Phyre 2 alignment of P22188 with c3dg8B_

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Job Description | P22188
Confidence | 24.46% | Date | Thu Jan 5 11:38:45 GMT 2012
Rank | 411 | Aligned Residues | 68
% Identity | 18% | Template | c3dg8B_
PDB info | PDB header:oxidoreductase, transferase | Chain: B: PDB Molecule:bifunctional dihydrofolate reductase-thymidylate | PDBTitle: quadruple mutant (n51i+c59r+s108n+i164l) plasmodium2 falciparum dihydrofolate reductase-thymidylate synthase3 (pfdhfr-ts) complexed with rjf670, nadph, and dump
Resolution | 2.58 Å

| Insertion relative to template
| Deletion relative to template
| Catalytic residue from the CSA
Detailed help on interpreting your alignment

|  | 335 | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 |  | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . |  |  | . | . | . | . | 410 | .
Predicted Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |  |  |  |  |
Query SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |  |  |  |  |
Query Sequence |  | R | L | Q | P | V | C | G | R | M | E | V | F | T | A | P | G | . | K | P | T | V | V | V | D | Y | A | H | T | P | D | A | L | E | K | A | L | Q | A | A | R | L | H | C | A | G | K | L | W | C | V | F | G | C | G | G | D | R | D | K | G | K | R | P | L | M | G | A | I | A | E | E | F | . | . | A | D | V | A | V | V
Query Conservation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |  |  |  |  |
Alig confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | . | . |  |  |  |  |  |
Template Conservation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Sequence |  | K | F | K | P | L | S | N | R | I | N | V | I | L | S | R | T | L | K | K | E | D | F | D | E | D | V | Y | I | I | N | K | V | E | D | L | I | V | L | L | G | K | L | N | Y | Y | K | C | F | I | L | G | G | . | . | . | . | . | . | . | . | . | . | S | V | V | Y | Q | E | F | L | E | K | K | L | I | K | K | I | Y | F
Template Known Secondary structure |  | T | T |  | S |  | T | T |  |  |  |  |  |  |  | S | S |  |  | T | T | T | S |  | S | S | S |  |  |  | S | S | T | T |  |  |  |  |  |  |  | T | S |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  | T | T |  |  | S |  |  |  |
Template Predicted Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | 115 | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | .
|  | 412
Predicted Secondary structure |  |
Query SS confidence |  |
Query Sequence |  | T
Query Conservation |  |
Alig confidence |  |
Template Conservation |  |
Template Sequence |  | T
Template Known Secondary structure |  |
Template Predicted Secondary structure |  |
Template SS confidence |  |
|  | 185

Download: | Text version

No model constructed - rank, confidence too low

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys |
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