FET AEIR 
Sbjct: 142 LMGENEPRLGERFVDMTTPFDSYLVENLHKSAKKLDITLHTGVYGFFQGPYFETRAEIRA 201

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
            + +G D+VGMS VPEVI+A H  L V  ++  TNMA G+ + K  H   L  A+   +N
Sbjct: 202 FKTMGCDLVGMSTVPEVIAANHASLPVAVLACATNMATGIQEKKHDHEHVLQTAQKISEN 261

Query: 265 FINLICGFLRKI 276
              L+   L+ +
Sbjct: 262 LKKLLIETLQNL 273


>UniRef50_B9ZYX1 Nucleoside phosphorylase n=1 Tax=Dicyema japonicum
           RepID=B9ZYX1_9METZ
          Length = 282

 Score =  161 bits (407), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 7/225 (3%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQ-GVPV 79
           K    P V  + G+GLG + + I +   + +  +P  P +TV  HAG+ VLG L  G  V
Sbjct: 20  KMTIRPTVGIVCGTGLGGINEVINDKEIVKFSDIPNLPQTTVTSHAGQFVLGRLPCGKEV 79

Query: 80  VCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINT 139
           +  +GR HFYEG   +I+   IR  KL+G E L  TNAAG L      G ++ +KDHI  
Sbjct: 80  MVQQGRYHFYEGHDQSIIVAPIRMMKLMGVETLILTNAAGGLNQSYSIGDIMVIKDHI-Y 138

Query: 140 MPG----TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGP 194
            PG    +P+VG ND RFGERF  + N YD E R  + K A++ G      G++ S  GP
Sbjct: 139 FPGFAGNSPLVGPNDKRFGERFPPIYNLYDRELRKKMLKCAEQLGMDFVRHGIYASVAGP 198

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
           ++ET  ++R +   G D VGMS   E I   H  LKVVA+S ++N
Sbjct: 199 HYETIFDMRFLLKNGCDAVGMSTSGEAICGAHIGLKVVAMSGVSN 243


>UniRef50_Q11M20 Inosine guanosine and xanthosine phosphorylase family n=2
           Tax=Alphaproteobacteria RepID=Q11M20_MESSB
          Length = 279

 Score =  159 bits (402), Expect = 9e-38,   Method: Compositional matrix adjust.
 Identities = 97/249 (38%), Positives = 133/249 (53%), Gaps = 4/249 (1%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           V  ILGSGLG LA  +++A  I Y ++  FPV T  GH G+LV+G L G  V  M+GR H
Sbjct: 26  VGIILGSGLGDLAQSVDDAEVIPYTEIEAFPVPTAPGHKGQLVIGTLHGRRVAVMQGRLH 85

Query: 88  FYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG 147
            YEGR    +       K LG   L  TNAA  L P    G ++ ++DH+N     P+VG
Sbjct: 86  LYEGRSPQDIALGPYLLKRLGSASLIVTNAASGLHPAYRPGDVMLIEDHLNFTGLNPLVG 145

Query: 148 LNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQI 207
            N    G RF  ++ AYD     L ++ A+    P+ +G++    GP+ ET AE R ++ 
Sbjct: 146 SNSPEIGLRFPDMSRAYDPALLDLAEEAAERALQPVHKGIYGGILGPSLETLAERRFLRA 205

Query: 208 IGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFIN 267
            G D VGMS V EVI+A H  L+V+ +SAITN A  + D +     T+  A  S  N   
Sbjct: 206 SGCDAVGMSTVTEVIAAVHGGLRVIGISAITNTA-AIGDRR---TDTIEEALTSAANCAE 261

Query: 268 LICGFLRKI 276
            I   LR++
Sbjct: 262 KIDAILRQL 270


>UniRef50_C5P2F4 Purine nucleoside phosphorylase, putative n=2 Tax=Coccidioides
           RepID=C5P2F4_COCP7
          Length = 344

 Score =  158 bits (400), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 112/298 (37%), Positives = 154/298 (51%), Gaps = 49/298 (16%)

Query: 13  CIDIIKTYKPD--FTPRVAFILGSGLGALADQIENA--VAISYEKLPGFPVSTVHGHAGE 68
            ++ +K + P+   TPRVA I GSGLG LAD I++   V   Y  +P FP STV GH G+
Sbjct: 13  ALNYLKPHLPEALRTPRVAVICGSGLGGLADTIDSKAKVEFDYRDIPNFPASTVPGHLGK 72

Query: 69  LVLGHLQG-VPVVCMKGRGH---------FYEGRGMTIMTDAIRTFKLLGCELLF----- 113
           LV G+L    P V M GR           FYEG  +  +T  +R FKLLG E++      
Sbjct: 73  LVFGYLGAETPAVLMVGRAQEIEADTAASFYEGHSIDKVTFPVRLFKLLGVEIMIGTGNE 132

Query: 114 -----------------CTNAAGSLRPEVGAGSLVALKDHI--NTMPGT-PMVGLNDDRF 153
                             TNA+G L  E   G +V + DHI    + G  P+ G N+D F
Sbjct: 133 HLLGKHKIQSPTKQLCTVTNASGGLNSEYAVGDVVLINDHIFLAGLAGLHPLRGPNEDEF 192

Query: 154 GERFFSLANAYDAE-----YRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQII 208
           G RF +L++AYD E     +RA  + +  E    + EGV+    GP     AE R ++ +
Sbjct: 193 GVRFPALSDAYDLELRRTAHRAWTKVIRVESKRRIHEGVYAFCAGPR----AECRFLRQL 248

Query: 209 GGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFI 266
           G D+VGMS VPE+I ARHC L+V+A+S +TN A  L+ V     + L   E ++ N I
Sbjct: 249 GADLVGMSTVPEIIVARHCGLRVLALSLVTNNAV-LTPVPRGDDRLLQETERAQLNRI 305


>UniRef50_Q3A2Z8 Xanthosine phosphorylase n=1 Tax=Pelobacter carbinolicus DSM 2380
           RepID=Q3A2Z8_PELCD
          Length = 273

 Score =  158 bits (400), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 87/242 (35%), Positives = 129/242 (53%), Gaps = 4/242 (1%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +A ILGSGLG +AD +E+     Y     FP   V GHAG L+ G L G  V+  +GR H
Sbjct: 28  LALILGSGLGQVADAVEDVKVWEYRDFSCFPAVAVAGHAGRLLAGTLHGRRVLIFQGRFH 87

Query: 88  FYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG 147
            Y+G         +R    LGC  L  TNA G + P++ AG  + + DHIN +   P+ G
Sbjct: 88  LYQGLTAWQTAVPVRLAHALGCRRLLLTNAVGGIHPDLDAGCFMFVADHINVLGDNPLRG 147

Query: 148 LNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQI 207
           +     G+ F  L+  Y  +    L+  A      + +GV  + PGP++ET AE+R ++ 
Sbjct: 148 M----CGDTFVDLSRLYRTDLFKSLRTEALSHNIHVQQGVLAAVPGPSYETPAEVRALRQ 203

Query: 208 IGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFIN 267
           +G D V MS++PE I A    L+VV +S++TN A GL   +L H + LA+   + +N   
Sbjct: 204 MGADAVSMSLIPEAIMAGALGLEVVGLSSVTNRAAGLGTKRLCHDEVLASGSNTAKNLSV 263

Query: 268 LI 269
           L+
Sbjct: 264 LV 265


>UniRef50_P46862 Purine nucleoside phosphorylase n=79 Tax=Actinomycetales
           RepID=PUNA_MYCLE
          Length = 268

 Score =  156 bits (395), Expect = 7e-37,   Method: Compositional matrix adjust.
 Identities = 91/249 (36%), Positives = 139/249 (55%), Gaps = 12/249 (4%)

Query: 28  VAFILGSGLGALADQIENAVAI-SYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           VA +LGSG  +    + ++ A+    +LPGF      GH GEL+   +    V+ + GR 
Sbjct: 30  VAVVLGSGWSSAVAALGSSRAVFPQAELPGFITPNAAGHTGELLSVRIGAHRVLVLAGRI 89

Query: 87  HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
           H YEG  +  +   +RT    G  ++  TNAAG LR ++  G LV + DH+N    +P+V
Sbjct: 90  HPYEGHDLRHVVHPVRTACAAGARIIVLTNAAGGLRADMAVGQLVLISDHLNLTTRSPLV 149

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQ 206
           G +       F  L NAY       L+K+A +    LTEGV+ + PGP++ET AEIRM++
Sbjct: 150 GTH-------FVDLTNAYTTR----LRKLASDTDPTLTEGVYAAQPGPHYETPAEIRMLR 198

Query: 207 IIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFI 266
           ++G D+VGMS V E I+AR    +V+ VS +TN+A G++   L+HA+ LAA   S     
Sbjct: 199 MLGADLVGMSTVHETIAARAAGAEVLGVSLVTNLAAGITGKPLNHAEVLAAGTASANRIG 258

Query: 267 NLICGFLRK 275
           +L+   + +
Sbjct: 259 SLLADIIAR 267


>UniRef50_Q2S0P3 Purine nucleoside phosphorylase n=1 Tax=Salinibacter ruber DSM
           13855 RepID=Q2S0P3_SALRD
          Length = 262

 Score =  156 bits (394), Expect = 9e-37,   Method: Compositional matrix adjust.
 Identities = 87/252 (34%), Positives = 137/252 (54%), Gaps = 1/252 (0%)

Query: 24  FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
           + P +A ILGSGLG LA+  +    +   ++PG+P STV GH+G+LV G L+   VV ++
Sbjct: 7   WAPEMALILGSGLGRLAEAADETTVVPAAEIPGYPESTVEGHSGKLVFGALEDTRVVFVQ 66

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           GR H YEG  +  +   +R    LG + +  TN+AG +      G+L+ +  H+N    +
Sbjct: 67  GRVHLYEGYPVQKIAMPVRLVHALGADRMLVTNSAGGINRTFDPGTLMFITSHLNMAFAS 126

Query: 144 PMVGLNDDRFGERF-FSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEI 202
           P VG       +R     A  Y+  + +  ++VA + G     G +    GP++ET AE+
Sbjct: 127 PGVGAGAGPARQRSDEEQAPFYEPGWTSRAEQVALDLGLDARRGTYAWTLGPSYETKAEV 186

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
           R ++ +G D VGMS VPEVI A    + V+ +S ITN A GL+   L H + L  +E  +
Sbjct: 187 RALEQLGADAVGMSTVPEVIQAHQLGMAVLGLSTITNPAAGLAPGGLDHDEVLEVSERVR 246

Query: 263 QNFINLICGFLR 274
            + + L+ G +R
Sbjct: 247 GDLMKLVRGIVR 258


>UniRef50_D2L8K6 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Desulfovibrio sp. FW1012B RepID=D2L8K6_9DELT
          Length = 300

 Score =  155 bits (393), Expect = 1e-36,   Method: Compositional matrix adjust.
 Identities = 95/277 (34%), Positives = 140/277 (50%), Gaps = 30/277 (10%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL---------QGV- 77
           V  + G+GLG +A ++E+   ++   +PGFP +T  GHAG LV G +         QG  
Sbjct: 26  VGLVAGTGLGGIAGKLEHCRDMATGDIPGFPAATAPGHAGRLVYGTMGTACPPGDPQGSI 85

Query: 78  ----------------PVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSL 121
                           PV  + GR H YEG     +   +R    LG   L  TNAAG+L
Sbjct: 86  EETMPAAGAGPDGSSRPVALLSGRLHLYEGHSPRDVAFGVRLLAALGVRQLILTNAAGAL 145

Query: 122 RPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF 181
            P   AG L+ + DH+N     P+VG NDD  G RF  ++ AY     A+    A   G 
Sbjct: 146 DPHFTAGGLMRVTDHLNLTGRNPLVGPNDDALGPRFPDMSRAYSPRLGAVADACALSLGL 205

Query: 182 PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT--N 239
            L  GV+    GP+ ET AE RM++++G D VGMS V EVI+ARH  ++V+AVS +T  N
Sbjct: 206 RLERGVYAGVLGPSLETPAETRMLRLLGADAVGMSTVTEVIAARHLGMEVLAVSCLTNVN 265

Query: 240 MAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           + + +++  L     LA A+ ++ +   L+   +  +
Sbjct: 266 LPDCMAETTLE--AVLATAKRAEGDLARLLAAVIPAV 300


>UniRef50_P81989 Purine nucleoside phosphorylase n=7 Tax=Actinobacteria (class)
           RepID=PUNA_CELSP
          Length = 282

 Score =  152 bits (383), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 91/256 (35%), Positives = 131/256 (51%), Gaps = 21/256 (8%)

Query: 28  VAFILGSGLGALADQIENAVA-ISYEKLPGFPVSTVHGHAG-------ELVLGHLQGVPV 79
           +A +LGSG G  A+ +   VA +   ++PGF    V GH         E   G ++    
Sbjct: 40  MALVLGSGWGGAAELLGEVVAEVPTHEIPGFSAPAVAGHLSVTRSIRVERADGSVRHA-- 97

Query: 80  VCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINT 139
           + +  R H YEG+G+  +   +RT    G E L  TN  G L  E GAG+ V L DHIN 
Sbjct: 98  LVLGSRTHLYEGKGVRAVVHGVRTAAATGAETLILTNGCGGLNQEWGAGTPVLLSDHINL 157

Query: 140 MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETA 199
              +P+        G  F  L + Y    R L  +V       L EGV+  +PGP++ET 
Sbjct: 158 TARSPL-------EGPTFVDLTDVYSPRLRELAHRVDPT----LPEGVYAQFPGPHYETP 206

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAE 259
           AE+RM  I+G D+VGMS   E I+ARHC L+V+ VS +TN+A G+S   LSHA+ + A +
Sbjct: 207 AEVRMAGILGADLVGMSTTLEAIAARHCGLEVLGVSLVTNLAAGISPTPLSHAEVIEAGQ 266

Query: 260 LSKQNFINLICGFLRK 275
            +      L+    ++
Sbjct: 267 AAGPRISALLADIAKR 282


>UniRef50_B0D4C6 Predicted protein n=3 Tax=Agaricales RepID=B0D4C6_LACBS
          Length = 315

 Score =  149 bits (377), Expect = 7e-35,   Method: Compositional matrix adjust.
 Identities = 92/227 (40%), Positives = 121/227 (53%), Gaps = 13/227 (5%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL---QGVPVVCM 82
           P +  I GSGL  LA+     V + YE +PGF  S+V GH   L  G L   +GVPVV M
Sbjct: 27  PNLGIICGSGLSGLAEDFRQVVIVPYEMIPGFGHSSVPGHKSALAFGLLGPGEGVPVVAM 86

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGS----LVALKDHI- 137
            GR H YEG  M+ +   +R    LG + L  TNAAGSL P +  G+    LV ++DHI 
Sbjct: 87  LGRFHPYEGHSMSTVIFPVRVMAKLGIKDLIITNAAGSLNPNIPVGTRKSFLVVIQDHIA 146

Query: 138 --NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF---PLTEGVFVSYP 192
             N     P++G        RF  L+NAY    R L    A +       L EG +    
Sbjct: 147 LPNLTGMNPLLGPQISSDVPRFLPLSNAYSPSLRRLAFLAAHQLSLDRSALAEGTYAWVS 206

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
           GP +ET AE R+++  G DVVGMS +PEV++AR   LKV+ +S +TN
Sbjct: 207 GPTYETPAEGRLLRNAGADVVGMSTIPEVLAAREAGLKVMVLSLVTN 253


>UniRef50_Q28ZG3 GA14805 n=2 Tax=pseudoobscura subgroup RepID=Q28ZG3_DROPS
          Length = 333

 Score =  141 bits (355), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 87/222 (39%), Positives = 123/222 (55%), Gaps = 12/222 (5%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPV-STVHGHAGELVLGHLQGVPVVCMKG 84
           PR+  I G  L  L D IE  V I +E +P FPV ST+ G    LV+G + G  V+ M+ 
Sbjct: 66  PRIGLICGHFLRQLVDIIEEPVLIPFEDIPQFPVCSTLEGARNHLVVGTVMGATVMAMQD 125

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM---P 141
           R H YEG  +      +R  KL G + +  T AA ++ P+   G ++ +KDHIN +    
Sbjct: 126 RFHTYEGYQLASSVLPVRVMKLCGVQHILLTCAAAAVNPQYAVGDIMLIKDHINMLGMFD 185

Query: 142 GTPMVGLNDDRFGERFFSLANAYDAEYRALLQK---VAKEEGFP--LTEGVFVSYPGPNF 196
            TP+ G +D RFG R  ++  AYD   R L++K   +  E GF   L  GVF    GP  
Sbjct: 186 RTPLTGAHDPRFGVRKLAMTRAYD---RHLIEKSLQIGGELGFDDCLQVGVFGCLCGPTC 242

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
           +T AE  M++++G D VGMS+V EVI + HC LK+ ++  IT
Sbjct: 243 KTNAEGEMLRVMGVDAVGMSLVHEVIVSHHCGLKIFSLGIIT 284


>UniRef50_D1BYW2 Purine nucleotide phosphorylase n=6 Tax=Actinomycetales
           RepID=D1BYW2_XYLCX
          Length = 283

 Score =  138 bits (348), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 87/257 (33%), Positives = 131/257 (50%), Gaps = 21/257 (8%)

Query: 28  VAFILGSGLGALADQIENAVA-ISYEKLPGFPVSTVHGHAG-------ELVLGHLQGVPV 79
           +A +LGSG G  A+ + + VA I   ++PGF   TV GH G       E   G  + V  
Sbjct: 40  IALVLGSGWGGAAELLGDVVAEIPSHEIPGFAKPTVAGHVGTTRSVCIERADGSTRNV-- 97

Query: 80  VCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINT 139
           + +  R H YEGRG+  +  A+RT    G   L  TN  G L      G +V ++DH+N 
Sbjct: 98  LVLGSRTHLYEGRGVRRVAHAVRTAAATGASALVLTNGCGGLHVSWRPGQVVLIRDHLNL 157

Query: 140 MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETA 199
              +P+ G         F  + + Y    R L + V       L EGV+  +PGP++ET 
Sbjct: 158 TATSPLEGAT-------FVDVTDLYTPRLRELARTVDPT----LPEGVYAQFPGPHYETP 206

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAE 259
           AE+R   I+G D+VGMS   E I+ARHC ++V+ +S +TN+A G+S   LSH + L A  
Sbjct: 207 AEVRAAGIMGADLVGMSTGLEAIAARHCGMEVLGMSLVTNLAAGVSPQPLSHEEVLEAGA 266

Query: 260 LSKQNFINLICGFLRKI 276
            +     +L+   ++ +
Sbjct: 267 KAGPVISDLLARIVKLV 283


>UniRef50_C5C9E7 Purine nucleotide phosphorylase n=3 Tax=Actinomycetales
           RepID=C5C9E7_MICLC
          Length = 301

 Score =  135 bits (341), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 86/252 (34%), Positives = 128/252 (50%), Gaps = 13/252 (5%)

Query: 27  RVAFILGSGLGALADQIENAVA-ISYEKLPGFPVSTVHGHAGELVLGHL-QGVPVVCMKG 84
           R+A +LGSG G  A  I + VA +   ++PGF    V GH   +    L  G   +    
Sbjct: 61  RIAVVLGSGWGEAAGLIGDEVAAVPLAEVPGFHAPKVPGHNAVIRSVRLPDGTHTLVFGS 120

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R HFYE R    +   +RT    G   +  TN  G + PE+  G+ V + DHIN    TP
Sbjct: 121 RTHFYESRDAQAVAHTVRTAAAAGARTVVLTNGCGGMDPEIAPGTPVLIADHINLTGATP 180

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           + G         F  L + Y    RA    +A+E    L EGV+V + GP +ET AE+RM
Sbjct: 181 LAGAT-------FVDLTDLYSPRLRA----IAREVDPSLREGVYVQFAGPQYETPAEVRM 229

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
            + +GGD+VGMS   + I+ARH  L+V  +S +TN+  G+S+  LSHA+ + A + +   
Sbjct: 230 ARTLGGDLVGMSTALDAIAARHAGLEVFGISLVTNLGAGISETPLSHAEVVEAGQAAGPR 289

Query: 265 FINLICGFLRKI 276
              L+   + ++
Sbjct: 290 IARLLADIVGRL 301


>UniRef50_Q7URV0 Purine nucleoside phosphorylase I n=1 Tax=Rhodopirellula baltica
           RepID=Q7URV0_RHOBA
          Length = 305

 Score =  135 bits (340), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 81/250 (32%), Positives = 123/250 (49%), Gaps = 17/250 (6%)

Query: 37  GALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTI 96
           G LAD IE+   + Y ++PG   ST  GH GE ++GHL   P++ M GR H YEG  +  
Sbjct: 48  GGLADAIESPTIVPYAEIPGLAPSTASGHRGEFLIGHLASRPIIAMAGRLHVYEGHSLRD 107

Query: 97  MTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMP---GTPMVGL----- 148
           +T  +     +G   L  + AAG L P+   G LV L +H + +    G P +       
Sbjct: 108 VTRPVALMAGIGINELVVSCAAGGLNPQFKVGDLVLLSEHSSWLDGKLGAPPISFQQPIS 167

Query: 149 ----ND-----DRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETA 199
               ND     D   + F    N  D +  A+  + A   GF L  G++++  GPN+ET 
Sbjct: 168 FQQPNDLPNESDAAAKCFRRSLNTCDPQLDAIAHQTAHANGFELRRGMYLAVNGPNYETR 227

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAE 259
           AE RMM+ +G D+VGMS VPE++ A    ++ + +S +TN+A   +     HA  L   E
Sbjct: 228 AECRMMRQLGADLVGMSTVPELLCANSAGVRTLGISVVTNLALPDAPATADHADVLEVCE 287

Query: 260 LSKQNFINLI 269
            +      ++
Sbjct: 288 RAANRLQQIV 297


>UniRef50_D2VAE0 Purine phosphorylase family protein n=1 Tax=Naegleria gruberi
           RepID=D2VAE0_NAEGR
          Length = 840

 Score =  135 bits (340), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 87/275 (31%), Positives = 138/275 (50%), Gaps = 26/275 (9%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL-----QGVPVVCM 82
           +A +LGSGLG     + NA  +SY ++P  P ++V GH+GEL+LG L     Q   + C 
Sbjct: 24  MAIVLGSGLGDFPKVLLNAKKLSYSQIPHMPQTSVQGHSGELILGELPTNDNQKRLIYCF 83

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM-- 140
            GR H YEG     +T  ++    +GC+L   TNA+G L  E+  G L  L  H   +  
Sbjct: 84  AGRIHSYEGGPWDEVTFQVKLMASIGCKLFIMTNASGGLFDEMSGGCLCLLTGHFRLLAR 143

Query: 141 -------PGTPMVG--LNDDRF--GERFFSLANAYD--------AEYRALLQKVAKEEGF 181
                  PG  +    L +  F   E+   + + Y         ++Y  L + VAKE+G 
Sbjct: 144 MDPNSLAPGARVSNGQLLETSFEKNEQISQIEDKYSHFAPDYWTSKYVNLCRSVAKEQGI 203

Query: 182 PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA 241
            L EG +    GP+FET  E+ M + +GG  VGMS VPE+++  +  ++ + +S + N+ 
Sbjct: 204 KLFEGSYAWASGPSFETPLEVLMAKQLGGACVGMSTVPEMLTCNYYGMECMGISMVCNLG 263

Query: 242 EGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
            GL    L+H + L  +++  ++   L+   L KI
Sbjct: 264 AGLQTEPLTHKEVLENSKIGTEHMQLLVKETLSKI 298


>UniRef50_Q1K0Y4 Inosine guanosine and xanthosine phosphorylase n=1
           Tax=Desulfuromonas acetoxidans DSM 684
           RepID=Q1K0Y4_DESAC
          Length = 274

 Score =  135 bits (340), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 81/232 (34%), Positives = 124/232 (53%), Gaps = 7/232 (3%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKL---PGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
             A ILGSG  + A+ +    ++ Y ++       ++ V GHAG+L +       ++  +
Sbjct: 22  ETAIILGSGWSSWAENLVIECSLDYSEVFRTQENSIANVPGHAGKLHVATWGECRLLVFQ 81

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           GR H Y+G     ++   +    +G + L  TNA G + PE+ AGS V +KDH+N     
Sbjct: 82  GRFHLYQGLTAAQVSQTAQLAHAMGTQRLVLTNAVGGIAPELMAGSFVIIKDHLNFQGDN 141

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIR 203
           P+ GL+   F      L N Y  ++   L+  A ++G  L  GV  +  GP++ET AEIR
Sbjct: 142 PLRGLSPSPF----IDLCNLYCTDFYPDLKIWADQQGIALHRGVLAAVVGPSYETPAEIR 197

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL 255
            ++ +G DVV MS+VPE I AR+  L+VV +S +TN A GLS   L H + L
Sbjct: 198 ALERLGADVVSMSMVPEAIMARYLGLEVVGLSLVTNPAAGLSTDPLQHQEVL 249


>UniRef50_B9KXK8 Purine nucleoside phosphorylase n=2 Tax=Thermomicrobia (class)
           RepID=B9KXK8_THERP
          Length = 289

 Score =  134 bits (337), Expect = 4e-30,   Method: Compositional matrix adjust.
 Identities = 91/259 (35%), Positives = 123/259 (47%), Gaps = 12/259 (4%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           TP    +LGSGL  L +       +  ++L       V GH  ELVL    G P+    G
Sbjct: 25  TPDALIVLGSGLATLPEDAHVVARVPLDELTAIAAPAVTGHPRELVLAEWNGHPIWFCLG 84

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHI------N 138
           R H Y+G         I     L   ++  TNAAGSL P    G LV ++DH        
Sbjct: 85  RYHLYQGLSAAEAAAPIALLAHLPGPIVILTNAAGSLHPTFAPGDLVLIRDHFFVPGLAG 144

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFET 198
             P  P  G        RFFSL +AYD   RA+ +  A   G  L EG +    GP FET
Sbjct: 145 HHPLIPPAGRV------RFFSLRDAYDRHLRAVARAAAARLGLELPEGTYAMVAGPTFET 198

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
           AAE+R ++  G D+VGMS +PEVI AR   L+V+A+S +TN+A        +H +  A  
Sbjct: 199 AAELRWLRAAGADLVGMSTIPEVILARALGLRVLAISVVTNLAIPEEPAIPTHEEVAAIG 258

Query: 259 ELSKQNFINLICGFLRKIA 277
           E ++     L+  FL ++A
Sbjct: 259 EQARPRLHRLLGFFLDQLA 277


>UniRef50_Q83H43 Purine nucleoside phosphorylase n=3 Tax=Tropheryma whipplei
           RepID=Q83H43_TROWT
          Length = 294

 Score =  134 bits (336), Expect = 5e-30,   Method: Compositional matrix adjust.
 Identities = 83/251 (33%), Positives = 131/251 (52%), Gaps = 13/251 (5%)

Query: 28  VAFILGSG-LGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQ-GVPVVCMKGR 85
           +A  LGSG + A+++  E    I  + + GF    + GH+G L    L  GV V+ +  R
Sbjct: 47  IAVTLGSGWVDAVSNLGELITTIPAQDIHGFFPPVLAGHSGVLTSIRLTCGVYVLVIGAR 106

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H Y+G G   +   I+T    G  +   TN AGS  P+ G G +V +KDHIN    +P+
Sbjct: 107 THLYQGHGPEAVVHGIKTAHAAGARVAILTNGAGSTVPDWGPGEVVVIKDHINLTGKSPL 166

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMM 205
            G N       F  +++ Y A  R  + ++A      + +GV+   PGP +ET AE++M+
Sbjct: 167 SGAN-------FCDMSDIYTAALRQKILQMAPN----IPQGVYAQMPGPQYETPAEVKML 215

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNF 265
           + IG D+VGMS   E I A+   + VV +S +TN+A G+   +LSH + L  +E ++Q  
Sbjct: 216 RTIGADLVGMSTALEAIMAKSLKMNVVGLSLVTNLAAGIGTGQLSHDEVLTVSEQARQKT 275

Query: 266 INLICGFLRKI 276
              +   +R I
Sbjct: 276 SAFLVELIRDI 286


>UniRef50_C4FCF5 Putative uncharacterized protein n=2 Tax=Collinsella
           RepID=C4FCF5_9ACTN
          Length = 295

 Score =  132 bits (333), Expect = 9e-30,   Method: Compositional matrix adjust.
 Identities = 88/243 (36%), Positives = 126/243 (51%), Gaps = 15/243 (6%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVST--VHGHAGELVLGHLQGVP 78
           KP     +A +LGSGLG+L +++     I Y  + GFP     V GH+  +++G L GVP
Sbjct: 37  KPTMEHPIAIVLGSGLGSLGERVRVVRHIPYSDIDGFPTEAIPVEGHSFTVLVGELDGVP 96

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCE--LLFC-TNAAGSLRPEVGAGSLVALKD 135
           VV   GR H Y+G     +T  +R    LGC   +L C T A G++ P    G++  + D
Sbjct: 97  VVVYPGRVHMYQGYDALQVTSLVRHAHKLGCRSIVLSCATGAVGAIAP----GTVGIITD 152

Query: 136 HINTMPGTPMV---GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
            IN     P+    G+        F S+A AY      L ++ A E G  L EGV+    
Sbjct: 153 QINLTGRNPLASPAGVAAAGLDSPFVSMAGAYSPYLSGLAREAASELGMELAEGVYAGLL 212

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP++ET AEIRM+  +G D VGMS V E I AR   ++V+ ++ +TN A    +   SHA
Sbjct: 213 GPSYETPAEIRMLGTLGADYVGMSTVCEAIMARAMGMEVLGIALVTNKAGCPGE---SHA 269

Query: 253 QTL 255
           + L
Sbjct: 270 KVL 272


>UniRef50_C7MEB8 Purine nucleotide phosphorylase n=2 Tax=Micrococcineae
           RepID=C7MEB8_BRAFD
          Length = 287

 Score =  131 bits (330), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 79/252 (31%), Positives = 126/252 (50%), Gaps = 14/252 (5%)

Query: 28  VAFILGSGLGALADQI-ENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGV--PVVCMKG 84
           +A +LGSG    AD + E         +PGF  + V GH G L    ++G     + +  
Sbjct: 30  LALVLGSGWSGAADLLGETVWQADATTIPGFRPAAVAGHVGTLRSIRVEGTGARALVLGA 89

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R HFYEG G+  +   +RT    G   +  TN  G + P    G+ V ++D IN    TP
Sbjct: 90  RTHFYEGAGVDAVVHGVRTAAATGARTMVLTNGCGGIDPAWAPGTPVLIRDQINFTGATP 149

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           +VG N       F  L + Y       L+++A++    L EGV++ + GP++ET AE++M
Sbjct: 150 LVGAN-------FVDLTDLYTPA----LREIARDVDATLDEGVYMQFSGPSYETPAEVQM 198

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
            + +G  +VGMS   E I+ R   + ++ +S +TN+A G+S   LSH + L A   +   
Sbjct: 199 AKAMGAHLVGMSTALEAIAVREAGMDLLGISLVTNLAAGISGDALSHEEVLEAGRAAGPR 258

Query: 265 FINLICGFLRKI 276
              L+   +R+I
Sbjct: 259 ISRLLAETVRRI 270


>UniRef50_A2FHY6 Inosine guanosine and xanthosine phosphorylase family protein n=1
           Tax=Trichomonas vaginalis RepID=A2FHY6_TRIVA
          Length = 780

 Score =  127 bits (318), Expect = 5e-28,   Method: Compositional matrix adjust.
 Identities = 84/255 (32%), Positives = 131/255 (51%), Gaps = 7/255 (2%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           TP V  +LGSGLG+   ++   + I Y+ +PG   +TV GH+G L+ G +  V V+C+ G
Sbjct: 24  TPEVGVVLGSGLGSYGQELAEPITIPYKNIPGMLDTTVPGHSGCLIFGKIGEVKVLCLSG 83

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN-TMPGT 143
           R H YEG     +  AIR     GC L+  TNAAG+    +  G L  + DH+N T  G 
Sbjct: 84  RSHQYEGLHPHEIQFAIRLLGGCGCRLVILTNAAGTCDELLEVGDLAPMLDHLNFTHRGY 143

Query: 144 PMVGLNDDRFGERFFSLANA-YDAEYRALLQKVAKEEGFPLTEGVFVSYP-GPNFETAAE 201
               L    F   +  + N  YD E + ++  VA E     T G   +Y  GP +E  AE
Sbjct: 144 TEEPLEIKDF---YHLIQNGMYDKEAQQVIHDVAVESNLS-TRGCNYTYNMGPTYEAHAE 199

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELS 261
           +   + +G    GMS V EVI+A+   + ++A+S +TN A G++   L+H +   AA+  
Sbjct: 200 VWGQKKLGCTNFGMSTVAEVIAAKEIGVPILAMSFVTNKAAGITGKLLTHVEVAEAAKKG 259

Query: 262 KQNFINLICGFLRKI 276
           ++    L+   + ++
Sbjct: 260 EEGMKKLVSTTIMRL 274


>UniRef50_B9CNR2 Purine nucleoside phosphorylase 1 n=2 Tax=Atopobium
           RepID=B9CNR2_9ACTN
          Length = 396

 Score =  127 bits (318), Expect = 5e-28,   Method: Compositional matrix adjust.
 Identities = 88/263 (33%), Positives = 127/263 (48%), Gaps = 11/263 (4%)

Query: 17  IKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVST--VHGHAGELVLGHL 74
           ++  KP     VA +LG+GLG LA+ ++    I Y  + GFPV    V GH+ E  +G +
Sbjct: 138 VEEIKPSVEHPVALVLGTGLGHLANLVKPVRRIDYRDIEGFPVDAQPVTGHSFEATIGTI 197

Query: 75  QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALK 134
            GVPVV   GR H Y+G     +T  ++    LGC  +    A G++    G G L  + 
Sbjct: 198 DGVPVVVYPGRVHLYQGYSAAEVTALVQHAHHLGCRDIIFAGATGAVPGNAGTG-LGIIT 256

Query: 135 DHIN---TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSY 191
           D IN   T P     GL +      F  + +AY    R L + VA + G  + EG+F   
Sbjct: 257 DQINLTGTNPLAEWAGLKN--VETPFVDMNDAYSPYLRTLARGVADDLGITVEEGIFAGL 314

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH 251
            GPNFET AE+ M++ +     G+S   EVI AR  ++ V+ ++   N A        +H
Sbjct: 315 LGPNFETPAEVNMLRAMNVSYTGVSTALEVIMARALNMNVLGLTLAANPAGARGT---TH 371

Query: 252 AQTLAAAELSKQNFINLICGFLR 274
              L AAE    +F  L+ G LR
Sbjct: 372 KSVLEAAEHYADDFERLVRGILR 394


>UniRef50_B3RV47 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
           RepID=B3RV47_TRIAD
          Length = 294

 Score =  126 bits (317), Expect = 6e-28,   Method: Compositional matrix adjust.
 Identities = 78/269 (28%), Positives = 133/269 (49%), Gaps = 13/269 (4%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAG-ELVLGHLQGVPV 79
           K   +P++  + G GL A+A+ I+    IS   LP FP       +  +L+ G + G PV
Sbjct: 24  KTRLSPKIGLVCGKGLDAVANIIQKKQVISCSSLPCFPSPNYKATSDHDLIFGLVSGKPV 83

Query: 80  VCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN- 138
           +C++G+ H YEG  +  +   I+    LG E+L     + SL P+   G +V +KDHIN 
Sbjct: 84  ICIQGQYHMYEGFSIETVILPIKIMFALGVEILLTIGVSRSLNPDFDIGDIVLVKDHINL 143

Query: 139 -TMPGTPMVGLNDDRFGERF----FSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSY 191
            ++ GT        +   +        +NAYD   R++++  A+  G    + +G  +  
Sbjct: 144 PSLCGTDSACYGTTKQTRQLNGTPIVKSNAYDVRLRSVVESSARTCGIGELIRQGTLMFV 203

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS---DVK 248
            GP+ E+ AE+R ++ +G D++ M  VPEV    HC++++ A+  IT    G     DV 
Sbjct: 204 SGPSLESNAELRFIRTLGMDMLAMDTVPEVTMGMHCNMRICALLIITYKDVGSEIGGDVS 263

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKIA 277
           + H Q L  A +   +  +L+C  +  I 
Sbjct: 264 MEH-QMLETARVRITDLQSLVCNVIGTIT 291


>UniRef50_UPI00016C3D31 inosine guanosine and xanthosine phosphorylase family protein n=2
           Tax=Gemmata obscuriglobus UQM 2246 RepID=UPI00016C3D31
          Length = 261

 Score =  125 bits (314), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 75/226 (33%), Positives = 113/226 (50%), Gaps = 6/226 (2%)

Query: 49  ISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLG 108
           + +  +PG    +VHGH G L +G   GVP + ++GR HFYEG    ++T  +RT   LG
Sbjct: 39  VPFGAVPGLVPPSVHGHGGTLAVGEWGGVPALLVRGRVHFYEGHPWEVVTGTVRTAAELG 98

Query: 109 CELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEY 168
              L  TNAAG + P +  G+L+A++ H+  +      GL       R       Y A  
Sbjct: 99  ARRLVLTNAAGGINPALSPGALMAIRGHLKLLGPAAWRGLAAGDGSVR------PYAARL 152

Query: 169 RALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCD 228
             +++   +  G  L  G++ +  GP++ET AEIR +   G D VGMS   E  +A    
Sbjct: 153 IEVMRAHERAGGRELLAGLYAALTGPSYETPAEIRALAACGADAVGMSTALEAEAAAARG 212

Query: 229 LKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLR 274
           L+V A+S +TN A G+    L HA+ L  A L+      L+   +R
Sbjct: 213 LEVAAISCVTNKAAGIGGTALDHAEVLTNAALAVDRLGALLGALIR 258


>UniRef50_D0JB48 Purine nucleoside phosphorylase n=2 Tax=Blattabacterium
           RepID=D0JB48_BLASB
          Length = 268

 Score =  124 bits (311), Expect = 4e-27,   Method: Compositional matrix adjust.
 Identities = 74/236 (31%), Positives = 126/236 (53%), Gaps = 26/236 (11%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           KPDF      +LGS    L ++I+N + ISYE++P F    ++G   + + G ++G  VV
Sbjct: 21  KPDFG---ILLLGSQFDKLIEEIQNPICISYEEIPLFSKKKLYG---KFLFGQIEGKNVV 74

Query: 81  CM------KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALK 134
            +      + R +++           I   K +G + L   N +G + P    G ++ +K
Sbjct: 75  FLIEPFSEENRTNYF----------TIVLCKHIGIDKLILINISGGVNPNYKMGDVMLVK 124

Query: 135 DHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGP 194
           DHIN  P +P +   +D    RFF +   YD +   + + +A      + +GV+V++P  
Sbjct: 125 DHINFFPESPNI---NDLIKNRFFEITEPYDQKMLEIAENIAMNHNIIIQKGVYVAFPYS 181

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
           N++T AE  M++ +GGD VGM++V +VI+AR  +L+V A+S I  M  GLS+ K+ 
Sbjct: 182 NYKTYAEYAMIRSMGGDSVGMNIVTDVITARCMNLRVFAISIIV-MGMGLSEPKIQ 236


>UniRef50_Q2S4Q1 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Salinibacter ruber DSM 13855 RepID=Q2S4Q1_SALRD
          Length = 285

 Score =  123 bits (308), Expect = 8e-27,   Method: Compositional matrix adjust.
 Identities = 69/190 (36%), Positives = 98/190 (51%), Gaps = 5/190 (2%)

Query: 49  ISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLG 108
           I Y  LP +P S      G L +G L G  VV +    H Y+G     ++  +R     G
Sbjct: 59  IPYANLPHYPASD-----GTLTIGTLGGTQVVELDQAFHLYDGHTPREVSFPVRMLATAG 113

Query: 109 CELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEY 168
            + L     AGS+  +   G L+ L DHIN     P+VG N + +G RF  +   YDA  
Sbjct: 114 IDSLLLAAPAGSVTAQADRGDLMLLTDHINFQGQNPLVGPNVEEWGPRFPDMTAPYDATL 173

Query: 169 RALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCD 228
           R      A+  G PL +G+++   GP+ ET AE RM   +G DVVG  VVPEV++ARH  
Sbjct: 174 RQRASDAARSAGVPLRQGIYMGLLGPHHETTAEHRMAHRLGADVVGTGVVPEVLAARHMG 233

Query: 229 LKVVAVSAIT 238
           + V+A++ +T
Sbjct: 234 VHVMALTLLT 243


>UniRef50_Q9RIJ1 Purine nucleoside phosphorylase homolog (Fragment) n=1
           Tax=Streptococcus pyogenes RepID=Q9RIJ1_STRPY
          Length = 149

 Score =  116 bits (290), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 61/147 (41%), Positives = 86/147 (58%), Gaps = 1/147 (0%)

Query: 127 AGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG 186
            G+L+A+ DHIN     P++G N D FG RF  +++AY   YR    +V  +    L +G
Sbjct: 2   TGTLMAITDHINMTGNRPLIGENLDEFGPRFPDMSDAYTKVYRDKAHEVHDKMNIKLEDG 61

Query: 187 VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD 246
           V++   GP +ET  EIR  Q +G D VGMS+VPEVI A H  LKV+ +SAITN A G   
Sbjct: 62  VYLGLTGPTYETPGEIRASQGLGEDPVGMSLVPEVIVAAHSGLKVLGISAITNFAAGFQS 121

Query: 247 VKLSHAQTLAAAELSKQNFINLICGFL 273
            +LSH + +   +  K++F  L+   L
Sbjct: 122 -ELSHEEVVEVTQHIKEDFTGLVKAIL 147


>UniRef50_C3ZRU9 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3ZRU9_BRAFL
          Length = 374

 Score =  115 bits (289), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 68/186 (36%), Positives = 109/186 (58%), Gaps = 11/186 (5%)

Query: 101 IRTFKLLGCELLFCTNAAGSLR-PEV-GAGSLVALKDHINTMPG----TPMVGLNDDRFG 154
           +R FKL+G         A  +  P V   G ++ +  HI +MPG     P+ G N+DRFG
Sbjct: 190 VRVFKLMGILSAPLPQVALPVALPAVFNDGYIMLMTPHI-SMPGLAGDNPLKGHNEDRFG 248

Query: 155 ERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNFETAAEIRMMQIIGGDV 212
            RF ++++AY++E R + + + KE GF   + EGV+V   GP++ET AE ++++++GGD 
Sbjct: 249 PRFPAVSDAYNSELRQMARDIGKELGFESFMQEGVYVQVGGPSYETIAECKLLRMLGGDA 308

Query: 213 VGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK--LSHAQTLAAAELSKQNFINLIC 270
           VGMS VPEVI+ARHC ++V  +S +TNM     D K  ++H + L       Q+   L+ 
Sbjct: 309 VGMSTVPEVIAARHCGIRVFGMSLVTNMVVMDYDTKGTVNHEEVLETGRRRAQDMQKLVS 368

Query: 271 GFLRKI 276
             + ++
Sbjct: 369 KMIGQL 374



 Score = 51.2 bits (121), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 36/96 (37%), Positives = 48/96 (50%), Gaps = 4/96 (4%)

Query: 15  DIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL 74
           D I T K    P++A I GSGLG LAD +E+  AI Y ++P FP ST  G+     L  +
Sbjct: 16  DFILT-KTKHRPKIAVICGSGLGGLADIVEDQNAIDYSEIPNFPRSTADGYTQSAPLPQV 74

Query: 75  QGVPVVCMKGRGHFYEGRGMTIMTDA--IRTFKLLG 108
             +PV   K  G          +  A  +R FKL+G
Sbjct: 75  -ALPVRVFKLMGILSAPLPQVALPVALPVRVFKLMG 109


>UniRef50_A8B9X8 Purine nucleoside phosphorylase lateral transfer candidate n=3
           Tax=Giardia intestinalis RepID=A8B9X8_GIALA
          Length = 805

 Score =  115 bits (288), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 77/270 (28%), Positives = 127/270 (47%), Gaps = 44/270 (16%)

Query: 28  VAFILGSGLGALADQIENA--VAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           +A +LGSGL   AD++ +     I YE++P    ++V GH+G++++G +    ++C  GR
Sbjct: 49  IAVVLGSGLSGFADRMFSTGYTEIDYERVPFMAKTSVSGHSGKVLVGEMGDKTILCFSGR 108

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H YEG     +T        LG  +   TNAAG  +  + AG L+ + D ++ +   P+
Sbjct: 109 FHSYEGYTPPTLTIFPYVACYLGARIYIVTNAAGGTKRGMEAGCLMLINDQMSLLRWNPL 168

Query: 146 VGLNDDRFG---------ERFFSL------------------ANAYDAEYRALLQKVAKE 178
            G    +           E   +L                  AN Y AE R+L++++AK+
Sbjct: 169 YGYESCQLQHDPDCLLELENLKALLGYLKTPGLFHYPSSIPNANIYSAELRSLVRELAKD 228

Query: 179 EGF---------------PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVIS 223
           + F                + EG +V   GP++ET  +   +  +G   VGMS +PE + 
Sbjct: 229 KAFIDKTSIMLKGHKHMVKVYEGTYVLNSGPHYETQIDTETIMSLGPGAVGMSSIPEALC 288

Query: 224 ARHCDLKVVAVSAITNMAEGLSDVKLSHAQ 253
           AR   + V+ +S +TN+A GLS   L HA 
Sbjct: 289 ARLLGMHVIGLSVVTNLAAGLSKETLDHAD 318


>UniRef50_Q9W1K6 CG18128 n=7 Tax=melanogaster group RepID=Q9W1K6_DROME
          Length = 339

 Score =  114 bits (285), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 74/221 (33%), Positives = 108/221 (48%), Gaps = 7/221 (3%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P+   I GS L  +   +E  V I YE +P FP       +   VLG + G P++ +   
Sbjct: 65  PKYGLICGSFLSDMVSLVEQPVVIPYEDIPNFPDGIEPDCS--FVLGTVMGAPIIALVHS 122

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINT---MPG 142
            H  +G  +      +R  +L G   +  T+ A ++      G ++ ++DHIN    M  
Sbjct: 123 FHSCDGYNLATCALPVRVMQLCGVRTIMLTSEAAAVDHGFALGDIMLVQDHINVVGMMHQ 182

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNFETAA 200
           TP+ G +D RFG R FS+ NAYD +      ++ K  G    L  GV     GP   T A
Sbjct: 183 TPLEGPSDPRFGSRRFSMVNAYDKDLLEKALEIGKRMGIQKFLHSGVLACMGGPILGTVA 242

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA 241
           E RM++ +    VGMS+VPEVI+A H  LKV+A   I+  A
Sbjct: 243 EERMLRTMEVSAVGMSLVPEVIAAHHGGLKVLAFVVISRAA 283


>UniRef50_Q5C0P1 SJCHGC05230 protein (Fragment) n=1 Tax=Schistosoma japonicum
           RepID=Q5C0P1_SCHJA
          Length = 186

 Score =  109 bits (272), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 60/140 (42%), Positives = 80/140 (57%), Gaps = 5/140 (3%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
            P V  I GSGLG LAD I++   I Y+ +P FP +++ GH+G LV G + G  V+ M+G
Sbjct: 48  VPEVGIICGSGLGKLADGIKDKKIIPYKDIPNFPQTSIPGHSGNLVFGTISGRNVIVMQG 107

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG-- 142
           R H YEG     +   IR  K+LG ++L  +NAAG L   +  G  V LKDHI   PG  
Sbjct: 108 RFHMYEGYNKDEIALPIRVMKILGVKILMVSNAAGGLNRSLKCGDFVILKDHI-YFPGLG 166

Query: 143 --TPMVGLNDDRFGERFFSL 160
               +VG N + FG RF +L
Sbjct: 167 LNNILVGPNQEEFGPRFPAL 186


>UniRef50_Q0CL04 Purine nucleoside phosphorylase n=1 Tax=Aspergillus terreus NIH2624
           RepID=Q0CL04_ASPTN
          Length = 205

 Score =  107 bits (268), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 74/182 (40%), Positives = 97/182 (53%), Gaps = 18/182 (9%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYE--KLPGFPVSTVHGHAGELVLGHL-QGVPVVC 81
           +PRVA + GSGLG LAD I +     Y+   +P FP  TV GHAG+LV G L + +PVV 
Sbjct: 31  SPRVAIVCGSGLGGLADSIRDHPRAEYDYGSIPHFPKLTVPGHAGKLVFGFLGEDIPVVL 90

Query: 82  MKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHI--NT 139
           M GR H+YEG  +  +T  IR FKLLG E +      GS+           +  HI  + 
Sbjct: 91  MVGRAHYYEGHSIHQVTFPIRVFKLLGVETVVFYR--GSM-----TKWFTDIAKHIFLSG 143

Query: 140 MPGT-PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-----EGVFVSYPG 193
           + G  P+ G ND+ FG RF  L++AYD E R  + K  K    PL+     EGV+    G
Sbjct: 144 LAGNHPLRGPNDEEFGPRFPPLSDAYDLELRRHVHKAWKTVVDPLSKRRLHEGVYAYVGG 203

Query: 194 PN 195
           P 
Sbjct: 204 PR 205


>UniRef50_A2VPA1 Purine nucleoside phosphorylase deoD n=1 Tax=Mycobacterium
           tuberculosis C RepID=A2VPA1_MYCTU
          Length = 241

 Score =  104 bits (259), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 67/180 (37%), Positives = 96/180 (53%), Gaps = 13/180 (7%)

Query: 92  RGMTIMTDAIRTFKLL--GCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLN 149
           R  T  T  IR  + +  G  L         LR ++  G  V + DH+N    +P+VG  
Sbjct: 66  RDTTCATSCIRFGRPVRQGRRLWCSPTPPVGLRADLQVGQPVLISDHLNLTARSPLVG-- 123

Query: 150 DDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIG 209
               GE F  L +AY       L+++A++    L EGV+   PGP++ET AEIRM+Q +G
Sbjct: 124 ----GE-FVDLTDAYSPR----LRELARQSDPQLAEGVYAGLPGPHYETPAEIRMLQTLG 174

Query: 210 GDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLI 269
            D+VGMS V E I+AR    +V+ VS +TN+A G++   LSHA+ LAA   S      L+
Sbjct: 175 ADLVGMSTVHETIAARAAGAEVLGVSLVTNLAAGITGEPLSHAEVLAAGAASATRMGALL 234


>UniRef50_C1YKP8 Inosine guanosine and xanthosine phosphorylase family protein n=1
           Tax=Nocardiopsis dassonvillei subsp. dassonvillei DSM
           43111 RepID=C1YKP8_NOCDA
          Length = 274

 Score = 94.7 bits (234), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 60/188 (31%), Positives = 92/188 (48%), Gaps = 12/188 (6%)

Query: 31  ILGSGLGALADQIEN-AVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFY 89
           +LGSG     D + +  + +    LPGF      GH+G++    +    V+   GR H Y
Sbjct: 39  VLGSGWAGAVDTLGSYDIELDATDLPGFHEPAAEGHSGKIRSMWVGDKRVIVFMGRVHLY 98

Query: 90  EGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLN 149
           EGR    +  A+RT    G      T AAGSLR +   G  V ++DHIN    +P+VG +
Sbjct: 99  EGRDPLEVVHAVRTGVAAGARTAVLTGAAGSLRTDFATGQPVVVRDHINLTARSPLVGPS 158

Query: 150 DDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIG 209
                  F  L++AY       L++  +E    + EGV+V   GP  +T AE++++   G
Sbjct: 159 -------FVDLSSAYSPR----LRRAVQEADASVPEGVYVCTTGPQTQTPAELKVLHQAG 207

Query: 210 GDVVGMSV 217
            D+VG S+
Sbjct: 208 ADLVGHSI 215


>UniRef50_UPI0001926077 PREDICTED: similar to nucleoside phosphorylase, partial n=1
           Tax=Hydra magnipapillata RepID=UPI0001926077
          Length = 117

 Score = 94.4 bits (233), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 46/92 (50%), Positives = 58/92 (63%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           K    P +  I GSGLG L + IEN    SYE +PGFPVSTV GHAG+LV G ++   +V
Sbjct: 23  KTQLRPTIGVICGSGLGGLVNNIENKEEFSYEDIPGFPVSTVKGHAGKLVFGTIKEKILV 82

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELL 112
           C++GR HFYEG G+   T  +R   LLG + L
Sbjct: 83  CLQGRFHFYEGHGINKCTLPVRVMALLGIKTL 114


>UniRef50_A6GFX4 Purine nucleoside phosphorylase n=1 Tax=Plesiocystis pacifica SIR-1
           RepID=A6GFX4_9DELT
          Length = 278

 Score = 91.7 bits (226), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 81/273 (29%), Positives = 127/273 (46%), Gaps = 26/273 (9%)

Query: 13  CIDIIKTYKPDFTPRVAFILG-SGLGA-LADQIENAVAIS-YEKLP----GFPVSTVHGH 65
           C   ++   P+  P    I+G SG+G  L  + E+A+ +S  E++P    G P  +V GH
Sbjct: 14  CEAALRERLPEQGPVDWMIIGGSGIGKPLVAEGEHALGLSIRERIPLAELGLPAPSVAGH 73

Query: 66  AGELVLGHL--QGV-PV-VCMK-GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
             ELV G L  +G  PV VC++ GR H YEG    + +  +     +G   +  T+A G 
Sbjct: 74  GSELVFGELAREGADPVQVCVQTGRIHPYEGHSAALASAPLGAVLSIGARQVLLTSAVGG 133

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           +  ++  G +V+ +D  N    T +        G  F   +  YD E RA LQ++     
Sbjct: 134 VNTQLRVGEIVSYRDQFNLFGPTSL-------RGAAFIDCSRLYDPELRARLQQLDGS-- 184

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
             L E V+    GP +E+ AE+  ++ +G DVVGMS   E I A    +    +  +TN 
Sbjct: 185 --LREVVYGHARGPQYESPAEVAALRTLGCDVVGMSTTYEAILAAAHGVPTCGLGVVTNA 242

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFL 273
           A       LSH +    +  ++    NL+ G L
Sbjct: 243 A---GAEALSHVEVQEESGKARTRLANLVRGLL 272


>UniRef50_A7BDZ0 Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus
           ATCC 17982 RepID=A7BDZ0_9ACTO
          Length = 265

 Score = 88.6 bits (218), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 69/243 (28%), Positives = 107/243 (44%), Gaps = 18/243 (7%)

Query: 26  PRVAFILGSGLGALADQIENAVA--ISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
           P     LGSGL    D+   A A  +S   +PG       GH GEL      G  V+   
Sbjct: 30  PDALVALGSGLSEALDEAWGAPAATVSLGDIPGVVAPVADGHGGELRAYEACGGVVLVAT 89

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           GR H YEG G+  +    R     G      TNA G L+P    G ++A+ DH+N    +
Sbjct: 90  GRTHLYEGLGVRPVAALARAAVAAGISRAVLTNANGCLKPW-NLGDVMAITDHVNLSGAS 148

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIR 203
           P         G  F  ++  +DA+    L+ V +       EG +    GP ++T AE R
Sbjct: 149 PF-------DGPLFLDVSAVWDAQMTQALRGVCQR------EGTYAILRGPEYQTMAETR 195

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
           ++  +G D VGMS V E I+     ++V  +S +++++   +D        + AA  ++Q
Sbjct: 196 ILSGLGVDCVGMSTVMEAITLHALGVRVAGMSVVSDLS--FADGPTDPTAVVEAASAARQ 253

Query: 264 NFI 266
             +
Sbjct: 254 TVV 256


>UniRef50_UPI0000D5796F PREDICTED: similar to purine nucleoside phosphorylase, partial n=1
           Tax=Tribolium castaneum RepID=UPI0000D5796F
          Length = 153

 Score = 88.2 bits (217), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 52/130 (40%), Positives = 80/130 (61%), Gaps = 12/130 (9%)

Query: 153 FGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNFETAAEIRMMQIIGG 210
           FG RF  +  AY+ E     +KVA+E G    + EG +    GPNFET AE+RM++++G 
Sbjct: 20  FGPRFPPMNKAYNRELIDQGKKVARELGMGGMVHEGTYTCLGGPNFETVAELRMLKMLGA 79

Query: 211 DVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDV----KLSHAQTLAAAELSKQNFI 266
           D VGMS V EVI+ARHCD+ V+A S ITN+   ++D     K +H + +   ++ +Q+ +
Sbjct: 80  DAVGMSTVHEVITARHCDMTVLAFSLITNIC--ITDYECHDKPNHEEVMDVGKM-RQDTL 136

Query: 267 NLICGFLRKI 276
            L   F++K+
Sbjct: 137 KL---FVKKL 143


>UniRef50_B5Y8G4 Methylthioadenosine phosphorylase n=1 Tax=Coprothermobacter
           proteolyticus DSM 5265 RepID=B5Y8G4_COPPD
          Length = 249

 Score = 85.5 bits (210), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 52/156 (33%), Positives = 85/156 (54%), Gaps = 6/156 (3%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSL 160
           IR  + LG + +  TNA GSL PE+  G++V +   ++   G       + +       +
Sbjct: 66  IRALQGLGAQRIIATNAVGSLNPEIKPGTVVLVDQFLDFTKGRKSTFFEEGKVVHT--DM 123

Query: 161 ANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVP 219
            N Y  E   +  K+     FPL +G V V   GP FETAAE++   ++GGDVVGM+ VP
Sbjct: 124 TNPYCPEMIEVASKITTP--FPLRKGGVMVVTEGPRFETAAEVKAFAMLGGDVVGMTSVP 181

Query: 220 EVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL 255
           EV+ +R   +  ++++ ++N A GL + ++SH + L
Sbjct: 182 EVVLSREAGMCYLSLAIVSNFAAGLQE-QVSHEEVL 216


>UniRef50_B0K2V3 Purine phosphorylase, family 2 n=10 Tax=Thermoanaerobacteraceae
           RepID=B0K2V3_THEPX
          Length = 256

 Score = 85.5 bits (210), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 54/168 (32%), Positives = 82/168 (48%), Gaps = 2/168 (1%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSL 160
           I   K +G + ++ T A GS       G +V LKD ++     P+     +    R   +
Sbjct: 65  IMALKQMGVKYVYATAAVGSFNENYEPGDVVVLKDFLDFTKSRPLTFFEGEDGVVRHVDM 124

Query: 161 ANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVP 219
           ++ Y +  RA     AK+E   +  + V+V   GP FETA EIRM + +G DVVGM+ VP
Sbjct: 125 SDPYCSNLRAKFYNAAKKEDLLIKGDAVYVCTEGPRFETAQEIRMYKNLGADVVGMTNVP 184

Query: 220 EVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFIN 267
           EVI A+   +   AV  ++N A G+      H +     EL+K+  I 
Sbjct: 185 EVILAKELGMCYAAVGIVSNWATGMKGSITLH-EIKDTLELNKEKVIK 231


>UniRef50_C2KQL7 Possible purine-nucleoside phosphorylase n=2 Tax=Mobiluncus
           mulieris RepID=C2KQL7_9ACTO
          Length = 279

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 66/235 (28%), Positives = 112/235 (47%), Gaps = 21/235 (8%)

Query: 28  VAFILGSGL-GALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQG----VPVVCM 82
           V  +LGSGL   + +  +N V +  ++L G  + +  GH  ++V   ++     V ++  
Sbjct: 41  VLVVLGSGLHDTVCNLGKNPVELPLKELLGAKIPSAQGHGTQIVSVQIETEAKTVNILVC 100

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            GR H YEG     +    +   + G +  F TNA G L+P    G ++A++DHIN    
Sbjct: 101 TGRIHLYEGHTPADLCFVPQVAAMTGIQAAFLTNAGGCLQPW-ELGDVMAIRDHINFSGA 159

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEI 202
           +P  G         F  ++  +D++  A ++K A   G      V+    GP ++T AE 
Sbjct: 160 SPFTG-------PVFVDISQVWDSDLTAAIKKHASRSG------VYAISRGPEYQTLAES 206

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAA 257
            MM+  G D+VGMS V E I+     ++V  VS  +++    S    +H++ L A
Sbjct: 207 IMMRNNGIDMVGMSTVLEAIALHQLGVRVCGVSVTSDLT--FSSTPTTHSEVLHA 259


>UniRef50_Q465I0 Methylthioadenosine phosphorylase n=4 Tax=Methanosarcinaceae
           RepID=Q465I0_METBF
          Length = 258

 Score = 83.6 bits (205), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 56/170 (32%), Positives = 84/170 (49%), Gaps = 5/170 (2%)

Query: 107 LGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDA 166
           +G + +  TN+ GS+R     GS V L D I+     P     DDR       ++  Y  
Sbjct: 77  IGAKRVISTNSVGSMRGH-PVGSFVVLDDFIDFTRNRPST-FYDDRTAH--VDVSEPYCP 132

Query: 167 EYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARH 226
           E R  L+   +++G P TEG++    GP FET AEIRMM     DVVGM+ VPEV  A+ 
Sbjct: 133 EIRIALRDALEKQGLPYTEGIYACTEGPRFETRAEIRMMSQF-ADVVGMTGVPEVGLAKE 191

Query: 227 CDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
             L   +++ +TN A G++  KL+  +       ++     +I   + KI
Sbjct: 192 LSLCYASLAIVTNQACGMTTQKLTADEVTEVVGKAQDAIFEIISDTIEKI 241


>UniRef50_C0QPX3 Methylthioadenosine phosphorylase n=6 Tax=Aquificales
           RepID=C0QPX3_PERMH
          Length = 280

 Score = 81.3 bits (199), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 57/241 (23%), Positives = 108/241 (44%), Gaps = 24/241 (9%)

Query: 59  VSTVHGHAGE-LVLGHLQGVPVVCM--KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCT 115
           +ST +G   +  ++   +G   V +   G+GH Y    +    + I  F+ LG + +   
Sbjct: 24  ISTPYGEPSDRYIIAEYRGKKAVFLPRHGKGHKYPPHLINYRAN-IWGFRKLGVDRILSV 82

Query: 116 NAAGSLRPEVGAGSLV---ALKDHINTMPGTPMVGL---------NDDRFGERF------ 157
           +A G + P +  G  V      D     P T   G+          DD   E        
Sbjct: 83  SAVGGINPLLKPGDFVLSDQFIDFTKVRPVTFYEGVYTIYDETDGKDDLVSEYLKNNRVV 142

Query: 158 -FSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGM 215
              + + + +  R  L  +  E+G+    +G +++  GP  ET+AEI+   I+G D+VGM
Sbjct: 143 HIDVTDPFCSSMRKTLSDILDEKGYRYHKKGTYIATEGPRLETSAEIKAFSILGADIVGM 202

Query: 216 SVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRK 275
           ++VPE++ AR   +   +++ +TN+A G+S  +L+  + +   +        +I  F+ K
Sbjct: 203 TLVPEIVLARELSMHFASINVVTNLAAGISGERLTSDEVIQMMKEKNDQIKEIILSFIEK 262

Query: 276 I 276
           +
Sbjct: 263 V 263


>UniRef50_O27633 Methylthioadenosine phosphorylase n=7 Tax=Archaea
           RepID=O27633_METTH
          Length = 280

 Score = 79.7 bits (195), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 51/176 (28%), Positives = 82/176 (46%), Gaps = 7/176 (3%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSL 160
           I   K LG   +  TNA GSL+  +G G  V   D ++     P    ++         +
Sbjct: 68  IWALKELGVRQIIATNAVGSLKRSIGPGDFVVPHDFLDFTRSRPSTFYDEKTV---HVDM 124

Query: 161 ANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPE 220
              Y    R+ L   +      +  GV+V   GP FET AEIRM Q +GG VVGM+ +PE
Sbjct: 125 TEPYCRNIRSALSGSSGV----VDGGVYVCTEGPRFETPAEIRMFQTLGGTVVGMTGLPE 180

Query: 221 VISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
            + AR  ++   ++  ++N A  +S  KL+  +     +  K + I++I   +R +
Sbjct: 181 AVLARELEMCYASICLVSNYAASISPSKLTIDEVFEIMDEKKNDLIDIIDAAIRDL 236


>UniRef50_UPI0000E4A236 PREDICTED: similar to GTP-binding protein, partial n=3
           Tax=Strongylocentrotus purpuratus RepID=UPI0000E4A236
          Length = 690

 Score = 79.3 bits (194), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 46/122 (37%), Positives = 73/122 (59%), Gaps = 6/122 (4%)

Query: 160 LANAYDAEYRALLQKVAKEEGF-PLT-EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSV 217
           +   YD + R    KVA+E+   P T +GV++   GP++ET AE R ++ +GGDVVGMS 
Sbjct: 1   MNKVYDEKLRNSALKVAEEQRIAPFTRQGVYLMVGGPSYETPAEARYLRALGGDVVGMST 60

Query: 218 VPEVISARHCDLKVVAVSAITN---MAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLR 274
           VPEV++ARHC ++ + +S IT+   M  G +   ++H   L  A+      I+L+ G + 
Sbjct: 61  VPEVLAARHCGMRALGLSLITDIVTMDYGAAGA-INHDDFLETAKWRAATMIDLVVGVVE 119

Query: 275 KI 276
           K+
Sbjct: 120 KM 121


>UniRef50_B9K7V5 Purine nucleoside phosphorylase n=1 Tax=Thermotoga neapolitana DSM
           4359 RepID=B9K7V5_THENN
          Length = 148

 Score = 77.8 bits (190), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 41/111 (36%), Positives = 60/111 (54%), Gaps = 7/111 (6%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           +P +  +LGSG  +  + ++N   I Y+ +P FP  TV GH+G+LV G ++  PV+ M G
Sbjct: 23  SPEILIVLGSGFSSFVEAMDNCTTIDYKDIPHFPQPTVEGHSGKLVFGIVKDRPVMVMAG 82

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAG-------SLRPEVGAG 128
           R H YEG     +   I   K LG + +  TNAAG       + R + GAG
Sbjct: 83  RFHLYEGHAPQRVAFPIYVAKFLGVKGVIVTNAAGGDKSGVQTRRSDSGAG 133


>UniRef50_Q0W2D2 Putative purine phosphorylase (Family 2) n=1 Tax=uncultured
           methanogenic archaeon RC-I RepID=Q0W2D2_UNCMA
          Length = 258

 Score = 77.8 bits (190), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 68/234 (29%), Positives = 103/234 (44%), Gaps = 14/234 (5%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM--K 83
           PR A I GSG   +         +  +K+    V T +G A      + +G   V +   
Sbjct: 2   PRTAIIGGSGFYCVP-----GCNLKEKKV----VRTKYGDATLFFYENEKGAEFVFLPRH 52

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           G GH      +    + I   K  G E +   ++ GSLR  +  G  V L   ++     
Sbjct: 53  GEGHTCAPHRINYRANVI-ALKEAGIERIIGISSVGSLREAIRPGDFVLLDQFLDFTKAR 111

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIR 203
           P+   ++D        +   Y  + R  +    + +     +G +V   GP FETAAEIR
Sbjct: 112 PITFFDEDGC-VVHTDMTEPYCHDLRQCILSAPRGDIRLHDKGTYVCTEGPRFETAAEIR 170

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAA 257
           M   +GGDVVGM+ VPEV+ AR   +    +S  TN A G+S V ++H + L A
Sbjct: 171 MYATLGGDVVGMTGVPEVVLARELGMCYAGISVATNYAAGISKV-VTHEEVLEA 223


>UniRef50_Q1NY44 Methylthioadenosine phosphorylase n=2 Tax=delta proteobacterium
           MLMS-1 RepID=Q1NY44_9DELT
          Length = 251

 Score = 74.7 bits (182), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 69/230 (30%), Positives = 96/230 (41%), Gaps = 25/230 (10%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH-AGELVLGHLQGVPVVCMKGRG 86
           +A I GSGL       +N      E+   F V T +G  +  L+ G L G  VV +    
Sbjct: 4   IAIIGGSGL-------DNPEFFDVEQ--EFTVETPYGPPSAPLLQGRLDGREVVLLA--- 51

Query: 87  HFYEGRGMTIMTDAIRT------FKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
               GR  TI    +         +  GCE +  T A+GSLR E+G G LV     I+  
Sbjct: 52  --RHGRQHTIPPSRVNNRANLFALREAGCERIIATAASGSLRNEIGPGHLVIPDQFIDFT 109

Query: 141 PGTPMVGLNDDRFGER---FFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNF 196
              P+   ++   G        LA+ +D   R  +     E   PL T G  ++  GP F
Sbjct: 110 RQRPLTFYDEFPAGIENACHTPLADPFDETLRQKIIAAGGERQIPLHTSGTILTIEGPRF 169

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD 246
            T AE RM Q  G D+V M+V PE I A    L    ++ +T+      D
Sbjct: 170 STRAESRMYQSWGADLVNMTVAPEAILAAELKLPYAVIAMVTDYDSWKED 219


>UniRef50_O57865 Uncharacterized protein PH0125 n=36 Tax=Archaea RepID=Y125_PYRHO
          Length = 257

 Score = 74.7 bits (182), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 61/216 (28%), Positives = 96/216 (44%), Gaps = 15/216 (6%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P++  I GSG+  + +  E     +    P  P+           +G ++GV V  +   
Sbjct: 2   PKIGIIGGSGVYGVFEPKEVVKVHTPYGRPSAPIE----------IGEIEGVEVAFIPRH 51

Query: 86  GHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           G ++E     +   A I     LG E +   NA GSL+ E   G +V +   I+      
Sbjct: 52  GKYHEFPPHQVPYRANIWALHELGVERVIAINAVGSLKEEYKPGDIVIIDQFIDFTKKRE 111

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIR 203
               N  +      S+A+ +  E R +  + AKE   P+ E G +V   GP F T AE R
Sbjct: 112 YTFYNGPKVAH--VSMADPFCPELRKIFIETAKELNLPVHERGTYVCIEGPRFSTRAESR 169

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
           M +    DV+GM++VPEV  AR   +  V +S +T+
Sbjct: 170 MFRQFA-DVIGMTLVPEVNLARELGMCYVNISTVTD 204


>UniRef50_C0W9U9 Purine nucleoside phosphorylase n=1 Tax=Acidaminococcus sp. D21
           RepID=C0W9U9_9FIRM
          Length = 268

 Score = 73.9 bits (180), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 35/90 (38%), Positives = 54/90 (60%)

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           G +V+  GP +ETAAE+RM  ++GGDV GM+ +PE + AR  ++     S +TNM  GLS
Sbjct: 154 GCYVATEGPRYETAAEVRMYGLMGGDVAGMTQMPEAVLAREAEICYANCSLVTNMGSGLS 213

Query: 246 DVKLSHAQTLAAAELSKQNFINLICGFLRK 275
              LSH + +A  + + +    +I  FL +
Sbjct: 214 WTALSHEEVVAMMDENAKTIARIIHAFLTE 243


>UniRef50_Q60367 Uncharacterized protein MJ0060 n=11 Tax=Methanococcales
           RepID=Y060_METJA
          Length = 252

 Score = 73.2 bits (178), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 49/173 (28%), Positives = 81/173 (46%), Gaps = 3/173 (1%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSL 160
           I   K LG E +   N+ GSL+ ++  G      D I           ++ +       +
Sbjct: 62  IYALKKLGVERILAINSVGSLKEDLKPGMFFVPNDFIEFTKKREETFYDEGKVVH--IDM 119

Query: 161 ANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPE 220
            + Y  E R +L+ +  +  F   EGV+V   GP FET  EI + +   GDVVGM+  PE
Sbjct: 120 TDPYCPELRNILKSILDKNNFSYGEGVYVCTEGPRFETKKEIAIYKN-WGDVVGMTGYPE 178

Query: 221 VISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFL 273
           V+ AR  ++  V++  ITN A G+S   L+  + L   +  +   + ++  F+
Sbjct: 179 VVLARELEMCYVSLCNITNYACGISKNILTVDEVLEKIKEMENKILKVVEDFI 231


>UniRef50_A3TNF6 Methylthioadenosine phosphorylase n=1 Tax=Janibacter sp. HTCC2649
           RepID=A3TNF6_9MICO
          Length = 272

 Score = 72.0 bits (175), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 56/176 (31%), Positives = 81/176 (46%), Gaps = 3/176 (1%)

Query: 72  GHLQGVPVVCMKGRGHFYEGRGMTIMTDAI-RTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
           G   G PVV +   G  +E     +   AI R    LG   +   N  G + P++ AG +
Sbjct: 43  GSWHGQPVVFVTRHGAGHEVPPHMVNYRAIVRALADLGVHDVIAVNVTGGIDPDLEAGEI 102

Query: 131 VALKDHIN-TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VF 188
           V + D ++ T   +      D   G     +  AYD   R  L   A   G  + +G V+
Sbjct: 103 VVIDDFLDFTRQRSATFHDGDGPEGVVHTDMTTAYDPVLRRELLDAASAIGQSVIDGGVY 162

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL 244
           V + GP FE+ AEIR+  + GG V GM+ VPEV  A    L+  A+S + N A G+
Sbjct: 163 VCFDGPRFESPAEIRLAALAGGTVAGMTGVPEVTLAAEAGLRYAALSLVVNPAAGV 218


>UniRef50_D2RKT9 Purine or other phosphorylase family 1 n=1 Tax=Acidaminococcus
           fermentans DSM 20731 RepID=D2RKT9_ACIFE
          Length = 275

 Score = 71.2 bits (173), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 49/174 (28%), Positives = 77/174 (44%), Gaps = 1/174 (0%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSL 160
           I   K LG   +    A GSL   +  G+ V     ++          N +         
Sbjct: 68  IFALKKLGVTEILSFTAVGSLNRGLPPGTFVVTSQLLDFTKSRVNTFFNGENGQVAHVDF 127

Query: 161 ANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVP 219
           A  Y    R  L +   + G   + +G +V   GP +ETAAE+RM   +GGDV GM+ +P
Sbjct: 128 AQPYCPALRERLNRCLVKLGLRHSKQGTYVVTEGPRYETAAEVRMYAAMGGDVAGMTNMP 187

Query: 220 EVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFL 273
           E + AR  ++     S +TNM  GL+   LSH +   A E  ++  + +I  ++
Sbjct: 188 EAVLAREAEICYANCSVVTNMGSGLAVRSLSHEEVTEAMERLEKQILAVIEAYV 241


>UniRef50_Q87ZC3 Probable S-methyl-5'-thioadenosine phosphorylase n=45 Tax=cellular
           organisms RepID=MTNP_PSESM
          Length = 246

 Score = 68.9 bits (167), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 54/200 (27%), Positives = 86/200 (43%), Gaps = 3/200 (1%)

Query: 57  FPVSTVHGH-AGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDA-IRTFKLLGCELLFC 114
            P++T +G  +GE+ +G   G  V+ +   GH +      +   A I   K  G E +  
Sbjct: 24  LPMNTPYGAPSGEIQIGDYAGREVMFLARHGHPHRLPPHQVNYRANIWALKQAGAEAILA 83

Query: 115 TNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQK 174
            NA G + P +G G      D ++   G       DD         +  Y    R  L  
Sbjct: 84  VNAVGGIHPAMGTGHFCVPHDLVDYTSGRQHTFFADDLEEVTHIDFSYPYSEALRVRLVA 143

Query: 175 VAKEEGFPLTE-GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVA 233
               EG   ++ GV+    GP  ET AEI  ++  G D+VGM+ +PE   AR  +L+   
Sbjct: 144 ALAAEGCAFSDRGVYACTQGPRLETVAEIIRLERDGCDIVGMTGMPEAALARELELEYAC 203

Query: 234 VSAITNMAEGLSDVKLSHAQ 253
           ++ + N A G S   ++ A+
Sbjct: 204 LALVVNPAAGKSTAVITMAE 223


>UniRef50_Q18KQ3 5'-methylthioadenosine phosphorylase MtaP n=4 Tax=Halobacteriaceae
           RepID=Q18KQ3_HALWD
          Length = 301

 Score = 67.8 bits (164), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 72/267 (26%), Positives = 114/267 (42%), Gaps = 39/267 (14%)

Query: 28  VAFILGSGL-GALADQIENAVAISYEKLPGFPVSTVH-GHAGELVLGHLQGVPVVCMKGR 85
           + FI GSG+  AL   ++N   I  E   G P + +  G  GE       G  V+ +   
Sbjct: 6   IGFIGGSGIYEALG--LQNTHTIEIETPFGEPAAPLTVGEVGET------GREVIFLPRH 57

Query: 86  GHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           G  +E    T+   A I   K  G   +  +NA GSLR E+    LV + D I       
Sbjct: 58  GTSHEYSPTTVPYRANIFALKQAGVTHVIASNAVGSLREEISPRMLV-IPDQIY------ 110

Query: 145 MVGLNDDRFGER---FFS--------LANAYDAEYRALLQKVAKEEGFP----LTEGVFV 189
                 DR   R   FFS         A  Y  E R+++  VA E        + +G +V
Sbjct: 111 ------DRTKHRTSTFFSDGIVAHQQFATPYCTELRSIVTDVAMENTAADIDIVKDGTYV 164

Query: 190 SYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKL 249
              GP F T AE    +  G D++GM+ +PE   AR  +L  V ++ +T+      D ++
Sbjct: 165 CIEGPQFSTRAESEFYRSQGWDIIGMTTIPEAKLAREAELAYVTIAGVTDYDVWKEDTQV 224

Query: 250 SHAQTLAAAELSKQNFINLICGFLRKI 276
           +  + L+ AE +++   +++   +  I
Sbjct: 225 TLEEVLSNAERNQKAIKSVLTAVINTI 251


>UniRef50_B1I2E1 Methylthioadenosine phosphorylase n=33 Tax=cellular organisms
           RepID=B1I2E1_DESAP
          Length = 292

 Score = 67.8 bits (164), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 32/86 (37%), Positives = 51/86 (59%)

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           G + +  GP FE+ AEIRM++ +G D+ GM+ VPEV+ AR   +    +  +TN A G+S
Sbjct: 155 GTYAATEGPRFESPAEIRMLRHLGADLAGMTGVPEVVLAREAGICYATICMVTNFAAGIS 214

Query: 246 DVKLSHAQTLAAAELSKQNFINLICG 271
             +L+H + L A  ++     +LI G
Sbjct: 215 PHRLTHEEVLEAMRVNAAKIRSLIAG 240


>UniRef50_Q5Z1K2 Putative methylthioadenosine phosphorylase n=4
           Tax=Corynebacterineae RepID=Q5Z1K2_NOCFA
          Length = 269

 Score = 66.6 bits (161), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 69/256 (26%), Positives = 107/256 (41%), Gaps = 20/256 (7%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH-AGELVLGHLQGVPV--VCM 82
           P +A I G+G     D     V I           T +G  +  + +G + G PV  V  
Sbjct: 7   PALAVIGGTGFYDFFDTATQDVEID----------TPYGAPSAPIAVGEVAGRPVAFVPR 56

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            G+ H Y    +  + + +   + LG   +F   A GSLR + G G++   +  ++   G
Sbjct: 57  HGKRHEYAPHTLPYLAN-MWALRSLGVRRIFAPCAVGSLRADWGPGTVAVPEQLVDRTSG 115

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAE 201
            P    +    G    S A+ Y  E R      A EE  P+  G   V   GP F T AE
Sbjct: 116 RPQTYFDG---GGVHVSFADPYCDELRGAAIGSAVEE-LPMQPGGTMVVVQGPRFSTRAE 171

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA-QTLAAAEL 260
            R     G D+V M+  PE + AR  ++   AV+ +T++  GL   +  HA    A  + 
Sbjct: 172 SRWFAGQGWDLVNMTGYPEAVLARELEMCYCAVALVTDLDAGLESGEGVHAVDVFAEFKR 231

Query: 261 SKQNFINLICGFLRKI 276
           + + F  LI G +  +
Sbjct: 232 NIEPFKELIRGAISAV 247


>UniRef50_C0W926 Purine-nucleoside phosphorylase n=1 Tax=Actinomyces urogenitalis
           DSM 15434 RepID=C0W926_9ACTO
          Length = 286

 Score = 66.6 bits (161), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 59/221 (26%), Positives = 93/221 (42%), Gaps = 25/221 (11%)

Query: 31  ILGSGL-GALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP---------VV 80
           +LGSG  GAL    E    +    LPG       GH  +L+  + + +P         V+
Sbjct: 45  VLGSGADGALEGWGEPEATLPLSDLPGVLAPAAPGHR-DLLASYRRTLPGDDGDRGLRVL 103

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
              GR H YEG G   +    R     G       NA G LR +   G ++ + DH+N  
Sbjct: 104 VAYGRTHLYEGHGSAPVVALARAAAAAGVRAAVLVNANGCLR-DWRLGEVMTITDHLNLT 162

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAA 200
             +P  G         F  +   +D     +L+K  + EG       + +  GP ++T A
Sbjct: 163 GSSPFDGTV-------FVDVREVWDRRLAQVLRKRTEREG------TYAALRGPEYQTMA 209

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA 241
           E R +   G D VGMS V E I+     ++V  +S +++++
Sbjct: 210 ETRWLAGGGADAVGMSTVLEAIALHQLGVRVAGMSVVSDLS 250


>UniRef50_C8R2U4 Methylthioadenosine phosphorylase n=1 Tax=Desulfurivibrio
           alkaliphilus AHT2 RepID=C8R2U4_9DELT
          Length = 254

 Score = 66.6 bits (161), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 65/227 (28%), Positives = 98/227 (43%), Gaps = 19/227 (8%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQG--VPVVCMKGR 85
           V  I GSGL      IENA  ++ +   G P       +  L+ G + G  V ++   GR
Sbjct: 4   VGIIGGSGLEN-PQLIENAREVTVDTPYGPP-------SAPLLRGRIGGREVALLARHGR 55

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H      +    + +   +  GC  L  + A GSLR ++G G LV + D +        
Sbjct: 56  EHTIPPSQVNNRANLL-ALQEQGCTHLLASAACGSLRQDIGPGELV-IPDQLIDFTRFRA 113

Query: 146 VGLNDDRF-----GERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETA 199
           V  +D  F       R  +LA+ + AE R  L    +    PL +G   ++  GP F T 
Sbjct: 114 VTFHD-HFPPGIENARHTALADPFAAEIRKQLLMAGRHLELPLHDGGTMLTIEGPRFSTR 172

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD 246
           AE RM Q+ G D+V M++ PE + A    L    V+ +T+      D
Sbjct: 173 AESRMFQLWGADLVNMTIAPEAVLAAELGLPYAVVAMVTDYDSWKED 219


>UniRef50_Q11FN7 Methylthioadenosine phosphorylase n=1 Tax=Chelativorans sp. BNC1
           RepID=Q11FN7_MESSB
          Length = 276

 Score = 65.9 bits (159), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 2/140 (1%)

Query: 107 LGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDA 166
           LG E +   NA GS+ P +  G +V   D ++          ++     R     + +  
Sbjct: 74  LGVESIISQNAIGSVNPAIRPGDIVISDDFLDKTKSRAQSLFDESECWVRV-DFTDPFCP 132

Query: 167 EYRA-LLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISAR 225
             R  L++   +     +  G FV   GP FET AEIR   + GGD+VG  +VPEVI AR
Sbjct: 133 RLRTNLIEAANRHSNRVIHRGTFVCTEGPRFETPAEIRAYAMEGGDIVGTPLVPEVIFAR 192

Query: 226 HCDLKVVAVSAITNMAEGLS 245
             ++   +++ + N   G++
Sbjct: 193 ELEMCFASIAPVINFGAGMA 212


>UniRef50_Q2LVG5 Phosphorylase family 2 protein n=1 Tax=Syntrophus aciditrophicus SB
           RepID=Q2LVG5_SYNAS
          Length = 240

 Score = 65.5 bits (158), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 52/172 (30%), Positives = 85/172 (49%), Gaps = 13/172 (7%)

Query: 109 CEL----LFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAY 164
           CEL    +   N+AGSL  +   G+++   D I  + G P  G++  +       L    
Sbjct: 71  CELSVREIVAINSAGSLHRKWKPGTIMVPDDFI-MLTGIP--GIHQTQAAH----LTPQL 123

Query: 165 DAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVIS 223
           D + R  L + A+EEG  + + GV+   PGP  ET AEIRM+     D+VGM++  E ++
Sbjct: 124 DLKVRHYLLEAAREEGVNVIDRGVYWQMPGPRLETRAEIRMISRFA-DLVGMTLASEAVT 182

Query: 224 ARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRK 275
           A+   L   A+ +I N   GL +  L+  + +A A  + +  I +   +L K
Sbjct: 183 AQELGLAYGALCSIDNYGNGLVEKLLTVEEIVAHARENARVMIGIATRYLEK 234


>UniRef50_B5ICA6 Phosphorylases family 2 n=2 Tax=Aciduliprofundum boonei T469
           RepID=B5ICA6_9EURY
          Length = 224

 Score = 65.1 bits (157), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 15/147 (10%)

Query: 125 VGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSL-------ANAYDAEYRALLQKVAK 177
           V   ++ +LKD+I   PG+ ++  N   F  R ++         N Y+   + L  K+ +
Sbjct: 73  VAISTVGSLKDNIK--PGSFLLPSNLLDFTNRVWTYHDNEPYHVNMYEPFCKELRVKINE 130

Query: 178 EEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAI 237
           +   PL  G + +  GP FETAAE  M++I+G D+VGM+V PE   A+  +L    +  +
Sbjct: 131 KLSIPLG-GTYATMKGPQFETAAEANMLRILGADIVGMTVAPEAKLAKELNLCYQPICIV 189

Query: 238 TNMAEGLSDVKLSHAQTLAA-AELSKQ 263
            N  +G    K SH + L    EL++Q
Sbjct: 190 VNYVDG----KTSHKENLKVMKELNEQ 212


>UniRef50_Q2FR33 Methylthioadenosine phosphorylase n=1 Tax=Methanospirillum hungatei
           JF-1 RepID=Q2FR33_METHJ
          Length = 224

 Score = 64.7 bits (156), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 43/169 (25%), Positives = 77/169 (45%), Gaps = 11/169 (6%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSL 160
           I   KL G + +    + GSL+ ++  GS V   D I   P   ++    D     F   
Sbjct: 59  IAALKLAGADRIIALGSTGSLQEDIPPGSRVIPDDFICLTPVPTIMNHTIDHVNPEF--- 115

Query: 161 ANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPE 220
               DA+ R LL K++ E    +  G ++   GP  E+ AEI  M+    D+VGM++  E
Sbjct: 116 ----DADLRTLLMKLSPEA---IQRGTYIQTRGPRLESKAEISWMKRFA-DIVGMTIGSE 167

Query: 221 VISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLI 269
           +  A    L   A+  + N A G+ D ++++   +     +++  ++L+
Sbjct: 168 LTVAAELGLPFAAICTVDNYANGVCDAQITYESIIRTVRENQEKALDLL 216


>UniRef50_Q13126 S-methyl-5'-thioadenosine phosphorylase n=55 Tax=cellular organisms
           RepID=MTAP_HUMAN
          Length = 283

 Score = 64.7 bits (156), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 51/181 (28%), Positives = 81/181 (44%), Gaps = 15/181 (8%)

Query: 69  LVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDA------IRTFKLLGCELLFCTNAAGSLR 122
           L+LG ++ V  V +        GR  TIM         I   K  GC  +  T A GSLR
Sbjct: 45  LILGKIKNVDCVLLA-----RHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLR 99

Query: 123 PEVGAGSLVALKDHINTMPGTPMV---GLNDDRFGERFFSLANAYDAEYRALLQKVAKEE 179
            E+  G +V +   I+     P     G +    G     +A  +  + R +L + AK+ 
Sbjct: 100 EEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKL 159

Query: 180 GFPL-TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
           G    ++G  V+  GP F + AE  M +  G DV+ M+ VPEV+ A+   +   +++  T
Sbjct: 160 GLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMAT 219

Query: 239 N 239
           +
Sbjct: 220 D 220


>UniRef50_A0L8V4 Methylthioadenosine phosphorylase n=1 Tax=Magnetococcus sp. MC-1
           RepID=A0L8V4_MAGSM
          Length = 241

 Score = 64.3 bits (155), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 39/92 (42%), Positives = 50/92 (54%), Gaps = 4/92 (4%)

Query: 164 YDAEYRA-LLQKVAKEEGF--PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPE 220
           +D  +R  +L      E F  P+  GV+    GP FET AEIRM Q    DVVGM+V  E
Sbjct: 123 FDPAWRQQILAAWPPSESFGAPVDGGVYWQTRGPRFETQAEIRMYQAFT-DVVGMTVASE 181

Query: 221 VISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
            I AR  DL   A+  + N A G+SD  L++A
Sbjct: 182 CILARELDLAYAAICIVDNYANGISDEPLTYA 213


>UniRef50_C5EEL8 Purine nucleoside phosphorylase n=1 Tax=Clostridiales bacterium
           1_7_47FAA RepID=C5EEL8_9FIRM
          Length = 259

 Score = 63.9 bits (154), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 53/184 (28%), Positives = 78/184 (42%), Gaps = 4/184 (2%)

Query: 63  HGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSL 121
           +G + E+  G +QG  V  +   G  ++     I   A I  FK LG E +  TN  GS 
Sbjct: 28  YGRSSEIFEGTIQGRKVYFLPRHGEEHKIIVPRINYRANIWAFKELGVEQILATNCVGSS 87

Query: 122 RPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE--E 179
            P++  GSLV   D  +     P   L DD        +  AY  + R  L   A +   
Sbjct: 88  NPDIELGSLVIPHDFCDWTRRFPR-SLYDDEVEAYHVDMTPAYCPDLRRALIDAANKVKP 146

Query: 180 GFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
           G    + V     G  FET  E+ M + +G D++GM+ +PE + AR   +    +   TN
Sbjct: 147 GHVHDKAVIFVNEGLRFETPFELTMFRKLGADLIGMTTLPEAVFAREAAICYAHICVPTN 206

Query: 240 MAEG 243
              G
Sbjct: 207 WCLG 210


>UniRef50_Q7ZV22 Methylthioadenosine phosphorylase n=20 Tax=Metazoa
           RepID=Q7ZV22_DANRE
          Length = 280

 Score = 62.4 bits (150), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 62/222 (27%), Positives = 94/222 (42%), Gaps = 21/222 (9%)

Query: 27  RVAFILGSGLGA---LADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM- 82
           ++  I GSGL     L  + E  V   Y    G P       +  L+LG ++ V  V + 
Sbjct: 8   KIGIIGGSGLDDPDILEGRTERYVVTPY----GKP-------SDALILGKIKNVDCVLLA 56

Query: 83  -KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALK---DHIN 138
             GR H      +    + I   K  GC  L  T A GSLR ++  G +V +    D   
Sbjct: 57  RHGRQHTIMPTNVNYQAN-IWALKEEGCTHLLVTTACGSLREDIQPGDIVLIDQFIDRTT 115

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFE 197
               T   G      G     +A  + ++ R +L +VA+  G    T G  V+  GP F 
Sbjct: 116 KRVQTFYDGQPTSPPGVCHIPMAEPFCSKTREVLLEVAQGLGVKCHTRGTMVTIEGPRFS 175

Query: 198 TAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
           + AE  M +  G DV+ M+ VPEV+ A+   L   +++  T+
Sbjct: 176 SRAESLMFRQWGADVINMTTVPEVVLAKEAGLCYASIAMATD 217


>UniRef50_Q21JS6 Methylthioadenosine phosphorylase n=1 Tax=Saccharophagus degradans
           2-40 RepID=Q21JS6_SACD2
          Length = 252

 Score = 62.0 bits (149), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 65/226 (28%), Positives = 97/226 (42%), Gaps = 15/226 (6%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++A I GSG   +A    NA A++       PV+T +G  G L+   + G  +V +   G
Sbjct: 4   KIAVIGGSGFYTMASA-NNAKALN-------PVNTPYGSVGGLIEYSMGGHNIVFLARHG 55

Query: 87  HFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
             ++     I   A I   K LG   +   NA G +    G G LV     I+   G   
Sbjct: 56  GEHKLPPHKINYRANIYALKELGVSHIIAANAVGGIGERCGPGVLVIPDQLIDYTFGREG 115

Query: 146 VGLNDDRFGERFFSLANAYDAEYR-ALLQKVA---KEEGFP--LTEGVFVSYPGPNFETA 199
              +    G         ++   R AL+Q  A   KE G    +  GV+    GP  ETA
Sbjct: 116 TFFDSFEDGMSHIDFTYPFEGRVRNALIQASAAFEKEFGSDKVVRNGVYACMQGPRLETA 175

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           AEI+ ++  G  +VGM+ +PE   AR   +   ++  + N A GLS
Sbjct: 176 AEIKKLKNDGASLVGMTAMPEAALARELGIDYASICLVVNWAAGLS 221


>UniRef50_Q1PVD3 Similar to 5'-methylthioadenosine phosphorylase n=1 Tax=Candidatus
           Kuenenia stuttgartiensis RepID=Q1PVD3_9BACT
          Length = 294

 Score = 62.0 bits (149), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 43/147 (29%), Positives = 68/147 (46%), Gaps = 3/147 (2%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSL 160
           I   K LG + +   +  G++      G  V + D I+   G           G  F   
Sbjct: 78  IYALKELGAKQIVSWSGPGAMNENYKIGEYVLIDDIIDETHGRESTFYK--HLGIGFIRQ 135

Query: 161 ANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVP 219
              +    R  +    K  G  +T +GV+V   GP  ET AEIR  ++ GGD+VGM++VP
Sbjct: 136 FPVFCPTLRESILHTLKFLGIGITGKGVYVCTQGPRLETPAEIRKYKLYGGDLVGMTLVP 195

Query: 220 EVISARHCDLKVVAVSAITNMAEGLSD 246
           EV  A+  ++   ++  +TN AEG++ 
Sbjct: 196 EVFLAKELEMCYASICYVTNYAEGIAS 222


>UniRef50_O28486 Methylthioadenosine phosphorylase (MtaP) n=1 Tax=Archaeoglobus
           fulgidus RepID=O28486_ARCFU
          Length = 243

 Score = 62.0 bits (149), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 53/221 (23%), Positives = 100/221 (45%), Gaps = 12/221 (5%)

Query: 59  VSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNA 117
           + T +G A E+ +G + G+ V  ++  G   +     I   A     K LG + +    +
Sbjct: 24  IETPYGTA-EIDVGRVDGIDVAIIQRHGKRKDKPPHRINHAANFYALKSLGVKYVIGMGS 82

Query: 118 AGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAK 177
            G+LR E    SL+   D+I+   G  +       + +    +   +D   R +L +VA+
Sbjct: 83  VGALREEYSLPSLIIPHDYIDFFSGVTI-------YNDSLVHVTPGFDEYLREVLVEVAR 135

Query: 178 E-EGFP-LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVS 235
           +   FP + +GV+    GP  ET AEI M++    D VGM+   E   AR   L    V 
Sbjct: 136 KISSFPVIDKGVYFQTRGPRLETKAEIAMIKSF-ADCVGMTAGSEATIARELGLSYAIVC 194

Query: 236 AITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
            + N A G+ +  + + + +  A+ + +  + ++   ++K+
Sbjct: 195 TMDNYAHGIKNQSIDYREIVEKAKENARECLKIVEEAVKKV 235


>UniRef50_B3T2V4 Putative phosphorylase family 2 n=2 Tax=environmental samples
           RepID=B3T2V4_9ARCH
          Length = 268

 Score = 61.6 bits (148), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 46/185 (24%), Positives = 83/185 (44%), Gaps = 7/185 (3%)

Query: 59  VSTVHGHAGE-LVLGHLQGVPVVCM--KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCT 115
           + T +G   + + +G  +G  +  M   G+ H      +    + +  FK LG   +   
Sbjct: 30  IETPYGKTSDTITIGEFKGKKIAFMPRHGKKHSIPPHMINYCAN-VWAFKELGITRIVSP 88

Query: 116 NAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKV 175
           +A GSL+ E+  G+ V     I+           D R      S+A+ +  E + ++ + 
Sbjct: 89  SAVGSLKEEIKPGNFVLPTQFIDFTKSRKNSFSEDGRV--IHISVADPFCPELQEIVSET 146

Query: 176 AKEEGFPL-TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAV 234
           A  +G  L  +  +    GP F T AE R  +  G D++GM++VPE   AR   +  V++
Sbjct: 147 ANNQGITLHKDCTYACIEGPRFSTKAESRFYKSTGSDIIGMTLVPECQLAREAQICYVSI 206

Query: 235 SAITN 239
           S +T+
Sbjct: 207 STVTD 211


>UniRef50_A9B0Q9 Purine phosphorylase family 2 n=1 Tax=Herpetosiphon aurantiacus
           ATCC 23779 RepID=A9B0Q9_HERA2
          Length = 253

 Score = 61.6 bits (148), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 44/150 (29%), Positives = 67/150 (44%), Gaps = 11/150 (7%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLND------DRFG 154
           I   K LG + +   N  G++   +    LV L   +N     P+    D       +  
Sbjct: 71  IWAAKELGYQNILSWNGVGAINQLLQVHDLVVLNHVLNGTKTRPINFAGDLPNASAWQIA 130

Query: 155 ERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVG 214
           +R F  A+A       L Q+  + +      G +    GP  ETAAEIR     G DVVG
Sbjct: 131 QRVFDPASA-----SVLYQQARRYQARSFDCGTYACSEGPRLETAAEIRAWANFGADVVG 185

Query: 215 MSVVPEVISARHCDLKVVAVSAITNMAEGL 244
           M++VPEV+ A    +K  +++ +TN A G+
Sbjct: 186 MTLVPEVLLAYELGIKFASLAYVTNFATGV 215


>UniRef50_Q47F96 Methylthioadenosine phosphorylase n=7 Tax=Betaproteobacteria
           RepID=Q47F96_DECAR
          Length = 256

 Score = 61.6 bits (148), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 60/222 (27%), Positives = 100/222 (45%), Gaps = 18/222 (8%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHA-GELVLGHLQGVPVVCM--KG 84
           +A I GSGL  L++     + +S+ ++    V T +G A G LV G + G P V +   G
Sbjct: 2   LAIIGGSGLTTLSN-----LDVSHREV----VRTPYGEASGALVFGQICGQPAVFLPRHG 52

Query: 85  RGHFYEGRGMTIMTD--AIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            GH      +    +  A+   K+ G   +    + GS+R ++  G +V     I+   G
Sbjct: 53  YGHTIPPHMVNYRANMWALHHHKVSG---VISVASVGSIRGDLQPGDIVLPHQIIDYTWG 109

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAE 201
                 + +          + YD E R  + +  ++    +  G V+ +  GP  ETAAE
Sbjct: 110 RKSTFFDGNGTPVNHIDFTDPYDPELRRRILEAGEQLSIDVKVGAVYAATQGPRLETAAE 169

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG 243
           I  ++  G DVVGM+ +PE + AR       A++ + N A G
Sbjct: 170 INRLERDGADVVGMTGMPEAVLARELGTPYAAINVVANHAAG 211


>UniRef50_Q4P1A5 Putative uncharacterized protein n=1 Tax=Ustilago maydis
           RepID=Q4P1A5_USTMA
          Length = 180

 Score = 61.6 bits (148), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 32/73 (43%), Positives = 39/73 (53%), Gaps = 5/73 (6%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP-----V 79
           +P+   I GSGL  LA  +E+AV + Y  +PGF  STV GH   L  G+L   P     V
Sbjct: 30  SPKWGIICGSGLSGLASTLESAVHVPYTSIPGFAESTVQGHTSSLAFGYLSTTPSKRVAV 89

Query: 80  VCMKGRGHFYEGR 92
           V   GR H YEG 
Sbjct: 90  VACLGRFHTYEGH 102



 Score = 56.6 bits (135), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 29/72 (40%), Positives = 42/72 (58%), Gaps = 2/72 (2%)

Query: 157 FFSLANAYDAEYRALLQKVAKEEGF--PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVG 214
           F  L+NAYD E R  L + A++      L  G +    GP++E+ A+   ++ +G D VG
Sbjct: 107 FPPLSNAYDLELRLALYRAAEKLSLLDSLASGTYAYVLGPSYESRADANFLKSVGADAVG 166

Query: 215 MSVVPEVISARH 226
           MS VPEVI+A H
Sbjct: 167 MSTVPEVIAAAH 178


>UniRef50_Q16MW6 Methylthioadenosine phosphorylase n=6 Tax=Neoptera
           RepID=Q16MW6_AEDAE
          Length = 279

 Score = 61.2 bits (147), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 54/188 (28%), Positives = 86/188 (45%), Gaps = 8/188 (4%)

Query: 59  VSTVHGHAGE-LVLGHLQGVPVVCM--KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCT 115
           VST  G+  + L+ G + GV  V +   GR H      +    + I   K +GC  +  +
Sbjct: 29  VSTHFGNPSDVLIEGKIAGVDCVLLARHGRNHSIMPSNVNYRAN-IWALKTVGCTHVIVS 87

Query: 116 NAAGSLRPEVGAGSLVALKDHIN--TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQ 173
            A GSL+  +  G LV   + I+  T         ND   G     +  A+ +  R +L 
Sbjct: 88  TATGSLQERIHPGDLVIPDNFIDRTTKRAQTFYDGNDMLVGVCHVPMEPAFCSRTREVLI 147

Query: 174 KVAKEEGFP--LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKV 231
           + AKE G      +G  V+  GP F + AE  + +  G D+V M++VPEV+ A+   L  
Sbjct: 148 ETAKELGLVGVHNKGTVVTIEGPRFSSKAESNLFRQWGADLVNMTLVPEVVLAKEAGLCY 207

Query: 232 VAVSAITN 239
            A++  T+
Sbjct: 208 AAIAMATD 215


>UniRef50_C6DE56 Methylthioadenosine phosphorylase n=1 Tax=Pectobacterium
           carotovorum subsp. carotovorum PC1 RepID=C6DE56_PECCP
          Length = 301

 Score = 61.2 bits (147), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 70/253 (27%), Positives = 109/253 (43%), Gaps = 33/253 (13%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPV--VCMK 83
           PR+  I GSG+ +L+  IE    I+     G P       +G + LG + GVPV  V   
Sbjct: 10  PRIGIICGSGMDSLS-IIEAPERINVTTSFGDP-------SGIITLGEIAGVPVAIVNRH 61

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHI------ 137
           G GH      + +  + I   K LG   +   +A GSL  E   G+ VA+  +I      
Sbjct: 62  GIGHRLLPSEINVRAN-IAALKALGVSQVISFSAVGSLVEEAPPGTFVAIDQYIDRTYRR 120

Query: 138 -NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP-LTEGVFVSYPGPN 195
            NT  G+ +V                    +  +LL     E   P L +G++V   GP+
Sbjct: 121 VNTFFGSGVVA---------HVPFGKPVCTDNHSLLVDALGELSIPHLAKGLYVVMEGPH 171

Query: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL 255
           F T AE    + +GG V+GM+ +PE    R  +L    V+ +T+      D   +  + +
Sbjct: 172 FSTKAESAFHRQMGGTVIGMTAMPEPKLCREAELCYNMVAMVTDY-----DCWHTSHEAV 226

Query: 256 AAAELSKQNFINL 268
            AA +S+Q   N+
Sbjct: 227 NAAMVSEQMADNI 239


>UniRef50_A7BPC6 Purine phosphorylase, family 2 n=2 Tax=Gammaproteobacteria
           RepID=A7BPC6_9GAMM
          Length = 181

 Score = 61.2 bits (147), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 47/175 (26%), Positives = 75/175 (42%), Gaps = 1/175 (0%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSL 160
           I + K LG + +    A G + PE+    LV     I+           D+         
Sbjct: 7   IGSIKALGIKTVIAVAAVGGIHPEMRPKDLVIPHQMIDYTYSREQTFFADEFNHVTHIDF 66

Query: 161 ANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVP 219
              Y  E R  L K A+   F + ++GV+ +  GP  ETAAEI  M+  G D+VGM+ +P
Sbjct: 67  TQPYCDELREQLLKAAESFDFKVHSQGVYGATQGPRLETAAEINRMEREGCDIVGMTGMP 126

Query: 220 EVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLR 274
           E   AR  +L     + + N A G    +++  +  A  +   +N   L+   +R
Sbjct: 127 EAALARELELCYATCAVVANPAAGRGSAQITMTEIEATLKQGIENVRQLLGVVIR 181


>UniRef50_B4U6Q8 Purine phosphorylase family 2 n=2 Tax=Aquificaceae
           RepID=B4U6Q8_HYDS0
          Length = 280

 Score = 60.5 bits (145), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 49/91 (53%)

Query: 185 EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL 244
           +GV+    GP FET  E+ M++ +G D+VGM+  PEV  AR   + ++ +S ITN A G+
Sbjct: 172 KGVYACTEGPRFETKKEVEMLKHLGADMVGMTACPEVFLARETGMHILHISVITNPAAGI 231

Query: 245 SDVKLSHAQTLAAAELSKQNFINLICGFLRK 275
              KL+  + +   +   +     +  F+ K
Sbjct: 232 EGHKLTSKEVIDMMKQKDEEIKKFLTLFIPK 262


>UniRef50_C7LA98 FI12502p (Fragment) n=14 Tax=Drosophila RepID=C7LA98_DROME
          Length = 304

 Score = 60.5 bits (145), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 52/195 (26%), Positives = 81/195 (41%), Gaps = 16/195 (8%)

Query: 57  FPVSTVHGHAGELVL-GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIR------TFKLLGC 109
           + V T  G   ++++ G ++GV V C+  R     GR   IM   I         + +GC
Sbjct: 54  YAVCTPFGKPSDVIIDGQIEGVNV-CLLSRN----GRNHDIMPSNINYRANVWAMRKMGC 108

Query: 110 ELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV---GLNDDRFGERFFSLANAYDA 166
             +  TN   SLR     G LV   D I+           G      G     +   +  
Sbjct: 109 THILVTNTFSSLRDTFQPGHLVVPNDVIDYTSRRAQTFYDGAVGSPLGVCHVPMNPTFCE 168

Query: 167 EYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISAR 225
             R  L   A+E GFP  + G  ++  GP + T AE  M +  G D++ M++ PE I A+
Sbjct: 169 RTRQHLLSAAEELGFPTGSSGTVLTLEGPRYSTVAENNMFRKWGADLLSMTLCPEAILAK 228

Query: 226 HCDLKVVAVSAITNM 240
              +   ++  +TNM
Sbjct: 229 EAGIPYASLGLVTNM 243


>UniRef50_A0B8I0 Methylthioadenosine phosphorylase n=1 Tax=Methanosaeta thermophila
           PT RepID=A0B8I0_METTP
          Length = 245

 Score = 59.7 bits (143), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 36/90 (40%), Positives = 53/90 (58%), Gaps = 2/90 (2%)

Query: 160 LANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVP 219
           ++  Y  E R +L +  + EG    EGV+V   GP+FET A+I+M++   GDVVGM+  P
Sbjct: 116 MSEPYCPEIRKVLMESCRAEGHEPYEGVYVCTEGPHFETHAQIKMLRSF-GDVVGMTGYP 174

Query: 220 EVISARHCDLKVVAVSAITNMA-EGLSDVK 248
           EV+ AR   L   ++   TN A EG  D++
Sbjct: 175 EVVLARERGLCYASICLATNKAGEGQFDLR 204


>UniRef50_B1ZY09 Purine phosphorylase family 2 n=2 Tax=Opitutaceae
           RepID=B1ZY09_OPITP
          Length = 232

 Score = 59.7 bits (143), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 47/154 (30%), Positives = 76/154 (49%), Gaps = 9/154 (5%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSL 160
           IR    LG + +   N+ GSL+ ++  G+ V+  D++    G PM   + +  G      
Sbjct: 63  IRALADLGFKDILSLNSVGSLKRDLPPGTFVSCSDYVGLQQG-PMTFFDQELKG----GA 117

Query: 161 ANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVP 219
               +     L++K+A E  F +  G V+V + GP FET AEIR++Q   GDVVGM+   
Sbjct: 118 PGIANNLIPLLIEKLAPE--FKIHPGKVYVQFRGPRFETKAEIRIVQSW-GDVVGMTAAH 174

Query: 220 EVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQ 253
           E        L+  +++ I N A GL   ++  A+
Sbjct: 175 EADLCSELGLRYNSLALIDNYANGLEGTEIDFAK 208


>UniRef50_Q5KPU2 Glutamate biosynthesis-related protein, putative n=2
           Tax=Agaricomycotina RepID=Q5KPU2_CRYNE
          Length = 303

 Score = 59.7 bits (143), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 47/153 (30%), Positives = 67/153 (43%), Gaps = 22/153 (14%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRF------- 153
           I   K +GCE +   +A GSLR E+  G  +     I+   G     + +D F       
Sbjct: 76  IAALKHIGCEAIIAFSAVGSLREEIAPGHFIIPDQIIDRTKG-----IREDTFFRGEGLV 130

Query: 154 -----GERFFSLANAYDAEYRALLQKVAKEEGFPL--TEGVFVSYPGPNFETAAEIRMMQ 206
                GE F    NA+ A     ++K+ KE G  +  T    V   GP F T AE  M +
Sbjct: 131 VHSMFGEPFSQKLNAFVA---PRVEKILKETGDVVLHTGKTVVCMEGPAFSTRAESLMYR 187

Query: 207 IIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
             GGD++ MSV+PE   AR  +L    +   T+
Sbjct: 188 QWGGDIINMSVIPEAKLAREAELDYTLICTSTD 220


>UniRef50_Q3ZZT2 Methylthioadenosine phosphorylase n=7 Tax=cellular organisms
           RepID=Q3ZZT2_DEHSC
          Length = 294

 Score = 59.3 bits (142), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 52/181 (28%), Positives = 78/181 (43%), Gaps = 20/181 (11%)

Query: 69  LVLGHLQGVPVVCM--KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVG 126
           +V G+L GV V  +   GRGH      +    + I   K LG E +   N+ GS + EV 
Sbjct: 40  IVTGNLNGVGVAFLPRHGRGHRILPSEIPSRAN-IYALKSLGVEHIIAVNSVGSFKKEVK 98

Query: 127 AGSLV-------ALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE 179
            G L+             NT  G  +V            + +  +    R LL + AKE 
Sbjct: 99  PGHLLIPDQLIDRTSQRTNTFFGKGIVA---------HIAFSQPFCPNLRKLLFECAKEA 149

Query: 180 GFPLTEG-VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
           G  +  G  +V   GP F T AE R+ +  G DV+GM+ +PE   AR  ++    ++  T
Sbjct: 150 GANVHNGGTYVVMEGPAFSTQAESRLHKSWGADVIGMTALPEAKLAREAEICYAIIACAT 209

Query: 239 N 239
           +
Sbjct: 210 D 210


>UniRef50_B5YKP5 S-methyl-5-thioadenosine phosphorylase n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YKP5_THEYD
          Length = 265

 Score = 58.9 bits (141), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 48/166 (28%), Positives = 78/166 (46%), Gaps = 10/166 (6%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGER---- 156
           I  FK  G E +F   A GSL   +  GS+V     I+   G     +  + F E     
Sbjct: 73  IYGFKNFGIERIFGVFATGSLTENIPPGSIVIPNQIIDFTQG-----MRANTFYEEKKVV 127

Query: 157 FFSLANAYDAEYRALLQKVAKEEGFP-LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGM 215
                  + +E R  L + A++ G   ++   ++   GP  ETAAEI+  + IG D++GM
Sbjct: 128 HIDFTEPFCSEIRHYLLETARKIGINVISHATYICVNGPRLETAAEIKFFKNIGADIIGM 187

Query: 216 SVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELS 261
           +++PE   AR  ++   AV+ + N A G+S   L+  + +   E S
Sbjct: 188 TIMPEASLAREVEICYAAVAVVANYAAGISKFPLTVKEVIETMEDS 233


>UniRef50_Q0SDK3 Probable S-methyl-5-thioadenosine phosphorylase n=2 Tax=Rhodococcus
           RepID=Q0SDK3_RHOSR
          Length = 260

 Score = 58.5 bits (140), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 43/158 (27%), Positives = 68/158 (43%), Gaps = 10/158 (6%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGER--FF 158
           I     LG   +     +GSLRP +G GS+V     ++        G  DD F +     
Sbjct: 72  IWALHSLGVRTILAPTPSGSLRPAIGVGSVVVPDQLVD------RTGRTDDTFHDDDVHI 125

Query: 159 SLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIRMMQIIGGDVVGMSV 217
           S A+ + A  R  +    +  G+ + +G V V+  GP F T AE R     G D++ M+ 
Sbjct: 126 SFADPFCAHGRRAVVSTLRRNGWVVNDGGVMVAIRGPRFSTRAESRWYAAQGWDLISMTP 185

Query: 218 VPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL 255
            PE   AR   +    ++ +T+  + +SD      Q L
Sbjct: 186 YPEAALARELGMSYTCIALVTDH-DVISDTPWPVTQDL 222


>UniRef50_C1HCE7 Purine nucleoside phosphorylase n=1 Tax=Paracoccidioides
           brasiliensis Pb01 RepID=C1HCE7_PARBA
          Length = 243

 Score = 58.5 bits (140), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 51/158 (32%), Positives = 72/158 (45%), Gaps = 15/158 (9%)

Query: 26  PRVAFILGSGLGALADQIENA--VAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
           PR A I GSGLG LA+ +  +      Y  +P FPVST +    +  +  L+        
Sbjct: 28  PRFAIICGSGLGGLAESVNKSPKAEFDYASIPHFPVSTGNLCVVKERITQLESTWPGSFN 87

Query: 84  GRGHFYEG---RGMTIMTDAIR------TFKLLGCELLFCTNAAGSLRPEVGAGSLVALK 134
              +  +        +   A+        F +LG E +  T+AAG L PE   G +V L 
Sbjct: 88  NEVYLPDNVSNDDANVNACAVPGHVGKLVFGILG-ENIAVTSAAGGLNPEYEVGDIVILN 146

Query: 135 DHI--NTMPGT-PMVGLNDDRFGERFFSLANAYDAEYR 169
           DHI    + G  P+ G ND+ FG RF  L++AYD   R
Sbjct: 147 DHIFLAGLAGIHPLRGANDNEFGVRFPPLSDAYDLGLR 184


>UniRef50_A3DD28 Methylthioadenosine phosphorylase n=7 Tax=Clostridia
           RepID=A3DD28_CLOTH
          Length = 268

 Score = 58.2 bits (139), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 43/146 (29%), Positives = 64/146 (43%), Gaps = 11/146 (7%)

Query: 105 KLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGE----RFFSL 160
           K LG + +    ++GSLR ++  G  V     ++   G        D F +    +  S 
Sbjct: 75  KKLGVKKILAPTSSGSLRADIKPGDFVICDQFVDRTTG------RKDTFYDGPVTKHISS 128

Query: 161 ANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVP 219
           A+ Y  E R +  +V K+ G    E G  V   GP F T AE R    +G DV+ M+  P
Sbjct: 129 AHPYCPELRKIAIQVGKDLGITTHEKGTVVVIQGPRFSTVAESRWFSKMGWDVINMTQYP 188

Query: 220 EVISARHCDLKVVAVSAITNMAEGLS 245
           EV  AR   +    ++ IT+   GL 
Sbjct: 189 EVYLARELGICYANIALITDYDAGLE 214


>UniRef50_B0DVC8 Predicted protein n=3 Tax=Basidiomycota RepID=B0DVC8_LACBS
          Length = 315

 Score = 57.8 bits (138), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 68/252 (26%), Positives = 101/252 (40%), Gaps = 38/252 (15%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTV------HGHAGELVLGHLQG--VPV 79
           +  I GSGL  L D +     ++ E   GFP S++       G     +  H QG  +P 
Sbjct: 9   IGIIGGSGLYHL-DNLTQITTVNPETPWGFPSSSITIAALPSGTRVAFLARHGQGHVIPP 67

Query: 80  VCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINT 139
             + GR +             I   K LG   +   +A GSLR E+  GS V     I+ 
Sbjct: 68  SSVPGRAN-------------IAALKSLGVRAIIAFSAVGSLREEISPGSFVLPTQIIDR 114

Query: 140 MPGTPMVGLNDDR-------FGERFF-SLANAYDAEYRALLQKVAKEEGFPLTEG-VFVS 190
             G       +         FG+ F   L    +   R  L   A+ +G  L  G   V 
Sbjct: 115 TKGIRPASFFEGTSIVAHAMFGDPFSGKLVKWLEERVRKALD--AEGKGAKLFTGKCIVC 172

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
             GP F T AE  M +  GGD++ MSV+PE   AR  +L    ++  T+      D    
Sbjct: 173 MEGPQFSTRAESLMYRQWGGDLINMSVLPEAKLAREAELSYALIATATDY-----DSWRD 227

Query: 251 HAQTLAAAELSK 262
            ++++ AA++ K
Sbjct: 228 QSESVTAADVFK 239


>UniRef50_UPI000038263C COG0005: Purine nucleoside phosphorylase n=1 Tax=Magnetospirillum
           magnetotacticum MS-1 RepID=UPI000038263C
          Length = 162

 Score = 57.8 bits (138), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 39/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)

Query: 28  VAFILGSGLGALADQIENAVA-ISYEKLPGFPVSTVHGHAG-------ELVLGHLQGVPV 79
           +A +LGSG G  A+ +   VA +   ++PGF    V GH         E   G ++    
Sbjct: 40  MALVLGSGWGGAAELLGEVVAEVPTHEIPGFSAPAVAGHLSVTRSIRVERADGSVR--HA 97

Query: 80  VCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHI 137
           + +  R H YEG+G+  +   +RT    G E L  TN  G L  E GAG+ V L  H+
Sbjct: 98  LVLGSRTHLYEGKGVRAVVHGVRTAAATGAETLILTNGCGGLNQEWGAGTPVLLSXHM 155


>UniRef50_B4CZS2 Methylthioadenosine phosphorylase n=1 Tax=Chthoniobacter flavus
           Ellin428 RepID=B4CZS2_9BACT
          Length = 288

 Score = 57.0 bits (136), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 59/220 (26%), Positives = 90/220 (40%), Gaps = 19/220 (8%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM--K 83
           P +  I GSGL  + D + N    + E   G P   + G       G L G  V  +   
Sbjct: 4   PAIGIIGGSGLYQI-DGVTNVTEHTIETPFGAPSDVIVG-------GQLGGRQVYFLPRH 55

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           GRGH      +    + +   + L    L C  A GSL+ +     +V      +     
Sbjct: 56  GRGHRILPHELNHRAN-LYALRSLNVRWLLCVTAVGSLQEQYAPRHIVLPSQFFDRTSQG 114

Query: 144 PMVGLNDDRFGE---RFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETA 199
           P        FG       S A+   A  R L+   A+E G P+  G  +V+  GP F T 
Sbjct: 115 PAHTF----FGNGIAAHVSFADPTSAPLRQLIVNAARELGLPVHNGGTYVNMDGPAFSTR 170

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
           AE    + +G DV+GM+ + E+  AR  ++ V  ++ IT+
Sbjct: 171 AESETHRKLGFDVIGMTNLGEIRLAREAEIAVATMAMITD 210


>UniRef50_D1A6L7 Methylthioadenosine phosphorylase n=16 Tax=Actinomycetales
           RepID=D1A6L7_THECD
          Length = 279

 Score = 56.6 bits (135), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 57/225 (25%), Positives = 88/225 (39%), Gaps = 16/225 (7%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS--TVHGHAGELVLGHLQGVPVVCM 82
           T  +  I GSG  +  D IE     +    P  P++  TV G     +  H         
Sbjct: 15  TATIGVIGGSGFYSFLDDIEEVRLDTPYGPPSDPIAVGTVAGRTVAFIPRH--------- 65

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            GR H Y    +    + +   + LG   +   +A GSL P+ G G+L      ++   G
Sbjct: 66  -GRDHRYPPHKIPYRAN-LWALRSLGVRQVLAPSAVGSLVPQYGPGTLAVPDQLVDRTYG 123

Query: 143 TPMVGLNDDRFGERFFSLANAY-DAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAE 201
              V    +  G    S A+ Y     R +L    K +  P+  G  V   GP F T AE
Sbjct: 124 --RVQTFYEEGGAIHVSFADPYCPVGRRVVLDTARKADWEPVDGGTLVVIEGPRFSTRAE 181

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD 246
            +     G  +VGM+  PE + AR   L    +  +T++  G+ +
Sbjct: 182 SQWYAAQGWTLVGMTGHPEAVLARELALCYTPICLVTDLDAGIEE 226


>UniRef50_Q0BRD3 5'-methylthioadenosine phosphorylase n=113 Tax=cellular organisms
           RepID=Q0BRD3_GRABC
          Length = 319

 Score = 56.6 bits (135), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 57/220 (25%), Positives = 92/220 (41%), Gaps = 20/220 (9%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM--K 83
           P +  I GSGL  + D +EN      E   G P       + +L+ G L GV  V +   
Sbjct: 31  PVIGIIGGSGLYDI-DGLENKEWRRVETPWGLP-------SDDLLFGTLDGVQCVFLPRH 82

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           GRGH      +    + I   K  GC  +   +A GSL+ ++  G  V +   I+     
Sbjct: 83  GRGHRLSPSHLNYRAN-IDAMKRAGCTDILSLSAVGSLKKKLPPGHFVIVDQFIDRS--- 138

Query: 144 PMVGLNDDRFGE---RFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETA 199
                    FG+      S+A+        ++++ AK    P   G  ++   GP F T 
Sbjct: 139 --FAREKSFFGDGCVAHVSVADPVCPRIGDVVEQAAKRLSLPYARGGTYLVMEGPQFSTR 196

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
           AE  + +  G  V+GM+ +PE   AR  ++    V+ +T+
Sbjct: 197 AESELYRSWGCSVIGMTNMPEAKLAREAEMCYATVAMVTD 236


>UniRef50_B1GZW8 S-methyl-5'-thioadenosine phosphorylase n=1 Tax=uncultured Termite
           group 1 bacterium phylotype Rs-D17 RepID=B1GZW8_UNCTG
          Length = 293

 Score = 56.2 bits (134), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 58/221 (26%), Positives = 94/221 (42%), Gaps = 22/221 (9%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM--KG 84
           ++AFI GSGL  + D IEN V    +   G P       + +++ G +  +    +   G
Sbjct: 9   KIAFIGGSGLYQI-DGIENIVEKDIDTPFGRP-------SDKIITGVINRINCAFLPRHG 60

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           RGH      +    + I   K LG E +    A GSL+ E+     V      +      
Sbjct: 61  RGHILNPSEINQRAN-IYALKSLGTEQIVSFTACGSLKEEIKPKDFVIPDQVFDRTKNRS 119

Query: 145 MVGLNDDRFGER----FFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETA 199
           +       F E+      S+A  +  E R+L+++   E G      G +V   GP F T 
Sbjct: 120 LT------FFEKGIVAHVSMAYPFCNEIRSLIRQTVYEIGIKYHFCGTYVCIEGPQFSTK 173

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
           AE ++ +  G  VVGM++ PE   AR  ++    +S +T+ 
Sbjct: 174 AESQINRQSGFSVVGMTLFPEAKLAREAEICYANISLVTDF 214


>UniRef50_Q07938 Multicopy enhancer of UAS2 n=12 Tax=Saccharomycetaceae
           RepID=MEU1_YEAST
          Length = 337

 Score = 56.2 bits (134), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 39/136 (28%), Positives = 59/136 (43%), Gaps = 10/136 (7%)

Query: 104 FKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDR-------FGER 156
            K L C+ +   +A GSL+P +     V  +  I+   G       +D        FG+ 
Sbjct: 109 LKNLNCKAVLSFSAVGSLQPHIKPRDFVLPQQIIDRTKGIRHSSYFNDEGLVGHVGFGQP 168

Query: 157 FFSLANAYDAEYRALLQKVAKEEGFPL---TEGVFVSYPGPNFETAAEIRMMQIIGGDVV 213
           F      Y  +++  +     EE   L    +   V   GP F T AE +M ++ GG V+
Sbjct: 169 FSQKFAEYIYQFKNEITNPESEEPCHLHYDKDMTVVCMEGPQFSTRAESKMYRMFGGHVI 228

Query: 214 GMSVVPEVISARHCDL 229
            MSV+PE   AR C+L
Sbjct: 229 NMSVIPEAKLARECEL 244


>UniRef50_B5JG81 Phosphorylases family 2 n=1 Tax=Verrucomicrobiae bacterium DG1235
           RepID=B5JG81_9BACT
          Length = 230

 Score = 55.5 bits (132), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 42/145 (28%), Positives = 70/145 (48%), Gaps = 12/145 (8%)

Query: 107 LGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDA 166
           LG   +   ++ GS  P++  GSLV+  D+++  P T +    DDR       L+N +  
Sbjct: 67  LGIRSVVTLSSVGSADPDLPPGSLVSCSDYMSFAPKTFI----DDRTSAFAPVLSNPH-- 120

Query: 167 EYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISAR 225
                L  +A      +  + V++   GP FET AE+R ++ +G DVVGM+   E     
Sbjct: 121 -----LAGIASRSSVEIVRDKVYMQTRGPRFETKAEVRAIRTLGADVVGMTFGNEADLLL 175

Query: 226 HCDLKVVAVSAITNMAEGLSDVKLS 250
              ++V A   + N A G++  +LS
Sbjct: 176 ERGIEVTAFCMVDNFAHGVNSAELS 200


>UniRef50_Q1CZV1 Phosphorylase, family 2 n=5 Tax=Myxococcaceae RepID=Q1CZV1_MYXXD
          Length = 295

 Score = 55.1 bits (131), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 50/178 (28%), Positives = 72/178 (40%), Gaps = 7/178 (3%)

Query: 65  HAGELVLGHLQGVPV--VCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLR 122
           HAG +V   L GV V  V   G GH Y         + +   K+LG   +  T   GSLR
Sbjct: 35  HAGPIVTTELDGVSVAYVARHGTGHVYNATRAPYRAN-MYALKVLGVTHVLATGTVGSLR 93

Query: 123 PEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP 182
             +    L      I+     P    +D         L N +    R +L+      G  
Sbjct: 94  EHIHPLHLALPDQVIDRTYRRPCTFYDDVAV---HVDLGNPFCGTLRQVLEHARDPLGPT 150

Query: 183 L-TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
           +  E  +V   GP+  T AE  + +  GGD+VGM+ +PE   AR  +L    V+  T+
Sbjct: 151 VHAEATYVCIEGPSLSTRAESMLYRTWGGDLVGMTGMPEARLAREAELHYAMVALPTD 208


>UniRef50_A4AL37 5'-methylthioadenosine phosphorylase n=3 Tax=Actinobacteria (class)
           RepID=A4AL37_9ACTN
          Length = 267

 Score = 55.1 bits (131), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 43/170 (25%), Positives = 76/170 (44%), Gaps = 4/170 (2%)

Query: 107 LGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDA 166
           +G   +  T A G++ P+   GSLV    +I+   G        DR   +  + ++ +  
Sbjct: 78  IGVRAIVSTAAVGAVHPDFPVGSLVLPDQYIDRTQGRAATFY--DRESVQHLASSDPFCP 135

Query: 167 EYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARH 226
              AL      +E   + +G  V   GP F T AE +  + +GG +V M++ PEV  A  
Sbjct: 136 SLHALAVAATGDEA--IAQGTVVVIQGPRFSTRAESQWFRSMGGHLVNMTLYPEVPLASE 193

Query: 227 CDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
            ++  + V+ IT+    +SD +LS     A  + ++   I +I   +  I
Sbjct: 194 LNIGTINVAYITDNDATVSDEQLSAELVFARLKEAQPRIIRVIEKIIATI 243


>UniRef50_D1J9Q0 Putative uncharacterized protein n=2 Tax=uncultured archaeon
           RepID=D1J9Q0_9ARCH
          Length = 245

 Score = 55.1 bits (131), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 47/176 (26%), Positives = 79/176 (44%), Gaps = 10/176 (5%)

Query: 103 TFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLAN 162
           +FKLL  E +    + GSL+  +   SLV   D+I  +   P V      + +    +  
Sbjct: 77  SFKLLDVEKIIGATSVGSLKRAITPRSLVVPHDYI-CLYNIPTV------YDDEIVHVTP 129

Query: 163 AYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEV 221
             D   R+ + +VA E    + E GV+     P  ET AEIR M+    DVVGM++  E 
Sbjct: 130 GLDDGLRSTIIEVANELDMEIFEQGVYFQTVAPRLETKAEIRFMRNYA-DVVGMNMASEA 188

Query: 222 ISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQTLAAAELSKQNFINLICGFLRKI 276
             A    L+   +S + N A G+ + + L + + +  A  S+ +   ++   +  I
Sbjct: 189 TLAMELGLRYADISTVDNYAHGIIEEEVLDYKKIVEDASKSRVDLEKVLIKLIEVI 244


>UniRef50_D1YZM1 5'-methylthioadenosine phosphorylase n=1 Tax=Methanocella
           paludicola SANAE RepID=D1YZM1_METPS
          Length = 281

 Score = 54.7 bits (130), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 51/195 (26%), Positives = 87/195 (44%), Gaps = 28/195 (14%)

Query: 59  VSTVHGHAGE-LVLGHLQGVPVVCMK--GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCT 115
           V T  G  G+  ++G + G+  V +   GRGH Y    +    + I   K LG   +   
Sbjct: 26  VRTPFGTPGDSFIVGSMNGIEAVFLSRHGRGHKYSPTDLNYRAN-IYGMKKLGVTHIISV 84

Query: 116 NAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGER---FF--------SLANAY 164
           +A GSL+  +    +V + D +             DR  +R   +F        S A+ +
Sbjct: 85  SAVGSLKESLKPLDIV-IPDQVY------------DRTTKRVSTYFEGGIVAHISFADPF 131

Query: 165 DAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISA 224
             +   +L + AKE+      G ++   GP F T AE R+ + +G DV+GM+ +PE   A
Sbjct: 132 CRKLSDILYETAKEKYRVHNGGTYLCMEGPQFSTKAESRIYRKLGFDVIGMTALPEAKLA 191

Query: 225 RHCDLKVVAVSAITN 239
           R  ++    ++ IT+
Sbjct: 192 REAEICFAILATITD 206


>UniRef50_D2V2R7 5'-methylthioadenosine phosphorylase n=1 Tax=Naegleria gruberi
           RepID=D2V2R7_NAEGR
          Length = 299

 Score = 54.7 bits (130), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 59/227 (25%), Positives = 101/227 (44%), Gaps = 26/227 (11%)

Query: 26  PRV--AFILGSGLGALADQIENAVAISYEKLP-GFPVSTVHGHAGELVLGHLQGVPV--V 80
           PRV  AFI G+GL   A+ +EN + +   + P G P S +       V+G + G+ V  +
Sbjct: 10  PRVDLAFIGGTGLSK-AEGLENVITVEPFETPFGKPSSPI-------VIGTINGLTVAFL 61

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
           C  G  H  +   +    + I   K LG   L    A GSL+ E+     V +   I+  
Sbjct: 62  CRHGLSHSVQPTDVPYRAN-IFALKSLGANNLVSFGAVGSLQEELAPKHFVVVDQFIDRT 120

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAE------YRALLQKVAKEEGFPLTE--GVFVSYP 192
                   +++ F +R   +A+    E       + ++   ++ E  P T   G +V   
Sbjct: 121 ----KFRQSENTFYDREGLVAHVSFGEPTCKTLSQLVVDSCSRIETIPKTHATGTYVCME 176

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
           GP F + AE +M ++ GG ++GM+ + E   AR  ++    V  +T+
Sbjct: 177 GPCFSSRAESKMYRMWGGSIIGMTCLQEAKLAREAEMAFACVGMVTD 223


>UniRef50_B3PJG7 Methylthioadenosine phosphorylase n=1 Tax=Cellvibrio japonicus
           Ueda107 RepID=B3PJG7_CELJU
          Length = 308

 Score = 53.9 bits (128), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 53/220 (24%), Positives = 88/220 (40%), Gaps = 37/220 (16%)

Query: 57  FPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTN 116
           F + T  G + ++      G+P   +   G     +    + D       LG E      
Sbjct: 59  FTLETTLGTSPKIYYAEWDGIPFYYVHNHGDGQWQQTWVALYD-------LGVEEAIGGA 111

Query: 117 AAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDR---FGERFFSLANA---------Y 164
            AG++ P +     +   D         ++ +N DR   F ++ +   NA          
Sbjct: 112 TAGAINPSMKVYDYIIPHD---------LIDMNIDRPLGFPKQVYRDPNAIPLPRLTPAM 162

Query: 165 DAEYRALLQKVAKE--------EGFPL-TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGM 215
           D + R +L +  ++        + F +  +GV V   G  FET AEI+M    GGD+V M
Sbjct: 163 DTDLRQILLEQTRKAIKADKRYKSFKVHDKGVIVQARGGRFETVAEIKMFGQWGGDLVTM 222

Query: 216 SVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL 255
           SV  E++ AR   +    V  I+N AEG+ +   S  + L
Sbjct: 223 SVGTEIVYARQLGINYATVVVISNPAEGVGEWDFSLMKEL 262


>UniRef50_C4Q4X0 Methylthioadenosine phosphorylase, putative n=1 Tax=Schistosoma
           mansoni RepID=C4Q4X0_SCHMA
          Length = 314

 Score = 53.5 bits (127), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 44/176 (25%), Positives = 73/176 (41%), Gaps = 21/176 (11%)

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG- 142
           G+GH      +    + +   K LGC  +  TNA GSL+ ++  G  V L   ++   G 
Sbjct: 56  GKGHLIPPSEVNYRAN-VWALKDLGCTHILATNACGSLQEDLVPGDFVVLNQFMDKTWGR 114

Query: 143 -TPMVGLNDDRF-GERFFSLANAYDAEYRALLQKVAKEEGFPL----------------- 183
                G   D   G     +A  +    R +L + A+ +   +                 
Sbjct: 115 ENTFYGSKPDSLKGVLHMPMAEPFCERTRQILIQAARNKSINVYDKKTMDKSACIHPCVH 174

Query: 184 TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
            EG  V+  GP F T  E  + + +G D+V M++VPEV  AR   L   +++ +T+
Sbjct: 175 AEGSAVTINGPRFSTRCESFIHKAMGLDIVNMTLVPEVSLAREAGLSYASIAIVTD 230


>UniRef50_A9A3N5 Methylthioadenosine phosphorylase n=4 Tax=Archaea
           RepID=A9A3N5_NITMS
          Length = 263

 Score = 53.1 bits (126), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 37/144 (25%), Positives = 64/144 (44%), Gaps = 11/144 (7%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGER---- 156
           I  FK LG   +   +A GSL+ E+  G  V     ++           D  F E     
Sbjct: 73  IWAFKELGVTRIIAPSAVGSLKEELAPGHFVLPTQFLD------FTKSRDGSFSEDGRVI 126

Query: 157 FFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGM 215
             S+A+ +  E ++ + +V       +  +  +V   GP F T AE +  +  G D++GM
Sbjct: 127 HISVADPFCPELQSSITEVTDSLDMNIHKDCTYVCIEGPRFSTKAESKFYRTTGADIIGM 186

Query: 216 SVVPEVISARHCDLKVVAVSAITN 239
           ++VPE   AR   +   ++S +T+
Sbjct: 187 TLVPECQLAREAQICYASISTVTD 210


>UniRef50_A9GWF6 5'-methyl-5-thioadenosine phosphorylase n=1 Tax=Sorangium
           cellulosum 'So ce 56' RepID=A9GWF6_SORC5
          Length = 295

 Score = 52.8 bits (125), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 63/238 (26%), Positives = 97/238 (40%), Gaps = 28/238 (11%)

Query: 52  EKLPGFPVSTVHGHAGELVL-GHLQG----VPVVCMKGRGHFYEGRGMTIMTDAIRTFKL 106
           E +    VST  G   ++VL G ++G    V  +   GRGH +    +    + I   K+
Sbjct: 25  EDVEEVSVSTPFGLPSDVVLRGQVKGGDATVLFLPRHGRGHRFSPSTINYRAN-ICALKM 83

Query: 107 LGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFS------L 160
           LG   +   +A GSLR ++  G LV +   I+          ++       F+      L
Sbjct: 84  LGATHVLSVSAVGSLREDIAPGDLVVVDQFIDFTKRRISTFFDEGLVAHVPFADPVCPIL 143

Query: 161 ANA-YDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVP 219
           A+A +DA   AL        G     G +V   GP F T AE RM +  G  V+GM+ +P
Sbjct: 144 ASAVHDA---ALATGARVHRG-----GTYVCIEGPQFSTRAESRMFRTFGAHVIGMTNLP 195

Query: 220 EVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           E   AR  +L    ++  T       D    H    A +  +    +N   G+ R +A
Sbjct: 196 EAKLAREAELPYATLALTT-------DFDCWHVSEEAVSVEAVIAVLNRNIGYARDVA 246


>UniRef50_A9BDU8 5'-methylthioadenosine phosphorylase n=13 Tax=Cyanobacteria
           RepID=A9BDU8_PROM4
          Length = 316

 Score = 52.8 bits (125), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 57/232 (24%), Positives = 105/232 (45%), Gaps = 20/232 (8%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM--KG 84
           R+  + GSGL ++ + +EN   I  +   G P       + +L LG L G+ VV +   G
Sbjct: 24  RLGVLGGSGLYSI-NNLENIKEIEIDTPYGKP-------SDKLRLGILGGMEVVFLARHG 75

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H +   G+    + I   + LG   +   +A GSL+ +V    +V     I+     P
Sbjct: 76  RHHTFTPTGIPYRAN-IWALRSLGVRWILAPSAVGSLQEQVRPLDMVVPDQFIDRTHQRP 134

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE---EGFPLTEG-VFVSYPGPNFETAA 200
           +   +D        ++A+ +      LL +  ++   EG  L  G ++++  GP F T A
Sbjct: 135 LTFFSDGAVAH--VTMADPFCPTLSRLLTEEGQKLMPEGRQLHRGGIYLAMEGPAFSTRA 192

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN---MAEGLSDVKL 249
           E ++ +  G  V+GM+   E   AR  ++   ++S +++     EG  +V +
Sbjct: 193 ESQLYRSWGCTVIGMTNHTEARLAREAEIAYASISMVSDYDCWHEGYGNVSV 244


>UniRef50_B7RUB3 Phosphorylases family 2 n=1 Tax=marine gamma proteobacterium
           HTCC2148 RepID=B7RUB3_9GAMM
          Length = 246

 Score = 52.8 bits (125), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 52/178 (29%), Positives = 72/178 (40%), Gaps = 7/178 (3%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERF-FS 159
           +   K L    L   NA G +   +  G LV + D I          ++    G      
Sbjct: 70  VWALKSLQVTDLVAINAVGGISAAMRPGRLV-IPDQIVDYTWGRAHTVDTGEVGTLLHVD 128

Query: 160 LANAYDAEYR-ALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVV 218
            ++ YD E R ALLQ    +       GV     GP  E+AAEIR M   G D+VGM+ +
Sbjct: 129 FSDPYDHELREALLQCAVAQNIAHEGAGVHGVMQGPRLESAAEIRRMAGDGCDLVGMTGM 188

Query: 219 PEVISARHCDLKVVAVSAITNMAEGLSDVKLS----HAQTLAAAELSKQNFINLICGF 272
           PE   AR   L   ++  + N A GL D  L+     A  L  A   +Q    L+  +
Sbjct: 189 PEASLARELGLAYASICMVVNAAAGLDDKPLTLAVMRANLLREAAAVRQLIAALVADY 246


>UniRef50_A0YHC5 Methylthioadenosine phosphorylase n=1 Tax=marine gamma
           proteobacterium HTCC2143 RepID=A0YHC5_9GAMM
          Length = 241

 Score = 52.8 bits (125), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 47/186 (25%), Positives = 79/186 (42%), Gaps = 3/186 (1%)

Query: 61  TVHGHAGELVLG-HLQGVPVVCMKGRGHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAA 118
           T +G     ++G  ++G+PV  +   G  +      +   A I  FK LG   L   NA 
Sbjct: 24  TPYGETSAAIIGSEIEGIPVCFLARHGDPHRIPPHKVNYRANIWAFKELGVSKLVAVNAV 83

Query: 119 GSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE 178
           G +  E+ AGSLV     ++   G      + +         +  + +  R L+   A  
Sbjct: 84  GGITSEMPAGSLVIPDQIVDYTYGRDHTFYDGNNNELEHIDFSFPFASGLRQLIVAAAAA 143

Query: 179 EGFPLTEGVFVSYP-GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAI 237
               + +G  +    GP  E+AAEI  M+  G ++VGM+ +PE   AR   +   ++  +
Sbjct: 144 SNINIIDGATLGVTQGPRLESAAEINRMESDGCELVGMTAMPEAALARELSIDYASICLV 203

Query: 238 TNMAEG 243
            N A G
Sbjct: 204 VNPAAG 209


>UniRef50_B9KZC3 Methylthioadenosine phosphorylase n=2 Tax=Bacteria
           RepID=B9KZC3_THERP
          Length = 289

 Score = 52.4 bits (124), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 53/210 (25%), Positives = 89/210 (42%), Gaps = 13/210 (6%)

Query: 33  GSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPV--VCMKGRGHFYE 90
           GSGL  +  ++ +   I+ E   G P  T+        LG L G+ V  +   GR H + 
Sbjct: 10  GSGLYRMP-ELTDVEEIAIETPFGRPSDTI-------TLGTLHGMRVAFIPRHGRAHQHS 61

Query: 91  GRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLND 150
              +    +     K LG + +   +A GSLR E+     V     ++     P     D
Sbjct: 62  PSNVPARAN-FWALKSLGVQWVVSVSAVGSLREEIAPLDFVVPDQVVDRTVRRPR-SFFD 119

Query: 151 DRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRMMQIIG 209
           +       +L   +  E R  L + A   G  + + G ++   GP F T AE  + +  G
Sbjct: 120 ESGLVVHVTLDEPFCPELRWALTQAAIAAGVRVHDRGTYICIEGPQFSTRAESNLYRSWG 179

Query: 210 GDVVGMSVVPEVISARHCDLKVVAVSAITN 239
            D++GM+ +PEV  AR  +L    ++ +T+
Sbjct: 180 LDIIGMTAMPEVRLAREAELCFALLALVTD 209


>UniRef50_B8P408 Predicted protein n=2 Tax=Agaricomycetes RepID=B8P408_POSPM
          Length = 329

 Score = 52.4 bits (124), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 70/256 (27%), Positives = 103/256 (40%), Gaps = 28/256 (10%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +  I GSGL  L D +     ++ E   GFP S +   A    L     V  +   G GH
Sbjct: 16  IGVIGGSGLYHL-DNLTFIKHVNPETPWGFPSSPITICA----LPSGTRVAFLARHGTGH 70

Query: 88  FYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG 147
                 +    + I   K LG   +   +A GSLR ++  G +V     I+   G     
Sbjct: 71  SIAPSAVPARAN-IAALKALGVRAVLAFSAVGSLREDIRPGDVVLPAQIIDRTKGVRPAS 129

Query: 148 LNDDR-------FGERFFS-LANAYDAEYRALLQ----KVAKEEGFP------LTEGVFV 189
             +         FG+ F + L    +   RA+L     +V +E G P        +   V
Sbjct: 130 FFEGTGVVAHAAFGDPFAARLVRWLEGRVRAVLAEEAARVQRETGRPDAGPRVHADKCVV 189

Query: 190 SYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDL---KVVAVSAITNMAEGLSD 246
              GP F T AE +M +  GGD++ MSV+PE   AR  +L     ++V A+   A    D
Sbjct: 190 CMEGPQFSTRAESQMYRAWGGDIINMSVLPEAKLAREAELLPPPSLSVYALIATATDY-D 248

Query: 247 VKLSHAQTLAAAELSK 262
               H   + AAE+ K
Sbjct: 249 SWRPHEDAVTAAEVFK 264


>UniRef50_C1SHM5 Purine nucleoside phosphorylase n=1 Tax=Denitrovibrio acetiphilus
           DSM 12809 RepID=C1SHM5_9BACT
          Length = 263

 Score = 52.4 bits (124), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/65 (41%), Positives = 35/65 (53%)

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           G +V   GP  ET  EI+     G D+VGM++ PE   AR  +L    +S ITN A G S
Sbjct: 154 GTYVCTNGPRMETKGEIKAFDRWGADLVGMTLFPECSLARERELCYANLSVITNYAAGTS 213

Query: 246 DVKLS 250
             KL+
Sbjct: 214 STKLT 218


>UniRef50_B8KGW0 Purine phosphorylase, family 2 n=1 Tax=gamma proteobacterium NOR5-3
           RepID=B8KGW0_9GAMM
          Length = 249

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 44/177 (24%), Positives = 71/177 (40%), Gaps = 3/177 (1%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERF-FS 159
           +   + LG   +   NA G++   +  G LV     I+   G      +D   GE     
Sbjct: 70  VWALRELGVTRILAANAVGAISAGMAPGKLVVPHQLIDYTWGREH-SFDDGSSGELLHVD 128

Query: 160 LANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVV 218
               YD   R+ +   A+  G P ++  V     GP  ETAAE++     G D++GM+ +
Sbjct: 129 FTQPYDGVLRSEIISAAESAGVPHSDTAVLGVVQGPRLETAAEVQRFAADGCDLLGMTGM 188

Query: 219 PEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRK 275
           PE   AR   +   A+  + N A G+    +S              F  L+  F+R+
Sbjct: 189 PEAALARELGIPYAAICMVVNAAAGVGAEPISMEAIRNTLLEETALFGALVGAFVRR 245


>UniRef50_Q9RKG9 Putative phosphorylase n=1 Tax=Streptomyces coelicolor
           RepID=Q9RKG9_STRCO
          Length = 262

 Score = 50.8 bits (120), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 40/133 (30%), Positives = 60/133 (45%), Gaps = 6/133 (4%)

Query: 119 GSLRPEVGAGSLVALKD---HINTMP-GTPMVGLNDDR-FGERFFSLANAYDAEYRALLQ 173
           GSL P+V  GSLV   D     N +P GTP    +     G   +     +    R  L 
Sbjct: 85  GSLEPDVRPGSLVVFDDLYFPANRLPDGTPCTWYDTPGGAGRGHWIFDRPFSEPLRQALI 144

Query: 174 KVAKEEGFPL-TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVV 232
             A + G P+ T+GV+    GP F T  E+  +   G   +  +  PEV+ A   +L +V
Sbjct: 145 TAADQTGVPVATQGVYGHVDGPRFNTRPEVAALAAAGVSAISQTAGPEVVLAGEAELPMV 204

Query: 233 AVSAITNMAEGLS 245
            V  +T+ A G++
Sbjct: 205 LVGFVTDYANGVA 217


>UniRef50_B5EMB0 Methylthioadenosine phosphorylase n=15 Tax=Proteobacteria
           RepID=B5EMB0_ACIF5
          Length = 270

 Score = 50.8 bits (120), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 29/75 (38%), Positives = 39/75 (52%)

Query: 171 LLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLK 230
           LLQ     +   +  G + +  GP  ET AEIR ++  GGDVVGM+  PE + AR   L 
Sbjct: 141 LLQAAGSADIVVIDGGTYAATQGPRLETIAEIRRIERDGGDVVGMTGAPEAVLAREIGLC 200

Query: 231 VVAVSAITNMAEGLS 245
              +S + N A G S
Sbjct: 201 YAPLSLVVNPAAGKS 215


>UniRef50_A3EWJ6 Methylthioadenosine phosphorylase n=2 Tax=Leptospirillum sp. Group
           II RepID=A3EWJ6_9BACT
          Length = 300

 Score = 50.1 bits (118), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 58/216 (26%), Positives = 93/216 (43%), Gaps = 16/216 (7%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGE-LVLGHLQGVPVVCMK--G 84
           V  I GSGL     Q+E  + I  E++    V T  G + +  ++G +  +PVV +   G
Sbjct: 18  VGIIGGSGL----YQME-GLTIEEERV----VETPWGVSSDPYLIGKVGTLPVVFLSRHG 68

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           +GH Y    +    + +   K LG   +   +A GSL+ E+  G +V + D I+     P
Sbjct: 69  KGHRYLPSEINYRAN-LAGLKSLGVSRVLSVSAVGSLKEEIAPGDMVLVDDFIDLTRQRP 127

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIR 203
           M    +   G   +      D  + A      +  G P   G  ++   GP F T AE R
Sbjct: 128 MSFYGNGAVGHTPYGRPVCSDL-FEAF-SGACEHLGLPTHRGGTYICMEGPAFSTRAESR 185

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
           + +  G DV+GM+   E   AR   L    ++  T+
Sbjct: 186 LYRQWGADVIGMTNGTEARLAREIGLCYATLALATD 221


>UniRef50_C9ZU87 Methylthioadenosine phosphorylase, putative n=8
           Tax=Trypanosomatidae RepID=C9ZU87_TRYBG
          Length = 309

 Score = 50.1 bits (118), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 50/185 (27%), Positives = 74/185 (40%), Gaps = 25/185 (13%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFS- 159
           I   KLLG + L   NA GSL  E   G +V +   I+        G     FGE   + 
Sbjct: 79  IYALKLLGVKYLIGVNAVGSLDAEYQPGDMVLVDQLIDRT-----TGRRTTFFGEGIVAH 133

Query: 160 --LANAYDAEYRALLQKVAKEEGFPLTEGV-------------FVSYPGPNFETAAEIRM 204
              A    A +R L      +    LT  V              V+  GP F T AE  +
Sbjct: 134 VDYAYPLSANFRKLAHDTLTKAMGKLTTAVSGGKPWKLHNGATLVTMSGPQFSTRAESLI 193

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD---VKLSHAQTLAAAELS 261
            + + G ++GM+   E   AR  ++  + V+A+T+M +  SD   V     + + AA + 
Sbjct: 194 NKSLNGHLIGMTTSTESKLAREAEMAYLVVAAVTDM-DAWSDAPHVDAESVRKVMAANVE 252

Query: 262 KQNFI 266
           K   I
Sbjct: 253 KVQLI 257


>UniRef50_A4U101 Purine phosphorylase, family 2 n=4 Tax=Proteobacteria
           RepID=A4U101_9PROT
          Length = 291

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 47/184 (25%), Positives = 81/184 (44%), Gaps = 24/184 (13%)

Query: 68  ELVLGHLQGVPVVCM--KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
           +L+ G L G  +V +   GRGH      +    + I   K  G   +   +A GSL+ E+
Sbjct: 38  DLLFGELNGQQLVFLPRHGRGHRIPPSELNYRAN-IDALKRAGVTEIVSVSAVGSLKEEL 96

Query: 126 GAGSLVALKDHIN-TMPGTPMVGLNDDRFGERFF--------SLANAYDAEYRALLQKVA 176
             G+ V +   I+ T   T           + FF        S+A+        ++++ A
Sbjct: 97  PPGTFVIVDQFIDRTFART-----------KSFFETGLVAHVSMAHPVCGRLGDIIEQAA 145

Query: 177 KEEGF-PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVS 235
           K+ G   +  G ++   GP F T AE  + +  G DV+GM+ +PE   AR  ++    V+
Sbjct: 146 KDAGIVAVRGGTYLVMEGPQFSTQAESNLYRQWGCDVIGMTNMPEAKLAREAEMCYATVA 205

Query: 236 AITN 239
            +T+
Sbjct: 206 MVTD 209


>UniRef50_D1C2Y0 Methylthioadenosine phosphorylase n=2 Tax=Bacteria
           RepID=D1C2Y0_SPHTD
          Length = 295

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 45/166 (27%), Positives = 69/166 (41%), Gaps = 4/166 (2%)

Query: 66  AGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPE 124
           +  L +G L GV V  +   G  +E     +   A     K +G   +   +A GSLR +
Sbjct: 39  SAPLAIGTLAGVRVAFLPRHGRHHEYHPSRVPARANFWALKAVGVRRVISVSAVGSLRED 98

Query: 125 VGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL- 183
           +    LV     ++     P      D        LA+ +  E RA L   A      + 
Sbjct: 99  IHPLDLVVPDQVVDRTVDRPRTFF--DTAPVVHVELADPFCPEVRAALITAANSVAPRVH 156

Query: 184 TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDL 229
           + G ++   GP F T AE  + +  G D+VGM+ +PEV  AR  +L
Sbjct: 157 SSGTYLCIEGPQFSTRAESELHRRWGMDLVGMTAMPEVRLAREAEL 202


>UniRef50_Q1H1A2 Methylthioadenosine phosphorylase n=3 Tax=Bacteria
           RepID=Q1H1A2_METFK
          Length = 248

 Score = 48.5 bits (114), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 55/220 (25%), Positives = 89/220 (40%), Gaps = 14/220 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH-AGELVLGHLQGVPVVCMKGRG 86
           +  I G+GL  LA+     + I   ++    V T +G  +G L  G + G  V+ +   G
Sbjct: 2   LGIIGGTGLTKLAN-----LKIKRRQI----VRTPYGEPSGPLTYGDICGYEVIFLPRHG 52

Query: 87  HFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHI-NTMPGTP 144
           H +      +   A I      G   +    + G + P +  G ++AL D I +   G  
Sbjct: 53  HGHTIPPHIVNYRANIWALHAEGVRDIVSVASVGGIHPRLDPG-VIALPDQIIDYTHGRK 111

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIR 203
               +      +       Y    R L  + A      + +G V+    GP  ETAAEI 
Sbjct: 112 NTYYDGGDLPVKHIDFTMPYSDRLRNLCLEAATNISESIIDGGVYACVQGPRLETAAEIN 171

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG 243
            ++  G  +VGM+ +PE   AR  D+   A+  + N A G
Sbjct: 172 RLERDGATMVGMTGMPEAALARELDMHYAAICPVANHAAG 211


>UniRef50_Q0F2U5 Purine nucleoside phosphorylase n=1 Tax=Mariprofundus ferrooxydans
           PV-1 RepID=Q0F2U5_9PROT
          Length = 290

 Score = 47.8 bits (112), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 55/224 (24%), Positives = 89/224 (39%), Gaps = 30/224 (13%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH-AGELVLGHLQGVPVVCM--K 83
           R   I GSGL  +A           E +    + T +G  + ELVL  +    VV +   
Sbjct: 8   RTGIIGGSGLYNIA---------GVEIIDTLTIDTPYGAPSDELVLARIGDQEVVFLPRH 58

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHI------ 137
           GR H      +    + +   KL G   +   +A GSLR  +  G  V +   +      
Sbjct: 59  GRNHSIPPHKINYRAN-VYAMKLAGVNRIISISAVGSLRKHIHPGEFVLVDQFVDRTHSR 117

Query: 138 -NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPN 195
            NT    P+V            S+A+    + R+ L++     G     G  ++   GP 
Sbjct: 118 ENTFFDGPIVA---------HVSIADPVCNQLRSALEQACLASGITTHNGGRYLVMQGPQ 168

Query: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
           F + AE  + +  G DV+GM+ +PE   AR  ++    V+  T+
Sbjct: 169 FSSRAESELYRSWGMDVIGMTNMPEAKLAREAEICYATVAMCTD 212


>UniRef50_Q67R93 Methylthioadenosine phosphorylase n=1 Tax=Symbiobacterium
           thermophilum RepID=Q67R93_SYMTH
          Length = 265

 Score = 47.8 bits (112), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 55/214 (25%), Positives = 85/214 (39%), Gaps = 36/214 (16%)

Query: 59  VSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGR-GMTI----MTDAIRTFKLLGCELLF 113
           V T  G AG   +  + G PV  +   G   EGR G+T         +   + LG   + 
Sbjct: 26  VETPFGPAGPFRIFAVAGRPVAFLSRHGG--EGRLGVTPPFINYRANVWAARALGARRVL 83

Query: 114 CTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFF--------------- 158
             N+AGS+   +  GSL  + D I+     P      D FG                   
Sbjct: 84  SWNSAGSMVRALPPGSLAVVSDLIDWTRRRP------DSFGAAARDPAVRDTVVRHPAPP 137

Query: 159 -------SLANAYDAEYRA-LLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGG 210
                  + A  +D + RA L+Q  A          V+ +  G   ET AEI ++   G 
Sbjct: 138 AGHATGPAYAGLFDPDLRARLVQAAAACGHRAAPRAVYAATEGARLETRAEIALLAQAGA 197

Query: 211 DVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL 244
           ++VGM++ PEV  AR   +   ++  ++N A G+
Sbjct: 198 ELVGMTLAPEVFLARELGMAYGSICWVSNYATGV 231


>UniRef50_C6HVW5 Methylthioadenosine phosphorylase n=1 Tax=Leptospirillum
           ferrodiazotrophum RepID=C6HVW5_9BACT
          Length = 307

 Score = 47.0 bits (110), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 59/218 (27%), Positives = 85/218 (38%), Gaps = 20/218 (9%)

Query: 28  VAFILGSGL---GALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK- 83
           +  I GSGL     L+D +   V   + + P  P  T          G L GVPVV +  
Sbjct: 15  IGVIGGSGLYQLKGLSDLVPTVVETPWGQ-PSDPYMT----------GSLGGVPVVFLSR 63

Query: 84  -GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            G GH Y   G       I  F  LG + +   +A GSLR ++  G +V +   I+   G
Sbjct: 64  HGSGHRYL-PGEVNYRANIAGFVALGVKRILSVSAVGSLREDIVPGDMVVIDQFIDGTRG 122

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAE 201
            P         G   F  A+    +    L    +  G     +G +    GP F T AE
Sbjct: 123 RPSTFYGQGAVGHTAF--AHPICPDLAQTLIGACRTAGVRHHVKGTYYCMEGPAFSTQAE 180

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
             + +  G  V+GM+ V E   AR   L    ++  T+
Sbjct: 181 SFLYRQFGAHVIGMTNVTEARLAREAGLCYATLALSTD 218


>UniRef50_B0TI52 Purine nucleoside phosphorylase n=8 Tax=Clostridia
           RepID=B0TI52_HELMI
          Length = 304

 Score = 47.0 bits (110), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 33/57 (57%)

Query: 188 FVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL 244
           +V   G +FE+ AE+R  ++ GGDV+G SV PEV  AR        +  + N AEG+
Sbjct: 189 YVVTDGRHFESPAEVRFFRMAGGDVIGQSVAPEVYLAREIGACYARLELVVNYAEGV 245


>UniRef50_A2SSB6 Methylthioadenosine phosphorylase n=2 Tax=Methanomicrobiales
           RepID=A2SSB6_METLZ
          Length = 223

 Score = 47.0 bits (110), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 50/223 (22%), Positives = 84/223 (37%), Gaps = 28/223 (12%)

Query: 58  PVSTVHGHAGELVL--GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCT 115
           P  +V  H G +V    H    P   +  R H                 K+LG + L   
Sbjct: 26  PFGSVQAHVGRIVFISRHQNDTPPHRVNHRAHLA-------------AMKILGVDKLIVI 72

Query: 116 NAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKV 175
            + GS+  ++  GS+V   D  +     P +  ND       + +  + +   R  L ++
Sbjct: 73  GSTGSMHDDLPPGSIVIPDDSFSPW-DIPSLHDND------IYHIPPSINPGLREELVRI 125

Query: 176 AKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVS 235
             E       G +    GP FET AEI        DVVGM+   E+  A    +   A+ 
Sbjct: 126 VPEA----KPGTYFQTLGPRFETRAEIACFAG-DTDVVGMTAASELTLANELGIPCAALC 180

Query: 236 AITNMAEGLSDVKL-SHAQTLAAAELSKQNFINLICGFLRKIA 277
            + N A G+       + + +A A  + +   ++I   + K+A
Sbjct: 181 TVDNYANGIGGASAPEYDEIVAIARRNGERITDIITKIVEKLA 223


>UniRef50_P74469 Sll0135 protein n=67 Tax=cellular organisms RepID=P74469_SYNY3
          Length = 326

 Score = 47.0 bits (110), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 59/223 (26%), Positives = 94/223 (42%), Gaps = 27/223 (12%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPV--VCMKGR 85
           +  I GSGL  + + ++N   ++ +   G P       +   ++G L GV V  +   GR
Sbjct: 38  IGIIGGSGLYQM-EALKNVEEVTLDTPFGAP-------SDSFIVGELAGVRVAFLARHGR 89

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA-------LKDHIN 138
           GH      +    + I   K LG + L   +A GSL+ E     +V         +  I+
Sbjct: 90  GHHLLPSEIPFRAN-IHGMKQLGVKYLISASAVGSLQAEAKPLDMVVPDQFIDRTRQRIS 148

Query: 139 TMPGTPMVGLNDDRFGERFF-SLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNF 196
           T  G  +V      FG      LA         L     + EG  L + G +VS  GP F
Sbjct: 149 TFFGEGIVA--HIGFGNPICPQLAQCLSTAIAGL-----ELEGVTLHDRGTYVSMEGPAF 201

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
            T AE  + +  GG V+GM+ +PE   AR  ++    ++ +T+
Sbjct: 202 STIAESNLYRSWGGTVIGMTNLPEAKLAREAEIAYATLALVTD 244


>UniRef50_Q87BR7 Probable S-methyl-5'-thioadenosine phosphorylase n=16 Tax=Bacteria
           RepID=MTNP_XYLFT
          Length = 248

 Score = 46.6 bits (109), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 40/149 (26%), Positives = 60/149 (40%), Gaps = 5/149 (3%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFF-- 158
           I   + LG   +   N  G +    G  +LV     I+   G   V    +  G      
Sbjct: 72  IAALQQLGVSRVLALNTVGGINEAFGPRTLVCPDQLIDYTWGR--VSTFCEEVGSEVLHV 129

Query: 159 SLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSV 217
              + Y    R  L + A++    L E G +    GP  ET AEI  ++  G D+VGM+ 
Sbjct: 130 DFGHPYSPLLRGCLLRAARDVDVSLVEYGCYGVTQGPRLETIAEIDRLRRDGCDLVGMTG 189

Query: 218 VPEVISARHCDLKVVAVSAITNMAEGLSD 246
           +PE   AR   L+   +  ++N A G  D
Sbjct: 190 MPEAALAREKGLEYACLGIVSNWAAGCGD 218


>UniRef50_UPI000187D203 hypothetical protein MPER_09068 n=1 Tax=Moniliophthora perniciosa
          FA553 RepID=UPI000187D203
          Length = 73

 Score = 46.6 bits (109), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 30/69 (43%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 4  VQFSHNPL-FCIDIIKTYKPDF--TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
          VQ S +P    ID I    P     PRV  I GSGL  LA  ++  V + Y+ LPGF  S
Sbjct: 3  VQGSASPFDATIDTIHRIVPQNLQKPRVGIICGSGLSGLAASLKETVPLPYDTLPGFAQS 62

Query: 61 TVHGHAGEL 69
          TV GH   L
Sbjct: 63 TVPGHKSSL 71


>UniRef50_A7I6C4 Purine phosphorylase, family 2 n=2 Tax=Genera incertae sedis
           RepID=A7I6C4_METB6
          Length = 223

 Score = 46.6 bits (109), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 42/169 (24%), Positives = 77/169 (45%), Gaps = 11/169 (6%)

Query: 108 GCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAE 167
           G + +    ++GSL+ E+  G+ +   D++ +M   P   ++D        ++ +     
Sbjct: 65  GVDHIVAFGSSGSLKKEIPPGTTLIPTDYV-SMADIP--SIHD-------HAIEHVRPEL 114

Query: 168 YRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHC 227
            RAL +K+A         GV+V   GP  ET  E+  +  I  DVVGM+V  E   A   
Sbjct: 115 SRALAEKLAAVVPEARLGGVYVQTRGPRIETVTEVAALAQIA-DVVGMTVASEATLACEL 173

Query: 228 DLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           D++  A+  I N A GL    L+    L+ ++   +    ++   +R++
Sbjct: 174 DMEFAALCTIDNYANGLGAEVLTFEHILSISKAHSRRTEEVLGAIIREM 222


>UniRef50_D0NYY4 Putative uncharacterized protein n=1 Tax=Phytophthora infestans
           T30-4 RepID=D0NYY4_PHYIN
          Length = 265

 Score = 46.2 bits (108), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 47/196 (23%), Positives = 78/196 (39%), Gaps = 29/196 (14%)

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
           G + + R +     A+   K L CE +    + GS+ P+VG G  V  +D  +       
Sbjct: 71  GKYRQPRKINFRAIAL-ALKSLRCEAVVGIYSVGSMTPKVGVGRFVVPEDFFSPF----- 124

Query: 146 VGLNDDRFGERFFSLANAYDAEY---------RALLQKVAKEEGFPLTEGVFVSYPGPNF 196
                         ++  YDA            AL+Q +      P   GV+V   GP F
Sbjct: 125 ----------DIMHVSKDYDAHVVPELHAKLKTALVQALTGGGFDPHDGGVYVQTAGPRF 174

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD---VKLSHAQ 253
           ET +E+R      G ++GM+   E        +     S + NMA G+ D   ++   A 
Sbjct: 175 ETKSEVRFFAQF-GQLIGMTGANEAELLNELRVPFAMFSIVDNMANGMGDPLTLEAFKAT 233

Query: 254 TLAAAELSKQNFINLI 269
             A A+L ++ F++ +
Sbjct: 234 QKANADLMERAFVHTL 249


>UniRef50_C3Y9W3 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3Y9W3_BRAFL
          Length = 239

 Score = 46.2 bits (108), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 20/130 (15%)

Query: 122 RPEVGAGSLVALKDHINTM-----------PGTPMVGLNDDRFGERFFSLANAYDAEYRA 170
           R ++  G +V L   I+             PG+P+        G     +   +    R 
Sbjct: 52  REDIHPGDMVILDQFIDRTTKRATTFYDGNPGSPL--------GVCHLPMDTPFCPHTRK 103

Query: 171 LLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDL 229
           +L  V KE      E G  V+  GP F + AE +M ++ GGDV+ M+ VPEV  A+   +
Sbjct: 104 ILIDVCKELEIRHHESGTMVTIEGPRFSSRAESKMFRMWGGDVINMTTVPEVALAKEAGM 163

Query: 230 KVVAVSAITN 239
              AV+  T+
Sbjct: 164 CYAAVAMATD 173


>UniRef50_UPI000038E4F5 5''''-methylthioadenosine phosphorylase II n=1 Tax=Ferroplasma
           acidarmanus fer1 RepID=UPI000038E4F5
          Length = 257

 Score = 45.8 bits (107), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 41/166 (24%), Positives = 73/166 (43%), Gaps = 6/166 (3%)

Query: 59  VSTVHGH-AGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDA-IRTFKLLGCELLFCTN 116
           + T +G  +  L +G + GV V  +   G  +      +   A I   +  G + +   N
Sbjct: 24  IDTPYGKPSAPLEIGEINGVEVAFLPRHGKKHTIPPHMVNYKANIFALQKAGVQRIIGLN 83

Query: 117 AAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVA 176
           A GSL+ E   G +V     I+      +   N         S+A+ + ++  A   +  
Sbjct: 84  AVGSLKEEYKPGDIVIPDQFIDFTKRRDLTYYNGPDV--YHISMADPFCSDISAKAYEAG 141

Query: 177 KEEGFPL-TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEV 221
           K+  FP+   G ++   GP F T AE +M +    D++GM++VPE+
Sbjct: 142 KKLSFPVHKNGAYICIEGPRFSTRAESKMFRNF-ADIIGMTLVPEI 186


>UniRef50_C1C2B0 S-methyl-5-thioadenosine phosphorylase n=2 Tax=Caligus
           RepID=C1C2B0_9MAXI
          Length = 283

 Score = 45.8 bits (107), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 41/176 (23%), Positives = 73/176 (41%), Gaps = 5/176 (2%)

Query: 69  LVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGA 127
           LV G + G+ V+ +    H        +   A I   +  G   +    A  SL+ +   
Sbjct: 48  LVSGKIDGIDVIFLSRHSHDKRFNPSEVNYKANIDALRQAGVTHILAATACESLQDDKKP 107

Query: 128 GSLVALKDHIN--TMPGTPMVGL-NDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL- 183
              V L   I+  T        L N D     F  +  ++    R ++ +V  + G  + 
Sbjct: 108 EEFVILDSFIDRTTKRKQTFYDLSNPDDHSCAFIPMHPSFCERSRKIVYEVGSKMGLKVH 167

Query: 184 TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
            +G  V+  GP F + AE  + +    DV+ M+ VPEV+ A+   +  V+V+ +T+
Sbjct: 168 PKGTIVTIEGPRFSSKAESLVFKSWNADVINMTTVPEVVLAKEAGISYVSVAMVTD 223


>UniRef50_UPI00016A8371 5''''-methylthioadenosine phosphorylase n=2 Tax=pseudomallei group
           RepID=UPI00016A8371
          Length = 271

 Score = 45.4 bits (106), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 36/122 (29%), Positives = 58/122 (47%), Gaps = 6/122 (4%)

Query: 159 SLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAEI----RMMQIIGGDVV 213
           S+   +DA  RA     A + G  L T+G+++   G  FE+AAE+    R+ Q     V+
Sbjct: 145 SMREPFDARLRANFALAAGKVGAKLLTQGLYIQSGGDAFESAAEVETYRRVYQGRRNRVL 204

Query: 214 GMSVVPEVISARHCDLKVVAVSAITNMAEGLS-DVKLSHAQTLAAAELSKQNFINLICGF 272
           GM+   E++  R  ++    + A  N AEGL  D  ++HA  LA  + +      +    
Sbjct: 205 GMTAGAELVLCRQMEIPYALICANCNWAEGLDPDNAVTHAFVLAGMQPAAATLAKIAEAV 264

Query: 273 LR 274
           LR
Sbjct: 265 LR 266


>UniRef50_Q7TP15 Cc1-6 n=9 Tax=Coelomata RepID=Q7TP15_RAT
          Length = 391

 Score = 44.3 bits (103), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 45/81 (55%), Gaps = 1/81 (1%)

Query: 160 LANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVV 218
           +A  +  + R +L ++AK+ G    ++G  V+  GP F + AE  + +  G DV+ M+ V
Sbjct: 223 MAEPFCPKTREVLIEMAKKLGLRCHSKGTIVTIEGPRFSSRAESFIFRTWGADVINMTTV 282

Query: 219 PEVISARHCDLKVVAVSAITN 239
           PEV+ A+   L   +++  T+
Sbjct: 283 PEVVLAKEAGLCYASIAMATD 303


>UniRef50_C5KDS7 Methylthioadenosine/purine nucleoside phosphorylase, putative n=2
           Tax=Perkinsus marinus ATCC 50983 RepID=C5KDS7_9ALVE
          Length = 204

 Score = 44.3 bits (103), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 42/162 (25%), Positives = 66/162 (40%), Gaps = 30/162 (18%)

Query: 109 CELLFCTNAAGSLRPEV-GAGSLVALKDHINTMP--------GTPMVGLNDDRFGERFFS 159
           C+ +    + GS+RP++   G +    D I+  P        G P VG      G   ++
Sbjct: 10  CDKIIALASVGSIRPDLFKIGDIAVPTDFIDFAPQRGTMTFWGNPDVGPFSGEKGRIHYT 69

Query: 160 LANAYDAEYRALLQKVAKEEGFPLTEG----------------VFVSYPGPNFETAAEIR 203
             +  D  +R   +K+A    FP  EG                V+    GP FE+ AE+R
Sbjct: 70  PCDHDDHVWR---KKIAGTL-FPFQEGPHIVSLSEANETETDVVYTQTNGPRFESRAEVR 125

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           M+Q   G +VGM+   E   A    +    V+ + N+  GL 
Sbjct: 126 MLQRY-GHLVGMTCASEWTLAGELGVPYAIVAMVDNLGNGLD 166


>UniRef50_A4X3Q9 Methylthioadenosine phosphorylase n=8 Tax=Actinomycetales
           RepID=A4X3Q9_SALTO
          Length = 267

 Score = 43.9 bits (102), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 55/244 (22%), Positives = 90/244 (36%), Gaps = 28/244 (11%)

Query: 22  PDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV-LGHLQGVPVV 80
           P+    +  I G+GL  L  + E              +ST +G   +L+ +  L    V 
Sbjct: 4   PNLNADIGVIGGTGLYELLGETEE-----------VKISTPYGAPSDLITVAELNSRQVA 52

Query: 81  CMK--GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
            +   GR H +    +    + I   + LG   +    A G LRP+  AG+ V     I+
Sbjct: 53  FLPRHGRDHRFPPHRIPYRAN-IWALRSLGVRQILAPCAVGGLRPDFIAGTFVVPDQLID 111

Query: 139 TMPGTPMV----GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGP 194
              G        G     F E +              + +V          G  V   GP
Sbjct: 112 RTSGREQTFCDTGAVHTTFAEPYCPDGRRAALAAAERVNRVDG--------GTMVVIDGP 163

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQ 253
            F T AE R     GG ++ M+  PE   AR   L   +++ +T++  G+   + ++H +
Sbjct: 164 RFSTRAESRWHAAAGGTIINMTGQPEAALARELALCYTSIALVTDLDAGVEGSQGVTHDE 223

Query: 254 TLAA 257
            L A
Sbjct: 224 VLRA 227


>UniRef50_C0W509 Possible purine-nucleoside phosphorylase n=1 Tax=Actinomyces
           urogenitalis DSM 15434 RepID=C0W509_9ACTO
          Length = 283

 Score = 43.9 bits (102), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 45/171 (26%), Positives = 69/171 (40%), Gaps = 16/171 (9%)

Query: 54  LPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLF 113
           LPG     V G    L      G+ V+  +GR   YEG+    +T   R     G     
Sbjct: 65  LPGVSAPQVPGQEDLLTSHDRGGLGVLVARGRTCLYEGKPARRVTGLARLAAGAGVRAAL 124

Query: 114 CTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEY-RALL 172
             + A SL  +   G  +A+ DH+N + G+P+            F      DA +   L 
Sbjct: 125 MVSRASSLG-QASLGDFLAVADHLN-LTGSPL------------FPATQCVDASWDEDLT 170

Query: 173 QKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVIS 223
             V++ +G     GV    PGP   + +E+ +M  +G D V M  V E ++
Sbjct: 171 NAVSRIDGV-RGAGVAALVPGPVRPSRSEVTLMSGLGADAVVMDGVAEAMA 220


>UniRef50_A8RJ25 Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC
           BAA-613 RepID=A8RJ25_9CLOT
          Length = 289

 Score = 43.5 bits (101), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 40/164 (24%), Positives = 72/164 (43%), Gaps = 10/164 (6%)

Query: 88  FYEGRGMTIMTD--AIRTFKLL---GCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
           F+  +G++   D  + R F  L   G + +    + G + P +  G ++  +D I+    
Sbjct: 75  FHGWKGLSPYNDTPSERIFWALREAGVKYILADGSGGGINPLLEPGDIICPQDFIDYTKR 134

Query: 143 TPMVGLNDDRFGERFFSLANAYDAE-YRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAE 201
              +G    +F      +      + +R LL+K +         G++     P FE+AAE
Sbjct: 135 VSYLG----KFTPYSMRMREIICPDLHRILLEKASGVFRRVFRTGIYGVAEAPRFESAAE 190

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           I+ M     DV G +++PE   AR       A+  I+N AEG++
Sbjct: 191 IQKMYADHCDVCGQTMMPEAALARAIGACYAALYVISNSAEGIN 234


>UniRef50_Q2RHE2 Purine phosphorylase, family 2 n=1 Tax=Moorella thermoacetica ATCC
           39073 RepID=Q2RHE2_MOOTA
          Length = 283

 Score = 43.5 bits (101), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 39/75 (52%), Gaps = 2/75 (2%)

Query: 172 LQKVAKEE--GFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDL 229
           L + A+E   G     GV++   G +FE+AAE+ + +  G DVVG ++ PEV  AR    
Sbjct: 151 LVETARESPLGRVFDRGVYLVTDGRHFESAAEVSLFRQWGADVVGQTLCPEVYLAREMGA 210

Query: 230 KVVAVSAITNMAEGL 244
               +  + N  EG+
Sbjct: 211 CYAGIYLVVNYGEGV 225


>UniRef50_Q09816 Uncharacterized protein C16C9.02c n=49 Tax=cellular organisms
           RepID=YAC2_SCHPO
          Length = 307

 Score = 42.4 bits (98), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 53/221 (23%), Positives = 85/221 (38%), Gaps = 23/221 (10%)

Query: 31  ILGSGLGALA--DQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHF 88
           I GSG   L   D +E+   I+    P  P+S     +G L+         +   G GH 
Sbjct: 13  IGGSGFYDLPGFDIVESVNPITPWGYPASPISIARTTSGFLIA-------FLARHGVGHI 65

Query: 89  YEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN-TMPGTPMVG 147
           Y    +    + I   K LG   +   +A GSLR ++     V     I+ T+   P   
Sbjct: 66  YTPTEVPSRAN-IAALKSLGVLAIVSFSAVGSLREDIPPEDFVLPTQIIDRTLCARPNTF 124

Query: 148 LND---------DRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFET 198
                       D F +  + + ++  +  +   +   K +G  LT    V   GP F T
Sbjct: 125 FESGCVAHVSFGDPFDQDLYEILSSCGSNLKNGSKLHTKRKGDDLT---VVCMEGPAFST 181

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
            AE  + +  G  ++ MSV+PE   AR  ++    V   T+
Sbjct: 182 RAESNLYRSWGASIINMSVIPEAKLAREAEIAYQMVCMATD 222


>UniRef50_UPI0001C31DF7 S-methyl-5''''-thioadenosine phosphorylase n=1 Tax=Conexibacter
           woesei DSM 14684 RepID=UPI0001C31DF7
          Length = 264

 Score = 42.4 bits (98), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 37/146 (25%), Positives = 60/146 (41%), Gaps = 10/146 (6%)

Query: 108 GCELLFCTNAAGSLRPEVGAGSLVALKD---HINTMPGTPMVGLNDDR----FGERFFSL 160
           G + +      GSL   +  G+LV   D     N +P   +  L+DD      G   F L
Sbjct: 74  GVDAIVAVTICGSLDASLPPGALVVFDDLYFPSNRLPDGSICTLHDDPGASGRGHWIFDL 133

Query: 161 ANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVP 219
              +    R  L   A+  G+   +G  +    GP F T AE+R +  IG   V  +  P
Sbjct: 134 P--FSQPLREALLTGARSAGYAARDGGCYAHTDGPRFNTRAELRALMQIGVKAVSQTAGP 191

Query: 220 EVISARHCDLKVVAVSAITNMAEGLS 245
           E++ +    +    +  IT+ A G++
Sbjct: 192 EIVLSGEAGVPYALLGFITDYANGIN 217


>UniRef50_C5TP90 Methylthioadenosine phosphorylase n=5 Tax=Neisseria
           RepID=C5TP90_NEIFL
          Length = 238

 Score = 42.0 bits (97), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 35/141 (24%), Positives = 56/141 (39%), Gaps = 1/141 (0%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSL 160
           I     LG E +   ++   + P+   GSLV   D I+   G                  
Sbjct: 68  IWALHSLGVENIIAISSVVGINPDFENGSLVLPDDLIDYTYGRKDTFFEGQECPVVHTDF 127

Query: 161 ANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVP 219
            N Y  E R  L  + K    P+ +  V+    GP   T AEI   +  G DV+GM+ +P
Sbjct: 128 FNPYCDELRQELLNITKAHNVPIYDSAVYGCLQGPRRPTRAEIARYRRDGVDVLGMTGMP 187

Query: 220 EVISARHCDLKVVAVSAITNM 240
           E + AR   +      +++++
Sbjct: 188 EAVLARELKMAYAHFCSVSSI 208


>UniRef50_A4IXW9 Phosphorylase family 2/alpha-beta hydrolase fold protein n=18
           Tax=Francisella RepID=A4IXW9_FRATW
          Length = 611

 Score = 40.4 bits (93), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 43/180 (23%), Positives = 70/180 (38%), Gaps = 17/180 (9%)

Query: 101 IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGER---- 156
           I   K  G   +   ++  SLR E+  G +V     I+         L +  F E+    
Sbjct: 68  IYALKKYGATSIIALSSVRSLREELKPGDMVIPYQFIDRTKS-----LREFTFCEQGLLN 122

Query: 157 FFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIRMMQIIGGDVVGM 215
           + SL+          ++   KE  F +  +  +V   GP F T  + +  Q +GG V+GM
Sbjct: 123 YVSLSKPITESIAEEIRAKKKEFDFEIHFKQSYVCIEGPQFPTIIDAKCFQSMGGGVIGM 182

Query: 216 SVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-------LSHAQTLAAAELSKQNFINL 268
           +  PE   AR   L  ++ + I +      DV+       +     L A +L K    NL
Sbjct: 183 TAFPEFALAREAGLNYISCNFIVDYVPWSYDVRNLYNVLEIRETSNLKAEKLVKWLVNNL 242


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_P45563 Xanthosine phosphorylase n=57 Tax=cellular organ...   385   e-106
UniRef50_B5R3U9 Xanthosine phosphorylase n=53 Tax=Enterobacteria...   373   e-102
UniRef50_P77834 Purine nucleoside phosphorylase 1 n=41 Tax=Bacil...   368   e-100
UniRef50_Q2B6A0 Purine nucleoside phosphorylase n=12 Tax=Bacilli...   363   5e-99
UniRef50_P46354 Purine nucleoside phosphorylase 1 n=69 Tax=Bacte...   360   2e-98
UniRef50_Q65HU0 PunA n=9 Tax=Firmicutes RepID=Q65HU0_BACLD            359   4e-98
UniRef50_A7GSB0 Purine nucleoside phosphorylase I, inosine and g...   359   8e-98
UniRef50_B1YM96 Purine nucleoside phosphorylase I, inosine and g...   354   1e-96
UniRef50_A3DEQ4 Purine nucleoside phosphorylase I, inosine and g...   344   2e-93
UniRef50_A6BDL0 Putative uncharacterized protein n=1 Tax=Dorea l...   344   2e-93
UniRef50_A9KIZ4 Inosine guanosine and xanthosine phosphorylase f...   339   6e-92
UniRef50_C1F7J2 Purine nucleoside phosphorylase I, inosine and g...   339   8e-92
UniRef50_B9MKK7 Inosine guanosine and xanthosine phosphorylase f...   337   3e-91
UniRef50_A5IBS6 Xanthosine phosphorylase n=5 Tax=Legionella RepI...   334   2e-90
UniRef50_A6NWZ5 Putative uncharacterized protein n=1 Tax=Bactero...   333   4e-90
UniRef50_B8HVY6 Inosine guanosine and xanthosine phosphorylase f...   331   1e-89
UniRef50_Q23U21 Purine nucleoside phosphorylase n=1 Tax=Tetrahym...   330   3e-89
UniRef50_A9KIE8 Inosine guanosine and xanthosine phosphorylase f...   329   8e-89
UniRef50_P00491 Purine nucleoside phosphorylase n=19 Tax=Coeloma...   328   1e-88
UniRef50_Q1IM44 Purine nucleoside phosphorylase I, inosine and g...   328   1e-88
UniRef50_B6J4B4 Xanthosine phosphorylase n=8 Tax=Gammaproteobact...   327   3e-88
UniRef50_A6GZM2 Purine-nucleoside phosphorylase n=3 Tax=Bacteroi...   326   4e-88
UniRef50_P23492 Purine nucleoside phosphorylase n=47 Tax=Metazoa...   325   1e-87
UniRef50_Q6MGR6 Pnp protein n=1 Tax=Bdellovibrio bacteriovorus R...   323   3e-87
UniRef50_C7M8V2 Inosine guanosine and xanthosine phosphorylase f...   323   3e-87
UniRef50_C9LGF9 Purine nucleoside phosphorylase I, inosine and g...   322   6e-87
UniRef50_A7S700 Predicted protein n=3 Tax=cellular organisms Rep...   322   6e-87
UniRef50_C1TMH4 Purine nucleoside phosphorylase I, inosine and g...   322   1e-86
UniRef50_D0LL71 Purine nucleoside phosphorylase I, inosine and g...   321   2e-86
UniRef50_D0NTD2 Purine nucleoside phosphorylase 1 n=5 Tax=cellul...   321   2e-86
UniRef50_Q95TC1 GH03781p n=13 Tax=cellular organisms RepID=Q95TC...   319   5e-86
UniRef50_UPI0000522022 PREDICTED: similar to nucleoside phosphor...   318   1e-85
UniRef50_D1B5G3 Inosine guanosine and xanthosine phosphorylase f...   314   2e-84
UniRef50_Q7KV94 CG16758, isoform B n=33 Tax=cellular organisms R...   314   2e-84
UniRef50_Q3B5L6 Purine nucleoside phosphorylase I, inosine and g...   313   4e-84
UniRef50_C3J8Q8 Purine nucleoside phosphorylase I, inosine and g...   313   5e-84
UniRef50_C4QLI3 Purine nucleoside phosphorylase n=2 Tax=Schistos...   313   5e-84
UniRef50_B6YR86 Purine-nucleoside phosphorylase n=1 Tax=Candidat...   312   7e-84
UniRef50_C8V0B3 Purine nucleoside phosphorylase I, inosine and g...   312   8e-84
UniRef50_Q0TU47 Purine nucleoside phosphorylase n=7 Tax=Clostrid...   312   1e-83
UniRef50_B0VG85 Purine nucleoside phosphorylase 1 (Purine nucleo...   311   2e-83
UniRef50_D0MFN5 Inosine guanosine and xanthosine phosphorylase f...   311   2e-83
UniRef50_C3ZRV1 Putative uncharacterized protein (Fragment) n=1 ...   311   2e-83
UniRef50_A7HJP7 Purine nucleoside phosphorylase I, inosine and g...   310   3e-83
UniRef50_D1Y3S3 Purine nucleoside phosphorylase I, inosine and g...   310   3e-83
UniRef50_A0NS72 Purine nucleoside phosphorylase n=7 Tax=Alphapro...   310   4e-83
UniRef50_Q9BMI9 Purine-nucleoside phosphorylase n=1 Tax=Schistos...   310   4e-83
UniRef50_B9WDS7 Purine nucleoside phosphorylase, putative n=14 T...   309   5e-83
UniRef50_A7VBG8 Putative uncharacterized protein n=2 Tax=Clostri...   309   9e-83
UniRef50_D2MQ16 Purine nucleoside phosphorylase I, inosine and g...   308   1e-82
UniRef50_A8PXS8 Purine nucleoside phosphorylase I, inosine and g...   308   1e-82
UniRef50_Q5YBA4 Purine nucleoside phosphorylase n=2 Tax=Singapor...   306   4e-82
UniRef50_C7LVA5 Inosine guanosine and xanthosine phosphorylase f...   305   1e-81
UniRef50_A5USV0 Inosine guanosine and xanthosine phosphorylase f...   305   1e-81
UniRef50_A4CJ72 Purine nucleoside phosphorylase n=15 Tax=Bactero...   304   2e-81
UniRef50_D2QX64 Purine nucleoside phosphorylase I, inosine and g...   303   5e-81
UniRef50_B9XJR6 Inosine guanosine and xanthosine phosphorylase f...   302   9e-81
UniRef50_C7MNU9 Inosine guanosine and xanthosine phosphorylase f...   302   1e-80
UniRef50_C5EQ75 Purine nucleoside phosphorylase I n=1 Tax=Clostr...   302   1e-80
UniRef50_B7A7P1 Inosine guanosine and xanthosine phosphorylase f...   299   7e-80
UniRef50_C1AAZ0 Purine nucleoside phosphorylase n=1 Tax=Gemmatim...   297   2e-79
UniRef50_A3ZZ29 Purine nucleoside phosphorylase n=1 Tax=Blastopi...   296   9e-79
UniRef50_B2KC58 Inosine guanosine and xanthosine phosphorylase f...   295   1e-78
UniRef50_Q311R2 Inosine guanosine and xanthosine phosphorylase n...   295   1e-78
UniRef50_Q1NL01 Inosine guanosine and xanthosine phosphorylase:P...   293   3e-78
UniRef50_C3FBK6 Purine nucleoside phosphorylase I, inosine and g...   293   4e-78
UniRef50_C1C0Q7 Purine nucleoside phosphorylase n=2 Tax=Caligus ...   293   4e-78
UniRef50_A9BH77 Purine nucleoside phosphorylase I, inosine and g...   293   5e-78
UniRef50_Q05788 Purine nucleoside phosphorylase n=10 Tax=Sacchar...   292   1e-77
UniRef50_B4D4P3 Inosine guanosine and xanthosine phosphorylase f...   291   2e-77
UniRef50_C0BWU4 Putative uncharacterized protein n=1 Tax=Clostri...   290   3e-77
UniRef50_Q11C51 Inosine guanosine and xanthosine phosphorylase f...   289   5e-77
UniRef50_Q472Z5 Purine nucleotide phosphorylase:Inosine guanosin...   289   1e-76
UniRef50_A9URE9 Predicted protein n=1 Tax=Monosiga brevicollis R...   288   1e-76
UniRef50_A9G8Q6 DeoD protein n=8 Tax=Bacteria RepID=A9G8Q6_SORC5      287   2e-76
UniRef50_B6K0G6 Purine nucleoside phosphorylase n=1 Tax=Schizosa...   285   1e-75
UniRef50_B1GZW7 Purine nucleoside phosphorylase n=1 Tax=uncultur...   285   1e-75
UniRef50_C5NWB5 Purine nucleoside phosphorylase 1 n=1 Tax=Gemell...   282   8e-75
UniRef50_Q9UTG1 Putative purine nucleoside phosphorylase n=4 Tax...   281   2e-74
UniRef50_B8J4B5 Inosine guanosine and xanthosine phosphorylase f...   279   6e-74
UniRef50_B3QTH8 Inosine guanosine and xanthosine phosphorylase f...   278   1e-73
UniRef50_C7NVB1 Inosine guanosine and xanthosine phosphorylase f...   278   1e-73
UniRef50_Q2S0P3 Purine nucleoside phosphorylase n=1 Tax=Saliniba...   274   3e-72
UniRef50_B7GAT6 Predicted protein (Fragment) n=2 Tax=Bacillariop...   273   5e-72
UniRef50_Q11M20 Inosine guanosine and xanthosine phosphorylase f...   270   3e-71
UniRef50_C5P2F4 Purine nucleoside phosphorylase, putative n=2 Ta...   266   6e-70
UniRef50_B4MDV7 GJ18292 n=4 Tax=Drosophila RepID=B4MDV7_DROVI         265   8e-70
UniRef50_B8ICG2 Purine nucleotide phosphorylase n=28 Tax=Alphapr...   265   1e-69
UniRef50_Q3A2Z8 Xanthosine phosphorylase n=1 Tax=Pelobacter carb...   262   1e-68
UniRef50_D2QX63 Inosine guanosine and xanthosine phosphorylase f...   261   2e-68
UniRef50_D2L8K6 Inosine guanosine and xanthosine phosphorylase f...   259   6e-68
UniRef50_B0D4C6 Predicted protein n=3 Tax=Agaricales RepID=B0D4C...   259   1e-67
UniRef50_B9ZYX1 Nucleoside phosphorylase n=1 Tax=Dicyema japonic...   254   3e-66
UniRef50_O57865 Uncharacterized protein PH0125 n=36 Tax=Archaea ...   253   5e-66
UniRef50_P46862 Purine nucleoside phosphorylase n=79 Tax=Actinom...   252   1e-65
UniRef50_Q2CJ93 Purine nucleoside phosphorylase n=1 Tax=Oceanico...   249   7e-65
UniRef50_P81989 Purine nucleoside phosphorylase n=7 Tax=Actinoba...   246   6e-64
UniRef50_A2FHY6 Inosine guanosine and xanthosine phosphorylase f...   245   1e-63
UniRef50_D1BYW2 Purine nucleotide phosphorylase n=6 Tax=Actinomy...   245   2e-63
UniRef50_Q1K0Y4 Inosine guanosine and xanthosine phosphorylase n...   240   6e-62
UniRef50_C4FCF5 Putative uncharacterized protein n=2 Tax=Collins...   238   1e-61
UniRef50_Q28ZG3 GA14805 n=2 Tax=pseudoobscura subgroup RepID=Q28...   238   2e-61
UniRef50_Q83H43 Purine nucleoside phosphorylase n=3 Tax=Trophery...   237   4e-61
UniRef50_Q7URV0 Purine nucleoside phosphorylase I n=1 Tax=Rhodop...   236   8e-61
UniRef50_C7MEB8 Purine nucleotide phosphorylase n=2 Tax=Micrococ...   235   9e-61
UniRef50_Q0W2D2 Putative purine phosphorylase (Family 2) n=1 Tax...   235   2e-60
UniRef50_C5C9E7 Purine nucleotide phosphorylase n=3 Tax=Actinomy...   234   3e-60
UniRef50_B9CNR2 Purine nucleoside phosphorylase 1 n=2 Tax=Atopob...   232   2e-59
UniRef50_D2VAE0 Purine phosphorylase family protein n=1 Tax=Naeg...   230   4e-59
UniRef50_Q13126 S-methyl-5'-thioadenosine phosphorylase n=55 Tax...   224   2e-57
UniRef50_A8B9X8 Purine nucleoside phosphorylase lateral transfer...   224   2e-57
UniRef50_C0QPX3 Methylthioadenosine phosphorylase n=6 Tax=Aquifi...   224   3e-57
UniRef50_O27633 Methylthioadenosine phosphorylase n=7 Tax=Archae...   223   4e-57
UniRef50_B3T2V4 Putative phosphorylase family 2 n=2 Tax=environm...   222   8e-57
UniRef50_B0K2V3 Purine phosphorylase, family 2 n=10 Tax=Thermoan...   222   8e-57
UniRef50_B1I2E1 Methylthioadenosine phosphorylase n=33 Tax=cellu...   221   2e-56
UniRef50_A3DD28 Methylthioadenosine phosphorylase n=7 Tax=Clostr...   221   2e-56
UniRef50_Q9W1K6 CG18128 n=7 Tax=melanogaster group RepID=Q9W1K6_...   221   3e-56
UniRef50_A9A3N5 Methylthioadenosine phosphorylase n=4 Tax=Archae...   220   3e-56
UniRef50_B9KXK8 Purine nucleoside phosphorylase n=2 Tax=Thermomi...   220   5e-56
UniRef50_Q7ZV22 Methylthioadenosine phosphorylase n=20 Tax=Metaz...   218   2e-55
UniRef50_B5Y8G4 Methylthioadenosine phosphorylase n=1 Tax=Coprot...   215   2e-54
UniRef50_UPI000038E4F5 5''''-methylthioadenosine phosphorylase I...   214   2e-54
UniRef50_B3RV47 Putative uncharacterized protein n=1 Tax=Trichop...   213   6e-54
UniRef50_Q60367 Uncharacterized protein MJ0060 n=11 Tax=Methanoc...   213   7e-54
UniRef50_D0JB48 Purine nucleoside phosphorylase n=2 Tax=Blattaba...   212   1e-53
UniRef50_D2RKT9 Purine or other phosphorylase family 1 n=1 Tax=A...   212   1e-53
UniRef50_A4U101 Purine phosphorylase, family 2 n=4 Tax=Proteobac...   210   4e-53
UniRef50_Q0BRD3 5'-methylthioadenosine phosphorylase n=113 Tax=c...   210   6e-53
UniRef50_A3EWJ6 Methylthioadenosine phosphorylase n=2 Tax=Leptos...   208   2e-52
UniRef50_Q18KQ3 5'-methylthioadenosine phosphorylase MtaP n=4 Ta...   208   2e-52
UniRef50_Q3ZZT2 Methylthioadenosine phosphorylase n=7 Tax=cellul...   207   3e-52
UniRef50_B9KZC3 Methylthioadenosine phosphorylase n=2 Tax=Bacter...   207   3e-52
UniRef50_Q465I0 Methylthioadenosine phosphorylase n=4 Tax=Methan...   207   4e-52
UniRef50_C0W9U9 Purine nucleoside phosphorylase n=1 Tax=Acidamin...   207   4e-52
UniRef50_A9BDU8 5'-methylthioadenosine phosphorylase n=13 Tax=Cy...   207   4e-52
UniRef50_C5EEL8 Purine nucleoside phosphorylase n=1 Tax=Clostrid...   206   9e-52
UniRef50_Q1NY44 Methylthioadenosine phosphorylase n=2 Tax=delta ...   206   9e-52
UniRef50_B4U6Q8 Purine phosphorylase family 2 n=2 Tax=Aquificace...   204   3e-51
UniRef50_D1YZM1 5'-methylthioadenosine phosphorylase n=1 Tax=Met...   203   5e-51
UniRef50_C6HVW5 Methylthioadenosine phosphorylase n=1 Tax=Leptos...   203   6e-51
UniRef50_Q16MW6 Methylthioadenosine phosphorylase n=6 Tax=Neopte...   203   6e-51
UniRef50_D1A6L7 Methylthioadenosine phosphorylase n=16 Tax=Actin...   203   6e-51
UniRef50_Q5Z1K2 Putative methylthioadenosine phosphorylase n=4 T...   203   7e-51
UniRef50_B1GZW8 S-methyl-5'-thioadenosine phosphorylase n=1 Tax=...   202   8e-51
UniRef50_Q2S4Q1 Purine nucleoside phosphorylase I, inosine and g...   202   9e-51
UniRef50_Q87ZC3 Probable S-methyl-5'-thioadenosine phosphorylase...   201   3e-50
UniRef50_Q21JS6 Methylthioadenosine phosphorylase n=1 Tax=Saccha...   201   3e-50
UniRef50_D1C2Y0 Methylthioadenosine phosphorylase n=2 Tax=Bacter...   200   6e-50
UniRef50_Q0F2U5 Purine nucleoside phosphorylase n=1 Tax=Mariprof...   199   1e-49
UniRef50_P74469 Sll0135 protein n=67 Tax=cellular organisms RepI...   197   3e-49
UniRef50_Q47F96 Methylthioadenosine phosphorylase n=7 Tax=Betapr...   197   5e-49
UniRef50_C7LA98 FI12502p (Fragment) n=14 Tax=Drosophila RepID=C7...   197   5e-49
UniRef50_C3ZRU9 Putative uncharacterized protein n=1 Tax=Branchi...   196   8e-49
UniRef50_B4CZS2 Methylthioadenosine phosphorylase n=1 Tax=Chthon...   196   9e-49
UniRef50_A9GWF6 5'-methyl-5-thioadenosine phosphorylase n=1 Tax=...   196   9e-49
UniRef50_A3TNF6 Methylthioadenosine phosphorylase n=1 Tax=Janiba...   194   2e-48
UniRef50_C4Q4X0 Methylthioadenosine phosphorylase, putative n=1 ...   194   3e-48
UniRef50_C8R2U4 Methylthioadenosine phosphorylase n=1 Tax=Desulf...   193   7e-48
UniRef50_C2KQL7 Possible purine-nucleoside phosphorylase n=2 Tax...   192   9e-48
UniRef50_UPI00016C3D31 inosine guanosine and xanthosine phosphor...   191   2e-47
UniRef50_A6GFX4 Purine nucleoside phosphorylase n=1 Tax=Plesiocy...   191   3e-47
UniRef50_Q87BR7 Probable S-methyl-5'-thioadenosine phosphorylase...   190   7e-47
UniRef50_B0DVC8 Predicted protein n=3 Tax=Basidiomycota RepID=B0...   189   8e-47
UniRef50_Q1PVD3 Similar to 5'-methylthioadenosine phosphorylase ...   188   1e-46
UniRef50_C6DE56 Methylthioadenosine phosphorylase n=1 Tax=Pectob...   188   1e-46
UniRef50_Q1H1A2 Methylthioadenosine phosphorylase n=3 Tax=Bacter...   188   1e-46
UniRef50_B7RUB3 Phosphorylases family 2 n=1 Tax=marine gamma pro...   187   3e-46
UniRef50_D2V2R7 5'-methylthioadenosine phosphorylase n=1 Tax=Nae...   186   6e-46
UniRef50_B5EMB0 Methylthioadenosine phosphorylase n=15 Tax=Prote...   185   1e-45
UniRef50_B5YKP5 S-methyl-5-thioadenosine phosphorylase n=1 Tax=T...   185   2e-45
UniRef50_C1SHM5 Purine nucleoside phosphorylase n=1 Tax=Denitrov...   183   4e-45
UniRef50_A4AL37 5'-methylthioadenosine phosphorylase n=3 Tax=Act...   183   7e-45
UniRef50_O28486 Methylthioadenosine phosphorylase (MtaP) n=1 Tax...   181   1e-44
UniRef50_B8KGW0 Purine phosphorylase, family 2 n=1 Tax=gamma pro...   181   3e-44
UniRef50_A2VPA1 Purine nucleoside phosphorylase deoD n=1 Tax=Myc...   180   3e-44
UniRef50_A0YHC5 Methylthioadenosine phosphorylase n=1 Tax=marine...   179   8e-44
UniRef50_A7BPC6 Purine phosphorylase, family 2 n=2 Tax=Gammaprot...   179   1e-43
UniRef50_C1C2B0 S-methyl-5-thioadenosine phosphorylase n=2 Tax=C...   179   1e-43
UniRef50_C1YKP8 Inosine guanosine and xanthosine phosphorylase f...   178   2e-43
UniRef50_Q5C0P1 SJCHGC05230 protein (Fragment) n=1 Tax=Schistoso...   176   6e-43
UniRef50_Q9RIJ1 Purine nucleoside phosphorylase homolog (Fragmen...   176   9e-43
UniRef50_B5ICA6 Phosphorylases family 2 n=2 Tax=Aciduliprofundum...   175   2e-42
UniRef50_Q5KPU2 Glutamate biosynthesis-related protein, putative...   171   3e-41
UniRef50_Q07938 Multicopy enhancer of UAS2 n=12 Tax=Saccharomyce...   171   3e-41
UniRef50_B8P408 Predicted protein n=2 Tax=Agaricomycetes RepID=B...   169   9e-41
UniRef50_Q1CZV1 Phosphorylase, family 2 n=5 Tax=Myxococcaceae Re...   169   1e-40
UniRef50_C9ZU87 Methylthioadenosine phosphorylase, putative n=8 ...   168   1e-40
UniRef50_Q11FN7 Methylthioadenosine phosphorylase n=1 Tax=Chelat...   168   3e-40
UniRef50_A0B8I0 Methylthioadenosine phosphorylase n=1 Tax=Methan...   167   3e-40
UniRef50_Q0CL04 Purine nucleoside phosphorylase n=1 Tax=Aspergil...   167   4e-40
UniRef50_C3Y9W3 Putative uncharacterized protein n=1 Tax=Branchi...   166   1e-39
UniRef50_A7BDZ0 Putative uncharacterized protein n=1 Tax=Actinom...   163   5e-39
UniRef50_Q0SDK3 Probable S-methyl-5-thioadenosine phosphorylase ...   163   7e-39
UniRef50_B3PJG7 Methylthioadenosine phosphorylase n=1 Tax=Cellvi...   161   3e-38
UniRef50_A0L8V4 Methylthioadenosine phosphorylase n=1 Tax=Magnet...   156   5e-37
UniRef50_D1J9Q0 Putative uncharacterized protein n=2 Tax=uncultu...   155   2e-36
UniRef50_Q2LVG5 Phosphorylase family 2 protein n=1 Tax=Syntrophu...   152   1e-35
UniRef50_Q2FR33 Methylthioadenosine phosphorylase n=1 Tax=Methan...   151   2e-35
UniRef50_A9B0Q9 Purine phosphorylase family 2 n=1 Tax=Herpetosip...   150   4e-35
UniRef50_B1ZY09 Purine phosphorylase family 2 n=2 Tax=Opitutacea...   148   3e-34
UniRef50_C0W926 Purine-nucleoside phosphorylase n=1 Tax=Actinomy...   147   3e-34
UniRef50_B0TI52 Purine nucleoside phosphorylase n=8 Tax=Clostrid...   146   7e-34
UniRef50_A2SSB6 Methylthioadenosine phosphorylase n=2 Tax=Methan...   145   2e-33
UniRef50_UPI0000D5796F PREDICTED: similar to purine nucleoside p...   144   3e-33
UniRef50_Q67R93 Methylthioadenosine phosphorylase n=1 Tax=Symbio...   144   3e-33
UniRef50_UPI0000E4A236 PREDICTED: similar to GTP-binding protein...   136   1e-30
UniRef50_B9K7V5 Purine nucleoside phosphorylase n=1 Tax=Thermoto...   134   3e-30
UniRef50_B5JG81 Phosphorylases family 2 n=1 Tax=Verrucomicrobiae...   133   8e-30
UniRef50_C1HCE7 Purine nucleoside phosphorylase n=1 Tax=Paracocc...   130   4e-29
UniRef50_Q4P1A5 Putative uncharacterized protein n=1 Tax=Ustilag...   130   5e-29
UniRef50_UPI0001926077 PREDICTED: similar to nucleoside phosphor...   129   8e-29
UniRef50_A7I6C4 Purine phosphorylase, family 2 n=2 Tax=Genera in...   128   3e-28
UniRef50_D0NYY4 Putative uncharacterized protein n=1 Tax=Phytoph...   121   2e-26
UniRef50_Q9RKG9 Putative phosphorylase n=1 Tax=Streptomyces coel...   119   1e-25
UniRef50_UPI000038263C COG0005: Purine nucleoside phosphorylase ...    96   1e-18
UniRef50_UPI000187D203 hypothetical protein MPER_09068 n=1 Tax=M...    75   3e-12

Sequences not found previously or not previously below threshold:

UniRef50_A4X3Q9 Methylthioadenosine phosphorylase n=8 Tax=Actino...   184   3e-45
UniRef50_Q09438 Putative S-methyl-5'-thioadenosine phosphorylase...   183   4e-45
UniRef50_C5TP90 Methylthioadenosine phosphorylase n=5 Tax=Neisse...   183   4e-45
UniRef50_Q2BRI1 Methylthioadenosine phosphorylase n=1 Tax=Neptun...   175   2e-42
UniRef50_C5C002 Methylthioadenosine phosphorylase n=37 Tax=Actin...   171   2e-41
UniRef50_Q09816 Uncharacterized protein C16C9.02c n=49 Tax=cellu...   171   3e-41
UniRef50_A2QWR2 Contig An11c0240, complete genome n=24 Tax=Leoti...   169   1e-40
UniRef50_B8NP67 5'-methylthioadenosine phosphorylase (Meu1), put...   160   4e-38
UniRef50_UPI0000164ED7 purine nucleoside phosphorylase n=1 Tax=H...   155   1e-36
UniRef50_Q7TP15 Cc1-6 n=9 Tax=Coelomata RepID=Q7TP15_RAT              147   5e-34
UniRef50_Q2RHE2 Purine phosphorylase, family 2 n=1 Tax=Moorella ...   143   5e-33
UniRef50_C9KQI5 Phosphorylase, family 2 n=1 Tax=Mitsuokella mult...   136   9e-31
UniRef50_A4IXW9 Phosphorylase family 2/alpha-beta hydrolase fold...   132   2e-29
UniRef50_UPI0001C31DF7 S-methyl-5''''-thioadenosine phosphorylas...   128   2e-28
UniRef50_C7DHY9 S-methyl-5-thioadenosine phosphorylase n=1 Tax=C...   115   1e-24
UniRef50_A8RJ25 Putative uncharacterized protein n=1 Tax=Clostri...   115   2e-24
UniRef50_Q2S0L6 5'-methylthioadenosine phosphorylase II n=1 Tax=...   108   2e-22
UniRef50_C5KDS7 Methylthioadenosine/purine nucleoside phosphoryl...   107   3e-22
UniRef50_Q67R94 Methylthioadenosine phosphorylase n=1 Tax=Symbio...   106   8e-22
UniRef50_UPI00016A8371 5''''-methylthioadenosine phosphorylase n...   104   4e-21
UniRef50_C8SNV7 Purine or other phosphorylase family 1 n=2 Tax=M...    97   5e-19
UniRef50_A9WPZ3 5'-methylthioadenosine phosphorylase n=1 Tax=Ren...    87   7e-16
UniRef50_P23139 Uncharacterized 25.8 kDa protein in petC 3'regio...    86   2e-15
UniRef50_C0W509 Possible purine-nucleoside phosphorylase n=1 Tax...    83   1e-14
UniRef50_Q9NRK7 MTAP (Fragment) n=2 Tax=Homo sapiens RepID=Q9NRK...    73   9e-12
UniRef50_A9WPZ4 5'-methylthioadenosine phosphorylase n=1 Tax=Ren...    69   2e-10
UniRef50_A4GI77 Possible methylthioadenosine phosphorylase n=1 T...    65   2e-09
UniRef50_A9B0R0 Methylthioadenosine phosphorylase n=1 Tax=Herpet...    61   4e-08
UniRef50_C0QJ87 Putative purine nucleoside phosphorylase n=1 Tax...    58   4e-07
UniRef50_A0LI68 Purine and other phosphorylases, family 1 n=1 Ta...    57   9e-07
UniRef50_C8QZD7 Purine or other phosphorylase family 1 n=1 Tax=D...    53   1e-05
UniRef50_A6RV57 Putative uncharacterized protein n=1 Tax=Botryot...    52   2e-05
UniRef50_D1AJ63 Purine or other phosphorylase family 1 n=3 Tax=B...    51   3e-05

>UniRef50_P45563 Xanthosine phosphorylase n=57 Tax=cellular organisms
           RepID=XAPA_ECOLI
          Length = 277

 Score =  385 bits (990), Expect = e-106,   Method: Composition-based stats.
 Identities = 277/277 (100%), Positives = 277/277 (100%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS
Sbjct: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS
Sbjct: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG
Sbjct: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
           FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM
Sbjct: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA
Sbjct: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277


>UniRef50_B5R3U9 Xanthosine phosphorylase n=53 Tax=Enterobacteriaceae
           RepID=B5R3U9_SALEP
          Length = 307

 Score =  373 bits (957), Expect = e-102,   Method: Composition-based stats.
 Identities = 246/277 (88%), Positives = 258/277 (93%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           M    FSHNP +CIDII  +KP FTPRVAFILGSGLGALADQIE+AVAISYEKLPGFPVS
Sbjct: 31  MPHALFSHNPEYCIDIIHAHKPAFTPRVAFILGSGLGALADQIEDAVAISYEKLPGFPVS 90

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           TVHGHAGELVLGHL GVPV CMKGRGHFYEGRGM +MTDAIRT KLLGCE+LFCTNAAGS
Sbjct: 91  TVHGHAGELVLGHLAGVPVACMKGRGHFYEGRGMAVMTDAIRTLKLLGCEVLFCTNAAGS 150

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           LRPEVG GSLVAL DHINTMPGTPMVG NDDR+G+RFFSLANAYDA+YRA+LQ VA EEG
Sbjct: 151 LRPEVGPGSLVALSDHINTMPGTPMVGPNDDRYGDRFFSLANAYDADYRAMLQSVAAEEG 210

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
           FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHC LKVVAVSAITN+
Sbjct: 211 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCGLKVVAVSAITNL 270

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           AEGL DVKLSHAQTLAAAELS+QNFINLICGFLRK+A
Sbjct: 271 AEGLGDVKLSHAQTLAAAELSRQNFINLICGFLRKLA 307


>UniRef50_P77834 Purine nucleoside phosphorylase 1 n=41 Tax=Bacilli RepID=PUNA_BACST
          Length = 274

 Score =  368 bits (944), Expect = e-100,   Method: Composition-based stats.
 Identities = 120/265 (45%), Positives = 164/265 (61%), Gaps = 1/265 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
               +K   P  +P++  ILGSGLG LAD+IE A+ I Y  +P FPVSTV GHAG+LV G
Sbjct: 9   AAQFLKEKFPT-SPQIGLILGSGLGVLADEIEQAIKIPYSDIPNFPVSTVEGHAGQLVYG 67

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L+G  VV M+GR H+YEG     +T  +R  K LG E L  TNAAG +      G L+ 
Sbjct: 68  QLEGATVVVMQGRFHYYEGYSFDKVTFPVRVMKALGVEQLIVTNAAGGVNESFEPGDLMI 127

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN M G P++G ND   G RF  ++ AY    R L + VA + G  + EGV+V+  
Sbjct: 128 ISDHINNMGGNPLIGPNDSALGVRFPDMSEAYSKRLRQLAKDVANDIGLRVREGVYVANT 187

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP +ET AEIRM++++GGD VGMS VPEVI ARH  ++V+ +S I+NMA G+ D  L+H 
Sbjct: 188 GPAYETPAEIRMIRVMGGDAVGMSTVPEVIVARHAGMEVLGISCISNMAAGILDQPLTHD 247

Query: 253 QTLAAAELSKQNFINLICGFLRKIA 277
           + +   E  K +F+  +   +R +A
Sbjct: 248 EVIETTEKVKADFLRFVKAIVRNMA 272


>UniRef50_Q2B6A0 Purine nucleoside phosphorylase n=12 Tax=Bacilli RepID=Q2B6A0_9BACI
          Length = 273

 Score =  363 bits (931), Expect = 5e-99,   Method: Composition-based stats.
 Identities = 117/263 (44%), Positives = 162/263 (61%), Gaps = 1/263 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
               +K    + TP++  ILGSGLG LAD+IE  V I Y ++P FPVSTV GHAG+LV G
Sbjct: 9   AAQFLKEKYGE-TPKIGLILGSGLGVLADEIEQPVKIPYNEIPDFPVSTVEGHAGQLVFG 67

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L GV  V M+GR H+YEG     +T  +R  K LG E+L  TNAAG +      G L+ 
Sbjct: 68  LLNGVQAVAMQGRFHYYEGYSFDKVTFPVRVMKELGVEILIVTNAAGGVNESFAPGDLML 127

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN M   P++G ND + G RF  ++ AY  + R   +++A +    + EGV+V   
Sbjct: 128 ISDHINNMGSNPLIGPNDSKLGVRFPDMSEAYSRDLRQQAREIAGKLNISIQEGVYVGNT 187

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP +ET AE+RM++ +GGD VGMS VPEVI ARH  LKV+ +S I+NMA G+ D  L+H 
Sbjct: 188 GPTYETPAEVRMLRTMGGDAVGMSTVPEVIVARHAGLKVLGISCISNMAAGILDQPLNHE 247

Query: 253 QTLAAAELSKQNFINLICGFLRK 275
           + +   E  K NF++ +   +R+
Sbjct: 248 EVIETTEKVKANFLSYVKELVRQ 270


>UniRef50_P46354 Purine nucleoside phosphorylase 1 n=69 Tax=Bacteria
           RepID=PUNA_BACSU
          Length = 271

 Score =  360 bits (925), Expect = 2e-98,   Method: Composition-based stats.
 Identities = 120/263 (45%), Positives = 169/263 (64%), Gaps = 1/263 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
               IK   P+ +P++  ILGSGLG LAD+IEN V + YE +P FPVSTV GHAG+LVLG
Sbjct: 8   AAAFIKQNLPE-SPKIGLILGSGLGILADEIENPVKLKYEDIPEFPVSTVEGHAGQLVLG 66

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L+GV V+ M+GR HFYEG  M  +T  +R  K LG E L  TNAAG +  E  AG L+ 
Sbjct: 67  TLEGVSVIAMQGRFHFYEGYSMEKVTFPVRVMKALGVEALIVTNAAGGVNTEFRAGDLMI 126

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN M   P++G N+  FG RF  +++AYD +  +L +K+AK+   P+ +GV+ +  
Sbjct: 127 ITDHINFMGTNPLIGPNEADFGARFPDMSSAYDKDLSSLAEKIAKDLNIPIQKGVYTAVT 186

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP++ET AE+R ++ +G D VGMS VPEVI A H  ++V+ +S I+N A G+ D  LSH 
Sbjct: 187 GPSYETPAEVRFLRTMGSDAVGMSTVPEVIVANHAGMRVLGISCISNAAAGILDQPLSHD 246

Query: 253 QTLAAAELSKQNFINLICGFLRK 275
           + +   E  K  F+ L+   + +
Sbjct: 247 EVMEVTEKVKAGFLKLVKAIVAQ 269


>UniRef50_Q65HU0 PunA n=9 Tax=Firmicutes RepID=Q65HU0_BACLD
          Length = 271

 Score =  359 bits (923), Expect = 4e-98,   Method: Composition-based stats.
 Identities = 125/264 (47%), Positives = 165/264 (62%), Gaps = 1/264 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
             D IK+ K +  P V  ILGSGLG LAD+IE+AV I YE +P FPVSTV GHAG+LV+G
Sbjct: 8   AADYIKS-KTEIKPAVGLILGSGLGVLADEIEDAVRIKYEDIPDFPVSTVEGHAGQLVIG 66

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L+ V VV M+GR HFYEG  M  +T  +R  K LG E L  TNAAG +      G L+ 
Sbjct: 67  RLENVQVVAMQGRFHFYEGYSMDKVTFPVRVMKELGIETLIVTNAAGGVNESFRPGDLMI 126

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN M   P++G ND   G RF  +++AYD E R L +K A+E    + EGV+ +  
Sbjct: 127 ISDHINYMGTNPLIGPNDSSLGVRFPDMSSAYDKELRLLAKKTAEELNISVQEGVYTAVT 186

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP +ET AE+R ++ IG D VGMS VPEVI A+H  L+V+ +S I+N A G+ D  LSH 
Sbjct: 187 GPTYETPAEVRFLRTIGSDAVGMSTVPEVIVAKHAGLRVLGISCISNAAAGILDQPLSHD 246

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           + +   E  K +F+  +   + KI
Sbjct: 247 EVIEVTEKVKADFLRFVKAAVAKI 270


>UniRef50_A7GSB0 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=114 Tax=Bacteria RepID=A7GSB0_BACCN
          Length = 273

 Score =  359 bits (921), Expect = 8e-98,   Method: Composition-based stats.
 Identities = 123/258 (47%), Positives = 167/258 (64%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
             K   TP+V  ILGSGLG LAD+IENAV + Y ++P FPVSTV GHAG+LV G LQGV 
Sbjct: 14  KEKFQETPKVGLILGSGLGVLADEIENAVKVPYSEIPEFPVSTVEGHAGQLVFGTLQGVT 73

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           VV M+GR H+YEG  M  +T  +R  K LG E +  TNAAG +      G L+ + DHIN
Sbjct: 74  VVAMQGRFHYYEGYDMQKVTFPVRVMKELGVETVVVTNAAGGVNTSFEPGDLMLISDHIN 133

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFET 198
            M   P++G ND   G RF  ++ +Y  E R ++++VA+E    + EGV+V+  GP +ET
Sbjct: 134 FMGHNPLIGPNDAEMGVRFPDMSESYTKELRVMVKQVAEELNIKVQEGVYVAMTGPVYET 193

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
            AEIRM++ +GGD VGMS VPEVI ARH  +KV+ +S I+NMA G+ D  L H + +   
Sbjct: 194 PAEIRMLRTLGGDAVGMSTVPEVIVARHAGMKVLGISCISNMAAGILDQPLHHDEVIETT 253

Query: 259 ELSKQNFINLICGFLRKI 276
           E  K NF+ L+   ++++
Sbjct: 254 ERVKANFLALVKAIVKQM 271


>UniRef50_B1YM96 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=8 Tax=Bacteria RepID=B1YM96_EXIS2
          Length = 270

 Score =  354 bits (910), Expect = 1e-96,   Method: Composition-based stats.
 Identities = 117/258 (45%), Positives = 162/258 (62%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
             K    P +  ILGSGLG LAD IEN +AI Y  +P FPVSTV GHAG+LV G L+G  
Sbjct: 13  ESKMQAKPEIGLILGSGLGVLADDIENPIAIPYSDIPNFPVSTVEGHAGQLVFGTLEGKQ 72

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           VV M+GR HFYEG  M ++T  +R  K +G E L  TNAAG+       G L+ + DHIN
Sbjct: 73  VVAMQGRFHFYEGYSMEMVTFPVRVMKAIGVETLIVTNAAGACNEAFEPGDLMLITDHIN 132

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFET 198
                P++G N D  G RF  ++  YDAE   L Q+ A E G  + +GV+    GP +ET
Sbjct: 133 FFGTNPLIGKNVDEMGPRFPDMSKPYDAELLRLAQETADELGINVRQGVYFGNTGPTYET 192

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
            AE+++ +++GGDVVGMS VPEVI ARH D++V+ +S ++NMA G+ D  L H + +   
Sbjct: 193 PAEVKLARLLGGDVVGMSTVPEVIVARHSDMRVLGISCVSNMAAGILDQPLHHDEVIETT 252

Query: 259 ELSKQNFINLICGFLRKI 276
           E  + +F++L+ G ++K+
Sbjct: 253 ERVRAHFLSLVRGSIKKM 270


>UniRef50_A3DEQ4 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=8 Tax=Firmicutes RepID=A3DEQ4_CLOTH
          Length = 275

 Score =  344 bits (883), Expect = 2e-93,   Method: Composition-based stats.
 Identities = 110/262 (41%), Positives = 159/262 (60%), Gaps = 1/262 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
               IK    + TP +A +LGSGLG LAD+IEN V I Y+ +P FPV+TV GHAG+ V G
Sbjct: 11  TASFIKRIIKE-TPEIAIVLGSGLGPLADEIENKVEIDYKDVPNFPVTTVEGHAGKFVYG 69

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L+   V+ MKGR H YEG  ++ +   +R FK+LG   L  TNA+G +      G L+ 
Sbjct: 70  ILENRRVIAMKGRFHHYEGYDVSQIVFPVRVFKMLGINNLIVTNASGGINRSFRPGDLMI 129

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           +KDHI+    +P+ G N D FG RF  +  AY+ +   + +K A + G  + EGV+    
Sbjct: 130 IKDHISFFAPSPLRGKNIDEFGLRFPDMCKAYNPKLVEICKKAASDVGVDVKEGVYAFTQ 189

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP +ET AEIR + I+G D VGMS VPEVI+ARH ++ ++ +S ITNMA G+ D  L+H 
Sbjct: 190 GPMYETPAEIRALGILGADAVGMSTVPEVIAARHANMNILGISCITNMAAGILDQPLTHE 249

Query: 253 QTLAAAELSKQNFINLICGFLR 274
           + +  A+ ++  F+ L+   + 
Sbjct: 250 EVMKTAKEAENKFVRLVKRVIS 271


>UniRef50_A6BDL0 Putative uncharacterized protein n=1 Tax=Dorea longicatena DSM
           13814 RepID=A6BDL0_9FIRM
          Length = 270

 Score =  344 bits (883), Expect = 2e-93,   Method: Composition-based stats.
 Identities = 108/264 (40%), Positives = 159/264 (60%), Gaps = 1/264 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
           C+  I+  K DF P  A ILGSGLG  A++I+    + Y  +  FPVSTV GH G+ V G
Sbjct: 8   CLKSIRE-KTDFKPEKAVILGSGLGDYAEKIKIEKIVKYTDIEDFPVSTVQGHKGQFVFG 66

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
           +++ VPVV M+GR H+YEG  M  +    R   ++G + +  TNAAG + P    G  + 
Sbjct: 67  YVEDVPVVLMQGRVHYYEGYPMQDVVLPTRLMGMMGAKKILLTNAAGGVNPSFRPGDFML 126

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           +KDHI T   +P++G N +  G RF  ++  Y  + + +++K AK+ G PL EGV+V   
Sbjct: 127 IKDHITTAVPSPLIGPNIEELGTRFPDMSEVYSKKLQDIIRKSAKDCGIPLQEGVYVQLT 186

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GPN+ET AEIRM++  G D VGMS   E ++ARH  ++V  +S ITNMA G+S+ KL+HA
Sbjct: 187 GPNYETPAEIRMVRSWGADAVGMSTACEAMAARHMGMEVCGISCITNMAAGVSNAKLNHA 246

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           +    A+   ++F  L+   +  I
Sbjct: 247 EVQETADRVAKDFEKLVTDVIAAI 270


>UniRef50_A9KIZ4 Inosine guanosine and xanthosine phosphorylase family n=6
           Tax=cellular organisms RepID=A9KIZ4_CLOPH
          Length = 274

 Score =  339 bits (870), Expect = 6e-92,   Method: Composition-based stats.
 Identities = 103/258 (39%), Positives = 147/258 (56%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
             K +  P+V  +LGSGLG L D IE    ISYE +P FP STV GH G LV G + GV 
Sbjct: 16  QSKNNLKPKVGVVLGSGLGDLIDVIEEIEYISYEDIPNFPKSTVIGHQGRLVFGKINGVD 75

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           ++ M+GR H++EG  M  +   I   K LG E L  TNA G +  +   G+L+ + D IN
Sbjct: 76  ILAMQGRFHYFEGYTMKEVAYPIFVMKQLGIEQLILTNACGGINTDFQPGTLMIINDFIN 135

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFET 198
            +   P++G+ND+RFG RF  ++  Y  +     + +A E G    EGV+  + GP +ET
Sbjct: 136 LVSDNPLIGVNDERFGTRFPDMSEPYKLDLIDKAKNIANEMGIEYKEGVYAGFMGPYYET 195

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
           AAEIRM++  G D VGMS VPE I+A +  + V+ +S ITNMA G+   K SH + +  A
Sbjct: 196 AAEIRMIKNHGADAVGMSTVPETIAANYLGIDVLGISCITNMATGIQKHKHSHERVVETA 255

Query: 259 ELSKQNFINLICGFLRKI 276
           + +  N    +   +  +
Sbjct: 256 QKASVNLSKWVAKIIENM 273


>UniRef50_C1F7J2 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Acidobacterium capsulatum ATCC 51196
           RepID=C1F7J2_ACIC5
          Length = 284

 Score =  339 bits (869), Expect = 8e-92,   Method: Composition-based stats.
 Identities = 110/277 (39%), Positives = 163/277 (58%), Gaps = 1/277 (0%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           MS +      +     I+   P   P+VA +LGSGLGA A  + N+  + + + P FPVS
Sbjct: 1   MSSLSIFSETIEATACIRKRSP-LQPKVAVVLGSGLGAFAGSLTNSKCMRFSEAPHFPVS 59

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
            V GH+G + +G     PV+ M+GR H YEG   + +   +R  K LG E +  TNAAG 
Sbjct: 60  NVQGHSGRIHIGQCGDTPVLVMQGRVHAYEGYKPSQVAFPVRVMKQLGIEQVIVTNAAGG 119

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           +R  +  G LV ++DHIN     P+ G+N++RFG RFF + NAY    R L   VA++ G
Sbjct: 120 IREGLQPGELVLIEDHINLTGYNPLCGVNEERFGPRFFDMTNAYSPRLRKLAHSVAEQHG 179

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
             L EGV++   GP+FET AEIR  + +G D+VGMS V EVI+ARH  L+V+ +S +TN+
Sbjct: 180 HSLKEGVYIGVLGPSFETPAEIRAFRSMGADLVGMSTVQEVIAARHMGLEVLGISCVTNL 239

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           A GL + +L+H + L   + ++     L+ G + ++A
Sbjct: 240 AAGLQNEELTHEEVLETGKRTEAQLTQLLQGVIPQMA 276


>UniRef50_B9MKK7 Inosine guanosine and xanthosine phosphorylase family n=68
           Tax=Bacteria RepID=B9MKK7_ANATD
          Length = 272

 Score =  337 bits (864), Expect = 3e-91,   Method: Composition-based stats.
 Identities = 111/264 (42%), Positives = 160/264 (60%), Gaps = 1/264 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
             + IK+  P+  P +A ILGSGLG+ AD +E  + I Y ++P FPVSTV GH G LV G
Sbjct: 10  ASEFIKSKIPNV-PEIAIILGSGLGSFADTMEEKIEIKYSEIPHFPVSTVKGHKGNLVFG 68

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            ++G  V+  +GR H YEG     +   +R   LLG + L  TNAAG + P +  G L+ 
Sbjct: 69  KVKGREVLAFQGRFHLYEGYNAQEVVFGVRAAGLLGVKNLIVTNAAGGISPLLSPGDLMV 128

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           +KDHIN     P +G   ++FGERFF +  AYD E     + V K+ G    EG++    
Sbjct: 129 IKDHINLSGENPAIGSEAEKFGERFFDMTYAYDREIIEKSKDVYKKNGVDYKEGIYAFLK 188

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP++ET +EIRM++I+G D VGMS V EVI+AR  ++KV  +S ITNMA G+ + KLSH 
Sbjct: 189 GPSYETPSEIRMLKILGADAVGMSTVLEVIAARQMNIKVFGISCITNMAAGILEKKLSHE 248

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           + +  +++ ++ FI +I   +  I
Sbjct: 249 EVIEVSKMVEEKFIKIISDLIEII 272


>UniRef50_A5IBS6 Xanthosine phosphorylase n=5 Tax=Legionella RepID=A5IBS6_LEGPC
          Length = 279

 Score =  334 bits (857), Expect = 2e-90,   Method: Composition-based stats.
 Identities = 122/269 (45%), Positives = 168/269 (62%), Gaps = 1/269 (0%)

Query: 10  PLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGEL 69
           P    + I+   P F P+V  +LGSGLG  A+++E+ VAI YEKLPGFP +TV GH G+L
Sbjct: 11  PHLAAEYIQKTCPSFKPKVGVVLGSGLGQFAEELEDTVAIEYEKLPGFPRTTVQGHGGKL 70

Query: 70  VLGHLQGVPVVCMKGRGHFYEGR-GMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAG 128
           +LG+     V+C++GR H YE       +   +RT KLLGC+    TNA+GSL+ EVG G
Sbjct: 71  ILGYYGSTAVICLQGRAHTYESMENHEAVKTYVRTLKLLGCQYFIATNASGSLKEEVGPG 130

Query: 129 SLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVF 188
            L+ + DHIN  PG P+VG NDD FG RF+ L NAYD   R  L  +A+     L +GV+
Sbjct: 131 ELMLITDHINFQPGNPLVGPNDDEFGPRFYPLDNAYDITMRNALLDIAQRHSIKLHQGVY 190

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK 248
           +S  GPN+ETAAEIR  +++G D VGMS VPEV+ A HC L+V  ++ ITN A GL+   
Sbjct: 191 ISVLGPNYETAAEIRAFKLLGADAVGMSTVPEVLVANHCGLRVAVIATITNYATGLAKTS 250

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKIA 277
            SH   +  A  + +    LI  ++ +++
Sbjct: 251 HSHESVVKMASSAAEKLNTLIKQYILELS 279


>UniRef50_A6NWZ5 Putative uncharacterized protein n=1 Tax=Bacteroides capillosus
           ATCC 29799 RepID=A6NWZ5_9BACE
          Length = 274

 Score =  333 bits (854), Expect = 4e-90,   Method: Composition-based stats.
 Identities = 108/264 (40%), Positives = 157/264 (59%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
             + I++   DFTP+ A +LGSGLG + D +++ + + Y+++P F  ST  GH G+LV G
Sbjct: 11  SAEYIRSKIGDFTPKAAMVLGSGLGFMGDVVKDPIVVPYKEIPHFKASTAPGHKGQLVFG 70

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
           +L+  PV  M+GR H YEG     ++ A+R  +LLG + L  TNAAG +R +  AG L+ 
Sbjct: 71  YLEDKPVAVMQGRMHHYEGYSFEDVSYAVRVLRLLGADTLIVTNAAGCVRTDWQAGDLML 130

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHI     +P+ G N   FG RF   ++ Y    R L ++ A E G  L EGV+    
Sbjct: 131 ITDHIKMFSESPLRGENMPEFGVRFPDASSLYTPALRTLAREAAAELGIELREGVYFYCY 190

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP +ET AE+R  +I+GGD VGMS  PEVI A HC ++V+  + ++NMA G+ D  LS  
Sbjct: 191 GPQYETPAEVRAARILGGDAVGMSTAPEVIVAGHCGMQVLGFTLLSNMAAGILDQPLSEQ 250

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           + L AAE  K  F  L+   L+K+
Sbjct: 251 EVLDAAEACKDKFSRLVLACLKKL 274


>UniRef50_B8HVY6 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Cyanothece sp. PCC 7425 RepID=B8HVY6_CYAP4
          Length = 275

 Score =  331 bits (850), Expect = 1e-89,   Method: Composition-based stats.
 Identities = 111/265 (41%), Positives = 158/265 (59%), Gaps = 2/265 (0%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL 71
              + ++ Y     P +  ILGSGLG+ A  ++ ++AI Y  +P FP  TV GH GEL+L
Sbjct: 10  AAAEFLRQY--QIMPDIWVILGSGLGSFASTLKKSLAIPYADIPHFPRPTVAGHGGELIL 67

Query: 72  GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
           G    + V  M+GR H+YEG  +  +T  IR   LLG + L  TNAAG L P+   G L+
Sbjct: 68  GQCGEIAVGVMQGRCHYYEGYSLEQVTFPIRVAGLLGVQRLVITNAAGGLNPDFVPGDLM 127

Query: 132 ALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSY 191
            + DHIN +   P+ G ++ RFG+RF  L  AY A YR L  K A E    L +GV+V+ 
Sbjct: 128 LITDHINLLGMNPLQGRHETRFGDRFLDLTQAYHATYRELALKAAAEMNLTLRQGVYVAL 187

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH 251
           PGP+FET AE+RM++ +GGD VGMS VPEVI  R   ++++ +S ITN+A G+S   ++H
Sbjct: 188 PGPSFETPAEVRMLRALGGDAVGMSTVPEVIVGRQMGVQILGISCITNLAAGISSEPVNH 247

Query: 252 AQTLAAAELSKQNFINLICGFLRKI 276
            + L   E   Q+F  L+   L ++
Sbjct: 248 TEVLEVGEQVSQHFCELLQRTLPRL 272


>UniRef50_Q23U21 Purine nucleoside phosphorylase n=1 Tax=Tetrahymena thermophila
           SB210 RepID=Q23U21_TETTH
          Length = 274

 Score =  330 bits (847), Expect = 3e-89,   Method: Composition-based stats.
 Identities = 97/268 (36%), Positives = 155/268 (57%)

Query: 9   NPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGE 68
           + L     IK+   +  P++A +LGSGLG   D+I++ + I Y  +P F  + V GHAG+
Sbjct: 6   SALEATQFIKSKINNLNPQIAIVLGSGLGNFGDEIQDKIEIPYGDIPHFKKTQVIGHAGK 65

Query: 69  LVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAG 128
           L+ G ++GV +VCM+GR HFYEG  +      I+ FKLL  ++L  TNAAG L     +G
Sbjct: 66  LIFGKVEGVEIVCMQGRYHFYEGHTIQECVFPIKVFKLLNIKILILTNAAGGLNDSYESG 125

Query: 129 SLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVF 188
            L+ ++DHIN +   P++GLN++ FG RF  ++  Y  +     +KV K+    +  G +
Sbjct: 126 DLILIRDHINMLGINPLIGLNEEEFGPRFPDMSITYTPQLLEKAKKVMKDLNISIKTGTY 185

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK 248
               GPN+ET AE++M++    D+VG S V E I A H +++V+ +S ++NM  G+S   
Sbjct: 186 AGLRGPNYETPAEVQMLRTFRADLVGASTVYEAIVASHMNIQVLGISCVSNMGAGISKTP 245

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKI 276
           LSH + +  +   K  F NL+   +  +
Sbjct: 246 LSHQEIIDVSNSIKSKFSNLVKNLIPNL 273


>UniRef50_A9KIE8 Inosine guanosine and xanthosine phosphorylase family n=20
           Tax=Bacteria RepID=A9KIE8_CLOPH
          Length = 286

 Score =  329 bits (843), Expect = 8e-89,   Method: Composition-based stats.
 Identities = 103/259 (39%), Positives = 154/259 (59%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
             K +F P VA +LGSGLG  ADQI+    + Y ++ GFPVSTV GH G  V G+++ VP
Sbjct: 22  QRKINFKPFVALVLGSGLGDYADQIKVEATLDYNEIEGFPVSTVAGHKGRFVFGYVEEVP 81

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           VV M+GR H+YEG  M  +    R  K++G ++LF TNAAG +     AG  + + D I+
Sbjct: 82  VVIMQGRVHYYEGYEMEDVVLPTRLMKMMGAKVLFLTNAAGGVNFNFKAGDFMLITDQIS 141

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFET 198
               +P++G N +  G RF  ++  YD + R +++  AK+ G  L EGV++   GPNFE+
Sbjct: 142 NFVPSPLIGPNIEELGLRFCDMSEVYDKDLREVIRNSAKDIGMELQEGVYIQLSGPNFES 201

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
            AE++M +++G D VGMS   E I+A H  +K+  +S I+N+  G+++  LSH +    A
Sbjct: 202 PAEVKMCRLLGADAVGMSTACEAITANHMGMKICGISCISNLGCGMTEEPLSHIEVQETA 261

Query: 259 ELSKQNFINLICGFLRKIA 277
           +     F  LI   +R IA
Sbjct: 262 DRVAPLFKQLITTSIRNIA 280


>UniRef50_P00491 Purine nucleoside phosphorylase n=19 Tax=Coelomata RepID=PNPH_HUMAN
          Length = 289

 Score =  328 bits (841), Expect = 1e-88,   Method: Composition-based stats.
 Identities = 112/271 (41%), Positives = 152/271 (56%), Gaps = 8/271 (2%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
             + + ++     P+VA I GSGLG L D++  A    Y ++P FP STV GHAG LV G
Sbjct: 13  TAEWLLSH-TKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFG 71

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L G   V M+GR H YEG  +  +T  +R F LLG + L  TNAAG L P+   G ++ 
Sbjct: 72  FLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIML 131

Query: 133 LKDHIN---TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG--FPLTEGV 187
           ++DHIN        P+ G ND+RFG+RF ++++AYD   R       K+ G    L EG 
Sbjct: 132 IRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGT 191

Query: 188 FVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM--AEGLS 245
           +V   GP+FET AE R++Q +G D VGMS VPEVI ARHC L+V   S ITN    +  S
Sbjct: 192 YVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYES 251

Query: 246 DVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
             K +H + LAA + + Q     +   +  I
Sbjct: 252 LEKANHEEVLAAGKQAAQKLEQFVSILMASI 282


>UniRef50_Q1IM44 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=2 Tax=cellular organisms RepID=Q1IM44_ACIBL
          Length = 280

 Score =  328 bits (841), Expect = 1e-88,   Method: Composition-based stats.
 Identities = 117/267 (43%), Positives = 164/267 (61%), Gaps = 1/267 (0%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
            +    I +  P   P VA +LGSGLG  A+++     I + ++P FPVST  GHAG LV
Sbjct: 11  EYAARFIGSKCP-VRPNVAVVLGSGLGDFANELAQPSTIPFGEIPHFPVSTAIGHAGNLV 69

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
           +G+  G+ +  M+GR HFYEG         +R    LG + +  TNAAG + P+ G G+L
Sbjct: 70  IGNFVGLSLAVMQGRAHFYEGNTFAQAAFPMRVLHQLGVKAVVLTNAAGGINPQYGRGAL 129

Query: 131 VALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVS 190
           V ++DHIN M G+P++G NDDRFG RF  +  AYD EYR + +  AK    P  EG++ +
Sbjct: 130 VMVRDHINMMGGSPLIGPNDDRFGPRFPDMTYAYDREYRKIAEAEAKRLDIPYYEGIYAA 189

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
             GP++ET AEI+M+  +G D+VGMS VPEVI ARH D++V+A+S +TNMA GLS   ++
Sbjct: 190 MHGPSYETPAEIQMLARMGADLVGMSTVPEVIVARHMDVRVLAISCVTNMAAGLSGEAIN 249

Query: 251 HAQTLAAAELSKQNFINLICGFLRKIA 277
           H + L      K  F+ L+   L KIA
Sbjct: 250 HEEVLETGRRVKDTFLALLRAVLPKIA 276


>UniRef50_B6J4B4 Xanthosine phosphorylase n=8 Tax=Gammaproteobacteria
           RepID=B6J4B4_COXB1
          Length = 273

 Score =  327 bits (838), Expect = 3e-88,   Method: Composition-based stats.
 Identities = 126/262 (48%), Positives = 175/262 (66%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +  I+  +PDF P++A +LGSGLG LAD+IE    ISY +LPGF    + GHAG L LG
Sbjct: 8   ALKEIRHRRPDFQPKLAIVLGSGLGDLADEIEEPTVISYHELPGFHKPNIEGHAGNLYLG 67

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            ++GVPV C++GR H+YEG     +   IRT KLLGCE+   TNAAGSL   +  GSL+ 
Sbjct: 68  KIKGVPVACLRGRAHYYEGADNYAIKTMIRTMKLLGCEIWLATNAAGSLHQRIEPGSLLV 127

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN      +VG N+D FG RF  + +AYD++ RA L K+AK+   PL+EGV++   
Sbjct: 128 INDHINFQFNNVLVGPNEDDFGGRFIGMEDAYDSDLRAQLFKIAKQLQIPLSEGVYIGVL 187

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP FET AEIR  +++G DVVGMS +PEVI ARHCD++V  +S ++N A GL+  K++H 
Sbjct: 188 GPAFETPAEIRAFRLLGADVVGMSTIPEVIVARHCDMRVAVISVVSNFAAGLTHEKVTHE 247

Query: 253 QTLAAAELSKQNFINLICGFLR 274
           QTL   +L+ ++   L+  F++
Sbjct: 248 QTLRGVKLATESLKQLVLAFIQ 269


>UniRef50_A6GZM2 Purine-nucleoside phosphorylase n=3 Tax=Bacteroidetes
           RepID=A6GZM2_FLAPJ
          Length = 270

 Score =  326 bits (837), Expect = 4e-88,   Method: Composition-based stats.
 Identities = 106/253 (41%), Positives = 152/253 (60%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           K +F+P    ILGSGLG   D I     + Y ++P FPVSTV GH G LV G +QG  +V
Sbjct: 15  KTNFSPEYGVILGSGLGNFTDDINIEYILPYSEIPNFPVSTVEGHKGALVFGTIQGKKIV 74

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
            M+GR HFYEG  M  +T  +R  K LG E L  +NA+G + P    GS++ +KDHIN M
Sbjct: 75  AMQGRFHFYEGYDMKQVTFPVRVMKYLGVEKLIVSNASGGVNPNYKVGSIILIKDHINMM 134

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAA 200
           P  P+ G ND+RFG RF +++  Y  +     +++A      + +GV++   GP +ET +
Sbjct: 135 PEHPLRGKNDERFGPRFVNMSEPYSRKMIVKAKEIASYLDIQVQDGVYLGLQGPTYETLS 194

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAEL 260
           E +M++ +G D VGMS VPEVI ARH +L+   +S IT+M    S   +SHA+ L AA+ 
Sbjct: 195 EYKMVKNVGADCVGMSTVPEVIVARHMNLECFGLSIITDMGNEASIETVSHAEVLQAAQK 254

Query: 261 SKQNFINLICGFL 273
           ++ +  NLI   +
Sbjct: 255 AEPHVRNLIKELI 267


>UniRef50_P23492 Purine nucleoside phosphorylase n=47 Tax=Metazoa RepID=PNPH_MOUSE
          Length = 289

 Score =  325 bits (834), Expect = 1e-87,   Method: Composition-based stats.
 Identities = 110/273 (40%), Positives = 150/273 (54%), Gaps = 8/273 (2%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
                 +  +  ++ P+VA I GSGLG L   ++ A    Y ++P FP STV GHAG LV
Sbjct: 11  ETTAKWLLQH-TEYRPQVAVICGSGLGGLTAHLKEAQIFDYNEIPNFPQSTVQGHAGRLV 69

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
            G L G   V M+GR H YEG  ++ +T  +R F LLG E L  TNAAG L P    G +
Sbjct: 70  FGLLNGRCCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVETLVVTNAAGGLNPNFEVGDI 129

Query: 131 VALKDHIN---TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG--FPLTE 185
           + ++DHIN        P+ G ND+RFG RF ++++AYD + R       K+ G    L E
Sbjct: 130 MLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFTAWKQMGEQRKLQE 189

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           G +V   GPNFET AE R+++++G D VGMS VPEVI ARHC L+V   S ITN      
Sbjct: 190 GTYVMLAGPNFETVAESRLLKMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDY 249

Query: 246 D--VKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           +   K +H + L A + + Q     +   +  I
Sbjct: 250 ENLEKANHMEVLDAGKAAAQTLERFVSILMESI 282


>UniRef50_Q6MGR6 Pnp protein n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MGR6_BDEBA
          Length = 280

 Score =  323 bits (829), Expect = 3e-87,   Method: Composition-based stats.
 Identities = 98/261 (37%), Positives = 147/261 (56%), Gaps = 1/261 (0%)

Query: 16  IIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQ 75
            I+T K    P++  +LGSGLGA   ++E    I Y+ +P F   TV GH+G L+ G + 
Sbjct: 21  YIRT-KTSAKPKIGVVLGSGLGAFVKEVEVETTIPYKDIPHFSPPTVEGHSGNLIFGKIN 79

Query: 76  GVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKD 135
           G  +  ++GR H+YEG  M  +    RT  +LG E L  TN+AG     + AG  + ++D
Sbjct: 80  GQSIAILQGRNHYYEGHSMESVVFPTRTLAMLGVETLILTNSAGGFGENMQAGDFMVIED 139

Query: 136 HINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPN 195
           HIN M   P++G N    G RF  +  AYD     +++ V  ++G    +GV+    GP 
Sbjct: 140 HINLMGTNPLMGPNIKELGPRFPDMTEAYDKRLIQIMEDVLMKQGTRYHKGVYCGVSGPT 199

Query: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL 255
           +ET +E+R +++IGG  VGMS VPE I+A H  L+V A+S ITN+A G+S  KLSH +  
Sbjct: 200 YETPSEVRYLKLIGGKAVGMSTVPETIAANHLGLRVAALSCITNLAAGISSQKLSHNEVT 259

Query: 256 AAAELSKQNFINLICGFLRKI 276
             A+  +  F + +  F+  I
Sbjct: 260 ETAKQVEMQFSSFLREFIAHI 280


>UniRef50_C7M8V2 Inosine guanosine and xanthosine phosphorylase family n=3
           Tax=Flavobacteriaceae RepID=C7M8V2_CAPOD
          Length = 275

 Score =  323 bits (829), Expect = 3e-87,   Method: Composition-based stats.
 Identities = 108/262 (41%), Positives = 154/262 (58%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
              II++Y  + TP  A ILGSGL  L D++E    I Y  +P FP STV GH G+L+ G
Sbjct: 11  TARIIQSYITEHTPEFAIILGSGLNKLEDEVEVISEIKYNNIPNFPKSTVEGHKGKLIYG 70

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            ++   V+ M GR H+YEG  M  +T  IR F  LG + L  +NA+G + P    G ++ 
Sbjct: 71  KIENRYVLMMAGRVHYYEGYTMQEVTFPIRVFAQLGIKRLIVSNASGGVNPNFSIGDVMV 130

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           ++DHIN  P  P+ G N D FG RF  ++  Y       L+K+AK+    L +GV+V   
Sbjct: 131 IRDHINLFPEHPLRGKNLDLFGARFPDMSKPYSQAMITELEKIAKKHKIKLQKGVYVGLQ 190

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP+FET AE  M++I+GGD VGMS VPEVI ARH +++V A+S IT++        +SH 
Sbjct: 191 GPSFETPAEYGMVRILGGDAVGMSTVPEVIVARHQNMEVCALSVITDLGGPDISPDVSHE 250

Query: 253 QTLAAAELSKQNFINLICGFLR 274
           + L AA ++  N I L+   ++
Sbjct: 251 EVLNAANIAMPNVILLVKNLIK 272


>UniRef50_C9LGF9 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Prevotella tannerae ATCC 51259
           RepID=C9LGF9_9BACT
          Length = 291

 Score =  322 bits (827), Expect = 6e-87,   Method: Composition-based stats.
 Identities = 99/264 (37%), Positives = 152/264 (57%), Gaps = 2/264 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
             + I+ +     P+ A +LG+GLG LA +I+      Y+ +P FPVSTV GH+G L+ G
Sbjct: 29  TAEWIQAH-TALRPQTAIVLGTGLGKLAQEIDVVDEFPYKDIPNFPVSTVEGHSGRLIFG 87

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
           HL G P++ ++GR H+YEG  M  +T   R    LG + LF +NA+G   P+   G L+ 
Sbjct: 88  HLGGKPIMALEGRFHYYEGYTMQEVTFPERVMYALGIKNLFLSNASGGTNPDFEIGDLML 147

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN  P  P+ G N    G RF  ++ AYD  +    + +A+E+G  + EGV+++  
Sbjct: 148 ITDHINFQPEHPLHGPNIPT-GPRFPDMSEAYDRAFLEAARNIAREKGIKVVEGVYLADQ 206

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP +ET AE +M +++G D VGMS VPEVI ARHC ++   +S IT++      V++SH 
Sbjct: 207 GPTYETPAEYKMYRLLGADAVGMSTVPEVIVARHCGIRCFGISIITDLGVEGKIVEVSHE 266

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           +   AA   +     +    ++KI
Sbjct: 267 EVQKAANAVQPLMAEIFRELIKKI 290


>UniRef50_A7S700 Predicted protein n=3 Tax=cellular organisms RepID=A7S700_NEMVE
          Length = 295

 Score =  322 bits (827), Expect = 6e-87,   Method: Composition-based stats.
 Identities = 105/266 (39%), Positives = 144/266 (54%), Gaps = 8/266 (3%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
             +  + P +  I GSGL +L D +     I YEK+P FP STV GH G+LV G L G  
Sbjct: 29  RNQTSYQPTIGVICGSGLSSLGDLVTEKTVIPYEKIPQFPRSTVPGHQGQLVFGRLNGTT 88

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           VV M+GR H YEG     +T  +R    LG + L  TNAAG LR +   G ++ +KDHIN
Sbjct: 89  VVMMQGRTHLYEGYDPGQITLPVRVMVHLGIKHLVVTNAAGGLRQDWNVGDIMVIKDHIN 148

Query: 139 ---TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPG 193
                  +P+ G ND RFG RF +L++AY+ + + L  + A E GF      GV+ +  G
Sbjct: 149 LAGLTGLSPLRGCNDSRFGLRFPALSDAYNKDLQKLALETASELGFADFTRTGVYCAQVG 208

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAE---GLSDVKLS 250
           P FET AE R +Q  G D VGMS V EV  ARH  + V+ +S ITN+A    G ++   +
Sbjct: 209 PCFETPAECRFLQNAGVDAVGMSTVHEVSVARHAGVTVLGISLITNIAVLGYGDNEQPAN 268

Query: 251 HAQTLAAAELSKQNFINLICGFLRKI 276
           H + L        +   L+   L+K+
Sbjct: 269 HDEVLETGRRRASDMQKLVSTILQKL 294


>UniRef50_C1TMH4 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002
           RepID=C1TMH4_9BACT
          Length = 272

 Score =  322 bits (825), Expect = 1e-86,   Method: Composition-based stats.
 Identities = 110/264 (41%), Positives = 157/264 (59%), Gaps = 2/264 (0%)

Query: 15  DIIKTYKPD--FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
           + ++T K    FTP +A +LGSGLGALAD IEN + I YE++P +P+ST  GHAG LV G
Sbjct: 7   EALRTIKDRVGFTPDIAVVLGSGLGALADAIENPIVIPYEEIPHWPMSTAPGHAGRLVAG 66

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
              G  VV M+GR HFYEG  M  +   +R F   G      +NA+G +   +  G +V 
Sbjct: 67  SFCGKSVVAMQGRLHFYEGYQMDQVVFPVRVFGRWGIPYFVASNASGGIGYGLVPGDMVL 126

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN M   P++G N    GERF  ++ AYD +   + ++V++++G     GV+V++ 
Sbjct: 127 IHDHINLMGTNPLIGPNLSELGERFPDMSYAYDRDLLDIAEEVSRDKGITTRRGVYVAFT 186

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP++ET AEIRM + +G DVVGMS VPEVI AR   +KV AVS + N A G++   LS  
Sbjct: 187 GPSYETPAEIRMARTLGADVVGMSTVPEVIVARQAGMKVFAVSCVANYAAGMTASALSEQ 246

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           + L     +      L+ G + K+
Sbjct: 247 EVLDEMGKAAGKLTALVGGVIEKL 270


>UniRef50_D0LL71 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Haliangium ochraceum DSM 14365
           RepID=D0LL71_HALO1
          Length = 275

 Score =  321 bits (823), Expect = 2e-86,   Method: Composition-based stats.
 Identities = 101/260 (38%), Positives = 145/260 (55%)

Query: 17  IKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQG 76
           ++    D  P+V  ILGSGLG+ AD++E+AV++ + ++P    ST  GHAG LV G   G
Sbjct: 2   LRERLGDRKPQVGLILGSGLGSFADELEDAVSVPFGEVPHVLPSTAPGHAGRLVCGTRAG 61

Query: 77  VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDH 136
           V  + M+GR H YEG      T  +R    LG   L  TNAAG +  +   G+ + ++DH
Sbjct: 62  VSCIVMQGRLHLYEGHPAADATFPVRCMIALGARTLLVTNAAGGMHGDWEPGTFMLIRDH 121

Query: 137 INTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNF 196
           IN M   P+ G ND+R G RF  +  AYD   R L  + A E G  L +GV+++  GP +
Sbjct: 122 INMMHDHPLRGPNDERLGPRFPDMTRAYDPALRELALRAADEVGVSLQQGVYLASTGPTY 181

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLA 256
           ET AE+ MM+ +G D  GMS VPEVI ARH   + +  S ITN A G++   L+HA+ + 
Sbjct: 182 ETPAEVMMMRGLGADACGMSTVPEVIVARHMGARCLGFSCITNKAAGITGQPLNHAEVME 241

Query: 257 AAELSKQNFINLICGFLRKI 276
                +     L+   L ++
Sbjct: 242 TGARVRSQLTKLLDAVLAEL 261


>UniRef50_D0NTD2 Purine nucleoside phosphorylase 1 n=5 Tax=cellular organisms
           RepID=D0NTD2_PHYIN
          Length = 363

 Score =  321 bits (823), Expect = 2e-86,   Method: Composition-based stats.
 Identities = 111/273 (40%), Positives = 150/273 (54%), Gaps = 8/273 (2%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
               D ++       P +  + GSGLG L+  +EN   I YE +P FP STV GHAGELV
Sbjct: 86  DTINDFLQERIT-ARPLIGVVCGSGLGGLSKCLENQEVIKYEDIPQFPRSTVEGHAGELV 144

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
            G L G+ VVCM+GR H YEG  M      IR   LLG + L  TNAAG L P+   G L
Sbjct: 145 FGDLDGIRVVCMRGRFHCYEGYAMRETALPIRVMYLLGIKYLLVTNAAGGLNPDFNVGDL 204

Query: 131 VALKDHIN---TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF--PLTE 185
           + + DH+N        P++G ND RFG RF  L+N YD + + L  KVA++ G    + +
Sbjct: 205 MIMNDHLNMPGLSGQHPLIGPNDSRFGARFTPLSNCYDKKLQDLAVKVAEDLGLTHKVRK 264

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA--EG 243
           GV+    GP +ET  E R ++++G D VGMS VPEVI A HC LKV+ +S ITN A   G
Sbjct: 265 GVYCFVSGPTYETPTECRFLRLVGSDAVGMSTVPEVIVAAHCGLKVIGLSLITNKALFPG 324

Query: 244 LSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
                 SH + L   + ++ +    +   + +I
Sbjct: 325 EEREAASHDEVLETVQATQNDIKRYVRDLIAEI 357


>UniRef50_Q95TC1 GH03781p n=13 Tax=cellular organisms RepID=Q95TC1_DROME
          Length = 356

 Score =  319 bits (819), Expect = 5e-86,   Method: Composition-based stats.
 Identities = 112/272 (41%), Positives = 160/272 (58%), Gaps = 10/272 (3%)

Query: 14  IDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH 73
            D I T      P++  I GSGLG+LAD I++     YEK+P FPVSTV GHAG LV+G 
Sbjct: 81  ADFI-TKGSGMRPKIGIICGSGLGSLADMIQDPKIFEYEKIPNFPVSTVEGHAGRLVVGT 139

Query: 74  LQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVAL 133
           L+G  V+ M+GR HFYEG  +   +  +R  KL G E LF TNAAG + P    G ++ +
Sbjct: 140 LEGATVMAMQGRFHFYEGYPLAKCSMPVRVMKLCGVEYLFATNAAGGINPRFAVGDIMLM 199

Query: 134 KDHINTM---PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVF 188
            DH+N +     +P+ G ND RFG RF +L N+Y+ +      ++AK  G    +  GV+
Sbjct: 200 HDHVNMLGFAGNSPLQGPNDPRFGPRFPALVNSYNKDLINKAIEIAKAMGIESNIHVGVY 259

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL---- 244
               GPN+ET AE++ ++++G D VGMS V EVI+ARHCD+KV A S ITN         
Sbjct: 260 SCLGGPNYETIAELKALRMMGVDAVGMSTVHEVITARHCDMKVFAFSLITNKCATEYSDK 319

Query: 245 SDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
            D + +H + +A A+  ++    L+   +R+I
Sbjct: 320 KDDEANHDEVMAVAKNRQKACCELVSRLIREI 351


>UniRef50_UPI0000522022 PREDICTED: similar to nucleoside phosphorylase n=1 Tax=Ciona
           intestinalis RepID=UPI0000522022
          Length = 287

 Score =  318 bits (815), Expect = 1e-85,   Method: Composition-based stats.
 Identities = 105/271 (38%), Positives = 155/271 (57%), Gaps = 7/271 (2%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL 71
              D +K+   +  P++  I GSGL  L + +EN + + Y ++P F  STV GH G+LV 
Sbjct: 16  VSADFLKSKMGNVKPKIGIICGSGLSGLGEVVENKIVVKYSEIPSFVESTVPGHKGQLVF 75

Query: 72  GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
           G + G  VVCM+GR H YEG    ++   +R  KL+G E++  TNAAG + PE   G  +
Sbjct: 76  GQISGKDVVCMQGRFHPYEGYPGWVVGFPLRVMKLIGIEMVLATNAAGGINPEFKVGDFM 135

Query: 132 ALKDHINTM---PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEG 186
            +KDHI+       TP+VG ND  FG RF  + +AYD   R L ++ A + G+   + +G
Sbjct: 136 LIKDHISFTGLAGYTPLVGPNDSSFGPRFPPMNDAYDKNLRTLFKQCASDLGYDDFMRDG 195

Query: 187 VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA--EGL 244
           V+ +  GP++ET AE+R++  +GGD  GMS V EV++ARHC +KV+A S ITN    E  
Sbjct: 196 VYCNVFGPSYETIAELRLLLKLGGDAAGMSTVQEVVTARHCGIKVIACSLITNECILEYD 255

Query: 245 SDVKLSHAQTLAAAELSKQNFINLICGFLRK 275
           +D  + H + L  A         L+  F+ K
Sbjct: 256 TDKTVCHDEVLQTANDRAHQMQTLVAKFIGK 286


>UniRef50_D1B5G3 Inosine guanosine and xanthosine phosphorylase family n=2
           Tax=Synergistaceae RepID=D1B5G3_THEAS
          Length = 276

 Score =  314 bits (805), Expect = 2e-84,   Method: Composition-based stats.
 Identities = 101/265 (38%), Positives = 154/265 (58%), Gaps = 1/265 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +  I+   P  TP +  +LGSG+G     ++N V++ YE++P +P ST  GHAG L +G
Sbjct: 10  ALGAIRKLVP-VTPDLVMVLGSGVGDFVRVLDNPVSVPYEEIPWWPRSTAPGHAGVLHVG 68

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L  + V  ++GR H+YEG  M  +   +R     G ++   TNA+G +      G  V 
Sbjct: 69  RLGTINVAVLQGRVHYYEGYSMEEVVFPVRVMGEWGAKVFVATNASGGIDRSYSPGQWVL 128

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           ++DHIN M   P+VG N+D +G RF  +  AYD +   L+++ A   G  L  GV+V+  
Sbjct: 129 IEDHINLMGANPLVGPNEDFWGVRFPDMTEAYDRDLMRLMERAASRIGVALGRGVYVAMS 188

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP+FET AEIRM+  +GG +VGMS VPEVI+ARH  L+V+A+S + N A G+S   L+H 
Sbjct: 189 GPSFETPAEIRMLSKLGGTLVGMSTVPEVIAARHMGLRVLALSCVANYAAGISPNPLTHE 248

Query: 253 QTLAAAELSKQNFINLICGFLRKIA 277
           + L     +  +   L+  FL +++
Sbjct: 249 EVLREVSRATGDLCRLLPAFLEEMS 273


>UniRef50_Q7KV94 CG16758, isoform B n=33 Tax=cellular organisms RepID=Q7KV94_DROME
          Length = 353

 Score =  314 bits (805), Expect = 2e-84,   Method: Composition-based stats.
 Identities = 112/272 (41%), Positives = 160/272 (58%), Gaps = 10/272 (3%)

Query: 14  IDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH 73
            D I T      P++  I GSGLG+LAD I++     YEK+P FPVSTV GHAG LV+G 
Sbjct: 78  ADFI-TKGSGMRPKIGIICGSGLGSLADMIQDPKIFEYEKIPNFPVSTVEGHAGRLVVGT 136

Query: 74  LQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVAL 133
           L+G  V+ M+GR HFYEG  +   +  +R  KL G E LF TNAAG + P    G ++ +
Sbjct: 137 LEGATVMAMQGRFHFYEGYPLAKCSMPVRVMKLCGVEYLFATNAAGGINPRFAVGDIMLM 196

Query: 134 KDHINTM---PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVF 188
            DH+N +     +P+ G ND RFG RF +L N+Y+ +      ++AK  G    +  GV+
Sbjct: 197 HDHVNMLGFAGNSPLQGPNDPRFGPRFPALVNSYNKDLINKAIEIAKAMGIESNIHVGVY 256

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL---- 244
               GPN+ET AE++ ++++G D VGMS V EVI+ARHCD+KV A S ITN         
Sbjct: 257 SCLGGPNYETIAELKALRMMGVDAVGMSTVHEVITARHCDMKVFAFSLITNKCATEYSDK 316

Query: 245 SDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
            D + +H + +A A+  ++    L+   +R+I
Sbjct: 317 KDDEANHDEVMAVAKNRQKACCELVSRLIREI 348


>UniRef50_Q3B5L6 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=48 Tax=Bacteria RepID=Q3B5L6_PELLD
          Length = 302

 Score =  313 bits (803), Expect = 4e-84,   Method: Composition-based stats.
 Identities = 98/264 (37%), Positives = 143/264 (54%), Gaps = 1/264 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +  I+    D  P V  +LG+GLGALA +I+   A+ Y  +P FP+STV  H G+L+ G
Sbjct: 40  AVSFIRKKTQDEYP-VGIVLGTGLGALAKEIDVEFALDYADIPNFPISTVETHHGKLIFG 98

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L G  VV M+GR HFYEG  M  +   IR  K LG + L  TNA G L P    G ++ 
Sbjct: 99  TLAGRKVVAMQGRFHFYEGYSMQQIVFPIRVMKHLGVKTLGITNACGGLNPGFQKGDIML 158

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN +PG P++G ND   G RF  +   Y      + ++VA E    +  GV+++  
Sbjct: 159 IDDHINMLPGNPLIGHNDPETGSRFPDMCEPYSKRLLKIAEEVALEHKIKVQRGVYIALS 218

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP  ET AE RM++ +G DVVGMS VPEVI+A H   +V  +S IT+     +   +S  
Sbjct: 219 GPCLETRAEYRMLRTLGADVVGMSTVPEVIAAVHQGTEVFGMSIITDECFPDNLHPVSIE 278

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           + +  +  ++     +    + K+
Sbjct: 279 EIIEVSNHAEPKMTTIFKNVVAKL 302


>UniRef50_C3J8Q8 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=2 Tax=Bacteria RepID=C3J8Q8_9PORP
          Length = 274

 Score =  313 bits (802), Expect = 5e-84,   Method: Composition-based stats.
 Identities = 104/268 (38%), Positives = 150/268 (55%), Gaps = 3/268 (1%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
               D +    P F  ++  ILGSGLG L ++IE+   I Y ++P F  ST  GH G  +
Sbjct: 7   HEAADFLLKRLP-FKAKIGIILGSGLGELGNKIEDPTIIPYSEIPNFAHSTAIGHKGNFI 65

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
            G L GVPVV M+GR H+YEG  M  +T  +R  KL+G E LF +NAAG +      G L
Sbjct: 66  CGKLGGVPVVAMQGRFHYYEGYPMERVTFPVRVMKLIGVETLFVSNAAGGINNTYHVGDL 125

Query: 131 VALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVS 190
           + ++DHIN +P  P++G N   FG RF  +  AYD +  A  +++AKEE   + +GV+V 
Sbjct: 126 MIIRDHINNLP-NPLIGPNMGEFGVRFPDMTRAYDRDLIARAERIAKEENIEVRKGVYVG 184

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
             GP++ET AE    Q +GGD +GMS VPEV+ ARH  ++V  +S ITN          +
Sbjct: 185 LTGPSYETPAEYLFYQRVGGDAIGMSTVPEVLVARHAGIRVFGMSVITNEGWHFEGDYTN 244

Query: 251 HA-QTLAAAELSKQNFINLICGFLRKIA 277
            A + + AA  + +    +    + +IA
Sbjct: 245 DAQEVIDAANAASERMGRIFQRLISEIA 272


>UniRef50_C4QLI3 Purine nucleoside phosphorylase n=2 Tax=Schistosoma mansoni
           RepID=C4QLI3_SCHMA
          Length = 414

 Score =  313 bits (802), Expect = 5e-84,   Method: Composition-based stats.
 Identities = 108/265 (40%), Positives = 152/265 (57%), Gaps = 7/265 (2%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
                  P +  I GSGLG LAD +++ + I Y K+P FP ++V GH+G L+ G L G  
Sbjct: 147 QKLTSIVPEIGIICGSGLGKLADGVKDKITIPYTKIPNFPQTSVVGHSGNLIFGTLSGRK 206

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           VV M+GR H YEG     +   IR  KLLG ++L  +NAAG L   +  G  V LKDHI 
Sbjct: 207 VVVMQGRFHMYEGYSNDTVALPIRVMKLLGVKILMVSNAAGGLNRSLKLGDFVILKDHIY 266

Query: 139 TMP---GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPG 193
                    +VG N + FG RF +L+NAYD + R L  +VA+E GF   + +GV+V   G
Sbjct: 267 LPGLGLNNILVGPNQEEFGTRFPALSNAYDRDLRKLAVQVAEENGFGNLVHQGVYVMNGG 326

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA--EGLSDVKLSH 251
           P +ET AE  M+  +G DVVGMS +PEV+ ARHC ++V AVS +TN++  +  SD+K +H
Sbjct: 327 PCYETPAECTMLLNMGCDVVGMSTIPEVVIARHCGIQVFAVSLVTNISVLDVESDLKPNH 386

Query: 252 AQTLAAAELSKQNFINLICGFLRKI 276
            + LA      +   +     + K+
Sbjct: 387 EEVLATGAQRAELMQSWFEKIIEKL 411



 Score =  145 bits (367), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 48/121 (39%), Positives = 66/121 (54%), Gaps = 5/121 (4%)

Query: 23  DFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM 82
            F P +  I GSGLG LAD +++ + I Y K+P FP ++V GH+G L+ G L G  VV M
Sbjct: 16  RFKPEIGIICGSGLGKLADGVKDKITIPYTKIPNFPQTSVVGHSGNLIFGTLSGRKVVVM 75

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
           +GR H YEG     +   IR  KLLG ++L  +NAAG L   +         D+ N    
Sbjct: 76  QGRFHMYEGYSNDTVALPIRVMKLLGVKILMVSNAAGGLNRSLK-----LDADYFNRRHE 130

Query: 143 T 143
           +
Sbjct: 131 S 131


>UniRef50_B6YR86 Purine-nucleoside phosphorylase n=1 Tax=Candidatus Azobacteroides
           pseudotrichonymphae genomovar. CFP2 RepID=B6YR86_AZOPC
          Length = 270

 Score =  312 bits (801), Expect = 7e-84,   Method: Composition-based stats.
 Identities = 98/264 (37%), Positives = 145/264 (54%), Gaps = 1/264 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +  ++      T ++  ILG+GLG LA+ I N   I YEK+P FP+STV GH G+L++G
Sbjct: 8   TVSWLRPKVSAET-KIGIILGTGLGELANSITNKTEIPYEKIPHFPISTVEGHNGKLLIG 66

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L    V  M+GR H+YEG  M+ +T  +R  + L    L  +NAAG +      G ++ 
Sbjct: 67  QLGEKSVAVMQGRFHYYEGYDMSHITYPVRVMQFLEFNYLIISNAAGGINATFQIGDIML 126

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           ++DHIN  P  P+ G N   FG RF  ++  YD E R+L   V K+    L  G +V   
Sbjct: 127 IEDHINLFPKNPLRGRNFPEFGVRFPDMSQVYDKELRSLAISVTKKNNIKLQFGTYVGVQ 186

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP FET AE    +IIGGD +GMS +PEVI ARH  L+V+A S IT++      ++++H 
Sbjct: 187 GPTFETPAEYNYFRIIGGDAIGMSTIPEVIVARHGGLRVLAFSIITDLGILGKIIEVNHK 246

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
               A   ++     +I   ++ +
Sbjct: 247 DVRKAGNSAQPQMAFIIKEIIKYL 270


>UniRef50_C8V0B3 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           (AFU_orthologue; AFUA_6G05320) n=17 Tax=Leotiomyceta
           RepID=C8V0B3_EMENI
          Length = 315

 Score =  312 bits (800), Expect = 8e-84,   Method: Composition-based stats.
 Identities = 115/299 (38%), Positives = 159/299 (53%), Gaps = 35/299 (11%)

Query: 13  CIDIIKTYKPD--FTPRVAFILGSGLGALADQIEN--AVAISYEKLPGFPVSTVHGHAGE 68
             D IK   P+    PRVA + GSGLG LA+ I+N   V I Y  +P FP  TV GHAG+
Sbjct: 16  AFDFIKKLLPEPLKAPRVAIVCGSGLGGLANTIDNDLRVEIDYSDIPHFPHLTVAGHAGK 75

Query: 69  LVLGHLQG-VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGA 127
           LV G +   VPVV M GR H+YEG  +  +T  IR FKLLG + +  TNAAG L P+   
Sbjct: 76  LVFGLIDKKVPVVLMVGRAHYYEGHSIDQVTFPIRVFKLLGIDTVVLTNAAGGLNPDYAV 135

Query: 128 GSLVALKDHI---NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE-----E 179
           G +V L DHI         P+ G N + FG RF  L++AYD + R  + +  ++      
Sbjct: 136 GDIVLLNDHIFLAGLAGIHPLRGPNCEEFGPRFPPLSDAYDLDLRRQVHEAWRKYLDPCS 195

Query: 180 GFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
              L EGV+    GP++ET AE R+++ +G D+VGMS VPE++ ARHC L+++A S +TN
Sbjct: 196 KRRLHEGVYAFVCGPSYETRAECRLLRQLGADLVGMSTVPEIVVARHCGLRIIAFSLVTN 255

Query: 240 MA----------------------EGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
            A                        L + K +H + L A   + Q+   L+   + KI
Sbjct: 256 NAVLSPVPRGDDHLIQGRDVKELDAILQEGKANHEEVLEAGREAAQDMQKLVVHVISKI 314


>UniRef50_Q0TU47 Purine nucleoside phosphorylase n=7 Tax=Clostridium perfringens
           RepID=Q0TU47_CLOP1
          Length = 272

 Score =  312 bits (799), Expect = 1e-83,   Method: Composition-based stats.
 Identities = 105/263 (39%), Positives = 156/263 (59%), Gaps = 1/263 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
             + IK+ K  ++P++  +LG+GLG LA++IE A    Y  +P FPV T+ GH G L++G
Sbjct: 10  AYEYIKS-KSKYSPKIGLVLGTGLGDLANEIEEAEYYRYMDIPNFPVPTIAGHEGTLIIG 68

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L G  V+ MKGR H+YEG  M  +T  IR  KLLG E L  TN +G  +  + AG LV 
Sbjct: 69  KLHGREVIAMKGRCHYYEGHSMQRITLPIRVMKLLGVETLVVTNCSGQAKESIEAGDLVV 128

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           +++HIN     P+ G N   FGERF  LA  YD + R  ++ +AK+    L EGV+  + 
Sbjct: 129 IRNHINFTGDNPLRGENLLEFGERFPDLAYPYDKDLREEVKNIAKDLDINLKEGVYAMFS 188

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP++ETA E  M   +G DVVGMS VPEVI A HC +KV+  S +  +A   S+ +++H 
Sbjct: 189 GPSYETAVETLMAASLGADVVGMSTVPEVIVANHCGIKVLGFSGVPCLAAAYSEAEITHE 248

Query: 253 QTLAAAELSKQNFINLICGFLRK 275
           + +   +   +   +++  FL++
Sbjct: 249 EAMVNFQSITEKCTSIVKEFLKR 271


>UniRef50_B0VG85 Purine nucleoside phosphorylase 1 (Purine nucleoside phosphorylase
           I) (PNP I) (PU-NPase I) (Inosine phosphorylase) n=1
           Tax=Candidatus Cloacamonas acidaminovorans
           RepID=B0VG85_9BACT
          Length = 277

 Score =  311 bits (797), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 104/265 (39%), Positives = 153/265 (57%), Gaps = 1/265 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
               +KT  P   P++A ILG+GL  +A+      +I Y ++PGF  ST   H G L+L 
Sbjct: 7   TSAWLKTKLPK-QPQIAVILGTGLSNMAEVFPLLYSIPYNQIPGFVQSTAPTHKGNLLLC 65

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            ++G+PV+ ++GR H+YEG  M  +   +R    LG ++L  TNA+GSLR E+  G++V 
Sbjct: 66  EVEGIPVIFLQGRFHYYEGYSMQEVVFPVRVLSALGIKVLIVTNASGSLRKELEPGTIVQ 125

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           L+DHIN M   P++G+NDD  GERF S+   YD E   L  KVA + G    +GV+++  
Sbjct: 126 LQDHINFMGTNPLIGMNDDDLGERFPSMNKVYDPELCLLADKVAFDLGIKTAKGVYIAVT 185

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP+ ET AE       G D+VGMS VPEVI+ARH  LKV+A S +TN +    ++  S  
Sbjct: 186 GPSLETKAECSAFASWGADLVGMSTVPEVITARHSGLKVLAYSIVTNYSNLFHNLAHSQE 245

Query: 253 QTLAAAELSKQNFINLICGFLRKIA 277
           +    A +S +    LI   + ++ 
Sbjct: 246 EIQRIANISGKQLQKLIAELILRLT 270


>UniRef50_D0MFN5 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Rhodothermus marinus DSM 4252 RepID=D0MFN5_RHOM4
          Length = 279

 Score =  311 bits (797), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 109/263 (41%), Positives = 147/263 (55%), Gaps = 3/263 (1%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +D ++    +  P VA ILGSGLGALA+ +  AV +   ++PG+P  TV GHAG LV G
Sbjct: 10  ALDWLRPKLRE-APEVALILGSGLGALAEAVSEAVEVPVREIPGYPAPTVSGHAGRLVFG 68

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L+G  VV ++GR H YEG     +T  +R    LG + L  TNAAG L P    G+L+ 
Sbjct: 69  RLEGCRVVVLQGRLHCYEGYPPQTVTLPVRLVHALGAQRLIVTNAAGGLNPHFRPGTLMF 128

Query: 133 LKDHINTMPGTPMVGLNDDR--FGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVS 190
           + DHIN     P+VG   DR         ++ AYD ++ A  + VA   G P   GV++ 
Sbjct: 129 IVDHINAAFRNPLVGQLADRRPLMRGAPDMSRAYDLDWLAEAETVALRLGIPTQRGVYLW 188

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
             GP++ET AEIRM + +G D VGMS VPEV+ AR   +KV+ +S ITNMA GL    L+
Sbjct: 189 TLGPSYETKAEIRMYRRMGADAVGMSTVPEVLQARQLGMKVLGISTITNMAAGLHAGPLT 248

Query: 251 HAQTLAAAELSKQNFINLICGFL 273
           H + L      +     LI G L
Sbjct: 249 HEEVLQVGLQVRDRLERLIRGIL 271


>UniRef50_C3ZRV1 Putative uncharacterized protein (Fragment) n=1 Tax=Branchiostoma
           floridae RepID=C3ZRV1_BRAFL
          Length = 286

 Score =  311 bits (796), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 103/263 (39%), Positives = 148/263 (56%), Gaps = 6/263 (2%)

Query: 20  YKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPV 79
               + P+VA I GSGLG LAD ++    I Y  +P FP STV GH G LV GHL G  V
Sbjct: 14  KTTKYRPKVAVICGSGLGGLADVVQQQDVIDYRDIPNFPQSTVQGHRGRLVFGHLAGKSV 73

Query: 80  VCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN- 138
           +CM+GR H Y+G  +  +   +R FK++G E LF TNAAG L      G ++ +KDHI+ 
Sbjct: 74  ICMQGRFHQYQGYPLWKVAMPVRVFKMIGVETLFVTNAAGGLNRNYNIGDIMIVKDHISM 133

Query: 139 --TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF--PLTEGVFVSYPGP 194
                  P+ G  D+RFG+    +   YD   R L ++VA + G    + EGV V   GP
Sbjct: 134 PGMTTDNPLKGFYDERFGKPSSPVTELYDRGLRELARRVAGDLGLGEAVREGVLVQVGGP 193

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VKLSHAQ 253
           +F+T +   M++ +G D VGMS  PEV  ARHC ++V+ +S +T+MA   SD    +H +
Sbjct: 194 SFDTVSVFNMLRRLGADCVGMSSAPEVTVARHCGIRVLGLSLVTDMAPMESDLPPTNHQE 253

Query: 254 TLAAAELSKQNFINLICGFLRKI 276
            L  A+    +  NL+C  + ++
Sbjct: 254 ILQTAKTRAVDVQNLVCEMISQL 276


>UniRef50_A7HJP7 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Fervidobacterium nodosum Rt17-B1
           RepID=A7HJP7_FERNB
          Length = 267

 Score =  310 bits (795), Expect = 3e-83,   Method: Composition-based stats.
 Identities = 101/264 (38%), Positives = 150/264 (56%), Gaps = 5/264 (1%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
             + I++ K    P++A ILGSGLG L +++E    ++Y+ +P FP ST  GH G+LV G
Sbjct: 8   ACEFIES-KIKTKPKIALILGSGLGFLTEKVEFKQELNYKDIPNFPYSTAPGHEGKLVFG 66

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L G  VV + GR H YEG   + +   I T K+LG E +  TNAAG++      G +V 
Sbjct: 67  ELFGKEVVVLSGRFHIYEGWNPSDIKIVIHTLKMLGIEKILITNAAGAVNTTYKPGDIVL 126

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           +KD IN     P+ G ND+  G RF  +   +D ++   L+++  E      EGV++S  
Sbjct: 127 VKDVINFTFRNPLRGPNDNDLGPRFPDMLGVFDKDWMGKLKQIYPEM----KEGVYISLT 182

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP +ET AEIR ++ +G D+VGMS VPE+I   H  +K + +S  TNMA G+ D  LSH 
Sbjct: 183 GPTYETPAEIRAVRKMGADLVGMSTVPELIVCAHVGIKALVLSCATNMAAGILDQPLSHE 242

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           + +  A L K+ F  ++   L  +
Sbjct: 243 EVVEVANLVKEKFTEIVKKALEVL 266


>UniRef50_D1Y3S3 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y3S3_9BACT
          Length = 279

 Score =  310 bits (795), Expect = 3e-83,   Method: Composition-based stats.
 Identities = 105/264 (39%), Positives = 145/264 (54%), Gaps = 1/264 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            ++ I+       PR A ILGSGLG LA+ +E+ V I Y ++P +  ST  GHAG LV G
Sbjct: 13  ALEAIEARVSGV-PRAALILGSGLGMLAEAVEDPVVIPYAEIPHWKTSTAPGHAGRLVCG 71

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L GVPVV M+GR H YEG      T  IR F   G + L  TNA+G +  E   G +  
Sbjct: 72  TLSGVPVVVMQGRLHCYEGYTPQETTFPIRVFGQWGVKTLLVTNASGGINYEYANGDVAL 131

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN     P+ G N+  +G RF  ++  Y     ALL++ A+  G     GV++   
Sbjct: 132 ITDHINLTGMNPLRGANNPEWGARFPDMSEPYSRRLVALLEESAQSLGLLTRRGVYIGLA 191

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP++ET AEIRM + +G D+VGMS V EVI A H  ++V  VS + N+A G+  VKLS  
Sbjct: 192 GPSYETPAEIRMARAMGADLVGMSTVHEVIVANHMGMEVCGVSCVANLAAGMRPVKLSEE 251

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           + L+    +      L+  FL  +
Sbjct: 252 EVLSEMGRAAARISALVGKFLELL 275


>UniRef50_A0NS72 Purine nucleoside phosphorylase n=7 Tax=Alphaproteobacteria
           RepID=A0NS72_9RHOB
          Length = 269

 Score =  310 bits (794), Expect = 4e-83,   Method: Composition-based stats.
 Identities = 125/264 (47%), Positives = 172/264 (65%), Gaps = 4/264 (1%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
           C DI++  + + + ++  ILGSGLGALA+++E+AV I Y  L  FPVSTV  H+ ELV G
Sbjct: 8   CADIVRAAR-EGSYKIGMILGSGLGALAEEVEDAVRIPYSHLTEFPVSTVTSHSSELVAG 66

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L GVPVV + GR H+YEG   T+M   + T K LGCE+L  TNAAGSLR EV  GS + 
Sbjct: 67  TLSGVPVVILSGRAHYYEGGDPTVMRTPVETLKELGCEILLATNAAGSLRQEVAPGSPML 126

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN     P++G  D++   RF  ++ AYDA+ RA ++KVA+E G P+ EGV++ + 
Sbjct: 127 ISDHINWSGMNPLIGEEDEK---RFLDMSTAYDADLRAAMKKVAEETGDPVAEGVYMWFS 183

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP+FET AEIRM + +G D VGMS VPEVI AR   ++V A+S ITN   G+    LSH 
Sbjct: 184 GPSFETPAEIRMAKTLGADAVGMSTVPEVIMARFLGMRVAAMSIITNYGAGMQTHALSHD 243

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           +T + A    +    L+  F+++I
Sbjct: 244 ETKSVALQGMERMKELVRAFVKEI 267


>UniRef50_Q9BMI9 Purine-nucleoside phosphorylase n=1 Tax=Schistosoma mansoni
           RepID=Q9BMI9_SCHMA
          Length = 287

 Score =  310 bits (794), Expect = 4e-83,   Method: Composition-based stats.
 Identities = 108/265 (40%), Positives = 152/265 (57%), Gaps = 7/265 (2%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
                  P +  I GSGLG LAD +++ + I Y K+P FP ++V GH+G L+ G L G  
Sbjct: 20  QKLTSIVPEIGIICGSGLGKLADGVKDKITIPYTKIPNFPQTSVVGHSGNLIFGTLSGRK 79

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           VV M+GR H YEG     +   IR  KLLG ++L  +NAAG L   +  G  V LKDHI 
Sbjct: 80  VVVMQGRFHMYEGYSNDTVALPIRVMKLLGVKILMVSNAAGGLNRSLKLGDFVILKDHIY 139

Query: 139 TMP---GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPG 193
                    +VG N + FG RF +L+NAYD + R L  +VA+E GF   + +GV+V   G
Sbjct: 140 LPGLGLNNILVGPNQEAFGTRFPALSNAYDRDLRKLAVQVAEENGFGNLVHQGVYVMNGG 199

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA--EGLSDVKLSH 251
           P +ET AE  M+  +G DVVGMS +PEV+ ARHC ++V AVS +TN++  +  SD+K +H
Sbjct: 200 PCYETPAECTMLLNMGCDVVGMSTIPEVVIARHCGIQVFAVSLVTNISVLDVESDLKPNH 259

Query: 252 AQTLAAAELSKQNFINLICGFLRKI 276
            + LA      +   +     + K+
Sbjct: 260 EEVLATGAQRAELMQSWFEKIIEKL 284


>UniRef50_B9WDS7 Purine nucleoside phosphorylase, putative n=14 Tax=cellular
           organisms RepID=B9WDS7_CANDC
          Length = 307

 Score =  309 bits (793), Expect = 5e-83,   Method: Composition-based stats.
 Identities = 119/295 (40%), Positives = 162/295 (54%), Gaps = 23/295 (7%)

Query: 5   QFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQI--ENAVAISYEKLPGFPVSTV 62
           Q +H      + I  ++    PRV  I GSGLG +AD +  E  + I Y K+PGF VSTV
Sbjct: 13  QLNHASDTIKNKIDQFQELAQPRVMIICGSGLGGIADVLQAEPKLEIPYSKIPGFKVSTV 72

Query: 63  HGHAGELVLGHLQG--VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
            GHAG+LV G +    VPV+CM GR HFYEG      T  +R  KLLG   +  TNAAG 
Sbjct: 73  PGHAGKLVFGLIGKSKVPVMCMVGRLHFYEGYSFQETTFPVRVAKLLGISSVVVTNAAGG 132

Query: 121 LRPEVGAGSLVALKDHINT---MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAK 177
           + P+   G L+ ++DHIN        P+ G N   FG RF  L++AYD E R L    A+
Sbjct: 133 VNPKFKPGDLMVIEDHINFPGLAGYHPLRGPNLSEFGPRFQPLSDAYDYELRKLFITTAR 192

Query: 178 -EEGF--PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAV 234
            + G    + EG +    GP FE+ AE+RM++ +GGD VGMS VPEVI ARH  L+V+A+
Sbjct: 193 DKLGITRSIYEGTYFFAAGPTFESRAEVRMIKTMGGDAVGMSTVPEVIVARHSGLRVLAL 252

Query: 235 SAITNMAEG-------------LSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           S ITN   G             L +   SHA+ L AA+ + ++   +I   + ++
Sbjct: 253 SLITNAGVGDKPPSAFDENPPALDEGMASHAEVLEAADEASKDVQKIIEEVINQL 307


>UniRef50_A7VBG8 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A7VBG8_9CLOT
          Length = 306

 Score =  309 bits (791), Expect = 9e-83,   Method: Composition-based stats.
 Identities = 98/259 (37%), Positives = 146/259 (56%), Gaps = 2/259 (0%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
           T K    P +  +LGSGLG  A  +++ V + Y+++PGFPVSTV GH G  + G+  G P
Sbjct: 46  TDKIKMKPEIGIVLGSGLGD-AFTMDDPVYVYYKEIPGFPVSTVAGHKGRFIFGYSCGKP 104

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           +V M+GR H+YEG  M  +   IR   LLG   L  TNAAG +  E+  G ++ + D I+
Sbjct: 105 IVVMQGRVHYYEGYSMQDVVKPIRLMGLLGIRWLILTNAAGGISEELAPGDIMIISDQIS 164

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFET 198
           +   +P++G N D FG RF  +++ YD E   + +KV ++ G  + EG ++   GP +ET
Sbjct: 165 SFVPSPLIGRNIDEFGVRFPDMSHIYDKEKIQISRKVFEQIGLHVVEGTYIQATGPQYET 224

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
            AEIRM Q++G D VGMS   E I+A H  ++V   SAI+N A GL   +L H   L  +
Sbjct: 225 PAEIRMFQLLGADAVGMSTACEAIAACHMGIRVSGFSAISNKAAGLG-AELKHEDILDRS 283

Query: 259 ELSKQNFINLICGFLRKIA 277
           +        L+   +   +
Sbjct: 284 KEMSDKMSRLLTELIESYS 302


>UniRef50_D2MQ16 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Bulleidia extructa W1219 RepID=D2MQ16_9FIRM
          Length = 273

 Score =  308 bits (790), Expect = 1e-82,   Method: Composition-based stats.
 Identities = 102/264 (38%), Positives = 152/264 (57%), Gaps = 1/264 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +D I+T K D  P +  ILGSGLG L  Q+EN + I+Y+++PGF  +T   H GEL+ G
Sbjct: 11  ALDFIRT-KTDMVPEIGLILGSGLGTLVTQLENTITIAYQEIPGFLQTTNPSHKGELIFG 69

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L G  VVCM GR H YEG   + +   +R  KLLG ++L  TNAAG++      G ++ 
Sbjct: 70  FLNGKKVVCMSGRFHSYEGFSFSELVIPVRLLKLLGIQILMTTNAAGAVNESYRPGDVMI 129

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           ++DH+     +PM G N++ FG RF+ ++  Y  E R   ++VA++      EG +    
Sbjct: 130 IRDHLFFGIESPMRGFNEEDFGSRFYDVSTLYTPELREKAKEVARDFPLTFHEGNYFFMQ 189

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP+FET AEIR ++I+GGD VGMS V E ++A HC LKV++ S  TNMA G+ +  LS  
Sbjct: 190 GPHFETPAEIRAIRILGGDTVGMSTVTETLTAGHCGLKVLSFSVCTNMAAGILEQPLSDE 249

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           +          +    +   + ++
Sbjct: 250 EVNEVGRNISSHLAAYMYELVGQL 273


>UniRef50_A8PXS8 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           family protein n=4 Tax=root RepID=A8PXS8_BRUMA
          Length = 295

 Score =  308 bits (789), Expect = 1e-82,   Method: Composition-based stats.
 Identities = 104/274 (37%), Positives = 153/274 (55%), Gaps = 8/274 (2%)

Query: 10  PLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGEL 69
                 I+K  +    P++  I GSGLG++AD IE A  +SY K+PGFP+S V GH   L
Sbjct: 23  SEIAKSILKQIQLKEVPKIGIICGSGLGSIADFIEQAEILSYTKIPGFPISHVIGHKSNL 82

Query: 70  VLGHLQGVPVVCMKGRGHFYE-GRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAG 128
           V G++    V+CM+GR H YE G  + +    +R   LLG E L  +NAAG L      G
Sbjct: 83  VFGYINEKYVICMQGRFHPYEYGMDLALCAMPVRILHLLGVETLIVSNAAGGLNSNFKVG 142

Query: 129 SLVALKDHINTMPG----TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT 184
            L+ +KDHI   PG    +P VGL+D RFGERF SL  AYD + R L   VA+ +   + 
Sbjct: 143 DLMIIKDHI-FFPGLAGFSPFVGLHDQRFGERFVSLHEAYDPKLRKLAIDVARRQKIRIH 201

Query: 185 EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL 244
           EGV+    GP FE+ AE+RM++++G D +GMS   EV+ A    ++V   S ITN+A   
Sbjct: 202 EGVYAMNGGPQFESPAELRMLKMLGTDAIGMSTCHEVVVACQMGMRVFGCSLITNIANLD 261

Query: 245 SDVK--LSHAQTLAAAELSKQNFINLICGFLRKI 276
            +    ++H + L   E +++   + +   ++ +
Sbjct: 262 HENAVMVTHEEVLKTGEEAQERTCSFVSEIVKNL 295


>UniRef50_Q5YBA4 Purine nucleoside phosphorylase n=2 Tax=Singapore grouper
           iridovirus RepID=Q5YBA4_9VIRU
          Length = 285

 Score =  306 bits (785), Expect = 4e-82,   Method: Composition-based stats.
 Identities = 99/265 (37%), Positives = 143/265 (53%), Gaps = 7/265 (2%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
             +    P +  + GSGLG + D +E ++ ++Y  +P FPV +V GHAG L+ G + GV 
Sbjct: 15  NKQLQIRPVLGIVCGSGLGKIGDSLETSITVAYSDIPNFPVGSVKGHAGSLIFGSVNGVS 74

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
            VCMKGR H YEG      T  +R FK LG +++  TNAAG L P    G  + ++DHIN
Sbjct: 75  CVCMKGRFHLYEGHTAARATFPMRVFKALGVKIVVLTNAAGGLNPSYRPGDFMVVRDHIN 134

Query: 139 ---TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL--TEGVFVSYPG 193
                   P+ G NDD  GERF S+ + YD   R      A+E G      EGV+    G
Sbjct: 135 LPGLAGANPLTGPNDDTEGERFPSMTSVYDKTLRKYAISAARELGMSYATHEGVYCCVNG 194

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKL--SH 251
           P+FET AE ++++++G D VGMS  PE I A+H  ++ +AVS I+N+     +     +H
Sbjct: 195 PSFETPAECKILRLMGSDAVGMSTAPETIVAKHGGMRCLAVSLISNVIASNCETPAEPTH 254

Query: 252 AQTLAAAELSKQNFINLICGFLRKI 276
            + L A E +      L+   + KI
Sbjct: 255 EEVLRAGEEASARMTALVKLVIEKI 279


>UniRef50_C7LVA5 Inosine guanosine and xanthosine phosphorylase family n=2
           Tax=Desulfovibrionales RepID=C7LVA5_DESBD
          Length = 278

 Score =  305 bits (782), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 101/266 (37%), Positives = 136/266 (51%), Gaps = 1/266 (0%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
           L   + IK   P   P+   +LGSGLG          +I Y  +PGFPVSTV GHAG L+
Sbjct: 9   LTATEWIKNNCPS-APKTGLVLGSGLGKWIKPAWIQKSIPYSDIPGFPVSTVEGHAGALL 67

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
           +  ++G PV    GR H YEG     +T  I    LLG   L  TNAAG+L P    G L
Sbjct: 68  VAEIKGTPVFIFSGRFHLYEGYRPQEVTLPIVCLALLGAGNLILTNAAGALNPLFATGGL 127

Query: 131 VALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVS 190
           + L DHIN     P+ G N D +G RF  ++  Y    R    +     G  L +GV+V+
Sbjct: 128 MLLTDHINMTGHNPLTGPNVDAWGPRFPDMSQVYCPTLREQAMQAGLACGQRLEQGVYVA 187

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
             GP+ ET AE RM +I+G D +GMS  PE I+A H  LKV+ +S +TN        + S
Sbjct: 188 VAGPSLETPAETRMYRIMGADAIGMSTAPEAITAHHMGLKVLGISCLTNKNLPDCMAETS 247

Query: 251 HAQTLAAAELSKQNFINLICGFLRKI 276
           HA+ L+ A  S     +L+   +  +
Sbjct: 248 HAEILSQANASADALGSLLSALIPNL 273


>UniRef50_A5USV0 Inosine guanosine and xanthosine phosphorylase family n=19
           Tax=Bacteria RepID=A5USV0_ROSS1
          Length = 297

 Score =  305 bits (781), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 114/263 (43%), Positives = 151/263 (57%), Gaps = 4/263 (1%)

Query: 17  IKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQG 76
           I   +    PR+A ILGSGLG LAD +  +V I Y ++PGF    V GH GELV+G L G
Sbjct: 23  IIAARSPIEPRIALILGSGLGDLADAVTESVTIPYTEIPGFVQPAVVGHRGELVIGLLAG 82

Query: 77  VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDH 136
            PV  M+GR HFYEG  M  +T  +R    LGC  L  TNAAG L  +   G L+ + DH
Sbjct: 83  QPVAVMRGRFHFYEGHSMQQVTFPVRVLHALGCTALLATNAAGGLHADWRVGDLMLITDH 142

Query: 137 I---NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPG 193
           I         P+ G NDDR G RF  +  AYD   +A+ + VA E G  L EGV++   G
Sbjct: 143 IFLPGLAGHHPLRGPNDDRLGPRFPPMVGAYDPTLQAVARAVAAELGIALREGVYMMLSG 202

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQ 253
           P FE++AE+RM + +G D VGMS  PEV+ ARH  ++ + +S ITN+A        SH +
Sbjct: 203 PAFESSAELRMCRALGADAVGMSTAPEVVVARHMGMRCLGLSLITNLALPDGP-PASHQE 261

Query: 254 TLAAAELSKQNFINLICGFLRKI 276
            L A + ++  F  LICG L ++
Sbjct: 262 VLDAGDAARPAFTALICGILARM 284


>UniRef50_A4CJ72 Purine nucleoside phosphorylase n=15 Tax=Bacteroidetes
           RepID=A4CJ72_9FLAO
          Length = 271

 Score =  304 bits (780), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 95/252 (37%), Positives = 145/252 (57%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
            P +  +LGSGLG +AD++E++    Y  +P FP++TV  H+G+L  G + G  VV M+G
Sbjct: 20  NPEIGIVLGSGLGRMADELEDSRVAHYHNIPNFPLATVEFHSGKLFCGTIHGKKVVVMQG 79

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H YEG     +T  IR  + LG   L  +NAAG++  +   G L+ + DHIN   G+P
Sbjct: 80  RFHLYEGYDFFDITYPIRVMERLGIRKLLISNAAGAVNLDFQKGDLMLITDHINLQGGSP 139

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           +   N   FGERF  ++  YD E +  ++++AK     L EGV+ +  GP  ET AE RM
Sbjct: 140 LAFKNVADFGERFVDMSCPYDREMQGRIREIAKGTDCVLREGVYAAVFGPQLETRAEYRM 199

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           +  +G D VGMS VPEVI A H  L V A+S IT++ +  +   ++  + LA A  ++  
Sbjct: 200 LGRLGADAVGMSTVPEVIVANHLKLPVAAISVITDLGDPDNLEPVNVTEILAVAARAEPG 259

Query: 265 FINLICGFLRKI 276
            + ++   +R+I
Sbjct: 260 LVRIMKELIREI 271


>UniRef50_D2QX64 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2QX64_9PLAN
          Length = 303

 Score =  303 bits (776), Expect = 5e-81,   Method: Composition-based stats.
 Identities = 105/262 (40%), Positives = 147/262 (56%), Gaps = 1/262 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
               IK+     TP    ILG+GLG+L DQIE   AI YE +P FP ST   H G LV G
Sbjct: 38  AAAFIKSQWSS-TPHAGIILGTGLGSLVDQIEVEAAIDYENIPHFPKSTAISHRGRLVCG 96

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L  +PV+ M+GR H YEG  +  +T  +R  K +G  LL  +NA G + P+   G ++ 
Sbjct: 97  KLGKLPVMAMEGRFHMYEGYPLDQVTLPVRVMKAMGANLLVVSNACGGMNPQYRTGDIML 156

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           ++DHIN M   P++G+NDDR G RF  + + Y+        ++A++E      GVFV+  
Sbjct: 157 IEDHINLMGANPLIGINDDRLGPRFPDMCHPYEPALIDRALEIARKENIVAHRGVFVAVS 216

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GPN ET AE R +++IG DVVGMS VPEVI A H +++VV  S IT+M    +       
Sbjct: 217 GPNLETRAEYRFLRLIGADVVGMSTVPEVIVAVHSNMRVVGFSIITDMCLPDALEPADVQ 276

Query: 253 QTLAAAELSKQNFINLICGFLR 274
           + +A A  ++     L+ G L 
Sbjct: 277 KIIAVANTAQPKLCKLVQGVLA 298


>UniRef50_B9XJR6 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=bacterium Ellin514 RepID=B9XJR6_9BACT
          Length = 274

 Score =  302 bits (774), Expect = 9e-81,   Method: Composition-based stats.
 Identities = 108/269 (40%), Positives = 140/269 (52%), Gaps = 2/269 (0%)

Query: 9   NPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGE 68
           NPL     +        P +A +LGSG      ++   + ISYEKL GFP   V GHAG+
Sbjct: 6   NPLITAQQLG-RLSQLRPTLAIVLGSGFQQAIAEMRIELEISYEKLKGFPPVGVSGHAGK 64

Query: 69  LVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAG 128
           L+LG+L   PV+ + GR H+YEG  M  +T A R     G   L  TNAAG +  +  AG
Sbjct: 65  LILGYLGKTPVLVLSGRAHYYEGHEMEQVTYATRVLAEFGIRDLLLTNAAGGVNRKFKAG 124

Query: 129 SLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVF 188
             + L DHIN M   P+ G    +   RF  +   YD +   LL K  K  G  L +GV+
Sbjct: 125 DFMVLTDHINFMGINPLRGPTIAKL-PRFVDMTCTYDQQLSQLLHKAGKLCGLKLQKGVY 183

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK 248
           ++  GP++ET AEIR    +G D VGMS VPE I AR C + V  VS ITN+A G     
Sbjct: 184 LAVSGPSYETPAEIRAFATLGADAVGMSTVPEAIVARQCGINVAGVSCITNLAAGCGGDT 243

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKIA 277
           LSHA+ L  AE  K     L+  F +  A
Sbjct: 244 LSHAEVLETAERVKNMAARLLNSFAKLYA 272


>UniRef50_C7MNU9 Inosine guanosine and xanthosine phosphorylase family protein n=2
           Tax=Coriobacteriaceae RepID=C7MNU9_CRYCD
          Length = 284

 Score =  302 bits (773), Expect = 1e-80,   Method: Composition-based stats.
 Identities = 105/268 (39%), Positives = 142/268 (52%), Gaps = 6/268 (2%)

Query: 16  IIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQ 75
            ++      +P++  +LGSGL  LAD+I +AV I + ++P     T  GH G  V G L 
Sbjct: 17  FLRQRLHGRSPQIGLVLGSGLNPLADKIADAVHIDFTEVPHMKTVTAAGHVGRFVCGELG 76

Query: 76  GVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKD 135
           G  V+ M+GR H YEG     +   I     LG E +  TNAAG+L      G   A+ D
Sbjct: 77  GQTVLAMQGRLHAYEGYTAQDVAFPIWLMHRLGIETVITTNAAGALNKSFAPGDFCAISD 136

Query: 136 HINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPN 195
           HIN     P+VG++     ER FS+  AYDA  RA    VA E+   L EGV++   GP+
Sbjct: 137 HINFTGRNPIVGIDPSELAERCFSMTAAYDATLRATAHTVASEKSITLHEGVYLGVLGPS 196

Query: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH---- 251
           FET AEIRM +  G D V MSVV EVI+ARH  ++V+ +S ITN A GL +         
Sbjct: 197 FETPAEIRMFRSWGADTVAMSVVEEVIAARHVGMRVLGLSLITNCAAGLGETDTCDANAA 256

Query: 252 --AQTLAAAELSKQNFINLICGFLRKIA 277
                LA A   + +F  L+ G L K++
Sbjct: 257 NGEAVLATASAYQDDFAALVIGILEKLS 284


>UniRef50_C5EQ75 Purine nucleoside phosphorylase I n=1 Tax=Clostridiales bacterium
           1_7_47FAA RepID=C5EQ75_9FIRM
          Length = 270

 Score =  302 bits (773), Expect = 1e-80,   Method: Composition-based stats.
 Identities = 96/264 (36%), Positives = 149/264 (56%), Gaps = 1/264 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +D I++      P +A ILGSGLG  A Q+ENA  I YE +P FP  TV GH+G L +G
Sbjct: 8   TVDYIRSR-TRKVPEIAMILGSGLGDYASQLENADIIPYEDIPNFPKPTVSGHSGRLFVG 66

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            + G  +  M+GR H+YEG     +T  +R  ++LG   L  TNA G++      G L+ 
Sbjct: 67  EIAGKCIAVMQGRNHYYEGYDTQTITYPVRVLRMLGAGSLILTNACGAVSRHFVPGDLMI 126

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           +++H+      P+ G + +  G RF  ++  YD EY  L ++ AK+ G  + +GV+  +P
Sbjct: 127 IENHLAHFCPPPLRGAHLEELGPRFTDMSRPYDPEYMELARRCAKDMGIRIQQGVYGYWP 186

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP +ETAAE+R   ++G DVVGMS V E + A +C ++V+ +S ITNM    S  K SH 
Sbjct: 187 GPTYETAAEVRAYGVLGADVVGMSTVAEDMVAVNCGMRVLGISCITNMTCIHSSGKTSHD 246

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           + +   E   +  + L+   + ++
Sbjct: 247 EVIQVMEQISEKTVKLLNRIVEEM 270


>UniRef50_B7A7P1 Inosine guanosine and xanthosine phosphorylase family n=3
           Tax=Thermaceae RepID=B7A7P1_THEAQ
          Length = 276

 Score =  299 bits (766), Expect = 7e-80,   Method: Composition-based stats.
 Identities = 98/264 (37%), Positives = 149/264 (56%), Gaps = 1/264 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +  I+  K  F P V  +LGSGLG LA+++E    + Y ++P FP+ST  GHAG LVLG
Sbjct: 13  AVAAIRQ-KTGFAPEVGIVLGSGLGPLAEEVEKVAEMPYGEIPHFPLSTAPGHAGRLVLG 71

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L+G  V+  +GR H+YEG     +   +R    LG      T+AAG L P   AG ++ 
Sbjct: 72  TLEGKRVLVYQGRVHYYEGYSAEEVVFPVRVGFFLGARTFLLTSAAGGLNPRFQAGGIML 131

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
             D++N     P+ G ND+R G RF  +  AYD E   L ++VA+++   L EGV+  + 
Sbjct: 132 HLDYLNPSGVNPLRGKNDERLGPRFPVMFGAYDPELVELARRVARKQDLHLFEGVYAWFL 191

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP+F + AE++M++ +G D +GMS VPEVI+ RH   +V+ +S IT+MA    +   +  
Sbjct: 192 GPSFASRAELKMLRELGADAIGMSTVPEVIALRHLGARVLGLSTITDMAVPEREHHATEE 251

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           + L  A  +   F   + G L ++
Sbjct: 252 EVLEVARRTGPVFRRFVRGILAEL 275


>UniRef50_C1AAZ0 Purine nucleoside phosphorylase n=1 Tax=Gemmatimonas aurantiaca
           T-27 RepID=C1AAZ0_GEMAT
          Length = 277

 Score =  297 bits (762), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 110/274 (40%), Positives = 157/274 (57%), Gaps = 3/274 (1%)

Query: 5   QFSHNPLFCIDIIKTYKPDFTPR--VAFILGSGLGALADQIENAVAISYEKLPGFPVSTV 62
             +       D I+       P      +LGSGLG LAD++ +AV I +  +PGFP +TV
Sbjct: 1   MGAGAARVAADYIRQRVGPAAPAPVCGIVLGSGLGGLADRLVDAVRIPFSHVPGFPTATV 60

Query: 63  HGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLR 122
            GHAG+L++G L   PVV + GR H YEG    +    +R    LG  +   +NAAG +R
Sbjct: 61  AGHAGQLLVGTLADRPVVALAGRFHMYEGHEAALAAFPVRVLHALGAPVYIASNAAGGVR 120

Query: 123 PEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP 182
               AG L+ + DH+N M   P++G  +    ERF  +++ YD + RA ++  A+  G P
Sbjct: 121 RTFSAGDLMLIADHMNLMFRNPLIGSTEPGD-ERFPDMSDPYDRDLRARMRAAAQVVGVP 179

Query: 183 LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAE 242
           L EGV+    GP +ET +E+RM++ +G D VGMS VPEVI AR   ++ VAVS ITN A 
Sbjct: 180 LHEGVYCGLLGPTYETPSEVRMLERMGVDAVGMSTVPEVIVARALGMRAVAVSCITNKAA 239

Query: 243 GLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           GLS  KLSHA+ + A +    +F  LI  F+R++
Sbjct: 240 GLSAEKLSHAEVMEAGKAVAGHFEALITEFVRQL 273


>UniRef50_A3ZZ29 Purine nucleoside phosphorylase n=1 Tax=Blastopirellula marina DSM
           3645 RepID=A3ZZ29_9PLAN
          Length = 267

 Score =  296 bits (757), Expect = 9e-79,   Method: Composition-based stats.
 Identities = 97/258 (37%), Positives = 153/258 (59%), Gaps = 1/258 (0%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
             + +  P+   ILG+GLG+L + I+   +I Y+ LP FP +T   HAG L+ G L GV 
Sbjct: 9   RRRWNRRPKAGVILGTGLGSLTEGIDVEASIDYDDLPYFPQTTALSHAGRLIGGKLAGVD 68

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           V+ M+GR H YEG  +  +T  +R  K LG ELL  +NA+G + P   +G ++ ++DHIN
Sbjct: 69  VLVMEGRFHLYEGYSLDQITLPVRVMKALGAELLVVSNASGGMNPYYESGDIMLIEDHIN 128

Query: 139 TMPGTPMVGLNDD-RFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFE 197
            M  +P+ G  D+ +  ERF  +++ YD        ++A+ E   + +GV+V+  GPN+E
Sbjct: 129 LMWRSPLQGHADEAKQAERFPDMSSPYDRRLLQRAAEIARREEIRVHQGVYVAMSGPNYE 188

Query: 198 TAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAA 257
           T AE R ++ IGGDVVGMS VPEVI AR C L+V+A+S +TN+       ++     + A
Sbjct: 189 TRAEYRFLRNIGGDVVGMSTVPEVIVARQCGLQVLALSTVTNVCLPDDLGRVGKYDVVNA 248

Query: 258 AELSKQNFINLICGFLRK 275
           A+ ++     ++   +R+
Sbjct: 249 AKGAEPKLRRIVREVIRE 266


>UniRef50_B2KC58 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Elusimicrobium minutum Pei191 RepID=B2KC58_ELUMP
          Length = 273

 Score =  295 bits (756), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 97/263 (36%), Positives = 148/263 (56%)

Query: 14  IDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH 73
              I     +F P +A I GSGL     +++N   I Y+ +P F  STV GH+G L+ G 
Sbjct: 11  TAFINKKTKNFKPEIALITGSGLAGSVPELKNKTVIPYKNIPDFLNSTVSGHSGNLIFGT 70

Query: 74  LQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVAL 133
            +G  ++ M+GR H+YEG  +  +  A R   +LG + L  + A GS+  ++  GSL  L
Sbjct: 71  YKGKKLMVMQGRFHYYEGHCIKDIALAPRVMGMLGVKTLMVSAAVGSINAKLTPGSLAVL 130

Query: 134 KDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPG 193
            DHIN M   P++G  D  FG+ F  L+ AYD +   L+   AK+        V+++  G
Sbjct: 131 SDHINLMATNPLIGNYDPAFGQMFVDLSEAYDKKLVKLISSKAKKLKINNAPAVYIAVTG 190

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQ 253
           PNFET +EI+  + +G DVVGMSVV EVI++R   +KV   + +TN+A G+S   LSHA+
Sbjct: 191 PNFETPSEIKAFRTLGADVVGMSVVHEVIASRQAGIKVCGCAWVTNLASGISKTPLSHAE 250

Query: 254 TLAAAELSKQNFINLICGFLRKI 276
           TL+  +  +  F  L+   + ++
Sbjct: 251 TLSETKKIEGKFKTLLENVIPEM 273


>UniRef50_Q311R2 Inosine guanosine and xanthosine phosphorylase n=4
           Tax=Desulfovibrio RepID=Q311R2_DESDG
          Length = 276

 Score =  295 bits (756), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 96/265 (36%), Positives = 132/265 (49%), Gaps = 1/265 (0%)

Query: 13  CIDIIKTYKPDF-TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL 71
             + +K        P+V  +LG+GLG L D +     I Y ++P FP STV  H G  + 
Sbjct: 10  ASEFLKKKLSGHPDPKVGIVLGTGLGGLVDAVSIHTVIDYGEIPDFPRSTVASHQGRFIA 69

Query: 72  GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
           G +   PV+  +GR H YEG     +   +RT    G + L  TNAAG+L P   AG L+
Sbjct: 70  GSIGSTPVLLQQGRCHLYEGYSAGDVCTGVRTMAACGADTLIITNAAGALNPAWSAGDLM 129

Query: 132 ALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSY 191
           A+ DHIN    +P+ G N+D +G RF  ++  YDA+      + A E G  L  GV+   
Sbjct: 130 AITDHINFTGQSPLTGPNNDLWGPRFPDMSAPYDAQLICAAMQKASELGIRLERGVYAGV 189

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH 251
            GP  ET AE RM +  G D VGMS V EVI+ARH  LKV+ VS +TN        +   
Sbjct: 190 RGPQMETPAETRMYKAAGADAVGMSTVLEVIAARHMGLKVLGVSCLTNKNLPDCMQEAPL 249

Query: 252 AQTLAAAELSKQNFINLICGFLRKI 276
            + +  A L+      LI      +
Sbjct: 250 EEVIRVASLAGNRLAKLIAAVTADL 274


>UniRef50_Q1NL01 Inosine guanosine and xanthosine phosphorylase:Purine nucleoside
           phosphorylase I, inosine and guanosine-specific
           (Fragment) n=3 Tax=Deltaproteobacteria
           RepID=Q1NL01_9DELT
          Length = 288

 Score =  293 bits (751), Expect = 3e-78,   Method: Composition-based stats.
 Identities = 97/260 (37%), Positives = 142/260 (54%), Gaps = 2/260 (0%)

Query: 16  IIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQ 75
            ++ + P   P V  +LG+GLG LA  +   V I Y  +P FP +TV GH G LV G L 
Sbjct: 30  YLQQHLP-APPEVVLVLGTGLGQLATMVAEPVQIPYADIPHFPRATVSGHHGNLVCGRLC 88

Query: 76  GVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKD 135
           G  V  M+GR H+YEG     +T  IR   LLG   L  +NAAG L P+   G+L+ + D
Sbjct: 89  GRQVAVMQGRFHYYEGYSARELTMPIRVLSLLGARQLLVSNAAGGLNPQFAPGTLMLIND 148

Query: 136 HINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP-LTEGVFVSYPGP 194
           H+N +P  P+ G N + +GERF  ++ AYD E R    +  +  G   + EG++ + PGP
Sbjct: 149 HLNLIPDNPLRGANIEAWGERFPDMSVAYDRELRGRAWQSVRRLGLERVEEGIYAAIPGP 208

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQT 254
           + ET AE R ++  G D VGMS VPEVI ARH  ++V+ V+ ++N+ +  +   +     
Sbjct: 209 SLETPAETRHLRQCGADAVGMSTVPEVIVARHAGMRVLGVAVVSNVNDPDNFQPIRLTDI 268

Query: 255 LAAAELSKQNFINLICGFLR 274
           +  +E   Q    L+   L 
Sbjct: 269 IRESEACAQRLQQLLWELLA 288


>UniRef50_C3FBK6 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Bacillus thuringiensis serovar monterrey BGSC
           4AJ1 RepID=C3FBK6_BACTU
          Length = 266

 Score =  293 bits (751), Expect = 4e-78,   Method: Composition-based stats.
 Identities = 99/262 (37%), Positives = 152/262 (58%), Gaps = 4/262 (1%)

Query: 15  DIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL 74
           + +K      T + A ++GSGL  + +++E+   I Y ++P F  ST   H GEL+ G+L
Sbjct: 9   EYLKERIISKT-KTAIVIGSGLSGIIEKVEDKNIIPYGEIPEFLHSTAPTHRGELISGYL 67

Query: 75  QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALK 134
            G PVVC+ GR H+YEG  M  + + I+  KLLG E +  TNA+GS+  E+  G LV ++
Sbjct: 68  YGKPVVCLNGRFHYYEGYQMQQVAEYIKVLKLLGIEHIILTNASGSMYQEIVPGDLVVVE 127

Query: 135 DHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGP 194
           DHIN     P+ G ND+ FG RF  ++NAY       ++KV +     L +G +V   GP
Sbjct: 128 DHINFSGLNPLRGKNDESFGPRFVDMSNAYSKRL---IEKVFENSSNGLKKGTYVYGTGP 184

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQT 254
           +FETAAEIR  + +GG +VGMS VPEVI   +C ++V+ +S ++N A G+    +S  + 
Sbjct: 185 SFETAAEIRAFKTLGGTIVGMSTVPEVIMCAYCGIEVLTISCVSNYAPGIPGSNVSDEEL 244

Query: 255 LAAAELSKQNFINLICGFLRKI 276
           +    L++  F  ++     KI
Sbjct: 245 VRVTGLAQDKFSKVLEELFNKI 266


>UniRef50_C1C0Q7 Purine nucleoside phosphorylase n=2 Tax=Caligus RepID=C1C0Q7_9MAXI
          Length = 299

 Score =  293 bits (751), Expect = 4e-78,   Method: Composition-based stats.
 Identities = 97/273 (35%), Positives = 151/273 (55%), Gaps = 10/273 (3%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
             D I     +  P +  I GSGLG++ D +++ V I Y  +P FP +TV  H  ++V G
Sbjct: 21  SADYILGQISN-KPTIGIICGSGLGSIGDAVKDPVIIKYTDIPHFPTTTVGSHRSQMVFG 79

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L G  V+ M+GR HFYEG  +   +  +R   L+G + L  TNA+G  R ++  G L+ 
Sbjct: 80  TLGGAQVMVMQGRFHFYEGHSIHTCSMPVRVMHLVGVKTLISTNASGGTREDLKVGDLLI 139

Query: 133 LKDHINTM----PGTPMVGLN-DDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTE 185
           + DHIN +       P+ G N D+RFG RF ++   YD EY  L +++AK+ G    +  
Sbjct: 140 MTDHINLLGFNGGQNPLGGANHDNRFGTRFVAMNKCYDEEYIKLARQIAKDSGLESIVKS 199

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG-- 243
           GV+    GP++ET AE+R M+I+GGD +GMS V E I AR C ++V ++S ITN+     
Sbjct: 200 GVYAMTGGPSYETPAEVRSMKILGGDCIGMSTVHENIVARQCGMRVFSMSLITNICVSSQ 259

Query: 244 LSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
            S+ K +H + +   +  +++       FL  +
Sbjct: 260 ESEDKATHQEVIEVGQSREESLKIFTFSFLAGM 292


>UniRef50_A9BH77 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=9 Tax=Bacteria RepID=A9BH77_PETMO
          Length = 270

 Score =  293 bits (750), Expect = 5e-78,   Method: Composition-based stats.
 Identities = 93/236 (39%), Positives = 131/236 (55%)

Query: 39  LADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMT 98
           +ADQ+EN   I Y+ +P FP STV GH G LV+G ++G+PV+ +KGR H YEG  +  + 
Sbjct: 33  IADQVENPKVIEYKDIPFFPQSTVVGHEGSLVIGTIEGIPVMILKGRFHAYEGIELKDIV 92

Query: 99  DAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFF 158
             I   K LG + L  TNAAG +      G +V   D IN     P+ G N D FG RF 
Sbjct: 93  FPIYVMKDLGVKGLIITNAAGGINKTFSPGDIVVDVDFINFTFKNPLRGPNLDEFGPRFP 152

Query: 159 SLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVV 218
           SL    D  +   + +  K++   L EG ++   GP++ET +EIRM      D+VGMS +
Sbjct: 153 SLVEPVDKNWVKSVIEKCKKDNIELKEGTYLWTLGPSYETPSEIRMFDKYEADLVGMSTL 212

Query: 219 PEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLR 274
           PEV++A H  LKV++ SA+TNMA G+    L H   L   E  K  F  ++   ++
Sbjct: 213 PEVMAANHVGLKVISFSAVTNMAAGILPQPLKHEDVLRITEKIKGKFEKVVYNAIK 268


>UniRef50_Q05788 Purine nucleoside phosphorylase n=10 Tax=Saccharomycetaceae
           RepID=PNPH_YEAST
          Length = 311

 Score =  292 bits (747), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 107/274 (39%), Positives = 148/274 (54%), Gaps = 23/274 (8%)

Query: 26  PRVAFILGSGLGALADQIEN----AVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVC 81
           PR   I GSGLG ++ ++       V + Y+ +PGF  STV GH+G L+ G + G PVV 
Sbjct: 38  PRTLIICGSGLGGISTKLSRDNPPPVTVPYQDIPGFKKSTVPGHSGTLMFGSMNGSPVVL 97

Query: 82  MKGRGHFYEGRGMTIMTDAIRTFKLLG-CELLFCTNAAGSLRPEVGAGSLVALKDHIN-- 138
           M GR H YEG  +   T  IR    +G    L  TNAAG +  +  A  L+ + DH+N  
Sbjct: 98  MNGRLHGYEGNTLFETTFPIRVLNHMGHVRNLIVTNAAGGINAKYQACDLMCIYDHLNIP 157

Query: 139 -TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF--PLTEGVFVSYPGPN 195
                 P+ G N D  G RF +L++AYD E R LL K  KE     PL EG +    GP 
Sbjct: 158 GLAGQHPLRGPNLDEDGPRFLALSDAYDLELRKLLFKKWKELKIQRPLHEGTYTFVSGPT 217

Query: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN------MAEGLSDVKL 249
           FET AE +M++++GGD VGMS VPEVI ARHC  +V+A+S ITN       A  L +  +
Sbjct: 218 FETRAESKMIRMLGGDAVGMSTVPEVIVARHCGWRVLALSLITNTCVVDSPASALDESPV 277

Query: 250 -------SHAQTLAAAELSKQNFINLICGFLRKI 276
                  +HA+ L   +++  +  NLI   + ++
Sbjct: 278 PLEKGKATHAEVLENGKIASNDVQNLIAAVMGEL 311


>UniRef50_B4D4P3 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Chthoniobacter flavus Ellin428 RepID=B4D4P3_9BACT
          Length = 265

 Score =  291 bits (745), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 94/259 (36%), Positives = 142/259 (54%), Gaps = 6/259 (2%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL 71
             ++++     DF P    +LGSGLG+L ++++  +++ YE++ G PVST  GHAG  V 
Sbjct: 8   LSVEVLPKAVRDFQPEWGIVLGSGLGSLVEEVDAILSLPYEEITGMPVSTAPGHAGRFVF 67

Query: 72  GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
           G L G  V+  +GR H YEGR    +T A+R  + +G   L  TNAAG+L P+   GS +
Sbjct: 68  GRLAGCRVMMAQGRVHLYEGRTADEVTAAVRFMENIGVRRLLLTNAAGTLNPKFEPGSWM 127

Query: 132 ALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSY 191
            L DH+N    +P++G         F  ++  Y  E R      A EEG  L EGV+   
Sbjct: 128 MLNDHLNLTGTSPLLG------APNFADMSAVYSPELRVRFATAAGEEGLVLHEGVYAGL 181

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH 251
            GP +ET AE+RM++++G D VGMS V E I AR   +++ A S +TN A GL    LSH
Sbjct: 182 LGPQYETPAEVRMLRMLGADAVGMSTVLEAIQARALKMEIAAFSCLTNWAAGLGTKPLSH 241

Query: 252 AQTLAAAELSKQNFINLIC 270
            + +    ++    + ++ 
Sbjct: 242 EEVIETGRVASAQMLRILT 260


>UniRef50_C0BWU4 Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM
           15053 RepID=C0BWU4_9CLOT
          Length = 276

 Score =  290 bits (743), Expect = 3e-77,   Method: Composition-based stats.
 Identities = 103/267 (38%), Positives = 143/267 (53%), Gaps = 7/267 (2%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
             + I+  K    P V  +LG+ LG +  +I +   I Y+++P F +ST  GHAG+LV G
Sbjct: 13  SAEYIRE-KIGTPPAVGIVLGTCLGEIEHEITDKTEIYYKEIPNFLISTAPGHAGKLVCG 71

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L G  V+CM GR H YEG     +   +  FKLLG   L  TNAAG++      G +  
Sbjct: 72  RLGGKRVLCMAGRFHHYEGYSFEELRIPVYVFKLLGIRTLILTNAAGAVNLNYETGDICV 131

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           +KDHIN    +P  G N    GERFFS+ + Y    R L +  A E GF L EGV+   P
Sbjct: 132 IKDHINLCGVSPQRGENIPELGERFFSMNDVYTPSLRRLAKDAAVELGFSLQEGVYYFAP 191

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH- 251
           GP FET AEIR M+++G D+VGMS VPE I+A HC + V+ +S  TN++    D  L H 
Sbjct: 192 GPQFETPAEIRAMRLLGADMVGMSTVPEAITAAHCRMDVLGLSLATNLSA---DRVLDHD 248

Query: 252 --AQTLAAAELSKQNFINLICGFLRKI 276
                    ++    F  L+   + ++
Sbjct: 249 VTEDVNNVEDVVSGRFRALLTKIVSRL 275


>UniRef50_Q11C51 Inosine guanosine and xanthosine phosphorylase family n=10
           Tax=Alphaproteobacteria RepID=Q11C51_MESSB
          Length = 268

 Score =  289 bits (741), Expect = 5e-77,   Method: Composition-based stats.
 Identities = 114/265 (43%), Positives = 159/265 (60%), Gaps = 3/265 (1%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            IDI+        PR+A +LGSGLGALAD++   V I Y  LPGFP+S V GHAGELV G
Sbjct: 4   TIDILIERLNGLAPRLAIVLGSGLGALADELTKPVHIPYADLPGFPLSGVSGHAGELVAG 63

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
           +   VPV+ + GR H+YE      M  A+     +G   +  TNAAGSL+ ++ AGS++ 
Sbjct: 64  YFGSVPVIMLAGRSHYYEHGNAAAMRPALEVLAGIGVTAIILTNAAGSLQVDMPAGSVML 123

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           ++DHIN     P++G   +    RF  ++ AYD + R  L++ A + G  L +GV++ + 
Sbjct: 124 VEDHINYSGMNPLIGEQSE---ARFVGMSAAYDRDLRDALERAASKAGETLHKGVYMWFS 180

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP+FET AEIRM +++G D VGMS VPEVI AR   L+V A S ITN+A GL   +LSH 
Sbjct: 181 GPSFETPAEIRMARMLGADAVGMSTVPEVILARFLGLRVAACSVITNLAAGLGAGELSHD 240

Query: 253 QTLAAAELSKQNFINLICGFLRKIA 277
           +T   A +       ++  F+R  A
Sbjct: 241 ETKDMAPVGGGKLAKILTQFMRDSA 265


>UniRef50_Q472Z5 Purine nucleotide phosphorylase:Inosine guanosine and xanthosine
           phosphorylase n=1 Tax=Ralstonia eutropha JMP134
           RepID=Q472Z5_RALEJ
          Length = 287

 Score =  289 bits (739), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 151/265 (56%), Positives = 189/265 (71%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +  I+ +  +F P++  ILGSGLG LA  IENA+AI Y  LPGFP S V GHAGE+VLG
Sbjct: 18  AVQRIRQHVGEFRPQIGLILGSGLGGLARAIENAIAIPYAALPGFPQSLVEGHAGEVVLG 77

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L GV ++CM+GR HFYEG G T MT A+RT K +GC+ LF T AAGSL PE+  G LVA
Sbjct: 78  RLGGVELMCMRGRQHFYEGHGTTGMTQAVRTMKRMGCDRLFVTCAAGSLHPELEPGRLVA 137

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           +KDHIN +PG P++G NDD+ G RF S+ANAYD   R  LQ VA+  G P  EGV+V++ 
Sbjct: 138 IKDHINLLPGNPLIGPNDDQIGPRFCSMANAYDTVLRQGLQDVAQALGLPWAEGVYVAFS 197

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP FETAAEIRMMQ+IGGDVVGMS VPEVISARHC L+V+A++ ITN+ EG+ +  LSH 
Sbjct: 198 GPTFETAAEIRMMQVIGGDVVGMSTVPEVISARHCGLRVLAIACITNLGEGIGNEVLSHE 257

Query: 253 QTLAAAELSKQNFINLICGFLRKIA 277
            TL    ++  +   LI G+  + A
Sbjct: 258 LTLQYGSMALVDLQRLIVGWFEQQA 282


>UniRef50_A9URE9 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9URE9_MONBE
          Length = 311

 Score =  288 bits (738), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 107/280 (38%), Positives = 149/280 (53%), Gaps = 12/280 (4%)

Query: 9   NPLFCIDIIKTYKPD--FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHA 66
           N     D +K  +      P +  I GSGLG LA ++++AV I YE++P FPVSTV GH 
Sbjct: 23  NFDLVEDAVKHIQTKAKTQPLIGIICGSGLGGLAAEVQDAVTIGYEEIPNFPVSTVAGHE 82

Query: 67  GELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVG 126
           G+LV G L G PVV MKGR H YEG   + +   IRT   LG + LF TNAAG L     
Sbjct: 83  GKLVFGTLGGAPVVVMKGRLHCYEGYAFSRIAVPIRTLCALGIKYLFVTNAAGGLNESFE 142

Query: 127 AGSLVALKDHINTMP---GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF-- 181
            G L+ L+DH+N        P+VG +DDR+G RF  ++  YD + R + ++         
Sbjct: 143 VGDLMMLEDHLNFPGFAVQNPLVGPHDDRYGARFVPMSKPYDRKLRDIFKQTIDGMSMAG 202

Query: 182 ---PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
              P   GV+    GP +E+ AE R ++  G D VGMS VPEVI A    +K +A+S IT
Sbjct: 203 LHSPFRTGVYAMVGGPTYESPAEARFIKSAGADAVGMSTVPEVIVAIQQGVKCLAMSLIT 262

Query: 239 NMAE--GLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           N        D + +HA+ L A++  + +   L     + +
Sbjct: 263 NKVVLKIDDDNEPNHAEVLEASQARQPDVQRLFVALSKNV 302


>UniRef50_A9G8Q6 DeoD protein n=8 Tax=Bacteria RepID=A9G8Q6_SORC5
          Length = 283

 Score =  287 bits (736), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 90/238 (37%), Positives = 133/238 (55%)

Query: 39  LADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMT 98
             D++   V + Y  +PG P   V GH G L  G +  V V C++GR H YEG  +  + 
Sbjct: 35  WGDELAELVKVPYADIPGMPRPAVAGHPGFLCAGRVGDVQVACLQGRAHVYEGHPLAKVV 94

Query: 99  DAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFF 158
             +R    LGC  +  TNAAG + P   AG L+ L DH+N M   P+VG ND+  G+RF 
Sbjct: 95  FGVRVLARLGCRAVLLTNAAGGINPGFAAGDLMLLTDHLNLMGANPLVGPNDEALGKRFP 154

Query: 159 SLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVV 218
            +  A+D     L +  A + G  L EGV+ +  GP +ET AEIRM++ +G D VGMS V
Sbjct: 155 DMTYAHDPRLLELAKTAASDAGVALREGVYAALLGPTYETPAEIRMLRTLGADAVGMSTV 214

Query: 219 PEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           PE+I+ RH  +   A+S +TN+A GL+  +L H +    A  ++  F  L+  ++R++
Sbjct: 215 PEIIALRHMGVPAAAISCVTNLAAGLTKRELDHKEVEETAREARARFTALLSAWVRRV 272


>UniRef50_B6K0G6 Purine nucleoside phosphorylase n=1 Tax=Schizosaccharomyces
           japonicus yFS275 RepID=B6K0G6_SCHJY
          Length = 319

 Score =  285 bits (729), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 102/302 (33%), Positives = 149/302 (49%), Gaps = 26/302 (8%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDF--TPRVAFILGSGLGALADQIENAV-AISYEKLPGF 57
           +   +   N     + +    P     PRVA + GSGLG+LA+ +      I Y  +PGF
Sbjct: 18  IPHSETYKNAQLAREYVLANVPGELAKPRVAVVCGSGLGSLAENLFGPKFVIPYSDIPGF 77

Query: 58  PVSTVHGHAGELVLGHLQG--VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCT 115
               + GHA  L+   +    VP +   GR H YEG  + ++T   R  K++G E++  T
Sbjct: 78  VACHIPGHASRLIFAFIGENKVPCMIFAGRFHSYEGHALDVVTFPQRFMKIMGVEVMIAT 137

Query: 116 NAAGSLRPEVGAGSLVALKDHINT---MPGTPMVGLNDDRFGERFFSLANAYDAEYRALL 172
           NAAG L      G L+ +KDHIN        P+ G N D FG RF  L++AYD E R L+
Sbjct: 138 NAAGGLNSNYKVGELMIIKDHINFPGLAGLNPLKGPNLDDFGTRFPPLSDAYDLELRKLV 197

Query: 173 QKVAKEEGFP--LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLK 230
            K A E      + EG +    GP+FET AE RM++++G D VGMS VPEVI ARHC ++
Sbjct: 198 YKAATERDVHRTINEGCYAFVSGPSFETRAEARMLKLLGADCVGMSTVPEVIVARHCGIR 257

Query: 231 VVAVSAITNM----------------AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLR 274
           V+A+S +TN                    +S    +H + L A   + ++   L+   + 
Sbjct: 258 VLAISLVTNNVVTEESPSALSTPDADTSIMSKGAANHKEVLEAGLAAAEDMRILVTTVIN 317

Query: 275 KI 276
            +
Sbjct: 318 HL 319


>UniRef50_B1GZW7 Purine nucleoside phosphorylase n=1 Tax=uncultured Termite group 1
           bacterium phylotype Rs-D17 RepID=B1GZW7_UNCTG
          Length = 281

 Score =  285 bits (729), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 89/252 (35%), Positives = 134/252 (53%)

Query: 23  DFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM 82
           DF P  A I GSGLG ++ Q      I Y  +P F  + V GHAG+L+L       ++  
Sbjct: 21  DFNPTTAVIAGSGLGEISKQFTIRKTIKYSDIPYFLKTAVQGHAGDLLLCSYGSADLLIF 80

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            GR H+YEG     +   +R  K LG + L  T A G L  +   G ++ LKDHI+    
Sbjct: 81  NGRFHYYEGHHPQEVVYPVRVMKFLGIKTLVITAATGGLNKKYSVGDIIVLKDHIDCTGN 140

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEI 202
            P++G++ D FGERF ++ N YDA  R     +AK+      EG++    GP++ET A +
Sbjct: 141 NPLIGVHYDEFGERFPNMENVYDAVLRKKALSLAKKFKIKACEGIYFGVSGPSYETPASV 200

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
           +  QI+GGDVVGMSVV E   A    ++V+ ++ ++NMA G+ +  LSHA+ +   E   
Sbjct: 201 KAYQILGGDVVGMSVVYEATVAAQMKMRVLGLAYVSNMAAGIHNRPLSHAEVIENGEKVS 260

Query: 263 QNFINLICGFLR 274
            +   +    + 
Sbjct: 261 LSMSKIAKNIIS 272


>UniRef50_C5NWB5 Purine nucleoside phosphorylase 1 n=1 Tax=Gemella haemolysans ATCC
           10379 RepID=C5NWB5_9BACL
          Length = 274

 Score =  282 bits (722), Expect = 8e-75,   Method: Composition-based stats.
 Identities = 92/252 (36%), Positives = 134/252 (53%), Gaps = 7/252 (2%)

Query: 29  AFILGSGLGALADQIENAVAISYEKLPGFP----VSTVHGHAGELVLGHLQGVPVVCMKG 84
           A +LGSG   +  ++E+   + YE +P FP     + V GHA +L  G + G  V+ + G
Sbjct: 25  AVVLGSG---ITLELEDQQELGYEAIPLFPGNKHANRVKGHANKLTFGKISGKNVLVLNG 81

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H+YEG  M  +       K LG + LF TNA G++      G +V L D I+ +   P
Sbjct: 82  RLHYYEGYSMKDVAFMTYVVKHLGVKGLFITNACGAINTNFREGDIVCLDDFISLVSNNP 141

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           ++G N+ R GERF  +   +D+     L K AK+    L  GV+  + GP FET AEIR 
Sbjct: 142 LMGENEPRLGERFVDMTTPFDSYLVENLHKSAKKLDITLHTGVYGFFQGPYFETRAEIRA 201

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
            + +G D+VGMS VPEVI+A H  L V  ++  TNMA G+ + K  H   L  A+   +N
Sbjct: 202 FKTMGCDLVGMSTVPEVIAANHASLPVAVLACATNMATGIQEKKHDHEHVLQTAQKISEN 261

Query: 265 FINLICGFLRKI 276
              L+   L+ +
Sbjct: 262 LKKLLIETLQNL 273


>UniRef50_Q9UTG1 Putative purine nucleoside phosphorylase n=4 Tax=Ascomycota
           RepID=PNPH_SCHPO
          Length = 315

 Score =  281 bits (720), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 103/292 (35%), Positives = 144/292 (49%), Gaps = 26/292 (8%)

Query: 11  LFCIDIIKTYKPDF--TPRVAFILGSGLGALADQIENAV-AISYEKLPGFPVSTVHGHAG 67
           L   + I    P+    P+VA I GSGLG LA  +   V  + YE +P F VS V GHA 
Sbjct: 24  LEAREYIIEQVPEELSKPKVAIICGSGLGTLASGLSAPVYEVPYEDIPHFHVSHVPGHAS 83

Query: 68  ELVLGHLQGVPV--VCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
           +L    L    V  + + GR H YEG  +   T  +R  K++G E++  TNAAG L    
Sbjct: 84  KLYFAFLGEKRVPTMILAGRYHSYEGYPIEATTFPVRLMKVMGVEVMVVTNAAGGLNQGF 143

Query: 126 GAGSLVALKDHINT---MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAK--EEG 180
             G L+ LKDHIN        P+ G N   FG RF  L++AYD E R L+   AK  +  
Sbjct: 144 KVGDLMILKDHINFPGLAGMNPLRGPNAHEFGVRFPPLSDAYDLELRKLVYDAAKAHKVS 203

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
             + EG +    GP FET AE RM+ ++G D VGMS VPEV+ ARHC ++V+A+S +TN 
Sbjct: 204 RTIHEGCYAFVSGPCFETRAESRMLALMGADCVGMSTVPEVVVARHCGIRVLAISLVTNN 263

Query: 241 ----------------AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
                           +  +S    +H + L     +  +   ++   +  I
Sbjct: 264 VVVEESPSAKDLVEVDSNVMSKGAANHLEVLEVGIAAAADVRTMVETIVNFI 315


>UniRef50_B8J4B5 Inosine guanosine and xanthosine phosphorylase family n=7
           Tax=Desulfovibrionales RepID=B8J4B5_DESDA
          Length = 303

 Score =  279 bits (715), Expect = 6e-74,   Method: Composition-based stats.
 Identities = 94/263 (35%), Positives = 139/263 (52%), Gaps = 9/263 (3%)

Query: 23  DFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH--------- 73
           D +  V  +LG+GL  LAD++   VA+ Y  LPGFPVS+V  H G  V G          
Sbjct: 41  DNSVPVGLVLGTGLSGLADRLAERVAVPYADLPGFPVSSVDSHVGAFVWGRFPSSCGEDD 100

Query: 74  LQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVAL 133
           + G PV+  +GR H YEGR    +   +R    +G + L  TNAAG+L P   AGS++ +
Sbjct: 101 VPGRPVLIQQGRCHLYEGRSPAEVCMGVRVMAAMGVKTLVITNAAGALNPHFDAGSIMCM 160

Query: 134 KDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPG 193
            D IN    +P++G N +++G RF  ++  +DA+ R L  + +   G  L  GV++   G
Sbjct: 161 SDFINHTGYSPLLGCNCEQWGPRFPDMSAPFDADLRTLAMETSARLGLRLERGVYIGVRG 220

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQ 253
           P  ET AE RM +  G D VGMS V EVI+ARH  ++V+ +S I+N             +
Sbjct: 221 PEMETPAETRMYRQWGADAVGMSTVLEVIAARHLGMRVLGLSCISNKNLPDCMTPAPLEE 280

Query: 254 TLAAAELSKQNFINLICGFLRKI 276
            +  A  + +N   LI   + K+
Sbjct: 281 IILVAAQAGKNLGRLIRAMMTKL 303


>UniRef50_B3QTH8 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Chloroherpeton thalassium ATCC 35110
           RepID=B3QTH8_CHLT3
          Length = 292

 Score =  278 bits (712), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 91/263 (34%), Positives = 138/263 (52%), Gaps = 4/263 (1%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +  I ++       VA +LGSGLGA A +++   +    ++P FP  +V GH G +  G
Sbjct: 30  AVKHIHSHCDVPKNTVAIVLGSGLGAFASRVKVYHSFKTSEIPHFPTPSVEGHGGRVTFG 89

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L   PV  ++GR H YEG  +  +T  +   + LG ++L  TN+AG + P+   G L  
Sbjct: 90  TLGDRPVALIEGRVHLYEGWPVEWVTFYVEILRQLGIKVLILTNSAGGINPDFNVGDLCL 149

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           ++DHIN M  T +         E        YD +   ++ + A E    L +GV+    
Sbjct: 150 IRDHINFMFETRLNRYG----MEPRLRHVGFYDKDLSEVIYRTANECKITLRQGVYAGVK 205

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP +ET AEIRM+Q  G D+VGMS VPEV++A    ++V AVS +TN A G+S+ KLSH 
Sbjct: 206 GPCYETKAEIRMLQACGADLVGMSTVPEVVAANFHHMRVAAVSLVTNKATGISECKLSHD 265

Query: 253 QTLAAAELSKQNFINLICGFLRK 275
                AE +++ F   +   + K
Sbjct: 266 DVKKTAESAREKFDYFLEMVINK 288


>UniRef50_C7NVB1 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Halorhabdus utahensis DSM 12940 RepID=C7NVB1_HALUD
          Length = 275

 Score =  278 bits (712), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 94/253 (37%), Positives = 137/253 (54%), Gaps = 1/253 (0%)

Query: 24  FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
            TP  A ILGSGLG + D++E  +++ YE +P    STV GHAG  V+G +  V V+ M 
Sbjct: 18  LTPETAMILGSGLGGMTDEMEIELSVPYEDVPTLEASTVEGHAGRFVVGTVGEVSVLGMD 77

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           GR H+YE   M  +   IR    LGCE L  TNAAG +  +   G ++ ++DHIN     
Sbjct: 78  GRVHYYETGDMDPIVAPIRALGELGCERLLITNAAGGINADYEPGDVMLIEDHINMQGTN 137

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEI 202
           P++G      G  F  + NAY  +  A  + +A +    + + GV+   PGP++ET AEI
Sbjct: 138 PLIGRAGLGDGPMFPDMTNAYSPDLLAAARDLAADSSLTIHDGGVYAGMPGPSYETPAEI 197

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
            M+  +G D VGMS VPEVI A    + VV +S ITN A G+    LSH + +   +  +
Sbjct: 198 EMLDTVGADAVGMSTVPEVIVANQLGMDVVGMSTITNYAAGVVGDPLSHEEVVETIKTIE 257

Query: 263 QNFINLICGFLRK 275
            +    +   L++
Sbjct: 258 DDLRTYVTALLQR 270


>UniRef50_Q2S0P3 Purine nucleoside phosphorylase n=1 Tax=Salinibacter ruber DSM
           13855 RepID=Q2S0P3_SALRD
          Length = 262

 Score =  274 bits (700), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 87/252 (34%), Positives = 137/252 (54%), Gaps = 1/252 (0%)

Query: 24  FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
           + P +A ILGSGLG LA+  +    +   ++PG+P STV GH+G+LV G L+   VV ++
Sbjct: 7   WAPEMALILGSGLGRLAEAADETTVVPAAEIPGYPESTVEGHSGKLVFGALEDTRVVFVQ 66

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           GR H YEG  +  +   +R    LG + +  TN+AG +      G+L+ +  H+N    +
Sbjct: 67  GRVHLYEGYPVQKIAMPVRLVHALGADRMLVTNSAGGINRTFDPGTLMFITSHLNMAFAS 126

Query: 144 PMVGLNDDRFGERF-FSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEI 202
           P VG       +R     A  Y+  + +  ++VA + G     G +    GP++ET AE+
Sbjct: 127 PGVGAGAGPARQRSDEEQAPFYEPGWTSRAEQVALDLGLDARRGTYAWTLGPSYETKAEV 186

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
           R ++ +G D VGMS VPEVI A    + V+ +S ITN A GL+   L H + L  +E  +
Sbjct: 187 RALEQLGADAVGMSTVPEVIQAHQLGMAVLGLSTITNPAAGLAPGGLDHDEVLEVSERVR 246

Query: 263 QNFINLICGFLR 274
            + + L+ G +R
Sbjct: 247 GDLMKLVRGIVR 258


>UniRef50_B7GAT6 Predicted protein (Fragment) n=2 Tax=Bacillariophyta
           RepID=B7GAT6_PHATR
          Length = 262

 Score =  273 bits (698), Expect = 5e-72,   Method: Composition-based stats.
 Identities = 90/262 (34%), Positives = 133/262 (50%), Gaps = 11/262 (4%)

Query: 26  PRVAFILGSGLGALADQIENAV-AISYEKLPGFPV-STVHGHAGELVLGHLQGVPVVCMK 83
           P V  I GSGL  LA  ++     + Y  +PGFP   TV GH GE+V G + GV  +C +
Sbjct: 1   PTVGIICGSGLSGLAATLDGPTLTVPYADIPGFPAHCTVAGHKGEVVFGSIHGVQAICFR 60

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN---TM 140
           GR H YEG  M  +   +   + L  +++  TNAAG L P+   G +VA+ DH+      
Sbjct: 61  GRFHSYEGHDMKTVVLPVYVMRCLDTKIVIITNAAGGLNPDYNVGDVVAVSDHLALPQLA 120

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP---LTEGVFVSYPGPNFE 197
              P++G NDD  G RF + ++AY    R      A+           G +    GP +E
Sbjct: 121 GKNPLIGPNDDELGPRFPATSDAYPDALRIAATHAAESLNMQEYWHPHGTYCFVSGPMYE 180

Query: 198 TAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDV---KLSHAQT 254
           + AE R+++ +GGD VGMS +PEV++A HC+LKV+ +S ITN      D      +HA+ 
Sbjct: 181 SKAECRLLRTLGGDAVGMSTIPEVVAAHHCELKVLCLSLITNKVVMEGDEGATVATHAEV 240

Query: 255 LAAAELSKQNFINLICGFLRKI 276
           L A +        L+   +  +
Sbjct: 241 LEAVQARSVQMQTLVKEIVANL 262


>UniRef50_Q11M20 Inosine guanosine and xanthosine phosphorylase family n=2
           Tax=Alphaproteobacteria RepID=Q11M20_MESSB
          Length = 279

 Score =  270 bits (691), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 92/250 (36%), Positives = 130/250 (52%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
            V  ILGSGLG LA  +++A  I Y ++  FPV T  GH G+LV+G L G  V  M+GR 
Sbjct: 25  EVGIILGSGLGDLAQSVDDAEVIPYTEIEAFPVPTAPGHKGQLVIGTLHGRRVAVMQGRL 84

Query: 87  HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
           H YEGR    +       K LG   L  TNAA  L P    G ++ ++DH+N     P+V
Sbjct: 85  HLYEGRSPQDIALGPYLLKRLGSASLIVTNAASGLHPAYRPGDVMLIEDHLNFTGLNPLV 144

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQ 206
           G N    G RF  ++ AYD     L ++ A+    P+ +G++    GP+ ET AE R ++
Sbjct: 145 GSNSPEIGLRFPDMSRAYDPALLDLAEEAAERALQPVHKGIYGGILGPSLETLAERRFLR 204

Query: 207 IIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFI 266
             G D VGMS V EVI+A H  L+V+ +SAITN A        +  + L +A    +   
Sbjct: 205 ASGCDAVGMSTVTEVIAAVHGGLRVIGISAITNTAAIGDRRTDTIEEALTSAANCAEKID 264

Query: 267 NLICGFLRKI 276
            ++   L  +
Sbjct: 265 AILRQLLPLL 274


>UniRef50_C5P2F4 Purine nucleoside phosphorylase, putative n=2 Tax=Coccidioides
           RepID=C5P2F4_COCP7
          Length = 344

 Score =  266 bits (681), Expect = 6e-70,   Method: Composition-based stats.
 Identities = 110/342 (32%), Positives = 156/342 (45%), Gaps = 70/342 (20%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPD--FTPRVAFILGSGLGALADQIENA--VAISYEKLPG 56
           M++          ++ +K + P+   TPRVA I GSGLG LAD I++   V   Y  +P 
Sbjct: 1   MAESSMFKQAQAALNYLKPHLPEALRTPRVAVICGSGLGGLADTIDSKAKVEFDYRDIPN 60

Query: 57  FPVSTVHGHAGELVLGHLQG-VPVVCMKGRGH---------FYEGRGMTIMTDAIRTFKL 106
           FP STV GH G+LV G+L    P V M GR           FYEG  +  +T  +R FKL
Sbjct: 61  FPASTVPGHLGKLVFGYLGAETPAVLMVGRAQEIEADTAASFYEGHSIDKVTFPVRLFKL 120

Query: 107 LGCELLF----------------------CTNAAGSLRPEVGAGSLVALKDHI---NTMP 141
           LG E++                        TNA+G L  E   G +V + DHI       
Sbjct: 121 LGVEIMIGTGNEHLLGKHKIQSPTKQLCTVTNASGGLNSEYAVGDVVLINDHIFLAGLAG 180

Query: 142 GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAK-----EEGFPLTEGVFVSYPGPNF 196
             P+ G N+D FG RF +L++AYD E R    +        E    + EGV+    GP  
Sbjct: 181 LHPLRGPNEDEFGVRFPALSDAYDLELRRTAHRAWTKVIRVESKRRIHEGVYAFCAGPR- 239

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAE-------------- 242
              AE R ++ +G D+VGMS VPE+I ARHC L+V+A+S +TN A               
Sbjct: 240 ---AECRFLRQLGADLVGMSTVPEIIVARHCGLRVLALSLVTNNAVLTPVPRGDDRLLQE 296

Query: 243 --------GLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
                    + + K +H + L A   +  +   L+   +  +
Sbjct: 297 TERAQLNRIVEEGKANHEEVLKAGSQAAADVQKLVRQVVLDM 338


>UniRef50_B4MDV7 GJ18292 n=4 Tax=Drosophila RepID=B4MDV7_DROVI
          Length = 325

 Score =  265 bits (679), Expect = 8e-70,   Method: Composition-based stats.
 Identities = 92/261 (35%), Positives = 133/261 (50%), Gaps = 7/261 (2%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           + +  P+   + GS L  L D IEN + I Y  +P FP  T+H H G+L +G L G  V+
Sbjct: 63  RSETRPKFGLVCGSNLDTLTDLIENPIVIDYSDIPKFPDCTIHDHKGKLFVGTLMGATVI 122

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
            ++GR H YEG  +   +  +R  KL G E +  T AAG++      G ++ +KDHIN  
Sbjct: 123 ALQGRFHHYEGNSLASCSMPVRVLKLCGIEYMILTCAAGAVNKNYKVGDIMLIKDHINMF 182

Query: 141 PG---TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG--FPLTEGVFVSYPGPN 195
                 P+ G ND RFG+R   +A+AYD        ++  E G    +  GV+    GP 
Sbjct: 183 GWFGNNPLNGPNDLRFGDRHVIMADAYDEGLIEKALEIGLEIGQEDRMHLGVYACLGGPV 242

Query: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL 255
           +ETA E R ++ IG D VGMS+V EVI ARHC LKV + S I+       D+  S     
Sbjct: 243 YETATEQRFLRSIGVDAVGMSLVQEVIYARHCGLKVFSFSLISMPPIEQPDMPESVRDV- 301

Query: 256 AAAELSKQNFINLICGFLRKI 276
            +    +   + L+   + KI
Sbjct: 302 -SIHQGQIVCMELLSRMIYKI 321


>UniRef50_B8ICG2 Purine nucleotide phosphorylase n=28 Tax=Alphaproteobacteria
           RepID=B8ICG2_METNO
          Length = 286

 Score =  265 bits (678), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 102/247 (41%), Positives = 135/247 (54%), Gaps = 3/247 (1%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +A + G+GLG LA +IE    + Y ++P FPVS V GHAG+LV G L G PV+  +GR H
Sbjct: 36  LAVVAGTGLGPLAARIEAPRILPYAEIPHFPVSGVSGHAGQLVAGDLGGRPVLLFQGRAH 95

Query: 88  FYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG 147
            YE      M   +     LG   L  TNAAGSLR E G G L  + DH+N     P++G
Sbjct: 96  AYEQGDAAAMRVPLGVLAALGAPPLLLTNAAGSLRHEAGPGRLALITDHLNLSGLNPLIG 155

Query: 148 LNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQI 207
            + +    RF  + +AYD   R  L   A      L EGV+  + GP+FET AEIRM   
Sbjct: 156 EHSE---ARFVPMVDAYDPGLRKSLHGAAAAADLVLHEGVYAWFLGPSFETPAEIRMAGR 212

Query: 208 IGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFIN 267
           +G D+VGMS VPEVI AR   L+V A+S +TN A G       HA+T   A  + ++   
Sbjct: 213 LGADLVGMSTVPEVILARFFGLRVAALSIVTNYAAGFDGGAPHHAETKRVAAAAAEDVGR 272

Query: 268 LICGFLR 274
           L+  +L 
Sbjct: 273 LLAVWLA 279


>UniRef50_Q3A2Z8 Xanthosine phosphorylase n=1 Tax=Pelobacter carbinolicus DSM 2380
           RepID=Q3A2Z8_PELCD
          Length = 273

 Score =  262 bits (669), Expect = 1e-68,   Method: Composition-based stats.
 Identities = 87/246 (35%), Positives = 129/246 (52%), Gaps = 4/246 (1%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
            +A ILGSGLG +AD +E+     Y     FP   V GHAG L+ G L G  V+  +GR 
Sbjct: 27  DLALILGSGLGQVADAVEDVKVWEYRDFSCFPAVAVAGHAGRLLAGTLHGRRVLIFQGRF 86

Query: 87  HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
           H Y+G         +R    LGC  L  TNA G + P++ AG  + + DHIN +   P+ 
Sbjct: 87  HLYQGLTAWQTAVPVRLAHALGCRRLLLTNAVGGIHPDLDAGCFMFVADHINVLGDNPLR 146

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQ 206
           G+     G+ F  L+  Y  +    L+  A      + +GV  + PGP++ET AE+R ++
Sbjct: 147 GM----CGDTFVDLSRLYRTDLFKSLRTEALSHNIHVQQGVLAAVPGPSYETPAEVRALR 202

Query: 207 IIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFI 266
            +G D V MS++PE I A    L+VV +S++TN A GL   +L H + LA+   + +N  
Sbjct: 203 QMGADAVSMSLIPEAIMAGALGLEVVGLSSVTNRAAGLGTKRLCHDEVLASGSNTAKNLS 262

Query: 267 NLICGF 272
            L+   
Sbjct: 263 VLVASL 268


>UniRef50_D2QX63 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Pirellula staleyi DSM 6068 RepID=D2QX63_9PLAN
          Length = 279

 Score =  261 bits (668), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 102/279 (36%), Positives = 156/279 (55%), Gaps = 5/279 (1%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           M+ +    +       I+ +  + TPRVA ILG+GLG LA +IE A  I Y+++PGFP S
Sbjct: 1   MNPLLSRASIALAAAEIRKHYTE-TPRVAVILGTGLGGLASEIEAAAEIPYKQIPGFPHS 59

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           T   H G L+LG+L G+P   + GR HFYEG  +  +       + LGC+ L  +NAAG 
Sbjct: 60  TAPAHKGRLLLGNLLGLPCAMLAGRCHFYEGYQLEQLMFPTLVMRELGCQYLIVSNAAGG 119

Query: 121 LRPEVGAGSLVALKDHINTM--PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE 178
           + P    G ++ + DHIN M   G+  V        ERF    + YD    ++ +  A +
Sbjct: 120 VNPLYETGDVMLMDDHINLMYFKGSVAVPAASPERVERF--QEHLYDRALLSMAESAAIQ 177

Query: 179 EGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
           EGF    GV+V+  GP +ET AE R+ + IGGDVVGMS VPEV++A    ++V+ +S +T
Sbjct: 178 EGFIPKRGVYVAVSGPTYETRAEYRLFRRIGGDVVGMSTVPEVLAATSVGMRVMGISTVT 237

Query: 239 NMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           N+A+  +   +S  + +  AE  +    +++ G + +IA
Sbjct: 238 NVAKPDAMQTVSSDEVIDVAERVQHKVRSIVRGVIERIA 276


>UniRef50_D2L8K6 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Desulfovibrio sp. FW1012B RepID=D2L8K6_9DELT
          Length = 300

 Score =  259 bits (663), Expect = 6e-68,   Method: Composition-based stats.
 Identities = 92/275 (33%), Positives = 135/275 (49%), Gaps = 26/275 (9%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQ------------ 75
           V  + G+GLG +A ++E+   ++   +PGFP +T  GHAG LV G +             
Sbjct: 26  VGLVAGTGLGGIAGKLEHCRDMATGDIPGFPAATAPGHAGRLVYGTMGTACPPGDPQGSI 85

Query: 76  --------------GVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSL 121
                           PV  + GR H YEG     +   +R    LG   L  TNAAG+L
Sbjct: 86  EETMPAAGAGPDGSSRPVALLSGRLHLYEGHSPRDVAFGVRLLAALGVRQLILTNAAGAL 145

Query: 122 RPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF 181
            P   AG L+ + DH+N     P+VG NDD  G RF  ++ AY     A+    A   G 
Sbjct: 146 DPHFTAGGLMRVTDHLNLTGRNPLVGPNDDALGPRFPDMSRAYSPRLGAVADACALSLGL 205

Query: 182 PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA 241
            L  GV+    GP+ ET AE RM++++G D VGMS V EVI+ARH  ++V+AVS +TN+ 
Sbjct: 206 RLERGVYAGVLGPSLETPAETRMLRLLGADAVGMSTVTEVIAARHLGMEVLAVSCLTNVN 265

Query: 242 EGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
                 + +    LA A+ ++ +   L+   +  +
Sbjct: 266 LPDCMAETTLEAVLATAKRAEGDLARLLAAVIPAV 300


>UniRef50_B0D4C6 Predicted protein n=3 Tax=Agaricales RepID=B0D4C6_LACBS
          Length = 315

 Score =  259 bits (661), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 100/301 (33%), Positives = 139/301 (46%), Gaps = 37/301 (12%)

Query: 13  CIDIIKTYKPD--FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
            ++ I ++ P     P +  I GSGL  LA+     V + YE +PGF  S+V GH   L 
Sbjct: 12  TLEAITSFLPLNLQRPNLGIICGSGLSGLAEDFRQVVIVPYEMIPGFGHSSVPGHKSALA 71

Query: 71  LGHLQ---GVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGA 127
            G L    GVPVV M GR H YEG  M+ +   +R    LG + L  TNAAGSL P +  
Sbjct: 72  FGLLGPGEGVPVVAMLGRFHPYEGHSMSTVIFPVRVMAKLGIKDLIITNAAGSLNPNIPV 131

Query: 128 GS----LVALKDHI---NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           G+    LV ++DHI   N     P++G        RF  L+NAY    R L    A +  
Sbjct: 132 GTRKSFLVVIQDHIALPNLTGMNPLLGPQISSDVPRFLPLSNAYSPSLRRLAFLAAHQLS 191

Query: 181 F---PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAI 237
                L EG +    GP +ET AE R+++  G DVVGMS +PEV++AR   LKV+ +S +
Sbjct: 192 LDRSALAEGTYAWVSGPTYETPAEGRLLRNAGADVVGMSTIPEVLAAREAGLKVMVLSLV 251

Query: 238 TNMA--------------EGLSDVKL--------SHAQTLAAAELSKQNFINLICGFLRK 275
           TN                  LS   +        SH + L   +      + L+   +  
Sbjct: 252 TNFVVIPNEYRSLREEVEAELSGKPIEIPVVQTVSHEEVLLIGKEKATVMMKLVEKVVEL 311

Query: 276 I 276
           +
Sbjct: 312 L 312


>UniRef50_B9ZYX1 Nucleoside phosphorylase n=1 Tax=Dicyema japonicum
           RepID=B9ZYX1_9METZ
          Length = 282

 Score =  254 bits (648), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 91/270 (33%), Positives = 139/270 (51%), Gaps = 8/270 (2%)

Query: 14  IDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH 73
           ++ +++      P V  + G+GLG + + I +   + +  +P  P +TV  HAG+ VLG 
Sbjct: 14  VEFVQSKMT-IRPTVGIVCGTGLGGINEVINDKEIVKFSDIPNLPQTTVTSHAGQFVLGR 72

Query: 74  L-QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
           L  G  V+  +GR HFYEG   +I+   IR  KL+G E L  TNAAG L      G ++ 
Sbjct: 73  LPCGKEVMVQQGRYHFYEGHDQSIIVAPIRMMKLMGVETLILTNAAGGLNQSYSIGDIMV 132

Query: 133 LKDHIN---TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP-LTEGVF 188
           +KDHI        +P+VG ND RFGERF  + N YD E R  + K A++ G   +  G++
Sbjct: 133 IKDHIYFPGFAGNSPLVGPNDKRFGERFPPIYNLYDRELRKKMLKCAEQLGMDFVRHGIY 192

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK 248
            S  GP++ET  ++R +   G D VGMS   E I   H  LKVVA+S ++N      +V+
Sbjct: 193 ASVAGPHYETIFDMRFLLKNGCDAVGMSTSGEAICGAHIGLKVVAMSGVSNKFVDSEEVE 252

Query: 249 --LSHAQTLAAAELSKQNFINLICGFLRKI 276
             +   +              L+  F+ ++
Sbjct: 253 NFVDGDEVTQVVNNGVSYVSKLLERFISEL 282


>UniRef50_O57865 Uncharacterized protein PH0125 n=36 Tax=Archaea RepID=Y125_PYRHO
          Length = 257

 Score =  253 bits (647), Expect = 5e-66,   Method: Composition-based stats.
 Identities = 65/253 (25%), Positives = 110/253 (43%), Gaps = 16/253 (6%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P++  I GSG+  + +  E     +    P  P+           +G ++GV V  +   
Sbjct: 2   PKIGIIGGSGVYGVFEPKEVVKVHTPYGRPSAPIE----------IGEIEGVEVAFIPRH 51

Query: 86  GHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           G ++E     +   A I     LG E +   NA GSL+ E   G +V +   I+      
Sbjct: 52  GKYHEFPPHQVPYRANIWALHELGVERVIAINAVGSLKEEYKPGDIVIIDQFIDFTKKRE 111

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIR 203
               N  +      S+A+ +  E R +  + AKE   P+ E G +V   GP F T AE R
Sbjct: 112 YTFYNGPKVA--HVSMADPFCPELRKIFIETAKELNLPVHERGTYVCIEGPRFSTRAESR 169

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
           M +    DV+GM++VPEV  AR   +  V +S +T+     ++  +   + L   + +++
Sbjct: 170 MFRQF-ADVIGMTLVPEVNLARELGMCYVNISTVTDYDVW-AEKPVDAQEVLRVMKENEE 227

Query: 264 NFINLICGFLRKI 276
               L+   + KI
Sbjct: 228 KVQKLLKRAIPKI 240


>UniRef50_P46862 Purine nucleoside phosphorylase n=79 Tax=Actinomycetales
           RepID=PUNA_MYCLE
          Length = 268

 Score =  252 bits (644), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 92/264 (34%), Positives = 139/264 (52%), Gaps = 12/264 (4%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAI-SYEKLPGFPVSTVHGHAGELVL 71
              +I          VA +LGSG  +    + ++ A+    +LPGF      GH GEL+ 
Sbjct: 15  AAQVIGERTGILKHDVAVVLGSGWSSAVAALGSSRAVFPQAELPGFITPNAAGHTGELLS 74

Query: 72  GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
             +    V+ + GR H YEG  +  +   +RT    G  ++  TNAAG LR ++  G LV
Sbjct: 75  VRIGAHRVLVLAGRIHPYEGHDLRHVVHPVRTACAAGARIIVLTNAAGGLRADMAVGQLV 134

Query: 132 ALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSY 191
            + DH+N    +P+VG +       F  L NAY    R L    A +    LTEGV+ + 
Sbjct: 135 LISDHLNLTTRSPLVGTH-------FVDLTNAYTTRLRKL----ASDTDPTLTEGVYAAQ 183

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH 251
           PGP++ET AEIRM++++G D+VGMS V E I+AR    +V+ VS +TN+A G++   L+H
Sbjct: 184 PGPHYETPAEIRMLRMLGADLVGMSTVHETIAARAAGAEVLGVSLVTNLAAGITGKPLNH 243

Query: 252 AQTLAAAELSKQNFINLICGFLRK 275
           A+ LAA   S     +L+   + +
Sbjct: 244 AEVLAAGTASANRIGSLLADIIAR 267


>UniRef50_Q2CJ93 Purine nucleoside phosphorylase n=1 Tax=Oceanicola granulosus
           HTCC2516 RepID=Q2CJ93_9RHOB
          Length = 276

 Score =  249 bits (636), Expect = 7e-65,   Method: Composition-based stats.
 Identities = 97/269 (36%), Positives = 144/269 (53%), Gaps = 11/269 (4%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +  I+    D  P +A  LGSGLG LAD + +   I Y  +P FPVSTV GH G L++G
Sbjct: 9   AVAAIRAR-TDMVPEIALTLGSGLGPLADHL-DGTTIPYADIPHFPVSTVQGHDGVLMVG 66

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L G   V M+GR H YEG     +   +R    LG +    TNAAG +   +  G LVA
Sbjct: 67  TLFGRACVAMRGRVHMYEGYSAQEVAFPMRVMAALGAQTAIFTNAAGGMGEGMQVGDLVA 126

Query: 133 LKDHINTMPGT---PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFV 189
           ++DH++    +   P+ G ND   GERF S+  AYD E   L+Q         +  GV+ 
Sbjct: 127 IEDHLSLAVASGHDPLRGPNDPGIGERFVSMNRAYDPELIDLVQS----LSPDIARGVYG 182

Query: 190 SYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS--DV 247
              GP+FE  A IR++++ G D+ GMS VPEVI+ARH  ++V+A+SA+TN+A   +    
Sbjct: 183 HLVGPSFEPPALIRLLKLAGVDLAGMSTVPEVIAARHMGVRVLALSAVTNIAVSSTADSH 242

Query: 248 KLSHAQTLAAAELSKQNFINLICGFLRKI 276
             + A+   +  + +   + L+   +  +
Sbjct: 243 VTNEAEVWESIRIIEPKLLALMQALIPGL 271


>UniRef50_P81989 Purine nucleoside phosphorylase n=7 Tax=Actinobacteria (class)
           RepID=PUNA_CELSP
          Length = 282

 Score =  246 bits (628), Expect = 6e-64,   Method: Composition-based stats.
 Identities = 90/270 (33%), Positives = 130/270 (48%), Gaps = 17/270 (6%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQI-ENAVAISYEKLPGFPVSTVHGHAGELV 70
              D I          +A +LGSG G  A+ + E    +   ++PGF    V GH     
Sbjct: 24  AAADHIAQATGVEGHDMALVLGSGWGGAAELLGEVVAEVPTHEIPGFSAPAVAGHLSVTR 83

Query: 71  LGHLQG-----VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
              ++         + +  R H YEG+G+  +   +RT    G E L  TN  G L  E 
Sbjct: 84  SIRVERADGSVRHALVLGSRTHLYEGKGVRAVVHGVRTAAATGAETLILTNGCGGLNQEW 143

Query: 126 GAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE 185
           GAG+ V L DHIN    +P+ G         F  L + Y    R L  +V       L E
Sbjct: 144 GAGTPVLLSDHINLTARSPLEGP-------TFVDLTDVYSPRLRELAHRV----DPTLPE 192

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           GV+  +PGP++ET AE+RM  I+G D+VGMS   E I+ARHC L+V+ VS +TN+A G+S
Sbjct: 193 GVYAQFPGPHYETPAEVRMAGILGADLVGMSTTLEAIAARHCGLEVLGVSLVTNLAAGIS 252

Query: 246 DVKLSHAQTLAAAELSKQNFINLICGFLRK 275
              LSHA+ + A + +      L+    ++
Sbjct: 253 PTPLSHAEVIEAGQAAGPRISALLADIAKR 282


>UniRef50_A2FHY6 Inosine guanosine and xanthosine phosphorylase family protein n=1
           Tax=Trichomonas vaginalis RepID=A2FHY6_TRIVA
          Length = 780

 Score =  245 bits (626), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 81/265 (30%), Positives = 128/265 (48%), Gaps = 4/265 (1%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            I  +K+     TP V  +LGSGLG+   ++   + I Y+ +PG   +TV GH+G L+ G
Sbjct: 13  AIKFVKSQITG-TPEVGVVLGSGLGSYGQELAEPITIPYKNIPGMLDTTVPGHSGCLIFG 71

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            +  V V+C+ GR H YEG     +  AIR     GC L+  TNAAG+    +  G L  
Sbjct: 72  KIGEVKVLCLSGRSHQYEGLHPHEIQFAIRLLGGCGCRLVILTNAAGTCDELLEVGDLAP 131

Query: 133 LKDHINTM-PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSY 191
           + DH+N    G     L    F          YD E + ++  VA E         +   
Sbjct: 132 MLDHLNFTHRGYTEEPLEIKDFY--HLIQNGMYDKEAQQVIHDVAVESNLSTRGCNYTYN 189

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH 251
            GP +E  AE+   + +G    GMS V EVI+A+   + ++A+S +TN A G++   L+H
Sbjct: 190 MGPTYEAHAEVWGQKKLGCTNFGMSTVAEVIAAKEIGVPILAMSFVTNKAAGITGKLLTH 249

Query: 252 AQTLAAAELSKQNFINLICGFLRKI 276
            +   AA+  ++    L+   + ++
Sbjct: 250 VEVAEAAKKGEEGMKKLVSTTIMRL 274



 Score = 61.8 bits (149), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 49/236 (20%), Positives = 79/236 (33%), Gaps = 40/236 (16%)

Query: 43  IENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIR 102
           +E  V +S   LP FP   +     ++ +G L G  V  + G  + Y G         + 
Sbjct: 334 VEAKVTVSVLDLPKFPA--LQHTRAQIKIGTLAGKNVAVVDG-IYDYCGFDHYATYYLVN 390

Query: 103 TFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLAN 162
            F  LG +    T A GS   +        +KD I       +V       G    ++  
Sbjct: 391 LFAKLGAKEYIQTFATGSFGEQGVKY----IKDVIPLFERPIVVPRAMPHQGMEGTAIVA 446

Query: 163 AYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGD--VVGMSVVPE 220
            Y                            GP F T AE + M +IG     +G++V  E
Sbjct: 447 PYH---------------------------GPEFWTPAEGKAMTVIGATHATLGLTVGLE 479

Query: 221 VISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           + +A    +KVV +  I    +       +  Q + A   +      L+   L K+
Sbjct: 480 IAAA--LKMKVVGI--IDGAFDAHLLEGTTIEQIVKATTAAAPEVAKLVEESLAKV 531


>UniRef50_D1BYW2 Purine nucleotide phosphorylase n=6 Tax=Actinomycetales
           RepID=D1BYW2_XYLCX
          Length = 283

 Score =  245 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 86/269 (31%), Positives = 130/269 (48%), Gaps = 17/269 (6%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAV-AISYEKLPGFPVSTVHGHAGELV 70
              D I          +A +LGSG G  A+ + + V  I   ++PGF   TV GH G   
Sbjct: 24  AAADHIAEVSGVDGHDIALVLGSGWGGAAELLGDVVAEIPSHEIPGFAKPTVAGHVGTTR 83

Query: 71  LGHLQG-----VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
              ++        V+ +  R H YEGRG+  +  A+RT    G   L  TN  G L    
Sbjct: 84  SVCIERADGSTRNVLVLGSRTHLYEGRGVRRVAHAVRTAAATGASALVLTNGCGGLHVSW 143

Query: 126 GAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE 185
             G +V ++DH+N    +P+ G         F  + + Y    R L + V       L E
Sbjct: 144 RPGQVVLIRDHLNLTATSPLEGA-------TFVDVTDLYTPRLRELARTV----DPTLPE 192

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           GV+  +PGP++ET AE+R   I+G D+VGMS   E I+ARHC ++V+ +S +TN+A G+S
Sbjct: 193 GVYAQFPGPHYETPAEVRAAGIMGADLVGMSTGLEAIAARHCGMEVLGMSLVTNLAAGVS 252

Query: 246 DVKLSHAQTLAAAELSKQNFINLICGFLR 274
              LSH + L A   +     +L+   ++
Sbjct: 253 PQPLSHEEVLEAGAKAGPVISDLLARIVK 281


>UniRef50_Q1K0Y4 Inosine guanosine and xanthosine phosphorylase n=1
           Tax=Desulfuromonas acetoxidans DSM 684
           RepID=Q1K0Y4_DESAC
          Length = 274

 Score =  240 bits (612), Expect = 6e-62,   Method: Composition-based stats.
 Identities = 81/241 (33%), Positives = 128/241 (53%), Gaps = 7/241 (2%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLP---GFPVSTVHGHAGELVLGHLQGVPVVCMK 83
             A ILGSG  + A+ +    ++ Y ++       ++ V GHAG+L +       ++  +
Sbjct: 22  ETAIILGSGWSSWAENLVIECSLDYSEVFRTQENSIANVPGHAGKLHVATWGECRLLVFQ 81

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           GR H Y+G     ++   +    +G + L  TNA G + PE+ AGS V +KDH+N     
Sbjct: 82  GRFHLYQGLTAAQVSQTAQLAHAMGTQRLVLTNAVGGIAPELMAGSFVIIKDHLNFQGDN 141

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIR 203
           P+ GL+       F  L N Y  ++   L+  A ++G  L  GV  +  GP++ET AEIR
Sbjct: 142 PLRGLSPS----PFIDLCNLYCTDFYPDLKIWADQQGIALHRGVLAAVVGPSYETPAEIR 197

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
            ++ +G DVV MS+VPE I AR+  L+VV +S +TN A GLS   L H + L   + ++ 
Sbjct: 198 ALERLGADVVSMSMVPEAIMARYLGLEVVGLSLVTNPAAGLSTDPLQHQEVLQCGQDAQA 257

Query: 264 N 264
           +
Sbjct: 258 H 258


>UniRef50_C4FCF5 Putative uncharacterized protein n=2 Tax=Collinsella
           RepID=C4FCF5_9ACTN
          Length = 295

 Score =  238 bits (609), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 89/261 (34%), Positives = 134/261 (51%), Gaps = 9/261 (3%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS--TVHGHAGELVLGHLQGVP 78
           KP     +A +LGSGLG+L +++     I Y  + GFP     V GH+  +++G L GVP
Sbjct: 37  KPTMEHPIAIVLGSGLGSLGERVRVVRHIPYSDIDGFPTEAIPVEGHSFTVLVGELDGVP 96

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           VV   GR H Y+G     +T  +R    LGC  +  + A G++   +  G++  + D IN
Sbjct: 97  VVVYPGRVHMYQGYDALQVTSLVRHAHKLGCRSIVLSCATGAVGA-IAPGTVGIITDQIN 155

Query: 139 TMPGTPMV---GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPN 195
                P+    G+        F S+A AY      L ++ A E G  L EGV+    GP+
Sbjct: 156 LTGRNPLASPAGVAAAGLDSPFVSMAGAYSPYLSGLAREAASELGMELAEGVYAGLLGPS 215

Query: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL 255
           +ET AEIRM+  +G D VGMS V E I AR   ++V+ ++ +TN A    +   SHA+ L
Sbjct: 216 YETPAEIRMLGTLGADYVGMSTVCEAIMARAMGMEVLGIALVTNKAGCPGE---SHAKVL 272

Query: 256 AAAELSKQNFINLICGFLRKI 276
            AA+ + +    L    +R+I
Sbjct: 273 GAADAAAEAMQALALATIRRI 293


>UniRef50_Q28ZG3 GA14805 n=2 Tax=pseudoobscura subgroup RepID=Q28ZG3_DROPS
          Length = 333

 Score =  238 bits (608), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 88/254 (34%), Positives = 128/254 (50%), Gaps = 9/254 (3%)

Query: 23  DFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPV-STVHGHAGELVLGHLQGVPVVC 81
              PR+  I G  L  L D IE  V I +E +P FPV ST+ G    LV+G + G  V+ 
Sbjct: 63  QMRPRIGLICGHFLRQLVDIIEEPVLIPFEDIPQFPVCSTLEGARNHLVVGTVMGATVMA 122

Query: 82  MKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMP 141
           M+ R H YEG  +      +R  KL G + +  T AA ++ P+   G ++ +KDHIN + 
Sbjct: 123 MQDRFHTYEGYQLASSVLPVRVMKLCGVQHILLTCAAAAVNPQYAVGDIMLIKDHINMLG 182

Query: 142 ---GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNF 196
               TP+ G +D RFG R  ++  AYD        ++  E GF   L  GVF    GP  
Sbjct: 183 MFDRTPLTGAHDPRFGVRKLAMTRAYDRHLIEKSLQIGGELGFDDCLQVGVFGCLCGPTC 242

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLA 256
           +T AE  M++++G D VGMS+V EVI + HC LK+ ++  IT +A    D +   A+   
Sbjct: 243 KTNAEGEMLRVMGVDAVGMSLVHEVIVSHHCGLKIFSLGIIT-LAASKDDEQHEVAEAQE 301

Query: 257 A--AELSKQNFINL 268
               +  +     L
Sbjct: 302 TQETQEMEMPMQRL 315


>UniRef50_Q83H43 Purine nucleoside phosphorylase n=3 Tax=Tropheryma whipplei
           RepID=Q83H43_TROWT
          Length = 294

 Score =  237 bits (604), Expect = 4e-61,   Method: Composition-based stats.
 Identities = 84/267 (31%), Positives = 131/267 (49%), Gaps = 13/267 (4%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGL-GALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
                I          +A  LGSG   A+++  E    I  + + GF    + GH+G L 
Sbjct: 31  LAAKQIADITGIARHDIAVTLGSGWVDAVSNLGELITTIPAQDIHGFFPPVLAGHSGVLT 90

Query: 71  LGHL-QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGS 129
              L  GV V+ +  R H Y+G G   +   I+T    G  +   TN AGS  P+ G G 
Sbjct: 91  SIRLTCGVYVLVIGARTHLYQGHGPEAVVHGIKTAHAAGARVAILTNGAGSTVPDWGPGE 150

Query: 130 LVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFV 189
           +V +KDHIN    +P+ G N       F  +++ Y A  R  + ++A      + +GV+ 
Sbjct: 151 VVVIKDHINLTGKSPLSGAN-------FCDMSDIYTAALRQKILQMAPN----IPQGVYA 199

Query: 190 SYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKL 249
             PGP +ET AE++M++ IG D+VGMS   E I A+   + VV +S +TN+A G+   +L
Sbjct: 200 QMPGPQYETPAEVKMLRTIGADLVGMSTALEAIMAKSLKMNVVGLSLVTNLAAGIGTGQL 259

Query: 250 SHAQTLAAAELSKQNFINLICGFLRKI 276
           SH + L  +E ++Q     +   +R I
Sbjct: 260 SHDEVLTVSEQARQKTSAFLVELIRDI 286


>UniRef50_Q7URV0 Purine nucleoside phosphorylase I n=1 Tax=Rhodopirellula baltica
           RepID=Q7URV0_RHOBA
          Length = 305

 Score =  236 bits (602), Expect = 8e-61,   Method: Composition-based stats.
 Identities = 79/250 (31%), Positives = 121/250 (48%), Gaps = 17/250 (6%)

Query: 40  ADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTD 99
           AD IE+   + Y ++PG   ST  GH GE ++GHL   P++ M GR H YEG  +  +T 
Sbjct: 51  ADAIESPTIVPYAEIPGLAPSTASGHRGEFLIGHLASRPIIAMAGRLHVYEGHSLRDVTR 110

Query: 100 AIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG----------TPMVG-- 147
            +     +G   L  + AAG L P+   G LV L +H + + G           P+    
Sbjct: 111 PVALMAGIGINELVVSCAAGGLNPQFKVGDLVLLSEHSSWLDGKLGAPPISFQQPISFQQ 170

Query: 148 LND-----DRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEI 202
            ND     D   + F    N  D +  A+  + A   GF L  G++++  GPN+ET AE 
Sbjct: 171 PNDLPNESDAAAKCFRRSLNTCDPQLDAIAHQTAHANGFELRRGMYLAVNGPNYETRAEC 230

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
           RMM+ +G D+VGMS VPE++ A    ++ + +S +TN+A   +     HA  L   E + 
Sbjct: 231 RMMRQLGADLVGMSTVPELLCANSAGVRTLGISVVTNLALPDAPATADHADVLEVCERAA 290

Query: 263 QNFINLICGF 272
                ++   
Sbjct: 291 NRLQQIVRAI 300


>UniRef50_C7MEB8 Purine nucleotide phosphorylase n=2 Tax=Micrococcineae
           RepID=C7MEB8_BRAFD
          Length = 287

 Score =  235 bits (601), Expect = 9e-61,   Method: Composition-based stats.
 Identities = 79/255 (30%), Positives = 125/255 (49%), Gaps = 14/255 (5%)

Query: 26  PRVAFILGSGLGALADQI-ENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGV--PVVCM 82
             +A +LGSG    AD + E         +PGF  + V GH G L    ++G     + +
Sbjct: 28  HDLALVLGSGWSGAADLLGETVWQADATTIPGFRPAAVAGHVGTLRSIRVEGTGARALVL 87

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
             R HFYEG G+  +   +RT    G   +  TN  G + P    G+ V ++D IN    
Sbjct: 88  GARTHFYEGAGVDAVVHGVRTAAATGARTMVLTNGCGGIDPAWAPGTPVLIRDQINFTGA 147

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEI 202
           TP+VG N       F  L + Y    R    ++A++    L EGV++ + GP++ET AE+
Sbjct: 148 TPLVGAN-------FVDLTDLYTPALR----EIARDVDATLDEGVYMQFSGPSYETPAEV 196

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
           +M + +G  +VGMS   E I+ R   + ++ +S +TN+A G+S   LSH + L A   + 
Sbjct: 197 QMAKAMGAHLVGMSTALEAIAVREAGMDLLGISLVTNLAAGISGDALSHEEVLEAGRAAG 256

Query: 263 QNFINLICGFLRKIA 277
                L+   +R+I 
Sbjct: 257 PRISRLLAETVRRIT 271


>UniRef50_Q0W2D2 Putative purine phosphorylase (Family 2) n=1 Tax=uncultured
           methanogenic archaeon RC-I RepID=Q0W2D2_UNCMA
          Length = 258

 Score =  235 bits (599), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 66/254 (25%), Positives = 107/254 (42%), Gaps = 16/254 (6%)

Query: 26  PRVAFILGSGLGALAD-QIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           PR A I GSG   +    ++    +           T +G A      + +G   V +  
Sbjct: 2   PRTAIIGGSGFYCVPGCNLKEKKVV----------RTKYGDATLFFYENEKGAEFVFLPR 51

Query: 85  RG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            G  H      +    + I   K  G E +   ++ GSLR  +  G  V L   ++    
Sbjct: 52  HGEGHTCAPHRINYRANVI-ALKEAGIERIIGISSVGSLREAIRPGDFVLLDQFLDFTKA 110

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEI 202
            P+   ++D        +   Y  + R  +    + +     +G +V   GP FETAAEI
Sbjct: 111 RPITFFDEDGC-VVHTDMTEPYCHDLRQCILSAPRGDIRLHDKGTYVCTEGPRFETAAEI 169

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
           RM   +GGDVVGM+ VPEV+ AR   +    +S  TN A G+S V ++H + L A +  +
Sbjct: 170 RMYATLGGDVVGMTGVPEVVLARELGMCYAGISVATNYAAGISKV-VTHEEVLEAMKKIE 228

Query: 263 QNFINLICGFLRKI 276
               + + G +  +
Sbjct: 229 TVLASYVVGCITTV 242


>UniRef50_C5C9E7 Purine nucleotide phosphorylase n=3 Tax=Actinomycetales
           RepID=C5C9E7_MICLC
          Length = 301

 Score =  234 bits (597), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 88/267 (32%), Positives = 130/267 (48%), Gaps = 13/267 (4%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVA-ISYEKLPGFPVSTVHGHAGELV 70
              D I         R+A +LGSG G  A  I + VA +   ++PGF    V GH   + 
Sbjct: 46  AAADTIARATGVAEHRIAVVLGSGWGEAAGLIGDEVAAVPLAEVPGFHAPKVPGHNAVIR 105

Query: 71  LGHL-QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGS 129
              L  G   +    R HFYE R    +   +RT    G   +  TN  G + PE+  G+
Sbjct: 106 SVRLPDGTHTLVFGSRTHFYESRDAQAVAHTVRTAAAAGARTVVLTNGCGGMDPEIAPGT 165

Query: 130 LVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFV 189
            V + DHIN    TP+        G  F  L + Y    RA    +A+E    L EGV+V
Sbjct: 166 PVLIADHINLTGATPL-------AGATFVDLTDLYSPRLRA----IAREVDPSLREGVYV 214

Query: 190 SYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKL 249
            + GP +ET AE+RM + +GGD+VGMS   + I+ARH  L+V  +S +TN+  G+S+  L
Sbjct: 215 QFAGPQYETPAEVRMARTLGGDLVGMSTALDAIAARHAGLEVFGISLVTNLGAGISETPL 274

Query: 250 SHAQTLAAAELSKQNFINLICGFLRKI 276
           SHA+ + A + +      L+   + ++
Sbjct: 275 SHAEVVEAGQAAGPRIARLLADIVGRL 301


>UniRef50_B9CNR2 Purine nucleoside phosphorylase 1 n=2 Tax=Atopobium
           RepID=B9CNR2_9ACTN
          Length = 396

 Score =  232 bits (591), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 85/268 (31%), Positives = 125/268 (46%), Gaps = 7/268 (2%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS--TVHGHAGEL 69
                ++  KP     VA +LG+GLG LA+ ++    I Y  + GFPV    V GH+ E 
Sbjct: 133 VTEKTVEEIKPSVEHPVALVLGTGLGHLANLVKPVRRIDYRDIEGFPVDAQPVTGHSFEA 192

Query: 70  VLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGS 129
            +G + GVPVV   GR H Y+G     +T  ++    LGC  +    A G++    G G 
Sbjct: 193 TIGTIDGVPVVVYPGRVHLYQGYSAAEVTALVQHAHHLGCRDIIFAGATGAVPGNAGTG- 251

Query: 130 LVALKDHINTMPGTPMV-GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVF 188
           L  + D IN     P+            F  + +AY    R L + VA + G  + EG+F
Sbjct: 252 LGIITDQINLTGTNPLAEWAGLKNVETPFVDMNDAYSPYLRTLARGVADDLGITVEEGIF 311

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK 248
               GPNFET AE+ M++ +     G+S   EVI AR  ++ V+ ++   N A       
Sbjct: 312 AGLLGPNFETPAEVNMLRAMNVSYTGVSTALEVIMARALNMNVLGLTLAANPAGARG--- 368

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKI 276
            +H   L AAE    +F  L+ G LR +
Sbjct: 369 TTHKSVLEAAEHYADDFERLVRGILRLL 396


>UniRef50_D2VAE0 Purine phosphorylase family protein n=1 Tax=Naegleria gruberi
           RepID=D2VAE0_NAEGR
          Length = 840

 Score =  230 bits (587), Expect = 4e-59,   Method: Composition-based stats.
 Identities = 82/278 (29%), Positives = 133/278 (47%), Gaps = 32/278 (11%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL-----QGVPVVCM 82
           +A +LGSGLG     + NA  +SY ++P  P ++V GH+GEL+LG L     Q   + C 
Sbjct: 24  MAIVLGSGLGDFPKVLLNAKKLSYSQIPHMPQTSVQGHSGELILGELPTNDNQKRLIYCF 83

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            GR H YEG     +T  ++    +GC+L   TNA+G L  E+  G L  L  H   +  
Sbjct: 84  AGRIHSYEGGPWDEVTFQVKLMASIGCKLFIMTNASGGLFDEMSGGCLCLLTGHFRLLAR 143

Query: 143 ------------------------TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE 178
                                      +   +D++          + ++Y  L + VAKE
Sbjct: 144 MDPNSLAPGARVSNGQLLETSFEKNEQISQIEDKYSHFAPDY---WTSKYVNLCRSVAKE 200

Query: 179 EGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
           +G  L EG +    GP+FET  E+ M + +GG  VGMS VPE+++  +  ++ + +S + 
Sbjct: 201 QGIKLFEGSYAWASGPSFETPLEVLMAKQLGGACVGMSTVPEMLTCNYYGMECMGISMVC 260

Query: 239 NMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           N+  GL    L+H + L  +++  ++   L+   L KI
Sbjct: 261 NLGAGLQTEPLTHKEVLENSKIGTEHMQLLVKETLSKI 298



 Score = 62.6 bits (151), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 28/137 (20%), Positives = 57/137 (41%), Gaps = 15/137 (10%)

Query: 41  DQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG-----RGHFYEGRGMT 95
           + I+   ++ ++ +P     T  G    L L  +    ++ +          +     + 
Sbjct: 612 ENIKIIKSVPFKNIPHL--QTEFG--QTLSLATIGDKHILVVHHIDQSDESTYLRSNSLI 667

Query: 96  IMTDAIRTFKLL-GCELLFCTNAAGS-LR----PEVGAGSLVALKDHINTMPGTPMVGLN 149
            ++  IR  + L     ++  +A  S L     P     +LV  +DHIN     P++G N
Sbjct: 668 ELSFIIRVCQHLHTVNNIYLNSAVVSALNSNFEPIYTPNTLVQYRDHINFTGYNPLIGKN 727

Query: 150 DDRFGERFFSLANAYDA 166
           ++R+G+RFF ++  Y  
Sbjct: 728 ENRWGDRFFDVSGLYRP 744


>UniRef50_Q13126 S-methyl-5'-thioadenosine phosphorylase n=55 Tax=cellular organisms
           RepID=MTAP_HUMAN
          Length = 283

 Score =  224 bits (572), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 59/257 (22%), Positives = 106/257 (41%), Gaps = 16/257 (6%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM--KG 84
           ++  I G+GL    + +E       +   G P       +  L+LG ++ V  V +   G
Sbjct: 11  KIGIIGGTGLDD-PEILEGRTEKYVDTPFGKP-------SDALILGKIKNVDCVLLARHG 62

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H      +    + I   K  GC  +  T A GSLR E+  G +V +   I+     P
Sbjct: 63  RQHTIMPSKVNYQAN-IWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRP 121

Query: 145 MVGLNDDR---FGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAA 200
               +       G     +A  +  + R +L + AK+ G     +G  V+  GP F + A
Sbjct: 122 QSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRA 181

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS-DVKLSHAQTLAAAE 259
           E  M +  G DV+ M+ VPEV+ A+   +   +++  T+       +  +S  + L   +
Sbjct: 182 ESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLK 241

Query: 260 LSKQNFINLICGFLRKI 276
            +     +L+   + +I
Sbjct: 242 ENANKAKSLLLTTIPQI 258


>UniRef50_A8B9X8 Purine nucleoside phosphorylase lateral transfer candidate n=3
           Tax=Giardia intestinalis RepID=A8B9X8_GIALA
          Length = 805

 Score =  224 bits (572), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 81/315 (25%), Positives = 136/315 (43%), Gaps = 45/315 (14%)

Query: 6   FSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQI--ENAVAISYEKLPGFPVSTVH 63
           F+ +     D IK         +A +LGSGL   AD++       I YE++P    ++V 
Sbjct: 28  FTSHMHEAADYIKNIIGKKV-DIAVVLGSGLSGFADRMFSTGYTEIDYERVPFMAKTSVS 86

Query: 64  GHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRP 123
           GH+G++++G +    ++C  GR H YEG     +T        LG  +   TNAAG  + 
Sbjct: 87  GHSGKVLVGEMGDKTILCFSGRFHSYEGYTPPTLTIFPYVACYLGARIYIVTNAAGGTKR 146

Query: 124 EVGAGSLVALKDHINTMPGTPMVGLNDDRFGERF-------------------------- 157
            + AG L+ + D ++ +   P+ G    +                               
Sbjct: 147 GMEAGCLMLINDQMSLLRWNPLYGYESCQLQHDPDCLLELENLKALLGYLKTPGLFHYPS 206

Query: 158 -FSLANAYDAEYRALLQKVAKEEGF---------------PLTEGVFVSYPGPNFETAAE 201
               AN Y AE R+L++++AK++ F                + EG +V   GP++ET  +
Sbjct: 207 SIPNANIYSAELRSLVRELAKDKAFIDKTSIMLKGHKHMVKVYEGTYVLNSGPHYETQID 266

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELS 261
              +  +G   VGMS +PE + AR   + V+ +S +TN+A GLS   L HA     ++  
Sbjct: 267 TETIMSLGPGAVGMSSIPEALCARLLGMHVIGLSVVTNLAAGLSKETLDHADVKLVSDAV 326

Query: 262 KQNFINLICGFLRKI 276
                 LI   + ++
Sbjct: 327 STAVYALIGALIARV 341



 Score = 46.4 bits (109), Expect = 0.001,   Method: Composition-based stats.
 Identities = 15/76 (19%), Positives = 28/76 (36%), Gaps = 6/76 (7%)

Query: 93  GMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDR 152
            +   T   R  ++LG + +        +  +V    +    D  N      + G NDDR
Sbjct: 656 SLQETTFPARLCQVLGVQRVIL------ITDQVQTKDIYCATDVYNVSCVNALRGHNDDR 709

Query: 153 FGERFFSLANAYDAEY 168
           +G RF  ++   +   
Sbjct: 710 WGARFIDVSGICNKGL 725


>UniRef50_C0QPX3 Methylthioadenosine phosphorylase n=6 Tax=Aquificales
           RepID=C0QPX3_PERMH
          Length = 280

 Score =  224 bits (571), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 59/271 (21%), Positives = 113/271 (41%), Gaps = 31/271 (11%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +  I GSGL  + D I     ++     G P       +   ++   +G   V +   G 
Sbjct: 2   LGVIGGSGLYQV-DDINILDEVNISTPYGEP-------SDRYIIAEYRGKKAVFLPRHGK 53

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H Y    +    + I  F+ LG + +   +A G + P +  G  V     I+     P+
Sbjct: 54  GHKYPPHLINYRAN-IWGFRKLGVDRILSVSAVGGINPLLKPGDFVLSDQFIDFTKVRPV 112

Query: 146 VGLN------DDRFG-------------ERFFSLANAYDAEYRALLQKVAKEEGFPLTE- 185
                     D+  G                  + + + +  R  L  +  E+G+   + 
Sbjct: 113 TFYEGVYTIYDETDGKDDLVSEYLKNNRVVHIDVTDPFCSSMRKTLSDILDEKGYRYHKK 172

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           G +++  GP  ET+AEI+   I+G D+VGM++VPE++ AR   +   +++ +TN+A G+S
Sbjct: 173 GTYIATEGPRLETSAEIKAFSILGADIVGMTLVPEIVLARELSMHFASINVVTNLAAGIS 232

Query: 246 DVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
             +L+  + +   +        +I  F+ K+
Sbjct: 233 GERLTSDEVIQMMKEKNDQIKEIILSFIEKV 263


>UniRef50_O27633 Methylthioadenosine phosphorylase n=7 Tax=Archaea
           RepID=O27633_METTH
          Length = 280

 Score =  223 bits (569), Expect = 4e-57,   Method: Composition-based stats.
 Identities = 59/218 (27%), Positives = 95/218 (43%), Gaps = 10/218 (4%)

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGR--GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAA 118
           T +G   E+ +  L G  V  +     GH      +    + I   K LG   +  TNA 
Sbjct: 27  TPYGKTPEISVFKLHGRRVAFIPRHSPGHDKPPHMVNYRAN-IWALKELGVRQIIATNAV 85

Query: 119 GSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE 178
           GSL+  +G G  V   D ++     P    ++         +   Y    R+ L      
Sbjct: 86  GSLKRSIGPGDFVVPHDFLDFTRSRPSTFYDEKTV---HVDMTEPYCRNIRSAL----SG 138

Query: 179 EGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
               +  GV+V   GP FET AEIRM Q +GG VVGM+ +PE + AR  ++   ++  ++
Sbjct: 139 SSGVVDGGVYVCTEGPRFETPAEIRMFQTLGGTVVGMTGLPEAVLARELEMCYASICLVS 198

Query: 239 NMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           N A  +S  KL+  +     +  K + I++I   +R +
Sbjct: 199 NYAASISPSKLTIDEVFEIMDEKKNDLIDIIDAAIRDL 236


>UniRef50_B3T2V4 Putative phosphorylase family 2 n=2 Tax=environmental samples
           RepID=B3T2V4_9ARCH
          Length = 268

 Score =  222 bits (567), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 54/255 (21%), Positives = 107/255 (41%), Gaps = 15/255 (5%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           T  +    G+G+   ++ ++++  I+ E   G    T+        +G  +G  +  M  
Sbjct: 5   TAEIGIFGGTGIYD-SELLQDSKEITIETPYGKTSDTIT-------IGEFKGKKIAFMPR 56

Query: 85  RG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            G  H      +    + +  FK LG   +   +A GSL+ E+  G+ V     I+    
Sbjct: 57  HGKKHSIPPHMINYCAN-VWAFKELGITRIVSPSAVGSLKEEIKPGNFVLPTQFIDFTKS 115

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAE 201
                  D R      S+A+ +  E + ++ + A  +G  L +   +    GP F T AE
Sbjct: 116 RKNSFSEDGR--VIHISVADPFCPELQEIVSETANNQGITLHKDCTYACIEGPRFSTKAE 173

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELS 261
            R  +  G D++GM++VPE   AR   +  V++S +T+     ++  ++  + +     +
Sbjct: 174 SRFYKSTGSDIIGMTLVPECQLAREAQICYVSISTVTDYDVW-AEKPVTAKEVMDTLSKN 232

Query: 262 KQNFINLICGFLRKI 276
            Q    L+   + K+
Sbjct: 233 VQTTKKLLAELIHKM 247


>UniRef50_B0K2V3 Purine phosphorylase, family 2 n=10 Tax=Thermoanaerobacteraceae
           RepID=B0K2V3_THEPX
          Length = 256

 Score =  222 bits (567), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 68/250 (27%), Positives = 111/250 (44%), Gaps = 16/250 (6%)

Query: 29  AFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHF 88
           A I G+G   +  ++   +           V T +G   E+ +  ++G  +  +   G  
Sbjct: 4   AIIGGTGFYEIGQKVSKKL-----------VETKYGEV-EIDIVTIEGEKIGFLPRHGKG 51

Query: 89  YEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG 147
           +      +   A I   K +G + ++ T A GS       G +V LKD ++     P+  
Sbjct: 52  HAVPPHLVNYRANIMALKQMGVKYVYATAAVGSFNENYEPGDVVVLKDFLDFTKSRPLTF 111

Query: 148 LNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIRMMQ 206
              +    R   +++ Y +  RA     AK+E   +  + V+V   GP FETA EIRM +
Sbjct: 112 FEGEDGVVRHVDMSDPYCSNLRAKFYNAAKKEDLLIKGDAVYVCTEGPRFETAQEIRMYK 171

Query: 207 IIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFI 266
            +G DVVGM+ VPEVI A+   +   AV  ++N A G+      H +     EL+K+  I
Sbjct: 172 NLGADVVGMTNVPEVILAKELGMCYAAVGIVSNWATGMKGSITLH-EIKDTLELNKEKVI 230

Query: 267 N-LICGFLRK 275
              I  FL +
Sbjct: 231 KTFIRVFLEE 240


>UniRef50_B1I2E1 Methylthioadenosine phosphorylase n=33 Tax=cellular organisms
           RepID=B1I2E1_DESAP
          Length = 292

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 68/256 (26%), Positives = 109/256 (42%), Gaps = 20/256 (7%)

Query: 24  FTPRVAFILGSGLGA---LADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
            T R+A I G+G+     L +  E+ V   Y ++             +L +G  +G  V 
Sbjct: 1   MTVRIAVIGGTGVYDPAMLGEIREDHVRTPYGEV-------------DLQVGRFEGREVA 47

Query: 81  CMKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
            M   G  H      +    + I   K LG   +  T A GSL  ++  G  V     ++
Sbjct: 48  FMARHGRWHSVPPHLVNYRAN-IMALKQLGVRSILATAAVGSLNLDMKPGDFVFCDQFLD 106

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFE 197
                          G     +   Y  E RALL++ A      +  G  + +  GP FE
Sbjct: 107 FTKSRAQTFFEGGPEGVVHVDMTEPYCPELRALLEEAAAALKLTVHPGGTYAATEGPRFE 166

Query: 198 TAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAA 257
           + AEIRM++ +G D+ GM+ VPEV+ AR   +    +  +TN A G+S  +L+H + L A
Sbjct: 167 SPAEIRMLRHLGADLAGMTGVPEVVLAREAGICYATICMVTNFAAGISPHRLTHEEVLEA 226

Query: 258 AELSKQNFINLICGFL 273
             ++     +LI G +
Sbjct: 227 MRVNAAKIRSLIAGTV 242


>UniRef50_A3DD28 Methylthioadenosine phosphorylase n=7 Tax=Clostridia
           RepID=A3DD28_CLOTH
          Length = 268

 Score =  221 bits (563), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 56/261 (21%), Positives = 102/261 (39%), Gaps = 20/261 (7%)

Query: 23  DFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM 82
           ++   +    GSG  +    +EN   I  E   G P       + ++ +   +G  +  +
Sbjct: 2   NYKADIGVFGGSGFYSF---LENVEEIEMETPYGKP-------SDKIAIATYEGKRIAFL 51

Query: 83  KGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
              G  H +    +    + +   K LG + +    ++GSLR ++  G  V     ++  
Sbjct: 52  PRHGKNHQFPPHMIPYRAN-LYAMKKLGVKKILAPTSSGSLRADIKPGDFVICDQFVDRT 110

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETA 199
            G      +      +  S A+ Y  E R +  +V K+ G    E G  V   GP F T 
Sbjct: 111 TGRKDTFYDGP--VTKHISSAHPYCPELRKIAIQVGKDLGITTHEKGTVVVIQGPRFSTV 168

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD----VKLSHAQTL 255
           AE R    +G DV+ M+  PEV  AR   +    ++ IT+   GL        ++    L
Sbjct: 169 AESRWFSKMGWDVINMTQYPEVYLARELGICYANIALITDYDAGLEGRDDIEPVTEEAVL 228

Query: 256 AAAELSKQNFINLICGFLRKI 276
                + +   N++   +++I
Sbjct: 229 KVFAENNEKVKNMLFEVIKRI 249


>UniRef50_Q9W1K6 CG18128 n=7 Tax=melanogaster group RepID=Q9W1K6_DROME
          Length = 339

 Score =  221 bits (563), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 77/246 (31%), Positives = 114/246 (46%), Gaps = 7/246 (2%)

Query: 24  FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
             P+   I GS L  +   +E  V I YE +P FP       +   VLG + G P++ + 
Sbjct: 63  IRPKYGLICGSFLSDMVSLVEQPVVIPYEDIPNFPDGIEPDCS--FVLGTVMGAPIIALV 120

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN---TM 140
              H  +G  +      +R  +L G   +  T+ A ++      G ++ ++DHIN    M
Sbjct: 121 HSFHSCDGYNLATCALPVRVMQLCGVRTIMLTSEAAAVDHGFALGDIMLVQDHINVVGMM 180

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNFET 198
             TP+ G +D RFG R FS+ NAYD +      ++ K  G    L  GV     GP   T
Sbjct: 181 HQTPLEGPSDPRFGSRRFSMVNAYDKDLLEKALEIGKRMGIQKFLHSGVLACMGGPILGT 240

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
            AE RM++ +    VGMS+VPEVI+A H  LKV+A   I+  A      +    +     
Sbjct: 241 VAEERMLRTMEVSAVGMSLVPEVIAAHHGGLKVLAFVVISRAASDKESEESDKDKEKDTD 300

Query: 259 ELSKQN 264
             SKQ+
Sbjct: 301 RDSKQD 306


>UniRef50_A9A3N5 Methylthioadenosine phosphorylase n=4 Tax=Archaea
           RepID=A9A3N5_NITMS
          Length = 263

 Score =  220 bits (562), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 50/253 (19%), Positives = 102/253 (40%), Gaps = 15/253 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
            +    G+G+   +  +E+A  +  +   G P  T+        +G  +G  +  +   G
Sbjct: 6   EIGIFGGTGIYD-SGLLEDAKEVDIDTPYGKPSDTIT-------VGTFKGRKIAFLPRHG 57

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + I  FK LG   +   +A GSL+ E+  G  V     ++      
Sbjct: 58  KKHTIPPHMINFKAN-IWAFKELGVTRIIAPSAVGSLKEELAPGHFVLPTQFLDFTKSRD 116

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIR 203
                D R      S+A+ +  E ++ + +V       + +   +V   GP F T AE +
Sbjct: 117 GSFSEDGR--VIHISVADPFCPELQSSITEVTDSLDMNIHKDCTYVCIEGPRFSTKAESK 174

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
             +  G D++GM++VPE   AR   +   ++S +T+     ++  ++  + L     + +
Sbjct: 175 FYRTTGADIIGMTLVPECQLAREAQICYASISTVTDYDVW-AEKPVTAKEVLETLSKNVE 233

Query: 264 NFINLICGFLRKI 276
               ++   + KI
Sbjct: 234 GTKKILTELIEKI 246


>UniRef50_B9KXK8 Purine nucleoside phosphorylase n=2 Tax=Thermomicrobia (class)
           RepID=B9KXK8_THERP
          Length = 289

 Score =  220 bits (560), Expect = 5e-56,   Method: Composition-based stats.
 Identities = 92/262 (35%), Positives = 126/262 (48%), Gaps = 2/262 (0%)

Query: 17  IKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQG 76
           I   +   TP    +LGSGL  L +       +  ++L       V GH  ELVL    G
Sbjct: 17  ILAQRYHHTPDALIVLGSGLATLPEDAHVVARVPLDELTAIAAPAVTGHPRELVLAEWNG 76

Query: 77  VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDH 136
            P+    GR H Y+G         I     L   ++  TNAAGSL P    G LV ++DH
Sbjct: 77  HPIWFCLGRYHLYQGLSAAEAAAPIALLAHLPGPIVILTNAAGSLHPTFAPGDLVLIRDH 136

Query: 137 INTMPGTPMVGLNDDRFG-ERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPN 195
              +PG           G  RFFSL +AYD   RA+ +  A   G  L EG +    GP 
Sbjct: 137 F-FVPGLAGHHPLIPPAGRVRFFSLRDAYDRHLRAVARAAAARLGLELPEGTYAMVAGPT 195

Query: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL 255
           FETAAE+R ++  G D+VGMS +PEVI AR   L+V+A+S +TN+A        +H +  
Sbjct: 196 FETAAELRWLRAAGADLVGMSTIPEVILARALGLRVLAISVVTNLAIPEEPAIPTHEEVA 255

Query: 256 AAAELSKQNFINLICGFLRKIA 277
           A  E ++     L+  FL ++A
Sbjct: 256 AIGEQARPRLHRLLGFFLDQLA 277


>UniRef50_Q7ZV22 Methylthioadenosine phosphorylase n=20 Tax=Metazoa
           RepID=Q7ZV22_DANRE
          Length = 280

 Score =  218 bits (555), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 59/256 (23%), Positives = 102/256 (39%), Gaps = 14/256 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I GSGL    D +E           G P       +  L+LG ++ V  V +   G
Sbjct: 8   KIGIIGGSGLDD-PDILEGRTERYVVTPYGKP-------SDALILGKIKNVDCVLLARHG 59

Query: 87  HFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
             +      +   A I   K  GC  L  T A GSLR ++  G +V +   I+       
Sbjct: 60  RQHTIMPTNVNYQANIWALKEEGCTHLLVTTACGSLREDIQPGDIVLIDQFIDRTTKRVQ 119

Query: 146 VGLNDDRF---GERFFSLANAYDAEYRALLQKVAKEEGFP-LTEGVFVSYPGPNFETAAE 201
              +       G     +A  + ++ R +L +VA+  G    T G  V+  GP F + AE
Sbjct: 120 TFYDGQPTSPPGVCHIPMAEPFCSKTREVLLEVAQGLGVKCHTRGTMVTIEGPRFSSRAE 179

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS-DVKLSHAQTLAAAEL 260
             M +  G DV+ M+ VPEV+ A+   L   +++  T+       +  +     L   + 
Sbjct: 180 SLMFRQWGADVINMTTVPEVVLAKEAGLCYASIAMATDYDCWKEHEEAVCVDNVLKTMKE 239

Query: 261 SKQNFINLICGFLRKI 276
           +     +++   + +I
Sbjct: 240 NANKASSILLTAIPQI 255


>UniRef50_B5Y8G4 Methylthioadenosine phosphorylase n=1 Tax=Coprothermobacter
           proteolyticus DSM 5265 RepID=B5Y8G4_COPPD
          Length = 249

 Score =  215 bits (548), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 64/253 (25%), Positives = 115/253 (45%), Gaps = 20/253 (7%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I GSG+  +         +   ++    V+T +G   ++ L  +    V  +   G
Sbjct: 2   KIGVIGGSGIYQIEG-------VPSTEI---SVNTEYGEV-KVFLAQVDDREVYFLPRHG 50

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + IR  + LG + +  TNA GSL PE+  G++V +   ++   G  
Sbjct: 51  LGHSVPPHLVNYRAN-IRALQGLGAQRIIATNAVGSLNPEIKPGTVVLVDQFLDFTKGRK 109

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIR 203
                + +       + N Y  E   +  K+     FPL +G V V   GP FETAAE++
Sbjct: 110 STFFEEGK--VVHTDMTNPYCPEMIEVASKIT--TPFPLRKGGVMVVTEGPRFETAAEVK 165

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
              ++GGDVVGM+ VPEV+ +R   +  ++++ ++N A GL +  +SH + L   +    
Sbjct: 166 AFAMLGGDVVGMTSVPEVVLSREAGMCYLSLAIVSNFAAGLQEQ-VSHEEVLNIMDKLNN 224

Query: 264 NFINLICGFLRKI 276
                I   ++ +
Sbjct: 225 QVQMFILDLIKAM 237


>UniRef50_UPI000038E4F5 5''''-methylthioadenosine phosphorylase II n=1 Tax=Ferroplasma
           acidarmanus fer1 RepID=UPI000038E4F5
          Length = 257

 Score =  214 bits (546), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 52/251 (20%), Positives = 104/251 (41%), Gaps = 16/251 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           V  I GSGL ++   +E    +  +   G P + +        +G + GV V  +   G 
Sbjct: 4   VGIIGGSGLYSI---METRKTMDIDTPYGKPSAPLE-------IGEINGVEVAFLPRHGK 53

Query: 88  FYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
            +      +   A I   +  G + +   NA GSL+ E   G +V     I+      + 
Sbjct: 54  KHTIPPHMVNYKANIFALQKAGVQRIIGLNAVGSLKEEYKPGDIVIPDQFIDFTKRRDLT 113

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRMM 205
             N         S+A+ + ++  A   +  K+  FP+ + G ++   GP F T AE +M 
Sbjct: 114 YYNGPDVY--HISMADPFCSDISAKAYEAGKKLSFPVHKNGAYICIEGPRFSTRAESKMF 171

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNF 265
           +    D++GM++VPE+  A    +    ++ +T+      D  +  +  +   + S++  
Sbjct: 172 RNF-ADIIGMTLVPEINLAAELSMCYGMLATVTDYDAW-KDEAVEASDVMQIMKESEEKV 229

Query: 266 INLICGFLRKI 276
             ++   + +I
Sbjct: 230 SKMLYNLVPEI 240


>UniRef50_B3RV47 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
           RepID=B3RV47_TRIAD
          Length = 294

 Score =  213 bits (542), Expect = 6e-54,   Method: Composition-based stats.
 Identities = 78/278 (28%), Positives = 135/278 (48%), Gaps = 14/278 (5%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAG-ELV 70
              + ++  K   +P++  + G GL A+A+ I+    IS   LP FP       +  +L+
Sbjct: 16  TIANYLRK-KTRLSPKIGLVCGKGLDAVANIIQKKQVISCSSLPCFPSPNYKATSDHDLI 74

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
            G + G PV+C++G+ H YEG  +  +   I+    LG E+L     + SL P+   G +
Sbjct: 75  FGLVSGKPVICIQGQYHMYEGFSIETVILPIKIMFALGVEILLTIGVSRSLNPDFDIGDI 134

Query: 131 VALKDHINT--MPGTPMVGLNDDRFGER----FFSLANAYDAEYRALLQKVAKEEGFP-- 182
           V +KDHIN   + GT        +   +        +NAYD   R++++  A+  G    
Sbjct: 135 VLVKDHINLPSLCGTDSACYGTTKQTRQLNGTPIVKSNAYDVRLRSVVESSARTCGIGEL 194

Query: 183 LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAE 242
           + +G  +   GP+ E+ AE+R ++ +G D++ M  VPEV    HC++++ A+  IT    
Sbjct: 195 IRQGTLMFVSGPSLESNAELRFIRTLGMDMLAMDTVPEVTMGMHCNMRICALLIITYKDV 254

Query: 243 GL---SDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           G     DV + H Q L  A +   +  +L+C  +  I 
Sbjct: 255 GSEIGGDVSMEH-QMLETARVRITDLQSLVCNVIGTIT 291


>UniRef50_Q60367 Uncharacterized protein MJ0060 n=11 Tax=Methanococcales
           RepID=Y060_METJA
          Length = 252

 Score =  213 bits (542), Expect = 7e-54,   Method: Composition-based stats.
 Identities = 55/215 (25%), Positives = 97/215 (45%), Gaps = 5/215 (2%)

Query: 59  VSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAA 118
           ++T +G A  +++     V ++   G  H      +    + I   K LG E +   N+ 
Sbjct: 22  INTKYGKA-RVIIDKENEVVLLFRHGVRHNIPPHKINYRAN-IYALKKLGVERILAINSV 79

Query: 119 GSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE 178
           GSL+ ++  G      D I           ++ +       + + Y  E R +L+ +  +
Sbjct: 80  GSLKEDLKPGMFFVPNDFIEFTKKREETFYDEGK--VVHIDMTDPYCPELRNILKSILDK 137

Query: 179 EGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
             F   EGV+V   GP FET  EI + +  G DVVGM+  PEV+ AR  ++  V++  IT
Sbjct: 138 NNFSYGEGVYVCTEGPRFETKKEIAIYKNWG-DVVGMTGYPEVVLARELEMCYVSLCNIT 196

Query: 239 NMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFL 273
           N A G+S   L+  + L   +  +   + ++  F+
Sbjct: 197 NYACGISKNILTVDEVLEKIKEMENKILKVVEDFI 231


>UniRef50_D0JB48 Purine nucleoside phosphorylase n=2 Tax=Blattabacterium
           RepID=D0JB48_BLASB
          Length = 268

 Score =  212 bits (540), Expect = 1e-53,   Method: Composition-based stats.
 Identities = 78/264 (29%), Positives = 130/264 (49%), Gaps = 21/264 (7%)

Query: 19  TYKPDFTPRVAFIL-GSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGV 77
             K    P    +L GS    L ++I+N + ISYE++P F    ++G   + + G ++G 
Sbjct: 15  QNKIKEKPDFGILLLGSQFDKLIEEIQNPICISYEEIPLFSKKKLYG---KFLFGQIEGK 71

Query: 78  PVVCMKGRGHFYEGRGMTIMT--DAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKD 135
            VV +       E       T    I   K +G + L   N +G + P    G ++ +KD
Sbjct: 72  NVVFL------IEPFSEENRTNYFTIVLCKHIGIDKLILINISGGVNPNYKMGDVMLVKD 125

Query: 136 HINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPN 195
           HIN  P +P +   +D    RFF +   YD +   + + +A      + +GV+V++P  N
Sbjct: 126 HINFFPESPNI---NDLIKNRFFEITEPYDQKMLEIAENIAMNHNIIIQKGVYVAFPYSN 182

Query: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKL-----S 250
           ++T AE  M++ +GGD VGM++V +VI+AR  +L+V A+S I  M  GLS+ K+     S
Sbjct: 183 YKTYAEYAMIRSMGGDSVGMNIVTDVITARCMNLRVFAISIIV-MGMGLSEPKIQKNADS 241

Query: 251 HAQTLAAAELSKQNFINLICGFLR 274
                   E S    I ++  F++
Sbjct: 242 RNTFFQETEKSISLLILIVKEFIK 265


>UniRef50_D2RKT9 Purine or other phosphorylase family 1 n=1 Tax=Acidaminococcus
           fermentans DSM 20731 RepID=D2RKT9_ACIFE
          Length = 275

 Score =  212 bits (540), Expect = 1e-53,   Method: Composition-based stats.
 Identities = 66/252 (26%), Positives = 103/252 (40%), Gaps = 14/252 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I G+G       +E+A A  + KL    V T  G A  L  G   G  +  +   G
Sbjct: 3   KIGIIGGTG-------VEDASA--FGKLAPLTVETPFGQARCLK-GTAAGHEIYFLARHG 52

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + I   K LG   +    A GSL   +  G+ V     ++      
Sbjct: 53  LDHSVPPHKINYRAN-IFALKKLGVTEILSFTAVGSLNRGLPPGTFVVTSQLLDFTKSRV 111

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAEIR 203
               N +         A  Y    R  L +   + G     +G +V   GP +ETAAE+R
Sbjct: 112 NTFFNGENGQVAHVDFAQPYCPALRERLNRCLVKLGLRHSKQGTYVVTEGPRYETAAEVR 171

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
           M   +GGDV GM+ +PE + AR  ++     S +TNM  GL+   LSH +   A E  ++
Sbjct: 172 MYAAMGGDVAGMTNMPEAVLAREAEICYANCSVVTNMGSGLAVRSLSHEEVTEAMERLEK 231

Query: 264 NFINLICGFLRK 275
             + +I  ++  
Sbjct: 232 QILAVIEAYVND 243


>UniRef50_A4U101 Purine phosphorylase, family 2 n=4 Tax=Proteobacteria
           RepID=A4U101_9PROT
          Length = 291

 Score =  210 bits (536), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 55/256 (21%), Positives = 102/256 (39%), Gaps = 15/256 (5%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM-- 82
            P +  I GSG+  + D + N      +   G P       + +L+ G L G  +V +  
Sbjct: 3   KPVLGIIGGSGVYDI-DGLTNTQWRRVDSPFGQP-------SDDLLFGELNGQQLVFLPR 54

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            GRGH      +    + I   K  G   +   +A GSL+ E+  G+ V +   I+    
Sbjct: 55  HGRGHRIPPSELNYRAN-IDALKRAGVTEIVSVSAVGSLKEELPPGTFVIVDQFIDRTFA 113

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF-PLTEGVFVSYPGPNFETAAE 201
                           S+A+        ++++ AK+ G   +  G ++   GP F T AE
Sbjct: 114 RTKSFFETGLVA--HVSMAHPVCGRLGDIIEQAAKDAGIVAVRGGTYLVMEGPQFSTQAE 171

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQTLAAAEL 260
             + +  G DV+GM+ +PE   AR  ++    V+ +T+      D   ++  Q +     
Sbjct: 172 SNLYRQWGCDVIGMTNMPEAKLAREAEMCYATVAMVTDYDCWHPDHDAVTVEQVVKVLLE 231

Query: 261 SKQNFINLICGFLRKI 276
           +      L+   + ++
Sbjct: 232 NADRARALVKAIVPQV 247


>UniRef50_Q0BRD3 5'-methylthioadenosine phosphorylase n=113 Tax=cellular organisms
           RepID=Q0BRD3_GRABC
          Length = 319

 Score =  210 bits (534), Expect = 6e-53,   Method: Composition-based stats.
 Identities = 58/258 (22%), Positives = 100/258 (38%), Gaps = 15/258 (5%)

Query: 23  DFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM 82
              P +  I GSGL  + D +EN      E   G P       + +L+ G L GV  V +
Sbjct: 28  RIQPVIGIIGGSGLYDI-DGLENKEWRRVETPWGLP-------SDDLLFGTLDGVQCVFL 79

Query: 83  --KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
              GRGH      +    + I   K  GC  +   +A GSL+ ++  G  V +   I+  
Sbjct: 80  PRHGRGHRLSPSHLNYRAN-IDAMKRAGCTDILSLSAVGSLKKKLPPGHFVIVDQFIDRS 138

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETA 199
                    D        S+A+        ++++ AK    P   G  ++   GP F T 
Sbjct: 139 FAREKSFFGDGCVA--HVSVADPVCPRIGDVVEQAAKRLSLPYARGGTYLVMEGPQFSTR 196

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQTLAAA 258
           AE  + +  G  V+GM+ +PE   AR  ++    V+ +T+      D   ++    +   
Sbjct: 197 AESELYRSWGCSVIGMTNMPEAKLAREAEMCYATVAMVTDYDCWHEDHDHVTVDAVIRVL 256

Query: 259 ELSKQNFINLICGFLRKI 276
             + +    L+   +  +
Sbjct: 257 RGNAEKARALVQAVVPVL 274


>UniRef50_A3EWJ6 Methylthioadenosine phosphorylase n=2 Tax=Leptospirillum sp. Group
           II RepID=A3EWJ6_9BACT
          Length = 300

 Score =  208 bits (529), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 60/267 (22%), Positives = 106/267 (39%), Gaps = 20/267 (7%)

Query: 18  KTYKPDFTP---RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGE-LVLGH 73
           +T + +  P    V  I GSGL  +       + I  E++    V T  G + +  ++G 
Sbjct: 5   RTKRGEGNPGSGPVGIIGGSGLYQM-----EGLTIEEERV----VETPWGVSSDPYLIGK 55

Query: 74  LQGVPVVCM--KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
           +  +PVV +   G+GH Y    +    + +   K LG   +   +A GSL+ E+  G +V
Sbjct: 56  VGTLPVVFLSRHGKGHRYLPSEINYRAN-LAGLKSLGVSRVLSVSAVGSLKEEIAPGDMV 114

Query: 132 ALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVS 190
            + D I+     PM    +   G           ++         +  G P   G  ++ 
Sbjct: 115 LVDDFIDLTRQRPMSFYGNGAVG--HTPYGRPVCSDLFEAFSGACEHLGLPTHRGGTYIC 172

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-L 249
             GP F T AE R+ +  G DV+GM+   E   AR   L    ++  T+      D   +
Sbjct: 173 MEGPAFSTRAESRLYRQWGADVIGMTNGTEARLAREIGLCYATLALATDYDCWHPDHDMV 232

Query: 250 SHAQTLAAAELSKQNFINLICGFLRKI 276
           + A  +     + +    ++   L +I
Sbjct: 233 TVADVIRIMNQNVRRANTILLDALERI 259


>UniRef50_Q18KQ3 5'-methylthioadenosine phosphorylase MtaP n=4 Tax=Halobacteriaceae
           RepID=Q18KQ3_HALWD
          Length = 301

 Score =  208 bits (529), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 63/257 (24%), Positives = 107/257 (41%), Gaps = 17/257 (6%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVH-GHAGELVLGHLQGVPVVCMKGR 85
            + FI GSG+   A  ++N   I  E   G P + +  G  GE       G  V+ +   
Sbjct: 5   TIGFIGGSGIYE-ALGLQNTHTIEIETPFGEPAAPLTVGEVGET------GREVIFLPRH 57

Query: 86  G--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           G  H Y    +    + I   K  G   +  +NA GSLR E+    LV      +     
Sbjct: 58  GTSHEYSPTTVPYRAN-IFALKQAGVTHVIASNAVGSLREEISPRMLVIPDQIYDRTKHR 116

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP----LTEGVFVSYPGPNFETA 199
                +D     +    A  Y  E R+++  VA E        + +G +V   GP F T 
Sbjct: 117 TSTFFSDGIVAHQ--QFATPYCTELRSIVTDVAMENTAADIDIVKDGTYVCIEGPQFSTR 174

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAE 259
           AE    +  G D++GM+ +PE   AR  +L  V ++ +T+      D +++  + L+ AE
Sbjct: 175 AESEFYRSQGWDIIGMTTIPEAKLAREAELAYVTIAGVTDYDVWKEDTQVTLEEVLSNAE 234

Query: 260 LSKQNFINLICGFLRKI 276
            +++   +++   +  I
Sbjct: 235 RNQKAIKSVLTAVINTI 251


>UniRef50_Q3ZZT2 Methylthioadenosine phosphorylase n=7 Tax=cellular organisms
           RepID=Q3ZZT2_DEHSC
          Length = 294

 Score =  207 bits (528), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 58/255 (22%), Positives = 105/255 (41%), Gaps = 15/255 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM--KG 84
           ++  I G+GL  + + + +    + +   G P       +  +V G+L GV V  +   G
Sbjct: 6   KIGVIGGTGLYDI-EGLTDIREHTLDTPFGKP-------SDIIVTGNLNGVGVAFLPRHG 57

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           RGH      +    + I   K LG E +   N+ GS + EV  G L+     I+      
Sbjct: 58  RGHRILPSEIPSRAN-IYALKSLGVEHIIAVNSVGSFKKEVKPGHLLIPDQLIDRTSQRT 116

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIR 203
                         + +  +    R LL + AKE G  +  G  +V   GP F T AE R
Sbjct: 117 NTFFGKGIVA--HIAFSQPFCPNLRKLLFECAKEAGANVHNGGTYVVMEGPAFSTQAESR 174

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQTLAAAELSK 262
           + +  G DV+GM+ +PE   AR  ++    ++  T+      + + ++  + +A    + 
Sbjct: 175 LHKSWGADVIGMTALPEAKLAREAEICYAIIACATDYDAWHEEEEAVTVDKVIATLRGNI 234

Query: 263 QNFINLICGFLRKIA 277
                +I   + +I+
Sbjct: 235 NLSKEIIKLAIGRIS 249


>UniRef50_B9KZC3 Methylthioadenosine phosphorylase n=2 Tax=Bacteria
           RepID=B9KZC3_THERP
          Length = 289

 Score =  207 bits (528), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 56/254 (22%), Positives = 100/254 (39%), Gaps = 14/254 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVC--MKG 84
            +  I GSGL  + + + +   I+ E   G P  T+        LG L G+ V      G
Sbjct: 4   ELGVIGGSGLYRMPE-LTDVEEIAIETPFGRPSDTIT-------LGTLHGMRVAFIPRHG 55

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H +    +    +     K LG + +   +A GSLR E+     V     ++     P
Sbjct: 56  RAHQHSPSNVPARAN-FWALKSLGVQWVVSVSAVGSLREEIAPLDFVVPDQVVDRTVRRP 114

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIR 203
               ++        +L   +  E R  L + A   G  + + G ++   GP F T AE  
Sbjct: 115 RSFFDESGL-VVHVTLDEPFCPELRWALTQAAIAAGVRVHDRGTYICIEGPQFSTRAESN 173

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL-SDVKLSHAQTLAAAELSK 262
           + +  G D++GM+ +PEV  AR  +L    ++ +T+       +  +S +  L     + 
Sbjct: 174 LYRSWGLDIIGMTAMPEVRLAREAELCFALLALVTDYDVWHAEEEPVSVSVVLERLHQNV 233

Query: 263 QNFINLICGFLRKI 276
           Q     +   +  +
Sbjct: 234 QAAQRALSALIEYL 247


>UniRef50_Q465I0 Methylthioadenosine phosphorylase n=4 Tax=Methanosarcinaceae
           RepID=Q465I0_METBF
          Length = 258

 Score =  207 bits (527), Expect = 4e-52,   Method: Composition-based stats.
 Identities = 66/252 (26%), Positives = 109/252 (43%), Gaps = 21/252 (8%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
            +A + G G  +            Y++     V+T +G    + L  ++G  VV +    
Sbjct: 9   EIAVLGGVGFNS------------YQEFESQLVNTPYGEVT-VYLTTVRGKKVVVIPRHA 55

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             +      +    + I     +G + +  TN+ GS+R     GS V L D I+     P
Sbjct: 56  GENHIPPHRINYRAN-IWAVYSIGAKRVISTNSVGSMRGH-PVGSFVVLDDFIDFTRNRP 113

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
               +D         ++  Y  E R  L+   +++G P TEG++    GP FET AEIRM
Sbjct: 114 STFYDDRTA---HVDVSEPYCPEIRIALRDALEKQGLPYTEGIYACTEGPRFETRAEIRM 170

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           M     DVVGM+ VPEV  A+   L   +++ +TN A G++  KL+  +       ++  
Sbjct: 171 MSQF-ADVVGMTGVPEVGLAKELSLCYASLAIVTNQACGMTTQKLTADEVTEVVGKAQDA 229

Query: 265 FINLICGFLRKI 276
              +I   + KI
Sbjct: 230 IFEIISDTIEKI 241


>UniRef50_C0W9U9 Purine nucleoside phosphorylase n=1 Tax=Acidaminococcus sp. D21
           RepID=C0W9U9_9FIRM
          Length = 268

 Score =  207 bits (527), Expect = 4e-52,   Method: Composition-based stats.
 Identities = 64/251 (25%), Positives = 102/251 (40%), Gaps = 12/251 (4%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I G+G       +E+     +  L    V T  G A E   G +    V  +   G
Sbjct: 3   KIGIIGGTG-------VEDTSI--FGTLSLITVETPFGTA-EGFAGKIDDTSVYFIARHG 52

Query: 87  HFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
             +      I   A I   K LG   +    A GSL   +  G+ V     ++       
Sbjct: 53  KGHSLPPHRIPYRANIYALKKLGVTEILSFTAVGSLNRGLIPGTFVNTSQILDFTKSREH 112

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRM 204
              +           +  Y    R  L  +    G   ++ G +V+  GP +ETAAE+RM
Sbjct: 113 TFFDGGVMPVCHVDFSFPYCPVLRERLNGILTRLGVRHSKAGCYVATEGPRYETAAEVRM 172

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
             ++GGDV GM+ +PE + AR  ++     S +TNM  GLS   LSH + +A  + + + 
Sbjct: 173 YGLMGGDVAGMTQMPEAVLAREAEICYANCSLVTNMGSGLSWTALSHEEVVAMMDENAKT 232

Query: 265 FINLICGFLRK 275
              +I  FL +
Sbjct: 233 IARIIHAFLTE 243


>UniRef50_A9BDU8 5'-methylthioadenosine phosphorylase n=13 Tax=Cyanobacteria
           RepID=A9BDU8_PROM4
          Length = 316

 Score =  207 bits (526), Expect = 4e-52,   Method: Composition-based stats.
 Identities = 56/258 (21%), Positives = 110/258 (42%), Gaps = 18/258 (6%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM--KG 84
           R+  + GSGL ++ + +EN   I  +   G P       + +L LG L G+ VV +   G
Sbjct: 24  RLGVLGGSGLYSI-NNLENIKEIEIDTPYGKP-------SDKLRLGILGGMEVVFLARHG 75

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H +   G+    + I   + LG   +   +A GSL+ +V    +V     I+     P
Sbjct: 76  RHHTFTPTGIPYRAN-IWALRSLGVRWILAPSAVGSLQEQVRPLDMVVPDQFIDRTHQRP 134

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE---GFPLTEG-VFVSYPGPNFETAA 200
           +   +D        ++A+ +      LL +  ++    G  L  G ++++  GP F T A
Sbjct: 135 LTFFSDG--AVAHVTMADPFCPTLSRLLTEEGQKLMPEGRQLHRGGIYLAMEGPAFSTRA 192

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VKLSHAQTLAAAE 259
           E ++ +  G  V+GM+   E   AR  ++   ++S +++          +S    +   +
Sbjct: 193 ESQLYRSWGCTVIGMTNHTEARLAREAEIAYASISMVSDYDCWHEGYGNVSVDMVIENLQ 252

Query: 260 LSKQNFINLICGFLRKIA 277
            +      ++    +K+A
Sbjct: 253 TNASVANKIVEATAKKVA 270


>UniRef50_C5EEL8 Purine nucleoside phosphorylase n=1 Tax=Clostridiales bacterium
           1_7_47FAA RepID=C5EEL8_9FIRM
          Length = 259

 Score =  206 bits (524), Expect = 9e-52,   Method: Composition-based stats.
 Identities = 64/256 (25%), Positives = 100/256 (39%), Gaps = 19/256 (7%)

Query: 24  FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
             P V  I GSG   L   +EN           F  +  +G + E+  G +QG  V  + 
Sbjct: 1   MKP-VGIIGGSGFYEL---LENPRM--------FVHNNKYGRSSEIFEGTIQGRKVYFLP 48

Query: 84  GRGHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
             G  ++     I   A I  FK LG E +  TN  GS  P++  GSLV   D  +    
Sbjct: 49  RHGEEHKIIVPRINYRANIWAFKELGVEQILATNCVGSSNPDIELGSLVIPHDFCDWTRR 108

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE--GFPLTEGVFVSYPGPNFETAA 200
            P   L DD        +  AY  + R  L   A +   G    + V     G  FET  
Sbjct: 109 FP-RSLYDDEVEAYHVDMTPAYCPDLRRALIDAANKVKPGHVHDKAVIFVNEGLRFETPF 167

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAEL 260
           E+ M + +G D++GM+ +PE + AR   +    +   TN   G    ++         + 
Sbjct: 168 ELTMFRKLGADLIGMTTLPEAVFAREAAICYAHICVPTNWCLG---EQIEADDFPRLLKQ 224

Query: 261 SKQNFINLICGFLRKI 276
             ++F  ++   +  +
Sbjct: 225 GIEDFKQVLYLAIPDL 240


>UniRef50_Q1NY44 Methylthioadenosine phosphorylase n=2 Tax=delta proteobacterium
           MLMS-1 RepID=Q1NY44_9DELT
          Length = 251

 Score =  206 bits (524), Expect = 9e-52,   Method: Composition-based stats.
 Identities = 72/256 (28%), Positives = 103/256 (40%), Gaps = 18/256 (7%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL-GHLQGVPVVCM--KG 84
           +A I GSGL       +N      E+   F V T +G     +L G L G  VV +   G
Sbjct: 4   IAIIGGSGL-------DNPEFFDVEQ--EFTVETPYGPPSAPLLQGRLDGREVVLLARHG 54

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H      +    + +   +  GCE +  T A+GSLR E+G G LV     I+     P
Sbjct: 55  RQHTIPPSRVNNRAN-LFALREAGCERIIATAASGSLRNEIGPGHLVIPDQFIDFTRQRP 113

Query: 145 MVGLNDDRFG---ERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAA 200
           +   ++   G        LA+ +D   R  +     E   PL   G  ++  GP F T A
Sbjct: 114 LTFYDEFPAGIENACHTPLADPFDETLRQKIIAAGGERQIPLHTSGTILTIEGPRFSTRA 173

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDV-KLSHAQTLAAAE 259
           E RM Q  G D+V M+V PE I A    L    ++ +T+      D   L   Q +    
Sbjct: 174 ESRMYQSWGADLVNMTVAPEAILAAELKLPYAVIAMVTDYDSWKEDEPPLLVPQLVTVFR 233

Query: 260 LSKQNFINLICGFLRK 275
            + +    LI   L  
Sbjct: 234 SNIEKITTLIRQTLAT 249


>UniRef50_B4U6Q8 Purine phosphorylase family 2 n=2 Tax=Aquificaceae
           RepID=B4U6Q8_HYDS0
          Length = 280

 Score =  204 bits (519), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 56/269 (20%), Positives = 98/269 (36%), Gaps = 36/269 (13%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +  I GSGL  + D +E    +  +   G P S +    G           V  +   G 
Sbjct: 9   LGIIGGSGLYKIFDDVE---ELDIDTPFGKPSSKIFLKNG-----------VAFLSRHGI 54

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H      +    + I     +G   L    A G +     +G +V   D ++       
Sbjct: 55  DHSIPPHLVNYRAN-IYALYKIGVRKLISIGATGGINTLFKSGDIVITSDVLDFTNSRAS 113

Query: 146 VGLN-----------DDRFG-------ERFFSLANAYDAEYRALLQKVAKEEGFPLT-EG 186
                          D  F             ++N +  E   +   ++K+       +G
Sbjct: 114 TFFEGIFSKDIKEQEDTPFYRLLKAKKVVHTDMSNIFCEEMIGIANGISKDLSLHFYVKG 173

Query: 187 VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD 246
           V+    GP FET  E+ M++ +G D+VGM+  PEV  AR   + ++ +S ITN A G+  
Sbjct: 174 VYACTEGPRFETKKEVEMLKHLGADMVGMTACPEVFLARETGMHILHISVITNPAAGIEG 233

Query: 247 VKLSHAQTLAAAELSKQNFINLICGFLRK 275
            KL+  + +   +   +     +  F+ K
Sbjct: 234 HKLTSKEVIDMMKQKDEEIKKFLTLFIPK 262


>UniRef50_D1YZM1 5'-methylthioadenosine phosphorylase n=1 Tax=Methanocella
           paludicola SANAE RepID=D1YZM1_METPS
          Length = 281

 Score =  203 bits (517), Expect = 5e-51,   Method: Composition-based stats.
 Identities = 56/255 (21%), Positives = 105/255 (41%), Gaps = 20/255 (7%)

Query: 27  RVAFILGSGLGA--LADQIENAVAISYEKLPGFPVSTVHGHAGE-LVLGHLQGVPVVCM- 82
           +V  I GSG+    + D ++              V T  G  G+  ++G + G+  V + 
Sbjct: 3   KVGIIGGSGIYDPSMFDHVKEQK-----------VRTPFGTPGDSFIVGSMNGIEAVFLS 51

Query: 83  -KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMP 141
             GRGH Y    +    + I   K LG   +   +A GSL+  +    +V      +   
Sbjct: 52  RHGRGHKYSPTDLNYRAN-IYGMKKLGVTHIISVSAVGSLKESLKPLDIVIPDQVYDRTT 110

Query: 142 GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAE 201
                            S A+ +  +   +L + AKE+      G ++   GP F T AE
Sbjct: 111 KRVSTYFEGGIVA--HISFADPFCRKLSDILYETAKEKYRVHNGGTYLCMEGPQFSTKAE 168

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELS 261
            R+ + +G DV+GM+ +PE   AR  ++    ++ IT+      +  +S  Q +  A  +
Sbjct: 169 SRIYRKLGFDVIGMTALPEAKLAREAEICFAILATITDYDVWY-EEPVSIGQVIEYAAKN 227

Query: 262 KQNFINLICGFLRKI 276
           ++   +++   + +I
Sbjct: 228 EEAVKDILRRAVGRI 242


>UniRef50_C6HVW5 Methylthioadenosine phosphorylase n=1 Tax=Leptospirillum
           ferrodiazotrophum RepID=C6HVW5_9BACT
          Length = 307

 Score =  203 bits (517), Expect = 6e-51,   Method: Composition-based stats.
 Identities = 62/266 (23%), Positives = 102/266 (38%), Gaps = 21/266 (7%)

Query: 18  KTYKPDFTPRVAFILGSGLG---ALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL 74
           +  K +    +  I GSGL     L+D +   V   + + P  P  T          G L
Sbjct: 5   RKRKSEEMAPIGVIGGSGLYQLKGLSDLVPTVVETPWGQ-PSDPYMT----------GSL 53

Query: 75  QGVPVVCMKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            GVPVV +   G  H Y    +    + I  F  LG + +   +A GSLR ++  G +V 
Sbjct: 54  GGVPVVFLSRHGSGHRYLPGEVNYRAN-IAGFVALGVKRILSVSAVGSLREDIVPGDMVV 112

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSY 191
           +   I+   G P         G    + A+    +    L    +  G     +G +   
Sbjct: 113 IDQFIDGTRGRPSTFYGQGAVG--HTAFAHPICPDLAQTLIGACRTAGVRHHVKGTYYCM 170

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LS 250
            GP F T AE  + +  G  V+GM+ V E   AR   L    ++  T+      D   ++
Sbjct: 171 EGPAFSTQAESFLYRQFGAHVIGMTNVTEARLAREAGLCYATLALSTDFDCWHPDHDAVT 230

Query: 251 HAQTLAAAELSKQNFINLICGFLRKI 276
            ++ LA    + +N   ++   L  +
Sbjct: 231 VSEVLAVISKNVENANRILEHALSSV 256


>UniRef50_Q16MW6 Methylthioadenosine phosphorylase n=6 Tax=Neoptera
           RepID=Q16MW6_AEDAE
          Length = 279

 Score =  203 bits (517), Expect = 6e-51,   Method: Composition-based stats.
 Identities = 59/227 (25%), Positives = 99/227 (43%), Gaps = 9/227 (3%)

Query: 59  VSTVHGHAGELVL-GHLQGVPVVCM--KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCT 115
           VST  G+  ++++ G + GV  V +   GR H      +    + I   K +GC  +  +
Sbjct: 29  VSTHFGNPSDVLIEGKIAGVDCVLLARHGRNHSIMPSNVNYRAN-IWALKTVGCTHVIVS 87

Query: 116 NAAGSLRPEVGAGSLVALKDHINTMPGTPMVGL--NDDRFGERFFSLANAYDAEYRALLQ 173
            A GSL+  +  G LV   + I+            ND   G     +  A+ +  R +L 
Sbjct: 88  TATGSLQERIHPGDLVIPDNFIDRTTKRAQTFYDGNDMLVGVCHVPMEPAFCSRTREVLI 147

Query: 174 KVAKEEGFP--LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKV 231
           + AKE G      +G  V+  GP F + AE  + +  G D+V M++VPEV+ A+   L  
Sbjct: 148 ETAKELGLVGVHNKGTVVTIEGPRFSSKAESNLFRQWGADLVNMTLVPEVVLAKEAGLCY 207

Query: 232 VAVSAITNMAEG-LSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
            A++  T+          ++ A  +A  + +      LI   + KIA
Sbjct: 208 AAIAMATDYDCWRDCGENVNVADVMATFKKNVTKVTQLITAVIPKIA 254


>UniRef50_D1A6L7 Methylthioadenosine phosphorylase n=16 Tax=Actinomycetales
           RepID=D1A6L7_THECD
          Length = 279

 Score =  203 bits (517), Expect = 6e-51,   Method: Composition-based stats.
 Identities = 54/259 (20%), Positives = 99/259 (38%), Gaps = 17/259 (6%)

Query: 22  PDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVC 81
              T  +  I GSG  +  D IE     +    P  P++          +G + G  V  
Sbjct: 12  TTSTATIGVIGGSGFYSFLDDIEEVRLDTPYGPPSDPIA----------VGTVAGRTVAF 61

Query: 82  MKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINT 139
           +   G  H Y    +    + +   + LG   +   +A GSL P+ G G+L      ++ 
Sbjct: 62  IPRHGRDHRYPPHKIPYRAN-LWALRSLGVRQVLAPSAVGSLVPQYGPGTLAVPDQLVDR 120

Query: 140 MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF-PLTEGVFVSYPGPNFET 198
             G        +  G    S A+ Y    R ++   A++  + P+  G  V   GP F T
Sbjct: 121 TYGRVQTFY--EEGGAIHVSFADPYCPVGRRVVLDTARKADWEPVDGGTLVVIEGPRFST 178

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQTLAA 257
            AE +     G  +VGM+  PE + AR   L    +  +T++  G+ + + ++  +    
Sbjct: 179 RAESQWYAAQGWTLVGMTGHPEAVLARELALCYTPICLVTDLDAGIEEGEGVTMEEVFRV 238

Query: 258 AELSKQNFINLICGFLRKI 276
              +     +L+   +  +
Sbjct: 239 FAKNVNRLRSLVTAVVEAL 257


>UniRef50_Q5Z1K2 Putative methylthioadenosine phosphorylase n=4
           Tax=Corynebacterineae RepID=Q5Z1K2_NOCFA
          Length = 269

 Score =  203 bits (516), Expect = 7e-51,   Method: Composition-based stats.
 Identities = 67/256 (26%), Positives = 103/256 (40%), Gaps = 18/256 (7%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAG-ELVLGHLQGVPVVCMK 83
            P +A I G+G     D     V I           T +G     + +G + G PV  + 
Sbjct: 6   RPALAVIGGTGFYDFFDTATQDVEID----------TPYGAPSAPIAVGEVAGRPVAFVP 55

Query: 84  GRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMP 141
             G  H Y    +  + + +   + LG   +F   A GSLR + G G++   +  ++   
Sbjct: 56  RHGKRHEYAPHTLPYLAN-MWALRSLGVRRIFAPCAVGSLRADWGPGTVAVPEQLVDRTS 114

Query: 142 GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAE 201
           G P    +    G    S A+ Y  E R      A EE      G  V   GP F T AE
Sbjct: 115 GRPQTYFDG---GGVHVSFADPYCDELRGAAIGSAVEELPMQPGGTMVVVQGPRFSTRAE 171

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA-QTLAAAEL 260
            R     G D+V M+  PE + AR  ++   AV+ +T++  GL   +  HA    A  + 
Sbjct: 172 SRWFAGQGWDLVNMTGYPEAVLARELEMCYCAVALVTDLDAGLESGEGVHAVDVFAEFKR 231

Query: 261 SKQNFINLICGFLRKI 276
           + + F  LI G +  +
Sbjct: 232 NIEPFKELIRGAISAV 247


>UniRef50_B1GZW8 S-methyl-5'-thioadenosine phosphorylase n=1 Tax=uncultured Termite
           group 1 bacterium phylotype Rs-D17 RepID=B1GZW8_UNCTG
          Length = 293

 Score =  202 bits (515), Expect = 8e-51,   Method: Composition-based stats.
 Identities = 60/254 (23%), Positives = 107/254 (42%), Gaps = 14/254 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM--KG 84
           ++AFI GSGL  + D IEN V    +   G P       + +++ G +  +    +   G
Sbjct: 9   KIAFIGGSGLYQI-DGIENIVEKDIDTPFGRP-------SDKIITGVINRINCAFLPRHG 60

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           RGH      +    + I   K LG E +    A GSL+ E+     V      +      
Sbjct: 61  RGHILNPSEINQRAN-IYALKSLGTEQIVSFTACGSLKEEIKPKDFVIPDQVFDRTKNRS 119

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIR 203
           +     ++      S+A  +  E R+L+++   E G      G +V   GP F T AE +
Sbjct: 120 LTFF--EKGIVAHVSMAYPFCNEIRSLIRQTVYEIGIKYHFCGTYVCIEGPQFSTKAESQ 177

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
           + +  G  VVGM++ PE   AR  ++    +S +T+        ++++   +A    +  
Sbjct: 178 INRQSGFSVVGMTLFPEAKLAREAEICYANISLVTDFDVWKEREEVTNDAVVANVAANVA 237

Query: 264 NFINLICGFLRKIA 277
           N   +I   + K++
Sbjct: 238 NSRRVIKSLILKLS 251


>UniRef50_Q2S4Q1 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Salinibacter ruber DSM 13855 RepID=Q2S4Q1_SALRD
          Length = 285

 Score =  202 bits (515), Expect = 9e-51,   Method: Composition-based stats.
 Identities = 73/214 (34%), Positives = 105/214 (49%), Gaps = 5/214 (2%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           +P VA +    L  +         I Y  LP +P S      G L +G L G  VV +  
Sbjct: 35  SPTVAIVRDVELDDVLQAGTVEHTIPYANLPHYPAS-----DGTLTIGTLGGTQVVELDQ 89

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H Y+G     ++  +R     G + L     AGS+  +   G L+ L DHIN     P
Sbjct: 90  AFHLYDGHTPREVSFPVRMLATAGIDSLLLAAPAGSVTAQADRGDLMLLTDHINFQGQNP 149

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           +VG N + +G RF  +   YDA  R      A+  G PL +G+++   GP+ ET AE RM
Sbjct: 150 LVGPNVEEWGPRFPDMTAPYDATLRQRASDAARSAGVPLRQGIYMGLLGPHHETTAEHRM 209

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
              +G DVVG  VVPEV++ARH  + V+A++ +T
Sbjct: 210 AHRLGADVVGTGVVPEVLAARHMGVHVMALTLLT 243


>UniRef50_Q87ZC3 Probable S-methyl-5'-thioadenosine phosphorylase n=45 Tax=cellular
           organisms RepID=MTNP_PSESM
          Length = 246

 Score =  201 bits (511), Expect = 3e-50,   Method: Composition-based stats.
 Identities = 61/248 (24%), Positives = 94/248 (37%), Gaps = 10/248 (4%)

Query: 29  AFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHF 88
           A I G+GL  L + +    ++      G P       +GE+ +G   G  V+ +   GH 
Sbjct: 5   AIIGGTGLTQL-EGLNIRQSLPMNTPYGAP-------SGEIQIGDYAGREVMFLARHGHP 56

Query: 89  YEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG 147
           +      +   A I   K  G E +   NA G + P +G G      D ++   G     
Sbjct: 57  HRLPPHQVNYRANIWALKQAGAEAILAVNAVGGIHPAMGTGHFCVPHDLVDYTSGRQHTF 116

Query: 148 LNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAEIRMMQ 206
             DD         +  Y    R  L      EG      GV+    GP  ET AEI  ++
Sbjct: 117 FADDLEEVTHIDFSYPYSEALRVRLVAALAAEGCAFSDRGVYACTQGPRLETVAEIIRLE 176

Query: 207 IIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFI 266
             G D+VGM+ +PE   AR  +L+   ++ + N A G S   ++ A+   A         
Sbjct: 177 RDGCDIVGMTGMPEAALARELELEYACLALVVNPAAGKSTAVITMAEIEQALRDGMGKVK 236

Query: 267 NLICGFLR 274
             +   L 
Sbjct: 237 ATLARVLS 244


>UniRef50_Q21JS6 Methylthioadenosine phosphorylase n=1 Tax=Saccharophagus degradans
           2-40 RepID=Q21JS6_SACD2
          Length = 252

 Score =  201 bits (511), Expect = 3e-50,   Method: Composition-based stats.
 Identities = 62/255 (24%), Positives = 98/255 (38%), Gaps = 17/255 (6%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++A I GSG   +A    NA A++       PV+T +G  G L+   + G  +V +   G
Sbjct: 4   KIAVIGGSGFYTMASA-NNAKALN-------PVNTPYGSVGGLIEYSMGGHNIVFLARHG 55

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + I   K LG   +   NA G +    G G LV     I+   G  
Sbjct: 56  GEHKLPPHKINYRAN-IYALKELGVSHIIAANAVGGIGERCGPGVLVIPDQLIDYTFGRE 114

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE------EGFPLTEGVFVSYPGPNFET 198
               +    G         ++   R  L + +            +  GV+    GP  ET
Sbjct: 115 GTFFDSFEDGMSHIDFTYPFEGRVRNALIQASAAFEKEFGSDKVVRNGVYACMQGPRLET 174

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
           AAEI+ ++  G  +VGM+ +PE   AR   +   ++  + N A GLS   ++     A  
Sbjct: 175 AAEIKKLKNDGASLVGMTAMPEAALARELGIDYASICLVVNWAAGLSAGLITLEAINAEL 234

Query: 259 ELSKQNFINLICGFL 273
           E        LI   +
Sbjct: 235 EGCVGKAEYLIGQSV 249


>UniRef50_D1C2Y0 Methylthioadenosine phosphorylase n=2 Tax=Bacteria
           RepID=D1C2Y0_SPHTD
          Length = 295

 Score =  200 bits (508), Expect = 6e-50,   Method: Composition-based stats.
 Identities = 59/253 (23%), Positives = 98/253 (38%), Gaps = 13/253 (5%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           V  I GSGL  +   + +   +      G P       +  L +G L GV V  +   G 
Sbjct: 9   VGVIGGSGLYKMPY-LTDVEEVEINTPFGPP-------SAPLAIGTLAGVRVAFLPRHGR 60

Query: 88  FYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
            +E     +   A     K +G   +   +A GSLR ++    LV     ++     P  
Sbjct: 61  HHEYHPSRVPARANFWALKAVGVRRVISVSAVGSLREDIHPLDLVVPDQVVDRTVDRPRT 120

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRMM 205
               D        LA+ +  E RA L   A      +   G ++   GP F T AE  + 
Sbjct: 121 FF--DTAPVVHVELADPFCPEVRAALITAANSVAPRVHSSGTYLCIEGPQFSTRAESELH 178

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG-LSDVKLSHAQTLAAAELSKQN 264
           +  G D+VGM+ +PEV  AR  +L    ++ +T+      S   +S AQ +     + + 
Sbjct: 179 RRWGMDLVGMTAMPEVRLAREAELCFGILALVTDYDVWHESAEDVSVAQVIQNLHQNVET 238

Query: 265 FINLICGFLRKIA 277
              ++   +  +A
Sbjct: 239 AQAVLRAVIPSLA 251


>UniRef50_Q0F2U5 Purine nucleoside phosphorylase n=1 Tax=Mariprofundus ferrooxydans
           PV-1 RepID=Q0F2U5_9PROT
          Length = 290

 Score =  199 bits (506), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 55/252 (21%), Positives = 97/252 (38%), Gaps = 15/252 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM--KG 84
           R   I GSGL  +A  +E    ++ +   G P       + ELVL  +    VV +   G
Sbjct: 8   RTGIIGGSGLYNIA-GVEIIDTLTIDTPYGAP-------SDELVLARIGDQEVVFLPRHG 59

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H      +    + +   KL G   +   +A GSLR  +  G  V +   ++      
Sbjct: 60  RNHSIPPHKINYRAN-VYAMKLAGVNRIISISAVGSLRKHIHPGEFVLVDQFVDRTHSRE 118

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIR 203
               +         S+A+    + R+ L++     G     G  ++   GP F + AE  
Sbjct: 119 NTFFDGPIVA--HVSIADPVCNQLRSALEQACLASGITTHNGGRYLVMQGPQFSSRAESE 176

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS-DVKLSHAQTLAAAELSK 262
           + +  G DV+GM+ +PE   AR  ++    V+  T+       +  +S    L   + + 
Sbjct: 177 LYRSWGMDVIGMTNMPEAKLAREAEICYATVAMCTDYDCWHGQEEDVSVQSILEVMQANV 236

Query: 263 QNFINLICGFLR 274
            N   ++  F  
Sbjct: 237 ANTQRMLQAFFA 248


>UniRef50_P74469 Sll0135 protein n=67 Tax=cellular organisms RepID=P74469_SYNY3
          Length = 326

 Score =  197 bits (502), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 55/269 (20%), Positives = 99/269 (36%), Gaps = 18/269 (6%)

Query: 16  IIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQ 75
            I+         +  I GSGL  + + ++N   ++ +   G P       +   ++G L 
Sbjct: 26  FIRKNSTMVNAPIGIIGGSGLYQM-EALKNVEEVTLDTPFGAP-------SDSFIVGELA 77

Query: 76  GVPVVCM--KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVAL 133
           GV V  +   GRGH      +    + I   K LG + L   +A GSL+ E     +V  
Sbjct: 78  GVRVAFLARHGRGHHLLPSEIPFRAN-IHGMKQLGVKYLISASAVGSLQAEAKPLDMVVP 136

Query: 134 KDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP----LTEGVFV 189
              I+           +           N    +    L                 G +V
Sbjct: 137 DQFIDRTRQRISTFFGEGIVA--HIGFGNPICPQLAQCLSTAIAGLELEGVTLHDRGTYV 194

Query: 190 SYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK- 248
           S  GP F T AE  + +  GG V+GM+ +PE   AR  ++    ++ +T+      D   
Sbjct: 195 SMEGPAFSTIAESNLYRSWGGTVIGMTNLPEAKLAREAEIAYATLALVTDYDCWHPDHDH 254

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKIA 277
           ++    +   + +  N   +I   ++++A
Sbjct: 255 VTVEMVIGNLQKNAVNAQQVILETVKQLA 283


>UniRef50_Q47F96 Methylthioadenosine phosphorylase n=7 Tax=Betaproteobacteria
           RepID=Q47F96_DECAR
          Length = 256

 Score =  197 bits (500), Expect = 5e-49,   Method: Composition-based stats.
 Identities = 57/251 (22%), Positives = 102/251 (40%), Gaps = 14/251 (5%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH-AGELVLGHLQGVPVVCMKGRG 86
           +A I GSGL  L++   +   +         V T +G  +G LV G + G P V +   G
Sbjct: 2   LAIIGGSGLTTLSNLDVSHREV---------VRTPYGEASGALVFGQICGQPAVFLPRHG 52

Query: 87  HFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
           + +      +   A +          +    + GS+R ++  G +V     I+   G   
Sbjct: 53  YGHTIPPHMVNYRANMWALHHHKVSGVISVASVGSIRGDLQPGDIVLPHQIIDYTWGRKS 112

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIRM 204
              + +          + YD E R  + +  ++    +  G V+ +  GP  ETAAEI  
Sbjct: 113 TFFDGNGTPVNHIDFTDPYDPELRRRILEAGEQLSIDVKVGAVYAATQGPRLETAAEINR 172

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS-HAQTLA-AAELSK 262
           ++  G DVVGM+ +PE + AR       A++ + N A G  +     H ++L    + + 
Sbjct: 173 LERDGADVVGMTGMPEAVLARELGTPYAAINVVANHAAGRGNSANGIHFESLEPVLQEAM 232

Query: 263 QNFINLICGFL 273
                +I   +
Sbjct: 233 GRVKAIIEKLV 243


>UniRef50_C7LA98 FI12502p (Fragment) n=14 Tax=Drosophila RepID=C7LA98_DROME
          Length = 304

 Score =  197 bits (500), Expect = 5e-49,   Method: Composition-based stats.
 Identities = 56/263 (21%), Positives = 105/263 (39%), Gaps = 26/263 (9%)

Query: 27  RVAFILGSGLGA---LADQIENAVAISYEKLPGFPVSTVHGHAGELVL-GHLQGVPVVCM 82
           ++  I  + L     LA+++E            + V T  G   ++++ G ++GV V  +
Sbjct: 33  KIGIIGEANLDKPIYLAERME------------YAVCTPFGKPSDVIIDGQIEGVNVCLL 80

Query: 83  --KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
              GR H      +    + +   + +GC  +  TN   SLR     G LV   D I+  
Sbjct: 81  SRNGRNHDIMPSNINYRAN-VWAMRKMGCTHILVTNTFSSLRDTFQPGHLVVPNDVIDYT 139

Query: 141 PGTPMVGLND---DRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNF 196
                   +       G     +   +    R  L   A+E GFP  + G  ++  GP +
Sbjct: 140 SRRAQTFYDGAVGSPLGVCHVPMNPTFCERTRQHLLSAAEELGFPTGSSGTVLTLEGPRY 199

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK--LSHAQT 254
            T AE  M +  G D++ M++ PE I A+   +   ++  +TNM    +      +H + 
Sbjct: 200 STVAENNMFRKWGADLLSMTLCPEAILAKEAGIPYASLGLVTNMECWCAKQPNATTH-EI 258

Query: 255 LAAAELSKQNFINLICGFLRKIA 277
           +   +   +N   ++   +R +A
Sbjct: 259 IYIFKKQSENLQKVLITAIRNMA 281


>UniRef50_C3ZRU9 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3ZRU9_BRAFL
          Length = 374

 Score =  196 bits (498), Expect = 8e-49,   Method: Composition-based stats.
 Identities = 68/209 (32%), Positives = 110/209 (52%), Gaps = 11/209 (5%)

Query: 77  VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAG--SLRPEVGAGSLVALK 134
            PV   K  G          +   +R FKL+G         A   +L      G ++ + 
Sbjct: 168 RPVRVFKVMGILSAPLP--QVALPVRVFKLMGILSAPLPQVALPVALPAVFNDGYIMLMT 225

Query: 135 DHINT---MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFV 189
            HI+        P+ G N+DRFG RF ++++AY++E R + + + KE GF   + EGV+V
Sbjct: 226 PHISMPGLAGDNPLKGHNEDRFGPRFPAVSDAYNSELRQMARDIGKELGFESFMQEGVYV 285

Query: 190 SYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK- 248
              GP++ET AE ++++++GGD VGMS VPEVI+ARHC ++V  +S +TNM     D K 
Sbjct: 286 QVGGPSYETIAECKLLRMLGGDAVGMSTVPEVIAARHCGIRVFGMSLVTNMVVMDYDTKG 345

Query: 249 -LSHAQTLAAAELSKQNFINLICGFLRKI 276
            ++H + L       Q+   L+   + ++
Sbjct: 346 TVNHEEVLETGRRRAQDMQKLVSKMIGQL 374



 Score = 88.8 bits (219), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 38/121 (31%), Positives = 53/121 (43%), Gaps = 4/121 (3%)

Query: 15  DIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL 74
           D I T K    P++A I GSGLG LAD +E+  AI Y ++P FP ST  G+     L  +
Sbjct: 16  DFILT-KTKHRPKIAVICGSGLGGLADIVEDQNAIDYSEIPNFPRSTADGYTQSAPLPQV 74

Query: 75  QGVPVVCMKGRGHFYEGRGMTI--MTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
             +PV   K  G            +   +R FKL+G         A  +   V    L+ 
Sbjct: 75  A-LPVRVFKLMGILSAPLPQVALPVALPVRVFKLMGILSAPLPQVALPVALPVRVFKLMG 133

Query: 133 L 133
           +
Sbjct: 134 I 134


>UniRef50_B4CZS2 Methylthioadenosine phosphorylase n=1 Tax=Chthoniobacter flavus
           Ellin428 RepID=B4CZS2_9BACT
          Length = 288

 Score =  196 bits (498), Expect = 9e-49,   Method: Composition-based stats.
 Identities = 59/256 (23%), Positives = 101/256 (39%), Gaps = 14/256 (5%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM-- 82
            P +  I GSGL  + D + N    + E   G P   + G       G L G  V  +  
Sbjct: 3   EPAIGIIGGSGLYQI-DGVTNVTEHTIETPFGAPSDVIVG-------GQLGGRQVYFLPR 54

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            GRGH      +    + +   + L    L C  A GSL+ +     +V      +    
Sbjct: 55  HGRGHRILPHELNHRAN-LYALRSLNVRWLLCVTAVGSLQEQYAPRHIVLPSQFFDRTSQ 113

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAE 201
            P      +       S A+   A  R L+   A+E G P+  G  +V+  GP F T AE
Sbjct: 114 GPAHTFFGNGIAA-HVSFADPTSAPLRQLIVNAARELGLPVHNGGTYVNMDGPAFSTRAE 172

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG-LSDVKLSHAQTLAAAEL 260
               + +G DV+GM+ + E+  AR  ++ V  ++ IT+     + +  ++    +A    
Sbjct: 173 SETHRKLGFDVIGMTNLGEIRLAREAEIAVATMAMITDYDCWKVEEEPVTADAVIAHLHA 232

Query: 261 SKQNFINLICGFLRKI 276
           +      ++   + +I
Sbjct: 233 NADAAKKILARVVPQI 248


>UniRef50_A9GWF6 5'-methyl-5-thioadenosine phosphorylase n=1 Tax=Sorangium
           cellulosum 'So ce 56' RepID=A9GWF6_SORC5
          Length = 295

 Score =  196 bits (498), Expect = 9e-49,   Method: Composition-based stats.
 Identities = 58/255 (22%), Positives = 102/255 (40%), Gaps = 17/255 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQG--VPVVCM--K 83
           +A I GSG+  +   +E+   +S     G P   V       + G ++G    V+ +   
Sbjct: 10  LAIIGGSGVYEMG-WLEDVEEVSVSTPFGLPSDVV-------LRGQVKGGDATVLFLPRH 61

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           GRGH +    +    + I   K+LG   +   +A GSLR ++  G LV +   I+     
Sbjct: 62  GRGHRFSPSTINYRAN-ICALKMLGATHVLSVSAVGSLREDIAPGDLVVVDQFIDFTKRR 120

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEI 202
                ++          A+       + +   A   G  +  G  +V   GP F T AE 
Sbjct: 121 ISTFFDEGLVA--HVPFADPVCPILASAVHDAALATGARVHRGGTYVCIEGPQFSTRAES 178

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG-LSDVKLSHAQTLAAAELS 261
           RM +  G  V+GM+ +PE   AR  +L    ++  T+     +S+  +S    +A    +
Sbjct: 179 RMFRTFGAHVIGMTNLPEAKLAREAELPYATLALTTDFDCWHVSEEAVSVEAVIAVLNRN 238

Query: 262 KQNFINLICGFLRKI 276
                ++     RK+
Sbjct: 239 IGYARDVAKSLARKL 253


>UniRef50_A3TNF6 Methylthioadenosine phosphorylase n=1 Tax=Janibacter sp. HTCC2649
           RepID=A3TNF6_9MICO
          Length = 272

 Score =  194 bits (494), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 67/253 (26%), Positives = 106/253 (41%), Gaps = 14/253 (5%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
              +  I G+G   L D +++A +          V T +G    +  G   G PVV +  
Sbjct: 6   RHPLGIIAGTGFYDL-DALDDARS--------ETVDTAYGPTS-VTQGSWHGQPVVFVTR 55

Query: 85  RGHFYEGRGMTIMTDAI-RTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
            G  +E     +   AI R    LG   +   N  G + P++ AG +V + D ++     
Sbjct: 56  HGAGHEVPPHMVNYRAIVRALADLGVHDVIAVNVTGGIDPDLEAGEIVVIDDFLDFTRQR 115

Query: 144 PMVGLN-DDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAE 201
                + D   G     +  AYD   R  L   A   G  + +G V+V + GP FE+ AE
Sbjct: 116 SATFHDGDGPEGVVHTDMTTAYDPVLRRELLDAASAIGQSVIDGGVYVCFDGPRFESPAE 175

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS-DVKLSHAQTLAAAEL 260
           IR+  + GG V GM+ VPEV  A    L+  A+S + N A G+     ++  +  A  E 
Sbjct: 176 IRLAALAGGTVAGMTGVPEVTLAAEAGLRYAALSLVVNPAAGVRPGEPITMDEISAVLET 235

Query: 261 SKQNFINLICGFL 273
                + +I   +
Sbjct: 236 GAPKVLAVIDELV 248


>UniRef50_C4Q4X0 Methylthioadenosine phosphorylase, putative n=1 Tax=Schistosoma
           mansoni RepID=C4Q4X0_SCHMA
          Length = 314

 Score =  194 bits (493), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 59/273 (21%), Positives = 99/273 (36%), Gaps = 32/273 (11%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           +V  I GSG     +  +           G P  T       LV G +  V  V +   G
Sbjct: 5   KVGIIGGSGFDD-PNLFKKVGVRQVTTPFGKPSDT-------LVEGFVGDVACVVLPRHG 56

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + +   K LGC  +  TNA GSL+ ++  G  V L   ++   G  
Sbjct: 57  KGHLIPPSEVNYRAN-VWALKDLGCTHILATNACGSLQEDLVPGDFVVLNQFMDKTWGRE 115

Query: 145 MVGLN---DDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-----------------T 184
                   D   G     +A  +    R +L + A+ +   +                  
Sbjct: 116 NTFYGSKPDSLKGVLHMPMAEPFCERTRQILIQAARNKSINVYDKKTMDKSACIHPCVHA 175

Query: 185 EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL 244
           EG  V+  GP F T  E  + + +G D+V M++VPEV  AR   L   +++ +T+     
Sbjct: 176 EGSAVTINGPRFSTRCESFIHKAMGLDIVNMTLVPEVSLAREAGLSYASIAIVTDFDCWK 235

Query: 245 SDVK-LSHAQTLAAAELSKQNFINLICGFLRKI 276
           S+ + +     L     S  +   ++   +  I
Sbjct: 236 SEEEHVCVDMVLEQFRKSVVHVREILLEAVALI 268


>UniRef50_C8R2U4 Methylthioadenosine phosphorylase n=1 Tax=Desulfurivibrio
           alkaliphilus AHT2 RepID=C8R2U4_9DELT
          Length = 254

 Score =  193 bits (490), Expect = 7e-48,   Method: Composition-based stats.
 Identities = 67/257 (26%), Positives = 106/257 (41%), Gaps = 16/257 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           V  I GSGL      IENA  ++ +   G P       +  L+ G + G  V  +   G 
Sbjct: 4   VGIIGGSGLEN-PQLIENAREVTVDTPYGPP-------SAPLLRGRIGGREVALLARHGR 55

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H      +    + +   +  GC  L  + A GSLR ++G G LV     I+      +
Sbjct: 56  EHTIPPSQVNNRANLL-ALQEQGCTHLLASAACGSLRQDIGPGELVIPDQLIDFTRFRAV 114

Query: 146 VGLNDDRFG---ERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAE 201
              +    G    R  +LA+ + AE R  L    +    PL +G   ++  GP F T AE
Sbjct: 115 TFHDHFPPGIENARHTALADPFAAEIRKQLLMAGRHLELPLHDGGTMLTIEGPRFSTRAE 174

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDV-KLSHAQTLAAAEL 260
            RM Q+ G D+V M++ PE + A    L    V+ +T+      D   L   + +A    
Sbjct: 175 SRMFQLWGADLVNMTIAPEAVLAAELGLPYAVVAMVTDYDSWKEDEPPLQVPELVAVFRG 234

Query: 261 SKQNFINLICGFLRKIA 277
           + +    L+   L ++A
Sbjct: 235 NLEKLSRLLITVLPRLA 251


>UniRef50_C2KQL7 Possible purine-nucleoside phosphorylase n=2 Tax=Mobiluncus
           mulieris RepID=C2KQL7_9ACTO
          Length = 279

 Score =  192 bits (489), Expect = 9e-48,   Method: Composition-based stats.
 Identities = 68/270 (25%), Positives = 121/270 (44%), Gaps = 21/270 (7%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGL-GALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
             + +I+         V  +LGSGL   + +  +N V +  ++L G  + +  GH  ++V
Sbjct: 25  AAVQLIQERTQRENHDVLVVLGSGLHDTVCNLGKNPVELPLKELLGAKIPSAQGHGTQIV 84

Query: 71  LGHLQG----VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVG 126
              ++     V ++   GR H YEG     +    +   + G +  F TNA G L+P   
Sbjct: 85  SVQIETEAKTVNILVCTGRIHLYEGHTPADLCFVPQVAAMTGIQAAFLTNAGGCLQP-WE 143

Query: 127 AGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG 186
            G ++A++DHIN    +P  G         F  ++  +D++  A ++K A         G
Sbjct: 144 LGDVMAIRDHINFSGASPFTGP-------VFVDISQVWDSDLTAAIKKHASRS------G 190

Query: 187 VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD 246
           V+    GP ++T AE  MM+  G D+VGMS V E I+     ++V  VS  +++    S 
Sbjct: 191 VYAISRGPEYQTLAESIMMRNNGIDMVGMSTVLEAIALHQLGVRVCGVSVTSDLT--FSS 248

Query: 247 VKLSHAQTLAAAELSKQNFINLICGFLRKI 276
              +H++ L A   +     N +   +  +
Sbjct: 249 TPTTHSEVLHAVRSAIPCVQNCLYEVINAL 278


>UniRef50_UPI00016C3D31 inosine guanosine and xanthosine phosphorylase family protein n=2
           Tax=Gemmata obscuriglobus UQM 2246 RepID=UPI00016C3D31
          Length = 261

 Score =  191 bits (486), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 75/226 (33%), Positives = 113/226 (50%), Gaps = 6/226 (2%)

Query: 49  ISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLG 108
           + +  +PG    +VHGH G L +G   GVP + ++GR HFYEG    ++T  +RT   LG
Sbjct: 39  VPFGAVPGLVPPSVHGHGGTLAVGEWGGVPALLVRGRVHFYEGHPWEVVTGTVRTAAELG 98

Query: 109 CELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEY 168
              L  TNAAG + P +  G+L+A++ H+  +      GL       R       Y A  
Sbjct: 99  ARRLVLTNAAGGINPALSPGALMAIRGHLKLLGPAAWRGLAAGDGSVR------PYAARL 152

Query: 169 RALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCD 228
             +++   +  G  L  G++ +  GP++ET AEIR +   G D VGMS   E  +A    
Sbjct: 153 IEVMRAHERAGGRELLAGLYAALTGPSYETPAEIRALAACGADAVGMSTALEAEAAAARG 212

Query: 229 LKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLR 274
           L+V A+S +TN A G+    L HA+ L  A L+      L+   +R
Sbjct: 213 LEVAAISCVTNKAAGIGGTALDHAEVLTNAALAVDRLGALLGALIR 258


>UniRef50_A6GFX4 Purine nucleoside phosphorylase n=1 Tax=Plesiocystis pacifica SIR-1
           RepID=A6GFX4_9DELT
          Length = 278

 Score =  191 bits (485), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 77/273 (28%), Positives = 118/273 (43%), Gaps = 26/273 (9%)

Query: 13  CIDIIKTYKPDFTP-RVAFILGSGLGA-LADQIENAVAISYEK-LP----GFPVSTVHGH 65
           C   ++   P+  P     I GSG+G  L  + E+A+ +S  + +P    G P  +V GH
Sbjct: 14  CEAALRERLPEQGPVDWMIIGGSGIGKPLVAEGEHALGLSIRERIPLAELGLPAPSVAGH 73

Query: 66  AGELVLGHLQG-----VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
             ELV G L       V V    GR H YEG    + +  +     +G   +  T+A G 
Sbjct: 74  GSELVFGELAREGADPVQVCVQTGRIHPYEGHSAALASAPLGAVLSIGARQVLLTSAVGG 133

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           +  ++  G +V+ +D  N    T + G         F   +  YD E RA LQ+      
Sbjct: 134 VNTQLRVGEIVSYRDQFNLFGPTSLRGA-------AFIDCSRLYDPELRARLQQ----LD 182

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
             L E V+    GP +E+ AE+  ++ +G DVVGMS   E I A    +    +  +TN 
Sbjct: 183 GSLREVVYGHARGPQYESPAEVAALRTLGCDVVGMSTTYEAILAAAHGVPTCGLGVVTNA 242

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFL 273
           A       LSH +    +  ++    NL+ G L
Sbjct: 243 A---GAEALSHVEVQEESGKARTRLANLVRGLL 272


>UniRef50_Q87BR7 Probable S-methyl-5'-thioadenosine phosphorylase n=16 Tax=Bacteria
           RepID=MTNP_XYLFT
          Length = 248

 Score =  190 bits (482), Expect = 7e-47,   Method: Composition-based stats.
 Identities = 60/251 (23%), Positives = 97/251 (38%), Gaps = 11/251 (4%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +A I G+G+  L+ Q ++      E L G P       +G + +G L G  V      G 
Sbjct: 6   LAVIGGTGVYTLS-QFDDVQVYEVETLYGRP-------SGPIRVGMLFGQRVAFFARHGE 57

Query: 88  FYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
            +      I   A I   + LG   +   N  G +    G  +LV     I+   G    
Sbjct: 58  EHALPPHKINYRANIAALQQLGVSRVLALNTVGGINEAFGPRTLVCPDQLIDYTWGRVST 117

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRMM 205
              +           + Y    R  L + A++    L E G +    GP  ET AEI  +
Sbjct: 118 FCEEVGSEVLHVDFGHPYSPLLRGCLLRAARDVDVSLVEYGCYGVTQGPRLETIAEIDRL 177

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VKLSHAQTLAAAELSKQN 264
           +  G D+VGM+ +PE   AR   L+   +  ++N A G  D  +++  + L+    +   
Sbjct: 178 RRDGCDLVGMTGMPEAALAREKGLEYACLGIVSNWAAGCGDGAEITMGEILSNVATAFSC 237

Query: 265 FINLICGFLRK 275
              LI    R+
Sbjct: 238 LPELISKVARE 248


>UniRef50_B0DVC8 Predicted protein n=3 Tax=Basidiomycota RepID=B0DVC8_LACBS
          Length = 315

 Score =  189 bits (481), Expect = 8e-47,   Method: Composition-based stats.
 Identities = 58/256 (22%), Positives = 95/256 (37%), Gaps = 19/256 (7%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +  I GSGL  L D +     ++ E   GFP S++       +     G  V  +   G 
Sbjct: 9   IGIIGGSGLYHL-DNLTQITTVNPETPWGFPSSSIT------IAALPSGTRVAFLARHGQ 61

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H      +    + I   K LG   +   +A GSLR E+  GS V     I+   G   
Sbjct: 62  GHVIPPSSVPGRAN-IAALKSLGVRAIIAFSAVGSLREEISPGSFVLPTQIIDRTKGIRP 120

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKV------AKEEGFPLTEG-VFVSYPGPNFET 198
               +           + +  +    L++       A+ +G  L  G   V   GP F T
Sbjct: 121 ASFFEGTSIVAHAMFGDPFSGKLVKWLEERVRKALDAEGKGAKLFTGKCIVCMEGPQFST 180

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG-LSDVKLSHAQTLAA 257
            AE  M +  GGD++ MSV+PE   AR  +L    ++  T+          ++ A     
Sbjct: 181 RAESLMYRQWGGDLINMSVLPEAKLAREAELSYALIATATDYDSWRDQSESVTAADVFKT 240

Query: 258 AELSKQNFINLICGFL 273
            + + +    L+   +
Sbjct: 241 LKGNAET-SRLVAATI 255


>UniRef50_Q1PVD3 Similar to 5'-methylthioadenosine phosphorylase n=1 Tax=Candidatus
           Kuenenia stuttgartiensis RepID=Q1PVD3_9BACT
          Length = 294

 Score =  188 bits (479), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 57/260 (21%), Positives = 102/260 (39%), Gaps = 20/260 (7%)

Query: 28  VAFILGSGLGAL--ADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           +A I GS    L  +  I+        ++     +T +G +  +         ++ +   
Sbjct: 9   LAVIGGSQAYDLLLSGCIKGKR---LGEI-----NTPYGRSQPVYFIRDANAEMLFLSRH 60

Query: 86  GHFYEGRGMTIM--TDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           G    G     +     I   K LG + +   +  G++      G  V + D I+   G 
Sbjct: 61  GEKGYGVTAPFVNYRANIYALKELGAKQIVSWSGPGAMNENYKIGEYVLIDDIIDETHGR 120

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEI 202
                     G  F      +    R  +    K  G  +T +GV+V   GP  ET AEI
Sbjct: 121 ESTFYK--HLGIGFIRQFPVFCPTLRESILHTLKFLGIGITGKGVYVCTQGPRLETPAEI 178

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA---- 258
           R  ++ GGD+VGM++VPEV  A+  ++   ++  +TN AEG++       +         
Sbjct: 179 RKYKLYGGDLVGMTLVPEVFLAKELEMCYASICYVTNYAEGIASRPFKAGELFEGLATDS 238

Query: 259 -ELSKQNFINLICGFLRKIA 277
              + ++ + L    ++KIA
Sbjct: 239 DREAVRSAVALFPQIIKKIA 258


>UniRef50_C6DE56 Methylthioadenosine phosphorylase n=1 Tax=Pectobacterium
           carotovorum subsp. carotovorum PC1 RepID=C6DE56_PECCP
          Length = 301

 Score =  188 bits (479), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 62/261 (23%), Positives = 106/261 (40%), Gaps = 15/261 (5%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           +    PR+  I GSG+ +L+  IE    I+     G P       +G + LG + GVPV 
Sbjct: 5   RTTTPPRIGIICGSGMDSLS-IIEAPERINVTTSFGDP-------SGIITLGEIAGVPVA 56

Query: 81  CMKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
            +   G  H      + +  + I   K LG   +   +A GSL  E   G+ VA+  +I+
Sbjct: 57  IVNRHGIGHRLLPSEINVRAN-IAALKALGVSQVISFSAVGSLVEEAPPGTFVAIDQYID 115

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP-LTEGVFVSYPGPNFE 197
                                       +  +LL     E   P L +G++V   GP+F 
Sbjct: 116 RTYRRVNTFFGSG--VVAHVPFGKPVCTDNHSLLVDALGELSIPHLAKGLYVVMEGPHFS 173

Query: 198 TAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQTLA 256
           T AE    + +GG V+GM+ +PE    R  +L    V+ +T+     +  + ++ A    
Sbjct: 174 TKAESAFHRQMGGTVIGMTAMPEPKLCREAELCYNMVAMVTDYDCWHTSHEAVNAAMVSE 233

Query: 257 AAELSKQNFINLICGFLRKIA 277
               + +   +L+   + K+A
Sbjct: 234 QMADNIKKAESLLSVIVPKLA 254


>UniRef50_Q1H1A2 Methylthioadenosine phosphorylase n=3 Tax=Bacteria
           RepID=Q1H1A2_METFK
          Length = 248

 Score =  188 bits (479), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 56/251 (22%), Positives = 92/251 (36%), Gaps = 14/251 (5%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH-AGELVLGHLQGVPVVCMKGRG 86
           +  I G+GL  LA+       I   ++    V T +G  +G L  G + G  V+ +   G
Sbjct: 2   LGIIGGTGLTKLANL-----KIKRRQI----VRTPYGEPSGPLTYGDICGYEVIFLPRHG 52

Query: 87  HFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
           H +      +   A I      G   +    + G + P +  G +      I+   G   
Sbjct: 53  HGHTIPPHIVNYRANIWALHAEGVRDIVSVASVGGIHPRLDPGVIALPDQIIDYTHGRKN 112

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIRM 204
              +      +       Y    R L  + A      + +G V+    GP  ETAAEI  
Sbjct: 113 TYYDGGDLPVKHIDFTMPYSDRLRNLCLEAATNISESIIDGGVYACVQGPRLETAAEINR 172

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK--LSHAQTLAAAELSK 262
           ++  G  +VGM+ +PE   AR  D+   A+  + N A G       + +         + 
Sbjct: 173 LERDGATMVGMTGMPEAALARELDMHYAAICPVANHAAGRGSSAKGIQYDNMGDVLNKTM 232

Query: 263 QNFINLICGFL 273
           Q   NLI   +
Sbjct: 233 QRVRNLIERVV 243


>UniRef50_B7RUB3 Phosphorylases family 2 n=1 Tax=marine gamma proteobacterium
           HTCC2148 RepID=B7RUB3_9GAMM
          Length = 246

 Score =  187 bits (476), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 62/252 (24%), Positives = 92/252 (36%), Gaps = 12/252 (4%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
            +  I G+G+  L + +E   + + E   G P   V         G L GV V  ++  G
Sbjct: 3   TLGIIGGTGIDQL-EGLEIVDSHAVETPYGDPSRAVE-------EGMLGGVRVFFLQRHG 54

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
                    +    + +   K L    L   NA G +   +  G LV     ++   G  
Sbjct: 55  SPKTIPPHLINYRAN-VWALKSLQVTDLVAINAVGGISAAMRPGRLVIPDQIVDYTWGRA 113

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIR 203
                 +         ++ YD E R  L + A  +       GV     GP  E+AAEIR
Sbjct: 114 HTVDTGEVGTLLHVDFSDPYDHELREALLQCAVAQNIAHEGAGVHGVMQGPRLESAAEIR 173

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
            M   G D+VGM+ +PE   AR   L   ++  + N A GL D  L+ A   A       
Sbjct: 174 RMAGDGCDLVGMTGMPEASLARELGLAYASICMVVNAAAGLDDKPLTLAVMRANLLREAA 233

Query: 264 NFINLICGFLRK 275
               LI   +  
Sbjct: 234 AVRQLIAALVAD 245


>UniRef50_D2V2R7 5'-methylthioadenosine phosphorylase n=1 Tax=Naegleria gruberi
           RepID=D2V2R7_NAEGR
          Length = 299

 Score =  186 bits (474), Expect = 6e-46,   Method: Composition-based stats.
 Identities = 58/259 (22%), Positives = 98/259 (37%), Gaps = 19/259 (7%)

Query: 26  PRV--AFILGSGLGALADQIENAVAI-SYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM 82
           PRV  AFI G+GL   A+ +EN + +  +E   G P S +       V+G + G+ V  +
Sbjct: 10  PRVDLAFIGGTGLSK-AEGLENVITVEPFETPFGKPSSPI-------VIGTINGLTVAFL 61

Query: 83  KGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
              G  H  +   +    + I   K LG   L    A GSL+ E+     V +   I+  
Sbjct: 62  CRHGLSHSVQPTDVPYRAN-IFALKSLGANNLVSFGAVGSLQEELAPKHFVVVDQFIDRT 120

Query: 141 PGTPMVGLNDDRFG-ERFFSLANAYDAEYRALLQKVAKEEGF---PLTEGVFVSYPGPNF 196
                     DR G     S           L+                G +V   GP F
Sbjct: 121 KFRQSENTFYDREGLVAHVSFGEPTCKTLSQLVVDSCSRIETIPKTHATGTYVCMEGPCF 180

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VKLSHAQTL 255
            + AE +M ++ GG ++GM+ + E   AR  ++    V  +T+      +   ++  + +
Sbjct: 181 SSRAESKMYRMWGGSIIGMTCLQEAKLAREAEMAFACVGMVTDYDAWKDEAEPVTVEEVV 240

Query: 256 AAAELSKQNFINLICGFLR 274
                +  N   +I    +
Sbjct: 241 KILHDNGDNARRVIQEVAK 259


>UniRef50_B5EMB0 Methylthioadenosine phosphorylase n=15 Tax=Proteobacteria
           RepID=B5EMB0_ACIF5
          Length = 270

 Score =  185 bits (470), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 59/253 (23%), Positives = 91/253 (35%), Gaps = 14/253 (5%)

Query: 29  AFILGSGLGALAD-QIENAVAISYEKLPGFPVSTVHGH-AGELVLGHLQGVPVVCMKGRG 86
             I GSGL  L + QI +   I           T  G  +G L  G L G  VV +   G
Sbjct: 5   GIIGGSGLTGLKNLQIRHRRVI----------RTPFGETSGPLTFGQLGGQEVVFIARHG 54

Query: 87  HFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
           + +      +   A +     +G   +    A G +   +  G L      I+   G P 
Sbjct: 55  YGHTIPPHRVNYRANVWALHHVGVTHVVAVAAVGGITAAMRPGVLCLPDQLIDYTSGRPS 114

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIRM 204
                          +  Y    R  L + A      + +G  + +  GP  ET AEIR 
Sbjct: 115 TFFEGGESMVVHIDFSEPYCQPLRERLLQAAGSADIVVIDGGTYAATQGPRLETIAEIRR 174

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           ++  GGDVVGM+  PE + AR   L    +S + N A G S   ++            + 
Sbjct: 175 IERDGGDVVGMTGAPEAVLAREIGLCYAPLSLVVNPAAGKSAEPITMEAIDMVMHEGMEK 234

Query: 265 FINLICGFLRKIA 277
              ++   +  +A
Sbjct: 235 VRKVLGNVVPLLA 247


>UniRef50_B5YKP5 S-methyl-5-thioadenosine phosphorylase n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YKP5_THEYD
          Length = 265

 Score =  185 bits (469), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 60/254 (23%), Positives = 109/254 (42%), Gaps = 17/254 (6%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGE-LVLGHLQGVPVVCMKGR 85
           ++  I GSGL   ++  +  + I           T +G       +  +  + V+ ++  
Sbjct: 8   KIGIIGGSGLSE-SEAKKEIITIK----------TPYGEPSCPYEIEKIDDIEVLFLRRH 56

Query: 86  G--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           G  H      +    + I  FK  G E +F   A GSL   +  GS+V     I+   G 
Sbjct: 57  GQKHSIPPHKVNYRAN-IYGFKNFGIERIFGVFATGSLTENIPPGSIVIPNQIIDFTQGM 115

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP-LTEGVFVSYPGPNFETAAEI 202
                 +++           + +E R  L + A++ G   ++   ++   GP  ETAAEI
Sbjct: 116 RANTFYEEK-KVVHIDFTEPFCSEIRHYLLETARKIGINVISHATYICVNGPRLETAAEI 174

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
           +  + IG D++GM+++PE   AR  ++   AV+ + N A G+S   L+  + +   E S 
Sbjct: 175 KFFKNIGADIIGMTIMPEASLAREVEICYAAVAVVANYAAGISKFPLTVKEVIETMEDSL 234

Query: 263 QNFINLICGFLRKI 276
                LI   ++K+
Sbjct: 235 DAVGFLIKETIKKL 248


>UniRef50_A4X3Q9 Methylthioadenosine phosphorylase n=8 Tax=Actinomycetales
           RepID=A4X3Q9_SALTO
          Length = 267

 Score =  184 bits (468), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 55/259 (21%), Positives = 97/259 (37%), Gaps = 20/259 (7%)

Query: 22  PDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV-LGHLQGVPVV 80
           P+    +  I G+GL  L  + E              +ST +G   +L+ +  L    V 
Sbjct: 4   PNLNADIGVIGGTGLYELLGETEEVK-----------ISTPYGAPSDLITVAELNSRQVA 52

Query: 81  CMKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
            +   G  H +    +    + I   + LG   +    A G LRP+  AG+ V     I+
Sbjct: 53  FLPRHGRDHRFPPHRIPYRAN-IWALRSLGVRQILAPCAVGGLRPDFIAGTFVVPDQLID 111

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFET 198
              G      +    G    + A  Y  + R      A+     +  G  V   GP F T
Sbjct: 112 RTSGREQTFCDT---GAVHTTFAEPYCPDGRRAALAAAERVNR-VDGGTMVVIDGPRFST 167

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQTLAA 257
            AE R     GG ++ M+  PE   AR   L   +++ +T++  G+   + ++H + L A
Sbjct: 168 RAESRWHAAAGGTIINMTGQPEAALARELALCYTSIALVTDLDAGVEGSQGVTHDEVLRA 227

Query: 258 AELSKQNFINLICGFLRKI 276
              +      ++   +  +
Sbjct: 228 FAKNVTVLRRVLFDAVAAL 246


>UniRef50_C1SHM5 Purine nucleoside phosphorylase n=1 Tax=Denitrovibrio acetiphilus
           DSM 12809 RepID=C1SHM5_9BACT
          Length = 263

 Score =  183 bits (466), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 54/247 (21%), Positives = 89/247 (36%), Gaps = 14/247 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM--KG 84
           ++  I GSGL  + +  E    I  +   G P  T         +   + +    +   G
Sbjct: 3   KLGIIGGSGLYDI-EGFEYVEEIIMQTEYGDPSDT-------YRVFSYKDMRFYFLNRHG 54

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           R H      +    + I  F  LG E +    A G +      G ++   D I+   G  
Sbjct: 55  RSHSVPPHKVNYRAN-IDGFSRLGIENIVSITATGGINSSYKPGDIIIPDDGIDMTSGRI 113

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIR 203
                  +           +    R +L+  A+         G +V   GP  ET  EI+
Sbjct: 114 QTFYESKQIH--HIDFTEPFCPRLRGILENSAESADVDAAVNGTYVCTNGPRMETKGEIK 171

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
                G D+VGM++ PE   AR  +L    +S ITN A G S  KL+  + +     + +
Sbjct: 172 AFDRWGADLVGMTLFPECSLARERELCYANLSVITNYAAGTSSTKLTADEVVEEMGKATE 231

Query: 264 NFINLIC 270
               ++ 
Sbjct: 232 KLKGIVS 238


>UniRef50_Q09438 Putative S-methyl-5'-thioadenosine phosphorylase n=4 Tax=Metazoa
           RepID=MTAP_CAEEL
          Length = 288

 Score =  183 bits (466), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 49/256 (19%), Positives = 96/256 (37%), Gaps = 15/256 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           +V  I GSGL    + + + V ++ +   G P       + ++V G + GV  V +   G
Sbjct: 3   KVGIIGGSGLED-PNILLDPVTVAVDTPYGKP-------SDDVVEGTINGVECVLLARHG 54

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + +      G +++  + A GSL+  V  G L+      +   G  
Sbjct: 55  RKHDIMPGNVNFRAN-LWALYSRGVDVIIASTACGSLQENVEPGHLLFPDSVFDRTTGRQ 113

Query: 145 MVGLN---DDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAA 200
               +   D   G         Y+ + R +L   A+         G  V   GP F T A
Sbjct: 114 STFFDGSYDQAPGVCHIQAHPTYNEKLRQVLISTAERCQLVHHRTGFGVCIEGPRFSTKA 173

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAEL 260
           E  + +  G  +V M+++PE I A+   +     + +T+      +  ++ +  +     
Sbjct: 174 ESMVFKSWGASLVNMTMMPECILAKELGIPYATTALVTDYDCWKEEDHVTASSVMKVFAA 233

Query: 261 SKQNFINLICGFLRKI 276
           + +    L    + +I
Sbjct: 234 NVEKAKTLFVEAVGEI 249


>UniRef50_C5TP90 Methylthioadenosine phosphorylase n=5 Tax=Neisseria
           RepID=C5TP90_NEIFL
          Length = 238

 Score =  183 bits (466), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 56/242 (23%), Positives = 94/242 (38%), Gaps = 17/242 (7%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHG-HAGELVLGHLQGVPVVCMKGRG 86
           +A I GSGL  L +       I+  K+    V T +G  +  ++ G L  + +V +   G
Sbjct: 2   LAIIGGSGLTKLPEL-----EITERKI----VRTPYGLTSSPILFGRLGRLDIVFLARHG 52

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + I     LG E +   ++   + P+   GSLV   D I+   G  
Sbjct: 53  FSHTIAPHEINYRAN-IWALHSLGVENIIAISSVVGINPDFENGSLVLPDDLIDYTYGRK 111

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIR 203
                            N Y  E R  L  + K    P+ +  V+    GP   T AEI 
Sbjct: 112 DTFFEGQECPVVHTDFFNPYCDELRQELLNITKAHNVPIYDSAVYGCLQGPRRPTRAEIA 171

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVV---AVSAITNMAEGLSDVKLSHAQTLAAAEL 260
             +  G DV+GM+ +PE + AR   +      +VS+I     G+     +   ++   ++
Sbjct: 172 RYRRDGVDVLGMTGMPEAVLARELKMAYAHFCSVSSIDCFDSGVGTEGCNEQTSMTMTKI 231

Query: 261 SK 262
            +
Sbjct: 232 RQ 233


>UniRef50_A4AL37 5'-methylthioadenosine phosphorylase n=3 Tax=Actinobacteria (class)
           RepID=A4AL37_9ACTN
          Length = 267

 Score =  183 bits (464), Expect = 7e-45,   Method: Composition-based stats.
 Identities = 59/251 (23%), Positives = 102/251 (40%), Gaps = 17/251 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +A I GSGL +L          + +      + T +G    +  G L G  V  +   G 
Sbjct: 8   LAVIGGSGLYSL---------FAPDSAKHQRIETPYG-PTTVSFGELSGRMVAFIPRHGS 57

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H      +    + I     +G   +  T A G++ P+   GSLV    +I+   G   
Sbjct: 58  GHSVAPHLINYRAN-IWALGSIGVRAIVSTAAVGAVHPDFPVGSLVLPDQYIDRTQGRAA 116

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMM 205
                DR   +  + ++ +     AL      +E   + +G  V   GP F T AE +  
Sbjct: 117 TFY--DRESVQHLASSDPFCPSLHALAVAATGDE--AIAQGTVVVIQGPRFSTRAESQWF 172

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNF 265
           + +GG +V M++ PEV  A   ++  + V+ IT+    +SD +LS     A  + ++   
Sbjct: 173 RSMGGHLVNMTLYPEVPLASELNIGTINVAYITDNDATVSDEQLSAELVFARLKEAQPRI 232

Query: 266 INLICGFLRKI 276
           I +I   +  I
Sbjct: 233 IRVIEKIIATI 243


>UniRef50_O28486 Methylthioadenosine phosphorylase (MtaP) n=1 Tax=Archaeoglobus
           fulgidus RepID=O28486_ARCFU
          Length = 243

 Score =  181 bits (461), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 57/252 (22%), Positives = 106/252 (42%), Gaps = 21/252 (8%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +  I G+        +E  V    E+     + T +G A E+ +G + G+ V  ++  G 
Sbjct: 2   IGIIGGT------HILEIKVLKDVEET---RIETPYGTA-EIDVGRVDGIDVAIIQRHGK 51

Query: 88  FYEGRGMTIM-TDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
             +     I         K LG + +    + G+LR E    SL+   D+I+   G  + 
Sbjct: 52  RKDKPPHRINHAANFYALKSLGVKYVIGMGSVGALREEYSLPSLIIPHDYIDFFSGVTI- 110

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG--FPLTEGVFVSYPGPNFETAAEIRM 204
             ND         +   +D   R +L +VA++      + +GV+    GP  ET AEI M
Sbjct: 111 -YNDS-----LVHVTPGFDEYLREVLVEVARKISSFPVIDKGVYFQTRGPRLETKAEIAM 164

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           ++    D VGM+   E   AR   L    V  + N A G+ +  + + + +  A+ + + 
Sbjct: 165 IKSF-ADCVGMTAGSEATIARELGLSYAIVCTMDNYAHGIKNQSIDYREIVEKAKENARE 223

Query: 265 FINLICGFLRKI 276
            + ++   ++K+
Sbjct: 224 CLKIVEEAVKKV 235


>UniRef50_B8KGW0 Purine phosphorylase, family 2 n=1 Tax=gamma proteobacterium NOR5-3
           RepID=B8KGW0_9GAMM
          Length = 249

 Score =  181 bits (459), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 53/251 (21%), Positives = 92/251 (36%), Gaps = 11/251 (4%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +  I G+GL AL   +E   + + +   G P   +         G   G  +  +   G 
Sbjct: 3   LGLIGGTGLNALP-GLEVVASHAVDTPFGQPSMAIE-------EGVYAGHKLFFLHRHGG 54

Query: 88  FYEGRGMTIM--TDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
             +     ++     +   + LG   +   NA G++   +  G LV     I+   G   
Sbjct: 55  RAQPIPPHLVNYRANVWALRELGVTRILAANAVGAISAGMAPGKLVVPHQLIDYTWGREH 114

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRM 204
              +              YD   R+ +   A+  G P ++  V     GP  ETAAE++ 
Sbjct: 115 SFDDGSSGELLHVDFTQPYDGVLRSEIISAAESAGVPHSDTAVLGVVQGPRLETAAEVQR 174

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
               G D++GM+ +PE   AR   +   A+  + N A G+    +S              
Sbjct: 175 FAADGCDLLGMTGMPEAALARELGIPYAAICMVVNAAAGVGAEPISMEAIRNTLLEETAL 234

Query: 265 FINLICGFLRK 275
           F  L+  F+R+
Sbjct: 235 FGALVGAFVRR 245


>UniRef50_A2VPA1 Purine nucleoside phosphorylase deoD n=1 Tax=Mycobacterium
           tuberculosis C RepID=A2VPA1_MYCTU
          Length = 241

 Score =  180 bits (458), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 66/186 (35%), Positives = 94/186 (50%), Gaps = 13/186 (6%)

Query: 92  RGMTIMTDAIRTFKLL--GCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLN 149
           R  T  T  IR  + +  G  L         LR ++  G  V + DH+N    +P+VG  
Sbjct: 66  RDTTCATSCIRFGRPVRQGRRLWCSPTPPVGLRADLQVGQPVLISDHLNLTARSPLVGGE 125

Query: 150 DDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIG 209
                  F  L +AY    R L    A++    L EGV+   PGP++ET AEIRM+Q +G
Sbjct: 126 -------FVDLTDAYSPRLREL----ARQSDPQLAEGVYAGLPGPHYETPAEIRMLQTLG 174

Query: 210 GDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLI 269
            D+VGMS V E I+AR    +V+ VS +TN+A G++   LSHA+ LAA   S      L+
Sbjct: 175 ADLVGMSTVHETIAARAAGAEVLGVSLVTNLAAGITGEPLSHAEVLAAGAASATRMGALL 234

Query: 270 CGFLRK 275
              + +
Sbjct: 235 ADVIAR 240


>UniRef50_A0YHC5 Methylthioadenosine phosphorylase n=1 Tax=marine gamma
           proteobacterium HTCC2143 RepID=A0YHC5_9GAMM
          Length = 241

 Score =  179 bits (455), Expect = 8e-44,   Method: Composition-based stats.
 Identities = 53/249 (21%), Positives = 94/249 (37%), Gaps = 14/249 (5%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG-HLQGVPVVCMKGRG 86
           +  I G+GL +          +           T +G     ++G  ++G+PV  +   G
Sbjct: 2   IGIIGGTGLSSFHQGRSVGDRL-----------TPYGETSAAIIGSEIEGIPVCFLARHG 50

Query: 87  HFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
             +      +   A I  FK LG   L   NA G +  E+ AGSLV     ++   G   
Sbjct: 51  DPHRIPPHKVNYRANIWAFKELGVSKLVAVNAVGGITSEMPAGSLVIPDQIVDYTYGRDH 110

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIRM 204
              + +         +  + +  R L+   A      + +G       GP  E+AAEI  
Sbjct: 111 TFYDGNNNELEHIDFSFPFASGLRQLIVAAAAASNINIIDGATLGVTQGPRLESAAEINR 170

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           M+  G ++VGM+ +PE   AR   +   ++  + N A G     ++  Q     +    +
Sbjct: 171 MESDGCELVGMTAMPEAALARELSIDYASICLVVNPAAGRGHSVITMDQINDVIQFGMTD 230

Query: 265 FINLICGFL 273
              L+   +
Sbjct: 231 VRRLLMAAI 239


>UniRef50_A7BPC6 Purine phosphorylase, family 2 n=2 Tax=Gammaproteobacteria
           RepID=A7BPC6_9GAMM
          Length = 181

 Score =  179 bits (454), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 48/182 (26%), Positives = 76/182 (41%), Gaps = 2/182 (1%)

Query: 94  MTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRF 153
           M    + I + K LG + +    A G + PE+    LV     I+           D+  
Sbjct: 1   MNYRAN-IGSIKALGIKTVIAVAAVGGIHPEMRPKDLVIPHQMIDYTYSREQTFFADEFN 59

Query: 154 GERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIRMMQIIGGDV 212
                     Y  E R  L K A+   F +  +GV+ +  GP  ETAAEI  M+  G D+
Sbjct: 60  HVTHIDFTQPYCDELREQLLKAAESFDFKVHSQGVYGATQGPRLETAAEINRMEREGCDI 119

Query: 213 VGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGF 272
           VGM+ +PE   AR  +L     + + N A G    +++  +  A  +   +N   L+   
Sbjct: 120 VGMTGMPEAALARELELCYATCAVVANPAAGRGSAQITMTEIEATLKQGIENVRQLLGVV 179

Query: 273 LR 274
           +R
Sbjct: 180 IR 181


>UniRef50_C1C2B0 S-methyl-5-thioadenosine phosphorylase n=2 Tax=Caligus
           RepID=C1C2B0_9MAXI
          Length = 283

 Score =  179 bits (454), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 45/224 (20%), Positives = 86/224 (38%), Gaps = 7/224 (3%)

Query: 61  TVHGHAGE-LVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAA 118
           T +G   + LV G + G+ V+ +    H        +   A I   +  G   +    A 
Sbjct: 39  TPYGEPSDALVSGKIDGIDVIFLSRHSHDKRFNPSEVNYKANIDALRQAGVTHILAATAC 98

Query: 119 GSLRPEVGAGSLVALKDHINTMPGTPMVGL---NDDRFGERFFSLANAYDAEYRALLQKV 175
            SL+ +      V L   I+             N D     F  +  ++    R ++ +V
Sbjct: 99  ESLQDDKKPEEFVILDSFIDRTTKRKQTFYDLSNPDDHSCAFIPMHPSFCERSRKIVYEV 158

Query: 176 AKEEGFPLT-EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAV 234
             + G  +  +G  V+  GP F + AE  + +    DV+ M+ VPEV+ A+   +  V+V
Sbjct: 159 GSKMGLKVHPKGTIVTIEGPRFSSKAESLVFKSWNADVINMTTVPEVVLAKEAGISYVSV 218

Query: 235 SAITNMAEG-LSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           + +T+      S+  ++    +     +  N   L    +  +A
Sbjct: 219 AMVTDYDCWRESEESVTAQAVIEVMVKNSANVKALSRNCISALA 262


>UniRef50_C1YKP8 Inosine guanosine and xanthosine phosphorylase family protein n=1
           Tax=Nocardiopsis dassonvillei subsp. dassonvillei DSM
           43111 RepID=C1YKP8_NOCDA
          Length = 274

 Score =  178 bits (452), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 68/247 (27%), Positives = 112/247 (45%), Gaps = 12/247 (4%)

Query: 30  FILGSGLGALADQIENA-VAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHF 88
            +LGSG     D + +  + +    LPGF      GH+G++    +    V+   GR H 
Sbjct: 38  VVLGSGWAGAVDTLGSYDIELDATDLPGFHEPAAEGHSGKIRSMWVGDKRVIVFMGRVHL 97

Query: 89  YEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGL 148
           YEGR    +  A+RT    G      T AAGSLR +   G  V ++DHIN    +P+VG 
Sbjct: 98  YEGRDPLEVVHAVRTGVAAGARTAVLTGAAGSLRTDFATGQPVVVRDHINLTARSPLVGP 157

Query: 149 NDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQII 208
           +       F  L++AY    R  +Q+        + EGV+V   GP  +T AE++++   
Sbjct: 158 S-------FVDLSSAYSPRLRRAVQEA----DASVPEGVYVCTTGPQTQTPAELKVLHQA 206

Query: 209 GGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINL 268
           G D+VG S+  E ++A     +V+ ++ ++N A G         + L       +    L
Sbjct: 207 GADLVGHSIALEAVAAVEAGAEVLGLAVVSNDAVGAVFEPFEAERALDVVTQRARRLGEL 266

Query: 269 ICGFLRK 275
           +   + +
Sbjct: 267 LNRVIGQ 273


>UniRef50_Q5C0P1 SJCHGC05230 protein (Fragment) n=1 Tax=Schistosoma japonicum
           RepID=Q5C0P1_SCHJA
          Length = 186

 Score =  176 bits (447), Expect = 6e-43,   Method: Composition-based stats.
 Identities = 57/144 (39%), Positives = 77/144 (53%), Gaps = 3/144 (2%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
                  P V  I GSGLG LAD I++   I Y+ +P FP +++ GH+G LV G + G  
Sbjct: 42  QKLTCIVPEVGIICGSGLGKLADGIKDKKIIPYKDIPNFPQTSIPGHSGNLVFGTISGRN 101

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           V+ M+GR H YEG     +   IR  K+LG ++L  +NAAG L   +  G  V LKDHI 
Sbjct: 102 VIVMQGRFHMYEGYNKDEIALPIRVMKILGVKILMVSNAAGGLNRSLKCGDFVILKDHIY 161

Query: 139 TMP---GTPMVGLNDDRFGERFFS 159
                    +VG N + FG RF +
Sbjct: 162 FPGLGLNNILVGPNQEEFGPRFPA 185


>UniRef50_Q9RIJ1 Purine nucleoside phosphorylase homolog (Fragment) n=1
           Tax=Streptococcus pyogenes RepID=Q9RIJ1_STRPY
          Length = 149

 Score =  176 bits (446), Expect = 9e-43,   Method: Composition-based stats.
 Identities = 61/148 (41%), Positives = 86/148 (58%), Gaps = 1/148 (0%)

Query: 128 GSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGV 187
           G+L+A+ DHIN     P++G N D FG RF  +++AY   YR    +V  +    L +GV
Sbjct: 3   GTLMAITDHINMTGNRPLIGENLDEFGPRFPDMSDAYTKVYRDKAHEVHDKMNIKLEDGV 62

Query: 188 FVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDV 247
           ++   GP +ET  EIR  Q +G D VGMS+VPEVI A H  LKV+ +SAITN A G    
Sbjct: 63  YLGLTGPTYETPGEIRASQGLGEDPVGMSLVPEVIVAAHSGLKVLGISAITNFAAGFQSE 122

Query: 248 KLSHAQTLAAAELSKQNFINLICGFLRK 275
            LSH + +   +  K++F  L+   L +
Sbjct: 123 -LSHEEVVEVTQHIKEDFTGLVKAILAE 149


>UniRef50_Q2BRI1 Methylthioadenosine phosphorylase n=1 Tax=Neptuniibacter
           caesariensis RepID=Q2BRI1_9GAMM
          Length = 283

 Score =  175 bits (444), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 54/254 (21%), Positives = 95/254 (37%), Gaps = 16/254 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +A I G+G+  L + +E       E   G P       +  +  G +    ++ +   G 
Sbjct: 2   LAIIGGTGIYQL-EGLEVMGEHELETPFGSP-------SAAITQGKMADQDLLFLPRHGR 53

Query: 88  FYE--GRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            +E     +    + I   K LG   +   +A GSL+ E+  G L     + + + G   
Sbjct: 54  RHELLPSEVNYRAN-IWALKKLGATQVIGLSAVGSLQEEIAPGDLSLPDQYFDFVKGNRE 112

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRM 204
                +       S A          L+K A+  G  +     +    GP   T AE   
Sbjct: 113 KTFFGNGLAA-HVSTAEPTSKCLADGLEKAAESVGQKVHRNKTYACVDGPRLGTRAESFF 171

Query: 205 MQ-IIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD--VKLSHAQTLAAAELS 261
           ++   G D+VGM+ VPEV  AR   L    ++  T+    L D    +S  Q +A    S
Sbjct: 172 LRGAAGCDLVGMTNVPEVFLAREAQLCYCTIAIATDYDCWLDDPAQHVSVEQVIARYGAS 231

Query: 262 KQNFINLICGFLRK 275
            +    ++  ++ +
Sbjct: 232 LEKAKQVLTAYITQ 245


>UniRef50_B5ICA6 Phosphorylases family 2 n=2 Tax=Aciduliprofundum boonei T469
           RepID=B5ICA6_9EURY
          Length = 224

 Score =  175 bits (443), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 55/245 (22%), Positives = 97/245 (39%), Gaps = 26/245 (10%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +  I GSGL    + IE    I         + T +G     +     G     +   G+
Sbjct: 2   IGIIGGSGLYDGIEGIEGKEKI---------IRTEYGDVKVFI-----GDNFAFVSRHGN 47

Query: 88  FYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG 147
             +          I  F+ L  + +   +  GSL+  +  GS +   + ++      +  
Sbjct: 48  PPKPPHRVNYHANIMAFRELNVKNIVAISTVGSLKDNIKPGSFLLPSNLLDFT--NRVWT 105

Query: 148 LNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQI 207
            +D+       ++   +  E R    K+ ++   PL  G + +  GP FETAAE  M++I
Sbjct: 106 YHDNE--PYHVNMYEPFCKELR---VKINEKLSIPL-GGTYATMKGPQFETAAEANMLRI 159

Query: 208 IGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFIN 267
           +G D+VGM+V PE   A+  +L    +  + N  +G    K SH + L   +   +    
Sbjct: 160 LGADIVGMTVAPEAKLAKELNLCYQPICIVVNYVDG----KTSHKENLKVMKELNEQLKK 215

Query: 268 LICGF 272
           LI   
Sbjct: 216 LIQEL 220


>UniRef50_C5C002 Methylthioadenosine phosphorylase n=37 Tax=Actinomycetales
           RepID=C5C002_BEUC1
          Length = 301

 Score =  171 bits (435), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 55/253 (21%), Positives = 89/253 (35%), Gaps = 16/253 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +  I GSGL  L   + +   +      G P           VLG L G  V  +   G 
Sbjct: 19  IGVIGGSGLYEL---LASPAPVDVTTPFGTPSEAP-------VLGELGGRQVAFLPRHGA 68

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H +    +    + +   + LG   +    A G+L P++  G++V     I+   G   
Sbjct: 69  DHRFPPHRVPYRAN-LWALRALGVRQVVTVGAVGALVPDLARGAVVVPDQIIDLTSGREH 127

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIRM 204
             + D          A+ Y    RA            + +G   V   GP F T AE R 
Sbjct: 128 T-VFDGVGTVVHVPFADPYCPRGRAAALSALGGRALDVRDGGTLVVINGPRFSTRAESRR 186

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL-SDVKLSHAQTLAAAELSKQ 263
               GG VVGM+ +PE   AR   +    ++ +T+   G+     ++HA  L        
Sbjct: 187 NVAAGGTVVGMTGMPEAALARELAMCCTNLALVTDADAGVDGGESVTHAAVLEEFARHLA 246

Query: 264 NFINLICGFLRKI 276
                +   +  +
Sbjct: 247 VLRASLTDVVTAL 259


>UniRef50_Q5KPU2 Glutamate biosynthesis-related protein, putative n=2
           Tax=Agaricomycotina RepID=Q5KPU2_CRYNE
          Length = 303

 Score =  171 bits (433), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 62/256 (24%), Positives = 96/256 (37%), Gaps = 13/256 (5%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           V  I GSGL  L D +     +  E   G P S ++     L  G L  V  +   G  H
Sbjct: 9   VGCIGGSGLYHL-DNLTFVKTVHIETPWGKPSSPINI--SSLPSGAL--VAFISRHGSHH 63

Query: 88  FYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG 147
                 +    + I   K +GCE +   +A GSLR E+  G  +     I+   G     
Sbjct: 64  SITPSEVPCRAN-IAALKHIGCEAIIAFSAVGSLREEIAPGHFIIPDQIIDRTKGIREDT 122

Query: 148 LNDDRFGERFFSLANAYDAEYRA----LLQKVAKEEG-FPLTEG-VFVSYPGPNFETAAE 201
                           +  +  A     ++K+ KE G   L  G   V   GP F T AE
Sbjct: 123 FFRGEGLVVHSMFGEPFSQKLNAFVAPRVEKILKETGDVVLHTGKTVVCMEGPAFSTRAE 182

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VKLSHAQTLAAAEL 260
             M +  GGD++ MSV+PE   AR  +L    +   T+     +    ++  + +     
Sbjct: 183 SLMYRQWGGDIINMSVIPEAKLAREAELDYTLICTSTDFDAWRTGYDPVTVEEVVKVLHT 242

Query: 261 SKQNFINLICGFLRKI 276
           +  N   +  G L+ +
Sbjct: 243 NAGNSRAVAAGILQDV 258


>UniRef50_Q09816 Uncharacterized protein C16C9.02c n=49 Tax=cellular organisms
           RepID=YAC2_SCHPO
          Length = 307

 Score =  171 bits (433), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 50/261 (19%), Positives = 91/261 (34%), Gaps = 22/261 (8%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +  I GSG   L    +   +++     G+P S +       +     G  +  +   G 
Sbjct: 10  LGVIGGSGFYDLP-GFDIVESVNPITPWGYPASPIS------IARTTSGFLIAFLARHGV 62

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM-PGTP 144
            H Y    +    + I   K LG   +   +A GSLR ++     V     I+      P
Sbjct: 63  GHIYTPTEVPSRAN-IAALKSLGVLAIVSFSAVGSLREDIPPEDFVLPTQIIDRTLCARP 121

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE--GFPLT---EG---VFVSYPGPNF 196
                         S  + +D +   +L         G  L    +G     V   GP F
Sbjct: 122 NTFFESGCVA--HVSFGDPFDQDLYEILSSCGSNLKNGSKLHTKRKGDDLTVVCMEGPAF 179

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG-LSDVKLSHAQTL 255
            T AE  + +  G  ++ MSV+PE   AR  ++    V   T+     +++  ++    +
Sbjct: 180 STRAESNLYRSWGASIINMSVIPEAKLAREAEIAYQMVCMATDYDCWRMNEEPVTVETVM 239

Query: 256 AAAELSKQNFINLICGFLRKI 276
                +K N    +   ++K+
Sbjct: 240 EHISNNKDNAKIFLLEAVKKL 260


>UniRef50_Q07938 Multicopy enhancer of UAS2 n=12 Tax=Saccharomycetaceae
           RepID=MEU1_YEAST
          Length = 337

 Score =  171 bits (433), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 59/269 (21%), Positives = 99/269 (36%), Gaps = 27/269 (10%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV-----LGHLQGVPVVC 81
            +  I G+GL  L D +E    +        P+ T  G     V     +G      V  
Sbjct: 34  DLGIIGGTGLYNL-DCLEPIALLP-------PMVTPWGTTSSPVTISQFVGTNSHFHVAF 85

Query: 82  MKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINT 139
           +   G  H Y    +    + +   K L C+ +   +A GSL+P +     V  +  I+ 
Sbjct: 86  IARHGINHEYPPTKVPFRAN-MAALKNLNCKAVLSFSAVGSLQPHIKPRDFVLPQQIIDR 144

Query: 140 MPGTPMVGLNDDR-------FGERFFSLANAYDAEYRALLQKVAKEEGFPLT---EGVFV 189
             G       +D        FG+ F      Y  +++  +     EE   L    +   V
Sbjct: 145 TKGIRHSSYFNDEGLVGHVGFGQPFSQKFAEYIYQFKNEITNPESEEPCHLHYDKDMTVV 204

Query: 190 SYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VK 248
              GP F T AE +M ++ GG V+ MSV+PE   AR C+L    +   T+      +   
Sbjct: 205 CMEGPQFSTRAESKMYRMFGGHVINMSVIPEAKLARECELPYQMICMSTDYDAWRDEAEP 264

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKIA 277
           ++    +     + +N   L    +  +A
Sbjct: 265 VTVETVIGNLTNNGRNANILASKIIVSMA 293


>UniRef50_B8P408 Predicted protein n=2 Tax=Agaricomycetes RepID=B8P408_POSPM
          Length = 329

 Score =  169 bits (429), Expect = 9e-41,   Method: Composition-based stats.
 Identities = 58/277 (20%), Positives = 100/277 (36%), Gaps = 36/277 (12%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +  I GSGL  L D +     ++ E   GFP S +   A         G  V  +   G 
Sbjct: 16  IGVIGGSGLYHL-DNLTFIKHVNPETPWGFPSSPITICALP------SGTRVAFLARHGT 68

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H      +    + I   K LG   +   +A GSLR ++  G +V     I+   G   
Sbjct: 69  GHSIAPSAVPARAN-IAALKALGVRAVLAFSAVGSLREDIRPGDVVLPAQIIDRTKGVRP 127

Query: 146 VGLNDDRFGERFFSLANAYDAEYRA---------LLQKVAK---EEGFP------LTEGV 187
               +        +  + + A             L ++ A+   E G P        +  
Sbjct: 128 ASFFEGTGVVAHAAFGDPFAARLVRWLEGRVRAVLAEEAARVQRETGRPDAGPRVHADKC 187

Query: 188 FVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDL-------KVVAVSAITNM 240
            V   GP F T AE +M +  GGD++ MSV+PE   AR  +L           ++  T+ 
Sbjct: 188 VVCMEGPQFSTRAESQMYRAWGGDIINMSVLPEAKLAREAELLPPPSLSVYALIATATDY 247

Query: 241 AEGL-SDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
                 +  ++ A+     + + +   ++    L ++
Sbjct: 248 DSWRPHEDAVTAAEVFKTLQENARISRHVAATVLEEL 284


>UniRef50_Q1CZV1 Phosphorylase, family 2 n=5 Tax=Myxococcaceae RepID=Q1CZV1_MYXXD
          Length = 295

 Score =  169 bits (428), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 61/253 (24%), Positives = 89/253 (35%), Gaps = 15/253 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPV--VCMKG 84
           RV  I   GL           +   E   G        HAG +V   L GV V  V   G
Sbjct: 4   RVGIIGSPGLAQALGIPGKGESHILETPFGP-------HAGPIVTTELDGVSVAYVARHG 56

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
            GH Y         + +   K+LG   +  T   GSLR  +    L      I+     P
Sbjct: 57  TGHVYNATRAPYRAN-MYALKVLGVTHVLATGTVGSLREHIHPLHLALPDQVIDRTYRRP 115

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIR 203
               +D         L N +    R +L+      G  +  E  +V   GP+  T AE  
Sbjct: 116 CTFYDDVAV---HVDLGNPFCGTLRQVLEHARDPLGPTVHAEATYVCIEGPSLSTRAESM 172

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQTLAAAELSK 262
           + +  GGD+VGM+ +PE   AR  +L    V+  T+            H   LA    ++
Sbjct: 173 LYRTWGGDLVGMTGMPEARLAREAELHYAMVALPTDYDSWQPRAPGQEHDDLLAQVSHNR 232

Query: 263 QNFINLICGFLRK 275
           +         +R+
Sbjct: 233 KAVTASGAALIRR 245


>UniRef50_A2QWR2 Contig An11c0240, complete genome n=24 Tax=Leotiomyceta
           RepID=A2QWR2_ASPNC
          Length = 311

 Score =  169 bits (428), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 49/264 (18%), Positives = 92/264 (34%), Gaps = 23/264 (8%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVH------GHAGELVLGHLQGVPVV 80
           R+A I G+GL  L        +++     G P S +        H  + V        + 
Sbjct: 13  RIAVIGGTGLRELP-GFTQVASLNVATPWGNPSSPITILHHKCSHNNQTVA-------IA 64

Query: 81  CMKGRGHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINT 139
            +   G  ++     +   A I   + +G   +   +A GSL+ E+     V     I+ 
Sbjct: 65  FLSRHGLHHQIAPHEVPARANIAALRSIGVRTIIAFSAVGSLQEEIKPRDFVVPDQVIDR 124

Query: 140 MPG-TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE---GFPLTE-GVFVSYPGP 194
             G  P                 + +D     +++         G  L + G  +   GP
Sbjct: 125 TKGIRPFTFFEGG--VVAHVPFGDPFDEGVAKVVRACGHSLEGEGVVLHDRGTLICMEGP 182

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG-LSDVKLSHAQ 253
            F T AE ++ +  GG V+ MS +PE   AR  ++    +   T+      S   ++   
Sbjct: 183 QFSTRAESKLYRSWGGSVINMSCLPEAKLAREAEIAYQMICMSTDYDCWHESTADVTVEM 242

Query: 254 TLAAAELSKQNFINLICGFLRKIA 277
            +   + +  N    +   L ++A
Sbjct: 243 VMGNMKANAVNAKRFVTAVLDELA 266


>UniRef50_C9ZU87 Methylthioadenosine phosphorylase, putative n=8
           Tax=Trypanosomatidae RepID=C9ZU87_TRYBG
          Length = 309

 Score =  168 bits (427), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 53/264 (20%), Positives = 96/264 (36%), Gaps = 24/264 (9%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +  I GSG   L + ++N    +     G P       +G + +  + GV    +   G+
Sbjct: 13  IGVIGGSGTYNL-NAMQNVKKYTIPTPYGMP-------SGSISVATVSGVLCAFIPRHGY 64

Query: 88  FYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
            +E     +   A I   KLLG + L   NA GSL  E   G +V +   I+   G    
Sbjct: 65  SHEFTPDEVNYRANIYALKLLGVKYLIGVNAVGSLDAEYQPGDMVLVDQLIDRTTGRRTT 124

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKE------------EGFPLTEG-VFVSYPG 193
              +          A    A +R L      +            + + L  G   V+  G
Sbjct: 125 FFGEGIVA--HVDYAYPLSANFRKLAHDTLTKAMGKLTTAVSGGKPWKLHNGATLVTMSG 182

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQ 253
           P F T AE  + + + G ++GM+   E   AR  ++  + V+A+T+M        +    
Sbjct: 183 PQFSTRAESLINKSLNGHLIGMTTSTESKLAREAEMAYLVVAAVTDMDAWSDAPHVDAES 242

Query: 254 TLAAAELSKQNFINLICGFLRKIA 277
                  + +    ++   +  ++
Sbjct: 243 VRKVMAANVEKVQLIVVELIAAVS 266


>UniRef50_Q11FN7 Methylthioadenosine phosphorylase n=1 Tax=Chelativorans sp. BNC1
           RepID=Q11FN7_MESSB
          Length = 276

 Score =  168 bits (425), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 51/191 (26%), Positives = 80/191 (41%), Gaps = 4/191 (2%)

Query: 59  VSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNA 117
           VST  G A  +++G + G         G         I   A +     LG E +   NA
Sbjct: 26  VSTPWGDAT-ILMGQIGGRDAAVNLRYGEKLTTPSHKINYQANLFALHELGVESIISQNA 84

Query: 118 AGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVA- 176
            GS+ P +  G +V   D ++          ++     R     + +    R  L + A 
Sbjct: 85  IGSVNPAIRPGDIVISDDFLDKTKSRAQSLFDESECWVR-VDFTDPFCPRLRTNLIEAAN 143

Query: 177 KEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSA 236
           +     +  G FV   GP FET AEIR   + GGD+VG  +VPEVI AR  ++   +++ 
Sbjct: 144 RHSNRVIHRGTFVCTEGPRFETPAEIRAYAMEGGDIVGTPLVPEVIFARELEMCFASIAP 203

Query: 237 ITNMAEGLSDV 247
           + N   G++  
Sbjct: 204 VINFGAGMAPA 214


>UniRef50_A0B8I0 Methylthioadenosine phosphorylase n=1 Tax=Methanosaeta thermophila
           PT RepID=A0B8I0_METTP
          Length = 245

 Score =  167 bits (424), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 54/219 (24%), Positives = 88/219 (40%), Gaps = 12/219 (5%)

Query: 59  VSTVHGHAGELVLGHLQGVPVVCMKGRGHFY-EGRGMTIMTDAIRTFKLLGCELLFCTNA 117
           ++T +G+    +   + G  VV +   G  +     +      I   +  G   +   N 
Sbjct: 21  IATPYGNV-RAISSRISGRDVVFISRHGDDHLPPYRVNYRAI-ICAAESTGAGRIIAINT 78

Query: 118 AGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAK 177
            GS+      GS V   D I            D         ++  Y  E R +L +  +
Sbjct: 79  VGSMIS--PPGSFVIPNDFIEFTKFRVPTFYEDRAV---HVDMSEPYCPEIRKVLMESCR 133

Query: 178 EEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAI 237
            EG    EGV+V   GP+FET A+I+M++  G DVVGM+  PEV+ AR   L   ++   
Sbjct: 134 AEGHEPYEGVYVCTEGPHFETHAQIKMLRSFG-DVVGMTGYPEVVLARERGLCYASICLA 192

Query: 238 TNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           TN A    + +    Q ++    S  +   +I   +  I
Sbjct: 193 TNKA---GEGQFDLRQIVSVERKSMSDLARIIERAVSMI 228


>UniRef50_Q0CL04 Purine nucleoside phosphorylase n=1 Tax=Aspergillus terreus NIH2624
           RepID=Q0CL04_ASPTN
          Length = 205

 Score =  167 bits (424), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 74/196 (37%), Positives = 94/196 (47%), Gaps = 20/196 (10%)

Query: 13  CIDIIKTYKPD--FTPRVAFILGSGLGALADQIENA--VAISYEKLPGFPVSTVHGHAGE 68
            +  +K   P    +PRVA + GSGLG LAD I +       Y  +P FP  TV GHAG+
Sbjct: 17  AVQSLKDRLPAELQSPRVAIVCGSGLGGLADSIRDHPRAEYDYGSIPHFPKLTVPGHAGK 76

Query: 69  LVLGHLQ-GVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGA 127
           LV G L   +PVV M GR H+YEG  +  +T  IR FKLLG E +      GS+      
Sbjct: 77  LVFGFLGEDIPVVLMVGRAHYYEGHSIHQVTFPIRVFKLLGVETVVFYR--GSM-----T 129

Query: 128 GSLVALKDHI---NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE-----E 179
                +  HI         P+ G ND+ FG RF  L++AYD E R  + K  K       
Sbjct: 130 KWFTDIAKHIFLSGLAGNHPLRGPNDEEFGPRFPPLSDAYDLELRRHVHKAWKTVVDPLS 189

Query: 180 GFPLTEGVFVSYPGPN 195
              L EGV+    GP 
Sbjct: 190 KRRLHEGVYAYVGGPR 205


>UniRef50_C3Y9W3 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3Y9W3_BRAFL
          Length = 239

 Score =  166 bits (420), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 53/257 (20%), Positives = 89/257 (34%), Gaps = 52/257 (20%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I GSGL    D ++N      +   G P       +  L+LG + GV  V +    
Sbjct: 3   QIGIIGGSGLDN-PDILDNRREKHVDTPYGKP-------SDALILGDVGGVECVLLAR-- 52

Query: 87  HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
                                                ++  G +V L   I+        
Sbjct: 53  ------------------------------------EDIHPGDMVILDQFIDRTTKRATT 76

Query: 147 GLNDDR---FGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEI 202
             + +     G     +   +    R +L  V KE      E G  V+  GP F + AE 
Sbjct: 77  FYDGNPGSPLGVCHLPMDTPFCPHTRKILIDVCKELEIRHHESGTMVTIEGPRFSSRAES 136

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD--VKLSHAQTLAAAEL 260
           +M ++ GGDV+ M+ VPEV  A+   +   AV+  T+      D    +S    L   + 
Sbjct: 137 KMFRMWGGDVINMTTVPEVALAKEAGMCYAAVAMATDYDCWRDDPGHHVSVEAVLKVFKG 196

Query: 261 SKQNFINLICGFLRKIA 277
           + +  + +    + KIA
Sbjct: 197 NAEKGVRIFKSAIPKIA 213


>UniRef50_A7BDZ0 Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus
           ATCC 17982 RepID=A7BDZ0_9ACTO
          Length = 265

 Score =  163 bits (413), Expect = 5e-39,   Method: Composition-based stats.
 Identities = 72/274 (26%), Positives = 113/274 (41%), Gaps = 20/274 (7%)

Query: 2   SQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIE--NAVAISYEKLPGFPV 59
            Q       +    I+ +      P     LGSGL    D+     A  +S   +PG   
Sbjct: 8   PQALLDDEAVAGARILTSLAG--RPDALVALGSGLSEALDEAWGAPAATVSLGDIPGVVA 65

Query: 60  STVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAG 119
               GH GEL      G  V+   GR H YEG G+  +    R     G      TNA G
Sbjct: 66  PVADGHGGELRAYEACGGVVLVATGRTHLYEGLGVRPVAALARAAVAAGISRAVLTNANG 125

Query: 120 SLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE 179
            L+P    G ++A+ DH+N    +P  G         F  ++  +DA+    L+ V +  
Sbjct: 126 CLKP-WNLGDVMAITDHVNLSGASPFDGP-------LFLDVSAVWDAQMTQALRGVCQ-- 175

Query: 180 GFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
                EG +    GP ++T AE R++  +G D VGMS V E I+     ++V  +S +++
Sbjct: 176 ----REGTYAILRGPEYQTMAETRILSGLGVDCVGMSTVMEAITLHALGVRVAGMSVVSD 231

Query: 240 MAEGLSDVKLSHAQTLAAAELSKQNFINLICGFL 273
           ++   +D        + AA  ++Q  +  I   L
Sbjct: 232 LS--FADGPTDPTAVVEAASAARQTVVAGIEAAL 263


>UniRef50_Q0SDK3 Probable S-methyl-5-thioadenosine phosphorylase n=2 Tax=Rhodococcus
           RepID=Q0SDK3_RHOSR
          Length = 260

 Score =  163 bits (412), Expect = 7e-39,   Method: Composition-based stats.
 Identities = 58/261 (22%), Positives = 98/261 (37%), Gaps = 21/261 (8%)

Query: 22  PDFTPRVAFILGS-GLGALADQIENAVAISYEKLPGFPVSTVHGHAGE-LVLGHLQGVPV 79
           PD  P V  +LG+ G   L D  E              + T +G   + +VLG   G  +
Sbjct: 2   PDTQPTVG-VLGTWGYHGLLDDAEQVD-----------IDTPYGPTSDSIVLGSSGGRRL 49

Query: 80  VCMKGRGHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
             +   G         I   A I     LG   +     +GSLRP +G GS+V     ++
Sbjct: 50  AYLTRTGRHRNIPPHRINARANIWALHSLGVRTILAPTPSGSLRPAIGVGSVVVPDQLVD 109

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFE 197
               T     +DD       S A+ + A  R  +    +  G+ + +G V V+  GP F 
Sbjct: 110 RTGRTDDTFHDDD----VHISFADPFCAHGRRAVVSTLRRNGWVVNDGGVMVAIRGPRFS 165

Query: 198 TAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAE-GLSDVKLSHAQTLA 256
           T AE R     G D++ M+  PE   AR   +    ++ +T+      +   ++      
Sbjct: 166 TRAESRWYAAQGWDLISMTPYPEAALARELGMSYTCIALVTDHDVISDTPWPVTQDLVRE 225

Query: 257 AAELSKQNFINLICGFLRKIA 277
             + + +     +     ++A
Sbjct: 226 GLDANTKRLREALLQVAIELA 246


>UniRef50_B3PJG7 Methylthioadenosine phosphorylase n=1 Tax=Cellvibrio japonicus
           Ueda107 RepID=B3PJG7_CELJU
          Length = 308

 Score =  161 bits (407), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 59/258 (22%), Positives = 94/258 (36%), Gaps = 28/258 (10%)

Query: 10  PLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGEL 69
           PL     +    P    R+A I G+ L  +    +            F + T  G + ++
Sbjct: 21  PLAASAAVPADIP--RARIAVIGGTFLNDIFFYRDVVKK-------EFTLETTLGTSPKI 71

Query: 70  VLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGS 129
                 G+P   +   G     +              LG E       AG++ P +    
Sbjct: 72  YYAEWDGIPFYYVHNHGDGQWQQTWV-------ALYDLGVEEAIGGATAGAINPSMKVYD 124

Query: 130 LVALKDHINTMPGTPMVGLND---DRFGERFFSLANAYDAEYRALLQKVAKE-------- 178
            +   D I+     P+        D        L  A D + R +L +  ++        
Sbjct: 125 YIIPHDLIDMNIDRPLGFPKQVYRDPNAIPLPRLTPAMDTDLRQILLEQTRKAIKADKRY 184

Query: 179 EGFPLT-EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAI 237
           + F +  +GV V   G  FET AEI+M    GGD+V MSV  E++ AR   +    V  I
Sbjct: 185 KSFKVHDKGVIVQARGGRFETVAEIKMFGQWGGDLVTMSVGTEIVYARQLGINYATVVVI 244

Query: 238 TNMAEGLSDVKLSHAQTL 255
           +N AEG+ +   S  + L
Sbjct: 245 SNPAEGVGEWDFSLMKEL 262


>UniRef50_B8NP67 5'-methylthioadenosine phosphorylase (Meu1), putative n=1
           Tax=Aspergillus flavus NRRL3357 RepID=B8NP67_ASPFN
          Length = 365

 Score =  160 bits (406), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 51/282 (18%), Positives = 95/282 (33%), Gaps = 36/282 (12%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVH-GHAGELVLGHLQGVPVVCMKGR 85
           R+A I G+GL  L        +++     G P S +   H       + Q V V  +   
Sbjct: 44  RIAVIGGTGLRELP-GFTQVASLNISTPWGTPSSPITILHHQCSH--NKQTVAVAFLSRH 100

Query: 86  GHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG-T 143
           G  ++     +   A I   + +G   +   +A GSL+ E+     V     I+   G  
Sbjct: 101 GLHHQIAPHEVPARANIAALRSIGVRTIIAFSAVGSLQEEIKPRDFVIPDQVIDRTKGIR 160

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE---GFPLTE-GVFVSY-------- 191
           P                 + +D     +++         G  L + G  V          
Sbjct: 161 PFTFFEGG--VVAHVPFGDPFDEGVAKVVRACGHSLEGEGVVLHDRGTLVCMGMLFAQSD 218

Query: 192 ---------------PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSA 236
                           GP F T AE ++ +  GG V+ MS +PE   AR  ++    +  
Sbjct: 219 RSNRYQYNRLLTSFPEGPQFSTRAESKLYRSWGGSVINMSCLPEAKLAREAEIAYQMICM 278

Query: 237 ITNMAEG-LSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
            T+      +   ++    +   + + +N  + +   L ++A
Sbjct: 279 STDYDCWHEATADVTVEMVMGNMKANAENAKHFVTAVLDELA 320


>UniRef50_A0L8V4 Methylthioadenosine phosphorylase n=1 Tax=Magnetococcus sp. MC-1
           RepID=A0L8V4_MAGSM
          Length = 241

 Score =  156 bits (396), Expect = 5e-37,   Method: Composition-based stats.
 Identities = 61/256 (23%), Positives = 106/256 (41%), Gaps = 28/256 (10%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++A I G+ L      +E+ +   +     +P++T  G         L+   +V ++  G
Sbjct: 6   KIAVIGGTSL------LESHL---FSGAKEYPIATPFGKVTL-----LEKQGLVFLQRHG 51

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H+     +    + +   K  G   L    + GS++ E   G+ +   D +       
Sbjct: 52  MDHYTPPHLINHKAN-LAGLKEYGITHLLAIGSVGSMKLEHPPGTFLIPDDFL---GLDV 107

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVA---KEEGFPLTEGVFVSYPGPNFETAAE 201
                +D  G +       +D  +R  +       +  G P+  GV+    GP FET AE
Sbjct: 108 CPTFFEDARGHQVPG----FDPAWRQQILAAWPPSESFGAPVDGGVYWQTRGPRFETQAE 163

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELS 261
           IRM Q    DVVGM+V  E I AR  DL   A+  + N A G+SD  L++A        +
Sbjct: 164 IRMYQAF-TDVVGMTVASECILARELDLAYAAICIVDNYANGISDEPLTYAAFKQKVAEN 222

Query: 262 KQNFINLICGFLRKIA 277
           +    +L+   L +++
Sbjct: 223 EARLGSLLHILLERLS 238


>UniRef50_UPI0000164ED7 purine nucleoside phosphorylase n=1 Tax=Halobacterium sp. NRC-1
           RepID=UPI0000164ED7
          Length = 206

 Score =  155 bits (393), Expect = 1e-36,   Method: Composition-based stats.
 Identities = 54/209 (25%), Positives = 78/209 (37%), Gaps = 19/209 (9%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAG-ELVLGHLQ--GVPVVCMKG 84
           + FI GSG+           A+    +    VST +G     + +G     G  V  +  
Sbjct: 2   IGFIGGSGIYD---------ALPLNDVRETAVSTPYGDPSAPVTIGEFGDTGTEVAFLPR 52

Query: 85  RG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            G  H      +    + I  FK LG E +  +NA GSLR E+   +LV      +    
Sbjct: 53  HGSDHQRSPTNLPYRAN-IYAFKQLGVERILASNAVGSLRDELSPQTLVIPDQIFDRTNH 111

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE--GVFVSYPGPNFETAA 200
                  D          A+ Y       L   A +     T+  G +V   GP + T A
Sbjct: 112 RDATFFGDG--VVVHQPFADPYCPHMVEHLHDAATDATDADTQQGGTYVCIEGPQYSTRA 169

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDL 229
           E    +  G D+VGM+ +PE   ARH  L
Sbjct: 170 ESEFYKAQGWDLVGMTAIPEAKLARHSSL 198


>UniRef50_D1J9Q0 Putative uncharacterized protein n=2 Tax=uncultured archaeon
           RepID=D1J9Q0_9ARCH
          Length = 245

 Score =  155 bits (391), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 62/254 (24%), Positives = 99/254 (38%), Gaps = 27/254 (10%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I G+ L      +E A     E        T +G A  LV   L     V +   G
Sbjct: 14  KLGVIGGTSLFG-TKLLEGAKEKEVE--------TKYGRAYLLVTDEL-----VFIPRHG 59

Query: 87  HFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
                    I   A + +FKLL  E +    + GSL+  +   SLV   D+I        
Sbjct: 60  KATNIPPHRINYRANLASFKLLDVEKIIGATSVGSLKRAITPRSLVVPHDYICL------ 113

Query: 146 VGLNDDRFGE-RFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIR 203
              N     +     +    D   R+ + +VA E    + E GV+     P  ET AEIR
Sbjct: 114 --YNIPTVYDDEIVHVTPGLDDGLRSTIIEVANELDMEIFEQGVYFQTVAPRLETKAEIR 171

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQTLAAAELSK 262
            M+    DVVGM++  E   A    L+   +S + N A G+ + + L + + +  A  S+
Sbjct: 172 FMRNY-ADVVGMNMASEATLAMELGLRYADISTVDNYAHGIIEEEVLDYKKIVEDASKSR 230

Query: 263 QNFINLICGFLRKI 276
            +   ++   +  I
Sbjct: 231 VDLEKVLIKLIEVI 244


>UniRef50_Q2LVG5 Phosphorylase family 2 protein n=1 Tax=Syntrophus aciditrophicus SB
           RepID=Q2LVG5_SYNAS
          Length = 240

 Score =  152 bits (385), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 51/202 (25%), Positives = 89/202 (44%), Gaps = 14/202 (6%)

Query: 79  VVCMKGRG----HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALK 134
           VV +   G     +     +    + ++    L    +   N+AGSL  +   G+++   
Sbjct: 42  VVFLPRHGTDPNRYILPHQINHRAN-MKALCELSVREIVAINSAGSLHRKWKPGTIMVPD 100

Query: 135 DHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP-LTEGVFVSYPG 193
           D I       + G++  +       L    D + R  L + A+EEG   +  GV+   PG
Sbjct: 101 DFIMLTG---IPGIHQTQAAH----LTPQLDLKVRHYLLEAAREEGVNVIDRGVYWQMPG 153

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQ 253
           P  ET AEIRM+     D+VGM++  E ++A+   L   A+ +I N   GL +  L+  +
Sbjct: 154 PRLETRAEIRMISRF-ADLVGMTLASEAVTAQELGLAYGALCSIDNYGNGLVEKLLTVEE 212

Query: 254 TLAAAELSKQNFINLICGFLRK 275
            +A A  + +  I +   +L K
Sbjct: 213 IVAHARENARVMIGIATRYLEK 234


>UniRef50_Q2FR33 Methylthioadenosine phosphorylase n=1 Tax=Methanospirillum hungatei
           JF-1 RepID=Q2FR33_METHJ
          Length = 224

 Score =  151 bits (383), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 51/251 (20%), Positives = 98/251 (39%), Gaps = 31/251 (12%)

Query: 28  VAFILGSGLGALADQIENAVAISY--EKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           +  I G+ L            + Y   +   F   T +G +        +G     +   
Sbjct: 2   LGIIGGTSL------------LDYQGSEFTKFEQHTPYGTSELF-----KGEGFFLLLRH 44

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            +      +   +  I   KL G + +    + GSL+ ++  GS V   D I   P   +
Sbjct: 45  QNRCAPHIIPYRSH-IAALKLAGADRIIALGSTGSLQEDIPPGSRVIPDDFICLTPVPTI 103

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMM 205
           +    D     F       DA+ R LL K++ E    +  G ++   GP  E+ AEI  M
Sbjct: 104 MNHTIDHVNPEF-------DADLRTLLMKLSPE---AIQRGTYIQTRGPRLESKAEISWM 153

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNF 265
           +    D+VGM++  E+  A    L   A+  + N A G+ D ++++   +     +++  
Sbjct: 154 KRF-ADIVGMTIGSELTVAAELGLPFAAICTVDNYANGVCDAQITYESIIRTVRENQEKA 212

Query: 266 INLICGFLRKI 276
           ++L+   +  +
Sbjct: 213 LDLLGRIINSV 223


>UniRef50_A9B0Q9 Purine phosphorylase family 2 n=1 Tax=Herpetosiphon aurantiacus
           ATCC 23779 RepID=A9B0Q9_HERA2
          Length = 253

 Score =  150 bits (380), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 51/225 (22%), Positives = 88/225 (39%), Gaps = 11/225 (4%)

Query: 28  VAFILGSGLGALADQIENAVAI-SYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           +  + G+G   L  ++E  +   +Y+ +      T +G AG +         +      G
Sbjct: 2   ILLLGGTGTYFL--ELEATLGAGNYQTI-----ETPYGTAGSIYQPERFAGKIGLASRHG 54

Query: 87  HFYEGRGMTIM--TDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
                     +     I   K LG + +   N  G++   +    LV L   +N     P
Sbjct: 55  WGRLDVSPPFVNSRANIWAAKELGYQNILSWNGVGAINQLLQVHDLVVLNHVLNGTKTRP 114

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE-EGFPLTEGVFVSYPGPNFETAAEIR 203
           +    D      +      +D    ++L + A+  +      G +    GP  ETAAEIR
Sbjct: 115 INFAGDLPNASAWQIAQRVFDPASASVLYQQARRYQARSFDCGTYACSEGPRLETAAEIR 174

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK 248
                G DVVGM++VPEV+ A    +K  +++ +TN A G+    
Sbjct: 175 AWANFGADVVGMTLVPEVLLAYELGIKFASLAYVTNFATGVEPST 219


>UniRef50_B1ZY09 Purine phosphorylase family 2 n=2 Tax=Opitutaceae
           RepID=B1ZY09_OPITP
          Length = 232

 Score =  148 bits (373), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 61/253 (24%), Positives = 106/253 (41%), Gaps = 26/253 (10%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           +VAFI  SG   +   + +A  +          +T +G       G       V +   G
Sbjct: 2   KVAFI--SGTSIVNSDLFSAWEVK-------TTTTPYGQVTYKTKG-----DFVLINRHG 47

Query: 87  HFYE--GRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           + +      +    + IR    LG + +   N+ GSL+ ++  G+ V+  D++    G P
Sbjct: 48  YAFPLPPHSINYRAN-IRALADLGFKDILSLNSVGSLKRDLPPGTFVSCSDYVGLQQG-P 105

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIR 203
           M   + +  G          +     L++K+A E  F +  G V+V + GP FET AEIR
Sbjct: 106 MTFFDQELKG----GAPGIANNLIPLLIEKLAPE--FKIHPGKVYVQFRGPRFETKAEIR 159

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
           ++Q  G DVVGM+   E        L+  +++ I N A GL   ++  A+     + ++ 
Sbjct: 160 IVQSWG-DVVGMTAAHEADLCSELGLRYNSLALIDNYANGLEGTEIDFAKFKDLVKDNQA 218

Query: 264 NFINLICGFLRKI 276
               L    L  +
Sbjct: 219 KVNRLFTRILEIL 231


>UniRef50_C0W926 Purine-nucleoside phosphorylase n=1 Tax=Actinomyces urogenitalis
           DSM 15434 RepID=C0W926_9ACTO
          Length = 286

 Score =  147 bits (372), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 62/276 (22%), Positives = 102/276 (36%), Gaps = 25/276 (9%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGL-GALADQIENAVAISYEKLPGFPVSTVHGHAGEL 69
           L     I          +  +LGSG  GAL    E    +    LPG       GH   L
Sbjct: 25  LDAAHQIARRTGADHHDLLVVLGSGADGALEGWGEPEATLPLSDLPGVLAPAAPGHRDLL 84

Query: 70  VLGHL--------QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSL 121
                        +G+ V+   GR H YEG G   +    R     G       NA G L
Sbjct: 85  ASYRRTLPGDDGDRGLRVLVAYGRTHLYEGHGSAPVVALARAAAAAGVRAAVLVNANGCL 144

Query: 122 RPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF 181
           R +   G ++ + DH+N    +P  G         F  +   +D     +L+K       
Sbjct: 145 R-DWRLGEVMTITDHLNLTGSSPFDGT-------VFVDVREVWDRRLAQVLRK------R 190

Query: 182 PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA 241
              EG + +  GP ++T AE R +   G D VGMS V E I+     ++V  +S +++++
Sbjct: 191 TEREGTYAALRGPEYQTMAETRWLAGGGADAVGMSTVLEAIALHQLGVRVAGMSVVSDLS 250

Query: 242 EGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
              +       + +     +     + +   + ++A
Sbjct: 251 --FAAEATDPEEVVRLVRGAHATLADGVDAVVAELA 284


>UniRef50_Q7TP15 Cc1-6 n=9 Tax=Coelomata RepID=Q7TP15_RAT
          Length = 391

 Score =  147 bits (371), Expect = 5e-34,   Method: Composition-based stats.
 Identities = 50/302 (16%), Positives = 98/302 (32%), Gaps = 60/302 (19%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I G+GL    + +E       +   G P       +  L+LG ++ V  V +    
Sbjct: 48  KIGIIGGTGLDD-PEILEGRTEKYVDTPFGKP-------SDALILGKIKNVDCVLLASMY 99

Query: 87  --------------------HFYEGRG-------MTIMTD---AIRTFKLLGCELLFCTN 116
                               H                +      +R    + CE  F  +
Sbjct: 100 VLDRMCEFLLLPFCVQLNSLHEIPPGSSCHTSYLFAFVARWERRVRWLARVLCERAFVPS 159

Query: 117 AAGSLRPEVGAGSLVALKD--------------------HINTMPGTPMVGLNDDRFGER 156
           +A +            +                        +  P T   G +    G  
Sbjct: 160 SASTSVQWKETKHSKEITQRSKASRFSTTVQQQAIREECQTSLRPQTFYDGSHCSARGVC 219

Query: 157 FFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIRMMQIIGGDVVGM 215
              +A  +  + R +L ++AK+ G     +G  V+  GP F + AE  + +  G DV+ M
Sbjct: 220 HIPMAEPFCPKTREVLIEMAKKLGLRCHSKGTIVTIEGPRFSSRAESFIFRTWGADVINM 279

Query: 216 SVVPEVISARHCDLKVVAVSAITNMAEGLS-DVKLSHAQTLAAAELSKQNFINLICGFLR 274
           + VPEV+ A+   L   +++  T+       +  +S    L   + +     +L+   + 
Sbjct: 280 TTVPEVVLAKEAGLCYASIAMATDYDCWKEHEEAVSVDGVLKTMKENANKAKSLLLTTIP 339

Query: 275 KI 276
           +I
Sbjct: 340 QI 341


>UniRef50_B0TI52 Purine nucleoside phosphorylase n=8 Tax=Clostridia
           RepID=B0TI52_HELMI
          Length = 304

 Score =  146 bits (369), Expect = 7e-34,   Method: Composition-based stats.
 Identities = 55/272 (20%), Positives = 94/272 (34%), Gaps = 15/272 (5%)

Query: 7   SHNPLFCIDIIKTYKPDFTPRVAFILGSGLGAL--ADQIENAVAISYEKLPGFPVSTVHG 64
           S  P+  + ++ +      P  A I GS   +L   + +        E  PG+   T  G
Sbjct: 11  SQMPMEVMAMLSSASIPAAP-FAIIGGSSTNSLRFPEALNVPGLTVLETYPGW--ETPFG 67

Query: 65  HAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPE 124
            +   V   L+G   +     G     +           F+  G + +      G++   
Sbjct: 68  PSPAFVYFELKGRRALTCVMHGWRPGVKRADASRQIFWVFQQAGVKQILSEGGVGAINEL 127

Query: 125 VGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE---GF 181
           +    LV   D+I+          + D        +   +    R      ++     G 
Sbjct: 128 LRPRDLVIPHDYIDFSMR-----KDVDLGTPTLCIMRQPFCPLLRRAFIDASEALPGKGR 182

Query: 182 PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA 241
                 +V   G +FE+ AE+R  ++ GGDV+G SV PEV  AR        +  + N A
Sbjct: 183 VFDRSNYVVTDGRHFESPAEVRFFRMAGGDVIGQSVAPEVYLAREIGACYARLELVVNYA 242

Query: 242 EGLSDVKLSHAQTLAAA-ELSKQNFINLICGF 272
           EG+     SH +      E S+     L+   
Sbjct: 243 EGVITDW-SHQELKDIFYEESEPAGRRLLMAL 273


>UniRef50_A2SSB6 Methylthioadenosine phosphorylase n=2 Tax=Methanomicrobiales
           RepID=A2SSB6_METLZ
          Length = 223

 Score =  145 bits (365), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 55/253 (21%), Positives = 94/253 (37%), Gaps = 34/253 (13%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL--GHLQGVPVVCMKGR 85
           +  I G+ L  L  ++     I      G    +V  H G +V    H    P   +  R
Sbjct: 2   LGIIGGTAL--LQARLPPLEKIRVSTPFG----SVQAHVGRIVFISRHQNDTPPHRVNHR 55

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H             +   K+LG + L    + GS+  ++  GS+V   D  +     P 
Sbjct: 56  AH-------------LAAMKILGVDKLIVIGSTGSMHDDLPPGSIVIPDDSFSP-WDIPS 101

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMM 205
           +  ND       + +  + +   R  L ++  E       G +    GP FET AEI   
Sbjct: 102 LHDND------IYHIPPSINPGLREELVRIVPEA----KPGTYFQTLGPRFETRAEIACF 151

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKL-SHAQTLAAAELSKQN 264
                DVVGM+   E+  A    +   A+  + N A G+       + + +A A  + + 
Sbjct: 152 AGD-TDVVGMTAASELTLANELGIPCAALCTVDNYANGIGGASAPEYDEIVAIARRNGER 210

Query: 265 FINLICGFLRKIA 277
             ++I   + K+A
Sbjct: 211 ITDIITKIVEKLA 223


>UniRef50_UPI0000D5796F PREDICTED: similar to purine nucleoside phosphorylase, partial n=1
           Tax=Tribolium castaneum RepID=UPI0000D5796F
          Length = 153

 Score =  144 bits (364), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 49/129 (37%), Positives = 73/129 (56%), Gaps = 4/129 (3%)

Query: 153 FGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNFETAAEIRMMQIIGG 210
           FG RF  +  AY+ E     +KVA+E G    + EG +    GPNFET AE+RM++++G 
Sbjct: 20  FGPRFPPMNKAYNRELIDQGKKVARELGMGGMVHEGTYTCLGGPNFETVAELRMLKMLGA 79

Query: 211 DVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD--VKLSHAQTLAAAELSKQNFINL 268
           D VGMS V EVI+ARHCD+ V+A S ITN+     +   K +H + +   ++ +      
Sbjct: 80  DAVGMSTVHEVITARHCDMTVLAFSLITNICITDYECHDKPNHEEVMDVGKMRQDTLKLF 139

Query: 269 ICGFLRKIA 277
           +   +  IA
Sbjct: 140 VKKLVEYIA 148


>UniRef50_Q67R93 Methylthioadenosine phosphorylase n=1 Tax=Symbiobacterium
           thermophilum RepID=Q67R93_SYMTH
          Length = 265

 Score =  144 bits (363), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 47/207 (22%), Positives = 78/207 (37%), Gaps = 22/207 (10%)

Query: 59  VSTVHGHAGELVLGHLQGVPVVCMKGRGH----FYEGRGMTIMTDAIRTFKLLGCELLFC 114
           V T  G AG   +  + G PV  +   G           +    + +   + LG   +  
Sbjct: 26  VETPFGPAGPFRIFAVAGRPVAFLSRHGGEGRLGVTPPFINYRAN-VWAARALGARRVLS 84

Query: 115 TNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG---LNDDRFGERFFSLANA-------- 163
            N+AGS+   +  GSL  + D I+     P        D    +                
Sbjct: 85  WNSAGSMVRALPPGSLAVVSDLIDWTRRRPDSFGAAARDPAVRDTVVRHPAPPAGHATGP 144

Query: 164 -----YDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSV 217
                +D + RA L + A   G       V+ +  G   ET AEI ++   G ++VGM++
Sbjct: 145 AYAGLFDPDLRARLVQAAAACGHRAAPRAVYAATEGARLETRAEIALLAQAGAELVGMTL 204

Query: 218 VPEVISARHCDLKVVAVSAITNMAEGL 244
            PEV  AR   +   ++  ++N A G+
Sbjct: 205 APEVFLARELGMAYGSICWVSNYATGV 231


>UniRef50_Q2RHE2 Purine phosphorylase, family 2 n=1 Tax=Moorella thermoacetica ATCC
           39073 RepID=Q2RHE2_MOOTA
          Length = 283

 Score =  143 bits (362), Expect = 5e-33,   Method: Composition-based stats.
 Identities = 52/262 (19%), Positives = 95/262 (36%), Gaps = 16/262 (6%)

Query: 23  DFTPRVAFILGSGLGAL--ADQIENA-VAISYEKLPGFPVSTVHGHAGELVLGHLQGVPV 79
                + FI GSG  +L   D + +    +   ++     +T  G +  L L      P 
Sbjct: 5   KIQADIGFIGGSGTFSLNFPDALRDPGTEVLAREV---VFTTPWGPSAPLTLFTTGDPPR 61

Query: 80  VCMKGRGH-FYEGRGMTIMTDAI-RTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHI 137
             +  + H    G      +  +   F       +      GS+   +    +V + D+I
Sbjct: 62  RVLAAKMHGRIPGVSWGESSQRLFHAFMQANVRKIIAEGGVGSINHLLDLRDIVVVTDYI 121

Query: 138 NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE--EGFPLTEGVFVSYPGPN 195
           +       VGL +         +           L + A+E   G     GV++   G +
Sbjct: 122 DFSLRRD-VGLQEGYLSI----MRRPICPSLHRTLVETARESPLGRVFDRGVYLVTDGRH 176

Query: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL 255
           FE+AAE+ + +  G DVVG ++ PEV  AR        +  + N  EG+      H +  
Sbjct: 177 FESAAEVSLFRQWGADVVGQTLCPEVYLAREMGACYAGIYLVVNYGEGVV-KPWEHRELK 235

Query: 256 AAAELSKQNFINLICGFLRKIA 277
                +  +F  +I   L +++
Sbjct: 236 ELFFEAAPDFGRIILKALGRVS 257


>UniRef50_C9KQI5 Phosphorylase, family 2 n=1 Tax=Mitsuokella multacida DSM 20544
           RepID=C9KQI5_9FIRM
          Length = 289

 Score =  136 bits (342), Expect = 9e-31,   Method: Composition-based stats.
 Identities = 49/253 (19%), Positives = 84/253 (33%), Gaps = 13/253 (5%)

Query: 29  AFILGSGL--GALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           A + GSG         + +      E    F   T +G +  + L  +    V+ ++  G
Sbjct: 18  AVVGGSGTLSSDFPRNLPDEDVKILEDNLYF--ETPYGKSPSMRLFCVGEKHVLTVRMHG 75

Query: 87  HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
                            F+  G + +      G++   +     +   D+++        
Sbjct: 76  WRSGVTRADASRQVFWVFREAGVKRIISEGGVGTVNKLLDLRDFIIPDDYLDLSVR---- 131

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKE--EGFPLTEGVFVSYPGPNFETAAEIRM 204
             +    G     + +A   E R  L K  K+   G   T G +    G +FE+ AE+ M
Sbjct: 132 -KDVMLDGRYLLVMRDALCPEMREALIKATKKRFTGRVFTRGTYAVTDGRHFESPAEVAM 190

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           M     D+VG S+ PEV  AR        +    N  EG+     SH             
Sbjct: 191 MNGH-ADIVGQSIAPEVYLAREIGACYAGLYFTVNYGEGIRKAW-SHQDMADIFYDDAPM 248

Query: 265 FINLICGFLRKIA 277
              +I   +R +A
Sbjct: 249 IGEIILETIRTVA 261


>UniRef50_UPI0000E4A236 PREDICTED: similar to GTP-binding protein, partial n=3
           Tax=Strongylocentrotus purpuratus RepID=UPI0000E4A236
          Length = 690

 Score =  136 bits (342), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 44/122 (36%), Positives = 71/122 (58%), Gaps = 6/122 (4%)

Query: 160 LANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSV 217
           +   YD + R    KVA+E+       +GV++   GP++ET AE R ++ +GGDVVGMS 
Sbjct: 1   MNKVYDEKLRNSALKVAEEQRIAPFTRQGVYLMVGGPSYETPAEARYLRALGGDVVGMST 60

Query: 218 VPEVISARHCDLKVVAVSAITN---MAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLR 274
           VPEV++ARHC ++ + +S IT+   M  G +   ++H   L  A+      I+L+ G + 
Sbjct: 61  VPEVLAARHCGMRALGLSLITDIVTMDYGAAGA-INHDDFLETAKWRAATMIDLVVGVVE 119

Query: 275 KI 276
           K+
Sbjct: 120 KM 121


>UniRef50_B9K7V5 Purine nucleoside phosphorylase n=1 Tax=Thermotoga neapolitana DSM
           4359 RepID=B9K7V5_THENN
          Length = 148

 Score =  134 bits (338), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 39/108 (36%), Positives = 57/108 (52%), Gaps = 1/108 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
             + IK      +P +  +LGSG  +  + ++N   I Y+ +P FP  TV GH+G+LV G
Sbjct: 12  ASEYIKER-TSVSPEILIVLGSGFSSFVEAMDNCTTIDYKDIPHFPQPTVEGHSGKLVFG 70

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
            ++  PV+ M GR H YEG     +   I   K LG + +  TNAAG 
Sbjct: 71  IVKDRPVMVMAGRFHLYEGHAPQRVAFPIYVAKFLGVKGVIVTNAAGG 118


>UniRef50_B5JG81 Phosphorylases family 2 n=1 Tax=Verrucomicrobiae bacterium DG1235
           RepID=B5JG81_9BACT
          Length = 230

 Score =  133 bits (334), Expect = 8e-30,   Method: Composition-based stats.
 Identities = 47/200 (23%), Positives = 83/200 (41%), Gaps = 13/200 (6%)

Query: 80  VCMKGRGHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           V +   G         +   A I     LG   +   ++ GS  P++  GSLV+  D+++
Sbjct: 39  VVLNRHGFERPLPPHAVNYRANIEALCQLGIRSVVTLSSVGSADPDLPPGSLVSCSDYMS 98

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFE 197
             P T +    DDR       L+N +       L  +A      +  + V++   GP FE
Sbjct: 99  FAPKTFI----DDRTSAFAPVLSNPH-------LAGIASRSSVEIVRDKVYMQTRGPRFE 147

Query: 198 TAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAA 257
           T AE+R ++ +G DVVGM+   E        ++V A   + N A G++  +LS     A 
Sbjct: 148 TKAEVRAIRTLGADVVGMTFGNEADLLLERGIEVTAFCMVDNFAHGVNSAELSMEAFEAL 207

Query: 258 AELSKQNFINLICGFLRKIA 277
              ++      +   +  ++
Sbjct: 208 VASNQVRINQFLSDLVDYLS 227


>UniRef50_A4IXW9 Phosphorylase family 2/alpha-beta hydrolase fold protein n=18
           Tax=Francisella RepID=A4IXW9_FRATW
          Length = 611

 Score =  132 bits (332), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 51/252 (20%), Positives = 87/252 (34%), Gaps = 16/252 (6%)

Query: 29  AFILGSGLGALADQIENAVAISYEKLPGFPVSTVHG-HAGELVLGHLQGVPVVCMKGRGH 87
           A +  SG  +  D         +E +   P  T  G  +  L    ++   V+ +   G 
Sbjct: 3   AIVGSSGFESFDD---------FEIIEELPRETPFGLCSNGLFKIKVEDKEVLFLNRTGL 53

Query: 88  FYEGRGMTIMTDA-IRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG-TPM 145
                   I   A I   K  G   +   ++  SLR E+  G +V     I+        
Sbjct: 54  GQNILPHQINYKANIYALKKYGATSIIALSSVRSLREELKPGDMVIPYQFIDRTKSLREF 113

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIRM 204
                      + SL+          ++   KE  F +  +  +V   GP F T  + + 
Sbjct: 114 TFCEQGLLN--YVSLSKPITESIAEEIRAKKKEFDFEIHFKQSYVCIEGPQFPTIIDAKC 171

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
            Q +GG V+GM+  PE   AR   L  ++ + I +      DV+ +    L   E S   
Sbjct: 172 FQSMGGGVIGMTAFPEFALAREAGLNYISCNFIVDYVPWSYDVR-NLYNVLEIRETSNLK 230

Query: 265 FINLICGFLRKI 276
              L+   +  +
Sbjct: 231 AEKLVKWLVNNL 242


>UniRef50_C1HCE7 Purine nucleoside phosphorylase n=1 Tax=Paracoccidioides
           brasiliensis Pb01 RepID=C1HCE7_PARBA
          Length = 243

 Score =  130 bits (328), Expect = 4e-29,   Method: Composition-based stats.
 Identities = 61/239 (25%), Positives = 92/239 (38%), Gaps = 37/239 (15%)

Query: 6   FSHNPLFCIDIIKTYKP--DFTPRVAFILGSGLGALADQIEN--AVAISYEKLPGFPVST 61
           F      C   ++   P     PR A I GSGLG LA+ +         Y  +P FPVST
Sbjct: 7   FQQAQETC-SYLRERLPVELQKPRFAIICGSGLGGLAESVNKSPKAEFDYASIPHFPVST 65

Query: 62  VHGHAGELVLGHLQGVPVVCMKGRGHFYEG-----RGMTIMTDAIRTFKLL-GC--ELLF 113
            +    +  +  L+           +  +        +          KL+ G   E + 
Sbjct: 66  GNLCVVKERITQLESTWPGSFNNEVYLPDNVSNDDANVNACAVPGHVGKLVFGILGENIA 125

Query: 114 CTNAAGSLRPEVGAGSLVALKDHI---NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRA 170
            T+AAG L PE   G +V L DHI         P+ G ND+ FG RF  L++AYD   R 
Sbjct: 126 VTSAAGGLNPEYEVGDIVILNDHIFLAGLAGIHPLRGANDNEFGVRFPPLSDAYDLGLRK 185

Query: 171 LLQKVAKEEGFPLTEGVF---VSYPGPN-------FETAAEI-----RMMQIIGGDVVG 214
                 +    P  + V+   +   GP        + ++A+I     + ++    D VG
Sbjct: 186 ------ECPSRPGEKRVYEEFMHCWGPRRELNAGYYASSAQISLECQQFLKSSWLDTVG 238


>UniRef50_Q4P1A5 Putative uncharacterized protein n=1 Tax=Ustilago maydis
           RepID=Q4P1A5_USTMA
          Length = 180

 Score =  130 bits (328), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 59/233 (25%), Positives = 85/233 (36%), Gaps = 62/233 (26%)

Query: 1   MSQVQFSHNPLF---CIDIIKTYKPDF--TPRVAFILGSGLGALADQIENAVAISYEKLP 55
           MS V     P+     ++ I+   P    +P+   I GSGL  LA  +E+AV + Y  +P
Sbjct: 1   MSNVDLDSLPVQFKQAVEAIRAAVPAELASPKWGIICGSGLSGLASTLESAVHVPYTSIP 60

Query: 56  GFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCT 115
           GF  STV GH   L  G                Y     +     +              
Sbjct: 61  GFAESTVQGHTSSLAFG----------------YLSTTPSKRVAVVACL----------- 93

Query: 116 NAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKV 175
                                     G       +      F  L+NAYD E R  L + 
Sbjct: 94  --------------------------GRFHT--YEGHSAATFPPLSNAYDLELRLALYRA 125

Query: 176 AKEEGF--PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARH 226
           A++      L  G +    GP++E+ A+   ++ +G D VGMS VPEVI+A H
Sbjct: 126 AEKLSLLDSLASGTYAYVLGPSYESRADANFLKSVGADAVGMSTVPEVIAAAH 178


>UniRef50_UPI0001926077 PREDICTED: similar to nucleoside phosphorylase, partial n=1
           Tax=Hydra magnipapillata RepID=UPI0001926077
          Length = 117

 Score =  129 bits (326), Expect = 8e-29,   Method: Composition-based stats.
 Identities = 46/94 (48%), Positives = 58/94 (61%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           K    P +  I GSGLG L + IEN    SYE +PGFPVSTV GHAG+LV G ++   +V
Sbjct: 23  KTQLRPTIGVICGSGLGGLVNNIENKEEFSYEDIPGFPVSTVKGHAGKLVFGTIKEKILV 82

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFC 114
           C++GR HFYEG G+   T  +R   LLG + L  
Sbjct: 83  CLQGRFHFYEGHGINKCTLPVRVMALLGIKTLMS 116


>UniRef50_UPI0001C31DF7 S-methyl-5''''-thioadenosine phosphorylase n=1 Tax=Conexibacter
           woesei DSM 14684 RepID=UPI0001C31DF7
          Length = 264

 Score =  128 bits (322), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 62/259 (23%), Positives = 97/259 (37%), Gaps = 20/259 (7%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR- 85
           RV  I GSG   L    +         +PG  V T  G A EL  G   GV VV +    
Sbjct: 2   RVGIITGSGSYVLPHVAD--------GVPGRVV-TRFGTA-ELTRGTFAGVDVVYVSRHL 51

Query: 86  -GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDH---INTMP 141
            GH      +    + I      G + +      GSL   +  G+LV   D     N +P
Sbjct: 52  PGHRLLSSQVRHRAN-IVALAEAGVDAIVAVTICGSLDASLPPGALVVFDDLYFPSNRLP 110

Query: 142 GTPMVGLNDDRF--GERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFET 198
              +  L+DD    G   +     +    R  L   A+  G+   +G  +    GP F T
Sbjct: 111 DGSICTLHDDPGASGRGHWIFDLPFSQPLREALLTGARSAGYAARDGGCYAHTDGPRFNT 170

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS-DVKLSHAQTLAA 257
            AE+R +  IG   V  +  PE++ +    +    +  IT+ A G++ D      +    
Sbjct: 171 RAELRALMQIGVKAVSQTAGPEIVLSGEAGVPYALLGFITDYANGINPDDPTPVDELARL 230

Query: 258 AELSKQNFINLICGFLRKI 276
            + S     +++   L +I
Sbjct: 231 LDASGDIVADVLAATLPRI 249


>UniRef50_A7I6C4 Purine phosphorylase, family 2 n=2 Tax=Genera incertae sedis
           RepID=A7I6C4_METB6
          Length = 223

 Score =  128 bits (321), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 54/249 (21%), Positives = 99/249 (39%), Gaps = 28/249 (11%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +  I G+ L              +  LP     TV    GE  L  L G  +V +    +
Sbjct: 2   LGIIGGTSL-------------LFSTLPALKKETVATPFGEAEL--LCG-DIVMLMRHQY 45

Query: 88  FYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG 147
                 +    + +    + G + +    ++GSL+ E+  G+ +   D+++ M   P + 
Sbjct: 46  GRPPHRINYRAN-LAAMAISGVDHIVAFGSSGSLKKEIPPGTTLIPTDYVS-MADIPSIH 103

Query: 148 LNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQI 207
            +         ++ +      RAL +K+A         GV+V   GP  ET  E+  +  
Sbjct: 104 DH---------AIEHVRPELSRALAEKLAAVVPEARLGGVYVQTRGPRIETVTEVAALAQ 154

Query: 208 IGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFIN 267
           I  DVVGM+V  E   A   D++  A+  I N A GL    L+    L+ ++   +    
Sbjct: 155 I-ADVVGMTVASEATLACELDMEFAALCTIDNYANGLGAEVLTFEHILSISKAHSRRTEE 213

Query: 268 LICGFLRKI 276
           ++   +R++
Sbjct: 214 VLGAIIREM 222


>UniRef50_D0NYY4 Putative uncharacterized protein n=1 Tax=Phytophthora infestans
           T30-4 RepID=D0NYY4_PHYIN
          Length = 265

 Score =  121 bits (304), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 57/267 (21%), Positives = 94/267 (35%), Gaps = 32/267 (11%)

Query: 25  TPRVAFILGSGLGAL----ADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPV- 79
           T  +  I GS L       +  +E  V   +          V  H G    G        
Sbjct: 5   THVLGVIGGSSLFHAKSFSSGLVEQVVETEFG--------AVVCHVGTWPSGSQDETSPA 56

Query: 80  ---VCMKGR-----GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
              V ++       G + + R +     A+   K L CE +    + GS+ P+VG G  V
Sbjct: 57  LQLVFVQRHHADPDGKYRQPRKINFRAIAL-ALKSLRCEAVVGIYSVGSMTPKVGVGRFV 115

Query: 132 ALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF-PLTEGVFVS 190
             +D       +P   ++  +  +          A+ +  L +     GF P   GV+V 
Sbjct: 116 VPEDFF-----SPFDIMHVSKDYDAHV--VPELHAKLKTALVQALTGGGFDPHDGGVYVQ 168

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
             GP FET +E+R     G  ++GM+   E        +     S + NMA G+ D  L+
Sbjct: 169 TAGPRFETKSEVRFFAQFG-QLIGMTGANEAELLNELRVPFAMFSIVDNMANGMGD-PLT 226

Query: 251 HAQTLAAAELSKQNFINLICGFLRKIA 277
                A  + +           L ++A
Sbjct: 227 LEAFKATQKANADLMERAFVHTLNELA 253


>UniRef50_Q9RKG9 Putative phosphorylase n=1 Tax=Streptomyces coelicolor
           RepID=Q9RKG9_STRCO
          Length = 262

 Score =  119 bits (298), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 63/261 (24%), Positives = 95/261 (36%), Gaps = 23/261 (8%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL--GHLQGVPVVCMKG 84
           R+  I GSG                  L G    TV    G + +  G L G  +V +  
Sbjct: 2   RIGVITGSGSYDWP------------HLEGAAERTVVTEHGAVTVTEGRLGGAEIVQLSR 49

Query: 85  RG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDH---INT 139
            G  H      +    +      +    ++  T   GSL P+V  GSLV   D     N 
Sbjct: 50  HGTGHHRLSSQVDHKANLAALLAVEAEAVVSFT-VCGSLEPDVRPGSLVVFDDLYFPANR 108

Query: 140 MP-GTPMVGLNDDR-FGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNF 196
           +P GTP    +     G   +     +    R  L   A + G P+ T+GV+    GP F
Sbjct: 109 LPDGTPCTWYDTPGGAGRGHWIFDRPFSEPLRQALITAADQTGVPVATQGVYGHVDGPRF 168

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLA 256
            T  E+  +   G   +  +  PEV+ A   +L +V V  +T+ A G++         L 
Sbjct: 169 NTRPEVAALAAAGVSAISQTAGPEVVLAGEAELPMVLVGFVTDYANGVAPEPEPVQALLD 228

Query: 257 AAELSKQNFINLICGFLRKIA 277
               SK  F  L    L  ++
Sbjct: 229 RMAASKDVFAKLAEHALPSLS 249


>UniRef50_C7DHY9 S-methyl-5-thioadenosine phosphorylase n=1 Tax=Candidatus
           Micrarchaeum acidiphilum ARMAN-2 RepID=C7DHY9_9EURY
          Length = 278

 Score =  115 bits (289), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 50/258 (19%), Positives = 92/258 (35%), Gaps = 22/258 (8%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH-AGELVLGHLQGVPVVCMKGRG 86
           V  I G       + +E A    Y +   F   T +G  +  L+LG + GV +  M+   
Sbjct: 18  VGIIGG------PEILELA---DYREKKEF--DTEYGKPSSPLMLGSIAGVDIAAMRRDA 66

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
                  + +  + + I+ F+ LG + +   ++  ++R +  AG  V     IN   G  
Sbjct: 67  IDGGLSPQNIPYLAN-IKAFESLGVKRIIAISSVATMRSDFVAGDFVFPSHFINMSNGRR 125

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNFETAAEI 202
               +              Y ++      K A   G+     E   +   G    T AE 
Sbjct: 126 DTFFDSG--NVLRIGDPKPYCSDIAYWGAKAADNLGYIKYHKESTVIITNGTRRPTLAES 183

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA---E 259
           R+    G DV+     PE++ A+   +   AVS + +    + ++  S    +      +
Sbjct: 184 RLFAGWGCDVIDYYQYPEIVLAKEKGICYGAVSMVLDYDSIVEELGKSFRAYVDMEGQYK 243

Query: 260 LSKQNFINLICGFLRKIA 277
            +      L+   L  IA
Sbjct: 244 RTISGLKALLSEMLPNIA 261


>UniRef50_A8RJ25 Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC
           BAA-613 RepID=A8RJ25_9CLOT
          Length = 289

 Score =  115 bits (288), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 43/230 (18%), Positives = 81/230 (35%), Gaps = 18/230 (7%)

Query: 31  ILGSG-LGA-LADQIE------NAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM 82
           I GSG  G    + +           + +E   G             +    +   V+ +
Sbjct: 14  IGGSGTWGCEFPEDLNMEGITLLKRDMEFETPFGVTACMKLYEMDASITADHKTRQVLYV 73

Query: 83  KGRGHFYEGRGMTIMT---DAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINT 139
               H ++G      T         +  G + +    + G + P +  G ++  +D I+ 
Sbjct: 74  P--FHGWKGLSPYNDTPSERIFWALREAGVKYILADGSGGGINPLLEPGDIICPQDFIDY 131

Query: 140 MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFET 198
                 +G    +F      +      +   +L + A      +   G++     P FE+
Sbjct: 132 TKRVSYLG----KFTPYSMRMREIICPDLHRILLEKASGVFRRVFRTGIYGVAEAPRFES 187

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK 248
           AAEI+ M     DV G +++PE   AR       A+  I+N AEG++   
Sbjct: 188 AAEIQKMYADHCDVCGQTMMPEAALARAIGACYAALYVISNSAEGINPNW 237


>UniRef50_Q2S0L6 5'-methylthioadenosine phosphorylase II n=1 Tax=Salinibacter ruber
           DSM 13855 RepID=Q2S0L6_SALRD
          Length = 263

 Score =  108 bits (270), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 60/257 (23%), Positives = 100/257 (38%), Gaps = 19/257 (7%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQG-VPVVCMKG 84
           P VA ILGS   A AD   + + +  E     PV T  G      +  L     V+   G
Sbjct: 2   PAVAAILGS---AFADAFPDELDLEPE-----PVETEWGTQTLHRVRGLDRPAYVLFRHG 53

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHI---NTMP 141
             H      +     A    + +GC  L  T++ G L P+V     + + D +   N +P
Sbjct: 54  LPHRLLPNQINYRAQA-AALRAVGCGALLVTSSVGVLDPDVPLYRPLLVDDLLMPDNRLP 112

Query: 142 -GTPMVGLNDDRFGERFFSLAN-AYDAEYRALLQKVAKEEGFPLTEGV-FVSYPGPNFET 198
            G+      +         L +  +     A ++ +A+    P+ + V F    GP  +T
Sbjct: 113 DGSACTMFTEPSEAHGHLVLNDGLFATGLSAQVRTLAEGADAPIADTVAFAYVQGPRSKT 172

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL-AA 257
           AAE RM   +G  V  M++ PEV+ A   ++    +  +      + D      + L A 
Sbjct: 173 AAENRMWPRMGAQVNSMTLGPEVVLANELEIPCAGL--VVGHKYSIPDRDPPEQEALSAT 230

Query: 258 AELSKQNFINLICGFLR 274
            + S+     ++  FLR
Sbjct: 231 LDRSRDEQERVVRAFLR 247


>UniRef50_C5KDS7 Methylthioadenosine/purine nucleoside phosphorylase, putative n=2
           Tax=Perkinsus marinus ATCC 50983 RepID=C5KDS7_9ALVE
          Length = 204

 Score =  107 bits (268), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 38/164 (23%), Positives = 61/164 (37%), Gaps = 22/164 (13%)

Query: 104 FKLLGCELLFCTNAAGSLRPE-VGAGSLVALKDHINT--------MPGTPMVGLNDDRFG 154
              L C+ +    + GS+RP+    G +    D I+           G P VG      G
Sbjct: 5   AHELLCDKIIALASVGSIRPDLFKIGDIAVPTDFIDFAPQRGTMTFWGNPDVGPFSGEKG 64

Query: 155 ERFFSLANAYDAEYRALLQKVA------------KEEGFPLTEGVFVSYPGPNFETAAEI 202
              ++  +  D  +R  +                 E     T+ V+    GP FE+ AE+
Sbjct: 65  RIHYTPCDHDDHVWRKKIAGTLFPFQEGPHIVSLSEANETETDVVYTQTNGPRFESRAEV 124

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD 246
           RM+Q  G  +VGM+   E   A    +    V+ + N+  GL  
Sbjct: 125 RMLQRYG-HLVGMTCASEWTLAGELGVPYAIVAMVDNLGNGLDS 167


>UniRef50_Q67R94 Methylthioadenosine phosphorylase n=1 Tax=Symbiobacterium
           thermophilum RepID=Q67R94_SYMTH
          Length = 251

 Score =  106 bits (265), Expect = 8e-22,   Method: Composition-based stats.
 Identities = 34/121 (28%), Positives = 48/121 (39%), Gaps = 3/121 (2%)

Query: 118 AGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAK 177
              + P +  G LV   D I+     P        +G  F  L   +  E  A L    +
Sbjct: 82  VEPVSPLLEPGDLVVPVDVIDLTRLLPPTFFVGKGYG--FIRLDPPFCPELSAALYAAGR 139

Query: 178 EEGFPLTEG-VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSA 236
           E+      G  +V   G    T AE RM +  G DVVG  +VPE   AR  +L   A++ 
Sbjct: 140 EKTPRAFRGATYVGLDGSREATPAERRMYRAWGADVVGSGLVPEAFLARELELCYAALTV 199

Query: 237 I 237
           +
Sbjct: 200 V 200


>UniRef50_UPI00016A8371 5''''-methylthioadenosine phosphorylase n=2 Tax=pseudomallei group
           RepID=UPI00016A8371
          Length = 271

 Score =  104 bits (260), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 57/267 (21%), Positives = 103/267 (38%), Gaps = 25/267 (9%)

Query: 27  RVAFILGSGLG-ALADQIENAVAIS-YEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           R+A I G+GL   L   + N   I       G    TV         G + G+  + +  
Sbjct: 6   RIAIIAGTGLARGLDAFLGNRETIENVRVTFGRRSGTVL----HYTTGRIGGIEAIVLPR 61

Query: 85  RG---HFYEGRGMTIMT-----DAIRTFKLLGCELLFCTNAAGSLRPEVGAGS---LVAL 133
            G      +     ++        I     LG + ++  N+ G++  ++   +    +A 
Sbjct: 62  HGPTLAIPDRSPAELVAELGHEAHIWHLHELGVQAVYAFNSVGAIDLDLPLAADNVFLAP 121

Query: 134 KDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYP 192
            D+   +        N  +      S+   +DA  RA     A + G  L T+G+++   
Sbjct: 122 DDYARGLSSVSHSFGNLAK--HVHPSMREPFDARLRANFALAAGKVGAKLLTQGLYIQSG 179

Query: 193 GPNFETAAEIRMMQII----GGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS-DV 247
           G  FE+AAE+   + +       V+GM+   E++  R  ++    + A  N AEGL  D 
Sbjct: 180 GDAFESAAEVETYRRVYQGRRNRVLGMTAGAELVLCRQMEIPYALICANCNWAEGLDPDN 239

Query: 248 KLSHAQTLAAAELSKQNFINLICGFLR 274
            ++HA  LA  + +      +    LR
Sbjct: 240 AVTHAFVLAGMQPAAATLAKIAEAVLR 266


>UniRef50_C8SNV7 Purine or other phosphorylase family 1 n=2 Tax=Mesorhizobium
           RepID=C8SNV7_9RHIZ
          Length = 312

 Score = 97.2 bits (241), Expect = 5e-19,   Method: Composition-based stats.
 Identities = 43/234 (18%), Positives = 76/234 (32%), Gaps = 34/234 (14%)

Query: 28  VAFILGS---GLGALADQIENAVAISYEKLPGFPVSTVHGHA----------GELVLGHL 74
           +A I GS   GL A  + ++     +  +   F   T  G +             V G +
Sbjct: 29  LAIITGSANWGL-AFPEDVKFESVRTLRRDMSF--ETPFGRSDNWKLLEFDASITVEGKM 85

Query: 75  QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALK 134
                +CM   G+  +    +    A       G   +   +  G++   +  G +V   
Sbjct: 86  --KRALCMYSHGNPRDHIDHSCHRRAFWVLMEAGVRQVLSCSTIGAVNKAIKPGDMVVNA 143

Query: 135 DHINTMPGTPMVGLNDDRFGERFFSLA--NAYDAEYRALLQKVAKEE--------GFPLT 184
           D I        +       G + F  +          A+L + A+          G    
Sbjct: 144 DIIELTQTPFSLLP-----GRQSFDCSGKQIVCPRCAAVLVETARRHWPAECRVHGIE-Q 197

Query: 185 EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
           + V     GP   T AE    + +G DV+  S+ PE   +R      V ++ +T
Sbjct: 198 QLVAGHCYGPRLTTPAEALAFRNLGADVLNHSIAPEATLSREIGACFVPLAFVT 251


>UniRef50_UPI000038263C COG0005: Purine nucleoside phosphorylase n=1 Tax=Magnetospirillum
           magnetotacticum MS-1 RepID=UPI000038263C
          Length = 162

 Score = 95.7 bits (237), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 38/132 (28%), Positives = 55/132 (41%), Gaps = 6/132 (4%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQI-ENAVAISYEKLPGFPVSTVHGHAGELV 70
              D I          +A +LGSG G  A+ + E    +   ++PGF    V GH     
Sbjct: 24  AAADHIAQATGVEGHDMALVLGSGWGGAAELLGEVVAEVPTHEIPGFSAPAVAGHLSVTR 83

Query: 71  LGHLQG-----VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
              ++         + +  R H YEG+G+  +   +RT    G E L  TN  G L  E 
Sbjct: 84  SIRVERADGSVRHALVLGSRTHLYEGKGVRAVVHGVRTAAATGAETLILTNGCGGLNQEW 143

Query: 126 GAGSLVALKDHI 137
           GAG+ V L  H+
Sbjct: 144 GAGTPVLLSXHM 155


>UniRef50_A9WPZ3 5'-methylthioadenosine phosphorylase n=1 Tax=Renibacterium
           salmoninarum ATCC 33209 RepID=A9WPZ3_RENSM
          Length = 160

 Score = 86.8 bits (214), Expect = 7e-16,   Method: Composition-based stats.
 Identities = 23/112 (20%), Positives = 40/112 (35%), Gaps = 2/112 (1%)

Query: 156 RFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRMMQIIGGDVVG 214
           +    A+AY    R L+    +E   P    GV     GP F + AE   +   G +++ 
Sbjct: 2   QHIPAADAYCQTLRGLMVDSLRELAEPHQSTGVVAVINGPRFSSPAESAWLASAGCELIS 61

Query: 215 MSVVPEVISARHCDLKVVAVSAITNMAEG-LSDVKLSHAQTLAAAELSKQNF 265
           M+   E I A   +L    +  IT+   G      ++          ++   
Sbjct: 62  MTQYTEPILAAELNLGFATLCYITDADTGHDGSEPVTAQLVFERLRAAQPRI 113


>UniRef50_P23139 Uncharacterized 25.8 kDa protein in petC 3'region n=1
           Tax=Rhodospirillum rubrum RepID=YPE2_RHORU
          Length = 238

 Score = 85.7 bits (211), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 27/139 (19%), Positives = 48/139 (34%), Gaps = 11/139 (7%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM-- 82
            P +  I GSG+  + D +E A   + E   G         + +++ G L G+ +  +  
Sbjct: 7   QPVLGVIGGSGVYDI-DGLEGARWQTVESPFGDV-------SDQILRGTLDGLEMAFLPR 58

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            GRGH      +    + I   K  G   +   +A GSL  ++  G+ V     I+    
Sbjct: 59  HGRGHVLAPSDVNYRAN-IDALKRAGVTEILSVSAVGSLAEDLPPGTFVIADQFIDRTFA 117

Query: 143 TPMVGLNDDRFGERFFSLA 161
                             +
Sbjct: 118 REKSFFRQGSGRPCQHGPS 136


>UniRef50_C0W509 Possible purine-nucleoside phosphorylase n=1 Tax=Actinomyces
           urogenitalis DSM 15434 RepID=C0W509_9ACTO
          Length = 283

 Score = 82.6 bits (203), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 43/185 (23%), Positives = 65/185 (35%), Gaps = 14/185 (7%)

Query: 54  LPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLF 113
           LPG     V G    L      G+ V+  +GR   YEG+    +T   R     G     
Sbjct: 65  LPGVSAPQVPGQEDLLTSHDRGGLGVLVARGRTCLYEGKPARRVTGLARLAAGAGVRAAL 124

Query: 114 CTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQ 173
             + A SL      G  +A+ DH+N               G   F      DA +   L 
Sbjct: 125 MVSRASSLGQA-SLGDFLAVADHLNLT-------------GSPLFPATQCVDASWDEDLT 170

Query: 174 KVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVA 233
                       GV    PGP   + +E+ +M  +G D V M  V E ++     ++V  
Sbjct: 171 NAVSRIDGVRGAGVAALVPGPVRPSRSEVTLMSGLGADAVVMDGVAEAMALAARGVRVAG 230

Query: 234 VSAIT 238
           ++ + 
Sbjct: 231 LAYVD 235


>UniRef50_UPI000187D203 hypothetical protein MPER_09068 n=1 Tax=Moniliophthora perniciosa
          FA553 RepID=UPI000187D203
          Length = 73

 Score = 74.5 bits (182), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 30/71 (42%), Positives = 35/71 (49%), Gaps = 3/71 (4%)

Query: 4  VQFSHNPL-FCIDIIKTYKPD--FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
          VQ S +P    ID I    P     PRV  I GSGL  LA  ++  V + Y+ LPGF  S
Sbjct: 3  VQGSASPFDATIDTIHRIVPQNLQKPRVGIICGSGLSGLAASLKETVPLPYDTLPGFAQS 62

Query: 61 TVHGHAGELVL 71
          TV GH   L  
Sbjct: 63 TVPGHKSSLAF 73


>UniRef50_Q9NRK7 MTAP (Fragment) n=2 Tax=Homo sapiens RepID=Q9NRK7_HUMAN
          Length = 112

 Score = 73.4 bits (179), Expect = 9e-12,   Method: Composition-based stats.
 Identities = 14/55 (25%), Positives = 26/55 (47%), Gaps = 5/55 (9%)

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL 255
           E  M +  G DV+ M+ VPEV+ A+   +   +++  T+      D    H + +
Sbjct: 1   ESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDY-----DCWKEHEEAM 50


>UniRef50_A9WPZ4 5'-methylthioadenosine phosphorylase n=1 Tax=Renibacterium
           salmoninarum ATCC 33209 RepID=A9WPZ4_RENSM
          Length = 121

 Score = 68.7 bits (167), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 23/107 (21%), Positives = 36/107 (33%), Gaps = 11/107 (10%)

Query: 17  IKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQG 76
           I + +    P V  I GSG+  L         I  +   G   + V        +  L G
Sbjct: 14  ISSDETQPRPVVGIIGGSGMYQLPGS-RTVQTIRLDTPFGQTSAPVT-------IAELDG 65

Query: 77  VPVVCMKGR--GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSL 121
             V  +     GH    + +    + I     LG + +  + A GSL
Sbjct: 66  QTVAFLPRHGGGHKVPPQQINYRAN-IWALASLGVKAIISSAAVGSL 111


>UniRef50_A4GI77 Possible methylthioadenosine phosphorylase n=1 Tax=uncultured
           marine bacterium HF10_29C11 RepID=A4GI77_9BACT
          Length = 162

 Score = 65.3 bits (158), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 26/156 (16%), Positives = 51/156 (32%), Gaps = 7/156 (4%)

Query: 27  RVAFILGSGLGALADQIENA-VAISYEKLPGFPVSTVHGHAGELVLGHLQG---VPVVCM 82
           R+A I G+GL  +A     A   +       F V T +G+          G     +V +
Sbjct: 3   RLAIIGGTGLLNMATAQPFADADLEVLATDSFEVETPYGNVPLKSFQLQHGSSEKTLVFL 62

Query: 83  KGRGHFYEGRGMTIMTD---AIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINT 139
           +   +  +        +    I   K    + +    + G L  +   G +     +I+ 
Sbjct: 63  QRHHNEGKPNKPPHNINHHANIWALKNANVDAILSVCSVGCLVQDFPPGRVGLADQYIDF 122

Query: 140 MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKV 175
              T     ++  F         A +A    +L++V
Sbjct: 123 TGQTTTFYDDEAEFTSVTVPFDRAMNASLELVLRQV 158


>UniRef50_A9B0R0 Methylthioadenosine phosphorylase n=1 Tax=Herpetosiphon aurantiacus
           ATCC 23779 RepID=A9B0R0_HERA2
          Length = 220

 Score = 61.0 bits (147), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 20/149 (13%), Positives = 40/149 (26%), Gaps = 12/149 (8%)

Query: 90  EGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLN 149
           E         AI   K  G   +    +       +    ++     ++           
Sbjct: 33  EPNPHA----AIYAAKSQGVTWIIEAVSMLPCDGLLQPDDILIPDQLVDLTQQRSSTFFR 88

Query: 150 DDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAEIRMMQII 208
           +  +G  F    + +  + RA L   A+     + + G          +T  E    Q  
Sbjct: 89  NRGYG--FIGQNSVWCPDLRASLLTAAQSISQRVFSRGTLAVGEA---DTTLE--AAQTW 141

Query: 209 GGDVVGMSVVPEVISARHCDLKVVAVSAI 237
               +  S  P    A+  +L    V  +
Sbjct: 142 QAHGLSRSAAPAAYLAKELELCYAVVGIV 170


>UniRef50_C0QJ87 Putative purine nucleoside phosphorylase n=1 Tax=Desulfobacterium
           autotrophicum HRM2 RepID=C0QJ87_DESAH
          Length = 258

 Score = 57.9 bits (139), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 40/217 (18%), Positives = 65/217 (29%), Gaps = 21/217 (9%)

Query: 38  ALADQIENAVAISYEKLPGFP-------VSTVHGHAGELVLGHLQGVPVVCMKG------ 84
             +D  + A+   Y   PGF        VST                  + M        
Sbjct: 5   TWSDLNDRAIIQPYGARPGFESGAVAVMVSTAPDFNYLKANARGNTCSPLFMGSVFTETE 64

Query: 85  RGHFYEGRGM--TIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
           +G  + G  M     T         G   L      GSL  ++  G +V +   I     
Sbjct: 65  KGASFTGPHMGAPYATMVEEALIAKGARTLLVFGWCGSLSTDLAIGDIVLVDGAI----A 120

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEI 202
                 N    GE F  +    D++ RA L       G     G   +  G   ET  ++
Sbjct: 121 DEGTSRNYMEPGEDFPRILP--DSDLRARLGNELSAGGIAFKSGTLWTTDGIYRETPKKV 178

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
              +  G   V M         R+  +++ A+  +++
Sbjct: 179 EFFRNRGAAGVDMECSALFAVGRYRKVRMAAILVVSD 215


>UniRef50_A0LI68 Purine and other phosphorylases, family 1 n=1 Tax=Syntrophobacter
           fumaroxidans MPOB RepID=A0LI68_SYNFM
          Length = 264

 Score = 56.8 bits (136), Expect = 9e-07,   Method: Composition-based stats.
 Identities = 34/185 (18%), Positives = 57/185 (30%), Gaps = 14/185 (7%)

Query: 55  PGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFC 114
           P  P      +  +   G   GVP+  +          G       +     LG   +F 
Sbjct: 56  PQRPSMNNRIYLSDAYAGEYGGVPIALVG------PMLGAPQAVMVLEKMIALGVRKVFA 109

Query: 115 TNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQK 174
               GSL+  V  G +V      +T         +    G+     +N    E R  L  
Sbjct: 110 VGWCGSLQGRVSVGDVVVP----DTAVSEEGTSDHYPLGGDALRGPSN----ELRDSLIA 161

Query: 175 VAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAV 234
                G  + EG   +   P  ET  ++   Q  G   V M     +  A    +++  V
Sbjct: 162 DLSARGVKVHEGSVWTTDAPYRETRRKVLQYQNSGVLAVDMETSALLTVAAFRQIRLAVV 221

Query: 235 SAITN 239
             +++
Sbjct: 222 LTVSD 226


>UniRef50_C8QZD7 Purine or other phosphorylase family 1 n=1 Tax=Desulfurivibrio
           alkaliphilus AHT2 RepID=C8QZD7_9DELT
          Length = 247

 Score = 52.9 bits (126), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 37/190 (19%), Positives = 60/190 (31%), Gaps = 28/190 (14%)

Query: 51  YEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCE 110
           Y   PG   +T  G  G  + G   G PV  M                 A+     LG  
Sbjct: 52  YSFFPGALHATPTG--GAWLAGPAVGAPVAVM-----------------ALEKLVALGAT 92

Query: 111 LLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRA 170
            +      G+L P V  G +V              +          F   + A D     
Sbjct: 93  AVISVGWCGALAPGVEVGDIVLPD---------TALSEEGTSAHYPFAGQSVAADPALNL 143

Query: 171 LLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLK 230
            LQ++    GF +  G   +   P  ET A++   +  G   V M        A +  + 
Sbjct: 144 KLQRLLVGAGFTVHGGPVWTTDAPYRETWAKVARYRRRGILAVEMEFAALAAVAAYRGVP 203

Query: 231 VVAVSAITNM 240
           + +V  ++++
Sbjct: 204 LASVLLVSDL 213


>UniRef50_A6RV57 Putative uncharacterized protein n=1 Tax=Botryotinia fuckeliana
           B05.10 RepID=A6RV57_BOTFB
          Length = 111

 Score = 52.2 bits (124), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 12/63 (19%), Positives = 23/63 (36%)

Query: 215 MSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLR 274
           MS +PE   AR  ++    +   T+     S   +     +     + QN   L+   L 
Sbjct: 1   MSALPEAKLAREAEMVYQMICMATDYDCWHSTADVDVEMVMGHMHANGQNAKRLVGAVLD 60

Query: 275 KIA 277
            ++
Sbjct: 61  ALS 63


>UniRef50_D1AJ63 Purine or other phosphorylase family 1 n=3 Tax=Bacteria
           RepID=D1AJ63_SEBTE
          Length = 249

 Score = 51.4 bits (122), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 41/214 (19%), Positives = 80/214 (37%), Gaps = 19/214 (8%)

Query: 68  ELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGA 127
           E   G LQG  VV +K           T +   IR FK    + +  T  AG++  ++  
Sbjct: 50  EFYSGTLQGKDVVLLKSGVGKVNSAMATDI--LIREFK---ADKIIFTGVAGAVNNKLNV 104

Query: 128 GSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAY-DAEYRALLQKVAKEE--GFPLT 184
           G +V   D +     T      +             Y D    +L +  A++      + 
Sbjct: 105 GDVVISVDLVEHDFDT--TAFGEKPGNVPGSDNGKFYADQSLISLAETSAQKVLGKTHVF 162

Query: 185 EGVFVSYPGPNF-ETAAEIRMM-QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAE 242
           +G      G  F    A+++++ +  G   V M        A    +  V + AI++ A+
Sbjct: 163 KGTIA--TGDQFIADKAKVKVLEETFGAWAVEMEGASVAHVAALYKVPFVVIRAISDKAD 220

Query: 243 GLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           G     +++ +    +  + +N I ++   L+K+
Sbjct: 221 G--SAHVTYDEF---SNKAAENSIKIVNEMLKKM 249


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_P77834 Purine nucleoside phosphorylase 1 n=41 Tax=Bacil...   349   4e-95
UniRef50_Q2B6A0 Purine nucleoside phosphorylase n=12 Tax=Bacilli...   346   6e-94
UniRef50_Q65HU0 PunA n=9 Tax=Firmicutes RepID=Q65HU0_BACLD            345   8e-94
UniRef50_P46354 Purine nucleoside phosphorylase 1 n=69 Tax=Bacte...   344   2e-93
UniRef50_A7GSB0 Purine nucleoside phosphorylase I, inosine and g...   342   9e-93
UniRef50_C1F7J2 Purine nucleoside phosphorylase I, inosine and g...   334   2e-90
UniRef50_B1YM96 Purine nucleoside phosphorylase I, inosine and g...   333   3e-90
UniRef50_A3DEQ4 Purine nucleoside phosphorylase I, inosine and g...   331   2e-89
UniRef50_P45563 Xanthosine phosphorylase n=57 Tax=cellular organ...   328   2e-88
UniRef50_A9KIZ4 Inosine guanosine and xanthosine phosphorylase f...   326   7e-88
UniRef50_B5R3U9 Xanthosine phosphorylase n=53 Tax=Enterobacteria...   324   2e-87
UniRef50_Q23U21 Purine nucleoside phosphorylase n=1 Tax=Tetrahym...   321   1e-86
UniRef50_A6BDL0 Putative uncharacterized protein n=1 Tax=Dorea l...   321   2e-86
UniRef50_B9MKK7 Inosine guanosine and xanthosine phosphorylase f...   321   2e-86
UniRef50_A5IBS6 Xanthosine phosphorylase n=5 Tax=Legionella RepI...   316   4e-85
UniRef50_P00491 Purine nucleoside phosphorylase n=19 Tax=Coeloma...   316   4e-85
UniRef50_C9LGF9 Purine nucleoside phosphorylase I, inosine and g...   316   6e-85
UniRef50_B8HVY6 Inosine guanosine and xanthosine phosphorylase f...   316   7e-85
UniRef50_A6NWZ5 Putative uncharacterized protein n=1 Tax=Bactero...   315   8e-85
UniRef50_P23492 Purine nucleoside phosphorylase n=47 Tax=Metazoa...   314   1e-84
UniRef50_C7M8V2 Inosine guanosine and xanthosine phosphorylase f...   314   2e-84
UniRef50_Q3B5L6 Purine nucleoside phosphorylase I, inosine and g...   314   3e-84
UniRef50_A9KIE8 Inosine guanosine and xanthosine phosphorylase f...   312   7e-84
UniRef50_Q1IM44 Purine nucleoside phosphorylase I, inosine and g...   312   8e-84
UniRef50_D0LL71 Purine nucleoside phosphorylase I, inosine and g...   312   1e-83
UniRef50_B6J4B4 Xanthosine phosphorylase n=8 Tax=Gammaproteobact...   311   2e-83
UniRef50_D0NTD2 Purine nucleoside phosphorylase 1 n=5 Tax=cellul...   309   5e-83
UniRef50_A6GZM2 Purine-nucleoside phosphorylase n=3 Tax=Bacteroi...   309   5e-83
UniRef50_Q0TU47 Purine nucleoside phosphorylase n=7 Tax=Clostrid...   309   6e-83
UniRef50_Q95TC1 GH03781p n=13 Tax=cellular organisms RepID=Q95TC...   309   6e-83
UniRef50_Q6MGR6 Pnp protein n=1 Tax=Bdellovibrio bacteriovorus R...   308   1e-82
UniRef50_UPI0000522022 PREDICTED: similar to nucleoside phosphor...   308   2e-82
UniRef50_C1TMH4 Purine nucleoside phosphorylase I, inosine and g...   307   4e-82
UniRef50_C3J8Q8 Purine nucleoside phosphorylase I, inosine and g...   305   1e-81
UniRef50_Q7KV94 CG16758, isoform B n=33 Tax=cellular organisms R...   305   1e-81
UniRef50_C7LVA5 Inosine guanosine and xanthosine phosphorylase f...   304   2e-81
UniRef50_A7HJP7 Purine nucleoside phosphorylase I, inosine and g...   303   3e-81
UniRef50_B6YR86 Purine-nucleoside phosphorylase n=1 Tax=Candidat...   303   5e-81
UniRef50_A7S700 Predicted protein n=3 Tax=cellular organisms Rep...   303   5e-81
UniRef50_A4CJ72 Purine nucleoside phosphorylase n=15 Tax=Bactero...   302   6e-81
UniRef50_D1B5G3 Inosine guanosine and xanthosine phosphorylase f...   302   7e-81
UniRef50_C4QLI3 Purine nucleoside phosphorylase n=2 Tax=Schistos...   302   1e-80
UniRef50_Q5YBA4 Purine nucleoside phosphorylase n=2 Tax=Singapor...   301   2e-80
UniRef50_B0VG85 Purine nucleoside phosphorylase 1 (Purine nucleo...   299   5e-80
UniRef50_A7VBG8 Putative uncharacterized protein n=2 Tax=Clostri...   299   5e-80
UniRef50_A8PXS8 Purine nucleoside phosphorylase I, inosine and g...   299   7e-80
UniRef50_Q9BMI9 Purine-nucleoside phosphorylase n=1 Tax=Schistos...   299   8e-80
UniRef50_D1Y3S3 Purine nucleoside phosphorylase I, inosine and g...   296   8e-79
UniRef50_D2QX64 Purine nucleoside phosphorylase I, inosine and g...   295   1e-78
UniRef50_C8V0B3 Purine nucleoside phosphorylase I, inosine and g...   295   1e-78
UniRef50_D0MFN5 Inosine guanosine and xanthosine phosphorylase f...   295   1e-78
UniRef50_D2MQ16 Purine nucleoside phosphorylase I, inosine and g...   294   2e-78
UniRef50_B7A7P1 Inosine guanosine and xanthosine phosphorylase f...   294   2e-78
UniRef50_C3ZRV1 Putative uncharacterized protein (Fragment) n=1 ...   294   3e-78
UniRef50_C5EQ75 Purine nucleoside phosphorylase I n=1 Tax=Clostr...   293   3e-78
UniRef50_A5USV0 Inosine guanosine and xanthosine phosphorylase f...   292   7e-78
UniRef50_A0NS72 Purine nucleoside phosphorylase n=7 Tax=Alphapro...   292   9e-78
UniRef50_B9WDS7 Purine nucleoside phosphorylase, putative n=14 T...   292   1e-77
UniRef50_Q311R2 Inosine guanosine and xanthosine phosphorylase n...   291   2e-77
UniRef50_A3ZZ29 Purine nucleoside phosphorylase n=1 Tax=Blastopi...   290   4e-77
UniRef50_C3FBK6 Purine nucleoside phosphorylase I, inosine and g...   288   1e-76
UniRef50_B9XJR6 Inosine guanosine and xanthosine phosphorylase f...   288   2e-76
UniRef50_C7MNU9 Inosine guanosine and xanthosine phosphorylase f...   287   2e-76
UniRef50_C1AAZ0 Purine nucleoside phosphorylase n=1 Tax=Gemmatim...   287   4e-76
UniRef50_Q1NL01 Inosine guanosine and xanthosine phosphorylase:P...   286   8e-76
UniRef50_C0BWU4 Putative uncharacterized protein n=1 Tax=Clostri...   285   1e-75
UniRef50_C1C0Q7 Purine nucleoside phosphorylase n=2 Tax=Caligus ...   285   1e-75
UniRef50_B2KC58 Inosine guanosine and xanthosine phosphorylase f...   284   2e-75
UniRef50_A9URE9 Predicted protein n=1 Tax=Monosiga brevicollis R...   282   7e-75
UniRef50_C5NWB5 Purine nucleoside phosphorylase 1 n=1 Tax=Gemell...   281   1e-74
UniRef50_B4D4P3 Inosine guanosine and xanthosine phosphorylase f...   279   6e-74
UniRef50_Q05788 Purine nucleoside phosphorylase n=10 Tax=Sacchar...   278   2e-73
UniRef50_O57865 Uncharacterized protein PH0125 n=36 Tax=Archaea ...   277   2e-73
UniRef50_A9BH77 Purine nucleoside phosphorylase I, inosine and g...   275   1e-72
UniRef50_B6K0G6 Purine nucleoside phosphorylase n=1 Tax=Schizosa...   275   1e-72
UniRef50_B3QTH8 Inosine guanosine and xanthosine phosphorylase f...   275   2e-72
UniRef50_B1GZW7 Purine nucleoside phosphorylase n=1 Tax=uncultur...   273   4e-72
UniRef50_Q9UTG1 Putative purine nucleoside phosphorylase n=4 Tax...   272   7e-72
UniRef50_A9G8Q6 DeoD protein n=8 Tax=Bacteria RepID=A9G8Q6_SORC5      270   2e-71
UniRef50_Q472Z5 Purine nucleotide phosphorylase:Inosine guanosin...   269   8e-71
UniRef50_Q11C51 Inosine guanosine and xanthosine phosphorylase f...   269   8e-71
UniRef50_B8J4B5 Inosine guanosine and xanthosine phosphorylase f...   268   1e-70
UniRef50_Q11M20 Inosine guanosine and xanthosine phosphorylase f...   266   6e-70
UniRef50_C7NVB1 Inosine guanosine and xanthosine phosphorylase f...   265   1e-69
UniRef50_B4MDV7 GJ18292 n=4 Tax=Drosophila RepID=B4MDV7_DROVI         261   2e-68
UniRef50_Q13126 S-methyl-5'-thioadenosine phosphorylase n=55 Tax...   260   3e-68
UniRef50_Q2S0P3 Purine nucleoside phosphorylase n=1 Tax=Saliniba...   259   1e-67
UniRef50_B9ZYX1 Nucleoside phosphorylase n=1 Tax=Dicyema japonic...   258   1e-67
UniRef50_C5P2F4 Purine nucleoside phosphorylase, putative n=2 Ta...   256   6e-67
UniRef50_Q7ZV22 Methylthioadenosine phosphorylase n=20 Tax=Metaz...   255   9e-67
UniRef50_D2L8K6 Inosine guanosine and xanthosine phosphorylase f...   255   9e-67
UniRef50_Q3A2Z8 Xanthosine phosphorylase n=1 Tax=Pelobacter carb...   254   3e-66
UniRef50_B7GAT6 Predicted protein (Fragment) n=2 Tax=Bacillariop...   254   3e-66
UniRef50_D2QX63 Inosine guanosine and xanthosine phosphorylase f...   254   3e-66
UniRef50_A3DD28 Methylthioadenosine phosphorylase n=7 Tax=Clostr...   254   3e-66
UniRef50_B0D4C6 Predicted protein n=3 Tax=Agaricales RepID=B0D4C...   253   4e-66
UniRef50_A9A3N5 Methylthioadenosine phosphorylase n=4 Tax=Archae...   252   1e-65
UniRef50_B3T2V4 Putative phosphorylase family 2 n=2 Tax=environm...   251   2e-65
UniRef50_B8ICG2 Purine nucleotide phosphorylase n=28 Tax=Alphapr...   250   4e-65
UniRef50_Q0W2D2 Putative purine phosphorylase (Family 2) n=1 Tax...   244   3e-63
UniRef50_UPI000038E4F5 5''''-methylthioadenosine phosphorylase I...   244   3e-63
UniRef50_Q3ZZT2 Methylthioadenosine phosphorylase n=7 Tax=cellul...   241   2e-62
UniRef50_Q2CJ93 Purine nucleoside phosphorylase n=1 Tax=Oceanico...   240   3e-62
UniRef50_Q0BRD3 5'-methylthioadenosine phosphorylase n=113 Tax=c...   239   8e-62
UniRef50_O27633 Methylthioadenosine phosphorylase n=7 Tax=Archae...   239   1e-61
UniRef50_P46862 Purine nucleoside phosphorylase n=79 Tax=Actinom...   239   1e-61
UniRef50_C0QPX3 Methylthioadenosine phosphorylase n=6 Tax=Aquifi...   238   2e-61
UniRef50_A4U101 Purine phosphorylase, family 2 n=4 Tax=Proteobac...   238   2e-61
UniRef50_B1I2E1 Methylthioadenosine phosphorylase n=33 Tax=cellu...   238   2e-61
UniRef50_B9KZC3 Methylthioadenosine phosphorylase n=2 Tax=Bacter...   237   2e-61
UniRef50_A3EWJ6 Methylthioadenosine phosphorylase n=2 Tax=Leptos...   236   5e-61
UniRef50_Q83H43 Purine nucleoside phosphorylase n=3 Tax=Trophery...   236   6e-61
UniRef50_A2FHY6 Inosine guanosine and xanthosine phosphorylase f...   235   1e-60
UniRef50_D2RKT9 Purine or other phosphorylase family 1 n=1 Tax=A...   234   3e-60
UniRef50_B0K2V3 Purine phosphorylase, family 2 n=10 Tax=Thermoan...   234   3e-60
UniRef50_D1BYW2 Purine nucleotide phosphorylase n=6 Tax=Actinomy...   234   3e-60
UniRef50_A9BDU8 5'-methylthioadenosine phosphorylase n=13 Tax=Cy...   233   4e-60
UniRef50_Q1K0Y4 Inosine guanosine and xanthosine phosphorylase n...   232   8e-60
UniRef50_P81989 Purine nucleoside phosphorylase n=7 Tax=Actinoba...   231   3e-59
UniRef50_C6HVW5 Methylthioadenosine phosphorylase n=1 Tax=Leptos...   230   3e-59
UniRef50_Q1NY44 Methylthioadenosine phosphorylase n=2 Tax=delta ...   230   3e-59
UniRef50_C0W9U9 Purine nucleoside phosphorylase n=1 Tax=Acidamin...   230   5e-59
UniRef50_D1YZM1 5'-methylthioadenosine phosphorylase n=1 Tax=Met...   229   6e-59
UniRef50_P74469 Sll0135 protein n=67 Tax=cellular organisms RepI...   229   9e-59
UniRef50_C4FCF5 Putative uncharacterized protein n=2 Tax=Collins...   229   1e-58
UniRef50_D1A6L7 Methylthioadenosine phosphorylase n=16 Tax=Actin...   229   1e-58
UniRef50_Q0F2U5 Purine nucleoside phosphorylase n=1 Tax=Mariprof...   228   2e-58
UniRef50_Q16MW6 Methylthioadenosine phosphorylase n=6 Tax=Neopte...   228   2e-58
UniRef50_Q60367 Uncharacterized protein MJ0060 n=11 Tax=Methanoc...   227   3e-58
UniRef50_D1C2Y0 Methylthioadenosine phosphorylase n=2 Tax=Bacter...   227   4e-58
UniRef50_B5Y8G4 Methylthioadenosine phosphorylase n=1 Tax=Coprot...   226   5e-58
UniRef50_Q18KQ3 5'-methylthioadenosine phosphorylase MtaP n=4 Ta...   226   5e-58
UniRef50_C7MEB8 Purine nucleotide phosphorylase n=2 Tax=Micrococ...   226   6e-58
UniRef50_B1GZW8 S-methyl-5'-thioadenosine phosphorylase n=1 Tax=...   226   8e-58
UniRef50_Q28ZG3 GA14805 n=2 Tax=pseudoobscura subgroup RepID=Q28...   225   9e-58
UniRef50_C5C9E7 Purine nucleotide phosphorylase n=3 Tax=Actinomy...   225   1e-57
UniRef50_C4Q4X0 Methylthioadenosine phosphorylase, putative n=1 ...   224   2e-57
UniRef50_B4U6Q8 Purine phosphorylase family 2 n=2 Tax=Aquificace...   223   4e-57
UniRef50_Q465I0 Methylthioadenosine phosphorylase n=4 Tax=Methan...   222   8e-57
UniRef50_Q09438 Putative S-methyl-5'-thioadenosine phosphorylase...   222   8e-57
UniRef50_Q47F96 Methylthioadenosine phosphorylase n=7 Tax=Betapr...   221   2e-56
UniRef50_B9CNR2 Purine nucleoside phosphorylase 1 n=2 Tax=Atopob...   221   2e-56
UniRef50_A8B9X8 Purine nucleoside phosphorylase lateral transfer...   221   3e-56
UniRef50_A9GWF6 5'-methyl-5-thioadenosine phosphorylase n=1 Tax=...   220   4e-56
UniRef50_Q7URV0 Purine nucleoside phosphorylase I n=1 Tax=Rhodop...   220   4e-56
UniRef50_C8R2U4 Methylthioadenosine phosphorylase n=1 Tax=Desulf...   220   5e-56
UniRef50_B4CZS2 Methylthioadenosine phosphorylase n=1 Tax=Chthon...   220   6e-56
UniRef50_D2VAE0 Purine phosphorylase family protein n=1 Tax=Naeg...   218   1e-55
UniRef50_C7LA98 FI12502p (Fragment) n=14 Tax=Drosophila RepID=C7...   218   1e-55
UniRef50_B5EMB0 Methylthioadenosine phosphorylase n=15 Tax=Prote...   217   3e-55
UniRef50_C5EEL8 Purine nucleoside phosphorylase n=1 Tax=Clostrid...   217   3e-55
UniRef50_Q5Z1K2 Putative methylthioadenosine phosphorylase n=4 T...   216   5e-55
UniRef50_Q87ZC3 Probable S-methyl-5'-thioadenosine phosphorylase...   215   1e-54
UniRef50_C6DE56 Methylthioadenosine phosphorylase n=1 Tax=Pectob...   213   5e-54
UniRef50_Q21JS6 Methylthioadenosine phosphorylase n=1 Tax=Saccha...   213   5e-54
UniRef50_D2V2R7 5'-methylthioadenosine phosphorylase n=1 Tax=Nae...   212   8e-54
UniRef50_Q1H1A2 Methylthioadenosine phosphorylase n=3 Tax=Bacter...   212   1e-53
UniRef50_B0DVC8 Predicted protein n=3 Tax=Basidiomycota RepID=B0...   211   2e-53
UniRef50_Q87BR7 Probable S-methyl-5'-thioadenosine phosphorylase...   211   2e-53
UniRef50_B9KXK8 Purine nucleoside phosphorylase n=2 Tax=Thermomi...   210   3e-53
UniRef50_A3TNF6 Methylthioadenosine phosphorylase n=1 Tax=Janiba...   210   5e-53
UniRef50_Q9W1K6 CG18128 n=7 Tax=melanogaster group RepID=Q9W1K6_...   209   7e-53
UniRef50_C5TP90 Methylthioadenosine phosphorylase n=5 Tax=Neisse...   208   1e-52
UniRef50_B7RUB3 Phosphorylases family 2 n=1 Tax=marine gamma pro...   207   3e-52
UniRef50_Q09816 Uncharacterized protein C16C9.02c n=49 Tax=cellu...   206   6e-52
UniRef50_A2QWR2 Contig An11c0240, complete genome n=24 Tax=Leoti...   205   9e-52
UniRef50_A4X3Q9 Methylthioadenosine phosphorylase n=8 Tax=Actino...   205   1e-51
UniRef50_B3RV47 Putative uncharacterized protein n=1 Tax=Trichop...   205   1e-51
UniRef50_B5YKP5 S-methyl-5-thioadenosine phosphorylase n=1 Tax=T...   204   2e-51
UniRef50_Q2BRI1 Methylthioadenosine phosphorylase n=1 Tax=Neptun...   203   3e-51
UniRef50_Q5KPU2 Glutamate biosynthesis-related protein, putative...   203   4e-51
UniRef50_C3Y9W3 Putative uncharacterized protein n=1 Tax=Branchi...   203   6e-51
UniRef50_Q1PVD3 Similar to 5'-methylthioadenosine phosphorylase ...   202   8e-51
UniRef50_C1C2B0 S-methyl-5-thioadenosine phosphorylase n=2 Tax=C...   201   2e-50
UniRef50_C1SHM5 Purine nucleoside phosphorylase n=1 Tax=Denitrov...   201   2e-50
UniRef50_A4AL37 5'-methylthioadenosine phosphorylase n=3 Tax=Act...   200   3e-50
UniRef50_B8KGW0 Purine phosphorylase, family 2 n=1 Tax=gamma pro...   200   5e-50
UniRef50_Q07938 Multicopy enhancer of UAS2 n=12 Tax=Saccharomyce...   200   6e-50
UniRef50_B8NP67 5'-methylthioadenosine phosphorylase (Meu1), put...   199   7e-50
UniRef50_A0YHC5 Methylthioadenosine phosphorylase n=1 Tax=marine...   199   9e-50
UniRef50_C5C002 Methylthioadenosine phosphorylase n=37 Tax=Actin...   195   1e-48
UniRef50_Q2S4Q1 Purine nucleoside phosphorylase I, inosine and g...   195   1e-48
UniRef50_C2KQL7 Possible purine-nucleoside phosphorylase n=2 Tax...   194   2e-48
UniRef50_B5ICA6 Phosphorylases family 2 n=2 Tax=Aciduliprofundum...   194   3e-48
UniRef50_C9ZU87 Methylthioadenosine phosphorylase, putative n=8 ...   194   3e-48
UniRef50_Q7TP15 Cc1-6 n=9 Tax=Coelomata RepID=Q7TP15_RAT              193   8e-48
UniRef50_Q1CZV1 Phosphorylase, family 2 n=5 Tax=Myxococcaceae Re...   192   1e-47
UniRef50_B8P408 Predicted protein n=2 Tax=Agaricomycetes RepID=B...   189   7e-47
UniRef50_A7BPC6 Purine phosphorylase, family 2 n=2 Tax=Gammaprot...   188   2e-46
UniRef50_C3ZRU9 Putative uncharacterized protein n=1 Tax=Branchi...   186   7e-46
UniRef50_O28486 Methylthioadenosine phosphorylase (MtaP) n=1 Tax...   186   8e-46
UniRef50_A0B8I0 Methylthioadenosine phosphorylase n=1 Tax=Methan...   185   2e-45
UniRef50_A6GFX4 Purine nucleoside phosphorylase n=1 Tax=Plesiocy...   184   2e-45
UniRef50_UPI00016C3D31 inosine guanosine and xanthosine phosphor...   182   1e-44
UniRef50_D0JB48 Purine nucleoside phosphorylase n=2 Tax=Blattaba...   181   2e-44
UniRef50_Q0SDK3 Probable S-methyl-5-thioadenosine phosphorylase ...   181   2e-44
UniRef50_B0TI52 Purine nucleoside phosphorylase n=8 Tax=Clostrid...   180   4e-44
UniRef50_A0L8V4 Methylthioadenosine phosphorylase n=1 Tax=Magnet...   180   5e-44
UniRef50_C1YKP8 Inosine guanosine and xanthosine phosphorylase f...   177   3e-43
UniRef50_Q11FN7 Methylthioadenosine phosphorylase n=1 Tax=Chelat...   174   2e-42
UniRef50_UPI0000164ED7 purine nucleoside phosphorylase n=1 Tax=H...   173   7e-42
UniRef50_A2VPA1 Purine nucleoside phosphorylase deoD n=1 Tax=Myc...   171   2e-41
UniRef50_Q2FR33 Methylthioadenosine phosphorylase n=1 Tax=Methan...   170   4e-41
UniRef50_Q0CL04 Purine nucleoside phosphorylase n=1 Tax=Aspergil...   170   4e-41
UniRef50_B1ZY09 Purine phosphorylase family 2 n=2 Tax=Opitutacea...   169   7e-41
UniRef50_Q5C0P1 SJCHGC05230 protein (Fragment) n=1 Tax=Schistoso...   168   2e-40
UniRef50_Q9RIJ1 Purine nucleoside phosphorylase homolog (Fragmen...   168   2e-40
UniRef50_C9KQI5 Phosphorylase, family 2 n=1 Tax=Mitsuokella mult...   166   7e-40
UniRef50_Q2RHE2 Purine phosphorylase, family 2 n=1 Tax=Moorella ...   165   1e-39
UniRef50_A9B0Q9 Purine phosphorylase family 2 n=1 Tax=Herpetosip...   163   6e-39
UniRef50_A7BDZ0 Putative uncharacterized protein n=1 Tax=Actinom...   163   7e-39
UniRef50_Q2LVG5 Phosphorylase family 2 protein n=1 Tax=Syntrophu...   161   2e-38
UniRef50_B3PJG7 Methylthioadenosine phosphorylase n=1 Tax=Cellvi...   161   2e-38
UniRef50_D1J9Q0 Putative uncharacterized protein n=2 Tax=uncultu...   161   2e-38
UniRef50_C0W926 Purine-nucleoside phosphorylase n=1 Tax=Actinomy...   160   4e-38
UniRef50_A4IXW9 Phosphorylase family 2/alpha-beta hydrolase fold...   160   5e-38
UniRef50_C7DHY9 S-methyl-5-thioadenosine phosphorylase n=1 Tax=C...   157   4e-37
UniRef50_A2SSB6 Methylthioadenosine phosphorylase n=2 Tax=Methan...   157   4e-37
UniRef50_UPI0001C31DF7 S-methyl-5''''-thioadenosine phosphorylas...   155   1e-36
UniRef50_B5JG81 Phosphorylases family 2 n=1 Tax=Verrucomicrobiae...   150   5e-35
UniRef50_Q67R93 Methylthioadenosine phosphorylase n=1 Tax=Symbio...   149   1e-34
UniRef50_A8RJ25 Putative uncharacterized protein n=1 Tax=Clostri...   148   1e-34
UniRef50_UPI0000D5796F PREDICTED: similar to purine nucleoside p...   146   7e-34
UniRef50_Q9RKG9 Putative phosphorylase n=1 Tax=Streptomyces coel...   143   6e-33
UniRef50_D0NYY4 Putative uncharacterized protein n=1 Tax=Phytoph...   142   1e-32
UniRef50_A7I6C4 Purine phosphorylase, family 2 n=2 Tax=Genera in...   140   8e-32
UniRef50_Q4P1A5 Putative uncharacterized protein n=1 Tax=Ustilag...   136   7e-31
UniRef50_UPI0000E4A236 PREDICTED: similar to GTP-binding protein...   136   9e-31
UniRef50_UPI00016A8371 5''''-methylthioadenosine phosphorylase n...   131   2e-29
UniRef50_B9K7V5 Purine nucleoside phosphorylase n=1 Tax=Thermoto...   130   6e-29
UniRef50_UPI0001926077 PREDICTED: similar to nucleoside phosphor...   129   9e-29
UniRef50_C1HCE7 Purine nucleoside phosphorylase n=1 Tax=Paracocc...   129   1e-28
UniRef50_Q2S0L6 5'-methylthioadenosine phosphorylase II n=1 Tax=...   120   4e-26
UniRef50_C5KDS7 Methylthioadenosine/purine nucleoside phosphoryl...   117   5e-25
UniRef50_C8SNV7 Purine or other phosphorylase family 1 n=2 Tax=M...   112   1e-23
UniRef50_Q67R94 Methylthioadenosine phosphorylase n=1 Tax=Symbio...   112   2e-23
UniRef50_P23139 Uncharacterized 25.8 kDa protein in petC 3'regio...   100   5e-20
UniRef50_C0W509 Possible purine-nucleoside phosphorylase n=1 Tax...   100   6e-20
UniRef50_C0QJ87 Putative purine nucleoside phosphorylase n=1 Tax...    96   2e-18
UniRef50_A9WPZ3 5'-methylthioadenosine phosphorylase n=1 Tax=Ren...    95   2e-18
UniRef50_D1AJ63 Purine or other phosphorylase family 1 n=3 Tax=B...    94   5e-18
UniRef50_UPI000038263C COG0005: Purine nucleoside phosphorylase ...    92   2e-17
UniRef50_A0LI68 Purine and other phosphorylases, family 1 n=1 Ta...    89   2e-16
UniRef50_A4GI77 Possible methylthioadenosine phosphorylase n=1 T...    88   2e-16
UniRef50_A9B0R0 Methylthioadenosine phosphorylase n=1 Tax=Herpet...    87   6e-16
UniRef50_Q9ZMY2 MTA/SAH nucleosidase n=19 Tax=Proteobacteria Rep...    87   7e-16
UniRef50_A6Q4A9 5'-methylthioadenosine nucleosidase/S-adenosylho...    85   2e-15
UniRef50_A0RR16 MTA/SAH nucleosidase n=2 Tax=Campylobacter RepID...    84   5e-15
UniRef50_C8QZD7 Purine or other phosphorylase family 1 n=1 Tax=D...    82   2e-14
UniRef50_A9WPZ4 5'-methylthioadenosine phosphorylase n=1 Tax=Ren...    80   6e-14

Sequences not found previously or not previously below threshold:

>UniRef50_P77834 Purine nucleoside phosphorylase 1 n=41 Tax=Bacilli RepID=PUNA_BACST
          Length = 274

 Score =  349 bits (897), Expect = 4e-95,   Method: Composition-based stats.
 Identities = 120/269 (44%), Positives = 164/269 (60%), Gaps = 1/269 (0%)

Query: 9   NPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGE 68
                   +K   P  +P++  ILGSGLG LAD+IE A+ I Y  +P FPVSTV GHAG+
Sbjct: 5   AIEQAAQFLKEKFP-TSPQIGLILGSGLGVLADEIEQAIKIPYSDIPNFPVSTVEGHAGQ 63

Query: 69  LVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAG 128
           LV G L+G  VV M+GR H+YEG     +T  +R  K LG E L  TNAAG +      G
Sbjct: 64  LVYGQLEGATVVVMQGRFHYYEGYSFDKVTFPVRVMKALGVEQLIVTNAAGGVNESFEPG 123

Query: 129 SLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVF 188
            L+ + DHIN M G P++G ND   G RF  ++ AY    R L + VA + G  + EGV+
Sbjct: 124 DLMIISDHINNMGGNPLIGPNDSALGVRFPDMSEAYSKRLRQLAKDVANDIGLRVREGVY 183

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK 248
           V+  GP +ET AEIRM++++GGD VGMS VPEVI ARH  ++V+ +S I+NMA G+ D  
Sbjct: 184 VANTGPAYETPAEIRMIRVMGGDAVGMSTVPEVIVARHAGMEVLGISCISNMAAGILDQP 243

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKIA 277
           L+H + +   E  K +F+  +   +R +A
Sbjct: 244 LTHDEVIETTEKVKADFLRFVKAIVRNMA 272


>UniRef50_Q2B6A0 Purine nucleoside phosphorylase n=12 Tax=Bacilli RepID=Q2B6A0_9BACI
          Length = 273

 Score =  346 bits (887), Expect = 6e-94,   Method: Composition-based stats.
 Identities = 117/263 (44%), Positives = 162/263 (61%), Gaps = 1/263 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
               +K    + TP++  ILGSGLG LAD+IE  V I Y ++P FPVSTV GHAG+LV G
Sbjct: 9   AAQFLKEKYGE-TPKIGLILGSGLGVLADEIEQPVKIPYNEIPDFPVSTVEGHAGQLVFG 67

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L GV  V M+GR H+YEG     +T  +R  K LG E+L  TNAAG +      G L+ 
Sbjct: 68  LLNGVQAVAMQGRFHYYEGYSFDKVTFPVRVMKELGVEILIVTNAAGGVNESFAPGDLML 127

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN M   P++G ND + G RF  ++ AY  + R   +++A +    + EGV+V   
Sbjct: 128 ISDHINNMGSNPLIGPNDSKLGVRFPDMSEAYSRDLRQQAREIAGKLNISIQEGVYVGNT 187

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP +ET AE+RM++ +GGD VGMS VPEVI ARH  LKV+ +S I+NMA G+ D  L+H 
Sbjct: 188 GPTYETPAEVRMLRTMGGDAVGMSTVPEVIVARHAGLKVLGISCISNMAAGILDQPLNHE 247

Query: 253 QTLAAAELSKQNFINLICGFLRK 275
           + +   E  K NF++ +   +R+
Sbjct: 248 EVIETTEKVKANFLSYVKELVRQ 270


>UniRef50_Q65HU0 PunA n=9 Tax=Firmicutes RepID=Q65HU0_BACLD
          Length = 271

 Score =  345 bits (886), Expect = 8e-94,   Method: Composition-based stats.
 Identities = 125/271 (46%), Positives = 165/271 (60%), Gaps = 1/271 (0%)

Query: 6   FSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH 65
                    D IK+ K +  P V  ILGSGLG LAD+IE+AV I YE +P FPVSTV GH
Sbjct: 1   MKQMIANAADYIKS-KTEIKPAVGLILGSGLGVLADEIEDAVRIKYEDIPDFPVSTVEGH 59

Query: 66  AGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
           AG+LV+G L+ V VV M+GR HFYEG  M  +T  +R  K LG E L  TNAAG +    
Sbjct: 60  AGQLVIGRLENVQVVAMQGRFHFYEGYSMDKVTFPVRVMKELGIETLIVTNAAGGVNESF 119

Query: 126 GAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE 185
             G L+ + DHIN M   P++G ND   G RF  +++AYD E R L +K A+E    + E
Sbjct: 120 RPGDLMIISDHINYMGTNPLIGPNDSSLGVRFPDMSSAYDKELRLLAKKTAEELNISVQE 179

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           GV+ +  GP +ET AE+R ++ IG D VGMS VPEVI A+H  L+V+ +S I+N A G+ 
Sbjct: 180 GVYTAVTGPTYETPAEVRFLRTIGSDAVGMSTVPEVIVAKHAGLRVLGISCISNAAAGIL 239

Query: 246 DVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           D  LSH + +   E  K +F+  +   + KI
Sbjct: 240 DQPLSHDEVIEVTEKVKADFLRFVKAAVAKI 270


>UniRef50_P46354 Purine nucleoside phosphorylase 1 n=69 Tax=Bacteria
           RepID=PUNA_BACSU
          Length = 271

 Score =  344 bits (883), Expect = 2e-93,   Method: Composition-based stats.
 Identities = 120/263 (45%), Positives = 169/263 (64%), Gaps = 1/263 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
               IK   P+ +P++  ILGSGLG LAD+IEN V + YE +P FPVSTV GHAG+LVLG
Sbjct: 8   AAAFIKQNLPE-SPKIGLILGSGLGILADEIENPVKLKYEDIPEFPVSTVEGHAGQLVLG 66

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L+GV V+ M+GR HFYEG  M  +T  +R  K LG E L  TNAAG +  E  AG L+ 
Sbjct: 67  TLEGVSVIAMQGRFHFYEGYSMEKVTFPVRVMKALGVEALIVTNAAGGVNTEFRAGDLMI 126

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN M   P++G N+  FG RF  +++AYD +  +L +K+AK+   P+ +GV+ +  
Sbjct: 127 ITDHINFMGTNPLIGPNEADFGARFPDMSSAYDKDLSSLAEKIAKDLNIPIQKGVYTAVT 186

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP++ET AE+R ++ +G D VGMS VPEVI A H  ++V+ +S I+N A G+ D  LSH 
Sbjct: 187 GPSYETPAEVRFLRTMGSDAVGMSTVPEVIVANHAGMRVLGISCISNAAAGILDQPLSHD 246

Query: 253 QTLAAAELSKQNFINLICGFLRK 275
           + +   E  K  F+ L+   + +
Sbjct: 247 EVMEVTEKVKAGFLKLVKAIVAQ 269


>UniRef50_A7GSB0 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=114 Tax=Bacteria RepID=A7GSB0_BACCN
          Length = 273

 Score =  342 bits (877), Expect = 9e-93,   Method: Composition-based stats.
 Identities = 123/264 (46%), Positives = 168/264 (63%), Gaps = 1/264 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
               +K      TP+V  ILGSGLG LAD+IENAV + Y ++P FPVSTV GHAG+LV G
Sbjct: 9   SATYLKEKF-QETPKVGLILGSGLGVLADEIENAVKVPYSEIPEFPVSTVEGHAGQLVFG 67

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            LQGV VV M+GR H+YEG  M  +T  +R  K LG E +  TNAAG +      G L+ 
Sbjct: 68  TLQGVTVVAMQGRFHYYEGYDMQKVTFPVRVMKELGVETVVVTNAAGGVNTSFEPGDLML 127

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN M   P++G ND   G RF  ++ +Y  E R ++++VA+E    + EGV+V+  
Sbjct: 128 ISDHINFMGHNPLIGPNDAEMGVRFPDMSESYTKELRVMVKQVAEELNIKVQEGVYVAMT 187

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP +ET AEIRM++ +GGD VGMS VPEVI ARH  +KV+ +S I+NMA G+ D  L H 
Sbjct: 188 GPVYETPAEIRMLRTLGGDAVGMSTVPEVIVARHAGMKVLGISCISNMAAGILDQPLHHD 247

Query: 253 QTLAAAELSKQNFINLICGFLRKI 276
           + +   E  K NF+ L+   ++++
Sbjct: 248 EVIETTERVKANFLALVKAIVKQM 271


>UniRef50_C1F7J2 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Acidobacterium capsulatum ATCC 51196
           RepID=C1F7J2_ACIC5
          Length = 284

 Score =  334 bits (858), Expect = 2e-90,   Method: Composition-based stats.
 Identities = 110/277 (39%), Positives = 163/277 (58%), Gaps = 1/277 (0%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           MS +      +     I+   P   P+VA +LGSGLGA A  + N+  + + + P FPVS
Sbjct: 1   MSSLSIFSETIEATACIRKRSP-LQPKVAVVLGSGLGAFAGSLTNSKCMRFSEAPHFPVS 59

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
            V GH+G + +G     PV+ M+GR H YEG   + +   +R  K LG E +  TNAAG 
Sbjct: 60  NVQGHSGRIHIGQCGDTPVLVMQGRVHAYEGYKPSQVAFPVRVMKQLGIEQVIVTNAAGG 119

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           +R  +  G LV ++DHIN     P+ G+N++RFG RFF + NAY    R L   VA++ G
Sbjct: 120 IREGLQPGELVLIEDHINLTGYNPLCGVNEERFGPRFFDMTNAYSPRLRKLAHSVAEQHG 179

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
             L EGV++   GP+FET AEIR  + +G D+VGMS V EVI+ARH  L+V+ +S +TN+
Sbjct: 180 HSLKEGVYIGVLGPSFETPAEIRAFRSMGADLVGMSTVQEVIAARHMGLEVLGISCVTNL 239

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           A GL + +L+H + L   + ++     L+ G + ++A
Sbjct: 240 AAGLQNEELTHEEVLETGKRTEAQLTQLLQGVIPQMA 276


>UniRef50_B1YM96 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=8 Tax=Bacteria RepID=B1YM96_EXIS2
          Length = 270

 Score =  333 bits (855), Expect = 3e-90,   Method: Composition-based stats.
 Identities = 117/258 (45%), Positives = 162/258 (62%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
             K    P +  ILGSGLG LAD IEN +AI Y  +P FPVSTV GHAG+LV G L+G  
Sbjct: 13  ESKMQAKPEIGLILGSGLGVLADDIENPIAIPYSDIPNFPVSTVEGHAGQLVFGTLEGKQ 72

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           VV M+GR HFYEG  M ++T  +R  K +G E L  TNAAG+       G L+ + DHIN
Sbjct: 73  VVAMQGRFHFYEGYSMEMVTFPVRVMKAIGVETLIVTNAAGACNEAFEPGDLMLITDHIN 132

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFET 198
                P++G N D  G RF  ++  YDAE   L Q+ A E G  + +GV+    GP +ET
Sbjct: 133 FFGTNPLIGKNVDEMGPRFPDMSKPYDAELLRLAQETADELGINVRQGVYFGNTGPTYET 192

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
            AE+++ +++GGDVVGMS VPEVI ARH D++V+ +S ++NMA G+ D  L H + +   
Sbjct: 193 PAEVKLARLLGGDVVGMSTVPEVIVARHSDMRVLGISCVSNMAAGILDQPLHHDEVIETT 252

Query: 259 ELSKQNFINLICGFLRKI 276
           E  + +F++L+ G ++K+
Sbjct: 253 ERVRAHFLSLVRGSIKKM 270


>UniRef50_A3DEQ4 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=8 Tax=Firmicutes RepID=A3DEQ4_CLOTH
          Length = 275

 Score =  331 bits (848), Expect = 2e-89,   Method: Composition-based stats.
 Identities = 110/269 (40%), Positives = 158/269 (58%), Gaps = 1/269 (0%)

Query: 6   FSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH 65
                      IK      TP +A +LGSGLG LAD+IEN V I Y+ +P FPV+TV GH
Sbjct: 4   IYEKARETASFIK-RIIKETPEIAIVLGSGLGPLADEIENKVEIDYKDVPNFPVTTVEGH 62

Query: 66  AGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
           AG+ V G L+   V+ MKGR H YEG  ++ +   +R FK+LG   L  TNA+G +    
Sbjct: 63  AGKFVYGILENRRVIAMKGRFHHYEGYDVSQIVFPVRVFKMLGINNLIVTNASGGINRSF 122

Query: 126 GAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE 185
             G L+ +KDHI+    +P+ G N D FG RF  +  AY+ +   + +K A + G  + E
Sbjct: 123 RPGDLMIIKDHISFFAPSPLRGKNIDEFGLRFPDMCKAYNPKLVEICKKAASDVGVDVKE 182

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           GV+    GP +ET AEIR + I+G D VGMS VPEVI+ARH ++ ++ +S ITNMA G+ 
Sbjct: 183 GVYAFTQGPMYETPAEIRALGILGADAVGMSTVPEVIAARHANMNILGISCITNMAAGIL 242

Query: 246 DVKLSHAQTLAAAELSKQNFINLICGFLR 274
           D  L+H + +  A+ ++  F+ L+   + 
Sbjct: 243 DQPLTHEEVMKTAKEAENKFVRLVKRVIS 271


>UniRef50_P45563 Xanthosine phosphorylase n=57 Tax=cellular organisms
           RepID=XAPA_ECOLI
          Length = 277

 Score =  328 bits (840), Expect = 2e-88,   Method: Composition-based stats.
 Identities = 277/277 (100%), Positives = 277/277 (100%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS
Sbjct: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS
Sbjct: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG
Sbjct: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
           FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM
Sbjct: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA
Sbjct: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277


>UniRef50_A9KIZ4 Inosine guanosine and xanthosine phosphorylase family n=6
           Tax=cellular organisms RepID=A9KIZ4_CLOPH
          Length = 274

 Score =  326 bits (835), Expect = 7e-88,   Method: Composition-based stats.
 Identities = 104/271 (38%), Positives = 151/271 (55%), Gaps = 1/271 (0%)

Query: 6   FSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH 65
                +     I++ K +  P+V  +LGSGLG L D IE    ISYE +P FP STV GH
Sbjct: 4   MYDKVMESTKYIQS-KNNLKPKVGVVLGSGLGDLIDVIEEIEYISYEDIPNFPKSTVIGH 62

Query: 66  AGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
            G LV G + GV ++ M+GR H++EG  M  +   I   K LG E L  TNA G +  + 
Sbjct: 63  QGRLVFGKINGVDILAMQGRFHYFEGYTMKEVAYPIFVMKQLGIEQLILTNACGGINTDF 122

Query: 126 GAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE 185
             G+L+ + D IN +   P++G+ND+RFG RF  ++  Y  +     + +A E G    E
Sbjct: 123 QPGTLMIINDFINLVSDNPLIGVNDERFGTRFPDMSEPYKLDLIDKAKNIANEMGIEYKE 182

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           GV+  + GP +ETAAEIRM++  G D VGMS VPE I+A +  + V+ +S ITNMA G+ 
Sbjct: 183 GVYAGFMGPYYETAAEIRMIKNHGADAVGMSTVPETIAANYLGIDVLGISCITNMATGIQ 242

Query: 246 DVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
             K SH + +  A+ +  N    +   +  +
Sbjct: 243 KHKHSHERVVETAQKASVNLSKWVAKIIENM 273


>UniRef50_B5R3U9 Xanthosine phosphorylase n=53 Tax=Enterobacteriaceae
           RepID=B5R3U9_SALEP
          Length = 307

 Score =  324 bits (831), Expect = 2e-87,   Method: Composition-based stats.
 Identities = 246/277 (88%), Positives = 258/277 (93%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           M    FSHNP +CIDII  +KP FTPRVAFILGSGLGALADQIE+AVAISYEKLPGFPVS
Sbjct: 31  MPHALFSHNPEYCIDIIHAHKPAFTPRVAFILGSGLGALADQIEDAVAISYEKLPGFPVS 90

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           TVHGHAGELVLGHL GVPV CMKGRGHFYEGRGM +MTDAIRT KLLGCE+LFCTNAAGS
Sbjct: 91  TVHGHAGELVLGHLAGVPVACMKGRGHFYEGRGMAVMTDAIRTLKLLGCEVLFCTNAAGS 150

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           LRPEVG GSLVAL DHINTMPGTPMVG NDDR+G+RFFSLANAYDA+YRA+LQ VA EEG
Sbjct: 151 LRPEVGPGSLVALSDHINTMPGTPMVGPNDDRYGDRFFSLANAYDADYRAMLQSVAAEEG 210

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
           FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHC LKVVAVSAITN+
Sbjct: 211 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCGLKVVAVSAITNL 270

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           AEGL DVKLSHAQTLAAAELS+QNFINLICGFLRK+A
Sbjct: 271 AEGLGDVKLSHAQTLAAAELSRQNFINLICGFLRKLA 307


>UniRef50_Q23U21 Purine nucleoside phosphorylase n=1 Tax=Tetrahymena thermophila
           SB210 RepID=Q23U21_TETTH
          Length = 274

 Score =  321 bits (824), Expect = 1e-86,   Method: Composition-based stats.
 Identities = 97/270 (35%), Positives = 155/270 (57%)

Query: 7   SHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHA 66
             + L     IK+   +  P++A +LGSGLG   D+I++ + I Y  +P F  + V GHA
Sbjct: 4   YKSALEATQFIKSKINNLNPQIAIVLGSGLGNFGDEIQDKIEIPYGDIPHFKKTQVIGHA 63

Query: 67  GELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVG 126
           G+L+ G ++GV +VCM+GR HFYEG  +      I+ FKLL  ++L  TNAAG L     
Sbjct: 64  GKLIFGKVEGVEIVCMQGRYHFYEGHTIQECVFPIKVFKLLNIKILILTNAAGGLNDSYE 123

Query: 127 AGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG 186
           +G L+ ++DHIN +   P++GLN++ FG RF  ++  Y  +     +KV K+    +  G
Sbjct: 124 SGDLILIRDHINMLGINPLIGLNEEEFGPRFPDMSITYTPQLLEKAKKVMKDLNISIKTG 183

Query: 187 VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD 246
            +    GPN+ET AE++M++    D+VG S V E I A H +++V+ +S ++NM  G+S 
Sbjct: 184 TYAGLRGPNYETPAEVQMLRTFRADLVGASTVYEAIVASHMNIQVLGISCVSNMGAGISK 243

Query: 247 VKLSHAQTLAAAELSKQNFINLICGFLRKI 276
             LSH + +  +   K  F NL+   +  +
Sbjct: 244 TPLSHQEIIDVSNSIKSKFSNLVKNLIPNL 273


>UniRef50_A6BDL0 Putative uncharacterized protein n=1 Tax=Dorea longicatena DSM
           13814 RepID=A6BDL0_9FIRM
          Length = 270

 Score =  321 bits (823), Expect = 2e-86,   Method: Composition-based stats.
 Identities = 108/271 (39%), Positives = 159/271 (58%), Gaps = 1/271 (0%)

Query: 6   FSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH 65
                  C+  I+  K DF P  A ILGSGLG  A++I+    + Y  +  FPVSTV GH
Sbjct: 1   MYKKLEKCLKSIRE-KTDFKPEKAVILGSGLGDYAEKIKIEKIVKYTDIEDFPVSTVQGH 59

Query: 66  AGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
            G+ V G+++ VPVV M+GR H+YEG  M  +    R   ++G + +  TNAAG + P  
Sbjct: 60  KGQFVFGYVEDVPVVLMQGRVHYYEGYPMQDVVLPTRLMGMMGAKKILLTNAAGGVNPSF 119

Query: 126 GAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE 185
             G  + +KDHI T   +P++G N +  G RF  ++  Y  + + +++K AK+ G PL E
Sbjct: 120 RPGDFMLIKDHITTAVPSPLIGPNIEELGTRFPDMSEVYSKKLQDIIRKSAKDCGIPLQE 179

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           GV+V   GPN+ET AEIRM++  G D VGMS   E ++ARH  ++V  +S ITNMA G+S
Sbjct: 180 GVYVQLTGPNYETPAEIRMVRSWGADAVGMSTACEAMAARHMGMEVCGISCITNMAAGVS 239

Query: 246 DVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           + KL+HA+    A+   ++F  L+   +  I
Sbjct: 240 NAKLNHAEVQETADRVAKDFEKLVTDVIAAI 270


>UniRef50_B9MKK7 Inosine guanosine and xanthosine phosphorylase family n=68
           Tax=Bacteria RepID=B9MKK7_ANATD
          Length = 272

 Score =  321 bits (823), Expect = 2e-86,   Method: Composition-based stats.
 Identities = 111/265 (41%), Positives = 160/265 (60%), Gaps = 1/265 (0%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL 71
              + IK+  P+  P +A ILGSGLG+ AD +E  + I Y ++P FPVSTV GH G LV 
Sbjct: 9   EASEFIKSKIPNV-PEIAIILGSGLGSFADTMEEKIEIKYSEIPHFPVSTVKGHKGNLVF 67

Query: 72  GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
           G ++G  V+  +GR H YEG     +   +R   LLG + L  TNAAG + P +  G L+
Sbjct: 68  GKVKGREVLAFQGRFHLYEGYNAQEVVFGVRAAGLLGVKNLIVTNAAGGISPLLSPGDLM 127

Query: 132 ALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSY 191
            +KDHIN     P +G   ++FGERFF +  AYD E     + V K+ G    EG++   
Sbjct: 128 VIKDHINLSGENPAIGSEAEKFGERFFDMTYAYDREIIEKSKDVYKKNGVDYKEGIYAFL 187

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH 251
            GP++ET +EIRM++I+G D VGMS V EVI+AR  ++KV  +S ITNMA G+ + KLSH
Sbjct: 188 KGPSYETPSEIRMLKILGADAVGMSTVLEVIAARQMNIKVFGISCITNMAAGILEKKLSH 247

Query: 252 AQTLAAAELSKQNFINLICGFLRKI 276
            + +  +++ ++ FI +I   +  I
Sbjct: 248 EEVIEVSKMVEEKFIKIISDLIEII 272


>UniRef50_A5IBS6 Xanthosine phosphorylase n=5 Tax=Legionella RepID=A5IBS6_LEGPC
          Length = 279

 Score =  316 bits (811), Expect = 4e-85,   Method: Composition-based stats.
 Identities = 122/277 (44%), Positives = 170/277 (61%), Gaps = 1/277 (0%)

Query: 2   SQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVST 61
           + +     P    + I+   P F P+V  +LGSGLG  A+++E+ VAI YEKLPGFP +T
Sbjct: 3   TSISTISYPHLAAEYIQKTCPSFKPKVGVVLGSGLGQFAEELEDTVAIEYEKLPGFPRTT 62

Query: 62  VHGHAGELVLGHLQGVPVVCMKGRGHFYEGR-GMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           V GH G+L+LG+     V+C++GR H YE       +   +RT KLLGC+    TNA+GS
Sbjct: 63  VQGHGGKLILGYYGSTAVICLQGRAHTYESMENHEAVKTYVRTLKLLGCQYFIATNASGS 122

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           L+ EVG G L+ + DHIN  PG P+VG NDD FG RF+ L NAYD   R  L  +A+   
Sbjct: 123 LKEEVGPGELMLITDHINFQPGNPLVGPNDDEFGPRFYPLDNAYDITMRNALLDIAQRHS 182

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
             L +GV++S  GPN+ETAAEIR  +++G D VGMS VPEV+ A HC L+V  ++ ITN 
Sbjct: 183 IKLHQGVYISVLGPNYETAAEIRAFKLLGADAVGMSTVPEVLVANHCGLRVAVIATITNY 242

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           A GL+    SH   +  A  + +    LI  ++ +++
Sbjct: 243 ATGLAKTSHSHESVVKMASSAAEKLNTLIKQYILELS 279


>UniRef50_P00491 Purine nucleoside phosphorylase n=19 Tax=Coelomata RepID=PNPH_HUMAN
          Length = 289

 Score =  316 bits (811), Expect = 4e-85,   Method: Composition-based stats.
 Identities = 111/271 (40%), Positives = 151/271 (55%), Gaps = 8/271 (2%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
             + + ++     P+VA I GSGLG L D++  A    Y ++P FP STV GHAG LV G
Sbjct: 13  TAEWLLSH-TKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFG 71

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L G   V M+GR H YEG  +  +T  +R F LLG + L  TNAAG L P+   G ++ 
Sbjct: 72  FLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIML 131

Query: 133 LKDHIN---TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG--FPLTEGV 187
           ++DHIN        P+ G ND+RFG+RF ++++AYD   R       K+ G    L EG 
Sbjct: 132 IRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGT 191

Query: 188 FVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD- 246
           +V   GP+FET AE R++Q +G D VGMS VPEVI ARHC L+V   S ITN      + 
Sbjct: 192 YVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYES 251

Query: 247 -VKLSHAQTLAAAELSKQNFINLICGFLRKI 276
             K +H + LAA + + Q     +   +  I
Sbjct: 252 LEKANHEEVLAAGKQAAQKLEQFVSILMASI 282


>UniRef50_C9LGF9 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Prevotella tannerae ATCC 51259
           RepID=C9LGF9_9BACT
          Length = 291

 Score =  316 bits (810), Expect = 6e-85,   Method: Composition-based stats.
 Identities = 99/274 (36%), Positives = 154/274 (56%), Gaps = 2/274 (0%)

Query: 3   QVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTV 62
            + +        + I+ +     P+ A +LG+GLG LA +I+      Y+ +P FPVSTV
Sbjct: 19  HMTYLAQIQETAEWIQAH-TALRPQTAIVLGTGLGKLAQEIDVVDEFPYKDIPNFPVSTV 77

Query: 63  HGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLR 122
            GH+G L+ GHL G P++ ++GR H+YEG  M  +T   R    LG + LF +NA+G   
Sbjct: 78  EGHSGRLIFGHLGGKPIMALEGRFHYYEGYTMQEVTFPERVMYALGIKNLFLSNASGGTN 137

Query: 123 PEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP 182
           P+   G L+ + DHIN  P  P+ G N    G RF  ++ AYD  +    + +A+E+G  
Sbjct: 138 PDFEIGDLMLITDHINFQPEHPLHGPNIPT-GPRFPDMSEAYDRAFLEAARNIAREKGIK 196

Query: 183 LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAE 242
           + EGV+++  GP +ET AE +M +++G D VGMS VPEVI ARHC ++   +S IT++  
Sbjct: 197 VVEGVYLADQGPTYETPAEYKMYRLLGADAVGMSTVPEVIVARHCGIRCFGISIITDLGV 256

Query: 243 GLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
               V++SH +   AA   +     +    ++KI
Sbjct: 257 EGKIVEVSHEEVQKAANAVQPLMAEIFRELIKKI 290


>UniRef50_B8HVY6 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Cyanothece sp. PCC 7425 RepID=B8HVY6_CYAP4
          Length = 275

 Score =  316 bits (809), Expect = 7e-85,   Method: Composition-based stats.
 Identities = 111/272 (40%), Positives = 159/272 (58%), Gaps = 2/272 (0%)

Query: 5   QFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHG 64
           +         + ++ Y     P +  ILGSGLG+ A  ++ ++AI Y  +P FP  TV G
Sbjct: 3   ELYTQATAAAEFLRQY--QIMPDIWVILGSGLGSFASTLKKSLAIPYADIPHFPRPTVAG 60

Query: 65  HAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPE 124
           H GEL+LG    + V  M+GR H+YEG  +  +T  IR   LLG + L  TNAAG L P+
Sbjct: 61  HGGELILGQCGEIAVGVMQGRCHYYEGYSLEQVTFPIRVAGLLGVQRLVITNAAGGLNPD 120

Query: 125 VGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT 184
              G L+ + DHIN +   P+ G ++ RFG+RF  L  AY A YR L  K A E    L 
Sbjct: 121 FVPGDLMLITDHINLLGMNPLQGRHETRFGDRFLDLTQAYHATYRELALKAAAEMNLTLR 180

Query: 185 EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL 244
           +GV+V+ PGP+FET AE+RM++ +GGD VGMS VPEVI  R   ++++ +S ITN+A G+
Sbjct: 181 QGVYVALPGPSFETPAEVRMLRALGGDAVGMSTVPEVIVGRQMGVQILGISCITNLAAGI 240

Query: 245 SDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           S   ++H + L   E   Q+F  L+   L ++
Sbjct: 241 SSEPVNHTEVLEVGEQVSQHFCELLQRTLPRL 272


>UniRef50_A6NWZ5 Putative uncharacterized protein n=1 Tax=Bacteroides capillosus
           ATCC 29799 RepID=A6NWZ5_9BACE
          Length = 274

 Score =  315 bits (808), Expect = 8e-85,   Method: Composition-based stats.
 Identities = 108/271 (39%), Positives = 157/271 (57%)

Query: 6   FSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH 65
                    + I++   DFTP+ A +LGSGLG + D +++ + + Y+++P F  ST  GH
Sbjct: 4   TFAQYQESAEYIRSKIGDFTPKAAMVLGSGLGFMGDVVKDPIVVPYKEIPHFKASTAPGH 63

Query: 66  AGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
            G+LV G+L+  PV  M+GR H YEG     ++ A+R  +LLG + L  TNAAG +R + 
Sbjct: 64  KGQLVFGYLEDKPVAVMQGRMHHYEGYSFEDVSYAVRVLRLLGADTLIVTNAAGCVRTDW 123

Query: 126 GAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE 185
            AG L+ + DHI     +P+ G N   FG RF   ++ Y    R L ++ A E G  L E
Sbjct: 124 QAGDLMLITDHIKMFSESPLRGENMPEFGVRFPDASSLYTPALRTLAREAAAELGIELRE 183

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           GV+    GP +ET AE+R  +I+GGD VGMS  PEVI A HC ++V+  + ++NMA G+ 
Sbjct: 184 GVYFYCYGPQYETPAEVRAARILGGDAVGMSTAPEVIVAGHCGMQVLGFTLLSNMAAGIL 243

Query: 246 DVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           D  LS  + L AAE  K  F  L+   L+K+
Sbjct: 244 DQPLSEQEVLDAAEACKDKFSRLVLACLKKL 274


>UniRef50_P23492 Purine nucleoside phosphorylase n=47 Tax=Metazoa RepID=PNPH_MOUSE
          Length = 289

 Score =  314 bits (806), Expect = 1e-84,   Method: Composition-based stats.
 Identities = 111/283 (39%), Positives = 152/283 (53%), Gaps = 8/283 (2%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           M       +       +  +  ++ P+VA I GSGLG L   ++ A    Y ++P FP S
Sbjct: 1   MENEFTYEDYETTAKWLLQH-TEYRPQVAVICGSGLGGLTAHLKEAQIFDYNEIPNFPQS 59

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           TV GHAG LV G L G   V M+GR H YEG  ++ +T  +R F LLG E L  TNAAG 
Sbjct: 60  TVQGHAGRLVFGLLNGRCCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVETLVVTNAAGG 119

Query: 121 LRPEVGAGSLVALKDHIN---TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAK 177
           L P    G ++ ++DHIN        P+ G ND+RFG RF ++++AYD + R       K
Sbjct: 120 LNPNFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFTAWK 179

Query: 178 EEG--FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVS 235
           + G    L EG +V   GPNFET AE R+++++G D VGMS VPEVI ARHC L+V   S
Sbjct: 180 QMGEQRKLQEGTYVMLAGPNFETVAESRLLKMLGADAVGMSTVPEVIVARHCGLRVFGFS 239

Query: 236 AITNMAEGLSD--VKLSHAQTLAAAELSKQNFINLICGFLRKI 276
            ITN      +   K +H + L A + + Q     +   +  I
Sbjct: 240 LITNKVVMDYENLEKANHMEVLDAGKAAAQTLERFVSILMESI 282


>UniRef50_C7M8V2 Inosine guanosine and xanthosine phosphorylase family n=3
           Tax=Flavobacteriaceae RepID=C7M8V2_CAPOD
          Length = 275

 Score =  314 bits (805), Expect = 2e-84,   Method: Composition-based stats.
 Identities = 109/270 (40%), Positives = 155/270 (57%)

Query: 5   QFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHG 64
           Q          II++Y  + TP  A ILGSGL  L D++E    I Y  +P FP STV G
Sbjct: 3   QVYDKINETARIIQSYITEHTPEFAIILGSGLNKLEDEVEVISEIKYNNIPNFPKSTVEG 62

Query: 65  HAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPE 124
           H G+L+ G ++   V+ M GR H+YEG  M  +T  IR F  LG + L  +NA+G + P 
Sbjct: 63  HKGKLIYGKIENRYVLMMAGRVHYYEGYTMQEVTFPIRVFAQLGIKRLIVSNASGGVNPN 122

Query: 125 VGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT 184
              G ++ ++DHIN  P  P+ G N D FG RF  ++  Y       L+K+AK+    L 
Sbjct: 123 FSIGDVMVIRDHINLFPEHPLRGKNLDLFGARFPDMSKPYSQAMITELEKIAKKHKIKLQ 182

Query: 185 EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL 244
           +GV+V   GP+FET AE  M++I+GGD VGMS VPEVI ARH +++V A+S IT++    
Sbjct: 183 KGVYVGLQGPSFETPAEYGMVRILGGDAVGMSTVPEVIVARHQNMEVCALSVITDLGGPD 242

Query: 245 SDVKLSHAQTLAAAELSKQNFINLICGFLR 274
               +SH + L AA ++  N I L+   ++
Sbjct: 243 ISPDVSHEEVLNAANIAMPNVILLVKNLIK 272


>UniRef50_Q3B5L6 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=48 Tax=Bacteria RepID=Q3B5L6_PELLD
          Length = 302

 Score =  314 bits (804), Expect = 3e-84,   Method: Composition-based stats.
 Identities = 98/266 (36%), Positives = 143/266 (53%), Gaps = 1/266 (0%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
              +  I+    D  P V  +LG+GLGALA +I+   A+ Y  +P FP+STV  H G+L+
Sbjct: 38  EEAVSFIRKKTQDEYP-VGIVLGTGLGALAKEIDVEFALDYADIPNFPISTVETHHGKLI 96

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
            G L G  VV M+GR HFYEG  M  +   IR  K LG + L  TNA G L P    G +
Sbjct: 97  FGTLAGRKVVAMQGRFHFYEGYSMQQIVFPIRVMKHLGVKTLGITNACGGLNPGFQKGDI 156

Query: 131 VALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVS 190
           + + DHIN +PG P++G ND   G RF  +   Y      + ++VA E    +  GV+++
Sbjct: 157 MLIDDHINMLPGNPLIGHNDPETGSRFPDMCEPYSKRLLKIAEEVALEHKIKVQRGVYIA 216

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
             GP  ET AE RM++ +G DVVGMS VPEVI+A H   +V  +S IT+     +   +S
Sbjct: 217 LSGPCLETRAEYRMLRTLGADVVGMSTVPEVIAAVHQGTEVFGMSIITDECFPDNLHPVS 276

Query: 251 HAQTLAAAELSKQNFINLICGFLRKI 276
             + +  +  ++     +    + K+
Sbjct: 277 IEEIIEVSNHAEPKMTTIFKNVVAKL 302


>UniRef50_A9KIE8 Inosine guanosine and xanthosine phosphorylase family n=20
           Tax=Bacteria RepID=A9KIE8_CLOPH
          Length = 286

 Score =  312 bits (800), Expect = 7e-84,   Method: Composition-based stats.
 Identities = 103/259 (39%), Positives = 154/259 (59%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
             K +F P VA +LGSGLG  ADQI+    + Y ++ GFPVSTV GH G  V G+++ VP
Sbjct: 22  QRKINFKPFVALVLGSGLGDYADQIKVEATLDYNEIEGFPVSTVAGHKGRFVFGYVEEVP 81

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           VV M+GR H+YEG  M  +    R  K++G ++LF TNAAG +     AG  + + D I+
Sbjct: 82  VVIMQGRVHYYEGYEMEDVVLPTRLMKMMGAKVLFLTNAAGGVNFNFKAGDFMLITDQIS 141

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFET 198
               +P++G N +  G RF  ++  YD + R +++  AK+ G  L EGV++   GPNFE+
Sbjct: 142 NFVPSPLIGPNIEELGLRFCDMSEVYDKDLREVIRNSAKDIGMELQEGVYIQLSGPNFES 201

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
            AE++M +++G D VGMS   E I+A H  +K+  +S I+N+  G+++  LSH +    A
Sbjct: 202 PAEVKMCRLLGADAVGMSTACEAITANHMGMKICGISCISNLGCGMTEEPLSHIEVQETA 261

Query: 259 ELSKQNFINLICGFLRKIA 277
           +     F  LI   +R IA
Sbjct: 262 DRVAPLFKQLITTSIRNIA 280


>UniRef50_Q1IM44 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=2 Tax=cellular organisms RepID=Q1IM44_ACIBL
          Length = 280

 Score =  312 bits (800), Expect = 8e-84,   Method: Composition-based stats.
 Identities = 118/277 (42%), Positives = 167/277 (60%), Gaps = 1/277 (0%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           M + +      +    I +  P   P VA +LGSGLG  A+++     I + ++P FPVS
Sbjct: 1   MLKPEAFLQAEYAARFIGSKCP-VRPNVAVVLGSGLGDFANELAQPSTIPFGEIPHFPVS 59

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           T  GHAG LV+G+  G+ +  M+GR HFYEG         +R    LG + +  TNAAG 
Sbjct: 60  TAIGHAGNLVIGNFVGLSLAVMQGRAHFYEGNTFAQAAFPMRVLHQLGVKAVVLTNAAGG 119

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           + P+ G G+LV ++DHIN M G+P++G NDDRFG RF  +  AYD EYR + +  AK   
Sbjct: 120 INPQYGRGALVMVRDHINMMGGSPLIGPNDDRFGPRFPDMTYAYDREYRKIAEAEAKRLD 179

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
            P  EG++ +  GP++ET AEI+M+  +G D+VGMS VPEVI ARH D++V+A+S +TNM
Sbjct: 180 IPYYEGIYAAMHGPSYETPAEIQMLARMGADLVGMSTVPEVIVARHMDVRVLAISCVTNM 239

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           A GLS   ++H + L      K  F+ L+   L KIA
Sbjct: 240 AAGLSGEAINHEEVLETGRRVKDTFLALLRAVLPKIA 276


>UniRef50_D0LL71 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Haliangium ochraceum DSM 14365
           RepID=D0LL71_HALO1
          Length = 275

 Score =  312 bits (799), Expect = 1e-83,   Method: Composition-based stats.
 Identities = 101/261 (38%), Positives = 146/261 (55%)

Query: 16  IIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQ 75
           +++    D  P+V  ILGSGLG+ AD++E+AV++ + ++P    ST  GHAG LV G   
Sbjct: 1   MLRERLGDRKPQVGLILGSGLGSFADELEDAVSVPFGEVPHVLPSTAPGHAGRLVCGTRA 60

Query: 76  GVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKD 135
           GV  + M+GR H YEG      T  +R    LG   L  TNAAG +  +   G+ + ++D
Sbjct: 61  GVSCIVMQGRLHLYEGHPAADATFPVRCMIALGARTLLVTNAAGGMHGDWEPGTFMLIRD 120

Query: 136 HINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPN 195
           HIN M   P+ G ND+R G RF  +  AYD   R L  + A E G  L +GV+++  GP 
Sbjct: 121 HINMMHDHPLRGPNDERLGPRFPDMTRAYDPALRELALRAADEVGVSLQQGVYLASTGPT 180

Query: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL 255
           +ET AE+ MM+ +G D  GMS VPEVI ARH   + +  S ITN A G++   L+HA+ +
Sbjct: 181 YETPAEVMMMRGLGADACGMSTVPEVIVARHMGARCLGFSCITNKAAGITGQPLNHAEVM 240

Query: 256 AAAELSKQNFINLICGFLRKI 276
                 +     L+   L ++
Sbjct: 241 ETGARVRSQLTKLLDAVLAEL 261


>UniRef50_B6J4B4 Xanthosine phosphorylase n=8 Tax=Gammaproteobacteria
           RepID=B6J4B4_COXB1
          Length = 273

 Score =  311 bits (797), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 126/262 (48%), Positives = 175/262 (66%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +  I+  +PDF P++A +LGSGLG LAD+IE    ISY +LPGF    + GHAG L LG
Sbjct: 8   ALKEIRHRRPDFQPKLAIVLGSGLGDLADEIEEPTVISYHELPGFHKPNIEGHAGNLYLG 67

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            ++GVPV C++GR H+YEG     +   IRT KLLGCE+   TNAAGSL   +  GSL+ 
Sbjct: 68  KIKGVPVACLRGRAHYYEGADNYAIKTMIRTMKLLGCEIWLATNAAGSLHQRIEPGSLLV 127

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           + DHIN      +VG N+D FG RF  + +AYD++ RA L K+AK+   PL+EGV++   
Sbjct: 128 INDHINFQFNNVLVGPNEDDFGGRFIGMEDAYDSDLRAQLFKIAKQLQIPLSEGVYIGVL 187

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP FET AEIR  +++G DVVGMS +PEVI ARHCD++V  +S ++N A GL+  K++H 
Sbjct: 188 GPAFETPAEIRAFRLLGADVVGMSTIPEVIVARHCDMRVAVISVVSNFAAGLTHEKVTHE 247

Query: 253 QTLAAAELSKQNFINLICGFLR 274
           QTL   +L+ ++   L+  F++
Sbjct: 248 QTLRGVKLATESLKQLVLAFIQ 269


>UniRef50_D0NTD2 Purine nucleoside phosphorylase 1 n=5 Tax=cellular organisms
           RepID=D0NTD2_PHYIN
          Length = 363

 Score =  309 bits (793), Expect = 5e-83,   Method: Composition-based stats.
 Identities = 111/273 (40%), Positives = 150/273 (54%), Gaps = 8/273 (2%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
               D ++       P +  + GSGLG L+  +EN   I YE +P FP STV GHAGELV
Sbjct: 86  DTINDFLQERIT-ARPLIGVVCGSGLGGLSKCLENQEVIKYEDIPQFPRSTVEGHAGELV 144

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
            G L G+ VVCM+GR H YEG  M      IR   LLG + L  TNAAG L P+   G L
Sbjct: 145 FGDLDGIRVVCMRGRFHCYEGYAMRETALPIRVMYLLGIKYLLVTNAAGGLNPDFNVGDL 204

Query: 131 VALKDHINT---MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF--PLTE 185
           + + DH+N        P++G ND RFG RF  L+N YD + + L  KVA++ G    + +
Sbjct: 205 MIMNDHLNMPGLSGQHPLIGPNDSRFGARFTPLSNCYDKKLQDLAVKVAEDLGLTHKVRK 264

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAE--G 243
           GV+    GP +ET  E R ++++G D VGMS VPEVI A HC LKV+ +S ITN A   G
Sbjct: 265 GVYCFVSGPTYETPTECRFLRLVGSDAVGMSTVPEVIVAAHCGLKVIGLSLITNKALFPG 324

Query: 244 LSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
                 SH + L   + ++ +    +   + +I
Sbjct: 325 EEREAASHDEVLETVQATQNDIKRYVRDLIAEI 357


>UniRef50_A6GZM2 Purine-nucleoside phosphorylase n=3 Tax=Bacteroidetes
           RepID=A6GZM2_FLAPJ
          Length = 270

 Score =  309 bits (793), Expect = 5e-83,   Method: Composition-based stats.
 Identities = 106/253 (41%), Positives = 152/253 (60%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           K +F+P    ILGSGLG   D I     + Y ++P FPVSTV GH G LV G +QG  +V
Sbjct: 15  KTNFSPEYGVILGSGLGNFTDDINIEYILPYSEIPNFPVSTVEGHKGALVFGTIQGKKIV 74

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
            M+GR HFYEG  M  +T  +R  K LG E L  +NA+G + P    GS++ +KDHIN M
Sbjct: 75  AMQGRFHFYEGYDMKQVTFPVRVMKYLGVEKLIVSNASGGVNPNYKVGSIILIKDHINMM 134

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAA 200
           P  P+ G ND+RFG RF +++  Y  +     +++A      + +GV++   GP +ET +
Sbjct: 135 PEHPLRGKNDERFGPRFVNMSEPYSRKMIVKAKEIASYLDIQVQDGVYLGLQGPTYETLS 194

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAEL 260
           E +M++ +G D VGMS VPEVI ARH +L+   +S IT+M    S   +SHA+ L AA+ 
Sbjct: 195 EYKMVKNVGADCVGMSTVPEVIVARHMNLECFGLSIITDMGNEASIETVSHAEVLQAAQK 254

Query: 261 SKQNFINLICGFL 273
           ++ +  NLI   +
Sbjct: 255 AEPHVRNLIKELI 267


>UniRef50_Q0TU47 Purine nucleoside phosphorylase n=7 Tax=Clostridium perfringens
           RepID=Q0TU47_CLOP1
          Length = 272

 Score =  309 bits (792), Expect = 6e-83,   Method: Composition-based stats.
 Identities = 106/270 (39%), Positives = 157/270 (58%), Gaps = 1/270 (0%)

Query: 6   FSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH 65
            S       + IK+ K  ++P++  +LG+GLG LA++IE A    Y  +P FPV T+ GH
Sbjct: 3   LSKEIKEAYEYIKS-KSKYSPKIGLVLGTGLGDLANEIEEAEYYRYMDIPNFPVPTIAGH 61

Query: 66  AGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
            G L++G L G  V+ MKGR H+YEG  M  +T  IR  KLLG E L  TN +G  +  +
Sbjct: 62  EGTLIIGKLHGREVIAMKGRCHYYEGHSMQRITLPIRVMKLLGVETLVVTNCSGQAKESI 121

Query: 126 GAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE 185
            AG LV +++HIN     P+ G N   FGERF  LA  YD + R  ++ +AK+    L E
Sbjct: 122 EAGDLVVIRNHINFTGDNPLRGENLLEFGERFPDLAYPYDKDLREEVKNIAKDLDINLKE 181

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           GV+  + GP++ETA E  M   +G DVVGMS VPEVI A HC +KV+  S +  +A   S
Sbjct: 182 GVYAMFSGPSYETAVETLMAASLGADVVGMSTVPEVIVANHCGIKVLGFSGVPCLAAAYS 241

Query: 246 DVKLSHAQTLAAAELSKQNFINLICGFLRK 275
           + +++H + +   +   +   +++  FL++
Sbjct: 242 EAEITHEEAMVNFQSITEKCTSIVKEFLKR 271


>UniRef50_Q95TC1 GH03781p n=13 Tax=cellular organisms RepID=Q95TC1_DROME
          Length = 356

 Score =  309 bits (792), Expect = 6e-83,   Method: Composition-based stats.
 Identities = 112/275 (40%), Positives = 159/275 (57%), Gaps = 10/275 (3%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
               D I T      P++  I GSGLG+LAD I++     YEK+P FPVSTV GHAG LV
Sbjct: 78  EEIADFI-TKGSGMRPKIGIICGSGLGSLADMIQDPKIFEYEKIPNFPVSTVEGHAGRLV 136

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
           +G L+G  V+ M+GR HFYEG  +   +  +R  KL G E LF TNAAG + P    G +
Sbjct: 137 VGTLEGATVMAMQGRFHFYEGYPLAKCSMPVRVMKLCGVEYLFATNAAGGINPRFAVGDI 196

Query: 131 VALKDHIN---TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTE 185
           + + DH+N       +P+ G ND RFG RF +L N+Y+ +      ++AK  G    +  
Sbjct: 197 MLMHDHVNMLGFAGNSPLQGPNDPRFGPRFPALVNSYNKDLINKAIEIAKAMGIESNIHV 256

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAE--- 242
           GV+    GPN+ET AE++ ++++G D VGMS V EVI+ARHCD+KV A S ITN      
Sbjct: 257 GVYSCLGGPNYETIAELKALRMMGVDAVGMSTVHEVITARHCDMKVFAFSLITNKCATEY 316

Query: 243 -GLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
               D + +H + +A A+  ++    L+   +R+I
Sbjct: 317 SDKKDDEANHDEVMAVAKNRQKACCELVSRLIREI 351


>UniRef50_Q6MGR6 Pnp protein n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MGR6_BDEBA
          Length = 280

 Score =  308 bits (790), Expect = 1e-82,   Method: Composition-based stats.
 Identities = 98/266 (36%), Positives = 148/266 (55%), Gaps = 1/266 (0%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
              +  I+T K    P++  +LGSGLGA   ++E    I Y+ +P F   TV GH+G L+
Sbjct: 16  QESMTYIRT-KTSAKPKIGVVLGSGLGAFVKEVEVETTIPYKDIPHFSPPTVEGHSGNLI 74

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
            G + G  +  ++GR H+YEG  M  +    RT  +LG E L  TN+AG     + AG  
Sbjct: 75  FGKINGQSIAILQGRNHYYEGHSMESVVFPTRTLAMLGVETLILTNSAGGFGENMQAGDF 134

Query: 131 VALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVS 190
           + ++DHIN M   P++G N    G RF  +  AYD     +++ V  ++G    +GV+  
Sbjct: 135 MVIEDHINLMGTNPLMGPNIKELGPRFPDMTEAYDKRLIQIMEDVLMKQGTRYHKGVYCG 194

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
             GP +ET +E+R +++IGG  VGMS VPE I+A H  L+V A+S ITN+A G+S  KLS
Sbjct: 195 VSGPTYETPSEVRYLKLIGGKAVGMSTVPETIAANHLGLRVAALSCITNLAAGISSQKLS 254

Query: 251 HAQTLAAAELSKQNFINLICGFLRKI 276
           H +    A+  +  F + +  F+  I
Sbjct: 255 HNEVTETAKQVEMQFSSFLREFIAHI 280


>UniRef50_UPI0000522022 PREDICTED: similar to nucleoside phosphorylase n=1 Tax=Ciona
           intestinalis RepID=UPI0000522022
          Length = 287

 Score =  308 bits (789), Expect = 2e-82,   Method: Composition-based stats.
 Identities = 105/271 (38%), Positives = 155/271 (57%), Gaps = 7/271 (2%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL 71
              D +K+   +  P++  I GSGL  L + +EN + + Y ++P F  STV GH G+LV 
Sbjct: 16  VSADFLKSKMGNVKPKIGIICGSGLSGLGEVVENKIVVKYSEIPSFVESTVPGHKGQLVF 75

Query: 72  GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
           G + G  VVCM+GR H YEG    ++   +R  KL+G E++  TNAAG + PE   G  +
Sbjct: 76  GQISGKDVVCMQGRFHPYEGYPGWVVGFPLRVMKLIGIEMVLATNAAGGINPEFKVGDFM 135

Query: 132 ALKDHINTM---PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEG 186
            +KDHI+       TP+VG ND  FG RF  + +AYD   R L ++ A + G+   + +G
Sbjct: 136 LIKDHISFTGLAGYTPLVGPNDSSFGPRFPPMNDAYDKNLRTLFKQCASDLGYDDFMRDG 195

Query: 187 VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA--EGL 244
           V+ +  GP++ET AE+R++  +GGD  GMS V EV++ARHC +KV+A S ITN    E  
Sbjct: 196 VYCNVFGPSYETIAELRLLLKLGGDAAGMSTVQEVVTARHCGIKVIACSLITNECILEYD 255

Query: 245 SDVKLSHAQTLAAAELSKQNFINLICGFLRK 275
           +D  + H + L  A         L+  F+ K
Sbjct: 256 TDKTVCHDEVLQTANDRAHQMQTLVAKFIGK 286


>UniRef50_C1TMH4 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002
           RepID=C1TMH4_9BACT
          Length = 272

 Score =  307 bits (786), Expect = 4e-82,   Method: Composition-based stats.
 Identities = 110/266 (41%), Positives = 155/266 (58%), Gaps = 1/266 (0%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
              +  IK     FTP +A +LGSGLGALAD IEN + I YE++P +P+ST  GHAG LV
Sbjct: 6   DEALRTIKDRVG-FTPDIAVVLGSGLGALADAIENPIVIPYEEIPHWPMSTAPGHAGRLV 64

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
            G   G  VV M+GR HFYEG  M  +   +R F   G      +NA+G +   +  G +
Sbjct: 65  AGSFCGKSVVAMQGRLHFYEGYQMDQVVFPVRVFGRWGIPYFVASNASGGIGYGLVPGDM 124

Query: 131 VALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVS 190
           V + DHIN M   P++G N    GERF  ++ AYD +   + ++V++++G     GV+V+
Sbjct: 125 VLIHDHINLMGTNPLIGPNLSELGERFPDMSYAYDRDLLDIAEEVSRDKGITTRRGVYVA 184

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
           + GP++ET AEIRM + +G DVVGMS VPEVI AR   +KV AVS + N A G++   LS
Sbjct: 185 FTGPSYETPAEIRMARTLGADVVGMSTVPEVIVARQAGMKVFAVSCVANYAAGMTASALS 244

Query: 251 HAQTLAAAELSKQNFINLICGFLRKI 276
             + L     +      L+ G + K+
Sbjct: 245 EQEVLDEMGKAAGKLTALVGGVIEKL 270


>UniRef50_C3J8Q8 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=2 Tax=Bacteria RepID=C3J8Q8_9PORP
          Length = 274

 Score =  305 bits (781), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 103/271 (38%), Positives = 149/271 (54%), Gaps = 3/271 (1%)

Query: 8   HNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAG 67
                  D +    P F  ++  ILGSGLG L ++IE+   I Y ++P F  ST  GH G
Sbjct: 4   KMYHEAADFLLKRLP-FKAKIGIILGSGLGELGNKIEDPTIIPYSEIPNFAHSTAIGHKG 62

Query: 68  ELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGA 127
             + G L GVPVV M+GR H+YEG  M  +T  +R  KL+G E LF +NAAG +      
Sbjct: 63  NFICGKLGGVPVVAMQGRFHYYEGYPMERVTFPVRVMKLIGVETLFVSNAAGGINNTYHV 122

Query: 128 GSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGV 187
           G L+ ++DHIN +P  P++G N   FG RF  +  AYD +  A  +++AKEE   + +GV
Sbjct: 123 GDLMIIRDHINNLP-NPLIGPNMGEFGVRFPDMTRAYDRDLIARAERIAKEENIEVRKGV 181

Query: 188 FVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDV 247
           +V   GP++ET AE    Q +GGD +GMS VPEV+ ARH  ++V  +S ITN        
Sbjct: 182 YVGLTGPSYETPAEYLFYQRVGGDAIGMSTVPEVLVARHAGIRVFGMSVITNEGWHFEGD 241

Query: 248 KLS-HAQTLAAAELSKQNFINLICGFLRKIA 277
             +   + + AA  + +    +    + +IA
Sbjct: 242 YTNDAQEVIDAANAASERMGRIFQRLISEIA 272


>UniRef50_Q7KV94 CG16758, isoform B n=33 Tax=cellular organisms RepID=Q7KV94_DROME
          Length = 353

 Score =  305 bits (781), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 112/275 (40%), Positives = 159/275 (57%), Gaps = 10/275 (3%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
               D I T      P++  I GSGLG+LAD I++     YEK+P FPVSTV GHAG LV
Sbjct: 75  EEIADFI-TKGSGMRPKIGIICGSGLGSLADMIQDPKIFEYEKIPNFPVSTVEGHAGRLV 133

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
           +G L+G  V+ M+GR HFYEG  +   +  +R  KL G E LF TNAAG + P    G +
Sbjct: 134 VGTLEGATVMAMQGRFHFYEGYPLAKCSMPVRVMKLCGVEYLFATNAAGGINPRFAVGDI 193

Query: 131 VALKDHIN---TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTE 185
           + + DH+N       +P+ G ND RFG RF +L N+Y+ +      ++AK  G    +  
Sbjct: 194 MLMHDHVNMLGFAGNSPLQGPNDPRFGPRFPALVNSYNKDLINKAIEIAKAMGIESNIHV 253

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAE--- 242
           GV+    GPN+ET AE++ ++++G D VGMS V EVI+ARHCD+KV A S ITN      
Sbjct: 254 GVYSCLGGPNYETIAELKALRMMGVDAVGMSTVHEVITARHCDMKVFAFSLITNKCATEY 313

Query: 243 -GLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
               D + +H + +A A+  ++    L+   +R+I
Sbjct: 314 SDKKDDEANHDEVMAVAKNRQKACCELVSRLIREI 348


>UniRef50_C7LVA5 Inosine guanosine and xanthosine phosphorylase family n=2
           Tax=Desulfovibrionales RepID=C7LVA5_DESBD
          Length = 278

 Score =  304 bits (780), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 101/272 (37%), Positives = 136/272 (50%), Gaps = 1/272 (0%)

Query: 5   QFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHG 64
                 L   + IK   P   P+   +LGSGLG          +I Y  +PGFPVSTV G
Sbjct: 3   DIQTRALTATEWIKNNCPSA-PKTGLVLGSGLGKWIKPAWIQKSIPYSDIPGFPVSTVEG 61

Query: 65  HAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPE 124
           HAG L++  ++G PV    GR H YEG     +T  I    LLG   L  TNAAG+L P 
Sbjct: 62  HAGALLVAEIKGTPVFIFSGRFHLYEGYRPQEVTLPIVCLALLGAGNLILTNAAGALNPL 121

Query: 125 VGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT 184
              G L+ L DHIN     P+ G N D +G RF  ++  Y    R    +     G  L 
Sbjct: 122 FATGGLMLLTDHINMTGHNPLTGPNVDAWGPRFPDMSQVYCPTLREQAMQAGLACGQRLE 181

Query: 185 EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL 244
           +GV+V+  GP+ ET AE RM +I+G D +GMS  PE I+A H  LKV+ +S +TN     
Sbjct: 182 QGVYVAVAGPSLETPAETRMYRIMGADAIGMSTAPEAITAHHMGLKVLGISCLTNKNLPD 241

Query: 245 SDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
              + SHA+ L+ A  S     +L+   +  +
Sbjct: 242 CMAETSHAEILSQANASADALGSLLSALIPNL 273


>UniRef50_A7HJP7 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Fervidobacterium nodosum Rt17-B1
           RepID=A7HJP7_FERNB
          Length = 267

 Score =  303 bits (777), Expect = 3e-81,   Method: Composition-based stats.
 Identities = 101/271 (37%), Positives = 150/271 (55%), Gaps = 5/271 (1%)

Query: 6   FSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH 65
                    + I++ K    P++A ILGSGLG L +++E    ++Y+ +P FP ST  GH
Sbjct: 1   MDKRVKEACEFIES-KIKTKPKIALILGSGLGFLTEKVEFKQELNYKDIPNFPYSTAPGH 59

Query: 66  AGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
            G+LV G L G  VV + GR H YEG   + +   I T K+LG E +  TNAAG++    
Sbjct: 60  EGKLVFGELFGKEVVVLSGRFHIYEGWNPSDIKIVIHTLKMLGIEKILITNAAGAVNTTY 119

Query: 126 GAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE 185
             G +V +KD IN     P+ G ND+  G RF  +   +D ++   L+++  E      E
Sbjct: 120 KPGDIVLVKDVINFTFRNPLRGPNDNDLGPRFPDMLGVFDKDWMGKLKQIYPEM----KE 175

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           GV++S  GP +ET AEIR ++ +G D+VGMS VPE+I   H  +K + +S  TNMA G+ 
Sbjct: 176 GVYISLTGPTYETPAEIRAVRKMGADLVGMSTVPELIVCAHVGIKALVLSCATNMAAGIL 235

Query: 246 DVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           D  LSH + +  A L K+ F  ++   L  +
Sbjct: 236 DQPLSHEEVVEVANLVKEKFTEIVKKALEVL 266


>UniRef50_B6YR86 Purine-nucleoside phosphorylase n=1 Tax=Candidatus Azobacteroides
           pseudotrichonymphae genomovar. CFP2 RepID=B6YR86_AZOPC
          Length = 270

 Score =  303 bits (776), Expect = 5e-81,   Method: Composition-based stats.
 Identities = 98/265 (36%), Positives = 145/265 (54%), Gaps = 1/265 (0%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL 71
             +  ++      T ++  ILG+GLG LA+ I N   I YEK+P FP+STV GH G+L++
Sbjct: 7   ETVSWLRPKVSAET-KIGIILGTGLGELANSITNKTEIPYEKIPHFPISTVEGHNGKLLI 65

Query: 72  GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
           G L    V  M+GR H+YEG  M+ +T  +R  + L    L  +NAAG +      G ++
Sbjct: 66  GQLGEKSVAVMQGRFHYYEGYDMSHITYPVRVMQFLEFNYLIISNAAGGINATFQIGDIM 125

Query: 132 ALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSY 191
            ++DHIN  P  P+ G N   FG RF  ++  YD E R+L   V K+    L  G +V  
Sbjct: 126 LIEDHINLFPKNPLRGRNFPEFGVRFPDMSQVYDKELRSLAISVTKKNNIKLQFGTYVGV 185

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH 251
            GP FET AE    +IIGGD +GMS +PEVI ARH  L+V+A S IT++      ++++H
Sbjct: 186 QGPTFETPAEYNYFRIIGGDAIGMSTIPEVIVARHGGLRVLAFSIITDLGILGKIIEVNH 245

Query: 252 AQTLAAAELSKQNFINLICGFLRKI 276
                A   ++     +I   ++ +
Sbjct: 246 KDVRKAGNSAQPQMAFIIKEIIKYL 270


>UniRef50_A7S700 Predicted protein n=3 Tax=cellular organisms RepID=A7S700_NEMVE
          Length = 295

 Score =  303 bits (776), Expect = 5e-81,   Method: Composition-based stats.
 Identities = 106/278 (38%), Positives = 146/278 (52%), Gaps = 9/278 (3%)

Query: 7   SHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHA 66
                     I+  +  + P +  I GSGL +L D +     I YEK+P FP STV GH 
Sbjct: 18  YDEVDAICQNIR-NQTSYQPTIGVICGSGLSSLGDLVTEKTVIPYEKIPQFPRSTVPGHQ 76

Query: 67  GELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVG 126
           G+LV G L G  VV M+GR H YEG     +T  +R    LG + L  TNAAG LR +  
Sbjct: 77  GQLVFGRLNGTTVVMMQGRTHLYEGYDPGQITLPVRVMVHLGIKHLVVTNAAGGLRQDWN 136

Query: 127 AGSLVALKDHIN---TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP- 182
            G ++ +KDHIN       +P+ G ND RFG RF +L++AY+ + + L  + A E GF  
Sbjct: 137 VGDIMVIKDHINLAGLTGLSPLRGCNDSRFGLRFPALSDAYNKDLQKLALETASELGFAD 196

Query: 183 -LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA 241
               GV+ +  GP FET AE R +Q  G D VGMS V EV  ARH  + V+ +S ITN+A
Sbjct: 197 FTRTGVYCAQVGPCFETPAECRFLQNAGVDAVGMSTVHEVSVARHAGVTVLGISLITNIA 256

Query: 242 E---GLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
               G ++   +H + L        +   L+   L+K+
Sbjct: 257 VLGYGDNEQPANHDEVLETGRRRASDMQKLVSTILQKL 294


>UniRef50_A4CJ72 Purine nucleoside phosphorylase n=15 Tax=Bacteroidetes
           RepID=A4CJ72_9FLAO
          Length = 271

 Score =  302 bits (775), Expect = 6e-81,   Method: Composition-based stats.
 Identities = 96/272 (35%), Positives = 148/272 (54%), Gaps = 1/272 (0%)

Query: 5   QFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHG 64
                    +  +K       P +  +LGSGLG +AD++E++    Y  +P FP++TV  
Sbjct: 1   MTEKQLDKSVAYLKDR-GFDNPEIGIVLGSGLGRMADELEDSRVAHYHNIPNFPLATVEF 59

Query: 65  HAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPE 124
           H+G+L  G + G  VV M+GR H YEG     +T  IR  + LG   L  +NAAG++  +
Sbjct: 60  HSGKLFCGTIHGKKVVVMQGRFHLYEGYDFFDITYPIRVMERLGIRKLLISNAAGAVNLD 119

Query: 125 VGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT 184
              G L+ + DHIN   G+P+   N   FGERF  ++  YD E +  ++++AK     L 
Sbjct: 120 FQKGDLMLITDHINLQGGSPLAFKNVADFGERFVDMSCPYDREMQGRIREIAKGTDCVLR 179

Query: 185 EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL 244
           EGV+ +  GP  ET AE RM+  +G D VGMS VPEVI A H  L V A+S IT++ +  
Sbjct: 180 EGVYAAVFGPQLETRAEYRMLGRLGADAVGMSTVPEVIVANHLKLPVAAISVITDLGDPD 239

Query: 245 SDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           +   ++  + LA A  ++   + ++   +R+I
Sbjct: 240 NLEPVNVTEILAVAARAEPGLVRIMKELIREI 271


>UniRef50_D1B5G3 Inosine guanosine and xanthosine phosphorylase family n=2
           Tax=Synergistaceae RepID=D1B5G3_THEAS
          Length = 276

 Score =  302 bits (774), Expect = 7e-81,   Method: Composition-based stats.
 Identities = 101/267 (37%), Positives = 155/267 (58%), Gaps = 1/267 (0%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
           +  +  I+   P  TP +  +LGSG+G     ++N V++ YE++P +P ST  GHAG L 
Sbjct: 8   VEALGAIRKLVP-VTPDLVMVLGSGVGDFVRVLDNPVSVPYEEIPWWPRSTAPGHAGVLH 66

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
           +G L  + V  ++GR H+YEG  M  +   +R     G ++   TNA+G +      G  
Sbjct: 67  VGRLGTINVAVLQGRVHYYEGYSMEEVVFPVRVMGEWGAKVFVATNASGGIDRSYSPGQW 126

Query: 131 VALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVS 190
           V ++DHIN M   P+VG N+D +G RF  +  AYD +   L+++ A   G  L  GV+V+
Sbjct: 127 VLIEDHINLMGANPLVGPNEDFWGVRFPDMTEAYDRDLMRLMERAASRIGVALGRGVYVA 186

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
             GP+FET AEIRM+  +GG +VGMS VPEVI+ARH  L+V+A+S + N A G+S   L+
Sbjct: 187 MSGPSFETPAEIRMLSKLGGTLVGMSTVPEVIAARHMGLRVLALSCVANYAAGISPNPLT 246

Query: 251 HAQTLAAAELSKQNFINLICGFLRKIA 277
           H + L     +  +   L+  FL +++
Sbjct: 247 HEEVLREVSRATGDLCRLLPAFLEEMS 273


>UniRef50_C4QLI3 Purine nucleoside phosphorylase n=2 Tax=Schistosoma mansoni
           RepID=C4QLI3_SCHMA
          Length = 414

 Score =  302 bits (773), Expect = 1e-80,   Method: Composition-based stats.
 Identities = 106/265 (40%), Positives = 149/265 (56%), Gaps = 7/265 (2%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
                  P +  I GSGLG LAD +++ + I Y K+P FP ++V GH+G L+ G L G  
Sbjct: 147 QKLTSIVPEIGIICGSGLGKLADGVKDKITIPYTKIPNFPQTSVVGHSGNLIFGTLSGRK 206

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           VV M+GR H YEG     +   IR  KLLG ++L  +NAAG L   +  G  V LKDHI 
Sbjct: 207 VVVMQGRFHMYEGYSNDTVALPIRVMKLLGVKILMVSNAAGGLNRSLKLGDFVILKDHIY 266

Query: 139 TMP---GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPG 193
                    +VG N + FG RF +L+NAYD + R L  +VA+E GF   + +GV+V   G
Sbjct: 267 LPGLGLNNILVGPNQEEFGTRFPALSNAYDRDLRKLAVQVAEENGFGNLVHQGVYVMNGG 326

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKL--SH 251
           P +ET AE  M+  +G DVVGMS +PEV+ ARHC ++V AVS +TN++    +  L  +H
Sbjct: 327 PCYETPAECTMLLNMGCDVVGMSTIPEVVIARHCGIQVFAVSLVTNISVLDVESDLKPNH 386

Query: 252 AQTLAAAELSKQNFINLICGFLRKI 276
            + LA      +   +     + K+
Sbjct: 387 EEVLATGAQRAELMQSWFEKIIEKL 411



 Score =  139 bits (351), Expect = 9e-32,   Method: Composition-based stats.
 Identities = 50/126 (39%), Positives = 67/126 (53%), Gaps = 6/126 (4%)

Query: 14  IDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH 73
            D I      F P +  I GSGLG LAD +++ + I Y K+P FP ++V GH+G L+ G 
Sbjct: 8   ADHIFKSV-RFKPEIGIICGSGLGKLADGVKDKITIPYTKIPNFPQTSVVGHSGNLIFGT 66

Query: 74  LQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVAL 133
           L G  VV M+GR H YEG     +   IR  KLLG ++L  +NAAG L   +        
Sbjct: 67  LSGRKVVVMQGRFHMYEGYSNDTVALPIRVMKLLGVKILMVSNAAGGLNRSLK-----LD 121

Query: 134 KDHINT 139
            D+ N 
Sbjct: 122 ADYFNR 127


>UniRef50_Q5YBA4 Purine nucleoside phosphorylase n=2 Tax=Singapore grouper
           iridovirus RepID=Q5YBA4_9VIRU
          Length = 285

 Score =  301 bits (771), Expect = 2e-80,   Method: Composition-based stats.
 Identities = 99/277 (35%), Positives = 143/277 (51%), Gaps = 8/277 (2%)

Query: 7   SHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHA 66
                     +        P +  + GSGLG + D +E ++ ++Y  +P FPV +V GHA
Sbjct: 4   YDLAKETAAWLNKQL-QIRPVLGIVCGSGLGKIGDSLETSITVAYSDIPNFPVGSVKGHA 62

Query: 67  GELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVG 126
           G L+ G + GV  VCMKGR H YEG      T  +R FK LG +++  TNAAG L P   
Sbjct: 63  GSLIFGSVNGVSCVCMKGRFHLYEGHTAARATFPMRVFKALGVKIVVLTNAAGGLNPSYR 122

Query: 127 AGSLVALKDHIN---TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL 183
            G  + ++DHIN        P+ G NDD  GERF S+ + YD   R      A+E G   
Sbjct: 123 PGDFMVVRDHINLPGLAGANPLTGPNDDTEGERFPSMTSVYDKTLRKYAISAARELGMSY 182

Query: 184 --TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA 241
              EGV+    GP+FET AE ++++++G D VGMS  PE I A+H  ++ +AVS I+N+ 
Sbjct: 183 ATHEGVYCCVNGPSFETPAECKILRLMGSDAVGMSTAPETIVAKHGGMRCLAVSLISNVI 242

Query: 242 EGLSDVKL--SHAQTLAAAELSKQNFINLICGFLRKI 276
               +     +H + L A E +      L+   + KI
Sbjct: 243 ASNCETPAEPTHEEVLRAGEEASARMTALVKLVIEKI 279


>UniRef50_B0VG85 Purine nucleoside phosphorylase 1 (Purine nucleoside phosphorylase
           I) (PNP I) (PU-NPase I) (Inosine phosphorylase) n=1
           Tax=Candidatus Cloacamonas acidaminovorans
           RepID=B0VG85_9BACT
          Length = 277

 Score =  299 bits (767), Expect = 5e-80,   Method: Composition-based stats.
 Identities = 104/265 (39%), Positives = 153/265 (57%), Gaps = 1/265 (0%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
               +KT  P   P++A ILG+GL  +A+      +I Y ++PGF  ST   H G L+L 
Sbjct: 7   TSAWLKTKLPK-QPQIAVILGTGLSNMAEVFPLLYSIPYNQIPGFVQSTAPTHKGNLLLC 65

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            ++G+PV+ ++GR H+YEG  M  +   +R    LG ++L  TNA+GSLR E+  G++V 
Sbjct: 66  EVEGIPVIFLQGRFHYYEGYSMQEVVFPVRVLSALGIKVLIVTNASGSLRKELEPGTIVQ 125

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           L+DHIN M   P++G+NDD  GERF S+   YD E   L  KVA + G    +GV+++  
Sbjct: 126 LQDHINFMGTNPLIGMNDDDLGERFPSMNKVYDPELCLLADKVAFDLGIKTAKGVYIAVT 185

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP+ ET AE       G D+VGMS VPEVI+ARH  LKV+A S +TN +    ++  S  
Sbjct: 186 GPSLETKAECSAFASWGADLVGMSTVPEVITARHSGLKVLAYSIVTNYSNLFHNLAHSQE 245

Query: 253 QTLAAAELSKQNFINLICGFLRKIA 277
           +    A +S +    LI   + ++ 
Sbjct: 246 EIQRIANISGKQLQKLIAELILRLT 270


>UniRef50_A7VBG8 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A7VBG8_9CLOT
          Length = 306

 Score =  299 bits (767), Expect = 5e-80,   Method: Composition-based stats.
 Identities = 99/267 (37%), Positives = 148/267 (55%), Gaps = 3/267 (1%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
              +  I T K    P +  +LGSGLG  A  +++ V + Y+++PGFPVSTV GH G  +
Sbjct: 39  DEAVRYI-TDKIKMKPEIGIVLGSGLGD-AFTMDDPVYVYYKEIPGFPVSTVAGHKGRFI 96

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
            G+  G P+V M+GR H+YEG  M  +   IR   LLG   L  TNAAG +  E+  G +
Sbjct: 97  FGYSCGKPIVVMQGRVHYYEGYSMQDVVKPIRLMGLLGIRWLILTNAAGGISEELAPGDI 156

Query: 131 VALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVS 190
           + + D I++   +P++G N D FG RF  +++ YD E   + +KV ++ G  + EG ++ 
Sbjct: 157 MIISDQISSFVPSPLIGRNIDEFGVRFPDMSHIYDKEKIQISRKVFEQIGLHVVEGTYIQ 216

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
             GP +ET AEIRM Q++G D VGMS   E I+A H  ++V   SAI+N A GL   +L 
Sbjct: 217 ATGPQYETPAEIRMFQLLGADAVGMSTACEAIAACHMGIRVSGFSAISNKAAGLG-AELK 275

Query: 251 HAQTLAAAELSKQNFINLICGFLRKIA 277
           H   L  ++        L+   +   +
Sbjct: 276 HEDILDRSKEMSDKMSRLLTELIESYS 302


>UniRef50_A8PXS8 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           family protein n=4 Tax=root RepID=A8PXS8_BRUMA
          Length = 295

 Score =  299 bits (766), Expect = 7e-80,   Method: Composition-based stats.
 Identities = 102/282 (36%), Positives = 154/282 (54%), Gaps = 6/282 (2%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           ++   +         I+K  +    P++  I GSGLG++AD IE A  +SY K+PGFP+S
Sbjct: 14  INPKSYDDLSEIAKSILKQIQLKEVPKIGIICGSGLGSIADFIEQAEILSYTKIPGFPIS 73

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYE-GRGMTIMTDAIRTFKLLGCELLFCTNAAG 119
            V GH   LV G++    V+CM+GR H YE G  + +    +R   LLG E L  +NAAG
Sbjct: 74  HVIGHKSNLVFGYINEKYVICMQGRFHPYEYGMDLALCAMPVRILHLLGVETLIVSNAAG 133

Query: 120 SLRPEVGAGSLVALKDHINT---MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVA 176
            L      G L+ +KDHI        +P VGL+D RFGERF SL  AYD + R L   VA
Sbjct: 134 GLNSNFKVGDLMIIKDHIFFPGLAGFSPFVGLHDQRFGERFVSLHEAYDPKLRKLAIDVA 193

Query: 177 KEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSA 236
           + +   + EGV+    GP FE+ AE+RM++++G D +GMS   EV+ A    ++V   S 
Sbjct: 194 RRQKIRIHEGVYAMNGGPQFESPAELRMLKMLGTDAIGMSTCHEVVVACQMGMRVFGCSL 253

Query: 237 ITNMAEGLSDVK--LSHAQTLAAAELSKQNFINLICGFLRKI 276
           ITN+A    +    ++H + L   E +++   + +   ++ +
Sbjct: 254 ITNIANLDHENAVMVTHEEVLKTGEEAQERTCSFVSEIVKNL 295


>UniRef50_Q9BMI9 Purine-nucleoside phosphorylase n=1 Tax=Schistosoma mansoni
           RepID=Q9BMI9_SCHMA
          Length = 287

 Score =  299 bits (766), Expect = 8e-80,   Method: Composition-based stats.
 Identities = 106/265 (40%), Positives = 149/265 (56%), Gaps = 7/265 (2%)

Query: 19  TYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVP 78
                  P +  I GSGLG LAD +++ + I Y K+P FP ++V GH+G L+ G L G  
Sbjct: 20  QKLTSIVPEIGIICGSGLGKLADGVKDKITIPYTKIPNFPQTSVVGHSGNLIFGTLSGRK 79

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           VV M+GR H YEG     +   IR  KLLG ++L  +NAAG L   +  G  V LKDHI 
Sbjct: 80  VVVMQGRFHMYEGYSNDTVALPIRVMKLLGVKILMVSNAAGGLNRSLKLGDFVILKDHIY 139

Query: 139 TMP---GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPG 193
                    +VG N + FG RF +L+NAYD + R L  +VA+E GF   + +GV+V   G
Sbjct: 140 LPGLGLNNILVGPNQEAFGTRFPALSNAYDRDLRKLAVQVAEENGFGNLVHQGVYVMNGG 199

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKL--SH 251
           P +ET AE  M+  +G DVVGMS +PEV+ ARHC ++V AVS +TN++    +  L  +H
Sbjct: 200 PCYETPAECTMLLNMGCDVVGMSTIPEVVIARHCGIQVFAVSLVTNISVLDVESDLKPNH 259

Query: 252 AQTLAAAELSKQNFINLICGFLRKI 276
            + LA      +   +     + K+
Sbjct: 260 EEVLATGAQRAELMQSWFEKIIEKL 284


>UniRef50_D1Y3S3 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y3S3_9BACT
          Length = 279

 Score =  296 bits (757), Expect = 8e-79,   Method: Composition-based stats.
 Identities = 106/276 (38%), Positives = 149/276 (53%), Gaps = 1/276 (0%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           M   +++      ++ I+       PR A ILGSGLG LA+ +E+ V I Y ++P +  S
Sbjct: 1   MDMKEYARQVTEALEAIEARVSGV-PRAALILGSGLGMLAEAVEDPVVIPYAEIPHWKTS 59

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           T  GHAG LV G L GVPVV M+GR H YEG      T  IR F   G + L  TNA+G 
Sbjct: 60  TAPGHAGRLVCGTLSGVPVVVMQGRLHCYEGYTPQETTFPIRVFGQWGVKTLLVTNASGG 119

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           +  E   G +  + DHIN     P+ G N+  +G RF  ++  Y     ALL++ A+  G
Sbjct: 120 INYEYANGDVALITDHINLTGMNPLRGANNPEWGARFPDMSEPYSRRLVALLEESAQSLG 179

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
                GV++   GP++ET AEIRM + +G D+VGMS V EVI A H  ++V  VS + N+
Sbjct: 180 LLTRRGVYIGLAGPSYETPAEIRMARAMGADLVGMSTVHEVIVANHMGMEVCGVSCVANL 239

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           A G+  VKLS  + L+    +      L+  FL  +
Sbjct: 240 AAGMRPVKLSEEEVLSEMGRAAARISALVGKFLELL 275


>UniRef50_D2QX64 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2QX64_9PLAN
          Length = 303

 Score =  295 bits (756), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 105/269 (39%), Positives = 147/269 (54%), Gaps = 1/269 (0%)

Query: 6   FSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH 65
                      IK+     TP    ILG+GLG+L DQIE   AI YE +P FP ST   H
Sbjct: 31  IFEKVQEAAAFIKSQWSS-TPHAGIILGTGLGSLVDQIEVEAAIDYENIPHFPKSTAISH 89

Query: 66  AGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
            G LV G L  +PV+ M+GR H YEG  +  +T  +R  K +G  LL  +NA G + P+ 
Sbjct: 90  RGRLVCGKLGKLPVMAMEGRFHMYEGYPLDQVTLPVRVMKAMGANLLVVSNACGGMNPQY 149

Query: 126 GAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE 185
             G ++ ++DHIN M   P++G+NDDR G RF  + + Y+        ++A++E      
Sbjct: 150 RTGDIMLIEDHINLMGANPLIGINDDRLGPRFPDMCHPYEPALIDRALEIARKENIVAHR 209

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           GVFV+  GPN ET AE R +++IG DVVGMS VPEVI A H +++VV  S IT+M    +
Sbjct: 210 GVFVAVSGPNLETRAEYRFLRLIGADVVGMSTVPEVIVAVHSNMRVVGFSIITDMCLPDA 269

Query: 246 DVKLSHAQTLAAAELSKQNFINLICGFLR 274
                  + +A A  ++     L+ G L 
Sbjct: 270 LEPADVQKIIAVANTAQPKLCKLVQGVLA 298


>UniRef50_C8V0B3 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           (AFU_orthologue; AFUA_6G05320) n=17 Tax=Leotiomyceta
           RepID=C8V0B3_EMENI
          Length = 315

 Score =  295 bits (755), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 114/300 (38%), Positives = 159/300 (53%), Gaps = 35/300 (11%)

Query: 12  FCIDIIKTYKPD--FTPRVAFILGSGLGALADQIEN--AVAISYEKLPGFPVSTVHGHAG 67
              D IK   P+    PRVA + GSGLG LA+ I+N   V I Y  +P FP  TV GHAG
Sbjct: 15  EAFDFIKKLLPEPLKAPRVAIVCGSGLGGLANTIDNDLRVEIDYSDIPHFPHLTVAGHAG 74

Query: 68  ELVLGHLQG-VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVG 126
           +LV G +   VPVV M GR H+YEG  +  +T  IR FKLLG + +  TNAAG L P+  
Sbjct: 75  KLVFGLIDKKVPVVLMVGRAHYYEGHSIDQVTFPIRVFKLLGIDTVVLTNAAGGLNPDYA 134

Query: 127 AGSLVALKDHI---NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE----- 178
            G +V L DHI         P+ G N + FG RF  L++AYD + R  + +  ++     
Sbjct: 135 VGDIVLLNDHIFLAGLAGIHPLRGPNCEEFGPRFPPLSDAYDLDLRRQVHEAWRKYLDPC 194

Query: 179 EGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
               L EGV+    GP++ET AE R+++ +G D+VGMS VPE++ ARHC L+++A S +T
Sbjct: 195 SKRRLHEGVYAFVCGPSYETRAECRLLRQLGADLVGMSTVPEIVVARHCGLRIIAFSLVT 254

Query: 239 N----------------------MAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           N                      +   L + K +H + L A   + Q+   L+   + KI
Sbjct: 255 NNAVLSPVPRGDDHLIQGRDVKELDAILQEGKANHEEVLEAGREAAQDMQKLVVHVISKI 314


>UniRef50_D0MFN5 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Rhodothermus marinus DSM 4252 RepID=D0MFN5_RHOM4
          Length = 279

 Score =  295 bits (755), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 107/263 (40%), Positives = 145/263 (55%), Gaps = 3/263 (1%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +D ++       P VA ILGSGLGALA+ +  AV +   ++PG+P  TV GHAG LV G
Sbjct: 10  ALDWLRPKL-REAPEVALILGSGLGALAEAVSEAVEVPVREIPGYPAPTVSGHAGRLVFG 68

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L+G  VV ++GR H YEG     +T  +R    LG + L  TNAAG L P    G+L+ 
Sbjct: 69  RLEGCRVVVLQGRLHCYEGYPPQTVTLPVRLVHALGAQRLIVTNAAGGLNPHFRPGTLMF 128

Query: 133 LKDHINTMPGTPMVG--LNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVS 190
           + DHIN     P+VG   +          ++ AYD ++ A  + VA   G P   GV++ 
Sbjct: 129 IVDHINAAFRNPLVGQLADRRPLMRGAPDMSRAYDLDWLAEAETVALRLGIPTQRGVYLW 188

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
             GP++ET AEIRM + +G D VGMS VPEV+ AR   +KV+ +S ITNMA GL    L+
Sbjct: 189 TLGPSYETKAEIRMYRRMGADAVGMSTVPEVLQARQLGMKVLGISTITNMAAGLHAGPLT 248

Query: 251 HAQTLAAAELSKQNFINLICGFL 273
           H + L      +     LI G L
Sbjct: 249 HEEVLQVGLQVRDRLERLIRGIL 271


>UniRef50_D2MQ16 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Bulleidia extructa W1219 RepID=D2MQ16_9FIRM
          Length = 273

 Score =  294 bits (753), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 102/266 (38%), Positives = 152/266 (57%), Gaps = 1/266 (0%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
              +D I+T K D  P +  ILGSGLG L  Q+EN + I+Y+++PGF  +T   H GEL+
Sbjct: 9   QEALDFIRT-KTDMVPEIGLILGSGLGTLVTQLENTITIAYQEIPGFLQTTNPSHKGELI 67

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
            G L G  VVCM GR H YEG   + +   +R  KLLG ++L  TNAAG++      G +
Sbjct: 68  FGFLNGKKVVCMSGRFHSYEGFSFSELVIPVRLLKLLGIQILMTTNAAGAVNESYRPGDV 127

Query: 131 VALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVS 190
           + ++DH+     +PM G N++ FG RF+ ++  Y  E R   ++VA++      EG +  
Sbjct: 128 MIIRDHLFFGIESPMRGFNEEDFGSRFYDVSTLYTPELREKAKEVARDFPLTFHEGNYFF 187

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
             GP+FET AEIR ++I+GGD VGMS V E ++A HC LKV++ S  TNMA G+ +  LS
Sbjct: 188 MQGPHFETPAEIRAIRILGGDTVGMSTVTETLTAGHCGLKVLSFSVCTNMAAGILEQPLS 247

Query: 251 HAQTLAAAELSKQNFINLICGFLRKI 276
             +          +    +   + ++
Sbjct: 248 DEEVNEVGRNISSHLAAYMYELVGQL 273


>UniRef50_B7A7P1 Inosine guanosine and xanthosine phosphorylase family n=3
           Tax=Thermaceae RepID=B7A7P1_THEAQ
          Length = 276

 Score =  294 bits (753), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 99/276 (35%), Positives = 152/276 (55%), Gaps = 1/276 (0%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           M+ +         +  I+  K  F P V  +LGSGLG LA+++E    + Y ++P FP+S
Sbjct: 1   MAGMGVYEKIQEAVAAIRQ-KTGFAPEVGIVLGSGLGPLAEEVEKVAEMPYGEIPHFPLS 59

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           T  GHAG LVLG L+G  V+  +GR H+YEG     +   +R    LG      T+AAG 
Sbjct: 60  TAPGHAGRLVLGTLEGKRVLVYQGRVHYYEGYSAEEVVFPVRVGFFLGARTFLLTSAAGG 119

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           L P   AG ++   D++N     P+ G ND+R G RF  +  AYD E   L ++VA+++ 
Sbjct: 120 LNPRFQAGGIMLHLDYLNPSGVNPLRGKNDERLGPRFPVMFGAYDPELVELARRVARKQD 179

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
             L EGV+  + GP+F + AE++M++ +G D +GMS VPEVI+ RH   +V+ +S IT+M
Sbjct: 180 LHLFEGVYAWFLGPSFASRAELKMLRELGADAIGMSTVPEVIALRHLGARVLGLSTITDM 239

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           A    +   +  + L  A  +   F   + G L ++
Sbjct: 240 AVPEREHHATEEEVLEVARRTGPVFRRFVRGILAEL 275


>UniRef50_C3ZRV1 Putative uncharacterized protein (Fragment) n=1 Tax=Branchiostoma
           floridae RepID=C3ZRV1_BRAFL
          Length = 286

 Score =  294 bits (752), Expect = 3e-78,   Method: Composition-based stats.
 Identities = 103/263 (39%), Positives = 148/263 (56%), Gaps = 6/263 (2%)

Query: 20  YKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPV 79
               + P+VA I GSGLG LAD ++    I Y  +P FP STV GH G LV GHL G  V
Sbjct: 14  KTTKYRPKVAVICGSGLGGLADVVQQQDVIDYRDIPNFPQSTVQGHRGRLVFGHLAGKSV 73

Query: 80  VCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN- 138
           +CM+GR H Y+G  +  +   +R FK++G E LF TNAAG L      G ++ +KDHI+ 
Sbjct: 74  ICMQGRFHQYQGYPLWKVAMPVRVFKMIGVETLFVTNAAGGLNRNYNIGDIMIVKDHISM 133

Query: 139 --TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF--PLTEGVFVSYPGP 194
                  P+ G  D+RFG+    +   YD   R L ++VA + G    + EGV V   GP
Sbjct: 134 PGMTTDNPLKGFYDERFGKPSSPVTELYDRGLRELARRVAGDLGLGEAVREGVLVQVGGP 193

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VKLSHAQ 253
           +F+T +   M++ +G D VGMS  PEV  ARHC ++V+ +S +T+MA   SD    +H +
Sbjct: 194 SFDTVSVFNMLRRLGADCVGMSSAPEVTVARHCGIRVLGLSLVTDMAPMESDLPPTNHQE 253

Query: 254 TLAAAELSKQNFINLICGFLRKI 276
            L  A+    +  NL+C  + ++
Sbjct: 254 ILQTAKTRAVDVQNLVCEMISQL 276


>UniRef50_C5EQ75 Purine nucleoside phosphorylase I n=1 Tax=Clostridiales bacterium
           1_7_47FAA RepID=C5EQ75_9FIRM
          Length = 270

 Score =  293 bits (751), Expect = 3e-78,   Method: Composition-based stats.
 Identities = 96/269 (35%), Positives = 149/269 (55%), Gaps = 1/269 (0%)

Query: 8   HNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAG 67
                 +D I++      P +A ILGSGLG  A Q+ENA  I YE +P FP  TV GH+G
Sbjct: 3   SALRETVDYIRSR-TRKVPEIAMILGSGLGDYASQLENADIIPYEDIPNFPKPTVSGHSG 61

Query: 68  ELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGA 127
            L +G + G  +  M+GR H+YEG     +T  +R  ++LG   L  TNA G++      
Sbjct: 62  RLFVGEIAGKCIAVMQGRNHYYEGYDTQTITYPVRVLRMLGAGSLILTNACGAVSRHFVP 121

Query: 128 GSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGV 187
           G L+ +++H+      P+ G + +  G RF  ++  YD EY  L ++ AK+ G  + +GV
Sbjct: 122 GDLMIIENHLAHFCPPPLRGAHLEELGPRFTDMSRPYDPEYMELARRCAKDMGIRIQQGV 181

Query: 188 FVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDV 247
           +  +PGP +ETAAE+R   ++G DVVGMS V E + A +C ++V+ +S ITNM    S  
Sbjct: 182 YGYWPGPTYETAAEVRAYGVLGADVVGMSTVAEDMVAVNCGMRVLGISCITNMTCIHSSG 241

Query: 248 KLSHAQTLAAAELSKQNFINLICGFLRKI 276
           K SH + +   E   +  + L+   + ++
Sbjct: 242 KTSHDEVIQVMEQISEKTVKLLNRIVEEM 270


>UniRef50_A5USV0 Inosine guanosine and xanthosine phosphorylase family n=19
           Tax=Bacteria RepID=A5USV0_ROSS1
          Length = 297

 Score =  292 bits (748), Expect = 7e-78,   Method: Composition-based stats.
 Identities = 114/266 (42%), Positives = 151/266 (56%), Gaps = 4/266 (1%)

Query: 14  IDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH 73
              I   +    PR+A ILGSGLG LAD +  +V I Y ++PGF    V GH GELV+G 
Sbjct: 20  ARSIIAARSPIEPRIALILGSGLGDLADAVTESVTIPYTEIPGFVQPAVVGHRGELVIGL 79

Query: 74  LQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVAL 133
           L G PV  M+GR HFYEG  M  +T  +R    LGC  L  TNAAG L  +   G L+ +
Sbjct: 80  LAGQPVAVMRGRFHFYEGHSMQQVTFPVRVLHALGCTALLATNAAGGLHADWRVGDLMLI 139

Query: 134 KDHI---NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVS 190
            DHI         P+ G NDDR G RF  +  AYD   +A+ + VA E G  L EGV++ 
Sbjct: 140 TDHIFLPGLAGHHPLRGPNDDRLGPRFPPMVGAYDPTLQAVARAVAAELGIALREGVYMM 199

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
             GP FE++AE+RM + +G D VGMS  PEV+ ARH  ++ + +S ITN+A        S
Sbjct: 200 LSGPAFESSAELRMCRALGADAVGMSTAPEVVVARHMGMRCLGLSLITNLALPDGP-PAS 258

Query: 251 HAQTLAAAELSKQNFINLICGFLRKI 276
           H + L A + ++  F  LICG L ++
Sbjct: 259 HQEVLDAGDAARPAFTALICGILARM 284


>UniRef50_A0NS72 Purine nucleoside phosphorylase n=7 Tax=Alphaproteobacteria
           RepID=A0NS72_9RHOB
          Length = 269

 Score =  292 bits (748), Expect = 9e-78,   Method: Composition-based stats.
 Identities = 125/265 (47%), Positives = 172/265 (64%), Gaps = 4/265 (1%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL 71
            C DI++  + + + ++  ILGSGLGALA+++E+AV I Y  L  FPVSTV  H+ ELV 
Sbjct: 7   ECADIVRAAR-EGSYKIGMILGSGLGALAEEVEDAVRIPYSHLTEFPVSTVTSHSSELVA 65

Query: 72  GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
           G L GVPVV + GR H+YEG   T+M   + T K LGCE+L  TNAAGSLR EV  GS +
Sbjct: 66  GTLSGVPVVILSGRAHYYEGGDPTVMRTPVETLKELGCEILLATNAAGSLRQEVAPGSPM 125

Query: 132 ALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSY 191
            + DHIN     P++G  D++   RF  ++ AYDA+ RA ++KVA+E G P+ EGV++ +
Sbjct: 126 LISDHINWSGMNPLIGEEDEK---RFLDMSTAYDADLRAAMKKVAEETGDPVAEGVYMWF 182

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH 251
            GP+FET AEIRM + +G D VGMS VPEVI AR   ++V A+S ITN   G+    LSH
Sbjct: 183 SGPSFETPAEIRMAKTLGADAVGMSTVPEVIMARFLGMRVAAMSIITNYGAGMQTHALSH 242

Query: 252 AQTLAAAELSKQNFINLICGFLRKI 276
            +T + A    +    L+  F+++I
Sbjct: 243 DETKSVALQGMERMKELVRAFVKEI 267


>UniRef50_B9WDS7 Purine nucleoside phosphorylase, putative n=14 Tax=cellular
           organisms RepID=B9WDS7_CANDC
          Length = 307

 Score =  292 bits (747), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 119/295 (40%), Positives = 162/295 (54%), Gaps = 23/295 (7%)

Query: 5   QFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQI--ENAVAISYEKLPGFPVSTV 62
           Q +H      + I  ++    PRV  I GSGLG +AD +  E  + I Y K+PGF VSTV
Sbjct: 13  QLNHASDTIKNKIDQFQELAQPRVMIICGSGLGGIADVLQAEPKLEIPYSKIPGFKVSTV 72

Query: 63  HGHAGELVLGHLQG--VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
            GHAG+LV G +    VPV+CM GR HFYEG      T  +R  KLLG   +  TNAAG 
Sbjct: 73  PGHAGKLVFGLIGKSKVPVMCMVGRLHFYEGYSFQETTFPVRVAKLLGISSVVVTNAAGG 132

Query: 121 LRPEVGAGSLVALKDHINT---MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAK 177
           + P+   G L+ ++DHIN        P+ G N   FG RF  L++AYD E R L    A+
Sbjct: 133 VNPKFKPGDLMVIEDHINFPGLAGYHPLRGPNLSEFGPRFQPLSDAYDYELRKLFITTAR 192

Query: 178 -EEGFP--LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAV 234
            + G    + EG +    GP FE+ AE+RM++ +GGD VGMS VPEVI ARH  L+V+A+
Sbjct: 193 DKLGITRSIYEGTYFFAAGPTFESRAEVRMIKTMGGDAVGMSTVPEVIVARHSGLRVLAL 252

Query: 235 SAITNMAEG-------------LSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           S ITN   G             L +   SHA+ L AA+ + ++   +I   + ++
Sbjct: 253 SLITNAGVGDKPPSAFDENPPALDEGMASHAEVLEAADEASKDVQKIIEEVINQL 307


>UniRef50_Q311R2 Inosine guanosine and xanthosine phosphorylase n=4
           Tax=Desulfovibrio RepID=Q311R2_DESDG
          Length = 276

 Score =  291 bits (744), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 96/265 (36%), Positives = 132/265 (49%), Gaps = 1/265 (0%)

Query: 13  CIDIIKTYKPDFT-PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL 71
             + +K        P+V  +LG+GLG L D +     I Y ++P FP STV  H G  + 
Sbjct: 10  ASEFLKKKLSGHPDPKVGIVLGTGLGGLVDAVSIHTVIDYGEIPDFPRSTVASHQGRFIA 69

Query: 72  GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
           G +   PV+  +GR H YEG     +   +RT    G + L  TNAAG+L P   AG L+
Sbjct: 70  GSIGSTPVLLQQGRCHLYEGYSAGDVCTGVRTMAACGADTLIITNAAGALNPAWSAGDLM 129

Query: 132 ALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSY 191
           A+ DHIN    +P+ G N+D +G RF  ++  YDA+      + A E G  L  GV+   
Sbjct: 130 AITDHINFTGQSPLTGPNNDLWGPRFPDMSAPYDAQLICAAMQKASELGIRLERGVYAGV 189

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH 251
            GP  ET AE RM +  G D VGMS V EVI+ARH  LKV+ VS +TN        +   
Sbjct: 190 RGPQMETPAETRMYKAAGADAVGMSTVLEVIAARHMGLKVLGVSCLTNKNLPDCMQEAPL 249

Query: 252 AQTLAAAELSKQNFINLICGFLRKI 276
            + +  A L+      LI      +
Sbjct: 250 EEVIRVASLAGNRLAKLIAAVTADL 274


>UniRef50_A3ZZ29 Purine nucleoside phosphorylase n=1 Tax=Blastopirellula marina DSM
           3645 RepID=A3ZZ29_9PLAN
          Length = 267

 Score =  290 bits (742), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 97/267 (36%), Positives = 155/267 (58%), Gaps = 2/267 (0%)

Query: 10  PLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGEL 69
                  ++  + +  P+   ILG+GLG+L + I+   +I Y+ LP FP +T   HAG L
Sbjct: 1   MEEIAAAVR-RRWNRRPKAGVILGTGLGSLTEGIDVEASIDYDDLPYFPQTTALSHAGRL 59

Query: 70  VLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGS 129
           + G L GV V+ M+GR H YEG  +  +T  +R  K LG ELL  +NA+G + P   +G 
Sbjct: 60  IGGKLAGVDVLVMEGRFHLYEGYSLDQITLPVRVMKALGAELLVVSNASGGMNPYYESGD 119

Query: 130 LVALKDHINTMPGTPMVGLNDD-RFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVF 188
           ++ ++DHIN M  +P+ G  D+ +  ERF  +++ YD        ++A+ E   + +GV+
Sbjct: 120 IMLIEDHINLMWRSPLQGHADEAKQAERFPDMSSPYDRRLLQRAAEIARREEIRVHQGVY 179

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK 248
           V+  GPN+ET AE R ++ IGGDVVGMS VPEVI AR C L+V+A+S +TN+       +
Sbjct: 180 VAMSGPNYETRAEYRFLRNIGGDVVGMSTVPEVIVARQCGLQVLALSTVTNVCLPDDLGR 239

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRK 275
           +     + AA+ ++     ++   +R+
Sbjct: 240 VGKYDVVNAAKGAEPKLRRIVREVIRE 266


>UniRef50_C3FBK6 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Bacillus thuringiensis serovar monterrey BGSC
           4AJ1 RepID=C3FBK6_BACTU
          Length = 266

 Score =  288 bits (738), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 99/262 (37%), Positives = 152/262 (58%), Gaps = 4/262 (1%)

Query: 15  DIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL 74
           + +K      T + A ++GSGL  + +++E+   I Y ++P F  ST   H GEL+ G+L
Sbjct: 9   EYLKERIISKT-KTAIVIGSGLSGIIEKVEDKNIIPYGEIPEFLHSTAPTHRGELISGYL 67

Query: 75  QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALK 134
            G PVVC+ GR H+YEG  M  + + I+  KLLG E +  TNA+GS+  E+  G LV ++
Sbjct: 68  YGKPVVCLNGRFHYYEGYQMQQVAEYIKVLKLLGIEHIILTNASGSMYQEIVPGDLVVVE 127

Query: 135 DHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGP 194
           DHIN     P+ G ND+ FG RF  ++NAY       ++KV +     L +G +V   GP
Sbjct: 128 DHINFSGLNPLRGKNDESFGPRFVDMSNAYSKRL---IEKVFENSSNGLKKGTYVYGTGP 184

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQT 254
           +FETAAEIR  + +GG +VGMS VPEVI   +C ++V+ +S ++N A G+    +S  + 
Sbjct: 185 SFETAAEIRAFKTLGGTIVGMSTVPEVIMCAYCGIEVLTISCVSNYAPGIPGSNVSDEEL 244

Query: 255 LAAAELSKQNFINLICGFLRKI 276
           +    L++  F  ++     KI
Sbjct: 245 VRVTGLAQDKFSKVLEELFNKI 266


>UniRef50_B9XJR6 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=bacterium Ellin514 RepID=B9XJR6_9BACT
          Length = 274

 Score =  288 bits (737), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 108/269 (40%), Positives = 140/269 (52%), Gaps = 2/269 (0%)

Query: 9   NPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGE 68
           NPL     +        P +A +LGSG      ++   + ISYEKL GFP   V GHAG+
Sbjct: 6   NPLITAQQLG-RLSQLRPTLAIVLGSGFQQAIAEMRIELEISYEKLKGFPPVGVSGHAGK 64

Query: 69  LVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAG 128
           L+LG+L   PV+ + GR H+YEG  M  +T A R     G   L  TNAAG +  +  AG
Sbjct: 65  LILGYLGKTPVLVLSGRAHYYEGHEMEQVTYATRVLAEFGIRDLLLTNAAGGVNRKFKAG 124

Query: 129 SLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVF 188
             + L DHIN M   P+ G    +   RF  +   YD +   LL K  K  G  L +GV+
Sbjct: 125 DFMVLTDHINFMGINPLRGPTIAKL-PRFVDMTCTYDQQLSQLLHKAGKLCGLKLQKGVY 183

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK 248
           ++  GP++ET AEIR    +G D VGMS VPE I AR C + V  VS ITN+A G     
Sbjct: 184 LAVSGPSYETPAEIRAFATLGADAVGMSTVPEAIVARQCGINVAGVSCITNLAAGCGGDT 243

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKIA 277
           LSHA+ L  AE  K     L+  F +  A
Sbjct: 244 LSHAEVLETAERVKNMAARLLNSFAKLYA 272


>UniRef50_C7MNU9 Inosine guanosine and xanthosine phosphorylase family protein n=2
           Tax=Coriobacteriaceae RepID=C7MNU9_CRYCD
          Length = 284

 Score =  287 bits (736), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 105/278 (37%), Positives = 144/278 (51%), Gaps = 6/278 (2%)

Query: 6   FSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH 65
                   +  ++      +P++  +LGSGL  LAD+I +AV I + ++P     T  GH
Sbjct: 7   LDEQLAEAMLFLRQRLHGRSPQIGLVLGSGLNPLADKIADAVHIDFTEVPHMKTVTAAGH 66

Query: 66  AGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
            G  V G L G  V+ M+GR H YEG     +   I     LG E +  TNAAG+L    
Sbjct: 67  VGRFVCGELGGQTVLAMQGRLHAYEGYTAQDVAFPIWLMHRLGIETVITTNAAGALNKSF 126

Query: 126 GAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE 185
             G   A+ DHIN     P+VG++     ER FS+  AYDA  RA    VA E+   L E
Sbjct: 127 APGDFCAISDHINFTGRNPIVGIDPSELAERCFSMTAAYDATLRATAHTVASEKSITLHE 186

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           GV++   GP+FET AEIRM +  G D V MSVV EVI+ARH  ++V+ +S ITN A GL 
Sbjct: 187 GVYLGVLGPSFETPAEIRMFRSWGADTVAMSVVEEVIAARHVGMRVLGLSLITNCAAGLG 246

Query: 246 DVKL------SHAQTLAAAELSKQNFINLICGFLRKIA 277
           +         +    LA A   + +F  L+ G L K++
Sbjct: 247 ETDTCDANAANGEAVLATASAYQDDFAALVIGILEKLS 284


>UniRef50_C1AAZ0 Purine nucleoside phosphorylase n=1 Tax=Gemmatimonas aurantiaca
           T-27 RepID=C1AAZ0_GEMAT
          Length = 277

 Score =  287 bits (734), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 110/274 (40%), Positives = 157/274 (57%), Gaps = 3/274 (1%)

Query: 5   QFSHNPLFCIDIIKTYKPDFTPR--VAFILGSGLGALADQIENAVAISYEKLPGFPVSTV 62
             +       D I+       P      +LGSGLG LAD++ +AV I +  +PGFP +TV
Sbjct: 1   MGAGAARVAADYIRQRVGPAAPAPVCGIVLGSGLGGLADRLVDAVRIPFSHVPGFPTATV 60

Query: 63  HGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLR 122
            GHAG+L++G L   PVV + GR H YEG    +    +R    LG  +   +NAAG +R
Sbjct: 61  AGHAGQLLVGTLADRPVVALAGRFHMYEGHEAALAAFPVRVLHALGAPVYIASNAAGGVR 120

Query: 123 PEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP 182
               AG L+ + DH+N M   P++G  +    ERF  +++ YD + RA ++  A+  G P
Sbjct: 121 RTFSAGDLMLIADHMNLMFRNPLIGSTEPGD-ERFPDMSDPYDRDLRARMRAAAQVVGVP 179

Query: 183 LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAE 242
           L EGV+    GP +ET +E+RM++ +G D VGMS VPEVI AR   ++ VAVS ITN A 
Sbjct: 180 LHEGVYCGLLGPTYETPSEVRMLERMGVDAVGMSTVPEVIVARALGMRAVAVSCITNKAA 239

Query: 243 GLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           GLS  KLSHA+ + A +    +F  LI  F+R++
Sbjct: 240 GLSAEKLSHAEVMEAGKAVAGHFEALITEFVRQL 273


>UniRef50_Q1NL01 Inosine guanosine and xanthosine phosphorylase:Purine nucleoside
           phosphorylase I, inosine and guanosine-specific
           (Fragment) n=3 Tax=Deltaproteobacteria
           RepID=Q1NL01_9DELT
          Length = 288

 Score =  286 bits (731), Expect = 8e-76,   Method: Composition-based stats.
 Identities = 98/270 (36%), Positives = 143/270 (52%), Gaps = 2/270 (0%)

Query: 6   FSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH 65
           F          ++ + P   P V  +LG+GLG LA  +   V I Y  +P FP +TV GH
Sbjct: 20  FYQRVEEARLYLQQHLP-APPEVVLVLGTGLGQLATMVAEPVQIPYADIPHFPRATVSGH 78

Query: 66  AGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
            G LV G L G  V  M+GR H+YEG     +T  IR   LLG   L  +NAAG L P+ 
Sbjct: 79  HGNLVCGRLCGRQVAVMQGRFHYYEGYSARELTMPIRVLSLLGARQLLVSNAAGGLNPQF 138

Query: 126 GAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF-PLT 184
             G+L+ + DH+N +P  P+ G N + +GERF  ++ AYD E R    +  +  G   + 
Sbjct: 139 APGTLMLINDHLNLIPDNPLRGANIEAWGERFPDMSVAYDRELRGRAWQSVRRLGLERVE 198

Query: 185 EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL 244
           EG++ + PGP+ ET AE R ++  G D VGMS VPEVI ARH  ++V+ V+ ++N+ +  
Sbjct: 199 EGIYAAIPGPSLETPAETRHLRQCGADAVGMSTVPEVIVARHAGMRVLGVAVVSNVNDPD 258

Query: 245 SDVKLSHAQTLAAAELSKQNFINLICGFLR 274
           +   +     +  +E   Q    L+   L 
Sbjct: 259 NFQPIRLTDIIRESEACAQRLQQLLWELLA 288


>UniRef50_C0BWU4 Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM
           15053 RepID=C0BWU4_9CLOT
          Length = 276

 Score =  285 bits (729), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 101/265 (38%), Positives = 144/265 (54%), Gaps = 3/265 (1%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
             + I+       P V  +LG+ LG +  +I +   I Y+++P F +ST  GHAG+LV G
Sbjct: 13  SAEYIREKIG-TPPAVGIVLGTCLGEIEHEITDKTEIYYKEIPNFLISTAPGHAGKLVCG 71

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L G  V+CM GR H YEG     +   +  FKLLG   L  TNAAG++      G +  
Sbjct: 72  RLGGKRVLCMAGRFHHYEGYSFEELRIPVYVFKLLGIRTLILTNAAGAVNLNYETGDICV 131

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           +KDHIN    +P  G N    GERFFS+ + Y    R L +  A E GF L EGV+   P
Sbjct: 132 IKDHINLCGVSPQRGENIPELGERFFSMNDVYTPSLRRLAKDAAVELGFSLQEGVYYFAP 191

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM-AEGLSDVKLSH 251
           GP FET AEIR M+++G D+VGMS VPE I+A HC + V+ +S  TN+ A+ + D  ++ 
Sbjct: 192 GPQFETPAEIRAMRLLGADMVGMSTVPEAITAAHCRMDVLGLSLATNLSADRVLDHDVT- 250

Query: 252 AQTLAAAELSKQNFINLICGFLRKI 276
                  ++    F  L+   + ++
Sbjct: 251 EDVNNVEDVVSGRFRALLTKIVSRL 275


>UniRef50_C1C0Q7 Purine nucleoside phosphorylase n=2 Tax=Caligus RepID=C1C0Q7_9MAXI
          Length = 299

 Score =  285 bits (729), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 97/274 (35%), Positives = 151/274 (55%), Gaps = 10/274 (3%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL 71
              D I     +  P +  I GSGLG++ D +++ V I Y  +P FP +TV  H  ++V 
Sbjct: 20  ESADYILGQISN-KPTIGIICGSGLGSIGDAVKDPVIIKYTDIPHFPTTTVGSHRSQMVF 78

Query: 72  GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
           G L G  V+ M+GR HFYEG  +   +  +R   L+G + L  TNA+G  R ++  G L+
Sbjct: 79  GTLGGAQVMVMQGRFHFYEGHSIHTCSMPVRVMHLVGVKTLISTNASGGTREDLKVGDLL 138

Query: 132 ALKDHINTM----PGTPMVGLN-DDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LT 184
            + DHIN +       P+ G N D+RFG RF ++   YD EY  L +++AK+ G    + 
Sbjct: 139 IMTDHINLLGFNGGQNPLGGANHDNRFGTRFVAMNKCYDEEYIKLARQIAKDSGLESIVK 198

Query: 185 EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG- 243
            GV+    GP++ET AE+R M+I+GGD +GMS V E I AR C ++V ++S ITN+    
Sbjct: 199 SGVYAMTGGPSYETPAEVRSMKILGGDCIGMSTVHENIVARQCGMRVFSMSLITNICVSS 258

Query: 244 -LSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
             S+ K +H + +   +  +++       FL  +
Sbjct: 259 QESEDKATHQEVIEVGQSREESLKIFTFSFLAGM 292


>UniRef50_B2KC58 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Elusimicrobium minutum Pei191 RepID=B2KC58_ELUMP
          Length = 273

 Score =  284 bits (727), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 97/263 (36%), Positives = 148/263 (56%)

Query: 14  IDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH 73
              I     +F P +A I GSGL     +++N   I Y+ +P F  STV GH+G L+ G 
Sbjct: 11  TAFINKKTKNFKPEIALITGSGLAGSVPELKNKTVIPYKNIPDFLNSTVSGHSGNLIFGT 70

Query: 74  LQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVAL 133
            +G  ++ M+GR H+YEG  +  +  A R   +LG + L  + A GS+  ++  GSL  L
Sbjct: 71  YKGKKLMVMQGRFHYYEGHCIKDIALAPRVMGMLGVKTLMVSAAVGSINAKLTPGSLAVL 130

Query: 134 KDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPG 193
            DHIN M   P++G  D  FG+ F  L+ AYD +   L+   AK+        V+++  G
Sbjct: 131 SDHINLMATNPLIGNYDPAFGQMFVDLSEAYDKKLVKLISSKAKKLKINNAPAVYIAVTG 190

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQ 253
           PNFET +EI+  + +G DVVGMSVV EVI++R   +KV   + +TN+A G+S   LSHA+
Sbjct: 191 PNFETPSEIKAFRTLGADVVGMSVVHEVIASRQAGIKVCGCAWVTNLASGISKTPLSHAE 250

Query: 254 TLAAAELSKQNFINLICGFLRKI 276
           TL+  +  +  F  L+   + ++
Sbjct: 251 TLSETKKIEGKFKTLLENVIPEM 273


>UniRef50_A9URE9 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9URE9_MONBE
          Length = 311

 Score =  282 bits (723), Expect = 7e-75,   Method: Composition-based stats.
 Identities = 106/280 (37%), Positives = 148/280 (52%), Gaps = 11/280 (3%)

Query: 7   SHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHA 66
                  +  I+T      P +  I GSGLG LA ++++AV I YE++P FPVSTV GH 
Sbjct: 24  FDLVEDAVKHIQTKA-KTQPLIGIICGSGLGGLAAEVQDAVTIGYEEIPNFPVSTVAGHE 82

Query: 67  GELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVG 126
           G+LV G L G PVV MKGR H YEG   + +   IRT   LG + LF TNAAG L     
Sbjct: 83  GKLVFGTLGGAPVVVMKGRLHCYEGYAFSRIAVPIRTLCALGIKYLFVTNAAGGLNESFE 142

Query: 127 AGSLVALKDHINTMP---GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF-- 181
            G L+ L+DH+N        P+VG +DDR+G RF  ++  YD + R + ++         
Sbjct: 143 VGDLMMLEDHLNFPGFAVQNPLVGPHDDRYGARFVPMSKPYDRKLRDIFKQTIDGMSMAG 202

Query: 182 ---PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
              P   GV+    GP +E+ AE R ++  G D VGMS VPEVI A    +K +A+S IT
Sbjct: 203 LHSPFRTGVYAMVGGPTYESPAEARFIKSAGADAVGMSTVPEVIVAIQQGVKCLAMSLIT 262

Query: 239 NMAE--GLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           N        D + +HA+ L A++  + +   L     + +
Sbjct: 263 NKVVLKIDDDNEPNHAEVLEASQARQPDVQRLFVALSKNV 302


>UniRef50_C5NWB5 Purine nucleoside phosphorylase 1 n=1 Tax=Gemella haemolysans ATCC
           10379 RepID=C5NWB5_9BACL
          Length = 274

 Score =  281 bits (720), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 95/275 (34%), Positives = 141/275 (51%), Gaps = 8/275 (2%)

Query: 6   FSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFP----VST 61
           +  N +   + I  Y  +     A +LGSG   +  ++E+   + YE +P FP     + 
Sbjct: 3   YYQNIIETANYIIKYFGEPI-DYAVVLGSG---ITLELEDQQELGYEAIPLFPGNKHANR 58

Query: 62  VHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSL 121
           V GHA +L  G + G  V+ + GR H+YEG  M  +       K LG + LF TNA G++
Sbjct: 59  VKGHANKLTFGKISGKNVLVLNGRLHYYEGYSMKDVAFMTYVVKHLGVKGLFITNACGAI 118

Query: 122 RPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF 181
                 G +V L D I+ +   P++G N+ R GERF  +   +D+     L K AK+   
Sbjct: 119 NTNFREGDIVCLDDFISLVSNNPLMGENEPRLGERFVDMTTPFDSYLVENLHKSAKKLDI 178

Query: 182 PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA 241
            L  GV+  + GP FET AEIR  + +G D+VGMS VPEVI+A H  L V  ++  TNMA
Sbjct: 179 TLHTGVYGFFQGPYFETRAEIRAFKTMGCDLVGMSTVPEVIAANHASLPVAVLACATNMA 238

Query: 242 EGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
            G+ + K  H   L  A+   +N   L+   L+ +
Sbjct: 239 TGIQEKKHDHEHVLQTAQKISENLKKLLIETLQNL 273


>UniRef50_B4D4P3 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Chthoniobacter flavus Ellin428 RepID=B4D4P3_9BACT
          Length = 265

 Score =  279 bits (714), Expect = 6e-74,   Method: Composition-based stats.
 Identities = 94/260 (36%), Positives = 142/260 (54%), Gaps = 6/260 (2%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL 71
             ++++     DF P    +LGSGLG+L ++++  +++ YE++ G PVST  GHAG  V 
Sbjct: 8   LSVEVLPKAVRDFQPEWGIVLGSGLGSLVEEVDAILSLPYEEITGMPVSTAPGHAGRFVF 67

Query: 72  GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
           G L G  V+  +GR H YEGR    +T A+R  + +G   L  TNAAG+L P+   GS +
Sbjct: 68  GRLAGCRVMMAQGRVHLYEGRTADEVTAAVRFMENIGVRRLLLTNAAGTLNPKFEPGSWM 127

Query: 132 ALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSY 191
            L DH+N    +P++G         F  ++  Y  E R      A EEG  L EGV+   
Sbjct: 128 MLNDHLNLTGTSPLLG------APNFADMSAVYSPELRVRFATAAGEEGLVLHEGVYAGL 181

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH 251
            GP +ET AE+RM++++G D VGMS V E I AR   +++ A S +TN A GL    LSH
Sbjct: 182 LGPQYETPAEVRMLRMLGADAVGMSTVLEAIQARALKMEIAAFSCLTNWAAGLGTKPLSH 241

Query: 252 AQTLAAAELSKQNFINLICG 271
            + +    ++    + ++  
Sbjct: 242 EEVIETGRVASAQMLRILTR 261


>UniRef50_Q05788 Purine nucleoside phosphorylase n=10 Tax=Saccharomycetaceae
           RepID=PNPH_YEAST
          Length = 311

 Score =  278 bits (711), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 108/295 (36%), Positives = 149/295 (50%), Gaps = 31/295 (10%)

Query: 13  CIDIIKTYKPDF--------TPRVAFILGSGLGALADQI----ENAVAISYEKLPGFPVS 60
               I                PR   I GSGLG ++ ++       V + Y+ +PGF  S
Sbjct: 17  AAAYISAILEPHFKNTTNFEPPRTLIICGSGLGGISTKLSRDNPPPVTVPYQDIPGFKKS 76

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLG-CELLFCTNAAG 119
           TV GH+G L+ G + G PVV M GR H YEG  +   T  IR    +G    L  TNAAG
Sbjct: 77  TVPGHSGTLMFGSMNGSPVVLMNGRLHGYEGNTLFETTFPIRVLNHMGHVRNLIVTNAAG 136

Query: 120 SLRPEVGAGSLVALKDHIN---TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVA 176
            +  +  A  L+ + DH+N        P+ G N D  G RF +L++AYD E R LL K  
Sbjct: 137 GINAKYQACDLMCIYDHLNIPGLAGQHPLRGPNLDEDGPRFLALSDAYDLELRKLLFKKW 196

Query: 177 KEEGF--PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAV 234
           KE     PL EG +    GP FET AE +M++++GGD VGMS VPEVI ARHC  +V+A+
Sbjct: 197 KELKIQRPLHEGTYTFVSGPTFETRAESKMIRMLGGDAVGMSTVPEVIVARHCGWRVLAL 256

Query: 235 SAITN------MAEGLSDVKL-------SHAQTLAAAELSKQNFINLICGFLRKI 276
           S ITN       A  L +  +       +HA+ L   +++  +  NLI   + ++
Sbjct: 257 SLITNTCVVDSPASALDESPVPLEKGKATHAEVLENGKIASNDVQNLIAAVMGEL 311


>UniRef50_O57865 Uncharacterized protein PH0125 n=36 Tax=Archaea RepID=Y125_PYRHO
          Length = 257

 Score =  277 bits (710), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 64/254 (25%), Positives = 109/254 (42%), Gaps = 18/254 (7%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P++  I GSG+  + +  E           G P + +        +G ++GV V  +   
Sbjct: 2   PKIGIIGGSGVYGVFEPKEVVKVH---TPYGRPSAPIE-------IGEIEGVEVAFIPRH 51

Query: 86  G--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           G  H +    +    + I     LG E +   NA GSL+ E   G +V +   I+     
Sbjct: 52  GKYHEFPPHQVPYRAN-IWALHELGVERVIAINAVGSLKEEYKPGDIVIIDQFIDFTKKR 110

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEI 202
                N  +      S+A+ +  E R +  + AKE   P+ E G +V   GP F T AE 
Sbjct: 111 EYTFYNGPK--VAHVSMADPFCPELRKIFIETAKELNLPVHERGTYVCIEGPRFSTRAES 168

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
           RM +    DV+GM++VPEV  AR   +  V +S +T+     ++  +   + L   + ++
Sbjct: 169 RMFRQF-ADVIGMTLVPEVNLARELGMCYVNISTVTDYDVW-AEKPVDAQEVLRVMKENE 226

Query: 263 QNFINLICGFLRKI 276
           +    L+   + KI
Sbjct: 227 EKVQKLLKRAIPKI 240


>UniRef50_A9BH77 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=9 Tax=Bacteria RepID=A9BH77_PETMO
          Length = 270

 Score =  275 bits (703), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 93/236 (39%), Positives = 131/236 (55%)

Query: 39  LADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMT 98
           +ADQ+EN   I Y+ +P FP STV GH G LV+G ++G+PV+ +KGR H YEG  +  + 
Sbjct: 33  IADQVENPKVIEYKDIPFFPQSTVVGHEGSLVIGTIEGIPVMILKGRFHAYEGIELKDIV 92

Query: 99  DAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFF 158
             I   K LG + L  TNAAG +      G +V   D IN     P+ G N D FG RF 
Sbjct: 93  FPIYVMKDLGVKGLIITNAAGGINKTFSPGDIVVDVDFINFTFKNPLRGPNLDEFGPRFP 152

Query: 159 SLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVV 218
           SL    D  +   + +  K++   L EG ++   GP++ET +EIRM      D+VGMS +
Sbjct: 153 SLVEPVDKNWVKSVIEKCKKDNIELKEGTYLWTLGPSYETPSEIRMFDKYEADLVGMSTL 212

Query: 219 PEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLR 274
           PEV++A H  LKV++ SA+TNMA G+    L H   L   E  K  F  ++   ++
Sbjct: 213 PEVMAANHVGLKVISFSAVTNMAAGILPQPLKHEDVLRITEKIKGKFEKVVYNAIK 268


>UniRef50_B6K0G6 Purine nucleoside phosphorylase n=1 Tax=Schizosaccharomyces
           japonicus yFS275 RepID=B6K0G6_SCHJY
          Length = 319

 Score =  275 bits (703), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 102/302 (33%), Positives = 149/302 (49%), Gaps = 26/302 (8%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDF--TPRVAFILGSGLGALADQIENAV-AISYEKLPGF 57
           +   +   N     + +    P     PRVA + GSGLG+LA+ +      I Y  +PGF
Sbjct: 18  IPHSETYKNAQLAREYVLANVPGELAKPRVAVVCGSGLGSLAENLFGPKFVIPYSDIPGF 77

Query: 58  PVSTVHGHAGELVLGHLQG--VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCT 115
               + GHA  L+   +    VP +   GR H YEG  + ++T   R  K++G E++  T
Sbjct: 78  VACHIPGHASRLIFAFIGENKVPCMIFAGRFHSYEGHALDVVTFPQRFMKIMGVEVMIAT 137

Query: 116 NAAGSLRPEVGAGSLVALKDHINT---MPGTPMVGLNDDRFGERFFSLANAYDAEYRALL 172
           NAAG L      G L+ +KDHIN        P+ G N D FG RF  L++AYD E R L+
Sbjct: 138 NAAGGLNSNYKVGELMIIKDHINFPGLAGLNPLKGPNLDDFGTRFPPLSDAYDLELRKLV 197

Query: 173 QKVAKEEGFP--LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLK 230
            K A E      + EG +    GP+FET AE RM++++G D VGMS VPEVI ARHC ++
Sbjct: 198 YKAATERDVHRTINEGCYAFVSGPSFETRAEARMLKLLGADCVGMSTVPEVIVARHCGIR 257

Query: 231 VVAVSAITNMAE----------------GLSDVKLSHAQTLAAAELSKQNFINLICGFLR 274
           V+A+S +TN                    +S    +H + L A   + ++   L+   + 
Sbjct: 258 VLAISLVTNNVVTEESPSALSTPDADTSIMSKGAANHKEVLEAGLAAAEDMRILVTTVIN 317

Query: 275 KI 276
            +
Sbjct: 318 HL 319


>UniRef50_B3QTH8 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Chloroherpeton thalassium ATCC 35110
           RepID=B3QTH8_CHLT3
          Length = 292

 Score =  275 bits (703), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 91/263 (34%), Positives = 139/263 (52%), Gaps = 4/263 (1%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            +  I ++       VA +LGSGLGA A +++   +    ++P FP  +V GH G +  G
Sbjct: 30  AVKHIHSHCDVPKNTVAIVLGSGLGAFASRVKVYHSFKTSEIPHFPTPSVEGHGGRVTFG 89

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            L   PV  ++GR H YEG  +  +T  +   + LG ++L  TN+AG + P+   G L  
Sbjct: 90  TLGDRPVALIEGRVHLYEGWPVEWVTFYVEILRQLGIKVLILTNSAGGINPDFNVGDLCL 149

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           ++DHIN M  T +     +    R       YD +   ++ + A E    L +GV+    
Sbjct: 150 IRDHINFMFETRLNRYGMEP-RLRHVGF---YDKDLSEVIYRTANECKITLRQGVYAGVK 205

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP +ET AEIRM+Q  G D+VGMS VPEV++A    ++V AVS +TN A G+S+ KLSH 
Sbjct: 206 GPCYETKAEIRMLQACGADLVGMSTVPEVVAANFHHMRVAAVSLVTNKATGISECKLSHD 265

Query: 253 QTLAAAELSKQNFINLICGFLRK 275
                AE +++ F   +   + K
Sbjct: 266 DVKKTAESAREKFDYFLEMVINK 288


>UniRef50_B1GZW7 Purine nucleoside phosphorylase n=1 Tax=uncultured Termite group 1
           bacterium phylotype Rs-D17 RepID=B1GZW7_UNCTG
          Length = 281

 Score =  273 bits (699), Expect = 4e-72,   Method: Composition-based stats.
 Identities = 90/272 (33%), Positives = 138/272 (50%), Gaps = 1/272 (0%)

Query: 3   QVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTV 62
           ++            I +   DF P  A I GSGLG ++ Q      I Y  +P F  + V
Sbjct: 2   KLNIFKKIQETKKTILS-LHDFNPTTAVIAGSGLGEISKQFTIRKTIKYSDIPYFLKTAV 60

Query: 63  HGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLR 122
            GHAG+L+L       ++   GR H+YEG     +   +R  K LG + L  T A G L 
Sbjct: 61  QGHAGDLLLCSYGSADLLIFNGRFHYYEGHHPQEVVYPVRVMKFLGIKTLVITAATGGLN 120

Query: 123 PEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP 182
            +   G ++ LKDHI+     P++G++ D FGERF ++ N YDA  R     +AK+    
Sbjct: 121 KKYSVGDIIVLKDHIDCTGNNPLIGVHYDEFGERFPNMENVYDAVLRKKALSLAKKFKIK 180

Query: 183 LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAE 242
             EG++    GP++ET A ++  QI+GGDVVGMSVV E   A    ++V+ ++ ++NMA 
Sbjct: 181 ACEGIYFGVSGPSYETPASVKAYQILGGDVVGMSVVYEATVAAQMKMRVLGLAYVSNMAA 240

Query: 243 GLSDVKLSHAQTLAAAELSKQNFINLICGFLR 274
           G+ +  LSHA+ +   E    +   +    + 
Sbjct: 241 GIHNRPLSHAEVIENGEKVSLSMSKIAKNIIS 272


>UniRef50_Q9UTG1 Putative purine nucleoside phosphorylase n=4 Tax=Ascomycota
           RepID=PNPH_SCHPO
          Length = 315

 Score =  272 bits (697), Expect = 7e-72,   Method: Composition-based stats.
 Identities = 103/293 (35%), Positives = 144/293 (49%), Gaps = 26/293 (8%)

Query: 10  PLFCIDIIKTYKPDF--TPRVAFILGSGLGALADQIENAV-AISYEKLPGFPVSTVHGHA 66
            L   + I    P+    P+VA I GSGLG LA  +   V  + YE +P F VS V GHA
Sbjct: 23  ALEAREYIIEQVPEELSKPKVAIICGSGLGTLASGLSAPVYEVPYEDIPHFHVSHVPGHA 82

Query: 67  GELVLGHLQGVPV--VCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPE 124
            +L    L    V  + + GR H YEG  +   T  +R  K++G E++  TNAAG L   
Sbjct: 83  SKLYFAFLGEKRVPTMILAGRYHSYEGYPIEATTFPVRLMKVMGVEVMVVTNAAGGLNQG 142

Query: 125 VGAGSLVALKDHINT---MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAK--EE 179
              G L+ LKDHIN        P+ G N   FG RF  L++AYD E R L+   AK  + 
Sbjct: 143 FKVGDLMILKDHINFPGLAGMNPLRGPNAHEFGVRFPPLSDAYDLELRKLVYDAAKAHKV 202

Query: 180 GFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
              + EG +    GP FET AE RM+ ++G D VGMS VPEV+ ARHC ++V+A+S +TN
Sbjct: 203 SRTIHEGCYAFVSGPCFETRAESRMLALMGADCVGMSTVPEVVVARHCGIRVLAISLVTN 262

Query: 240 M----------------AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
                            +  +S    +H + L     +  +   ++   +  I
Sbjct: 263 NVVVEESPSAKDLVEVDSNVMSKGAANHLEVLEVGIAAAADVRTMVETIVNFI 315


>UniRef50_A9G8Q6 DeoD protein n=8 Tax=Bacteria RepID=A9G8Q6_SORC5
          Length = 283

 Score =  270 bits (692), Expect = 2e-71,   Method: Composition-based stats.
 Identities = 90/238 (37%), Positives = 133/238 (55%)

Query: 39  LADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMT 98
             D++   V + Y  +PG P   V GH G L  G +  V V C++GR H YEG  +  + 
Sbjct: 35  WGDELAELVKVPYADIPGMPRPAVAGHPGFLCAGRVGDVQVACLQGRAHVYEGHPLAKVV 94

Query: 99  DAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFF 158
             +R    LGC  +  TNAAG + P   AG L+ L DH+N M   P+VG ND+  G+RF 
Sbjct: 95  FGVRVLARLGCRAVLLTNAAGGINPGFAAGDLMLLTDHLNLMGANPLVGPNDEALGKRFP 154

Query: 159 SLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVV 218
            +  A+D     L +  A + G  L EGV+ +  GP +ET AEIRM++ +G D VGMS V
Sbjct: 155 DMTYAHDPRLLELAKTAASDAGVALREGVYAALLGPTYETPAEIRMLRTLGADAVGMSTV 214

Query: 219 PEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           PE+I+ RH  +   A+S +TN+A GL+  +L H +    A  ++  F  L+  ++R++
Sbjct: 215 PEIIALRHMGVPAAAISCVTNLAAGLTKRELDHKEVEETAREARARFTALLSAWVRRV 272


>UniRef50_Q472Z5 Purine nucleotide phosphorylase:Inosine guanosine and xanthosine
           phosphorylase n=1 Tax=Ralstonia eutropha JMP134
           RepID=Q472Z5_RALEJ
          Length = 287

 Score =  269 bits (688), Expect = 8e-71,   Method: Composition-based stats.
 Identities = 152/276 (55%), Positives = 190/276 (68%)

Query: 2   SQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVST 61
           S           +  I+ +  +F P++  ILGSGLG LA  IENA+AI Y  LPGFP S 
Sbjct: 7   SSADAPDQTEQAVQRIRQHVGEFRPQIGLILGSGLGGLARAIENAIAIPYAALPGFPQSL 66

Query: 62  VHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSL 121
           V GHAGE+VLG L GV ++CM+GR HFYEG G T MT A+RT K +GC+ LF T AAGSL
Sbjct: 67  VEGHAGEVVLGRLGGVELMCMRGRQHFYEGHGTTGMTQAVRTMKRMGCDRLFVTCAAGSL 126

Query: 122 RPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF 181
            PE+  G LVA+KDHIN +PG P++G NDD+ G RF S+ANAYD   R  LQ VA+  G 
Sbjct: 127 HPELEPGRLVAIKDHINLLPGNPLIGPNDDQIGPRFCSMANAYDTVLRQGLQDVAQALGL 186

Query: 182 PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA 241
           P  EGV+V++ GP FETAAEIRMMQ+IGGDVVGMS VPEVISARHC L+V+A++ ITN+ 
Sbjct: 187 PWAEGVYVAFSGPTFETAAEIRMMQVIGGDVVGMSTVPEVISARHCGLRVLAIACITNLG 246

Query: 242 EGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           EG+ +  LSH  TL    ++  +   LI G+  + A
Sbjct: 247 EGIGNEVLSHELTLQYGSMALVDLQRLIVGWFEQQA 282


>UniRef50_Q11C51 Inosine guanosine and xanthosine phosphorylase family n=10
           Tax=Alphaproteobacteria RepID=Q11C51_MESSB
          Length = 268

 Score =  269 bits (688), Expect = 8e-71,   Method: Composition-based stats.
 Identities = 114/265 (43%), Positives = 159/265 (60%), Gaps = 3/265 (1%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            IDI+        PR+A +LGSGLGALAD++   V I Y  LPGFP+S V GHAGELV G
Sbjct: 4   TIDILIERLNGLAPRLAIVLGSGLGALADELTKPVHIPYADLPGFPLSGVSGHAGELVAG 63

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
           +   VPV+ + GR H+YE      M  A+     +G   +  TNAAGSL+ ++ AGS++ 
Sbjct: 64  YFGSVPVIMLAGRSHYYEHGNAAAMRPALEVLAGIGVTAIILTNAAGSLQVDMPAGSVML 123

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP 192
           ++DHIN     P++G   +    RF  ++ AYD + R  L++ A + G  L +GV++ + 
Sbjct: 124 VEDHINYSGMNPLIGEQSEA---RFVGMSAAYDRDLRDALERAASKAGETLHKGVYMWFS 180

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP+FET AEIRM +++G D VGMS VPEVI AR   L+V A S ITN+A GL   +LSH 
Sbjct: 181 GPSFETPAEIRMARMLGADAVGMSTVPEVILARFLGLRVAACSVITNLAAGLGAGELSHD 240

Query: 253 QTLAAAELSKQNFINLICGFLRKIA 277
           +T   A +       ++  F+R  A
Sbjct: 241 ETKDMAPVGGGKLAKILTQFMRDSA 265


>UniRef50_B8J4B5 Inosine guanosine and xanthosine phosphorylase family n=7
           Tax=Desulfovibrionales RepID=B8J4B5_DESDA
          Length = 303

 Score =  268 bits (686), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 93/258 (36%), Positives = 137/258 (53%), Gaps = 9/258 (3%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH---------LQGVP 78
           V  +LG+GL  LAD++   VA+ Y  LPGFPVS+V  H G  V G          + G P
Sbjct: 46  VGLVLGTGLSGLADRLAERVAVPYADLPGFPVSSVDSHVGAFVWGRFPSSCGEDDVPGRP 105

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           V+  +GR H YEGR    +   +R    +G + L  TNAAG+L P   AGS++ + D IN
Sbjct: 106 VLIQQGRCHLYEGRSPAEVCMGVRVMAAMGVKTLVITNAAGALNPHFDAGSIMCMSDFIN 165

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFET 198
               +P++G N +++G RF  ++  +DA+ R L  + +   G  L  GV++   GP  ET
Sbjct: 166 HTGYSPLLGCNCEQWGPRFPDMSAPFDADLRTLAMETSARLGLRLERGVYIGVRGPEMET 225

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
            AE RM +  G D VGMS V EVI+ARH  ++V+ +S I+N             + +  A
Sbjct: 226 PAETRMYRQWGADAVGMSTVLEVIAARHLGMRVLGLSCISNKNLPDCMTPAPLEEIILVA 285

Query: 259 ELSKQNFINLICGFLRKI 276
             + +N   LI   + K+
Sbjct: 286 AQAGKNLGRLIRAMMTKL 303


>UniRef50_Q11M20 Inosine guanosine and xanthosine phosphorylase family n=2
           Tax=Alphaproteobacteria RepID=Q11M20_MESSB
          Length = 279

 Score =  266 bits (680), Expect = 6e-70,   Method: Composition-based stats.
 Identities = 92/250 (36%), Positives = 130/250 (52%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
            V  ILGSGLG LA  +++A  I Y ++  FPV T  GH G+LV+G L G  V  M+GR 
Sbjct: 25  EVGIILGSGLGDLAQSVDDAEVIPYTEIEAFPVPTAPGHKGQLVIGTLHGRRVAVMQGRL 84

Query: 87  HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
           H YEGR    +       K LG   L  TNAA  L P    G ++ ++DH+N     P+V
Sbjct: 85  HLYEGRSPQDIALGPYLLKRLGSASLIVTNAASGLHPAYRPGDVMLIEDHLNFTGLNPLV 144

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQ 206
           G N    G RF  ++ AYD     L ++ A+    P+ +G++    GP+ ET AE R ++
Sbjct: 145 GSNSPEIGLRFPDMSRAYDPALLDLAEEAAERALQPVHKGIYGGILGPSLETLAERRFLR 204

Query: 207 IIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFI 266
             G D VGMS V EVI+A H  L+V+ +SAITN A        +  + L +A    +   
Sbjct: 205 ASGCDAVGMSTVTEVIAAVHGGLRVIGISAITNTAAIGDRRTDTIEEALTSAANCAEKID 264

Query: 267 NLICGFLRKI 276
            ++   L  +
Sbjct: 265 AILRQLLPLL 274


>UniRef50_C7NVB1 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Halorhabdus utahensis DSM 12940 RepID=C7NVB1_HALUD
          Length = 275

 Score =  265 bits (677), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 95/266 (35%), Positives = 139/266 (52%), Gaps = 4/266 (1%)

Query: 14  IDIIKTYKPD---FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
            D +          TP  A ILGSGLG + D++E  +++ YE +P    STV GHAG  V
Sbjct: 5   ADYLSEQLQANDLLTPETAMILGSGLGGMTDEMEIELSVPYEDVPTLEASTVEGHAGRFV 64

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
           +G +  V V+ M GR H+YE   M  +   IR    LGCE L  TNAAG +  +   G +
Sbjct: 65  VGTVGEVSVLGMDGRVHYYETGDMDPIVAPIRALGELGCERLLITNAAGGINADYEPGDV 124

Query: 131 VALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFV 189
           + ++DHIN     P++G      G  F  + NAY  +  A  + +A +    + + GV+ 
Sbjct: 125 MLIEDHINMQGTNPLIGRAGLGDGPMFPDMTNAYSPDLLAAARDLAADSSLTIHDGGVYA 184

Query: 190 SYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKL 249
             PGP++ET AEI M+  +G D VGMS VPEVI A    + VV +S ITN A G+    L
Sbjct: 185 GMPGPSYETPAEIEMLDTVGADAVGMSTVPEVIVANQLGMDVVGMSTITNYAAGVVGDPL 244

Query: 250 SHAQTLAAAELSKQNFINLICGFLRK 275
           SH + +   +  + +    +   L++
Sbjct: 245 SHEEVVETIKTIEDDLRTYVTALLQR 270


>UniRef50_B4MDV7 GJ18292 n=4 Tax=Drosophila RepID=B4MDV7_DROVI
          Length = 325

 Score =  261 bits (668), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 92/261 (35%), Positives = 133/261 (50%), Gaps = 7/261 (2%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           + +  P+   + GS L  L D IEN + I Y  +P FP  T+H H G+L +G L G  V+
Sbjct: 63  RSETRPKFGLVCGSNLDTLTDLIENPIVIDYSDIPKFPDCTIHDHKGKLFVGTLMGATVI 122

Query: 81  CMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINT- 139
            ++GR H YEG  +   +  +R  KL G E +  T AAG++      G ++ +KDHIN  
Sbjct: 123 ALQGRFHHYEGNSLASCSMPVRVLKLCGIEYMILTCAAGAVNKNYKVGDIMLIKDHINMF 182

Query: 140 --MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF--PLTEGVFVSYPGPN 195
                 P+ G ND RFG+R   +A+AYD        ++  E G    +  GV+    GP 
Sbjct: 183 GWFGNNPLNGPNDLRFGDRHVIMADAYDEGLIEKALEIGLEIGQEDRMHLGVYACLGGPV 242

Query: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL 255
           +ETA E R ++ IG D VGMS+V EVI ARHC LKV + S I+       D+  S     
Sbjct: 243 YETATEQRFLRSIGVDAVGMSLVQEVIYARHCGLKVFSFSLISMPPIEQPDMPESVRDV- 301

Query: 256 AAAELSKQNFINLICGFLRKI 276
            +    +   + L+   + KI
Sbjct: 302 -SIHQGQIVCMELLSRMIYKI 321


>UniRef50_Q13126 S-methyl-5'-thioadenosine phosphorylase n=55 Tax=cellular organisms
           RepID=MTAP_HUMAN
          Length = 283

 Score =  260 bits (666), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 58/263 (22%), Positives = 105/263 (39%), Gaps = 16/263 (6%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
                 ++  I G+GL    + +E       +   G P       +  L+LG ++ V  V
Sbjct: 5   TTTTAVKIGIIGGTGLDD-PEILEGRTEKYVDTPFGKP-------SDALILGKIKNVDCV 56

Query: 81  CMKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
            +   G  H      +    + I   K  GC  +  T A GSLR E+  G +V +   I+
Sbjct: 57  LLARHGRQHTIMPSKVNYQAN-IWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFID 115

Query: 139 TMPGTPMVGLNDDRF---GERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGP 194
                P    +       G     +A  +  + R +L + AK+ G     +G  V+  GP
Sbjct: 116 RTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGP 175

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS-DVKLSHAQ 253
            F + AE  M +  G DV+ M+ VPEV+ A+   +   +++  T+       +  +S  +
Sbjct: 176 RFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDR 235

Query: 254 TLAAAELSKQNFINLICGFLRKI 276
            L   + +     +L+   + +I
Sbjct: 236 VLKTLKENANKAKSLLLTTIPQI 258


>UniRef50_Q2S0P3 Purine nucleoside phosphorylase n=1 Tax=Salinibacter ruber DSM
           13855 RepID=Q2S0P3_SALRD
          Length = 262

 Score =  259 bits (661), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 86/250 (34%), Positives = 135/250 (54%), Gaps = 1/250 (0%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P +A ILGSGLG LA+  +    +   ++PG+P STV GH+G+LV G L+   VV ++GR
Sbjct: 9   PEMALILGSGLGRLAEAADETTVVPAAEIPGYPESTVEGHSGKLVFGALEDTRVVFVQGR 68

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H YEG  +  +   +R    LG + +  TN+AG +      G+L+ +  H+N    +P 
Sbjct: 69  VHLYEGYPVQKIAMPVRLVHALGADRMLVTNSAGGINRTFDPGTLMFITSHLNMAFASPG 128

Query: 146 VGLNDDRFGERFFSLANA-YDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           VG       +R        Y+  + +  ++VA + G     G +    GP++ET AE+R 
Sbjct: 129 VGAGAGPARQRSDEEQAPFYEPGWTSRAEQVALDLGLDARRGTYAWTLGPSYETKAEVRA 188

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           ++ +G D VGMS VPEVI A    + V+ +S ITN A GL+   L H + L  +E  + +
Sbjct: 189 LEQLGADAVGMSTVPEVIQAHQLGMAVLGLSTITNPAAGLAPGGLDHDEVLEVSERVRGD 248

Query: 265 FINLICGFLR 274
            + L+ G +R
Sbjct: 249 LMKLVRGIVR 258


>UniRef50_B9ZYX1 Nucleoside phosphorylase n=1 Tax=Dicyema japonicum
           RepID=B9ZYX1_9METZ
          Length = 282

 Score =  258 bits (660), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 93/283 (32%), Positives = 143/283 (50%), Gaps = 8/283 (2%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           MS+     +    ++ +++      P V  + G+GLG + + I +   + +  +P  P +
Sbjct: 1   MSKKIVYEDIQEMVEFVQSKMT-IRPTVGIVCGTGLGGINEVINDKEIVKFSDIPNLPQT 59

Query: 61  TVHGHAGELVLGHL-QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAG 119
           TV  HAG+ VLG L  G  V+  +GR HFYEG   +I+   IR  KL+G E L  TNAAG
Sbjct: 60  TVTSHAGQFVLGRLPCGKEVMVQQGRYHFYEGHDQSIIVAPIRMMKLMGVETLILTNAAG 119

Query: 120 SLRPEVGAGSLVALKDHI---NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVA 176
            L      G ++ +KDHI        +P+VG ND RFGERF  + N YD E R  + K A
Sbjct: 120 GLNQSYSIGDIMVIKDHIYFPGFAGNSPLVGPNDKRFGERFPPIYNLYDRELRKKMLKCA 179

Query: 177 KEEGFP-LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVS 235
           ++ G   +  G++ S  GP++ET  ++R +   G D VGMS   E I   H  LKVVA+S
Sbjct: 180 EQLGMDFVRHGIYASVAGPHYETIFDMRFLLKNGCDAVGMSTSGEAICGAHIGLKVVAMS 239

Query: 236 AITNMAEGLSDVK--LSHAQTLAAAELSKQNFINLICGFLRKI 276
            ++N      +V+  +   +              L+  F+ ++
Sbjct: 240 GVSNKFVDSEEVENFVDGDEVTQVVNNGVSYVSKLLERFISEL 282


>UniRef50_C5P2F4 Purine nucleoside phosphorylase, putative n=2 Tax=Coccidioides
           RepID=C5P2F4_COCP7
          Length = 344

 Score =  256 bits (654), Expect = 6e-67,   Method: Composition-based stats.
 Identities = 110/342 (32%), Positives = 156/342 (45%), Gaps = 70/342 (20%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDF--TPRVAFILGSGLGALADQIENA--VAISYEKLPG 56
           M++          ++ +K + P+   TPRVA I GSGLG LAD I++   V   Y  +P 
Sbjct: 1   MAESSMFKQAQAALNYLKPHLPEALRTPRVAVICGSGLGGLADTIDSKAKVEFDYRDIPN 60

Query: 57  FPVSTVHGHAGELVLGHLQ-GVPVVCMKGRGH---------FYEGRGMTIMTDAIRTFKL 106
           FP STV GH G+LV G+L    P V M GR           FYEG  +  +T  +R FKL
Sbjct: 61  FPASTVPGHLGKLVFGYLGAETPAVLMVGRAQEIEADTAASFYEGHSIDKVTFPVRLFKL 120

Query: 107 LGCELLF----------------------CTNAAGSLRPEVGAGSLVALKDHI---NTMP 141
           LG E++                        TNA+G L  E   G +V + DHI       
Sbjct: 121 LGVEIMIGTGNEHLLGKHKIQSPTKQLCTVTNASGGLNSEYAVGDVVLINDHIFLAGLAG 180

Query: 142 GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAK-----EEGFPLTEGVFVSYPGPNF 196
             P+ G N+D FG RF +L++AYD E R    +        E    + EGV+    GP  
Sbjct: 181 LHPLRGPNEDEFGVRFPALSDAYDLELRRTAHRAWTKVIRVESKRRIHEGVYAFCAGPR- 239

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAE-------------- 242
              AE R ++ +G D+VGMS VPE+I ARHC L+V+A+S +TN A               
Sbjct: 240 ---AECRFLRQLGADLVGMSTVPEIIVARHCGLRVLALSLVTNNAVLTPVPRGDDRLLQE 296

Query: 243 --------GLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
                    + + K +H + L A   +  +   L+   +  +
Sbjct: 297 TERAQLNRIVEEGKANHEEVLKAGSQAAADVQKLVRQVVLDM 338


>UniRef50_Q7ZV22 Methylthioadenosine phosphorylase n=20 Tax=Metazoa
           RepID=Q7ZV22_DANRE
          Length = 280

 Score =  255 bits (653), Expect = 9e-67,   Method: Composition-based stats.
 Identities = 58/257 (22%), Positives = 101/257 (39%), Gaps = 16/257 (6%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I GSGL    D +E           G P       +  L+LG ++ V  V +   G
Sbjct: 8   KIGIIGGSGLDD-PDILEGRTERYVVTPYGKP-------SDALILGKIKNVDCVLLARHG 59

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + I   K  GC  L  T A GSLR ++  G +V +   I+      
Sbjct: 60  RQHTIMPTNVNYQAN-IWALKEEGCTHLLVTTACGSLREDIQPGDIVLIDQFIDRTTKRV 118

Query: 145 MVGLND---DRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAA 200
               +       G     +A  + ++ R +L +VA+  G      G  V+  GP F + A
Sbjct: 119 QTFYDGQPTSPPGVCHIPMAEPFCSKTREVLLEVAQGLGVKCHTRGTMVTIEGPRFSSRA 178

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS-DVKLSHAQTLAAAE 259
           E  M +  G DV+ M+ VPEV+ A+   L   +++  T+       +  +     L   +
Sbjct: 179 ESLMFRQWGADVINMTTVPEVVLAKEAGLCYASIAMATDYDCWKEHEEAVCVDNVLKTMK 238

Query: 260 LSKQNFINLICGFLRKI 276
            +     +++   + +I
Sbjct: 239 ENANKASSILLTAIPQI 255


>UniRef50_D2L8K6 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Desulfovibrio sp. FW1012B RepID=D2L8K6_9DELT
          Length = 300

 Score =  255 bits (653), Expect = 9e-67,   Method: Composition-based stats.
 Identities = 93/291 (31%), Positives = 137/291 (47%), Gaps = 26/291 (8%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL 71
                 +   P     V  + G+GLG +A ++E+   ++   +PGFP +T  GHAG LV 
Sbjct: 10  AAAAATERLGPLPAGAVGLVAGTGLGGIAGKLEHCRDMATGDIPGFPAATAPGHAGRLVY 69

Query: 72  GHLQ--------------------------GVPVVCMKGRGHFYEGRGMTIMTDAIRTFK 105
           G +                             PV  + GR H YEG     +   +R   
Sbjct: 70  GTMGTACPPGDPQGSIEETMPAAGAGPDGSSRPVALLSGRLHLYEGHSPRDVAFGVRLLA 129

Query: 106 LLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYD 165
            LG   L  TNAAG+L P   AG L+ + DH+N     P+VG NDD  G RF  ++ AY 
Sbjct: 130 ALGVRQLILTNAAGALDPHFTAGGLMRVTDHLNLTGRNPLVGPNDDALGPRFPDMSRAYS 189

Query: 166 AEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISAR 225
               A+    A   G  L  GV+    GP+ ET AE RM++++G D VGMS V EVI+AR
Sbjct: 190 PRLGAVADACALSLGLRLERGVYAGVLGPSLETPAETRMLRLLGADAVGMSTVTEVIAAR 249

Query: 226 HCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           H  ++V+AVS +TN+       + +    LA A+ ++ +   L+   +  +
Sbjct: 250 HLGMEVLAVSCLTNVNLPDCMAETTLEAVLATAKRAEGDLARLLAAVIPAV 300


>UniRef50_Q3A2Z8 Xanthosine phosphorylase n=1 Tax=Pelobacter carbinolicus DSM 2380
           RepID=Q3A2Z8_PELCD
          Length = 273

 Score =  254 bits (649), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 90/272 (33%), Positives = 135/272 (49%), Gaps = 4/272 (1%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           M  V    N    ++ +          +A ILGSGLG +AD +E+     Y     FP  
Sbjct: 1   MGSVLTEENLGPIVEEVHARCGMAPFDLALILGSGLGQVADAVEDVKVWEYRDFSCFPAV 60

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
            V GHAG L+ G L G  V+  +GR H Y+G         +R    LGC  L  TNA G 
Sbjct: 61  AVAGHAGRLLAGTLHGRRVLIFQGRFHLYQGLTAWQTAVPVRLAHALGCRRLLLTNAVGG 120

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           + P++ AG  + + DHIN +   P+ G+     G+ F  L+  Y  +    L+  A    
Sbjct: 121 IHPDLDAGCFMFVADHINVLGDNPLRGM----CGDTFVDLSRLYRTDLFKSLRTEALSHN 176

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
             + +GV  + PGP++ET AE+R ++ +G D V MS++PE I A    L+VV +S++TN 
Sbjct: 177 IHVQQGVLAAVPGPSYETPAEVRALRQMGADAVSMSLIPEAIMAGALGLEVVGLSSVTNR 236

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGF 272
           A GL   +L H + LA+   + +N   L+   
Sbjct: 237 AAGLGTKRLCHDEVLASGSNTAKNLSVLVASL 268


>UniRef50_B7GAT6 Predicted protein (Fragment) n=2 Tax=Bacillariophyta
           RepID=B7GAT6_PHATR
          Length = 262

 Score =  254 bits (649), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 90/262 (34%), Positives = 133/262 (50%), Gaps = 11/262 (4%)

Query: 26  PRVAFILGSGLGALADQIENAV-AISYEKLPGFPV-STVHGHAGELVLGHLQGVPVVCMK 83
           P V  I GSGL  LA  ++     + Y  +PGFP   TV GH GE+V G + GV  +C +
Sbjct: 1   PTVGIICGSGLSGLAATLDGPTLTVPYADIPGFPAHCTVAGHKGEVVFGSIHGVQAICFR 60

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHI---NTM 140
           GR H YEG  M  +   +   + L  +++  TNAAG L P+   G +VA+ DH+      
Sbjct: 61  GRFHSYEGHDMKTVVLPVYVMRCLDTKIVIITNAAGGLNPDYNVGDVVAVSDHLALPQLA 120

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP---LTEGVFVSYPGPNFE 197
              P++G NDD  G RF + ++AY    R      A+           G +    GP +E
Sbjct: 121 GKNPLIGPNDDELGPRFPATSDAYPDALRIAATHAAESLNMQEYWHPHGTYCFVSGPMYE 180

Query: 198 TAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK---LSHAQT 254
           + AE R+++ +GGD VGMS +PEV++A HC+LKV+ +S ITN      D      +HA+ 
Sbjct: 181 SKAECRLLRTLGGDAVGMSTIPEVVAAHHCELKVLCLSLITNKVVMEGDEGATVATHAEV 240

Query: 255 LAAAELSKQNFINLICGFLRKI 276
           L A +        L+   +  +
Sbjct: 241 LEAVQARSVQMQTLVKEIVANL 262


>UniRef50_D2QX63 Inosine guanosine and xanthosine phosphorylase family n=1
           Tax=Pirellula staleyi DSM 6068 RepID=D2QX63_9PLAN
          Length = 279

 Score =  254 bits (648), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 102/279 (36%), Positives = 156/279 (55%), Gaps = 5/279 (1%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS 60
           M+ +    +       I+ +  + TPRVA ILG+GLG LA +IE A  I Y+++PGFP S
Sbjct: 1   MNPLLSRASIALAAAEIRKHYTE-TPRVAVILGTGLGGLASEIEAAAEIPYKQIPGFPHS 59

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           T   H G L+LG+L G+P   + GR HFYEG  +  +       + LGC+ L  +NAAG 
Sbjct: 60  TAPAHKGRLLLGNLLGLPCAMLAGRCHFYEGYQLEQLMFPTLVMRELGCQYLIVSNAAGG 119

Query: 121 LRPEVGAGSLVALKDHINTM--PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE 178
           + P    G ++ + DHIN M   G+  V        ERF    + YD    ++ +  A +
Sbjct: 120 VNPLYETGDVMLMDDHINLMYFKGSVAVPAASPERVERF--QEHLYDRALLSMAESAAIQ 177

Query: 179 EGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
           EGF    GV+V+  GP +ET AE R+ + IGGDVVGMS VPEV++A    ++V+ +S +T
Sbjct: 178 EGFIPKRGVYVAVSGPTYETRAEYRLFRRIGGDVVGMSTVPEVLAATSVGMRVMGISTVT 237

Query: 239 NMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
           N+A+  +   +S  + +  AE  +    +++ G + +IA
Sbjct: 238 NVAKPDAMQTVSSDEVIDVAERVQHKVRSIVRGVIERIA 276


>UniRef50_A3DD28 Methylthioadenosine phosphorylase n=7 Tax=Clostridia
           RepID=A3DD28_CLOTH
          Length = 268

 Score =  254 bits (648), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 56/261 (21%), Positives = 102/261 (39%), Gaps = 20/261 (7%)

Query: 23  DFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM 82
           ++   +    GSG  +    +EN   I  E   G P       + ++ +   +G  +  +
Sbjct: 2   NYKADIGVFGGSGFYSF---LENVEEIEMETPYGKP-------SDKIAIATYEGKRIAFL 51

Query: 83  KGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
              G  H +    +    + +   K LG + +    ++GSLR ++  G  V     ++  
Sbjct: 52  PRHGKNHQFPPHMIPYRAN-LYAMKKLGVKKILAPTSSGSLRADIKPGDFVICDQFVDRT 110

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETA 199
            G      +      +  S A+ Y  E R +  +V K+ G    E G  V   GP F T 
Sbjct: 111 TGRKDTFYDGPVT--KHISSAHPYCPELRKIAIQVGKDLGITTHEKGTVVVIQGPRFSTV 168

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD----VKLSHAQTL 255
           AE R    +G DV+ M+  PEV  AR   +    ++ IT+   GL        ++    L
Sbjct: 169 AESRWFSKMGWDVINMTQYPEVYLARELGICYANIALITDYDAGLEGRDDIEPVTEEAVL 228

Query: 256 AAAELSKQNFINLICGFLRKI 276
                + +   N++   +++I
Sbjct: 229 KVFAENNEKVKNMLFEVIKRI 249


>UniRef50_B0D4C6 Predicted protein n=3 Tax=Agaricales RepID=B0D4C6_LACBS
          Length = 315

 Score =  253 bits (647), Expect = 4e-66,   Method: Composition-based stats.
 Identities = 98/301 (32%), Positives = 139/301 (46%), Gaps = 37/301 (12%)

Query: 13  CIDIIKTYKPD--FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
            ++ I ++ P     P +  I GSGL  LA+     V + YE +PGF  S+V GH   L 
Sbjct: 12  TLEAITSFLPLNLQRPNLGIICGSGLSGLAEDFRQVVIVPYEMIPGFGHSSVPGHKSALA 71

Query: 71  LGHLQ---GVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGA 127
            G L    GVPVV M GR H YEG  M+ +   +R    LG + L  TNAAGSL P +  
Sbjct: 72  FGLLGPGEGVPVVAMLGRFHPYEGHSMSTVIFPVRVMAKLGIKDLIITNAAGSLNPNIPV 131

Query: 128 GS----LVALKDHI---NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           G+    LV ++DHI   N     P++G        RF  L+NAY    R L    A +  
Sbjct: 132 GTRKSFLVVIQDHIALPNLTGMNPLLGPQISSDVPRFLPLSNAYSPSLRRLAFLAAHQLS 191

Query: 181 F---PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAI 237
                L EG +    GP +ET AE R+++  G DVVGMS +PEV++AR   LKV+ +S +
Sbjct: 192 LDRSALAEGTYAWVSGPTYETPAEGRLLRNAGADVVGMSTIPEVLAAREAGLKVMVLSLV 251

Query: 238 TNMAEGLSD----------------------VKLSHAQTLAAAELSKQNFINLICGFLRK 275
           TN     ++                        +SH + L   +      + L+   +  
Sbjct: 252 TNFVVIPNEYRSLREEVEAELSGKPIEIPVVQTVSHEEVLLIGKEKATVMMKLVEKVVEL 311

Query: 276 I 276
           +
Sbjct: 312 L 312


>UniRef50_A9A3N5 Methylthioadenosine phosphorylase n=4 Tax=Archaea
           RepID=A9A3N5_NITMS
          Length = 263

 Score =  252 bits (643), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 50/253 (19%), Positives = 102/253 (40%), Gaps = 15/253 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
            +    G+G+   +  +E+A  +  +   G P  T       + +G  +G  +  +   G
Sbjct: 6   EIGIFGGTGIYD-SGLLEDAKEVDIDTPYGKPSDT-------ITVGTFKGRKIAFLPRHG 57

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + I  FK LG   +   +A GSL+ E+  G  V     ++      
Sbjct: 58  KKHTIPPHMINFKAN-IWAFKELGVTRIIAPSAVGSLKEELAPGHFVLPTQFLDFTKSRD 116

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIR 203
                D R      S+A+ +  E ++ + +V       + +   +V   GP F T AE +
Sbjct: 117 GSFSEDGR--VIHISVADPFCPELQSSITEVTDSLDMNIHKDCTYVCIEGPRFSTKAESK 174

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
             +  G D++GM++VPE   AR   +   ++S +T+     ++  ++  + L     + +
Sbjct: 175 FYRTTGADIIGMTLVPECQLAREAQICYASISTVTDYDVW-AEKPVTAKEVLETLSKNVE 233

Query: 264 NFINLICGFLRKI 276
               ++   + KI
Sbjct: 234 GTKKILTELIEKI 246


>UniRef50_B3T2V4 Putative phosphorylase family 2 n=2 Tax=environmental samples
           RepID=B3T2V4_9ARCH
          Length = 268

 Score =  251 bits (641), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 54/255 (21%), Positives = 107/255 (41%), Gaps = 15/255 (5%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           T  +    G+G+   ++ ++++  I+ E   G    T       + +G  +G  +  M  
Sbjct: 5   TAEIGIFGGTGIYD-SELLQDSKEITIETPYGKTSDT-------ITIGEFKGKKIAFMPR 56

Query: 85  RG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            G  H      +    + +  FK LG   +   +A GSL+ E+  G+ V     I+    
Sbjct: 57  HGKKHSIPPHMINYCAN-VWAFKELGITRIVSPSAVGSLKEEIKPGNFVLPTQFIDFTKS 115

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAE 201
                  D R      S+A+ +  E + ++ + A  +G  L +   +    GP F T AE
Sbjct: 116 RKNSFSEDGR--VIHISVADPFCPELQEIVSETANNQGITLHKDCTYACIEGPRFSTKAE 173

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELS 261
            R  +  G D++GM++VPE   AR   +  V++S +T+     ++  ++  + +     +
Sbjct: 174 SRFYKSTGSDIIGMTLVPECQLAREAQICYVSISTVTDYDVW-AEKPVTAKEVMDTLSKN 232

Query: 262 KQNFINLICGFLRKI 276
            Q    L+   + K+
Sbjct: 233 VQTTKKLLAELIHKM 247


>UniRef50_B8ICG2 Purine nucleotide phosphorylase n=28 Tax=Alphaproteobacteria
           RepID=B8ICG2_METNO
          Length = 286

 Score =  250 bits (639), Expect = 4e-65,   Method: Composition-based stats.
 Identities = 102/247 (41%), Positives = 135/247 (54%), Gaps = 3/247 (1%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +A + G+GLG LA +IE    + Y ++P FPVS V GHAG+LV G L G PV+  +GR H
Sbjct: 36  LAVVAGTGLGPLAARIEAPRILPYAEIPHFPVSGVSGHAGQLVAGDLGGRPVLLFQGRAH 95

Query: 88  FYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG 147
            YE      M   +     LG   L  TNAAGSLR E G G L  + DH+N     P++G
Sbjct: 96  AYEQGDAAAMRVPLGVLAALGAPPLLLTNAAGSLRHEAGPGRLALITDHLNLSGLNPLIG 155

Query: 148 LNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQI 207
            + +    RF  + +AYD   R  L   A      L EGV+  + GP+FET AEIRM   
Sbjct: 156 EHSEA---RFVPMVDAYDPGLRKSLHGAAAAADLVLHEGVYAWFLGPSFETPAEIRMAGR 212

Query: 208 IGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFIN 267
           +G D+VGMS VPEVI AR   L+V A+S +TN A G       HA+T   A  + ++   
Sbjct: 213 LGADLVGMSTVPEVILARFFGLRVAALSIVTNYAAGFDGGAPHHAETKRVAAAAAEDVGR 272

Query: 268 LICGFLR 274
           L+  +L 
Sbjct: 273 LLAVWLA 279


>UniRef50_Q0W2D2 Putative purine phosphorylase (Family 2) n=1 Tax=uncultured
           methanogenic archaeon RC-I RepID=Q0W2D2_UNCMA
          Length = 258

 Score =  244 bits (623), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 67/253 (26%), Positives = 106/253 (41%), Gaps = 14/253 (5%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           PR A I GSG   +         +         V T +G A      + +G   V +   
Sbjct: 2   PRTAIIGGSGFYCVPGCNLKEKKV---------VRTKYGDATLFFYENEKGAEFVFLPRH 52

Query: 86  G--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           G  H      +    + I   K  G E +   ++ GSLR  +  G  V L   ++     
Sbjct: 53  GEGHTCAPHRINYRANVI-ALKEAGIERIIGISSVGSLREAIRPGDFVLLDQFLDFTKAR 111

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIR 203
           P+   ++D        +   Y  + R  +    + +     +G +V   GP FETAAEIR
Sbjct: 112 PITFFDEDGC-VVHTDMTEPYCHDLRQCILSAPRGDIRLHDKGTYVCTEGPRFETAAEIR 170

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
           M   +GGDVVGM+ VPEV+ AR   +    +S  TN A G+S V ++H + L A +  + 
Sbjct: 171 MYATLGGDVVGMTGVPEVVLARELGMCYAGISVATNYAAGISKV-VTHEEVLEAMKKIET 229

Query: 264 NFINLICGFLRKI 276
              + + G +  +
Sbjct: 230 VLASYVVGCITTV 242


>UniRef50_UPI000038E4F5 5''''-methylthioadenosine phosphorylase II n=1 Tax=Ferroplasma
           acidarmanus fer1 RepID=UPI000038E4F5
          Length = 257

 Score =  244 bits (623), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 53/252 (21%), Positives = 104/252 (41%), Gaps = 18/252 (7%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           V  I GSGL ++   +E    +  +   G P       +  L +G + GV V  +   G 
Sbjct: 4   VGIIGGSGLYSI---METRKTMDIDTPYGKP-------SAPLEIGEINGVEVAFLPRHGK 53

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H      +    + I   +  G + +   NA GSL+ E   G +V     I+      +
Sbjct: 54  KHTIPPHMVNYKAN-IFALQKAGVQRIIGLNAVGSLKEEYKPGDIVIPDQFIDFTKRRDL 112

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRM 204
              N         S+A+ + ++  A   +  K+  FP+ + G ++   GP F T AE +M
Sbjct: 113 TYYNGPD--VYHISMADPFCSDISAKAYEAGKKLSFPVHKNGAYICIEGPRFSTRAESKM 170

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
            +    D++GM++VPE+  A    +    ++ +T+      D  +  +  +   + S++ 
Sbjct: 171 FRNF-ADIIGMTLVPEINLAAELSMCYGMLATVTDYDAWK-DEAVEASDVMQIMKESEEK 228

Query: 265 FINLICGFLRKI 276
              ++   + +I
Sbjct: 229 VSKMLYNLVPEI 240


>UniRef50_Q3ZZT2 Methylthioadenosine phosphorylase n=7 Tax=cellular organisms
           RepID=Q3ZZT2_DEHSC
          Length = 294

 Score =  241 bits (615), Expect = 2e-62,   Method: Composition-based stats.
 Identities = 56/255 (21%), Positives = 104/255 (40%), Gaps = 15/255 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I G+GL  + + + +    + +   G P       +  +V G+L GV V  +   G
Sbjct: 6   KIGVIGGTGLYDI-EGLTDIREHTLDTPFGKP-------SDIIVTGNLNGVGVAFLPRHG 57

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + I   K LG E +   N+ GS + EV  G L+     I+      
Sbjct: 58  RGHRILPSEIPSRAN-IYALKSLGVEHIIAVNSVGSFKKEVKPGHLLIPDQLIDRTSQRT 116

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIR 203
                  +      + +  +    R LL + AKE G  +   G +V   GP F T AE R
Sbjct: 117 NTFF--GKGIVAHIAFSQPFCPNLRKLLFECAKEAGANVHNGGTYVVMEGPAFSTQAESR 174

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQTLAAAELSK 262
           + +  G DV+GM+ +PE   AR  ++    ++  T+      + + ++  + +A    + 
Sbjct: 175 LHKSWGADVIGMTALPEAKLAREAEICYAIIACATDYDAWHEEEEAVTVDKVIATLRGNI 234

Query: 263 QNFINLICGFLRKIA 277
                +I   + +I+
Sbjct: 235 NLSKEIIKLAIGRIS 249


>UniRef50_Q2CJ93 Purine nucleoside phosphorylase n=1 Tax=Oceanicola granulosus
           HTCC2516 RepID=Q2CJ93_9RHOB
          Length = 276

 Score =  240 bits (613), Expect = 3e-62,   Method: Composition-based stats.
 Identities = 96/277 (34%), Positives = 143/277 (51%), Gaps = 11/277 (3%)

Query: 5   QFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHG 64
             +      +  I+    D  P +A  LGSGLG LAD + +   I Y  +P FPVSTV G
Sbjct: 1   MLNAKLSDAVAAIRAR-TDMVPEIALTLGSGLGPLADHL-DGTTIPYADIPHFPVSTVQG 58

Query: 65  HAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPE 124
           H G L++G L G   V M+GR H YEG     +   +R    LG +    TNAAG +   
Sbjct: 59  HDGVLMVGTLFGRACVAMRGRVHMYEGYSAQEVAFPMRVMAALGAQTAIFTNAAGGMGEG 118

Query: 125 VGAGSLVALKDHINTM---PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF 181
           +  G LVA++DH++        P+ G ND   GERF S+  AYD E   L+    +    
Sbjct: 119 MQVGDLVAIEDHLSLAVASGHDPLRGPNDPGIGERFVSMNRAYDPELIDLV----QSLSP 174

Query: 182 PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA 241
            +  GV+    GP+FE  A IR++++ G D+ GMS VPEVI+ARH  ++V+A+SA+TN+A
Sbjct: 175 DIARGVYGHLVGPSFEPPALIRLLKLAGVDLAGMSTVPEVIAARHMGVRVLALSAVTNIA 234

Query: 242 EGL--SDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
                     + A+   +  + +   + L+   +  +
Sbjct: 235 VSSTADSHVTNEAEVWESIRIIEPKLLALMQALIPGL 271


>UniRef50_Q0BRD3 5'-methylthioadenosine phosphorylase n=113 Tax=cellular organisms
           RepID=Q0BRD3_GRABC
          Length = 319

 Score =  239 bits (610), Expect = 8e-62,   Method: Composition-based stats.
 Identities = 56/258 (21%), Positives = 98/258 (37%), Gaps = 15/258 (5%)

Query: 23  DFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM 82
              P +  I GSGL  + D +EN      E   G P       + +L+ G L GV  V +
Sbjct: 28  RIQPVIGIIGGSGLYDI-DGLENKEWRRVETPWGLP-------SDDLLFGTLDGVQCVFL 79

Query: 83  KGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
              G  H      +    + I   K  GC  +   +A GSL+ ++  G  V +   I+  
Sbjct: 80  PRHGRGHRLSPSHLNYRAN-IDAMKRAGCTDILSLSAVGSLKKKLPPGHFVIVDQFIDRS 138

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETA 199
                    D        S+A+        ++++ AK    P    G ++   GP F T 
Sbjct: 139 FAREKSFFGDGC--VAHVSVADPVCPRIGDVVEQAAKRLSLPYARGGTYLVMEGPQFSTR 196

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDV-KLSHAQTLAAA 258
           AE  + +  G  V+GM+ +PE   AR  ++    V+ +T+      D   ++    +   
Sbjct: 197 AESELYRSWGCSVIGMTNMPEAKLAREAEMCYATVAMVTDYDCWHEDHDHVTVDAVIRVL 256

Query: 259 ELSKQNFINLICGFLRKI 276
             + +    L+   +  +
Sbjct: 257 RGNAEKARALVQAVVPVL 274


>UniRef50_O27633 Methylthioadenosine phosphorylase n=7 Tax=Archaea
           RepID=O27633_METTH
          Length = 280

 Score =  239 bits (609), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 59/218 (27%), Positives = 95/218 (43%), Gaps = 10/218 (4%)

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGR--GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAA 118
           T +G   E+ +  L G  V  +     GH      +    + I   K LG   +  TNA 
Sbjct: 27  TPYGKTPEISVFKLHGRRVAFIPRHSPGHDKPPHMVNYRAN-IWALKELGVRQIIATNAV 85

Query: 119 GSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE 178
           GSL+  +G G  V   D ++     P    ++         +   Y    R+ L      
Sbjct: 86  GSLKRSIGPGDFVVPHDFLDFTRSRPSTFYDEKTV---HVDMTEPYCRNIRSAL----SG 138

Query: 179 EGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
               +  GV+V   GP FET AEIRM Q +GG VVGM+ +PE + AR  ++   ++  ++
Sbjct: 139 SSGVVDGGVYVCTEGPRFETPAEIRMFQTLGGTVVGMTGLPEAVLARELEMCYASICLVS 198

Query: 239 NMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           N A  +S  KL+  +     +  K + I++I   +R +
Sbjct: 199 NYAASISPSKLTIDEVFEIMDEKKNDLIDIIDAAIRDL 236


>UniRef50_P46862 Purine nucleoside phosphorylase n=79 Tax=Actinomycetales
           RepID=PUNA_MYCLE
          Length = 268

 Score =  239 bits (609), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 91/270 (33%), Positives = 136/270 (50%), Gaps = 12/270 (4%)

Query: 7   SHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQI-ENAVAISYEKLPGFPVSTVHGH 65
                    +I          VA +LGSG  +    +  +       +LPGF      GH
Sbjct: 9   DELARRAAQVIGERTGILKHDVAVVLGSGWSSAVAALGSSRAVFPQAELPGFITPNAAGH 68

Query: 66  AGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
            GEL+   +    V+ + GR H YEG  +  +   +RT    G  ++  TNAAG LR ++
Sbjct: 69  TGELLSVRIGAHRVLVLAGRIHPYEGHDLRHVVHPVRTACAAGARIIVLTNAAGGLRADM 128

Query: 126 GAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE 185
             G LV + DH+N    +P+VG +       F  L NAY    R L    A +    LTE
Sbjct: 129 AVGQLVLISDHLNLTTRSPLVGTH-------FVDLTNAYTTRLRKL----ASDTDPTLTE 177

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           GV+ + PGP++ET AEIRM++++G D+VGMS V E I+AR    +V+ VS +TN+A G++
Sbjct: 178 GVYAAQPGPHYETPAEIRMLRMLGADLVGMSTVHETIAARAAGAEVLGVSLVTNLAAGIT 237

Query: 246 DVKLSHAQTLAAAELSKQNFINLICGFLRK 275
              L+HA+ LAA   S     +L+   + +
Sbjct: 238 GKPLNHAEVLAAGTASANRIGSLLADIIAR 267


>UniRef50_C0QPX3 Methylthioadenosine phosphorylase n=6 Tax=Aquificales
           RepID=C0QPX3_PERMH
          Length = 280

 Score =  238 bits (608), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 57/271 (21%), Positives = 110/271 (40%), Gaps = 31/271 (11%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +  I GSGL  + D I     ++     G P       +   ++   +G   V +   G 
Sbjct: 2   LGVIGGSGLYQV-DDINILDEVNISTPYGEP-------SDRYIIAEYRGKKAVFLPRHGK 53

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H Y    +    + I  F+ LG + +   +A G + P +  G  V     I+     P+
Sbjct: 54  GHKYPPHLINYRAN-IWGFRKLGVDRILSVSAVGGINPLLKPGDFVLSDQFIDFTKVRPV 112

Query: 146 VGLND-------------------DRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE- 185
                                            + + + +  R  L  +  E+G+   + 
Sbjct: 113 TFYEGVYTIYDETDGKDDLVSEYLKNNRVVHIDVTDPFCSSMRKTLSDILDEKGYRYHKK 172

Query: 186 GVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
           G +++  GP  ET+AEI+   I+G D+VGM++VPE++ AR   +   +++ +TN+A G+S
Sbjct: 173 GTYIATEGPRLETSAEIKAFSILGADIVGMTLVPEIVLARELSMHFASINVVTNLAAGIS 232

Query: 246 DVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
             +L+  + +   +        +I  F+ K+
Sbjct: 233 GERLTSDEVIQMMKEKNDQIKEIILSFIEKV 263


>UniRef50_A4U101 Purine phosphorylase, family 2 n=4 Tax=Proteobacteria
           RepID=A4U101_9PROT
          Length = 291

 Score =  238 bits (607), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 53/256 (20%), Positives = 100/256 (39%), Gaps = 15/256 (5%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
            P +  I GSG+  + D + N      +   G P       + +L+ G L G  +V +  
Sbjct: 3   KPVLGIIGGSGVYDI-DGLTNTQWRRVDSPFGQP-------SDDLLFGELNGQQLVFLPR 54

Query: 85  RG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            G  H      +    + I   K  G   +   +A GSL+ E+  G+ V +   I+    
Sbjct: 55  HGRGHRIPPSELNYRAN-IDALKRAGVTEIVSVSAVGSLKEELPPGTFVIVDQFIDRTFA 113

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF-PLTEGVFVSYPGPNFETAAE 201
                           S+A+        ++++ AK+ G   +  G ++   GP F T AE
Sbjct: 114 RTKSFFETGL--VAHVSMAHPVCGRLGDIIEQAAKDAGIVAVRGGTYLVMEGPQFSTQAE 171

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQTLAAAEL 260
             + +  G DV+GM+ +PE   AR  ++    V+ +T+      D   ++  Q +     
Sbjct: 172 SNLYRQWGCDVIGMTNMPEAKLAREAEMCYATVAMVTDYDCWHPDHDAVTVEQVVKVLLE 231

Query: 261 SKQNFINLICGFLRKI 276
           +      L+   + ++
Sbjct: 232 NADRARALVKAIVPQV 247


>UniRef50_B1I2E1 Methylthioadenosine phosphorylase n=33 Tax=cellular organisms
           RepID=B1I2E1_DESAP
          Length = 292

 Score =  238 bits (607), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 68/253 (26%), Positives = 107/253 (42%), Gaps = 14/253 (5%)

Query: 24  FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
            T R+A I G+G+   A            ++    V T +G    L +G  +G  V  M 
Sbjct: 1   MTVRIAVIGGTGVYDPA---------MLGEIREDHVRTPYGEVD-LQVGRFEGREVAFMA 50

Query: 84  GRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMP 141
             G  H      +    + I   K LG   +  T A GSL  ++  G  V     ++   
Sbjct: 51  RHGRWHSVPPHLVNYRAN-IMALKQLGVRSILATAAVGSLNLDMKPGDFVFCDQFLDFTK 109

Query: 142 GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAA 200
                       G     +   Y  E RALL++ A      +   G + +  GP FE+ A
Sbjct: 110 SRAQTFFEGGPEGVVHVDMTEPYCPELRALLEEAAAALKLTVHPGGTYAATEGPRFESPA 169

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAEL 260
           EIRM++ +G D+ GM+ VPEV+ AR   +    +  +TN A G+S  +L+H + L A  +
Sbjct: 170 EIRMLRHLGADLAGMTGVPEVVLAREAGICYATICMVTNFAAGISPHRLTHEEVLEAMRV 229

Query: 261 SKQNFINLICGFL 273
           +     +LI G +
Sbjct: 230 NAAKIRSLIAGTV 242


>UniRef50_B9KZC3 Methylthioadenosine phosphorylase n=2 Tax=Bacteria
           RepID=B9KZC3_THERP
          Length = 289

 Score =  237 bits (606), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 55/254 (21%), Positives = 99/254 (38%), Gaps = 14/254 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
            +  I GSGL  + + + +   I+ E   G P  T       + LG L G+ V  +   G
Sbjct: 4   ELGVIGGSGLYRMPE-LTDVEEIAIETPFGRPSDT-------ITLGTLHGMRVAFIPRHG 55

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H +    +    +     K LG + +   +A GSLR E+     V     ++     P
Sbjct: 56  RAHQHSPSNVPARAN-FWALKSLGVQWVVSVSAVGSLREEIAPLDFVVPDQVVDRTVRRP 114

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIR 203
               ++        +L   +  E R  L + A   G  +   G ++   GP F T AE  
Sbjct: 115 RSFFDESGL-VVHVTLDEPFCPELRWALTQAAIAAGVRVHDRGTYICIEGPQFSTRAESN 173

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL-SDVKLSHAQTLAAAELSK 262
           + +  G D++GM+ +PEV  AR  +L    ++ +T+       +  +S +  L     + 
Sbjct: 174 LYRSWGLDIIGMTAMPEVRLAREAELCFALLALVTDYDVWHAEEEPVSVSVVLERLHQNV 233

Query: 263 QNFINLICGFLRKI 276
           Q     +   +  +
Sbjct: 234 QAAQRALSALIEYL 247


>UniRef50_A3EWJ6 Methylthioadenosine phosphorylase n=2 Tax=Leptospirillum sp. Group
           II RepID=A3EWJ6_9BACT
          Length = 300

 Score =  236 bits (603), Expect = 5e-61,   Method: Composition-based stats.
 Identities = 56/266 (21%), Positives = 99/266 (37%), Gaps = 18/266 (6%)

Query: 18  KTYKPDFTP---RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL 74
           +T + +  P    V  I GSGL  + + +        E   G         +   ++G +
Sbjct: 5   RTKRGEGNPGSGPVGIIGGSGLYQM-EGLTIEEERVVETPWGVS-------SDPYLIGKV 56

Query: 75  QGVPVVCMKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
             +PVV +   G  H Y    +    + +   K LG   +   +A GSL+ E+  G +V 
Sbjct: 57  GTLPVVFLSRHGKGHRYLPSEINYRAN-LAGLKSLGVSRVLSVSAVGSLKEEIAPGDMVL 115

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSY 191
           + D I+     PM    +   G           ++         +  G P   G  ++  
Sbjct: 116 VDDFIDLTRQRPMSFYGNGAVG--HTPYGRPVCSDLFEAFSGACEHLGLPTHRGGTYICM 173

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LS 250
            GP F T AE R+ +  G DV+GM+   E   AR   L    ++  T+      D   ++
Sbjct: 174 EGPAFSTRAESRLYRQWGADVIGMTNGTEARLAREIGLCYATLALATDYDCWHPDHDMVT 233

Query: 251 HAQTLAAAELSKQNFINLICGFLRKI 276
            A  +     + +    ++   L +I
Sbjct: 234 VADVIRIMNQNVRRANTILLDALERI 259


>UniRef50_Q83H43 Purine nucleoside phosphorylase n=3 Tax=Tropheryma whipplei
           RepID=Q83H43_TROWT
          Length = 294

 Score =  236 bits (603), Expect = 6e-61,   Method: Composition-based stats.
 Identities = 84/270 (31%), Positives = 131/270 (48%), Gaps = 13/270 (4%)

Query: 9   NPLFCIDIIKTYKPDFTPRVAFILGSGL-GALADQIENAVAISYEKLPGFPVSTVHGHAG 67
                   I          +A  LGSG   A+++  E    I  + + GF    + GH+G
Sbjct: 28  AATLAAKQIADITGIARHDIAVTLGSGWVDAVSNLGELITTIPAQDIHGFFPPVLAGHSG 87

Query: 68  ELVLGHL-QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVG 126
            L    L  GV V+ +  R H Y+G G   +   I+T    G  +   TN AGS  P+ G
Sbjct: 88  VLTSIRLTCGVYVLVIGARTHLYQGHGPEAVVHGIKTAHAAGARVAILTNGAGSTVPDWG 147

Query: 127 AGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG 186
            G +V +KDHIN    +P+ G N       F  +++ Y A  R  + ++A      + +G
Sbjct: 148 PGEVVVIKDHINLTGKSPLSGAN-------FCDMSDIYTAALRQKILQMAPN----IPQG 196

Query: 187 VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD 246
           V+   PGP +ET AE++M++ IG D+VGMS   E I A+   + VV +S +TN+A G+  
Sbjct: 197 VYAQMPGPQYETPAEVKMLRTIGADLVGMSTALEAIMAKSLKMNVVGLSLVTNLAAGIGT 256

Query: 247 VKLSHAQTLAAAELSKQNFINLICGFLRKI 276
            +LSH + L  +E ++Q     +   +R I
Sbjct: 257 GQLSHDEVLTVSEQARQKTSAFLVELIRDI 286


>UniRef50_A2FHY6 Inosine guanosine and xanthosine phosphorylase family protein n=1
           Tax=Trichomonas vaginalis RepID=A2FHY6_TRIVA
          Length = 780

 Score =  235 bits (599), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 79/267 (29%), Positives = 128/267 (47%), Gaps = 8/267 (2%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
            I  +K+     TP V  +LGSGLG+   ++   + I Y+ +PG   +TV GH+G L+ G
Sbjct: 13  AIKFVKSQITG-TPEVGVVLGSGLGSYGQELAEPITIPYKNIPGMLDTTVPGHSGCLIFG 71

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            +  V V+C+ GR H YEG     +  AIR     GC L+  TNAAG+    +  G L  
Sbjct: 72  KIGEVKVLCLSGRSHQYEGLHPHEIQFAIRLLGGCGCRLVILTNAAGTCDELLEVGDLAP 131

Query: 133 LKDHINTMPGTPMVGLNDDRFGE---RFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFV 189
           + DH+N        G  ++               YD E + ++  VA E         + 
Sbjct: 132 MLDHLNFT----HRGYTEEPLEIKDFYHLIQNGMYDKEAQQVIHDVAVESNLSTRGCNYT 187

Query: 190 SYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKL 249
              GP +E  AE+   + +G    GMS V EVI+A+   + ++A+S +TN A G++   L
Sbjct: 188 YNMGPTYEAHAEVWGQKKLGCTNFGMSTVAEVIAAKEIGVPILAMSFVTNKAAGITGKLL 247

Query: 250 SHAQTLAAAELSKQNFINLICGFLRKI 276
           +H +   AA+  ++    L+   + ++
Sbjct: 248 THVEVAEAAKKGEEGMKKLVSTTIMRL 274



 Score = 59.9 bits (144), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 54/259 (20%), Positives = 90/259 (34%), Gaps = 47/259 (18%)

Query: 22  PDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVC 81
            +     A +L +G  ++   +E  V +S   LP FP   +     ++ +G L G  V  
Sbjct: 316 GETKIDTAIVL-AGTHSVP--VEAKVTVSVLDLPKFPA--LQHTRAQIKIGTLAGKNVAV 370

Query: 82  MKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMP 141
           + G  + Y G         +  F  LG +    T A GS   +     +  +KD I    
Sbjct: 371 VDG-IYDYCGFDHYATYYLVNLFAKLGAKEYIQTFATGSFGEQ----GVKYIKDVIPL-F 424

Query: 142 GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYP--GPNFETA 199
             P+V             +                        EG  +  P  GP F T 
Sbjct: 425 ERPIVVP----RAMPHQGM------------------------EGTAIVAPYHGPEFWTP 456

Query: 200 AEIRMMQIIGGD--VVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAA 257
           AE + M +IG     +G++V  E+ +A    +KVV +  I    +       +  Q + A
Sbjct: 457 AEGKAMTVIGATHATLGLTVGLEIAAA--LKMKVVGI--IDGAFDAHLLEGTTIEQIVKA 512

Query: 258 AELSKQNFINLICGFLRKI 276
              +      L+   L K+
Sbjct: 513 TTAAAPEVAKLVEESLAKV 531


>UniRef50_D2RKT9 Purine or other phosphorylase family 1 n=1 Tax=Acidaminococcus
           fermentans DSM 20731 RepID=D2RKT9_ACIFE
          Length = 275

 Score =  234 bits (597), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 63/252 (25%), Positives = 101/252 (40%), Gaps = 14/252 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I G+G+   +         ++ KL    V T  G A  L  G   G  +  +   G
Sbjct: 3   KIGIIGGTGVEDAS---------AFGKLAPLTVETPFGQARCL-KGTAAGHEIYFLARHG 52

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + I   K LG   +    A GSL   +  G+ V     ++      
Sbjct: 53  LDHSVPPHKINYRAN-IFALKKLGVTEILSFTAVGSLNRGLPPGTFVVTSQLLDFTKSRV 111

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAEIR 203
               N +         A  Y    R  L +   + G     +G +V   GP +ETAAE+R
Sbjct: 112 NTFFNGENGQVAHVDFAQPYCPALRERLNRCLVKLGLRHSKQGTYVVTEGPRYETAAEVR 171

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
           M   +GGDV GM+ +PE + AR  ++     S +TNM  GL+   LSH +   A E  ++
Sbjct: 172 MYAAMGGDVAGMTNMPEAVLAREAEICYANCSVVTNMGSGLAVRSLSHEEVTEAMERLEK 231

Query: 264 NFINLICGFLRK 275
             + +I  ++  
Sbjct: 232 QILAVIEAYVND 243


>UniRef50_B0K2V3 Purine phosphorylase, family 2 n=10 Tax=Thermoanaerobacteraceae
           RepID=B0K2V3_THEPX
          Length = 256

 Score =  234 bits (597), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 67/251 (26%), Positives = 112/251 (44%), Gaps = 18/251 (7%)

Query: 29  AFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG-- 86
           A I G+G   +  ++   +           V T +G   E+ +  ++G  +  +   G  
Sbjct: 4   AIIGGTGFYEIGQKVSKKL-----------VETKYGEV-EIDIVTIEGEKIGFLPRHGKG 51

Query: 87  HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
           H      +    + I   K +G + ++ T A GS       G +V LKD ++     P+ 
Sbjct: 52  HAVPPHLVNYRAN-IMALKQMGVKYVYATAAVGSFNENYEPGDVVVLKDFLDFTKSRPLT 110

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIRMM 205
               +    R   +++ Y +  RA     AK+E   +  + V+V   GP FETA EIRM 
Sbjct: 111 FFEGEDGVVRHVDMSDPYCSNLRAKFYNAAKKEDLLIKGDAVYVCTEGPRFETAQEIRMY 170

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNF 265
           + +G DVVGM+ VPEVI A+   +   AV  ++N A G+    ++  +     EL+K+  
Sbjct: 171 KNLGADVVGMTNVPEVILAKELGMCYAAVGIVSNWATGMKGS-ITLHEIKDTLELNKEKV 229

Query: 266 IN-LICGFLRK 275
           I   I  FL +
Sbjct: 230 IKTFIRVFLEE 240


>UniRef50_D1BYW2 Purine nucleotide phosphorylase n=6 Tax=Actinomycetales
           RepID=D1BYW2_XYLCX
          Length = 283

 Score =  234 bits (597), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 86/279 (30%), Positives = 130/279 (46%), Gaps = 17/279 (6%)

Query: 2   SQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAV-AISYEKLPGFPVS 60
                        D I          +A +LGSG G  A+ + + V  I   ++PGF   
Sbjct: 14  PATDPFDVARAAADHIAEVSGVDGHDIALVLGSGWGGAAELLGDVVAEIPSHEIPGFAKP 73

Query: 61  TVHGHAGELVLGHLQ-----GVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCT 115
           TV GH G      ++        V+ +  R H YEGRG+  +  A+RT    G   L  T
Sbjct: 74  TVAGHVGTTRSVCIERADGSTRNVLVLGSRTHLYEGRGVRRVAHAVRTAAATGASALVLT 133

Query: 116 NAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKV 175
           N  G L      G +V ++DH+N    +P+        G  F  + + Y    R L + V
Sbjct: 134 NGCGGLHVSWRPGQVVLIRDHLNLTATSPL-------EGATFVDVTDLYTPRLRELARTV 186

Query: 176 AKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVS 235
                  L EGV+  +PGP++ET AE+R   I+G D+VGMS   E I+ARHC ++V+ +S
Sbjct: 187 ----DPTLPEGVYAQFPGPHYETPAEVRAAGIMGADLVGMSTGLEAIAARHCGMEVLGMS 242

Query: 236 AITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLR 274
            +TN+A G+S   LSH + L A   +     +L+   ++
Sbjct: 243 LVTNLAAGVSPQPLSHEEVLEAGAKAGPVISDLLARIVK 281


>UniRef50_A9BDU8 5'-methylthioadenosine phosphorylase n=13 Tax=Cyanobacteria
           RepID=A9BDU8_PROM4
          Length = 316

 Score =  233 bits (595), Expect = 4e-60,   Method: Composition-based stats.
 Identities = 55/258 (21%), Positives = 109/258 (42%), Gaps = 18/258 (6%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           R+  + GSGL ++ + +EN   I  +   G P       + +L LG L G+ VV +   G
Sbjct: 24  RLGVLGGSGLYSI-NNLENIKEIEIDTPYGKP-------SDKLRLGILGGMEVVFLARHG 75

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H +   G+    + I   + LG   +   +A GSL+ +V    +V     I+     P
Sbjct: 76  RHHTFTPTGIPYRAN-IWALRSLGVRWILAPSAVGSLQEQVRPLDMVVPDQFIDRTHQRP 134

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE---GFPLTEG-VFVSYPGPNFETAA 200
           +   +D        ++A+ +      LL +  ++    G  L  G ++++  GP F T A
Sbjct: 135 LTFFSDG--AVAHVTMADPFCPTLSRLLTEEGQKLMPEGRQLHRGGIYLAMEGPAFSTRA 192

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VKLSHAQTLAAAE 259
           E ++ +  G  V+GM+   E   AR  ++   ++S +++          +S    +   +
Sbjct: 193 ESQLYRSWGCTVIGMTNHTEARLAREAEIAYASISMVSDYDCWHEGYGNVSVDMVIENLQ 252

Query: 260 LSKQNFINLICGFLRKIA 277
            +      ++    +K+A
Sbjct: 253 TNASVANKIVEATAKKVA 270


>UniRef50_Q1K0Y4 Inosine guanosine and xanthosine phosphorylase n=1
           Tax=Desulfuromonas acetoxidans DSM 684
           RepID=Q1K0Y4_DESAC
          Length = 274

 Score =  232 bits (593), Expect = 8e-60,   Method: Composition-based stats.
 Identities = 81/241 (33%), Positives = 128/241 (53%), Gaps = 7/241 (2%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLP---GFPVSTVHGHAGELVLGHLQGVPVVCMK 83
             A ILGSG  + A+ +    ++ Y ++       ++ V GHAG+L +       ++  +
Sbjct: 22  ETAIILGSGWSSWAENLVIECSLDYSEVFRTQENSIANVPGHAGKLHVATWGECRLLVFQ 81

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           GR H Y+G     ++   +    +G + L  TNA G + PE+ AGS V +KDH+N     
Sbjct: 82  GRFHLYQGLTAAQVSQTAQLAHAMGTQRLVLTNAVGGIAPELMAGSFVIIKDHLNFQGDN 141

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIR 203
           P+ GL+       F  L N Y  ++   L+  A ++G  L  GV  +  GP++ET AEIR
Sbjct: 142 PLRGLSPS----PFIDLCNLYCTDFYPDLKIWADQQGIALHRGVLAAVVGPSYETPAEIR 197

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
            ++ +G DVV MS+VPE I AR+  L+VV +S +TN A GLS   L H + L   + ++ 
Sbjct: 198 ALERLGADVVSMSMVPEAIMARYLGLEVVGLSLVTNPAAGLSTDPLQHQEVLQCGQDAQA 257

Query: 264 N 264
           +
Sbjct: 258 H 258


>UniRef50_P81989 Purine nucleoside phosphorylase n=7 Tax=Actinobacteria (class)
           RepID=PUNA_CELSP
          Length = 282

 Score =  231 bits (589), Expect = 3e-59,   Method: Composition-based stats.
 Identities = 90/272 (33%), Positives = 130/272 (47%), Gaps = 17/272 (6%)

Query: 10  PLFCIDIIKTYKPDFTPRVAFILGSGLGALADQI-ENAVAISYEKLPGFPVSTVHGHAGE 68
                D I          +A +LGSG G  A+ + E    +   ++PGF    V GH   
Sbjct: 22  ARAAADHIAQATGVEGHDMALVLGSGWGGAAELLGEVVAEVPTHEIPGFSAPAVAGHLSV 81

Query: 69  LVLGHLQG-----VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRP 123
                ++         + +  R H YEG+G+  +   +RT    G E L  TN  G L  
Sbjct: 82  TRSIRVERADGSVRHALVLGSRTHLYEGKGVRAVVHGVRTAAATGAETLILTNGCGGLNQ 141

Query: 124 EVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL 183
           E GAG+ V L DHIN    +P+ G         F  L + Y    R L  +V       L
Sbjct: 142 EWGAGTPVLLSDHINLTARSPLEGP-------TFVDLTDVYSPRLRELAHRV----DPTL 190

Query: 184 TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG 243
            EGV+  +PGP++ET AE+RM  I+G D+VGMS   E I+ARHC L+V+ VS +TN+A G
Sbjct: 191 PEGVYAQFPGPHYETPAEVRMAGILGADLVGMSTTLEAIAARHCGLEVLGVSLVTNLAAG 250

Query: 244 LSDVKLSHAQTLAAAELSKQNFINLICGFLRK 275
           +S   LSHA+ + A + +      L+    ++
Sbjct: 251 ISPTPLSHAEVIEAGQAAGPRISALLADIAKR 282


>UniRef50_C6HVW5 Methylthioadenosine phosphorylase n=1 Tax=Leptospirillum
           ferrodiazotrophum RepID=C6HVW5_9BACT
          Length = 307

 Score =  230 bits (588), Expect = 3e-59,   Method: Composition-based stats.
 Identities = 61/263 (23%), Positives = 101/263 (38%), Gaps = 15/263 (5%)

Query: 18  KTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGV 77
           +  K +    +  I GSGL  L   + + V    E   G P       +   + G L GV
Sbjct: 5   RKRKSEEMAPIGVIGGSGLYQL-KGLSDLVPTVVETPWGQP-------SDPYMTGSLGGV 56

Query: 78  PVVCMKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKD 135
           PVV +   G  H Y    +    + I  F  LG + +   +A GSLR ++  G +V +  
Sbjct: 57  PVVFLSRHGSGHRYLPGEVNYRAN-IAGFVALGVKRILSVSAVGSLREDIVPGDMVVIDQ 115

Query: 136 HINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGP 194
            I+   G P         G    + A+    +    L    +  G     +G +    GP
Sbjct: 116 FIDGTRGRPSTFYGQGAVG--HTAFAHPICPDLAQTLIGACRTAGVRHHVKGTYYCMEGP 173

Query: 195 NFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQ 253
            F T AE  + +  G  V+GM+ V E   AR   L    ++  T+      D   ++ ++
Sbjct: 174 AFSTQAESFLYRQFGAHVIGMTNVTEARLAREAGLCYATLALSTDFDCWHPDHDAVTVSE 233

Query: 254 TLAAAELSKQNFINLICGFLRKI 276
            LA    + +N   ++   L  +
Sbjct: 234 VLAVISKNVENANRILEHALSSV 256


>UniRef50_Q1NY44 Methylthioadenosine phosphorylase n=2 Tax=delta proteobacterium
           MLMS-1 RepID=Q1NY44_9DELT
          Length = 251

 Score =  230 bits (588), Expect = 3e-59,   Method: Composition-based stats.
 Identities = 68/254 (26%), Positives = 100/254 (39%), Gaps = 16/254 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +A I GSGL    +  +     + E   G P       +  L+ G L G  VV +   G 
Sbjct: 4   IAIIGGSGLDN-PEFFDVEQEFTVETPYGPP-------SAPLLQGRLDGREVVLLARHGR 55

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H      +    + +   +  GCE +  T A+GSLR E+G G LV     I+     P+
Sbjct: 56  QHTIPPSRVNNRAN-LFALREAGCERIIATAASGSLRNEIGPGHLVIPDQFIDFTRQRPL 114

Query: 146 VGLNDDRFGE---RFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAE 201
              ++   G        LA+ +D   R  +     E   PL   G  ++  GP F T AE
Sbjct: 115 TFYDEFPAGIENACHTPLADPFDETLRQKIIAAGGERQIPLHTSGTILTIEGPRFSTRAE 174

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDV-KLSHAQTLAAAEL 260
            RM Q  G D+V M+V PE I A    L    ++ +T+      D   L   Q +     
Sbjct: 175 SRMYQSWGADLVNMTVAPEAILAAELKLPYAVIAMVTDYDSWKEDEPPLLVPQLVTVFRS 234

Query: 261 SKQNFINLICGFLR 274
           + +    LI   L 
Sbjct: 235 NIEKITTLIRQTLA 248


>UniRef50_C0W9U9 Purine nucleoside phosphorylase n=1 Tax=Acidaminococcus sp. D21
           RepID=C0W9U9_9FIRM
          Length = 268

 Score =  230 bits (586), Expect = 5e-59,   Method: Composition-based stats.
 Identities = 62/252 (24%), Positives = 99/252 (39%), Gaps = 14/252 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I G+G               +  L    V T  G A E   G +    V  +   G
Sbjct: 3   KIGIIGGTG---------VEDTSIFGTLSLITVETPFGTA-EGFAGKIDDTSVYFIARHG 52

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + I   K LG   +    A GSL   +  G+ V     ++      
Sbjct: 53  KGHSLPPHRIPYRAN-IYALKKLGVTEILSFTAVGSLNRGLIPGTFVNTSQILDFTKSRE 111

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIR 203
               +           +  Y    R  L  +    G   ++ G +V+  GP +ETAAE+R
Sbjct: 112 HTFFDGGVMPVCHVDFSFPYCPVLRERLNGILTRLGVRHSKAGCYVATEGPRYETAAEVR 171

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
           M  ++GGDV GM+ +PE + AR  ++     S +TNM  GLS   LSH + +A  + + +
Sbjct: 172 MYGLMGGDVAGMTQMPEAVLAREAEICYANCSLVTNMGSGLSWTALSHEEVVAMMDENAK 231

Query: 264 NFINLICGFLRK 275
               +I  FL +
Sbjct: 232 TIARIIHAFLTE 243


>UniRef50_D1YZM1 5'-methylthioadenosine phosphorylase n=1 Tax=Methanocella
           paludicola SANAE RepID=D1YZM1_METPS
          Length = 281

 Score =  229 bits (585), Expect = 6e-59,   Method: Composition-based stats.
 Identities = 53/252 (21%), Positives = 100/252 (39%), Gaps = 14/252 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM--KG 84
           +V  I GSG+       ++          G P           ++G + G+  V +   G
Sbjct: 3   KVGIIGGSGIYD-PSMFDHVKEQKVRTPFGTP-------GDSFIVGSMNGIEAVFLSRHG 54

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           RGH Y    +    + I   K LG   +   +A GSL+  +    +V      +      
Sbjct: 55  RGHKYSPTDLNYRAN-IYGMKKLGVTHIISVSAVGSLKESLKPLDIVIPDQVYDRTTKRV 113

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
                         S A+ +  +   +L + AKE+      G ++   GP F T AE R+
Sbjct: 114 STYFEGGI--VAHISFADPFCRKLSDILYETAKEKYRVHNGGTYLCMEGPQFSTKAESRI 171

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
            + +G DV+GM+ +PE   AR  ++    ++ IT+      +  +S  Q +  A  +++ 
Sbjct: 172 YRKLGFDVIGMTALPEAKLAREAEICFAILATITDYDVWY-EEPVSIGQVIEYAAKNEEA 230

Query: 265 FINLICGFLRKI 276
             +++   + +I
Sbjct: 231 VKDILRRAVGRI 242


>UniRef50_P74469 Sll0135 protein n=67 Tax=cellular organisms RepID=P74469_SYNY3
          Length = 326

 Score =  229 bits (584), Expect = 9e-59,   Method: Composition-based stats.
 Identities = 57/269 (21%), Positives = 100/269 (37%), Gaps = 18/269 (6%)

Query: 16  IIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQ 75
            I+         +  I GSGL  + + ++N   ++ +   G P       +   ++G L 
Sbjct: 26  FIRKNSTMVNAPIGIIGGSGLYQM-EALKNVEEVTLDTPFGAP-------SDSFIVGELA 77

Query: 76  GVPVVCM--KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVAL 133
           GV V  +   GRGH      +    + I   K LG + L   +A GSL+ E     +V  
Sbjct: 78  GVRVAFLARHGRGHHLLPSEIPFRAN-IHGMKQLGVKYLISASAVGSLQAEAKPLDMVVP 136

Query: 134 KDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE---GFPLT-EGVFV 189
              I+                       N    +    L          G  L   G +V
Sbjct: 137 DQFIDRTRQRISTFF--GEGIVAHIGFGNPICPQLAQCLSTAIAGLELEGVTLHDRGTYV 194

Query: 190 SYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDV-K 248
           S  GP F T AE  + +  GG V+GM+ +PE   AR  ++    ++ +T+      D   
Sbjct: 195 SMEGPAFSTIAESNLYRSWGGTVIGMTNLPEAKLAREAEIAYATLALVTDYDCWHPDHDH 254

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRKIA 277
           ++    +   + +  N   +I   ++++A
Sbjct: 255 VTVEMVIGNLQKNAVNAQQVILETVKQLA 283


>UniRef50_C4FCF5 Putative uncharacterized protein n=2 Tax=Collinsella
           RepID=C4FCF5_9ACTN
          Length = 295

 Score =  229 bits (583), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 88/261 (33%), Positives = 132/261 (50%), Gaps = 9/261 (3%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS--TVHGHAGELVLGHLQGVP 78
           KP     +A +LGSGLG+L +++     I Y  + GFP     V GH+  +++G L GVP
Sbjct: 37  KPTMEHPIAIVLGSGLGSLGERVRVVRHIPYSDIDGFPTEAIPVEGHSFTVLVGELDGVP 96

Query: 79  VVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           VV   GR H Y+G     +T  +R    LGC  +  + A G++   +  G++  + D IN
Sbjct: 97  VVVYPGRVHMYQGYDALQVTSLVRHAHKLGCRSIVLSCATGAVGA-IAPGTVGIITDQIN 155

Query: 139 TMPGTPMVGLNDDRFG---ERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPN 195
                P+              F S+A AY      L ++ A E G  L EGV+    GP+
Sbjct: 156 LTGRNPLASPAGVAAAGLDSPFVSMAGAYSPYLSGLAREAASELGMELAEGVYAGLLGPS 215

Query: 196 FETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL 255
           +ET AEIRM+  +G D VGMS V E I AR   ++V+ ++ +TN A    +   SHA+ L
Sbjct: 216 YETPAEIRMLGTLGADYVGMSTVCEAIMARAMGMEVLGIALVTNKAGCPGE---SHAKVL 272

Query: 256 AAAELSKQNFINLICGFLRKI 276
            AA+ + +    L    +R+I
Sbjct: 273 GAADAAAEAMQALALATIRRI 293


>UniRef50_D1A6L7 Methylthioadenosine phosphorylase n=16 Tax=Actinomycetales
           RepID=D1A6L7_THECD
          Length = 279

 Score =  229 bits (583), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 54/259 (20%), Positives = 100/259 (38%), Gaps = 17/259 (6%)

Query: 22  PDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVC 81
              T  +  I GSG  +  D IE    +  +   G P       +  + +G + G  V  
Sbjct: 12  TTSTATIGVIGGSGFYSFLDDIE---EVRLDTPYGPP-------SDPIAVGTVAGRTVAF 61

Query: 82  MKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINT 139
           +   G  H Y    +    + +   + LG   +   +A GSL P+ G G+L      ++ 
Sbjct: 62  IPRHGRDHRYPPHKIPYRAN-LWALRSLGVRQVLAPSAVGSLVPQYGPGTLAVPDQLVDR 120

Query: 140 MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF-PLTEGVFVSYPGPNFET 198
             G       +   G    S A+ Y    R ++   A++  + P+  G  V   GP F T
Sbjct: 121 TYGRVQTFYEEG--GAIHVSFADPYCPVGRRVVLDTARKADWEPVDGGTLVVIEGPRFST 178

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQTLAA 257
            AE +     G  +VGM+  PE + AR   L    +  +T++  G+ + + ++  +    
Sbjct: 179 RAESQWYAAQGWTLVGMTGHPEAVLARELALCYTPICLVTDLDAGIEEGEGVTMEEVFRV 238

Query: 258 AELSKQNFINLICGFLRKI 276
              +     +L+   +  +
Sbjct: 239 FAKNVNRLRSLVTAVVEAL 257


>UniRef50_Q0F2U5 Purine nucleoside phosphorylase n=1 Tax=Mariprofundus ferrooxydans
           PV-1 RepID=Q0F2U5_9PROT
          Length = 290

 Score =  228 bits (582), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 54/250 (21%), Positives = 96/250 (38%), Gaps = 15/250 (6%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           R   I GSGL  +A  +E    ++ +   G P       + ELVL  +    VV +   G
Sbjct: 8   RTGIIGGSGLYNIA-GVEIIDTLTIDTPYGAP-------SDELVLARIGDQEVVFLPRHG 59

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + +   KL G   +   +A GSLR  +  G  V +   ++      
Sbjct: 60  RNHSIPPHKINYRAN-VYAMKLAGVNRIISISAVGSLRKHIHPGEFVLVDQFVDRTHSRE 118

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIR 203
               +         S+A+    + R+ L++     G      G ++   GP F + AE  
Sbjct: 119 NTFFDGPI--VAHVSIADPVCNQLRSALEQACLASGITTHNGGRYLVMQGPQFSSRAESE 176

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS-DVKLSHAQTLAAAELSK 262
           + +  G DV+GM+ +PE   AR  ++    V+  T+       +  +S    L   + + 
Sbjct: 177 LYRSWGMDVIGMTNMPEAKLAREAEICYATVAMCTDYDCWHGQEEDVSVQSILEVMQANV 236

Query: 263 QNFINLICGF 272
            N   ++  F
Sbjct: 237 ANTQRMLQAF 246


>UniRef50_Q16MW6 Methylthioadenosine phosphorylase n=6 Tax=Neoptera
           RepID=Q16MW6_AEDAE
          Length = 279

 Score =  228 bits (582), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 59/227 (25%), Positives = 97/227 (42%), Gaps = 9/227 (3%)

Query: 59  VSTVHGHAGE-LVLGHLQGVPVVCMKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCT 115
           VST  G+  + L+ G + GV  V +   G  H      +    + I   K +GC  +  +
Sbjct: 29  VSTHFGNPSDVLIEGKIAGVDCVLLARHGRNHSIMPSNVNYRAN-IWALKTVGCTHVIVS 87

Query: 116 NAAGSLRPEVGAGSLVALKDHINTMPGTPMVGL--NDDRFGERFFSLANAYDAEYRALLQ 173
            A GSL+  +  G LV   + I+            ND   G     +  A+ +  R +L 
Sbjct: 88  TATGSLQERIHPGDLVIPDNFIDRTTKRAQTFYDGNDMLVGVCHVPMEPAFCSRTREVLI 147

Query: 174 KVAKEEGFP--LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKV 231
           + AKE G      +G  V+  GP F + AE  + +  G D+V M++VPEV+ A+   L  
Sbjct: 148 ETAKELGLVGVHNKGTVVTIEGPRFSSKAESNLFRQWGADLVNMTLVPEVVLAKEAGLCY 207

Query: 232 VAVSAITNMAEG-LSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
            A++  T+          ++ A  +A  + +      LI   + KIA
Sbjct: 208 AAIAMATDYDCWRDCGENVNVADVMATFKKNVTKVTQLITAVIPKIA 254


>UniRef50_Q60367 Uncharacterized protein MJ0060 n=11 Tax=Methanococcales
           RepID=Y060_METJA
          Length = 252

 Score =  227 bits (579), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 56/218 (25%), Positives = 97/218 (44%), Gaps = 9/218 (4%)

Query: 59  VSTVHGHAGELVLGHLQGVPVVCMKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTN 116
           ++T +G A  ++    +   VV +   G  H      +    + I   K LG E +   N
Sbjct: 22  INTKYGKARVIID---KENEVVLLFRHGVRHNIPPHKINYRAN-IYALKKLGVERILAIN 77

Query: 117 AAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVA 176
           + GSL+ ++  G      D I           ++ +       + + Y  E R +L+ + 
Sbjct: 78  SVGSLKEDLKPGMFFVPNDFIEFTKKREETFYDEGK--VVHIDMTDPYCPELRNILKSIL 135

Query: 177 KEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSA 236
            +  F   EGV+V   GP FET  EI + +  G DVVGM+  PEV+ AR  ++  V++  
Sbjct: 136 DKNNFSYGEGVYVCTEGPRFETKKEIAIYKNWG-DVVGMTGYPEVVLARELEMCYVSLCN 194

Query: 237 ITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLR 274
           ITN A G+S   L+  + L   +  +   + ++  F+ 
Sbjct: 195 ITNYACGISKNILTVDEVLEKIKEMENKILKVVEDFIN 232


>UniRef50_D1C2Y0 Methylthioadenosine phosphorylase n=2 Tax=Bacteria
           RepID=D1C2Y0_SPHTD
          Length = 295

 Score =  227 bits (578), Expect = 4e-58,   Method: Composition-based stats.
 Identities = 57/259 (22%), Positives = 98/259 (37%), Gaps = 15/259 (5%)

Query: 23  DFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM 82
           +    V  I GSGL  +   + +   +      G P       +  L +G L GV V  +
Sbjct: 4   EPRAVVGVIGGSGLYKMP-YLTDVEEVEINTPFGPP-------SAPLAIGTLAGVRVAFL 55

Query: 83  KGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
              G  H Y    +    +     K +G   +   +A GSLR ++    LV     ++  
Sbjct: 56  PRHGRHHEYHPSRVPARAN-FWALKAVGVRRVISVSAVGSLREDIHPLDLVVPDQVVDRT 114

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETA 199
              P    +          LA+ +  E RA L   A      +   G ++   GP F T 
Sbjct: 115 VDRPRTFFDTAP--VVHVELADPFCPEVRAALITAANSVAPRVHSSGTYLCIEGPQFSTR 172

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VKLSHAQTLAAA 258
           AE  + +  G D+VGM+ +PEV  AR  +L    ++ +T+          +S AQ +   
Sbjct: 173 AESELHRRWGMDLVGMTAMPEVRLAREAELCFGILALVTDYDVWHESAEDVSVAQVIQNL 232

Query: 259 ELSKQNFINLICGFLRKIA 277
             + +    ++   +  +A
Sbjct: 233 HQNVETAQAVLRAVIPSLA 251


>UniRef50_B5Y8G4 Methylthioadenosine phosphorylase n=1 Tax=Coprothermobacter
           proteolyticus DSM 5265 RepID=B5Y8G4_COPPD
          Length = 249

 Score =  226 bits (577), Expect = 5e-58,   Method: Composition-based stats.
 Identities = 63/252 (25%), Positives = 110/252 (43%), Gaps = 18/252 (7%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I GSG+      IE   +          V+T +G   ++ L  +    V  +   G
Sbjct: 2   KIGVIGGSGIYQ----IEGVPSTEIS------VNTEYGEV-KVFLAQVDDREVYFLPRHG 50

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + IR  + LG + +  TNA GSL PE+  G++V +   ++   G  
Sbjct: 51  LGHSVPPHLVNYRAN-IRALQGLGAQRIIATNAVGSLNPEIKPGTVVLVDQFLDFTKGRK 109

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
                + +       + N Y  E   +  K+          GV V   GP FETAAE++ 
Sbjct: 110 STFFEEGK--VVHTDMTNPYCPEMIEVASKITTPFPLR-KGGVMVVTEGPRFETAAEVKA 166

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
             ++GGDVVGM+ VPEV+ +R   +  ++++ ++N A GL +  +SH + L   +     
Sbjct: 167 FAMLGGDVVGMTSVPEVVLSREAGMCYLSLAIVSNFAAGLQEQ-VSHEEVLNIMDKLNNQ 225

Query: 265 FINLICGFLRKI 276
               I   ++ +
Sbjct: 226 VQMFILDLIKAM 237


>UniRef50_Q18KQ3 5'-methylthioadenosine phosphorylase MtaP n=4 Tax=Halobacteriaceae
           RepID=Q18KQ3_HALWD
          Length = 301

 Score =  226 bits (577), Expect = 5e-58,   Method: Composition-based stats.
 Identities = 63/258 (24%), Positives = 106/258 (41%), Gaps = 19/258 (7%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQ--GVPVVCMKG 84
            + FI GSG+   A  ++N   I  E   G P       A  L +G +   G  V+ +  
Sbjct: 5   TIGFIGGSGIYE-ALGLQNTHTIEIETPFGEP-------AAPLTVGEVGETGREVIFLPR 56

Query: 85  RG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            G  H Y    +    + I   K  G   +  +NA GSLR E+    LV      +    
Sbjct: 57  HGTSHEYSPTTVPYRAN-IFALKQAGVTHVIASNAVGSLREEISPRMLVIPDQIYDRTKH 115

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP----LTEGVFVSYPGPNFET 198
                 +D          A  Y  E R+++  VA E        + +G +V   GP F T
Sbjct: 116 RTSTFFSDGI--VAHQQFATPYCTELRSIVTDVAMENTAADIDIVKDGTYVCIEGPQFST 173

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
            AE    +  G D++GM+ +PE   AR  +L  V ++ +T+      D +++  + L+ A
Sbjct: 174 RAESEFYRSQGWDIIGMTTIPEAKLAREAELAYVTIAGVTDYDVWKEDTQVTLEEVLSNA 233

Query: 259 ELSKQNFINLICGFLRKI 276
           E +++   +++   +  I
Sbjct: 234 ERNQKAIKSVLTAVINTI 251


>UniRef50_C7MEB8 Purine nucleotide phosphorylase n=2 Tax=Micrococcineae
           RepID=C7MEB8_BRAFD
          Length = 287

 Score =  226 bits (577), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 79/255 (30%), Positives = 125/255 (49%), Gaps = 14/255 (5%)

Query: 26  PRVAFILGSGLGALADQI-ENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGV--PVVCM 82
             +A +LGSG    AD + E         +PGF  + V GH G L    ++G     + +
Sbjct: 28  HDLALVLGSGWSGAADLLGETVWQADATTIPGFRPAAVAGHVGTLRSIRVEGTGARALVL 87

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
             R HFYEG G+  +   +RT    G   +  TN  G + P    G+ V ++D IN    
Sbjct: 88  GARTHFYEGAGVDAVVHGVRTAAATGARTMVLTNGCGGIDPAWAPGTPVLIRDQINFTGA 147

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEI 202
           TP+VG N       F  L + Y    R    ++A++    L EGV++ + GP++ET AE+
Sbjct: 148 TPLVGAN-------FVDLTDLYTPALR----EIARDVDATLDEGVYMQFSGPSYETPAEV 196

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
           +M + +G  +VGMS   E I+ R   + ++ +S +TN+A G+S   LSH + L A   + 
Sbjct: 197 QMAKAMGAHLVGMSTALEAIAVREAGMDLLGISLVTNLAAGISGDALSHEEVLEAGRAAG 256

Query: 263 QNFINLICGFLRKIA 277
                L+   +R+I 
Sbjct: 257 PRISRLLAETVRRIT 271


>UniRef50_B1GZW8 S-methyl-5'-thioadenosine phosphorylase n=1 Tax=uncultured Termite
           group 1 bacterium phylotype Rs-D17 RepID=B1GZW8_UNCTG
          Length = 293

 Score =  226 bits (576), Expect = 8e-58,   Method: Composition-based stats.
 Identities = 58/254 (22%), Positives = 105/254 (41%), Gaps = 14/254 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++AFI GSGL  + D IEN V    +   G P       + +++ G +  +    +   G
Sbjct: 9   KIAFIGGSGLYQI-DGIENIVEKDIDTPFGRP-------SDKIITGVINRINCAFLPRHG 60

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + I   K LG E +    A GSL+ E+     V      +      
Sbjct: 61  RGHILNPSEINQRAN-IYALKSLGTEQIVSFTACGSLKEEIKPKDFVIPDQVFDRTKNRS 119

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIR 203
           +     ++      S+A  +  E R+L+++   E G      G +V   GP F T AE +
Sbjct: 120 LTFF--EKGIVAHVSMAYPFCNEIRSLIRQTVYEIGIKYHFCGTYVCIEGPQFSTKAESQ 177

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
           + +  G  VVGM++ PE   AR  ++    +S +T+        ++++   +A    +  
Sbjct: 178 INRQSGFSVVGMTLFPEAKLAREAEICYANISLVTDFDVWKEREEVTNDAVVANVAANVA 237

Query: 264 NFINLICGFLRKIA 277
           N   +I   + K++
Sbjct: 238 NSRRVIKSLILKLS 251


>UniRef50_Q28ZG3 GA14805 n=2 Tax=pseudoobscura subgroup RepID=Q28ZG3_DROPS
          Length = 333

 Score =  225 bits (575), Expect = 9e-58,   Method: Composition-based stats.
 Identities = 93/286 (32%), Positives = 136/286 (47%), Gaps = 16/286 (5%)

Query: 2   SQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPV-S 60
           S++          + I        PR+  I G  L  L D IE  V I +E +P FPV S
Sbjct: 43  SELYAYGEIEAMAEHIMKVC-QMRPRIGLICGHFLRQLVDIIEEPVLIPFEDIPQFPVCS 101

Query: 61  TVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           T+ G    LV+G + G  V+ M+ R H YEG  +      +R  KL G + +  T AA +
Sbjct: 102 TLEGARNHLVVGTVMGATVMAMQDRFHTYEGYQLASSVLPVRVMKLCGVQHILLTCAAAA 161

Query: 121 LRPEVGAGSLVALKDHINTMP---GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAK 177
           + P+   G ++ +KDHIN +     TP+ G +D RFG R  ++  AYD        ++  
Sbjct: 162 VNPQYAVGDIMLIKDHINMLGMFDRTPLTGAHDPRFGVRKLAMTRAYDRHLIEKSLQIGG 221

Query: 178 EEGFP--LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVS 235
           E GF   L  GVF    GP  +T AE  M++++G D VGMS+V EVI + HC LK+ ++ 
Sbjct: 222 ELGFDDCLQVGVFGCLCGPTCKTNAEGEMLRVMGVDAVGMSLVHEVIVSHHCGLKIFSLG 281

Query: 236 AITNMAEGLSDVKLSHAQTLAAAE--------LSKQNFINLICGFL 273
            IT +A    D +   A+     E           Q   +LI   +
Sbjct: 282 IIT-LAASKDDEQHEVAEAQETQETQEMEMPMQRLQACTDLISRLI 326


>UniRef50_C5C9E7 Purine nucleotide phosphorylase n=3 Tax=Actinomycetales
           RepID=C5C9E7_MICLC
          Length = 301

 Score =  225 bits (573), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 87/273 (31%), Positives = 129/273 (47%), Gaps = 13/273 (4%)

Query: 6   FSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQI-ENAVAISYEKLPGFPVSTVHG 64
                    D I         R+A +LGSG G  A  I +   A+   ++PGF    V G
Sbjct: 40  GFAEARAAADTIARATGVAEHRIAVVLGSGWGEAAGLIGDEVAAVPLAEVPGFHAPKVPG 99

Query: 65  HAGELVLGHL-QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRP 123
           H   +    L  G   +    R HFYE R    +   +RT    G   +  TN  G + P
Sbjct: 100 HNAVIRSVRLPDGTHTLVFGSRTHFYESRDAQAVAHTVRTAAAAGARTVVLTNGCGGMDP 159

Query: 124 EVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL 183
           E+  G+ V + DHIN    TP+        G  F  L + Y    RA    +A+E    L
Sbjct: 160 EIAPGTPVLIADHINLTGATPL-------AGATFVDLTDLYSPRLRA----IAREVDPSL 208

Query: 184 TEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG 243
            EGV+V + GP +ET AE+RM + +GGD+VGMS   + I+ARH  L+V  +S +TN+  G
Sbjct: 209 REGVYVQFAGPQYETPAEVRMARTLGGDLVGMSTALDAIAARHAGLEVFGISLVTNLGAG 268

Query: 244 LSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           +S+  LSHA+ + A + +      L+   + ++
Sbjct: 269 ISETPLSHAEVVEAGQAAGPRIARLLADIVGRL 301


>UniRef50_C4Q4X0 Methylthioadenosine phosphorylase, putative n=1 Tax=Schistosoma
           mansoni RepID=C4Q4X0_SCHMA
          Length = 314

 Score =  224 bits (572), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 59/273 (21%), Positives = 98/273 (35%), Gaps = 32/273 (11%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           +V  I GSG     +  +           G P  T       LV G +  V  V +   G
Sbjct: 5   KVGIIGGSGFDD-PNLFKKVGVRQVTTPFGKPSDT-------LVEGFVGDVACVVLPRHG 56

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + +   K LGC  +  TNA GSL+ ++  G  V L   ++   G  
Sbjct: 57  KGHLIPPSEVNYRAN-VWALKDLGCTHILATNACGSLQEDLVPGDFVVLNQFMDKTWGRE 115

Query: 145 MVGLN---DDRFGERFFSLANAYDAEYRALLQKVAKEEGF-----------------PLT 184
                   D   G     +A  +    R +L + A+ +                      
Sbjct: 116 NTFYGSKPDSLKGVLHMPMAEPFCERTRQILIQAARNKSINVYDKKTMDKSACIHPCVHA 175

Query: 185 EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL 244
           EG  V+  GP F T  E  + + +G D+V M++VPEV  AR   L   +++ +T+     
Sbjct: 176 EGSAVTINGPRFSTRCESFIHKAMGLDIVNMTLVPEVSLAREAGLSYASIAIVTDFDCWK 235

Query: 245 SDVK-LSHAQTLAAAELSKQNFINLICGFLRKI 276
           S+ + +     L     S  +   ++   +  I
Sbjct: 236 SEEEHVCVDMVLEQFRKSVVHVREILLEAVALI 268


>UniRef50_B4U6Q8 Purine phosphorylase family 2 n=2 Tax=Aquificaceae
           RepID=B4U6Q8_HYDS0
          Length = 280

 Score =  223 bits (570), Expect = 4e-57,   Method: Composition-based stats.
 Identities = 54/269 (20%), Positives = 96/269 (35%), Gaps = 36/269 (13%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +  I GSGL  + D +E    +  +   G P S +    G           V  +   G 
Sbjct: 9   LGIIGGSGLYKIFDDVE---ELDIDTPFGKPSSKIFLKNG-----------VAFLSRHGI 54

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H      +    + I     +G   L    A G +     +G +V   D ++       
Sbjct: 55  DHSIPPHLVNYRAN-IYALYKIGVRKLISIGATGGINTLFKSGDIVITSDVLDFTNSRAS 113

Query: 146 VGLND------------------DRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EG 186
                                           ++N +  E   +   ++K+       +G
Sbjct: 114 TFFEGIFSKDIKEQEDTPFYRLLKAKKVVHTDMSNIFCEEMIGIANGISKDLSLHFYVKG 173

Query: 187 VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD 246
           V+    GP FET  E+ M++ +G D+VGM+  PEV  AR   + ++ +S ITN A G+  
Sbjct: 174 VYACTEGPRFETKKEVEMLKHLGADMVGMTACPEVFLARETGMHILHISVITNPAAGIEG 233

Query: 247 VKLSHAQTLAAAELSKQNFINLICGFLRK 275
            KL+  + +   +   +     +  F+ K
Sbjct: 234 HKLTSKEVIDMMKQKDEEIKKFLTLFIPK 262


>UniRef50_Q465I0 Methylthioadenosine phosphorylase n=4 Tax=Methanosarcinaceae
           RepID=Q465I0_METBF
          Length = 258

 Score =  222 bits (567), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 66/258 (25%), Positives = 109/258 (42%), Gaps = 21/258 (8%)

Query: 21  KPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           K      +A + G G  +            Y++     V+T +G     +   ++G  VV
Sbjct: 3   KIPENVEIAVLGGVGFNS------------YQEFESQLVNTPYGEVTVYLT-TVRGKKVV 49

Query: 81  CMKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
            +      +      +    + I     +G + +  TN+ GS+R     GS V L D I+
Sbjct: 50  VIPRHAGENHIPPHRINYRAN-IWAVYSIGAKRVISTNSVGSMRGH-PVGSFVVLDDFID 107

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFET 198
                P    +D         ++  Y  E R  L+   +++G P TEG++    GP FET
Sbjct: 108 FTRNRPSTFYDD---RTAHVDVSEPYCPEIRIALRDALEKQGLPYTEGIYACTEGPRFET 164

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
            AEIRMM     DVVGM+ VPEV  A+   L   +++ +TN A G++  KL+  +     
Sbjct: 165 RAEIRMMSQF-ADVVGMTGVPEVGLAKELSLCYASLAIVTNQACGMTTQKLTADEVTEVV 223

Query: 259 ELSKQNFINLICGFLRKI 276
             ++     +I   + KI
Sbjct: 224 GKAQDAIFEIISDTIEKI 241


>UniRef50_Q09438 Putative S-methyl-5'-thioadenosine phosphorylase n=4 Tax=Metazoa
           RepID=MTAP_CAEEL
          Length = 288

 Score =  222 bits (567), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 49/256 (19%), Positives = 96/256 (37%), Gaps = 15/256 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           +V  I GSGL    + + + V ++ +   G P       + ++V G + GV  V +   G
Sbjct: 3   KVGIIGGSGLED-PNILLDPVTVAVDTPYGKP-------SDDVVEGTINGVECVLLARHG 54

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + +      G +++  + A GSL+  V  G L+      +   G  
Sbjct: 55  RKHDIMPGNVNFRAN-LWALYSRGVDVIIASTACGSLQENVEPGHLLFPDSVFDRTTGRQ 113

Query: 145 MVGLN---DDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAA 200
               +   D   G         Y+ + R +L   A+         G  V   GP F T A
Sbjct: 114 STFFDGSYDQAPGVCHIQAHPTYNEKLRQVLISTAERCQLVHHRTGFGVCIEGPRFSTKA 173

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAEL 260
           E  + +  G  +V M+++PE I A+   +     + +T+      +  ++ +  +     
Sbjct: 174 ESMVFKSWGASLVNMTMMPECILAKELGIPYATTALVTDYDCWKEEDHVTASSVMKVFAA 233

Query: 261 SKQNFINLICGFLRKI 276
           + +    L    + +I
Sbjct: 234 NVEKAKTLFVEAVGEI 249


>UniRef50_Q47F96 Methylthioadenosine phosphorylase n=7 Tax=Betaproteobacteria
           RepID=Q47F96_DECAR
          Length = 256

 Score =  221 bits (563), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 57/252 (22%), Positives = 101/252 (40%), Gaps = 16/252 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGH-AGELVLGHLQGVPVVCMKGRG 86
           +A I GSGL  L++   +   +         V T +G  +G LV G + G P V +   G
Sbjct: 2   LAIIGGSGLTTLSNLDVSHREV---------VRTPYGEASGALVFGQICGQPAVFLPRHG 52

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + +          +    + GS+R ++  G +V     I+   G  
Sbjct: 53  YGHTIPPHMVNYRAN-MWALHHHKVSGVISVASVGSIRGDLQPGDIVLPHQIIDYTWGRK 111

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIR 203
               + +          + YD E R  + +  ++    +  G V+ +  GP  ETAAEI 
Sbjct: 112 STFFDGNGTPVNHIDFTDPYDPELRRRILEAGEQLSIDVKVGAVYAATQGPRLETAAEIN 171

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS-HAQTLA-AAELS 261
            ++  G DVVGM+ +PE + AR       A++ + N A G  +     H ++L    + +
Sbjct: 172 RLERDGADVVGMTGMPEAVLARELGTPYAAINVVANHAAGRGNSANGIHFESLEPVLQEA 231

Query: 262 KQNFINLICGFL 273
                 +I   +
Sbjct: 232 MGRVKAIIEKLV 243


>UniRef50_B9CNR2 Purine nucleoside phosphorylase 1 n=2 Tax=Atopobium
           RepID=B9CNR2_9ACTN
          Length = 396

 Score =  221 bits (563), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 85/269 (31%), Positives = 126/269 (46%), Gaps = 7/269 (2%)

Query: 11  LFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVS--TVHGHAGE 68
           +     ++  KP     VA +LG+GLG LA+ ++    I Y  + GFPV    V GH+ E
Sbjct: 132 VVTEKTVEEIKPSVEHPVALVLGTGLGHLANLVKPVRRIDYRDIEGFPVDAQPVTGHSFE 191

Query: 69  LVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAG 128
             +G + GVPVV   GR H Y+G     +T  ++    LGC  +    A G++    G G
Sbjct: 192 ATIGTIDGVPVVVYPGRVHLYQGYSAAEVTALVQHAHHLGCRDIIFAGATGAVPGNAGTG 251

Query: 129 SLVALKDHINTMPGTPMV-GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGV 187
            L  + D IN     P+            F  + +AY    R L + VA + G  + EG+
Sbjct: 252 -LGIITDQINLTGTNPLAEWAGLKNVETPFVDMNDAYSPYLRTLARGVADDLGITVEEGI 310

Query: 188 FVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDV 247
           F    GPNFET AE+ M++ +     G+S   EVI AR  ++ V+ ++   N A      
Sbjct: 311 FAGLLGPNFETPAEVNMLRAMNVSYTGVSTALEVIMARALNMNVLGLTLAANPAGARG-- 368

Query: 248 KLSHAQTLAAAELSKQNFINLICGFLRKI 276
             +H   L AAE    +F  L+ G LR +
Sbjct: 369 -TTHKSVLEAAEHYADDFERLVRGILRLL 396


>UniRef50_A8B9X8 Purine nucleoside phosphorylase lateral transfer candidate n=3
           Tax=Giardia intestinalis RepID=A8B9X8_GIALA
          Length = 805

 Score =  221 bits (563), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 81/315 (25%), Positives = 136/315 (43%), Gaps = 45/315 (14%)

Query: 6   FSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQI--ENAVAISYEKLPGFPVSTVH 63
           F+ +     D IK         +A +LGSGL   AD++       I YE++P    ++V 
Sbjct: 28  FTSHMHEAADYIKNIIGK-KVDIAVVLGSGLSGFADRMFSTGYTEIDYERVPFMAKTSVS 86

Query: 64  GHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRP 123
           GH+G++++G +    ++C  GR H YEG     +T        LG  +   TNAAG  + 
Sbjct: 87  GHSGKVLVGEMGDKTILCFSGRFHSYEGYTPPTLTIFPYVACYLGARIYIVTNAAGGTKR 146

Query: 124 EVGAGSLVALKDHINTMPGTPMVGLNDDR---------------------------FGER 156
            + AG L+ + D ++ +   P+ G    +                               
Sbjct: 147 GMEAGCLMLINDQMSLLRWNPLYGYESCQLQHDPDCLLELENLKALLGYLKTPGLFHYPS 206

Query: 157 FFSLANAYDAEYRALLQKVAKEEGF---------------PLTEGVFVSYPGPNFETAAE 201
               AN Y AE R+L++++AK++ F                + EG +V   GP++ET  +
Sbjct: 207 SIPNANIYSAELRSLVRELAKDKAFIDKTSIMLKGHKHMVKVYEGTYVLNSGPHYETQID 266

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELS 261
              +  +G   VGMS +PE + AR   + V+ +S +TN+A GLS   L HA     ++  
Sbjct: 267 TETIMSLGPGAVGMSSIPEALCARLLGMHVIGLSVVTNLAAGLSKETLDHADVKLVSDAV 326

Query: 262 KQNFINLICGFLRKI 276
                 LI   + ++
Sbjct: 327 STAVYALIGALIARV 341



 Score = 42.2 bits (98), Expect = 0.020,   Method: Composition-based stats.
 Identities = 15/76 (19%), Positives = 27/76 (35%), Gaps = 6/76 (7%)

Query: 93  GMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDR 152
            +   T   R  ++LG + +           +V    +    D  N      + G NDDR
Sbjct: 656 SLQETTFPARLCQVLGVQRVILIT------DQVQTKDIYCATDVYNVSCVNALRGHNDDR 709

Query: 153 FGERFFSLANAYDAEY 168
           +G RF  ++   +   
Sbjct: 710 WGARFIDVSGICNKGL 725


>UniRef50_A9GWF6 5'-methyl-5-thioadenosine phosphorylase n=1 Tax=Sorangium
           cellulosum 'So ce 56' RepID=A9GWF6_SORC5
          Length = 295

 Score =  220 bits (561), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 56/255 (21%), Positives = 100/255 (39%), Gaps = 17/255 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQG--VPVVCMKGR 85
           +A I GSG+  +   +E+   +S     G P   V       + G ++G    V+ +   
Sbjct: 10  LAIIGGSGVYEM-GWLEDVEEVSVSTPFGLPSDVV-------LRGQVKGGDATVLFLPRH 61

Query: 86  G--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           G  H +    +    + I   K+LG   +   +A GSLR ++  G LV +   I+     
Sbjct: 62  GRGHRFSPSTINYRAN-ICALKMLGATHVLSVSAVGSLREDIAPGDLVVVDQFIDFTKRR 120

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEI 202
                ++          A+       + +   A   G  +  G  +V   GP F T AE 
Sbjct: 121 ISTFFDEGL--VAHVPFADPVCPILASAVHDAALATGARVHRGGTYVCIEGPQFSTRAES 178

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG-LSDVKLSHAQTLAAAELS 261
           RM +  G  V+GM+ +PE   AR  +L    ++  T+     +S+  +S    +A    +
Sbjct: 179 RMFRTFGAHVIGMTNLPEAKLAREAELPYATLALTTDFDCWHVSEEAVSVEAVIAVLNRN 238

Query: 262 KQNFINLICGFLRKI 276
                ++     RK+
Sbjct: 239 IGYARDVAKSLARKL 253


>UniRef50_Q7URV0 Purine nucleoside phosphorylase I n=1 Tax=Rhodopirellula baltica
           RepID=Q7URV0_RHOBA
          Length = 305

 Score =  220 bits (561), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 78/250 (31%), Positives = 120/250 (48%), Gaps = 17/250 (6%)

Query: 40  ADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTD 99
           AD IE+   + Y ++PG   ST  GH GE ++GHL   P++ M GR H YEG  +  +T 
Sbjct: 51  ADAIESPTIVPYAEIPGLAPSTASGHRGEFLIGHLASRPIIAMAGRLHVYEGHSLRDVTR 110

Query: 100 AIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM----PGTPMVG-------- 147
            +     +G   L  + AAG L P+   G LV L +H + +       P+          
Sbjct: 111 PVALMAGIGINELVVSCAAGGLNPQFKVGDLVLLSEHSSWLDGKLGAPPISFQQPISFQQ 170

Query: 148 LND-----DRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEI 202
            ND     D   + F    N  D +  A+  + A   GF L  G++++  GPN+ET AE 
Sbjct: 171 PNDLPNESDAAAKCFRRSLNTCDPQLDAIAHQTAHANGFELRRGMYLAVNGPNYETRAEC 230

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
           RMM+ +G D+VGMS VPE++ A    ++ + +S +TN+A   +     HA  L   E + 
Sbjct: 231 RMMRQLGADLVGMSTVPELLCANSAGVRTLGISVVTNLALPDAPATADHADVLEVCERAA 290

Query: 263 QNFINLICGF 272
                ++   
Sbjct: 291 NRLQQIVRAI 300


>UniRef50_C8R2U4 Methylthioadenosine phosphorylase n=1 Tax=Desulfurivibrio
           alkaliphilus AHT2 RepID=C8R2U4_9DELT
          Length = 254

 Score =  220 bits (560), Expect = 5e-56,   Method: Composition-based stats.
 Identities = 67/257 (26%), Positives = 106/257 (41%), Gaps = 16/257 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           V  I GSGL      IENA  ++ +   G P       +  L+ G + G  V  +   G 
Sbjct: 4   VGIIGGSGLEN-PQLIENAREVTVDTPYGPP-------SAPLLRGRIGGREVALLARHGR 55

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H      +    + +   +  GC  L  + A GSLR ++G G LV     I+      +
Sbjct: 56  EHTIPPSQVNNRANLL-ALQEQGCTHLLASAACGSLRQDIGPGELVIPDQLIDFTRFRAV 114

Query: 146 VGLNDDRFGE---RFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAE 201
              +    G    R  +LA+ + AE R  L    +    PL +G   ++  GP F T AE
Sbjct: 115 TFHDHFPPGIENARHTALADPFAAEIRKQLLMAGRHLELPLHDGGTMLTIEGPRFSTRAE 174

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDV-KLSHAQTLAAAEL 260
            RM Q+ G D+V M++ PE + A    L    V+ +T+      D   L   + +A    
Sbjct: 175 SRMFQLWGADLVNMTIAPEAVLAAELGLPYAVVAMVTDYDSWKEDEPPLQVPELVAVFRG 234

Query: 261 SKQNFINLICGFLRKIA 277
           + +    L+   L ++A
Sbjct: 235 NLEKLSRLLITVLPRLA 251


>UniRef50_B4CZS2 Methylthioadenosine phosphorylase n=1 Tax=Chthoniobacter flavus
           Ellin428 RepID=B4CZS2_9BACT
          Length = 288

 Score =  220 bits (560), Expect = 6e-56,   Method: Composition-based stats.
 Identities = 57/255 (22%), Positives = 99/255 (38%), Gaps = 14/255 (5%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P +  I GSGL  + D + N    + E   G P   + G       G L G  V  +   
Sbjct: 4   PAIGIIGGSGLYQI-DGVTNVTEHTIETPFGAPSDVIVG-------GQLGGRQVYFLPRH 55

Query: 86  G--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           G  H      +    + +   + L    L C  A GSL+ +     +V      +     
Sbjct: 56  GRGHRILPHELNHRAN-LYALRSLNVRWLLCVTAVGSLQEQYAPRHIVLPSQFFDRTSQG 114

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEI 202
           P      +       S A+   A  R L+   A+E G P+   G +V+  GP F T AE 
Sbjct: 115 PAHTFFGNGIA-AHVSFADPTSAPLRQLIVNAARELGLPVHNGGTYVNMDGPAFSTRAES 173

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG-LSDVKLSHAQTLAAAELS 261
              + +G DV+GM+ + E+  AR  ++ V  ++ IT+     + +  ++    +A    +
Sbjct: 174 ETHRKLGFDVIGMTNLGEIRLAREAEIAVATMAMITDYDCWKVEEEPVTADAVIAHLHAN 233

Query: 262 KQNFINLICGFLRKI 276
                 ++   + +I
Sbjct: 234 ADAAKKILARVVPQI 248


>UniRef50_D2VAE0 Purine phosphorylase family protein n=1 Tax=Naegleria gruberi
           RepID=D2VAE0_NAEGR
          Length = 840

 Score =  218 bits (557), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 82/278 (29%), Positives = 133/278 (47%), Gaps = 32/278 (11%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL-----QGVPVVCM 82
           +A +LGSGLG     + NA  +SY ++P  P ++V GH+GEL+LG L     Q   + C 
Sbjct: 24  MAIVLGSGLGDFPKVLLNAKKLSYSQIPHMPQTSVQGHSGELILGELPTNDNQKRLIYCF 83

Query: 83  KGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            GR H YEG     +T  ++    +GC+L   TNA+G L  E+  G L  L  H   +  
Sbjct: 84  AGRIHSYEGGPWDEVTFQVKLMASIGCKLFIMTNASGGLFDEMSGGCLCLLTGHFRLLAR 143

Query: 143 ------------------------TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE 178
                                      +   +D++          + ++Y  L + VAKE
Sbjct: 144 MDPNSLAPGARVSNGQLLETSFEKNEQISQIEDKYSHFAPDY---WTSKYVNLCRSVAKE 200

Query: 179 EGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
           +G  L EG +    GP+FET  E+ M + +GG  VGMS VPE+++  +  ++ + +S + 
Sbjct: 201 QGIKLFEGSYAWASGPSFETPLEVLMAKQLGGACVGMSTVPEMLTCNYYGMECMGISMVC 260

Query: 239 NMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           N+  GL    L+H + L  +++  ++   L+   L KI
Sbjct: 261 NLGAGLQTEPLTHKEVLENSKIGTEHMQLLVKETLSKI 298



 Score = 56.1 bits (134), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 28/140 (20%), Positives = 56/140 (40%), Gaps = 21/140 (15%)

Query: 41  DQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH--------FYEGR 92
           + I+   ++ ++ +P     T  G    L L  +    ++ +    H        +    
Sbjct: 612 ENIKIIKSVPFKNIPHL--QTEFGQ--TLSLATIGDKHILVVH---HIDQSDESTYLRSN 664

Query: 93  GMTIMTDAIRTFKLLGCELLFCTNAA--GSLRPEVGA----GSLVALKDHINTMPGTPMV 146
            +  ++  IR  + L        N+A   +L           +LV  +DHIN     P++
Sbjct: 665 SLIELSFIIRVCQHLHTVNNIYLNSAVVSALNSNFEPIYTPNTLVQYRDHINFTGYNPLI 724

Query: 147 GLNDDRFGERFFSLANAYDA 166
           G N++R+G+RFF ++  Y  
Sbjct: 725 GKNENRWGDRFFDVSGLYRP 744


>UniRef50_C7LA98 FI12502p (Fragment) n=14 Tax=Drosophila RepID=C7LA98_DROME
          Length = 304

 Score =  218 bits (556), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 54/260 (20%), Positives = 101/260 (38%), Gaps = 20/260 (7%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL-GHLQGVPVVCM--K 83
           ++  I  + L            I   +   + V T  G   ++++ G ++GV V  +   
Sbjct: 33  KIGIIGEANLD---------KPIYLAERMEYAVCTPFGKPSDVIIDGQIEGVNVCLLSRN 83

Query: 84  GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           GR H      +    + +   + +GC  +  TN   SLR     G LV   D I+     
Sbjct: 84  GRNHDIMPSNINYRAN-VWAMRKMGCTHILVTNTFSSLRDTFQPGHLVVPNDVIDYTSRR 142

Query: 144 PMVGLND---DRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETA 199
                +       G     +   +    R  L   A+E GFP  + G  ++  GP + T 
Sbjct: 143 AQTFYDGAVGSPLGVCHVPMNPTFCERTRQHLLSAAEELGFPTGSSGTVLTLEGPRYSTV 202

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK--LSHAQTLAA 257
           AE  M +  G D++ M++ PE I A+   +   ++  +TNM    +      +H + +  
Sbjct: 203 AENNMFRKWGADLLSMTLCPEAILAKEAGIPYASLGLVTNMECWCAKQPNATTH-EIIYI 261

Query: 258 AELSKQNFINLICGFLRKIA 277
            +   +N   ++   +R +A
Sbjct: 262 FKKQSENLQKVLITAIRNMA 281


>UniRef50_B5EMB0 Methylthioadenosine phosphorylase n=15 Tax=Proteobacteria
           RepID=B5EMB0_ACIF5
          Length = 270

 Score =  217 bits (554), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 55/252 (21%), Positives = 86/252 (34%), Gaps = 12/252 (4%)

Query: 29  AFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG-- 86
             I GSGL  L + ++           G         +G L  G L G  VV +   G  
Sbjct: 5   GIIGGSGLTGLKN-LQIRHRRVIRTPFGET-------SGPLTFGQLGGQEVVFIARHGYG 56

Query: 87  HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
           H      +    + +     +G   +    A G +   +  G L      I+   G P  
Sbjct: 57  HTIPPHRVNYRAN-VWALHHVGVTHVVAVAAVGGITAAMRPGVLCLPDQLIDYTSGRPST 115

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAEIRMM 205
                         +  Y    R  L + A      +   G + +  GP  ET AEIR +
Sbjct: 116 FFEGGESMVVHIDFSEPYCQPLRERLLQAAGSADIVVIDGGTYAATQGPRLETIAEIRRI 175

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNF 265
           +  GGDVVGM+  PE + AR   L    +S + N A G S   ++            +  
Sbjct: 176 ERDGGDVVGMTGAPEAVLAREIGLCYAPLSLVVNPAAGKSAEPITMEAIDMVMHEGMEKV 235

Query: 266 INLICGFLRKIA 277
             ++   +  +A
Sbjct: 236 RKVLGNVVPLLA 247


>UniRef50_C5EEL8 Purine nucleoside phosphorylase n=1 Tax=Clostridiales bacterium
           1_7_47FAA RepID=C5EEL8_9FIRM
          Length = 259

 Score =  217 bits (553), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 63/257 (24%), Positives = 99/257 (38%), Gaps = 21/257 (8%)

Query: 24  FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
             P V  I GSG   L   +EN           F  +  +G + E+  G +QG  V  + 
Sbjct: 1   MKP-VGIIGGSGFYEL---LENPRM--------FVHNNKYGRSSEIFEGTIQGRKVYFLP 48

Query: 84  GRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMP 141
             G  H      +    + I  FK LG E +  TN  GS  P++  GSLV   D  +   
Sbjct: 49  RHGEEHKIIVPRINYRAN-IWAFKELGVEQILATNCVGSSNPDIELGSLVIPHDFCDWTR 107

Query: 142 GTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE--GFPLTEGVFVSYPGPNFETA 199
             P   L DD        +  AY  + R  L   A +   G    + V     G  FET 
Sbjct: 108 RFP-RSLYDDEVEAYHVDMTPAYCPDLRRALIDAANKVKPGHVHDKAVIFVNEGLRFETP 166

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAE 259
            E+ M + +G D++GM+ +PE + AR   +    +   TN   G    ++         +
Sbjct: 167 FELTMFRKLGADLIGMTTLPEAVFAREAAICYAHICVPTNWCLG---EQIEADDFPRLLK 223

Query: 260 LSKQNFINLICGFLRKI 276
              ++F  ++   +  +
Sbjct: 224 QGIEDFKQVLYLAIPDL 240


>UniRef50_Q5Z1K2 Putative methylthioadenosine phosphorylase n=4
           Tax=Corynebacterineae RepID=Q5Z1K2_NOCFA
          Length = 269

 Score =  216 bits (551), Expect = 5e-55,   Method: Composition-based stats.
 Identities = 67/255 (26%), Positives = 103/255 (40%), Gaps = 16/255 (6%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
            P +A I G+G     D     V I      G P       +  + +G + G PV  +  
Sbjct: 6   RPALAVIGGTGFYDFFDTATQDVEID--TPYGAP-------SAPIAVGEVAGRPVAFVPR 56

Query: 85  RG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            G  H Y    +  + + +   + LG   +F   A GSLR + G G++   +  ++   G
Sbjct: 57  HGKRHEYAPHTLPYLAN-MWALRSLGVRRIFAPCAVGSLRADWGPGTVAVPEQLVDRTSG 115

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEI 202
            P    +    G    S A+ Y  E R      A EE      G  V   GP F T AE 
Sbjct: 116 RPQTYFD---GGGVHVSFADPYCDELRGAAIGSAVEELPMQPGGTMVVVQGPRFSTRAES 172

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA-QTLAAAELS 261
           R     G D+V M+  PE + AR  ++   AV+ +T++  GL   +  HA    A  + +
Sbjct: 173 RWFAGQGWDLVNMTGYPEAVLARELEMCYCAVALVTDLDAGLESGEGVHAVDVFAEFKRN 232

Query: 262 KQNFINLICGFLRKI 276
            + F  LI G +  +
Sbjct: 233 IEPFKELIRGAISAV 247


>UniRef50_Q87ZC3 Probable S-methyl-5'-thioadenosine phosphorylase n=45 Tax=cellular
           organisms RepID=MTNP_PSESM
          Length = 246

 Score =  215 bits (549), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 60/249 (24%), Positives = 94/249 (37%), Gaps = 12/249 (4%)

Query: 29  AFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHF 88
           A I G+GL  L + +    ++      G P       +GE+ +G   G  V+ +   GH 
Sbjct: 5   AIIGGTGLTQL-EGLNIRQSLPMNTPYGAP-------SGEIQIGDYAGREVMFLARHGHP 56

Query: 89  Y--EGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
           +      +    + I   K  G E +   NA G + P +G G      D ++   G    
Sbjct: 57  HRLPPHQVNYRAN-IWALKQAGAEAILAVNAVGGIHPAMGTGHFCVPHDLVDYTSGRQHT 115

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAEIRMM 205
              DD         +  Y    R  L      EG      GV+    GP  ET AEI  +
Sbjct: 116 FFADDLEEVTHIDFSYPYSEALRVRLVAALAAEGCAFSDRGVYACTQGPRLETVAEIIRL 175

Query: 206 QIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNF 265
           +  G D+VGM+ +PE   AR  +L+   ++ + N A G S   ++ A+   A        
Sbjct: 176 ERDGCDIVGMTGMPEAALARELELEYACLALVVNPAAGKSTAVITMAEIEQALRDGMGKV 235

Query: 266 INLICGFLR 274
              +   L 
Sbjct: 236 KATLARVLS 244


>UniRef50_C6DE56 Methylthioadenosine phosphorylase n=1 Tax=Pectobacterium
           carotovorum subsp. carotovorum PC1 RepID=C6DE56_PECCP
          Length = 301

 Score =  213 bits (543), Expect = 5e-54,   Method: Composition-based stats.
 Identities = 61/262 (23%), Positives = 104/262 (39%), Gaps = 15/262 (5%)

Query: 20  YKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPV 79
            +    PR+  I GSG+ +L+  IE    I+     G P       +G + LG + GVPV
Sbjct: 4   QRTTTPPRIGIICGSGMDSLS-IIEAPERINVTTSFGDP-------SGIITLGEIAGVPV 55

Query: 80  VCMKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHI 137
             +   G  H      + +  + I   K LG   +   +A GSL  E   G+ VA+  +I
Sbjct: 56  AIVNRHGIGHRLLPSEINVRAN-IAALKALGVSQVISFSAVGSLVEEAPPGTFVAIDQYI 114

Query: 138 NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNF 196
           +                            +  +LL     E   P   +G++V   GP+F
Sbjct: 115 DRTYRRVNTFF--GSGVVAHVPFGKPVCTDNHSLLVDALGELSIPHLAKGLYVVMEGPHF 172

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VKLSHAQTL 255
            T AE    + +GG V+GM+ +PE    R  +L    V+ +T+     +    ++ A   
Sbjct: 173 STKAESAFHRQMGGTVIGMTAMPEPKLCREAELCYNMVAMVTDYDCWHTSHEAVNAAMVS 232

Query: 256 AAAELSKQNFINLICGFLRKIA 277
                + +   +L+   + K+A
Sbjct: 233 EQMADNIKKAESLLSVIVPKLA 254


>UniRef50_Q21JS6 Methylthioadenosine phosphorylase n=1 Tax=Saccharophagus degradans
           2-40 RepID=Q21JS6_SACD2
          Length = 252

 Score =  213 bits (543), Expect = 5e-54,   Method: Composition-based stats.
 Identities = 62/256 (24%), Positives = 98/256 (38%), Gaps = 17/256 (6%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++A I GSG   +A    NA A++       PV+T +G  G L+   + G  +V +   G
Sbjct: 4   KIAVIGGSGFYTMASA-NNAKALN-------PVNTPYGSVGGLIEYSMGGHNIVFLARHG 55

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + I   K LG   +   NA G +    G G LV     I+   G  
Sbjct: 56  GEHKLPPHKINYRAN-IYALKELGVSHIIAANAVGGIGERCGPGVLVIPDQLIDYTFGRE 114

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE------EGFPLTEGVFVSYPGPNFET 198
               +    G         ++   R  L + +            +  GV+    GP  ET
Sbjct: 115 GTFFDSFEDGMSHIDFTYPFEGRVRNALIQASAAFEKEFGSDKVVRNGVYACMQGPRLET 174

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
           AAEI+ ++  G  +VGM+ +PE   AR   +   ++  + N A GLS   ++     A  
Sbjct: 175 AAEIKKLKNDGASLVGMTAMPEAALARELGIDYASICLVVNWAAGLSAGLITLEAINAEL 234

Query: 259 ELSKQNFINLICGFLR 274
           E        LI   + 
Sbjct: 235 EGCVGKAEYLIGQSVN 250


>UniRef50_D2V2R7 5'-methylthioadenosine phosphorylase n=1 Tax=Naegleria gruberi
           RepID=D2V2R7_NAEGR
          Length = 299

 Score =  212 bits (541), Expect = 8e-54,   Method: Composition-based stats.
 Identities = 53/254 (20%), Positives = 93/254 (36%), Gaps = 17/254 (6%)

Query: 27  RVAFILGSGLGALADQIENAVAI-SYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
            +AFI G+GL   A+ +EN + +  +E   G P S        +V+G + G+ V  +   
Sbjct: 13  DLAFIGGTGLSK-AEGLENVITVEPFETPFGKPSSP-------IVIGTINGLTVAFLCRH 64

Query: 86  G--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           G  H  +   +    + I   K LG   L    A GSL+ E+     V +   I+     
Sbjct: 65  GLSHSVQPTDVPYRAN-IFALKSLGANNLVSFGAVGSLQEELAPKHFVVVDQFIDRTKFR 123

Query: 144 PM-VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE---GFPLTEGVFVSYPGPNFETA 199
                  D        S           L+                G +V   GP F + 
Sbjct: 124 QSENTFYDREGLVAHVSFGEPTCKTLSQLVVDSCSRIETIPKTHATGTYVCMEGPCFSSR 183

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VKLSHAQTLAAA 258
           AE +M ++ GG ++GM+ + E   AR  ++    V  +T+      +   ++  + +   
Sbjct: 184 AESKMYRMWGGSIIGMTCLQEAKLAREAEMAFACVGMVTDYDAWKDEAEPVTVEEVVKIL 243

Query: 259 ELSKQNFINLICGF 272
             +  N   +I   
Sbjct: 244 HDNGDNARRVIQEV 257


>UniRef50_Q1H1A2 Methylthioadenosine phosphorylase n=3 Tax=Bacteria
           RepID=Q1H1A2_METFK
          Length = 248

 Score =  212 bits (539), Expect = 1e-53,   Method: Composition-based stats.
 Identities = 53/251 (21%), Positives = 88/251 (35%), Gaps = 14/251 (5%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +  I G+GL  LA+ ++           G P       +G L  G + G  V+ +   GH
Sbjct: 2   LGIIGGTGLTKLAN-LKIKRRQIVRTPYGEP-------SGPLTYGDICGYEVIFLPRHGH 53

Query: 88  FY--EGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            +      +    + I      G   +    + G + P +  G +      I+   G   
Sbjct: 54  GHTIPPHIVNYRAN-IWALHAEGVRDIVSVASVGGIHPRLDPGVIALPDQIIDYTHGRKN 112

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAEIRM 204
              +      +       Y    R L  + A      +   GV+    GP  ETAAEI  
Sbjct: 113 TYYDGGDLPVKHIDFTMPYSDRLRNLCLEAATNISESIIDGGVYACVQGPRLETAAEINR 172

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK--LSHAQTLAAAELSK 262
           ++  G  +VGM+ +PE   AR  D+   A+  + N A G       + +         + 
Sbjct: 173 LERDGATMVGMTGMPEAALARELDMHYAAICPVANHAAGRGSSAKGIQYDNMGDVLNKTM 232

Query: 263 QNFINLICGFL 273
           Q   NLI   +
Sbjct: 233 QRVRNLIERVV 243


>UniRef50_B0DVC8 Predicted protein n=3 Tax=Basidiomycota RepID=B0DVC8_LACBS
          Length = 315

 Score =  211 bits (538), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 59/256 (23%), Positives = 95/256 (37%), Gaps = 19/256 (7%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +  I GSGL  L D +     ++ E   GFP S++   A         G  V  +   G 
Sbjct: 9   IGIIGGSGLYHL-DNLTQITTVNPETPWGFPSSSITIAALP------SGTRVAFLARHGQ 61

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H      +    + I   K LG   +   +A GSLR E+  GS V     I+   G   
Sbjct: 62  GHVIPPSSVPGRAN-IAALKSLGVRAIIAFSAVGSLREEISPGSFVLPTQIIDRTKGIRP 120

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQK------VAKEEGFPLTEG-VFVSYPGPNFET 198
               +           + +  +    L++       A+ +G  L  G   V   GP F T
Sbjct: 121 ASFFEGTSIVAHAMFGDPFSGKLVKWLEERVRKALDAEGKGAKLFTGKCIVCMEGPQFST 180

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG-LSDVKLSHAQTLAA 257
            AE  M +  GGD++ MSV+PE   AR  +L    ++  T+          ++ A     
Sbjct: 181 RAESLMYRQWGGDLINMSVLPEAKLAREAELSYALIATATDYDSWRDQSESVTAADVFKT 240

Query: 258 AELSKQNFINLICGFL 273
            + + +    L+   +
Sbjct: 241 LKGNAET-SRLVAATI 255


>UniRef50_Q87BR7 Probable S-methyl-5'-thioadenosine phosphorylase n=16 Tax=Bacteria
           RepID=MTNP_XYLFT
          Length = 248

 Score =  211 bits (537), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 59/252 (23%), Positives = 97/252 (38%), Gaps = 13/252 (5%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +A I G+G+  L+ Q ++      E L G P       +G + +G L G  V      G 
Sbjct: 6   LAVIGGTGVYTLS-QFDDVQVYEVETLYGRP-------SGPIRVGMLFGQRVAFFARHGE 57

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H      +    + I   + LG   +   N  G +    G  +LV     I+   G   
Sbjct: 58  EHALPPHKINYRAN-IAALQQLGVSRVLALNTVGGINEAFGPRTLVCPDQLIDYTWGRVS 116

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRM 204
               +           + Y    R  L + A++    L E G +    GP  ET AEI  
Sbjct: 117 TFCEEVGSEVLHVDFGHPYSPLLRGCLLRAARDVDVSLVEYGCYGVTQGPRLETIAEIDR 176

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VKLSHAQTLAAAELSKQ 263
           ++  G D+VGM+ +PE   AR   L+   +  ++N A G  D  +++  + L+    +  
Sbjct: 177 LRRDGCDLVGMTGMPEAALAREKGLEYACLGIVSNWAAGCGDGAEITMGEILSNVATAFS 236

Query: 264 NFINLICGFLRK 275
               LI    R+
Sbjct: 237 CLPELISKVARE 248


>UniRef50_B9KXK8 Purine nucleoside phosphorylase n=2 Tax=Thermomicrobia (class)
           RepID=B9KXK8_THERP
          Length = 289

 Score =  210 bits (536), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 90/266 (33%), Positives = 125/266 (46%), Gaps = 6/266 (2%)

Query: 15  DIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHL 74
             I   +   TP    +LGSGL  L +       +  ++L       V GH  ELVL   
Sbjct: 15  AQILAQRYHHTPDALIVLGSGLATLPEDAHVVARVPLDELTAIAAPAVTGHPRELVLAEW 74

Query: 75  QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALK 134
            G P+    GR H Y+G         I     L   ++  TNAAGSL P    G LV ++
Sbjct: 75  NGHPIWFCLGRYHLYQGLSAAEAAAPIALLAHLPGPIVILTNAAGSLHPTFAPGDLVLIR 134

Query: 135 DHI---NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSY 191
           DH          P++         RFFSL +AYD   RA+ +  A   G  L EG +   
Sbjct: 135 DHFFVPGLAGHHPLI---PPAGRVRFFSLRDAYDRHLRAVARAAAARLGLELPEGTYAMV 191

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH 251
            GP FETAAE+R ++  G D+VGMS +PEVI AR   L+V+A+S +TN+A        +H
Sbjct: 192 AGPTFETAAELRWLRAAGADLVGMSTIPEVILARALGLRVLAISVVTNLAIPEEPAIPTH 251

Query: 252 AQTLAAAELSKQNFINLICGFLRKIA 277
            +  A  E ++     L+  FL ++A
Sbjct: 252 EEVAAIGEQARPRLHRLLGFFLDQLA 277


>UniRef50_A3TNF6 Methylthioadenosine phosphorylase n=1 Tax=Janibacter sp. HTCC2649
           RepID=A3TNF6_9MICO
          Length = 272

 Score =  210 bits (534), Expect = 5e-53,   Method: Composition-based stats.
 Identities = 66/254 (25%), Positives = 104/254 (40%), Gaps = 14/254 (5%)

Query: 24  FTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
               +  I G+G   L D +++A + + +   G    T          G   G PVV + 
Sbjct: 5   TRHPLGIIAGTGFYDL-DALDDARSETVDTAYGPTSVT---------QGSWHGQPVVFVT 54

Query: 84  GRGHFYEGRGMTIMTDAI-RTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
             G  +E     +   AI R    LG   +   N  G + P++ AG +V + D ++    
Sbjct: 55  RHGAGHEVPPHMVNYRAIVRALADLGVHDVIAVNVTGGIDPDLEAGEIVVIDDFLDFTRQ 114

Query: 143 TPMVGLN-DDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAA 200
                 + D   G     +  AYD   R  L   A   G  +   GV+V + GP FE+ A
Sbjct: 115 RSATFHDGDGPEGVVHTDMTTAYDPVLRRELLDAASAIGQSVIDGGVYVCFDGPRFESPA 174

Query: 201 EIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL-SDVKLSHAQTLAAAE 259
           EIR+  + GG V GM+ VPEV  A    L+  A+S + N A G+     ++  +  A  E
Sbjct: 175 EIRLAALAGGTVAGMTGVPEVTLAAEAGLRYAALSLVVNPAAGVRPGEPITMDEISAVLE 234

Query: 260 LSKQNFINLICGFL 273
                 + +I   +
Sbjct: 235 TGAPKVLAVIDELV 248


>UniRef50_Q9W1K6 CG18128 n=7 Tax=melanogaster group RepID=Q9W1K6_DROME
          Length = 339

 Score =  209 bits (533), Expect = 7e-53,   Method: Composition-based stats.
 Identities = 80/270 (29%), Positives = 117/270 (43%), Gaps = 10/270 (3%)

Query: 2   SQVQF--SHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPV 59
            Q  F            I        P+   I GS L  +   +E  V I YE +P FP 
Sbjct: 40  PQSLFYPFEEVEAMAKYIV-NVSHIRPKYGLICGSFLSDMVSLVEQPVVIPYEDIPNFPD 98

Query: 60  STVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAG 119
                 +   VLG + G P++ +    H  +G  +      +R  +L G   +  T+ A 
Sbjct: 99  GIEPDCS--FVLGTVMGAPIIALVHSFHSCDGYNLATCALPVRVMQLCGVRTIMLTSEAA 156

Query: 120 SLRPEVGAGSLVALKDHIN---TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVA 176
           ++      G ++ ++DHIN    M  TP+ G +D RFG R FS+ NAYD +      ++ 
Sbjct: 157 AVDHGFALGDIMLVQDHINVVGMMHQTPLEGPSDPRFGSRRFSMVNAYDKDLLEKALEIG 216

Query: 177 KEEGFP--LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAV 234
           K  G    L  GV     GP   T AE RM++ +    VGMS+VPEVI+A H  LKV+A 
Sbjct: 217 KRMGIQKFLHSGVLACMGGPILGTVAEERMLRTMEVSAVGMSLVPEVIAAHHGGLKVLAF 276

Query: 235 SAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
             I+  A      +    +       SKQ+
Sbjct: 277 VVISRAASDKESEESDKDKEKDTDRDSKQD 306


>UniRef50_C5TP90 Methylthioadenosine phosphorylase n=5 Tax=Neisseria
           RepID=C5TP90_NEIFL
          Length = 238

 Score =  208 bits (531), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 54/241 (22%), Positives = 89/241 (36%), Gaps = 15/241 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +A I GSGL  L + +E           G   S        ++ G L  + +V +   G 
Sbjct: 2   LAIIGGSGLTKLPE-LEITERKIVRTPYGLTSSP-------ILFGRLGRLDIVFLARHGF 53

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H      +    + I     LG E +   ++   + P+   GSLV   D I+   G   
Sbjct: 54  SHTIAPHEINYRAN-IWALHSLGVENIIAISSVVGINPDFENGSLVLPDDLIDYTYGRKD 112

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRM 204
                           N Y  E R  L  + K    P+ +  V+    GP   T AEI  
Sbjct: 113 TFFEGQECPVVHTDFFNPYCDELRQELLNITKAHNVPIYDSAVYGCLQGPRRPTRAEIAR 172

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVV---AVSAITNMAEGLSDVKLSHAQTLAAAELS 261
            +  G DV+GM+ +PE + AR   +      +VS+I     G+     +   ++   ++ 
Sbjct: 173 YRRDGVDVLGMTGMPEAVLARELKMAYAHFCSVSSIDCFDSGVGTEGCNEQTSMTMTKIR 232

Query: 262 K 262
           +
Sbjct: 233 Q 233


>UniRef50_B7RUB3 Phosphorylases family 2 n=1 Tax=marine gamma proteobacterium
           HTCC2148 RepID=B7RUB3_9GAMM
          Length = 246

 Score =  207 bits (527), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 62/252 (24%), Positives = 92/252 (36%), Gaps = 12/252 (4%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
            +  I G+G+  L + +E   + + E   G P   V         G L GV V  ++  G
Sbjct: 3   TLGIIGGTGIDQL-EGLEIVDSHAVETPYGDPSRAVE-------EGMLGGVRVFFLQRHG 54

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
                    +    + +   K L    L   NA G +   +  G LV     ++   G  
Sbjct: 55  SPKTIPPHLINYRAN-VWALKSLQVTDLVAINAVGGISAAMRPGRLVIPDQIVDYTWGRA 113

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIR 203
                 +         ++ YD E R  L + A  +       GV     GP  E+AAEIR
Sbjct: 114 HTVDTGEVGTLLHVDFSDPYDHELREALLQCAVAQNIAHEGAGVHGVMQGPRLESAAEIR 173

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
            M   G D+VGM+ +PE   AR   L   ++  + N A GL D  L+ A   A       
Sbjct: 174 RMAGDGCDLVGMTGMPEASLARELGLAYASICMVVNAAAGLDDKPLTLAVMRANLLREAA 233

Query: 264 NFINLICGFLRK 275
               LI   +  
Sbjct: 234 AVRQLIAALVAD 245


>UniRef50_Q09816 Uncharacterized protein C16C9.02c n=49 Tax=cellular organisms
           RepID=YAC2_SCHPO
          Length = 307

 Score =  206 bits (525), Expect = 6e-52,   Method: Composition-based stats.
 Identities = 50/261 (19%), Positives = 91/261 (34%), Gaps = 22/261 (8%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +  I GSG   L    +   +++     G+P S +       +     G  +  +   G 
Sbjct: 10  LGVIGGSGFYDLP-GFDIVESVNPITPWGYPASPIS------IARTTSGFLIAFLARHGV 62

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM-PGTP 144
            H Y    +    + I   K LG   +   +A GSLR ++     V     I+      P
Sbjct: 63  GHIYTPTEVPSRAN-IAALKSLGVLAIVSFSAVGSLREDIPPEDFVLPTQIIDRTLCARP 121

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE--GFPLT---EG---VFVSYPGPNF 196
                         S  + +D +   +L         G  L    +G     V   GP F
Sbjct: 122 NTFFESGC--VAHVSFGDPFDQDLYEILSSCGSNLKNGSKLHTKRKGDDLTVVCMEGPAF 179

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG-LSDVKLSHAQTL 255
            T AE  + +  G  ++ MSV+PE   AR  ++    V   T+     +++  ++    +
Sbjct: 180 STRAESNLYRSWGASIINMSVIPEAKLAREAEIAYQMVCMATDYDCWRMNEEPVTVETVM 239

Query: 256 AAAELSKQNFINLICGFLRKI 276
                +K N    +   ++K+
Sbjct: 240 EHISNNKDNAKIFLLEAVKKL 260


>UniRef50_A2QWR2 Contig An11c0240, complete genome n=24 Tax=Leotiomyceta
           RepID=A2QWR2_ASPNC
          Length = 311

 Score =  205 bits (523), Expect = 9e-52,   Method: Composition-based stats.
 Identities = 48/259 (18%), Positives = 89/259 (34%), Gaps = 13/259 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           R+A I G+GL  L        +++     G P S +          + Q V +  +   G
Sbjct: 13  RIAVIGGTGLRELP-GFTQVASLNVATPWGNPSSPITILH-HKCSHNNQTVAIAFLSRHG 70

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG-T 143
             H      +    + I   + +G   +   +A GSL+ E+     V     I+   G  
Sbjct: 71  LHHQIAPHEVPARAN-IAALRSIGVRTIIAFSAVGSLQEEIKPRDFVVPDQVIDRTKGIR 129

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE---GFPLT-EGVFVSYPGPNFETA 199
           P                 + +D     +++         G  L   G  +   GP F T 
Sbjct: 130 PFTFFEGG--VVAHVPFGDPFDEGVAKVVRACGHSLEGEGVVLHDRGTLICMEGPQFSTR 187

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VKLSHAQTLAAA 258
           AE ++ +  GG V+ MS +PE   AR  ++    +   T+          ++    +   
Sbjct: 188 AESKLYRSWGGSVINMSCLPEAKLAREAEIAYQMICMSTDYDCWHESTADVTVEMVMGNM 247

Query: 259 ELSKQNFINLICGFLRKIA 277
           + +  N    +   L ++A
Sbjct: 248 KANAVNAKRFVTAVLDELA 266


>UniRef50_A4X3Q9 Methylthioadenosine phosphorylase n=8 Tax=Actinomycetales
           RepID=A4X3Q9_SALTO
          Length = 267

 Score =  205 bits (523), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 54/259 (20%), Positives = 96/259 (37%), Gaps = 20/259 (7%)

Query: 22  PDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHG-HAGELVLGHLQGVPVV 80
           P+    +  I G+GL  L  + E              +ST +G  +  + +  L    V 
Sbjct: 4   PNLNADIGVIGGTGLYELLGETEEVK-----------ISTPYGAPSDLITVAELNSRQVA 52

Query: 81  CMKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
            +   G  H +    +    + I   + LG   +    A G LRP+  AG+ V     I+
Sbjct: 53  FLPRHGRDHRFPPHRIPYRAN-IWALRSLGVRQILAPCAVGGLRPDFIAGTFVVPDQLID 111

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFET 198
              G      +    G    + A  Y  + R      A+     +  G  V   GP F T
Sbjct: 112 RTSGREQTFCD---TGAVHTTFAEPYCPDGRRAALAAAERVN-RVDGGTMVVIDGPRFST 167

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQTLAA 257
            AE R     GG ++ M+  PE   AR   L   +++ +T++  G+   + ++H + L A
Sbjct: 168 RAESRWHAAAGGTIINMTGQPEAALARELALCYTSIALVTDLDAGVEGSQGVTHDEVLRA 227

Query: 258 AELSKQNFINLICGFLRKI 276
              +      ++   +  +
Sbjct: 228 FAKNVTVLRRVLFDAVAAL 246


>UniRef50_B3RV47 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
           RepID=B3RV47_TRIAD
          Length = 294

 Score =  205 bits (522), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 76/277 (27%), Positives = 132/277 (47%), Gaps = 12/277 (4%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGE-LV 70
              + ++  K   +P++  + G GL A+A+ I+    IS   LP FP       +   L+
Sbjct: 16  TIANYLR-KKTRLSPKIGLVCGKGLDAVANIIQKKQVISCSSLPCFPSPNYKATSDHDLI 74

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
            G + G PV+C++G+ H YEG  +  +   I+    LG E+L     + SL P+   G +
Sbjct: 75  FGLVSGKPVICIQGQYHMYEGFSIETVILPIKIMFALGVEILLTIGVSRSLNPDFDIGDI 134

Query: 131 VALKDHINT--MPGTPMVGLNDDRFGER----FFSLANAYDAEYRALLQKVAKEEGFP-- 182
           V +KDHIN   + GT        +   +        +NAYD   R++++  A+  G    
Sbjct: 135 VLVKDHINLPSLCGTDSACYGTTKQTRQLNGTPIVKSNAYDVRLRSVVESSARTCGIGEL 194

Query: 183 LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAE 242
           + +G  +   GP+ E+ AE+R ++ +G D++ M  VPEV    HC++++ A+  IT    
Sbjct: 195 IRQGTLMFVSGPSLESNAELRFIRTLGMDMLAMDTVPEVTMGMHCNMRICALLIITYKDV 254

Query: 243 GLS-DVKLSHA-QTLAAAELSKQNFINLICGFLRKIA 277
           G      +S   Q L  A +   +  +L+C  +  I 
Sbjct: 255 GSEIGGDVSMEHQMLETARVRITDLQSLVCNVIGTIT 291


>UniRef50_B5YKP5 S-methyl-5-thioadenosine phosphorylase n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YKP5_THEYD
          Length = 265

 Score =  204 bits (520), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 59/258 (22%), Positives = 104/258 (40%), Gaps = 17/258 (6%)

Query: 23  DFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM 82
               ++  I GSGL    +       I+ +   G P               +  + V+ +
Sbjct: 4   KQQVKIGIIGGSGLS---ESEAKKEIITIKTPYGEPSCPYEIE-------KIDDIEVLFL 53

Query: 83  KGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
           +  G  H      +    + I  FK  G E +F   A GSL   +  GS+V     I+  
Sbjct: 54  RRHGQKHSIPPHKVNYRAN-IYGFKNFGIERIFGVFATGSLTENIPPGSIVIPNQIIDFT 112

Query: 141 -PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFET 198
                     + +           + +E R  L + A++ G  + +   ++   GP  ET
Sbjct: 113 QGMRANTFYEEKK--VVHIDFTEPFCSEIRHYLLETARKIGINVISHATYICVNGPRLET 170

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
           AAEI+  + IG D++GM+++PE   AR  ++   AV+ + N A G+S   L+  + +   
Sbjct: 171 AAEIKFFKNIGADIIGMTIMPEASLAREVEICYAAVAVVANYAAGISKFPLTVKEVIETM 230

Query: 259 ELSKQNFINLICGFLRKI 276
           E S      LI   ++K+
Sbjct: 231 EDSLDAVGFLIKETIKKL 248


>UniRef50_Q2BRI1 Methylthioadenosine phosphorylase n=1 Tax=Neptuniibacter
           caesariensis RepID=Q2BRI1_9GAMM
          Length = 283

 Score =  203 bits (518), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 54/254 (21%), Positives = 95/254 (37%), Gaps = 16/254 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +A I G+G+  L + +E       E   G P       +  +  G +    ++ +   G 
Sbjct: 2   LAIIGGTGIYQL-EGLEVMGEHELETPFGSP-------SAAITQGKMADQDLLFLPRHGR 53

Query: 88  FYE--GRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            +E     +    + I   K LG   +   +A GSL+ E+  G L     + + + G   
Sbjct: 54  RHELLPSEVNYRAN-IWALKKLGATQVIGLSAVGSLQEEIAPGDLSLPDQYFDFVKGNRE 112

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRM 204
                +       S A          L+K A+  G  +     +    GP   T AE   
Sbjct: 113 KTFFGNGLA-AHVSTAEPTSKCLADGLEKAAESVGQKVHRNKTYACVDGPRLGTRAESFF 171

Query: 205 MQ-IIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD--VKLSHAQTLAAAELS 261
           ++   G D+VGM+ VPEV  AR   L    ++  T+    L D    +S  Q +A    S
Sbjct: 172 LRGAAGCDLVGMTNVPEVFLAREAQLCYCTIAIATDYDCWLDDPAQHVSVEQVIARYGAS 231

Query: 262 KQNFINLICGFLRK 275
            +    ++  ++ +
Sbjct: 232 LEKAKQVLTAYITQ 245


>UniRef50_Q5KPU2 Glutamate biosynthesis-related protein, putative n=2
           Tax=Agaricomycotina RepID=Q5KPU2_CRYNE
          Length = 303

 Score =  203 bits (518), Expect = 4e-51,   Method: Composition-based stats.
 Identities = 60/258 (23%), Positives = 95/258 (36%), Gaps = 17/258 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           V  I GSGL  L D +     +  E   G P S ++  +         G  V  +   G 
Sbjct: 9   VGCIGGSGLYHL-DNLTFVKTVHIETPWGKPSSPINISSLP------SGALVAFISRHGS 61

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H      +    + I   K +GCE +   +A GSLR E+  G  +     I+   G   
Sbjct: 62  HHSITPSEVPCRAN-IAALKHIGCEAIIAFSAVGSLREEIAPGHFIIPDQIIDRTKGIRE 120

Query: 146 VGLNDDRFGERFFSLANAYDAEYRA----LLQKVAKEEG-FPLTEG-VFVSYPGPNFETA 199
                             +  +  A     ++K+ KE G   L  G   V   GP F T 
Sbjct: 121 DTFFRGEGLVVHSMFGEPFSQKLNAFVAPRVEKILKETGDVVLHTGKTVVCMEGPAFSTR 180

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VKLSHAQTLAAA 258
           AE  M +  GGD++ MSV+PE   AR  +L    +   T+     +    ++  + +   
Sbjct: 181 AESLMYRQWGGDIINMSVIPEAKLAREAELDYTLICTSTDFDAWRTGYDPVTVEEVVKVL 240

Query: 259 ELSKQNFINLICGFLRKI 276
             +  N   +  G L+ +
Sbjct: 241 HTNAGNSRAVAAGILQDV 258


>UniRef50_C3Y9W3 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3Y9W3_BRAFL
          Length = 239

 Score =  203 bits (517), Expect = 6e-51,   Method: Composition-based stats.
 Identities = 53/257 (20%), Positives = 89/257 (34%), Gaps = 52/257 (20%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I GSGL    D ++N      +   G P       +  L+LG + GV  V +    
Sbjct: 3   QIGIIGGSGLDN-PDILDNRREKHVDTPYGKP-------SDALILGDVGGVECVLLAR-- 52

Query: 87  HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
                                                ++  G +V L   I+        
Sbjct: 53  ------------------------------------EDIHPGDMVILDQFIDRTTKRATT 76

Query: 147 GLNDDRF---GERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEI 202
             + +     G     +   +    R +L  V KE      E G  V+  GP F + AE 
Sbjct: 77  FYDGNPGSPLGVCHLPMDTPFCPHTRKILIDVCKELEIRHHESGTMVTIEGPRFSSRAES 136

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD--VKLSHAQTLAAAEL 260
           +M ++ GGDV+ M+ VPEV  A+   +   AV+  T+      D    +S    L   + 
Sbjct: 137 KMFRMWGGDVINMTTVPEVALAKEAGMCYAAVAMATDYDCWRDDPGHHVSVEAVLKVFKG 196

Query: 261 SKQNFINLICGFLRKIA 277
           + +  + +    + KIA
Sbjct: 197 NAEKGVRIFKSAIPKIA 213


>UniRef50_Q1PVD3 Similar to 5'-methylthioadenosine phosphorylase n=1 Tax=Candidatus
           Kuenenia stuttgartiensis RepID=Q1PVD3_9BACT
          Length = 294

 Score =  202 bits (515), Expect = 8e-51,   Method: Composition-based stats.
 Identities = 57/265 (21%), Positives = 103/265 (38%), Gaps = 20/265 (7%)

Query: 23  DFTPRVAFILGSGLGAL--ADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
           +    +A I GS    L  +  I+        ++     +T +G +  +         ++
Sbjct: 4   NTKASLAVIGGSQAYDLLLSGCIKGKR---LGEI-----NTPYGRSQPVYFIRDANAEML 55

Query: 81  CMKGRGHFYEGRGMTIM--TDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
            +   G    G     +     I   K LG + +   +  G++      G  V + D I+
Sbjct: 56  FLSRHGEKGYGVTAPFVNYRANIYALKELGAKQIVSWSGPGAMNENYKIGEYVLIDDIID 115

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFE 197
              G           G  F      +    R  +    K  G  +T +GV+V   GP  E
Sbjct: 116 ETHGRESTFY--KHLGIGFIRQFPVFCPTLRESILHTLKFLGIGITGKGVYVCTQGPRLE 173

Query: 198 TAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAA 257
           T AEIR  ++ GGD+VGM++VPEV  A+  ++   ++  +TN AEG++       +    
Sbjct: 174 TPAEIRKYKLYGGDLVGMTLVPEVFLAKELEMCYASICYVTNYAEGIASRPFKAGELFEG 233

Query: 258 A-----ELSKQNFINLICGFLRKIA 277
                   + ++ + L    ++KIA
Sbjct: 234 LATDSDREAVRSAVALFPQIIKKIA 258


>UniRef50_C1C2B0 S-methyl-5-thioadenosine phosphorylase n=2 Tax=Caligus
           RepID=C1C2B0_9MAXI
          Length = 283

 Score =  201 bits (512), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 46/249 (18%), Positives = 93/249 (37%), Gaps = 16/249 (6%)

Query: 36  LGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH--FYEGRG 93
             +  D+ ++     Y+   G P       +  LV G + G+ V+ +    H   +    
Sbjct: 23  FYSW-DEFKHEKEEVYQTPYGEP-------SDALVSGKIDGIDVIFLSRHSHDKRFNPSE 74

Query: 94  MTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGL---ND 150
           +    + I   +  G   +    A  SL+ +      V L   I+             N 
Sbjct: 75  VNYKAN-IDALRQAGVTHILAATACESLQDDKKPEEFVILDSFIDRTTKRKQTFYDLSNP 133

Query: 151 DRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIRMMQIIG 209
           D     F  +  ++    R ++ +V  + G  +  +G  V+  GP F + AE  + +   
Sbjct: 134 DDHSCAFIPMHPSFCERSRKIVYEVGSKMGLKVHPKGTIVTIEGPRFSSKAESLVFKSWN 193

Query: 210 GDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG-LSDVKLSHAQTLAAAELSKQNFINL 268
            DV+ M+ VPEV+ A+   +  V+V+ +T+      S+  ++    +     +  N   L
Sbjct: 194 ADVINMTTVPEVVLAKEAGISYVSVAMVTDYDCWRESEESVTAQAVIEVMVKNSANVKAL 253

Query: 269 ICGFLRKIA 277
               +  +A
Sbjct: 254 SRNCISALA 262


>UniRef50_C1SHM5 Purine nucleoside phosphorylase n=1 Tax=Denitrovibrio acetiphilus
           DSM 12809 RepID=C1SHM5_9BACT
          Length = 263

 Score =  201 bits (512), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 53/249 (21%), Positives = 88/249 (35%), Gaps = 14/249 (5%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I GSGL  + +  E    I  +   G P  T         +   + +    +   G
Sbjct: 3   KLGIIGGSGLYDI-EGFEYVEEIIMQTEYGDPSDT-------YRVFSYKDMRFYFLNRHG 54

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + I  F  LG E +    A G +      G ++   D I+   G  
Sbjct: 55  RSHSVPPHKVNYRAN-IDGFSRLGIENIVSITATGGINSSYKPGDIIIPDDGIDMTSGRI 113

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIR 203
                  +           +    R +L+  A+         G +V   GP  ET  EI+
Sbjct: 114 QTFYESKQIH--HIDFTEPFCPRLRGILENSAESADVDAAVNGTYVCTNGPRMETKGEIK 171

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
                G D+VGM++ PE   AR  +L    +S ITN A G S  KL+  + +     + +
Sbjct: 172 AFDRWGADLVGMTLFPECSLARERELCYANLSVITNYAAGTSSTKLTADEVVEEMGKATE 231

Query: 264 NFINLICGF 272
               ++   
Sbjct: 232 KLKGIVSML 240


>UniRef50_A4AL37 5'-methylthioadenosine phosphorylase n=3 Tax=Actinobacteria (class)
           RepID=A4AL37_9ACTN
          Length = 267

 Score =  200 bits (510), Expect = 3e-50,   Method: Composition-based stats.
 Identities = 60/257 (23%), Positives = 102/257 (39%), Gaps = 17/257 (6%)

Query: 22  PDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVC 81
                 +A I GSGL +L          + +      + T +G    +  G L G  V  
Sbjct: 2   TPLRTSLAVIGGSGLYSL---------FAPDSAKHQRIETPYG-PTTVSFGELSGRMVAF 51

Query: 82  MKGRG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINT 139
           +   G  H      +    + I     +G   +  T A G++ P+   GSLV    +I+ 
Sbjct: 52  IPRHGSGHSVAPHLINYRAN-IWALGSIGVRAIVSTAAVGAVHPDFPVGSLVLPDQYIDR 110

Query: 140 MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETA 199
             G        DR   +  + ++ +     AL   VA      + +G  V   GP F T 
Sbjct: 111 TQGRAATFY--DRESVQHLASSDPFCPSLHALA--VAATGDEAIAQGTVVVIQGPRFSTR 166

Query: 200 AEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAE 259
           AE +  + +GG +V M++ PEV  A   ++  + V+ IT+    +SD +LS     A  +
Sbjct: 167 AESQWFRSMGGHLVNMTLYPEVPLASELNIGTINVAYITDNDATVSDEQLSAELVFARLK 226

Query: 260 LSKQNFINLICGFLRKI 276
            ++   I +I   +  I
Sbjct: 227 EAQPRIIRVIEKIIATI 243


>UniRef50_B8KGW0 Purine phosphorylase, family 2 n=1 Tax=gamma proteobacterium NOR5-3
           RepID=B8KGW0_9GAMM
          Length = 249

 Score =  200 bits (508), Expect = 5e-50,   Method: Composition-based stats.
 Identities = 53/252 (21%), Positives = 91/252 (36%), Gaps = 13/252 (5%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +  I G+GL AL   +E   + + +   G P   +         G   G  +  +   G 
Sbjct: 3   LGLIGGTGLNALP-GLEVVASHAVDTPFGQPSMAIE-------EGVYAGHKLFFLHRHGG 54

Query: 88  F---YEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
                    +    + +   + LG   +   NA G++   +  G LV     I+   G  
Sbjct: 55  RAQPIPPHLVNYRAN-VWALRELGVTRILAANAVGAISAGMAPGKLVVPHQLIDYTWGRE 113

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIR 203
               +              YD   R+ +   A+  G P ++  V     GP  ETAAE++
Sbjct: 114 HSFDDGSSGELLHVDFTQPYDGVLRSEIISAAESAGVPHSDTAVLGVVQGPRLETAAEVQ 173

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
                G D++GM+ +PE   AR   +   A+  + N A G+    +S             
Sbjct: 174 RFAADGCDLLGMTGMPEAALARELGIPYAAICMVVNAAAGVGAEPISMEAIRNTLLEETA 233

Query: 264 NFINLICGFLRK 275
            F  L+  F+R+
Sbjct: 234 LFGALVGAFVRR 245


>UniRef50_Q07938 Multicopy enhancer of UAS2 n=12 Tax=Saccharomycetaceae
           RepID=MEU1_YEAST
          Length = 337

 Score =  200 bits (508), Expect = 6e-50,   Method: Composition-based stats.
 Identities = 54/265 (20%), Positives = 93/265 (35%), Gaps = 19/265 (7%)

Query: 27  RVAFILGSGLGALADQIENAVAISYE-KLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
            +  I G+GL  L D +E    +       G   S V        +G      V  +   
Sbjct: 34  DLGIIGGTGLYNL-DCLEPIALLPPMVTPWGTTSSPVTISQ---FVGTNSHFHVAFIARH 89

Query: 86  G--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           G  H Y    +    + +   K L C+ +   +A GSL+P +     V  +  I+   G 
Sbjct: 90  GINHEYPPTKVPFRAN-MAALKNLNCKAVLSFSAVGSLQPHIKPRDFVLPQQIIDRTKGI 148

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQK-------VAKEEGFPLT---EGVFVSYPG 193
                 +D            +  ++   + +          EE   L    +   V   G
Sbjct: 149 RHSSYFNDEGLVGHVGFGQPFSQKFAEYIYQFKNEITNPESEEPCHLHYDKDMTVVCMEG 208

Query: 194 PNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD-VKLSHA 252
           P F T AE +M ++ GG V+ MSV+PE   AR C+L    +   T+      +   ++  
Sbjct: 209 PQFSTRAESKMYRMFGGHVINMSVIPEAKLARECELPYQMICMSTDYDAWRDEAEPVTVE 268

Query: 253 QTLAAAELSKQNFINLICGFLRKIA 277
             +     + +N   L    +  +A
Sbjct: 269 TVIGNLTNNGRNANILASKIIVSMA 293


>UniRef50_B8NP67 5'-methylthioadenosine phosphorylase (Meu1), putative n=1
           Tax=Aspergillus flavus NRRL3357 RepID=B8NP67_ASPFN
          Length = 365

 Score =  199 bits (507), Expect = 7e-50,   Method: Composition-based stats.
 Identities = 50/283 (17%), Positives = 90/283 (31%), Gaps = 38/283 (13%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHG-HAGELVLGHLQGVPVVCMKGR 85
           R+A I G+GL  L        +++     G P S +   H           V V  +   
Sbjct: 44  RIAVIGGTGLRELP-GFTQVASLNISTPWGTPSSPITILHHQCSHNKQ--TVAVAFLSRH 100

Query: 86  G--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG- 142
           G  H      +    + I   + +G   +   +A GSL+ E+     V     I+   G 
Sbjct: 101 GLHHQIAPHEVPARAN-IAALRSIGVRTIIAFSAVGSLQEEIKPRDFVIPDQVIDRTKGI 159

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE---GFPLT-EGVFVSY------- 191
            P                 + +D     +++         G  L   G  V         
Sbjct: 160 RPFTFFEGG--VVAHVPFGDPFDEGVAKVVRACGHSLEGEGVVLHDRGTLVCMGMLFAQS 217

Query: 192 ----------------PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVS 235
                            GP F T AE ++ +  GG V+ MS +PE   AR  ++    + 
Sbjct: 218 DRSNRYQYNRLLTSFPEGPQFSTRAESKLYRSWGGSVINMSCLPEAKLAREAEIAYQMIC 277

Query: 236 AITNMAEGLS-DVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
             T+          ++    +   + + +N  + +   L ++A
Sbjct: 278 MSTDYDCWHEATADVTVEMVMGNMKANAENAKHFVTAVLDELA 320


>UniRef50_A0YHC5 Methylthioadenosine phosphorylase n=1 Tax=marine gamma
           proteobacterium HTCC2143 RepID=A0YHC5_9GAMM
          Length = 241

 Score =  199 bits (506), Expect = 9e-50,   Method: Composition-based stats.
 Identities = 53/250 (21%), Positives = 94/250 (37%), Gaps = 16/250 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG-HLQGVPVVCMKGRG 86
           +  I G+GL +          +           T +G     ++G  ++G+PV  +   G
Sbjct: 2   IGIIGGTGLSSFHQGRSVGDRL-----------TPYGETSAAIIGSEIEGIPVCFLARHG 50

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H      +    + I  FK LG   L   NA G +  E+ AGSLV     ++   G  
Sbjct: 51  DPHRIPPHKVNYRAN-IWAFKELGVSKLVAVNAVGGITSEMPAGSLVIPDQIVDYTYGRD 109

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIR 203
               + +         +  + +  R L+   A      + +G       GP  E+AAEI 
Sbjct: 110 HTFYDGNNNELEHIDFSFPFASGLRQLIVAAAAASNINIIDGATLGVTQGPRLESAAEIN 169

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
            M+  G ++VGM+ +PE   AR   +   ++  + N A G     ++  Q     +    
Sbjct: 170 RMESDGCELVGMTAMPEAALARELSIDYASICLVVNPAAGRGHSVITMDQINDVIQFGMT 229

Query: 264 NFINLICGFL 273
           +   L+   +
Sbjct: 230 DVRRLLMAAI 239


>UniRef50_C5C002 Methylthioadenosine phosphorylase n=37 Tax=Actinomycetales
           RepID=C5C002_BEUC1
          Length = 301

 Score =  195 bits (497), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 55/253 (21%), Positives = 87/253 (34%), Gaps = 16/253 (6%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +  I GSGL  L   + +   +      G P           VLG L G  V  +   G 
Sbjct: 19  IGVIGGSGLYEL---LASPAPVDVTTPFGTPSEAP-------VLGELGGRQVAFLPRHGA 68

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H +    +    + +   + LG   +    A G+L P++  G++V     I+   G   
Sbjct: 69  DHRFPPHRVPYRAN-LWALRALGVRQVVTVGAVGALVPDLARGAVVVPDQIIDLTSGREH 127

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIRM 204
               D          A+ Y    RA            + +G   V   GP F T AE R 
Sbjct: 128 TVF-DGVGTVVHVPFADPYCPRGRAAALSALGGRALDVRDGGTLVVINGPRFSTRAESRR 186

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEG-LSDVKLSHAQTLAAAELSKQ 263
               GG VVGM+ +PE   AR   +    ++ +T+   G      ++HA  L        
Sbjct: 187 NVAAGGTVVGMTGMPEAALARELAMCCTNLALVTDADAGVDGGESVTHAAVLEEFARHLA 246

Query: 264 NFINLICGFLRKI 276
                +   +  +
Sbjct: 247 VLRASLTDVVTAL 259


>UniRef50_Q2S4Q1 Purine nucleoside phosphorylase I, inosine and guanosine-specific
           n=1 Tax=Salinibacter ruber DSM 13855 RepID=Q2S4Q1_SALRD
          Length = 285

 Score =  195 bits (496), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 77/250 (30%), Positives = 114/250 (45%), Gaps = 7/250 (2%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           +P VA +    L  +         I Y  LP +P S      G L +G L G  VV +  
Sbjct: 35  SPTVAIVRDVELDDVLQAGTVEHTIPYANLPHYPAS-----DGTLTIGTLGGTQVVELDQ 89

Query: 85  RGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H Y+G     ++  +R     G + L     AGS+  +   G L+ L DHIN     P
Sbjct: 90  AFHLYDGHTPREVSFPVRMLATAGIDSLLLAAPAGSVTAQADRGDLMLLTDHINFQGQNP 149

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRM 204
           +VG N + +G RF  +   YDA  R      A+  G PL +G+++   GP+ ET AE RM
Sbjct: 150 LVGPNVEEWGPRFPDMTAPYDATLRQRASDAARSAGVPLRQGIYMGLLGPHHETTAEHRM 209

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
              +G DVVG  VVPEV++ARH  + V+A++ +T       D   S      + + S+  
Sbjct: 210 AHRLGADVVGTGVVPEVLAARHMGVHVMALTLLTAQHLAEDDGAPSSE--GPSLQTSRSQ 267

Query: 265 FINLICGFLR 274
              L+   + 
Sbjct: 268 LHRLLVATVA 277


>UniRef50_C2KQL7 Possible purine-nucleoside phosphorylase n=2 Tax=Mobiluncus
           mulieris RepID=C2KQL7_9ACTO
          Length = 279

 Score =  194 bits (494), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 68/270 (25%), Positives = 121/270 (44%), Gaps = 21/270 (7%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGL-GALADQIENAVAISYEKLPGFPVSTVHGHAGELV 70
             + +I+         V  +LGSGL   + +  +N V +  ++L G  + +  GH  ++V
Sbjct: 25  AAVQLIQERTQRENHDVLVVLGSGLHDTVCNLGKNPVELPLKELLGAKIPSAQGHGTQIV 84

Query: 71  LGHLQG----VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVG 126
              ++     V ++   GR H YEG     +    +   + G +  F TNA G L+P   
Sbjct: 85  SVQIETEAKTVNILVCTGRIHLYEGHTPADLCFVPQVAAMTGIQAAFLTNAGGCLQP-WE 143

Query: 127 AGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG 186
            G ++A++DHIN    +P  G         F  ++  +D++  A ++K A         G
Sbjct: 144 LGDVMAIRDHINFSGASPFTGP-------VFVDISQVWDSDLTAAIKKHASRS------G 190

Query: 187 VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD 246
           V+    GP ++T AE  MM+  G D+VGMS V E I+     ++V  VS  +++    S 
Sbjct: 191 VYAISRGPEYQTLAESIMMRNNGIDMVGMSTVLEAIALHQLGVRVCGVSVTSDLT--FSS 248

Query: 247 VKLSHAQTLAAAELSKQNFINLICGFLRKI 276
              +H++ L A   +     N +   +  +
Sbjct: 249 TPTTHSEVLHAVRSAIPCVQNCLYEVINAL 278


>UniRef50_B5ICA6 Phosphorylases family 2 n=2 Tax=Aciduliprofundum boonei T469
           RepID=B5ICA6_9EURY
          Length = 224

 Score =  194 bits (493), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 55/246 (22%), Positives = 98/246 (39%), Gaps = 28/246 (11%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +  I GSGL    + IE    I         + T +G     +     G     +   G+
Sbjct: 2   IGIIGGSGLYDGIEGIEGKEKI---------IRTEYGDVKVFI-----GDNFAFVSRHGN 47

Query: 88  FY-EGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMV 146
                  +    + I  F+ L  + +   +  GSL+  +  GS +   + ++      + 
Sbjct: 48  PPKPPHRVNYHAN-IMAFRELNVKNIVAISTVGSLKDNIKPGSFLLPSNLLDFT--NRVW 104

Query: 147 GLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQ 206
             +D+       ++   +  E R    K+ ++   PL  G + +  GP FETAAE  M++
Sbjct: 105 TYHDNE--PYHVNMYEPFCKELR---VKINEKLSIPL-GGTYATMKGPQFETAAEANMLR 158

Query: 207 IIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFI 266
           I+G D+VGM+V PE   A+  +L    +  + N  +G    K SH + L   +   +   
Sbjct: 159 ILGADIVGMTVAPEAKLAKELNLCYQPICIVVNYVDG----KTSHKENLKVMKELNEQLK 214

Query: 267 NLICGF 272
            LI   
Sbjct: 215 KLIQEL 220


>UniRef50_C9ZU87 Methylthioadenosine phosphorylase, putative n=8
           Tax=Trypanosomatidae RepID=C9ZU87_TRYBG
          Length = 309

 Score =  194 bits (493), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 52/265 (19%), Positives = 94/265 (35%), Gaps = 26/265 (9%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +  I GSG   L + ++N    +     G P       +G + +  + GV    +   G+
Sbjct: 13  IGVIGGSGTYNL-NAMQNVKKYTIPTPYGMP-------SGSISVATVSGVLCAFIPRHGY 64

Query: 88  FYEGRG--MTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            +E     +    + I   KLLG + L   NA GSL  E   G +V +   I+   G   
Sbjct: 65  SHEFTPDEVNYRAN-IYALKLLGVKYLIGVNAVGSLDAEYQPGDMVLVDQLIDRTTGRRT 123

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE------------GFPLTEG-VFVSYP 192
                          A    A +R L      +              + L  G   V+  
Sbjct: 124 TFF--GEGIVAHVDYAYPLSANFRKLAHDTLTKAMGKLTTAVSGGKPWKLHNGATLVTMS 181

Query: 193 GPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHA 252
           GP F T AE  + + + G ++GM+   E   AR  ++  + V+A+T+M        +   
Sbjct: 182 GPQFSTRAESLINKSLNGHLIGMTTSTESKLAREAEMAYLVVAAVTDMDAWSDAPHVDAE 241

Query: 253 QTLAAAELSKQNFINLICGFLRKIA 277
                   + +    ++   +  ++
Sbjct: 242 SVRKVMAANVEKVQLIVVELIAAVS 266


>UniRef50_Q7TP15 Cc1-6 n=9 Tax=Coelomata RepID=Q7TP15_RAT
          Length = 391

 Score =  193 bits (490), Expect = 8e-48,   Method: Composition-based stats.
 Identities = 48/302 (15%), Positives = 95/302 (31%), Gaps = 60/302 (19%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I G+GL    + +E       +   G P       +  L+LG ++ V  V +    
Sbjct: 48  KIGIIGGTGLDD-PEILEGRTEKYVDTPFGKP-------SDALILGKIKNVDCVLLASMY 99

Query: 87  --------------------HFYEG-------RGMTIMTD---AIRTFKLLGCELLFCTN 116
                               H                +      +R    + CE  F  +
Sbjct: 100 VLDRMCEFLLLPFCVQLNSLHEIPPGSSCHTSYLFAFVARWERRVRWLARVLCERAFVPS 159

Query: 117 AAGSLRPEVGAGSLVALKDHI-----------------NTMPGTPMVGLNDDRF---GER 156
           +A +            +                           P    +       G  
Sbjct: 160 SASTSVQWKETKHSKEITQRSKASRFSTTVQQQAIREECQTSLRPQTFYDGSHCSARGVC 219

Query: 157 FFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIRMMQIIGGDVVGM 215
              +A  +  + R +L ++AK+ G     +G  V+  GP F + AE  + +  G DV+ M
Sbjct: 220 HIPMAEPFCPKTREVLIEMAKKLGLRCHSKGTIVTIEGPRFSSRAESFIFRTWGADVINM 279

Query: 216 SVVPEVISARHCDLKVVAVSAITNMAEGLS-DVKLSHAQTLAAAELSKQNFINLICGFLR 274
           + VPEV+ A+   L   +++  T+       +  +S    L   + +     +L+   + 
Sbjct: 280 TTVPEVVLAKEAGLCYASIAMATDYDCWKEHEEAVSVDGVLKTMKENANKAKSLLLTTIP 339

Query: 275 KI 276
           +I
Sbjct: 340 QI 341


>UniRef50_Q1CZV1 Phosphorylase, family 2 n=5 Tax=Myxococcaceae RepID=Q1CZV1_MYXXD
          Length = 295

 Score =  192 bits (488), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 62/258 (24%), Positives = 90/258 (34%), Gaps = 19/258 (7%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           RV  I   GL           +   E   G        HAG +V   L GV V  +   G
Sbjct: 4   RVGIIGSPGLAQALGIPGKGESHILETPFGP-------HAGPIVTTELDGVSVAYVARHG 56

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H Y         + +   K+LG   +  T   GSLR  +    L      I+     P
Sbjct: 57  TGHVYNATRAPYRAN-MYALKVLGVTHVLATGTVGSLREHIHPLHLALPDQVIDRTYRRP 115

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIR 203
               +D         L N +    R +L+      G  +  E  +V   GP+  T AE  
Sbjct: 116 CTFYDD---VAVHVDLGNPFCGTLRQVLEHARDPLGPTVHAEATYVCIEGPSLSTRAESM 172

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK-LSHAQTLAAAELSK 262
           + +  GGD+VGM+ +PE   AR  +L    V+  T+            H   LA    ++
Sbjct: 173 LYRTWGGDLVGMTGMPEARLAREAELHYAMVALPTDYDSWQPRAPGQEHDDLLAQVSHNR 232

Query: 263 QNFI----NLICGFLRKI 276
           +        LI   L +I
Sbjct: 233 KAVTASGAALIRRALPRI 250


>UniRef50_B8P408 Predicted protein n=2 Tax=Agaricomycetes RepID=B8P408_POSPM
          Length = 329

 Score =  189 bits (481), Expect = 7e-47,   Method: Composition-based stats.
 Identities = 56/277 (20%), Positives = 100/277 (36%), Gaps = 36/277 (12%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +  I GSGL  L D +     ++ E   GFP S +   A         G  V  +   G 
Sbjct: 16  IGVIGGSGLYHL-DNLTFIKHVNPETPWGFPSSPITICALP------SGTRVAFLARHGT 68

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
            H      +    + I   K LG   +   +A GSLR ++  G +V     I+   G   
Sbjct: 69  GHSIAPSAVPARAN-IAALKALGVRAVLAFSAVGSLREDIRPGDVVLPAQIIDRTKGVRP 127

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQ---------KVAK--------EEGFPLT-EGV 187
               +        +  + + A     L+         + A+        + G  +  +  
Sbjct: 128 ASFFEGTGVVAHAAFGDPFAARLVRWLEGRVRAVLAEEAARVQRETGRPDAGPRVHADKC 187

Query: 188 FVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDL-------KVVAVSAITNM 240
            V   GP F T AE +M +  GGD++ MSV+PE   AR  +L           ++  T+ 
Sbjct: 188 VVCMEGPQFSTRAESQMYRAWGGDIINMSVLPEAKLAREAELLPPPSLSVYALIATATDY 247

Query: 241 AEGLS-DVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
                 +  ++ A+     + + +   ++    L ++
Sbjct: 248 DSWRPHEDAVTAAEVFKTLQENARISRHVAATVLEEL 284


>UniRef50_A7BPC6 Purine phosphorylase, family 2 n=2 Tax=Gammaproteobacteria
           RepID=A7BPC6_9GAMM
          Length = 181

 Score =  188 bits (477), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 48/182 (26%), Positives = 76/182 (41%), Gaps = 2/182 (1%)

Query: 94  MTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRF 153
           M    + I + K LG + +    A G + PE+    LV     I+           D+  
Sbjct: 1   MNYRAN-IGSIKALGIKTVIAVAAVGGIHPEMRPKDLVIPHQMIDYTYSREQTFFADEFN 59

Query: 154 GERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIRMMQIIGGDV 212
                     Y  E R  L K A+   F +  +GV+ +  GP  ETAAEI  M+  G D+
Sbjct: 60  HVTHIDFTQPYCDELREQLLKAAESFDFKVHSQGVYGATQGPRLETAAEINRMEREGCDI 119

Query: 213 VGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGF 272
           VGM+ +PE   AR  +L     + + N A G    +++  +  A  +   +N   L+   
Sbjct: 120 VGMTGMPEAALARELELCYATCAVVANPAAGRGSAQITMTEIEATLKQGIENVRQLLGVV 179

Query: 273 LR 274
           +R
Sbjct: 180 IR 181


>UniRef50_C3ZRU9 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3ZRU9_BRAFL
          Length = 374

 Score =  186 bits (472), Expect = 7e-46,   Method: Composition-based stats.
 Identities = 68/209 (32%), Positives = 110/209 (52%), Gaps = 11/209 (5%)

Query: 77  VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS--LRPEVGAGSLVALK 134
            PV   K  G       +  +   +R FKL+G         A    L      G ++ + 
Sbjct: 168 RPVRVFKVMG--ILSAPLPQVALPVRVFKLMGILSAPLPQVALPVALPAVFNDGYIMLMT 225

Query: 135 DHINT---MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFV 189
            HI+        P+ G N+DRFG RF ++++AY++E R + + + KE GF   + EGV+V
Sbjct: 226 PHISMPGLAGDNPLKGHNEDRFGPRFPAVSDAYNSELRQMARDIGKELGFESFMQEGVYV 285

Query: 190 SYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK- 248
              GP++ET AE ++++++GGD VGMS VPEVI+ARHC ++V  +S +TNM     D K 
Sbjct: 286 QVGGPSYETIAECKLLRMLGGDAVGMSTVPEVIAARHCGIRVFGMSLVTNMVVMDYDTKG 345

Query: 249 -LSHAQTLAAAELSKQNFINLICGFLRKI 276
            ++H + L       Q+   L+   + ++
Sbjct: 346 TVNHEEVLETGRRRAQDMQKLVSKMIGQL 374



 Score = 75.3 bits (184), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 36/110 (32%), Positives = 49/110 (44%), Gaps = 4/110 (3%)

Query: 14  IDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH 73
            D I T K    P++A I GSGLG LAD +E+  AI Y ++P FP ST  G+     L  
Sbjct: 15  SDFILT-KTKHRPKIAVICGSGLGGLADIVEDQNAIDYSEIPNFPRSTADGYTQSAPLPQ 73

Query: 74  LQGVPVVCMKGRGHFYEGRG--MTIMTDAIRTFKLLGCELLFCTNAAGSL 121
           +  +PV   K  G            +   +R FKL+G         A  +
Sbjct: 74  VA-LPVRVFKLMGILSAPLPQVALPVALPVRVFKLMGILSAPLPQVALPV 122


>UniRef50_O28486 Methylthioadenosine phosphorylase (MtaP) n=1 Tax=Archaeoglobus
           fulgidus RepID=O28486_ARCFU
          Length = 243

 Score =  186 bits (472), Expect = 8e-46,   Method: Composition-based stats.
 Identities = 56/253 (22%), Positives = 105/253 (41%), Gaps = 23/253 (9%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +  I G+        +E  V    E+     + T +G A E+ +G + G+ V  ++  G 
Sbjct: 2   IGIIGGT------HILEIKVLKDVEET---RIETPYGTA-EIDVGRVDGIDVAIIQRHGK 51

Query: 88  FY--EGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
                   +    +     K LG + +    + G+LR E    SL+   D+I+   G  +
Sbjct: 52  RKDKPPHRINHAAN-FYALKSLGVKYVIGMGSVGALREEYSLPSLIIPHDYIDFFSGVTI 110

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG--FPLTEGVFVSYPGPNFETAAEIR 203
              ND             +D   R +L +VA++      + +GV+    GP  ET AEI 
Sbjct: 111 --YNDSLVHV-----TPGFDEYLREVLVEVARKISSFPVIDKGVYFQTRGPRLETKAEIA 163

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
           M++    D VGM+   E   AR   L    V  + N A G+ +  + + + +  A+ + +
Sbjct: 164 MIKSF-ADCVGMTAGSEATIARELGLSYAIVCTMDNYAHGIKNQSIDYREIVEKAKENAR 222

Query: 264 NFINLICGFLRKI 276
             + ++   ++K+
Sbjct: 223 ECLKIVEEAVKKV 235


>UniRef50_A0B8I0 Methylthioadenosine phosphorylase n=1 Tax=Methanosaeta thermophila
           PT RepID=A0B8I0_METTP
          Length = 245

 Score =  185 bits (469), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 54/219 (24%), Positives = 88/219 (40%), Gaps = 12/219 (5%)

Query: 59  VSTVHGHAGELVLGHLQGVPVVCMKGRGHFY-EGRGMTIMTDAIRTFKLLGCELLFCTNA 117
           ++T +G+   +    + G  VV +   G  +     +      I   +  G   +   N 
Sbjct: 21  IATPYGNVRAISS-RISGRDVVFISRHGDDHLPPYRVNYRAI-ICAAESTGAGRIIAINT 78

Query: 118 AGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAK 177
            GS+      GS V   D I            D         ++  Y  E R +L +  +
Sbjct: 79  VGSMIS--PPGSFVIPNDFIEFTKFRVPTFYED---RAVHVDMSEPYCPEIRKVLMESCR 133

Query: 178 EEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAI 237
            EG    EGV+V   GP+FET A+I+M++  G DVVGM+  PEV+ AR   L   ++   
Sbjct: 134 AEGHEPYEGVYVCTEGPHFETHAQIKMLRSFG-DVVGMTGYPEVVLARERGLCYASICLA 192

Query: 238 TNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI 276
           TN A    + +    Q ++    S  +   +I   +  I
Sbjct: 193 TNKA---GEGQFDLRQIVSVERKSMSDLARIIERAVSMI 228


>UniRef50_A6GFX4 Purine nucleoside phosphorylase n=1 Tax=Plesiocystis pacifica SIR-1
           RepID=A6GFX4_9DELT
          Length = 278

 Score =  184 bits (468), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 77/273 (28%), Positives = 118/273 (43%), Gaps = 26/273 (9%)

Query: 13  CIDIIKTYKPDFTP-RVAFILGSGLGA-LADQIENAVAISYEK-LP----GFPVSTVHGH 65
           C   ++   P+  P     I GSG+G  L  + E+A+ +S  + +P    G P  +V GH
Sbjct: 14  CEAALRERLPEQGPVDWMIIGGSGIGKPLVAEGEHALGLSIRERIPLAELGLPAPSVAGH 73

Query: 66  AGELVLGHLQG-----VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
             ELV G L       V V    GR H YEG    + +  +     +G   +  T+A G 
Sbjct: 74  GSELVFGELAREGADPVQVCVQTGRIHPYEGHSAALASAPLGAVLSIGARQVLLTSAVGG 133

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           +  ++  G +V+ +D  N    T + G         F   +  YD E RA LQ+      
Sbjct: 134 VNTQLRVGEIVSYRDQFNLFGPTSLRG-------AAFIDCSRLYDPELRARLQQ----LD 182

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
             L E V+    GP +E+ AE+  ++ +G DVVGMS   E I A    +    +  +TN 
Sbjct: 183 GSLREVVYGHARGPQYESPAEVAALRTLGCDVVGMSTTYEAILAAAHGVPTCGLGVVTNA 242

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFL 273
           A       LSH +    +  ++    NL+ G L
Sbjct: 243 A---GAEALSHVEVQEESGKARTRLANLVRGLL 272


>UniRef50_UPI00016C3D31 inosine guanosine and xanthosine phosphorylase family protein n=2
           Tax=Gemmata obscuriglobus UQM 2246 RepID=UPI00016C3D31
          Length = 261

 Score =  182 bits (462), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 75/226 (33%), Positives = 113/226 (50%), Gaps = 6/226 (2%)

Query: 49  ISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLG 108
           + +  +PG    +VHGH G L +G   GVP + ++GR HFYEG    ++T  +RT   LG
Sbjct: 39  VPFGAVPGLVPPSVHGHGGTLAVGEWGGVPALLVRGRVHFYEGHPWEVVTGTVRTAAELG 98

Query: 109 CELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEY 168
              L  TNAAG + P +  G+L+A++ H+  +      GL       R       Y A  
Sbjct: 99  ARRLVLTNAAGGINPALSPGALMAIRGHLKLLGPAAWRGLAAGDGSVR------PYAARL 152

Query: 169 RALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCD 228
             +++   +  G  L  G++ +  GP++ET AEIR +   G D VGMS   E  +A    
Sbjct: 153 IEVMRAHERAGGRELLAGLYAALTGPSYETPAEIRALAACGADAVGMSTALEAEAAAARG 212

Query: 229 LKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLR 274
           L+V A+S +TN A G+    L HA+ L  A L+      L+   +R
Sbjct: 213 LEVAAISCVTNKAAGIGGTALDHAEVLTNAALAVDRLGALLGALIR 258


>UniRef50_D0JB48 Purine nucleoside phosphorylase n=2 Tax=Blattabacterium
           RepID=D0JB48_BLASB
          Length = 268

 Score =  181 bits (460), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 79/268 (29%), Positives = 131/268 (48%), Gaps = 22/268 (8%)

Query: 15  DIIKTYKPDFTPRVAFIL-GSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH 73
             I   K    P    +L GS    L ++I+N + ISYE++P F    ++G   + + G 
Sbjct: 12  QYI-QNKIKEKPDFGILLLGSQFDKLIEEIQNPICISYEEIPLFSKKKLYG---KFLFGQ 67

Query: 74  LQGVPVVCMKGRGHFYEGRGMTIMT--DAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLV 131
           ++G  VV +       E       T    I   K +G + L   N +G + P    G ++
Sbjct: 68  IEGKNVVFL------IEPFSEENRTNYFTIVLCKHIGIDKLILINISGGVNPNYKMGDVM 121

Query: 132 ALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSY 191
            +KDHIN  P +P +   +D    RFF +   YD +   + + +A      + +GV+V++
Sbjct: 122 LVKDHINFFPESPNI---NDLIKNRFFEITEPYDQKMLEIAENIAMNHNIIIQKGVYVAF 178

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKL-- 249
           P  N++T AE  M++ +GGD VGM++V +VI+AR  +L+V A+S I  M  GLS+ K+  
Sbjct: 179 PYSNYKTYAEYAMIRSMGGDSVGMNIVTDVITARCMNLRVFAISIIV-MGMGLSEPKIQK 237

Query: 250 ---SHAQTLAAAELSKQNFINLICGFLR 274
              S        E S    I ++  F++
Sbjct: 238 NADSRNTFFQETEKSISLLILIVKEFIK 265


>UniRef50_Q0SDK3 Probable S-methyl-5-thioadenosine phosphorylase n=2 Tax=Rhodococcus
           RepID=Q0SDK3_RHOSR
          Length = 260

 Score =  181 bits (460), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 55/261 (21%), Positives = 96/261 (36%), Gaps = 21/261 (8%)

Query: 22  PDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHG-HAGELVLGHLQGVPVV 80
           PD  P V  +   G   L D  E              + T +G  +  +VLG   G  + 
Sbjct: 2   PDTQPTVGVLGTWGYHGLLDDAEQVD-----------IDTPYGPTSDSIVLGSSGGRRLA 50

Query: 81  CMK--GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
            +   GR        +    + I     LG   +     +GSLRP +G GS+V     ++
Sbjct: 51  YLTRTGRHRNIPPHRINARAN-IWALHSLGVRTILAPTPSGSLRPAIGVGSVVVPDQLVD 109

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFE 197
               T     +DD       S A+ + A  R  +    +  G+ + +G V V+  GP F 
Sbjct: 110 RTGRTDDTFHDDD----VHISFADPFCAHGRRAVVSTLRRNGWVVNDGGVMVAIRGPRFS 165

Query: 198 TAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAE-GLSDVKLSHAQTLA 256
           T AE R     G D++ M+  PE   AR   +    ++ +T+      +   ++      
Sbjct: 166 TRAESRWYAAQGWDLISMTPYPEAALARELGMSYTCIALVTDHDVISDTPWPVTQDLVRE 225

Query: 257 AAELSKQNFINLICGFLRKIA 277
             + + +     +     ++A
Sbjct: 226 GLDANTKRLREALLQVAIELA 246


>UniRef50_B0TI52 Purine nucleoside phosphorylase n=8 Tax=Clostridia
           RepID=B0TI52_HELMI
          Length = 304

 Score =  180 bits (457), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 55/272 (20%), Positives = 94/272 (34%), Gaps = 15/272 (5%)

Query: 7   SHNPLFCIDIIKTYKPDFTPRVAFILGSGLGAL--ADQIENAVAISYEKLPGFPVSTVHG 64
           S  P+  + ++ +      P  A I GS   +L   + +        E  PG+   T  G
Sbjct: 11  SQMPMEVMAMLSSASIPAAP-FAIIGGSSTNSLRFPEALNVPGLTVLETYPGW--ETPFG 67

Query: 65  HAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPE 124
            +   V   L+G   +     G     +           F+  G + +      G++   
Sbjct: 68  PSPAFVYFELKGRRALTCVMHGWRPGVKRADASRQIFWVFQQAGVKQILSEGGVGAINEL 127

Query: 125 VGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE---GF 181
           +    LV   D+I+          + D        +   +    R      ++     G 
Sbjct: 128 LRPRDLVIPHDYIDFSMR-----KDVDLGTPTLCIMRQPFCPLLRRAFIDASEALPGKGR 182

Query: 182 PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMA 241
                 +V   G +FE+ AE+R  ++ GGDV+G SV PEV  AR        +  + N A
Sbjct: 183 VFDRSNYVVTDGRHFESPAEVRFFRMAGGDVIGQSVAPEVYLAREIGACYARLELVVNYA 242

Query: 242 EGLSDVKLSHAQTLAAA-ELSKQNFINLICGF 272
           EG+     SH +      E S+     L+   
Sbjct: 243 EGVITDW-SHQELKDIFYEESEPAGRRLLMAL 273


>UniRef50_A0L8V4 Methylthioadenosine phosphorylase n=1 Tax=Magnetococcus sp. MC-1
           RepID=A0L8V4_MAGSM
          Length = 241

 Score =  180 bits (457), Expect = 5e-44,   Method: Composition-based stats.
 Identities = 60/256 (23%), Positives = 101/256 (39%), Gaps = 28/256 (10%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++A I G+ L           +  +     +P++T  G         L+   +V ++  G
Sbjct: 6   KIAVIGGTSL---------LESHLFSGAKEYPIATPFGKVTL-----LEKQGLVFLQRHG 51

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
             H+     +    + +   K  G   L    + GS++ E   G+ +   D +       
Sbjct: 52  MDHYTPPHLINHKAN-LAGLKEYGITHLLAIGSVGSMKLEHPPGTFLIPDDFLGL--DVC 108

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVA---KEEGFPLTEGVFVSYPGPNFETAAE 201
                D R           +D  +R  +       +  G P+  GV+    GP FET AE
Sbjct: 109 PTFFEDARG-----HQVPGFDPAWRQQILAAWPPSESFGAPVDGGVYWQTRGPRFETQAE 163

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELS 261
           IRM Q    DVVGM+V  E I AR  DL   A+  + N A G+SD  L++A        +
Sbjct: 164 IRMYQAF-TDVVGMTVASECILARELDLAYAAICIVDNYANGISDEPLTYAAFKQKVAEN 222

Query: 262 KQNFINLICGFLRKIA 277
           +    +L+   L +++
Sbjct: 223 EARLGSLLHILLERLS 238


>UniRef50_C1YKP8 Inosine guanosine and xanthosine phosphorylase family protein n=1
           Tax=Nocardiopsis dassonvillei subsp. dassonvillei DSM
           43111 RepID=C1YKP8_NOCDA
          Length = 274

 Score =  177 bits (450), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 68/267 (25%), Positives = 114/267 (42%), Gaps = 12/267 (4%)

Query: 10  PLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENA-VAISYEKLPGFPVSTVHGHAGE 68
                  + +     +     +LGSG     D + +  + +    LPGF      GH+G+
Sbjct: 18  AADAARELLSRTGADSFDALVVLGSGWAGAVDTLGSYDIELDATDLPGFHEPAAEGHSGK 77

Query: 69  LVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAG 128
           +    +    V+   GR H YEGR    +  A+RT    G      T AAGSLR +   G
Sbjct: 78  IRSMWVGDKRVIVFMGRVHLYEGRDPLEVVHAVRTGVAAGARTAVLTGAAGSLRTDFATG 137

Query: 129 SLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVF 188
             V ++DHIN    +P+VG         F  L++AY    R  +Q+        + EGV+
Sbjct: 138 QPVVVRDHINLTARSPLVGP-------SFVDLSSAYSPRLRRAVQEA----DASVPEGVY 186

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVK 248
           V   GP  +T AE++++   G D+VG S+  E ++A     +V+ ++ ++N A G     
Sbjct: 187 VCTTGPQTQTPAELKVLHQAGADLVGHSIALEAVAAVEAGAEVLGLAVVSNDAVGAVFEP 246

Query: 249 LSHAQTLAAAELSKQNFINLICGFLRK 275
               + L       +    L+   + +
Sbjct: 247 FEAERALDVVTQRARRLGELLNRVIGQ 273


>UniRef50_Q11FN7 Methylthioadenosine phosphorylase n=1 Tax=Chelativorans sp. BNC1
           RepID=Q11FN7_MESSB
          Length = 276

 Score =  174 bits (442), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 51/193 (26%), Positives = 80/193 (41%), Gaps = 4/193 (2%)

Query: 59  VSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDA-IRTFKLLGCELLFCTNA 117
           VST  G A  +++G + G         G         I   A +     LG E +   NA
Sbjct: 26  VSTPWGDAT-ILMGQIGGRDAAVNLRYGEKLTTPSHKINYQANLFALHELGVESIISQNA 84

Query: 118 AGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAK 177
            GS+ P +  G +V   D ++          ++     R     + +    R  L + A 
Sbjct: 85  IGSVNPAIRPGDIVISDDFLDKTKSRAQSLFDESECWVR-VDFTDPFCPRLRTNLIEAAN 143

Query: 178 EE-GFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSA 236
                 +  G FV   GP FET AEIR   + GGD+VG  +VPEVI AR  ++   +++ 
Sbjct: 144 RHSNRVIHRGTFVCTEGPRFETPAEIRAYAMEGGDIVGTPLVPEVIFARELEMCFASIAP 203

Query: 237 ITNMAEGLSDVKL 249
           + N   G++   +
Sbjct: 204 VINFGAGMAPAVV 216


>UniRef50_UPI0000164ED7 purine nucleoside phosphorylase n=1 Tax=Halobacterium sp. NRC-1
           RepID=UPI0000164ED7
          Length = 206

 Score =  173 bits (438), Expect = 7e-42,   Method: Composition-based stats.
 Identities = 53/216 (24%), Positives = 77/216 (35%), Gaps = 17/216 (7%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQ--GVPVVCMKGR 85
           + FI GSG+   A  + +    +     G P + V        +G     G  V  +   
Sbjct: 2   IGFIGGSGIYD-ALPLNDVRETAVSTPYGDPSAPV-------TIGEFGDTGTEVAFLPRH 53

Query: 86  G--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
           G  H      +    + I  FK LG E +  +NA GSLR E+   +LV      +     
Sbjct: 54  GSDHQRSPTNLPYRAN-IYAFKQLGVERILASNAVGSLRDELSPQTLVIPDQIFDRTNHR 112

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL--TEGVFVSYPGPNFETAAE 201
                 D          A+ Y       L   A +         G +V   GP + T AE
Sbjct: 113 DATFFGDG--VVVHQPFADPYCPHMVEHLHDAATDATDADTQQGGTYVCIEGPQYSTRAE 170

Query: 202 IRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAI 237
               +  G D+VGM+ +PE   ARH  L     S +
Sbjct: 171 SEFYKAQGWDLVGMTAIPEAKLARHSSLVKTHTSVV 206


>UniRef50_A2VPA1 Purine nucleoside phosphorylase deoD n=1 Tax=Mycobacterium
           tuberculosis C RepID=A2VPA1_MYCTU
          Length = 241

 Score =  171 bits (435), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 66/186 (35%), Positives = 94/186 (50%), Gaps = 13/186 (6%)

Query: 92  RGMTIMTDAIRTFKLL--GCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLN 149
           R  T  T  IR  + +  G  L         LR ++  G  V + DH+N    +P+VG  
Sbjct: 66  RDTTCATSCIRFGRPVRQGRRLWCSPTPPVGLRADLQVGQPVLISDHLNLTARSPLVGGE 125

Query: 150 DDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIG 209
                  F  L +AY    R L    A++    L EGV+   PGP++ET AEIRM+Q +G
Sbjct: 126 -------FVDLTDAYSPRLREL----ARQSDPQLAEGVYAGLPGPHYETPAEIRMLQTLG 174

Query: 210 GDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLI 269
            D+VGMS V E I+AR    +V+ VS +TN+A G++   LSHA+ LAA   S      L+
Sbjct: 175 ADLVGMSTVHETIAARAAGAEVLGVSLVTNLAAGITGEPLSHAEVLAAGAASATRMGALL 234

Query: 270 CGFLRK 275
              + +
Sbjct: 235 ADVIAR 240


>UniRef50_Q2FR33 Methylthioadenosine phosphorylase n=1 Tax=Methanospirillum hungatei
           JF-1 RepID=Q2FR33_METHJ
          Length = 224

 Score =  170 bits (432), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 50/249 (20%), Positives = 96/249 (38%), Gaps = 27/249 (10%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +  I G+ L                +   F   T +G +        +G     +    +
Sbjct: 2   LGIIGGTSLLDYQG----------SEFTKFEQHTPYGTSELF-----KGEGFFLLLRHQN 46

Query: 88  FYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG 147
                 +   +  I   KL G + +    + GSL+ ++  GS V   D I   P   ++ 
Sbjct: 47  RCAPHIIPYRSH-IAALKLAGADRIIALGSTGSLQEDIPPGSRVIPDDFICLTPVPTIMN 105

Query: 148 LNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQI 207
              D     F       DA+ R LL K++ E    +  G ++   GP  E+ AEI  M+ 
Sbjct: 106 HTIDHVNPEF-------DADLRTLLMKLSPE---AIQRGTYIQTRGPRLESKAEISWMKR 155

Query: 208 IGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFIN 267
              D+VGM++  E+  A    L   A+  + N A G+ D ++++   +     +++  ++
Sbjct: 156 F-ADIVGMTIGSELTVAAELGLPFAAICTVDNYANGVCDAQITYESIIRTVRENQEKALD 214

Query: 268 LICGFLRKI 276
           L+   +  +
Sbjct: 215 LLGRIINSV 223


>UniRef50_Q0CL04 Purine nucleoside phosphorylase n=1 Tax=Aspergillus terreus NIH2624
           RepID=Q0CL04_ASPTN
          Length = 205

 Score =  170 bits (431), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 72/205 (35%), Positives = 94/205 (45%), Gaps = 20/205 (9%)

Query: 4   VQFSHNPLFCIDIIKTYKPDF--TPRVAFILGSGLGALADQIENA--VAISYEKLPGFPV 59
           +         +  +K   P    +PRVA + GSGLG LAD I +       Y  +P FP 
Sbjct: 8   LSSYQQAEQAVQSLKDRLPAELQSPRVAIVCGSGLGGLADSIRDHPRAEYDYGSIPHFPK 67

Query: 60  STVHGHAGELVLGHLQ-GVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAA 118
            TV GHAG+LV G L   +PVV M GR H+YEG  +  +T  IR FKLLG E +     +
Sbjct: 68  LTVPGHAGKLVFGFLGEDIPVVLMVGRAHYYEGHSIHQVTFPIRVFKLLGVETVVFYRGS 127

Query: 119 GSLRPEVGAGSLVALKDHI---NTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKV 175
            +            +  HI         P+ G ND+ FG RF  L++AYD E R  + K 
Sbjct: 128 MT-------KWFTDIAKHIFLSGLAGNHPLRGPNDEEFGPRFPPLSDAYDLELRRHVHKA 180

Query: 176 AKEE-----GFPLTEGVFVSYPGPN 195
            K          L EGV+    GP 
Sbjct: 181 WKTVVDPLSKRRLHEGVYAYVGGPR 205


>UniRef50_B1ZY09 Purine phosphorylase family 2 n=2 Tax=Opitutaceae
           RepID=B1ZY09_OPITP
          Length = 232

 Score =  169 bits (429), Expect = 7e-41,   Method: Composition-based stats.
 Identities = 62/253 (24%), Positives = 106/253 (41%), Gaps = 26/253 (10%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           +VAFI  SG   +   + +A  +          +T +G       G       V +   G
Sbjct: 2   KVAFI--SGTSIVNSDLFSAWEVK-------TTTTPYGQVTYKTKG-----DFVLINRHG 47

Query: 87  HFYE--GRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
           + +      +    + IR    LG + +   N+ GSL+ ++  G+ V+  D++    G P
Sbjct: 48  YAFPLPPHSINYRAN-IRALADLGFKDILSLNSVGSLKRDLPPGTFVSCSDYVGLQQG-P 105

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFETAAEIR 203
           M   + +  G       N        L++K+A E  F +  G V+V + GP FET AEIR
Sbjct: 106 MTFFDQELKGGAPGIANNL----IPLLIEKLAPE--FKIHPGKVYVQFRGPRFETKAEIR 159

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQ 263
           ++Q  G DVVGM+   E        L+  +++ I N A GL   ++  A+     + ++ 
Sbjct: 160 IVQSWG-DVVGMTAAHEADLCSELGLRYNSLALIDNYANGLEGTEIDFAKFKDLVKDNQA 218

Query: 264 NFINLICGFLRKI 276
               L    L  +
Sbjct: 219 KVNRLFTRILEIL 231


>UniRef50_Q5C0P1 SJCHGC05230 protein (Fragment) n=1 Tax=Schistosoma japonicum
           RepID=Q5C0P1_SCHJA
          Length = 186

 Score =  168 bits (425), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 60/150 (40%), Positives = 80/150 (53%), Gaps = 4/150 (2%)

Query: 14  IDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH 73
            D I        P V  I GSGLG LAD I++   I Y+ +P FP +++ GH+G LV G 
Sbjct: 38  ADHI-QKLTCIVPEVGIICGSGLGKLADGIKDKKIIPYKDIPNFPQTSIPGHSGNLVFGT 96

Query: 74  LQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVAL 133
           + G  V+ M+GR H YEG     +   IR  K+LG ++L  +NAAG L   +  G  V L
Sbjct: 97  ISGRNVIVMQGRFHMYEGYNKDEIALPIRVMKILGVKILMVSNAAGGLNRSLKCGDFVIL 156

Query: 134 KDHINTMP---GTPMVGLNDDRFGERFFSL 160
           KDHI          +VG N + FG RF +L
Sbjct: 157 KDHIYFPGLGLNNILVGPNQEEFGPRFPAL 186


>UniRef50_Q9RIJ1 Purine nucleoside phosphorylase homolog (Fragment) n=1
           Tax=Streptococcus pyogenes RepID=Q9RIJ1_STRPY
          Length = 149

 Score =  168 bits (425), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 61/149 (40%), Positives = 86/149 (57%), Gaps = 1/149 (0%)

Query: 127 AGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEG 186
            G+L+A+ DHIN     P++G N D FG RF  +++AY   YR    +V  +    L +G
Sbjct: 2   TGTLMAITDHINMTGNRPLIGENLDEFGPRFPDMSDAYTKVYRDKAHEVHDKMNIKLEDG 61

Query: 187 VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD 246
           V++   GP +ET  EIR  Q +G D VGMS+VPEVI A H  LKV+ +SAITN A G   
Sbjct: 62  VYLGLTGPTYETPGEIRASQGLGEDPVGMSLVPEVIVAAHSGLKVLGISAITNFAAGFQS 121

Query: 247 VKLSHAQTLAAAELSKQNFINLICGFLRK 275
             LSH + +   +  K++F  L+   L +
Sbjct: 122 E-LSHEEVVEVTQHIKEDFTGLVKAILAE 149


>UniRef50_C9KQI5 Phosphorylase, family 2 n=1 Tax=Mitsuokella multacida DSM 20544
           RepID=C9KQI5_9FIRM
          Length = 289

 Score =  166 bits (421), Expect = 7e-40,   Method: Composition-based stats.
 Identities = 51/267 (19%), Positives = 87/267 (32%), Gaps = 15/267 (5%)

Query: 15  DIIKTYKPDFTPRVAFILGSGL--GALADQIENAVAISYEKLPGFPVSTVHGHAGELVLG 72
             +K   P      A + GSG         + +      E    F   T +G +  + L 
Sbjct: 6   QAVKAEIP--RADYAVVGGSGTLSSDFPRNLPDEDVKILEDNLYF--ETPYGKSPSMRLF 61

Query: 73  HLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            +    V+ ++  G                 F+  G + +      G++   +     + 
Sbjct: 62  CVGEKHVLTVRMHGWRSGVTRADASRQVFWVFREAGVKRIISEGGVGTVNKLLDLRDFII 121

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE--EGFPLTEGVFVS 190
             D+++          +    G     + +A   E R  L K  K+   G   T G +  
Sbjct: 122 PDDYLDLSVR-----KDVMLDGRYLLVMRDALCPEMREALIKATKKRFTGRVFTRGTYAV 176

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLS 250
             G +FE+ AE+ MM     D+VG S+ PEV  AR        +    N  EG+     S
Sbjct: 177 TDGRHFESPAEVAMMNG-HADIVGQSIAPEVYLAREIGACYAGLYFTVNYGEGIRKAW-S 234

Query: 251 HAQTLAAAELSKQNFINLICGFLRKIA 277
           H                +I   +R +A
Sbjct: 235 HQDMADIFYDDAPMIGEIILETIRTVA 261


>UniRef50_Q2RHE2 Purine phosphorylase, family 2 n=1 Tax=Moorella thermoacetica ATCC
           39073 RepID=Q2RHE2_MOOTA
          Length = 283

 Score =  165 bits (419), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 50/261 (19%), Positives = 89/261 (34%), Gaps = 14/261 (5%)

Query: 23  DFTPRVAFILGSGLGAL--ADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVV 80
                + FI GSG  +L   D + +       +   F   T  G +  L L      P  
Sbjct: 5   KIQADIGFIGGSGTFSLNFPDALRDPGTEVLAREVVFT--TPWGPSAPLTLFTTGDPPRR 62

Query: 81  CMKGRGH-FYEGRGMTIMT-DAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
            +  + H    G      +      F       +      GS+   +    +V + D+I+
Sbjct: 63  VLAAKMHGRIPGVSWGESSQRLFHAFMQANVRKIIAEGGVGSINHLLDLRDIVVVTDYID 122

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKE--EGFPLTEGVFVSYPGPNF 196
                     +          +           L + A+E   G     GV++   G +F
Sbjct: 123 FSLRR-----DVGLQEGYLSIMRRPICPSLHRTLVETARESPLGRVFDRGVYLVTDGRHF 177

Query: 197 ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLA 256
           E+AAE+ + +  G DVVG ++ PEV  AR        +  + N  EG+      H +   
Sbjct: 178 ESAAEVSLFRQWGADVVGQTLCPEVYLAREMGACYAGIYLVVNYGEGVVK-PWEHRELKE 236

Query: 257 AAELSKQNFINLICGFLRKIA 277
               +  +F  +I   L +++
Sbjct: 237 LFFEAAPDFGRIILKALGRVS 257


>UniRef50_A9B0Q9 Purine phosphorylase family 2 n=1 Tax=Herpetosiphon aurantiacus
           ATCC 23779 RepID=A9B0Q9_HERA2
          Length = 253

 Score =  163 bits (413), Expect = 6e-39,   Method: Composition-based stats.
 Identities = 49/223 (21%), Positives = 83/223 (37%), Gaps = 9/223 (4%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +  + G+G   L       +  +        + T +G AG +         +      G 
Sbjct: 2   ILLLGGTGTYFL------ELEATLGAGNYQTIETPYGTAGSIYQPERFAGKIGLASRHGW 55

Query: 88  FYEGRGMTIM--TDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
                    +     I   K LG + +   N  G++   +    LV L   +N     P+
Sbjct: 56  GRLDVSPPFVNSRANIWAAKELGYQNILSWNGVGAINQLLQVHDLVVLNHVLNGTKTRPI 115

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKE-EGFPLTEGVFVSYPGPNFETAAEIRM 204
               D      +      +D    ++L + A+  +      G +    GP  ETAAEIR 
Sbjct: 116 NFAGDLPNASAWQIAQRVFDPASASVLYQQARRYQARSFDCGTYACSEGPRLETAAEIRA 175

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDV 247
               G DVVGM++VPEV+ A    +K  +++ +TN A G+   
Sbjct: 176 WANFGADVVGMTLVPEVLLAYELGIKFASLAYVTNFATGVEPS 218


>UniRef50_A7BDZ0 Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus
           ATCC 17982 RepID=A7BDZ0_9ACTO
          Length = 265

 Score =  163 bits (413), Expect = 7e-39,   Method: Composition-based stats.
 Identities = 72/274 (26%), Positives = 112/274 (40%), Gaps = 20/274 (7%)

Query: 2   SQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIE--NAVAISYEKLPGFPV 59
            Q       +    I+ +      P     LGSGL    D+     A  +S   +PG   
Sbjct: 8   PQALLDDEAVAGARILTSLAG--RPDALVALGSGLSEALDEAWGAPAATVSLGDIPGVVA 65

Query: 60  STVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAG 119
               GH GEL      G  V+   GR H YEG G+  +    R     G      TNA G
Sbjct: 66  PVADGHGGELRAYEACGGVVLVATGRTHLYEGLGVRPVAALARAAVAAGISRAVLTNANG 125

Query: 120 SLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEE 179
            L+P    G ++A+ DH+N    +P  G         F  ++  +DA+    L+ V +  
Sbjct: 126 CLKP-WNLGDVMAITDHVNLSGASPFDGP-------LFLDVSAVWDAQMTQALRGVCQ-- 175

Query: 180 GFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
                EG +    GP ++T AE R++  +G D VGMS V E I+     ++V  +S +++
Sbjct: 176 ----REGTYAILRGPEYQTMAETRILSGLGVDCVGMSTVMEAITLHALGVRVAGMSVVSD 231

Query: 240 MAEGLSDVKLSHAQTLAAAELSKQNFINLICGFL 273
           +    +D        + AA  ++Q  +  I   L
Sbjct: 232 L--SFADGPTDPTAVVEAASAARQTVVAGIEAAL 263


>UniRef50_Q2LVG5 Phosphorylase family 2 protein n=1 Tax=Syntrophus aciditrophicus SB
           RepID=Q2LVG5_SYNAS
          Length = 240

 Score =  161 bits (409), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 58/253 (22%), Positives = 103/253 (40%), Gaps = 27/253 (10%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +  I G+        I     + +  L    + T +G A  +         VV +   G 
Sbjct: 4   LGIISGT-------VIPQGREL-FGDLQEEFIETEYGQAVVMRSD-----AVVFLPRHGT 50

Query: 87  ---HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGT 143
               +     +    + ++    L    +   N+AGSL  +   G+++   D I      
Sbjct: 51  DPNRYILPHQINHRAN-MKALCELSVREIVAINSAGSLHRKWKPGTIMVPDDFIMLTG-- 107

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFETAAEI 202
            + G++  +       L    D + R  L + A+EEG  +   GV+   PGP  ET AEI
Sbjct: 108 -IPGIHQTQAAHLTPQL----DLKVRHYLLEAAREEGVNVIDRGVYWQMPGPRLETRAEI 162

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
           RM+     D+VGM++  E ++A+   L   A+ +I N   GL +  L+  + +A A  + 
Sbjct: 163 RMISRF-ADLVGMTLASEAVTAQELGLAYGALCSIDNYGNGLVEKLLTVEEIVAHARENA 221

Query: 263 QNFINLICGFLRK 275
           +  I +   +L K
Sbjct: 222 RVMIGIATRYLEK 234


>UniRef50_B3PJG7 Methylthioadenosine phosphorylase n=1 Tax=Cellvibrio japonicus
           Ueda107 RepID=B3PJG7_CELJU
          Length = 308

 Score =  161 bits (408), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 58/253 (22%), Positives = 91/253 (35%), Gaps = 28/253 (11%)

Query: 10  PLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGEL 69
           PL     +    P    R+A I G+ L  +    +            F + T  G + ++
Sbjct: 21  PLAASAAVPADIP--RARIAVIGGTFLNDIFFYRDVVKK-------EFTLETTLGTSPKI 71

Query: 70  VLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGS 129
                 G+P   +   G     +              LG E       AG++ P +    
Sbjct: 72  YYAEWDGIPFYYVHNHGDGQWQQTWV-------ALYDLGVEEAIGGATAGAINPSMKVYD 124

Query: 130 LVALKDHINTMPGTPMVGLND---DRFGERFFSLANAYDAEYRALLQKVAKEE------- 179
            +   D I+     P+        D        L  A D + R +L +  ++        
Sbjct: 125 YIIPHDLIDMNIDRPLGFPKQVYRDPNAIPLPRLTPAMDTDLRQILLEQTRKAIKADKRY 184

Query: 180 -GFPLT-EGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAI 237
             F +  +GV V   G  FET AEI+M    GGD+V MSV  E++ AR   +    V  I
Sbjct: 185 KSFKVHDKGVIVQARGGRFETVAEIKMFGQWGGDLVTMSVGTEIVYARQLGINYATVVVI 244

Query: 238 TNMAEGLSDVKLS 250
           +N AEG+ +   S
Sbjct: 245 SNPAEGVGEWDFS 257


>UniRef50_D1J9Q0 Putative uncharacterized protein n=2 Tax=uncultured archaeon
           RepID=D1J9Q0_9ARCH
          Length = 245

 Score =  161 bits (408), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 59/254 (23%), Positives = 100/254 (39%), Gaps = 27/254 (10%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           ++  I G+ L      +E A            V T +G A  LV   L     V +   G
Sbjct: 14  KLGVIGGTSLFG-TKLLEGAKEKE--------VETKYGRAYLLVTDEL-----VFIPRHG 59

Query: 87  HF--YEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTP 144
                    +    + + +FKLL  E +    + GSL+  +   SLV   D+I       
Sbjct: 60  KATNIPPHRINYRAN-LASFKLLDVEKIIGATSVGSLKRAITPRSLVVPHDYICL--YNI 116

Query: 145 MVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIR 203
               +D+        +    D   R+ + +VA E    + E GV+     P  ET AEIR
Sbjct: 117 PTVYDDE-----IVHVTPGLDDGLRSTIIEVANELDMEIFEQGVYFQTVAPRLETKAEIR 171

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKL-SHAQTLAAAELSK 262
            M+    DVVGM++  E   A    L+   +S + N A G+ + ++  + + +  A  S+
Sbjct: 172 FMRNY-ADVVGMNMASEATLAMELGLRYADISTVDNYAHGIIEEEVLDYKKIVEDASKSR 230

Query: 263 QNFINLICGFLRKI 276
            +   ++   +  I
Sbjct: 231 VDLEKVLIKLIEVI 244


>UniRef50_C0W926 Purine-nucleoside phosphorylase n=1 Tax=Actinomyces urogenitalis
           DSM 15434 RepID=C0W926_9ACTO
          Length = 286

 Score =  160 bits (405), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 60/277 (21%), Positives = 99/277 (35%), Gaps = 25/277 (9%)

Query: 10  PLFCIDIIKTYKPDFTPRVAFILGSGLGA-LADQIENAVAISYEKLPGFPVSTVHGHAGE 68
            L     I          +  +LGSG    L    E    +    LPG       GH   
Sbjct: 24  ALDAAHQIARRTGADHHDLLVVLGSGADGALEGWGEPEATLPLSDLPGVLAPAAPGHRDL 83

Query: 69  LVLGHL--------QGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           L             +G+ V+   GR H YEG G   +    R     G       NA G 
Sbjct: 84  LASYRRTLPGDDGDRGLRVLVAYGRTHLYEGHGSAPVVALARAAAAAGVRAAVLVNANGC 143

Query: 121 LRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEG 180
           LR +   G ++ + DH+N    +P         G  F  +   +D     +L+K      
Sbjct: 144 LR-DWRLGEVMTITDHLNLTGSSPF-------DGTVFVDVREVWDRRLAQVLRK------ 189

Query: 181 FPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNM 240
               EG + +  GP ++T AE R +   G D VGMS V E I+     ++V  +S ++++
Sbjct: 190 RTEREGTYAALRGPEYQTMAETRWLAGGGADAVGMSTVLEAIALHQLGVRVAGMSVVSDL 249

Query: 241 AEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKIA 277
               +       + +     +     + +   + ++A
Sbjct: 250 --SFAAEATDPEEVVRLVRGAHATLADGVDAVVAELA 284


>UniRef50_A4IXW9 Phosphorylase family 2/alpha-beta hydrolase fold protein n=18
           Tax=Francisella RepID=A4IXW9_FRATW
          Length = 611

 Score =  160 bits (405), Expect = 5e-38,   Method: Composition-based stats.
 Identities = 49/254 (19%), Positives = 87/254 (34%), Gaps = 18/254 (7%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHG-HAGELVLGHLQGVPVVCMKGRG 86
            A +  SG  +  D         +E +   P  T  G  +  L    ++   V+ +   G
Sbjct: 2   WAIVGSSGFESFDD---------FEIIEELPRETPFGLCSNGLFKIKVEDKEVLFLNRTG 52

Query: 87  HF--YEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG-T 143
                    +    + I   K  G   +   ++  SLR E+  G +V     I+      
Sbjct: 53  LGQNILPHQINYKAN-IYALKKYGATSIIALSSVRSLREELKPGDMVIPYQFIDRTKSLR 111

Query: 144 PMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEI 202
                        + SL+          ++   KE  F +  +  +V   GP F T  + 
Sbjct: 112 EFTFCEQGLLN--YVSLSKPITESIAEEIRAKKKEFDFEIHFKQSYVCIEGPQFPTIIDA 169

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSK 262
           +  Q +GG V+GM+  PE   AR   L  ++ + I +      DV+ +    L   E S 
Sbjct: 170 KCFQSMGGGVIGMTAFPEFALAREAGLNYISCNFIVDYVPWSYDVR-NLYNVLEIRETSN 228

Query: 263 QNFINLICGFLRKI 276
                L+   +  +
Sbjct: 229 LKAEKLVKWLVNNL 242


>UniRef50_C7DHY9 S-methyl-5-thioadenosine phosphorylase n=1 Tax=Candidatus
           Micrarchaeum acidiphilum ARMAN-2 RepID=C7DHY9_9EURY
          Length = 278

 Score =  157 bits (397), Expect = 4e-37,   Method: Composition-based stats.
 Identities = 51/257 (19%), Positives = 91/257 (35%), Gaps = 20/257 (7%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           V  I G  +  LAD  E      ++   G P S        L+LG + GV +  M+    
Sbjct: 18  VGIIGGPEILELADYREKKE---FDTEYGKPSSP-------LMLGSIAGVDIAAMRRDAI 67

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
                 + +  + + I+ F+ LG + +   ++  ++R +  AG  V     IN   G   
Sbjct: 68  DGGLSPQNIPYLAN-IKAFESLGVKRIIAISSVATMRSDFVAGDFVFPSHFINMSNGRRD 126

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNFETAAEIR 203
              +              Y ++      K A   G+     E   +   G    T AE R
Sbjct: 127 TFFDSG--NVLRIGDPKPYCSDIAYWGAKAADNLGYIKYHKESTVIITNGTRRPTLAESR 184

Query: 204 MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA---EL 260
           +    G DV+     PE++ A+   +   AVS + +    + ++  S    +      + 
Sbjct: 185 LFAGWGCDVIDYYQYPEIVLAKEKGICYGAVSMVLDYDSIVEELGKSFRAYVDMEGQYKR 244

Query: 261 SKQNFINLICGFLRKIA 277
           +      L+   L  IA
Sbjct: 245 TISGLKALLSEMLPNIA 261


>UniRef50_A2SSB6 Methylthioadenosine phosphorylase n=2 Tax=Methanomicrobiales
           RepID=A2SSB6_METLZ
          Length = 223

 Score =  157 bits (397), Expect = 4e-37,   Method: Composition-based stats.
 Identities = 51/251 (20%), Positives = 92/251 (36%), Gaps = 30/251 (11%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +  I G+ L  L  ++     I      G    +V  H G           +V +    +
Sbjct: 2   LGIIGGTAL--LQARLPPLEKIRVSTPFG----SVQAHVG----------RIVFISRHQN 45

Query: 88  FYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG 147
                 +      +   K+LG + L    + GS+  ++  GS+V   D  +     P + 
Sbjct: 46  DTPPHRVNHRAH-LAAMKILGVDKLIVIGSTGSMHDDLPPGSIVIPDDSFSP-WDIPSLH 103

Query: 148 LNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQI 207
            ND       + +  + +   R  L ++  E       G +    GP FET AEI     
Sbjct: 104 DND------IYHIPPSINPGLREELVRIVPEA----KPGTYFQTLGPRFETRAEIACFAG 153

Query: 208 IGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDV-KLSHAQTLAAAELSKQNFI 266
              DVVGM+   E+  A    +   A+  + N A G+       + + +A A  + +   
Sbjct: 154 D-TDVVGMTAASELTLANELGIPCAALCTVDNYANGIGGASAPEYDEIVAIARRNGERIT 212

Query: 267 NLICGFLRKIA 277
           ++I   + K+A
Sbjct: 213 DIITKIVEKLA 223


>UniRef50_UPI0001C31DF7 S-methyl-5''''-thioadenosine phosphorylase n=1 Tax=Conexibacter
           woesei DSM 14684 RepID=UPI0001C31DF7
          Length = 264

 Score =  155 bits (393), Expect = 1e-36,   Method: Composition-based stats.
 Identities = 62/259 (23%), Positives = 95/259 (36%), Gaps = 20/259 (7%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR- 85
           RV  I GSG   L    +          PG  V T  G A EL  G   GV VV +    
Sbjct: 2   RVGIITGSGSYVLPHVADGV--------PGRVV-TRFGTA-ELTRGTFAGVDVVYVSRHL 51

Query: 86  -GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHI---NTMP 141
            GH      +    + I      G + +      GSL   +  G+LV   D     N +P
Sbjct: 52  PGHRLLSSQVRHRAN-IVALAEAGVDAIVAVTICGSLDASLPPGALVVFDDLYFPSNRLP 110

Query: 142 GTPMVGLNDDRF--GERFFSLANAYDAEYRALLQKVAKEEGFPLTEG-VFVSYPGPNFET 198
              +  L+DD    G   +     +    R  L   A+  G+   +G  +    GP F T
Sbjct: 111 DGSICTLHDDPGASGRGHWIFDLPFSQPLREALLTGARSAGYAARDGGCYAHTDGPRFNT 170

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGL-SDVKLSHAQTLAA 257
            AE+R +  IG   V  +  PE++ +    +    +  IT+ A G+  D      +    
Sbjct: 171 RAELRALMQIGVKAVSQTAGPEIVLSGEAGVPYALLGFITDYANGINPDDPTPVDELARL 230

Query: 258 AELSKQNFINLICGFLRKI 276
            + S     +++   L +I
Sbjct: 231 LDASGDIVADVLAATLPRI 249


>UniRef50_B5JG81 Phosphorylases family 2 n=1 Tax=Verrucomicrobiae bacterium DG1235
           RepID=B5JG81_9BACT
          Length = 230

 Score =  150 bits (379), Expect = 5e-35,   Method: Composition-based stats.
 Identities = 54/253 (21%), Positives = 95/253 (37%), Gaps = 29/253 (11%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG- 86
           +  I G+           A +  +       V+T  G       G L     V +   G 
Sbjct: 1   MGIISGT---------SIARSELFADWEAREVATQFGEVQVREKGDL-----VVLNRHGF 46

Query: 87  -HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
                   +    + I     LG   +   ++ GS  P++  GSLV+  D+++  P T  
Sbjct: 47  ERPLPPHAVNYRAN-IEALCQLGIRSVVTLSSVGSADPDLPPGSLVSCSDYMSFAPKT-- 103

Query: 146 VGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFP-LTEGVFVSYPGPNFETAAEIRM 204
               DDR       L+N +       L  +A       + + V++   GP FET AE+R 
Sbjct: 104 --FIDDRTSAFAPVLSNPH-------LAGIASRSSVEIVRDKVYMQTRGPRFETKAEVRA 154

Query: 205 MQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQN 264
           ++ +G DVVGM+   E        ++V A   + N A G++  +LS     A    ++  
Sbjct: 155 IRTLGADVVGMTFGNEADLLLERGIEVTAFCMVDNFAHGVNSAELSMEAFEALVASNQVR 214

Query: 265 FINLICGFLRKIA 277
               +   +  ++
Sbjct: 215 INQFLSDLVDYLS 227


>UniRef50_Q67R93 Methylthioadenosine phosphorylase n=1 Tax=Symbiobacterium
           thermophilum RepID=Q67R93_SYMTH
          Length = 265

 Score =  149 bits (376), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 51/237 (21%), Positives = 84/237 (35%), Gaps = 31/237 (13%)

Query: 30  FILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH-- 87
            I G+    L  Q +              V T  G AG   +  + G PV  +   G   
Sbjct: 6   IIGGTAAYHL--QFDPGWT-------ERTVETPFGPAGPFRIFAVAGRPVAFLSRHGGEG 56

Query: 88  --FYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
                   +    + +   + LG   +   N+AGS+   +  GSL  + D I+     P 
Sbjct: 57  RLGVTPPFINYRAN-VWAARALGARRVLSWNSAGSMVRALPPGSLAVVSDLIDWTRRRPD 115

Query: 146 VG----------------LNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVF 188
                                        + A  +D + RA L + A   G       V+
Sbjct: 116 SFGAAARDPAVRDTVVRHPAPPAGHATGPAYAGLFDPDLRARLVQAAAACGHRAAPRAVY 175

Query: 189 VSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS 245
            +  G   ET AEI ++   G ++VGM++ PEV  AR   +   ++  ++N A G+ 
Sbjct: 176 AATEGARLETRAEIALLAQAGAELVGMTLAPEVFLARELGMAYGSICWVSNYATGVP 232


>UniRef50_A8RJ25 Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC
           BAA-613 RepID=A8RJ25_9CLOT
          Length = 289

 Score =  148 bits (375), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 43/258 (16%), Positives = 84/258 (32%), Gaps = 20/258 (7%)

Query: 31  ILGSGLGA--LADQIE------NAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCM 82
           I GSG       + +           + +E   G             +    +   V+ +
Sbjct: 14  IGGSGTWGCEFPEDLNMEGITLLKRDMEFETPFGVTACMKLYEMDASITADHKTRQVLYV 73

Query: 83  KGRGHFYEGRGMTIMT---DAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINT 139
               H ++G      T         +  G + +    + G + P +  G ++  +D I+ 
Sbjct: 74  P--FHGWKGLSPYNDTPSERIFWALREAGVKYILADGSGGGINPLLEPGDIICPQDFIDY 131

Query: 140 MPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFET 198
                 +G    +F      +      +   +L + A      +   G++     P FE+
Sbjct: 132 TKRVSYLG----KFTPYSMRMREIICPDLHRILLEKASGVFRRVFRTGIYGVAEAPRFES 187

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
           AAEI+ M     DV G +++PE   AR       A+  I+N AEG++             
Sbjct: 188 AAEIQKMYADHCDVCGQTMMPEAALARAIGACYAALYVISNSAEGINPNW--ERSIFDIY 245

Query: 259 ELSKQNFINLICGFLRKI 276
                    ++   +  I
Sbjct: 246 SECAPVVGKVMLEAMAAI 263


>UniRef50_UPI0000D5796F PREDICTED: similar to purine nucleoside phosphorylase, partial n=1
           Tax=Tribolium castaneum RepID=UPI0000D5796F
          Length = 153

 Score =  146 bits (369), Expect = 7e-34,   Method: Composition-based stats.
 Identities = 49/129 (37%), Positives = 73/129 (56%), Gaps = 4/129 (3%)

Query: 153 FGERFFSLANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNFETAAEIRMMQIIGG 210
           FG RF  +  AY+ E     +KVA+E G    + EG +    GPNFET AE+RM++++G 
Sbjct: 20  FGPRFPPMNKAYNRELIDQGKKVARELGMGGMVHEGTYTCLGGPNFETVAELRMLKMLGA 79

Query: 211 DVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD--VKLSHAQTLAAAELSKQNFINL 268
           D VGMS V EVI+ARHCD+ V+A S ITN+     +   K +H + +   ++ +      
Sbjct: 80  DAVGMSTVHEVITARHCDMTVLAFSLITNICITDYECHDKPNHEEVMDVGKMRQDTLKLF 139

Query: 269 ICGFLRKIA 277
           +   +  IA
Sbjct: 140 VKKLVEYIA 148


>UniRef50_Q9RKG9 Putative phosphorylase n=1 Tax=Streptomyces coelicolor
           RepID=Q9RKG9_STRCO
          Length = 262

 Score =  143 bits (361), Expect = 6e-33,   Method: Composition-based stats.
 Identities = 62/259 (23%), Positives = 94/259 (36%), Gaps = 19/259 (7%)

Query: 27  RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRG 86
           R+  I GSG       +E A   +     G    T          G L G  +V +   G
Sbjct: 2   RIGVITGSGSYDWPH-LEGAAERTVVTEHGAVTVTE---------GRLGGAEIVQLSRHG 51

Query: 87  --HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHI---NTMP 141
             H      +    +      +    ++  T   GSL P+V  GSLV   D     N +P
Sbjct: 52  TGHHRLSSQVDHKANLAALLAVEAEAVVSFT-VCGSLEPDVRPGSLVVFDDLYFPANRLP 110

Query: 142 -GTPMVGLNDDRF-GERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYPGPNFET 198
            GTP    +     G   +     +    R  L   A + G P+ T+GV+    GP F T
Sbjct: 111 DGTPCTWYDTPGGAGRGHWIFDRPFSEPLRQALITAADQTGVPVATQGVYGHVDGPRFNT 170

Query: 199 AAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
             E+  +   G   +  +  PEV+ A   +L +V V  +T+ A G++         L   
Sbjct: 171 RPEVAALAAAGVSAISQTAGPEVVLAGEAELPMVLVGFVTDYANGVAPEPEPVQALLDRM 230

Query: 259 ELSKQNFINLICGFLRKIA 277
             SK  F  L    L  ++
Sbjct: 231 AASKDVFAKLAEHALPSLS 249


>UniRef50_D0NYY4 Putative uncharacterized protein n=1 Tax=Phytophthora infestans
           T30-4 RepID=D0NYY4_PHYIN
          Length = 265

 Score =  142 bits (359), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 58/266 (21%), Positives = 93/266 (34%), Gaps = 24/266 (9%)

Query: 22  PDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGV---- 77
              T  +  I GS L          V    E   G  V     H G    G         
Sbjct: 2   ISRTHVLGVIGGSSLFHAKSFSSGLVEQVVETEFGAVVC----HVGTWPSGSQDETSPAL 57

Query: 78  PVVCMKGR-----GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVA 132
            +V ++       G + + R +     A+   K L CE +    + GS+ P+VG G  V 
Sbjct: 58  QLVFVQRHHADPDGKYRQPRKINFRAIAL-ALKSLRCEAVVGIYSVGSMTPKVGVGRFVV 116

Query: 133 LKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGF-PLTEGVFVSY 191
            +D       +P   ++  +  +          A+ +  L +     GF P   GV+V  
Sbjct: 117 PEDFF-----SPFDIMHVSKDYDAHV--VPELHAKLKTALVQALTGGGFDPHDGGVYVQT 169

Query: 192 PGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSH 251
            GP FET +E+R     G  ++GM+   E        +     S + NMA G+ D  L+ 
Sbjct: 170 AGPRFETKSEVRFFAQFG-QLIGMTGANEAELLNELRVPFAMFSIVDNMANGMGD-PLTL 227

Query: 252 AQTLAAAELSKQNFINLICGFLRKIA 277
               A  + +           L ++A
Sbjct: 228 EAFKATQKANADLMERAFVHTLNELA 253


>UniRef50_A7I6C4 Purine phosphorylase, family 2 n=2 Tax=Genera incertae sedis
           RepID=A7I6C4_METB6
          Length = 223

 Score =  140 bits (352), Expect = 8e-32,   Method: Composition-based stats.
 Identities = 54/249 (21%), Positives = 96/249 (38%), Gaps = 28/249 (11%)

Query: 28  VAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGH 87
           +  I G+ L              +  LP     TV    GE  L  L G  +V +    +
Sbjct: 2   LGIIGGTSL-------------LFSTLPALKKETVATPFGEAEL--LCG-DIVMLMRHQY 45

Query: 88  FYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVG 147
                 +    + +    + G + +    ++GSL+ E+  G+ +   D+++     P + 
Sbjct: 46  GRPPHRINYRAN-LAAMAISGVDHIVAFGSSGSLKKEIPPGTTLIPTDYVSMA-DIPSIH 103

Query: 148 LNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQI 207
            +         S         RAL +K+A         GV+V   GP  ET  E+  +  
Sbjct: 104 DHAIEHVRPELS---------RALAEKLAAVVPEARLGGVYVQTRGPRIETVTEVAALAQ 154

Query: 208 IGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFIN 267
           I  DVVGM+V  E   A   D++  A+  I N A GL    L+    L+ ++   +    
Sbjct: 155 I-ADVVGMTVASEATLACELDMEFAALCTIDNYANGLGAEVLTFEHILSISKAHSRRTEE 213

Query: 268 LICGFLRKI 276
           ++   +R++
Sbjct: 214 VLGAIIREM 222


>UniRef50_Q4P1A5 Putative uncharacterized protein n=1 Tax=Ustilago maydis
           RepID=Q4P1A5_USTMA
          Length = 180

 Score =  136 bits (343), Expect = 7e-31,   Method: Composition-based stats.
 Identities = 59/233 (25%), Positives = 85/233 (36%), Gaps = 62/233 (26%)

Query: 1   MSQVQFSHNPLF---CIDIIKTYKPDF--TPRVAFILGSGLGALADQIENAVAISYEKLP 55
           MS V     P+     ++ I+   P    +P+   I GSGL  LA  +E+AV + Y  +P
Sbjct: 1   MSNVDLDSLPVQFKQAVEAIRAAVPAELASPKWGIICGSGLSGLASTLESAVHVPYTSIP 60

Query: 56  GFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCT 115
           GF  STV GH   L  G                Y     +     +              
Sbjct: 61  GFAESTVQGHTSSLAFG----------------YLSTTPSKRVAVVACL----------- 93

Query: 116 NAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKV 175
                                     G       +      F  L+NAYD E R  L + 
Sbjct: 94  --------------------------GRFHTY--EGHSAATFPPLSNAYDLELRLALYRA 125

Query: 176 AKEEGF--PLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARH 226
           A++      L  G +    GP++E+ A+   ++ +G D VGMS VPEVI+A H
Sbjct: 126 AEKLSLLDSLASGTYAYVLGPSYESRADANFLKSVGADAVGMSTVPEVIAAAH 178


>UniRef50_UPI0000E4A236 PREDICTED: similar to GTP-binding protein, partial n=3
           Tax=Strongylocentrotus purpuratus RepID=UPI0000E4A236
          Length = 690

 Score =  136 bits (342), Expect = 9e-31,   Method: Composition-based stats.
 Identities = 42/121 (34%), Positives = 69/121 (57%), Gaps = 4/121 (3%)

Query: 160 LANAYDAEYRALLQKVAKEEGFP--LTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSV 217
           +   YD + R    KVA+E+       +GV++   GP++ET AE R ++ +GGDVVGMS 
Sbjct: 1   MNKVYDEKLRNSALKVAEEQRIAPFTRQGVYLMVGGPSYETPAEARYLRALGGDVVGMST 60

Query: 218 VPEVISARHCDLKVVAVSAITNMAEGLSDV--KLSHAQTLAAAELSKQNFINLICGFLRK 275
           VPEV++ARHC ++ + +S IT++          ++H   L  A+      I+L+ G + K
Sbjct: 61  VPEVLAARHCGMRALGLSLITDIVTMDYGAAGAINHDDFLETAKWRAATMIDLVVGVVEK 120

Query: 276 I 276
           +
Sbjct: 121 M 121


>UniRef50_UPI00016A8371 5''''-methylthioadenosine phosphorylase n=2 Tax=pseudomallei group
           RepID=UPI00016A8371
          Length = 271

 Score =  131 bits (330), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 57/267 (21%), Positives = 103/267 (38%), Gaps = 25/267 (9%)

Query: 27  RVAFILGSGLG-ALADQIENAVAIS-YEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
           R+A I G+GL   L   + N   I       G    TV         G + G+  + +  
Sbjct: 6   RIAIIAGTGLARGLDAFLGNRETIENVRVTFGRRSGTVL----HYTTGRIGGIEAIVLPR 61

Query: 85  RG---HFYEGRGMTIMT-----DAIRTFKLLGCELLFCTNAAGSLRPEVGAGS---LVAL 133
            G      +     ++        I     LG + ++  N+ G++  ++   +    +A 
Sbjct: 62  HGPTLAIPDRSPAELVAELGHEAHIWHLHELGVQAVYAFNSVGAIDLDLPLAADNVFLAP 121

Query: 134 KDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPL-TEGVFVSYP 192
            D+   +        N  +      S+   +DA  RA     A + G  L T+G+++   
Sbjct: 122 DDYARGLSSVSHSFGNLAK--HVHPSMREPFDARLRANFALAAGKVGAKLLTQGLYIQSG 179

Query: 193 GPNFETAAEIRMMQII----GGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLS-DV 247
           G  FE+AAE+   + +       V+GM+   E++  R  ++    + A  N AEGL  D 
Sbjct: 180 GDAFESAAEVETYRRVYQGRRNRVLGMTAGAELVLCRQMEIPYALICANCNWAEGLDPDN 239

Query: 248 KLSHAQTLAAAELSKQNFINLICGFLR 274
            ++HA  LA  + +      +    LR
Sbjct: 240 AVTHAFVLAGMQPAAATLAKIAEAVLR 266


>UniRef50_B9K7V5 Purine nucleoside phosphorylase n=1 Tax=Thermotoga neapolitana DSM
           4359 RepID=B9K7V5_THENN
          Length = 148

 Score =  130 bits (327), Expect = 6e-29,   Method: Composition-based stats.
 Identities = 39/109 (35%), Positives = 57/109 (52%), Gaps = 1/109 (0%)

Query: 12  FCIDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVL 71
              + IK      +P +  +LGSG  +  + ++N   I Y+ +P FP  TV GH+G+LV 
Sbjct: 11  EASEYIKER-TSVSPEILIVLGSGFSSFVEAMDNCTTIDYKDIPHFPQPTVEGHSGKLVF 69

Query: 72  GHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGS 120
           G ++  PV+ M GR H YEG     +   I   K LG + +  TNAAG 
Sbjct: 70  GIVKDRPVMVMAGRFHLYEGHAPQRVAFPIYVAKFLGVKGVIVTNAAGG 118


>UniRef50_UPI0001926077 PREDICTED: similar to nucleoside phosphorylase, partial n=1
           Tax=Hydra magnipapillata RepID=UPI0001926077
          Length = 117

 Score =  129 bits (325), Expect = 9e-29,   Method: Composition-based stats.
 Identities = 47/101 (46%), Positives = 61/101 (60%), Gaps = 1/101 (0%)

Query: 14  IDIIKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGH 73
            D + + K    P +  I GSGLG L + IEN    SYE +PGFPVSTV GHAG+LV G 
Sbjct: 17  SDFLLS-KTQLRPTIGVICGSGLGGLVNNIENKEEFSYEDIPGFPVSTVKGHAGKLVFGT 75

Query: 74  LQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFC 114
           ++   +VC++GR HFYEG G+   T  +R   LLG + L  
Sbjct: 76  IKEKILVCLQGRFHFYEGHGINKCTLPVRVMALLGIKTLMS 116


>UniRef50_C1HCE7 Purine nucleoside phosphorylase n=1 Tax=Paracoccidioides
           brasiliensis Pb01 RepID=C1HCE7_PARBA
          Length = 243

 Score =  129 bits (324), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 61/244 (25%), Positives = 92/244 (37%), Gaps = 36/244 (14%)

Query: 1   MSQVQFSHNPLFCIDIIKTYKPDF--TPRVAFILGSGLGALADQIE--NAVAISYEKLPG 56
           M +             ++   P     PR A I GSGLG LA+ +         Y  +P 
Sbjct: 1   MGEKSIFQQAQETCSYLRERLPVELQKPRFAIICGSGLGGLAESVNKSPKAEFDYASIPH 60

Query: 57  FPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRG-----MTIMTDAIRTFKLL-GC- 109
           FPVST +    +  +  L+           +  +        +          KL+ G  
Sbjct: 61  FPVSTGNLCVVKERITQLESTWPGSFNNEVYLPDNVSNDDANVNACAVPGHVGKLVFGIL 120

Query: 110 -ELLFCTNAAGSLRPEVGAGSLVALKDHI---NTMPGTPMVGLNDDRFGERFFSLANAYD 165
            E +  T+AAG L PE   G +V L DHI         P+ G ND+ FG RF  L++AYD
Sbjct: 121 GENIAVTSAAGGLNPEYEVGDIVILNDHIFLAGLAGIHPLRGANDNEFGVRFPPLSDAYD 180

Query: 166 AEYRALLQKVAKEEGFPLTEGVF---VSYPGPNFE-------TAAEI-----RMMQIIGG 210
              R       +    P  + V+   +   GP  E       ++A+I     + ++    
Sbjct: 181 LGLRK------ECPSRPGEKRVYEEFMHCWGPRRELNAGYYASSAQISLECQQFLKSSWL 234

Query: 211 DVVG 214
           D VG
Sbjct: 235 DTVG 238


>UniRef50_Q2S0L6 5'-methylthioadenosine phosphorylase II n=1 Tax=Salinibacter ruber
           DSM 13855 RepID=Q2S0L6_SALRD
          Length = 263

 Score =  120 bits (302), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 60/258 (23%), Positives = 100/258 (38%), Gaps = 21/258 (8%)

Query: 26  PRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           P VA ILGS   A AD   + + +  E     PV T  G      +  L   P   +   
Sbjct: 2   PAVAAILGS---AFADAFPDELDLEPE-----PVETEWGTQTLHRVRGL-DRPAYVLFRH 52

Query: 86  G--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHI---NTM 140
           G  H      +     A    + +GC  L  T++ G L P+V     + + D +   N +
Sbjct: 53  GLPHRLLPNQINYRAQA-AALRAVGCGALLVTSSVGVLDPDVPLYRPLLVDDLLMPDNRL 111

Query: 141 P-GTPMVGLNDDRFGERFFSLAN-AYDAEYRALLQKVAKEEGFPLTEGV-FVSYPGPNFE 197
           P G+      +         L +  +     A ++ +A+    P+ + V F    GP  +
Sbjct: 112 PDGSACTMFTEPSEAHGHLVLNDGLFATGLSAQVRTLAEGADAPIADTVAFAYVQGPRSK 171

Query: 198 TAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTL-A 256
           TAAE RM   +G  V  M++ PEV+ A   ++    +  +      + D      + L A
Sbjct: 172 TAAENRMWPRMGAQVNSMTLGPEVVLANELEIPCAGL--VVGHKYSIPDRDPPEQEALSA 229

Query: 257 AAELSKQNFINLICGFLR 274
             + S+     ++  FLR
Sbjct: 230 TLDRSRDEQERVVRAFLR 247


>UniRef50_C5KDS7 Methylthioadenosine/purine nucleoside phosphorylase, putative n=2
           Tax=Perkinsus marinus ATCC 50983 RepID=C5KDS7_9ALVE
          Length = 204

 Score =  117 bits (293), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 38/164 (23%), Positives = 61/164 (37%), Gaps = 22/164 (13%)

Query: 104 FKLLGCELLFCTNAAGSLRPE-VGAGSLVALKDHINTM--------PGTPMVGLNDDRFG 154
              L C+ +    + GS+RP+    G +    D I+           G P VG      G
Sbjct: 5   AHELLCDKIIALASVGSIRPDLFKIGDIAVPTDFIDFAPQRGTMTFWGNPDVGPFSGEKG 64

Query: 155 ERFFSLANAYDAEYRALLQKVA------------KEEGFPLTEGVFVSYPGPNFETAAEI 202
              ++  +  D  +R  +                 E     T+ V+    GP FE+ AE+
Sbjct: 65  RIHYTPCDHDDHVWRKKIAGTLFPFQEGPHIVSLSEANETETDVVYTQTNGPRFESRAEV 124

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSD 246
           RM+Q  G  +VGM+   E   A    +    V+ + N+  GL  
Sbjct: 125 RMLQRYG-HLVGMTCASEWTLAGELGVPYAIVAMVDNLGNGLDS 167


>UniRef50_C8SNV7 Purine or other phosphorylase family 1 n=2 Tax=Mesorhizobium
           RepID=C8SNV7_9RHIZ
          Length = 312

 Score =  112 bits (281), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 45/257 (17%), Positives = 81/257 (31%), Gaps = 32/257 (12%)

Query: 3   QVQFSHNPLFCIDIIKTYKPDFTPRVAFILGS---GLGALADQIENAVAISYEKLPGFPV 59
            +  +H+         T  P     +A I GS   GL A  + ++     +  +   F  
Sbjct: 6   NMPTNHHAAVAPACHSTDIPQVG--LAIITGSANWGL-AFPEDVKFESVRTLRRDMSF-- 60

Query: 60  STVHGHAGEL------VLGHLQGV--PVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCEL 111
            T  G +             ++G     +CM   G+  +    +    A       G   
Sbjct: 61  ETPFGRSDNWKLLEFDASITVEGKMKRALCMYSHGNPRDHIDHSCHRRAFWVLMEAGVRQ 120

Query: 112 LFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLA--NAYDAEYR 169
           +   +  G++   +  G +V   D I                G + F  +          
Sbjct: 121 VLSCSTIGAVNKAIKPGDMVVNADIIELTQT-----PFSLLPGRQSFDCSGKQIVCPRCA 175

Query: 170 ALLQKVAKEE--------GFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEV 221
           A+L + A+          G    + V     GP   T AE    + +G DV+  S+ PE 
Sbjct: 176 AVLVETARRHWPAECRVHGIE-QQLVAGHCYGPRLTTPAEALAFRNLGADVLNHSIAPEA 234

Query: 222 ISARHCDLKVVAVSAIT 238
             +R      V ++ +T
Sbjct: 235 TLSREIGACFVPLAFVT 251


>UniRef50_Q67R94 Methylthioadenosine phosphorylase n=1 Tax=Symbiobacterium
           thermophilum RepID=Q67R94_SYMTH
          Length = 251

 Score =  112 bits (280), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 36/147 (24%), Positives = 52/147 (35%), Gaps = 10/147 (6%)

Query: 118 AGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAK 177
              + P +  G LV   D I+     P        +G  F  L   +  E  A L    +
Sbjct: 82  VEPVSPLLEPGDLVVPVDVIDLTRLLPPTFFVGKGYG--FIRLDPPFCPELSAALYAAGR 139

Query: 178 EEGFPLTEG-VFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSA 236
           E+      G  +V   G    T AE RM +  G DVVG  +VPE   AR  +L   A++ 
Sbjct: 140 EKTPRAFRGATYVGLDGSREATPAERRMYRAWGADVVGSGLVPEAFLARELELCYAALTV 199

Query: 237 ITNMAEGLSDVKLSHAQTLAAAELSKQ 263
           +        + +      L  A     
Sbjct: 200 V-------REAQADVLAVLERAAQLAP 219


>UniRef50_P23139 Uncharacterized 25.8 kDa protein in petC 3'region n=1
           Tax=Rhodospirillum rubrum RepID=YPE2_RHORU
          Length = 238

 Score =  100 bits (249), Expect = 5e-20,   Method: Composition-based stats.
 Identities = 25/139 (17%), Positives = 46/139 (33%), Gaps = 11/139 (7%)

Query: 25  TPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKG 84
            P +  I GSG+  + D +E A   + E   G         + +++ G L G+ +  +  
Sbjct: 7   QPVLGVIGGSGVYDI-DGLEGARWQTVESPFGDV-------SDQILRGTLDGLEMAFLPR 58

Query: 85  RG--HFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
            G  H      +    + I   K  G   +   +A GSL  ++  G+ V     I+    
Sbjct: 59  HGRGHVLAPSDVNYRAN-IDALKRAGVTEILSVSAVGSLAEDLPPGTFVIADQFIDRTFA 117

Query: 143 TPMVGLNDDRFGERFFSLA 161
                             +
Sbjct: 118 REKSFFRQGSGRPCQHGPS 136


>UniRef50_C0W509 Possible purine-nucleoside phosphorylase n=1 Tax=Actinomyces
           urogenitalis DSM 15434 RepID=C0W509_9ACTO
          Length = 283

 Score =  100 bits (249), Expect = 6e-20,   Method: Composition-based stats.
 Identities = 48/228 (21%), Positives = 73/228 (32%), Gaps = 16/228 (7%)

Query: 13  CIDIIKTYKPDFTPRVAFILGSGLGALADQIEN--AVAISYEKLPGFPVSTVHGHAGELV 70
               I          +  +    L A  D      A  +    LPG     V G    L 
Sbjct: 22  TAASILLATGRPRHDLLVVAEPALLAELDAAWGRLAARVRLSFLPGVSAPQVPGQEDLLT 81

Query: 71  LGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
                G+ V+  +GR   YEG+    +T   R     G       + A SL      G  
Sbjct: 82  SHDRGGLGVLVARGRTCLYEGKPARRVTGLARLAAGAGVRAALMVSRASSLGQA-SLGDF 140

Query: 131 VALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVS 190
           +A+ DH+N               G   F      DA +   L             GV   
Sbjct: 141 LAVADHLNLT-------------GSPLFPATQCVDASWDEDLTNAVSRIDGVRGAGVAAL 187

Query: 191 YPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
            PGP   + +E+ +M  +G D V M  V E ++     ++V  ++ + 
Sbjct: 188 VPGPVRPSRSEVTLMSGLGADAVVMDGVAEAMALAARGVRVAGLAYVD 235


>UniRef50_C0QJ87 Putative purine nucleoside phosphorylase n=1 Tax=Desulfobacterium
           autotrophicum HRM2 RepID=C0QJ87_DESAH
          Length = 258

 Score = 95.7 bits (237), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 40/217 (18%), Positives = 65/217 (29%), Gaps = 21/217 (9%)

Query: 38  ALADQIENAVAISYEKLPGFP-------VSTVHGHAGELVLGHLQGVPVVCMKG------ 84
             +D  + A+   Y   PGF        VST                  + M        
Sbjct: 5   TWSDLNDRAIIQPYGARPGFESGAVAVMVSTAPDFNYLKANARGNTCSPLFMGSVFTETE 64

Query: 85  RGHFYEGRGM--TIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPG 142
           +G  + G  M     T         G   L      GSL  ++  G +V +   I     
Sbjct: 65  KGASFTGPHMGAPYATMVEEALIAKGARTLLVFGWCGSLSTDLAIGDIVLVDGAI----A 120

Query: 143 TPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEI 202
                 N    GE F  +    D++ RA L       G     G   +  G   ET  ++
Sbjct: 121 DEGTSRNYMEPGEDFPRILP--DSDLRARLGNELSAGGIAFKSGTLWTTDGIYRETPKKV 178

Query: 203 RMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITN 239
              +  G   V M         R+  +++ A+  +++
Sbjct: 179 EFFRNRGAAGVDMECSALFAVGRYRKVRMAAILVVSD 215


>UniRef50_A9WPZ3 5'-methylthioadenosine phosphorylase n=1 Tax=Renibacterium
           salmoninarum ATCC 33209 RepID=A9WPZ3_RENSM
          Length = 160

 Score = 95.0 bits (235), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 23/112 (20%), Positives = 40/112 (35%), Gaps = 2/112 (1%)

Query: 156 RFFSLANAYDAEYRALLQKVAKEEGFPLTE-GVFVSYPGPNFETAAEIRMMQIIGGDVVG 214
           +    A+AY    R L+    +E   P    GV     GP F + AE   +   G +++ 
Sbjct: 2   QHIPAADAYCQTLRGLMVDSLRELAEPHQSTGVVAVINGPRFSSPAESAWLASAGCELIS 61

Query: 215 MSVVPEVISARHCDLKVVAVSAITNMAEG-LSDVKLSHAQTLAAAELSKQNF 265
           M+   E I A   +L    +  IT+   G      ++          ++   
Sbjct: 62  MTQYTEPILAAELNLGFATLCYITDADTGHDGSEPVTAQLVFERLRAAQPRI 113


>UniRef50_D1AJ63 Purine or other phosphorylase family 1 n=3 Tax=Bacteria
           RepID=D1AJ63_SEBTE
          Length = 249

 Score = 94.2 bits (233), Expect = 5e-18,   Method: Composition-based stats.
 Identities = 45/256 (17%), Positives = 91/256 (35%), Gaps = 34/256 (13%)

Query: 28  VAFIL--GSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGR 85
           V  I      +  L ++I+     +   +             E   G LQG  VV +K  
Sbjct: 21  VGIIGAMDKEVAGLKNEIKVKEIKNIGGI-------------EFYSGTLQGKDVVLLKSG 67

Query: 86  GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPM 145
                    T +   IR FK    + +  T  AG++  ++  G +V   D +     T  
Sbjct: 68  VGKVNSAMATDI--LIREFK---ADKIIFTGVAGAVNNKLNVGDVVISVDLVEHDFDT-- 120

Query: 146 VGLNDDRFGERFFSLANAY-DAEYRALLQKVAKEE--GFPLTEGVFVSYPGPNF-ETAAE 201
               +             Y D    +L +  A++      + +G   +  G  F    A+
Sbjct: 121 TAFGEKPGNVPGSDNGKFYADQSLISLAETSAQKVLGKTHVFKGTIAT--GDQFIADKAK 178

Query: 202 IRMMQ-IIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAEL 260
           +++++   G   V M        A    +  V + AI++ A+G     +++ +    +  
Sbjct: 179 VKVLEETFGAWAVEMEGASVAHVAALYKVPFVVIRAISDKADG--SAHVTYDEF---SNK 233

Query: 261 SKQNFINLICGFLRKI 276
           + +N I ++   L+K+
Sbjct: 234 AAENSIKIVNEMLKKM 249


>UniRef50_UPI000038263C COG0005: Purine nucleoside phosphorylase n=1 Tax=Magnetospirillum
           magnetotacticum MS-1 RepID=UPI000038263C
          Length = 162

 Score = 91.9 bits (227), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 38/134 (28%), Positives = 55/134 (41%), Gaps = 6/134 (4%)

Query: 10  PLFCIDIIKTYKPDFTPRVAFILGSGLGALADQI-ENAVAISYEKLPGFPVSTVHGHAGE 68
                D I          +A +LGSG G  A+ + E    +   ++PGF    V GH   
Sbjct: 22  ARAAADHIAQATGVEGHDMALVLGSGWGGAAELLGEVVAEVPTHEIPGFSAPAVAGHLSV 81

Query: 69  LVLGHLQG-----VPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRP 123
                ++         + +  R H YEG+G+  +   +RT    G E L  TN  G L  
Sbjct: 82  TRSIRVERADGSVRHALVLGSRTHLYEGKGVRAVVHGVRTAAATGAETLILTNGCGGLNQ 141

Query: 124 EVGAGSLVALKDHI 137
           E GAG+ V L  H+
Sbjct: 142 EWGAGTPVLLSXHM 155


>UniRef50_A0LI68 Purine and other phosphorylases, family 1 n=1 Tax=Syntrophobacter
           fumaroxidans MPOB RepID=A0LI68_SYNFM
          Length = 264

 Score = 88.8 bits (219), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 34/188 (18%), Positives = 58/188 (30%), Gaps = 14/188 (7%)

Query: 52  EKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCEL 111
            + P  P      +  +   G   GVP+  +          G       +     LG   
Sbjct: 53  SRFPQRPSMNNRIYLSDAYAGEYGGVPIALVG------PMLGAPQAVMVLEKMIALGVRK 106

Query: 112 LFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRAL 171
           +F     GSL+  V  G +V      +T         +    G+     +N    E R  
Sbjct: 107 VFAVGWCGSLQGRVSVGDVVVP----DTAVSEEGTSDHYPLGGDALRGPSN----ELRDS 158

Query: 172 LQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKV 231
           L       G  + EG   +   P  ET  ++   Q  G   V M     +  A    +++
Sbjct: 159 LIADLSARGVKVHEGSVWTTDAPYRETRRKVLQYQNSGVLAVDMETSALLTVAAFRQIRL 218

Query: 232 VAVSAITN 239
             V  +++
Sbjct: 219 AVVLTVSD 226


>UniRef50_A4GI77 Possible methylthioadenosine phosphorylase n=1 Tax=uncultured
           marine bacterium HF10_29C11 RepID=A4GI77_9BACT
          Length = 162

 Score = 88.4 bits (218), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 26/157 (16%), Positives = 51/157 (32%), Gaps = 9/157 (5%)

Query: 27  RVAFILGSGLGALADQIENA-VAISYEKLPGFPVSTVHGHAGELVLGHLQG---VPVVCM 82
           R+A I G+GL  +A     A   +       F V T +G+          G     +V +
Sbjct: 3   RLAIIGGTGLLNMATAQPFADADLEVLATDSFEVETPYGNVPLKSFQLQHGSSEKTLVFL 62

Query: 83  KGRGHF----YEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHIN 138
           +   +          +    + I   K    + +    + G L  +   G +     +I+
Sbjct: 63  QRHHNEGKPNKPPHNINHHAN-IWALKNANVDAILSVCSVGCLVQDFPPGRVGLADQYID 121

Query: 139 TMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKV 175
               T     ++  F         A +A    +L++V
Sbjct: 122 FTGQTTTFYDDEAEFTSVTVPFDRAMNASLELVLRQV 158


>UniRef50_A9B0R0 Methylthioadenosine phosphorylase n=1 Tax=Herpetosiphon aurantiacus
           ATCC 23779 RepID=A9B0R0_HERA2
          Length = 220

 Score = 87.3 bits (215), Expect = 6e-16,   Method: Composition-based stats.
 Identities = 20/149 (13%), Positives = 39/149 (26%), Gaps = 12/149 (8%)

Query: 90  EGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLN 149
           E         AI   K  G   +    +       +    ++     ++           
Sbjct: 33  EPNPHA----AIYAAKSQGVTWIIEAVSMLPCDGLLQPDDILIPDQLVDLTQQRSSTFFR 88

Query: 150 DDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLT-EGVFVSYPGPNFETAAEIRMMQII 208
           +  +G  F    + +  + RA L   A+     +   G          +T  E    Q  
Sbjct: 89  NRGYG--FIGQNSVWCPDLRASLLTAAQSISQRVFSRGTLAVGEA---DTTLE--AAQTW 141

Query: 209 GGDVVGMSVVPEVISARHCDLKVVAVSAI 237
               +  S  P    A+  +L    V  +
Sbjct: 142 QAHGLSRSAAPAAYLAKELELCYAVVGIV 170


>UniRef50_Q9ZMY2 MTA/SAH nucleosidase n=19 Tax=Proteobacteria RepID=MTNN_HELPJ
          Length = 230

 Score = 86.9 bits (214), Expect = 7e-16,   Method: Composition-based stats.
 Identities = 36/249 (14%), Positives = 81/249 (32%), Gaps = 35/249 (14%)

Query: 27  RVAFILGSGLGALADQIENAVA---ISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMK 83
           ++       LGA+ ++I   +    + +E++P      + G+      G      ++   
Sbjct: 3   KIGI-----LGAMREEITPILELFGVDFEEIP------LGGNV--FHKGVYHNKEIIVAY 49

Query: 84  ---GRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTM 140
              G+ H        I+          G + +  +  AGSL  ++    L+     +   
Sbjct: 50  SKIGKVHSTLTTTSMILAF--------GVQKVLFSGVAGSLVKDLKINDLLVATQLV--Q 99

Query: 141 PGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAA 200
               +   +         ++         AL +K+A E+   L EGV     G  F  + 
Sbjct: 100 HDVDLSAFDHPLGFIPESAIFIETSGSLNALAKKIANEQHIALKEGVIA--SGDQFVHSK 157

Query: 201 EIR--MMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAA 258
           E +  ++       V M         +   +    + +I++ A       +S  + L  +
Sbjct: 158 ERKEFLVSEFKASAVEMEGASVAFVCQKFGVPCCVLRSISDNA--DEKAGMSFDEFLEKS 215

Query: 259 ELSKQNFIN 267
             +   F+ 
Sbjct: 216 AHTSAKFLK 224


>UniRef50_A6Q4A9 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine
           nucleosidase n=50 Tax=Proteobacteria RepID=A6Q4A9_NITSB
          Length = 247

 Score = 84.9 bits (209), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 35/217 (16%), Positives = 74/217 (34%), Gaps = 26/217 (11%)

Query: 67  GELVLGHLQGVPVVCMKGR-GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEV 125
                   +G  ++    + G  Y      +    I+ FK    E L  +  AG++  ++
Sbjct: 48  NRYFEAKYKGHEIIVAYSKIGKVYASLTANV---LIQHFK---VEKLLFSGVAGAISEDL 101

Query: 126 GAGSLVALKDHINTMPGTPMVGLNDDRFGERF--FSLANAY---DAEYRALLQKVAKEEG 180
             G L+                L+   FG  +        Y   D   R + + VAK+  
Sbjct: 102 HIGDLI-------MAKRLCQHDLDITAFGHPYGYVPEGKVYVESDPVLREIAKDVAKQMQ 154

Query: 181 FPLTEGVFVSYPGPNF--ETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAIT 238
            PL EG   +  G  F  +   +  + +    D + M      +     D+    + +I+
Sbjct: 155 VPLKEGTIAT--GDQFIADPKRKEWIQKTFDADALEMEGAAVAVVCDAFDIPFFILRSIS 212

Query: 239 NMAEGLSDVKLSHAQTLA-AAELSKQNFINLICGFLR 274
           + A+   D        L  +++ S +  + ++   ++
Sbjct: 213 DAADM--DASFDFDTFLKSSSKRSAEFILKMVDAIIQ 247


>UniRef50_A0RR16 MTA/SAH nucleosidase n=2 Tax=Campylobacter RepID=A0RR16_CAMFF
          Length = 228

 Score = 83.8 bits (206), Expect = 5e-15,   Method: Composition-based stats.
 Identities = 35/170 (20%), Positives = 62/170 (36%), Gaps = 17/170 (10%)

Query: 108 GCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERF--FSLANAY- 164
           GCE+L  T  AG+L  ++  G ++           T    L+   FG  +      N Y 
Sbjct: 67  GCEILLFTGVAGALNEKLKIGDIL-------YATSTVQHDLDISAFGHPYGYVPGINVYE 119

Query: 165 --DAEYRALLQKVAKEEGFPLTEGVFVSYPGPNF--ETAAEIRMMQIIGGDVVGMSVVPE 220
             D +   + +KVA   G  L  GV     G  F  +   +  +      D V M     
Sbjct: 120 KTDEKLNNIAKKVAANNGVNLVSGVIA--SGDQFICDPIKKEWIKSTFDADAVEMEGASV 177

Query: 221 VISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLIC 270
                  D+    + AI++ A G +++       +  A  S +  ++++ 
Sbjct: 178 GQVCATLDIPYFLMRAISDEAGGGAEIDFD-KFVVEVANTSAKFVLDMVE 226


>UniRef50_C8QZD7 Purine or other phosphorylase family 1 n=1 Tax=Desulfurivibrio
           alkaliphilus AHT2 RepID=C8QZD7_9DELT
          Length = 247

 Score = 81.9 bits (201), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 37/193 (19%), Positives = 60/193 (31%), Gaps = 28/193 (14%)

Query: 48  AISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLL 107
              Y   PG   +T  G  G  + G   G PV  M                 A+     L
Sbjct: 49  WRRYSFFPGALHATPTG--GAWLAGPAVGAPVAVM-----------------ALEKLVAL 89

Query: 108 GCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAE 167
           G   +      G+L P V  G +V              +          F   + A D  
Sbjct: 90  GATAVISVGWCGALAPGVEVGDIVLPD---------TALSEEGTSAHYPFAGQSVAADPA 140

Query: 168 YRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHC 227
               LQ++    GF +  G   +   P  ET A++   +  G   V M        A + 
Sbjct: 141 LNLKLQRLLVGAGFTVHGGPVWTTDAPYRETWAKVARYRRRGILAVEMEFAALAAVAAYR 200

Query: 228 DLKVVAVSAITNM 240
            + + +V  ++++
Sbjct: 201 GVPLASVLLVSDL 213


>UniRef50_A9WPZ4 5'-methylthioadenosine phosphorylase n=1 Tax=Renibacterium
           salmoninarum ATCC 33209 RepID=A9WPZ4_RENSM
          Length = 121

 Score = 80.3 bits (197), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 25/116 (21%), Positives = 38/116 (32%), Gaps = 11/116 (9%)

Query: 17  IKTYKPDFTPRVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQG 76
           I + +    P V  I GSG+  L         I  +   G   + V        +  L G
Sbjct: 14  ISSDETQPRPVVGIIGGSGMYQLPGSRT-VQTIRLDTPFGQTSAPV-------TIAELDG 65

Query: 77  VPVVCMKGR--GHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSL 130
             V  +     GH    + +    + I     LG + +  + A GSL       SL
Sbjct: 66  QTVAFLPRHGGGHKVPPQQINYRAN-IWALASLGVKAIISSAAVGSLSASQPRDSL 120


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.313    0.151    0.416 

Lambda     K      H
   0.267   0.0465    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,657,014,851
Number of Sequences: 3077464
Number of extensions: 72821099
Number of successful extensions: 202483
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 709
Number of HSP's successfully gapped in prelim test: 341
Number of HSP's that attempted gapping in prelim test: 200124
Number of HSP's gapped (non-prelim): 1104
length of query: 277
length of database: 1,040,396,356
effective HSP length: 127
effective length of query: 150
effective length of database: 649,558,428
effective search space: 97433764200
effective search space used: 97433764200
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 92 (39.9 bits)
