Phyre 2 Results for P76096

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Email | l.a.kelley@imperial.ac.uk
Description | P76096
Date | Thu Jan 5 12:18:50 GMT 2012
Unique Job ID | 21ab7a63204e9efd

Summary |

Top model
Image coloured by rainbow N → C terminus
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Model (left) based on template d1k0ia2
Top template information
Fold:FAD-linked reductases, C-terminal domain Superfamily:FAD-linked reductases, C-terminal domain Family:PHBH-like
Confidence and coverage
Confidence: | 24.5% | Coverage: | 40%
22 residues ( 40% of your sequence) have been modelled with 24.5% confidence by the single highest scoring template.
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Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | .
Sequence |  | M | N | L | A | I | Q | I | L | A | S | Y | P | P | S | G | K | E | K | G | Y | E | A | Q | P | S | G | G | V | S | A | H | Y | L | H | Y | D | S | D | I | H | T | P | D | P | T | N | A | L | R | T | A | V | P | G | R
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? |  |  |  | ? |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d1k0ia2 |

### PDB 1k0i chain A domain 2

Region: 5 - 26
Aligned: 22
Modelled: 22
Confidence: 24.5%
Identity: 36%
Fold: FAD-linked reductases, C-terminal domain
Superfamily: FAD-linked reductases, C-terminal domain
Family: PHBH-like

Phyre2
2 |
| c3muwU_ |

### PDB 3muw chain U

Region: 11 - 53
Aligned: 40
Modelled: 41
Confidence: 15.7%
Identity: 30%
PDB header:virus
Chain: U: PDB Molecule:structural polyprotein;
PDBTitle: pseudo-atomic structure of the e2-e1 protein shell in sindbis virus

Phyre2
3 |
| c2jqoA_ |

### PDB 2jqo chain A

Region: 6 - 21
Aligned: 16
Modelled: 16
Confidence: 13.0%
Identity: 38%
PDB header:structural genomics
Chain: A: PDB Molecule:hypothetical protein yoba;
PDBTitle: nmr solution structure of bacillus subtilis yoba 21-120:2 northeast structural genomics consortium target sr547

Phyre2
4 |
| c2ldjA_ |

### PDB 2ldj chain A

Region: 2 - 16
Aligned: 15
Modelled: 15
Confidence: 11.7%
Identity: 53%
PDB header:de novo protein
Chain: A: PDB Molecule:trp-cage mini-protein;
PDBTitle: 1h chemical shift assignments and structure of trp-cage mini-protein2 with d-amino acid

Phyre2
5 |
| d1czan3 |

### PDB 1cza chain N domain 3

Region: 5 - 19
Aligned: 15
Modelled: 15
Confidence: 9.7%
Identity: 40%
Fold: Ribonuclease H-like motif
Superfamily: Actin-like ATPase domain
Family: Hexokinase

Phyre2
6 |
| c2ovfA_ |

### PDB 2ovf chain A

Region: 5 - 15
Aligned: 11
Modelled: 11
Confidence: 8.2%
Identity: 45%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:stal;
PDBTitle: crystal structure of stal-pap complex

Phyre2
7 |
| d1bg3a1 |

### PDB 1bg3 chain A domain 1

Region: 5 - 19
Aligned: 15
Modelled: 15
Confidence: 7.9%
Identity: 40%
Fold: Ribonuclease H-like motif
Superfamily: Actin-like ATPase domain
Family: Hexokinase

Phyre2
8 |
| d1v4sa1 |

### PDB 1v4s chain A domain 1

Region: 4 - 19
Aligned: 16
Modelled: 16
Confidence: 7.8%
Identity: 38%
Fold: Ribonuclease H-like motif
Superfamily: Actin-like ATPase domain
Family: Hexokinase

Phyre2
9 |
| d1bg3a3 |

### PDB 1bg3 chain A domain 3

Region: 5 - 19
Aligned: 15
Modelled: 15
Confidence: 7.0%
Identity: 40%
Fold: Ribonuclease H-like motif
Superfamily: Actin-like ATPase domain
Family: Hexokinase

Phyre2
10 |
| d1osya_ |

### PDB 1osy chain A

Region: 15 - 43
Aligned: 29
Modelled: 29
Confidence: 6.5%
Identity: 31%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Fungal immunomodulatory protein, FIP
Family: Fungal immunomodulatory protein, FIP

Phyre2
11 |
| d2j44a1 |

### PDB 2j44 chain A domain 1

Region: 20 - 38
Aligned: 19
Modelled: 19
Confidence: 6.4%
Identity: 42%
Fold: Prealbumin-like
Superfamily: Starch-binding domain-like
Family: PUD-like

Phyre2
12 |
| c2h8kA_ |

### PDB 2h8k chain A

Region: 7 - 15
Aligned: 9
Modelled: 9
Confidence: 6.3%
Identity: 78%
PDB header:transferase
Chain: A: PDB Molecule:sult1c3 splice variant d;
PDBTitle: human sulfotranferase sult1c3 in complex with pap

Phyre2
13 |
| d1ig8a1 |

### PDB 1ig8 chain A domain 1

Region: 5 - 19
Aligned: 15
Modelled: 15
Confidence: 6.3%
Identity: 40%
Fold: Ribonuclease H-like motif
Superfamily: Actin-like ATPase domain
Family: Hexokinase

Phyre2
14 |
| c2bh7A_ |

### PDB 2bh7 chain A

Region: 25 - 33
Aligned: 9
Modelled: 9
Confidence: 6.1%
Identity: 56%
PDB header:hydrolase
Chain: A: PDB Molecule:n-acetylmuramoyl-l-alanine amidase;
PDBTitle: crystal structure of a semet derivative of amid at 2.22 angstroms

Phyre2
15 |
| d1q44a_ |

### PDB 1q44 chain A

Region: 7 - 15
Aligned: 9
Modelled: 9
Confidence: 5.8%
Identity: 56%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: PAPS sulfotransferase

Phyre2
16 |
| c3f3hA_ |

### PDB 3f3h chain A

Region: 15 - 37
Aligned: 23
Modelled: 23
Confidence: 5.6%
Identity: 26%
PDB header:antitumor protein
Chain: A: PDB Molecule:immunomodulatory protein ling zhi-8;
PDBTitle: crystal structure and anti-tumor activity of lz-8 from the fungus2 ganoderma lucidium

Phyre2
17 |
| d1v58a2 |

### PDB 1v58 chain A domain 2

Region: 5 - 36
Aligned: 32
Modelled: 32
Confidence: 5.3%
Identity: 28%
Fold: Cystatin-like
Superfamily: DsbC/DsbG N-terminal domain-like
Family: DsbC/DsbG N-terminal domain-like

Phyre2
18 |
| d1xcra1 |

### PDB 1xcr chain A domain 1

Region: 27 - 43
Aligned: 13
Modelled: 17
Confidence: 5.3%
Identity: 77%
Fold: AF0104/ALDC/Ptd012-like
Superfamily: AF0104/ALDC/Ptd012-like
Family: PTD012-like

Phyre2
19 |
| d1czan1 |

### PDB 1cza chain N domain 1

Region: 5 - 19
Aligned: 15
Modelled: 15
Confidence: 5.3%
Identity: 40%
Fold: Ribonuclease H-like motif
Superfamily: Actin-like ATPase domain
Family: Hexokinase

Phyre2

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d1k0ia2 |
|  | 24.5 | 36 | Fold:FAD-linked reductases, C-terminal domain Superfamily:FAD-linked reductases, C-terminal domain Family:PHBH-like
2 | c3muwU_ |
|  | 15.7 | 30 | PDB header:virus Chain: U: PDB Molecule:structural polyprotein; PDBTitle: pseudo-atomic structure of the e2-e1 protein shell in sindbis virus
3 | c2jqoA_ |
|  | 13.0 | 38 | PDB header:structural genomics Chain: A: PDB Molecule:hypothetical protein yoba; PDBTitle: nmr solution structure of bacillus subtilis yoba 21-120:2 northeast structural genomics consortium target sr547
4 | c2ldjA_ |
|  | 11.7 | 53 | PDB header:de novo protein Chain: A: PDB Molecule:trp-cage mini-protein; PDBTitle: 1h chemical shift assignments and structure of trp-cage mini-protein2 with d-amino acid
5 | d1czan3 |
|  | 9.7 | 40 | Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Hexokinase
6 | c2ovfA_ |
|  | 8.2 | 45 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:stal; PDBTitle: crystal structure of stal-pap complex
7 | d1bg3a1 |
|  | 7.9 | 40 | Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Hexokinase
8 | d1v4sa1 |
|  | 7.8 | 38 | Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Hexokinase
9 | d1bg3a3 |
|  | 7.0 | 40 | Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Hexokinase
10 | d1osya_ |
|  | 6.5 | 31 | Fold:Immunoglobulin-like beta-sandwich Superfamily:Fungal immunomodulatory protein, FIP Family:Fungal immunomodulatory protein, FIP
11 | d2j44a1 |
|  | 6.4 | 42 | Fold:Prealbumin-like Superfamily:Starch-binding domain-like Family:PUD-like
12 | c2h8kA_ |
|  | 6.3 | 78 | PDB header:transferase Chain: A: PDB Molecule:sult1c3 splice variant d; PDBTitle: human sulfotranferase sult1c3 in complex with pap
13 | d1ig8a1 |
|  | 6.3 | 40 | Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Hexokinase
14 | c2bh7A_ |
|  | 6.1 | 56 | PDB header:hydrolase Chain: A: PDB Molecule:n-acetylmuramoyl-l-alanine amidase; PDBTitle: crystal structure of a semet derivative of amid at 2.22 angstroms
15 | d1q44a_ |
|  | 5.8 | 56 | Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:PAPS sulfotransferase
16 | c3f3hA_ |
|  | 5.6 | 26 | PDB header:antitumor protein Chain: A: PDB Molecule:immunomodulatory protein ling zhi-8; PDBTitle: crystal structure and anti-tumor activity of lz-8 from the fungus2 ganoderma lucidium
17 | d1v58a2 |
|  | 5.3 | 28 | Fold:Cystatin-like Superfamily:DsbC/DsbG N-terminal domain-like Family:DsbC/DsbG N-terminal domain-like
18 | d1xcra1 |
|  | 5.3 | 77 | Fold:AF0104/ALDC/Ptd012-like Superfamily:AF0104/ALDC/Ptd012-like Family:PTD012-like
19 | d1czan1 |
|  | 5.3 | 40 | Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Hexokinase

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0