Phyre 2 Results for P45563

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Email | l.a.kelley@imperial.ac.uk
Description | P45563
Date | Thu Jan 5 12:03:16 GMT 2012
Unique Job ID | 28abbde7ac7d287a

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c1yr3A_
Top template information
PDB header:transferase Chain: A: PDB Molecule:xanthosine phosphorylase; PDBTitle: escherichia coli purine nucleoside phosphorylase ii, the2 product of the xapa gene
Confidence and coverage
Confidence: | 100.0% | Coverage: | 99%
273 residues ( 99% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | S | Q | V | Q | F | S | H | N | P | L | F | C | I | D | I | I | K | T | Y | K | P | D | F | T | P | R | V | A | F | I | L | G | S | G | L | G | A | L | A | D | Q | I | E | N | A | V | A | I | S | Y | E | K | L | P | G | F | P | V | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? |  | ? |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | T | V | H | G | H | A | G | E | L | V | L | G | H | L | Q | G | V | P | V | V | C | M | K | G | R | G | H | F | Y | E | G | R | G | M | T | I | M | T | D | A | I | R | T | F | K | L | L | G | C | E | L | L | F | C | T | N | A | A | G | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | L | R | P | E | V | G | A | G | S | L | V | A | L | K | D | H | I | N | T | M | P | G | T | P | M | V | G | L | N | D | D | R | F | G | E | R | F | F | S | L | A | N | A | Y | D | A | E | Y | R | A | L | L | Q | K | V | A | K | E | E | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | F | P | L | T | E | G | V | F | V | S | Y | P | G | P | N | F | E | T | A | A | E | I | R | M | M | Q | I | I | G | G | D | V | V | G | M | S | V | V | P | E | V | I | S | A | R | H | C | D | L | K | V | V | A | V | S | A | I | T | N | M
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | .
Sequence |  | A | E | G | L | S | D | V | K | L | S | H | A | Q | T | L | A | A | A | E | L | S | K | Q | N | F | I | N | L | I | C | G | F | L | R | K | I | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c1yr3A_ |

### PDB 1yr3 chain A

Region: 5 - 277
Aligned: 273
Modelled: 273
Confidence: 100.0%
Identity: 100%
PDB header:transferase
Chain: A: PDB Molecule:xanthosine phosphorylase;
PDBTitle: escherichia coli purine nucleoside phosphorylase ii, the2 product of the xapa gene

Phyre2
2 |
| d3bgsa1 |

### PDB 3bgs chain A domain 1

Region: 1 - 276
Aligned: 275
Modelled: 276
Confidence: 100.0%
Identity: 41%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
3 |
| c2p4sA_ |

### PDB 2p4s chain A

Region: 11 - 276
Aligned: 265
Modelled: 266
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: A: PDB Molecule:purine nucleoside phosphorylase;
PDBTitle: structure of purine nucleoside phosphorylase from anopheles gambiae in2 complex with dadme-immh

Phyre2
4 |
| c3ggsA_ |

### PDB 3ggs chain A

Region: 9 - 276
Aligned: 267
Modelled: 268
Confidence: 100.0%
Identity: 41%
PDB header:transferase
Chain: A: PDB Molecule:purine nucleoside phosphorylase;
PDBTitle: human purine nucleoside phosphorylase double mutant e201q,n243d2 complexed with 2-fluoro-2'-deoxyadenosine

Phyre2
5 |
| d1g2oa_ |

### PDB 1g2o chain A

Region: 11 - 275
Aligned: 254
Modelled: 265
Confidence: 100.0%
Identity: 37%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
6 |
| c1tcvB_ |

### PDB 1tcv chain B

Region: 9 - 277
Aligned: 260
Modelled: 269
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: B: PDB Molecule:purine-nucleoside phosphorylase;
PDBTitle: crystal structure of the purine nucleoside phosphorylase2 from schistosoma mansoni in complex with non-detergent3 sulfobetaine 195 and acetate

Phyre2
7 |
| d1qe5a_ |

### PDB 1qe5 chain A

Region: 11 - 275
Aligned: 251
Modelled: 261
Confidence: 100.0%
Identity: 35%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
8 |
| d3pnpa_ |

### PDB 3pnp chain A

Region: 11 - 261
Aligned: 245
Modelled: 251
Confidence: 100.0%
Identity: 43%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
9 |
| c3khsB_ |

### PDB 3khs chain B

Region: 3 - 277
Aligned: 262
Modelled: 275
Confidence: 100.0%
Identity: 36%
PDB header:hydrolase
Chain: B: PDB Molecule:purine nucleoside phosphorylase;
PDBTitle: crystal structure of grouper iridovirus purine nucleoside2 phosphorylase

Phyre2
10 |
| d1vmka_ |

### PDB 1vmk chain A

Region: 11 - 275
Aligned: 243
Modelled: 265
Confidence: 100.0%
Identity: 36%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
11 |
| c3la8A_ |

### PDB 3la8 chain A

Region: 9 - 276
Aligned: 243
Modelled: 266
Confidence: 100.0%
Identity: 44%
PDB header:transferase
Chain: A: PDB Molecule:putative purine nucleoside phosphorylase;
PDBTitle: the crystal structure of smu.1229 from streptococcus mutans ua159

Phyre2
12 |
| c1wtaA_ |

### PDB 1wta chain A

Region: 20 - 277
Aligned: 244
Modelled: 258
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:5'-methylthioadenosine phosphorylase;
PDBTitle: crystal structure of 5'-deoxy-5'-methylthioadenosine from aeropyrum2 pernix (r32 form)

Phyre2
13 |
| d1cb0a_ |

### PDB 1cb0 chain A

Region: 26 - 277
Aligned: 239
Modelled: 252
Confidence: 100.0%
Identity: 25%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
14 |
| d1v4na_ |

### PDB 1v4n chain A

Region: 25 - 277
Aligned: 240
Modelled: 250
Confidence: 100.0%
Identity: 24%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
15 |
| c3ozbF_ |

### PDB 3ozb chain F

Region: 28 - 274
Aligned: 236
Modelled: 247
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: F: PDB Molecule:methylthioadenosine phosphorylase;
PDBTitle: crystal structure of 5'-methylthioinosine phosphorylase from2 psedomonas aeruginosa in complex with hypoxanthine

Phyre2
16 |
| d1rxya_ |

### PDB 1rxy chain A

Region: 25 - 273
Aligned: 220
Modelled: 236
Confidence: 100.0%
Identity: 15%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
17 |
| c3nm5B_ |

### PDB 3nm5 chain B

Region: 27 - 276
Aligned: 226
Modelled: 238
Confidence: 100.0%
Identity: 12%
PDB header:hydrolase
Chain: B: PDB Molecule:mta/sah nucleosidase;
PDBTitle: helicobacter pylori mtan complexed with formycin a

Phyre2
18 |
| c3qpbB_ |

### PDB 3qpb chain B

Region: 21 - 275
Aligned: 226
Modelled: 238
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: B: PDB Molecule:uridine phosphorylase;
PDBTitle: crystal structure of streptococcus pyogenes uridine phosphorylase2 reveals a subclass of the np-i superfamily

Phyre2
19 |
| c1nw4C_ |

### PDB 1nw4 chain C

Region: 26 - 277
Aligned: 225
Modelled: 243
Confidence: 100.0%
Identity: 15%
PDB header:transferase
Chain: C: PDB Molecule:uridine phosphorylase, putative;
PDBTitle: crystal structure of plasmodium falciparum purine nucleoside2 phosphorylase in complex with immh and sulfate

Phyre2
20 |
| d1q1ga_ |

### PDB 1q1g chain A

Region: 21 - 277
Aligned: 230
Modelled: 248
Confidence: 100.0%
Identity: 14%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c1yr3A_ |
|  | 100.0 | 100 | PDB header:transferase Chain: A: PDB Molecule:xanthosine phosphorylase; PDBTitle: escherichia coli purine nucleoside phosphorylase ii, the2 product of the xapa gene
2 | d3bgsa1 |
|  | 100.0 | 41 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
3 | c2p4sA_ |
|  | 100.0 | 40 | PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: structure of purine nucleoside phosphorylase from anopheles gambiae in2 complex with dadme-immh
4 | c3ggsA_ |
|  | 100.0 | 41 | PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: human purine nucleoside phosphorylase double mutant e201q,n243d2 complexed with 2-fluoro-2'-deoxyadenosine
5 | d1g2oa_ |
|  | 100.0 | 37 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
6 | c1tcvB_ |
|  | 100.0 | 40 | PDB header:transferase Chain: B: PDB Molecule:purine-nucleoside phosphorylase; PDBTitle: crystal structure of the purine nucleoside phosphorylase2 from schistosoma mansoni in complex with non-detergent3 sulfobetaine 195 and acetate
7 | d1qe5a_ |
|  | 100.0 | 35 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
8 | d3pnpa_ |
|  | 100.0 | 43 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
9 | c3khsB_ |
|  | 100.0 | 36 | PDB header:hydrolase Chain: B: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of grouper iridovirus purine nucleoside2 phosphorylase
10 | d1vmka_ |
|  | 100.0 | 36 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
11 | c3la8A_ |
|  | 100.0 | 44 | PDB header:transferase Chain: A: PDB Molecule:putative purine nucleoside phosphorylase; PDBTitle: the crystal structure of smu.1229 from streptococcus mutans ua159
12 | c1wtaA_ |
|  | 100.0 | 25 | PDB header:transferase Chain: A: PDB Molecule:5'-methylthioadenosine phosphorylase; PDBTitle: crystal structure of 5'-deoxy-5'-methylthioadenosine from aeropyrum2 pernix (r32 form)
13 | d1cb0a_ |
|  | 100.0 | 25 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
14 | d1v4na_ |
|  | 100.0 | 24 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
15 | c3ozbF_ |
|  | 100.0 | 25 | PDB header:transferase Chain: F: PDB Molecule:methylthioadenosine phosphorylase; PDBTitle: crystal structure of 5'-methylthioinosine phosphorylase from2 psedomonas aeruginosa in complex with hypoxanthine
16 | d1rxya_ |
|  | 100.0 | 15 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
17 | c3nm5B_ |
|  | 100.0 | 12 | PDB header:hydrolase Chain: B: PDB Molecule:mta/sah nucleosidase; PDBTitle: helicobacter pylori mtan complexed with formycin a
18 | c3qpbB_ |
|  | 100.0 | 17 | PDB header:transferase Chain: B: PDB Molecule:uridine phosphorylase; PDBTitle: crystal structure of streptococcus pyogenes uridine phosphorylase2 reveals a subclass of the np-i superfamily
19 | c1nw4C_ |
|  | 100.0 | 15 | PDB header:transferase Chain: C: PDB Molecule:uridine phosphorylase, putative; PDBTitle: crystal structure of plasmodium falciparum purine nucleoside2 phosphorylase in complex with immh and sulfate
20 | d1q1ga_ |
|  | 100.0 | 14 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
21 | c3mb8A_ |
| not modelled | 100.0 | 17 | PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of purine nucleoside phosphorylase from toxoplasma2 gondii in complex with immucillin-h
22 | d1je0a_ |
| not modelled | 100.0 | 15 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
23 | d1vhwa_ |
| not modelled | 100.0 | 13 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
24 | c1z34A_ |
| not modelled | 99.9 | 14 | PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of trichomonas vaginalis purine nucleoside2 phosphorylase complexed with 2-fluoro-2'-deoxyadenosine
25 | d1odka_ |
| not modelled | 99.9 | 17 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
26 | c3bl6A_ |
| not modelled | 99.9 | 14 | PDB header:hydrolase Chain: A: PDB Molecule:5'-methylthioadenosine nucleosidase/s- PDBTitle: crystal structure of staphylococcus aureus 5'-2 methylthioadenosine/s-adenosylhomocysteine nucleosidase in3 complex with formycin a
27 | d2ac7a1 |
| not modelled | 99.9 | 14 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
28 | c1zosE_ |
| not modelled | 99.9 | 14 | PDB header:hydrolase Chain: E: PDB Molecule:5'-methylthioadenosine / s-adenosylhomocysteine PDBTitle: structure of 5'-methylthionadenosine/s-adenosylhomocysteine2 nucleosidase from s. pneumoniae with a transition-state3 inhibitor mt-imma
29 | c3eeiA_ |
| not modelled | 99.9 | 17 | PDB header:hydrolase Chain: A: PDB Molecule:5-methylthioadenosine nucleosidase/s- PDBTitle: crystal structure of 5'-methylthioadenosine/s-2 adenosylhomocysteine nucleosidase from neisseria3 meningitidis in complex with methylthio-immucillin-a
30 | d1k9sa_ |
| not modelled | 99.9 | 13 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
31 | d1jysa_ |
| not modelled | 99.9 | 18 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
32 | d1ybfa_ |
| not modelled | 99.9 | 9 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
33 | c3tl6B_ |
| not modelled | 99.9 | 16 | PDB header:transferase Chain: B: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of purine nucleoside phosphorylase from entamoeba2 histolytica
34 | c3dp9A_ |
| not modelled | 99.9 | 14 | PDB header:hydrolase Chain: A: PDB Molecule:mta/sah nucleosidase; PDBTitle: crystal structure of vibrio cholerae 5'-methylthioadenosine/s-adenosyl2 homocysteine nucleosidase (mtan) complexed with butylthio-dadme-3 immucillin a
35 | c2h8gA_ |
| not modelled | 99.9 | 13 | PDB header:hydrolase Chain: A: PDB Molecule:5'-methylthioadenosine nucleosidase; PDBTitle: 5'-methylthioadenosine nucleosidase from arabidopsis2 thaliana
36 | c3bsfB_ |
| not modelled | 99.9 | 10 | PDB header:hydrolase Chain: B: PDB Molecule:at4g34840; PDBTitle: crystal structure of the mta/sah nucleosidase
37 | d1t8sa_ |
| not modelled | 99.8 | 15 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
38 | c2xrfA_ |
| not modelled | 99.8 | 15 | PDB header:transferase Chain: A: PDB Molecule:uridine phosphorylase 2; PDBTitle: crystal structure of human uridine phosphorylase 2
39 | c3eufC_ |
| not modelled | 99.8 | 15 | PDB header:transferase Chain: C: PDB Molecule:uridine phosphorylase 1; PDBTitle: crystal structure of bau-bound human uridine phosphorylase 1
40 | c3bjeA_ |
| not modelled | 99.7 | 14 | PDB header:transferase Chain: A: PDB Molecule:nucleoside phosphorylase, putative; PDBTitle: crystal structure of trypanosoma brucei nucleoside phosphorylase shows2 uridine phosphorylase activity
41 | d1oy0a_ |
| not modelled | 85.6 | 21 | Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Ketopantoate hydroxymethyltransferase PanB
42 | c2vdcF_ |
| not modelled | 83.6 | 9 | PDB header:oxidoreductase Chain: F: PDB Molecule:glutamate synthase [nadph] large chain; PDBTitle: the 9.5 a resolution structure of glutamate synthase from2 cryo-electron microscopy and its oligomerization behavior3 in solution: functional implications.
43 | c1lm1A_ |
| not modelled | 79.2 | 13 | PDB header:oxidoreductase Chain: A: PDB Molecule:ferredoxin-dependent glutamate synthase; PDBTitle: structural studies on the synchronization of catalytic centers in2 glutamate synthase: native enzyme
44 | d1y0ya2 |
| not modelled | 77.1 | 16 | Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases
45 | d1ea0a2 |
| not modelled | 58.6 | 10 | Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases
46 | c2greC_ |
| not modelled | 57.6 | 13 | PDB header:hydrolase Chain: C: PDB Molecule:deblocking aminopeptidase; PDBTitle: crystal structure of deblocking aminopeptidase from bacillus cereus
47 | d1o1xa_ |
| not modelled | 56.9 | 21 | Fold:Ribose/Galactose isomerase RpiB/AlsB Superfamily:Ribose/Galactose isomerase RpiB/AlsB Family:Ribose/Galactose isomerase RpiB/AlsB
48 | d1tg7a5 |
| not modelled | 55.5 | 20 | Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Glycosyl hydrolases family 35 catalytic domain
49 | c3fhkF_ |
| not modelled | 53.3 | 20 | PDB header:structural genomics, unknown function Chain: F: PDB Molecule:upf0403 protein yphp; PDBTitle: crystal structure of apc1446, b.subtilis yphp disulfide2 isomerase
50 | c3qd5B_ |
| not modelled | 52.9 | 29 | PDB header:isomerase Chain: B: PDB Molecule:putative ribose-5-phosphate isomerase; PDBTitle: crystal structure of a putative ribose-5-phosphate isomerase from2 coccidioides immitis solved by combined iodide ion sad and mr
51 | c2rjoA_ |
| not modelled | 52.3 | 24 | PDB header:signaling protein Chain: A: PDB Molecule:twin-arginine translocation pathway signal protein; PDBTitle: crystal structure of twin-arginine translocation pathway signal2 protein from burkholderia phytofirmans
52 | d1vixa1 |
| not modelled | 49.5 | 11 | Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases
53 | c2vk2A_ |
| not modelled | 46.9 | 13 | PDB header:transport protein Chain: A: PDB Molecule:abc transporter periplasmic-binding protein ytfq; PDBTitle: crystal structure of a galactofuranose binding protein
54 | c3he8A_ |
| not modelled | 43.5 | 29 | PDB header:isomerase Chain: A: PDB Molecule:ribose-5-phosphate isomerase; PDBTitle: structural study of clostridium thermocellum ribose-5-phosphate2 isomerase b
55 | d1twda_ |
| not modelled | 41.7 | 19 | Fold:TIM beta/alpha-barrel Superfamily:CutC-like Family:CutC-like
56 | d1nn4a_ |
| not modelled | 40.3 | 18 | Fold:Ribose/Galactose isomerase RpiB/AlsB Superfamily:Ribose/Galactose isomerase RpiB/AlsB Family:Ribose/Galactose isomerase RpiB/AlsB
57 | d2vvpa1 |
| not modelled | 35.6 | 32 | Fold:Ribose/Galactose isomerase RpiB/AlsB Superfamily:Ribose/Galactose isomerase RpiB/AlsB Family:Ribose/Galactose isomerase RpiB/AlsB
58 | c3czcA_ |
| not modelled | 34.6 | 33 | PDB header:transferase Chain: A: PDB Molecule:rmpb; PDBTitle: the crystal structure of a putative pts iib(ptxb) from2 streptococcus mutans
59 | c3thdD_ |
| not modelled | 33.1 | 21 | PDB header:hydrolase Chain: D: PDB Molecule:beta-galactosidase; PDBTitle: crystal structure of human beta-galactosidase in complex with 1-2 deoxygalactonojirimycin
60 | d2cx1a2 |
| not modelled | 31.6 | 25 | Fold:Cystatin-like Superfamily:Pre-PUA domain Family:Hypothetical protein APE0525, N-terminal domain
61 | c3k9cA_ |
| not modelled | 31.5 | 14 | PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, laci family protein; PDBTitle: crystal structure of laci transcriptional regulator from rhodococcus2 species.
62 | c3s81A_ |
| not modelled | 30.6 | 17 | PDB header:isomerase Chain: A: PDB Molecule:putative aspartate racemase; PDBTitle: crystal structure of putative aspartate racemase from salmonella2 typhimurium
63 | d2dria_ |
| not modelled | 30.3 | 18 | Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like
64 | c3onoA_ |
| not modelled | 30.3 | 17 | PDB header:isomerase Chain: A: PDB Molecule:ribose/galactose isomerase; PDBTitle: crystal structure of ribose-5-phosphate isomerase lacab_rpib from2 vibrio parahaemolyticus
65 | d1u9ya1 |
| not modelled | 29.6 | 12 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like
66 | c3d3aA_ |
| not modelled | 29.4 | 23 | PDB header:hydrolase Chain: A: PDB Molecule:beta-galactosidase; PDBTitle: crystal structure of a beta-galactosidase from bacteroides2 thetaiotaomicron
67 | c3fokH_ |
| not modelled | 29.3 | 16 | PDB header:structural genomics, unknown function Chain: H: PDB Molecule:uncharacterized protein cgl0159; PDBTitle: crystal structure of cgl0159 from corynebacterium2 glutamicum (brevibacterium flavum). northeast structural3 genomics target cgr115
68 | c1tvmA_ |
| not modelled | 28.5 | 8 | PDB header:transferase Chain: A: PDB Molecule:pts system, galactitol-specific iib component; PDBTitle: nmr structure of enzyme gatb of the galactitol-specific2 phosphoenolpyruvate-dependent phosphotransferase system
69 | c3d3qB_ |
| not modelled | 28.4 | 25 | PDB header:transferase Chain: B: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of trna delta(2)-isopentenylpyrophosphate2 transferase (se0981) from staphylococcus epidermidis.3 northeast structural genomics consortium target ser100
70 | d1on3a2 |
| not modelled | 28.0 | 15 | Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain
71 | c3iwpK_ |
| not modelled | 27.6 | 26 | PDB header:metal binding protein Chain: K: PDB Molecule:copper homeostasis protein cutc homolog; PDBTitle: crystal structure of human copper homeostasis protein cutc
72 | d1xnya2 |
| not modelled | 27.6 | 23 | Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain
73 | c3kl9F_ |
| not modelled | 27.4 | 13 | PDB header:hydrolase Chain: F: PDB Molecule:glutamyl aminopeptidase; PDBTitle: crystal structure of pepa from streptococcus pneumoniae
74 | d8abpa_ |
| not modelled | 27.2 | 19 | Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like
75 | d2pv7a2 |
| not modelled | 27.0 | 28 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
76 | d1fvia1 |
| not modelled | 24.0 | 36 | Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:DNA ligase/mRNA capping enzyme postcatalytic domain
77 | d1a9xa4 |
| not modelled | 23.2 | 9 | Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like
78 | c3ctpB_ |
| not modelled | 23.0 | 15 | PDB header:transcription regulator Chain: B: PDB Molecule:periplasmic binding protein/laci transcriptional regulator; PDBTitle: crystal structure of periplasmic binding protein/laci transcriptional2 regulator from alkaliphilus metalliredigens qymf complexed with d-3 xylulofuranose
79 | d1dkua1 |
| not modelled | 22.4 | 15 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like
80 | d1sv6a_ |
| not modelled | 21.8 | 26 | Fold:FAH Superfamily:FAH Family:FAH
81 | c3k7pA_ |
| not modelled | 21.8 | 21 | PDB header:isomerase Chain: A: PDB Molecule:ribose 5-phosphate isomerase; PDBTitle: structure of mutant of ribose 5-phosphate isomerase type b from2 trypanosoma cruzi.
82 | c3m1pA_ |
| not modelled | 21.8 | 21 | PDB header:isomerase Chain: A: PDB Molecule:ribose 5-phosphate isomerase; PDBTitle: structure of ribose 5-phosphate isomerase type b from trypanosoma2 cruzi, soaked with allose-6-phosphate
83 | c2ppwA_ |
| not modelled | 21.6 | 14 | PDB header:isomerase Chain: A: PDB Molecule:conserved domain protein; PDBTitle: the crystal structure of uncharacterized ribose 5-phosphate isomerase2 rpib from streptococcus pneumoniae
84 | d2a0ua1 |
| not modelled | 20.7 | 18 | Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like
85 | c1vkrA_ |
| not modelled | 20.6 | 17 | PDB header:transferase Chain: A: PDB Molecule:mannitol-specific pts system enzyme iiabc components; PDBTitle: structure of iib domain of the mannitol-specific permease enzyme ii
86 | d1vkra_ |
| not modelled | 20.6 | 17 | Fold:Phosphotyrosine protein phosphatases I-like Superfamily:PTS system IIB component-like Family:PTS system, Lactose/Cellobiose specific IIB subunit
87 | c2glfB_ |
| not modelled | 20.5 | 21 | PDB header:hydrolase Chain: B: PDB Molecule:probable m18-family aminopeptidase 1; PDBTitle: crystal structure of aminipeptidase (m18 family) from thermotoga2 maritima
88 | d2f9ya1 |
| not modelled | 19.6 | 14 | Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain
89 | c3exaD_ |
| not modelled | 19.5 | 28 | PDB header:transferase Chain: D: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of the full-length trna2 isopentenylpyrophosphate transferase (bh2366) from3 bacillus halodurans, northeast structural genomics4 consortium target bhr41.
90 | d2gpfa1 |
| not modelled | 19.4 | 24 | Fold:MbtH/L9 domain-like Superfamily:MbtH-like Family:MbtH-like
91 | d2pstx1 |
| not modelled | 19.4 | 24 | Fold:MbtH/L9 domain-like Superfamily:MbtH-like Family:MbtH-like
92 | d1jhda2 |
| not modelled | 19.1 | 40 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:ATP sulfurylase catalytic domain
93 | c2hjsA_ |
| not modelled | 18.9 | 29 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:usg-1 protein homolog; PDBTitle: the structure of a probable aspartate-semialdehyde dehydrogenase from2 pseudomonas aeruginosa
94 | c3u7vA_ |
| not modelled | 18.7 | 8 | PDB header:hydrolase Chain: A: PDB Molecule:beta-galactosidase; PDBTitle: the structure of a putative beta-galactosidase from caulobacter2 crescentus cb15.
95 | c2ioyB_ |
| not modelled | 18.2 | 18 | PDB header:sugar binding protein Chain: B: PDB Molecule:periplasmic sugar-binding protein; PDBTitle: crystal structure of thermoanaerobacter tengcongensis2 ribose binding protein
96 | c2qz9B_ |
| not modelled | 18.0 | 11 | PDB header:oxidoreductase Chain: B: PDB Molecule:aspartate-semialdehyde dehydrogenase; PDBTitle: crystal structure of aspartate semialdehyde dehydrogenase2 ii from vibrio cholerae
97 | c2zskA_ |
| not modelled | 17.4 | 18 | PDB header:unknown function Chain: A: PDB Molecule:226aa long hypothetical aspartate racemase; PDBTitle: crystal structure of ph1733, an aspartate racemase2 homologue, from pyrococcus horikoshii ot3
98 | d1umua_ |
| not modelled | 17.4 | 20 | Fold:LexA/Signal peptidase Superfamily:LexA/Signal peptidase Family:LexA-related
99 | c2gaaA_ |
| not modelled | 17.3 | 19 | PDB header:unknown function Chain: A: PDB Molecule:hypothetical 39.9 kda protein; PDBTitle: crystal structure of yfh7 from saccharomyces cerevisiae: a2 putative p-loop containing kinase with a circular3 permutation.

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0