Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	F	S	V	K	S	G	S	P	E	K	Q	R	S	A	C	I	V	V	G	V	F	E	P	R	R	L	S	P	I	A	E	Q	L	D	K	I	S	D	G	Y	I	S	A	L	L	R	R	G	E	L	E	G	K	P	G	Q	T	L
Secondary structure
SS confidence
Disorder		?	?					?		?	?																?	?	?	?		?																			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	L	H	H	V	P	N	V	L	S	E	R	I	L	L	I	G	C	G	K	E	R	E	L	D	E	R	Q	Y	K	Q	V	I	Q	K	T	I	N	T	L	N	D	T	G	S	M	E	A	V	C	F	L	T	E	L	H	V	K	G	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		N	N	Y	W	K	V	R	Q	A	V	E	T	A	K	E	T	L	Y	S	F	D	Q	L	K	T	N	K	S	E	P	R	R	P	L	R	K	M	V	F	N	V	P	T	R	R	E	L	T	S	G	E	R	A	I	Q	H	G	L	A	I
Secondary structure
SS confidence
Disorder																								?	?	?		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	A	G	I	K	A	A	K	D	L	G	N	M	P	P	N	I	C	N	A	A	Y	L	A	S	Q	A	R	Q	L	A	D	S	Y	S	K	N	V	I	T	R	V	I	G	E	Q	Q	M	K	E	L	G	M	H	S	Y	L	A	V	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		Q	G	S	Q	N	E	S	L	M	S	V	I	E	Y	K	G	N	A	S	E	D	A	R	P	I	V	L	V	G	K	G	L	T	F	D	S	G	G	I	S	I	K	P	S	E	G	M	D	E	M	K	Y	D	M	C	G	A	A	A	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		Y	G	V	M	R	M	V	A	E	L	Q	L	P	I	N	V	I	G	V	L	A	G	C	E	N	M	P	G	G	R	A	Y	R	P	G	D	V	L	T	T	M	S	G	Q	T	V	E	V	L	N	T	D	A	E	G	R	L	V	L	C
Secondary structure
SS confidence
Disorder																															?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		D	V	L	T	Y	V	E	R	F	E	P	E	A	V	I	D	V	A	T	L	T	G	A	C	V	I	A	L	G	H	H	I	T	G	L	M	A	N	H	N	P	L	A	H	E	L	I	A	A	S	E	Q	S	G	D	R	A	W	R	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		P	L	G	D	E	Y	Q	E	Q	L	E	S	N	F	A	D	M	A	N	I	G	G	R	P	G	G	A	I	T	A	G	C	F	L	S	R	F	T	R	K	Y	N	W	A	H	L	D	I	A	G	T	A	W	R	S	G	K	A	K	G
Secondary structure
SS confidence
Disorder																									?	?																													?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.
Sequence		A	T	G	R	P	V	A	L	L	A	Q	F	L	L	N	R	A	G	F	N	G	E	E
Secondary structure
SS confidence
Disorder																			?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1gyt chain G Region: 1 - 503 Aligned: 503 Modelled: 503 Confidence: 100.0% Identity: 100% PDB header:hydrolase Chain: G: PDB Molecule:cytosol aminopeptidase; PDBTitle: e. coli aminopeptidase a (pepa) Phyre2 PDB 3h8g chain C Region: 1 - 498 Aligned: 494 Modelled: 498 Confidence: 100.0% Identity: 54% PDB header:hydrolase Chain: C: PDB Molecule:cytosol aminopeptidase; PDBTitle: bestatin complex structure of leucine aminopeptidase from pseudomonas2 putida Phyre2 PDB 3jru chain B Region: 1 - 498 Aligned: 488 Modelled: 498 Confidence: 100.0% Identity: 49% PDB header:hydrolase Chain: B: PDB Molecule:probable cytosol aminopeptidase; PDBTitle: crystal structure of leucyl aminopeptidase (pepa) from xoo0834,2 xanthomonas oryzae pv. oryzae kacc10331 Phyre2 PDB 3kzw chain D Region: 1 - 496 Aligned: 485 Modelled: 490 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: D: PDB Molecule:cytosol aminopeptidase; PDBTitle: crystal structure of cytosol aminopeptidase from staphylococcus aureus2 col Phyre2 PDB 1lan chain A Region: 15 - 499 Aligned: 464 Modelled: 481 Confidence: 100.0% Identity: 34% PDB header:hydrolase (alpha-aminoacylpeptide) Chain: A: PDB Molecule:leucine aminopeptidase; PDBTitle: leucine aminopeptidase complex with l-leucinal Phyre2 PDB 3kr5 chain E Region: 5 - 495 Aligned: 473 Modelled: 482 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: E: PDB Molecule:m17 leucyl aminopeptidase; PDBTitle: structure of a protease 4 Phyre2 PDB 3pei chain A Region: 20 - 500 Aligned: 450 Modelled: 464 Confidence: 100.0% Identity: 41% PDB header:hydrolase Chain: A: PDB Molecule:cytosol aminopeptidase; PDBTitle: crystal structure of cytosol aminopeptidase from francisella2 tularensis Phyre2 PDB 3ij3 chain A Region: 28 - 498 Aligned: 435 Modelled: 441 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: A: PDB Molecule:cytosol aminopeptidase; PDBTitle: 1.8 angstrom resolution crystal structure of cytosol aminopeptidase2 from coxiella burnetii Phyre2 PDB 1gyt chain A domain 2 Region: 179 - 503 Aligned: 325 Modelled: 325 Confidence: 100.0% Identity: 100% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: Leucine aminopeptidase, C-terminal domain Phyre2 PDB 2hc9 chain A Region: 2 - 497 Aligned: 474 Modelled: 487 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:leucine aminopeptidase 1; PDBTitle: structure of caenorhabditis elegans leucine aminopeptidase-zinc2 complex (lap1) Phyre2 PDB 1lam chain A domain 1 Region: 180 - 498 Aligned: 319 Modelled: 319 Confidence: 100.0% Identity: 42% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: Leucine aminopeptidase, C-terminal domain Phyre2 PDB 1gyt chain A domain 1 Region: 1 - 177 Aligned: 177 Modelled: 177 Confidence: 99.9% Identity: 100% Fold: Macro domain-like Superfamily: Macro domain-like Family: Leucine aminopeptidase (Aminopeptidase A), N-terminal domain Phyre2 PDB 1lam chain A domain 2 Region: 17 - 174 Aligned: 141 Modelled: 152 Confidence: 99.7% Identity: 18% Fold: Macro domain-like Superfamily: Macro domain-like Family: Leucine aminopeptidase (Aminopeptidase A), N-terminal domain Phyre2 PDB 3rza chain A Region: 182 - 328 Aligned: 137 Modelled: 147 Confidence: 95.9% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:tripeptidase; PDBTitle: crystal structure of a tripeptidase (sav1512) from staphylococcus2 aureus subsp. aureus mu50 at 2.10 a resolution Phyre2 PDB 1vhe chain A domain 2 Region: 182 - 324 Aligned: 119 Modelled: 129 Confidence: 95.6% Identity: 15% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: Bacterial dinuclear zinc exopeptidases Phyre2 PDB 2dx6 chain B Region: 2 - 134 Aligned: 131 Modelled: 133 Confidence: 93.9% Identity: 13% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein ttha0132; PDBTitle: crystal structure of conserved hypothetical protein, ttha0132 from2 thermus thermophilus hb8 Phyre2 PDB 3ct9 chain B Region: 178 - 333 Aligned: 133 Modelled: 154 Confidence: 93.2% Identity: 10% PDB header:hydrolase Chain: B: PDB Molecule:acetylornithine deacetylase; PDBTitle: crystal structure of a putative zinc peptidase (np_812461.1) from2 bacteroides thetaiotaomicron vpi-5482 at 2.31 a resolution Phyre2 PDB 2gre chain A domain 2 Region: 182 - 337 Aligned: 109 Modelled: 119 Confidence: 92.8% Identity: 17% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: Bacterial dinuclear zinc exopeptidases Phyre2 PDB 3q71 chain A Region: 1 - 176 Aligned: 168 Modelled: 176 Confidence: 91.6% Identity: 8% PDB header:transferase Chain: A: PDB Molecule:poly [adp-ribose] polymerase 14; PDBTitle: human parp14 (artd8) - macro domain 2 in complex with adenosine-5-2 diphosphoribose Phyre2 PDB 1cg2 chain A domain 1 Region: 178 - 324 Aligned: 125 Modelled: 127 Confidence: 91.4% Identity: 14% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: Bacterial dinuclear zinc exopeptidases Phyre2 1 c1gytG_ 2 c3h8gC_ 3 c3jruB_ 4 c3kzwD_ 5 c1lanA_ 6 c3kr5E_ 7 c3peiA_ 8 c3ij3A_ 9 d1gyta2 10 c2hc9A_ 11 d1lama1 12 d1gyta1 13 d1lama2 14 c3rzaA_ 15 d1vhea2 16 c2dx6B_ 17 c3ct9B_ 18 d2grea2 19 c3q71A_ 20 d1cg2a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1gytG_ 100.0 100 PDB header:hydrolase Chain: G: PDB Molecule:cytosol aminopeptidase; PDBTitle: e. coli aminopeptidase a (pepa) 2 c3h8gC_ 100.0 54 PDB header:hydrolase Chain: C: PDB Molecule:cytosol aminopeptidase; PDBTitle: bestatin complex structure of leucine aminopeptidase from pseudomonas2 putida 3 c3jruB_ 100.0 49 PDB header:hydrolase Chain: B: PDB Molecule:probable cytosol aminopeptidase; PDBTitle: crystal structure of leucyl aminopeptidase (pepa) from xoo0834,2 xanthomonas oryzae pv. oryzae kacc10331 4 c3kzwD_ 100.0 29 PDB header:hydrolase Chain: D: PDB Molecule:cytosol aminopeptidase; PDBTitle: crystal structure of cytosol aminopeptidase from staphylococcus aureus2 col 5 c1lanA_ 100.0 34 PDB header:hydrolase (alpha-aminoacylpeptide) Chain: A: PDB Molecule:leucine aminopeptidase; PDBTitle: leucine aminopeptidase complex with l-leucinal 6 c3kr5E_ 100.0 30 PDB header:hydrolase Chain: E: PDB Molecule:m17 leucyl aminopeptidase; PDBTitle: structure of a protease 4 7 c3peiA_ 100.0 41 PDB header:hydrolase Chain: A: PDB Molecule:cytosol aminopeptidase; PDBTitle: crystal structure of cytosol aminopeptidase from francisella2 tularensis 8 c3ij3A_ 100.0 30 PDB header:hydrolase Chain: A: PDB Molecule:cytosol aminopeptidase; PDBTitle: 1.8 angstrom resolution crystal structure of cytosol aminopeptidase2 from coxiella burnetii 9 d1gyta2 100.0 100 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Leucine aminopeptidase, C-terminal domain 10 c2hc9A_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:leucine aminopeptidase 1; PDBTitle: structure of caenorhabditis elegans leucine aminopeptidase-zinc2 complex (lap1) 11 d1lama1 100.0 42 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Leucine aminopeptidase, C-terminal domain 12 d1gyta1 99.9 100 Fold:Macro domain-like Superfamily:Macro domain-like Family:Leucine aminopeptidase (Aminopeptidase A), N-terminal domain 13 d1lama2 99.7 18 Fold:Macro domain-like Superfamily:Macro domain-like Family:Leucine aminopeptidase (Aminopeptidase A), N-terminal domain 14 c3rzaA_ 95.9 12 PDB header:hydrolase Chain: A: PDB Molecule:tripeptidase; PDBTitle: crystal structure of a tripeptidase (sav1512) from staphylococcus2 aureus subsp. aureus mu50 at 2.10 a resolution 15 d1vhea2 95.6 15 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 16 c2dx6B_ 93.9 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein ttha0132; PDBTitle: crystal structure of conserved hypothetical protein, ttha0132 from2 thermus thermophilus hb8 17 c3ct9B_ 93.2 10 PDB header:hydrolase Chain: B: PDB Molecule:acetylornithine deacetylase; PDBTitle: crystal structure of a putative zinc peptidase (np_812461.1) from2 bacteroides thetaiotaomicron vpi-5482 at 2.31 a resolution 18 d2grea2 92.8 17 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 19 c3q71A_ 91.6 8 PDB header:transferase Chain: A: PDB Molecule:poly [adp-ribose] polymerase 14; PDBTitle: human parp14 (artd8) - macro domain 2 in complex with adenosine-5-2 diphosphoribose 20 d1cg2a1 91.4 14 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 21 c3t6mA_ not modelled 91.1 12 PDB header:hydrolase Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of the catalytic domain of dape protein from2 v.cholerea in the zn bound form 22 d1yloa2 not modelled 90.1 16 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 23 d1spva_ not modelled 87.8 10 Fold:Macro domain-like Superfamily:Macro domain-like Family:Macro domain 24 d1vgya1 not modelled 86.5 10 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 25 d1yd9a1 not modelled 85.9 7 Fold:Macro domain-like Superfamily:Macro domain-like Family:Macro domain 26 c2q43A_ not modelled 85.7 11 PDB header:hydrolase Chain: A: PDB Molecule:iaa-amino acid hydrolase ilr1-like 2; PDBTitle: ensemble refinement of the protein crystal structure of iaa-aminoacid2 hydrolase from arabidopsis thaliana gene at5g56660 27 c3kh6A_ not modelled 85.6 10 PDB header:transferase Chain: A: PDB Molecule:poly [adp-ribose] polymerase 15; PDBTitle: human poly(adp-ribose) polymerase 15, macro domain 2 in2 complex with adenosine-5-diphosphoribose 28 c3gb0A_ not modelled 84.6 11 PDB header:hydrolase Chain: A: PDB Molecule:peptidase t; PDBTitle: crystal structure of aminopeptidase pept (np_980509.1) from bacillus2 cereus atcc 10987 at 2.04 a resolution 29 d1vhoa2 not modelled 83.8 11 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 30 c3pfoB_ not modelled 83.5 9 PDB header:hydrolase Chain: B: PDB Molecule:putative acetylornithine deacetylase; PDBTitle: crystal structure of a putative acetylornithine deacetylase (rpa2325)2 from rhodopseudomonas palustris cga009 at 1.90 a resolution 31 c3q6zA_ not modelled 80.0 12 PDB header:transferase Chain: A: PDB Molecule:poly [adp-ribose] polymerase 14; PDBTitle: human parp14 (artd8)-macro domain 1 in complex with adenosine-5-2 diphosphoribose 32 d1zr5a1 not modelled 78.8 8 Fold:Macro domain-like Superfamily:Macro domain-like Family:Macro domain 33 d2fvga2 not modelled 78.3 11 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 34 d2hgaa1 not modelled 78.0 16 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:MTH1368 C-terminal domain-like 35 c1q7lA_ not modelled 77.1 9 PDB header:hydrolase Chain: A: PDB Molecule:aminoacylase-1; PDBTitle: zn-binding domain of the t347g mutant of human aminoacylase-2 i 36 c3ejfA_ not modelled 76.3 12 PDB header:hydrolase Chain: A: PDB Molecule:non-structural protein 3; PDBTitle: crystal structure of ibv x-domain at ph 8.5 37 c2x47A_ not modelled 73.4 9 PDB header:signaling protein Chain: A: PDB Molecule:macro domain-containing protein 1; PDBTitle: crystal structure of human macrod1 38 c2qyvB_ not modelled 71.7 12 PDB header:hydrolase Chain: B: PDB Molecule:xaa-his dipeptidase; PDBTitle: crystal structure of putative xaa-his dipeptidase (yp_718209.1) from2 haemophilus somnus 129pt at 2.11 a resolution 39 c2xd7B_ not modelled 70.9 10 PDB header:dna-binding protein Chain: B: PDB Molecule:core histone macro-h2a.2; PDBTitle: crystal structure of the macro domain of human core histone2 h2a 40 c1vgyB_ not modelled 70.6 9 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of succinyl diaminopimelate desuccinylase 41 d1xmba1 not modelled 69.7 11 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 42 c3mruB_ not modelled 69.3 16 PDB header:hydrolase Chain: B: PDB Molecule:aminoacyl-histidine dipeptidase; PDBTitle: crystal structure of aminoacylhistidine dipeptidase from vibrio2 alginolyticus 43 c1zr5B_ not modelled 66.4 7 PDB header:gene regulation Chain: B: PDB Molecule:h2afy protein; PDBTitle: crystal structure of the macro-domain of human core histone variant2 macroh2a1.2 44 c3i18A_ not modelled 63.4 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lmo2051 protein; PDBTitle: crystal structure of the pdz domain of the sdrc-like protein2 (lmo2051) from listeria monocytogenes, northeast structural3 genomics consortium target lmr166b 45 c2pokB_ not modelled 62.9 16 PDB header:hydrolase Chain: B: PDB Molecule:peptidase, m20/m25/m40 family; PDBTitle: crystal structure of a m20 family metallo peptidase from streptococcus2 pneumoniae 46 d1sota1 not modelled 62.3 17 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 47 c1ysjB_ not modelled 60.6 12 PDB header:hydrolase Chain: B: PDB Molecule:protein yxep; PDBTitle: crystal structure of bacillus subtilis yxep protein (apc1829), a2 dinuclear metal binding peptidase from m20 family 48 c2p3wB_ not modelled 57.6 27 PDB header:protein binding Chain: B: PDB Molecule:probable serine protease htra3; PDBTitle: crystal structure of the htra3 pdz domain bound to a phage-derived2 ligand (fgrwv) 49 c1vhoA_ not modelled 57.5 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:endoglucanase; PDBTitle: crystal structure of a putative peptidase/endoglucanase 50 c2greC_ not modelled 56.9 18 PDB header:hydrolase Chain: C: PDB Molecule:deblocking aminopeptidase; PDBTitle: crystal structure of deblocking aminopeptidase from bacillus cereus 51 d1vhua_ not modelled 55.7 11 Fold:Macro domain-like Superfamily:Macro domain-like Family:Macro domain 52 c2kl1A_ not modelled 55.3 27 PDB header:protein binding Chain: A: PDB Molecule:ylbl protein; PDBTitle: solution structure of gtr34c from geobacillus thermodenitrificans.2 northeast structural genomics consortium target gtr34c 53 d2z9ia1 not modelled 54.0 13 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 54 d1ky9a1 not modelled 53.9 27 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 55 d1ky9b2 not modelled 50.4 25 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 56 c2kjpA_ not modelled 49.5 28 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein ylbl; PDBTitle: solution structure of protein ylbl (bsu15050) from bacillus2 subtilis, northeast structural genomics consortium target3 sr713a 57 c2joaA_ not modelled 49.4 19 PDB header:protein binding Chain: A: PDB Molecule:serine protease htra1; PDBTitle: htra1 bound to an optimized peptide: nmr assignment of pdz2 domain and ligand resonances 58 d1mfga_ not modelled 47.5 23 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 59 d1lcya1 not modelled 47.0 32 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 60 c3tc8A_ not modelled 45.9 15 PDB header:hydrolase Chain: A: PDB Molecule:leucine aminopeptidase; PDBTitle: crystal structure of a hypothetical zn-dependent exopeptidase2 (bdi_3547) from parabacteroides distasonis atcc 8503 at 1.06 a3 resolution 61 c3pv4A_ not modelled 45.8 23 PDB header:hydrolase Chain: A: PDB Molecule:degq; PDBTitle: structure of legionella fallonii degq (delta-pdz2 variant) 62 c2zplA_ not modelled 45.0 24 PDB header:hydrolase Chain: A: PDB Molecule:regulator of sigma e protease; PDBTitle: crystal structure analysis of pdz domain a 63 c2r3yC_ not modelled 44.1 13 PDB header:hydrolase/hydrolase activator Chain: C: PDB Molecule:protease degs; PDBTitle: crystal structure of the degs protease in complex with the2 ywf activating peptide 64 c1ky9A_ not modelled 43.9 26 PDB header:hydrolase Chain: A: PDB Molecule:protease do; PDBTitle: crystal structure of degp (htra) 65 d2i4sa1 not modelled 43.1 20 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:EpsC C-terminal domain-like 66 d2h3la1 not modelled 42.6 23 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 67 c2eguA_ not modelled 42.4 16 PDB header:transferase Chain: A: PDB Molecule:cysteine synthase; PDBTitle: crystal structure of o-acetylserine sulfhydrase from geobacillus2 kaustophilus hta426 68 d2i6va1 not modelled 42.0 20 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:EpsC C-terminal domain-like 69 d1fnoa4 not modelled 41.0 13 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 70 c3bpuA_ not modelled 40.6 18 PDB header:transferase Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz domain- PDBTitle: crystal structure of the 3rd pdz domain of human membrane associated2 guanylate kinase, c677s and c709s double mutant 71 d1ysja1 not modelled 40.0 13 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 72 c1lcyA_ not modelled 39.9 33 PDB header:hydrolase Chain: A: PDB Molecule:htra2 serine protease; PDBTitle: crystal structure of the mitochondrial serine protease htra2 73 d1z2la1 not modelled 39.5 18 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 74 d1ed7a_ not modelled 39.3 40 Fold:WW domain-like Superfamily:Carbohydrate binding domain Family:Carbohydrate binding domain 75 d2w6ka1 not modelled 38.9 8 Fold:CobE/GbiG C-terminal domain-like Superfamily:CobE/GbiG C-terminal domain-like Family:CobE/GbiG C-terminal domain-like 76 c1vheA_ not modelled 38.0 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:aminopeptidase/glucanase homolog; PDBTitle: crystal structure of a aminopeptidase/glucanase homolog 77 d1fc6a3 not modelled 38.0 37 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:Tail specific protease PDZ domain 78 c2fvgA_ not modelled 36.5 11 PDB header:hydrolase Chain: A: PDB Molecule:endoglucanase; PDBTitle: crystal structure of endoglucanase (tm1049) from thermotoga maritima2 at 2.01 a resolution 79 c3tx8A_ not modelled 36.3 10 PDB header:hydrolase Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of a succinyl-diaminopimelate desuccinylase (arge)2 from corynebacterium glutamicum atcc 13032 at 2.97 a resolution 80 c3d5bD_ not modelled 35.3 21 PDB header:ribosome Chain: D: PDB Molecule:50s ribosomal protein l2; PDBTitle: structural basis for translation termination on the 70s ribosome. this2 file contains the 50s subunit of one 70s ribosome. the entire crystal3 structure contains two 70s ribosomes as described in remark 400. 81 d1sroa_ not modelled 34.5 36 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 82 c3ramC_ not modelled 34.3 11 PDB header:hydrolase Chain: C: PDB Molecule:hmra protein; PDBTitle: crystal structure of hmra 83 c3l4fD_ not modelled 32.5 32 PDB header:signaling protein/protein binding Chain: D: PDB Molecule:sh3 and multiple ankyrin repeat domains protein PDBTitle: crystal structure of betapix coiled-coil domain and shank2 pdz complex 84 c3stjC_ not modelled 32.2 20 PDB header:hydrolase Chain: C: PDB Molecule:protease degq; PDBTitle: crystal structure of the protease + pdz1 domain of degq from2 escherichia coli 85 d1xfoa2 not modelled 31.8 10 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 86 c3pv5B_ not modelled 31.1 20 PDB header:hydrolase Chain: B: PDB Molecule:degq; PDBTitle: structure of legionella fallonii degq (n189g/p190g variant) 87 c3gqhB_ not modelled 30.6 21 PDB header:viral protein Chain: B: PDB Molecule:preneck appendage protein; PDBTitle: crystal structure of the bacteriophage phi29 gene product2 12 c-terminal fragment 88 c2zpmA_ not modelled 30.5 20 PDB header:hydrolase Chain: A: PDB Molecule:regulator of sigma e protease; PDBTitle: crystal structure analysis of pdz domain b 89 c3fj1A_ not modelled 30.4 17 PDB header:isomerase Chain: A: PDB Molecule:putative phosphosugar isomerase; PDBTitle: crystal structure of putative phosphosugar isomerase (yp_167080.1)2 from silicibacter pomeroyi dss-3 at 1.75 a resolution 90 c3gdsA_ not modelled 30.1 12 PDB header:hydrolase/hydrolase activator Chain: A: PDB Molecule:protease degs; PDBTitle: crystal structure of degs h198p/d320a mutant modified by dfp in2 complex with dnrdgnvyyf peptide 91 c3pc3A_ not modelled 29.8 11 PDB header:lyase Chain: A: PDB Molecule:cg1753, isoform a; PDBTitle: full length structure of cystathionine beta-synthase from drosophila2 in complex with aminoacrylate 92 c2floA_ not modelled 29.7 14 PDB header:hydrolase Chain: A: PDB Molecule:exopolyphosphatase; PDBTitle: crystal structure of exopolyphosphatase (ppx) from e. coli o157:h7 93 c3qo6B_ not modelled 28.7 36 PDB header:photosynthesis Chain: B: PDB Molecule:protease do-like 1, chloroplastic; PDBTitle: crystal structure analysis of the plant protease deg1 94 c2z9iB_ not modelled 28.5 20 PDB header:hydrolase Chain: B: PDB Molecule:probable serine protease pepd; PDBTitle: crystal structure of rv0983 from mycobacterium tuberculosis-2 proteolytically active form 95 c2es4D_ not modelled 28.2 30 PDB header:hydrolase Chain: D: PDB Molecule:lipase chaperone; PDBTitle: crystal structure of the burkholderia glumae lipase-2 specific foldase in complex with its cognate lipase 96 d2es4d1 not modelled 28.2 30 Fold:Non-globular all-alpha subunits of globular proteins Superfamily:Lipase chaperone-like Family:Lipase chaperone LifO-like 97 c2hc8A_ not modelled 28.1 27 PDB header:transport protein Chain: A: PDB Molecule:cation-transporting atpase, p-type; PDBTitle: structure of the a. fulgidus copa a-domain 98 d2nn6i1 not modelled 27.8 33 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 99 c3shuB_ not modelled 27.0 19 PDB header:cell adhesion Chain: B: PDB Molecule:tight junction protein zo-1; PDBTitle: crystal structure of zo-1 pdz3 100 c2d90A_ not modelled 26.9 19 PDB header:protein binding Chain: A: PDB Molecule:pdz domain containing protein 1; PDBTitle: solution structure of the third pdz domain of pdz domain2 containing protein 1 101 c3epmB_ not modelled 26.8 20 PDB header:biosynthetic protein Chain: B: PDB Molecule:thiamine biosynthesis protein thic; PDBTitle: crystal structure of caulobacter crescentus thic 102 c2posD_ not modelled 26.2 27 PDB header:toxin Chain: D: PDB Molecule:sylvaticin; PDBTitle: crystal structure of sylvaticin, a new secreted protein2 from pythium sylvaticum 103 d2plta_ not modelled 25.9 33 Fold:Cupredoxin-like Superfamily:Cupredoxins Family:Plastocyanin/azurin-like 104 d1gmua1 not modelled 25.4 40 Fold:Urease metallochaperone UreE, N-terminal domain Superfamily:Urease metallochaperone UreE, N-terminal domain Family:Urease metallochaperone UreE, N-terminal domain 105 c3k50A_ not modelled 25.0 11 PDB header:hydrolase Chain: A: PDB Molecule:putative s41 protease; PDBTitle: crystal structure of putative s41 protease (yp_211611.1) from2 bacteroides fragilis nctc 9343 at 2.00 a resolution 106 d1fcja_ not modelled 24.7 15 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 107 c2a3nA_ not modelled 24.6 20 PDB header:sugar binding protein Chain: A: PDB Molecule:putative glucosamine-fructose-6-phosphate aminotransferase; PDBTitle: crystal structure of a putative glucosamine-fructose-6-phosphate2 aminotransferase (stm4540.s) from salmonella typhimurium lt2 at 1.353 a resolution 108 c1cg2D_ not modelled 24.5 14 PDB header:metallocarboxypeptidase Chain: D: PDB Molecule:carboxypeptidase g2; PDBTitle: carboxypeptidase g2 109 d1l1ca_ not modelled 24.4 29 Fold:GroES-like Superfamily:SacY-like RNA-binding domain Family:BglG-like antiterminator proteins 110 c3omlA_ not modelled 24.1 13 PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:peroxisomal multifunctional enzyme type 2, cg3415; PDBTitle: structure of full-length peroxisomal multifunctional enzyme type 22 from drosophila melanogaster 111 d2v4jc1 not modelled 23.9 36 Fold:DsrC, the gamma subunit of dissimilatory sulfite reductase Superfamily:DsrC, the gamma subunit of dissimilatory sulfite reductase Family:DsrC, the gamma subunit of dissimilatory sulfite reductase 112 c3ixzA_ not modelled 23.7 19 PDB header:hydrolase Chain: A: PDB Molecule:potassium-transporting atpase alpha; PDBTitle: pig gastric h+/k+-atpase complexed with aluminium fluoride 113 d1uepa_ not modelled 23.7 28 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 114 d2ba0a1 not modelled 23.5 24 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 115 c2q3gA_ not modelled 22.6 19 PDB header:structural genomics Chain: A: PDB Molecule:pdz and lim domain protein 7; PDBTitle: structure of the pdz domain of human pdlim7 bound to a c-2 terminal extension from human beta-tropomyosin 116 c3gpqA_ not modelled 22.3 9 PDB header:viral protein/rna Chain: A: PDB Molecule:non-structural protein 3; PDBTitle: crystal structure of macro domain of chikungunya virus in complex with2 rna 117 d2c4va1 not modelled 22.2 23 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 118 c2e6zA_ not modelled 22.1 31 PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt5; PDBTitle: solution structure of the second kow motif of human2 transcription elongation factor spt5 119 d1qvpa_ not modelled 22.0 33 Fold:SH3-like barrel Superfamily:C-terminal domain of transcriptional repressors Family:FeoA-like 120 c2cauA_ not modelled 21.8 21 PDB header:plant protein Chain: A: PDB Molecule:protein (canavalin); PDBTitle: canavalin from jack bean

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0