BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (555 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q47208 Protein fdrA n=96 Tax=Proteobacteria RepID=FDRA_...  1130   0.0  
UniRef50_D1AQ78 FdrA family protein n=1 Tax=Sebaldella termitidi...   496   e-139
UniRef50_C5BXU8 FdrA family protein n=1 Tax=Beutenbergia caverna...   478   e-133
UniRef50_C0WN22 Membrane protein n=1 Tax=Lactobacillus buchneri ...   388   e-106
UniRef50_UPI000182709D FdrA family protein n=1 Tax=Enterobacter ...   330   7e-89
UniRef50_B9KYM7 Protein fdrA n=1 Tax=Thermomicrobium roseum DSM ...   328   2e-88
UniRef50_Q2RGM5 FdrA n=1 Tax=Moorella thermoacetica ATCC 39073 R...   315   3e-84
UniRef50_Q0TAN3 YahF/FdrA-like protein n=18 Tax=Gammaproteobacte...   315   3e-84
UniRef50_C1D754 YahF/FdrA-like protein n=1 Tax=Laribacter hongko...   311   3e-83
UniRef50_Q7BSA0 YahF/FdrA-like protein n=3 Tax=Proteobacteria Re...   310   1e-82
UniRef50_B0VJR0 FdrA n=1 Tax=Candidatus Cloacamonas acidaminovor...   307   6e-82
UniRef50_A8VR79 Phage Terminase n=3 Tax=Firmicutes RepID=A8VR79_...   306   2e-81
UniRef50_C2GZK2 Bacterial FdrA protein n=28 Tax=Bacteria RepID=C...   302   2e-80
UniRef50_P77187 Uncharacterized protein yahF n=55 Tax=Proteobact...   301   4e-80
UniRef50_C0D6C1 Putative uncharacterized protein n=1 Tax=Clostri...   301   6e-80
UniRef50_A6TL44 FdrA family protein n=3 Tax=Clostridiales RepID=...   290   9e-77
UniRef50_D1B8P5 FdrA family protein n=1 Tax=Thermanaerovibrio ac...   287   8e-76
UniRef50_D0WIW7 Protein FdrA n=1 Tax=Slackia exigua ATCC 700122 ...   286   1e-75
UniRef50_D2L8W4 FdrA family protein n=1 Tax=Desulfovibrio sp. FW...   249   2e-64
UniRef50_A1SGR4 FdrA family protein n=1 Tax=Nocardioides sp. JS6...   248   6e-64
UniRef50_D1A7Z1 FdrA family protein n=2 Tax=Actinomycetales RepI...   240   8e-62
UniRef50_D2S3V1 FdrA family protein n=8 Tax=Bacteria RepID=D2S3V...   221   6e-56
UniRef50_C7QE97 FdrA family protein n=1 Tax=Catenulispora acidip...   167   1e-39
UniRef50_C0XJA3 Putative uncharacterized protein (Fragment) n=1 ...   101   9e-20
UniRef50_Q2TTV5 Putative uncharacterized protein n=1 Tax=Escheri...    80   2e-13
UniRef50_A3DLS0 Succinyl-CoA synthetase (ADP-forming) alpha subu...    65   6e-09
UniRef50_Q58643 Succinyl-CoA ligase [ADP-forming] subunit alpha ...    57   2e-06
UniRef50_C9KQT1 Succinyl-CoA ligase [ADP-forming] subunit alpha ...    50   2e-04
UniRef50_P53595 Malate--CoA ligase subunit alpha n=184 Tax=cellu...    50   2e-04
UniRef50_A6TL45 Putative uncharacterized protein n=3 Tax=Clostri...    49   4e-04
UniRef50_C0BZV5 Putative uncharacterized protein n=2 Tax=Clostri...    47   0.001
UniRef50_Q3ADM2 Succinyl-CoA ligase [ADP-forming] subunit alpha ...    47   0.002
UniRef50_B8FZH7 CoA-binding domain protein n=1 Tax=Desulfitobact...    44   0.011
UniRef50_A9A4P2 CoA-binding domain protein n=9 Tax=Archaea RepID...    44   0.013
UniRef50_D2L8W2 Putative uncharacterized protein n=1 Tax=Desulfo...    44   0.014
UniRef50_B5I859 Succinyl-CoA ligase [ADP-forming] subunit alpha ...    44   0.016
UniRef50_UPI00016B24F6 succinyl-CoA synthetase, alpha subunit n=...    42   0.052
UniRef50_Q65SV2 Succinyl-CoA ligase [ADP-forming] subunit alpha ...    41   0.099

>UniRef50_Q47208 Protein fdrA n=96 Tax=Proteobacteria RepID=FDRA_ECOLI
          Length = 555

 Score = 1130 bits (2924), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 555/555 (100%), Positives = 555/555 (100%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT
Sbjct: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL
Sbjct: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI
Sbjct: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
           AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA
Sbjct: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW
Sbjct: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300

Query: 301 FASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADD 360
           FASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADD
Sbjct: 301 FASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADD 360

Query: 361 THQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIG 420
           THQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIG
Sbjct: 361 THQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIG 420

Query: 421 FGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVS 480
           FGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVS
Sbjct: 421 FGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVS 480

Query: 481 SLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPV 540
           SLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPV
Sbjct: 481 SLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPV 540

Query: 541 AGGNKKLARLLERLQ 555
           AGGNKKLARLLERLQ
Sbjct: 541 AGGNKKLARLLERLQ 555


>UniRef50_D1AQ78 FdrA family protein n=1 Tax=Sebaldella termitidis ATCC 33386
           RepID=D1AQ78_SEBTE
          Length = 573

 Score =  496 bits (1277), Expect = e-139,   Method: Compositional matrix adjust.
 Identities = 252/582 (43%), Positives = 364/582 (62%), Gaps = 36/582 (6%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           M++  IKK  +QDSV+LM+++++LS +E ++ +SVMMGTPANK +   +G + ++  +AT
Sbjct: 1   MLYTIIKKNSYQDSVNLMLLTKELSAAEGIEKISVMMGTPANKEIFANSGLYTEELESAT 60

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           PNDIC+ I +E  D G    I++ +E  LK  +  S   + +   R WDSA +KLPDANL
Sbjct: 61  PNDICIVIDTE--DEGKIDGILESIESFLKNQSSKS-KGKKIPVARTWDSALRKLPDANL 117

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           A+IS+ GEYAAE  ++AL++ LNV +FSDNV++EDE ++K  AR KGLLVMGPDCGT +I
Sbjct: 118 AIISIPGEYAAEETSKALEKGLNVFLFSDNVSIEDEKRIKEEARTKGLLVMGPDCGTGII 177

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            G PLAFANV+ +GNIG++GASGTGIQE+ + I+  G GIT AIG GGRDLS ++  ++A
Sbjct: 178 GGLPLAFANVIEKGNIGIVGASGTGIQEISTIISRKGYGITQAIGTGGRDLSAQIEAVTA 237

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           + AL++L+ADE ++V+ F+SKPPA  VR K++   K  GKP VA FLG       D NV+
Sbjct: 238 IEALKLLAADEDTDVIVFISKPPAPEVRDKVIETFKILGKPVVANFLGDKKRENHD-NVF 296

Query: 301 FASSLDEAARLAC------------LLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAG 348
           +  +L++ A                +   +   ++ I       I GLY GGTLAAE   
Sbjct: 297 YTHTLEDTALKTVEIAEKYKISEKNIRKEIKEVKDIIENKEQRSIKGLYCGGTLAAETGM 356

Query: 349 LLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKP 408
           ++  + G+E   +H  GMML  + H+IIDLGDDFYT GRPHPMIDP++R  ++ ++  +P
Sbjct: 357 IIRDYYGIEDSGSHDKGMMLHYNGHEIIDLGDDFYTQGRPHPMIDPSIRVDMVYEMAKRP 416

Query: 409 QVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYA----IATVTGTERDPQCR 464
           +  V+LLD VIG+G   D A       ++     +   P Y     IA++TGTE DPQ  
Sbjct: 417 ETAVILLDNVIGYGGHEDMAGVFAPVIKE-----IKEDPAYKKIVFIASITGTENDPQKY 471

Query: 465 SQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAV----------- 513
           S+Q   LED+G  V  S  +AT +A  +I  L  +   +  +  E++ V           
Sbjct: 472 SEQYKKLEDSGAVVCESNAQATRMAVEIIKSLEKSETNNIETGEESIEVKSNIINTEPVI 531

Query: 514 INIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ 555
           INIGL  FA  ++     V+ Y W+P AGG+K+LA +L++L+
Sbjct: 532 INIGLGKFAETVKKYDAKVIQYNWAPTAGGDKRLAEILKKLR 573


>UniRef50_C5BXU8 FdrA family protein n=1 Tax=Beutenbergia cavernae DSM 12333
           RepID=C5BXU8_BEUC1
          Length = 562

 Score =  478 bits (1230), Expect = e-133,   Method: Compositional matrix adjust.
 Identities = 269/568 (47%), Positives = 360/568 (63%), Gaps = 21/568 (3%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           M+   IK   +QDSVSLM++S +LS  + V+ VS+MMGTPANK +   TGF  D+   A 
Sbjct: 1   MLQTIIKPNTYQDSVSLMMLSTQLSGLDAVERVSIMMGTPANKEIFRDTGFGSDELEGAG 60

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           P+D+ +A+  EA  AG A  I  ++ E LK  A  + S+    +VR  D A   LPDANL
Sbjct: 61  PSDLVIAL--EADGAGAADLISGRVAEFLKSQASAA-SATTYPRVRSLDRALTALPDANL 117

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           AL+S+ GE AA   ++ LD++L+V +FSDN+ ++DE++LK +ARE+GLL+MGPDCGT  +
Sbjct: 118 ALVSIPGEQAAPEIDRLLDKDLHVFVFSDNLAVDDEVRLKHKARERGLLMMGPDCGTGSL 177

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            G PLAF N++  G+IG++GASGTG QE+  QI  AG G++ AIGLGGRDLS +VG ++ 
Sbjct: 178 GGLPLAFTNIVTPGSIGIVGASGTGTQEVMVQIDRAGGGVSQAIGLGGRDLSEKVGAVTC 237

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           L AL  L AD  + V+  VSKPPA +VR  +++  +    P VA+ LG  PAV  D NV 
Sbjct: 238 LQALRALDADPGTSVITLVSKPPAPSVRETVLDVCQELATPVVAILLGEQPAVEVDGNVH 297

Query: 301 FASSLDEAARLACLLSRVTARRNA----IAPVSSGFICGLYTGGTLAAEAAGLLAGHLGV 356
           FA++LDEAARLA  L+       A    +AP     I GL+ GGTL +EAA LL+  LGV
Sbjct: 298 FAATLDEAARLAVSLAGTVTDEEAPAVELAP-GQRTITGLFCGGTLTSEAAILLSRGLGV 356

Query: 357 EADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLD 416
             D  H  G ML  D H +IDLGDD YT GRPHPMIDP+LR Q+I D     Q+ VLLLD
Sbjct: 357 PTDAEHADGYMLHHDGHTVIDLGDDAYTQGRPHPMIDPSLRAQMIRDAFDDRQLAVLLLD 416

Query: 417 VVIGFGATADPAASLVSAWQKAC-AARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAG 475
           VV GFG+  DPA ++V A +    AAR D + +  +A+V GTE+DPQ  S+Q  TL++AG
Sbjct: 417 VVTGFGSHEDPAGAIVGAIEAGREAARADGREVVVVASVCGTEKDPQPLSEQTRTLQEAG 476

Query: 476 IAVVSSLPEATLLAAALIHPLSPAAQQHTPSLL---------ENVAVINIGLRSFALELQ 526
           + V+ S   AT  A  ++   S   ++ TP+ +         E   V+N+GL SFA  LQ
Sbjct: 477 VVVLGSNAAATRYALGVV---SRTGERRTPAEIPEPTRRLVSEAPRVVNVGLASFADTLQ 533

Query: 527 SASKPVVHYQWSPVAGGNKKLARLLERL 554
                VV Y WSP+AGGN +L R+L  L
Sbjct: 534 ERGGQVVQYTWSPLAGGNARLQRILAAL 561


>UniRef50_C0WN22 Membrane protein n=1 Tax=Lactobacillus buchneri ATCC 11577
           RepID=C0WN22_LACBU
          Length = 587

 Score =  388 bits (996), Expect = e-106,   Method: Compositional matrix adjust.
 Identities = 227/589 (38%), Positives = 335/589 (56%), Gaps = 44/589 (7%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           M+H  I+K  +QDS+ LM+++  L   + V++V VMMGTPANK +  T G   D+ + A 
Sbjct: 1   MLHTIIEKNSYQDSIVLMLLTNYLETLDGVNNVQVMMGTPANKDIFKTGGLATDELDEAK 60

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALK-QLAQGSGSSQALTQVRRWDSACQKLPDAN 119
           P+D+ + I +E+ D  +   ++ + ++ L  Q   G+ +  A  +V+ WD A +   DA 
Sbjct: 61  PSDMVIVIDTESDD--LIDEVVDKAKDYLDAQGKAGNENETADERVKTWDKALELGKDAP 118

Query: 120 LALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSM 179
           +ALISV G YAA    +ALD   NV  FSDNV++EDE +LK  A EKGL++MGPDCGT +
Sbjct: 119 VALISVPGVYAAVEVEKALDAGKNVFCFSDNVSMEDEARLKQMAHEKGLVLMGPDCGTGI 178

Query: 180 IAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGIS 239
             G PLAFAN + +G+IG++GASGTGIQE+ + I   G G+T+AIG GGRDL  ++ G +
Sbjct: 179 ANGIPLAFANRVRKGSIGMVGASGTGIQEVSTIIHKLGAGVTNAIGTGGRDLKADIQGTT 238

Query: 240 ALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENV 299
              ++ +L  D   +V+  +SKPPA  VR  +++ ++AT KP VA+FLG  P  + +E +
Sbjct: 239 FKDSVALLDQDPDVKVIVAISKPPAPEVRDDVLSLLRATNKPVVAIFLGEKP-TSHEEGL 297

Query: 300 WFASSLDEAARLACLLSRVTARRNAIAPVS---------------SGFICGLYTGGTLAA 344
           + A +L+E AR+A  L       N   P S                 +I G Y+GGTLA 
Sbjct: 298 YRAYTLEETARIAVDL------LNGKTPGSYDDELKIPDIQLEPQQKYIKGYYSGGTLAY 351

Query: 345 EAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADL 404
           EAA L+   L + A+D    G +L  + +++IDLGDD YT GRPHPMID T R +++ + 
Sbjct: 352 EAATLMNDALNLNAEDAGD-GFILQKEGYEVIDLGDDVYTQGRPHPMIDATKRKEMMVEA 410

Query: 405 GAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACA-ARLDNQPLYAIATVTGTERDPQC 463
           G  PQ   +L+D+V+G+GA  + A  L  A +K  A A+   + L  I T+ GT+ DPQ 
Sbjct: 411 GNDPQTAAILIDIVLGYGAHDNMAGELAPAIKKVIADAKNQGRNLPVIGTIVGTDLDPQN 470

Query: 464 RSQQIATLEDAGIAVVSSLPEATLLAAALI--------HPLSPA---------AQQHTPS 506
            ++Q   LE AG+ +  S  +A   A AL+         P+ P            +    
Sbjct: 471 YAEQKDILEAAGVILCQSNAQAVKTALALVGKPIFGEPKPIRPKKSSTAVMPEVSEDLRQ 530

Query: 507 LLENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ 555
           +L     IN+GL SF+  +       V ++W PVAGGN  L + L  L 
Sbjct: 531 MLTATKFINVGLDSFSEAINENGGDAVQFEWHPVAGGNVTLQKALNYLN 579


>UniRef50_UPI000182709D FdrA family protein n=1 Tax=Enterobacter cancerogenus ATCC 35316
           RepID=UPI000182709D
          Length = 513

 Score =  330 bits (847), Expect = 7e-89,   Method: Compositional matrix adjust.
 Identities = 204/510 (40%), Positives = 288/510 (56%), Gaps = 31/510 (6%)

Query: 6   IKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDIC 65
           IKK  + DSVSLM +S K ++   V+   V M T  NK +L   G    +   A   D+ 
Sbjct: 7   IKKNTWFDSVSLMSVSTKANKLPGVEQAVVAMATEMNKGVLHNLGLLTPELAEAKNGDLM 66

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISV 125
           + I+ EAA+     AI     EAL    + +GS +A  +     SA    PDANLA+ISV
Sbjct: 67  IVIKGEAANDETLAAI-----EALFTRKESAGSHEA--RYATIASAKAHRPDANLAVISV 119

Query: 126 AGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPL 185
            G +AA  A QAL+ +LNVM+FSDNV+L+DE+ LK  A +KGLL+MGPDCGT++I G  L
Sbjct: 120 NGTFAAREARQALENDLNVMLFSDNVSLDDELALKQLAHQKGLLMMGPDCGTAIINGAGL 179

Query: 186 AFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALE 245
            FAN +  G+IG++GASGTG QEL  +I   G G++  IG GGRDLS ++GG+  L A+ 
Sbjct: 180 CFANAVCRGSIGIVGASGTGSQELSVRIHEFGGGVSQLIGTGGRDLSEKIGGLMMLDAIA 239

Query: 246 MLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSL 305
           ML ADE ++ +  +SKPPA AV  K++   +A  KP +A FLG     A ++ + FA   
Sbjct: 240 MLEADENTQAIVLISKPPAPAVAEKVLARARACRKPVIACFLGRNAPPADEDGLQFARGT 299

Query: 306 DEAARLACLLSRVTARRNAIAPVS--------------SGFICGLYTGGTLAAEAAGLLA 351
            EAA  A LL+ +      + P++                +I GL+ GGTL  EA  + A
Sbjct: 300 KEAALKAVLLTGIKQESLDLHPLNWPLIEEVRARQTPQQKYIRGLFCGGTLCDEA--MFA 357

Query: 352 G-------HLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADL 404
                   +  ++ D   +   +  + +H  +D GDD +T GRPHPMIDP+ R   +   
Sbjct: 358 ALEKYDDVYSNIQPDPAKRLSDINVSQAHTFLDFGDDDFTHGRPHPMIDPSNRITRLLQE 417

Query: 405 GAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACA-ARLDNQPLYAIATVTGTERDPQC 463
              P+V V+++D V+GFGA  DP   ++ A Q+A A A+ DN+PL  +  V GT++DPQ 
Sbjct: 418 ARDPEVAVIVMDFVLGFGAHDDPVGVMIDAIQEAQAIAKADNRPLVILGYVLGTDQDPQS 477

Query: 464 RSQQIATLEDAGIAVVSSLPEATLLAAALI 493
            +QQ   L DAG+   SS     LLA   +
Sbjct: 478 LAQQCERLTDAGVIWASSSTNTGLLAREFV 507


>UniRef50_B9KYM7 Protein fdrA n=1 Tax=Thermomicrobium roseum DSM 5159
           RepID=B9KYM7_THERP
          Length = 514

 Score =  328 bits (842), Expect = 2e-88,   Method: Compositional matrix adjust.
 Identities = 201/505 (39%), Positives = 292/505 (57%), Gaps = 29/505 (5%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           ++   I+   + DSV+LM ++  ++    VD  +++MGT AN  LL  +G W +     +
Sbjct: 2   VVRIRIEPNSYFDSVALMAVASVVNRLPGVDLAALLMGTSANLELLRDSGLWDERLETVS 61

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           PND+ +A+R  A+D   A+  + +    L+  A+ S  S+A   +R   +A +++  A++
Sbjct: 62  PNDLVIAVR--ASDDAAAERAIDEAVHRLRSSARTSQVSEAKVTLRTLRTALRQVSQASV 119

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
             ISV G YA   A +AL  + +V +FSDNV +E+E++LK  A+E+GLL+MGPDCGT+ I
Sbjct: 120 VAISVPGPYAPIEAEEALRADRHVFLFSDNVPIEEEVRLKELAQERGLLLMGPDCGTAFI 179

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
           AG  L F N +  G IG++ A+GTG+Q+L S I   G GI+H IG GGRDL   VGG + 
Sbjct: 180 AGLGLGFMNAVRRGPIGIVAAAGTGLQQLASLIDWFGSGISHGIGTGGRDLDARVGGRTM 239

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           L  LE L+ D  ++V+  VSKPPA  V  K++    A GKP VA F+G T  V   E V 
Sbjct: 240 LAGLEALAHDPATQVIVLVSKPPAPEVAEKVLAFAAACGKPVVATFIGQTAPVT--EGVH 297

Query: 301 FASSLDEAARLAC------------------LLSRVTARRNAIAPVSSGFICGLYTGGTL 342
            A++L EAARLA                    L+RV A R+ +AP    ++ GLY+GGTL
Sbjct: 298 VAANLTEAARLAVHLATGQSLADLDLPRRQEALARVRAERSRLAPTQR-YLRGLYSGGTL 356

Query: 343 AAEAAGLLAGHLG-VEADDTHQHGMMLD----ADSHQIIDLGDDFYTVGRPHPMIDPTLR 397
             EA  LL   +G + ++   Q  + L     ++ H  +DLG D +TVGRPHPMID T+R
Sbjct: 357 CDEAMVLLQPRIGPIRSNIPLQPELRLTDPHRSEEHTFVDLGSDEFTVGRPHPMIDQTIR 416

Query: 398 NQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKA-CAARLDNQPLYAIATVTG 456
            +      A P V  ++LD+V+G+GA +DPAA L  A ++A   A    + L  I  + G
Sbjct: 417 LERFRREAADPTVAGIVLDLVLGYGAASDPAAELAPAIREARVEAERTGRILPCIVALVG 476

Query: 457 TERDPQCRSQQIATLEDAGIAVVSS 481
           T+ DPQ  ++Q  TLEDAG  VV S
Sbjct: 477 TQSDPQDYARQRRTLEDAGAIVVPS 501


>UniRef50_Q2RGM5 FdrA n=1 Tax=Moorella thermoacetica ATCC 39073 RepID=Q2RGM5_MOOTA
          Length = 520

 Score =  315 bits (807), Expect = 3e-84,   Method: Compositional matrix adjust.
 Identities = 210/519 (40%), Positives = 290/519 (55%), Gaps = 32/519 (6%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           +I   IK   +QDSV LM +S +L + + V   SV+M T  NK+ L   G    +   A 
Sbjct: 2   VIRWLIKPKMYQDSVKLMKLSAELRKQDGVKQASVIMATEMNKSTLQDIGMLVPEVAAAN 61

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALK--QLAQGSGSSQALTQVRRWDSACQKLPDA 118
            +D+ + + ++  +   AQ  ++  E+ L   ++ QG    Q    +R   SA + LP A
Sbjct: 62  ADDLAIIVAADTEEQ--AQKAVELAEKLLNRAEVQQGETKQQFPKTLR---SAVEALPGA 116

Query: 119 NLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTS 178
           NLALISV G YAA  A +AL+  LNV +FSDNVTLEDE++LK    +KGLLVMGPDCGT+
Sbjct: 117 NLALISVPGTYAAAEALKALNLGLNVHLFSDNVTLEDEVRLKQIGTKKGLLVMGPDCGTA 176

Query: 179 MIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGI 238
           +I G PLAFANV+  G IG++GASGTGIQE    I   G GI+HAIG GGRDL  EVGG 
Sbjct: 177 IIDGVPLAFANVVARGKIGIVGASGTGIQEATVLIERLGGGISHAIGTGGRDLLDEVGGQ 236

Query: 239 SALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDEN 298
             L  +++L  D  +EV+  +SKP       KI++ +K   KP V   L       +   
Sbjct: 237 MMLLGIDLLEDDPATEVILLISKPAGPRTANKILDRVKQCKKPVVVNLLKGDLNAIQSAG 296

Query: 299 VWFASSLDEAARLACLLS------------------RVTARRNAIAPVSSGFICGLYTGG 340
           V  A+++++AA  A  L+                  ++    + + P +  +I GL+TGG
Sbjct: 297 VVGAATIEDAAYKAVALANGEEAVAMPENYWGDYSKQIAMLESQLGP-NQRYIRGLFTGG 355

Query: 341 TLAAEAAGLLAGHLG-VEADDTHQHGMML----DADSHQIIDLGDDFYTVGRPHPMIDPT 395
           TLA EA  +L+  +G + ++   +  + L     +  H I+DLGDD +T GRPHPMIDP 
Sbjct: 356 TLADEAMVILSDIVGDIFSNIPLKPELKLPSARKSHKHTIVDLGDDEFTRGRPHPMIDPL 415

Query: 396 LRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVT 455
            RN+ +    A P+V V+L DVV G+G+ ADPA  L  A  +A  A   N P   IA V 
Sbjct: 416 PRNERLMQEYADPEVGVILCDVVTGYGSHADPAGELARAVARARDAYPSNNP-AVIAFVC 474

Query: 456 GTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH 494
           GTE DPQ  S+Q+  LE  GI V+ S  EA   A  +I 
Sbjct: 475 GTEADPQPLSEQVKVLEKEGIFVLPSNAEAARAAGRIIK 513


>UniRef50_Q0TAN3 YahF/FdrA-like protein n=18 Tax=Gammaproteobacteria
           RepID=Q0TAN3_ECOL5
          Length = 519

 Score =  315 bits (807), Expect = 3e-84,   Method: Compositional matrix adjust.
 Identities = 206/507 (40%), Positives = 291/507 (57%), Gaps = 36/507 (7%)

Query: 11  FQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRS 70
           +QDSVSLM IS ++S+   +   SV+MGTP N   L   G  ++   NA+PND+ +A+  
Sbjct: 12  YQDSVSLMQISAQISKLPGIQQASVVMGTPNNLEQLRDAGLGNEI--NASPNDLVIAVMG 69

Query: 71  EAADAGIAQAIMQQ--LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGE 128
           E      A  + QQ    +   +   G  S + ++     + A +  P+ANLALISV G+
Sbjct: 70  EEDICNEALVLAQQRLTSKPDDETDSGIKSPEKVS----LEMALEAEPEANLALISVPGD 125

Query: 129 YAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFA 188
           YAA  A +AL+  +NVMMFSDNV++  E  +KT ARE+  +VMGPDCGT+++ G PL FA
Sbjct: 126 YAAAEAMKALNLGMNVMMFSDNVSIGQEKSIKTLARERQRIVMGPDCGTAIVNGIPLGFA 185

Query: 189 NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLS 248
           NV+  G IGVIGASGTG+QE+  +I   G GI+ A+G GG DLS E+GGIS L AL+ L+
Sbjct: 186 NVVKRGAIGVIGASGTGLQEVTCRIDQLGAGISQALGTGGHDLSEEIGGISMLFALDALA 245

Query: 249 ADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEA 308
            D+++ V+  +SKPP+  V   I+   +A GKP V  FLG  P      N+  A++L  A
Sbjct: 246 QDDETRVIVLISKPPSPIVAQTILERAEACGKPVVVNFLGANPHDLARPNITAATTLASA 305

Query: 309 ARLACLL---------------SRVTARRNAIA--PVSSGFICGLYTGGTLAAEAAGLLA 351
           A +A  L                 +T  +NA    P     I G++ GGT   EA  L+ 
Sbjct: 306 ANIAVALLNDQPIPAVETEISCDDLTMLQNACQRLPAHRQAIRGVFAGGTFCYEAQ-LIC 364

Query: 352 GHLGVE-ADDTHQHG-----MMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLG 405
              G   A +T   G      +  ++ H +ID+GDD +T G+PHPMIDPTLRNQ + +  
Sbjct: 365 QQKGFSAASNTPVAGNRALANIWQSEDHTLIDMGDDDFTRGKPHPMIDPTLRNQRLLNEL 424

Query: 406 AKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRS 465
                 V+L D+V+G+GA+  PA+ L+          ++N PL  IA V GTE DPQ RS
Sbjct: 425 NDSHTAVVLFDLVLGYGASTTPASELLDQLSH---IDMNNAPLL-IAHVCGTEADPQIRS 480

Query: 466 QQIATLEDAGIAVVSSLPEATLLAAAL 492
           QQI  L++AG+ + SS  +A L A+ +
Sbjct: 481 QQIRALQNAGVIIASSNAQAALWASTV 507


>UniRef50_C1D754 YahF/FdrA-like protein n=1 Tax=Laribacter hongkongensis HLHK9
           RepID=C1D754_LARHH
          Length = 512

 Score =  311 bits (798), Expect = 3e-83,   Method: Compositional matrix adjust.
 Identities = 211/518 (40%), Positives = 288/518 (55%), Gaps = 35/518 (6%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           +H  I +  ++DSV+LM +S  L+  + +   S +M TPAN ALL   G   D    A P
Sbjct: 3   LHLAILRNQYRDSVALMQLSAALARLDGITQASAVMATPANLALLSRAGLL-DTPPEAAP 61

Query: 62  NDICVAIRSEAA--DAGIAQAIMQQLEEALKQLAQGSGS--SQALTQVRRWDSACQKLPD 117
           ND+ +A+  E A  DA +  A  Q LE    Q A G     + +LT       A  + PD
Sbjct: 62  NDLLIALEGEEAAFDAALTHA-RQALEAKGGQSAGGPAELPANSLTM------ALSRQPD 114

Query: 118 ANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           +NLALISV G YA   A +AL   LNVM+FSDNV+ EDE +LK  A   G +VMGPDCGT
Sbjct: 115 SNLALISVPGAYATAEAEKALRAGLNVMLFSDNVSGEDERRLKQLATGLGRIVMGPDCGT 174

Query: 178 SMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGG 237
           ++I G PLAFANV   G IG +GASGTG+Q++ + I   GEGI+ AIG GG DL+  VGG
Sbjct: 175 AIIHGVPLAFANVCRAGAIGCVGASGTGLQQITTLIDTLGEGISQAIGTGGHDLAESVGG 234

Query: 238 ISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA-VARD 296
           +S L  +  L+ D+ + V+  VSKPPAEAV  K+++A  A GKP V  FLG  PA + + 
Sbjct: 235 LSMLAGIRALAEDDATRVIVLVSKPPAEAVARKVLDAAIAAGKPVVVNFLGADPARLPQH 294

Query: 297 ENVWFASSLDEAARLACLLSR---------------VTARRNAIAPVSSGFICGLYTGGT 341
            N+ +A++L+ AAR+A    R                 A +  + P  +  + GLY+GGT
Sbjct: 295 ANLHYATTLESAARMAVACVRGEPLQDTPPQPHPETAAALKARLQPQQT-RLRGLYSGGT 353

Query: 342 LAAEAAGLLAGHL-GVEADDTHQHGMMLD----ADSHQIIDLGDDFYTVGRPHPMIDPTL 396
              EA  +LA  L G+ ++         D    +  H +IDLGDD +T GRPHPMID  L
Sbjct: 354 FCYEATLMLADALPGLRSNTPTARAPAPDDVWHSAGHCLIDLGDDEFTRGRPHPMIDHRL 413

Query: 397 RNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLD-NQPLYAIATVT 455
           RN+      A   V V+L D+V+GFGA  DP A++     +      D  + +  +ATV 
Sbjct: 414 RNERFLAEAADETVAVILFDIVLGFGAHDDPLAAMHDTLTEVRRLTADAGREVALVATVC 473

Query: 456 GTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
           GT  DPQ   +Q A     G+ + +S  EA  LA A++
Sbjct: 474 GTAGDPQGFERQRAGFAALGVCLAASNAEAVALARAIV 511


>UniRef50_Q7BSA0 YahF/FdrA-like protein n=3 Tax=Proteobacteria RepID=Q7BSA0_ACIAI
          Length = 514

 Score =  310 bits (793), Expect = 1e-82,   Method: Compositional matrix adjust.
 Identities = 201/502 (40%), Positives = 282/502 (56%), Gaps = 18/502 (3%)

Query: 6   IKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDIC 65
           +++  +QDSV+LM +S  L   + V + S+MMGT  N  ++   G      N+A P D+ 
Sbjct: 7   VRRNTYQDSVTLMRLSSDLLAEDGVTNASIMMGTAGNIEIMREGGLDAPALNDARPTDLV 66

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDA-NLALIS 124
           +AI + + DA  A+  +++   AL   A  + S     Q R   S    + +  NL LIS
Sbjct: 67  IAIVAASEDA--ARTAIEKAIAALNTDAS-TASDGGGAQKRAISSVMGAVVEGVNLTLIS 123

Query: 125 VAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTP 184
           V GEYAA  A +AL   ++V +FSDNV++E EI LK  A  KGLL+MGPDCGT++I G P
Sbjct: 124 VPGEYAAAEAMKALKAGMHVHLFSDNVSVEKEIALKDVAISKGLLMMGPDCGTAIINGVP 183

Query: 185 LAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTAL 244
           + FAN +  G IGVI ASGTG QE+ S I   G GI+ A G GGRDLS  V G  A  AL
Sbjct: 184 VGFANAVRRGRIGVIAASGTGAQEVTSLIHELGSGISQAFGTGGRDLSSAVKGRMARFAL 243

Query: 245 EMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASS 304
           + L  D+ ++V+  +SKPPA  V   I++  K T KP V  FLG    + RD  +  A +
Sbjct: 244 KALLDDDMTDVIVLISKPPAPEVAASILDTAKGTSKPIVVCFLGGDSKMVRDHGLIPAET 303

Query: 305 LDEAARLACL--LSRVTARRNAIAPV------SSGFICGLYTGGTLAAEAAGLLAGHLG- 355
           L++AAR A        T  R A AP          ++ GL++GGT   EA  LL   +G 
Sbjct: 304 LEDAARQAVRAETGSDTGSRYAPAPTLPKLSKEQKYVRGLFSGGTFCYEALLLLREFVGD 363

Query: 356 VEADDTHQHGMMLDADS----HQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVR 411
           V ++      M L  ++    H  ID G+D +TVGRPHPM+D   RN  I      P+  
Sbjct: 364 VSSNTPINKQMKLKNNNISTGHVCIDFGEDEFTVGRPHPMLDFRFRNDRIVQEARDPETA 423

Query: 412 VLLLDVVIGFGATADPAASLVSAWQKAC-AARLDNQPLYAIATVTGTERDPQCRSQQIAT 470
           V+LLD+V+G+GA A+PA +L+ A +KA   AR + + L  +A+V GT  D Q   QQ A 
Sbjct: 424 VILLDLVLGYGANANPAGALMPAIRKAMEVARAEGRTLPIVASVCGTSDDLQGLEQQEAA 483

Query: 471 LEDAGIAVVSSLPEATLLAAAL 492
           L +AG+ ++SS  +A+  A  +
Sbjct: 484 LREAGVTILSSNAQASRFAGKI 505


>UniRef50_B0VJR0 FdrA n=1 Tax=Candidatus Cloacamonas acidaminovorans
           RepID=B0VJR0_9BACT
          Length = 505

 Score =  307 bits (787), Expect = 6e-82,   Method: Compositional matrix adjust.
 Identities = 195/492 (39%), Positives = 284/492 (57%), Gaps = 21/492 (4%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           I A I  G + DSV LM+ISR+L   + V +   ++ T  N+ +L  +    ++ N+A+ 
Sbjct: 3   IKAKIIAGKYLDSVKLMLISRELRSLKGVLEAVAIVATSENREILKASDMLAEEINSASE 62

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
           NDI + I+++ A    A+AI  + EE + + +    +   + Q    + A   L  A+L 
Sbjct: 63  NDIVIVIKADNAKNA-AEAI-NKAEELINKPSTNEYNQTPIPQAFTLEKAIATLGGADLC 120

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           LIS+AG+YAA  A +AL++ L++++FSDNV++EDE+ LK +A +KGLL+MGPDCGT+++ 
Sbjct: 121 LISIAGKYAAAEAEKALEKGLHILLFSDNVSIEDELSLKQKALKKGLLMMGPDCGTAILN 180

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G PLAFAN +P G IG++ ASGTG+QE+ + IA    GI+ A G GGRD  +E+GG+   
Sbjct: 181 GVPLAFANNVPRGKIGIVSASGTGLQEISTTIANLSGGISQAFGTGGRDGKKEIGGLMLT 240

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
             LE L  DE +EV+    KPP E V+ K+   +  + KP +A FL     V    N+++
Sbjct: 241 ACLEYLLEDENTEVIIVTGKPPCEEVQKKLWELISHSSKPVIANFL-IPMQVPELPNLYY 299

Query: 302 ASSLDEAARLACLLSRVTARRNAIA-----PVSSG-FICGLYTGGTLAAEAAGLLAGHLG 355
             SL E A  AC  + +  +   +A     P   G ++ GLY+GGTL  EA  +   + G
Sbjct: 300 VRSLSETAFFACKKAGIEVKNAKLAEDFPLPKLRGPYLRGLYSGGTLCQEAIQVYLDNFG 359

Query: 356 VEADD--THQHGMML----DADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQ 409
            E  +  T Q    L        + IIDLG D +T+GRPHPMID +LR Q +A     P+
Sbjct: 360 CEPFNNVTDQAFFRLTDGWQTKENSIIDLGADEFTIGRPHPMIDYSLRLQKLAQEANDPK 419

Query: 410 VRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIA 469
           V ++LLDVV+GFGA  DPA  LV A QK  A       L  +  + GT+ DPQ R +Q  
Sbjct: 420 VGIILLDVVLGFGAHPDPAEELVPALQKLPAD------LVVVCHLLGTDGDPQNRQKQKK 473

Query: 470 TLEDAGIAVVSS 481
            LE AG  V +S
Sbjct: 474 ELEKAGAYVFTS 485


>UniRef50_A8VR79 Phage Terminase n=3 Tax=Firmicutes RepID=A8VR79_9BACI
          Length = 519

 Score =  306 bits (783), Expect = 2e-81,   Method: Compositional matrix adjust.
 Identities = 197/520 (37%), Positives = 288/520 (55%), Gaps = 42/520 (8%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
              I+K  + DSV+LM ++ K+ + + V D  V M T  NK L    G   D+   A  N
Sbjct: 4   QVIIRKNAYYDSVTLMSLASKIEQLDGVHDAIVAMATAMNKELAGDIGLVTDEVEAAGDN 63

Query: 63  DICVAIRSEAADAGIAQAIMQQLEEALKQL--AQGSGSSQALTQVRR-WDSACQKLPD-- 117
           D+ +A+ +E   A         LEEA   +  A  + SSQA  Q  + + +  + L D  
Sbjct: 64  DLLLAVSAENEKA---------LEEAFTAIEAAFEAKSSQANKQTEKTYTNTKEALRDHE 114

Query: 118 -ANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCG 176
            ANLA+ISV+GE+AA  A  AL + L+VM+FSDNV++EDE +LK   R KGL VMGPDCG
Sbjct: 115 EANLAIISVSGEFAAREAEIALKKGLHVMIFSDNVSVEDERRLKELGRNKGLFVMGPDCG 174

Query: 177 TSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVG 236
           T+++ GT L FAN +  GNIG++ ASGTG+QE+  QI   G G++  IG GGRDLS+++G
Sbjct: 175 TAILNGTGLCFANSVRRGNIGLVAASGTGLQEVTVQIDRLGGGVSQGIGTGGRDLSKDIG 234

Query: 237 GISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARD 296
           G+  L  ++ L  D  ++V+  +SKPPA+ V+  ++  +KA+ KP V  F+   PA A  
Sbjct: 235 GLMMLQGIKALEEDPDTDVIVLISKPPAKEVQDLVLEQVKASRKPVVISFIDGDPAAAVS 294

Query: 297 ENVWFASSLDEAARLACLLSRVTA---------RRNAIAPVSSGF----------ICGLY 337
               F  SL + A  A  LS+             + A   V +G           I GLY
Sbjct: 295 AGAIFGYSLTDTAIKAVALSKGEEAPDKPADQFDKEAWETVLNGVREKRSDSQIDIRGLY 354

Query: 338 TGGTLAAEAAGLLAGH-LGVEADDTHQHGMML----DADSHQIIDLGDDFYTVGRPHPMI 392
            GGTL AEA  ++    L V+++   +    L    +++ H ++DLG+D +TVG+PHPMI
Sbjct: 355 GGGTLCAEALSIMRQEGLSVKSNVAKREEEKLFNTRESEGHVLLDLGEDEFTVGKPHPMI 414

Query: 393 DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIA 452
           DPT RNQ +    A  +  V+L+D  +G+G+  DP    +   ++   AR++N  L  ++
Sbjct: 415 DPTTRNQRLLQEAADEKTAVILMDFELGYGSHEDPVGVSLPFIEE---ARVNNPSLAIVS 471

Query: 453 TVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAAL 492
            V GT  DPQ      + L +AG+AV +S  EA  LA  L
Sbjct: 472 YVCGTATDPQGLESAESRLREAGVAVANSNVEAVRLAVHL 511


>UniRef50_C2GZK2 Bacterial FdrA protein n=28 Tax=Bacteria RepID=C2GZK2_ENTFA
          Length = 519

 Score =  302 bits (774), Expect = 2e-80,   Method: Compositional matrix adjust.
 Identities = 195/514 (37%), Positives = 280/514 (54%), Gaps = 39/514 (7%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           I   IK+  + DSV+LM IS + +E   V    + MGT  N  ++   G +    ++ T 
Sbjct: 3   IQTVIKENAYFDSVTLMTISTRANELAGVKTAMIGMGTDMNLEVIRNVGLYTPALDHVTT 62

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
               + I  +  D   ++ I+QQ++E   +  + + S       +  DSA  + PDANL 
Sbjct: 63  G--DLLIVLDLDDQANSEEILQQVDELFTKKKKTASSE---VTYKTLDSALHEEPDANLV 117

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           +ISV G++AA  A++ALD+  +VM+FSDNVT+++E+ LK +A EK L VMGPDCGT++I 
Sbjct: 118 VISVNGKFAAREAHKALDQQKHVMLFSDNVTVDEELALKQKAHEKELFVMGPDCGTAIIN 177

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G  L FAN +  G+IG++GASGTG QE+  QI   G GI+  IG GGRDLS E+GG+  L
Sbjct: 178 GVGLCFANEVRSGDIGIVGASGTGSQEVSVQIHKYGYGISQLIGTGGRDLSAEIGGLMML 237

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
             L+ L  DE+++ +  +SKPPA  V  KI+  +  + KP V  F+G      + +NV F
Sbjct: 238 DGLDALMVDEQTKAILLISKPPAPEVTEKILKKLAVSTKPVVIYFIGSEQTERKIDNVTF 297

Query: 302 ASSLDEAARLACLLSR----------------VTARRNAIAPVSSGFICGLYTGGTLAAE 345
           A+S  +A +     S+                +TA +   AP S  F+ GL+ GGTL  E
Sbjct: 298 ATSSLDAVQKVIQFSQTQEAETSLYQNPTGATLTAIQQQQAP-SQKFVRGLFCGGTLCDE 356

Query: 346 AAGLLAGHLGVEADDTHQHGMML---------DADSHQIIDLGDDFYTVGRPHPMIDPTL 396
               L   L   +DD + +   +          + +H +ID GDD +T GRPHPMIDPT 
Sbjct: 357 ----LLYALTEVSDDVYSNIHKIPERQLANPDHSQAHTLIDFGDDRFTEGRPHPMIDPTS 412

Query: 397 RNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACA-ARLDNQPLYAIATVT 455
           R   I      P+V VL LD  +G+G+  +P   L  A ++A A A+ D + L  I  V 
Sbjct: 413 RITRILQEAKDPEVAVLALDFELGYGSHENPVGVLAEALKEAKAIAKADGRELAIIGYVL 472

Query: 456 GTERDPQCRSQQIATLEDAGIAVVSS---LPEAT 486
           GTE DPQ   +Q   LED  + VV S   L EAT
Sbjct: 473 GTEEDPQDIHEQRKILEDLEVLVVDSSHQLCEAT 506


>UniRef50_P77187 Uncharacterized protein yahF n=55 Tax=Proteobacteria
           RepID=YAHF_ECOLI
          Length = 515

 Score =  301 bits (771), Expect = 4e-80,   Method: Compositional matrix adjust.
 Identities = 195/513 (38%), Positives = 281/513 (54%), Gaps = 27/513 (5%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           +   IK   + DSVSLM IS + ++ + V+   V M T  NK +L   G    +   A  
Sbjct: 3   VKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNKGVLKNLGLLTPELEQAKN 62

Query: 62  NDICVAIRSEA-ADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
            D+ + I  ++ AD    + ++ ++EE     AQ SGS +A  +     SA + +P++NL
Sbjct: 63  GDLMIVINGKSGADN---EQLLVEIEELFNTKAQ-SGSHEA--RYATIGSAKKHIPESNL 116

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           A+ISV G +AA  A QAL  +LNVM+FSDNV++EDE+ LK  A EKGLL+MGPDCGT++I
Sbjct: 117 AVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAHEKGLLMMGPDCGTAII 176

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            G  L F N +  GNIG++GASGTG QEL  +I   G G++  IG GGRDLS ++GG+  
Sbjct: 177 NGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQLIGTGGRDLSEKIGGLMM 236

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           L A+ ML  D ++E++A +SKPPA AV  K++   +A  KP V  FL        ++ + 
Sbjct: 237 LDAIGMLENDPQTEIIALISKPPAPAVARKVLERARACRKPVVVCFLDRGETPVDEQGLQ 296

Query: 301 FASSLDEAARLACLLSRV--------TARRNAIAPVSS------GFICGLYTGGTLAAEA 346
           FA    EAA  A +LS V        T  +  IA V +       +I GL+ GGTL  E 
Sbjct: 297 FARGTKEAALKAVMLSGVKQENLDLHTLNQPLIADVRARLQPQQKYIRGLFCGGTLCDET 356

Query: 347 AGLLAGHLG-----VEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLI 401
              +    G     ++ D   +   +  +  H  +D GDD +T G+PHPMIDPT R   +
Sbjct: 357 MFAVMEKHGDVYSNIQPDPEFRLKDINRSIKHTFLDFGDDDFTNGKPHPMIDPTNRISRL 416

Query: 402 ADLGAKPQVRVLLLDVVIGFGATADPAASLV-SAWQKACAARLDNQPLYAIATVTGTERD 460
            +    P+V V+++D V+GFG+  DP  S + +  +    A  + + L  +A V GT+ D
Sbjct: 417 IEEARDPEVAVIVMDFVLGFGSHEDPVGSTIETIKEAKAIAAAEGRELIILAYVLGTDLD 476

Query: 461 PQCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
                QQ   L DAG+ + SS     LLA   I
Sbjct: 477 TPSLEQQSQMLLDAGVILASSSTNTGLLAREFI 509


>UniRef50_C0D6C1 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0D6C1_9CLOT
          Length = 517

 Score =  301 bits (770), Expect = 6e-80,   Method: Compositional matrix adjust.
 Identities = 177/505 (35%), Positives = 279/505 (55%), Gaps = 23/505 (4%)

Query: 11  FQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRS 70
           ++DSV LM ++  + + E V++  V++ T ANK +L+  G   ++   ATPND+ V++  
Sbjct: 12  YRDSVLLMKMAGMVRKIEGVENAEVIIATEANKGILEFNGLLTEEIRKATPNDLVVSVI- 70

Query: 71  EAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYA 130
            A D  + +  +  +E+ +    +     +     +    A    P+A+LA++S+ G   
Sbjct: 71  -AGDETVIEKAIAAVEDMIFNGLEDDKGGKVTYSAKSIAGALAMEPEADLAILSIPGPLV 129

Query: 131 AELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANV 190
            + A + LD  +N+++FSDNV +EDE++LK +A E GL+VMGPDCGT+++ G  LAFAN 
Sbjct: 130 KKDAMKLLDSGVNLLIFSDNVPIEDELELKRKADEMGLMVMGPDCGTAIVRGASLAFANK 189

Query: 191 MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSAD 250
           + +G IG++ ASGTG+QE+   I   G+GI+HA+G G  D+   +GGIS    L+ L  D
Sbjct: 190 VRQGKIGMVCASGTGLQEVAVLIHNLGQGISHALGTGSNDVKDAIGGISMKRGLKWLEQD 249

Query: 251 EKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAAR 310
             +E++  VSKPP +A    +    K   KP +  FLG +  V RD NV++  +L+E A 
Sbjct: 250 GSTELIVVVSKPPQKATMENLKEEFKKCRKPVIVNFLGSSQPVKRDGNVYYTDTLEETAL 309

Query: 311 LACLLSRVTARRNAIAPV---------------SSGFICGLYTGGTLAAEAAGLLAGHLG 355
            A  L+  T   +   P                  G++  LYTGGTL  EAA +    L 
Sbjct: 310 KALELAGETVDDSVAVPEDILEDIRRERELHRHKGGYMRALYTGGTLGTEAAIICRDILS 369

Query: 356 VEADDTHQHGMMLDAD-----SHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQV 410
               +    G+   AD      + I+DLG D +T+G+PHPMI+P ++NQ +    A P+ 
Sbjct: 370 GLTTNLTVPGVEKMADYNVSAKNCILDLGADEFTLGKPHPMIEPEMKNQRLLKEAADPET 429

Query: 411 RVLLLDVVIGFGATADPAASLVSAWQKACA-ARLDNQPLYAIATVTGTERDPQCRSQQIA 469
            V+LLD V+G+G  ADPA + +    KA   A    + +  +A+VTGT+ DPQ R +QI 
Sbjct: 430 AVILLDFVLGYGVNADPAGNTLYEIDKAREIAESQGRHITIVASVTGTDEDPQNREEQIR 489

Query: 470 TLEDAGIAVVSSLPEATLLAAALIH 494
            L+D G+ V+ S  +A   A  ++ 
Sbjct: 490 VLKDHGVLVLPSNAQAVRAAVEIVK 514


>UniRef50_A6TL44 FdrA family protein n=3 Tax=Clostridiales RepID=A6TL44_ALKMQ
          Length = 525

 Score =  290 bits (743), Expect = 9e-77,   Method: Compositional matrix adjust.
 Identities = 180/525 (34%), Positives = 292/525 (55%), Gaps = 34/525 (6%)

Query: 6   IKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDIC 65
           I+K  + DSV+LM+I++++ +   + +V V MGT  NK L       + +     PND  
Sbjct: 7   IRKNTYYDSVTLMLITKEVKKLPGIQEVLVGMGTELNKELASHLSLSNKEIQGLNPNDFF 66

Query: 66  VAIRSEAADAGIAQAIMQQLEEAL-KQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
           V   + ++D  + +A++++++  L K+  QG G  +  T      +A +   DANL L+S
Sbjct: 67  VTALA-SSDLSM-EAVLKEVDTLLTKKKTQGDGDYRPPT----LGAALKYQLDANLVLVS 120

Query: 125 VAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTP 184
           + GEYA +   +AL ++++VM+FSD +++ DE +LK  A+E+ LL+MGPDCGT++I   P
Sbjct: 121 IPGEYAFDEVEKALHQDIHVMLFSDQMSMADERRLKEIAKERQLLMMGPDCGTAIINQVP 180

Query: 185 LAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTAL 244
           LAFANV+ +GNIG++GASGTGIQE+   I   GEG++  IG GGRDL +E+GGI     +
Sbjct: 181 LAFANVVRKGNIGIVGASGTGIQEVSILIHRLGEGVSQVIGTGGRDLKKEIGGIMMQQGI 240

Query: 245 EMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASS 304
           E L  D ++ V+  +SKPP E V  +++  +  + KP V  F+G    +         ++
Sbjct: 241 EALQNDPETGVIVLISKPPDEEVAERVLALIAHSEKPVVVNFIGGHLNLIEKYGRTPCTT 300

Query: 305 LDEAARLACLLSRVTARRN-------------------AIAPVSSGFICGLYTGGTLAAE 345
           L++AA+ A  L +  A R+                    +      +I GLYTGGTLA E
Sbjct: 301 LEDAAQKAVALLKGQAPRDFNGFTLSQERVSKMVCNEVKVFHHQQSYIRGLYTGGTLANE 360

Query: 346 AAGLLAGHLGVEADDT-----HQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQL 400
              LL+  LG    ++     +Q   + ++  H  +DLG+D +T G+PHPMIDP+ R Q 
Sbjct: 361 TIKLLSEELGGIYSNSPLRPEYQLLNVEESFQHTCLDLGEDGFTRGKPHPMIDPSTRLQR 420

Query: 401 IADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDN--QPLYAIATVTGTE 458
                   +V ++L+D V+G+G+  DP   ++    +    RL+   + L  IA++ GTE
Sbjct: 421 FVKEANDEEVAMILMDFVLGYGSHEDPVGEMLPVIIEE-KRRLNQRGRHLCVIASICGTE 479

Query: 459 RDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQH 503
            DPQ   +    LE+AG+ V+ S  +A  LA+ ++   +   + H
Sbjct: 480 EDPQDLKKSQQRLEEAGVLVMPSNAQAARLASLIMKNQNLRRENH 524


>UniRef50_D1B8P5 FdrA family protein n=1 Tax=Thermanaerovibrio acidaminovorans DSM
           6589 RepID=D1B8P5_THEAS
          Length = 517

 Score =  287 bits (734), Expect = 8e-76,   Method: Compositional matrix adjust.
 Identities = 193/512 (37%), Positives = 276/512 (53%), Gaps = 43/512 (8%)

Query: 11  FQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNN--ATPNDICVAI 68
           + DSV+LM +++++   E V   S+ MGT AN  +L   GF   D +N  ATPND+ +A+
Sbjct: 16  YYDSVTLMRVAKEIGGMEGVSSASLSMGTDANLRILAAAGF---DVSNLSATPNDLIIAV 72

Query: 69  RSE--AADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVA 126
             E    D  +A+A  + L     +  Q  G S    + R  D A   +P+ANLA+ISVA
Sbjct: 73  MGEQDVLDLAVAKA-KEYLSNPPWRQGQDGGES---YKPRSLDGALTVMPEANLAVISVA 128

Query: 127 GEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLA 186
           G YA ++A   + ++LNVM++SDNV LE EI++K  A EKGLLVMGPDCGT +I G  + 
Sbjct: 129 GRYAGDVAMDCIAKDLNVMLYSDNVPLEKEIEVKRAAAEKGLLVMGPDCGTVVIRGVAIG 188

Query: 187 FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEM 246
            AN  P G + ++ A+GTG+QE+  Q+A  G G  H IG GGRD+  +VGGI    A  +
Sbjct: 189 MANSCPTGPVSIVAAAGTGLQEVHVQLARRGVGTLHGIGTGGRDVKSQVGGIMVEMASRL 248

Query: 247 LSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLD 306
           L  D + +VL  V KPPA  V  +I++  + + KP V  F+G   A      V+    L+
Sbjct: 249 LLEDHEVQVLVIVGKPPAPEVEERILHLARGSSKPVVLGFVG-GKAKGDQHPVYICRELE 307

Query: 307 EA-----------------ARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGL 349
           E                  A +   +  + A    I P   G++ GLY+GGTL  EA  +
Sbjct: 308 ETAAVAAALAKGEDVPQVRAAMDAQVEELKALAKRIGP-RKGYLRGLYSGGTLCYEAQLI 366

Query: 350 LAGHLGVEADDT--HQHGMMLD---ADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADL 404
               LG    +T   +H  + D   +  H I+D G+D +T GR HPMID +LR     + 
Sbjct: 367 ARDILGPIHSNTPLEEHLKLEDSLRSVEHTIVDFGEDEFTQGRLHPMIDVSLRASRFQEE 426

Query: 405 GAKPQVRVLLLDVVIGFGATADPAASLVSAWQKA---CAARLDNQPLYAIATVTGTERDP 461
              P+V V+L DVVIG+G   DPA  LV   +KA   C  R     +  +A+V GT  D 
Sbjct: 427 VKDPEVGVVLFDVVIGYGCHPDPATGLVEGIRKAKEICGDR-----VVFVASVCGTPDDV 481

Query: 462 QCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
           Q   +Q   LE+AG+ V+ S  +A+ LA+ L+
Sbjct: 482 QDADRQRRILEEAGVVVMDSNAKASRLASFLL 513


>UniRef50_D0WIW7 Protein FdrA n=1 Tax=Slackia exigua ATCC 700122 RepID=D0WIW7_9ACTN
          Length = 488

 Score =  286 bits (733), Expect = 1e-75,   Method: Compositional matrix adjust.
 Identities = 198/496 (39%), Positives = 271/496 (54%), Gaps = 26/496 (5%)

Query: 18  MIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGI 77
           M IS+KL++  ++  VSV MGT  NK +L   GF      +A PND+ +A   E  D+  
Sbjct: 1   MGISKKLNDLPDILSVSVSMGTDMNKQILIDGGFDASSIGDAGPNDLMIACSFE--DSVR 58

Query: 78  AQAIMQQLEEALK-QLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQ 136
            + ++  LE ALK Q+ Q    S+   + R    A + + DAN+A+ISV G YAA  A +
Sbjct: 59  EEDVLADLEAALKKQVTQKDRDSE---RPRTLTRAAEDV-DANIAVISVPGIYAAAEARK 114

Query: 137 ALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNI 196
           AL++ L+V+MFSDNV+L+DEI LK  A  KGLL+MGPDCGT    G    FAN +  G+I
Sbjct: 115 ALEKGLHVLMFSDNVSLDDEIALKDLAHGKGLLMMGPDCGTCAFQGVAFCFANAVQRGSI 174

Query: 197 GVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVL 256
           G++ ASGTG QE    +   G G++  IG GGRDLS EVGG   L A + L ADE +  +
Sbjct: 175 GIVSASGTGAQEAAVLLDSWGMGVSQIIGTGGRDLSIEVGGRMFLDAFDALEADEGTSHI 234

Query: 257 AFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARD--ENVWFASSLDEAARLACL 314
             +SKPP E V  K+ +    + KP VA FLG    VA D  E V F S +  A     L
Sbjct: 235 LLISKPPHETVARKVRDRAARSTKPVVACFLG---DVAEDLSETVLFKSDIVSAVDALAL 291

Query: 315 L--SRVTARRNAIAPV----SSGFICGLYTGGTLAAEAAGLLAGHL---GVEADDTHQHG 365
           L  S  +A   +   +       ++ GL+ GGTL  EA       L    V A+      
Sbjct: 292 LVDSSFSAPEESAIEIDCMPDGSYVRGLFCGGTLMEEAKMTFMSSLPDVDVYANSAKGGS 351

Query: 366 MMLDADS----HQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGF 421
           + LD  S    H  +DLGDD +T G+PHPMIDP  RN  IA   A  +  V+LLD V+G+
Sbjct: 352 ISLDDSSESRGHAFLDLGDDAFTQGKPHPMIDPQTRNARIAQEAADTETAVILLDFVLGY 411

Query: 422 GATADPAASLVSAWQKACAARLDN-QPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVS 480
           GA  DP  + + A  KA  + L++ + +  IA V GT+ DPQ +  Q   L   G+ V  
Sbjct: 412 GAHEDPVGAALPAIHKANVSCLESGRTMVFIAYVLGTDADPQDKQHQEEMLAQEGVLVCQ 471

Query: 481 SLPEATLLAAALIHPL 496
           +  +A  LAA+++  L
Sbjct: 472 TNVQAANLAASIVKGL 487


>UniRef50_D2L8W4 FdrA family protein n=1 Tax=Desulfovibrio sp. FW1012B
           RepID=D2L8W4_9DELT
          Length = 502

 Score =  249 bits (636), Expect = 2e-64,   Method: Compositional matrix adjust.
 Identities = 193/506 (38%), Positives = 276/506 (54%), Gaps = 58/506 (11%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           ++ A ++K  +QDSV LM ISR+ S+   V  V  ++GT +NK +L   G   D    AT
Sbjct: 2   LLQATVRKNQYQDSVRLMQISRQASQLPGVGKVLALLGTDSNKKVLADLGLMDDVVAAAT 61

Query: 61  PNDICVA-------------------IRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQA 101
            ND+ +                    +RS AA AG A+A  + LEEA+ +L+        
Sbjct: 62  ANDLVICVEAENAEAVAAALADVDGRLRSVAA-AGPAEANPKSLEEAVARLS-------- 112

Query: 102 LTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKT 161
                           AN A+IS+ G+ A      AL++ L+VM+FSDN++L DE +LK 
Sbjct: 113 ---------------GANFAMISLPGQLAKLDVVTALEQGLHVMLFSDNISLADEAELKA 157

Query: 162 RAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGIT 221
            A +KGLL+MGPDCGT++I G  LA ANV+  G IG+  ASGTGIQE+   I   G G++
Sbjct: 158 LAAKKGLLLMGPDCGTAIINGVALALANVVRRGEIGLAAASGTGIQEVTCLIDRFGGGVS 217

Query: 222 HAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKP 281
           HAIG+GGRDL +EVGG     A+ +L+AD  ++ L  +SKP A  V   +++  + +G  
Sbjct: 218 HAIGVGGRDLKKEVGGTMMRQAIRILAADPATKTLVVLSKPGAPEVMETVLDEARQSGLR 277

Query: 282 TVALFLGYTPAVARDENVWFASSLDEAARLACL------LSRVTARRNAIAPVSSG--FI 333
            V   LG   A A  E +   S+L+EAA  A L      L+     R   A +SSG  ++
Sbjct: 278 VVTCLLGGD-ASAAPEGMVCVSTLEEAA-FAALDRDLPPLAIPPGLRERAAALSSGRQYL 335

Query: 334 CGLYTGGTLAAEAAGLLAGHLGVEAD----DTHQHGMMLDADSHQIIDLGDDFYTVGRPH 389
            GLY+GGTL  E   LL   L ++++       + G  +    H  +DLG+D +T GRPH
Sbjct: 336 RGLYSGGTLCYETLFLLKDDLDIQSNVAIKPELKLGYPVKGTGHCCVDLGEDEFTQGRPH 395

Query: 390 PMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLY 449
           P+ID +LR + +A+  A P V+V+LLD+V+G+GA  +PAA L  A   A  AR D  P+ 
Sbjct: 396 PIIDLSLRLERLAEEMADPSVKVVLLDLVLGYGAHRNPAAELAEAIAAASQARPDGGPVV 455

Query: 450 AIATVTGTERDPQCRSQQIATLEDAG 475
            +  V GT+ DPQ    Q   L + G
Sbjct: 456 -LVHVCGTQADPQDLQAQEKLLAEVG 480


>UniRef50_A1SGR4 FdrA family protein n=1 Tax=Nocardioides sp. JS614
           RepID=A1SGR4_NOCSJ
          Length = 471

 Score =  248 bits (632), Expect = 6e-64,   Method: Compositional matrix adjust.
 Identities = 189/488 (38%), Positives = 258/488 (52%), Gaps = 55/488 (11%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
           H  ++ G + DSV+L+ +SR +     V    V M TP N  +L  TG   +    A PN
Sbjct: 8   HVELRPGAYADSVTLLQVSRVVQGLPGVLAAQVAMATPLNVEVL--TGMGFEVPAQAGPN 65

Query: 63  DICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           D+ VA+R EAADA    A +  +++AL+   +    +  +   R   SA ++ PDA +AL
Sbjct: 66  DLVVALRLEAADA--LPAALAGVDQALRDANRRDEGAATIAPPRTTASALRRTPDA-VAL 122

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG 182
           +SV G +A   A  A++   +VM+FSDNV LE E+ LK  A E+G+LVMGPDCGT+++ G
Sbjct: 123 VSVPGAHAFVEAMDAVEAGRDVMVFSDNVPLEQELALKRAAAERGVLVMGPDCGTAVVDG 182

Query: 183 TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALT 242
             L FANV+  G +G++ ASGTG Q+L + +  AG G+T A+G+GGRDLS EV G++   
Sbjct: 183 VGLGFANVVEPGPVGIVAASGTGCQQLLALLDHAGVGVTSALGVGGRDLSAEVRGLATRE 242

Query: 243 ALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG-----YTPA----- 292
           AL  L  D   E++  +SKPPA  V  +I     A   P     LG      T A     
Sbjct: 243 ALRRLDEDPGVELIVLISKPPAADVTAEIEAYAAALATPVELALLGPGRPDLTAAAEAVL 302

Query: 293 --VARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLL 350
             + R+   W     D + R                 V+ G + GL+ GGTLA+EAA L+
Sbjct: 303 RRLGREVPAWPVDPPDVSPR-----------------VNPGALRGLFVGGTLASEAA-LV 344

Query: 351 AGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQV 410
           AG L            + +AD H  +D GDD YT GR HPMIDP++R + +A   A P  
Sbjct: 345 AGEL------------LGEADGHTFVDFGDDEYTTGRAHPMIDPSIRLEHLARAAADPTT 392

Query: 411 RVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIAT 470
            VLLLDVV+G GA  DPAASL  A                +  V GT  DPQ R +Q+  
Sbjct: 393 GVLLLDVVLGHGAEPDPAASLAPALAGVAQ--------PVVVAVVGTAGDPQGRDRQVRA 444

Query: 471 LEDAGIAV 478
           L DAG  V
Sbjct: 445 LVDAGAEV 452


>UniRef50_D1A7Z1 FdrA family protein n=2 Tax=Actinomycetales RepID=D1A7Z1_THECD
          Length = 480

 Score =  240 bits (613), Expect = 8e-62,   Method: Compositional matrix adjust.
 Identities = 177/474 (37%), Positives = 243/474 (51%), Gaps = 26/474 (5%)

Query: 6   IKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDIC 65
           ++ G ++DSV+L+ +SR+L+  E +    V M T  N  LL   GF   +   A P+D+ 
Sbjct: 7   VQSGRYRDSVTLLRVSRELAGREGITAAMVAMATEPNLDLLRRRGFAVPE--GAGPDDLV 64

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKL---PDANLAL 122
           VAIR   AD    +   + LE  L      +          R   A  +L   P   LAL
Sbjct: 65  VAIRG--ADEASVREARRVLEGLLADDPAPAARHAPQDDPPRTTGAAARLLAEPAGGLAL 122

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG 182
           +SV G YA   A  AL+  LNVM+ S +V L  E+ LK  A  +GL+VMGP CGT++I G
Sbjct: 123 VSVPGRYAFIEAMDALNAGLNVMVCSGDVPLHQEVALKEAAGRRGLIVMGPGCGTAVIGG 182

Query: 183 TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALT 242
             L FAN +  G + ++ ASGTG Q++   +  AG G+ H +G+GGRDLS EV G S L 
Sbjct: 183 AGLGFANAVRPGPVSIVAASGTGAQQVMCLLDAAGVGVRHVLGVGGRDLSAEVSGRSTLA 242

Query: 243 ALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPT-VALFLGYTPAVARDENVWF 301
           AL  L  D  +E++A V+ PPA  V   + +A +    P   A+    +P +        
Sbjct: 243 ALAALDEDPATELIAVVAGPPAPRVADLVHSAARRLDTPVHFAMLAEDSPDLTAATERLL 302

Query: 302 ASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDT 361
           ++      R  C      A R A  PV+ G + GL+TGG L AEAA +    LG +    
Sbjct: 303 SALGRRVPRWPCW----PAARPA-GPVAPGALRGLFTGGALRAEAALIARRMLGPD---- 353

Query: 362 HQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGF 421
                 L    H++IDLG D    GR HPMIDP  R + +A   A P  RV+LLDV++G 
Sbjct: 354 ------LACGGHRLIDLGADACARGRAHPMIDPAPRLEHLAAAAADPSCRVVLLDVLLGQ 407

Query: 422 GATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAG 475
           GA  DPAA L  A + A A R D   L  + ++ GT  DPQ   +Q A L+ AG
Sbjct: 408 GADPDPAALLAPAIEAALAGRDD---LRVVVSLCGTPADPQGLGRQAAALQRAG 458


>UniRef50_D2S3V1 FdrA family protein n=8 Tax=Bacteria RepID=D2S3V1_9ACTO
          Length = 490

 Score =  221 bits (563), Expect = 6e-56,   Method: Compositional matrix adjust.
 Identities = 174/471 (36%), Positives = 246/471 (52%), Gaps = 24/471 (5%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
           H  ++ G + DSV LM +SR +S  E V  V V M TP N  L    G        A+P+
Sbjct: 8   HVSLRSGVYADSVRLMQVSRDVSAREGVTAVLVAMATPLNLEL--AAGMGLAPAEGASPD 65

Query: 63  DICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
            + VA+ +   DA  A         A ++ A G   +  L  V     A      A LA+
Sbjct: 66  QLLVAVSAVDDDALAAAVAAVDAALAARERAAGPAQTVPLRTVGAGLGALDGDGPA-LAV 124

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG 182
           +SV G+YA   A  A+    +V++FSD V +E E+ LK  A + G+LVMG DCGT++++G
Sbjct: 125 VSVPGQYAVAEAADAIAAGRSVLVFSDGVPVEHEVALKRAAHDAGVLVMGSDCGTAIVSG 184

Query: 183 TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALT 242
             L FANV+  G +G++ ASGTG Q++   +  AG G++H +G+GGRDLS  VGG++ L 
Sbjct: 185 LALGFANVVRRGPVGLVAASGTGAQQVSCLLDTAGVGVSHVLGVGGRDLSEAVGGLATLD 244

Query: 243 ALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFA 302
           AL +  AD  +E +  VSKPPA AV + +  A      P         PA    E+    
Sbjct: 245 ALALFDADPATERVLLVSKPPAPAVAVAVAEAAAELSVPV-------HPAALSAESPDLT 297

Query: 303 SSLDEAAR-LACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDT 361
           ++++   R +   +    +R  A+       + GL+ GGTLA EA  + A  LG    +T
Sbjct: 298 AAVEALLRDMGVAVPEWPSRPAALGAAPGAVLKGLFAGGTLADEAMLIAAPVLGDVRSNT 357

Query: 362 HQH-----GMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLD 416
                   G  L A  H ++D GDD  TVGR HPMIDPTLR + +A + A  +  V+L+D
Sbjct: 358 PLRPELDLGTDLVARGHVVVDFGDDALTVGRAHPMIDPTLRLEALARIAASGEPAVVLMD 417

Query: 417 VVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQ 467
           VV+G GA  DP ASLV A + A         L A+  + GTE DPQ  S+Q
Sbjct: 418 VVLGHGADPDPVASLVPALRAAG--------LPAVVALVGTEADPQGWSRQ 460


>UniRef50_C7QE97 FdrA family protein n=1 Tax=Catenulispora acidiphila DSM 44928
           RepID=C7QE97_CATAD
          Length = 629

 Score =  167 bits (423), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 122/366 (33%), Positives = 180/366 (49%), Gaps = 25/366 (6%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
           H  +++G + DSV+LM+  R ++    V  V V M T  N ALL   G+      +A P 
Sbjct: 20  HVEVRRGEYHDSVTLMLAGRAVAGVAGVGRVLVAMATELNVALLAELGYA--ALPDAGPG 77

Query: 63  DICVAIRSEAADAGIAQA----------IMQQLEEALKQLAQGSGSSQALTQVRRWDSAC 112
           D+ VA   E  D G A+            +  L ++L     GS ++       R D   
Sbjct: 78  DLVVAFTCEG-DGGDAEGSDSADATESAALAALADSLTPQPGGSITAPGHPHQGRPDQPA 136

Query: 113 QKLP-------DANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRARE 165
            +          A + LIS  G  +   A ++L+   + ++FSDN+ +  E++LK  AR 
Sbjct: 137 PRTTATALGRTSAPITLISTPGLASVAEAMESLEYGASPIIFSDNIPIHHEVRLKEEARR 196

Query: 166 KGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIG 225
           +GLLVMGPDCGT ++ GT LAFA ++  G I ++ ASGTG Q+L + +  AG GI H +G
Sbjct: 197 RGLLVMGPDCGTVVLHGTGLAFATIVRPGPISLVAASGTGAQQLMALLDAAGTGIHHCLG 256

Query: 226 LGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVAL 285
           +GGRDL+ +V G S L AL  L+ D  +E++  VSKPP   +  KI       GKP    
Sbjct: 257 VGGRDLTEQVAGRSTLAALTALADDPATELITVVSKPPHPTIAAKIQAHAATLGKPVHFA 316

Query: 286 FLGYTPAVARDENVWFASSLDEAA-----RLACLLSRVTARRNAIAPVSSGFICGLYTGG 340
           F+G       +      ++L   A     + A   +          P S+  I GL++GG
Sbjct: 317 FVGPNHPTLTESAEHILTALGHQAPQPWPQWAPTATTAAVATTEPMPPSAPMIRGLFSGG 376

Query: 341 TLAAEA 346
           TL AEA
Sbjct: 377 TLRAEA 382



 Score = 53.9 bits (128), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 45/101 (44%), Positives = 59/101 (58%), Gaps = 3/101 (2%)

Query: 375 IIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSA 434
           + D GDD YT GRPHPMID TLR++ +A+  A  +V V+LLDVV+G GA ADP A + +A
Sbjct: 500 LTDFGDDAYTRGRPHPMIDNTLRSRGVAEAAADERVGVVLLDVVLGRGAHADPGAEIAAA 559

Query: 435 WQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAG 475
              A   R     L  + ++ G   DPQ   +Q   L  AG
Sbjct: 560 IGAARGVRAG---LAVVVSLCGAAGDPQGLGRQAGVLAGAG 597


>UniRef50_C0XJA3 Putative uncharacterized protein (Fragment) n=1 Tax=Lactobacillus
           hilgardii ATCC 8290 RepID=C0XJA3_LACHI
          Length = 145

 Score =  101 bits (251), Expect = 9e-20,   Method: Composition-based stats.
 Identities = 58/147 (39%), Positives = 92/147 (62%), Gaps = 3/147 (2%)

Query: 18  MIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGI 77
           M++++ +S    V +V VMMGT ANK +    G   D+  +A PND+ + + ++  D  +
Sbjct: 1   MLLTKNISSMPGVKEVQVMMGTDANKDIFGEAGLLTDEAKSAEPNDMMIVLDADKKD--V 58

Query: 78  AQAIMQQLEEALKQLAQGSGSSQALTQV-RRWDSACQKLPDANLALISVAGEYAAELANQ 136
              +++Q+++ L  L+  S  S + ++    WD A + +PDANLA+ISV G YAA+  + 
Sbjct: 59  MDDVLKQIDKFLNDLSVKSDDSDSDSKKVTNWDDAMKSIPDANLAVISVPGLYAADEIDN 118

Query: 137 ALDRNLNVMMFSDNVTLEDEIQLKTRA 163
           ALD NLN  +FSDNV+LEDE +LK +A
Sbjct: 119 ALDHNLNAFVFSDNVSLEDESRLKKKA 145


>UniRef50_Q2TTV5 Putative uncharacterized protein n=1 Tax=Escherichia coli
           RepID=Q2TTV5_ECOLX
          Length = 192

 Score = 80.1 bits (196), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 57/143 (39%), Positives = 82/143 (57%), Gaps = 8/143 (5%)

Query: 11  FQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRS 70
           +QDSVSLM IS ++S+   +   SV+MGTP N   L   G  ++   NA+PND+ +A+  
Sbjct: 34  YQDSVSLMQISAQISKLPGIQQASVVMGTPNNLEQLRDAGLGNEI--NASPNDLVIAVMG 91

Query: 71  EAADAGIAQAIMQQ--LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGE 128
           E      A  + QQ    +   +   G  S + ++     + A +  P+ANLALISV G+
Sbjct: 92  EEDICNEALLLAQQRLTSKPDDETDCGIKSPEKVS----LEMALEAEPEANLALISVPGD 147

Query: 129 YAAELANQALDRNLNVMMFSDNV 151
           YAA  A +AL+  +NVMMFSDNV
Sbjct: 148 YAAAEAIKALNLGMNVMMFSDNV 170


>UniRef50_A3DLS0 Succinyl-CoA synthetase (ADP-forming) alpha subunit n=7
           Tax=cellular organisms RepID=A3DLS0_STAMF
          Length = 293

 Score = 65.1 bits (157), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 46/185 (24%), Positives = 97/185 (52%), Gaps = 9/185 (4%)

Query: 111 ACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQLKTRAREKGLL 169
           A + + + + ++I V  ++A++   +A+D ++  +++ ++ + + +E++    A++K + 
Sbjct: 60  AVENIGEIDASIIFVPAKFASDAVFEAIDADIKTIVVITEGIPVHEELEFVRYAKKKNIT 119

Query: 170 VMGPDCGTSMIAG-TPLAF--ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGL 226
           ++GP+    M+ G T +    A+V   GNIG+I  SGT   E+  +I   G GI+  IGL
Sbjct: 120 IIGPNTPGIMVPGETKIGIMPAHVFKPGNIGLISRSGTLTYEIAREIGKKGYGISTVIGL 179

Query: 227 GGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEA-VRLKIVNAMKATGKPTVAL 285
           GG  ++    G++ + A ++ + D  ++ +  + +   +A  R     A     KP VA 
Sbjct: 180 GGDPVT----GLNFIEAYDLFAKDPITKAVVLIGEIGGDAEERFAKYYAELPVKKPVVAY 235

Query: 286 FLGYT 290
             G T
Sbjct: 236 IAGKT 240


>UniRef50_Q58643 Succinyl-CoA ligase [ADP-forming] subunit alpha n=65 Tax=cellular
           organisms RepID=SUCD_METJA
          Length = 294

 Score = 56.6 bits (135), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 49/201 (24%), Positives = 97/201 (48%), Gaps = 19/201 (9%)

Query: 98  SSQALTQVRRWDSACQ--KLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLE 154
             Q +  V  +D+  +  K  DAN ++I V   +A +   +A+D  +  +++ ++++ + 
Sbjct: 49  GGQNVHGVPVFDTVKEAVKETDANASVIFVPAPFAKDAVFEAIDAGIELIVVITEHIPVH 108

Query: 155 DEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMP-----EGNIGVIGASGTGIQEL 209
           D ++    A + G+ ++GP+  T  IA   +    ++P     EG++G++  SGT   E+
Sbjct: 109 DTMEFVNYAEDVGVKIIGPN--TPGIASPKVGKLGIIPMEVLKEGSVGMVSRSGTLTYEI 166

Query: 210 CSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSE--VLAFVSKPPAEAV 267
             QI  AG G++  +G+GG  +     G+     L++   D+++E  V+       AE  
Sbjct: 167 AHQIKKAGFGVSTCVGIGGDPIV----GLRYKEVLDLFEKDDETEAIVMIGEIGGGAEEE 222

Query: 268 RLKIVNAMKATGKPTVALFLG 288
             K +  MK   KP +    G
Sbjct: 223 AAKFIEKMK---KPVIGYIAG 240


>UniRef50_C9KQT1 Succinyl-CoA ligase [ADP-forming] subunit alpha n=1 Tax=Mitsuokella
           multacida DSM 20544 RepID=C9KQT1_9FIRM
          Length = 301

 Score = 50.4 bits (119), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 39/140 (27%), Positives = 74/140 (52%), Gaps = 8/140 (5%)

Query: 118 ANLALISVAGEYAAELANQALDRNLNVMM-FSDNVTLEDEIQLKTRAREKGLLVMGPDCG 176
           A  ++I V   +AA+   +A+D +L+V++  S+++ ++D I+++     +   ++GP+C 
Sbjct: 66  ATASVIYVPARFAADSIMEAVDADLDVVVCISEHIPVQDMIKVRRYMEGRKTHLIGPNCP 125

Query: 177 TSMIAGT---PLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
             + A      +    +  +G++GVI  SGT   E   Q+  AG G T AIG+GG     
Sbjct: 126 GILTADECKLGIIPGYIHRKGHVGVISRSGTLTYEATFQLTAAGIGQTTAIGIGG----D 181

Query: 234 EVGGISALTALEMLSADEKS 253
            V G   + AL++   D ++
Sbjct: 182 PVKGTDFIDALKLFKEDPET 201


>UniRef50_P53595 Malate--CoA ligase subunit alpha n=184 Tax=cellular organisms
           RepID=MTKB_METEA
          Length = 296

 Score = 50.1 bits (118), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 44/155 (28%), Positives = 76/155 (49%), Gaps = 18/155 (11%)

Query: 118 ANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQLKTRAR----EKGLLVMG 172
           A  ++  VA  +AA+   +A D  L  V   +D +  +D +++K   R    EK  +V+G
Sbjct: 66  ATTSITFVAPPFAADAIMEAADAGLKLVCSITDGIPAQDMMRVKRYLRRYPKEKRTMVVG 125

Query: 173 PDC------GTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGL 226
           P+C      G SM+   P    ++   G +GVI  SGT   E  +Q+   G GI+ ++G+
Sbjct: 126 PNCAGIISPGKSMLGIMP---GHIYLPGKVGVISRSGTLGYEAAAQMKELGIGISTSVGI 182

Query: 227 GGRDLSREVGGISALTALEMLSADEKSEVLAFVSK 261
           GG  ++    G S L  L +   D ++E +  + +
Sbjct: 183 GGDPIN----GSSFLDHLALFEQDPETEAVLMIGE 213


>UniRef50_A6TL45 Putative uncharacterized protein n=3 Tax=Clostridiales
           RepID=A6TL45_ALKMQ
          Length = 56

 Score = 49.3 bits (116), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 22/47 (46%), Positives = 29/47 (61%)

Query: 509 ENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ 555
           + + VINIGL SF  +L+      +H  W P AGGNKK+  LL RL+
Sbjct: 10  KQLKVINIGLESFHQDLKKQGVQSIHVDWRPTAGGNKKMVGLLARLK 56


>UniRef50_C0BZV5 Putative uncharacterized protein n=2 Tax=Clostridium hylemonae DSM
           15053 RepID=C0BZV5_9CLOT
          Length = 306

 Score = 47.4 bits (111), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 46/193 (23%), Positives = 89/193 (46%), Gaps = 22/193 (11%)

Query: 115 LPDANLALISVAGEYAAELANQALDRNLNVM-MFSDNVTLEDEIQLKTRAREKGLLVMGP 173
            P+   A++ V  ++  + A QALD  + ++ + ++ V + D +Q+  +A+     V+GP
Sbjct: 64  FPEIRAAMLLVPKQFVRDAAFQALDEGIRLLAVITEFVPVMDALQIVHKAKALDAQVVGP 123

Query: 174 DCGTSMIAGTPLAFANVMPE-----GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
           +  T  +     +   +MP+     G+IG+I  SGT   E  S +   G G++  +G+GG
Sbjct: 124 N--TIGVISPGKSKLGIMPDYIYGKGHIGIISRSGTLTHETASNLTFKGFGLSTCVGIGG 181

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFV-----SKPPAEAVRLKIVNAMKATGKPTV 283
                 V G+     +E  + D++++ +  +     +     A ++K +N      KP  
Sbjct: 182 ----DAVVGMDHADVIEYFAQDDETDAIVIIGEIGGTSEEMAAAKIKELNLK----KPVC 233

Query: 284 ALFLG-YTPAVAR 295
           A   G Y P   R
Sbjct: 234 AYIAGMYAPENKR 246


>UniRef50_Q3ADM2 Succinyl-CoA ligase [ADP-forming] subunit alpha n=5 Tax=cellular
           organisms RepID=Q3ADM2_CARHZ
          Length = 289

 Score = 47.0 bits (110), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 42/179 (23%), Positives = 88/179 (49%), Gaps = 13/179 (7%)

Query: 118 ANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCG 176
           AN +++ +   +  + A +A++  +  +++ S++V L D +++   A   G+ V+GP+  
Sbjct: 66  ANTSILFIPAPFVLDAALEAMEAGIKTIVIISEHVPLHDALKIMRVAEAYGVTVVGPNTF 125

Query: 177 TSMIAGTPLAFANVMP-----EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
             +  G  +A   +MP     +G +G++  SGT   ++  ++  AG G +  +GLGG  +
Sbjct: 126 GVISPG--IAKVGIMPNTIYQKGPVGIVARSGTLSYQIAYELTRAGLGQSTVVGLGGDRI 183

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
                G+S    +  L+ DE+++ +  V +    A   +    ++   KP VA   G T
Sbjct: 184 V----GLSLAEVILSLARDEETQGIVVVGEIGGTA-EEEAAEVIRHINKPVVAFIAGKT 237


>UniRef50_B8FZH7 CoA-binding domain protein n=1 Tax=Desulfitobacterium hafniense
           DCB-2 RepID=B8FZH7_DESHD
          Length = 292

 Score = 44.3 bits (103), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 39/132 (29%), Positives = 68/132 (51%), Gaps = 13/132 (9%)

Query: 105 VRRWDSACQKLP-DANLALISVAGEYAAELANQALDRNLNVMMFS-DNVTLEDEIQLKTR 162
           VRR   A Q+ P +A+L ++       A L  +ALD  + V++ + + + L + +QL+  
Sbjct: 57  VRR---AVQEHPIEASLLVVPPKAAKGAVL--EALDSGIKVIVVTAEGIPLHEMMQLRKI 111

Query: 163 AREKGLLVMGPDC------GTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALA 216
           A EK  +V+G +       G +M+   P     V   G +GV+  SG+   E+ ++I  A
Sbjct: 112 ALEKQAMVIGGNTTGIISTGKAMMGFFPYWLDRVYKPGRVGVMTRSGSLTNEVTAEIVKA 171

Query: 217 GEGITHAIGLGG 228
           G G +  +G+GG
Sbjct: 172 GFGPSSIVGVGG 183


>UniRef50_A9A4P2 CoA-binding domain protein n=9 Tax=Archaea RepID=A9A4P2_NITMS
          Length = 305

 Score = 44.3 bits (103), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 49/205 (23%), Positives = 96/205 (46%), Gaps = 19/205 (9%)

Query: 95  GSGSSQALTQVRRWDSACQKL--PDANLALISVAGEYAAELANQALDRNLNVMM-FSDNV 151
           G G  +   +V  ++S  + +   +A ++++ V  ++    A  AL+  + +++   ++V
Sbjct: 53  GKGGQKFDDKVPIYNSMQEAVDATNAKISIVFVPAKFFLSAAKDALEAGIKLLVAIPEHV 112

Query: 152 TLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPE-----GNIGVIGASGTGI 206
            + D ++    A++KG +V+GP+    MI    L    +MP      G I V+  SGT +
Sbjct: 113 PVRDTMETLELAKQKGAVVIGPNTPGIMIP--ELIKIGIMPPMPFKAGKIAVLSKSGTLL 170

Query: 207 QELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEA 266
            E+   +  AG G +  IG+GG      V G   + A +M+      E +  V +   ++
Sbjct: 171 YEISDALTNAGFGQSITIGIGG----DPVNGTRLIDAFDMVKDIPDLEGMVVVGEIGGDS 226

Query: 267 VRL---KIVNAMKATGKPTVALFLG 288
             +   +I+++     KPTVA   G
Sbjct: 227 EEMLAQRIIDS--GFNKPTVAYIAG 249


>UniRef50_D2L8W2 Putative uncharacterized protein n=1 Tax=Desulfovibrio sp. FW1012B
           RepID=D2L8W2_9DELT
          Length = 466

 Score = 43.9 bits (102), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 21/47 (44%), Positives = 26/47 (55%)

Query: 509 ENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ 555
           + + VIN+GL  F  ELQ  + P V   W P AGG+  L   L RLQ
Sbjct: 6   QELHVINVGLEGFYTELQEQNVPTVQVDWRPPAGGDVALIDKLARLQ 52


>UniRef50_B5I859 Succinyl-CoA ligase [ADP-forming] subunit alpha n=3
           Tax=Actinomycetales RepID=B5I859_9ACTO
          Length = 309

 Score = 43.9 bits (102), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 38/177 (21%), Positives = 80/177 (45%), Gaps = 10/177 (5%)

Query: 118 ANLALISVAGEYAAELANQALDRNLNV-MMFSDNVTLEDEIQLKTRAREKGLLVMGPDCG 176
           A++ ++ V   +A     +A+D  + + ++ ++ + + D +   + A++KG  ++GP+C 
Sbjct: 70  ADVTVVFVPPPFAGAAVVEAVDAGIALAVVITEGIPVHDSVAFTSYAKKKGTRIVGPNCP 129

Query: 177 TSMIAGTPLAF---ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
             +  G   A    A++   G IG++  SGT   +L  +  L   G +  +G+GG     
Sbjct: 130 GLITPGQSNAGIIPADITRSGRIGLVSKSGTLTYQLMYE--LRDIGFSTCVGIGG----D 183

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
            V G + +  L     D  +E++  + +   +A         +   KP V    G+T
Sbjct: 184 PVVGTTHIDCLAAFQDDPDTELIVLIGEIGGDAEERAAAYIREHVTKPVVGYIAGFT 240


>UniRef50_UPI00016B24F6 succinyl-CoA synthetase, alpha subunit n=2 Tax=candidate division
           TM7 RepID=UPI00016B24F6
          Length = 286

 Score = 42.4 bits (98), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 44/207 (21%), Positives = 91/207 (43%), Gaps = 32/207 (15%)

Query: 92  LAQGSGSSQALTQVR-----RWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMM 146
           +  G+  +QA+++V      R     +K    ++++I V   +A     +A+   + +++
Sbjct: 35  IVAGTSPNQAISEVHGVPVFRTIDDIKKRFAIDISVIFVPAPHAKAAILEAIQAQIPLII 94

Query: 147 -FSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAF---ANVMPEGNIGVIGAS 202
             ++ V + D +++K +      +++GP+C   ++ G  L     A++   G+  ++  S
Sbjct: 95  CITEGVPVHDMLEIKQKLHRSRSVLIGPNCPGVLLPGRQLLGIIPASLAVPGDTAIVSRS 154

Query: 203 GTGIQELCSQIALAGEGITHAIGLGGRDLS-----------------------REVGGIS 239
           GT   E  S +  AG G  + IG+GG  +S                        E+GGIS
Sbjct: 155 GTLTYEAMSLLTQAGFGQRYIIGIGGDMISGSSFVDCLQLFQNDPSVKRIVMIGEIGGIS 214

Query: 240 ALTALEMLSADEKSEVLAFVSKPPAEA 266
            +TA + +       V A+++   A A
Sbjct: 215 EITAADYIKQSINKPVYAYIAGHSAPA 241


>UniRef50_Q65SV2 Succinyl-CoA ligase [ADP-forming] subunit alpha n=1 Tax=Mannheimia
           succiniciproducens MBEL55E RepID=Q65SV2_MANSM
          Length = 289

 Score = 41.2 bits (95), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 33/150 (22%), Positives = 71/150 (47%), Gaps = 12/150 (8%)

Query: 118 ANLALISVAGEYAAELANQALDRNLNVMM-FSDNVTLEDEIQLKTRAREKGLLVMGPDCG 176
           A   +I V   +  +   +A+   L +++  ++ +   D +Q+K +  E G++++GP+C 
Sbjct: 66  ATATVIYVPAPFCKDAILEAIAAGLKLIVCITEGIPTLDMLQVKQKLDESGVVMIGPNCP 125

Query: 177 TSMIAGTPLAFANVMP-----EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
             ++         +MP     +G +G++  SGT   E   Q    G G +  +G+GG  +
Sbjct: 126 GIIVPDE--CKIGIMPGYIHKKGRVGIVSRSGTLTYEAVKQTTDEGFGQSACVGIGGDPI 183

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSK 261
                G + +  L++  AD K+E +  + +
Sbjct: 184 P----GSNFIDILKLYQADPKTEAIVMIGE 209


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q47208 Protein fdrA n=96 Tax=Proteobacteria RepID=FDRA_...   721   0.0  
UniRef50_D1AQ78 FdrA family protein n=1 Tax=Sebaldella termitidi...   699   0.0  
UniRef50_C5BXU8 FdrA family protein n=1 Tax=Beutenbergia caverna...   650   0.0  
UniRef50_C0WN22 Membrane protein n=1 Tax=Lactobacillus buchneri ...   645   0.0  
UniRef50_A6TL44 FdrA family protein n=3 Tax=Clostridiales RepID=...   620   e-176
UniRef50_UPI000182709D FdrA family protein n=1 Tax=Enterobacter ...   606   e-172
UniRef50_P77187 Uncharacterized protein yahF n=55 Tax=Proteobact...   591   e-167
UniRef50_C0D6C1 Putative uncharacterized protein n=1 Tax=Clostri...   574   e-162
UniRef50_Q2RGM5 FdrA n=1 Tax=Moorella thermoacetica ATCC 39073 R...   571   e-161
UniRef50_Q7BSA0 YahF/FdrA-like protein n=3 Tax=Proteobacteria Re...   565   e-159
UniRef50_C2GZK2 Bacterial FdrA protein n=28 Tax=Bacteria RepID=C...   562   e-158
UniRef50_A8VR79 Phage Terminase n=3 Tax=Firmicutes RepID=A8VR79_...   560   e-158
UniRef50_B9KYM7 Protein fdrA n=1 Tax=Thermomicrobium roseum DSM ...   560   e-158
UniRef50_Q0TAN3 YahF/FdrA-like protein n=18 Tax=Gammaproteobacte...   549   e-154
UniRef50_C1D754 YahF/FdrA-like protein n=1 Tax=Laribacter hongko...   536   e-151
UniRef50_B0VJR0 FdrA n=1 Tax=Candidatus Cloacamonas acidaminovor...   536   e-150
UniRef50_D1B8P5 FdrA family protein n=1 Tax=Thermanaerovibrio ac...   535   e-150
UniRef50_D0WIW7 Protein FdrA n=1 Tax=Slackia exigua ATCC 700122 ...   521   e-146
UniRef50_D2L8W4 FdrA family protein n=1 Tax=Desulfovibrio sp. FW...   487   e-136
UniRef50_D1A7Z1 FdrA family protein n=2 Tax=Actinomycetales RepI...   454   e-126
UniRef50_A1SGR4 FdrA family protein n=1 Tax=Nocardioides sp. JS6...   434   e-120
UniRef50_D2S3V1 FdrA family protein n=8 Tax=Bacteria RepID=D2S3V...   406   e-112
UniRef50_C7QE97 FdrA family protein n=1 Tax=Catenulispora acidip...   335   2e-90
UniRef50_A3DLS0 Succinyl-CoA synthetase (ADP-forming) alpha subu...   185   3e-45
UniRef50_P53595 Malate--CoA ligase subunit alpha n=184 Tax=cellu...   174   7e-42
UniRef50_Q58643 Succinyl-CoA ligase [ADP-forming] subunit alpha ...   167   8e-40
UniRef50_C9KQT1 Succinyl-CoA ligase [ADP-forming] subunit alpha ...   167   9e-40
UniRef50_Q3ADM2 Succinyl-CoA ligase [ADP-forming] subunit alpha ...   167   1e-39
UniRef50_Q2TTV5 Putative uncharacterized protein n=1 Tax=Escheri...   161   5e-38
UniRef50_C0BZV5 Putative uncharacterized protein n=2 Tax=Clostri...   159   3e-37
UniRef50_C0XJA3 Putative uncharacterized protein (Fragment) n=1 ...   156   2e-36
UniRef50_A6TL45 Putative uncharacterized protein n=3 Tax=Clostri...    77   2e-12

Sequences not found previously or not previously below threshold:

UniRef50_Q65SV2 Succinyl-CoA ligase [ADP-forming] subunit alpha ...   158   5e-37
UniRef50_B5I859 Succinyl-CoA ligase [ADP-forming] subunit alpha ...   153   2e-35
UniRef50_UPI00016B24F6 succinyl-CoA synthetase, alpha subunit n=...   152   3e-35
UniRef50_B8DUE3 Succinyl-CoA ligase [ADP-forming] subunit alpha ...   136   2e-30
UniRef50_P71558 Succinyl-CoA ligase [ADP-forming] subunit alpha ...   136   2e-30
UniRef50_B4UDP3 Succinyl-CoA ligase [ADP-forming] subunit alpha ...   135   4e-30
UniRef50_B2J366 CoA-binding domain protein n=7 Tax=Cyanobacteria...   133   1e-29
UniRef50_B5W071 CoA-binding domain protein n=5 Tax=Cyanobacteria...   129   3e-28
UniRef50_Q72A60 Succinyl-CoA ligase [ADP-forming] subunit alpha ...   129   4e-28
UniRef50_P53597 Succinyl-CoA ligase [GDP-forming] subunit alpha,...   125   5e-27
UniRef50_B4QTC9 GD20111 n=1 Tax=Drosophila simulans RepID=B4QTC9...   124   7e-27
UniRef50_C0CN70 Putative uncharacterized protein n=1 Tax=Blautia...   124   1e-26
UniRef50_A9A4P2 CoA-binding domain protein n=9 Tax=Archaea RepID...   123   2e-26
UniRef50_Q1IZE6 Succinyl-CoA ligase [ADP-forming] subunit alpha ...   122   3e-26
UniRef50_D2RT64 Succinyl-CoA synthetase, alpha subunit n=14 Tax=...   122   4e-26
UniRef50_B1Y9G0 Succinyl-CoA synthetase, alpha subunit n=4 Tax=c...   120   1e-25
UniRef50_A7HMU3 CoA-binding domain protein n=3 Tax=Thermotogacea...   119   2e-25
UniRef50_Q07LP7 Succinyl-CoA synthetase (ADP-forming) alpha subu...   119   3e-25
UniRef50_B8FZH7 CoA-binding domain protein n=1 Tax=Desulfitobact...   117   1e-24
UniRef50_A6DYT9 Succinyl-CoA ligase [ADP-forming] subunit alpha ...   115   4e-24
UniRef50_B8FRW5 Succinyl-CoA ligase [ADP-forming] subunit alpha ...   114   1e-23
UniRef50_Q0D1A9 Succinyl-CoA ligase alpha-chain, mitochondrial n...   113   2e-23
UniRef50_B1XIV2 Succinyl-CoA synthetase, alpha chain n=1 Tax=Syn...   113   2e-23
UniRef50_UPI000023DDE4 hypothetical protein FG07898.1 n=1 Tax=Gi...   111   6e-23
UniRef50_B4U9Z0 CoA-binding domain protein n=7 Tax=Bacteria RepI...   110   2e-22
UniRef50_UPI0001C319CC CoA-binding domain protein n=1 Tax=Conexi...   109   3e-22
UniRef50_Q2RLF6 Succinyl-CoA synthetase (ADP-forming) alpha subu...   108   6e-22
UniRef50_UPI000023F548 hypothetical protein FG11485.1 n=1 Tax=Gi...   102   3e-20
UniRef50_P74286 Succinyl-CoA synthetase n=7 Tax=Chroococcales Re...   101   8e-20
UniRef50_C4XQK6 Succinyl-CoA synthetase beta chain/succinyl-CoA ...   101   8e-20
UniRef50_A2QQL8 Contig An08c0100, complete genome n=3 Tax=Leotio...   100   2e-19
UniRef50_B6H3H8 Pc13g13290 protein n=23 Tax=cellular organisms R...    97   1e-18
UniRef50_Q0UIC0 Putative uncharacterized protein n=1 Tax=Phaeosp...    97   2e-18
UniRef50_B0JJU2 Succinyl-CoA synthetase alpha chain n=3 Tax=Chro...    94   1e-17
UniRef50_Q4PDB0 Putative uncharacterized protein n=1 Tax=Ustilag...    93   3e-17
UniRef50_B3QY35 ATP-citrate lyase/succinyl-CoA ligase n=13 Tax=C...    89   5e-16
UniRef50_C0RYI8 Succinyl-CoA synthetase beta chain n=6 Tax=Onyge...    88   1e-15
UniRef50_A7LNF0 ATP citrate lyase n=4 Tax=Toxoplasma gondii RepI...    87   2e-15
UniRef50_D2RGD1 Acetyl coenzyme A synthetase (ADP forming), alph...    87   2e-15
UniRef50_A9USL5 Predicted protein n=2 Tax=cellular organisms Rep...    87   2e-15
UniRef50_D1ZL53 Whole genome shotgun sequence assembly, scaffold...    86   3e-15
UniRef50_A8ZSQ9 CoA-binding domain protein n=1 Tax=Desulfococcus...    85   5e-15
UniRef50_A5D2I4 Succinyl-CoA synthetase, alpha subunit n=1 Tax=P...    85   5e-15
UniRef50_C5P5I2 Succinyl-CoA synthetase beta chain, putative n=9...    85   6e-15
UniRef50_Q251K7 Putative uncharacterized protein n=1 Tax=Desulfi...    85   7e-15
UniRef50_Q2LPK8 Succinyl-CoA synthetase, alpha subunit n=1 Tax=S...    83   3e-14
UniRef50_O93988 ATP-citrate synthase subunit 1 n=373 Tax=root Re...    82   4e-14
UniRef50_A9ICA6 Acetyl-CoA synthetase n=1 Tax=Bordetella petrii ...    82   5e-14
UniRef50_Q8TVZ2 Acyl-CoA synthetase (NDP forming) n=1 Tax=Methan...    80   2e-13
UniRef50_A3DLQ0 Acetyl-CoA synthetase (ADP-forming) alpha subuni...    80   2e-13
UniRef50_D1C4Q6 CoA-binding domain protein n=1 Tax=Sphaerobacter...    79   4e-13
UniRef50_Q4SU53 Chromosome 2 SCAF14024, whole genome shotgun seq...    79   5e-13
UniRef50_B8F999 CoA-binding domain protein n=1 Tax=Desulfatibaci...    78   9e-13
UniRef50_P16638 ATP-citrate synthase n=42 Tax=cellular organisms...    77   1e-12
UniRef50_Q330N6 Acetyl-CoA synthetase (ADP-forming) alpha subuni...    77   2e-12
UniRef50_C7MVA0 Acyl-CoA synthetase (NDP forming) n=1 Tax=Saccha...    76   4e-12
UniRef50_P53396 ATP-citrate synthase n=53 Tax=root RepID=ACLY_HUMAN    76   4e-12
UniRef50_Q89PN4 Blr3446 protein n=1 Tax=Bradyrhizobium japonicum...    75   6e-12
UniRef50_B6YXJ0 Acetyl-CoA synthetase II (NDP forming), alpha su...    75   7e-12
UniRef50_B8FK52 Acetyl coenzyme A synthetase (ADP forming), alph...    74   1e-11
UniRef50_Q46UX4 CoA-binding n=2 Tax=Cupriavidus RepID=Q46UX4_RALEJ     74   2e-11
UniRef50_C7LRJ9 CoA-binding domain protein n=1 Tax=Desulfomicrob...    72   7e-11
UniRef50_A0LDT0 CoA-binding domain protein n=6 Tax=Proteobacteri...    72   7e-11
UniRef50_B1L7G3 Acyl-CoA synthetase (NDP forming) n=1 Tax=Candid...    71   1e-10
UniRef50_Q1N4R6 Acyl-CoA synthetase (NDP forming) n=1 Tax=Berman...    71   1e-10
UniRef50_UPI0001BCDEDD succinyl-CoA synthetase, alpha subunit n=...    71   1e-10
UniRef50_C1XWJ3 Acyl-CoA synthetase (NDP forming) n=2 Tax=Meioth...    71   1e-10
UniRef50_Q2JX06 Acetyltransferase, GNAT family n=25 Tax=Bacteria...    70   2e-10
UniRef50_Q47QC9 Probable 6-carboxyhexanoate--COA ligase n=1 Tax=...    70   2e-10
UniRef50_C9R913 Acetyl coenzyme A synthetase (ADP forming), alph...    70   2e-10
UniRef50_A2SEI4 Acyl-CoA synthetase (ADP forming) n=13 Tax=Burkh...    70   2e-10
UniRef50_Q2NFU6 Predicted acyl-CoA synthetase n=4 Tax=Methanobac...    70   3e-10
UniRef50_D2LIT8 CoA-binding domain protein n=1 Tax=Rhodomicrobiu...    70   3e-10
UniRef50_A4YGK5 CoA-binding domain protein n=15 Tax=Archaea RepI...    69   4e-10
UniRef50_Q2BN19 Acetyltransferase, GNAT family protein n=1 Tax=N...    69   5e-10
UniRef50_B6YUE1 Acyl-CoA synthetase (NDP forming), large subunit...    69   5e-10
UniRef50_A2BLI1 Universally conserved protein n=1 Tax=Hypertherm...    69   5e-10
UniRef50_A1U3K8 GCN5-related N-acetyltransferase n=4 Tax=Gammapr...    69   6e-10
UniRef50_Q02CE8 CoA-binding domain protein n=2 Tax=Bacteria RepI...    69   6e-10
UniRef50_C8S7L3 CoA-binding domain protein n=1 Tax=Ferroglobus p...    69   6e-10
UniRef50_UPI0001B56A88 CoA-binding domain protein n=1 Tax=Strept...    69   6e-10
UniRef50_D0MJL0 Acetyl coenzyme A synthetase (ADP forming), alph...    69   7e-10
UniRef50_Q9UYT1 AcdA-4 acetate--coA ligase (ADP-forming), alpha ...    68   7e-10
UniRef50_B9L969 CoA binding domain protein n=2 Tax=Epsilonproteo...    68   8e-10
UniRef50_C4PZV0 ATP-citrate synthase, putative n=1 Tax=Schistoso...    68   8e-10
UniRef50_B4D5E1 Succinate--CoA ligase (GDP-forming) n=1 Tax=Chth...    68   8e-10
UniRef50_A8PI61 ATP-citrate synthase, putative n=1 Tax=Brugia ma...    68   1e-09
UniRef50_O28761 Putative uncharacterized protein n=1 Tax=Archaeo...    68   1e-09
UniRef50_C5A3W6 Acetyl-CoA synthetase (ADP forming), alpha chain...    67   1e-09
UniRef50_Q05FP1 Succinyl-CoA synthetase alpha subunit n=1 Tax=Ca...    67   2e-09
UniRef50_A6C207 Acetyl-CoA synthetase / acetyltransferase (GNAT)...    67   2e-09
UniRef50_B8D575 AcdA-1 acetate--coA ligase (ADP-forming), alpha ...    67   3e-09
UniRef50_B8CEH1 Acetyl-coa synthetase n=1 Tax=Thalassiosira pseu...    67   3e-09
UniRef50_A8ZSN5 CoA-binding domain protein n=3 Tax=Desulfobacter...    66   3e-09
UniRef50_C7DI26 CoA-binding domain protein n=1 Tax=Candidatus Mi...    66   3e-09
UniRef50_A1SKW5 CoA-binding domain protein n=3 Tax=Actinomycetal...    66   4e-09
UniRef50_Q0FX08 CoA-binding protein n=1 Tax=Roseovarius sp. HTCC...    66   4e-09
UniRef50_B6YUH0 Archaeal succinyl-CoA synthetase (NDP forming), ...    66   4e-09
UniRef50_Q2LVD4 Acetyl-CoA synthetase beta subunit n=1 Tax=Syntr...    65   6e-09
UniRef50_C5A3H6 Acetyl-CoA synthetase (ADP forming), alpha chain...    65   6e-09
UniRef50_C5A4T1 Acetyl-CoA synthetase (ADP forming), alpha chain...    65   6e-09
UniRef50_A3TZP5 Acetyl-CoA synthetase n=1 Tax=Oceanicola batsens...    65   7e-09
UniRef50_A0LL44 CoA-binding domain protein n=2 Tax=cellular orga...    65   9e-09
UniRef50_B8D4Z1 Acetyl-CoA synthetase n=1 Tax=Desulfurococcus ka...    65   9e-09
UniRef50_B8FE80 CoA-binding domain protein n=1 Tax=Desulfatibaci...    64   1e-08
UniRef50_Q979A5 Succinyl CoA synthetase alpha subunit n=2 Tax=Th...    64   1e-08
UniRef50_Q0S4P1 Probable acid--CoA ligase n=2 Tax=Rhodococcus Re...    64   1e-08
UniRef50_B5YGJ9 Acetyl-CoA synthetase n=1 Tax=Thermodesulfovibri...    64   1e-08
UniRef50_C5D0J6 CoA-binding domain protein n=1 Tax=Variovorax pa...    64   1e-08
UniRef50_C0QHB0 SucD4 n=1 Tax=Desulfobacterium autotrophicum HRM...    64   2e-08
UniRef50_Q3SEU0 Long-chain fatty-acid-CoA ligase n=4 Tax=Proteob...    64   2e-08
UniRef50_O28341 Putative uncharacterized protein n=3 Tax=Archaeo...    64   2e-08
UniRef50_D1ZXC1 Whole genome shotgun sequence assembly, contig_2...    64   2e-08
UniRef50_Q2Y4P6 Probable acetyl-CoA synthetase n=1 Tax=unculture...    64   2e-08
UniRef50_B2T9W3 GCN5-related N-acetyltransferase n=1 Tax=Burkhol...    63   3e-08
UniRef50_Q0S1K2 Possible acetyl-CoA synthetase n=10 Tax=Actinomy...    63   3e-08
UniRef50_Q89VS0 Bll0975 protein n=1 Tax=Bradyrhizobium japonicum...    63   3e-08
UniRef50_C3XDZ9 Putative uncharacterized protein n=1 Tax=Helicob...    63   4e-08
UniRef50_B5JNQ5 Acetyltransferase, GNAT family n=1 Tax=Verrucomi...    63   4e-08
UniRef50_C6C1C2 CoA-binding domain protein n=4 Tax=Desulfovibrio...    62   4e-08
UniRef50_B2TEE7 CoA-binding domain protein n=1 Tax=Burkholderia ...    62   5e-08
UniRef50_UPI0000E48CED PREDICTED: similar to ENSANGP00000012364 ...    62   5e-08
UniRef50_A2SRS8 CoA-binding domain protein n=2 Tax=Methanomicrob...    62   5e-08
UniRef50_Q13HH2 Putative CoA ligase n=1 Tax=Burkholderia xenovor...    62   6e-08
UniRef50_Q4TGD5 Chromosome undetermined SCAF3766, whole genome s...    62   6e-08
UniRef50_Q7MRU7 Putative uncharacterized protein n=1 Tax=Wolinel...    62   7e-08
UniRef50_C5EFZ7 Putative uncharacterized protein n=1 Tax=Clostri...    62   7e-08
UniRef50_Q58010 Uncharacterized protein MJ0590 n=11 Tax=Methanoc...    62   7e-08
UniRef50_A4J695 CoA-binding domain protein n=6 Tax=Peptococcacea...    62   8e-08
UniRef50_Q2YZQ4 Acyl-CoA synthetase (NDP forming) n=1 Tax=uncult...    62   8e-08
UniRef50_C6C0V7 CoA-binding domain protein n=2 Tax=Desulfovibrio...    61   9e-08
UniRef50_D1A2N2 CoA-binding domain protein n=2 Tax=Actinomycetal...    61   9e-08
UniRef50_A1RX15 CoA-binding domain protein n=2 Tax=Archaea RepID...    61   9e-08
UniRef50_D2R7V1 CoA-binding domain protein n=1 Tax=Pirellula sta...    61   9e-08
UniRef50_Q3AFE8 Acetyl-CoA synthase n=1 Tax=Carboxydothermus hyd...    61   9e-08
UniRef50_C5C5J4 GCN5-related protein N-acetyltransferase n=3 Tax...    61   9e-08
UniRef50_Q9NAT4 Acetyl-CoA synthetase n=3 Tax=Entamoeba RepID=Q9...    61   1e-07
UniRef50_A0LG54 CoA-binding domain protein n=1 Tax=Syntrophobact...    61   1e-07
UniRef50_Q39YX3 CoA-binding protein n=1 Tax=Geobacter metallired...    61   1e-07
UniRef50_C5A641 Acetyl-CoA synthetase (ADP forming), alpha chain...    61   1e-07
UniRef50_C0QHK1 SucC2 n=1 Tax=Desulfobacterium autotrophicum HRM...    61   1e-07
UniRef50_Q8PZY1 Acetyl-CoA synthetase, alpha subunit n=4 Tax=Arc...    61   1e-07
UniRef50_UPI0001C165DF GCN5-related N-acetyltransferase n=2 Tax=...    60   2e-07
UniRef50_A8ZZJ4 CoA-binding domain protein n=2 Tax=Desulfobacter...    60   2e-07
UniRef50_Q47QC0 Putative uncharacterized protein n=2 Tax=Nocardi...    60   2e-07
UniRef50_A4WJJ0 CoA-binding domain protein n=3 Tax=Pyrobaculum R...    60   2e-07
UniRef50_UPI0000510214 CoA-binding domain protein n=1 Tax=Brevib...    60   2e-07
UniRef50_Q2LS75 Acetyl-CoA synthetase beta subunit n=1 Tax=Syntr...    60   2e-07
UniRef50_C5U6W7 CoA-binding domain protein n=1 Tax=Methanocaldoc...    60   2e-07
UniRef50_B9Z1Z5 GCN5-related N-acetyltransferase n=1 Tax=Lutiell...    60   2e-07
UniRef50_C0D886 Putative uncharacterized protein n=1 Tax=Clostri...    60   2e-07
UniRef50_A8BPG2 Acetyl-CoA synthetase n=4 Tax=Hexamitidae RepID=...    60   2e-07
UniRef50_C0GIF8 CoA-binding domain protein n=1 Tax=Dethiobacter ...    60   3e-07
UniRef50_A8MDR5 CoA-binding domain protein n=7 Tax=Thermoprotei ...    60   3e-07
UniRef50_D1C154 CoA-binding domain protein n=1 Tax=Sphaerobacter...    60   3e-07
UniRef50_C6E214 CoA-binding domain protein n=3 Tax=Geobacter Rep...    60   3e-07
UniRef50_D0LBS1 CoA-binding domain protein n=2 Tax=Corynebacteri...    60   3e-07
UniRef50_Q0K2Q5 6-Carboxyhexanoate-CoA ligase n=2 Tax=Cupriavidu...    60   3e-07
UniRef50_B4RED1 Acetyl-CoA synthetase / acetyltransferase (GNAT)...    59   4e-07
UniRef50_C5CCL1 Acyl-CoA synthetase (NDP forming) n=8 Tax=Bacter...    59   4e-07
UniRef50_B8FCT2 CoA-binding domain protein n=1 Tax=Desulfatibaci...    59   4e-07
UniRef50_Q30WE4 Acetyltransferase, GNAT family n=4 Tax=Desulfovi...    59   5e-07
UniRef50_B8FIP4 CoA-binding domain protein n=1 Tax=Desulfatibaci...    59   5e-07
UniRef50_Q7VRY7 Acetyl-CoA synthetase n=3 Tax=Bordetella RepID=Q...    59   5e-07
UniRef50_D1ABG8 CoA-binding domain protein n=3 Tax=Streptosporan...    59   5e-07
UniRef50_Q72GY5 6-carboxyhexanoate-CoA ligase n=3 Tax=Thermus Re...    59   6e-07
UniRef50_UPI0001B582AA succinyl-CoA synthetase subunit alpha n=1...    59   7e-07
UniRef50_A0QZM0 CoA-binding protein n=3 Tax=Corynebacterineae Re...    58   7e-07
UniRef50_Q2LVF9 Acetyl-CoA synthetase beta subunit n=1 Tax=Syntr...    58   8e-07
UniRef50_B6R8H6 N-acetyltransferase n=1 Tax=Pseudovibrio sp. JE0...    58   8e-07
UniRef50_B8FGY7 CoA-binding domain protein n=1 Tax=Desulfatibaci...    58   8e-07
UniRef50_Q0W3R5 Acetyl-coa synthetase (ADP-forming), alpha subun...    58   9e-07
UniRef50_B8FN91 CoA-binding domain protein n=1 Tax=Desulfatibaci...    58   9e-07
UniRef50_UPI0001B555C7 CoA-binding protein n=1 Tax=Streptomyces ...    58   9e-07
UniRef50_A1WNK8 CoA-binding domain protein n=4 Tax=cellular orga...    58   1e-06
UniRef50_Q89GG9 Bll6376 protein n=1 Tax=Bradyrhizobium japonicum...    58   1e-06
UniRef50_Q3JJ59 Acetyltransferase, GNAT family n=65 Tax=Proteoba...    58   1e-06
UniRef50_A4FCG4 Acyl-CoA synthetase (NDP forming type) n=2 Tax=A...    58   1e-06
UniRef50_A9ISQ2 Acetyl-CoA synthetase n=4 Tax=Burkholderiales Re...    58   1e-06
UniRef50_Q7WC02 Putative acyl-CoA synthetase n=2 Tax=Bordetella ...    58   1e-06
UniRef50_UPI0001C30E25 CoA-binding domain protein n=1 Tax=Conexi...    58   1e-06
UniRef50_A9BTY3 CoA-binding domain protein n=8 Tax=cellular orga...    58   1e-06
UniRef50_Q2LUQ3 Acetyl-CoA synthetase / acetyltransferase (GNAT)...    58   1e-06
UniRef50_C1RIS6 Acyl-CoA synthetase (NDP forming) n=1 Tax=Cellul...    58   1e-06
UniRef50_B5IDQ5 CoA binding domain protein n=2 Tax=Aciduliprofun...    57   2e-06
UniRef50_C8WUT7 CoA-binding domain protein n=2 Tax=Alicyclobacil...    57   2e-06
UniRef50_B7X585 CoA-binding domain protein n=2 Tax=Comamonas tes...    57   2e-06
UniRef50_A3U075 CoA-binding n=1 Tax=Oceanicola batsensis HTCC259...    57   2e-06
UniRef50_Q2Y8E7 GCN5-related N-acetyltransferase n=2 Tax=Betapro...    57   2e-06
UniRef50_Q64CM7 Putative uncharacterized protein n=1 Tax=uncultu...    57   2e-06
UniRef50_B6AEK9 Acetyl-CoA synthetase, putative n=1 Tax=Cryptosp...    57   2e-06
UniRef50_A8M7Y9 CoA-binding domain protein n=4 Tax=Micromonospor...    56   3e-06
UniRef50_C8QZV8 CoA-binding domain protein n=2 Tax=Desulfobulbac...    56   3e-06
UniRef50_B9B8Y3 CoA binding domain protein n=1 Tax=Burkholderia ...    56   3e-06
UniRef50_A9A1Y1 CoA-binding domain protein n=6 Tax=Thaumarchaeot...    56   4e-06
UniRef50_C1DBF7 Probable acetyl-CoA synthetase n=1 Tax=Laribacte...    56   4e-06
UniRef50_A8ZY45 CoA-binding domain protein n=4 Tax=Desulfobacter...    55   5e-06
UniRef50_B2GFB1 Putative uncharacterized protein n=1 Tax=Lactoba...    55   5e-06
UniRef50_A3TZP8 Putative acetyl-CoA synthetase n=1 Tax=Oceanicol...    55   5e-06
UniRef50_C4XLT1 CoA-binding domain protein n=1 Tax=Desulfovibrio...    55   5e-06
UniRef50_A8KXI0 CoA-binding domain protein n=3 Tax=Frankia RepID...    55   6e-06
UniRef50_Q1LCA0 CoA-binding n=2 Tax=cellular organisms RepID=Q1L...    55   6e-06
UniRef50_A3K489 CoA-binding protein n=1 Tax=Sagittula stellata E...    55   6e-06
UniRef50_Q1M4T1 Putative pimeloyl-CoA synthetase n=1 Tax=Rhizobi...    55   7e-06
UniRef50_B6JHC2 N-acetyltransferase n=5 Tax=Rhizobiales RepID=B6...    55   7e-06
UniRef50_A8I8X8 ATP citrate lyase, subunit B n=1 Tax=Chlamydomon...    55   8e-06
UniRef50_C5BNQ0 Long-chain-fatty-acid--CoA ligase n=1 Tax=Teredi...    55   8e-06
UniRef50_Q0K4A4 Pimeloyl-CoA synthetase n=1 Tax=Ralstonia eutrop...    55   8e-06
UniRef50_C2APW0 Acyl-CoA synthetase (NDP forming) n=1 Tax=Tsukam...    55   8e-06
UniRef50_C5T5T1 CoA-binding domain protein n=1 Tax=Acidovorax de...    55   8e-06
UniRef50_Q0RF38 Putative uncharacterized protein n=1 Tax=Frankia...    54   1e-05
UniRef50_Q7WE41 Putative acetyl-CoA synthetase n=2 Tax=Bordetell...    54   1e-05
UniRef50_Q6FBA3 Pimeloyl-CoA synthetase n=2 Tax=Proteobacteria R...    54   1e-05
UniRef50_Q7WM17 Putative uncharacterized protein n=1 Tax=Bordete...    54   1e-05
UniRef50_Q2LV26 Acetyl-CoA synthetase n=1 Tax=Syntrophus aciditr...    54   1e-05
UniRef50_A3TKE9 Putative uncharacterized protein n=1 Tax=Janibac...    54   1e-05
UniRef50_Q12WB1 Acetyl-CoA synthetase (ADP-forming), alpha and b...    54   1e-05
UniRef50_A3TZG5 Putative pimeloyl-CoA synthetase n=1 Tax=Oceanic...    54   1e-05

>UniRef50_Q47208 Protein fdrA n=96 Tax=Proteobacteria RepID=FDRA_ECOLI
          Length = 555

 Score =  721 bits (1860), Expect = 0.0,   Method: Composition-based stats.
 Identities = 555/555 (100%), Positives = 555/555 (100%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT
Sbjct: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL
Sbjct: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI
Sbjct: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
           AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA
Sbjct: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW
Sbjct: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300

Query: 301 FASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADD 360
           FASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADD
Sbjct: 301 FASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADD 360

Query: 361 THQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIG 420
           THQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIG
Sbjct: 361 THQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIG 420

Query: 421 FGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVS 480
           FGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVS
Sbjct: 421 FGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVS 480

Query: 481 SLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPV 540
           SLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPV
Sbjct: 481 SLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPV 540

Query: 541 AGGNKKLARLLERLQ 555
           AGGNKKLARLLERLQ
Sbjct: 541 AGGNKKLARLLERLQ 555


>UniRef50_D1AQ78 FdrA family protein n=1 Tax=Sebaldella termitidis ATCC 33386
           RepID=D1AQ78_SEBTE
          Length = 573

 Score =  699 bits (1803), Expect = 0.0,   Method: Composition-based stats.
 Identities = 250/578 (43%), Positives = 364/578 (62%), Gaps = 28/578 (4%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           M++  IKK  +QDSV+LM+++++LS +E ++ +SVMMGTPANK +   +G + ++  +AT
Sbjct: 1   MLYTIIKKNSYQDSVNLMLLTKELSAAEGIEKISVMMGTPANKEIFANSGLYTEELESAT 60

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           PNDIC+ I +E  D G    I++ +E  LK  +  S   + +   R WDSA +KLPDANL
Sbjct: 61  PNDICIVIDTE--DEGKIDGILESIESFLKNQSSKSKG-KKIPVARTWDSALRKLPDANL 117

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           A+IS+ GEYAAE  ++AL++ LNV +FSDNV++EDE ++K  AR KGLLVMGPDCGT +I
Sbjct: 118 AIISIPGEYAAEETSKALEKGLNVFLFSDNVSIEDEKRIKEEARTKGLLVMGPDCGTGII 177

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            G PLAFANV+ +GNIG++GASGTGIQE+ + I+  G GIT AIG GGRDLS ++  ++A
Sbjct: 178 GGLPLAFANVIEKGNIGIVGASGTGIQEISTIISRKGYGITQAIGTGGRDLSAQIEAVTA 237

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           + AL++L+ADE ++V+ F+SKPPA  VR K++   K  GKP VA FLG       D NV+
Sbjct: 238 IEALKLLAADEDTDVIVFISKPPAPEVRDKVIETFKILGKPVVANFLGDKKRENHD-NVF 296

Query: 301 FASSLDEAARLACLLS------------RVTARRNAIAPVSSGFICGLYTGGTLAAEAAG 348
           +  +L++ A     ++             +   ++ I       I GLY GGTLAAE   
Sbjct: 297 YTHTLEDTALKTVEIAEKYKISEKNIRKEIKEVKDIIENKEQRSIKGLYCGGTLAAETGM 356

Query: 349 LLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKP 408
           ++  + G+E   +H  GMML  + H+IIDLGDDFYT GRPHPMIDP++R  ++ ++  +P
Sbjct: 357 IIRDYYGIEDSGSHDKGMMLHYNGHEIIDLGDDFYTQGRPHPMIDPSIRVDMVYEMAKRP 416

Query: 409 QVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQI 468
           +  V+LLD VIG+G   D A       ++        + +  IA++TGTE DPQ  S+Q 
Sbjct: 417 ETAVILLDNVIGYGGHEDMAGVFAPVIKEIKED-PAYKKIVFIASITGTENDPQKYSEQY 475

Query: 469 ATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAV-----------INIG 517
             LED+G  V  S  +AT +A  +I  L  +   +  +  E++ V           INIG
Sbjct: 476 KKLEDSGAVVCESNAQATRMAVEIIKSLEKSETNNIETGEESIEVKSNIINTEPVIINIG 535

Query: 518 LRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ 555
           L  FA  ++     V+ Y W+P AGG+K+LA +L++L+
Sbjct: 536 LGKFAETVKKYDAKVIQYNWAPTAGGDKRLAEILKKLR 573


>UniRef50_C5BXU8 FdrA family protein n=1 Tax=Beutenbergia cavernae DSM 12333
           RepID=C5BXU8_BEUC1
          Length = 562

 Score =  650 bits (1677), Expect = 0.0,   Method: Composition-based stats.
 Identities = 268/567 (47%), Positives = 358/567 (63%), Gaps = 19/567 (3%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           M+   IK   +QDSVSLM++S +LS  + V+ VS+MMGTPANK +   TGF  D+   A 
Sbjct: 1   MLQTIIKPNTYQDSVSLMMLSTQLSGLDAVERVSIMMGTPANKEIFRDTGFGSDELEGAG 60

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           P+D+ +A+  EA  AG A  I  ++ E LK  A  + S+    +VR  D A   LPDANL
Sbjct: 61  PSDLVIAL--EADGAGAADLISGRVAEFLKSQAS-AASATTYPRVRSLDRALTALPDANL 117

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           AL+S+ GE AA   ++ LD++L+V +FSDN+ ++DE++LK +ARE+GLL+MGPDCGT  +
Sbjct: 118 ALVSIPGEQAAPEIDRLLDKDLHVFVFSDNLAVDDEVRLKHKARERGLLMMGPDCGTGSL 177

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            G PLAF N++  G+IG++GASGTG QE+  QI  AG G++ AIGLGGRDLS +VG ++ 
Sbjct: 178 GGLPLAFTNIVTPGSIGIVGASGTGTQEVMVQIDRAGGGVSQAIGLGGRDLSEKVGAVTC 237

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           L AL  L AD  + V+  VSKPPA +VR  +++  +    P VA+ LG  PAV  D NV 
Sbjct: 238 LQALRALDADPGTSVITLVSKPPAPSVRETVLDVCQELATPVVAILLGEQPAVEVDGNVH 297

Query: 301 FASSLDEAARLACLLSRVTARRNAIA---PVSSGFICGLYTGGTLAAEAAGLLAGHLGVE 357
           FA++LDEAARLA  L+       A A         I GL+ GGTL +EAA LL+  LGV 
Sbjct: 298 FAATLDEAARLAVSLAGTVTDEEAPAVELAPGQRTITGLFCGGTLTSEAAILLSRGLGVP 357

Query: 358 ADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDV 417
            D  H  G ML  D H +IDLGDD YT GRPHPMIDP+LR Q+I D     Q+ VLLLDV
Sbjct: 358 TDAEHADGYMLHHDGHTVIDLGDDAYTQGRPHPMIDPSLRAQMIRDAFDDRQLAVLLLDV 417

Query: 418 VIGFGATADPAASLVSAWQKAC-AARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGI 476
           V GFG+  DPA ++V A +    AAR D + +  +A+V GTE+DPQ  S+Q  TL++AG+
Sbjct: 418 VTGFGSHEDPAGAIVGAIEAGREAARADGREVVVVASVCGTEKDPQPLSEQTRTLQEAGV 477

Query: 477 AVVSSLPEATLLAAALIHPLSPAAQQHTPSLL---------ENVAVINIGLRSFALELQS 527
            V+ S   AT  A  ++   S   ++ TP+ +         E   V+N+GL SFA  LQ 
Sbjct: 478 VVLGSNAAATRYALGVV---SRTGERRTPAEIPEPTRRLVSEAPRVVNVGLASFADTLQE 534

Query: 528 ASKPVVHYQWSPVAGGNKKLARLLERL 554
               VV Y WSP+AGGN +L R+L  L
Sbjct: 535 RGGQVVQYTWSPLAGGNARLQRILAAL 561


>UniRef50_C0WN22 Membrane protein n=1 Tax=Lactobacillus buchneri ATCC 11577
           RepID=C0WN22_LACBU
          Length = 587

 Score =  645 bits (1665), Expect = 0.0,   Method: Composition-based stats.
 Identities = 224/583 (38%), Positives = 333/583 (57%), Gaps = 32/583 (5%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           M+H  I+K  +QDS+ LM+++  L   + V++V VMMGTPANK +  T G   D+ + A 
Sbjct: 1   MLHTIIEKNSYQDSIVLMLLTNYLETLDGVNNVQVMMGTPANKDIFKTGGLATDELDEAK 60

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALK-QLAQGSGSSQALTQVRRWDSACQKLPDAN 119
           P+D+ + I +E+ D  +   ++ + ++ L  Q   G+ +  A  +V+ WD A +   DA 
Sbjct: 61  PSDMVIVIDTESDD--LIDEVVDKAKDYLDAQGKAGNENETADERVKTWDKALELGKDAP 118

Query: 120 LALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSM 179
           +ALISV G YAA    +ALD   NV  FSDNV++EDE +LK  A EKGL++MGPDCGT +
Sbjct: 119 VALISVPGVYAAVEVEKALDAGKNVFCFSDNVSMEDEARLKQMAHEKGLVLMGPDCGTGI 178

Query: 180 IAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGIS 239
             G PLAFAN + +G+IG++GASGTGIQE+ + I   G G+T+AIG GGRDL  ++ G +
Sbjct: 179 ANGIPLAFANRVRKGSIGMVGASGTGIQEVSTIIHKLGAGVTNAIGTGGRDLKADIQGTT 238

Query: 240 ALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENV 299
              ++ +L  D   +V+  +SKPPA  VR  +++ ++AT KP VA+FLG  P  + +E +
Sbjct: 239 FKDSVALLDQDPDVKVIVAISKPPAPEVRDDVLSLLRATNKPVVAIFLGEKP-TSHEEGL 297

Query: 300 WFASSLDEAARLACLLSRVTAR---------RNAIAPVSSGFICGLYTGGTLAAEAAGLL 350
           + A +L+E AR+A  L                +        +I G Y+GGTLA EAA L+
Sbjct: 298 YRAYTLEETARIAVDLLNGKTPGSYDDELKIPDIQLEPQQKYIKGYYSGGTLAYEAATLM 357

Query: 351 AGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQV 410
              L + A+D    G +L  + +++IDLGDD YT GRPHPMID T R +++ + G  PQ 
Sbjct: 358 NDALNLNAEDAGD-GFILQKEGYEVIDLGDDVYTQGRPHPMIDATKRKEMMVEAGNDPQT 416

Query: 411 RVLLLDVVIGFGATADPAASLVSAWQKACA-ARLDNQPLYAIATVTGTERDPQCRSQQIA 469
             +L+D+V+G+GA  + A  L  A +K  A A+   + L  I T+ GT+ DPQ  ++Q  
Sbjct: 417 AAILIDIVLGYGAHDNMAGELAPAIKKVIADAKNQGRNLPVIGTIVGTDLDPQNYAEQKD 476

Query: 470 TLEDAGIAVVSSLPEATLLAAALI--------HPLSPA---------AQQHTPSLLENVA 512
            LE AG+ +  S  +A   A AL+         P+ P            +    +L    
Sbjct: 477 ILEAAGVILCQSNAQAVKTALALVGKPIFGEPKPIRPKKSSTAVMPEVSEDLRQMLTATK 536

Query: 513 VINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ 555
            IN+GL SF+  +       V ++W PVAGGN  L + L  L 
Sbjct: 537 FINVGLDSFSEAINENGGDAVQFEWHPVAGGNVTLQKALNYLN 579


>UniRef50_A6TL44 FdrA family protein n=3 Tax=Clostridiales RepID=A6TL44_ALKMQ
          Length = 525

 Score =  620 bits (1599), Expect = e-176,   Method: Composition-based stats.
 Identities = 172/528 (32%), Positives = 282/528 (53%), Gaps = 30/528 (5%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           +   I+K  + DSV+LM+I++++ +   + +V V MGT  NK L       + +     P
Sbjct: 3   LKYAIRKNTYYDSVTLMLITKEVKKLPGIQEVLVGMGTELNKELASHLSLSNKEIQGLNP 62

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
           ND  V   + +      +A++++++  L +            +     +A +   DANL 
Sbjct: 63  NDFFVTALASSD--LSMEAVLKEVDTLLTKKKT---QGDGDYRPPTLGAALKYQLDANLV 117

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           L+S+ GEYA +   +AL ++++VM+FSD +++ DE +LK  A+E+ LL+MGPDCGT++I 
Sbjct: 118 LVSIPGEYAFDEVEKALHQDIHVMLFSDQMSMADERRLKEIAKERQLLMMGPDCGTAIIN 177

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
             PLAFANV+ +GNIG++GASGTGIQE+   I   GEG++  IG GGRDL +E+GGI   
Sbjct: 178 QVPLAFANVVRKGNIGIVGASGTGIQEVSILIHRLGEGVSQVIGTGGRDLKKEIGGIMMQ 237

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
             +E L  D ++ V+  +SKPP E V  +++  +  + KP V  F+G    +        
Sbjct: 238 QGIEALQNDPETGVIVLISKPPDEEVAERVLALIAHSEKPVVVNFIGGHLNLIEKYGRTP 297

Query: 302 ASSLDEAARLACLLSRVTARRN-------------------AIAPVSSGFICGLYTGGTL 342
            ++L++AA+ A  L +  A R+                    +      +I GLYTGGTL
Sbjct: 298 CTTLEDAAQKAVALLKGQAPRDFNGFTLSQERVSKMVCNEVKVFHHQQSYIRGLYTGGTL 357

Query: 343 AAEAAGLLAGHLGVEADD-----THQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLR 397
           A E   LL+  LG    +      +Q   + ++  H  +DLG+D +T G+PHPMIDP+ R
Sbjct: 358 ANETIKLLSEELGGIYSNSPLRPEYQLLNVEESFQHTCLDLGEDGFTRGKPHPMIDPSTR 417

Query: 398 NQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSA-WQKACAARLDNQPLYAIATVTG 456
            Q         +V ++L+D V+G+G+  DP   ++    ++        + L  IA++ G
Sbjct: 418 LQRFVKEANDEEVAMILMDFVLGYGSHEDPVGEMLPVIIEEKRRLNQRGRHLCVIASICG 477

Query: 457 TERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHT 504
           TE DPQ   +    LE+AG+ V+ S  +A  LA+ ++   +   + H 
Sbjct: 478 TEEDPQDLKKSQQRLEEAGVLVMPSNAQAARLASLIMKNQNLRRENHV 525


>UniRef50_UPI000182709D FdrA family protein n=1 Tax=Enterobacter cancerogenus ATCC 35316
           RepID=UPI000182709D
          Length = 513

 Score =  606 bits (1562), Expect = e-172,   Method: Composition-based stats.
 Identities = 203/511 (39%), Positives = 283/511 (55%), Gaps = 27/511 (5%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
              IKK  + DSVSLM +S K ++   V+   V M T  NK +L   G    +   A   
Sbjct: 4   KIVIKKNTWFDSVSLMSVSTKANKLPGVEQAVVAMATEMNKGVLHNLGLLTPELAEAKNG 63

Query: 63  DICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           D+ + I+ EAA+     AI     EAL    + +GS +A  +     SA    PDANLA+
Sbjct: 64  DLMIVIKGEAANDETLAAI-----EALFTRKESAGSHEA--RYATIASAKAHRPDANLAV 116

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG 182
           ISV G +AA  A QAL+ +LNVM+FSDNV+L+DE+ LK  A +KGLL+MGPDCGT++I G
Sbjct: 117 ISVNGTFAAREARQALENDLNVMLFSDNVSLDDELALKQLAHQKGLLMMGPDCGTAIING 176

Query: 183 TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALT 242
             L FAN +  G+IG++GASGTG QEL  +I   G G++  IG GGRDLS ++GG+  L 
Sbjct: 177 AGLCFANAVCRGSIGIVGASGTGSQELSVRIHEFGGGVSQLIGTGGRDLSEKIGGLMMLD 236

Query: 243 ALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFA 302
           A+ ML ADE ++ +  +SKPPA AV  K++   +A  KP +A FLG     A ++ + FA
Sbjct: 237 AIAMLEADENTQAIVLISKPPAPAVAEKVLARARACRKPVIACFLGRNAPPADEDGLQFA 296

Query: 303 SSLDEAARLACLLSRVTARRNAIAP--------------VSSGFICGLYTGGTLAAEAAG 348
               EAA  A LL+ +      + P                  +I GL+ GGTL  EA  
Sbjct: 297 RGTKEAALKAVLLTGIKQESLDLHPLNWPLIEEVRARQTPQQKYIRGLFCGGTLCDEAMF 356

Query: 349 LLAGHL-----GVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIAD 403
                       ++ D   +   +  + +H  +D GDD +T GRPHPMIDP+ R   +  
Sbjct: 357 AALEKYDDVYSNIQPDPAKRLSDINVSQAHTFLDFGDDDFTHGRPHPMIDPSNRITRLLQ 416

Query: 404 LGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACA-ARLDNQPLYAIATVTGTERDPQ 462
               P+V V+++D V+GFGA  DP   ++ A Q+A A A+ DN+PL  +  V GT++DPQ
Sbjct: 417 EARDPEVAVIVMDFVLGFGAHDDPVGVMIDAIQEAQAIAKADNRPLVILGYVLGTDQDPQ 476

Query: 463 CRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
             +QQ   L DAG+   SS     LLA   +
Sbjct: 477 SLAQQCERLTDAGVIWASSSTNTGLLAREFV 507


>UniRef50_P77187 Uncharacterized protein yahF n=55 Tax=Proteobacteria
           RepID=YAHF_ECOLI
          Length = 515

 Score =  591 bits (1524), Expect = e-167,   Method: Composition-based stats.
 Identities = 188/513 (36%), Positives = 271/513 (52%), Gaps = 27/513 (5%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           +   IK   + DSVSLM IS + ++ + V+   V M T  NK +L   G    +   A  
Sbjct: 3   VKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNKGVLKNLGLLTPELEQAKN 62

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
            D+ + I  ++      + ++ ++EE     AQ   S     +     SA + +P++NLA
Sbjct: 63  GDLMIVINGKS--GADNEQLLVEIEELFNTKAQ---SGSHEARYATIGSAKKHIPESNLA 117

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           +ISV G +AA  A QAL  +LNVM+FSDNV++EDE+ LK  A EKGLL+MGPDCGT++I 
Sbjct: 118 VISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAHEKGLLMMGPDCGTAIIN 177

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G  L F N +  GNIG++GASGTG QEL  +I   G G++  IG GGRDLS ++GG+  L
Sbjct: 178 GAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQLIGTGGRDLSEKIGGLMML 237

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
            A+ ML  D ++E++A +SKPPA AV  K++   +A  KP V  FL        ++ + F
Sbjct: 238 DAIGMLENDPQTEIIALISKPPAPAVARKVLERARACRKPVVVCFLDRGETPVDEQGLQF 297

Query: 302 ASSLDEAARLACLLSRVTAR---------------RNAIAPVSSGFICGLYTGGTLAAEA 346
           A    EAA  A +LS V                  R  + P    +I GL+ GGTL  E 
Sbjct: 298 ARGTKEAALKAVMLSGVKQENLDLHTLNQPLIADVRARLQP-QQKYIRGLFCGGTLCDET 356

Query: 347 AGLLAGHLG-----VEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLI 401
              +    G     ++ D   +   +  +  H  +D GDD +T G+PHPMIDPT R   +
Sbjct: 357 MFAVMEKHGDVYSNIQPDPEFRLKDINRSIKHTFLDFGDDDFTNGKPHPMIDPTNRISRL 416

Query: 402 ADLGAKPQVRVLLLDVVIGFGATADPAASLVSA-WQKACAARLDNQPLYAIATVTGTERD 460
            +    P+V V+++D V+GFG+  DP  S +    +    A  + + L  +A V GT+ D
Sbjct: 417 IEEARDPEVAVIVMDFVLGFGSHEDPVGSTIETIKEAKAIAAAEGRELIILAYVLGTDLD 476

Query: 461 PQCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
                QQ   L DAG+ + SS     LLA   I
Sbjct: 477 TPSLEQQSQMLLDAGVILASSSTNTGLLAREFI 509


>UniRef50_C0D6C1 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0D6C1_9CLOT
          Length = 517

 Score =  574 bits (1480), Expect = e-162,   Method: Composition-based stats.
 Identities = 176/514 (34%), Positives = 282/514 (54%), Gaps = 23/514 (4%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           + + +    ++DSV LM ++  + + E V++  V++ T ANK +L+  G   ++   ATP
Sbjct: 3   LKSKVFPNSYRDSVLLMKMAGMVRKIEGVENAEVIIATEANKGILEFNGLLTEEIRKATP 62

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
           ND+ V++ +   D  + +  +  +E+ +    +     +     +    A    P+A+LA
Sbjct: 63  NDLVVSVIA--GDETVIEKAIAAVEDMIFNGLEDDKGGKVTYSAKSIAGALAMEPEADLA 120

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           ++S+ G    + A + LD  +N+++FSDNV +EDE++LK +A E GL+VMGPDCGT+++ 
Sbjct: 121 ILSIPGPLVKKDAMKLLDSGVNLLIFSDNVPIEDELELKRKADEMGLMVMGPDCGTAIVR 180

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G  LAFAN + +G IG++ ASGTG+QE+   I   G+GI+HA+G G  D+   +GGIS  
Sbjct: 181 GASLAFANKVRQGKIGMVCASGTGLQEVAVLIHNLGQGISHALGTGSNDVKDAIGGISMK 240

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
             L+ L  D  +E++  VSKPP +A    +    K   KP +  FLG +  V RD NV++
Sbjct: 241 RGLKWLEQDGSTELIVVVSKPPQKATMENLKEEFKKCRKPVIVNFLGSSQPVKRDGNVYY 300

Query: 302 ASSLDEAARLACLLSRVTARRNAIAP---------------VSSGFICGLYTGGTLAAEA 346
             +L+E A  A  L+  T   +   P                  G++  LYTGGTL  EA
Sbjct: 301 TDTLEETALKALELAGETVDDSVAVPEDILEDIRRERELHRHKGGYMRALYTGGTLGTEA 360

Query: 347 AGLLAGHLGVEADDTHQHGMMLDAD-----SHQIIDLGDDFYTVGRPHPMIDPTLRNQLI 401
           A +    L     +    G+   AD      + I+DLG D +T+G+PHPMI+P ++NQ +
Sbjct: 361 AIICRDILSGLTTNLTVPGVEKMADYNVSAKNCILDLGADEFTLGKPHPMIEPEMKNQRL 420

Query: 402 ADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACA-ARLDNQPLYAIATVTGTERD 460
               A P+  V+LLD V+G+G  ADPA + +    KA   A    + +  +A+VTGT+ D
Sbjct: 421 LKEAADPETAVILLDFVLGYGVNADPAGNTLYEIDKAREIAESQGRHITIVASVTGTDED 480

Query: 461 PQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH 494
           PQ R +QI  L+D G+ V+ S  +A   A  ++ 
Sbjct: 481 PQNREEQIRVLKDHGVLVLPSNAQAVRAAVEIVK 514


>UniRef50_Q2RGM5 FdrA n=1 Tax=Moorella thermoacetica ATCC 39073 RepID=Q2RGM5_MOOTA
          Length = 520

 Score =  571 bits (1471), Expect = e-161,   Method: Composition-based stats.
 Identities = 207/523 (39%), Positives = 287/523 (54%), Gaps = 28/523 (5%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           +I   IK   +QDSV LM +S +L + + V   SV+M T  NK+ L   G    +   A 
Sbjct: 2   VIRWLIKPKMYQDSVKLMKLSAELRKQDGVKQASVIMATEMNKSTLQDIGMLVPEVAAAN 61

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
            +D+ + + ++  +   AQ  ++  E+ L + A+           +   SA + LP ANL
Sbjct: 62  ADDLAIIVAADTEEQ--AQKAVELAEKLLNR-AEVQQGETKQQFPKTLRSAVEALPGANL 118

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           ALISV G YAA  A +AL+  LNV +FSDNVTLEDE++LK    +KGLLVMGPDCGT++I
Sbjct: 119 ALISVPGTYAAAEALKALNLGLNVHLFSDNVTLEDEVRLKQIGTKKGLLVMGPDCGTAII 178

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            G PLAFANV+  G IG++GASGTGIQE    I   G GI+HAIG GGRDL  EVGG   
Sbjct: 179 DGVPLAFANVVARGKIGIVGASGTGIQEATVLIERLGGGISHAIGTGGRDLLDEVGGQMM 238

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           L  +++L  D  +EV+  +SKP       KI++ +K   KP V   L       +   V 
Sbjct: 239 LLGIDLLEDDPATEVILLISKPAGPRTANKILDRVKQCKKPVVVNLLKGDLNAIQSAGVV 298

Query: 301 FASSLDEAARLACLLS------------------RVTARRNAIAPVSSGFICGLYTGGTL 342
            A+++++AA  A  L+                  ++    + + P +  +I GL+TGGTL
Sbjct: 299 GAATIEDAAYKAVALANGEEAVAMPENYWGDYSKQIAMLESQLGP-NQRYIRGLFTGGTL 357

Query: 343 AAEAAGLLAGHLG-VEADDTHQHGMML----DADSHQIIDLGDDFYTVGRPHPMIDPTLR 397
           A EA  +L+  +G + ++   +  + L     +  H I+DLGDD +T GRPHPMIDP  R
Sbjct: 358 ADEAMVILSDIVGDIFSNIPLKPELKLPSARKSHKHTIVDLGDDEFTRGRPHPMIDPLPR 417

Query: 398 NQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGT 457
           N+ +    A P+V V+L DVV G+G+ ADPA  L  A  +A  A   N P   IA V GT
Sbjct: 418 NERLMQEYADPEVGVILCDVVTGYGSHADPAGELARAVARARDAYPSNNP-AVIAFVCGT 476

Query: 458 ERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
           E DPQ  S+Q+  LE  GI V+ S  EA   A  +I       
Sbjct: 477 EADPQPLSEQVKVLEKEGIFVLPSNAEAARAAGRIIKLHESRR 519


>UniRef50_Q7BSA0 YahF/FdrA-like protein n=3 Tax=Proteobacteria RepID=Q7BSA0_ACIAI
          Length = 514

 Score =  565 bits (1455), Expect = e-159,   Method: Composition-based stats.
 Identities = 199/506 (39%), Positives = 280/506 (55%), Gaps = 18/506 (3%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           I   +++  +QDSV+LM +S  L   + V + S+MMGT  N  ++   G      N+A P
Sbjct: 3   IVVEVRRNTYQDSVTLMRLSSDLLAEDGVTNASIMMGTAGNIEIMREGGLDAPALNDARP 62

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDA-NL 120
            D+ +AI + + DA  A+  +++   AL   A  +       Q R   S    + +  NL
Sbjct: 63  TDLVIAIVAASEDA--ARTAIEKAIAALNTDASTASDGGG-AQKRAISSVMGAVVEGVNL 119

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
            LISV GEYAA  A +AL   ++V +FSDNV++E EI LK  A  KGLL+MGPDCGT++I
Sbjct: 120 TLISVPGEYAAAEAMKALKAGMHVHLFSDNVSVEKEIALKDVAISKGLLMMGPDCGTAII 179

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            G P+ FAN +  G IGVI ASGTG QE+ S I   G GI+ A G GGRDLS  V G  A
Sbjct: 180 NGVPVGFANAVRRGRIGVIAASGTGAQEVTSLIHELGSGISQAFGTGGRDLSSAVKGRMA 239

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
             AL+ L  D+ ++V+  +SKPPA  V   I++  K T KP V  FLG    + RD  + 
Sbjct: 240 RFALKALLDDDMTDVIVLISKPPAPEVAASILDTAKGTSKPIVVCFLGGDSKMVRDHGLI 299

Query: 301 FASSLDEAARLACLLSRV--TARRNAIAPV------SSGFICGLYTGGTLAAEAAGLLAG 352
            A +L++AAR A        T  R A AP          ++ GL++GGT   EA  LL  
Sbjct: 300 PAETLEDAARQAVRAETGSDTGSRYAPAPTLPKLSKEQKYVRGLFSGGTFCYEALLLLRE 359

Query: 353 HLGVEADDTH-----QHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAK 407
            +G  + +T      +      +  H  ID G+D +TVGRPHPM+D   RN  I      
Sbjct: 360 FVGDVSSNTPINKQMKLKNNNISTGHVCIDFGEDEFTVGRPHPMLDFRFRNDRIVQEARD 419

Query: 408 PQVRVLLLDVVIGFGATADPAASLVSAWQKACA-ARLDNQPLYAIATVTGTERDPQCRSQ 466
           P+  V+LLD+V+G+GA A+PA +L+ A +KA   AR + + L  +A+V GT  D Q   Q
Sbjct: 420 PETAVILLDLVLGYGANANPAGALMPAIRKAMEVARAEGRTLPIVASVCGTSDDLQGLEQ 479

Query: 467 QIATLEDAGIAVVSSLPEATLLAAAL 492
           Q A L +AG+ ++SS  +A+  A  +
Sbjct: 480 QEAALREAGVTILSSNAQASRFAGKI 505


>UniRef50_C2GZK2 Bacterial FdrA protein n=28 Tax=Bacteria RepID=C2GZK2_ENTFA
          Length = 519

 Score =  562 bits (1449), Expect = e-158,   Method: Composition-based stats.
 Identities = 187/522 (35%), Positives = 273/522 (52%), Gaps = 26/522 (4%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           I   IK+  + DSV+LM IS + +E   V    + MGT  N  ++   G +    ++ T 
Sbjct: 3   IQTVIKENAYFDSVTLMTISTRANELAGVKTAMIGMGTDMNLEVIRNVGLYTPALDHVTT 62

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
               + I  +  D   ++ I+QQ++E   +  + + S       +  DSA  + PDANL 
Sbjct: 63  G--DLLIVLDLDDQANSEEILQQVDELFTKKKKTASSE---VTYKTLDSALHEEPDANLV 117

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           +ISV G++AA  A++ALD+  +VM+FSDNVT+++E+ LK +A EK L VMGPDCGT++I 
Sbjct: 118 VISVNGKFAAREAHKALDQQKHVMLFSDNVTVDEELALKQKAHEKELFVMGPDCGTAIIN 177

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G  L FAN +  G+IG++GASGTG QE+  QI   G GI+  IG GGRDLS E+GG+  L
Sbjct: 178 GVGLCFANEVRSGDIGIVGASGTGSQEVSVQIHKYGYGISQLIGTGGRDLSAEIGGLMML 237

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
             L+ L  DE+++ +  +SKPPA  V  KI+  +  + KP V  F+G      + +NV F
Sbjct: 238 DGLDALMVDEQTKAILLISKPPAPEVTEKILKKLAVSTKPVVIYFIGSEQTERKIDNVTF 297

Query: 302 ASSLDEAARLACLLSRVTARRNAI---------------APVSSGFICGLYTGGTLAAEA 346
           A+S  +A +     S+      ++                  S  F+ GL+ GGTL  E 
Sbjct: 298 ATSSLDAVQKVIQFSQTQEAETSLYQNPTGATLTAIQQQQAPSQKFVRGLFCGGTLCDEL 357

Query: 347 AGLLAGHLGVEADDTH-----QHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLI 401
              L         + H     Q      + +H +ID GDD +T GRPHPMIDPT R   I
Sbjct: 358 LYALTEVSDDVYSNIHKIPERQLANPDHSQAHTLIDFGDDRFTEGRPHPMIDPTSRITRI 417

Query: 402 ADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACA-ARLDNQPLYAIATVTGTERD 460
                 P+V VL LD  +G+G+  +P   L  A ++A A A+ D + L  I  V GTE D
Sbjct: 418 LQEAKDPEVAVLALDFELGYGSHENPVGVLAEALKEAKAIAKADGRELAIIGYVLGTEED 477

Query: 461 PQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQ 502
           PQ   +Q   LED  + VV S  +        +   +   Q+
Sbjct: 478 PQDIHEQRKILEDLEVLVVDSSHQLCEATKTFVKGANEHEQK 519


>UniRef50_A8VR79 Phage Terminase n=3 Tax=Firmicutes RepID=A8VR79_9BACI
          Length = 519

 Score =  560 bits (1443), Expect = e-158,   Method: Composition-based stats.
 Identities = 188/514 (36%), Positives = 278/514 (54%), Gaps = 30/514 (5%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
              I+K  + DSV+LM ++ K+ + + V D  V M T  NK L    G   D+   A  N
Sbjct: 4   QVIIRKNAYYDSVTLMSLASKIEQLDGVHDAIVAMATAMNKELAGDIGLVTDEVEAAGDN 63

Query: 63  DICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           D+ +A+ +E   A   +     +E A  +      + Q          A +   +ANLA+
Sbjct: 64  DLLLAVSAENEKA--LEEAFTAIEAAF-EAKSSQANKQTEKTYTNTKEALRDHEEANLAI 120

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG 182
           ISV+GE+AA  A  AL + L+VM+FSDNV++EDE +LK   R KGL VMGPDCGT+++ G
Sbjct: 121 ISVSGEFAAREAEIALKKGLHVMIFSDNVSVEDERRLKELGRNKGLFVMGPDCGTAILNG 180

Query: 183 TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALT 242
           T L FAN +  GNIG++ ASGTG+QE+  QI   G G++  IG GGRDLS+++GG+  L 
Sbjct: 181 TGLCFANSVRRGNIGLVAASGTGLQEVTVQIDRLGGGVSQGIGTGGRDLSKDIGGLMMLQ 240

Query: 243 ALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFA 302
            ++ L  D  ++V+  +SKPPA+ V+  ++  +KA+ KP V  F+   PA A      F 
Sbjct: 241 GIKALEEDPDTDVIVLISKPPAKEVQDLVLEQVKASRKPVVISFIDGDPAAAVSAGAIFG 300

Query: 303 SSLDEAARLACLLSRVTARRNAIAPV-------------------SSGFICGLYTGGTLA 343
            SL + A  A  LS+     +  A                     S   I GLY GGTL 
Sbjct: 301 YSLTDTAIKAVALSKGEEAPDKPADQFDKEAWETVLNGVREKRSDSQIDIRGLYGGGTLC 360

Query: 344 AEAAGLLAGH-LGVEADDTHQHGMML----DADSHQIIDLGDDFYTVGRPHPMIDPTLRN 398
           AEA  ++    L V+++   +    L    +++ H ++DLG+D +TVG+PHPMIDPT RN
Sbjct: 361 AEALSIMRQEGLSVKSNVAKREEEKLFNTRESEGHVLLDLGEDEFTVGKPHPMIDPTTRN 420

Query: 399 QLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTE 458
           Q +    A  +  V+L+D  +G+G+  DP    +   ++A   R++N  L  ++ V GT 
Sbjct: 421 QRLLQEAADEKTAVILMDFELGYGSHEDPVGVSLPFIEEA---RVNNPSLAIVSYVCGTA 477

Query: 459 RDPQCRSQQIATLEDAGIAVVSSLPEATLLAAAL 492
            DPQ      + L +AG+AV +S  EA  LA  L
Sbjct: 478 TDPQGLESAESRLREAGVAVANSNVEAVRLAVHL 511


>UniRef50_B9KYM7 Protein fdrA n=1 Tax=Thermomicrobium roseum DSM 5159
           RepID=B9KYM7_THERP
          Length = 514

 Score =  560 bits (1442), Expect = e-158,   Method: Composition-based stats.
 Identities = 200/506 (39%), Positives = 292/506 (57%), Gaps = 29/506 (5%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           ++   I+   + DSV+LM ++  ++    VD  +++MGT AN  LL  +G W +     +
Sbjct: 2   VVRIRIEPNSYFDSVALMAVASVVNRLPGVDLAALLMGTSANLELLRDSGLWDERLETVS 61

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           PND+ +A+R+  +D   A+  + +    L+  A+ S  S+A   +R   +A +++  A++
Sbjct: 62  PNDLVIAVRA--SDDAAAERAIDEAVHRLRSSARTSQVSEAKVTLRTLRTALRQVSQASV 119

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
             ISV G YA   A +AL  + +V +FSDNV +E+E++LK  A+E+GLL+MGPDCGT+ I
Sbjct: 120 VAISVPGPYAPIEAEEALRADRHVFLFSDNVPIEEEVRLKELAQERGLLLMGPDCGTAFI 179

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
           AG  L F N +  G IG++ A+GTG+Q+L S I   G GI+H IG GGRDL   VGG + 
Sbjct: 180 AGLGLGFMNAVRRGPIGIVAAAGTGLQQLASLIDWFGSGISHGIGTGGRDLDARVGGRTM 239

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           L  LE L+ D  ++V+  VSKPPA  V  K++    A GKP VA F+G T  V   E V 
Sbjct: 240 LAGLEALAHDPATQVIVLVSKPPAPEVAEKVLAFAAACGKPVVATFIGQTAPVT--EGVH 297

Query: 301 FASSLDEAARLAC------------------LLSRVTARRNAIAPVSSGFICGLYTGGTL 342
            A++L EAARLA                    L+RV A R+ +AP    ++ GLY+GGTL
Sbjct: 298 VAANLTEAARLAVHLATGQSLADLDLPRRQEALARVRAERSRLAPT-QRYLRGLYSGGTL 356

Query: 343 AAEAAGLLAGHLG-VEADDTHQHGMML----DADSHQIIDLGDDFYTVGRPHPMIDPTLR 397
             EA  LL   +G + ++   Q  + L     ++ H  +DLG D +TVGRPHPMID T+R
Sbjct: 357 CDEAMVLLQPRIGPIRSNIPLQPELRLTDPHRSEEHTFVDLGSDEFTVGRPHPMIDQTIR 416

Query: 398 NQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKAC-AARLDNQPLYAIATVTG 456
            +      A P V  ++LD+V+G+GA +DPAA L  A ++A   A    + L  I  + G
Sbjct: 417 LERFRREAADPTVAGIVLDLVLGYGAASDPAAELAPAIREARVEAERTGRILPCIVALVG 476

Query: 457 TERDPQCRSQQIATLEDAGIAVVSSL 482
           T+ DPQ  ++Q  TLEDAG  VV S 
Sbjct: 477 TQSDPQDYARQRRTLEDAGAIVVPSN 502


>UniRef50_Q0TAN3 YahF/FdrA-like protein n=18 Tax=Gammaproteobacteria
           RepID=Q0TAN3_ECOL5
          Length = 519

 Score =  549 bits (1414), Expect = e-154,   Method: Composition-based stats.
 Identities = 203/517 (39%), Positives = 288/517 (55%), Gaps = 30/517 (5%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           +   +    +QDSVSLM IS ++S+   +   SV+MGTP N   L   G  ++   NA+P
Sbjct: 3   VKYKVFSNLYQDSVSLMQISAQISKLPGIQQASVVMGTPNNLEQLRDAGLGNEI--NASP 60

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
           ND+ +A+  E      A  + QQ      +    + S     +    + A +  P+ANLA
Sbjct: 61  NDLVIAVMGEEDICNEALVLAQQ--RLTSKPDDETDSGIKSPEKVSLEMALEAEPEANLA 118

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           LISV G+YAA  A +AL+  +NVMMFSDNV++  E  +KT ARE+  +VMGPDCGT+++ 
Sbjct: 119 LISVPGDYAAAEAMKALNLGMNVMMFSDNVSIGQEKSIKTLARERQRIVMGPDCGTAIVN 178

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G PL FANV+  G IGVIGASGTG+QE+  +I   G GI+ A+G GG DLS E+GGIS L
Sbjct: 179 GIPLGFANVVKRGAIGVIGASGTGLQEVTCRIDQLGAGISQALGTGGHDLSEEIGGISML 238

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
            AL+ L+ D+++ V+  +SKPP+  V   I+   +A GKP V  FLG  P      N+  
Sbjct: 239 FALDALAQDDETRVIVLISKPPSPIVAQTILERAEACGKPVVVNFLGANPHDLARPNITA 298

Query: 302 ASSLDEAARLACLL---------------SRVTARRNAIA--PVSSGFICGLYTGGTLAA 344
           A++L  AA +A  L                 +T  +NA    P     I G++ GGT   
Sbjct: 299 ATTLASAANIAVALLNDQPIPAVETEISCDDLTMLQNACQRLPAHRQAIRGVFAGGTFCY 358

Query: 345 EAAGLLAGHLGVEADDTHQHG-----MMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQ 399
           EA  +        A +T   G      +  ++ H +ID+GDD +T G+PHPMIDPTLRNQ
Sbjct: 359 EAQLICQQKGFSAASNTPVAGNRALANIWQSEDHTLIDMGDDDFTRGKPHPMIDPTLRNQ 418

Query: 400 LIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTER 459
            + +        V+L D+V+G+GA+  PA+ L+          ++N PL  IA V GTE 
Sbjct: 419 RLLNELNDSHTAVVLFDLVLGYGASTTPASELLDQLSH---IDMNNAPL-LIAHVCGTEA 474

Query: 460 DPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPL 496
           DPQ RSQQI  L++AG+ + SS  +A L A+ +    
Sbjct: 475 DPQIRSQQIRALQNAGVIIASSNAQAALWASTVAQTQ 511


>UniRef50_C1D754 YahF/FdrA-like protein n=1 Tax=Laribacter hongkongensis HLHK9
           RepID=C1D754_LARHH
          Length = 512

 Score =  536 bits (1382), Expect = e-151,   Method: Composition-based stats.
 Identities = 203/514 (39%), Positives = 278/514 (54%), Gaps = 27/514 (5%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           +H  I +  ++DSV+LM +S  L+  + +   S +M TPAN ALL   G   D    A P
Sbjct: 3   LHLAILRNQYRDSVALMQLSAALARLDGITQASAVMATPANLALLSRAGLL-DTPPEAAP 61

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
           ND+ +A+  E        A +    +AL+     S    A         A  + PD+NLA
Sbjct: 62  NDLLIALEGE---EAAFDAALTHARQALEAKGGQSAGGPAELPANSLTMALSRQPDSNLA 118

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           LISV G YA   A +AL   LNVM+FSDNV+ EDE +LK  A   G +VMGPDCGT++I 
Sbjct: 119 LISVPGAYATAEAEKALRAGLNVMLFSDNVSGEDERRLKQLATGLGRIVMGPDCGTAIIH 178

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G PLAFANV   G IG +GASGTG+Q++ + I   GEGI+ AIG GG DL+  VGG+S L
Sbjct: 179 GVPLAFANVCRAGAIGCVGASGTGLQQITTLIDTLGEGISQAIGTGGHDLAESVGGLSML 238

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA-VARDENVW 300
             +  L+ D+ + V+  VSKPPAEAV  K+++A  A GKP V  FLG  PA + +  N+ 
Sbjct: 239 AGIRALAEDDATRVIVLVSKPPAEAVARKVLDAAIAAGKPVVVNFLGADPARLPQHANLH 298

Query: 301 FASSLDEAARLACLLSR---------------VTARRNAIAPVSSGFICGLYTGGTLAAE 345
           +A++L+ AAR+A    R                 A +  + P     + GLY+GGT   E
Sbjct: 299 YATTLESAARMAVACVRGEPLQDTPPQPHPETAAALKARLQP-QQTRLRGLYSGGTFCYE 357

Query: 346 AAGLLAGHLGVEADDT-----HQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQL 400
           A  +LA  L     +T          +  +  H +IDLGDD +T GRPHPMID  LRN+ 
Sbjct: 358 ATLMLADALPGLRSNTPTARAPAPDDVWHSAGHCLIDLGDDEFTRGRPHPMIDHRLRNER 417

Query: 401 IADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLD-NQPLYAIATVTGTER 459
                A   V V+L D+V+GFGA  DP A++     +      D  + +  +ATV GT  
Sbjct: 418 FLAEAADETVAVILFDIVLGFGAHDDPLAAMHDTLTEVRRLTADAGREVALVATVCGTAG 477

Query: 460 DPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
           DPQ   +Q A     G+ + +S  EA  LA A++
Sbjct: 478 DPQGFERQRAGFAALGVCLAASNAEAVALARAIV 511


>UniRef50_B0VJR0 FdrA n=1 Tax=Candidatus Cloacamonas acidaminovorans
           RepID=B0VJR0_9BACT
          Length = 505

 Score =  536 bits (1380), Expect = e-150,   Method: Composition-based stats.
 Identities = 190/511 (37%), Positives = 282/511 (55%), Gaps = 21/511 (4%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           I A I  G + DSV LM+ISR+L   + V +   ++ T  N+ +L  +    ++ N+A+ 
Sbjct: 3   IKAKIIAGKYLDSVKLMLISRELRSLKGVLEAVAIVATSENREILKASDMLAEEINSASE 62

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
           NDI + I+++ A    A   + + EE + + +    +   + Q    + A   L  A+L 
Sbjct: 63  NDIVIVIKADNAKN--AAEAINKAEELINKPSTNEYNQTPIPQAFTLEKAIATLGGADLC 120

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           LIS+AG+YAA  A +AL++ L++++FSDNV++EDE+ LK +A +KGLL+MGPDCGT+++ 
Sbjct: 121 LISIAGKYAAAEAEKALEKGLHILLFSDNVSIEDELSLKQKALKKGLLMMGPDCGTAILN 180

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G PLAFAN +P G IG++ ASGTG+QE+ + IA    GI+ A G GGRD  +E+GG+   
Sbjct: 181 GVPLAFANNVPRGKIGIVSASGTGLQEISTTIANLSGGISQAFGTGGRDGKKEIGGLMLT 240

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
             LE L  DE +EV+    KPP E V+ K+   +  + KP +A FL     V    N+++
Sbjct: 241 ACLEYLLEDENTEVIIVTGKPPCEEVQKKLWELISHSSKPVIANFL-IPMQVPELPNLYY 299

Query: 302 ASSLDEAARLACLLSRVTARRNAIAP------VSSGFICGLYTGGTLAAEAAGLLAGHLG 355
             SL E A  AC  + +  +   +A       +   ++ GLY+GGTL  EA  +   + G
Sbjct: 300 VRSLSETAFFACKKAGIEVKNAKLAEDFPLPKLRGPYLRGLYSGGTLCQEAIQVYLDNFG 359

Query: 356 VEADDT------HQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQ 409
            E  +        +         + IIDLG D +T+GRPHPMID +LR Q +A     P+
Sbjct: 360 CEPFNNVTDQAFFRLTDGWQTKENSIIDLGADEFTIGRPHPMIDYSLRLQKLAQEANDPK 419

Query: 410 VRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIA 469
           V ++LLDVV+GFGA  DPA  LV A QK  A       L  +  + GT+ DPQ R +Q  
Sbjct: 420 VGIILLDVVLGFGAHPDPAEELVPALQKLPAD------LVVVCHLLGTDGDPQNRQKQKK 473

Query: 470 TLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
            LE AG  V +S   A       +     A 
Sbjct: 474 ELEKAGAYVFTSHHSACEFVCQCLRSYRSAK 504


>UniRef50_D1B8P5 FdrA family protein n=1 Tax=Thermanaerovibrio acidaminovorans DSM
           6589 RepID=D1B8P5_THEAS
          Length = 517

 Score =  535 bits (1377), Expect = e-150,   Method: Composition-based stats.
 Identities = 187/515 (36%), Positives = 271/515 (52%), Gaps = 33/515 (6%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
              + +  + DSV+LM +++++   E V   S+ MGT AN  +L   GF   +  +ATPN
Sbjct: 8   RLEVVERTYYDSVTLMRVAKEIGGMEGVSSASLSMGTDANLRILAAAGFDVSNL-SATPN 66

Query: 63  DICVAIRSEAA--DAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           D+ +A+  E    D  +A    + L     +  Q  G S    + R  D A   +P+ANL
Sbjct: 67  DLIIAVMGEQDVLDLAVA-KAKEYLSNPPWRQGQDGGES---YKPRSLDGALTVMPEANL 122

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           A+ISVAG YA ++A   + ++LNVM++SDNV LE EI++K  A EKGLLVMGPDCGT +I
Sbjct: 123 AVISVAGRYAGDVAMDCIAKDLNVMLYSDNVPLEKEIEVKRAAAEKGLLVMGPDCGTVVI 182

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            G  +  AN  P G + ++ A+GTG+QE+  Q+A  G G  H IG GGRD+  +VGGI  
Sbjct: 183 RGVAIGMANSCPTGPVSIVAAAGTGLQEVHVQLARRGVGTLHGIGTGGRDVKSQVGGIMV 242

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
             A  +L  D + +VL  V KPPA  V  +I++  + + KP V  F+G   A      V+
Sbjct: 243 EMASRLLLEDHEVQVLVIVGKPPAPEVEERILHLARGSSKPVVLGFVGG-KAKGDQHPVY 301

Query: 301 FASSLDEA-----------------ARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLA 343
               L+E                  A +   +  + A    I P   G++ GLY+GGTL 
Sbjct: 302 ICRELEETAAVAAALAKGEDVPQVRAAMDAQVEELKALAKRIGP-RKGYLRGLYSGGTLC 360

Query: 344 AEAAGLLAGHLGVEADDTH-----QHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRN 398
            EA  +    LG    +T      +    L +  H I+D G+D +T GR HPMID +LR 
Sbjct: 361 YEAQLIARDILGPIHSNTPLEEHLKLEDSLRSVEHTIVDFGEDEFTQGRLHPMIDVSLRA 420

Query: 399 QLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTE 458
               +    P+V V+L DVVIG+G   DPA  LV   +KA         +  +A+V GT 
Sbjct: 421 SRFQEEVKDPEVGVVLFDVVIGYGCHPDPATGLVEGIRKAKEIC--GDRVVFVASVCGTP 478

Query: 459 RDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
            D Q   +Q   LE+AG+ V+ S  +A+ LA+ L+
Sbjct: 479 DDVQDADRQRRILEEAGVVVMDSNAKASRLASFLL 513


>UniRef50_D0WIW7 Protein FdrA n=1 Tax=Slackia exigua ATCC 700122 RepID=D0WIW7_9ACTN
          Length = 488

 Score =  521 bits (1341), Expect = e-146,   Method: Composition-based stats.
 Identities = 193/495 (38%), Positives = 265/495 (53%), Gaps = 22/495 (4%)

Query: 18  MIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGI 77
           M IS+KL++  ++  VSV MGT  NK +L   GF      +A PND+ +A   E  D+  
Sbjct: 1   MGISKKLNDLPDILSVSVSMGTDMNKQILIDGGFDASSIGDAGPNDLMIACSFE--DSVR 58

Query: 78  AQAIMQQLEEALKQL-AQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQ 136
            + ++  LE ALK+   Q    S+   + R    A + + DAN+A+ISV G YAA  A +
Sbjct: 59  EEDVLADLEAALKKQVTQKDRDSE---RPRTLTRAAEDV-DANIAVISVPGIYAAAEARK 114

Query: 137 ALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNI 196
           AL++ L+V+MFSDNV+L+DEI LK  A  KGLL+MGPDCGT    G    FAN +  G+I
Sbjct: 115 ALEKGLHVLMFSDNVSLDDEIALKDLAHGKGLLMMGPDCGTCAFQGVAFCFANAVQRGSI 174

Query: 197 GVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVL 256
           G++ ASGTG QE    +   G G++  IG GGRDLS EVGG   L A + L ADE +  +
Sbjct: 175 GIVSASGTGAQEAAVLLDSWGMGVSQIIGTGGRDLSIEVGGRMFLDAFDALEADEGTSHI 234

Query: 257 AFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLL- 315
             +SKPP E V  K+ +    + KP VA FLG        E V F S +  A     LL 
Sbjct: 235 LLISKPPHETVARKVRDRAARSTKPVVACFLGDVAEDL-SETVLFKSDIVSAVDALALLV 293

Query: 316 -SRVTARRNAIAP----VSSGFICGLYTGGTLAAEAAGLLAGHL---GVEADDTHQHGMM 367
            S  +A   +           ++ GL+ GGTL  EA       L    V A+      + 
Sbjct: 294 DSSFSAPEESAIEIDCMPDGSYVRGLFCGGTLMEEAKMTFMSSLPDVDVYANSAKGGSIS 353

Query: 368 LD----ADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGA 423
           LD    +  H  +DLGDD +T G+PHPMIDP  RN  IA   A  +  V+LLD V+G+GA
Sbjct: 354 LDDSSESRGHAFLDLGDDAFTQGKPHPMIDPQTRNARIAQEAADTETAVILLDFVLGYGA 413

Query: 424 TADPAASLVSAWQKACAARLD-NQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSL 482
             DP  + + A  KA  + L+  + +  IA V GT+ DPQ +  Q   L   G+ V  + 
Sbjct: 414 HEDPVGAALPAIHKANVSCLESGRTMVFIAYVLGTDADPQDKQHQEEMLAQEGVLVCQTN 473

Query: 483 PEATLLAAALIHPLS 497
            +A  LAA+++  L 
Sbjct: 474 VQAANLAASIVKGLR 488


>UniRef50_D2L8W4 FdrA family protein n=1 Tax=Desulfovibrio sp. FW1012B
           RepID=D2L8W4_9DELT
          Length = 502

 Score =  487 bits (1254), Expect = e-136,   Method: Composition-based stats.
 Identities = 187/493 (37%), Positives = 275/493 (55%), Gaps = 18/493 (3%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           ++ A ++K  +QDSV LM ISR+ S+   V  V  ++GT +NK +L   G   D    AT
Sbjct: 2   LLQATVRKNQYQDSVRLMQISRQASQLPGVGKVLALLGTDSNKKVLADLGLMDDVVAAAT 61

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
            ND+ + + +E A+A  A            +L   + +  A    +  + A  +L  AN 
Sbjct: 62  ANDLVICVEAENAEAVAAALADVD-----GRLRSVAAAGPAEANPKSLEEAVARLSGANF 116

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           A+IS+ G+ A      AL++ L+VM+FSDN++L DE +LK  A +KGLL+MGPDCGT++I
Sbjct: 117 AMISLPGQLAKLDVVTALEQGLHVMLFSDNISLADEAELKALAAKKGLLLMGPDCGTAII 176

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            G  LA ANV+  G IG+  ASGTGIQE+   I   G G++HAIG+GGRDL +EVGG   
Sbjct: 177 NGVALALANVVRRGEIGLAAASGTGIQEVTCLIDRFGGGVSHAIGVGGRDLKKEVGGTMM 236

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
             A+ +L+AD  ++ L  +SKP A  V   +++  + +G   V   LG   A A  E + 
Sbjct: 237 RQAIRILAADPATKTLVVLSKPGAPEVMETVLDEARQSGLRVVTCLLGGD-ASAAPEGMV 295

Query: 301 FASSLDEAARLACL-----LSRVTARRNAIAPVSSG--FICGLYTGGTLAAEAAGLLAGH 353
             S+L+EAA  A       L+     R   A +SSG  ++ GLY+GGTL  E   LL   
Sbjct: 296 CVSTLEEAAFAALDRDLPPLAIPPGLRERAAALSSGRQYLRGLYSGGTLCYETLFLLKDD 355

Query: 354 LGVEAD----DTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQ 409
           L ++++       + G  +    H  +DLG+D +T GRPHP+ID +LR + +A+  A P 
Sbjct: 356 LDIQSNVAIKPELKLGYPVKGTGHCCVDLGEDEFTQGRPHPIIDLSLRLERLAEEMADPS 415

Query: 410 VRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIA 469
           V+V+LLD+V+G+GA  +PAA L  A   A  AR D  P+  +  V GT+ DPQ    Q  
Sbjct: 416 VKVVLLDLVLGYGAHRNPAAELAEAIAAASQARPDGGPV-VLVHVCGTQADPQDLQAQEK 474

Query: 470 TLEDAGIAVVSSL 482
            L + G  +  + 
Sbjct: 475 LLAEVGAFLFPTN 487


>UniRef50_D1A7Z1 FdrA family protein n=2 Tax=Actinomycetales RepID=D1A7Z1_THECD
          Length = 480

 Score =  454 bits (1169), Expect = e-126,   Method: Composition-based stats.
 Identities = 176/480 (36%), Positives = 243/480 (50%), Gaps = 26/480 (5%)

Query: 4   AFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPND 63
             ++ G ++DSV+L+ +SR+L+  E +    V M T  N  LL   GF   +   A P+D
Sbjct: 5   VEVQSGRYRDSVTLLRVSRELAGREGITAAMVAMATEPNLDLLRRRGFAVPE--GAGPDD 62

Query: 64  ICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKL---PDANL 120
           + VAIR   AD    +   + LE  L      +          R   A  +L   P   L
Sbjct: 63  LVVAIRG--ADEASVREARRVLEGLLADDPAPAARHAPQDDPPRTTGAAARLLAEPAGGL 120

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           AL+SV G YA   A  AL+  LNVM+ S +V L  E+ LK  A  +GL+VMGP CGT++I
Sbjct: 121 ALVSVPGRYAFIEAMDALNAGLNVMVCSGDVPLHQEVALKEAAGRRGLIVMGPGCGTAVI 180

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            G  L FAN +  G + ++ ASGTG Q++   +  AG G+ H +G+GGRDLS EV G S 
Sbjct: 181 GGAGLGFANAVRPGPVSIVAASGTGAQQVMCLLDAAGVGVRHVLGVGGRDLSAEVSGRST 240

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTV-ALFLGYTPAVARDENV 299
           L AL  L  D  +E++A V+ PPA  V   + +A +    P   A+    +P +      
Sbjct: 241 LAALAALDEDPATELIAVVAGPPAPRVADLVHSAARRLDTPVHFAMLAEDSPDLTAATER 300

Query: 300 WFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEAD 359
             ++      R  C  +   A      PV+ G + GL+TGG L AEAA +    LG +  
Sbjct: 301 LLSALGRRVPRWPCWPAARPA-----GPVAPGALRGLFTGGALRAEAALIARRMLGPD-- 353

Query: 360 DTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVI 419
                   L    H++IDLG D    GR HPMIDP  R + +A   A P  RV+LLDV++
Sbjct: 354 --------LACGGHRLIDLGADACARGRAHPMIDPAPRLEHLAAAAADPSCRVVLLDVLL 405

Query: 420 GFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVV 479
           G GA  DPAA L  A + A A R D   L  + ++ GT  DPQ   +Q A L+ AG  V 
Sbjct: 406 GQGADPDPAALLAPAIEAALAGRDD---LRVVVSLCGTPADPQGLGRQAAALQRAGADVF 462


>UniRef50_A1SGR4 FdrA family protein n=1 Tax=Nocardioides sp. JS614
           RepID=A1SGR4_NOCSJ
          Length = 471

 Score =  434 bits (1116), Expect = e-120,   Method: Composition-based stats.
 Identities = 185/496 (37%), Positives = 254/496 (51%), Gaps = 33/496 (6%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
           H  ++ G + DSV+L+ +SR +     V    V M TP N  +L  TG   +    A PN
Sbjct: 8   HVELRPGAYADSVTLLQVSRVVQGLPGVLAAQVAMATPLNVEVL--TGMGFEVPAQAGPN 65

Query: 63  DICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           D+ VA+R EA  A    A +  +++AL+   +    +  +   R   SA ++ PDA +AL
Sbjct: 66  DLVVALRLEA--ADALPAALAGVDQALRDANRRDEGAATIAPPRTTASALRRTPDA-VAL 122

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG 182
           +SV G +A   A  A++   +VM+FSDNV LE E+ LK  A E+G+LVMGPDCGT+++ G
Sbjct: 123 VSVPGAHAFVEAMDAVEAGRDVMVFSDNVPLEQELALKRAAAERGVLVMGPDCGTAVVDG 182

Query: 183 TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALT 242
             L FANV+  G +G++ ASGTG Q+L + +  AG G+T A+G+GGRDLS EV G++   
Sbjct: 183 VGLGFANVVEPGPVGIVAASGTGCQQLLALLDHAGVGVTSALGVGGRDLSAEVRGLATRE 242

Query: 243 ALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFA 302
           AL  L  D   E++  +SKPPA  V  +I     A   P     LG              
Sbjct: 243 ALRRLDEDPGVELIVLISKPPAADVTAEIEAYAAALATPVELALLGPGRPDLTAAAEAVL 302

Query: 303 SSLDEAARLACLLSRVTARRNAIAP-VSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDT 361
                  RL   +         ++P V+ G + GL+ GGTLA+EAA +    LG      
Sbjct: 303 R------RLGREVPAWPVDPPDVSPRVNPGALRGLFVGGTLASEAALVAGELLG------ 350

Query: 362 HQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGF 421
                  +AD H  +D GDD YT GR HPMIDP++R + +A   A P   VLLLDVV+G 
Sbjct: 351 -------EADGHTFVDFGDDEYTTGRAHPMIDPSIRLEHLARAAADPTTGVLLLDVVLGH 403

Query: 422 GATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSS 481
           GA  DPAASL  A        +             T  DPQ R +Q+  L DAG  V  S
Sbjct: 404 GAEPDPAASLAPALAGVAQPVVVAVVG--------TAGDPQGRDRQVRALVDAGAEVHLS 455

Query: 482 LPEATLLAAALIHPLS 497
              AT  A  L+    
Sbjct: 456 NAGATRRAIELLGGTR 471


>UniRef50_D2S3V1 FdrA family protein n=8 Tax=Bacteria RepID=D2S3V1_9ACTO
          Length = 490

 Score =  406 bits (1044), Expect = e-112,   Method: Composition-based stats.
 Identities = 184/497 (37%), Positives = 259/497 (52%), Gaps = 24/497 (4%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
           H  ++ G + DSV LM +SR +S  E V  V V M TP N  L    G        A+P+
Sbjct: 8   HVSLRSGVYADSVRLMQVSRDVSAREGVTAVLVAMATPLNLEL--AAGMGLAPAEGASPD 65

Query: 63  DICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
            + VA+ +   DA  A         A ++ A G   +  L  V     A      A LA+
Sbjct: 66  QLLVAVSAVDDDALAAAVAAVDAALAARERAAGPAQTVPLRTVGAGLGALDGDGPA-LAV 124

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG 182
           +SV G+YA   A  A+    +V++FSD V +E E+ LK  A + G+LVMG DCGT++++G
Sbjct: 125 VSVPGQYAVAEAADAIAAGRSVLVFSDGVPVEHEVALKRAAHDAGVLVMGSDCGTAIVSG 184

Query: 183 TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALT 242
             L FANV+  G +G++ ASGTG Q++   +  AG G++H +G+GGRDLS  VGG++ L 
Sbjct: 185 LALGFANVVRRGPVGLVAASGTGAQQVSCLLDTAGVGVSHVLGVGGRDLSEAVGGLATLD 244

Query: 243 ALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFA 302
           AL +  AD  +E +  VSKPPA AV + +  A      P         PA    E+    
Sbjct: 245 ALALFDADPATERVLLVSKPPAPAVAVAVAEAAAELSVPV-------HPAALSAESPDLT 297

Query: 303 SSLDEAAR-LACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDT 361
           ++++   R +   +    +R  A+       + GL+ GGTLA EA  + A  LG    +T
Sbjct: 298 AAVEALLRDMGVAVPEWPSRPAALGAAPGAVLKGLFAGGTLADEAMLIAAPVLGDVRSNT 357

Query: 362 H-----QHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLD 416
                   G  L A  H ++D GDD  TVGR HPMIDPTLR + +A + A  +  V+L+D
Sbjct: 358 PLRPELDLGTDLVARGHVVVDFGDDALTVGRAHPMIDPTLRLEALARIAASGEPAVVLMD 417

Query: 417 VVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGI 476
           VV+G GA  DP ASLV A + A         L A+  + GTE DPQ  S+Q   L  AG 
Sbjct: 418 VVLGHGADPDPVASLVPALRAAG--------LPAVVALVGTEADPQGWSRQADALAAAGA 469

Query: 477 AVVSSLPEATLLAAALI 493
           AV +S  +AT  A  L+
Sbjct: 470 AVFASNAQATRHALDLL 486


>UniRef50_C7QE97 FdrA family protein n=1 Tax=Catenulispora acidiphila DSM 44928
           RepID=C7QE97_CATAD
          Length = 629

 Score =  335 bits (860), Expect = 2e-90,   Method: Composition-based stats.
 Identities = 125/384 (32%), Positives = 186/384 (48%), Gaps = 23/384 (5%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
           H  +++G + DSV+LM+  R ++    V  V V M T  N ALL   G+      +A P 
Sbjct: 20  HVEVRRGEYHDSVTLMLAGRAVAGVAGVGRVLVAMATELNVALLAELGYA--ALPDAGPG 77

Query: 63  DICVAIRSEAA--DAGIAQAI-------MQQLEEALKQLAQGSGSSQALTQVRRWDSACQ 113
           D+ VA   E    DA  + +        +  L ++L     GS ++       R D    
Sbjct: 78  DLVVAFTCEGDGGDAEGSDSADATESAALAALADSLTPQPGGSITAPGHPHQGRPDQPAP 137

Query: 114 KLP-------DANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREK 166
           +          A + LIS  G  +   A ++L+   + ++FSDN+ +  E++LK  AR +
Sbjct: 138 RTTATALGRTSAPITLISTPGLASVAEAMESLEYGASPIIFSDNIPIHHEVRLKEEARRR 197

Query: 167 GLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGL 226
           GLLVMGPDCGT ++ GT LAFA ++  G I ++ ASGTG Q+L + +  AG GI H +G+
Sbjct: 198 GLLVMGPDCGTVVLHGTGLAFATIVRPGPISLVAASGTGAQQLMALLDAAGTGIHHCLGV 257

Query: 227 GGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALF 286
           GGRDL+ +V G S L AL  L+ D  +E++  VSKPP   +  KI       GKP    F
Sbjct: 258 GGRDLTEQVAGRSTLAALTALADDPATELITVVSKPPHPTIAAKIQAHAATLGKPVHFAF 317

Query: 287 LGYTPAVARDENVWFASSLDEAA-----RLACLLSRVTARRNAIAPVSSGFICGLYTGGT 341
           +G       +      ++L   A     + A   +          P S+  I GL++GGT
Sbjct: 318 VGPNHPTLTESAEHILTALGHQAPQPWPQWAPTATTAAVATTEPMPPSAPMIRGLFSGGT 377

Query: 342 LAAEAAGLLAGHLGVEADDTHQHG 365
           L AEA  +L    G   D+    G
Sbjct: 378 LRAEAEVVLTRAGGQMIDNQRSGG 401



 Score = 99.7 bits (247), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 47/108 (43%), Positives = 61/108 (56%), Gaps = 3/108 (2%)

Query: 375 IIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSA 434
           + D GDD YT GRPHPMID TLR++ +A+  A  +V V+LLDVV+G GA ADP A + +A
Sbjct: 500 LTDFGDDAYTRGRPHPMIDNTLRSRGVAEAAADERVGVVLLDVVLGRGAHADPGAEIAAA 559

Query: 435 WQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSL 482
              A   R     L  + ++ G   DPQ   +Q   L  AG  V  S 
Sbjct: 560 IGAARGVRAG---LAVVVSLCGAAGDPQGLGRQAGVLAGAGAWVFLSN 604


>UniRef50_A3DLS0 Succinyl-CoA synthetase (ADP-forming) alpha subunit n=7
           Tax=cellular organisms RepID=A3DLS0_STAMF
          Length = 293

 Score =  185 bits (470), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 46/213 (21%), Positives = 101/213 (47%), Gaps = 12/213 (5%)

Query: 94  QGSGSSQALTQVRRWDS---ACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSD 149
                   +  V  +D+   A + + + + ++I V  ++A++   +A+D ++  +++ ++
Sbjct: 40  TPGKGGMNVYGVPVYDTIYEAVENIGEIDASIIFVPAKFASDAVFEAIDADIKTIVVITE 99

Query: 150 NVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTGI 206
            + + +E++    A++K + ++GP+    M+ G     +  A+V   GNIG+I  SGT  
Sbjct: 100 GIPVHEELEFVRYAKKKNITIIGPNTPGIMVPGETKIGIMPAHVFKPGNIGLISRSGTLT 159

Query: 207 QELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAE- 265
            E+  +I   G GI+  IGLGG  ++    G++ + A ++ + D  ++ +  + +   + 
Sbjct: 160 YEIAREIGKKGYGISTVIGLGGDPVT----GLNFIEAYDLFAKDPITKAVVLIGEIGGDA 215

Query: 266 AVRLKIVNAMKATGKPTVALFLGYTPAVARDEN 298
             R     A     KP VA   G T    +   
Sbjct: 216 EERFAKYYAELPVKKPVVAYIAGKTAPPGKRMG 248


>UniRef50_P53595 Malate--CoA ligase subunit alpha n=184 Tax=cellular organisms
           RepID=MTKB_METEA
          Length = 296

 Score =  174 bits (441), Expect = 7e-42,   Method: Composition-based stats.
 Identities = 51/232 (21%), Positives = 95/232 (40%), Gaps = 17/232 (7%)

Query: 94  QGSGSSQALTQVRRWDSACQKL--PDANLALISVAGEYAAELANQALDRNLN-VMMFSDN 150
                 +    V  +++  + +    A  ++  VA  +AA+   +A D  L  V   +D 
Sbjct: 40  TPGKGGKTHCGVPVFNTVKEAVEATGATTSITFVAPPFAADAIMEAADAGLKLVCSITDG 99

Query: 151 VTLEDEIQLKTRAR----EKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASG 203
           +  +D +++K   R    EK  +V+GP+C   +  G     +   ++   G +GVI  SG
Sbjct: 100 IPAQDMMRVKRYLRRYPKEKRTMVVGPNCAGIISPGKSMLGIMPGHIYLPGKVGVISRSG 159

Query: 204 TGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPP 263
           T   E  +Q+   G GI+ ++G+GG  ++    G S L  L +   D ++E +  + +  
Sbjct: 160 TLGYEAAAQMKELGIGISTSVGIGGDPIN----GSSFLDHLALFEQDPETEAVLMIGEIG 215

Query: 264 AEAVRLKIVNAMKATGKPTVALFLGYTPAVAR---DENVWFASSLDEAARLA 312
                       +   KP +    G T    R         +++ D AA  A
Sbjct: 216 GPQEAEASAWIKENFSKPVIGFVAGLTAPKGRRMGHAGAIISATGDSAAEKA 267


>UniRef50_Q58643 Succinyl-CoA ligase [ADP-forming] subunit alpha n=65 Tax=cellular
           organisms RepID=SUCD_METJA
          Length = 294

 Score =  167 bits (424), Expect = 8e-40,   Method: Composition-based stats.
 Identities = 40/211 (18%), Positives = 94/211 (44%), Gaps = 11/211 (5%)

Query: 94  QGSGSSQALTQVRRWDSACQ--KLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDN 150
                 Q +  V  +D+  +  K  DAN ++I V   +A +   +A+D  +  +++ +++
Sbjct: 45  TPGKGGQNVHGVPVFDTVKEAVKETDANASVIFVPAPFAKDAVFEAIDAGIELIVVITEH 104

Query: 151 VTLEDEIQLKTRAREKGLLVMGPDCGTSM---IAGTPLAFANVMPEGNIGVIGASGTGIQ 207
           + + D ++    A + G+ ++GP+        +    +    V+ EG++G++  SGT   
Sbjct: 105 IPVHDTMEFVNYAEDVGVKIIGPNTPGIASPKVGKLGIIPMEVLKEGSVGMVSRSGTLTY 164

Query: 208 ELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAV 267
           E+  QI  AG G++  +G+GG      + G+     L++   D+++E +  + +      
Sbjct: 165 EIAHQIKKAGFGVSTCVGIGGDP----IVGLRYKEVLDLFEKDDETEAIVMIGEI-GGGA 219

Query: 268 RLKIVNAMKATGKPTVALFLGYTPAVARDEN 298
             +    ++   KP +    G +    +   
Sbjct: 220 EEEAAKFIEKMKKPVIGYIAGQSAPEGKRMG 250


>UniRef50_C9KQT1 Succinyl-CoA ligase [ADP-forming] subunit alpha n=1 Tax=Mitsuokella
           multacida DSM 20544 RepID=C9KQT1_9FIRM
          Length = 301

 Score =  167 bits (423), Expect = 9e-40,   Method: Composition-based stats.
 Identities = 46/212 (21%), Positives = 90/212 (42%), Gaps = 11/212 (5%)

Query: 94  QGSGSSQALTQVRRWDSACQKL--PDANLALISVAGEYAAELANQALDRNLNVMM-FSDN 150
                 Q    V  +++  + +    A  ++I V   +AA+   +A+D +L+V++  S++
Sbjct: 40  TPGKGGQIACGVPVFNTVREAVEATGATASVIYVPARFAADSIMEAVDADLDVVVCISEH 99

Query: 151 VTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTGIQ 207
           + ++D I+++     +   ++GP+C   + A      +    +  +G++GVI  SGT   
Sbjct: 100 IPVQDMIKVRRYMEGRKTHLIGPNCPGILTADECKLGIIPGYIHRKGHVGVISRSGTLTY 159

Query: 208 ELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAV 267
           E   Q+  AG G T AIG+GG      V G   + AL++   D ++  +  + +    A 
Sbjct: 160 EATFQLTAAGIGQTTAIGIGGDP----VKGTDFIDALKLFKEDPETLAVLMIGEIGGTAE 215

Query: 268 RLKIVNAMKAT-GKPTVALFLGYTPAVARDEN 298
                        KP  A   G      +   
Sbjct: 216 EDAAKWIAANMPDKPVAAFIAGRQAPPGKRMG 247


>UniRef50_Q3ADM2 Succinyl-CoA ligase [ADP-forming] subunit alpha n=5 Tax=cellular
           organisms RepID=Q3ADM2_CARHZ
          Length = 289

 Score =  167 bits (422), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 40/211 (18%), Positives = 92/211 (43%), Gaps = 11/211 (5%)

Query: 94  QGSGSSQALTQVRRWDSACQKL--PDANLALISVAGEYAAELANQALDRNLN-VMMFSDN 150
                   +  V  +++    +    AN +++ +   +  + A +A++  +  +++ S++
Sbjct: 40  SPGKGGTEVLGVPVFNTVLDAVKNTGANTSILFIPAPFVLDAALEAMEAGIKTIVIISEH 99

Query: 151 VTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTGIQ 207
           V L D +++   A   G+ V+GP+    +  G     +    +  +G +G++  SGT   
Sbjct: 100 VPLHDALKIMRVAEAYGVTVVGPNTFGVISPGIAKVGIMPNTIYQKGPVGIVARSGTLSY 159

Query: 208 ELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAV 267
           ++  ++  AG G +  +GLGG      + G+S    +  L+ DE+++ +  V +    A 
Sbjct: 160 QIAYELTRAGLGQSTVVGLGGD----RIVGLSLAEVILSLARDEETQGIVVVGEIGGTA- 214

Query: 268 RLKIVNAMKATGKPTVALFLGYTPAVARDEN 298
             +    ++   KP VA   G T    +   
Sbjct: 215 EEEAAEVIRHINKPVVAFIAGKTAPPGKRMG 245


>UniRef50_Q2TTV5 Putative uncharacterized protein n=1 Tax=Escherichia coli
           RepID=Q2TTV5_ECOLX
          Length = 192

 Score =  161 bits (408), Expect = 5e-38,   Method: Composition-based stats.
 Identities = 57/152 (37%), Positives = 83/152 (54%), Gaps = 8/152 (5%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           +   +    +QDSVSLM IS ++S+   +   SV+MGTP N   L   G  ++   NA+P
Sbjct: 25  VKYKVFSNLYQDSVSLMQISAQISKLPGIQQASVVMGTPNNLEQLRDAGLGNEI--NASP 82

Query: 62  NDICVAIRSEAADAGIAQAIMQQ--LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDAN 119
           ND+ +A+  E      A  + QQ    +   +   G  S + +      + A +  P+AN
Sbjct: 83  NDLVIAVMGEEDICNEALLLAQQRLTSKPDDETDCGIKSPEKV----SLEMALEAEPEAN 138

Query: 120 LALISVAGEYAAELANQALDRNLNVMMFSDNV 151
           LALISV G+YAA  A +AL+  +NVMMFSDNV
Sbjct: 139 LALISVPGDYAAAEAIKALNLGMNVMMFSDNV 170


>UniRef50_C0BZV5 Putative uncharacterized protein n=2 Tax=Clostridium hylemonae DSM
           15053 RepID=C0BZV5_9CLOT
          Length = 306

 Score =  159 bits (401), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 44/210 (20%), Positives = 87/210 (41%), Gaps = 10/210 (4%)

Query: 92  LAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVM-MFSDN 150
             +G  S + +        A    P+   A++ V  ++  + A QALD  + ++ + ++ 
Sbjct: 41  PGKGGQSVEGVPVFETVADARAVFPEIRAAMLLVPKQFVRDAAFQALDEGIRLLAVITEF 100

Query: 151 VTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTGIQ 207
           V + D +Q+  +A+     V+GP+    +  G     +    +  +G+IG+I  SGT   
Sbjct: 101 VPVMDALQIVHKAKALDAQVVGPNTIGVISPGKSKLGIMPDYIYGKGHIGIISRSGTLTH 160

Query: 208 ELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAE-A 266
           E  S +   G G++  +G+GG      V G+     +E  + D++++ +  + +      
Sbjct: 161 ETASNLTFKGFGLSTCVGIGGD----AVVGMDHADVIEYFAQDDETDAIVIIGEIGGTSE 216

Query: 267 VRLKIVNAMKATGKPTVALFLG-YTPAVAR 295
                        KP  A   G Y P   R
Sbjct: 217 EMAAAKIKELNLKKPVCAYIAGMYAPENKR 246


>UniRef50_Q65SV2 Succinyl-CoA ligase [ADP-forming] subunit alpha n=1 Tax=Mannheimia
           succiniciproducens MBEL55E RepID=Q65SV2_MANSM
          Length = 289

 Score =  158 bits (400), Expect = 5e-37,   Method: Composition-based stats.
 Identities = 37/211 (17%), Positives = 84/211 (39%), Gaps = 10/211 (4%)

Query: 94  QGSGSSQALTQVRRWDSACQKL--PDANLALISVAGEYAAELANQALDRNLNVMM-FSDN 150
                      +  +++  + +    A   +I V   +  +   +A+   L +++  ++ 
Sbjct: 40  SPGKGGSIHLGLPVFNTVKEAVEQTGATATVIYVPAPFCKDAILEAIAAGLKLIVCITEG 99

Query: 151 VTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTGIQ 207
           +   D +Q+K +  E G++++GP+C   ++       +    +  +G +G++  SGT   
Sbjct: 100 IPTLDMLQVKQKLDESGVVMIGPNCPGIIVPDECKIGIMPGYIHKKGRVGIVSRSGTLTY 159

Query: 208 ELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAV 267
           E   Q    G G +  +G+GG      + G + +  L++  AD K+E +  + +    A 
Sbjct: 160 EAVKQTTDEGFGQSACVGIGGDP----IPGSNFIDILKLYQADPKTEAIVMIGEIGGSAE 215

Query: 268 RLKIVNAMKATGKPTVALFLGYTPAVARDEN 298
                       KP V+   G T    +   
Sbjct: 216 EEAAEFIKAHVTKPVVSYIAGITAPKGKRMG 246


>UniRef50_C0XJA3 Putative uncharacterized protein (Fragment) n=1 Tax=Lactobacillus
           hilgardii ATCC 8290 RepID=C0XJA3_LACHI
          Length = 145

 Score =  156 bits (395), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 58/147 (39%), Positives = 92/147 (62%), Gaps = 3/147 (2%)

Query: 18  MIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGI 77
           M++++ +S    V +V VMMGT ANK +    G   D+  +A PND+ + + ++  D  +
Sbjct: 1   MLLTKNISSMPGVKEVQVMMGTDANKDIFGEAGLLTDEAKSAEPNDMMIVLDADKKD--V 58

Query: 78  AQAIMQQLEEALKQLAQGSGSSQALTQVRR-WDSACQKLPDANLALISVAGEYAAELANQ 136
              +++Q+++ L  L+  S  S + ++    WD A + +PDANLA+ISV G YAA+  + 
Sbjct: 59  MDDVLKQIDKFLNDLSVKSDDSDSDSKKVTNWDDAMKSIPDANLAVISVPGLYAADEIDN 118

Query: 137 ALDRNLNVMMFSDNVTLEDEIQLKTRA 163
           ALD NLN  +FSDNV+LEDE +LK +A
Sbjct: 119 ALDHNLNAFVFSDNVSLEDESRLKKKA 145


>UniRef50_B5I859 Succinyl-CoA ligase [ADP-forming] subunit alpha n=3
           Tax=Actinomycetales RepID=B5I859_9ACTO
          Length = 309

 Score =  153 bits (386), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 40/216 (18%), Positives = 87/216 (40%), Gaps = 12/216 (5%)

Query: 89  LKQLAQGSGSSQALTQVRRWDSACQKL--PDANLALISVAGEYAAELANQALDRNLNV-M 145
           +     G         V  + S    +    A++ ++ V   +A     +A+D  + + +
Sbjct: 39  VNPRKAGQRVDFDDRAVPVFGSVADGIGATGADVTVVFVPPPFAGAAVVEAVDAGIALAV 98

Query: 146 MFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGAS 202
           + ++ + + D +   + A++KG  ++GP+C   +  G     +  A++   G IG++  S
Sbjct: 99  VITEGIPVHDSVAFTSYAKKKGTRIVGPNCPGLITPGQSNAGIIPADITRSGRIGLVSKS 158

Query: 203 GTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKP 262
           GT   +L  ++   G   +  +G+GG      V G + +  L     D  +E++  + + 
Sbjct: 159 GTLTYQLMYELRDIGF--STCVGIGGDP----VVGTTHIDCLAAFQDDPDTELIVLIGEI 212

Query: 263 PAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDEN 298
             +A         +   KP V    G+T    R   
Sbjct: 213 GGDAEERAAAYIREHVTKPVVGYIAGFTAPEGRTMG 248


>UniRef50_UPI00016B24F6 succinyl-CoA synthetase, alpha subunit n=2 Tax=candidate division
           TM7 RepID=UPI00016B24F6
          Length = 286

 Score =  152 bits (385), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 43/244 (17%), Positives = 98/244 (40%), Gaps = 13/244 (5%)

Query: 88  ALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMM- 146
           A     Q       +   R  D   ++    ++++I V   +A     +A+   + +++ 
Sbjct: 37  AGTSPNQAISEVHGVPVFRTIDDIKKRF-AIDISVIFVPAPHAKAAILEAIQAQIPLIIC 95

Query: 147 FSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASG 203
            ++ V + D +++K +      +++GP+C   ++ G     +  A++   G+  ++  SG
Sbjct: 96  ITEGVPVHDMLEIKQKLHRSRSVLIGPNCPGVLLPGRQLLGIIPASLAVPGDTAIVSRSG 155

Query: 204 TGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPP 263
           T   E  S +  AG G  + IG+GG  +S    G S +  L++   D   + +  + +  
Sbjct: 156 TLTYEAMSLLTQAGFGQRYIIGIGGDMIS----GSSFVDCLQLFQNDPSVKRIVMIGEIG 211

Query: 264 AEAVRLKIVNAMKATGKPTVALFLGYTPA----VARDENVWFASSLDEAARLACLLSRVT 319
             +         ++  KP  A   G++      +     +   ++L+ AA     L +  
Sbjct: 212 GISEITAADYIKQSINKPVYAYIAGHSAPAGIQMGHTGAILGTNALESAATKTAYLQQAG 271

Query: 320 ARRN 323
           A   
Sbjct: 272 AITA 275


>UniRef50_B8DUE3 Succinyl-CoA ligase [ADP-forming] subunit alpha n=25 Tax=Bacteria
           RepID=B8DUE3_BIFA0
          Length = 305

 Score =  136 bits (343), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 54/282 (19%), Positives = 107/282 (37%), Gaps = 31/282 (10%)

Query: 87  EALKQLAQGSGSSQALT-QVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVM 145
           +A   L    G+   +   V       + +  A  +++ V   +A +   +A++    V+
Sbjct: 43  KAGTTLEFEDGNGVPVRVPVFATCQEAKDITGAKASVVFVPPRFAKDAVVEAVEAGFEVV 102

Query: 146 M-FSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI-------AGTPLAFA--NVMPEGN 195
           +  ++ + + D       A  KG+ ++GP+C   +         G  L      ++  G 
Sbjct: 103 VVITEGIPVADSAYFVELALSKGVRIVGPNCPGLLTLPESTDTHGVNLGIIPDGIVSRGP 162

Query: 196 IGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEV 255
           +G++  SGT   +L  +++  G   T  +G GG      + G + L ALE   AD  ++ 
Sbjct: 163 LGLVSKSGTLTYQLMGELSDIGF--TACLGAGGDP----IVGTTLLEALEAFEADPNTKA 216

Query: 256 LAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLL 315
           +  + +    A +     A K   KP VA   G+T    +                A + 
Sbjct: 217 VMMIGEIGGNAEQDAAQWAAKNMTKPVVAYIAGFTAPEGKQMGHAG----------AIVS 266

Query: 316 SRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVE 357
                 ++  A + +  I     G T  +EAA ++   L  +
Sbjct: 267 GGKGTAQDKQAALEAAGIR---VGRT-PSEAAQIMREVLSAQ 304


>UniRef50_P71558 Succinyl-CoA ligase [ADP-forming] subunit alpha n=119 Tax=cellular
           organisms RepID=SUCD_MYCTU
          Length = 303

 Score =  136 bits (343), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 45/225 (20%), Positives = 90/225 (40%), Gaps = 16/225 (7%)

Query: 101 ALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMM-FSDNVTLEDEIQL 159
            L        A +K   A++++I V   +A +   +A+D  + +++  ++ + ++D    
Sbjct: 62  KLPVFGSVAEAMEK-TGADVSIIFVPPTFAKDAIIEAIDAEIPLLVVITEGIPVQDTAYA 120

Query: 160 KTRAREKG--LLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTGIQELCSQIA 214
                E G    ++GP+C   +  G     +  AN+   G IG++  SGT   ++  ++ 
Sbjct: 121 WAYNLEAGHKTRIIGPNCPGIISPGQSLAGITPANITGPGPIGLVSKSGTLTYQMMFELR 180

Query: 215 LAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNA 274
             G   + AIG+GG      V G + + A+E    D  ++++  + +   +A        
Sbjct: 181 DLGF--STAIGIGGDP----VIGTTHIDAIEAFERDPDTKLIVMIGEIGGDAEERAADFI 234

Query: 275 MKATGKPTVALFLGYTPAVAR---DENVWFASSLDEAARLACLLS 316
                KP V    G+T    +         + S   AA     L 
Sbjct: 235 KTNVSKPVVGYVAGFTAPEGKTMGHAGAIVSGSSGTAAAKQEALE 279


>UniRef50_B4UDP3 Succinyl-CoA ligase [ADP-forming] subunit alpha n=10 Tax=cellular
           organisms RepID=B4UDP3_ANASK
          Length = 341

 Score =  135 bits (341), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 42/213 (19%), Positives = 86/213 (40%), Gaps = 9/213 (4%)

Query: 91  QLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMM-FSD 149
              +G    Q    +    +A  K   AN A I V   +AA+   +A + ++ +++  ++
Sbjct: 40  TPNRGGTRFQGTVPIFHTVAAAVKETGANAAAIFVPPPFAADAIIEAAESDIELIVAITE 99

Query: 150 NVTLEDEIQLKTRAREK-GLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTG 205
            + + D ++++     +    ++GP+C   +  G     +   +V   G IGV+  SGT 
Sbjct: 100 GIPVLDMVRVRRYVESRPKTRLVGPNCPGVITPGQCKIGIMPGHVHRPGRIGVVSRSGTL 159

Query: 206 IQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAE 265
             E   Q++  G G + ++G+GG      V G   + AL++   D +++ +  + +    
Sbjct: 160 NYEAVKQLSDLGLGQSTSVGIGGDP----VHGTDFVQALQLFEDDPETDAVIMIGEIGGG 215

Query: 266 AVRLKIVNAMKATGKPTVALFLGYTPAVARDEN 298
                         KP V    G T    +   
Sbjct: 216 EEEKGAEFVRDHMTKPVVGFIAGRTAPPGKRMG 248


>UniRef50_B2J366 CoA-binding domain protein n=7 Tax=Cyanobacteria RepID=B2J366_NOSP7
          Length = 295

 Score =  133 bits (335), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 48/243 (19%), Positives = 98/243 (40%), Gaps = 13/243 (5%)

Query: 98  SSQALTQVRRWD---SACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTL 153
             Q L  +  +D      ++    +  +I V      + A +A+  +++ +++ +  V  
Sbjct: 42  GGQELHGLPVFDLVEEVIEQFGVIDTTIICVDPYDVLDAALEAIASHISQIIIITAGVPP 101

Query: 154 EDEIQLKTRAREKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTGIQELC 210
            D +QL  +A     LV+GP+    ++ G        +     G +G++  S T   E+ 
Sbjct: 102 LDMVQLLRKAEACETLVIGPNSPGIIVPGKILLGTQPSEFYTPGVVGIVSRSSTLTYEVA 161

Query: 211 SQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK 270
            ++  AG G + ++ +G    S  + G S L  L++L  DE +E +  V +P   +    
Sbjct: 162 YELTKAGLGQSISVSIG----SDAIVGSSFLQWLQILDEDETTEAIVLVGQPGGGSEEAA 217

Query: 271 IVNAMKATGKPTVALFLGYTPAVARD--ENVWFASSLDEAARLACLLSRVTARRNAIAPV 328
                +A  KP +A   G      +   +    A+ +          S++ A + A  PV
Sbjct: 218 ARYIAEAIDKPVIAYIAGRQAPPGKSWRQTGTLATVIGRDPNFGTAQSKLAALKEAEVPV 277

Query: 329 SSG 331
           +  
Sbjct: 278 AER 280


>UniRef50_B5W071 CoA-binding domain protein n=5 Tax=Cyanobacteria RepID=B5W071_SPIMA
          Length = 301

 Score =  129 bits (324), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 46/247 (18%), Positives = 98/247 (39%), Gaps = 14/247 (5%)

Query: 58  NATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGS--SQALTQVRRWD---SAC 112
           N TP+   + I+         +A +     +   +A  S       + ++  +D    A 
Sbjct: 2   NLTPDSKVI-IQGLRDSEPSLKAALNMKAYSTNIVACVSAGRGGDIIHEIPFFDLVEQAQ 60

Query: 113 QKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQLKTRAREKGLLVM 171
             +   + ++I V      + A +A+D  +  +++ ++ +   D ++L  +A     LV+
Sbjct: 61  AAVGPVDTSVILVHPYDVLDAALEAIDAGIRQLVIVTEGMPPLDMVRLVRKAEATETLVV 120

Query: 172 GPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
           GP+C   ++ G              G+IG+I  S T   E+   +  A  G + ++ +G 
Sbjct: 121 GPNCPGIIVPGKLLLGTHPPQFYTPGSIGLISRSSTLTYEVAQALTDAKLGQSISVCIG- 179

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG 288
              S  + G S +  L++L  D+ ++ +  V +    +         +   KP VA   G
Sbjct: 180 ---SDLIVGSSFIQWLQILDEDDHTDAIVLVGEVGGSSEEEAASYIAETIDKPVVAYITG 236

Query: 289 YTPAVAR 295
                A+
Sbjct: 237 LHTPKAQ 243


>UniRef50_Q72A60 Succinyl-CoA ligase [ADP-forming] subunit alpha n=12 Tax=cellular
           organisms RepID=Q72A60_DESVH
          Length = 709

 Score =  129 bits (323), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 45/219 (20%), Positives = 87/219 (39%), Gaps = 12/219 (5%)

Query: 97  GSSQALTQVRRWDSACQ--KLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTL 153
              Q    V  +DS  +  +  D +  ++ V   +AA+   +A+   +   +  ++ +  
Sbjct: 462 KGGQVTQGVPVYDSVHEACRQHDIDATILFVPAAFAADSLLEAVAEGIPWAVCITEGIPQ 521

Query: 154 EDEIQLKTRAREKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTGIQELC 210
           +D ++    AR     ++GP+    ++ G     +   NV   G + V   SGT   E  
Sbjct: 522 KDMLRALRVARGARTRIIGPNTPGIIVPGACKVGIMPGNVFSPGPLAVFSRSGTLTYEAA 581

Query: 211 SQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRL- 269
           ++++ AG G +   G+GG        G   ++  E++  DE ++ +  + +    A    
Sbjct: 582 ARLSAAGIGQSLCAGVGGDPYI----GSDFVSLCELVRDDEATQGVLVLGEVGGTAEEEL 637

Query: 270 KIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEA 308
                  A  KP V+   G T    R       + LDEA
Sbjct: 638 AAWVRETAFPKPVVSFVAGRTAPPGRRLG-HAGAILDEA 675


>UniRef50_P53597 Succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial
           n=1187 Tax=root RepID=SUCA_HUMAN
          Length = 346

 Score =  125 bits (313), Expect = 5e-27,   Method: Composition-based stats.
 Identities = 42/218 (19%), Positives = 88/218 (40%), Gaps = 15/218 (6%)

Query: 92  LAQGSGSSQALTQVRRWDSACQK--LPDANLALISVAGEYAAELANQALDRNLN-VMMFS 148
                   Q    +  +++  +      A  ++I V   +AA   N+A++  +  V+  +
Sbjct: 85  GTTPGKGGQTHLGLPVFNTVKEAKEQTGATASVIYVPPPFAAAAINEAIEAEIPLVVCIT 144

Query: 149 DNVTLEDEIQLKTRA-REKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGT 204
           + +  +D +++K +  R++   ++GP+C   +  G     +   ++  +G IG++  SGT
Sbjct: 145 EGIPQQDMVRVKHKLLRQEKTRLIGPNCPGVINPGECKIGIMPGHIHKKGRIGIVSRSGT 204

Query: 205 GIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPP- 263
              E   Q    G G +  +G+GG   +    G   +  LE+   D  +E +  + +   
Sbjct: 205 LTYEAVHQTTQVGLGQSLCVGIGGDPFN----GTDFIDCLEIFLNDSATEGIILIGEIGG 260

Query: 264 -AEAVRLKIVNA--MKATGKPTVALFLGYTPAVARDEN 298
            AE    + +         KP V+   G T    R   
Sbjct: 261 NAEENAAEFLKQHNSGPNSKPVVSFIAGLTAPPGRRMG 298


>UniRef50_B4QTC9 GD20111 n=1 Tax=Drosophila simulans RepID=B4QTC9_DROSI
          Length = 421

 Score =  124 bits (312), Expect = 7e-27,   Method: Composition-based stats.
 Identities = 54/272 (19%), Positives = 95/272 (34%), Gaps = 28/272 (10%)

Query: 91  QLAQGSGSSQALTQVRRWDSACQK-LPDANLALISVAGEYAAELANQALDRNLNVMM-FS 148
              +G          +    A +K  PDA   +I +    AAE    A++  + +++  +
Sbjct: 149 NPKKGGTEHLGKPVFKSVAEAVEKAKPDA--TVIFIPPPSAAEGICAAIESEIGLIVAIT 206

Query: 149 DNVTLEDEIQLKTRA--REKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASG 203
           + +   D +++      +EK  L+ GP+C   +        +   ++   G +G++  SG
Sbjct: 207 EGIPQSDMVRISQMLNCQEKSRLL-GPNCPGIISPDQCKIGIMPGDIHKRGVVGIVSRSG 265

Query: 204 TGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPP 263
           T   E   Q    G G    +GLGG   +    G S + AL++  +D++ + +  + +  
Sbjct: 266 TLTYESVHQTTNVGLGQALCVGLGGDPFN----GTSFIDALKVFLSDKEIKGIVMIGEIG 321

Query: 264 AEAVRLK---IVNAMKAT-GKPTVALFLGYTPAVARDENVWFA--SSLDEAARLACLLSR 317
             A       +         KP V    G T    R      A  S    AA+       
Sbjct: 322 GSAEEDAADFLKEKNTGCEAKPVVGFIAGQTAPPGRRMGHAGAIISGGKGAAKDKVAALE 381

Query: 318 VTARRNAIAPVSSGFICGLYTGGTLAAEAAGL 349
               R    P           G TL  E   L
Sbjct: 382 KAGVRMTANPCH--------LGSTLLEEMIRL 405


>UniRef50_C0CN70 Putative uncharacterized protein n=1 Tax=Blautia hydrogenotrophica
           DSM 10507 RepID=C0CN70_9FIRM
          Length = 289

 Score =  124 bits (310), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 43/241 (17%), Positives = 94/241 (39%), Gaps = 12/241 (4%)

Query: 64  ICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWD--SACQKLPDANLA 121
           +  AI  ++    +   +M      +          Q +  V  +D  S  +K  D +  
Sbjct: 12  LVQAITGKS--GSLQTKVMLDAGTKIVAGVTPGKGGQEVHGVPVYDYISEAKKEHDFDTV 69

Query: 122 LISVAGEYAAELANQALDRNLNVMMFS-DNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           +  V    A +   +A+D  + +++ + + + L+D +++   A+  G  ++GP C   + 
Sbjct: 70  ISFVPPAAAKDSCFEAIDAGIRLLVLTTEEIALQDVVEIIAYAKAHGTTLVGPGCAGVIA 129

Query: 181 AGTPLAFANVMP---EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGG 237
            GT    A+ +     G +GV+  SG    E+   +   G G +  + +GG      + G
Sbjct: 130 PGTCKVGAHPVRFFCPGQVGVVSKSGALSYEIGKTLTDNGIGQSGVVAIGGGP----IWG 185

Query: 238 ISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDE 297
            +   A+E+   D  ++V+  + +    +             KP V+L +G      +  
Sbjct: 186 FTQRDAIELYEEDPDTKVIVLLGEIGGGSEEEAAAYIKAHVTKPVVSLIVGRNAPQGKSL 245

Query: 298 N 298
            
Sbjct: 246 G 246


>UniRef50_A9A4P2 CoA-binding domain protein n=9 Tax=Archaea RepID=A9A4P2_NITMS
          Length = 305

 Score =  123 bits (309), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 48/213 (22%), Positives = 93/213 (43%), Gaps = 15/213 (7%)

Query: 95  GSGSSQALTQVRRWDSACQKL--PDANLALISVAGEYAAELANQALDRNLNVMM-FSDNV 151
           G G  +   +V  ++S  + +   +A ++++ V  ++    A  AL+  + +++   ++V
Sbjct: 53  GKGGQKFDDKVPIYNSMQEAVDATNAKISIVFVPAKFFLSAAKDALEAGIKLLVAIPEHV 112

Query: 152 TLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPE-----GNIGVIGASGTGI 206
            + D ++    A++KG +V+GP+    MI    L    +MP      G I V+  SGT +
Sbjct: 113 PVRDTMETLELAKQKGAVVIGPNTPGIMI--PELIKIGIMPPMPFKAGKIAVLSKSGTLL 170

Query: 207 QELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEA 266
            E+   +  AG G +  IG+GG      V G   + A +M+      E +  V +   ++
Sbjct: 171 YEISDALTNAGFGQSITIGIGGDP----VNGTRLIDAFDMVKDIPDLEGMVVVGEIGGDS 226

Query: 267 VRLKIVNAM-KATGKPTVALFLGYTPAVARDEN 298
             +     +     KPTVA   G      +   
Sbjct: 227 EEMLAQRIIDSGFNKPTVAYIAGRAAPKEKRMG 259


>UniRef50_Q1IZE6 Succinyl-CoA ligase [ADP-forming] subunit alpha n=107 Tax=cellular
           organisms RepID=Q1IZE6_DEIGD
          Length = 303

 Score =  122 bits (307), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 40/253 (15%), Positives = 88/253 (34%), Gaps = 25/253 (9%)

Query: 65  CVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPD--ANLAL 122
            + +     +       M++    +          Q    V  ++S  +   +   + ++
Sbjct: 11  VLVVGITGREGSNHTRAMKEFGTQIVAGVTPGKGGQTHEGVPVYNSVKEAQAEHRIDTSI 70

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQLKTRAREK----------GLLVM 171
           I V    AA+   ++    +  +++ ++ V   D ++     +            G+ ++
Sbjct: 71  IFVPPAGAADAVLESAHAGVPLIVLITEGVPTVDMMKAVQEVKALDRANRAEGGPGIRLI 130

Query: 172 GPDCGTSMIAGTPLAFANVMP------EGNIGVIGASGTGIQELCSQIALAGEGITHAIG 225
           G +C   + +G       +MP      +G +G+I  SGT   E    +  AG G +  +G
Sbjct: 131 GGNCPGLVTSGE--CKVGIMPNRIYEQKGRVGLISRSGTLTYEAAKLLLDAGLGTSTTVG 188

Query: 226 LGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVAL 285
           +GG      V G +    L M  AD +++ +  + +                  KP VA 
Sbjct: 189 IGGDP----VIGTTFADVLPMFEADPETDAVVVIGEIGGADEEAAAEYIAANMKKPVVAF 244

Query: 286 FLGYTPAVARDEN 298
             G +    +   
Sbjct: 245 ISGRSAPKGKRMG 257


>UniRef50_D2RT64 Succinyl-CoA synthetase, alpha subunit n=14 Tax=cellular organisms
           RepID=D2RT64_9EURY
          Length = 290

 Score =  122 bits (305), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 46/243 (18%), Positives = 96/243 (39%), Gaps = 12/243 (4%)

Query: 92  LAQGSGSSQALTQVRRWDSACQKLPD--ANLALISVAGEYAAELANQALDRNLNVMM-FS 148
            A      Q +  V  +D+  + + +  A+ ++I V   +A +   ++LD +L++ +  +
Sbjct: 38  GAVPGKGGQEVEGVPVYDTVHEAVEEENADTSVIFVPPAFAGDAVFESLDADLDLAVAIT 97

Query: 149 DNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTG 205
           + +  +D  ++  R  E    ++GP+C   +  G     +   N+  EGN+G++  SGT 
Sbjct: 98  EGIPTQDMARVNKRLTETDTRLIGPNCPGLITPGEAKLGILPGNIFAEGNVGLVSRSGTL 157

Query: 206 IQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAE 265
             ++   +   G G T AI          + G   + ALE+   D  ++ +    +   E
Sbjct: 158 TYQVVDSLTNRGIGQTTAI----GIGGDPIIGTDFVDALELFEDDPDTDAIVMCGEIGGE 213

Query: 266 AVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAI 325
                          P      G T    +      A ++   +      S+++A  +A 
Sbjct: 214 DEEEAAAFIDDYVDTPVAGFIAGRTAPPGKRMG--HAGAIVSGSGTGTAESKISALNDAG 271

Query: 326 APV 328
            PV
Sbjct: 272 VPV 274


>UniRef50_B1Y9G0 Succinyl-CoA synthetase, alpha subunit n=4 Tax=cellular organisms
           RepID=B1Y9G0_THENV
          Length = 292

 Score =  120 bits (302), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 47/215 (21%), Positives = 88/215 (40%), Gaps = 15/215 (6%)

Query: 94  QGSGSSQALTQVRRWDSACQKLP--DANLALISVAGEYAAELANQALDRNLN-VMMFSDN 150
                  ++  V  +D+  + +    AN ++I V    AAE   +A+D  +  V++ +++
Sbjct: 40  TPGKGGASVHGVPVYDTVEEAVRRHGANASVIFVPARAAAEAVLEAVDAGVELVVVITEH 99

Query: 151 VTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMP------EGNIGVIGASGT 204
           + + D ++    AR +G+ V+GP+C   +          +MP       G + V+  SGT
Sbjct: 100 IPVHDALRAINYARSRGVTVIGPNCPGVVAPPVR-TKLGIMPNSIYQTPGKVAVVSRSGT 158

Query: 205 GIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPA 264
              E+  Q+  AG GI     +        V G+  + A   ++ D     +  + +   
Sbjct: 159 LTYEISYQLVRAGFGIN----IAVGVGGDPVVGLDLMEATLKVAEDPDVRGIVVIGEVGG 214

Query: 265 E-AVRLKIVNAMKATGKPTVALFLGYTPAVARDEN 298
           +   RL  + A  A  KP VA   G T    +   
Sbjct: 215 DAEERLAKLYAEGAINKPVVAYIAGRTAPPGKRMG 249


>UniRef50_A7HMU3 CoA-binding domain protein n=3 Tax=Thermotogaceae
           RepID=A7HMU3_FERNB
          Length = 285

 Score =  119 bits (299), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 40/206 (19%), Positives = 83/206 (40%), Gaps = 15/206 (7%)

Query: 101 ALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQL 159
            +           +  + + A+  V   Y  E    A +  +   ++ +++V + D +++
Sbjct: 47  NVPVYNTLSDYVSRGFNVDTAIFFVPAPYVMEAFLDAFNNGVKKFVVITEHVPIHDALRM 106

Query: 160 KTRAREKGLLVMGPDCGTSMIAGTPLAFANVMP-----EGNIGVIGASGTGIQELCSQIA 214
               ++  L ++GP+C   + +   +    +MP     EG + +I  SGT + E+   I 
Sbjct: 107 VDIVKKNNLTMVGPNCPGVIYSKEKV-KLGIMPEKYFKEGEVAIISRSGTLMYEIAKYIG 165

Query: 215 LAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNA 274
               G++  IGLGG      V G++ L A + ++     E +  + +   E     +  A
Sbjct: 166 E-SYGVSIGIGLGGDP----VIGLNVLEAFKEVAK-LGFEKVVLIGEIGGEDEITGVAEA 219

Query: 275 MKATGKP--TVALFLGYTPAVARDEN 298
           +K   KP   V+ F G      +   
Sbjct: 220 IKMGFKPSNIVSFFAGRHAPEGKRMG 245


>UniRef50_Q07LP7 Succinyl-CoA synthetase (ADP-forming) alpha subunit n=5
           Tax=Rhizobiales RepID=Q07LP7_RHOP5
          Length = 306

 Score =  119 bits (299), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 43/215 (20%), Positives = 87/215 (40%), Gaps = 17/215 (7%)

Query: 91  QLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMM-FSD 149
              +   +   +       +A  + P  ++A++ +    A E A  A++    +++  ++
Sbjct: 39  NPKRAGETHLGIPVYASARAAMAETP-FDVAVMFIPPALAEEAALDAIEAGAQLLVVLTE 97

Query: 150 NVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMP--------EGNIGVIGA 201
           ++ + D++ +   AR  G  ++GP+    +  G    FA +MP         G +GV+  
Sbjct: 98  HIPIHDQMVIHAAARRNGTRILGPNTAGLVTPGEG--FAGIMPGHNGSIFQPGVVGVVSR 155

Query: 202 SGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSK 261
           SG+    +   +  AG G +  IG+GG  +     G +   ALE L  D ++  +  V +
Sbjct: 156 SGSLGTLVSLNLTRAGLGQSAFIGIGGDPMI----GTTTRDALEALDRDPRTRAVVLVGE 211

Query: 262 PPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARD 296
               A+  +         KP VA   G      + 
Sbjct: 212 IGG-AMEEEAATYAARMTKPVVAFIAGRASPPGKK 245


>UniRef50_B8FZH7 CoA-binding domain protein n=1 Tax=Desulfitobacterium hafniense
           DCB-2 RepID=B8FZH7_DESHD
          Length = 292

 Score =  117 bits (292), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 44/218 (20%), Positives = 84/218 (38%), Gaps = 17/218 (7%)

Query: 91  QLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFS-D 149
              +       +        A Q+ P    +L+ V  + A     +ALD  + V++ + +
Sbjct: 40  TPGKEGQDVDGIPVYHTVRRAVQEHP-IEASLLVVPPKAAKGAVLEALDSGIKVIVVTAE 98

Query: 150 NVTLEDEIQLKTRAREKGLLVMGPDC------GTSMIAGTPLAFANVMPEGNIGVIGASG 203
            + L + +QL+  A EK  +V+G +       G +M+   P     V   G +GV+  SG
Sbjct: 99  GIPLHEMMQLRKIALEKQAMVIGGNTTGIISTGKAMMGFFPYWLDRVYKPGRVGVMTRSG 158

Query: 204 TGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPP 263
           +   E+ ++I  AG G +  +G+GG  +            L +   D  ++ +  + +  
Sbjct: 159 SLTNEVTAEIVKAGFGPSSIVGVGGDPVPL----TRFAEILPLFEKDPDTDAVVMIGEIG 214

Query: 264 A---EAVRLKIVNAMKATGKPTVALFLGYTPAVARDEN 298
               E V   I   +    KP +    G T    +   
Sbjct: 215 GTMEEDVAEAIEQRI--FTKPLIGFMGGRTAPKGQKMG 250


>UniRef50_A6DYT9 Succinyl-CoA ligase [ADP-forming] subunit alpha n=3
           Tax=Rhodobacteraceae RepID=A6DYT9_9RHOB
          Length = 299

 Score =  115 bits (289), Expect = 4e-24,   Method: Composition-based stats.
 Identities = 44/215 (20%), Positives = 83/215 (38%), Gaps = 14/215 (6%)

Query: 91  QLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMF-SD 149
           +  +G      L        A +    AN +L+ V    A     +A++  ++V++  ++
Sbjct: 40  RPGKGGARHLGLPLFNTVREAVEA-TQANASLVIVPAPQAGPAMIEAIEAGVSVVVCVTE 98

Query: 150 NVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMP-----EGNIGVIGASGT 204
            V   D  ++K        +++GP+    +  G       VMP      G+IG+   S +
Sbjct: 99  RVPQHDMSRVKQALAGTDTILIGPNSQGILTPGQ--CKIGVMPTVNAMPGHIGIASRSAS 156

Query: 205 GIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPA 264
              E+ +Q + AG G +  +G+GG  L     G+  +  L+    D ++E +  + +   
Sbjct: 157 LTSEILAQCSKAGLGQSTTVGIGGDTLH----GVGFVDCLKAFRDDPETEAVVMIGEIGG 212

Query: 265 EAVRLKIVNAMKA-TGKPTVALFLGYTPAVARDEN 298
                          GKP VAL +G      R   
Sbjct: 213 RGEEEAAAYLEAVDYGKPVVALVVGRHAPRGRRMG 247


>UniRef50_B8FRW5 Succinyl-CoA ligase [ADP-forming] subunit alpha n=2
           Tax=Desulfitobacterium hafniense RepID=B8FRW5_DESHD
          Length = 293

 Score =  114 bits (285), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 38/215 (17%), Positives = 83/215 (38%), Gaps = 13/215 (6%)

Query: 91  QLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMF-SD 149
              +G      L        A ++    + +LI V   +    A +A+D  + +++  ++
Sbjct: 40  TPGRGGNQVGGLPVYDTVREAKERHK-IDASLIMVPAPFVLSAAIEAIDAGVPLIVIVTE 98

Query: 150 NVTLEDEIQLKTRAREKGLLVMGPDCGTSM----IAGTPLAFANVMPEGNIGVIGASGTG 205
           ++ ++D +++   A+EKG  ++GP+    +         +    +   G IG+I  SGT 
Sbjct: 99  HIPVKDTMKINALAQEKGCRLLGPNTIGVINCREKVKIGIMPGFLYGSGRIGLISRSGTL 158

Query: 206 IQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAE 265
             E  S +   G G++  I         ++ G   + AL+    D+ +E +  + +    
Sbjct: 159 SHETASNLMFKGLGVSTVI----GIGGDQIIGTDFVDALKDFKEDQDTEAVVMLGEIGGN 214

Query: 266 AVRLKIVNAMKAT--GKPTVALFLGYTPAVARDEN 298
               K    +++   GKP      G      +   
Sbjct: 215 R-EEKAAEYLQSCDYGKPVFCFIAGRNAPPGKKMG 248


>UniRef50_Q0D1A9 Succinyl-CoA ligase alpha-chain, mitochondrial n=9 Tax=cellular
           organisms RepID=Q0D1A9_ASPTN
          Length = 577

 Score =  113 bits (283), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 46/219 (21%), Positives = 85/219 (38%), Gaps = 18/219 (8%)

Query: 92  LAQGSGSSQALTQVRRWDSACQK-LPDANLALISVAGEYAAELANQALDRNLNVMM-FSD 149
                G    L       +A +K  PDA  + I V G   A+   +A++  + +++  ++
Sbjct: 81  KPGVEGEHLGLPVFPSVKAAQEKARPDA--SAIYVPGNQTAQAIEEAVEAEIPLVVAVAE 138

Query: 150 NVTLEDEIQLKTRAR-EKGLLVMGPDCGTSMIAG----TPLAFANVMPEGNIGVIGASGT 204
           +V + D +++ +  + +    ++G +C   + A                G +G++  SGT
Sbjct: 139 HVPIHDMLRIHSMLKTQSKTRLVGANCPGIISAIGKCRIGFQPLPCFAPGKVGIVAKSGT 198

Query: 205 GIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPA 264
              E  +    AG G +  I +GG  L     G + + AL++   D  +E +  V +   
Sbjct: 199 LSYETVASTTRAGLGQSLCISMGGDVL----AGTNFVDALKIFEDDPDTEGMIIVGEIGG 254

Query: 265 EAVRL-----KIVNAMKATGKPTVALFLGYTPAVARDEN 298
            A        K  N   A  KP +AL  G      R   
Sbjct: 255 TAEMDAAEWIKDYNRRTANPKPIMALVGGLYAPSGRIMG 293


>UniRef50_B1XIV2 Succinyl-CoA synthetase, alpha chain n=1 Tax=Synechococcus sp. PCC
           7002 RepID=B1XIV2_SYNP2
          Length = 311

 Score =  113 bits (282), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 36/190 (18%), Positives = 77/190 (40%), Gaps = 8/190 (4%)

Query: 111 ACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQLKTRAREKGLL 169
           A  ++ +   +LI V      + A +A+   +  +++ S  V   D ++L  +A+++ + 
Sbjct: 58  AKAQVGEITTSLIFVEPFEVLDAAFEAIAAGIKQLIIVSAGVPPLDMVRLLCQAQQEEVQ 117

Query: 170 VMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGL 226
           ++GP     +I G      +F N    G + ++    +  QE+   +  AG G ++ + +
Sbjct: 118 ILGPGSSGLVIPGQLWLGTSFVNHFQPGEVALLSRFSSLSQEVAILLNQAGLGQSYVVDV 177

Query: 227 GGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALF 286
           G  DL     G      L  L  D +++ +A + +  ++     I         P V   
Sbjct: 178 GNADLP----GSHFAQWLHYLDQDPQTQAIALLGRYGSQEEIDLIPLIRDQIQTPVVTYL 233

Query: 287 LGYTPAVARD 296
            G    + R 
Sbjct: 234 CGSHAPIQRS 243


>UniRef50_UPI000023DDE4 hypothetical protein FG07898.1 n=1 Tax=Gibberella zeae PH-1
           RepID=UPI000023DDE4
          Length = 320

 Score =  111 bits (278), Expect = 6e-23,   Method: Composition-based stats.
 Identities = 43/249 (17%), Positives = 99/249 (39%), Gaps = 18/249 (7%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMM-FSDNVTLEDE 156
           +   L      + A ++L   +++ + + G  AA+   +A+   + +++  +++V + D 
Sbjct: 36  THLGLPLFGSMEKAAEELNP-DVSAVFIRGSLAADAIIEAIKVEIPLIVSVAEHVPVHDM 94

Query: 157 IQLKTRAR-EKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTGIQELCSQ 212
           +++    R +    ++GP+C   +        +        G +G++  SGT   E    
Sbjct: 95  LRVHEVLRTQSKSRLVGPNCPGIIAPEQCRVGIMPYKQYTRGCVGIVSKSGTLSYEAVGA 154

Query: 213 IALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEA--VRLK 270
            + AG G +  +G+GG      + G S + AL++    ++++ +  + +   EA     +
Sbjct: 155 TSRAGLGQSLVVGMGGD----MIPGTSLVDALKLFFEHDETKGMLVIGEIGGEAELEAAE 210

Query: 271 IVNAMKATG---KPTVALFLGYTPAVAR---DENVWFASSLDEAARLACLLSRVTARRNA 324
           ++   +      KP +A+  G T    R           S+D  A+      +       
Sbjct: 211 LIERYRRNTPKPKPIIAMVAGQTAPEHRIMGHAGAMRRDSVDPTAQEKAAALQNAGAVVV 270

Query: 325 IAPVSSGFI 333
             P   G I
Sbjct: 271 PHPGVMGNI 279


>UniRef50_B4U9Z0 CoA-binding domain protein n=7 Tax=Bacteria RepID=B4U9Z0_HYDS0
          Length = 329

 Score =  110 bits (274), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 37/248 (14%), Positives = 83/248 (33%), Gaps = 20/248 (8%)

Query: 64  ICVAIRSEAADA--GIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
           + + I    A       +A+     +A     +G  S   +        A    P+ N  
Sbjct: 14  VVIGITGREASQVVTETEALYPGFIKAGVTPGKGGASVANVPVYNTVKEAKTHHPEINAG 73

Query: 122 LISVAGEYAAELANQALDRNLNVM-MFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           LI V      +   + ++  + ++ + +++V + D       A+E+G++++GP    +++
Sbjct: 74  LIYVPPVSVKDAVIELVNNGIKLIYIITEHVPIRDTAYFYNYAKERGVIIVGPTSLGAIV 133

Query: 181 AGTPLAFANV--------MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
              P+    +           G + ++  SG         +   G G+  AI LGG  +S
Sbjct: 134 PSVPMRVGAIGGKDPSIAYKPGGLVILSKSGGLTTTTAEMMMRRGWGVYTAIALGGDVIS 193

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPA-----EAVRLKIVNAMKATGKPTVALFL 287
                 +    +  +  D   + +    +         A+ +  +       KP  A   
Sbjct: 194 C----TTFEDVIRNIHNDPNVKAIVIQGEVGGTYEENAAMAILELYKQGKWKKPVAAFVA 249

Query: 288 GYTPAVAR 295
           G       
Sbjct: 250 GRFQENLE 257


>UniRef50_UPI0001C319CC CoA-binding domain protein n=1 Tax=Conexibacter woesei DSM 14684
           RepID=UPI0001C319CC
          Length = 307

 Score =  109 bits (273), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 43/249 (17%), Positives = 90/249 (36%), Gaps = 19/249 (7%)

Query: 56  FNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKL 115
             +AT   I   I    A     + +       +          + +  V  +D+  Q +
Sbjct: 4   LVDATTTFIVQGITGREAVNLTRECLDYGAGARVVGGVTPGRKGREVHGVPVFDTVAQAV 63

Query: 116 ----PDANLALISVAGEYAAELANQALDRNLNVMMF-SDNVTLEDEIQLKTRAREKGLLV 170
                  + ++++V   +  +   +A+   + +++  ++ +   D   +   A   G  +
Sbjct: 64  EHHGAPIDGSVVTVPPAFTKDAVLEAVANGIKLIVIVTERIPRRDVAVMVEFASAHGARI 123

Query: 171 MGPDCGTSM---------IAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGIT 221
           +GP+C   +         I G     A     G +GVI  SG    E+ S +  AG G +
Sbjct: 124 IGPNCLGIIVPDVIKMGGIGGPAKDAAKAYSPGPVGVISRSGGMTTEMSSTLTAAGLGQS 183

Query: 222 HAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKA-TGK 280
            A+ +GG      + G S    + +  ADE+++ +   ++P             +  +  
Sbjct: 184 TAVSIGGD----AIIGSSYAELMPLFEADEQTQAIVIYTEPGGRMEAELAAWVKEHDSRL 239

Query: 281 PTVALFLGY 289
           P VA   G 
Sbjct: 240 PIVAFMAGR 248


>UniRef50_Q2RLF6 Succinyl-CoA synthetase (ADP-forming) alpha subunit n=3
           Tax=Clostridia RepID=Q2RLF6_MOOTA
          Length = 298

 Score =  108 bits (270), Expect = 6e-22,   Method: Composition-based stats.
 Identities = 41/220 (18%), Positives = 77/220 (35%), Gaps = 15/220 (6%)

Query: 88  ALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNL-NVMM 146
           A     +G  +   +        A  +    + ++I V G        +A D  + N++ 
Sbjct: 37  AGTSPGKGGQTVAGIPVYHTVKEAVAEHGPIDFSVIFVPGRALKVAVKEAADAGIKNIVP 96

Query: 147 FSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLA--------FANVM-PEGNIG 197
             ++V + D +++    + KG  ++GP     +  G  +         +AN     G IG
Sbjct: 97  CVESVPIHDIMEMVAYCKMKGTRLIGPGSIGIITPGEAVVGWLGGNVEWANTFFKPGPIG 156

Query: 198 VIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLA 257
           V   SG     +   +   G G++  +  G    +  V G S    L +  AD +++ +A
Sbjct: 157 VFSRSGGQSGTIPWVLKEGGFGVSTVVHTG----TEPVLGTSMADLLPLFEADPQTKGVA 212

Query: 258 FVSKPPAEAVRL-KIVNAMKATGKPTVALFLGYTPAVARD 296
             S+           V A     KP V    G      + 
Sbjct: 213 VFSEIGGSQEEECAEVIASGKFTKPFVIYVAGAWAPEGQR 252


>UniRef50_UPI000023F548 hypothetical protein FG11485.1 n=1 Tax=Gibberella zeae PH-1
           RepID=UPI000023F548
          Length = 320

 Score =  102 bits (254), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 45/218 (20%), Positives = 92/218 (42%), Gaps = 15/218 (6%)

Query: 91  QLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMM-FSD 149
              +G  ++  L        A Q +   N +L+ V   +AA    +A++  + +++   +
Sbjct: 80  SPKKGGTTNLDLPVFATVRGAAQSVRP-NASLVHVPASFAAGAIEEAIEAEIPLIVAIVE 138

Query: 150 NVTLEDEIQLKTRAR-EKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTG 205
           ++ + D +++    R +    + GP+    +  G     +  A+    G +G+I  SGT 
Sbjct: 139 HIPVHDMLRVHEILRTQSKSRLKGPNTPGILAPGKCRIGIIPADQCAPGKVGIISRSGTM 198

Query: 206 IQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPP-- 263
           I E       AG+  +  +GLGG      + G +   ALE+L  D  +E +  + +    
Sbjct: 199 IYEAIGATMRAGQVQSLVLGLGGD----SMPGTTMKEALEVLLHDSATETIILIGEIGGS 254

Query: 264 AEAVRLKIVNAMKATG---KPTVALFLGYTPAVARDEN 298
           AE    +++ + +A     KP +++  G T    R   
Sbjct: 255 AEVEAAELLKSFRAENGMFKPVISIISGRTAPPGRAMG 292


>UniRef50_P74286 Succinyl-CoA synthetase n=7 Tax=Chroococcales RepID=P74286_SYNY3
          Length = 302

 Score =  101 bits (251), Expect = 8e-20,   Method: Composition-based stats.
 Identities = 45/207 (21%), Positives = 77/207 (37%), Gaps = 12/207 (5%)

Query: 109 DSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQLKTRAREKG 167
           D A + +   +++LI        + A +A+   +  +++ S  V   D I L   A+   
Sbjct: 56  DLAVKTVGPVDISLILNPPYRVLDAALEAIAAGIRQLVIVSAGVPPLDMITLLREAQATH 115

Query: 168 LLVMGPDCGTSMIA---GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
            L++G      MI           N    G IG+I        ++   ++ AG G +  I
Sbjct: 116 TLILGSGSQGIMIPQQFSVGTLDPNCYLPGPIGIISHCDRLTDDIAQTLSAAGLGQSMVI 175

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
            LG   L+    G +    L++L  DE++  +  + +P +            A  KP VA
Sbjct: 176 SLGTDGLN----GSNFEQWLQVLEEDEQTATILLLGQPNSNGEMRAADYVASAIEKPVVA 231

Query: 285 LFLGYTPAVARDENVWFASSLDEAARL 311
              G    + R     F  SL   A  
Sbjct: 232 YLAGRGAKIKR----HFGDSLTIVANQ 254


>UniRef50_C4XQK6 Succinyl-CoA synthetase beta chain/succinyl-CoA synthetase alpha
           chain n=1 Tax=Desulfovibrio magneticus RS-1
           RepID=C4XQK6_DESMR
          Length = 705

 Score =  101 bits (251), Expect = 8e-20,   Method: Composition-based stats.
 Identities = 53/301 (17%), Positives = 99/301 (32%), Gaps = 17/301 (5%)

Query: 51  FWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQL-EEALKQLAQGSGSSQALTQVRRWD 109
                  +  P D  V ++     AG A A   +     +            +  +  +D
Sbjct: 410 LPLPSLLDLGP-DSGVLVQGLTGRAGRAHARRMRAYGTPVVAGVTPFRGGSEVDGLPVYD 468

Query: 110 SACQKLP--DANLALISVAGEYAAELANQALDRNL-NVMMFSDNVTLEDEIQLKTRAREK 166
           +  + +   D  L++I V    AA+   +A    +  ++  +D +   D + ++     +
Sbjct: 469 TVAEAMGRHDIALSVIFVPAAGAADAIEEAAAAGVARIVCITDGIPQRDMLSVRAALAGR 528

Query: 167 GLLVMGPDCGTSMIAG----TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITH 222
              ++GP+    ++ G      +        G + +   SGT   E+ S++  AG G   
Sbjct: 529 QTTLVGPNTPGLILPGQWFSAGIMPTEPFTPGPVAIFSRSGTLTYEVASRLTAAGIGQAL 588

Query: 223 AIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMK-ATGKP 281
           A G+GG       GG   +   EM+  D +   +  + +    A              KP
Sbjct: 589 AAGMGGDPF----GGAGFVELCEMVRDDARVRAVMVIGEVGGTAEEELAEYVASTKYPKP 644

Query: 282 TVALFLGYTPAVAR---DENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYT 338
             A   G +    R               AA+LACL          +  V+      L  
Sbjct: 645 VAAFVAGVSAPPGRTLGHAGALLERPGGVAAKLACLARAGIPVCEELGEVAGVMAEALCR 704

Query: 339 G 339
           G
Sbjct: 705 G 705


>UniRef50_A2QQL8 Contig An08c0100, complete genome n=3 Tax=Leotiomyceta
           RepID=A2QQL8_ASPNC
          Length = 355

 Score =  100 bits (248), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 45/219 (20%), Positives = 80/219 (36%), Gaps = 18/219 (8%)

Query: 92  LAQGSGSSQALTQVRRWDSACQK-LPDANLALISVAG-EYAAELANQALDRNLNVMMFSD 149
                G    L       +A ++  PDA  + I V G + A  +          V+  ++
Sbjct: 79  KPGVEGEHLGLPVFPSVKAAQERAKPDA--SAIYVPGNQTAKAIEEAIEAEIPLVVAVAE 136

Query: 150 NVTLEDEIQLKTRAR-EKGLLVMGPDCGTSMIAG----TPLAFANVMPEGNIGVIGASGT 204
           +V + D +++ +  + +    ++G +C   + A                GNIG++  SGT
Sbjct: 137 HVPIHDILRIHSMLKTQSKTRLVGANCPGIISAIGKCRIGFQPLPCFAPGNIGIVAKSGT 196

Query: 205 GIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPA 264
              E  +    AG G +  I +GG  L     G + + AL++   D  ++ +  V +   
Sbjct: 197 LSYETVASTTRAGLGQSLCISMGGDVL----AGTNFVDALKIFEDDPDTDGIILVGEIGG 252

Query: 265 EAVRL-----KIVNAMKATGKPTVALFLGYTPAVARDEN 298
            A        K  N   A  KP + L  G      R   
Sbjct: 253 TAEIDAAEWIKDYNQRTANPKPIMGLVGGLHAPPGRIMG 291


>UniRef50_B6H3H8 Pc13g13290 protein n=23 Tax=cellular organisms RepID=B6H3H8_PENCW
          Length = 676

 Score = 97.4 bits (241), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 43/219 (19%), Positives = 79/219 (36%), Gaps = 18/219 (8%)

Query: 92  LAQGSGSSQALTQVRRWDSACQK-LPDANLALISVAG-EYAAELANQALDRNLNVMMFSD 149
                G    L       +A  +  PDA  + I V G + A  +          V+  ++
Sbjct: 74  KPGVEGEHLGLPVFPSVKAAQDRAKPDA--SAIYVPGNQTAKAIEEAIEAEIPLVVAVAE 131

Query: 150 NVTLEDEIQLKTRAR-EKGLLVMGPDCGTSMIAG----TPLAFANVMPEGNIGVIGASGT 204
           +V + D +++ +  + +    ++G +C   + A                G++G++  SGT
Sbjct: 132 HVPIHDILRIHSMLQTQSKTRLVGANCPGIISAIGKCRIGFQPLPCFAPGDVGIVAKSGT 191

Query: 205 GIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPA 264
              E  +    AG G +  I +GG  L     G + + AL +   D  +  +  V +   
Sbjct: 192 LSYETVASTTRAGLGQSLCISMGGDVL----AGTNFVDALNLFENDPDTRGIILVGEVGG 247

Query: 265 EAVRLK---IVNAMKAT--GKPTVALFLGYTPAVARDEN 298
            A       I +  + T   KP +AL  G      R   
Sbjct: 248 TAEMDAAEWIKDYRRRTVDPKPIMALVGGLEAPPGRIMG 286


>UniRef50_Q0UIC0 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
           RepID=Q0UIC0_PHANO
          Length = 661

 Score = 96.7 bits (239), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 44/216 (20%), Positives = 88/216 (40%), Gaps = 18/216 (8%)

Query: 92  LAQGSGSSQALTQVRRWDSACQKL-PDANLALISVAGEYAAELANQALDRNLNVMM-FSD 149
             +GSG       +    +A ++L PDA    I VA   A     +A++  + +++  ++
Sbjct: 81  KPKGSGEHLGKPVLPSVRAAMEQLKPDATG--IYVAAHQATAAIEEAIEAEVPLIVAVAE 138

Query: 150 NVTLEDEIQLKTRAREK-GLLVMGPDCGTSMIAG----TPLAFANVMPEGNIGVIGASGT 204
           ++ L D +++ +  + +    ++G +    + A                G+IG++  SGT
Sbjct: 139 HIPLHDIMRIHSMLQSQSKSRLVGANAPGIISAIGRCRIGFQPLPTFSPGHIGIVAKSGT 198

Query: 205 GIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPA 264
              E    +  AG G +  I +GG      + G + + AL++   DE +E +  V +   
Sbjct: 199 LSYETVGSLTRAGLGQSLCIAVGGD----VIAGTNFVDALKVFEKDEDTEAIILVGELGG 254

Query: 265 ---EAVRLKIVNAMKATG--KPTVALFLGYTPAVAR 295
              E     I +  K     KP  A   G+  +  +
Sbjct: 255 TSEEEAAAWIKDYRKRVKNPKPIAAAIGGFQASPGK 290


>UniRef50_B0JJU2 Succinyl-CoA synthetase alpha chain n=3 Tax=Chroococcales
           RepID=B0JJU2_MICAN
          Length = 295

 Score = 94.4 bits (233), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 40/201 (19%), Positives = 80/201 (39%), Gaps = 11/201 (5%)

Query: 98  SSQALTQVRRWDSACQKLPDAN---LALISVAGEYAAELANQALDRNL-NVMMFSDNVTL 153
             + + ++  +D   + + +A     +LI V      + A +A+   +  +++ +  V  
Sbjct: 42  GGEIIAEIPVFDLVAEAVAEAGEIKTSLILVPPNQVLDAALEAIAAAIPQLIIVTPGVPP 101

Query: 154 EDEIQLKTRAREKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTGIQELC 210
            D ++L   A   G L++GP     +I       +   N    G IG+I        E+ 
Sbjct: 102 LDLVELLKIASTTGTLILGPGSQGVIIPNYLWLGICEPNFYQSGTIGLITRGDRIGDEVA 161

Query: 211 SQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK 270
             +  AG G + A+ LG    +  + G +    L++   D+ +E +  VS+   +A    
Sbjct: 162 KTLTAAGYGESMAVNLG----TDGIIGSNLSQWLQVFEEDDNTEAILLVSQVGGKAEIEA 217

Query: 271 IVNAMKATGKPTVALFLGYTP 291
                 A  KP +A  +G   
Sbjct: 218 AKYIASAIEKPVIAYLVGLNA 238


>UniRef50_Q4PDB0 Putative uncharacterized protein n=1 Tax=Ustilago maydis
           RepID=Q4PDB0_USTMA
          Length = 357

 Score = 93.2 bits (230), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 31/224 (13%), Positives = 69/224 (30%), Gaps = 23/224 (10%)

Query: 89  LKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMM-F 147
           +     GS                      +   + V    AA+   +A++  + +++  
Sbjct: 85  VAPGKGGSKHLGGRPVFNSIKQVLDAGIRVDATSVFVPPALAADAIIEAINAEIPLIVSV 144

Query: 148 SDNVTLEDEIQLKTRAREK-GLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASG 203
           ++ V ++D+ ++      +    ++G +             ++       G +G++  SG
Sbjct: 145 AEGVPVKDQFRVMEALHSQSKSRLLGANSPGFCNPRGCRMGISPLITCAPGPVGIVSRSG 204

Query: 204 TGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPP 263
           T   E     A    G ++ +GLGG        G   + ALE L  D  ++ +    +  
Sbjct: 205 TLSYEAAY--ATKPIGQSYILGLGGD----FYPGTRTVEALEFLFNDPNTQAIVLAGEIG 258

Query: 264 AEAVRL------------KIVNAMKATGKPTVALFLGYTPAVAR 295
                             +  +      KP V    G      +
Sbjct: 259 GTMEEEVYALLHDPNCKYRQAHDKDKFVKPIVGFIAGLNTPPGQ 302


>UniRef50_B3QY35 ATP-citrate lyase/succinyl-CoA ligase n=13 Tax=Chlorobiaceae
           RepID=B3QY35_CHLT3
          Length = 617

 Score = 88.6 bits (218), Expect = 5e-16,   Method: Composition-based stats.
 Identities = 45/218 (20%), Positives = 82/218 (37%), Gaps = 17/218 (7%)

Query: 100 QALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDR-NLNVM-MFSDNVTLEDEI 157
           + +    +   A  + P+ + ALI +  E A   A +AL+  N+ ++ M ++ V  +D  
Sbjct: 61  ENIPVYSQLSEALSEHPNIDTALIYIGAERAFGAAKEALEAKNIKLVSMITEGVPEKDAR 120

Query: 158 QLKTRAREKGLLVMGPDCGTSMIAG------TPLAFANV-----MPEGNIGVIGASGTGI 206
           +L   A++   +  GP     + AG          F N+        G+ GVI  SG   
Sbjct: 121 RLAKIAKQNSKIFNGPSSIGILTAGGCRLGVIGGEFNNLKKCLLYRPGSFGVITKSGGLS 180

Query: 207 QELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEA 266
            E     A  G+GI+  + +GG        G   +T LEM   D  ++ +  V +     
Sbjct: 181 NETMWLCAQNGDGISTTVSIGGD----AYPGTDFVTYLEMFEQDLDTKAVVIVGEVGGSL 236

Query: 267 VRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASS 304
                        +  +   +G T      + + F  +
Sbjct: 237 EEEAAEWFAAKKRRIRLIGVVGGTCQEVLPQGMKFGHA 274


>UniRef50_C0RYI8 Succinyl-CoA synthetase beta chain n=6 Tax=Onygenales
           RepID=C0RYI8_PARBP
          Length = 694

 Score = 87.8 bits (216), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 49/245 (20%), Positives = 95/245 (38%), Gaps = 24/245 (9%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQ-KLPDANLALIS 124
           + +  + A A + +++    +          G    L        A Q   PDA    I 
Sbjct: 65  IYVTGKQATANVKESLAWGTKIIGGVKPGVEGEHLGLPVFPSVKVAQQISRPDATA--IY 122

Query: 125 VAGEYAAELANQALDRNLNVMM-FSDNVTLEDEIQ----LKTRAREKGLLVMGPDCGTSM 179
           V G   A+   +A++  + +++  +++V + D ++    LKT+++ +   ++G +C   +
Sbjct: 123 VPGPQTAQAIEEAIEAEIPLIVAVAEHVPIHDIVRVHAMLKTQSKSR---LVGANCPGII 179

Query: 180 IAG----TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREV 235
            A                G+IG++  SGT   E  +  + AG G +  IG+GG  L    
Sbjct: 180 SAIGKCRIGFQPLPCFSPGHIGIVAKSGTLGYETVASTSRAGLGQSLCIGMGGDVL---- 235

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKI-----VNAMKATGKPTVALFLGYT 290
            G   + AL +   D+ +  +  V +    A               A  KP +A+  G  
Sbjct: 236 AGTDFVDALSIFEHDDDTHGIIIVGEIGGTAEIAAAEWIAHYRRRSANPKPIMAVICGIH 295

Query: 291 PAVAR 295
             + R
Sbjct: 296 APLGR 300


>UniRef50_A7LNF0 ATP citrate lyase n=4 Tax=Toxoplasma gondii RepID=A7LNF0_TOXGO
          Length = 1281

 Score = 87.0 bits (214), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 51/258 (19%), Positives = 95/258 (36%), Gaps = 27/258 (10%)

Query: 102 LTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRN---LNVMMFSDNVTLEDEIQ 158
           L   +    A Q  PD ++ +   +   AA +   AL+       +++ ++ V   +  Q
Sbjct: 724 LPVYQTLQEAVQHFPDVSVLINFASMRSAASVTRLALETAPQLRTIVVIAEGVPEREARQ 783

Query: 159 LKTRAREKGLLVMGPDCGTSM------IAGTPLAFANVM-----PEGNIGVIGASGTGIQ 207
           L    R +G+ ++GP     +      I  T     NVM       G++G +  SG  + 
Sbjct: 784 LAAETRARGVCLIGPATVGGIKSGAFRIGNTGGTLENVMNARLYRPGSVGCVTKSGGMLN 843

Query: 208 ELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAV 267
           E+ + +++  +G   AI +GG        G S L  L     +   ++L  + +     +
Sbjct: 844 EMNNILSIVSDGTYEAIAIGGDRFP----GTSMLDHLLRFERNPDIKLLVLLGEVGG-GM 898

Query: 268 RLKIVNAMK--ATGKPTVALFLG------YTPAVARDENVWFASSLDEAARLACLLSRVT 319
             ++V A+K     KP +A  +G       T         W  S+ + A      L    
Sbjct: 899 EYEVVEAIKDGRLTKPLIAWCVGTCASLFSTEVSFGHAGAWAGSNREHAVAKNAALKAAG 958

Query: 320 ARRNAIAPVSSGFICGLY 337
           A   +        I  +Y
Sbjct: 959 AFVPSSFDELGKSIRHVY 976


>UniRef50_D2RGD1 Acetyl coenzyme A synthetase (ADP forming), alpha domain protein
           n=3 Tax=Archaea RepID=D2RGD1_ARCPR
          Length = 663

 Score = 86.6 bits (213), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 83/496 (16%), Positives = 174/496 (35%), Gaps = 56/496 (11%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
           +A+       G     +++ L +   ++   +   + +  V  + S      + +LA+I+
Sbjct: 10  IAVIGATPKEGKVGNTLLKNLSKFKGKIYAVNPKYREVLGVECYPSVKDLPEEVDLAVIA 69

Query: 125 VAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSM 179
           V  E   ++  +  ++ +   +     F +    + E++L    ++ G+ ++GP+C   +
Sbjct: 70  VPAEVVPKVLEECGEKGVKAAVVISAGFREVGNYKLEMELVEICKKYGIKMVGPNCLGII 129

Query: 180 --IAGTPLAFANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVG 236
               G    F+ V P  G I +I  SG  I  +         G +  + LG + L  E  
Sbjct: 130 NTSNGLNATFSGVEPLRGRIALISQSGALIVAIMDWALANNIGFSKIVSLGNKALLNEC- 188

Query: 237 GISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARD 296
                  +E LS D+++EV+A   +        + +   +   KP VA+  G T A A+ 
Sbjct: 189 -----DFIEYLSNDDETEVIALYVE--GIEEGRRFMEIAEKCRKPIVAIKSGKTSAGAKA 241

Query: 297 ENVWFASSLD--EAARLACLLSRVTARRNAIA----PVSSGFICGLYTGGTLAAEAAGLL 350
            +    S     EA R A   S V    +            +I G + GG     A    
Sbjct: 242 VSSHTGSLAGSYEACRTAFRQSGVVEAESVEELFDFSTVLSYIKG-FRGGV----AIVTN 296

Query: 351 AGHLGVEADDTHQHGMM-LDADSHQIIDLGDDFYTVGRPHPMIDP--TLRNQLIADL--- 404
           +G   V A D  +   + L +  H+ +++       G  +  +D       +        
Sbjct: 297 SGGPAVMASDAVEKYNLNLASFEHETVEMLRSIAPYGNVYNPVDVLGDADAERFCKALDI 356

Query: 405 -GAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQC 463
                 V ++L               ++++        ++  + +     V G     + 
Sbjct: 357 VAKDRNVGLIL---------------AILTPTATIDGVKVAEKIVGINKKVVGCFMGGKS 401

Query: 464 RSQQIATLEDAGIAVVSSLPEATLL-AAALIHPLSPAAQQHTPSLLENVAV---INIGLR 519
             + +  L + GIA  +    A    A+   +      ++     ++   V   +  GL 
Sbjct: 402 FEEAVRILREKGIANFNDPVRAVKAIASVQFYSRRTKRKEFVRFDVDLKKVRELLKRGL- 460

Query: 520 SFALELQSASKPVVHY 535
            +   ++    PV  Y
Sbjct: 461 -YFEVVREYGIPVPPY 475


>UniRef50_A9USL5 Predicted protein n=2 Tax=cellular organisms RepID=A9USL5_MONBE
          Length = 1085

 Score = 86.6 bits (213), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 40/245 (16%), Positives = 91/245 (37%), Gaps = 18/245 (7%)

Query: 102 LTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDR-NLNVM-MFSDNVTLEDEIQL 159
           +   ++   A ++ PD ++ +   +   A E   +AL+   + V+ + ++ +      +L
Sbjct: 528 IPVFQQMGEAMERHPDVDVLINFASFRSAYESTLEALEYPQIKVIAIIAEGIPEHLTRKL 587

Query: 160 KTRAREKGLLVMGPDCGTSMIAG------TPLAFANVM-----PEGNIGVIGASGTGIQE 208
              A+ KG+ ++GP     +  G      T     N++       G++  +  SG    E
Sbjct: 588 IKVAQAKGVTIIGPATVGGIKPGCFKIGNTGGMIDNIISSKLYRPGSVAYVSRSGGMSNE 647

Query: 209 LCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVR 268
           L + I+    G+   + +GG        G   +  L     D + +++  + +       
Sbjct: 648 LNNIISRNTNGVYEGVAIGGD----RYPGSVFIDHLFRFQDDPEVKMMVLLGEVGGVEEY 703

Query: 269 LKIVNAMK-ATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAP 327
                       KP VA  +G   ++   E  +  +     + +   +++  A + A A 
Sbjct: 704 EICRAIASGRLNKPIVAWCIGTCGSMFTSEVQFGHAGACANSDMETAVAKNKALKEAGAI 763

Query: 328 VSSGF 332
           V   F
Sbjct: 764 VPPSF 768


>UniRef50_D1ZL53 Whole genome shotgun sequence assembly, scaffold_53 n=2
           Tax=Sordariaceae RepID=D1ZL53_SORMA
          Length = 625

 Score = 86.3 bits (212), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 41/215 (19%), Positives = 78/215 (36%), Gaps = 35/215 (16%)

Query: 92  LAQGSGSSQALTQVRRWDSACQKL-PDANLALISVAGEYAAELANQALDRNLNVMM-FSD 149
               +G    L  +     A ++L PDA    I VA   A     +A++  + +++  ++
Sbjct: 29  TPGRTGEHIGLPVLPSVRQAMEQLKPDATA--IYVAAHQAPGAIEEAIEAEVPLIVAVAE 86

Query: 150 NVTLEDEIQLKTRAR-EKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQE 208
           ++ + D +++ +  + +    ++GP+    + A            G   +  AS T    
Sbjct: 87  HIPVHDMLRIHSILKTQSKSRLVGPNSPGIISA-----------VGKCRIAVASTT---- 131

Query: 209 LCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVR 268
                  AG G +  IG+GG        G   + AL +L  D  +E +A + +       
Sbjct: 132 ------RAGLGQSLCIGVGGD----MAPGTDMVEALSVLEKDPDTEAIALIGEIGGTGEL 181

Query: 269 L-----KIVNAMKATGKPTVALFLGYTPAVARDEN 298
                 K   +   + KP V L  G   A      
Sbjct: 182 EAAAWIKEYYSRSESPKPIVGLIAGVNEAPGHIMG 216


>UniRef50_A8ZSQ9 CoA-binding domain protein n=1 Tax=Desulfococcus oleovorans Hxd3
           RepID=A8ZSQ9_DESOH
          Length = 516

 Score = 85.5 bits (210), Expect = 5e-15,   Method: Composition-based stats.
 Identities = 51/260 (19%), Positives = 87/260 (33%), Gaps = 41/260 (15%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNL--NVMMFSDNVTLED 155
              ++  V  + S      + +LA+I V      ++ +  +D+ +   V++ S    L +
Sbjct: 64  KEASVHGVPAFASVKDIQDEIDLAVIIVPAAGVPDIISDCVDKGIGAAVVITSGFGELGE 123

Query: 156 E-----IQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMP-----EGNIGVIGASGTG 205
           E      ++  RAR  G++++GP+     IA     F    P      G IG+   SG  
Sbjct: 124 EGKGLQNEMLRRARAGGMVLVGPN--GQGIAAPESKFYPWFPTFRPDPGVIGIASQSGGI 181

Query: 206 IQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAE 265
             EL  Q+A  G G +  I  G          +S    L     D  ++V+    +   +
Sbjct: 182 STELSEQLAEFGFGCSKVISTG------NCADLSWPDYLAYFRQDPSTKVVLLYMEGAQD 235

Query: 266 AVRLKIVNAMKATGKPTVALFLGYTPAVAR---------------------DENVWFASS 304
                      A  KP + +  G T    R                        +  A +
Sbjct: 236 GRAFFREAKKTALEKPVILIKSGRTQEGGRAASSHTGSMAGSDAVFDGVCKQAGLIRAKT 295

Query: 305 LDEAARLACLLSRVTARRNA 324
           L+EA  LA         R  
Sbjct: 296 LEEAVVLAAAFVTTPLPRGR 315


>UniRef50_A5D2I4 Succinyl-CoA synthetase, alpha subunit n=1 Tax=Pelotomaculum
           thermopropionicum SI RepID=A5D2I4_PELTS
          Length = 162

 Score = 85.5 bits (210), Expect = 5e-15,   Method: Composition-based stats.
 Identities = 25/120 (20%), Positives = 56/120 (46%), Gaps = 5/120 (4%)

Query: 91  QLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMF-SD 149
              +G  + + +        AC+     + +++ +   +  + A ++L+  + V++  ++
Sbjct: 40  TPGKGGATVEGIPVYNSVREACENHR-IDASVLFIPAPFTKDAAFESLEAGVPVVVIVTE 98

Query: 150 NVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGASGTGI 206
            V + DEIQ+   A+ KG +V+GP+      +G     +       EG +GV+  SGT +
Sbjct: 99  GVPVHDEIQIVAFAKRKGAIVLGPNTFGICSSGKCKIGIPPNQYFVEGPVGVVSRSGTLL 158


>UniRef50_C5P5I2 Succinyl-CoA synthetase beta chain, putative n=9 Tax=cellular
           organisms RepID=C5P5I2_COCP7
          Length = 712

 Score = 85.1 bits (209), Expect = 6e-15,   Method: Composition-based stats.
 Identities = 44/219 (20%), Positives = 81/219 (36%), Gaps = 18/219 (8%)

Query: 92  LAQGSGSSQALTQVRRWDSACQK-LPDANLALISVAGEYAAELANQALDRNLNVMM-FSD 149
                G    L        A +K  PDA    + V G   A    +A++  + +++  ++
Sbjct: 107 KPGVEGEHLGLPVFPSVRVAQEKARPDATA--VYVPGNQTAAAIEEAIEAEIPLVVAVAE 164

Query: 150 NVTLEDEIQLKTRAR-EKGLLVMGPDCGTSMIAG----TPLAFANVMPEGNIGVIGASGT 204
           +V + D +++ +  R +    ++G +C   + A                G++G++  SGT
Sbjct: 165 HVPIHDILRIHSILRTQSKTRLVGANCPGIISAIGKCRIGFQPLPCFSSGHVGIVAKSGT 224

Query: 205 GIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPA 264
              E  +    AG G +  IG+GG  L     G   + AL++   D+ +  +  V +   
Sbjct: 225 LSYETVASTTRAGLGQSLCIGMGGDVL----AGTDFVDALKVFEHDDDTHGIIIVGEIGG 280

Query: 265 EAVRL-----KIVNAMKATGKPTVALFLGYTPAVARDEN 298
            A        K      A  KP + L  G      R   
Sbjct: 281 TAEMDAAEWIKDYRRRTANPKPIMGLVGGIEAPHGRIMG 319


>UniRef50_Q251K7 Putative uncharacterized protein n=1 Tax=Desulfitobacterium
           hafniense Y51 RepID=Q251K7_DESHY
          Length = 188

 Score = 84.7 bits (208), Expect = 7e-15,   Method: Composition-based stats.
 Identities = 33/152 (21%), Positives = 59/152 (38%), Gaps = 15/152 (9%)

Query: 156 EIQLKTRAREKGLLVMGPDC------GTSMIAGTPLAFANVMPEGNIGVIGASGTGIQEL 209
            +QL+  A EK  +V+G +       G +M+   P     V   G +GV+  SG+   E+
Sbjct: 1   MMQLRKIALEKQAMVIGGNTTGIISTGKAMMGFFPYWLDRVYKPGRVGVMTRSGSLTNEV 60

Query: 210 CSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPA---EA 266
            ++I  AG G +  +G+GG  +            L +   D  ++ +  + +      E 
Sbjct: 61  TAEIVKAGFGPSSIVGVGGDPVPL----TRFAEILPLFEKDPDTDAVVMIGEIGGTMEED 116

Query: 267 VRLKIVNAMKATGKPTVALFLGYTPAVARDEN 298
           V   I   +    KP +    G T    +   
Sbjct: 117 VAEAIEQRI--FTKPLIGFMGGRTAPKGQKMG 146


>UniRef50_Q2LPK8 Succinyl-CoA synthetase, alpha subunit n=1 Tax=Syntrophus
           aciditrophicus SB RepID=Q2LPK8_SYNAS
          Length = 180

 Score = 82.8 bits (203), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 28/165 (16%), Positives = 48/165 (29%), Gaps = 31/165 (18%)

Query: 177 TSMIAG---TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
             ++ G     +  A++   G +G+I  SGT   E    ++    G +  +G+G   +  
Sbjct: 16  GILVPGKGKMGIMPASMFAPGRVGIISRSGTLSYEFAGILSENNVGQSTVVGMGADPVVL 75

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG----- 288
                +    LE+   DE ++ +  V +   E          +   KP  A   G     
Sbjct: 76  ----RNLTDILELFEEDEGTDAVIVVGEVGGEQEEKAAGFIKRRMTKPVAAYIAGRYSPQ 131

Query: 289 -------------------YTPAVARDENVWFASSLDEAARLACL 314
                                    RD  V    S    A  A  
Sbjct: 132 GKRMGHAGAIVRGASGTVAGKQEALRDAGVTILDSPIHVADWAVK 176


>UniRef50_O93988 ATP-citrate synthase subunit 1 n=373 Tax=root RepID=ACL1_SORMA
          Length = 674

 Score = 82.4 bits (202), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 43/235 (18%), Positives = 90/235 (38%), Gaps = 26/235 (11%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRN--LNVMMFSDNVTLED 155
           S   L   +    A  K PD ++ +   +         + ++      + + ++ V    
Sbjct: 106 SETLLPVYQEVQKAIAKHPDVDVVVNFASSRSVYSSTMELMEHPQIKTIAIIAEGVPERR 165

Query: 156 EIQLKTRAREKGLLVMGPDCGTSMIAG------TPLAFANVM-----PEGNIGVIGASGT 204
             ++   A++KG+ ++GP     +  G      T     N++      +G++G +  SG 
Sbjct: 166 AREIAYVAKKKGITIIGPATVGGIKPGCFKIGNTGGMMDNIVASKLYRKGSVGYVSKSGG 225

Query: 205 GIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPA 264
              EL + I+   +G+   + +GG        G + +  L    AD   ++L  + +   
Sbjct: 226 MSNELNNIISQTTDGVYEGVAIGGD----RYPGTTFIDHLLRYQADPACKILVLLGEVGG 281

Query: 265 EAVRLKIVNAMKA--TGKPTVALFLGYTPAVARDE------NVWFASSLDEAARL 311
                K++ A+K     KP VA  +G   ++ + E        +  S L+ AA  
Sbjct: 282 VE-EYKVIEAVKQGIITKPIVAWAIGTCASMFKTEVQFGHAGAFANSQLETAATK 335


>UniRef50_A9ICA6 Acetyl-CoA synthetase n=1 Tax=Bordetella petrii DSM 12804
           RepID=A9ICA6_BORPD
          Length = 704

 Score = 82.4 bits (202), Expect = 5e-14,   Method: Composition-based stats.
 Identities = 49/260 (18%), Positives = 99/260 (38%), Gaps = 24/260 (9%)

Query: 62  NDICVAIRSEAADAGIAQA-IMQQLEEALKQLAQGSGSSQ--ALTQVRRWDSACQKLPDA 118
           N + +A+   +AD        ++ L  A         + +  A+  ++ + S      D 
Sbjct: 15  NPLSIAVIGASADEDKIGGRPIKYLRLAGYSGPIYPINPKRDAIHGLKCYPSITAVDDDI 74

Query: 119 NLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEI------QLKTRAREKGLLVM 171
           +LA+ISV  +         + + ++ V++FS   +  DE       ++   A E G+ ++
Sbjct: 75  DLAIISVPAQEVLSAVESCVAKRVSGVLIFSSGFSEVDEAGRILQERIVQLASEGGVALL 134

Query: 172 GPDCGTSMIAGTPL--AFANVM-----PEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           GP+C  +      L   F++ +       G+I  +  SG     +         G++  +
Sbjct: 135 GPNCAGTFNTRAGLLATFSSGILDKPPQPGSISFVSQSGAFGINMLVLAGERDLGLSMCL 194

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVL-AFVSKPPAEAVRLKIVNAMKATGKPTV 283
             G +        +    AL  ++ D ++EV+   +   P     L  +   +   KP +
Sbjct: 195 TSGNQ------ADVDVAEALAYMAQDPETEVIGVCIEGIPDFDRFLAAIELARRNRKPVI 248

Query: 284 ALFLGYTPAVARDENVWFAS 303
            L LG +   AR      AS
Sbjct: 249 VLKLGRSEVGARAVASHTAS 268


>UniRef50_Q8TVZ2 Acyl-CoA synthetase (NDP forming) n=1 Tax=Methanopyrus kandleri
           RepID=Q8TVZ2_METKA
          Length = 446

 Score = 80.1 bits (196), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 78/408 (19%), Positives = 126/408 (30%), Gaps = 75/408 (18%)

Query: 119 NLALISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGP 173
           +LA+I+V      E+  +A +  +   +     FS+    + E +L   AR+ G+ ++GP
Sbjct: 65  DLAVIAVPARVVPEVVREAGEAGVPYCVVISAGFSEAGNEDLERELVRTARKVGVRLVGP 124

Query: 174 DCGTSMIAGTPLA---FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
           +C   + A   L     A   P GNI  +  SG       S I     G    +G+G   
Sbjct: 125 NCLGIINARIGLNASFAAESPPPGNIAFVTQSGALA---TSVIDWFSSGDVGTVGVGFSK 181

Query: 231 LSR--EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG 288
                    +     LE L+ D+ ++V+    +   +  R     +  A  KP + L  G
Sbjct: 182 FVSLGNAADLDFPDFLEYLAEDDDTDVVVLYLEGVKDGPRFLDALSECAGRKPVIVLKGG 241

Query: 289 YTPAVARDENVW---------------------FASSLDEA--ARLACLLSRVTARRNAI 325
            T A A                           F    +EA  A      +        +
Sbjct: 242 RTEAGAEAVGTHTGSLAGSGEVYEGLVEGEGGIFVGGFEEAFDAAKLLAKAGPPTSDRVL 301

Query: 326 APVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTV 385
              ++G       GG LA +A   L   L  E            A  + +  LGD     
Sbjct: 302 IVTNAG------GGGILATDALHELGFEL-PEPAGDPSVLPPEAATGNPVDVLGDAD--- 351

Query: 386 GRPHPMIDPTLRNQLIADLGAKPQ----VRVLLLDVVIGFGATADPAASLVSAWQK-ACA 440
                      R ++  +  A P     V V+L            P +         A  
Sbjct: 352 ---------AERYRVALEEFADPDRYGAVMVIL-----------TPQSVTEPVKTARAVV 391

Query: 441 ARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLL 488
             ++  P   I    G        +  I  LE+ G+    S   A   
Sbjct: 392 EFVEEFPGPVIGVWMGR----HSVALGIRVLEEGGVPTFPSPERAARA 435


>UniRef50_A3DLQ0 Acetyl-CoA synthetase (ADP-forming) alpha subunit / branched-chain
           acyl-CoA synthetase (ADP-forming) alpha subunit n=4
           Tax=Archaea RepID=A3DLQ0_STAMF
          Length = 467

 Score = 80.1 bits (196), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 53/291 (18%), Positives = 101/291 (34%), Gaps = 40/291 (13%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQLAQGSGSSQALT--QVRRWDSACQKLPDANLAL 122
           +AI   +   G     IM+ + E   +      + +A      + + S  +   + ++A+
Sbjct: 16  IAIIGASRSPGKIGHTIMKNIIEYGYKGKIYPINPKADEILGYKAYKSVVEVPDEIDMAI 75

Query: 123 ISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           I V  +   ++A +   + + V++     FS+   +E E +L   AR  G+ ++GP+   
Sbjct: 76  IVVPEQVVPKVAEECGKKGVKVLVVITSGFSEVGNVEAERKLVEIARRYGMRILGPNIFG 135

Query: 178 SMIAGTPL--AFANV-MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSRE 234
                  L   F    + EG I  I  SG         IAL G  I   IG+        
Sbjct: 136 IAYTPAKLNATFGPKDVLEGPIAFITQSGALG------IALMGWTIMEEIGISALVSMGN 189

Query: 235 VGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKA--TGKPTVALFLGYT-- 290
           +  I  +   + L+ D  ++V+    +        K +  MK     KP + +  G +  
Sbjct: 190 MADIDVIDVSKYLANDPNTKVITIYLEGLKPGTGRKFIEEMKKVTVKKPVIVIKAGRSKR 249

Query: 291 -------------------PAVARDENVWFASSLDEAARLACLLSRVTARR 322
                               A  +   +  A + +E    A   +     R
Sbjct: 250 GAAAAASHTGSLAGSDNLYQAAFKQAGIIRAYTTEEMFDWARAFASQPIPR 300


>UniRef50_D1C4Q6 CoA-binding domain protein n=1 Tax=Sphaerobacter thermophilus DSM
           20745 RepID=D1C4Q6_SPHTD
          Length = 280

 Score = 78.9 bits (193), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 43/257 (16%), Positives = 88/257 (34%), Gaps = 24/257 (9%)

Query: 70  SEAADAGIAQAIMQQ---LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVA 126
           +E A A + + ++     +   +     G   +         D+     P A L  I+V 
Sbjct: 17  TEDAAAALTEQMLAYGTPVVAGVAPGRYGDRVAGVPVYNSVADAVLFHQPSATL--IAVP 74

Query: 127 GEYAAELANQALDRNLNVMMF-SDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPL 185
            +   + A +AL  ++ +++  ++ V   D  +L   AR+    V+GP     +     L
Sbjct: 75  PDAVLDAALEALSHDIRLLLIATEFVPERDVQRLLGWARDSAARVLGPGSAGIIAPAARL 134

Query: 186 AFANV--------MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGG 237
               +           G +GVI    T   ++ +     G GI+ A+  G    +  +  
Sbjct: 135 RIGTIGGENPDRNFSPGRVGVIAPGATLAADIAALTRRLGIGISTAVSTG----TAPMVV 190

Query: 238 ISALTALEMLSADEKSEVLAFVSKPP-AEAVRLKIVNAMKATGKPTVALFLGYTPAVAR- 295
            +  + L +   D+ +  +        AE V   I+   +   KP +       P     
Sbjct: 191 TTPASLLPLFERDDATAGVVLAGNAAWAEEVADAIM--AQRYTKPLIVASTDGAPDGTDA 248

Query: 296 --DENVWFASSLDEAAR 310
             D     A   ++  +
Sbjct: 249 LLDAGALVAEEWEDLVQ 265


>UniRef50_Q4SU53 Chromosome 2 SCAF14024, whole genome shotgun sequence. (Fragment)
           n=1 Tax=Tetraodon nigroviridis RepID=Q4SU53_TETNG
          Length = 962

 Score = 78.9 bits (193), Expect = 5e-13,   Method: Composition-based stats.
 Identities = 42/247 (17%), Positives = 93/247 (37%), Gaps = 22/247 (8%)

Query: 102 LTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDR-NLN-VMMFSDNVTLEDEIQL 159
           L   +    A +K P+ ++ +   +   A +   +A+    ++ + + ++ +      +L
Sbjct: 473 LPVYKNMADAMKKHPEVDVVISFASLRSAFDSTIEAMQYSQIHTIAIIAEGIPEAQTRKL 532

Query: 160 KTRAREKGLLVMGPDCGTSMIAG------TPLAFANV-----MPEGNIGVIGASGTGIQE 208
              A +KG+ ++GP     +  G      T     N+        G++  +  SG    E
Sbjct: 533 IKVADDKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNE 592

Query: 209 LCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVR 268
           L + I+   +G+   + +GG        G + +  +         +++  + +       
Sbjct: 593 LNNIISRTTDGVYEGVAIGGD----RYPGSTFMDHVIRYQDTPGIKMIVVLGEIGGSE-E 647

Query: 269 LKIVNAMK--ATGKPTVALFLGYTPAVARDENVWFASSLDEAARLA-CLLSRVTARRNAI 325
            KI   +K     KP V   +G    +   E V F  +   A + +   +++  A R+A 
Sbjct: 648 YKICQGIKEGRITKPLVCWCIGTCATMFASE-VQFGHAGACANQASETAVAKNQALRDAG 706

Query: 326 APVSSGF 332
           A V   F
Sbjct: 707 AYVPKSF 713


>UniRef50_B8F999 CoA-binding domain protein n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8F999_DESAA
          Length = 486

 Score = 77.8 bits (190), Expect = 9e-13,   Method: Composition-based stats.
 Identities = 60/239 (25%), Positives = 88/239 (36%), Gaps = 23/239 (9%)

Query: 96  SGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALD---RNLNVMMFSDNVT 152
           S     +  V       Q     +LA ISV  +   E+  Q L      + V   S    
Sbjct: 51  SDKGGDVLGVPAIAGLEQADGPVDLASISVPAKAVPEILEQCLQNGVAGVQVHT-SGFAE 109

Query: 153 LEDE------IQLKTRAREKGLLVMGPDCGTSMIAGTPL----AFANVMPEGNIGVIGAS 202
           + DE       QL+  A  KGL ++GP+C         L     F      G+  +I  S
Sbjct: 110 MGDEEGIALQKQLEEYA-AKGLRIVGPNCFGIHCPKGGLTVLPGFDFNKQPGSCSMISQS 168

Query: 203 GTGIQELCSQIALAGEGITHAIGLG-GRDLSREVGGISALTALEMLSADEKSEVLAFVSK 261
           G    +   + ALAG GI+  +  G G DL        A+  +E L+ D ++E +A   +
Sbjct: 169 GGLANDFGHEAALAGLGISKVVSFGNGCDL-------DAIALMEYLADDPQTEYIAAYIE 221

Query: 262 PPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTA 320
             A+A     V    A  KP +    G TP   R       S   E+      L++  A
Sbjct: 222 GVADAGAFLDVVRKTAAKKPVIIWKGGLTPLGGRATLSHTGSMGGESKIWEGALAQAGA 280


>UniRef50_P16638 ATP-citrate synthase n=42 Tax=cellular organisms RepID=ACLY_RAT
          Length = 1100

 Score = 77.4 bits (189), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 30/202 (14%), Positives = 74/202 (36%), Gaps = 20/202 (9%)

Query: 102 LTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRN--LNVMMFSDNVTLEDEIQL 159
           +   +    A +K P+ ++ +   +   A +   + ++      + + ++ +      +L
Sbjct: 549 IPVFKNMADAMKKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEALTRKL 608

Query: 160 KTRAREKGLLVMGPDCGTSMIAG------TPLAFANV-----MPEGNIGVIGASGTGIQE 208
             +A +KG+ ++GP     +  G      T     N+        G++  +  SG    E
Sbjct: 609 IKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNE 668

Query: 209 LCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVR 268
           L + I+   +G+   + +GG        G + +  +         +++  + +       
Sbjct: 669 LNNIISRTTDGVYEGVAIGGD----RYPGSTFMDHVLRYQDTPGVKMIVVLGEIGGTE-E 723

Query: 269 LKIVNAMK--ATGKPTVALFLG 288
            KI   +K     KP V   +G
Sbjct: 724 YKICRGIKEGRLTKPVVCWCIG 745


>UniRef50_Q330N6 Acetyl-CoA synthetase (ADP-forming) alpha subunit n=1
           Tax=Haloarcula sp. D1 RepID=Q330N6_9EURY
          Length = 453

 Score = 77.4 bits (189), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 49/242 (20%), Positives = 89/242 (36%), Gaps = 20/242 (8%)

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           P+ + V   SE       +A+   +E           S   L  V   DS      D +L
Sbjct: 4   PSAVAVVGASETEGKIGYEAMANAMEFDGPVYPVNPSSDGDLFGVPFVDSVTDIDDDVDL 63

Query: 121 ALISVAGEYAAELANQALDRNLNVMMF--SDNVTLEDE-----IQLKTRAREKGLLVMGP 173
           AL  V G    ++  +  +  +  ++          DE       +   A E G+ ++GP
Sbjct: 64  ALCCVPGPATPDVVAECGEAGVGAVVIYAGGFAEAGDEGERLQRAVVETAEEYGISLLGP 123

Query: 174 DCGTSMIAGTPL-----AFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
           +    ++  T L     + A  +PEGN  VI  SG     L  Q    G G++  +GLG 
Sbjct: 124 NTSGFVVPATDLLCSFASGAEKLPEGNTAVIAQSGGIAHVLAFQSRRQGRGVSAMVGLGN 183

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG 288
           R        +     +E    D++++ +    +         ++ A + +  P +A  +G
Sbjct: 184 R------ANVGFTETIEYFDGDDRTDAIVLHVE--GTDDGRGLLEACRDSDTPVIAYKVG 235

Query: 289 YT 290
            +
Sbjct: 236 QS 237


>UniRef50_A6TL45 Putative uncharacterized protein n=3 Tax=Clostridiales
           RepID=A6TL45_ALKMQ
          Length = 56

 Score = 76.6 bits (187), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 22/47 (46%), Positives = 29/47 (61%)

Query: 509 ENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ 555
           + + VINIGL SF  +L+      +H  W P AGGNKK+  LL RL+
Sbjct: 10  KQLKVINIGLESFHQDLKKQGVQSIHVDWRPTAGGNKKMVGLLARLK 56


>UniRef50_C7MVA0 Acyl-CoA synthetase (NDP forming) n=1 Tax=Saccharomonospora viridis
           DSM 43017 RepID=C7MVA0_SACVD
          Length = 926

 Score = 75.9 bits (185), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 78/459 (16%), Positives = 143/459 (31%), Gaps = 43/459 (9%)

Query: 65  CVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
            +   +++   G A        +    +   +    A+  VR + S  +     +LA+++
Sbjct: 224 VIGASTDSTKIGYAVLSNLLAADFAGPVYPVNPEHVAVRGVRAYKSVLEIPGPVDLAVVA 283

Query: 125 VAGEYAAELANQALDRNLNVMM-----FSDNVT--LEDEIQLKTRAREKGLLVMGPDCGT 177
           V  +    + + AL + +  ++     F+++    L  E++L   AR  G+ V+GP+   
Sbjct: 284 VPADEVEAVLDGALAKGVQALVIVSAGFAESGPHGLHAELRLVKAARAHGMRVVGPN-AL 342

Query: 178 SMIAGTPLAFANVM------PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
            ++   P    N          G  G    SG     + +     G G++  +  G R  
Sbjct: 343 GVLNTDPTVRLNATLAPRLPRRGRTGFFCQSGALGIAILADAEARGLGLSTFVSAGNR-- 400

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
             +V G   L        D +++V+    +      +   +    A  KP VA       
Sbjct: 401 -ADVSGNDLLQ---YWETDPRTDVVLLYLESFGNPRKFARLARRLARSKPIVA------- 449

Query: 292 AVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLA 351
                           A       S V A       V    +  L+    + A       
Sbjct: 450 ---VKSGRHAVRPQLAATSTEIDESSVQALFEQAGVVRVDTLAQLFDTALVFANQPLPAG 506

Query: 352 GHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVR 411
             +G+  + +    +  D    Q + LG +   VG   P   P      +    A P V 
Sbjct: 507 SRIGIVGNSSAIALLAADTARAQGLTLGIEPVDVGSQAP---PEDFAAAVGRALASPDVD 563

Query: 412 VLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATL 471
            L++  V      A P  +   A ++   A         ++T    E  P       A  
Sbjct: 564 ALVVVFV---PPVATPGTAYARALRETVLATSPTLEKPIVSTFLAAEGVPDEL----AVT 616

Query: 472 EDAGIAVV---SSLPEATLLAAALIHPLSPAAQQHTPSL 507
           +D G        S P       AL   +  A  +  P  
Sbjct: 617 DDDGTVAFGSIPSYPSPERAVNALARVVRYAEWRRRPQG 655


>UniRef50_P53396 ATP-citrate synthase n=53 Tax=root RepID=ACLY_HUMAN
          Length = 1101

 Score = 75.9 bits (185), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 30/202 (14%), Positives = 74/202 (36%), Gaps = 20/202 (9%)

Query: 102 LTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRN--LNVMMFSDNVTLEDEIQL 159
           +   +    A +K P+ ++ +   +   A +   + ++      + + ++ +      +L
Sbjct: 550 IPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEALTRKL 609

Query: 160 KTRAREKGLLVMGPDCGTSMIAG------TPLAFANV-----MPEGNIGVIGASGTGIQE 208
             +A +KG+ ++GP     +  G      T     N+        G++  +  SG    E
Sbjct: 610 IKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNE 669

Query: 209 LCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVR 268
           L + I+   +G+   + +GG        G + +  +         +++  + +       
Sbjct: 670 LNNIISRTTDGVYEGVAIGGD----RYPGSTFMDHVLRYQDTPGVKMIVVLGEIGGTE-E 724

Query: 269 LKIVNAMK--ATGKPTVALFLG 288
            KI   +K     KP V   +G
Sbjct: 725 YKICRGIKEGRLTKPIVCWCIG 746


>UniRef50_Q89PN4 Blr3446 protein n=1 Tax=Bradyrhizobium japonicum RepID=Q89PN4_BRAJA
          Length = 707

 Score = 75.1 bits (183), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 48/244 (19%), Positives = 97/244 (39%), Gaps = 25/244 (10%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVT---- 152
            +  +  ++ + S  +     +LA+I+V  E A E   Q   R +  V++FS        
Sbjct: 51  KAVTVQGLKAYASVAEVPEAPDLAIIAVDAERAGEAVEQCAARGVRSVVVFSSGFAELGE 110

Query: 153 ----LEDEIQLKTRAREKGLLVMGPDCGTSM------IAGTPLAFANVMPE-GNIGVIGA 201
               ++D ++L   AR  G+ ++GP+C  ++      IA   +   + MP  G++G++  
Sbjct: 111 QGRAMQDRLRL--AARNSGMRLLGPNCLGAVSVAEKSIATFSIVLEHSMPAAGSLGIVSQ 168

Query: 202 SGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSK 261
           SG          +  G G++  I  G          +     +  ++ D  ++V+    +
Sbjct: 169 SGNLGSYTMRLASERGVGVSRFITTGNE------CDVDIADGIAWMARDPATKVILCCLE 222

Query: 262 PPAEAVR-LKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTA 320
              +A R +  +   +  GKP +A+ +G + A          +     A    L +R  A
Sbjct: 223 ACRDAGRLISALEEARDAGKPVIAMKIGTSAAGQAAAASHTGAMAGSDAVFDALFARCGA 282

Query: 321 RRNA 324
            R  
Sbjct: 283 VRVR 286


>UniRef50_B6YXJ0 Acetyl-CoA synthetase II (NDP forming), alpha subunit n=5
           Tax=Thermococcaceae RepID=B6YXJ0_THEON
          Length = 459

 Score = 75.1 bits (183), Expect = 7e-12,   Method: Composition-based stats.
 Identities = 33/212 (15%), Positives = 77/212 (36%), Gaps = 15/212 (7%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVT---- 152
             + +  V+ + +      +  LA++ V   +  +      ++ +  +++ +        
Sbjct: 46  KDEVVQGVKAYKNVKDIPDEVELAVVVVPKRFVKQTIIDCGEKGVKGIILITAGFGEVGE 105

Query: 153 --LEDEIQLKTRAREKGLLVMGPDCGTSMI--AGTPLAFANVMPEGNIGVIGASGTGIQE 208
               +E +L   A   G+ ++GP+C   M         F     +G+I  I  SG     
Sbjct: 106 DGKREERELVEIAHRYGMRIVGPNCVGIMNTHNDMNATFVANAKKGDIAFISQSGALGAG 165

Query: 209 LCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVR 268
           +  +    G G +  + +G       +  +     +E L+ D +S+ +A   +   +  +
Sbjct: 166 IIYKTIKEGIGFSKFVSIG------NMADVDFAEFMEYLANDPESKAIALYIEGIKDGRK 219

Query: 269 LKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
              V       KP + L  G + + AR  +  
Sbjct: 220 FMEVAKRVTKKKPVIVLKAGKSESGARAASSH 251


>UniRef50_B8FK52 Acetyl coenzyme A synthetase (ADP forming), alpha domain protein
           n=4 Tax=Proteobacteria RepID=B8FK52_DESAA
          Length = 726

 Score = 74.3 bits (181), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 44/221 (19%), Positives = 88/221 (39%), Gaps = 28/221 (12%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFS-------- 148
            ++++   R + +      D ++A++ V      ++  QA ++  + V++ +        
Sbjct: 49  RARSVVANRAYPTIKDIPDDVDMAVVIVPAPMVVDVVEQAAEKGASGVVVITAGFKEVGG 108

Query: 149 DNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPL----AFANVMP-EGNIGVIGASG 203
           + V LE+E  LK   +E+G+ ++GP+C   +          +FA  MP  GNIG I  SG
Sbjct: 109 EGVKLENE--LKAVVKERGIRLIGPNCLGIINTAPGFSMNASFAQAMPAPGNIGFISQSG 166

Query: 204 TGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPP 263
                +         G +  I  G +    E+        LE L  D  ++V+    +  
Sbjct: 167 AMCTAVLDLAMGRNIGFSKFISFGNKADVSEI------DLLEYLGQDPDTDVILMYLE-- 218

Query: 264 AEAVRLKIVNAMKAT----GKPTVALFLGYTPAVARDENVW 300
                 K ++  +       KP +A+  G +   A+  +  
Sbjct: 219 DITDGRKFMDVARKITWKYKKPMLAIKSGRSEEGAKAVSSH 259


>UniRef50_Q46UX4 CoA-binding n=2 Tax=Cupriavidus RepID=Q46UX4_RALEJ
          Length = 725

 Score = 73.6 bits (179), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 48/234 (20%), Positives = 97/234 (41%), Gaps = 22/234 (9%)

Query: 96  SGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNV-MMFSDNVT-- 152
           + S+  +  +  + S        +LA+I+V    + ++  Q         ++F+      
Sbjct: 46  NASAAEVQGLPAYGSLSDIGEPVDLAIIAVPASASQDVMAQLAGNGTRAAVVFTSGFAEA 105

Query: 153 ----LEDEIQLKTRAREKGLLVMGPDCGTSM-------IAGTPLAFANVMPEGNIGVIGA 201
               ++ + +L   A++ G+ ++GP+C  +M          +P+A +   P G +G++  
Sbjct: 106 GGAGVQMQERLARSAQQAGITLLGPNCLGAMNLRERVFATFSPIALSGTPPVGEVGLVSQ 165

Query: 202 SGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSK 261
           SG       +    AG G++H +  G         G+     +E L+ D  + V+    +
Sbjct: 166 SGAFGAYAFALAREAGLGLSHWVTTGNE------AGLQVADVIEWLAHDPNTRVILAYIE 219

Query: 262 PPAE-AVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFAS-SLDEAARLAC 313
              + A   + + A +A GKP V   +G T A AR      AS + ++A   A 
Sbjct: 220 GCRDGARLRRALAAARAAGKPVVVTKVGTTEAGARSAQSHTASLAGEDAVYQAV 273


>UniRef50_C7LRJ9 CoA-binding domain protein n=1 Tax=Desulfomicrobium baculatum DSM
           4028 RepID=C7LRJ9_DESBD
          Length = 697

 Score = 71.6 bits (174), Expect = 7e-11,   Method: Composition-based stats.
 Identities = 81/466 (17%), Positives = 147/466 (31%), Gaps = 77/466 (16%)

Query: 66  VAIRSEAADAGI-AQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
           +A+      AG  A+ ++  LE    Q    S +  +    R    A   L   +LA++ 
Sbjct: 15  IAVVGSFDSAGALARVVLSNLEGWGYQGRIVSVNWTSQKDPR----ALDDLKGVDLAVVC 70

Query: 125 VAGEYAAELANQALDRNLNVMMFS-------DNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           +A E+  E   Q  D  +  ++ +              E  +   A  + L ++GP+C  
Sbjct: 71  LAPEFVLEALEQVADMGVKAVIITSAGFREIGGQGYYLEESIIQLAERRNLTLLGPNCLG 130

Query: 178 SMIAGTPLAFANVMP---EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSRE 234
                  L  + +     +GNI     SG+    +    A    G +    LG R +  E
Sbjct: 131 VASWADHLNASLIARLPSQGNIAFFSPSGSMCNAILDWAASEEIGFSKFASLGNRAVIDE 190

Query: 235 VGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT---- 290
                  + L+ L+ D ++ V+    +      R   ++      KP + L  G T    
Sbjct: 191 ------ASMLQFLAEDPQTSVIIGYLEGMNNGRRFARISQTITHEKPVIMLQAGMTEHGQ 244

Query: 291 -----------------PAVARDENVWFASSLD---EAARLACLLSRVTARRNAIAPVSS 330
                                +   +    +L    + AR+            AI   S 
Sbjct: 245 KAISSHVGALTGSERAYQTALKQAGIIQVDNLSSLFDLARMFGTQPLPKGPNLAIVTNSG 304

Query: 331 GFICGLYTGGTLAAEAA---GLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGR 387
           G        G LAA+      L+   LG +        +   A +  ++D+G D      
Sbjct: 305 GA-------GILAADGMAGTSLILPRLGRDTAARLVDILPRHAQTSNLVDIGMDA----- 352

Query: 388 PHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQP 447
                 P    Q +  +    Q+++ LL +  G G         + A  +   A      
Sbjct: 353 -----TPVQYAQALDTVLKDRQIQMALLVIAPGLGVD-------LPAIVRELVALPRAVG 400

Query: 448 LYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
                 + G E       ++   L+  G     S P+A L +   +
Sbjct: 401 KAVAVCLIGQE----GVMEEKRFLQRHG-LPCYSNPKAALASFEAM 441


>UniRef50_A0LDT0 CoA-binding domain protein n=6 Tax=Proteobacteria
           RepID=A0LDT0_MAGSM
          Length = 916

 Score = 71.6 bits (174), Expect = 7e-11,   Method: Composition-based stats.
 Identities = 37/214 (17%), Positives = 79/214 (36%), Gaps = 25/214 (11%)

Query: 91  QLAQGSGSSQALTQVRRWDSACQKLPDA---NLALISVAGEYAAELANQALDRNLN---V 144
               GS        +  + +  + +      N A++ V      +   +A+  + N   V
Sbjct: 74  PGRSGSTLKTPAGDIPVYSNVLEAVEAGHVFNAAVVYVPPSGVKDAVIEAVRVSPNLKKV 133

Query: 145 MMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTS------MIAGTPLAFAN---VMPEGN 195
           ++ ++ V ++D   ++   + +G+ V+G +C         +  G  L  AN    +  G+
Sbjct: 134 VILTEKVAVKDARIIRAYCQMRGVDVLGANCLGVADAHNKVRIGGALGGANPEESLIPGS 193

Query: 196 IGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEV 255
           + +   SG     +   +A AG G T ++  G +D+           A+     D++++ 
Sbjct: 194 VSIFSNSGNFTTTIAVYLATAGWGTTTSVSSG-KDVYIHYAAPEYTYAMH---NDDRTKA 249

Query: 256 LAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
             F  +P                 KP VA  +G 
Sbjct: 250 AVFYVEPGG------YYEHDLVFKKPVVACVVGR 277


>UniRef50_B1L7G3 Acyl-CoA synthetase (NDP forming) n=1 Tax=Candidatus Korarchaeum
           cryptofilum OPF8 RepID=B1L7G3_KORCO
          Length = 459

 Score = 71.2 bits (173), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 44/194 (22%), Positives = 80/194 (41%), Gaps = 19/194 (9%)

Query: 110 SACQKLPDA-NLALISVAGEYAAELANQALDRNLN-VMMFSDNVT----LEDEIQLKTRA 163
            +   +P++ +L +++V  +    +  +A D+     ++ S   +     E E +L   A
Sbjct: 58  KSISDIPESVDLVVVAVRADATPAVIEEAADKGARGALVISGGFSEVGNWELERKLVEVA 117

Query: 164 REKGLLVMGPDCGTSMIAGTPLA----FANVMPE---GNIGVIGASGTGIQELCSQIALA 216
           R++G+ V+GP+C         +        V+P    G I VI  SG+    + + +   
Sbjct: 118 RKRGIRVIGPNCLGIFDPKDKIDTLFLPERVIPRPGEGKIAVITQSGSLGSTVLTMMRKE 177

Query: 217 GEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMK 276
           G GI+  +  G R    E         LE L  DE ++V+A   +  A+  +        
Sbjct: 178 GMGISKFVSYGNRADVDEG------ELLEYLMEDEDTQVIAAYIESVADGRKFMESMRRA 231

Query: 277 ATGKPTVALFLGYT 290
           +  KP V L  G T
Sbjct: 232 SRRKPVVVLKGGKT 245


>UniRef50_Q1N4R6 Acyl-CoA synthetase (NDP forming) n=1 Tax=Bermanella marisrubri
           RepID=Q1N4R6_9GAMM
          Length = 910

 Score = 71.2 bits (173), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 43/252 (17%), Positives = 92/252 (36%), Gaps = 21/252 (8%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQL---AQGSGSSQALTQVRRWDSACQKLPDANLA 121
           +A+   +        A++Q L+ A  +    A      + +  V       +   D +LA
Sbjct: 15  IAVIGASEKTTSMGGAVIQNLKSAGFKGSVYAVNIRRYKTVHGVPCVSKIGRLPKDIDLA 74

Query: 122 LISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQ-------LKTRAREKGLLVMGP 173
           +I        ++  Q     ++ V++ +  ++ +   Q       L+  +RE  + +MGP
Sbjct: 75  IICTPAPTIEKIIKQLGKIGIHAVIILTGGISRKRAEQFRPSKNPLRQLSREYDVRIMGP 134

Query: 174 DCGTSMIAGTPLAFANVM---PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
           DC   +I    L  +        G +  +G SGT    L       G G +H + +G   
Sbjct: 135 DCLGLLIPDLKLNASYSHIQALPGKVAYLGQSGTLASALLDWAHGRGIGFSHFLTIG--- 191

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
              +   ++   A++ LS+  + + +    +   +A          +  K  +A+  G  
Sbjct: 192 ---DSADVAMPDAIDYLSSQRQVKAIMLHLEQVHDAKAFVRAVRNASRSKLVLAIKSGRF 248

Query: 291 PAVARDENVWFA 302
           P      ++  A
Sbjct: 249 PQSQSPVDLIPA 260


>UniRef50_UPI0001BCDEDD succinyl-CoA synthetase, alpha subunit n=1 Tax=Campylobacter fetus
           subsp. venerealis str. Azul-94 RepID=UPI0001BCDEDD
          Length = 153

 Score = 70.9 bits (172), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 33/144 (22%), Positives = 54/144 (37%), Gaps = 8/144 (5%)

Query: 196 IGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEV 255
           IG+I  SG+   E  +QI  AG GI+ A+G+G       V G++    L M      +  
Sbjct: 13  IGLISKSGSLTYEGANQILSAGYGISTAVGIG----VDSVIGLTYSELLPMFENGPDATA 68

Query: 256 LAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVAR---DENVWFASSLDEAARLA 312
           +  + +    ++ ++  + +K   KP VA   G +    +         +     AA   
Sbjct: 69  IVMIGEIGG-SLGIEACSIIKNMKKPVVAFIAGQSAPKGKRMGHAGAIISGEDSSAAGKM 127

Query: 313 CLLSRVTARRNAIAPVSSGFICGL 336
             LS   A   A        I  L
Sbjct: 128 KALSAAGAHVVASPAHIGKKIKEL 151


>UniRef50_C1XWJ3 Acyl-CoA synthetase (NDP forming) n=2 Tax=Meiothermus
           RepID=C1XWJ3_9DEIN
          Length = 775

 Score = 70.9 bits (172), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 75/370 (20%), Positives = 126/370 (34%), Gaps = 50/370 (13%)

Query: 75  AGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELA 134
           AG    +     +     AQ +G    +  +  + S        +LA+I+V  +     A
Sbjct: 237 AGPVYPVNPAASQVTAGSAQANGEVLVVGSILAYPSVKAIPGPVDLAVITVPPDQVIAAA 296

Query: 135 NQALDRNLN-VMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPL----AFAN 189
                R +  +++ +  +       L    R  G+ ++GP     +     +      A 
Sbjct: 297 ESCGQRGVRALVVVTVGLCAGQIKSLGEVCRSYGMRLVGPGSLGLVHTHPEVRLAAGLAG 356

Query: 190 VMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSA 249
           + P G + +   SG     +       G GI+  + LG +        +S+   ++    
Sbjct: 357 MPPRGRLALSSQSGALGLAVLEYAREMGLGISSFVSLGAK------ADVSSNDLIQFWED 410

Query: 250 DEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVA---RDENVWFASSLD 306
           D ++ V+    +      R   +       KP + +  G  P V    +   V  A SL+
Sbjct: 411 DPETGVILLYIENFGNPRRFARLARRVGRQKPILVVRPGRDPRVEALFQQTGVIRADSLE 470

Query: 307 EAARLACLLSRVTARRNAIAPVSSGFICGLYTG-GTLAAEAAGLLAGHLGVEADDTHQHG 365
           E    A LL+           + S       +G GTLA EA        G+EA       
Sbjct: 471 EVFDTAALLTFQPLPAGPRVALVSNA-----SGPGTLALEAL----RSGGLEA------- 514

Query: 366 MMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQV-RVLLLDVVIGFGAT 424
                      DLG              P+   + IA L A P    V++L V +GF  T
Sbjct: 515 --------THFDLGSTA----------TPSQYRETIAQLLADPAYDAVMVLFVPMGFAPT 556

Query: 425 ADPAASLVSA 434
            D AA+L  A
Sbjct: 557 EDVAAALAEA 566


>UniRef50_Q2JX06 Acetyltransferase, GNAT family n=25 Tax=Bacteria RepID=Q2JX06_SYNJA
          Length = 931

 Score = 70.5 bits (171), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 83/440 (18%), Positives = 143/440 (32%), Gaps = 70/440 (15%)

Query: 112 CQKLPD-ANLALISVAGEYAAELANQALDRNLN-VMMFSDNVT------LEDEIQLKTRA 163
              LP+  +LA+I++       +  + ++  +   ++ S          LE E  ++  A
Sbjct: 76  LSALPEPVDLAIIAIPAAGVPAVIQECVEAGVKGAIVLSAGFKEIGPEGLELEKAIQEAA 135

Query: 164 REKGLLVMGPDCGTSMIAGTPL--AFANVM-PEGNIGVIGASGTGIQELCSQIALAGEGI 220
           R K L ++GP+C       T L   FA  M   GN+G I  SG     +         G 
Sbjct: 136 RGK-LRLIGPNCLGIQNPHTGLNATFAAQMARPGNVGFISQSGALCTSILDWSLQENVGF 194

Query: 221 THAIGLGGRDLSREVGGISALTA-----LEMLSADEKSEVLAFVSKPPAEAVRLKIVNAM 275
           +  I LG           S L       ++ L  D  +  +    +   +A         
Sbjct: 195 SAFISLG-----------SMLDVGWGDLIDYLGQDPHTHSIVLYMESVGDARSFLSAARE 243

Query: 276 KATGKPTVALFLGYT-----PAVARDENVWFASSLDEAARLAC------------LLSRV 318
            A  KP + +  G T      A +   ++  + ++ +AA   C             ++ V
Sbjct: 244 VALSKPIIVIKAGRTQAAAQAAASHTGSLTGSDAVLDAAFRRCGVLRVDHIEDLFDMAEV 303

Query: 319 TARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHL-GVEADDTHQHGMMLD---ADSHQ 374
            A++          +      G LA +A     G L  +  +   Q   +L    +  + 
Sbjct: 304 LAKQPRPQGPHLSILTNAGGPGVLATDALIRAGGSLASLAPETLEQLSQILPPHWSHGNP 363

Query: 375 IIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSA 434
           I  LGD             P    Q +  +   P  +  L  V++   A  DP A+    
Sbjct: 364 IDVLGDAG-----------PERFAQALEIVLRDPGSQGCL--VILTPQAMTDPTATAAKV 410

Query: 435 WQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH 494
            +     R        +A+  G              L  AGI       +A  + + L  
Sbjct: 411 VE---TWRRSGSRQPILASWMGGAL----VDAGEQILNQAGIPTYRYPDQAARVFSYLWR 463

Query: 495 -PLSPAAQQHTPSLLENVAV 513
              +  A   TP+L    AV
Sbjct: 464 FSDNLKALYETPTLPPARAV 483


>UniRef50_Q47QC9 Probable 6-carboxyhexanoate--COA ligase n=1 Tax=Thermobifida fusca
           YX RepID=Q47QC9_THEFY
          Length = 692

 Score = 70.1 bits (170), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 94/480 (19%), Positives = 158/480 (32%), Gaps = 67/480 (13%)

Query: 110 SACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVT------LEDEIQLKTR 162
           SA       + A + V            L+R +  V + S           E + +L  R
Sbjct: 61  SARDLPEQVDAAYLLVPARAVESALEDCLERGIRTVTICSAGYAELGAEGAERQRRLVER 120

Query: 163 AREKGLLVMGPDCGTSM------IAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALA 216
           ARE+G+ ++GP+C   +      +             G+I ++  SG     L ++    
Sbjct: 121 ARERGVRILGPNCIGVLNPVDTYVGCPTFNITYSYTPGSIALLSQSGGMAAALFNRAQGR 180

Query: 217 GEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAF-VSKPPAEAVRLKIVNAM 275
             GI   + LG          I     L+   AD ++ V+A  + +              
Sbjct: 181 TIGIRTMVSLGNE------ADIQMGELLDAFVADPQTRVIAIYIEQLRDAERFAAAAERA 234

Query: 276 KATGKPTVALFLGYTPA---------------------VARDENVWFASSLDEAARLACL 314
           +A GKP V L +G + A                     + R   V    S+D+    A  
Sbjct: 235 RAAGKPIVLLKVGGSEAGRRTVLGHTGAMAGEQAVFSSMMRHLGVVEVHSIDDLLNTAYA 294

Query: 315 LSRVTARR-NAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSH 373
           LS +       +  +S        +GG     A    A   G+E     Q  +   ++  
Sbjct: 295 LSSLPLPAGPRLGALSP-------SGGECGYIADR--ASAHGLEIPLPTQQTLDELSEKL 345

Query: 374 QIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVS 433
           ++   G+   T G+   + D  L ++L+    A P + ++ L +   +G     A  L+ 
Sbjct: 346 KLARPGNPLDTTGQV--IGDGALLSELMQIFTADPNLDMITLSIPT-WGPYDSNA--LLP 400

Query: 434 AWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
               A  A      L A      TE       +    L ++GI   +S  EA    A L 
Sbjct: 401 RIIDAVKACDKPAVLSAWTARNLTE-------RAEELLRESGICWFASSDEAIAALANLR 453

Query: 494 H----PLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLAR 549
                  +P+A    P  L    V  +   +    L     PVV    +P      + AR
Sbjct: 454 RYAELAQAPSATPPEPVSLPRPEVTELNEYAAKRLLAEGGVPVVAETLAPDTEAALRAAR 513


>UniRef50_C9R913 Acetyl coenzyme A synthetase (ADP forming), alpha domain protein
           n=2 Tax=Clostridia RepID=C9R913_AMMDK
          Length = 699

 Score = 70.1 bits (170), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 44/223 (19%), Positives = 82/223 (36%), Gaps = 21/223 (9%)

Query: 88  ALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMF 147
            +   A      +A   V             +LA+++V   +  ++A    +  +  ++ 
Sbjct: 42  PINPRAGEIEGLKAFPAVSALGR-----GAVDLAVVAVPAPFVLDVARDCGEAGVKALVV 96

Query: 148 -------SDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPL--AFANVMP-EGNIG 197
                  +    LE E +L    R+ G+ ++GP+C   M   TPL  +FA   P +G I 
Sbjct: 97  ISAGFKETGKEGLEREKELVAICRQYGMRLLGPNCVGVMDTHTPLNASFAAGFPHKGEIA 156

Query: 198 VIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLA 257
            I  SG  +  +       G G +  + +G +        +     +E  + D  ++V+ 
Sbjct: 157 FISQSGAMLVAILDWSMREGIGFSQFVSMGNK------ADLDETDLIEAAANDPHTKVIL 210

Query: 258 FVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
              +   E  R   V       KP V L  G + A A+  +  
Sbjct: 211 CYLEDIKEGQRFLEVAERVTREKPVVVLKSGVSEAGAKAASSH 253


>UniRef50_A2SEI4 Acyl-CoA synthetase (ADP forming) n=13 Tax=Burkholderiales
           RepID=A2SEI4_METPP
          Length = 918

 Score = 69.7 bits (169), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 46/264 (17%), Positives = 87/264 (32%), Gaps = 11/264 (4%)

Query: 65  CVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
            + +     D        + L +AL+     +G+ Q L        A      A+LA+I+
Sbjct: 37  IIVLAGAPDDPTGQTPQARVLHQALRAQPY-AGALQFLDIHATGTLAELAQTRADLAVIA 95

Query: 125 VAGEYAAELANQALD-RNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGT 183
           +  +  A     A      + ++ S  +  E    LK  A+ +G+ ++GP+         
Sbjct: 96  LPPQQVASALEVAGRLACRSALVVSSGIGAEAAATLKKIAQREGIHLLGPNGLGFQRPAL 155

Query: 184 PL---AFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            L   A   +   G++ ++  SG     +    +    G +  + LG          +  
Sbjct: 156 QLNASAAGPLAKPGSLALVSQSGALTTSVLDWASTNAVGFSSVVSLG------PNTSVDI 209

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
              L+ L+ D ++  +    +  + A          A  KP V L  G  PA        
Sbjct: 210 AQVLDYLANDAQTHSIVVYVEGISSARHFMSALRSAAKAKPVVVLKAGRKPAGNEAAQTH 269

Query: 301 FASSLDEAARLACLLSRVTARRNA 324
             + +         L R  A R  
Sbjct: 270 SGAIVGSDDVFDAALRRAGAVRVR 293


>UniRef50_Q2NFU6 Predicted acyl-CoA synthetase n=4 Tax=Methanobacteriaceae
           RepID=Q2NFU6_METST
          Length = 700

 Score = 69.7 bits (169), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 44/220 (20%), Positives = 90/220 (40%), Gaps = 22/220 (10%)

Query: 118 ANLALISVAGEYAAELANQALDRNL-NVMMFS--------DNVTLEDEIQLKTRAREKGL 168
            +LA+IS+   +  +   +   + + N+++ +        +   LEDE+     A++  +
Sbjct: 70  IDLAVISIPARFINQTLEECGQKGIKNIIVITAGFKEVGGEGAKLEDEMA--EIAKKYDM 127

Query: 169 LVMGPDCGTSMIAGTPL--AFANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIG 225
            + GP+C  S+   TP+  +FA + P+ GNI  +  SG     +       G G +  + 
Sbjct: 128 NIQGPNCLGSLDTNTPMNASFAQLSPKKGNIAFVSQSGAMTVAILDWSVSEGIGFSKVVS 187

Query: 226 LGGR-DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
           LG + D+S        +  +E L+ D++++V+    +  ++  R   V       KP V 
Sbjct: 188 LGNKVDVSE-------IDLIEYLATDDQTKVILCYLEGISDGERFLEVMRRVTKIKPVVI 240

Query: 285 LFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNA 324
           L  G + A A+  +    +     +            R  
Sbjct: 241 LKAGSSQAGAKAVSSHTGALAGNDSAFDAAFENCGVMRAR 280


>UniRef50_D2LIT8 CoA-binding domain protein n=1 Tax=Rhodomicrobium vannielii ATCC
           17100 RepID=D2LIT8_RHOVA
          Length = 911

 Score = 69.7 bits (169), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 76/417 (18%), Positives = 137/417 (32%), Gaps = 87/417 (20%)

Query: 85  LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDA-----NLALISVAGEYAAELANQALD 139
            E  LK    G  +     +       C K  DA      LA+++   E    +  +   
Sbjct: 32  AENLLKGGFTGDIAFINPKRPAILGQPCFKSVDALPFTPGLAVVATPPETVPGVIEELGR 91

Query: 140 RNLNV-MMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPL--AFANVM-PEGN 195
           +     ++ +  V+ +   ++   AR   L ++GP+C    +    L  +FA V+   G+
Sbjct: 92  KGCRAAVVITAGVSGDLRKRMLEAARPHLLRIIGPNCLGMQVPRLGLDASFAQVLGKAGS 151

Query: 196 IGVIGASGTGIQELCSQIALA---GEGITHAIGLGGRDLSREVGGISALTALEMLSADEK 252
           + ++  SG       + +  A   G G +H + +G      +   +     L+ L+ +  
Sbjct: 152 VALVSQSGAIT---TAMLDWASVEGVGFSHVVSIG------DAADVDLGDMLDYLAGETT 202

Query: 253 SEVLAFVSKPPAEAVRLKIVNAMKATG--KPTVALFLGYTP------------------- 291
           S  +    +   +    K ++A +     KP +A+  G  P                   
Sbjct: 203 SRAVFLYIESVGD--ARKFMSAARRCARVKPVIAIKAGRHPEGAKAAASHTGALAGSDNV 260

Query: 292 --AVARDENVWFASSLD---EAARLACLLSRVTARRNAIAPVSSGF----------ICGL 336
             A  R   V   + LD   +AA +   +  +   R AI     G             G 
Sbjct: 261 YGAALRRAGVLRVTDLDAMFDAAEMLAYVPAMPGDRVAIVTNGGGAGVLAVDSLTDFRGT 320

Query: 337 YTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTL 396
               TLA E        L      T   G  +D       D G D Y             
Sbjct: 321 LA--TLAPETI----DALDAALPTTWSRGNPVDIIG----DAGPDRY------------- 357

Query: 397 RNQLIADLGAKPQV-RVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIA 452
               +  + A P    VL+++      ++ D A ++V+A Q+    R   +    IA
Sbjct: 358 -RATLDAVLADPNADAVLVMNCPTALASSLDGAKAVVAAVQEM---RAKGRNKPVIA 410


>UniRef50_A4YGK5 CoA-binding domain protein n=15 Tax=Archaea RepID=A4YGK5_METS5
          Length = 660

 Score = 68.9 bits (167), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 69/455 (15%), Positives = 157/455 (34%), Gaps = 64/455 (14%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN--VMMFSDNVTLED 155
            S+ +  V+ + S      D +LA+ISV  E    +  +A ++ +   +++ S    + +
Sbjct: 46  KSETIEGVQSYKSLKDIQDDVDLAIISVPRESVPGVMEEAGEKGVRSAIVITSGFREVGE 105

Query: 156 E-----IQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANV-MPEGNIGVIGASGTGIQEL 209
           E      ++ + A + G+  +GP+    +       FA   +  G I ++  SG     +
Sbjct: 106 EGEKLEREVASIANKYGIRFLGPNTMGLLTPDYNGTFAFADVKRGEIALVVQSGGIGAYM 165

Query: 210 CSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRL 269
            +    +  G++  + LG +   +E         ++ L+ D +++ +    +  ++  + 
Sbjct: 166 LNWAQKSRTGVSFLVSLGNQTDVKEY------EVIDYLAKDPETKAIFVYIEGVSDGEKF 219

Query: 270 KIVNAMKATGKPTVALFLGYTPAVARD-----ENVWFASSLDEAARLAC---------LL 315
             V     + KP + +  G +   A        ++  +  + +AA               
Sbjct: 220 LNVVPEATSRKPVIFIKGGASAQSAEAVKTHTGSLAGSYEVFKAAIKTVGGIFVENLKDF 279

Query: 316 SRVTARRNAIAPVSSGFICGLYTG--GTLAAEA---AGLLAGHLGVEADDTHQHGMMLDA 370
             ++   N+  P+    +    +G  G L ++A   AGL    +    +   +  +   +
Sbjct: 280 LNLSKLVNSSEPIREEILVVTNSGGHGVLTSDAISRAGLSLVKIPERLNMELRKVLPPQS 339

Query: 371 DSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAAS 430
                +DL  D    GR     D  L +  I       ++ ++                 
Sbjct: 340 IPKNPLDLSGDA---GR-----DRYLNSLKIVSDLDCTKLVIV----------------E 375

Query: 431 LVSAWQ--KACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLL 488
            +      +     L+ +    I    G + D          LE A I V +   EA   
Sbjct: 376 SLPFISCTEVAKVLLNFKGKGIIGVTMGYDED-----SASRILESASIPVFTFPEEAVNA 430

Query: 489 AAALIHPLSPAAQQHTPSLLENVAVINIGLRSFAL 523
            + L+   SP  +      +++   ++ G    A 
Sbjct: 431 ISKLVKRPSPRRKVRVTQPIDSARELSKGKSFLAD 465


>UniRef50_Q2BN19 Acetyltransferase, GNAT family protein n=1 Tax=Neptuniibacter
           caesariensis RepID=Q2BN19_9GAMM
          Length = 914

 Score = 68.9 bits (167), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 69/391 (17%), Positives = 144/391 (36%), Gaps = 61/391 (15%)

Query: 65  CVAIRSEAADAGIAQAI-MQQLEEALKQLAQGSGSSQALTQVRRWD--SACQKLPDA-NL 120
           C+A+   +        + +Q L+E+  + +  + +SQ   QV           LP+  +L
Sbjct: 14  CIAVFGASEKENSMGGVVIQNLQESGFKGSLYAVNSQGYEQVHGVSCFKRLSDLPEMPDL 73

Query: 121 ALISVAGEYAAELANQALDRNL--NVMMFSDNVTLED-------EIQLKTRAREKGLLVM 171
           A+I    E  A+   + L  ++    M+ +  +++ D         ++K  A+  G+ ++
Sbjct: 74  AIICSPPESVAD-IIRGLGASMVKAAMILTGGLSIADGDSSQTLRDEVKEAAKPYGIRIL 132

Query: 172 GPDCGTSMIAG--TPLAFANV-MPEGNIGVIGASGTGIQELCSQIALAGE---GITHAIG 225
           GPDC   ++ G     ++++V + +G +  +G SG       + I  A     G +H + 
Sbjct: 133 GPDCMGLLVPGHNMNASYSHVNILKGKVAYVGQSGILG---TAMIDWATGQEIGFSHFLT 189

Query: 226 LG-GRDLSREVGGISALTALEMLSADEKSEVLAF-VSKPPAEAVRLKIVNAMKATGKPTV 283
           LG G D+          + ++ L+ D  +  +   +++    A          +  K  +
Sbjct: 190 LGDGADV-------DMPSVIDYLAQDPYTHAILLQLNRVDGSARDFLSAVRSASRNKLVL 242

Query: 284 A----LFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSS----GFICG 335
                 F+G          +     + +AA     + RV         + +      + G
Sbjct: 243 VLKNDTFVGEKSGTELAPGIHDDDQVYDAALRRAGVVRVETSDELFNALETLTRMKPMRG 302

Query: 336 ----LYTGGT----LAAEAAGLLAGHLGVEADDTH-QHGMMLDADSHQI--IDLGDDFYT 384
               + + GT    LA E      G L    +D+  Q   +L +  ++   +DL  D   
Sbjct: 303 ERLAILSNGTGPNALATEKLLEQGGQLAKLTEDSIAQLSEILPSHWNRSNPVDLNADA-- 360

Query: 385 VGRPHPMIDPTLRNQLIADLGAKPQVRVLLL 415
                   DP    + +  L     V  +L+
Sbjct: 361 --------DPARFAEAVRILTKDKNVDAVLM 383


>UniRef50_B6YUE1 Acyl-CoA synthetase (NDP forming), large subunit n=2
           Tax=Thermococcus RepID=B6YUE1_THEON
          Length = 438

 Score = 68.9 bits (167), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 46/282 (16%), Positives = 95/282 (33%), Gaps = 24/282 (8%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQL---AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VAI     +  IA  I++ + E                     + ++   +     + A+
Sbjct: 10  VAIFGSFKEGAIAYEILRNIVEGGFDGRIVPVNPKGGTVEIAGKAFEIRPKLEEPVDAAI 69

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVT----LEDEIQLKTRAREKGLLVMGPDCGTS 178
           I++  ++   L ++  +     ++ S   +    +E E +L  +AR+ G+ ++GP+C   
Sbjct: 70  IAIPAKFVPSLIDEIGELIKGAVVISAGFSEVGNVELERELVEKARKHGIRIIGPNCAGI 129

Query: 179 -MIAGTPLA-FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLG-GRDLSREV 235
             + G     F   +  G + +I  SG       +       G +  +  G   DL+   
Sbjct: 130 FGVHGKFFGSFEVRVKPGGLALISQSGAFGGAALAMGNDERIGFSAFVSYGNAADLNES- 188

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVAR 295
                   L   + D+ ++ +A   +   +  R        A  KP + L  G + + AR
Sbjct: 189 ------DFLRYFADDKNTKAIALYIEGVRDGRRFMEALRYAAGKKPVIILKAGKSKSGAR 242

Query: 296 DENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLY 337
                          LA       A       +    + GL+
Sbjct: 243 AAASH-------TGSLAGSYEIYRAAFKQAGAIEVEEMEGLF 277


>UniRef50_A2BLI1 Universally conserved protein n=1 Tax=Hyperthermus butylicus DSM
           5456 RepID=A2BLI1_HYPBU
          Length = 476

 Score = 68.9 bits (167), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 38/203 (18%), Positives = 78/203 (38%), Gaps = 22/203 (10%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNV----- 151
           ++  +  ++ + +        +LA+++V  +   ++ +QA  R +  V++ S        
Sbjct: 55  NADEILGLKAYPTIMDVPDPVDLAVVTVPAKMVPDVVDQAGRRGVRAVIVISAGFREVGG 114

Query: 152 -TLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLA-------FANVMPEGNIGVIGASG 203
             +E E +L    R+ G+ ++GP+C       T +           +  +G I  I  SG
Sbjct: 115 EGVELEKRLLEVVRKHGIRMLGPNCLGVYSPSTGINATFLDPEKQGLPGKGPIAFISQSG 174

Query: 204 TGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPP 263
                L   +     GI+  I +G +    E         L  L  D +++ +A   +  
Sbjct: 175 ALGAALLDWLDANQFGISKFISIGNKADIDE------ADLLAYLRKDPETKSIAMYIEGV 228

Query: 264 AEAVRLKIVNAMKATG--KPTVA 284
           A     +   A++ T   KP V 
Sbjct: 229 APGEGGRFRRALEETTHEKPVVI 251


>UniRef50_A1U3K8 GCN5-related N-acetyltransferase n=4 Tax=Gammaproteobacteria
           RepID=A1U3K8_MARAV
          Length = 915

 Score = 68.5 bits (166), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 56/345 (16%), Positives = 113/345 (32%), Gaps = 37/345 (10%)

Query: 97  GSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLED 155
              + +  V       +     +LA+I    +   ++  +  +  +   ++ +  ++   
Sbjct: 50  SDYENVHGVPCVRKVSKLDFSPDLAIICTPPDTVPKMIRKLGECGVRTAIVMTGGMSRTH 109

Query: 156 -------EIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMP---EGNIGVIGASGTG 205
                     ++  ARE G+ V+GP+    M+    L           G +  +G SGT 
Sbjct: 110 SKTGQPLMYSVRDAARETGIRVLGPNTIGLMVPARHLNATYAHMGAIPGRVAFVGQSGTI 169

Query: 206 IQELCSQIALAGEGITHAIGLG-GRDLSREVGGISALTALEMLSADEKSEVLAF-VSKPP 263
              +       G G ++ + LG G D+            ++ L+ D ++  +   +   P
Sbjct: 170 ASSVLDWAFARGVGFSYFLTLGDGMDI-------DHDDLIDYLAQDTQTRAILLHIENIP 222

Query: 264 AEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRN 323
               R      + +  KP +A+  G  P      +   A           +L R    R 
Sbjct: 223 NPR-RFMSAVRVASRTKPVIAVKSGRVPESEWFTHALPAGIKRSDPVYDAMLQRAGVLRV 281

Query: 324 AIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGV----EADDTHQHGMMLDADSHQIIDLG 379
                    +  L     L  E+  ++A  +G             G + +     + +LG
Sbjct: 282 DGLGQMFDALETLTRMRPLRRESLAIMANGVGPGVLAVDRLADLGGELAELSEDTVRELG 341

Query: 380 D---DFYTVGRPHPMID------PTLRNQLIADLGAKPQVRVLLL 415
           +    ++T   P   ID      P L  + I  L   P V  +L+
Sbjct: 342 ELLPPYWTRKNP---IDLNYDATPELYGKAIKILAKDPNVANVLV 383


>UniRef50_Q02CE8 CoA-binding domain protein n=2 Tax=Bacteria RepID=Q02CE8_SOLUE
          Length = 703

 Score = 68.5 bits (166), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 86/446 (19%), Positives = 143/446 (32%), Gaps = 62/446 (13%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNL-NVMMFSDNVTLEDE 156
              A+T      S  Q     + A++++              R +   ++FS       E
Sbjct: 56  KYPAITGRPCLPSPDQLPQGVDCAVLAIPRAGVLNALEGCARRGVGAAIVFSAGYAESGE 115

Query: 157 I------QLKTRAREKGLLVMGPDCGTSM--IAGTPLAFANVMPEGN-----IGVIGASG 203
                  Q++  AR  G++V GP+C   +  I GTPL F    P        + +I  SG
Sbjct: 116 AGRAEQDQIREIARRSGMVVEGPNCLGMVNAIDGTPLTFVASNPAKPRPGRTLALISQSG 175

Query: 204 TGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPP 263
                L   +   G  I+ +I  G    +  V G+     LE L  D  + V+  V +  
Sbjct: 176 ALAAVLGVSLRERGLDISFSISSG----NEAVAGV--EDFLEYLIEDPATMVITLVVEQF 229

Query: 264 AEAVRL-KIVNAMKATGKPTVALFLGYTP---------------------AVARDENVWF 301
            + +R   +    +  GK    L  G +                         R   V  
Sbjct: 230 RDPMRFLDLAERARTCGKRLALLHPGSSSAARASAATHTGAMAGDYQVMRTKVRQAGVLM 289

Query: 302 ASSLDEAARLACLLSRVTARRNAIAPV--SSGFICGLYTGGTLAAEAAGLLAGHLGVEAD 359
            S+L+E   +  +L R      A   V   SGF   L     L  E    L        +
Sbjct: 290 VSTLEELIDVTEILVRCPTLPRAGTAVFTESGFFKALTL--DLCEELGVPLPPLADATHE 347

Query: 360 DTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVI 419
              Q        S+ +     D    G    ++DP L  + +  + A  +   ++L +++
Sbjct: 348 ALRQALPDFIPPSNPL-----DITAQG----LVDPGLYRRTLPPVLADERYGCVVLSIIL 398

Query: 420 GFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVV 479
              + A+ A   +     A       +P+       G    PQ   +Q   L DAG    
Sbjct: 399 ---SEAETAGLKIPPIIAALREIHAEKPVLFACMDEGAPI-PQAYIEQ---LRDAGAPYF 451

Query: 480 SSLPEATLLAAALIHPLSPAAQQHTP 505
            S        AA+    +    +  P
Sbjct: 452 PSAERTFRALAAVSQSQAEPECEERP 477


>UniRef50_C8S7L3 CoA-binding domain protein n=1 Tax=Ferroglobus placidus DSM 10642
           RepID=C8S7L3_FERPL
          Length = 459

 Score = 68.5 bits (166), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 35/203 (17%), Positives = 74/203 (36%), Gaps = 27/203 (13%)

Query: 104 QVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMF----------SDNVTL 153
            V+ + S        +LA+++V  +       + L++     +           +D   L
Sbjct: 55  GVKAYRSVKDLPETPDLAILAVPRDAIYNSVRELLEKGCRAFVIISAGFREAEIADGEEL 114

Query: 154 EDEIQLKTRAREKGLLVMGPDCGTSM-----IAGTPLAFANVMPEGNIGVIGASGTGIQE 208
               +LK        +V+GP+    +     +  +     +++ +G+I +I  SG     
Sbjct: 115 HK--KLKELVDSYNAVVIGPNTFGMVNLKADLNASFTPALSLLKKGDIALISQSGGVCHL 172

Query: 209 LCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVR 268
           +       G G +  +GLG R        +     LE L  D++++ +A   +       
Sbjct: 173 IAPYSMREGIGFSKIVGLGNR------LNVDFHDMLEYLKDDKETKSIALYIE--GIDEP 224

Query: 269 LKIVNAMKATG--KPTVALFLGY 289
            K+   ++     KP VA+  G 
Sbjct: 225 KKLCEKIREVSRVKPVVAMKAGR 247


>UniRef50_UPI0001B56A88 CoA-binding domain protein n=1 Tax=Streptomyces sp. AA4
           RepID=UPI0001B56A88
          Length = 947

 Score = 68.5 bits (166), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 73/461 (15%), Positives = 140/461 (30%), Gaps = 49/461 (10%)

Query: 65  CVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
            +   ++    G          +    +   +   +++  VR + S        +LAL++
Sbjct: 263 VIGASADPTKVGHVAFANLLAADFAGAVYPVNPEHRSVRGVRAYPSVLDIPDPVDLALVA 322

Query: 125 VAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           V  E    + +  L + +  ++        S  + L  E++L   AR  G+ V+GP+   
Sbjct: 323 VPAEAVESVLDACLAKGVKTLVIVSGGFAESGPLGLHAELRLVGEARAHGMRVVGPN-AL 381

Query: 178 SMIAGTPLAFANVM------PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
            ++        N          G  G    SG     + +     G G++  +  G R  
Sbjct: 382 GVLNTAKDVRLNATLAPRLPKRGRTGFFCQSGALGTAILADAGSRGLGLSTFVSAGNR-- 439

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
             +V G   L        D  ++++    +      +   +    A  KP VA       
Sbjct: 440 -ADVSGNDLLQ---YWETDPDTDLVLLYLESFGNPRKFARLARRLARSKPIVA------- 488

Query: 292 AVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLA 351
                           A       + V A       V    +  L+    + A       
Sbjct: 489 ---VKSGRHAVRPQLAATSAEVDEASVQALFEQAGVVRVESLAQLFDTALVFAHQPLPAG 545

Query: 352 GHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVR 411
             +G+  + +    +  D    + + L  D   +G   P   P      + +    P   
Sbjct: 546 PRIGIVGNSSAIGLLAADTARAEGLRLAFDPVDIG---PQAGPDEFATAVREALDSPDT- 601

Query: 412 VLLLDVVIGFGATAD--PAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIA 469
               D +I   A     P A+   A ++A +    ++P   ++T    E  P       A
Sbjct: 602 ----DALIAVFAPPVAIPGAAYARALREAVSEMKQSKP--IVSTFLAAEGVPDEL----A 651

Query: 470 TLEDAGIAV---VSSLPEATLLAAALIHPLSPAAQQHTPSL 507
            L D G+     + S         AL   +  AA +  P  
Sbjct: 652 VLSDDGVPTRGSIPSYSSPERAVNALARVVRYAAWRQRPQG 692


>UniRef50_D0MJL0 Acetyl coenzyme A synthetase (ADP forming), alpha domain protein
           n=6 Tax=Bacteria RepID=D0MJL0_RHOM4
          Length = 929

 Score = 68.5 bits (166), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 71/439 (16%), Positives = 139/439 (31%), Gaps = 69/439 (15%)

Query: 100 QALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN--VMMFSDNVTLEDEI 157
             +  +R + S        +LA+I+        +  + ++  +   V++ +    + +E 
Sbjct: 70  TNVLGIRAYPSVKDIPEPVDLAVIATPAPTVPGVVQECVEAGVKGAVIISAGFKEIGEEG 129

Query: 158 Q-----LKTRAREKGLLVMGPDCGTSM--IAGTPLAFANVM-PEGNIGVIGASGTGIQEL 209
           +     + T AR  G+ ++GP+C   M  + G    FA+ M   G +G I  SG  +  +
Sbjct: 130 RRLEEQILTIARRGGMRIIGPNCLGVMRPVTGLNATFASTMARPGTVGFISQSGALLTSI 189

Query: 210 CSQIALAGEGITHAIGLGGRDLSREVGGISALTA-----LEMLSADEKSEVLAFVSKPPA 264
                    G +  I +G           S L       +  L +D  ++ +    +   
Sbjct: 190 LDWSLEENVGFSAFISIG-----------SMLDVGWGDLIYYLGSDPYTKSIILYMESIG 238

Query: 265 EAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNA 324
           +A          A  KP + +  G T   AR       ++L     LA     ++A    
Sbjct: 239 DARSFLSAAREVALQKPIIVIKAGRTEEAAR-------AALSHTGSLAGSDEVLSAAFRR 291

Query: 325 IAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYT 384
              +    I  L+            +A  L  +         +L       + L  D   
Sbjct: 292 TGVLRVDSIADLF-----------YMAEVLAKQPRPEGPRLTILTNAGGAGV-LATDALV 339

Query: 385 VGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASL--------VSAWQ 436
            G              +A+L    + +  L + +    +  +P   L          A +
Sbjct: 340 QG-----------GGQLAELS--EETKKKLDEFLPPHWSHGNPVDILGDADPERYAKALE 386

Query: 437 KACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPL 496
              A    +  L  +     T  DP   ++Q+     +   +++S      +AA     L
Sbjct: 387 VTLADENSDGLLVILTPQAMT--DPTQTAEQLRRFAQSRKPILASWMGGVEVAAG-KKIL 443

Query: 497 SPAAQQHTPSLLENVAVIN 515
           + A           V V N
Sbjct: 444 NRAGIPTFQYPDTAVRVFN 462


>UniRef50_Q9UYT1 AcdA-4 acetate--coA ligase (ADP-forming), alpha chain n=3
           Tax=Pyrococcus RepID=Q9UYT1_PYRAB
          Length = 442

 Score = 68.2 bits (165), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 46/247 (18%), Positives = 92/247 (37%), Gaps = 21/247 (8%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQL---AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VAI     +  IA+ I++ + E   +                 RR++   +   + ++++
Sbjct: 10  VAIFGSFREGAIAREILRNIVEGGFEGKIIPVNPKGGTVEVAGRRFEIRKRLEEEVDVSI 69

Query: 123 ISVAGEYAAELANQA--LDRNLNVMM--FSD--NVTLEDEIQLKTRAREKGLLVMGPDCG 176
           + +  +    L  +   L +   V+   FS+  NV LE+E  L   A+E G+ ++GP+C 
Sbjct: 70  VVIPAKLVPGLIRELKGLTKGAVVISAGFSEVGNVDLEEE--LIKAAKEAGIRIIGPNCA 127

Query: 177 TS-MIAGTPLA-FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLG-GRDLSR 233
               + G     F   +  G + +I  SG       +       G +  +  G   DL  
Sbjct: 128 GIFGVHGKFFGSFEVRVNPGGLALISQSGAFGGAALAMGNEENVGFSAFVSYGNAADLDE 187

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAV 293
                     L   + DE ++V+A   +   +  +         + KP + L  G + + 
Sbjct: 188 S-------DFLRYFADDENTKVIALYIEGVKDGRKFFEALKYATSKKPVIILKAGKSESG 240

Query: 294 ARDENVW 300
           A+     
Sbjct: 241 AKAAQSH 247


>UniRef50_B9L969 CoA binding domain protein n=2 Tax=Epsilonproteobacteria
           RepID=B9L969_NAUPA
          Length = 634

 Score = 68.2 bits (165), Expect = 8e-10,   Method: Composition-based stats.
 Identities = 40/246 (16%), Positives = 89/246 (36%), Gaps = 29/246 (11%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDS----ACQKLPDANLA 121
           VAI             + +       L   +       ++++  S        LP  + A
Sbjct: 227 VAIIGATDKKEKVGYAIAK-----NALKSKAKIYFVNPKLKKLFSKKVYTLDTLPQVDTA 281

Query: 122 LISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPD 174
           +I++   Y  E   +   +     +        S N +   E++LK  A+E  + ++GP+
Sbjct: 282 VIAIPSVYVIESVKKLAKKGCKNFIIISAGFKESGNTSA--ELELKELAKEHNINIIGPN 339

Query: 175 CGTSMIAGTP--LAFA-NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
           C           L FA + +  G+IG++  SG  +  L  + +    G +H I +G    
Sbjct: 340 CLGIYNDTLKLNLTFAKSRIYSGSIGLVSQSGAVLTALLDKASHYKTGFSHIISMG---- 395

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
              +   +   A+  L+  +  + ++  ++        + + A++   KP +    G + 
Sbjct: 396 --NMADFNFAHAVNELNRQKNCKTISIYAE--GLQFGKEFLKAIRNLQKPVLLFKSGKSK 451

Query: 292 AVARDE 297
              +  
Sbjct: 452 EAKKAA 457


>UniRef50_C4PZV0 ATP-citrate synthase, putative n=1 Tax=Schistosoma mansoni
           RepID=C4PZV0_SCHMA
          Length = 1164

 Score = 68.2 bits (165), Expect = 8e-10,   Method: Composition-based stats.
 Identities = 36/234 (15%), Positives = 78/234 (33%), Gaps = 50/234 (21%)

Query: 102 LTQVRRWDSACQKLPDANLALISVAGEYAAELANQALD---------------------- 139
           L   +   +A  K PDA + +   +   A ++  +A++                      
Sbjct: 567 LPVYKYMLNAMHKHPDARILVNFASLRVAYDICMEAMEVDCILSSNYKENGILNEHSDTS 626

Query: 140 ----RNLNV--------MMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSM------IA 181
                 L V         + ++ +      +L  R+RE+ +L++GP     +      I 
Sbjct: 627 INHNDGLRVNEAQIKCIAIIAEGIPENMTRRLIQRSRERNILLIGPATVGGLKSGCFKIG 686

Query: 182 GTPLAFANV-----MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVG 236
            T     N+        G++  +  SG    EL + I++  +G+   + +GG        
Sbjct: 687 NTGGMTDNILASKLYRPGSVAYVSRSGGMSNELNNIISMNSDGVYEGVAIGGDRFP---- 742

Query: 237 GISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKA-TGKPTVALFLGY 289
           G + +  +     + +  ++  + +         I         KP VA  +G 
Sbjct: 743 GSTFIDHILRYENNPEIGMIVVLGEVGGVEEYAIIEAVKSGKIKKPIVAWCIGS 796


>UniRef50_B4D5E1 Succinate--CoA ligase (GDP-forming) n=1 Tax=Chthoniobacter flavus
           Ellin428 RepID=B4D5E1_9BACT
          Length = 168

 Score = 68.2 bits (165), Expect = 8e-10,   Method: Composition-based stats.
 Identities = 18/101 (17%), Positives = 44/101 (43%), Gaps = 3/101 (2%)

Query: 84  QLEEALKQLAQGSGSSQALTQVRRWDSA--CQKLPDANLALISVAGEYAAELANQALDRN 141
           QL   +     G        +V  +D+     K   A ++ I V   +AA+   + +D  
Sbjct: 34  QLVAGVTPGKGGQTFEHNGHKVPIFDTVGEAAKQTGATVSAIFVPPPFAADAILECVDAG 93

Query: 142 LNVMM-FSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           L++ +  ++ + + D +++K   + +   ++GP+C   +  
Sbjct: 94  LDLAVAITEGIPVSDMVKVKAAMQGRKTRLIGPNCPGLVTP 134


>UniRef50_A8PI61 ATP-citrate synthase, putative n=1 Tax=Brugia malayi
           RepID=A8PI61_BRUMA
          Length = 628

 Score = 67.8 bits (164), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 47/253 (18%), Positives = 89/253 (35%), Gaps = 35/253 (13%)

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLK--TRAREKGLLVMGP 173
           I V      +    A +++ +V +F       S  VT+ + +       A EKG+ ++GP
Sbjct: 154 ILVP---VYKSMKDAFNKHHDVSVFITFASLRSVYVTVREALDFAQIRLANEKGVTLIGP 210

Query: 174 DCGTSMIAG------TPLAFANV-----MPEGNIGVIGASGTGIQELCSQIALAGEGITH 222
                +  G      T     N+        G++  +  SG    EL + I+   +G+  
Sbjct: 211 ATVGGIKPGCFKIGNTGGMMDNILSLKLYRPGSVAYVSRSGGMSNELNNIISQNADGVYE 270

Query: 223 AIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAM-KATGKP 281
            I +GG     +  G + +  L     D++ +++  + +         +     K   KP
Sbjct: 271 GIAIGGD----KYPGSTFVDHLLRYEMDDRVKMMVMLGELGGVEEYKVVEALKEKRLTKP 326

Query: 282 TVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGT 341
            VA  +G        E  +  +     A+     ++  A + A A V + F         
Sbjct: 327 LVAWCIGTCADYVTFEIQFGHAGASANAKAETATAKNLALKEAGAHVPNSF-------DD 379

Query: 342 LAAEAAGLLAGHL 354
           L  E A +    L
Sbjct: 380 LGDEIAKIYKELL 392


>UniRef50_O28761 Putative uncharacterized protein n=1 Tax=Archaeoglobus fulgidus
           RepID=O28761_ARCFU
          Length = 881

 Score = 67.8 bits (164), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 40/226 (17%), Positives = 94/226 (41%), Gaps = 20/226 (8%)

Query: 96  SGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMM-----FSD- 149
           + +++A+  VR + +  +   +  LA++SV  +YA E+A +   + +  ++     F++ 
Sbjct: 233 NRAAKAIMGVRAYPTISEVPDEVELAVLSVPVKYALEVAEECGKKGVKALLVLTAGFAEV 292

Query: 150 -NVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPE-----GNIGVIGASG 203
               +E + +L    R+ G+ ++GP+C   +                   G+I     SG
Sbjct: 293 GGEGVERQKKLVEICRKYGMRLIGPNCMGIINTAPETRLLATFAPTPPNEGSIAFASQSG 352

Query: 204 TGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSK-P 262
                L  ++   G G+++ + LG          I++   +E    D +++++    +  
Sbjct: 353 AVGLALMDRVNNYGLGLSYFVSLG------NSADITSNDLIEFWEEDGRTKLIMLYQESI 406

Query: 263 PAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEA 308
           P      ++   +    KP +A+  G TPA A+       + +  +
Sbjct: 407 PNPRKFARLAKRISK-KKPILAIASGVTPAGAKAVASHTGAIVSSS 451


>UniRef50_C5A3W6 Acetyl-CoA synthetase (ADP forming), alpha chain (AcdA) n=4
           Tax=Thermococcus RepID=C5A3W6_THEGJ
          Length = 458

 Score = 67.4 bits (163), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 32/212 (15%), Positives = 75/212 (35%), Gaps = 15/212 (7%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDE 156
             + +  V+ + +      + +LA+I V   +  +      ++ +   ++ +       E
Sbjct: 46  KDEVVQGVKAYKNVKDIPDEVDLAIIVVPKRFVKQAIIDCGEKGVKGAVIITAGFGETGE 105

Query: 157 IQ------LKTRAREKGLLVMGPDCGTSMI--AGTPLAFANVMPEGNIGVIGASGTGIQE 208
                   L   A + G+ ++GP+C   M         F     +G+I  +  SG     
Sbjct: 106 EGKKEERELVEIAHKYGMRLIGPNCVGVMNTHNDMNATFIMDAKKGSIAFVSQSGALGAG 165

Query: 209 LCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVR 268
           +  +    G G +  + +G       +  +     +E L+   + + +A   +   +  +
Sbjct: 166 IVYKTVKEGIGFSKFVSVG------NMADLDFAELMEYLAETGEDKAIALYIEGLKDGRK 219

Query: 269 LKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
              V       KP +AL  G + + AR  +  
Sbjct: 220 FIEVAKKVTKKKPVIALKAGKSESGARAASSH 251


>UniRef50_Q05FP1 Succinyl-CoA synthetase alpha subunit n=1 Tax=Candidatus Carsonella
           ruddii PV RepID=Q05FP1_CARRP
          Length = 274

 Score = 67.0 bits (162), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 23/211 (10%), Positives = 84/211 (39%), Gaps = 15/211 (7%)

Query: 95  GSGSSQALTQVRRWDSACQKLPDAN--LALISVAGEYAAELANQALDRNLNVMM-FSDNV 151
            S +   +  +  + SA + +   N  ++++ +      +   + +   + +++  ++N+
Sbjct: 36  NSKNGGIVFHIPIYSSAIKAVKSNNCKISVLYIPYFVCKKTILENIYSGIKIIICITENI 95

Query: 152 TLEDEIQLKTRAREKGLLVMGPDCGTSMIA----GTPLAFANVMPEGNIGVIGASGTGIQ 207
           ++ D +++K    +  ++ +GP+    ++        +   +++ +G + +I  SGT   
Sbjct: 96  SVFDILKIKYYCEKYKIIFIGPNSPGLILPFLKIRLGIIPISIIKKGKLAIISKSGTLTY 155

Query: 208 ELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAV 267
           E   +I+    G +  IG+        + G +     +++  ++ ++ +  + +      
Sbjct: 156 E-AIKISSKIIGQSICIGI----GGDIISGCNIKNIFKLVFLNKFTKKILIIGEIGGN-- 208

Query: 268 RLKIVNAMKATGKPTVALFLGYTPAVARDEN 298
              ++   K   K      +G    + +   
Sbjct: 209 FENVITTCK-VNKKIFFYIVGIFSPLEKKMG 238


>UniRef50_A6C207 Acetyl-CoA synthetase / acetyltransferase (GNAT) family protein n=2
           Tax=Planctomycetaceae RepID=A6C207_9PLAN
          Length = 899

 Score = 66.6 bits (161), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 70/430 (16%), Positives = 140/430 (32%), Gaps = 66/430 (15%)

Query: 106 RRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQ 158
             + S        +LA+I    +   ++  Q     +  ++        +     E E+Q
Sbjct: 58  PCYQSVLDLPEPVDLAVICTPAQTIPDVIQQCGTAGIRGIVILSAGFRETGAAGKERELQ 117

Query: 159 LKTRARE-KGLLVMGPDCGTSMIAGTPL--AFANVMP-EGNIGVIGASGTGIQELCSQIA 214
           + + AR+  G+ ++GP+C   M     L  +FA  MP  GNI  I  SG     +     
Sbjct: 118 VLSIARQFSGMRIIGPNCLGIMAPYVNLNASFATDMPLTGNIAFISQSGALCTAVLDWAL 177

Query: 215 LAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNA 274
               G +H + +G       +  +     ++  + D +++ +    +   EA +      
Sbjct: 178 QEKVGFSHFVSVG------NMLDVGIADLIDYFALDPQTKSIILYVESITEARQFMSAAR 231

Query: 275 MKATGKPTVALFLGYTPAVARDENVW-----FASSLDEAARLACLLSRV---------TA 320
                KP +A   G     A+  +          ++ EAA     + RV           
Sbjct: 232 AFTKHKPIIAYKAGRFQESAKAASSHTGAMAGVDAVYEAAFARAGIVRVFELDDLFDCAE 291

Query: 321 RRNAIAPVSSGFICGLYTG---GTLAAEAAGLLAGHLGVEADDTHQHGMMLD----ADSH 373
                 P     +  L      G +  +A     G L   +++T +    +     +  +
Sbjct: 292 LLARHRPPRGERLAILTNAGGPGVMCTDALLERKGVLASLSEETIEQLNRVLPPAWSHGN 351

Query: 374 QIIDLGD---DFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAAS 430
            +  LGD   + +  G+   +I                QV  +L  VV+   A  DP  +
Sbjct: 352 PLDILGDALPERF--GKALEII------------LVDSQVDGVL--VVLSPQAMTDPTGA 395

Query: 431 LVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAA 490
             +  + A            + +  G  +  +  ++    L  AGI   ++  +A     
Sbjct: 396 ADAVIKAAKLTSK-----PILTSWMGGGKVLEGITR----LTAAGIPTYNTPEQAVRAFM 446

Query: 491 ALIHPLSPAA 500
            L+       
Sbjct: 447 YLVTYARNRE 456


>UniRef50_B8D575 AcdA-1 acetate--coA ligase (ADP-forming), alpha chain n=1
           Tax=Desulfurococcus kamchatkensis 1221n
           RepID=B8D575_DESK1
          Length = 481

 Score = 66.6 bits (161), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 47/248 (18%), Positives = 88/248 (35%), Gaps = 33/248 (13%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGSG----SSQALTQVRRWDSACQKLPDANLA 121
           VAI       G    I+  LE  +K+              +  ++ + S  +     +LA
Sbjct: 28  VAIVGATPKEGKVGRII--LENFIKKYKGRIYPVNPGYNEIMGLKCYRSVSELPETPDLA 85

Query: 122 LISVAGEYAAELANQALDRNLN-VMMFS---------DNVTLEDEIQLKTRAREKGLLVM 171
           +I V      E+  +  ++    V++ S         +   LE E  +K  A + G+ ++
Sbjct: 86  IIVVPAPSVPEVLRELGEKGCKAVIIISGGFKETGTPEGERLEHE--IKELAVKYGIRII 143

Query: 172 GPDCGTSMIAGTPL-------AFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           GP+C       + +             P+G +  I  SG     L   +A    G++ AI
Sbjct: 144 GPNCIGIFDNWSGVDTFFLPEEKMKRPPKGYVAFISQSGAFASALMDWMAYNNIGVSRAI 203

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATG--KPT 282
             G +    ++        LE L+ D+K+ V+    +    A     +   +     KP 
Sbjct: 204 SYGNKIDVDDI------DLLEYLAGDDKTRVILVYLEGLKNARGRIFIETARRVSRVKPV 257

Query: 283 VALFLGYT 290
           +    G T
Sbjct: 258 LVFKAGKT 265


>UniRef50_B8CEH1 Acetyl-coa synthetase n=1 Tax=Thalassiosira pseudonana
           RepID=B8CEH1_THAPS
          Length = 973

 Score = 66.6 bits (161), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 68/407 (16%), Positives = 137/407 (33%), Gaps = 57/407 (14%)

Query: 101 ALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMF-------SDNVTL 153
            +    R           ++A+I+V  ++  ++    ++  +   +        +     
Sbjct: 96  GIKSYTRVQDIPSSDGQIDMAVIAVNAKHVKQVMEDCVEVGIKAAVIISAGFKETGAEGA 155

Query: 154 EDEIQLKTRAREKGLLVMGPDCGTSMIAGTPL--AFAN-VMPEGNIGVIGASGTGIQELC 210
           + E ++   A +  + V+GP+C   M     L   FA  +   GN+  I  SG     + 
Sbjct: 156 QLEREVYEIACKGKIRVVGPNCLGVMNPIVGLNATFATQIAKPGNVAFISQSGAMCTSIL 215

Query: 211 SQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK 270
                A  G +  + +G       +  +S    +  L  D  ++ +A   +   +A    
Sbjct: 216 DWSLQANVGFSSFVSIG------SMLDVSWGDIIYYLGDDPNTKAIAIYMETIGDARSFM 269

Query: 271 IVNAMKATGKPTVALFLGYTPA-----VARDENVWFASSLDEAARLACLLSRVTARRNAI 325
              +  A  KP + +  G T        +   ++  +  + +AA   C + RV   R   
Sbjct: 270 SAASEVAMTKPIIVIKPGRTEQAAAAAASHTGSLAGSDDVLDAAFKRCGVLRVNKIREVF 329

Query: 326 APVS----SGFICGLY------TG--GTLAAEAAGLLAGHLGVEADDTHQHGMMLD---- 369
             V          G +       G  G ++ +A     G L   +DDT +    +     
Sbjct: 330 EIVELLGKQPRPKGKHLTIVTNAGGPGVISTDALIESGGQLSWISDDTMKSLNEILPPHW 389

Query: 370 ADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAA 429
           + S+ I  LGD             P    +++           +L  +V+   +  DP+A
Sbjct: 390 SHSNPIDILGDAT-----------PATYAKVVEIAAQDEYSDGIL--IVLTPQSMTDPSA 436

Query: 430 SLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGI 476
                  +   AR        +A+  G     +   +  A L++AGI
Sbjct: 437 -TARGIAE--IARKIGGRKPILASWMGG----KGVEEGRAILDEAGI 476


>UniRef50_A8ZSN5 CoA-binding domain protein n=3 Tax=Desulfobacteraceae
           RepID=A8ZSN5_DESOH
          Length = 492

 Score = 66.2 bits (160), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 42/198 (21%), Positives = 79/198 (39%), Gaps = 25/198 (12%)

Query: 110 SACQKLPDA-NLALISVAGEYAAELANQALDRNL-NVMMFSDNVT------LEDEIQLKT 161
            + + LP+A +LA+I +      E       + + N ++ S           E E +L  
Sbjct: 65  DSVESLPEAPDLAVIVLPTRIVCETMEACGKKGIRNAIVVSGGFKEVGPEGAEREKELAA 124

Query: 162 RAREKGLLVMGPDCGTSM-----IAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALA 216
            A + G+ ++GP+C         +  TP  +      G IG++  SG+ + ++ + +   
Sbjct: 125 IAGKYGISIIGPNCLGVTNAHARLNTTPHRYYG--KPGFIGLVSQSGSFVTQMFAYLDQL 182

Query: 217 GEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMK 276
             G + A  +G             +  LE L A   ++V+A   +  A     K V   +
Sbjct: 183 HLGFSTAFSIGNE------VNTDLVDCLEFLGACPDTKVIALYVE--AIRRGRKFVETAR 234

Query: 277 AT--GKPTVALFLGYTPA 292
                KP VAL++G +  
Sbjct: 235 KIVPHKPIVALYVGGSET 252


>UniRef50_C7DI26 CoA-binding domain protein n=1 Tax=Candidatus Micrarchaeum
           acidiphilum ARMAN-2 RepID=C7DI26_9EURY
          Length = 479

 Score = 66.2 bits (160), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 40/223 (17%), Positives = 82/223 (36%), Gaps = 18/223 (8%)

Query: 93  AQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN--VMMFSDN 150
              + +S  +  +  + +  +     +LA+I++  ++ +EL  +     +   V++ S  
Sbjct: 63  PVNANASGKILGLESYRNITEIKKPIDLAVIAIPAKFTSELITECHKAGVKSIVVVSSGY 122

Query: 151 VTLED---EIQLKTRAREKGLLVMGPDCGTSM-----IAGTPLAFANVMPE--GNIGVIG 200
             + +   E +L   A +  + ++GP+C   M     +    L    +     G +  + 
Sbjct: 123 AEIGEVKLEQELIDLANKYKIPLLGPNCLGVMDLKSRVDTLFLPTFKIDRPSIGGVSFVS 182

Query: 201 ASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVS 260
            SG         IA  G G++  I  G   +  E         L  L+ DE ++V+ +  
Sbjct: 183 QSGAVGSSTLDIIANEGFGLSKFISYGNASVIDE------TDILNYLAKDEDTKVILYYI 236

Query: 261 KPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFAS 303
           +                  KP V L  G T A ++  +   AS
Sbjct: 237 EGVKRGRAFIEAAKKATLKKPIVVLKGGRTEAGSKAAHSHTAS 279


>UniRef50_A1SKW5 CoA-binding domain protein n=3 Tax=Actinomycetales
           RepID=A1SKW5_NOCSJ
          Length = 899

 Score = 65.8 bits (159), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 43/259 (16%), Positives = 94/259 (36%), Gaps = 38/259 (14%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN--VMMFSDNVTLED 155
           +S A++ +  + +      D ++A+++V  E   ++      + ++  V++ S      +
Sbjct: 241 TSSAVSGLPTYKTVGDIPDDVDVAIVAVPAEAVQDVVLDCAAKGVHGLVVISSGFAETGE 300

Query: 156 EIQLKT-----RAREKGLLVMGPDCGTSMIAGTPLAFANVM-----PEGNIGVIGASGTG 205
           E +++       +R  GL ++GP+    +     ++    +     P G  G    SG  
Sbjct: 301 EGRVRQRKLVGLSRSYGLRLIGPNALGIINTAAEVSLNASLSPLMPPRGRAGFFCQSGAL 360

Query: 206 IQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAE 265
              +  ++   G G++  +  G R    +V G   L        D+ +EV+    +    
Sbjct: 361 GTAILEKVYNRGLGLSTFVSAGNR---ADVSGNDLLQ---YWEEDDSTEVVLLYLESIGN 414

Query: 266 AVRLKIVNAMKATGKPTVALFLGYTP--------------------AVARDENVWFASSL 305
             +   +    +  KP +A+  G T                     A+ R   V    +L
Sbjct: 415 PRKFSRIARRVSLRKPIIAVRSGRTTQGVPMGHAVRKIVAPPAAVDAMFRQAGVIQVDTL 474

Query: 306 DEAARLACLLSRVTARRNA 324
           +E   +A LL+     R  
Sbjct: 475 EEMFDVAQLLAHQPLPRGR 493


>UniRef50_Q0FX08 CoA-binding protein n=1 Tax=Roseovarius sp. HTCC2601
           RepID=Q0FX08_9RHOB
          Length = 701

 Score = 65.8 bits (159), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 44/199 (22%), Positives = 86/199 (43%), Gaps = 24/199 (12%)

Query: 112 CQKLPDANLAL-ISVAGEYAAELANQALDRNL-NVMMFSDNVT-------LEDEIQLKTR 162
              LP+A   + I V G+    +  Q  DR + +V +FS   +          + ++   
Sbjct: 65  IASLPEAPDHVGIVVPGKAIPGVLKQCGDRGVRHVTIFSSGFSEGGSADGAAFQAEIVAL 124

Query: 163 AREKGLLVMGPDCGTSM--IAGTPLAFANVM-----PEGNIGVIGASGTGIQ-ELCSQIA 214
           ARE G+ +MGP+C   +  + G  L     +     P+G++ V+G SG   Q  +  +  
Sbjct: 125 AREHGIRLMGPNCNGLINYVDGFALTSTATINGPRAPKGDVAVLGHSGGLAQVNVMYRAQ 184

Query: 215 LAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIV-N 273
            AG GI++ +  G          +  L     +  D ++ V+  +++   +  +L+ + +
Sbjct: 185 QAGLGISYQVSCGND------ADLDILDYAAFMVDDPETRVILMLAETIRDGGKLRALSD 238

Query: 274 AMKATGKPTVALFLGYTPA 292
             +A  KP V + LG +  
Sbjct: 239 RARAADKPIVMMKLGRSEE 257


>UniRef50_B6YUH0 Archaeal succinyl-CoA synthetase (NDP forming), large subunit n=9
           Tax=Thermococcaceae RepID=B6YUH0_THEON
          Length = 469

 Score = 65.8 bits (159), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 72/399 (18%), Positives = 136/399 (34%), Gaps = 65/399 (16%)

Query: 94  QGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN--VMM---FS 148
           +G        +   + S  +   + ++A+I+V  ++  ++ ++  ++ +   V++   F 
Sbjct: 49  KGGEVEVNGKKFPVYRSIKEISDEIDVAVIAVPAKFVPDVIDECGEKGVKGAVVISAGFK 108

Query: 149 DNVTLEDEIQLKTRAREKGLLVMGPDC--GTSMIAGTPLAF-----ANVMPEGNIGVIGA 201
           +    + E ++  RAR+ G+ ++GP+C   T++  G    F         P G I  +  
Sbjct: 109 EAGRADLEEEIVKRARKWGIRLVGPNCLGVTNLENGFDCNFNPPERQARPPAGKIAFMSQ 168

Query: 202 SGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSK 261
           SG       + +  A    +H IG+        +  +     +  L  D K+ V+     
Sbjct: 169 SGAFG---AAILDWAA---SHKIGMSKFISLGNMADLDESDFMAYLGEDPKTGVIT--GY 220

Query: 262 PPAEAVRLKIVNAMKA--TGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVT 319
                   K  N  K     KP + L  G T A A+               LA   +   
Sbjct: 221 IEGVKDGRKFFNTAKEVTLKKPVIILKSGRTEAGAKAAASH-------TGSLAGSYAIYQ 273

Query: 320 ARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLG 379
           A       + +  +  L+      A+A  +    +G         G      S  +++ G
Sbjct: 274 AAFKQAGVLEAKSMRQLFN----YAKALAMQKPAMGNRVAIVTNGGGAGVMMSDGLLERG 329

Query: 380 DD--FYT------------VGR-PHPM-----ID-----PTLRNQLIADLG-AKPQVRVL 413
            +   +T             G+ PH M     ID     P+ R +         P V VL
Sbjct: 330 MELAEFTEQTNERFRKDIEEGKLPHHMSYKNPIDVIGDAPSNRYERAMRYALEDPNVDVL 389

Query: 414 LLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIA 452
              VVI    +      +V A  K        +P+  +A
Sbjct: 390 ---VVIALFQSPALDEGIVDAVAKMQEY---GKPIVFVA 422


>UniRef50_Q2LVD4 Acetyl-CoA synthetase beta subunit n=1 Tax=Syntrophus
           aciditrophicus SB RepID=Q2LVD4_SYNAS
          Length = 773

 Score = 65.5 bits (158), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 43/220 (19%), Positives = 81/220 (36%), Gaps = 18/220 (8%)

Query: 111 ACQKLPDA-NLALISVAGEYAAELANQALDRNLNVMM-----FSDN--VTLEDEIQLKTR 162
           + + LP+A +LAL++V G   A +  +   + +   +     FS+      E E  +   
Sbjct: 344 SIEALPEAPDLALLTVGGRQVASMLKECGRKQIPAAIAIAAGFSETGAAGAEAEQDIARI 403

Query: 163 AREKGLLVMGPDCGTSMIAGT---PLAFANVMP-EGNIGVIGASGTGIQELCSQIALAGE 218
           A E G+ VMGP+C   +        + F  + P  G +  +  SG    ++ +     G 
Sbjct: 404 ATEGGVTVMGPNCMGMISNEVQLHAVGFVALHPARGTLSFVSQSGNLGSQVVNGCRRRGI 463

Query: 219 GITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKAT 278
           GI     +G      ++G ++    L+ L  D  +  +    +   +           A 
Sbjct: 464 GIDKFASVGNE---AQIGAVN---VLDYLRDDPNTSCVLMYIEGIDDGRLFLDAARRTAA 517

Query: 279 GKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRV 318
            KP V L  G T + ++       +    AA       + 
Sbjct: 518 VKPVVVLRAGLTESGSKAAASHTGAMAGSAAVWEAAARQA 557


>UniRef50_C5A3H6 Acetyl-CoA synthetase (ADP forming), alpha chain (AcdA) n=4
           Tax=Thermococcus RepID=C5A3H6_THEGJ
          Length = 537

 Score = 65.5 bits (158), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 38/229 (16%), Positives = 82/229 (35%), Gaps = 17/229 (7%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQL---AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+        IA  I++ + E   +                 R ++   +     + A+
Sbjct: 12  VAVFGSFRKGAIAYEILRNIVEGGFEGKIIPVNPKGGSVEVAGRVFEIRERLDEPVDTAI 71

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVT----LEDEIQLKTRAREKGLLVMGPDCGTS 178
           I++  ++   L ++   R    ++ S   +     + E +L  +AR+ G+ ++GP+C   
Sbjct: 72  IAIPAKFVPGLIDEIGPRIKGAVVISAGFSEVGNADLERELVEKARKHGVRLIGPNCAGI 131

Query: 179 -MIAGTPLA-FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLG-GRDLSREV 235
             + G     F   +  G + +I  SG       +     G G +  +  G   DL+   
Sbjct: 132 FGVHGKFFGSFEVRVKPGGLALISQSGAFGGAALAMGNEEGIGFSAFVSYGNAADLNES- 190

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
                   LE  + DE ++ +A   +   +        +  +  KP + 
Sbjct: 191 ------DFLEYFADDENTKAIALYIEGVKDGRHFLKALSYASKRKPVIV 233


>UniRef50_C5A4T1 Acetyl-CoA synthetase (ADP forming), alpha chain (AcdA) n=9
           Tax=Thermococcaceae RepID=C5A4T1_THEGJ
          Length = 474

 Score = 65.1 bits (157), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 41/232 (17%), Positives = 86/232 (37%), Gaps = 31/232 (13%)

Query: 102 LTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLED----- 155
           +   + + S  +   D +LA+IS+   +  +   Q  ++ +  V++ +            
Sbjct: 61  IEGYKVYHSVEELPDDTDLAVISIPAPFVPDTMRQIAEKGIKAVIIITGGFGELGEEGKK 120

Query: 156 -EIQLKTRAREKGLLVMGPDCGTSMIAGTPL-------AFANVMPEGNIGVIGASGTGIQ 207
            E ++   A+  G+ V+GP+C    +  T +       +  +    G I  +  SG    
Sbjct: 121 LEREIYEIAKANGIRVIGPNCVGVYVPDTGVDTVFLPESKMDRPQSGPIAFVSQSGAFAA 180

Query: 208 ELCSQIALAGEGITHAIGLGGR-DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEA 266
            +    A+AG GI   +  G + D+            ++    D+   V+ F  +     
Sbjct: 181 AMLDWAAMAGIGIGKMVSYGNKIDVDDA-------DLMDYFIHDDGINVVTFYIE--GVK 231

Query: 267 VRLKIVNAMKATG--KPTVALFLGYT-----PAVARDENVWFASSLDEAARL 311
              K + + K     KP +AL  G T      A +   ++  A ++ +A   
Sbjct: 232 DGRKFMESAKRITRVKPVIALKSGRTEYGAKAASSHTGSLAGADTIYDAVFK 283


>UniRef50_A3TZP5 Acetyl-CoA synthetase n=1 Tax=Oceanicola batsensis HTCC2597
           RepID=A3TZP5_9RHOB
          Length = 699

 Score = 65.1 bits (157), Expect = 7e-09,   Method: Composition-based stats.
 Identities = 47/280 (16%), Positives = 93/280 (33%), Gaps = 30/280 (10%)

Query: 66  VAIRSEAADAGIAQA------IMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDAN 119
           VA+   + D            I    +  +  +   S   Q L        A    PD  
Sbjct: 10  VAVIGASGDPKRIGGRPVDFLIRHGFDGPILPINPKSPQVQGLAAYPSISEA-PTTPD-- 66

Query: 120 LALISVAGEYAAELANQALDRNLN-VMMFSDNVTLED------EIQLKTRAREKGLLVMG 172
           +A+I++    A +   Q   R +   ++FS   +  D      + ++   ARE G+ ++G
Sbjct: 67  MAVIALPAPLAVQAVEQCAARGVRGAVIFSSGFSEVDADGAALQARMVDIAREGGMRLVG 126

Query: 173 PDCGTSM-------IAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIG 225
           P+C              TP    ++   G + ++  SG       + + + G G+     
Sbjct: 127 PNCLGIANVRHNLYATFTPGVEKHLPKPGGVSIVSQSGAFGSYCMTLVRMRGLGVNIWAT 186

Query: 226 LGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVR-LKIVNAMKATGKPTVA 284
            G          +    A+   + D+ + V+    +   +  R ++ +   +A  KP V 
Sbjct: 187 TG------NSCDVDFADAVAYCAQDDDTRVIMGYLEGATDRDRLVEALEMARAREKPVVM 240

Query: 285 LFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNA 324
           + +G +   A       AS     A       +    R  
Sbjct: 241 MKVGRSAVGAEAAQSHTASLAGADAVYDAAFRQYGVYRAQ 280


>UniRef50_A0LL44 CoA-binding domain protein n=2 Tax=cellular organisms
           RepID=A0LL44_SYNFM
          Length = 669

 Score = 64.7 bits (156), Expect = 9e-09,   Method: Composition-based stats.
 Identities = 42/241 (17%), Positives = 89/241 (36%), Gaps = 26/241 (10%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQLAQGSGSSQALTQVR-RWDSACQKLPD-ANLAL 122
           VA+   +  AG     I++ L E     A    + +A   +        + +PD  ++A+
Sbjct: 15  VAVIGASDSAGKLGHEILKNLIEGGFPGALYPINPKAEKILGLTCFKNVKDIPDQVDMAV 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMF---------SDNVTLEDEIQLKTRAREKGLLVMGP 173
           + +      +      ++ +   +          ++   L++E  L   A    + ++GP
Sbjct: 75  VIIPARMVPQAVRDCGEKGVKGAVIVTGGFSEAGAEGAKLQEE--LVRVASNYDIRLVGP 132

Query: 174 DCGTSMIAGTPLAFAN--VMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
           +C        P+  +   +  +G + VI  SGT    +    ++   G++  + LG R  
Sbjct: 133 NCQGVNNPHHPMCASWPLLTHKGRVAVISQSGTVGAAMMDWFSVEELGVSSFVSLGNRAD 192

Query: 232 SREVGGISALTALEMLSADEKSEVL-AFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
             EV        +E    D  ++V+  ++          +  + +    KP V L  G T
Sbjct: 193 IDEV------DLIEYFEGDPNTKVIAVYIEGIKDP---QRFRDVLSTLSKPLVVLKSGRT 243

Query: 291 P 291
           P
Sbjct: 244 P 244


>UniRef50_B8D4Z1 Acetyl-CoA synthetase n=1 Tax=Desulfurococcus kamchatkensis 1221n
           RepID=B8D4Z1_DESK1
          Length = 471

 Score = 64.7 bits (156), Expect = 9e-09,   Method: Composition-based stats.
 Identities = 38/196 (19%), Positives = 77/196 (39%), Gaps = 26/196 (13%)

Query: 104 QVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQ 158
             + + S      + ++A+++V  +   E+  ++  + + V +     FS+   +E E +
Sbjct: 62  GYKAYPSILDVPDEVDVAIVTVPADNVPEVIEESGRKGVKVAVVITSGFSEVGNVELENK 121

Query: 159 LKTRAREKGLLVMGPDCGTSMIAGTPLAFANV--------MPEGNIGVIGASGTGIQELC 210
           +   AR+ G+ ++GP+     I G     +N+        +  G+I +I  SG       
Sbjct: 122 IVETARKYGMRILGPN-----IFGYVYTPSNINATFGPLEVARGSIALISQSGALG---- 172

Query: 211 SQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK 270
             IAL G  I + IGL        +  +      E L+ D  + V+    +        +
Sbjct: 173 --IALMGWTIMNEIGLSALLSVGNMADLDVAELSEYLADDPNTRVITIYLEGIKPGRGGE 230

Query: 271 IVNAMKA--TGKPTVA 284
            +  M+     KP V 
Sbjct: 231 FIKKMREVTLKKPVVV 246


>UniRef50_B8FE80 CoA-binding domain protein n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FE80_DESAA
          Length = 725

 Score = 64.3 bits (155), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 38/204 (18%), Positives = 73/204 (35%), Gaps = 24/204 (11%)

Query: 112 CQKLPD-ANLALISVAGEYAAELANQALDRNLN-VMMFS---------DNVTLEDEIQLK 160
              LP+  +L ++SV  +    +  + +      + +F+         + V L+ E+  K
Sbjct: 311 LTALPEKVDLVIVSVPAQVVPGVLRECVATGNKTIHIFTAGFKESGEEEGVRLQKEM--K 368

Query: 161 TRAREKGLLVMGPDCGTSMIAGTPL---AFANVMPEGNIGVIGASGTGIQELCSQIA-LA 216
             A E GL V+GP+C    +    +     A+    G I +I  SG   QE+        
Sbjct: 369 QIAVEGGLRVIGPNCMGFYVPNRRMLTWQKASK-KSGPIALISQSGGNAQEITHYATGRY 427

Query: 217 GEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMK 276
           G G    +  G                L+ L+ D+++E++    +      R   +    
Sbjct: 428 GIGFNKVVSYGNALTVES------ADFLDYLAGDDETEIITMYLEGLKNGRRFLKLAEET 481

Query: 277 ATGKPTVALFLGYTPAVARDENVW 300
              KP +    G +   A+  +  
Sbjct: 482 NKKKPILIYKGGLSETGAQAVSSH 505


>UniRef50_Q979A5 Succinyl CoA synthetase alpha subunit n=2 Tax=Thermoplasma
           RepID=Q979A5_THEVO
          Length = 693

 Score = 64.3 bits (155), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 47/250 (18%), Positives = 98/250 (39%), Gaps = 22/250 (8%)

Query: 63  DICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQ--ALTQVRRWDSACQKLPDANL 120
           D    I +   +  I   I++ L+E   +      +++   +   + + S      + +L
Sbjct: 10  DSVAVIGASNDNTKIGYQIIRNLKEGGYKGKIYPINTKDGTILGYKAYPSILDVPDEVDL 69

Query: 121 ALISVAGEYAAELANQALDRNLNVMM-----FSD--NVTLEDEIQLKTRAREKGLLVMGP 173
           A++S+  +Y  + A +   + +  ++     FS+  N  LED++      ++ G+ ++GP
Sbjct: 70  AILSIPAKYTPQAAEECGRKGVFGIIVVASGFSEVGNKDLEDQLA--NTCKKYGVRLLGP 127

Query: 174 DCGTSMIAGTPL--AFANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
           +    M     L  +FA  +P  G IG+I  SG  I  L +       G +  I +G   
Sbjct: 128 NVVGLMNNVIKLNASFAPYLPYPGTIGMISQSGALIVGLDAMTWANKTGTSFLISIG--- 184

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
               +  +     +  L+ DE    ++  ++        K V+  +   KP V L  G +
Sbjct: 185 ---NMADLDFSDLVTFLADDENVSCISLYAE--GLKAGRKFVDTARLINKPIVMLKSGVS 239

Query: 291 PAVARDENVW 300
              +      
Sbjct: 240 KHGSVAAASH 249


>UniRef50_Q0S4P1 Probable acid--CoA ligase n=2 Tax=Rhodococcus RepID=Q0S4P1_RHOSR
          Length = 687

 Score = 64.3 bits (155), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 82/423 (19%), Positives = 149/423 (35%), Gaps = 50/423 (11%)

Query: 110 SACQKLPDANLALISVAGEYAAELANQALDRNLNVMM-FSDNVTLEDEIQLKTRAREKGL 168
           SA  ++PD  L  + V   + +++ ++AL   +   +  +  V  E E+  +   R  G 
Sbjct: 70  SALPEVPD--LVALCVPAPFVSDVVDEALTLGVRGFLGVTAGVPGEAELAAR--IRSAGA 125

Query: 169 LVMGPDCGTSMIAGTPLAFA-NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLG 227
            ++G +      + T L+ A      G + +I  SG    EL +  A  G G++  + +G
Sbjct: 126 RLVGTNSLGIYDSATDLSLAWGRFTPGPLAIISQSGQLGSELAALGARHGVGVSRFVSIG 185

Query: 228 GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAE-AVRLKIVNAMKATGKPTVALF 286
            +        ++A   L  L   + + V+A   +  ++     + + A++ TG+PT+ L 
Sbjct: 186 NQ------SDVTAAELLAELGGHDPTRVIALYLESFSDGESLFRTLRALRDTGRPTLLLT 239

Query: 287 LGYTPAVAR-----DENVWFASSLDEAARLACLLSRVTARRNAIA-----------PVSS 330
           +G + A  R       ++  A  + +AA  A  + RV++    I              + 
Sbjct: 240 VGASAASTRLARSHTGSLTSALDVVDAACRAAGVLRVSSPDELITVARAFLSTTVPAGNR 299

Query: 331 GFICGLYTGGTLAAEAAGLLAGHLGVEA-DDTHQHGMMLD----ADSHQIIDL-GDDFYT 384
             I G  +GG  A  A    A  L V          + L     A S+  +DL G     
Sbjct: 300 VAIVG-DSGGQCAIAADVTSASALTVPDFSPALAESVALQLPAGAASNNPVDLAGAGEQD 358

Query: 385 VGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLD 444
           +G    ++   LR        A     V+L      +   A   A   +A  +       
Sbjct: 359 LGSYASVVGRLLR--------ADESDAVVLTGYFGCYARDAPTLAEHEAAVAERIGRASA 410

Query: 445 NQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHT 504
                 +      E      S     L   G+ V  ++  A    + L     P    H 
Sbjct: 411 ETGKPVVVHTMAPE------SSTAQALWRHGVPVFDTVDSAVRALSGLSRLRPPQPSNHA 464

Query: 505 PSL 507
            S 
Sbjct: 465 LSE 467


>UniRef50_B5YGJ9 Acetyl-CoA synthetase n=1 Tax=Thermodesulfovibrio yellowstonii DSM
           11347 RepID=B5YGJ9_THEYD
          Length = 695

 Score = 64.3 bits (155), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 38/205 (18%), Positives = 74/205 (36%), Gaps = 25/205 (12%)

Query: 111 ACQKLPD-ANLALISVAGEYAAELANQALDRNLN-VMMFSDNVT------LEDEIQLKTR 162
           +   +PD  +LA+I +  +  A+         +  V++ +          +  E ++   
Sbjct: 57  SVSAIPDRVDLAIIVIPAKAVADSLKDCAKAGVKGVVVITAGFKEVGGDGVAREKEIVEI 116

Query: 163 AREKGLLVMGPDCGTSM--IAGTPLAFANVMPE-GNIGVIGASGTGIQELCSQIALA--- 216
            R  G+ ++GP+C   M        +FA  +P  G +     SG       + I  A   
Sbjct: 117 VRSAGIKMVGPNCLGVMNTKNKMNASFAAELPPEGRVAFFSQSGALG---VAIIDWAIEN 173

Query: 217 GEGITHAIGLGGR-DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAM 275
             G +  +  G + DL+           LE  + D  ++V+    +   +  R   +   
Sbjct: 174 NFGFSKFVSFGNKADLNE-------TDFLEYFAKDPDTDVILGYIEDVIDGKRFIEIAKE 226

Query: 276 KATGKPTVALFLGYTPAVARDENVW 300
               KP + +  G T A AR  +  
Sbjct: 227 VTKIKPVILIKSGATEAGARAASSH 251


>UniRef50_C5D0J6 CoA-binding domain protein n=1 Tax=Variovorax paradoxus S110
           RepID=C5D0J6_VARPS
          Length = 710

 Score = 64.3 bits (155), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 43/229 (18%), Positives = 87/229 (37%), Gaps = 22/229 (9%)

Query: 110 SACQKLPDAN-LALISVAGEYAAELANQALDRNLNVMMF-SDNVTLEDE------IQLKT 161
           ++  +LP+   LA+I+V      +       R +   +  S   +   E       ++  
Sbjct: 65  ASVAELPEVPELAVIAVPPAGVLDAVQDCAQRGVKAAVILSAGFSEMGEEGSRLQARIGE 124

Query: 162 RAREKGLLVMGPDCGTSM------IAGTPLAFANVMPE-GNIGVIGASGTGIQELCSQIA 214
            AR  G+ ++GP+C  ++      IA   +A  +  P  G++G++  SG           
Sbjct: 125 VARASGMRIVGPNCLGAIGVPDKSIATFSVALESSFPAAGSVGIVSQSGNLGSFTLRMAG 184

Query: 215 LAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRL-KIVN 273
             G G++  +  G          +    A+  L+AD  + V+    +   +  +L + + 
Sbjct: 185 ERGLGVSRMLTTGNE------CDVDIADAIASLAADPGTSVILCCMETCRDGAKLMQAMA 238

Query: 274 AMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARR 322
             +  GKP V L +G + A +        +     A    +L +  A R
Sbjct: 239 MAREAGKPLVVLKVGVSEAGSAAAASHTGALAGSDAVFDAVLRQGGALR 287


>UniRef50_C0QHB0 SucD4 n=1 Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QHB0_DESAH
          Length = 897

 Score = 63.9 bits (154), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 40/238 (16%), Positives = 76/238 (31%), Gaps = 17/238 (7%)

Query: 96  SGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNV-MMFSDNV--- 151
           S   + +  V+ +          +LA+I    +   E+  Q   R     ++ +D     
Sbjct: 48  STEFKTIEGVKTYPDVASLPRAPDLAVIVTPPDTIPEMIAQLGKRGTRAAVVLTDGFTND 107

Query: 152 --TLEDEIQLKTRAREKGLL--VMGPDCGTSMIAGTPL--AFANVMP-EGNIGVIGASGT 204
                 E+ +   A  +  L  ++GP     M+ G  L  +F +  P  GN+ ++  SGT
Sbjct: 108 TDPHHQELNMAMLAAARPHLFRIVGPSSLGVMVPGIGLNASFGHAPPLSGNLALVAQSGT 167

Query: 205 GIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPA 264
            +  +       G G +  + LG      E+        L+ L+ D  ++ +    +   
Sbjct: 168 VLTAVLDWGTSQGIGFSKCVALG------EMADGDFGDMLDYLAYDYSTQAILLYIEEIT 221

Query: 265 EAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARR 322
            A +        A  KP + +  G                    A       R    R
Sbjct: 222 GARKFISAARAVARIKPVIVVKAGRHGENVLAPASHTGFPTGSDAFYDAAFRRTGMLR 279


>UniRef50_Q3SEU0 Long-chain fatty-acid-CoA ligase n=4 Tax=Proteobacteria
           RepID=Q3SEU0_THIDA
          Length = 892

 Score = 63.9 bits (154), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 39/235 (16%), Positives = 79/235 (33%), Gaps = 16/235 (6%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNL-NVMMFSDNVT---- 152
               +   R +  A +      LALI+      A +  +   R + + ++ S        
Sbjct: 50  KHAEIFGERCYARASELPATPELALIATPATTVAAILEECGQRGIRHAIVLSAGFAETGT 109

Query: 153 --LEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQ 207
             +E E  L+  A++ G+  +GP+C         L           G++ ++  SG    
Sbjct: 110 QGIELEAGLQRVAKQHGIRFIGPNCLGIQRPAIGLNATFSQGATQAGDLALVSQSGALCT 169

Query: 208 ELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAV 267
            +       G G +  +  G          +     L+ L+ D +++ +    +   +A 
Sbjct: 170 AMLDWAEANGIGFSSVVSTG------ASADLDFGEILDYLAYDRQTKGILLYIEGIRDAR 223

Query: 268 RLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARR 322
           R        +  KP V + +G   A +R       + +   A    L+ R    R
Sbjct: 224 RFMSALRATSRFKPIVMVKVGRHEAGSRAVQSHTGALVGSDAVFDALVRRAGVVR 278


>UniRef50_O28341 Putative uncharacterized protein n=3 Tax=Archaeoglobus fulgidus
           RepID=O28341_ARCFU
          Length = 673

 Score = 63.9 bits (154), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 37/189 (19%), Positives = 76/189 (40%), Gaps = 25/189 (13%)

Query: 117 DANLALISVAGEYAAELANQALDRNLN-VMMFSDNVT------LEDEIQLKTRAREKGLL 169
           + ++A+I+V  +   E+  +   + +   ++ S   +       E E ++   A++ G+ 
Sbjct: 281 EVDMAIIAVPAKIVPEVMAECAQKGIKGAVIVSSGFSEEGEKGAEYERRVLEIAKKHGIR 340

Query: 170 VMGPDCGTSMIA-----GTPLAFANVMPEGNIGVIGASG--TGIQELCSQIALAGEGITH 222
           + GP+  T ++       T  A   V+ +GNIG+I  +G   GI            G + 
Sbjct: 341 IFGPNT-TGVLNTENGFITSFAIQPVIKKGNIGIIAQTGLFLGIMMDIVTSNHPSIGFSK 399

Query: 223 AIGLGGR-DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKP 281
            +G+G + D+            L+ L  DE+++V+    +           +   +  KP
Sbjct: 400 IVGMGNKIDVEDY-------EVLDFLLKDEQTKVIGIYME--GIKNGRAFYDVASSAEKP 450

Query: 282 TVALFLGYT 290
            V    G T
Sbjct: 451 IVVFKSGRT 459


>UniRef50_D1ZXC1 Whole genome shotgun sequence assembly, contig_2650 (Fragment) n=1
           Tax=Sordaria macrospora RepID=D1ZXC1_SORMA
          Length = 252

 Score = 63.5 bits (153), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 16/88 (18%), Positives = 38/88 (43%), Gaps = 2/88 (2%)

Query: 91  QLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMM-FSD 149
              +G      L        A  K   A+ ++I V   +AA+   +A+D  + +++  ++
Sbjct: 166 TPGKGGTEHLGLPVYNTVAEAKSK-TGADASVIYVPPPFAADSILEAIDAEIPLIVAITE 224

Query: 150 NVTLEDEIQLKTRAREKGLLVMGPDCGT 177
            + + D +++K         ++GP+C  
Sbjct: 225 GIPVLDMVKVKRALSGSKSRLIGPNCPG 252


>UniRef50_Q2Y4P6 Probable acetyl-CoA synthetase n=1 Tax=uncultured archaeon
           RepID=Q2Y4P6_9ARCH
          Length = 895

 Score = 63.5 bits (153), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 56/331 (16%), Positives = 108/331 (32%), Gaps = 56/331 (16%)

Query: 118 ANLALISVAGEYAAELANQALDRNLN-VMMFS--------DNVTLEDEIQLKTRAREKGL 168
            +LA+I+V   +  ++  +     +  V++ S        +   LE+  ++   AR  G+
Sbjct: 70  IDLAIIAVPATHVPDILEECGVAGVGGVIIISAGFKEIGKEGRKLEE--RIGKIARRYGI 127

Query: 169 LVMGPDCGTSMIAGTPL--AFANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIG 225
            ++GP+C   ++    L  +FA++MPE G++  I  SG     +    A    G +  + 
Sbjct: 128 RIIGPNCLGIIMPRFSLNASFAHLMPEHGSVAFISQSGALCTAVLDMCAHRHIGFSAFVS 187

Query: 226 LGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVAL 285
           +G       +  +     ++    D  +  +    +   +           A  KP + +
Sbjct: 188 IG------SMLDVDFGDLIDYFGMDPATGSIMLYIESLKDVREFMSAARHFAKNKPIIVV 241

Query: 286 FLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTL-AA 344
             G            FA S   AA     L+      +A     +G I  L        +
Sbjct: 242 KSGR-----------FARSAKAAASHTGALAGDDNFYDAAF-KRAGAIRVLEIEDLFDCS 289

Query: 345 EAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADL 404
            A  +     G         G      + ++ID G                     +   
Sbjct: 290 AALAVQTRPHGPRLAIITNAGGPGVLAADRLIDKG--------------------GVIAE 329

Query: 405 GAKPQVRVLLLDVVI-GFGATADPAASLVSA 434
            +   V    LD V+  F +  +P   L  A
Sbjct: 330 LSDETVEA--LDKVLPPFWSRENPVDVLGDA 358


>UniRef50_B2T9W3 GCN5-related N-acetyltransferase n=1 Tax=Burkholderia phytofirmans
           PsJN RepID=B2T9W3_BURPP
          Length = 834

 Score = 63.1 bits (152), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 70/390 (17%), Positives = 113/390 (28%), Gaps = 56/390 (14%)

Query: 115 LPDAN-LALISVAGEYAAELANQALDRNLNVMMFSDNVTL-EDEIQLKTR---AREKGLL 169
           LP+A  +ALI         + ++         +    V   ED + L+     AR   L 
Sbjct: 66  LPEAPTVALICTPPATWPGIIHKLGGLGTRAAIIVGEVRCDEDRLALRHALSAARPNLLR 125

Query: 170 VMGPDCGTSMIAGTPL-----AFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           ++GP  G+  +    L     A +  +  G +  +  S      +       G G +HA+
Sbjct: 126 IVGP--GSLGVVSPALRAHLGAPSCTVKAGGVAWVSQSNALTNAVLGWAHARGLGFSHAV 183

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
            LGG         + A   L+ L++D  +  +         A +        A  KP +A
Sbjct: 184 ALGGE------ADVDAGDVLDYLASDPGTRAILLELDSVRAARKFMSAARAAARNKPVLA 237

Query: 285 LFLGYTPAVA-------RDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLY 337
           L  G             R   +    +LD+       L        A A + +    GL 
Sbjct: 238 LRSGRADPADALYTAAFRRAGMVRVDALDDLLDEIETLGVGRVAAGATATLITSD-RGL- 295

Query: 338 TGGTLAAEAAGLLAGHLGVEADDTHQ--HGMMLDADSHQIIDLGDDFYTVGRPHPMIDPT 395
              TLA +A       L    D+        +  A     ++LGDD     RP    +  
Sbjct: 296 --ATLACDAFAAAGDTLAPWPDEASDALKQSLPYAVGGNPLELGDDA----RP----EHF 345

Query: 396 LRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVT 455
                +                V+       P   +  A                   V 
Sbjct: 346 GTALKLLAEHRSTGTA-----FVVHASTHGAPVGEVAQALIANQRYAYRGLLACFFGGVD 400

Query: 456 GTERD------------PQCRSQQIATLED 473
              RD            PQ  ++  A L D
Sbjct: 401 AATRDALHAQGIPVHTTPQRLARAFARLVD 430


>UniRef50_Q0S1K2 Possible acetyl-CoA synthetase n=10 Tax=Actinomycetales
           RepID=Q0S1K2_RHOSR
          Length = 920

 Score = 62.8 bits (151), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 46/247 (18%), Positives = 92/247 (37%), Gaps = 25/247 (10%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGS-----GSSQALTQVRRWDSACQKLPDANL 120
           VA+   + D       +  L   L+    G         +++  VR + S      + +L
Sbjct: 244 VAVIGASTDRAKVGNAV--LTNLLRAGFTGPVYPVNAEHRSVHGVRAYPSVRDIPDEVDL 301

Query: 121 ALISVAGEYAAELANQALDRNLN-VMMFSDNVT------LEDEIQLKTRAREKGLLVMGP 173
           A+++V  E    + +  L + +  +++ S   +       + E +L   AR  G+ ++GP
Sbjct: 302 AVVAVPAESINAVLDDCLVKGVKALVVVSSGFSETGMDGRQSERRLVHAARAHGMRLIGP 361

Query: 174 DCGTSMIAGTPLAF----ANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
           +        + ++     A V+P  GN+G    SG     +  + A +  G++  +  G 
Sbjct: 362 NALGVANNDSEVSLNATLAPVLPSPGNVGFFCQSGALGIAILDEAARSRIGLSAFVSAGN 421

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG 288
           R    +V G   L       +D  +EV+    +      +   +    A  KP VA+  G
Sbjct: 422 R---ADVSGNDLLQ---YWDSDPATEVVLLYLESFGNPRKFSRIARRVARNKPIVAVKSG 475

Query: 289 YTPAVAR 295
                  
Sbjct: 476 RHAVPPA 482


>UniRef50_Q89VS0 Bll0975 protein n=1 Tax=Bradyrhizobium japonicum RepID=Q89VS0_BRAJA
          Length = 739

 Score = 62.8 bits (151), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 43/196 (21%), Positives = 77/196 (39%), Gaps = 24/196 (12%)

Query: 110 SACQKLPDANLALISVAGEYAAELANQALDRNLNV--MMFSDNVTLED------EIQLKT 161
           +A  + PD    L+ V   +A ++   A         ++ S    L+D        +L+ 
Sbjct: 86  AALPEKPDH--VLVLVPARFAVQVIRDAAAAGARSATIVTSGFSELQDDESQQLAAELQA 143

Query: 162 RAREKGLLVMGPDCGTSMIAGTPLAFANV------MPEGNIGVIGASGTGIQELCSQIAL 215
             RE GL V GP+C  ++ AG  L F N+      M +G + + G SG  +  +   +  
Sbjct: 144 AIRETGLAVTGPNCLGNLSAGEKL-FTNIDDRIVTMEQGAVAIAGQSGAIVMAIRQALED 202

Query: 216 AGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK-IVNA 274
            G G+ + +  G         G+     +   + D   +V+    +        +    A
Sbjct: 203 RGVGVGYMVTTGNE------AGLETPDLMRYFAEDPSVKVIVVYLEGVRNTKAFRDACKA 256

Query: 275 MKATGKPTVALFLGYT 290
            +A  KP +AL LG +
Sbjct: 257 ARAASKPVIALKLGAS 272


>UniRef50_C3XDZ9 Putative uncharacterized protein n=1 Tax=Helicobacter bilis ATCC
           43879 RepID=C3XDZ9_9HELI
          Length = 650

 Score = 62.8 bits (151), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 36/232 (15%), Positives = 84/232 (36%), Gaps = 16/232 (6%)

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
           N+  V + +          I +  +    +L   +     L   + + S  +   D + A
Sbjct: 231 NERVVIVGASTEKGKTGYTIAKNAQSFKGELLYVNAKGGELFGKKLYKSVSEIEGDIDTA 290

Query: 122 LISVAGEYAAELANQALDRNL-NVMMFSDNV--TLED--EIQLKTRAREKGLLVMGPDCG 176
           +I +  ++     ++ + + L N+++ +     +  D  E ++   A      V+GP+C 
Sbjct: 291 VIVIGAKFVIPTIHELVKKGLKNLIIITAGFKESGHDAEEEEIGRLAATHNFNVIGPNCL 350

Query: 177 TSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
                   L       ++ +G+   +  SG  +  L  + A  G G +H I +G      
Sbjct: 351 GFYANEEKLNITFGTGMVHDGSHAFVSQSGAVLASLMDRAAELGLGFSHLISVG------ 404

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVAL 285
               + +   + ML+  +  E +A   +    A    +  +++   KP    
Sbjct: 405 NAVDLRSAEIIPMLNNAKSCESIALYLE--GVARGKSLCESIRNCNKPIYLF 454


>UniRef50_B5JNQ5 Acetyltransferase, GNAT family n=1 Tax=Verrucomicrobiae bacterium
           DG1235 RepID=B5JNQ5_9BACT
          Length = 892

 Score = 62.8 bits (151), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 69/408 (16%), Positives = 128/408 (31%), Gaps = 62/408 (15%)

Query: 112 CQKLPD-ANLALISVAGEYAAELANQALDRNLNVMMFS----DNVTLEDEIQLKTR---A 163
             K+PD  +LA+I+        L  +     +   +        +  + E+ L+     A
Sbjct: 64  LSKIPDPIDLAIIATPPASVPALIEECGKCGIGAAVIVSAGFQEIGKKGEVLLRQVIRNA 123

Query: 164 REKGLLVMGPDCGTSMIAGTPL--AFANVMP-EGNIGVIGASGTGIQELCSQIALAGEGI 220
           ++  + ++GP+C   +     L  +F++ M   G +  I  SG     +         G 
Sbjct: 124 KKAKVRLIGPNCLGFIRPPIGLNASFSSAMALPGRLAFISQSGALCTAVLDWSIRENVGF 183

Query: 221 THAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGK 280
           +H I +G       +  I     ++ L  D  +  +    +   +A R    +      K
Sbjct: 184 SHFISIG------SMADIGYHDLIDYLGQDPNTSSILIYMESIKDARRFISASRSIGKTK 237

Query: 281 PTVALFLGYTPAVARDENVWFAS-----SLDEAARLACLLSRVTARRN----------AI 325
           P V L +G +   A   +    S     +L EA      ++RV   +             
Sbjct: 238 PIVVLKVGRSSEGAAAVSSHTGSLSGDDTLYEALFKRSGIARVDTVKELFNIAQNLSTQS 297

Query: 326 APVSSGFICGLYTG--GTLAAEAAGLLAGHLGVEADDTHQHGMMLD----ADSHQIIDLG 379
            P +   +     G  G LA +A     G +   +  T      +     +  + +  LG
Sbjct: 298 LPQNDRLLIITNAGGPGILATDAHIKFNGQMASLSRSTIDKLNQVLPPAWSHGNPVDILG 357

Query: 380 DDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASL-VSAWQKA 438
           D   +  +    I        + +  A   + VL             P A        K 
Sbjct: 358 DSGVSRYKQAFEI-------CLQEENADGILVVL------------TPQAMTNAYQIGKE 398

Query: 439 CAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEAT 486
             A         +A+  G         +    LE+ G+ V  S  EA 
Sbjct: 399 IGALAKTTGKTVLASFMGAAE----VERGTRVLEEMGVPVYDSPEEAV 442


>UniRef50_C6C1C2 CoA-binding domain protein n=4 Tax=Desulfovibrio RepID=C6C1C2_DESAD
          Length = 708

 Score = 62.4 bits (150), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 42/197 (21%), Positives = 80/197 (40%), Gaps = 20/197 (10%)

Query: 116 PDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLED------EIQLKTRAREKGL 168
              +LA+++V  +    +  + L+  ++ V++ +      D      E+QL   A E G+
Sbjct: 63  TPVDLAVVAVPRDLVLGIFKELLELGVSSVVVITAGFKEVDHEGWLLEVQLAKLAEEHGV 122

Query: 169 LVMGPDCGTSM--IAGTPLAFANVMP-EGNIGVIGASGTGIQELCSQIALAG--EGITHA 223
            ++GP+C   +    G   +FA   P  G++G    SG     +       G   G +  
Sbjct: 123 NLLGPNCLGVINSRGGVNASFATGNPLPGSMGFFSQSGALC--VAVLDWALGEKVGFSKF 180

Query: 224 IGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTV 283
           I LG + +  E       + +E L  D +++V+    +   +        A  +  KP +
Sbjct: 181 ISLGNKAVINE------ASMIEYLGNDPETKVILGYVENIEDGREFMAQAAKVSMKKPIL 234

Query: 284 ALFLGYTPAVARDENVW 300
            +  G TPA AR  +  
Sbjct: 235 MMKAGTTPAGARAASSH 251


>UniRef50_B2TEE7 CoA-binding domain protein n=1 Tax=Burkholderia phytofirmans PsJN
           RepID=B2TEE7_BURPP
          Length = 750

 Score = 62.4 bits (150), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 49/244 (20%), Positives = 86/244 (35%), Gaps = 22/244 (9%)

Query: 110 SACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLED------EIQLKTR 162
           +A    PD  LALI VA     ++  Q  ++ +   +++S             + +    
Sbjct: 71  AALPSTPD--LALILVAARRVPDMLRQCGEKGVGFAIVYSSGFAEAGEAGAALQRECADI 128

Query: 163 AREKGLLVMGPDC------GTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALA 216
           A+  G+ V+GP+C      G ++ AG    F      G + +I  SG     L       
Sbjct: 129 AKAHGIRVIGPNCQGFVSTGANVYAGFGAPFGVAYRRGGLSLISQSGGFGCALLLMADEL 188

Query: 217 GEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVR-LKIVNAM 275
           G G+ H I  G          +S L  +    AD  + ++A   +   +A R + + N  
Sbjct: 189 GIGLRHFITTGNE------ADVSLLDLVNACIADPHTSLIATYIEGLKDAGRLVDMANRA 242

Query: 276 KATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICG 335
              GKP +A  +G T   A+      A+    +A       +      +       +   
Sbjct: 243 LDAGKPLLAWKVGNTADGAKAAASHTANLGGASALYRTAFRQTGVIEVSDVADLGDYARA 302

Query: 336 LYTG 339
              G
Sbjct: 303 FEAG 306


>UniRef50_UPI0000E48CED PREDICTED: similar to ENSANGP00000012364 n=1 Tax=Strongylocentrotus
           purpuratus RepID=UPI0000E48CED
          Length = 588

 Score = 62.4 bits (150), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 35/182 (19%), Positives = 62/182 (34%), Gaps = 25/182 (13%)

Query: 144 VMMFSDNVTLEDEIQLKTRAREKGLLVMGPD-----------------C---GTSMIAGT 183
           ++M   ++  +   +L   A  K +L++GP                  C   G       
Sbjct: 336 ILMMVGHINEQQTRELIGLASRKRVLMIGPSSFKHGLQVNVIKPGSFRCNLFGDIGGPLP 395

Query: 184 PLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTA 243
            L    +  +G++  +  SG    ELC  IA   +GI   I LGG   +    G   +  
Sbjct: 396 DLVELKLYRQGSVVYLSRSGGLSTELCVSIARNSDGIYMGIALGGGRYT----GSGIMDH 451

Query: 244 LEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKAT-GKPTVALFLGYTPAVARDENVWFA 302
           +  L  +   +    + +              K T  KP +A  +G    + + E  +F 
Sbjct: 452 IRFLQDNHAVKCFILIGEVGGLEEYEVCEALKKGTITKPVIAFCIGTCTDLYKQEPAYFG 511

Query: 303 SS 304
            S
Sbjct: 512 HS 513


>UniRef50_A2SRS8 CoA-binding domain protein n=2 Tax=Methanomicrobiales
           RepID=A2SRS8_METLZ
          Length = 707

 Score = 62.0 bits (149), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 32/248 (12%), Positives = 85/248 (34%), Gaps = 19/248 (7%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
           VA+   + D      A+ + + +   ++   +     +  V+ + +        ++ +I+
Sbjct: 267 VAVIGASDDPTKMGYAVFRNILQFPGKVYPVNNKRDEIQGVKCYPTLSDIPGHVDMVVIT 326

Query: 125 VAGEYAAELANQALDRNLNV-MMFSDNVTLEDE------IQLKTRAREKGLLVMGPDCGT 177
           V  +    + ++   + + + ++ +      DE       ++   A+  G+ ++GP+C  
Sbjct: 327 VPAQLVPAIMSECGLKGVKMAVVITAGFKEMDEDGRALETRMVEIAKNYGIRIVGPNCLG 386

Query: 178 SMIAGTPLAFANVMP---EGNIGVIGASGTGIQELCSQIALAG--EGITHAIGLGGRDLS 232
            ++    L    V      G+I  I  SG  +  +       G   G +  + +G +   
Sbjct: 387 LILPPFKLDTTYVSTSPLPGDIAFISQSGAIVNAVVGISLSEGSEMGYSEVVSVGNQ--- 443

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                +  L  +   + D  ++ +    +     V    +       KP VA+  G +  
Sbjct: 444 ---CDLDFLDYMSYAARDPHTKSIILYVEEIKNGVAFMEMAKEITQTKPIVAIKAGSSKR 500

Query: 293 VARDENVW 300
                   
Sbjct: 501 GQAAAASH 508


>UniRef50_Q13HH2 Putative CoA ligase n=1 Tax=Burkholderia xenovorans LB400
           RepID=Q13HH2_BURXL
          Length = 708

 Score = 62.0 bits (149), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 40/293 (13%), Positives = 98/293 (33%), Gaps = 43/293 (14%)

Query: 66  VAIRSEAADAGIAQAIMQQLEE--ALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALI 123
           +AI   +     ++  +Q+L++     ++   +  +  +   R   +        ++AL+
Sbjct: 15  MAIIGASERNFYSRNALQRLQDCGYAGKVHLVNPGTSEVFGKRCHANVKDIGESIDMALV 74

Query: 124 SVAGEYAAELANQALDRNLNVMMF--------SDNVTLEDEIQLKTRAREKGLLVMGPDC 175
            V            ++      +          D V L  + +L     E  + + GP C
Sbjct: 75  VVPRTAVIGALRDCVEAGAKAAVVVSTGFGESHDAVGLALQRELSEFLDEHPIALCGPSC 134

Query: 176 GTS--MIAGT---PLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
                MI G           +  G+IG++  SG  +       +    G ++ +  G   
Sbjct: 135 LGVVNMIDGFQAFGGHPGTEILPGSIGLVSQSGANVHSYIGAASARNLGFSYVVSSGNE- 193

Query: 231 LSREVGGISALTALEMLSADEKSEVL-AFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
                 G+ A   ++    D  ++V+ A++    +    +++        KP + + +G 
Sbjct: 194 -----AGMDATDYIDCFLRDPDTKVVCAYIESFKSSDALIRVAEQALKVSKPLIVIKIGR 248

Query: 290 TPAVA---------------------RDENVWFASSLDEAARLACLLSRVTAR 321
           +P+                       R   +  A++++E+   AC+ +     
Sbjct: 249 SPSAVRAALAHTGAMTGPDHYFDTLFRQYGIIRANTIEESLDRACIFASSQEA 301


>UniRef50_Q4TGD5 Chromosome undetermined SCAF3766, whole genome shotgun sequence.
           (Fragment) n=1 Tax=Tetraodon nigroviridis
           RepID=Q4TGD5_TETNG
          Length = 328

 Score = 62.0 bits (149), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 22/151 (14%), Positives = 53/151 (35%), Gaps = 17/151 (11%)

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           I +        A +    +++ + + ++ +      ++   A EKG+ ++GP     +  
Sbjct: 120 ILIPVYKNMSEAMKK-HPDIHTIAIIAEGIPEAFTRKIIKAADEKGVTIIGPATVGGIKP 178

Query: 182 G------TPLAFANV-----MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
           G      T     N+        G++  +  SG    EL + I+   +G+   + +GG  
Sbjct: 179 GCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNELNNIISRTTDGVFEGVAIGGD- 237

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSK 261
                 G      +         E++  + +
Sbjct: 238 ---RYPGSVFTDHVLRYQDTPGVEMIVVLGE 265


>UniRef50_Q7MRU7 Putative uncharacterized protein n=1 Tax=Wolinella succinogenes
           RepID=Q7MRU7_WOLSU
          Length = 644

 Score = 61.6 bits (148), Expect = 7e-08,   Method: Composition-based stats.
 Identities = 40/241 (16%), Positives = 92/241 (38%), Gaps = 17/241 (7%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
           VAI   + D      AI +       +L   +     L     + +      D ++A++ 
Sbjct: 230 VAIIGASTDESKVGYAIAKNAASFQGELYYVNPKGGELFGRPLFQNVEAIPGDVDMAVLV 289

Query: 125 VAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGPDCGT-- 177
           +          + + +NL  ++     F ++   EDE+++   A++    V+GP+C    
Sbjct: 290 IPVSSVIPTIEKLVLKNLKNLVIITAGFKESGNEEDELKIAELAKKHNFNVIGPNCLGYY 349

Query: 178 SMIAGTPLAFANV-MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVG 236
           +  +   L F +  + +GN+ +I  SG  +  L  +      G +H I  G       + 
Sbjct: 350 NAQSDLNLTFGSSNVHKGNLALISQSGAVLASLMDKAYSGNVGFSHLISAG------NMV 403

Query: 237 GISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARD 296
            ++    ++ML AD   E ++  ++        + + +++ + K       G +    + 
Sbjct: 404 DLNFSEMVDMLVADPACEAISVYAE--GIKNGKRFLRSIRRSHKKIYVFKTGKSEESKKA 461

Query: 297 E 297
            
Sbjct: 462 A 462


>UniRef50_C5EFZ7 Putative uncharacterized protein n=1 Tax=Clostridiales bacterium
           1_7_47FAA RepID=C5EFZ7_9FIRM
          Length = 693

 Score = 61.6 bits (148), Expect = 7e-08,   Method: Composition-based stats.
 Identities = 54/255 (21%), Positives = 90/255 (35%), Gaps = 33/255 (12%)

Query: 66  VAIRSEAADAG---IAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +AI   +  AG          +  + L QL   +     +   R + S  +   D +L +
Sbjct: 12  IAIVGASEKAGFGGDTTRNYLKFSKNLDQLYLVNPGRDTIFGRRAYHSLSEIEGDVDLVI 71

Query: 123 ISVAGEYAAELANQAL--DRNLNVMMFSDNVTL-----EDEIQLKTRAREKGLLVMGPDC 175
           +    +    L  +A   +    V+  S    +     E + +L   A   G+ VMGP+C
Sbjct: 72  LCTPQKTIIPLLEEAAGKNCGGAVVFASGYGEVGPEGRERQRELVEAADRLGIAVMGPNC 131

Query: 176 GT--SMIAGTPLAFANVM----PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
               + + G   AFA ++      GNIG+I  SG   Q +   +     G +H I  G  
Sbjct: 132 AGFANFVDGI-FAFAFLVEERERGGNIGMISQSG---QIVLGGLDSPNMGFSHVISSG-- 185

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAF----VSKPPAEAVRLKIVNAMKATGKPTVAL 285
                   +     L+ L  DE ++V+A     V+KP      +          KP V L
Sbjct: 186 ----NSCNVKVEDYLDFLVDDEDTKVVAAYMEGVTKP---EKLVAAFQKAALKKKPVVVL 238

Query: 286 FLGYTPAVARDENVW 300
             G +          
Sbjct: 239 KTGRSSKSQELAKSH 253


>UniRef50_Q58010 Uncharacterized protein MJ0590 n=11 Tax=Methanococcales
           RepID=Y590_METJA
          Length = 704

 Score = 61.6 bits (148), Expect = 7e-08,   Method: Composition-based stats.
 Identities = 53/268 (19%), Positives = 99/268 (36%), Gaps = 18/268 (6%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
           VAI   +   G    AIM+ L++   ++   +     +  ++ + S      D +LA+I 
Sbjct: 17  VAIIGASKTEGKVGYAIMKNLKDFNGKIYPINPKYDEIFGIKCYKSVLDVEDDIDLAVIV 76

Query: 125 VAGEYAAELANQALDRNLN--VMM---FSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSM 179
           V      ++  +   + +   V++   FS+    E E ++K  A+   + ++GP+C   M
Sbjct: 77  VPNIVVPKVLEECGKKGVKGAVIITAGFSEVGNYELENKIKEIAKRYNIRIIGPNCLGIM 136

Query: 180 IAGTPL--AFANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR-DLSREV 235
                L   FA V P  G + +I  SG  +  +     L   G +  + +G + D+    
Sbjct: 137 NTHINLNATFAKVFPPKGGVSIISQSGAVLNAILDIAPLLNIGFSKVVSIGNKADIQES- 195

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVAR 295
                   LE    DE ++++    +   +  R   V    +  KP +AL  G T    +
Sbjct: 196 ------DLLEYFLDDEDTKIVVLYIE-GLKDKRFLKVAKKLSKKKPIIALKSGRTEVGKK 248

Query: 296 DENVWFASSLDEAARLACLLSRVTARRN 323
                  S   E              R 
Sbjct: 249 AAKSHTGSLAGEDVIYEAAFKEAGIIRA 276


>UniRef50_A4J695 CoA-binding domain protein n=6 Tax=Peptococcaceae
           RepID=A4J695_DESRM
          Length = 701

 Score = 61.6 bits (148), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 41/228 (17%), Positives = 86/228 (37%), Gaps = 21/228 (9%)

Query: 110 SACQKLP-DANLALISVAGEYAAELANQALDRNL-NVMMFSDNVT------LEDEIQLKT 161
           S   ++P   +LA++ V      E+  +    ++ N ++ S   +      L+ E +L +
Sbjct: 59  STLSEIPNQIDLAVVCVPALNCPEVLEECGKHSIKNAVVISSYFSEIGPEGLQLEKRLVS 118

Query: 162 RAREKGLLVMGPDCGTSMIAGTPLAFANVMP----EGNIGVIGASGTGIQELCSQIALAG 217
             ++ G+ ++GP+C   M    PL  A++ P     G+IG I  SG  +  +        
Sbjct: 119 ICKKYGIHLLGPNCEGMMDTRIPLN-ASISPSFPKRGDIGFISQSGAMLLSIMDWSRTVS 177

Query: 218 EGITHAIGLGGR-DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMK 276
            G +    LG + D+S           ++ L+ D  ++V+    +   +      V +  
Sbjct: 178 LGFSRVFSLGNKADVSE-------TDLIKCLANDPLTKVILCYIEDVQKGKEFLEVASKA 230

Query: 277 ATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNA 324
              KP + L  G + A     +    + +          ++    R  
Sbjct: 231 TKKKPVIILKSGTSQAGTLAASSHTGALVGSDLAYETAFTQAGILRAR 278


>UniRef50_Q2YZQ4 Acyl-CoA synthetase (NDP forming) n=1 Tax=uncultured delta
           proteobacterium RepID=Q2YZQ4_9DELT
          Length = 504

 Score = 61.6 bits (148), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 40/227 (17%), Positives = 82/227 (36%), Gaps = 19/227 (8%)

Query: 110 SACQKLPD-ANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQLKTR----- 162
            + + +PD  +  + ++   Y  +L   A  + +  +  F+   +  + ++ K       
Sbjct: 87  KSVKDIPDKIDFVISAIPSRYTPQLMADAAQKGVKAIHFFTSGFSEIENVEGKHLQADII 146

Query: 163 --AREKGLLVMGPDCGTSMIAGTPLAFANVMPE--GNIGVIGASGTGIQELCSQIALAGE 218
             A+  G+ V+GP+C         L+F     +  G + +I  SG        +    G 
Sbjct: 147 ARAKAGGIRVVGPNCLGLYCPSGGLSFNADFDKTSGPVAMISQSGGNAAHCVQEGNDRGV 206

Query: 219 GITHAIGLG-GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKA 277
             +  I +G G DL+           LE L+ DE+++++    +   E  R         
Sbjct: 207 LFSKVISMGNGADLNES-------DYLEYLTHDEETKIITAYIEGVREGPRFLRALKSAT 259

Query: 278 TGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNA 324
             KP + L +G + + A       A+           L +    R +
Sbjct: 260 KSKPVIILKVGTSVSGAEAAVSHTAAMAGSNQVWEGALRQAGVIRTS 306


>UniRef50_C6C0V7 CoA-binding domain protein n=2 Tax=Desulfovibrio RepID=C6C0V7_DESAD
          Length = 702

 Score = 61.2 bits (147), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 47/273 (17%), Positives = 93/273 (34%), Gaps = 24/273 (8%)

Query: 65  CVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
            + I ++  D                ++   +G    +  +  + S  Q     +LALI 
Sbjct: 18  VIGISADPQDKASIITANLLASGYKGKIFPVNGEGAEVHGLGAFSSVSQLPRGIDLALIC 77

Query: 125 VAGEYAAELANQALDRNLNVMMFSDNVTLED-----------EIQLKTRAREKGLLVMGP 173
           +      + A QA+D    +++ +  VT              E +L   A+   ++++GP
Sbjct: 78  LPP----DEAIQAIDDLSEILVRAAVVTSGGFGETGREGYRLERELARTAKNHDMIILGP 133

Query: 174 DCGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
           +C   M     +  +   +   +GNI  +  SG             G G +  I LG   
Sbjct: 134 NCMGLMNTALGMNASLDPDFTLKGNIAFLSQSGAMCSTALDWANSEGVGFSKFISLG--- 190

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
            ++ V G + +  L  L+ DE ++V+    +   +              KP + L  G T
Sbjct: 191 -NKAVLGEATM--LNYLANDEDTKVIVGYCETLKDGQDFLRTAYDTTFKKPLILLRAGET 247

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARRN 323
           P+ AR  +                 ++    + 
Sbjct: 248 PSGARAASAHAGHLTGATTAYNAAFNQTGVMQA 280


>UniRef50_D1A2N2 CoA-binding domain protein n=2 Tax=Actinomycetales
           RepID=D1A2N2_THECD
          Length = 690

 Score = 61.2 bits (147), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 40/193 (20%), Positives = 80/193 (41%), Gaps = 15/193 (7%)

Query: 109 DSACQKLPDAN-LALISVAGEYAAELANQALDRNLNVMM-FSDNVTLED-----EIQLKT 161
             +  +LP A  L +++        + ++AL   +   +  + ++   +     E +L  
Sbjct: 57  ARSLSELPSAPELVVLTAPARTIPAVIDEALALGVKGFLGITAHIDAANGEAGLERRLAE 116

Query: 162 RAREKGLLVMGPDCGTSMIAGTPLAFA-NVMPEGNIGVIGASGTGIQELCSQIALAGEGI 220
           R R  G  ++GP+C     AG+ L  A      G+I ++  SG    EL    A AG G+
Sbjct: 117 RIRRAGARIVGPNCLGLYDAGSELELAWGTFVPGSIAIVSQSGQLGLELAGLAAHAGLGV 176

Query: 221 THAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAF-VSKPPAEAVRLKIVNAMKATG 279
           +  + +G +        ++A   LE L + E +  +   +    A      ++  ++  G
Sbjct: 177 SRFVSIGNQ------VDVTAAELLEDLISHETTRTVVLYLENFGAGRELAAVMARLRQAG 230

Query: 280 KPTVALFLGYTPA 292
           K  + L +G + A
Sbjct: 231 KHVIVLTVGASDA 243


>UniRef50_A1RX15 CoA-binding domain protein n=2 Tax=Archaea RepID=A1RX15_THEPD
          Length = 508

 Score = 61.2 bits (147), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 44/259 (16%), Positives = 85/259 (32%), Gaps = 34/259 (13%)

Query: 65  CVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQV------RRWDSACQKLPDA 118
            V + +   +      I + L E  K+    +       +       + + S      + 
Sbjct: 15  VVVVGASREEEKPGHVIFRVLLENRKKGLLKAPVYGVNPKADYILGEKVFPSVKDIPGEV 74

Query: 119 NLALISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGP 173
           +LA+I +  E+          + +   +     FS+    + E ++   A++ G+ ++GP
Sbjct: 75  DLAVIVIPAEHVKRAIEDLGVKGIKAAIIISAGFSEIGRSDLEREVAETAKKHGIRIIGP 134

Query: 174 DCGTSMIA--GTPLAFA-------------NVMPE--GNIGVIGASGTGIQELCSQIALA 216
           +C        G    F              N      G + +I  SG         +   
Sbjct: 135 NCIGVYSPWSGVDTIFLPYTKVLEDGREVLNAPRPSKGFVALISQSGAVGTAALDYMYGE 194

Query: 217 GEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMK 276
           G G++H + +G +    EV        +E L  D+++ V+    +          V    
Sbjct: 195 GIGLSHFVSIGNKADVDEV------ELVEYLGGDDRTRVILLYLENIKRGREFIEVAGKV 248

Query: 277 ATGKPTVALFLGYTPAVAR 295
              KP V L  G T A  R
Sbjct: 249 TLKKPVVVLKAGRTSAGRR 267


>UniRef50_D2R7V1 CoA-binding domain protein n=1 Tax=Pirellula staleyi DSM 6068
           RepID=D2R7V1_9PLAN
          Length = 911

 Score = 61.2 bits (147), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 49/250 (19%), Positives = 91/250 (36%), Gaps = 20/250 (8%)

Query: 65  CVAIRSEAADAGIA-QAIMQQLEEALKQLAQGSGSSQALTQVRRWD-SACQKLPDA-NLA 121
            VA+   +   G     +++ L E          ++   T           +LP+  +L 
Sbjct: 14  VVAVVGASDQPGKVGHTLLKNLVEHGYTGRVYPINATRDTVQGMTAYRDLVQLPEKPDLV 73

Query: 122 LISVAGEYAAELANQALDRNL-NVMMFSDNV------TLEDEIQLKTRAREK-GLLVMGP 173
           +I        +L  Q     +  V++ S          ++ E Q++   +   GL V+GP
Sbjct: 74  VICTPSTTVPKLIEQCGQLGIMGVVIISAGFREVGPAGMQLEQQIREIQKSYPGLRVLGP 133

Query: 174 DCGTSMIAGTPLA--FANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
           +C   ++    L+  FA  MP  G +  +  SG     +      AG G +H + LG   
Sbjct: 134 NCLGFLVPDLKLSASFARGMPKPGRLAFLSQSGALCTAVLDWALDAGIGFSHFVSLG--- 190

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
            +    G+     L+ L+AD  ++ +    +  + A          A+ KP VA   G  
Sbjct: 191 -NMLDVGLD--DMLDYLAADPTTDAVILYVESISRAREFMSAARAFASHKPIVAYKAGRF 247

Query: 291 PAVARDENVW 300
              A+  +  
Sbjct: 248 SDSAKAASSH 257


>UniRef50_Q3AFE8 Acetyl-CoA synthase n=1 Tax=Carboxydothermus hydrogenoformans
           Z-2901 RepID=Q3AFE8_CARHZ
          Length = 716

 Score = 61.2 bits (147), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 37/194 (19%), Positives = 71/194 (36%), Gaps = 20/194 (10%)

Query: 119 NLALISVAGEYAAELANQALDRNLN-VMMFS--------DNVTLEDEIQLKTRAREKGLL 169
           +LA+I +  E A     +A +  +   ++ S        +   LE+E  +K  A +  + 
Sbjct: 80  DLAVIVLPAEKAVVALKEAAEAGVKSAVVISGGFKETGNEGALLEEE--IKKIALDFEMP 137

Query: 170 VMGPDCGTSMIAGTPL--AFANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGL 226
           V+GP+C   +     L   F    P +G I  +  SG  +  +         G ++ I +
Sbjct: 138 VLGPNCVGIVNNNLQLNATFLRTAPLKGEIAFVSQSGAILSTVLEWSLKEDLGFSYMISM 197

Query: 227 GGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALF 286
           G + +  E         L  ++ D  + V+    +   E           +  KP V   
Sbjct: 198 GNKAVLNE------ADFLPAIANDPGTAVILLYIEDVVEGSSFLKKAYEASLLKPVVVFK 251

Query: 287 LGYTPAVARDENVW 300
            G + A A+  +  
Sbjct: 252 AGISTAGAKAASSH 265


>UniRef50_C5C5J4 GCN5-related protein N-acetyltransferase n=3 Tax=Micrococcineae
           RepID=C5C5J4_BEUC1
          Length = 907

 Score = 61.2 bits (147), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 90/454 (19%), Positives = 148/454 (32%), Gaps = 74/454 (16%)

Query: 55  DFNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQK 114
                TP D+      EA  A      +  + E L+    G             D A   
Sbjct: 210 VVGGGTPEDVLAVRALEAVLASEFTGAVTCVGEVLR----GPAEGTRARWHASIDGAIGD 265

Query: 115 LPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQ--------LKTRARE 165
              A+LA++++      +L  +      + V++ SD     D  +        L   AR 
Sbjct: 266 GRGADLAVVALPPAAVVDLLGRLTPLGTHGVVVLSDGFGTGDPTRPADVTQADLVAAART 325

Query: 166 KGLLVMGPDCGTSMIAGTPLAFANVM------PEGNIGVIGASGTGIQELCSQIALAGEG 219
           +G+ V+GP     +  G      N          G++G+   SG     L + +     G
Sbjct: 326 RGVRVVGPRSYGILAQGEA-GRMNATLWPRAARVGDVGLFCQSGAAAAALAASVEGRRLG 384

Query: 220 ITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATG 279
           ++  +  G R    +V G     A++   +DE+++V A   +      +   V    +  
Sbjct: 385 LSTFLSAGHR---ADVSGN---DAMQFWQSDERTKVAALYLESFGNPRKFSRVARRLSAQ 438

Query: 280 KPTVALFLGYTPAVARDENVWFAS-----SLDEAARLACLLSR---------VTARRNAI 325
            P VAL  G    V    ++   +     + +E  R A +L+           T      
Sbjct: 439 TPVVALVSGQRGQVVAPGHLVATTGAPRRTTEEMLRQAGVLAAQTTHELLDMATVLSAQP 498

Query: 326 APVSSGFICGLYTGGTLAAEAAGLLAGHLG---------VEADDTHQHGMMLDADSHQII 376
            P     +  L   GTLAA    L+   LG           A      G   +A    ++
Sbjct: 499 LPAGER-VAVLTNSGTLAA----LVVDALGARGLEVAGEPVALAPLADGAGYEAAVRTLL 553

Query: 377 DLGD----DFYTVGRPHPM--IDPTL--RNQLIADLGAKPQVRVLL------------LD 416
           D  D    D   V    P+   DP +      +A   A+P V V+L              
Sbjct: 554 DGADRGEWDSAVVAYVPPLGERDPAVGEALARLAHESARPVVGVVLGLRGLTPELTTQGV 613

Query: 417 VVIGFGATADPAASLVSAWQKACAARLDNQPLYA 450
            V  +G   D   +L +A   A   R D+  L  
Sbjct: 614 TVPAYGTAEDAVHALAAAHTYARWRRTDHGTLVV 647


>UniRef50_Q9NAT4 Acetyl-CoA synthetase n=3 Tax=Entamoeba RepID=Q9NAT4_ENTHI
          Length = 713

 Score = 61.2 bits (147), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 32/189 (16%), Positives = 72/189 (38%), Gaps = 16/189 (8%)

Query: 119 NLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDE------IQLKTRAREKGLLVM 171
           +LA+I++  ++   +  +  +  +  +++ +       E      I+++   ++  + ++
Sbjct: 67  DLAVIAIPAKFVPGVCIECGEAGVKGLIIITAGFAEAGEEGKKMCIEIQATCQKYNMRMI 126

Query: 172 GPDCGTSMIA--GTPLAFANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
           GP+C   +    G   +FA+VMPE G +  I  SG     +    A    G ++ + +G 
Sbjct: 127 GPNCLGIINPRDGVNASFASVMPEAGGVAFISQSGALCTAILDWAANQHVGFSYFVSIGS 186

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG 288
                           E  + D K   +    +   +A +  +     A  KP + L  G
Sbjct: 187 S------IDTDYADLFEFFAKDPKVTSILMYIESIKDAKKFVLRAREFAADKPIILLKAG 240

Query: 289 YTPAVARDE 297
            +   A   
Sbjct: 241 KSSEGAAAA 249


>UniRef50_A0LG54 CoA-binding domain protein n=1 Tax=Syntrophobacter fumaroxidans
           MPOB RepID=A0LG54_SYNFM
          Length = 682

 Score = 61.2 bits (147), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 57/297 (19%), Positives = 113/297 (38%), Gaps = 44/297 (14%)

Query: 118 ANLALISVAGEYAAELANQALDRNL-NVMMFSDNVTLEDEI------QLKTRAREKGLLV 170
            +LA I V      E+  Q  ++ +  V++ S       E       +++       + +
Sbjct: 65  IDLATILVPAPAVPEVLRQCGEKGIPRVIVQSAGFRELGEERLELEGKVRDLLEHYRMRM 124

Query: 171 MGPDCGTSMIAGTPLA-----FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIG 225
           +GP+C   +   T LA      A  +  G I +I  SG     + + +     G++    
Sbjct: 125 IGPNCLGVINRRTGLAVPFFPLAANVGAGPISIISQSGGVGAMMVNLLEAENLGLSRFAS 184

Query: 226 LGGR-DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
           +G + D+S           LE  + D ++E++    +  A+    K++   + T KP + 
Sbjct: 185 VGNKLDVSEN-------DLLEYFARDPETEMILCYLEGIAD--GRKLMRITRETPKPVIV 235

Query: 285 LFL-----GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLY-- 337
                   G   A +   ++     + +AA     + RV  +R A+  + +  +  L   
Sbjct: 236 HKSNTGKCGAAIARSHSASLSSDDRVVDAAFRQSGIIRVREQREAVEVLKAYSLPPLAGN 295

Query: 338 -------TGG--TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQI-----IDLGD 380
                  +GG   LAA+AA      L    +D  Q  +   + ++ I     +D+GD
Sbjct: 296 RLAVISRSGGHAVLAADAAEEYGFVLPPYPEDFFQL-IREQSRANVISFHNPLDVGD 351


>UniRef50_Q39YX3 CoA-binding protein n=1 Tax=Geobacter metallireducens GS-15
           RepID=Q39YX3_GEOMG
          Length = 909

 Score = 61.2 bits (147), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 39/294 (13%), Positives = 84/294 (28%), Gaps = 37/294 (12%)

Query: 102 LTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN---VMMFSDNVTLEDEIQ 158
           +          +     +  ++ +     +   ++   RN+N   +++ ++ V+  D   
Sbjct: 72  IPVFGSISDVIRAGIHFDTGVVYLPPSAVSHAVSEMCARNVNLKRIVIVTEKVSARDSRL 131

Query: 159 LKTRAREKGLLVMGPDC------------GTSMIAGTPLAFANVMPEGNIGVIGASGTGI 206
           ++   +   + V+G +             G ++    P   A  + +G++ +   SG   
Sbjct: 132 IRYGCQNAKVDVIGANTLGIANSWDQVRIGGALGGDVP---AQSLRKGSVAIYSNSGNFS 188

Query: 207 QELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPA-- 264
             +   +  AG G +  +  G           +    L     D +++ +    +P    
Sbjct: 189 TTISEYLKTAGFGTSTILSSG----KDVYIHFALAEFLYCAENDPRTKAIVVYVEPGGYY 244

Query: 265 -EAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW---FASSLDEAARLACLLS---R 317
            +     I        KP +A   G                A S D+A            
Sbjct: 245 EKQALDWISEGRFKLTKPIIACVTGRWKKNLTRSCGHAGAMAGSGDDAEAKEIWFDDFFG 304

Query: 318 VTARRNAIAPVSSGFICGLYTGGTLAA--EAAGLLAGHLGVEADDTHQHGMMLD 369
           V         VS   I       T+    EA       +G   D      + L 
Sbjct: 305 VPVFDPERPEVSKRGIRIR----TIQDVPEAVTACMELMGENPDFPSTGDLSLK 354


>UniRef50_C5A641 Acetyl-CoA synthetase (ADP forming), alpha chain (AcdA) n=18
           Tax=Euryarchaeota RepID=C5A641_THEGJ
          Length = 463

 Score = 60.8 bits (146), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 40/243 (16%), Positives = 82/243 (33%), Gaps = 20/243 (8%)

Query: 106 RRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVM-MFSDNV----TLED--EIQ 158
           + + S      + ++A+I V  ++  ++  +   + + V+ + S             E Q
Sbjct: 62  KSYKSILDVPDEVDMAVIVVPAKFVPQVVEECGKKGVKVLPIISSGFGELGPEGKKIEQQ 121

Query: 159 LKTRAREKGLLVMGPDCGTSMIAGTPL----AFANVMPEGNIGVIGASGTGIQELCSQIA 214
           L   A + G+ ++GP+    +     L       +VMP G + +I  SG     L     
Sbjct: 122 LVETAHKYGMRILGPNIFGVVYTPEKLNATFGPTDVMP-GKLALISQSGALGIALMGWTI 180

Query: 215 LAGEGITHAIGLGGR-DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVN 273
           L   G++  + +G + D+            LE    DE ++ +    +   +  R   V 
Sbjct: 181 LEKVGLSAVVSIGNKSDIDDA-------DLLEYFETDENTKAILIYMEGVKDGRRFMEVA 233

Query: 274 AMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFI 333
              +  KP V +  G +   A+       S             +    R      +  + 
Sbjct: 234 KKVSKVKPIVIIKAGRSERGAKAAASHTGSLAGSDKIYDAAFKQAGIIRALTIGEAFDYA 293

Query: 334 CGL 336
             L
Sbjct: 294 RTL 296


>UniRef50_C0QHK1 SucC2 n=1 Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QHK1_DESAH
          Length = 709

 Score = 60.8 bits (146), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 46/252 (18%), Positives = 90/252 (35%), Gaps = 30/252 (11%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMF---------S 148
              ++  +  +DS      + +LALI+   +    L  +  ++ +   +          +
Sbjct: 46  REDSVLGIPCYDSITSIDQEVDLALITTPAKTIPALLKECGEKKVAGAVIVAGGFRELGT 105

Query: 149 DNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANV--MPEGNIGVIGASG--- 203
           +   L  E  +   A+E G+ ++GP+    +   + +    +   P G I +I  SG   
Sbjct: 106 EGKAL--EALVVETAKESGVRIIGPNTSGMINMKSNMNLVGIKNAPRGGIALICQSGNMA 163

Query: 204 -TGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKP 262
            T I E   +      G T+ IG+G          I     LE L  D +++ +    + 
Sbjct: 164 LTLITEAMIRKHE---GFTYYIGVGNE------ADIKFHEYLEFLRNDPETKSILMYVEG 214

Query: 263 PAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFA--SSLDEAARLACLLSRVTA 320
            ++  +           KP V L  G +    R         + + E A  A   + +T 
Sbjct: 215 MSQGRKFLQQAYETTKKKPIVLLKSGRSATGKRSAGSHTGSLAGMSEVANAAYGRAGITV 274

Query: 321 RRN--AIAPVSS 330
             N   + PV+ 
Sbjct: 275 IENSDELFPVAQ 286


>UniRef50_Q8PZY1 Acetyl-CoA synthetase, alpha subunit n=4 Tax=Archaea
           RepID=Q8PZY1_METMA
          Length = 468

 Score = 60.8 bits (146), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 48/286 (16%), Positives = 103/286 (36%), Gaps = 50/286 (17%)

Query: 38  GTPANKALLDTTGFWHDDFN--NATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQG 95
           GT  N        F  +      A+PN              ++  I++ L E   +    
Sbjct: 12  GTENNLDFF----FKPESIALIGASPN-----------PEKLSHTILKSLREMNFKGKIY 56

Query: 96  SG--SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFS----- 148
                 + +  ++ + +  +     ++A+ ++      +   +        ++ S     
Sbjct: 57  PVNPGYEEIEGLKCYSAPGEINNRIDIAIFAIPARAVLDTLKEPAGNIKGAVIVSSGFRE 116

Query: 149 ---DNVTLEDEIQLKTRAREKGLLVMGPDCGTS--MIAGTPLAFANV------MPEGNIG 197
                + +EDE++     +EKG+  MGP+C      ++     F         + +G + 
Sbjct: 117 MGPGGMKMEDELR--DLLKEKGIRAMGPNCLGIYDTVSNVDTFFIEREKIERPVRDG-VS 173

Query: 198 VIGASGTGIQELCSQIALAGEGITHAIGLGGR-DLSREVGGISALTALEMLSADEKSEVL 256
           V+  SG+    +  ++A  G G+   +  G + D++           LE L+ DE ++ +
Sbjct: 174 VLTQSGSFAAMIMDELANEGAGVARVVSYGNKVDVNES-------DCLEFLAEDEATKAV 226

Query: 257 AFVSKPPAEAVRLKIVNAMKAT--GKPTVALFLGYTPAVARDENVW 300
           A   +  + +   K + A       KP VAL +G     AR  +  
Sbjct: 227 ALYIE--SVSDGRKFLKAASGCVKKKPVVALKVGKREPGARAASSH 270


>UniRef50_UPI0001C165DF GCN5-related N-acetyltransferase n=2 Tax=Nostocaceae
           RepID=UPI0001C165DF
          Length = 993

 Score = 60.5 bits (145), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 43/324 (13%), Positives = 109/324 (33%), Gaps = 26/324 (8%)

Query: 18  MIISRKLSESEN-VDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAG 76
           M +++   + +  V + S+ +       +L T        +          I +      
Sbjct: 58  MALNKISQKLKGAVMEASIPLRLDKASDILRTE--KTSALDRIFAPQTVAVIGASEKPGS 115

Query: 77  IAQAIMQQLEEALKQLAQGSGSSQALT--QVRRWDSACQKLPDANLALISVAGEYAAELA 134
           + + ++  L            +    +   ++ + +        +LA+I+       ++ 
Sbjct: 116 VGRTLLWNLITNPFNGTVFPINPHRHSVLGIKAYPTIFDISEKIDLAVIATPAPTVPKII 175

Query: 135 NQALDRNLN-VMMFSDNVT------LEDEIQLKTRAREKGLLVMGPDCGTSM--IAGTPL 185
              +   +   ++ S          +  E ++ + A+   + ++GP+C   M  I+G   
Sbjct: 176 ADCVQVGIKGAIIISAGFKEAGEKGIALEKEILSVAQGGKIRIIGPNCLGMMNPISGLNA 235

Query: 186 AFAN-VMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTAL 244
            FA+ +   G++G +  SG     +         G +  + LG       +  IS    +
Sbjct: 236 TFASKIAQPGSVGFLSQSGALCTSILDWSLQENVGFSAFVSLG------SMLDISWGDLI 289

Query: 245 EMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT-----PAVARDENV 299
             L  D  ++ +    +    A             KP + +  G T      A +   ++
Sbjct: 290 YYLGDDPHTKSIVIYMESIGNARSFLSAAREVTLTKPIIVIKAGRTAAAAKAAASHTGSL 349

Query: 300 WFASSLDEAARLACLLSRVTARRN 323
             + ++ +AA   C + RV +  +
Sbjct: 350 AGSDAVLDAAFKRCGVLRVNSISD 373


>UniRef50_A8ZZJ4 CoA-binding domain protein n=2 Tax=Desulfobacteraceae
           RepID=A8ZZJ4_DESOH
          Length = 711

 Score = 60.5 bits (145), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 34/163 (20%), Positives = 69/163 (42%), Gaps = 23/163 (14%)

Query: 111 ACQKLPDA-NLALISVAGEYAAELANQALDRNLN-VMMFS--------DNVTLEDEIQLK 160
           +  ++PDA +LA+I +  +      +  +++ +  V++ S        +   +E+ +   
Sbjct: 60  SLLEVPDAVDLAMIILPPKATLAAIHDCIEKKVKGVVIVSAGFREVGGEGKQIEESVA-- 117

Query: 161 TRAREKGLLVMGPDCGTSMIAGTPL----AFANVMP-EGNIGVIGASGTGIQELCSQIAL 215
              R+ G+ V+GP+C   +   + +    +F+  MP +GNI  I  SG     +    + 
Sbjct: 118 ALCRKAGIRVVGPNCLGVINPNSKVRLNASFSRRMPSQGNISFISQSGALCTAVLDFASD 177

Query: 216 AGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAF 258
            G G +  I  G +    E      L  L  L  D  ++V+  
Sbjct: 178 MGVGFSKFISTGNKADVDE------LDLLTYLHKDPATDVIMM 214


>UniRef50_Q47QC0 Putative uncharacterized protein n=2 Tax=Nocardiopsaceae
           RepID=Q47QC0_THEFY
          Length = 886

 Score = 60.5 bits (145), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 35/204 (17%), Positives = 75/204 (36%), Gaps = 16/204 (7%)

Query: 112 CQKLPDANLALISVAGEYAAELANQALDRNL-NVMMFSDNVTLEDEIQLKTRAREKGLLV 170
             ++PD  LA++SV  +   ++A    ++ +  +++ + ++  E   +L    R  G+ +
Sbjct: 252 LPEVPD--LAVVSVPPDAVLDVARACGEQGVGALVVITADLDTETSQELLAVCRWHGMRL 309

Query: 171 MGPDCGTSMIAGTPLAF-----ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIG 225
           +GP+C         +       A     G  G++  SG     L   ++    GI+  + 
Sbjct: 310 VGPNCFGVASLSDGVRLQATFAAEAPRPGQAGLVVQSGGIGITLLEHLSRLDVGISSFVS 369

Query: 226 LGGR-DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
            G + D+S           L+    D  + +     +      +   +       KP + 
Sbjct: 370 TGNKLDVSSN-------DLLQWWEDDPDTAMAIMHVESFGNPRKFSRIARRLGRRKPILT 422

Query: 285 LFLGYTPAVARDENVWFASSLDEA 308
           +  G + A  R       +SL  A
Sbjct: 423 VVAGRSTAGQRAAASHTGASLTPA 446


>UniRef50_A4WJJ0 CoA-binding domain protein n=3 Tax=Pyrobaculum RepID=A4WJJ0_PYRAR
          Length = 484

 Score = 60.5 bits (145), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 52/251 (20%), Positives = 96/251 (38%), Gaps = 27/251 (10%)

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQL----AQGSGSSQALTQVRRWDSACQKLP 116
           PN + V   S  AD+   Q ++Q L+    ++     +         +V+ ++SA   LP
Sbjct: 7   PNSVAVVGASPKADSIGGQILLQLLKSFKSRVYAVNPKYRRGEVGGVEVQFYESA-TNLP 65

Query: 117 DAN-LALISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLV 170
           +A  L +++   E    + + A        +     FS+    + E +L   A++ G+ V
Sbjct: 66  EAPELVVVATPAEITPRVVDDAGRAGAKAAIVVSGGFSEIGRRDLENELVKTAQKHGMRV 125

Query: 171 MGPDCGTS--MIAGT-----PLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHA 223
           +GP+C        G      P+  A   P G I  +  SG  +       A  G G+  A
Sbjct: 126 LGPNCIGVYNAFNGLDTMFLPVEKAARPPPGPIAFLSQSGAVMTAALDWAAGEGIGVGIA 185

Query: 224 IGLGGR-DLSREVGGISALTALEMLSADEKSEVLAFVSKP-PAEAVRLKIVNAMKATGKP 281
           +  G R D++           +E L+  ++  V+A   +    +    + +   K + KP
Sbjct: 186 VNFGNRADVTEA-------DFIEFLANSKEISVIALYLEGFRWKGDAARFLKVAKRSSKP 238

Query: 282 TVALFLGYTPA 292
            V    G    
Sbjct: 239 VVVYKAGRGSD 249


>UniRef50_UPI0000510214 CoA-binding domain protein n=1 Tax=Brevibacterium linens BL2
           RepID=UPI0000510214
          Length = 890

 Score = 60.1 bits (144), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 39/210 (18%), Positives = 77/210 (36%), Gaps = 21/210 (10%)

Query: 110 SACQKLPD-ANLALISVAGEYAAELANQALDRNLN-VMMFSDNVT------LEDEIQLKT 161
              + LP  A+LA+I+V  E A E+  +     +  V++ S           E + ++  
Sbjct: 246 RTLEDLPGTADLAVIAVPAESATEVVQECAAHGVKAVLVISSGFAETGDEGAELQRRMVA 305

Query: 162 RAREKGLLVMGPDCGTSMIAGTPLAFANVMPE-----GNIGVIGASGTGIQELCSQIALA 216
            +R  G+ V+GP+    +     ++    +       G++G+   SG     L S     
Sbjct: 306 TSRAYGMRVVGPNSFGLVNEAADVSLNASLAPFLPDSGSLGLFSQSGALGTALLSAAKNR 365

Query: 217 GEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVL-AFVSKPPAEAVRLKIVNAM 275
           G GI+  +  G R        +S    L+    D  ++ +  ++          +I   +
Sbjct: 366 GLGISTFVSAGNR------ADMSGNDVLQYWEEDPDTKTVGLYLESIGNPRKFSRIARRV 419

Query: 276 KATGKPTVALFLGYTPAVARDENVWFASSL 305
               KP + +    T       ++   SSL
Sbjct: 420 SRV-KPIIVIKSDLTGRELPPGHIVRTSSL 448


>UniRef50_Q2LS75 Acetyl-CoA synthetase beta subunit n=1 Tax=Syntrophus
           aciditrophicus SB RepID=Q2LS75_SYNAS
          Length = 697

 Score = 60.1 bits (144), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 71/399 (17%), Positives = 128/399 (32%), Gaps = 57/399 (14%)

Query: 104 QVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLED------E 156
            +R + S  +     NL +IS+  +       + +   +  VM+ S      D      +
Sbjct: 51  GLRAFPSITEVPETVNLVIISMGRDQVVAAFKECIQSGVKRVMIVSQGFADADPHGEKLQ 110

Query: 157 IQLKTRAREKGLLVMGPDCGTSM--IAGTPLAFANVMPEG---NIGVIGASGTGIQELCS 211
            ++   ARE G+ V+GP+    +        +F +++       + +I  +G  IQ    
Sbjct: 111 NEIVRLARESGIRVVGPNTLGILNNFRNFSTSFVDLIKPKKIPPVSLIAQTG-MIQVASH 169

Query: 212 QIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKI 271
            +A    G    IG            +  + ALE   AD ++ V+    +          
Sbjct: 170 NLAYHDWGKALDIGNACD--------VDFVDALEYFGADPETRVIVVHMEGIIRGREFLK 221

Query: 272 VNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSG 331
             +  +  KP +    G T A A+      AS   E        +R    R         
Sbjct: 222 AASRISPDKPIIIFKTGRTTAGAKAALSHTASLTGEDEIAEAAFNRAGLIRVKNGSELKD 281

Query: 332 FIC-------------GLYT----GGTLAAEA----AGLLAGHLGVEADDTHQHGMMLDA 370
            I              G+ T    GG +A +A       +A       D   +       
Sbjct: 282 AIRSFIQFEDMEGPRLGVLTPTGAGGIMATDACEDFGLKIAELPEGLPDKLKKGIPDWVH 341

Query: 371 DSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATAD-PAA 429
             + I     D + VG          R   + +L   P+V     D V+G   + D P  
Sbjct: 342 IGNPI-----DIWPVGMLGGGYSQAYR-TALMELLKSPKV-----DGVLGVTVSVDSPLH 390

Query: 430 SLVSAWQKACAARLDN---QPLYAIATVTGTERDPQCRS 465
             +   +   AAR ++   +P+      +GT+   +   
Sbjct: 391 KNIDIVEAVAAARRESGSRKPIAMWVYGSGTDDTVERLE 429


>UniRef50_C5U6W7 CoA-binding domain protein n=1 Tax=Methanocaldococcus infernus ME
           RepID=C5U6W7_9EURY
          Length = 667

 Score = 60.1 bits (144), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 51/252 (20%), Positives = 101/252 (40%), Gaps = 18/252 (7%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
           +AI       G A  +I++ L +   +L   +     +  ++ + S        +LA+I 
Sbjct: 7   IAIIGATPKEGKAGYSILKNLLKFKGKLYPINPKYSEIFGIKCYKSILDVDDKIDLAIIV 66

Query: 125 VAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSM 179
           V      ++  +   + +  ++     FS+   +E E +++   ++  +  +GP+C   +
Sbjct: 67  VPNVVVPQVLEECGKKGVKYVVIISAGFSEVGNVELENKVRGILKKYNIRAIGPNCFGLI 126

Query: 180 IAGTPL--AFANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR-DLSREV 235
            A   L   F+ V P +GNI +I  SG  I  +   + L   G++  + LG + D+    
Sbjct: 127 NAHINLNATFSKVFPEKGNISLISQSGAVIDAILDILPLLNIGVSKVVSLGNKIDIQES- 185

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVAR 295
                   LE+L  DE++ V+  +     +      V    A  KP + L  G + A  R
Sbjct: 186 ------DILEILKDDEETRVI-GIYLESLKDKNFLKVAKEVAKKKPIIVLKAGKSEAGKR 238

Query: 296 DENVWFASSLDE 307
                  +   E
Sbjct: 239 AAKSHTGALAGE 250


>UniRef50_B9Z1Z5 GCN5-related N-acetyltransferase n=1 Tax=Lutiella nitroferrum 2002
           RepID=B9Z1Z5_9NEIS
          Length = 893

 Score = 60.1 bits (144), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 49/237 (20%), Positives = 86/237 (36%), Gaps = 22/237 (9%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMM----FSDNVTL 153
           + + +  +R   S      +  LA+++ A      +      + +  ++    F+D+  L
Sbjct: 50  NHKVVGGMRAVPSVRLIEGEVELAVVTTALRALPAILRDCGKKGVKAVLLAKEFADSEQL 109

Query: 154 EDEIQLKT---RAREKGLLVMGPDCGTSMIAGTPLAFAN---VMPEGNIGVIGASGTGIQ 207
           E EI LK     AR  G+ V+GP+    M        +N    +  GN+ ++  S     
Sbjct: 110 EREI-LKESLSIARHFGIRVLGPNVLGLMRPVAGFNASNYSSKVRPGNLALVSQSSALCT 168

Query: 208 ELCSQIALAGEGITHAIGLG-GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEA 266
            +       G G +  I +G G D+            L+ L AD  ++ +        +A
Sbjct: 169 AMLDWADSKGIGFSSVISVGEGLDV-------DFGEILDYLVADTFTQGILLHVHHIHDA 221

Query: 267 VRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAAR-LACLLSRVTARR 322
            R        A  KP V +  G          +  +S+L E+A      LSR    R
Sbjct: 222 RRFISALRAAARTKPVVVIKSGRYEDDVT--GLTHSSNLVESADVFDAALSRAGVLR 276


>UniRef50_C0D886 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0D886_9CLOT
          Length = 695

 Score = 60.1 bits (144), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 77/484 (15%), Positives = 145/484 (29%), Gaps = 100/484 (20%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLALI 123
           + +   +  +G      + + E +++ +    +     +     + +  +     +LA+I
Sbjct: 12  ICVIGASEKSGFGGDTCRNVIEYMREGSYYFVNPGRDEVFGKPCYRTVEEVPGSFDLAVI 71

Query: 124 SVAGEYAAELANQ---ALDRNLNVMMFSDNVTL------EDEIQLKTRAREKGLLVMGPD 174
               +   E   +   A      V+  S    +      E++ +L    +E  + +MGP+
Sbjct: 72  CTP-QGTVEELLKSSRAKGAGAAVVFASGYKEIGSAQGRENQERLTRLCKELDMALMGPN 130

Query: 175 CGTSMI---AGTPLAFANVM--PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
           C   +       P AF +     +G +GV+  SG   Q   S +   G   ++ I  G  
Sbjct: 131 CAGFVNYTDDVYPFAFLSESRDRKGTVGVVSQSG---QICLSLMDSPGMKFSYVISSGNS 187

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRL-KIVNAMKATGKPTVALFLG 288
            +      +     LE L  DE ++V+A   +      +    +       KP V L  G
Sbjct: 188 AV------VRMEDYLEFLVEDESTKVVAMYLEGVQNVPQFLDCLKRAAMKRKPVVILKAG 241

Query: 289 YTP---------------------AVARDENVWFASSLDEAARLACLLSRVTARRNAIAP 327
            +                      AV R   V     ++E   ++ + S +         
Sbjct: 242 RSEKGGRLAASHTGSLSGADAVFDAVFRKYGVIRVDDVEELMAVSMMFSILPGLPKRPGI 301

Query: 328 VSSGFICGLYTGGT----------------LAAEAAGLLAGHLGVEADDTHQHGMMLDAD 371
            S      L  G T                  AE    L   L            M    
Sbjct: 302 ASMN----LSGGETGVCADVGQTWGIEYPDFQAETLERLREQL-PSYASPANPLDMTATL 356

Query: 372 SHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATA---DPA 428
           S+                   D       +  + + P V ++     IG+       DPA
Sbjct: 357 SY-------------------DVQAYAGALRTVMSDPNVGLVA----IGYTLLERIADPA 393

Query: 429 ASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLL 488
              ++   +  AA    +P+  I  +  T        +    LE AG+ V+     A  +
Sbjct: 394 ICYMTEAIELVAAEPGAKPMVMIPFLENTRN-----EEYARRLECAGVPVLPPTVYAFKI 448

Query: 489 AAAL 492
              L
Sbjct: 449 LRYL 452


>UniRef50_A8BPG2 Acetyl-CoA synthetase n=4 Tax=Hexamitidae RepID=A8BPG2_GIALA
          Length = 726

 Score = 60.1 bits (144), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 29/200 (14%), Positives = 76/200 (38%), Gaps = 24/200 (12%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVT---- 152
           ++  +   + + S        ++ ++ +  +     A +   + +  +++ +        
Sbjct: 59  TATEILGYKTYKSVLDVPDSIDVVIVVIPSKAVLAAAKECAQKKVKSLVVITAGFKEIGG 118

Query: 153 --LEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMP-EGNIGVIGASGTGIQEL 209
             ++ E  L    ++ G+ ++GP+C   +       FA+  P +G+I  +  SG     L
Sbjct: 119 EGVQMEQDLTKICKDAGIRLVGPNCLGIVTPNLNCTFASAKPSKGSIAFLSQSGAM---L 175

Query: 210 CSQIALA---GEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEA 266
            S +  A   G G ++ I LG +    EV        +  ++ D  ++++    +   + 
Sbjct: 176 TSILDWALTNGIGFSNFISLGNKADVDEV------DLIMEVAEDPNTDIILLYLESIVD- 228

Query: 267 VRLKIVNAMKAT--GKPTVA 284
              K +  +      KP + 
Sbjct: 229 -GRKFLEQIPTCVHKKPVII 247


>UniRef50_C0GIF8 CoA-binding domain protein n=1 Tax=Dethiobacter alkaliphilus AHT 1
           RepID=C0GIF8_9FIRM
          Length = 716

 Score = 59.7 bits (143), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 35/137 (25%), Positives = 57/137 (41%), Gaps = 11/137 (8%)

Query: 155 DEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMP----EGNIGVIGASGTGIQELC 210
            E +L+  AR   +  +GP+C   M +   L    VMP     G +G+   SGT + +  
Sbjct: 114 KEEELQEIARRHNIRFLGPNCIGMMNSQISLN-TTVMPLSGQPGRLGMASQSGTYVTQTF 172

Query: 211 SQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK 270
           S +   G   + AI +G          I    ALE L  DE+++ +A   +   +  R  
Sbjct: 173 SYLKERGIHFSKAISVGNE------TDIDITDALEYLGQDEETKAIALYIEGIKDGARFI 226

Query: 271 IVNAMKATGKPTVALFL 287
            V       KP +A ++
Sbjct: 227 DVAQKITPHKPVIAQYV 243


>UniRef50_A8MDR5 CoA-binding domain protein n=7 Tax=Thermoprotei RepID=A8MDR5_CALMQ
          Length = 477

 Score = 59.7 bits (143), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 43/230 (18%), Positives = 85/230 (36%), Gaps = 29/230 (12%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVT---- 152
              ++   + + S  +   + +LA+I+V      ++  +A+ +N+  +++ S   +    
Sbjct: 58  RYDSINGAKCYKSITEVNDEVDLAVIAVPAPVVPQVTAEAVKKNVKALIIISGGFSEVGD 117

Query: 153 ----LEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPL-------AFANVMPEGNIGVIGA 201
               LEDE++     +   + V+GP+C     A   L             P+G I +I  
Sbjct: 118 EGRRLEDEVR--EIVKNTQVRVLGPNCIGVYNADNGLDTFFLPEDRMGRPPKGPIALISQ 175

Query: 202 SGTGIQELCSQIALAGEGITHAIGLGGR-DLSREVGGISALTALEMLSADEKSEVLAFVS 260
           SG     +    +    GI  A+  G + D++           LE L+ +   +V+    
Sbjct: 176 SGAVAAAILDWASRRRLGIGLAVNYGNKLDVNES-------ELLEYLANNSNVKVITIYM 228

Query: 261 KP---PAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDE 307
           +    P E +R           KP +    G T A A       A+   +
Sbjct: 229 EGLKYPGEGLRFLETAKKVTQIKPVIVYKAGRTKASAGAVASHTAALAGD 278


>UniRef50_D1C154 CoA-binding domain protein n=1 Tax=Sphaerobacter thermophilus DSM
           20745 RepID=D1C154_SPHTD
          Length = 743

 Score = 59.7 bits (143), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 47/251 (18%), Positives = 85/251 (33%), Gaps = 22/251 (8%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSA-CQKLPDA-NLALI 123
           +AI   +   G A  I ++L +   +      +      +        + +P   +LA++
Sbjct: 34  IAIVGASPKRGFANNIQRRLVDCGFEGEVYPVNPNYDEILGLPCYPSLEAIPGGVDLAVV 93

Query: 124 SVAGEYAAELANQALDRNLNVMMF---------SDNVTLEDEIQLKTRAREKGLLVMGPD 174
            V       +        +  +            D    E +  ++  AR  G+ V+GP+
Sbjct: 94  VVPSRLIPGVLESCERAGVGAVNIITSGFAEKQEDETGPERQRAIRDFARRTGIRVVGPN 153

Query: 175 C-GTSMIAGTPLAFANVMPE---GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
           C G   +    +A +   P    G I +   SG     L       G G T+ + LG   
Sbjct: 154 CLGNISVPNRMVASSGAYPPLNRGPIALALQSGLLAYSLVLPAHDRGIGFTYVVTLGNE- 212

Query: 231 LSREVGGISALTALEMLSADEKSEVL-AFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
                  I  +  +     DE++ V+  FV +       L++       GKP V L +G 
Sbjct: 213 -----ADIDVVDMIRYYLDDEETRVIGCFVEQFRRLERLLEMAERAADLGKPIVVLKVGR 267

Query: 290 TPAVARDENVW 300
           + A  R     
Sbjct: 268 SEAGRRAALAH 278


>UniRef50_C6E214 CoA-binding domain protein n=3 Tax=Geobacter RepID=C6E214_GEOSM
          Length = 697

 Score = 59.7 bits (143), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 37/206 (17%), Positives = 72/206 (34%), Gaps = 23/206 (11%)

Query: 110 SACQKLPD-ANLALISVAGEYAAELANQALDRNLNVMMFS---------DNVTLEDEIQL 159
               ++PD  +LA + +  ++  +   +   + +  ++ +         +   L+D+   
Sbjct: 59  KTLDEIPDQIDLAHVIIPSQFVPQTIEECGKKGIKAVIINSAGFCELGEEGAQLQDD--F 116

Query: 160 KTRAREKGLLVMGPDCGTSMIAGTPL-AFANVM----PEGNIGVIGASGTGIQELCSQIA 214
             R  E G+ V GP+C   + +   L A+ N        G++ V+  SG     +   +A
Sbjct: 117 LRRGEEFGVRVFGPNCQGIINSDPALKAYCNFTFTFPEPGHVSVVALSGGVGALIMQALA 176

Query: 215 LAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNA 274
             G G       G          IS    L     DE +  +   ++          V  
Sbjct: 177 DLGVGQRFYASNG------NACDISVTEILSYYGEDEGTRAVVLYTEGFPNPGEFLAVAR 230

Query: 275 MKATGKPTVALFLGYTPAVARDENVW 300
             A  KP +A+  G T   A+  +  
Sbjct: 231 EVAAKKPILAMKAGRTEQGAKAASSH 256


>UniRef50_D0LBS1 CoA-binding domain protein n=2 Tax=Corynebacterineae
           RepID=D0LBS1_GORB4
          Length = 950

 Score = 59.7 bits (143), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 55/298 (18%), Positives = 101/298 (33%), Gaps = 25/298 (8%)

Query: 48  TTGFWHDDFNNATPN---DICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQ 104
             GF    F    P    D    +  + AD G A+          +    G  + +    
Sbjct: 243 AGGFTGPVFPVNGPGHGPDDAADVGDDPADHGTARPSAAGGASGSRGSVAGRRTRERPPS 302

Query: 105 VRRWDS--ACQKLPD-ANLALISVAGEYAAELANQALDRNLNVMMF-------SDNVTLE 154
           VR   +    + +PD  +LA+++V  E   ++ +  L + +  ++        S    L 
Sbjct: 303 VRGIRAYETVRDIPDPVDLAVVAVPAERVPDVLDDCLVKAVRTLVVVSSGFADSGAQGLA 362

Query: 155 DEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAF-ANVMPE----GNIGVIGASGTGIQEL 209
            E +L  + RE G+ ++GP+          +A  A + P     G +G    SG     +
Sbjct: 363 SEHRLVEQVREHGMRLVGPNALGVANNDPTVALNATLAPRIPAVGRVGFFCQSGALGIAI 422

Query: 210 CSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRL 269
               A    G++  +  G R    +V G   L        D  ++V+    +      + 
Sbjct: 423 LDTAARRQIGLSTFVSAGNR---ADVSGNDLLQ---YWDTDTATDVVLLYLESFGNPRKF 476

Query: 270 KIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEA-ARLACLLSRVTARRNAIA 326
             +    +  KP VA+  G             A+ LD+  AR+    + V        
Sbjct: 477 SRIARRVSRSKPIVAVKSGKGALTPVRAARSGAAGLDDQIARMVLEQAGVIQVDTIPE 534


>UniRef50_Q0K2Q5 6-Carboxyhexanoate-CoA ligase n=2 Tax=Cupriavidus
           RepID=Q0K2Q5_RALEH
          Length = 716

 Score = 59.7 bits (143), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 47/238 (19%), Positives = 91/238 (38%), Gaps = 29/238 (12%)

Query: 94  QGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMF------ 147
             +   Q L  V   D        A+LA++++    + +   Q         +F      
Sbjct: 47  ATAREVQGLAAVPSLD---ALDTPADLAIVALPVSASLDTMRQLARNGTRAAVFFTSGFA 103

Query: 148 ---SDNVTLEDEIQLKTRAREKGLLVMGPDCGTSM-------IAGTPLAFANVMPEGNIG 197
               D + ++ E+    +A   G+ ++GP+C  +M          +P+  + + P G +G
Sbjct: 104 ETGGDGIAMQAELAALAQAH--GITLLGPNCLGAMNLRERVFATFSPMPLSGLPPLGEVG 161

Query: 198 VIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLA 257
           ++  SG            A  G++H +  G         G+     +E L+ D+ + V+ 
Sbjct: 162 LVSQSGAFGAYAFGLAREASLGLSHWVTTGNE------AGLHVADVIEWLAHDDATRVIL 215

Query: 258 FVSKPPAE-AVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFAS-SLDEAARLAC 313
              +   +     + + A +A GKP V   +G T A AR      AS + ++A   A 
Sbjct: 216 AYLEGCRDGTRLRRALAAARAAGKPVVVTKVGTTEAGARSAQSHTASLAGEDAVYQAV 273


>UniRef50_B4RED1 Acetyl-CoA synthetase / acetyltransferase (GNAT) family protein n=2
           Tax=Alphaproteobacteria RepID=B4RED1_PHEZH
          Length = 889

 Score = 59.3 bits (142), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 42/235 (17%), Positives = 78/235 (33%), Gaps = 25/235 (10%)

Query: 66  VAIRSEAADAGIAQAIMQ---QLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   +   G    ++    +       L   +   + +     + S        +LA+
Sbjct: 15  IALIGASDRPGSVGDVVARNLKAGGFPGPLMFVNPKGKTILGETAFRSVADLPHAPDLAV 74

Query: 123 ISVAGEYAAELANQALDRNLNV-MMFSDNVTLEDEI------QLKTRAREKGLLVMGPDC 175
           I+        L +    R     ++ S     +DE        L   AR   L ++GP+C
Sbjct: 75  IATPAPTLPGLVSDLGARGCRAAVVISAGFEAQDEATARLRQALLDAARPHLLRIVGPNC 134

Query: 176 GTSMIA--GTPLAFA-NVMPEGNIGVIGASGTGIQELCSQIALA---GEGITHAIGLGGR 229
              M    G   +FA    P G + ++  SG       + +  A   G G +H + LG  
Sbjct: 135 LGFMSPRRGINASFARGSAPPGGVALVAQSGAVA---SALLDWAPAHGVGFSHVVTLG-- 189

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
                   +     L+ L  D +++ +    +   EA +        A  KP V 
Sbjct: 190 ----NALDVDVADMLDHLGRDPETKAILLYLEGLREARKFMSAARFAARSKPVVV 240


>UniRef50_C5CCL1 Acyl-CoA synthetase (NDP forming) n=8 Tax=Bacteria
           RepID=C5CCL1_MICLC
          Length = 909

 Score = 59.3 bits (142), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 35/220 (15%), Positives = 75/220 (34%), Gaps = 24/220 (10%)

Query: 77  IAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQ 136
           + +A       A+ + A+      A   +             +L +++V  +    L  +
Sbjct: 227 VLEAGFTGAVHAVNRAAEDVQGLTAHRSLADIGEPV------DLVVVAVPADEVEALIPE 280

Query: 137 ALDRNLN-VMMFSDNVT------LEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAF-- 187
           A       +++ +          LE + +L + AR  G+ V+GP     +     +    
Sbjct: 281 AAAAGAQGLVVLTSGYADAGAEGLEAQRRLVSLARAHGMRVIGPASAGLVRTDPAIRLNA 340

Query: 188 ---ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTAL 244
                +   G +G+   SG     + + +   G GI+ +I  G R    +V G     A+
Sbjct: 341 SPSPGLAQRGPVGLFSQSGAVGAMVSAGVKRRGVGISTSISAGNR---ADVSGN---DAM 394

Query: 245 EMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
           +   AD  +  +    +      +   +    +  KP V 
Sbjct: 395 QFFEADPHTAAVGVYLESFGNPRKFSRIARRLSRTKPVVV 434


>UniRef50_B8FCT2 CoA-binding domain protein n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FCT2_DESAA
          Length = 464

 Score = 59.3 bits (142), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 65/445 (14%), Positives = 136/445 (30%), Gaps = 63/445 (14%)

Query: 88  ALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMM 146
           AL  +         +      D   + +   +L +  +   +A +    A       V  
Sbjct: 40  ALYPVNPAHAEISGVKAYPSLDDVPETV---DLVIAQIPARFAIDTVKAAGRNGAPFVHF 96

Query: 147 FSDNVT----LEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPE---GNIGVI 199
           F+   +    +E E +L   AR   + ++GP+C   + A + + F         GN+G +
Sbjct: 97  FTSGFSEVGNMELEKELVETARASNVRLVGPNCIGVLCAESRITFNMEFKPNGKGNVGFL 156

Query: 200 GASGTGIQELCSQIALAGEGITHAIGLGGR-DLSREVGGISALTALEMLSADEKSEVLAF 258
           G SG                +  A+  G + DL  E         L   + D + E  A 
Sbjct: 157 GQSGGVSDNFVRMSGSRKIRLNKAVSYGNQADLKLE-------DFLAYFAEDPEIEAAAI 209

Query: 259 VSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSR- 317
             +                  KP + L  G T   A+       +   +    +  +++ 
Sbjct: 210 YVEDVKNGPAFLDALGKTTASKPVILLKGGSTQRGAKAAASHTGAMAGDFKIFSSAVNQK 269

Query: 318 --------VTARRNAIAPVSSGFICG-----LYTGG-------TLAAEAAGLLAGHLGVE 357
                          +   S+    G     L  GG        LAA+A   +       
Sbjct: 270 GGIIVDTFEQMMDLMMLATSTRLPRGNRVGFLGAGGGTSVCFTDLAAKAGLEMPVLAQAV 329

Query: 358 ADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLL--- 414
            D   +    ++  +   +DLG   +         D ++    +  +     + V++   
Sbjct: 330 QDRISEKIPNVNTSTANPVDLGAFGF---------DFSIMAHTMLAMDQDENIDVIMPYF 380

Query: 415 -LDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQI----A 469
            LD +  F       AS          A++    +  ++       D     +      +
Sbjct: 381 SLDFITSFAPH---MASSGPEIILETVAKMKKPVIPILSKF---AEDVLEMEKVRIEMFS 434

Query: 470 TLEDAGIAVVSSLPEATLLAAALIH 494
              + G+AV +++ +    A++++ 
Sbjct: 435 VFREGGLAVFNTIQDCVNAASSILK 459


>UniRef50_Q30WE4 Acetyltransferase, GNAT family n=4 Tax=Desulfovibrio
           RepID=Q30WE4_DESDG
          Length = 911

 Score = 58.9 bits (141), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 27/145 (18%), Positives = 50/145 (34%), Gaps = 9/145 (6%)

Query: 159 LKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMP---EGNIGVIGASGTGIQELCSQIAL 215
           +   A+  G+ ++GP+C   +     +  +        G I  +  S +    +      
Sbjct: 119 VMDIAQAHGMRILGPNCLGFINPSVGVNASLAHREALPGRIAFVSQSDSLFTSVLDWATS 178

Query: 216 AGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAM 275
            G G +H I LG R        I+    L+ L+ D  +  +    +  + A R       
Sbjct: 179 KGVGFSHFISLGDR------YDINFADILDYLNNDPGTRAVLLYLETISGARRFMSAARA 232

Query: 276 KATGKPTVALFLGYTPAVARDENVW 300
            A  KP + +  G + A A      
Sbjct: 233 LARNKPVLVMKSGKSEASATAAAAH 257


>UniRef50_B8FIP4 CoA-binding domain protein n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FIP4_DESAA
          Length = 695

 Score = 58.9 bits (141), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 41/207 (19%), Positives = 73/207 (35%), Gaps = 21/207 (10%)

Query: 112 CQKLPDANLALISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTR--AR 164
              +PD   +LI    +   ++  +     +  M      FS+     D++  +T   AR
Sbjct: 63  LPIIPDIVYSLI--PAKLVPDMVERCGKMGVKRMAIPSGGFSEFGGRGDDLAQQTLDAAR 120

Query: 165 EKGLLVMGPDCGTS--MIAGTPLAFANVMPE--GNIGVIGASGTGIQELCSQIALAGEGI 220
           + G+  +GP+  T   +  G  L FA V+    GNI V+  SG     + +       G+
Sbjct: 121 KYGIRFVGPNGLTLANVKNGLCLPFAPVVKPPLGNISVVSQSGGVGLMIMTHFKAENLGM 180

Query: 221 THAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGK 280
                +G +    EV        LE    D  +E++    +  +     ++        K
Sbjct: 181 AKFASIGNKLDLDEV------DFLEYFGQDPDTEIIFMYLE--SIIRGRELAEMASRINK 232

Query: 281 PTVALFLGYTPAVARDENVWFASSLDE 307
           P V      T +  R      AS   +
Sbjct: 233 PVVVFKSNTTDSGKRAAMSHTASVSSD 259


>UniRef50_Q7VRY7 Acetyl-CoA synthetase n=3 Tax=Bordetella RepID=Q7VRY7_BORPE
          Length = 729

 Score = 58.9 bits (141), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 50/276 (18%), Positives = 98/276 (35%), Gaps = 55/276 (19%)

Query: 119 NLALISVAGEYAAELANQALDRNLNVMMF---------SDNVTLEDEIQLKTRAREKGLL 169
           +LA+++V   +     +  +       +          ++ V ++ E  L  RAR  G+ 
Sbjct: 81  DLAIVAVPAAHVLATFDDVVAAGARAAIVYTSGFAEIGAEGVKVQAE--LTARARASGVR 138

Query: 170 VMGPDCGTSMIAGTPLA--FANVM-----PEGNIGVIGASGTGIQELCSQIALAGEGITH 222
           V+GP+C   +   + L   F+  +       G+IG+   SG             G   + 
Sbjct: 139 VLGPNCLGVINTRSKLIATFSGAVGHAPPRPGSIGLASQSGALGAHCLVLAERRGIAFS- 197

Query: 223 AIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVR-LKIVNAMKATGKP 281
                G +   +V        +  ++ D  + V+    +   +A R ++ +   +  GK 
Sbjct: 198 VWATSGNESDIDV-----AELIAYMATDPGTHVIVACIEGVRDAGRLIEALELARTHGKQ 252

Query: 282 TVALFLGYTP---------------------AVARDENVWFASSLDEAARLACLLSRVTA 320
            V + +G +P                     AV R+  V+ A S+++   +A  L+   +
Sbjct: 253 IVMMKVGSSPIGAAAAASHTASMVGSDQVFDAVLREFGVYRAHSIEDMLDVAYALTVHQS 312

Query: 321 RRNAIAPVSSGFICGLYTGGT---LAAEAAGLLAGH 353
            R     V +       +GG    LA EA  L    
Sbjct: 313 PRGRSLAVVTT------SGGVGVLLADEAERLGVDM 342


>UniRef50_D1ABG8 CoA-binding domain protein n=3 Tax=Streptosporangineae
           RepID=D1ABG8_THECD
          Length = 821

 Score = 58.9 bits (141), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 35/163 (21%), Positives = 59/163 (36%), Gaps = 11/163 (6%)

Query: 156 EIQLKTRAREKGLLVMGPDCGTSMIAGTPL----AFANVMP-EGNIGVIGASGTGIQELC 210
           + +L   AR  G+ V+GP+C         +    + A  MP  G IG    SG     + 
Sbjct: 303 QRELVRLARANGMRVVGPNCLGIANTDPAVRLNASLAPTMPGRGPIGFFSQSGALGIAIL 362

Query: 211 SQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK 270
            + A  G G++  +  G R    +V G   L        D  + V+    +      +  
Sbjct: 363 QRAAERGLGLSTFVSAGNR---ADVSGNDLLQ---YWEEDPATGVVLLYLESIGNPRKFT 416

Query: 271 IVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLAC 313
            +    +  KP VA+  G +       +   A +L + A  A 
Sbjct: 417 RLARRISRAKPIVAVKTGRSTQGVPLGHAARALTLPDHAVSAL 459


>UniRef50_Q72GY5 6-carboxyhexanoate-CoA ligase n=3 Tax=Thermus RepID=Q72GY5_THET2
          Length = 745

 Score = 58.5 bits (140), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 51/273 (18%), Positives = 99/273 (36%), Gaps = 21/273 (7%)

Query: 66  VAIRSEAADAGIA------QAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPD-A 118
           VA+   + D            I  + +  +  + +  G               + +P   
Sbjct: 208 VAVVGASRDPESIGYRVLENLIFGRFQGPVFPVNEAIGREGGTVGPLLAYPGLESVPGPV 267

Query: 119 NLALISVAGEYAAELANQALDRNLNV-MMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           +L +++V  E   E    A  R     ++ +   T ++   L  +AR  G+ ++GP    
Sbjct: 268 DLVVVAVPKERVPEALEAAGRRGARGAIVLTTGFTPKEAQALADKARRLGMRLLGPGSLG 327

Query: 178 SMIAGTPL----AFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
            +     +      A +  EG + +   SGT  + + +     G G+   + LG +    
Sbjct: 328 LVHTHPGVRLAAGLAPLPKEGVLAISSQSGTLGRAVLAFAEEMGLGVASFVSLGAK---- 383

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP-- 291
               IS+   L+    DE++ V+    +      R   +       KP +A+     P  
Sbjct: 384 --ADISSNDLLQFWEEDERTRVILLYLEHFGNPRRFSRLARRIGKKKPILAVHPSRDPLV 441

Query: 292 -AVARDENVWFASSLDEAARLACLLSRVTARRN 323
            A+     V  A+SL+EA  +A LL++     N
Sbjct: 442 RALFAQAGVVRANSLEEAFDVALLLAQGPLPEN 474


>UniRef50_UPI0001B582AA succinyl-CoA synthetase subunit alpha n=1 Tax=Streptomyces sp. C
           RepID=UPI0001B582AA
          Length = 226

 Score = 58.5 bits (140), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 16/93 (17%), Positives = 37/93 (39%), Gaps = 4/93 (4%)

Query: 90  KQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNV-MMFS 148
           K           +        A +K   AN++++ V   +A     +A+D  + + ++ +
Sbjct: 28  KAGTSVDFDGTEVPVFGSVAEAMEKTG-ANVSVLFVPPAFAKAAVVEAIDAEIPLAVVIT 86

Query: 149 DNVTLEDEIQLKTRAREKG--LLVMGPDCGTSM 179
           + + + D       A  KG    ++GP+C   +
Sbjct: 87  EGIAVHDSAAFWAYATAKGNKTRIIGPNCPGLI 119


>UniRef50_A0QZM0 CoA-binding protein n=3 Tax=Corynebacterineae RepID=A0QZM0_MYCS2
          Length = 687

 Score = 58.1 bits (139), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 38/229 (16%), Positives = 81/229 (35%), Gaps = 15/229 (6%)

Query: 96  SGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMM-----FSDN 150
           +    ++       S  +     +L  I+V           AL      ++     F++ 
Sbjct: 48  NRRGDSVLGQPPLRSLAEVDGAVDLVAITVPAHSFEAAVEDALAAGARAIVGVTAGFAEL 107

Query: 151 VTLEDEI--QLKTRAREKGLLVMGPDCGTSMIAGTPLAFA-NVMPEGNIGVIGASGTGIQ 207
                 +  ++  R R  G +++GP+C   + + T L FA N +P G + ++  SG    
Sbjct: 108 GPEGRALQDRVVDRVRSAGAVLLGPNCLGVIDSTTNLTFASNPLPGGRVALLSQSGNMAL 167

Query: 208 ELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKP-PAEA 266
           E+   +   G G +    LG +        +     ++   A   ++++A   +      
Sbjct: 168 EVSGFLQSRGHGFSRFASLGNQ------ADLGVADLIDSCVAHNGTDLIALYCEDFGDGR 221

Query: 267 VRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLL 315
             +    A  A  KP + L +G + A  R       +   ++A +    
Sbjct: 222 SFVSAAAAAAAANKPVLLLTVGGSEASVRGAQSHTGALTSDSAVIDAAC 270


>UniRef50_Q2LVF9 Acetyl-CoA synthetase beta subunit n=1 Tax=Syntrophus
           aciditrophicus SB RepID=Q2LVF9_SYNAS
          Length = 701

 Score = 58.1 bits (139), Expect = 8e-07,   Method: Composition-based stats.
 Identities = 37/213 (17%), Positives = 77/213 (36%), Gaps = 28/213 (13%)

Query: 111 ACQKLPDA-NLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEI------QLKTR 162
           + + +P+A +LA+I +A  +      Q   + ++ +M+ S      DE        +++ 
Sbjct: 56  SIKDIPEAVDLAIIFIAAVHVPAALEQCAIKGVSGIMIESGGFAEADEKGKSLQDAIRSF 115

Query: 163 AREKGLLVMGPDCGTSM--IAGTPLAFAN------VMPEGNIGVIGASGTGIQELCSQIA 214
               G+ V GP+C   +  I G   +F +       +  G + +I  SG         I 
Sbjct: 116 VERTGIRVWGPNCMGLVDGIRGHIFSFTDPKVLPFCLHPGPVSLIVQSGMLSAGFVIDIL 175

Query: 215 LAGE-GITHAIGLGGR-DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIV 272
             G  G +    +G + D+            L  L  D  +  +    +  +     + +
Sbjct: 176 SHGITGFSKVCSIGNKADIDES-------DVLSFLLEDPDTRCVGLYLE--SFVNGRRFM 226

Query: 273 NAMKATGKPTVALFLGYTPAVARDENVWFASSL 305
           +  + + KP +    G       +  V   +SL
Sbjct: 227 DLCRKSDKPVIV-LKGGRSRKGAEAAVSHTASL 258


>UniRef50_B6R8H6 N-acetyltransferase n=1 Tax=Pseudovibrio sp. JE062
           RepID=B6R8H6_9RHOB
          Length = 905

 Score = 58.1 bits (139), Expect = 8e-07,   Method: Composition-based stats.
 Identities = 75/466 (16%), Positives = 141/466 (30%), Gaps = 67/466 (14%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQLAQGSGS--SQALTQVRRWDSACQKLPDANLAL 122
           +AI    +   +  Q ++  +E +     +        +    +   S  +    A+LA+
Sbjct: 15  IAIVGPNSKQEVILQRLIDSIESSGFSGPKTFVGLPDASADGFKGVASIAEVESKADLAI 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMF--SDNVTLEDEI--QLKTRAREKGLLVMGPDCGTS 178
           +      AAE   Q  ++    ++   S   +  DE    L   A    + ++GP     
Sbjct: 75  LLGDHTTAAEDIKQLGEQGTRAVVIPASGFDSWRDEHLDALLKAAHPFNIRILGPGSLGI 134

Query: 179 MIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREV 235
               + L+         +G + +I  SGT      +       G +  + LG R L  +V
Sbjct: 135 ASPHSKLSTLLTSEQALKGELALISRSGTIFNTTLAWAKANSIGFSGVVSLG-RRLDVDV 193

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVAR 295
                   L+  + D +++ +    +  A   +        A  KP + +  G +     
Sbjct: 194 S-----DLLDWYAQDYRTKAILVHLETIANPRKFMSAARAAARSKPVIVIRSGASRDQHI 248

Query: 296 DENVWFASSLDEAARLACLLSRVTARR--------------NAIAPVSSGFICGLYTGGT 341
                 +      +     L R    R                +AP +   +  +  G +
Sbjct: 249 SGTAHSSRLATRDSVYDAALQRAGVLRVYDLDEMFEAAETITRVAPSAGRRLSIIANGRS 308

Query: 342 LAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLI 401
           LA  AA  LA   G  A  + +    L + +                    D    N ++
Sbjct: 309 LATLAADRLAKVGGKLAPISEETKEKLVSLTRT------------------DARADNPMV 350

Query: 402 ADLGAKPQ-----VRVLLLD-VVIGFGATADPAA-----SLVSAWQKACAARLD--NQPL 448
               A P+     +  LL D    G  A A P A      +  A  +A         +  
Sbjct: 351 LQEAASPEEFKEGISALLKDPNSDGVLAIAAPTAFEDFTEIAKALAEAGKEDRKRLGKHQ 410

Query: 449 YAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH 494
             + T+ G    P         L++A +    S   A      L+ 
Sbjct: 411 AFVTTLAGGANIP------RQVLDEARVPCYPSPSGAIRSFMHLVR 450


>UniRef50_B8FGY7 CoA-binding domain protein n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FGY7_DESAA
          Length = 709

 Score = 58.1 bits (139), Expect = 8e-07,   Method: Composition-based stats.
 Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 11/146 (7%)

Query: 156 EIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMP----EGNIGVIGASGTGIQELCS 211
           E QL   A + G+  +GP+C     +  P   A V P     G + +   SGT + +  +
Sbjct: 117 EKQLLETADKHGIRFLGPNCMGVFNSQYPFN-ATVTPFQDKPGFLSIASQSGTYLAQTLT 175

Query: 212 QIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKI 271
            +   G  +  A+ +G          I+ +  LE L  D K++ +    +  ++  R   
Sbjct: 176 YLKYRGVRLNQAMSVGNE------ANINIVDCLEYLGEDPKTKAIGLYIEALSDPGRFLE 229

Query: 272 VNAMKATGKPTVALFLGYTPAVARDE 297
           V    +  KP VA ++G + A A+  
Sbjct: 230 VAREVSRVKPIVAQYVGGSKAGAKSG 255


>UniRef50_Q0W3R5 Acetyl-coa synthetase (ADP-forming), alpha subunit n=2
           Tax=Euryarchaeota RepID=Q0W3R5_UNCMA
          Length = 460

 Score = 58.1 bits (139), Expect = 9e-07,   Method: Composition-based stats.
 Identities = 40/224 (17%), Positives = 82/224 (36%), Gaps = 27/224 (12%)

Query: 117 DANLALISVAGEYAAELANQALDRNL-NVMMFSDNVT------LEDEIQLKTRAREKGLL 169
           + +L ++ V  + A  + +    + +  + + +   +         E  LK +A+  G+ 
Sbjct: 69  EVDLGVVIVPAQAAPSVIDDCGRKGVGALCVITSGFSEVGKEGAALEEDLKKKAKAYGMR 128

Query: 170 VMGPDCGTSMIAGTPLAFANVMP----EGNIGVIGASGTGIQELCSQIALAGEGITHAIG 225
           ++GP+    +     L  A+++P     G I  I  SG     L      +  G+   I 
Sbjct: 129 MLGPNTMGFVNRSISLN-ASIVPRMPYRGEISFISQSGALGLALTDWSIGSRLGLNCIIS 187

Query: 226 LGGR-DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
            G + D+S           LE    DE +  ++   +        + + A     KP +A
Sbjct: 188 TGNKADVSEA-------DLLEYFDQDEDTWTISMYIE--GLKDGRRFIEAASKVKKPMLA 238

Query: 285 LFLGYTPAVARDENVW-----FASSLDEAARLACLLSRVTARRN 323
           +  G + A AR           + ++ ++A   C + RV     
Sbjct: 239 IKAGVSQAGARAAASHTGSLAGSDAVYDSAFRQCGVIRVEGVEE 282


>UniRef50_B8FN91 CoA-binding domain protein n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FN91_DESAA
          Length = 694

 Score = 58.1 bits (139), Expect = 9e-07,   Method: Composition-based stats.
 Identities = 53/283 (18%), Positives = 101/283 (35%), Gaps = 56/283 (19%)

Query: 111 ACQKLPD-ANLALISVAGEYAAELANQALDRNLNVMM-----FSDNVT----LEDEIQLK 160
           + + +PD  +LA++ V  +   ++  +  +R +  +M     FS+       L+DE+   
Sbjct: 57  SVKDVPDPVDLAILFVPAKAVPKMVEECGERGIRAVMIQSAGFSETGPEGKALQDEVD-- 114

Query: 161 TRAREKGLLVMGPDCGTSM--IAGTPLAFANV------MPEGNIGVIGASGTGIQELCSQ 212
             A+  G+ V GP+C   +  +     +FA           GN+ +I  SG         
Sbjct: 115 AVAQRHGIRVWGPNCLGMVDSVNHNVFSFAAPSMWDVGHIPGNVSLIVQSGMLA--GGFL 172

Query: 213 IALAG---EGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRL 269
           I        G++    +G +    E         LE L +D  ++ +    +  A     
Sbjct: 173 IDNMSHGTMGMSKVCSIGNKSDVDEC------DLLEYLISDPDTQAIGMYLE--AIPRGR 224

Query: 270 KIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNA----- 324
           +     + + KP V L  G + A A+      AS   + A ++ +L++            
Sbjct: 225 RFAELCRQSPKPIVVLKGGTSTAGAKAAASHTASMSGDGAIVSGVLAQCGVVEARDFKQM 284

Query: 325 --------IAPVSSGFICG-----LYTGGTLAAEAAGLLAGHL 354
                   I P     + G      Y+GG     A  + A  +
Sbjct: 285 LDICRAFGITPEMPPEMRGRTAILTYSGG-----AGIMAADFV 322


>UniRef50_UPI0001B555C7 CoA-binding protein n=1 Tax=Streptomyces sp. AA4
           RepID=UPI0001B555C7
          Length = 672

 Score = 58.1 bits (139), Expect = 9e-07,   Method: Composition-based stats.
 Identities = 54/237 (22%), Positives = 90/237 (37%), Gaps = 25/237 (10%)

Query: 96  SGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNL-NVMMFS------ 148
           S     L  VR   S  +     +L +++   E    L  QA D     V++F+      
Sbjct: 46  SRGPLDLPGVRTVGSLAEIGYGPDLVVLATPAETVPALVRQARDLGSGAVIVFASGFAEG 105

Query: 149 DNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVM-------PEGNIGVIGA 201
            N  LEDE++    A +  L V+GP+C   +     +  +  +       P G I ++  
Sbjct: 106 GNAVLEDELR--EAAGD--LPVLGPNCLGVVSHPAGVQLSTTVFLDRDRVPPGPIAIVTQ 161

Query: 202 SGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSK 261
           SG     L   +  AG G ++   +G      E    S     ++L      EVL    +
Sbjct: 162 SGAMGFVLADLLEQAGIGYSYYASVG-----NEACLSSHEIGSDLLEQ-PDVEVLVLYLE 215

Query: 262 PPAEAVRLKIVNA-MKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSR 317
              +A  L+ +    +A GK  VAL +G + A  +      A+   +   LA L  +
Sbjct: 216 GVRDADGLRALGRQARAAGKTVVALAVGSSAAGRQAALSHTAAVAGDHFLLASLCRQ 272


>UniRef50_A1WNK8 CoA-binding domain protein n=4 Tax=cellular organisms
           RepID=A1WNK8_VEREI
          Length = 711

 Score = 57.8 bits (138), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 46/232 (19%), Positives = 82/232 (35%), Gaps = 25/232 (10%)

Query: 88  ALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMM- 146
           AL  +   +     L   R        +   +LA++ V  E+        +++ +   + 
Sbjct: 56  ALYPINARATELMGLPAYRTLPDCPAAV---DLAILLVPREHVYAAIEDCVEKEVGCALC 112

Query: 147 ----FSDNVT--LEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVM--------P 192
               F++       DE  L   AR  G+ ++GP+C   M     L     +        P
Sbjct: 113 ITAGFAETGPKGCADEQALVALARAGGVRLIGPNCMGLMNTHHRLCATTAVVMGGIDTLP 172

Query: 193 EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEK 252
            G IG+   SG  +  + S+    G G +  I +G +        +      E L  D  
Sbjct: 173 AGGIGLASQSGALMGAMISRGVDIGTGFSSTISVGNQ------SDLDLNDFFEYLIDDPM 226

Query: 253 SEVLAFVSKPPAEAVRLK-IVNAMKATGKPTVALFLGYTPAVARDENVWFAS 303
           ++V+    +   +A R   ++    A  KP   +  G + A AR      AS
Sbjct: 227 TDVVCLYMEAVKDAPRFTALLARAAAVRKPVCIVKSGRSEAGARAAASHTAS 278


>UniRef50_Q89GG9 Bll6376 protein n=1 Tax=Bradyrhizobium japonicum RepID=Q89GG9_BRAJA
          Length = 750

 Score = 57.8 bits (138), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 50/260 (19%), Positives = 97/260 (37%), Gaps = 24/260 (9%)

Query: 66  VAIRSEAADAGIAQA-IMQQLEEALKQLAQGSGSSQ--ALTQVRRWDSACQKLPDANLAL 122
           VAI   + D+       ++ L EA    A    + +   +  +R +          +LA+
Sbjct: 45  VAIIGASNDSNRIGGRPLRYLREAGFAGAVYPVNPRRNEVQGLRAYADVRDIPGPVDLAI 104

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVT------LEDEIQLKTRAREKGLLVMGPDC 175
           + V+ +   E      ++ +   ++FS             + +++  AR  G+ ++GP+C
Sbjct: 105 VIVSADLVVETIEACAEKGIGCAIIFSSGFAEVGPEGARRQQRIEEIARAAGMRLLGPNC 164

Query: 176 GTSMIAGTPL------AF-ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
             +  + +        AF   VM  G +GV+  SG     L         GI H I  G 
Sbjct: 165 LGAFNSHSGFFGTFTQAFDTGVMFPGELGVVSQSGAAGAHLAYMCRQRCIGIGHWITTGN 224

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRL-KIVNAMKATGKPTVALFL 287
                    I     +E ++     +V+A   +      R  + + A +  GKP +A+ +
Sbjct: 225 E------ADIEVSECVEWMAHAPHVKVIALFVEAIRNGPRFVRALEAAREHGKPVIAIKV 278

Query: 288 GYTPAVARDENVWFASSLDE 307
           G + A A        + + E
Sbjct: 279 GRSAAGALAAASHTGALVGE 298


>UniRef50_Q3JJ59 Acetyltransferase, GNAT family n=65 Tax=Proteobacteria
           RepID=Q3JJ59_BURP1
          Length = 1024

 Score = 57.8 bits (138), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 55/332 (16%), Positives = 94/332 (28%), Gaps = 49/332 (14%)

Query: 168 LLVMGPDCGTSMIAGTPLAF---ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           L V+GP     +       F   A ++  G +  +  S      +       G G +HA+
Sbjct: 361 LRVVGPGSLGVVSPALGAHFGAPACIVKAGGVAWVSQSNALTNAVLGWAHARGLGFSHAV 420

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
            LGG         + A   L+ L++D ++  +         A +        A  KP +A
Sbjct: 421 ALGGE------ADVDAADVLDYLASDAETRAILLELDTVKSARKFMSAARAAARNKPVLA 474

Query: 285 LFLGYT-------PAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLY 337
           L  G          A  +   +    +LD+       L    A   +          G+ 
Sbjct: 475 LRAGRGDSGDLLYTAAFQRAGMVRVDALDDLLDEIEALGVGRAAATSGGVTLVTSDRGV- 533

Query: 338 TGGTLAAEAAGLLAGHLGVEA----DDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID 393
               LA +A       L        D+            + ++ LGDD            
Sbjct: 534 --AKLAVDALAAAGETLAQWPRAAVDEVGGALPAGIVAGNPLL-LGDDA----------R 580

Query: 394 PTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIAT 453
           P      +  L   P    +    V+   + + PA  +     ++               
Sbjct: 581 PEYFGAALKALAQHPPTGTV---FVVHATSHSAPAVDVARVLIESRKFARRGMLACFFGG 637

Query: 454 VTGTERD------------PQCRSQQIATLED 473
           V    RD            PQ  ++  A L D
Sbjct: 638 VDAATRDALHVHGIPVHTTPQRLARAHARLVD 669


>UniRef50_A4FCG4 Acyl-CoA synthetase (NDP forming type) n=2 Tax=Actinomycetales
           RepID=A4FCG4_SACEN
          Length = 892

 Score = 57.8 bits (138), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 43/238 (18%), Positives = 94/238 (39%), Gaps = 17/238 (7%)

Query: 65  CVAIRSEAAD-AGIAQAIMQQLEEALKQLAQGSGS--SQALTQVRRWDSACQKLPDANLA 121
           CVA+     D + +  A+ +++  A  +      +  ++ +  +  +    +     +L 
Sbjct: 197 CVAVVGAGRDRSSVGNAVFRKVLAAGFRGNCYPVNRHARTVESLPAFADVEELPEVPDLV 256

Query: 122 LISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQ--LKTRAREKGLLVMGPDCGTS 178
           ++ V  E   ++A     + +  +++ S  VT +  +   L    R  G+ ++GP+C   
Sbjct: 257 VVCVPAEAVPQVAESCGRKGVRALVVVSAGVTSDPVLAHGLVDAVRRWGMRLVGPNCLGV 316

Query: 179 MIAGTPLAF-----ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
           +     +       +   P G++GVI  SG     L   +A  G G++  + +G      
Sbjct: 317 INTDPDVRLDATFTSGCAPAGDVGVITQSGGVGIALLDGLAACGLGVSSVVSVGD---KY 373

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
           +V G      L     DE++ +     +      +   ++   A GKP + L  G +P
Sbjct: 374 DVSGNDM---LLWWQRDERTRLAVVYLESFGNPRKFSWLSRRMARGKPVIVLKSGASP 428


>UniRef50_A9ISQ2 Acetyl-CoA synthetase n=4 Tax=Burkholderiales RepID=A9ISQ2_BORPD
          Length = 1113

 Score = 57.8 bits (138), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 36/211 (17%), Positives = 80/211 (37%), Gaps = 21/211 (9%)

Query: 96  SGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNL-NVMMFSDNVT-- 152
           +  ++ +  +  + S        +LA+ ++    A    + A+   + N++MFS      
Sbjct: 48  NAGARQVQGLAAFASLRAVGRPIDLAIFAIPASGADAALDDAIAAGVRNIVMFSAGFAEL 107

Query: 153 ----LEDEIQLKTRAREKGLLVMGPDCGTSM-------IAGTPLAFANVMPEGNIGVIGA 201
               +  +     +AR  G+ V+GP+C   M          +P+     +  G +G++  
Sbjct: 108 GEQGVAAQSAFAAKARAAGIRVLGPNCLGFMNVARSVYATFSPVVSTGRVEAGPVGLVSQ 167

Query: 202 SGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSK 261
           SG       +     G G++  +  G          I     +  ++ D  + V+    +
Sbjct: 168 SGAFGAYAYAMARERGVGLSMWVTTGNE------SDIDVADCIAWMARDPATRVIMAYLE 221

Query: 262 PPAEAVR-LKIVNAMKATGKPTVALFLGYTP 291
              +  +  + +   +A GKP VA+ +G T 
Sbjct: 222 GCRDGAKLRQALELARAAGKPVVAVKVGRTA 252


>UniRef50_Q7WC02 Putative acyl-CoA synthetase n=2 Tax=Bordetella RepID=Q7WC02_BORPA
          Length = 710

 Score = 57.8 bits (138), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 43/213 (20%), Positives = 81/213 (38%), Gaps = 22/213 (10%)

Query: 115 LPDA-NLALISVAGEYAAELANQALDRNLN--VMMFSDNVTLEDE-----IQLKTRAREK 166
           LP A +L ++++  +   +  +   D      +++ S      DE      QL   AREK
Sbjct: 81  LPQAPDLVILAIPRDLVVQAVSDCGDIGAKGVIVVASGFSESGDEGARLEQQLLAVAREK 140

Query: 167 GLLVMGPDCGTSMIAGTPLAFANVMP-------EGNIGVIGASGTGIQELCSQIALAGEG 219
            + ++GP+C   +      + A  +         G+IG+I  SG  +  +  +      G
Sbjct: 141 AVRIIGPNCVGVVSPAHGFSLATTVSLVDRAPLPGHIGLISQSGAVMGTMIDRGISQNVG 200

Query: 220 ITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVL-AFVSKPPAEAVRLKIVNAMKAT 278
            +H I +G +        +     ++ +  D  + V+  +V       + L+     +A 
Sbjct: 201 FSHCISVGNQ------ADVDFCDFVDFMIDDPGTHVICTYVEGIKRPDLFLRAAGRAQAA 254

Query: 279 GKPTVALFLGYTPAVARDENVWFASSLDEAARL 311
            KP + +  G T A A       AS     A L
Sbjct: 255 SKPWLLMKSGRTEAGAASAFSHTASLASNQAIL 287


>UniRef50_UPI0001C30E25 CoA-binding domain protein n=1 Tax=Conexibacter woesei DSM 14684
           RepID=UPI0001C30E25
          Length = 904

 Score = 57.8 bits (138), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 48/265 (18%), Positives = 92/265 (34%), Gaps = 21/265 (7%)

Query: 66  VAIRSEAADAGIAQAIMQQ---LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+     DA      +            L       +A+   R + S  +   + +LA+
Sbjct: 210 IAVLGATHDAATIGGAVFANLVASGYTGALHAVERRGRAIGSHRCYRSLDEVPDEIDLAV 269

Query: 123 ISVAGEYAAELANQALDRNLNVMM-----FSDNVT--LEDEIQLKTRAREKGLLVMGPDC 175
           ++V        A    +R +  +      F+++       + +L    R  G+ ++GP+C
Sbjct: 270 LAVPAGEVLGAARACGERGVRALAVLAAGFAESGPDGAARQRELLRACRGAGMRLVGPNC 329

Query: 176 GTSMIAGTPL----AFANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
              +     +     FA   P  G IG++  SG     L  Q    G G++  + +G   
Sbjct: 330 LGVLNTDPRVRLDATFAPSHPPAGGIGLLSQSGGVGIALLEQARALGIGVSTFVSVGN-- 387

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
              ++ G      LE    DE++  +    +      +   +       KP VA+  G T
Sbjct: 388 -KADLSGNDF---LEWSEQDERTRAILLYLESFGNPRKFARIARRVGQRKPIVAVKAGRT 443

Query: 291 PAVARDENVWFASSLDEAARLACLL 315
            A AR  +    + L  +      L
Sbjct: 444 AAGARAASSHTGALLASSELAVAAL 468


>UniRef50_A9BTY3 CoA-binding domain protein n=8 Tax=cellular organisms
           RepID=A9BTY3_DELAS
          Length = 729

 Score = 57.8 bits (138), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 54/284 (19%), Positives = 101/284 (35%), Gaps = 39/284 (13%)

Query: 57  NNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLP 116
            +ATP  +  ++       G A  I       +                R   ++  +LP
Sbjct: 28  ASATPGALGASVLGNLERNGFAGDI-----HLINPKRSEIAG-------RACLASVDQLP 75

Query: 117 DA-NLALISVAGEYAAELANQALDRNL--NVMMFSDNVT------LEDEIQLKTRAREKG 167
           +  ++A++++   +      +AL        ++FS          + ++ ++   A E G
Sbjct: 76  EGVDVAVLAIPQPFVL-ETVRALAARRVGAAVIFSAGFAEAGERGMAEQREIARIAAEAG 134

Query: 168 LLVMGPDCGTSM--IAGTPLAFANV--------MPEGNIGVIGASGTGIQELCSQIALAG 217
           ++V GP+C   +  +   PL F  V             IGV+  SG  +  LC+ +A   
Sbjct: 135 MVVEGPNCLGCINYLQRVPLTFVEVNIDAQQADATRPAIGVVSQSGAMMTVLCTTLASRA 194

Query: 218 EGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKP-PAEAVRLKIVNAMK 276
             ++HAI  G    S           ++ L     + V+A + +     A  L  V   +
Sbjct: 195 LPLSHAISTGNEAASHA------EDYVDFLLEQPSTRVVAMIVEQFRQPARILAAVARAR 248

Query: 277 ATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTA 320
           + GK  V L  G + A          +   + A +   L R  A
Sbjct: 249 SLGKSVVLLHPGKSSAARASAATHTGAMAGDYALMRTKLERAGA 292


>UniRef50_Q2LUQ3 Acetyl-CoA synthetase / acetyltransferase (GNAT) family protein n=4
           Tax=Bacteria RepID=Q2LUQ3_SYNAS
          Length = 918

 Score = 57.8 bits (138), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 40/271 (14%), Positives = 82/271 (30%), Gaps = 22/271 (8%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDA----NLA 121
           VA+   +   G    I+      L+   +         +V       + + D     +LA
Sbjct: 28  VALIGASDREGSVGRII--FTNLLQAKDRKIFPVNPKKKVILGRKCFENIADISEPVDLA 85

Query: 122 LISVAGEYAAELANQALDRNLN--VMMFSDNVTLEDEIQLKTRA-----REKGLLVMGPD 174
           +I+   +   EL        +   V++ +    + +E +L         ++ G+ ++GP+
Sbjct: 86  VIATPAKEVPELVEDCGRAGIGGLVIISAGFKEIGEEGRLLEERITASRKKYGMRILGPN 145

Query: 175 CGTSMIAGTPLA---FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
           C   +     L         P G+I  I  SG     +         G +    LG    
Sbjct: 146 CLGFVRPNEGLNATFLKTNPPPGHIAFISQSGALGSAILDWAVNEHVGFSMFASLG---- 201

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
              +  +     ++ L  D  +  +    +    A +        A  KP + +  G   
Sbjct: 202 --AMSDVDFGDLIDFLGEDPDTRSILLYMEGVGNAKKFMSAARAFAMRKPIIVIKPGRFT 259

Query: 292 AVARDENVWFASSLDEAARLACLLSRVTARR 322
             A+       +   + A       R    R
Sbjct: 260 ESAQAARSHTGAMAGDDAIYEAAFKRAGVLR 290


>UniRef50_C1RIS6 Acyl-CoA synthetase (NDP forming) n=1 Tax=Cellulomonas flavigena
           DSM 20109 RepID=C1RIS6_9CELL
          Length = 707

 Score = 57.8 bits (138), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 63/333 (18%), Positives = 120/333 (36%), Gaps = 45/333 (13%)

Query: 111 ACQKLPDANLALISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEI--QLKTRA 163
           + ++  D +LA++ V  +        A        +     F+++      +  ++   A
Sbjct: 68  SLREASDVDLAVLVVPPDAVPGALEDARAAGTRAAVVCAGGFAESGPAGARVQERVVAVA 127

Query: 164 REKGLLVMGPDCGTSMIAGTPLAFANVMP------EGNIGVIGASGTGIQELCSQIALAG 217
           RE G+ ++GP+  +  +       AN MP       G +G++  SG     L   +A AG
Sbjct: 128 REAGIRLLGPNT-SGFVNPVDRTTANFMPAVADLPPGTVGLVAQSGGVNLALAFLLARAG 186

Query: 218 EGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKA 277
            G+   +GLG          +     L+ L+ D+ +  +    +  A+   L        
Sbjct: 187 VGLRLGVGLG------NAVDVDFPEVLDHLALDDATTAVGLHVEGVADGPALLAALRRTT 240

Query: 278 TGKPTVALFLGYTP----AVARDENVWFASSLDEAARLAC----------LLSRVTARRN 323
             KP VAL +G +     A +    +  + ++  AA              L++ + A R+
Sbjct: 241 ARKPVVALKVGRSDVSEFARSHTGALTGSYAVTRAALQQSGAVVVDSLEELVAALVALRS 300

Query: 324 AIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQII---DLGD 380
              P ++    GL TG    A    +++  LG     + +        S   +       
Sbjct: 301 VRLPAAARIGVGLVTG---QAGPGLVVSDSLGARESRSGRSLTRPSCGSPSCVPPLTFQR 357

Query: 381 DFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVL 413
           +    GRP P   P +R      +   P V V+
Sbjct: 358 NPVDTGRPSPTFGPVVRT-----VLDDPGVDVV 385


>UniRef50_B5IDQ5 CoA binding domain protein n=2 Tax=Aciduliprofundum boonei T469
           RepID=B5IDQ5_9EURY
          Length = 464

 Score = 57.0 bits (136), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 43/237 (18%), Positives = 83/237 (35%), Gaps = 21/237 (8%)

Query: 117 DANLALISVAGEYAAELANQALDRNLNVMMFSDNVT------LEDEIQLKTRAREKGLLV 170
           + +L++I++  E   ++      ++  ++  +           E E ++   A++    +
Sbjct: 65  EVDLSVITLPAEVTVKIFEDVAKKSKFIIPIAGGFGETGKEGKERERKILEIAKKYNARI 124

Query: 171 MGPDCGTSMIAGTPLAFANVMPE-------GNIGVIGASGTGIQELCSQIALAGEGITHA 223
           +GP+     I  T +  A V+PE       G+I  I  SG         +++   G +  
Sbjct: 125 IGPNTVGIYIPSTGVNTALVVPERSRFPGDGDIAFITQSGALGLLTMDSVSMYDVGFSSF 184

Query: 224 IGLGGR-DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPT 282
           I LG R D++           L+    DEKS+V+    +  A       V    +  KP 
Sbjct: 185 INLGNRVDVNEN-------ELLQYFGEDEKSKVIIMYIESFANGREFMRVAKNVSRKKPI 237

Query: 283 VALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTG 339
           V L  G T    +  ++   +     A       +    R         +   L  G
Sbjct: 238 VVLKAGRTKRGGKAASLHTGALGGSDAVADGAFKQCGVIRAYDEIELVDYARALAYG 294


>UniRef50_C8WUT7 CoA-binding domain protein n=2 Tax=Alicyclobacillus acidocaldarius
           RepID=C8WUT7_ALIAD
          Length = 637

 Score = 57.0 bits (136), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 43/227 (18%), Positives = 83/227 (36%), Gaps = 21/227 (9%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNL-NVMMFSDNVTLED- 155
           S+Q++  VR + S        +LA++ V       + +  +   + +VM+ S   +  D 
Sbjct: 48  SAQSVAAVRAYPSLRDVPEPVDLAVLVVPASQVLSVIDDVIAAGIKHVMILSSGFSDMDK 107

Query: 156 -----EIQLKTRAREKGLLVMGPDCGTSMIAG----TPLAFANVMPE-GNIGVIGASGTG 205
                E ++  + R  G  ++GP+    +          +FA  +PE G++ +   SG  
Sbjct: 108 PGEELEREISEKLRAAGCRLIGPNSLGLIQMDSETRLNASFAPKVPEYGHVAIASHSGAL 167

Query: 206 IQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAE 265
              +    A  G G+   + LG R    +V G   L        D   E++    +    
Sbjct: 168 GITILDYAAYIGLGVASFVSLGNR---ADVSGNDLLQ---YWGDDPAIEMILLYLESFGN 221

Query: 266 AVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLA 312
                 +       KP +A+    +       +V  A ++  AA  A
Sbjct: 222 PRNFSRLARRITRQKPILAV---KSARTPVGHDVANARTVSVAAEDA 265


>UniRef50_B7X585 CoA-binding domain protein n=2 Tax=Comamonas testosteroni KF-1
           RepID=B7X585_COMTE
          Length = 707

 Score = 57.0 bits (136), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 71/447 (15%), Positives = 133/447 (29%), Gaps = 97/447 (21%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQG--SGSSQALTQVRRWDSACQKLPDANLALI 123
           VA+      +  ++     L+    +      + S   +   + + +A       ++AL+
Sbjct: 17  VALVGATDRSTWSKMAFDNLKLLGFEGKVHLVNRSGGVVHGQQSFKTAVDIGESVDVALL 76

Query: 124 SVAGEYAAELANQALDRNLNVMMF---------SDNVTLEDEIQLKTRAREKGLLVMGPD 174
            V      +         +   +          S+  T+++  ++   ARE G+ ++GP+
Sbjct: 77  MVPNPAMEDALRDLGAAGIRHAVVLAGGFAETGSEGRTMQE--RMVATARELGITLLGPN 134

Query: 175 C-GTSMIAGTPLAFANVMP----EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
           C G        + +   M     +G I ++  SG     +       G G+      G  
Sbjct: 135 CLGFINFTTGAVCWTGAMRTPPLKGGISIVSQSGAVATVMKHFAHQHGVGMNVVAATG-- 192

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIV-----NAMKATGKPTVA 284
             +  + G+     ++ L  DE ++V+A      AE VR   +         A  KP V 
Sbjct: 193 --NEAMLGL--AECVDYLVDDESTKVIAVF----AETVRDTRLFRAAAERALAKAKPIVV 244

Query: 285 LFLGYTPAVARDE---------------------NVWFASSLDEAARLACLLSRVTARRN 323
           L +G +    +                        +    S++E    A LL +      
Sbjct: 245 LKVGRSDIATQAAQSHTGSLVGDDSVFDGVCRQLGLVRVRSIEELVFTAALLEKTGVLAE 304

Query: 324 AIAPVSSGFICGLYTGG-----------------TLAAEAAGLLAGHLGVEADDTHQHGM 366
               V S       +GG                  L+ E    L   L   A        
Sbjct: 305 GGVAVLSS------SGGMGELAADYAQLETLRLPALSNETLSALREILPPMATPA----N 354

Query: 367 MLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATAD 426
            LD     + D                P L  + +  +   P V VL+    +      D
Sbjct: 355 PLDLTGAVVND----------------PALFTRCMDAMQRDPAVSVLVCVADVPTANNND 398

Query: 427 PAASLVSAWQKACAARLDNQPLYAIAT 453
            A   V   Q     + D +  Y + +
Sbjct: 399 WAPFAVGTLQAIGQFKPDGRARYLVVS 425


>UniRef50_A3U075 CoA-binding n=1 Tax=Oceanicola batsensis HTCC2597
           RepID=A3U075_9RHOB
          Length = 727

 Score = 57.0 bits (136), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 43/234 (18%), Positives = 79/234 (33%), Gaps = 22/234 (9%)

Query: 104 QVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLE-------DE 156
            ++ WD+  +     ++  I++ GE   + A  A+      +M       E        E
Sbjct: 72  GLKAWDNVAELAEAPDVTAINLPGEMVLDAARDAIAAGTKALMIHSGGFGERGADGEARE 131

Query: 157 IQLKTRAREKGLLVMGPDCGTSMI----AGTPLAFANVMPEGNIGVIGASGTGIQELCSQ 212
            +LK    E G+  +GP+C   M     A      A  + +G + +I  SG+    +  Q
Sbjct: 132 AELKALCAEAGVAALGPNCLGIMSLTRKASVSSFKAGKLGQGPLALISQSGSVA-SILMQ 190

Query: 213 IALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLA-FVSKPPAEAVRLKI 271
           IA    G +     G   ++      +A   +     D  + ++  FV           +
Sbjct: 191 IAQP-FGASLVASTGNEAVT------TAEDLMHHAIEDPDTRIIVGFVEALRRPEQLFGL 243

Query: 272 VNAMKATGKPTVALFLGYTPAVARDENVW--FASSLDEAARLACLLSRVTARRN 323
               +A GKP + L  G T              +   E  R A   + +    +
Sbjct: 244 AWKARAAGKPIILLKAGLTAKGGEVSRGHTGALAGSGEVYRQALAQAGIVMAED 297


>UniRef50_Q2Y8E7 GCN5-related N-acetyltransferase n=2 Tax=Betaproteobacteria
           RepID=Q2Y8E7_NITMU
          Length = 889

 Score = 57.0 bits (136), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 39/210 (18%), Positives = 72/210 (34%), Gaps = 13/210 (6%)

Query: 120 LALISVAGEYAAELANQALDRNLNV-MMFSDNVTLED---EIQLKTRAREKGLLVMGPDC 175
           LA+I+   +    +     +  +   ++ +     E    E QL   AR  G+ ++GP+C
Sbjct: 72  LAVIATPPQTVPGIIENCGNEGVKAAIIITAGFQEEGDRLEEQLLATARAFGIRLVGPNC 131

Query: 176 GTSMIAGTPLA---FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
              M     L    +      GNI  +  SG     +         G +  + +G     
Sbjct: 132 LGIMRPSIGLNATFYKGGANSGNIAFVSQSGALCTAILDWAQNNDVGFSSIVSMGSS--- 188

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                +     L+ L AD  ++ +    +   +A R           KP + + +G   A
Sbjct: 189 ---TDVDFGEILDYLVADTATQSILMYIEGIRDARRFMSALRAATRLKPVIVVKVGRHAA 245

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARR 322
            A+      A+ +         L+RV A R
Sbjct: 246 GAKAARSHTAALVGADNVFNAALNRVGAVR 275


>UniRef50_Q64CM7 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           GZfos1D1 RepID=Q64CM7_9ARCH
          Length = 448

 Score = 57.0 bits (136), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 37/220 (16%), Positives = 80/220 (36%), Gaps = 25/220 (11%)

Query: 119 NLALISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGP 173
           +L +I+V  E    +  +   + +  ++     FS+    E E ++   AR+  + ++GP
Sbjct: 67  DLGIIAVPAEIVPAVLEECGRKGIRGVVIVSAGFSEIGNSELENKVSDIARDYEMRMIGP 126

Query: 174 DCGTSMIAGTPLAFANVMPE----GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
           +    +     L  A+++P+    G I  +  SGT    L    A    G+   +G+G +
Sbjct: 127 NTFGFINTHLNLN-ASIIPQMPVIGGISFVTQSGTFGLALVDWAASQQMGLHLVVGVGNK 185

Query: 230 -DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA---- 284
            D+            L  LSAD  ++ +    +        + ++      KP +A    
Sbjct: 186 ADVDDS-------DILAYLSADRHTKTIMMYIE--GIERGRRFIDVASRIRKPVIALKTG 236

Query: 285 -LFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRN 323
               G    ++   ++     + + A     + R      
Sbjct: 237 RSLAGSKAVLSHTGSLAGTDRIYDGAFKQAGVIRAWTIEE 276


>UniRef50_B6AEK9 Acetyl-CoA synthetase, putative n=1 Tax=Cryptosporidium muris RN66
           RepID=B6AEK9_9CRYT
          Length = 966

 Score = 56.6 bits (135), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 65/446 (14%), Positives = 135/446 (30%), Gaps = 74/446 (16%)

Query: 104 QVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNL-NVMMFSDNVT------LEDE 156
             + +DS        +L +I    +    +  +A  + +  +++ S          ++ E
Sbjct: 80  GKKCYDSLLNIPVVIDLVVIVTPAKTVLGIVQEAAKKKVPAILIISSGFKESGPEGIDRE 139

Query: 157 IQLKTRAREKGLLVMGPDCGTSMIAGTPL--AFANVM-PEGNIGVIGASGTGIQELCSQI 213
             +   A++ G+ ++GP+C   M     L   F N M   G    +  SG     +    
Sbjct: 140 KAILDIAKKNGIRILGPNCLGFMNVAYNLNATFINCMACRGTTAFLSQSGALCAAVLDWA 199

Query: 214 ALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVN 273
                G +  + +G       +  I     ++ L  D  ++++    +    A +     
Sbjct: 200 VKVRIGFSAFVSVG------SMSDIDWGDLVDYLGHDPNTKIILMYIESIGNARKFLSAA 253

Query: 274 AMKATGKPTVALFLGYTPAVARDE---------------------NVWFASSLDEAARLA 312
              A  KP + +  G + A  +                        V    +++E    A
Sbjct: 254 KEIAISKPIIVIKAGKSRAAYKAAASHTGSLVGNYDAFISAMKRIGVLVVDTIEELFNCA 313

Query: 313 CLLSRVTARRNAIAPVSSGFICGLYTGG--TLAAEAAGLLAGHLGVEADDTHQHGMMLDA 370
            +L+++        P     +     GG   +AA+A  +  G L +  +        + +
Sbjct: 314 LVLNKMP------HPKGPKLLILTNAGGPAVIAADALDISGGELSILPNSIIDRIDQIAS 367

Query: 371 DSHQI---IDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADP 427
                   +D+  D           D       I  +    +V   LL +++      +P
Sbjct: 368 PGWSKCNPVDILGDATPQ-------DYVN----ILKILGDEEVGDGLL-IILSPQDITNP 415

Query: 428 ---AASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGI-AVVSSLP 483
              A  ++    K          +  I +  G        +     L  AGI  + +   
Sbjct: 416 TQVAELIIPIINKIKE------KIPVICSWMGANE----VAMGQEILVKAGIPEISNPDT 465

Query: 484 EATLLAAALIHPLSPAAQQHTPSLLE 509
            A   A    H         TP L +
Sbjct: 466 AAQTFALIWCHAKHLREVYETPHLED 491


>UniRef50_A8M7Y9 CoA-binding domain protein n=4 Tax=Micromonosporaceae
           RepID=A8M7Y9_SALAI
          Length = 909

 Score = 56.2 bits (134), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 28/134 (20%), Positives = 51/134 (38%), Gaps = 11/134 (8%)

Query: 156 EIQLKTRAREKGLLVMGPDCGTSMIAGTPLAF-ANVMP----EGNIGVIGASGTGIQELC 210
           + +L   A   G+ ++GP+C      GT +   A + P     G +G+   SG     L 
Sbjct: 327 QRRLVRAAHAAGMRIIGPNCLGVANTGTEVRLNATLAPRLPVPGRVGLFSQSGAFGVALL 386

Query: 211 SQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK 270
           +++   G G++  +  G R    +V G   L        D  ++V+    +      +  
Sbjct: 387 AEVDRRGLGLSSLVSAGNR---ADVSGNDLLQ---YWQDDPDTDVILLYLETFGNPRKFA 440

Query: 271 IVNAMKATGKPTVA 284
            +       KP VA
Sbjct: 441 RLARRIGREKPIVA 454


>UniRef50_C8QZV8 CoA-binding domain protein n=2 Tax=Desulfobulbaceae
           RepID=C8QZV8_9DELT
          Length = 699

 Score = 56.2 bits (134), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 44/207 (21%), Positives = 75/207 (36%), Gaps = 16/207 (7%)

Query: 104 QVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFS------DNVTLEDE 156
            +  W +        +L +I+V      E     L      V + +      D    E E
Sbjct: 54  GLPCWPTLKGAGAQIDLGVIAVPRSLVEEAVEDCLAAGARAVAVITAGFKEMDATGAELE 113

Query: 157 IQLKTRAREKGLLVMGPDCGTSMIAGTPL--AFANVMPE-GNIGVIGASGTGIQELCSQI 213
            +L  R R++ + ++GP+C   + +   L  +FA  MP  GNI VI  SG     +    
Sbjct: 114 KKLAARCRQQQVRLLGPNCLGLINSHHRLNASFAGEMPACGNISVISQSGALATAILDLA 173

Query: 214 ALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVN 273
           A    G+   + +G +    EV        L  L+ DE++ V+    +  +         
Sbjct: 174 AERHLGLAKLVSIGNKADLNEV------DLLSALTDDEQTGVIVAYLEDISSGDDFVKAA 227

Query: 274 AMKATGKPTVALFLGYTPAVARDENVW 300
              +  KP + L  G T A  +     
Sbjct: 228 TEASNHKPVIILKSGTTEAGRQAATSH 254


>UniRef50_B9B8Y3 CoA binding domain protein n=1 Tax=Burkholderia multivorans CGD1
           RepID=B9B8Y3_9BURK
          Length = 721

 Score = 56.2 bits (134), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 32/175 (18%), Positives = 55/175 (31%), Gaps = 16/175 (9%)

Query: 158 QLKTRAREKGLLVMGPDC--------GTSMIAGTPLAFANVMPEGNIGVIGASGTGIQEL 209
           +L   AR   + + GP+C        G +M              G + V+  SG     +
Sbjct: 123 RLVEIARRGAIRIAGPNCVGLANVRTGAAMNFMPDCGKMINGRSGRVAVVSQSGALGYTV 182

Query: 210 CSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRL 269
              +   G GI+H +  G          +     +  L+ D +   +  + +      R 
Sbjct: 183 LQAMTR-GVGISHYLAAG------NSSDVDVADFIATLADDPEVGSIICLFEGVKSGARF 235

Query: 270 KIVNAMK-ATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRN 323
                +  A GKP V    G T A  +       + +   A     L  V A + 
Sbjct: 236 LEAARLADAAGKPLVVYKAGNTAASGKAALSHTGTLVGSVAAYRAALEEVGAIQT 290


>UniRef50_A9A1Y1 CoA-binding domain protein n=6 Tax=Thaumarchaeota
           RepID=A9A1Y1_NITMS
          Length = 698

 Score = 55.8 bits (133), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 38/174 (21%), Positives = 68/174 (39%), Gaps = 13/174 (7%)

Query: 156 EIQLKTRAREKGLLVMGPDCGTSMIAGTPL----AFANVMPE-GNIGVIGASGTGIQELC 210
           E Q+   A++  + V+GP+C   M   +       F  V P+ G I ++  SG     L 
Sbjct: 111 EQQVIDIAKKYNMQVVGPNCLGVMNLDSKTMMNSTFLKVTPKSGKIALVSQSGAICAALV 170

Query: 211 SQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSK--PPAEAVR 268
              +  G G +  + LG + +  EV        L++L+  +++EV+    +     +   
Sbjct: 171 EDASAQGIGFSAVVSLGNKAVMSEV------DVLKILANHKQTEVIVMYLEDMGDGQEFL 224

Query: 269 LKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARR 322
               N  K   KP + L  G +P  A+       + +        LL +  A R
Sbjct: 225 KVCKNITKKLKKPVLVLKSGRSPEGAKAAMSHTGALMGSDEIYDALLKQSGAIR 278


>UniRef50_C1DBF7 Probable acetyl-CoA synthetase n=1 Tax=Laribacter hongkongensis
           HLHK9 RepID=C1DBF7_LARHH
          Length = 897

 Score = 55.8 bits (133), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 35/207 (16%), Positives = 72/207 (34%), Gaps = 15/207 (7%)

Query: 98  SSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFS----DNVTL 153
           + + +  +    S        +LA+++ A      +  +   + +  ++F+    D   L
Sbjct: 50  NHRVVGGMPAVSSVRSIEAPIDLAVVTTAVRTWPGIMKECGKKGVKAVLFAKEFGDADPL 109

Query: 154 EDEI--QLKTRAREKGLLVMGPDCGTSMIAGTPLAFAN---VMPEGNIGVIGASGTGIQE 208
             E+  +    ARE  + V+GP+    M     L  +N    +  GN+ ++  S      
Sbjct: 110 AHEVMQESLAIAREYRIRVLGPNMLGLMRPTIGLNASNYNGTVRAGNLALVSHSSALCAA 169

Query: 209 LCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVR 268
           +       G G T  I +G      +   +     L+ L  D +++ +        +A R
Sbjct: 170 MLDWADAKGIGFTSVISMG------DSVDLDFGEILDYLVYDNQTQGILLHLHHIHDARR 223

Query: 269 LKIVNAMKATGKPTVALFLGYTPAVAR 295
                 M +  KP V +  G       
Sbjct: 224 FMSALRMASRTKPVVVIKSGRAAEPLS 250


>UniRef50_A8ZY45 CoA-binding domain protein n=4 Tax=Desulfobacteraceae
           RepID=A8ZY45_DESOH
          Length = 753

 Score = 55.4 bits (132), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 37/219 (16%), Positives = 75/219 (34%), Gaps = 16/219 (7%)

Query: 100 QALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNL-NVMMFSDNV--TLED- 155
           + +   + + +      D +LA++++      +L      + + ++++ S     T E+ 
Sbjct: 316 ETIAGRKTYPTVSAIPGDVDLAVVTIPAAKVLDLIPDLETKGVKHMLLISSGFGETGEEG 375

Query: 156 ---EIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVM---PEGNIGVIGASGTGIQEL 209
              E ++  RAR   +L++GP+          L           G I ++  SG    +L
Sbjct: 376 KKLEARVVERARAADILMVGPNTMGIANPHIKLYCTGTHVWPDPGGIAMVSQSGNMGGQL 435

Query: 210 CSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRL 269
                  G  I    G G   +      ++    L     DE SE++    +   +  R 
Sbjct: 436 LQFAEQQGIEIRAFSGSGNEAM------VTIEDYLHAFEVDELSEIVMLYIESVKDGRRF 489

Query: 270 KIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEA 308
                  +  KP V L  G T    +       +   +A
Sbjct: 490 LEYARRLSMKKPIVLLKGGQTKVGEKAAASHTGAMASDA 528


>UniRef50_B2GFB1 Putative uncharacterized protein n=1 Tax=Lactobacillus fermentum
          IFO 3956 RepID=B2GFB1_LACF3
          Length = 60

 Score = 55.4 bits (132), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 17/42 (40%), Positives = 24/42 (57%)

Query: 18 MIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNA 59
          M+++  L E   V++V VMMGTPANK +  T G      + A
Sbjct: 1  MLLTNHLKEIAGVNNVQVMMGTPANKDIFKTGGLATPKLDEA 42


>UniRef50_A3TZP8 Putative acetyl-CoA synthetase n=1 Tax=Oceanicola batsensis
           HTCC2597 RepID=A3TZP8_9RHOB
          Length = 463

 Score = 55.4 bits (132), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 36/240 (15%), Positives = 86/240 (35%), Gaps = 19/240 (7%)

Query: 113 QKLPDANLALISVAGEYAAELANQALDRNLNVMM-----FSD--NVTLEDEIQLKTRARE 165
           +     ++ +++     A +        N+ V++     FS+  +   E+E +L+   ++
Sbjct: 71  EIDGPIDVVVLATPVGAALDALETCTRLNVKVVVGVTSGFSEAGDDGHENEERLRKIMQD 130

Query: 166 KGLLVMGPDCGTSMIAGTPLAFA-----NVMPEGNIGVIGASGTGIQELCSQIALAGEGI 220
               ++GP+C   +   + L        N +  G + +I  SG     +  ++   G GI
Sbjct: 131 APFRLVGPNCEGVVRPASDLQLTFSPMFNGLRPGPVAMISQSGALAGLMALRLGERGVGI 190

Query: 221 THAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVR-LKIVNAMKATG 279
              +  G          ++A   L+    D ++ V+    +   +  R  +    +   G
Sbjct: 191 NAIVSSGNE------TDLTAAHLLDYFGNDPQTRVVLCYVEELRDGRRFAEAAQRLTRAG 244

Query: 280 KPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTG 339
           K  VA+  G + A +R       +   +   ++ +       R   +  +   +  L  G
Sbjct: 245 KHVVAVKGGRSRAGSRAVQSHTGAMAGDDRVISAVFRETGVIRARESVAAVDAVTALAAG 304


>UniRef50_C4XLT1 CoA-binding domain protein n=1 Tax=Desulfovibrio magneticus RS-1
           RepID=C4XLT1_DESMR
          Length = 899

 Score = 55.4 bits (132), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 44/244 (18%), Positives = 79/244 (32%), Gaps = 25/244 (10%)

Query: 158 QLKTRAREKGLLVMGPDCGTSMIAGTPL--AFANV-MPEGNIGVIGASGTGIQELCSQIA 214
           ++   A   G+ ++GP     ++ G  L  + AN     G +  I  S +    +     
Sbjct: 118 RMIEAAAPSGIRILGPSGMGLLVPGIGLNCSLANRDARPGRMAFISQSASLFTAVLDWAH 177

Query: 215 LAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNA 274
             G G +H + LG R        +     L+ +++D  +  +    +   +A      + 
Sbjct: 178 TKGVGFSHILSLGDR------VDLKYADILDYMASDPNTRSILLYVESVTDARSFMSASR 231

Query: 275 MKATGKPTVALFLGYTPAVARDENVWFASS--LDEAARLACLLSRVTARR--------NA 324
             A  KP + +  G                   DEA R A +L                 
Sbjct: 232 AAARNKPLLVVKPGRKLWTLFPPGPDEGRDEVYDEAFRRAGMLRVGEIDTLFDAAETLAR 291

Query: 325 IAPVSSGFICGLYTGGTLAAEAAGLLAGH------LGVEADDTHQHGMMLDADSHQIIDL 378
             P+S   +  L  GG++   AA  L            EAD      +  +     ++D+
Sbjct: 292 ARPLSGDHLSILTNGGSVGVMAADALLDGGGRLAPFDAEADAALSPLLGPNWSRKGVVDM 351

Query: 379 GDDF 382
           G D 
Sbjct: 352 GVDA 355


>UniRef50_A8KXI0 CoA-binding domain protein n=3 Tax=Frankia RepID=A8KXI0_FRASN
          Length = 977

 Score = 55.4 bits (132), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 60/375 (16%), Positives = 125/375 (33%), Gaps = 50/375 (13%)

Query: 112 CQKLPDA-NLALISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEI--QLKTRA 163
            +++PDA +LA+I+V     A+      ++++  ++     F++          ++   A
Sbjct: 336 VREIPDAVDLAVIAVPAPAVADAVRACAEKDIRGLIVVSAGFAEAGPDGRARLAEVTRLA 395

Query: 164 REKGLLVMGPDCGTSMIAGTPLAF-----ANVMPEGNIGVIGASGTGIQELCSQIALAGE 218
           RE G+ ++GP+    +     +       A   P G +G    SG       ++ +    
Sbjct: 396 RESGMRLIGPNAMGVINTDPAVRLHATFAAGDPPVGRVGAFTQSGALAGTFLTEASRRAI 455

Query: 219 GITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKAT 278
           G++  +  G R        +SA   L+   +D  ++V+    +      +   +      
Sbjct: 456 GLSTFVSTGDR------SDVSANDVLQYWQSDPHTDVIMLHLQGFGNPRKFARIARRVGR 509

Query: 279 GKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYT 338
            KP +AL  G + A    + ++ ++ +     L+ L        +   P           
Sbjct: 510 RKPVIALKSGRSAADPALDALFTSAGVIRVDTLSQLFDLAALLASQPLPAGRRV------ 563

Query: 339 GGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHP-------- 390
            G +   +A                      A +  + D      T+GRP P        
Sbjct: 564 -GVVGTSSALAALATDACRTAGLEVPPFS-TATAEALSD------TLGRPEPANPVDLGA 615

Query: 391 MIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYA 450
           M  P  R +      A       +L ++        PA   V    +A  A   +  +  
Sbjct: 616 MAAPE-RFERALRAVAASADVDAVLALIT-----PHPA---VEELARAVRAVAGSGRVPV 666

Query: 451 IATVTGTERDPQCRS 465
           +A+  G +  P   +
Sbjct: 667 VASYLGYDGMPSALA 681


>UniRef50_Q1LCA0 CoA-binding n=2 Tax=cellular organisms RepID=Q1LCA0_RALME
          Length = 715

 Score = 55.1 bits (131), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 49/220 (22%), Positives = 82/220 (37%), Gaps = 27/220 (12%)

Query: 88  ALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVM-M 146
            +          QA   V    +A         A + V G   AE   Q+  R   V+ +
Sbjct: 61  PVNAGRSEVMGLQAYPSVAALPAAIDH------AFVMVPGAQVAEALEQSAARGARVVTV 114

Query: 147 FSDNVT------LEDEIQLKTRAREKGLLVMGPDC-GTSMIAGTPLAFANVMP------E 193
           FSD         +  +  L  RARE G+ ++GP+  G   +    +   N +        
Sbjct: 115 FSDGFAEVGEAGMAAQQALAARARELGVRLLGPNSIGVVDVHSGAVLSVNAVLEMDTLHR 174

Query: 194 GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKS 253
           G + VI  SG+ +  L S+ A  G G    + +G      ++G       +++L  D  +
Sbjct: 175 GPVSVISQSGSMLGALLSRGAARGLGFAKLVSVGNE---SDIG---VGELVDLLVDDAAT 228

Query: 254 EVLAFVSK-PPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
           EV+    +     AV    +   +A GKP +   LG +  
Sbjct: 229 EVILLFLETIRDAAVLGPALRRARAAGKPVLVYKLGRSEQ 268


>UniRef50_A3K489 CoA-binding protein n=1 Tax=Sagittula stellata E-37
           RepID=A3K489_9RHOB
          Length = 689

 Score = 55.1 bits (131), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 68/419 (16%), Positives = 133/419 (31%), Gaps = 72/419 (17%)

Query: 117 DANLALISVAGEYAAELANQALDRNL-NVMMFSDNVTLEDEI------QLKTRAREKGLL 169
             +L ++ V     A+    ++ R + +V++FS       E       +L    RE  + 
Sbjct: 61  GIDLLVLIVPKAAIADAIRDSIARKIGSVVVFSAGFAETGEEGRILQEELAALCREADMP 120

Query: 170 VMGPDCGTSM--IAGTPLAFANVMPEG-----NIGVIGASGTGIQELCSQIALAGEGITH 222
           ++GP+C   +    G P+ F  + P        +G+I  SG     + + +      ++ 
Sbjct: 121 MLGPNCMGFINYKDGVPITFERMAPRALGTSKAVGIIAQSGATASNIRAAMHGRAIDVSC 180

Query: 223 AIGLGGRDLSREVGGISALTALEMLSADEKSEVL-AFVSKPPAEAVRLKIVNAMKATGKP 281
            +  G    +    G  A   +E +  D +  ++  +V +       L + +  +A G P
Sbjct: 181 VVATG----NEAQTG--AEDYIEAMLDDPQIGLIAVYVEQIRNGPRFLDVAHRARAKGVP 234

Query: 282 TV------------------ALFLGYTPAVA---RDENVWFASSLDEAARLACLLSRVTA 320
            V                      G   A+    R   V    + +E   ++ +L     
Sbjct: 235 IVMLHPGASDKGAEAALSHTGAMAGNHAAMRTAMRYAGVAIVETTEELFDVSAILLNWPT 294

Query: 321 RRNAIAPV--SSGFICGL---YTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQI 375
                  V  +SG I GL   +       EA  L      +      +    +D ++   
Sbjct: 295 PVPGGVGVISNSGAIRGLSFDFC------EAIEL--PIAPLAQPTLDRLSAEIDGEASNP 346

Query: 376 IDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAW 435
           +D+G   +          P +       +   P V V+L             A +L    
Sbjct: 347 LDIGTTGFVR--------PEIFGTSTQAMLDDPAVGVVL-------NCHVGGAPNLQIVK 391

Query: 436 QKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH 494
                   D      + T+ G + DP   +  +  + D+GI    S   A      +  
Sbjct: 392 SDHLLPVFDTAQKPVVLTILG-DEDPLDPAF-VKAVRDSGIPFFRSPERALRAIRVVQK 448


>UniRef50_Q1M4T1 Putative pimeloyl-CoA synthetase n=1 Tax=Rhizobium leguminosarum
           bv. viciae 3841 RepID=Q1M4T1_RHIL3
          Length = 701

 Score = 55.1 bits (131), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 42/226 (18%), Positives = 83/226 (36%), Gaps = 28/226 (12%)

Query: 88  ALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN--VM 145
            +   A+     +A   +R  D+A       ++A+I +A +       +A    +   V+
Sbjct: 49  PVHPKAEAVFGYRAAPSLRALDAA------PDVAVIGIAADKVIAALEEAGSTGVKAAVV 102

Query: 146 MFSDNVTLED-----EIQLKTRAREKGLLVMGPDCGTS--MIAGTPL---AFANVMPEGN 195
           + S    L++     + QL   A   G+ + GP+C     + +G  L   + +  + +G 
Sbjct: 103 LASGFAELDEAGRERQRQLVEIAGRYGMAICGPNCLGLFNLTSGAALYSSSLSANLQKGR 162

Query: 196 IGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEV 255
             ++  SG       +    A  G++H +  G                LE L++DE +  
Sbjct: 163 FAILSHSGA---SAIALGNTARFGLSHIVSSG------NSAATDIPAYLEFLASDEDTGT 213

Query: 256 L-AFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           +   +    A       +  M A  KP +AL  G +   A+     
Sbjct: 214 VGIVIEAIRAPEELAAAMEKMHAANKPVIALRAGRSSRGAQATAAH 259


>UniRef50_B6JHC2 N-acetyltransferase n=5 Tax=Rhizobiales RepID=B6JHC2_OLICO
          Length = 898

 Score = 55.1 bits (131), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 78/422 (18%), Positives = 145/422 (34%), Gaps = 65/422 (15%)

Query: 112 CQKLPDANLALISVAGEYAAELANQALDRNLNV-MMFSDNVTLEDEIQ--LKTRAREKGL 168
              +PD  L +I        +L  +  ++     ++ +  +T E+ ++  +   ++   L
Sbjct: 66  LPGIPD--LGVIITPAAVVPDLIKELGEKGTRAAVVITAGITRENGLRQAILDASKPHLL 123

Query: 169 LVMGPDCGTSMIAGTPL--AFANV-MPEGNIGVIGASGTGIQELCSQIALA---GEGITH 222
            ++GP+    ++    L  +FA++    GNI ++  SG       S I  A   G G + 
Sbjct: 124 RIIGPNTLGLVLPLAKLNASFAHMGAAPGNIALLSQSGAIA---TSLIDWAAANGIGFSQ 180

Query: 223 AIGLGGRDLSREVGGISALTALEMLSADEKSEVLAF-VSKPPAEAVRLKIVNAMKATGKP 281
            + LG      ++  +     L ML+ D ++  +   +   P    +        A  KP
Sbjct: 181 IVSLG------DMADVDVADCLNMLAGDAQTRAIVMYLESVPNPR-KFMTAARAAARVKP 233

Query: 282 TVALFLGYTPAVARDENVWFA------SSLDEAARLA--------CLLSRVTARRNAIAP 327
            +A+  G     A+               +D A R A          L   T      +P
Sbjct: 234 VIAIKPGRHAEAAKAAATHTGALSGVDRVVDAALRRAGILRVNELADLFGATETIARFSP 293

Query: 328 VSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDAD-----SHQ-IIDLGDD 381
           +    +  +  GG     A   L    G  A  + +    LD       SH   +D+  D
Sbjct: 294 IERARVGIVTNGGGAGVLAVDRLMDFHGELAVLSPKTIAALDQTLPSNWSHANPVDIVGD 353

Query: 382 FYTVGRPHPMIDPTLRNQLIADL-GAKPQVRVL-LLDVVIGFGATADPAASLVSAWQKAC 439
                       P  R +   +   A P V VL +++   G  +++D AA+ V++  K  
Sbjct: 354 A-----------PPERYRAAVEAVAADPDVDVLMVMNCPTGVASSSD-AATTVASLAKNG 401

Query: 440 AARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPA 499
                      +    G     Q        L+ AGI    +   AT  A + +   S +
Sbjct: 402 TINDK----PVLTCWLGE----QSARGARRLLQAAGITSYETPA-ATATAVSYLTDWSRS 452

Query: 500 AQ 501
            +
Sbjct: 453 QK 454


>UniRef50_A8I8X8 ATP citrate lyase, subunit B n=1 Tax=Chlamydomonas reinhardtii
           RepID=A8I8X8_CHLRE
          Length = 534

 Score = 55.1 bits (131), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 44/243 (18%), Positives = 88/243 (36%), Gaps = 31/243 (12%)

Query: 97  GSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALD-RNLNVM-MFSDNVTLE 154
            +  A+        A +K P A++ +   +   A E + QAL+   L V+ + ++ V  +
Sbjct: 58  KNEIAIPVYGSIAEATRKHPKADVFINYASFRSAYESSLQALNSATLRVIAIIAEGVPEK 117

Query: 155 DEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIA 214
           D   L   AR    +++GP    + + G        +  G   +   +GT    +  ++ 
Sbjct: 118 DTKHLIAVARANNKVIIGP----ATVGG--------VQAGAFKIGDTAGTLDNIVACKLH 165

Query: 215 LAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVN- 273
             G     ++G        + GG+S     EM +     +++  + +         +   
Sbjct: 166 RPG-----SVG-----FVSKSGGMSN----EMYNHIPAIKMIVVLGELGGADEYGLVEAI 211

Query: 274 AMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARL--ACLLSRVTARRNAIAPVSSG 331
              A  KP VA   G    + + E       L  A  L  A  +      ++  A V++G
Sbjct: 212 KAGAVTKPVVAWVSGTCAKLVKSEVQSVYDRLVAAGTLVPAADVPAPAVPQDLAAAVAAG 271

Query: 332 FIC 334
            + 
Sbjct: 272 KVR 274


>UniRef50_C5BNQ0 Long-chain-fatty-acid--CoA ligase n=1 Tax=Teredinibacter turnerae
           T7901 RepID=C5BNQ0_TERTT
          Length = 897

 Score = 54.7 bits (130), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 44/243 (18%), Positives = 83/243 (34%), Gaps = 29/243 (11%)

Query: 120 LALISVAGEYAAELANQALDRNLNV-MMFSDNVTLEDE------IQLKTRAREKGLLVMG 172
           LA+I+       ++  Q     +   ++F+      DE        L   AR+ G+  +G
Sbjct: 75  LAIITTPAHTVKDILKQCGKHKVKAAVIFAGGFAQPDEPGKVSEQALVEIARKYGIRFIG 134

Query: 173 PDCGTSMIAGTPL--AFA-NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
           P+        T +   F    +  GN+ ++  SG     +    A+   G +  + +G  
Sbjct: 135 PNSLGIAHPSTNINATFGPGEVASGNLALVSQSGAVCTAVMDWAAVQDIGFSSVVSIG-- 192

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
                   +     L+ L +D K+  +    +   +A          A  KP + +  G 
Sbjct: 193 ----ACADLDFGDILDFLVSDGKTRSILLYVEGIRDARSFMCGLRAVARVKPVIVIKAGR 248

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGL 349
             A         ++ + +    A  L R            +G + G++ G  LAA A  L
Sbjct: 249 HKAAIEVTQSHNSARVGDDDVFAAALKR------------AGVVRGMHLGDLLAA-ANIL 295

Query: 350 LAG 352
             G
Sbjct: 296 ARG 298


>UniRef50_Q0K4A4 Pimeloyl-CoA synthetase n=1 Tax=Ralstonia eutropha H16
           RepID=Q0K4A4_RALEH
          Length = 718

 Score = 54.7 bits (130), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 68/411 (16%), Positives = 125/411 (30%), Gaps = 37/411 (9%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQG---SGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   + D                        + S Q +  +R + S        + A+
Sbjct: 22  IAVVGASDDPTRINGRPIAFARRFGYEGAIYPINPSRQTVQGLRAYPSLRDAPDGIDCAI 81

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEI------QLKTRAREKGLLVMGPDC 175
           I++      +  +Q   + +  V++F+       E       ++   AR  G+ ++GP+ 
Sbjct: 82  IALPAALVIDALHQCAGKGIRAVVLFTSGFAELGEAGQRKQEEITRIARAHGIRLLGPNV 141

Query: 176 GTS--MIAGTPLAFA----NVMPEGN--IGVIGASGTGIQELCSQIALAGEGITHAIGLG 227
                +   T + F       +P G   IG++  SG     +       G  +   +  G
Sbjct: 142 IGCFCLSRKTYVTFLSDVDGALPAGKPRIGLVSQSGGYGAHIYKLALQRGLAVDQVVTTG 201

Query: 228 GRDLSREVGGISALTALEMLSADEKSEVLAF-VSKPPAEAVRLKIVNAMKATGKPTVALF 286
                     I     +E ++     +++   +    ++A  ++ + A     KP V + 
Sbjct: 202 NE------ADIELGEVMEWMAESPDVDIIVGYIEGIRSKASFIRGLEAAHRKRKPVVLMK 255

Query: 287 LGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEA 346
           +G T A A       A+     A    LL    A R          +  L  G  L    
Sbjct: 256 VGATQAGAAAAASHTAALAGADAVYDALLREYGAYRARSNEEVLDVVYALSAGKPLR--- 312

Query: 347 AGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRP----HPMIDPTLRNQLIA 402
                  LGV          + D  S   +DL        R      P   P     + A
Sbjct: 313 ----KRKLGVVTISGGAGVQIADFASEAGLDLPMPSEATQRALREIAPFGSPANPVDVTA 368

Query: 403 DLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIAT 453
            +   P++    LD ++  G        L  A   A A       +  IA 
Sbjct: 369 QISNDPEIFTATLDRLLDAG-YDSLLMWLGPAVTNARAGAPIRATIERIAA 418


>UniRef50_C2APW0 Acyl-CoA synthetase (NDP forming) n=1 Tax=Tsukamurella
           paurometabola DSM 20162 RepID=C2APW0_TSUPA
          Length = 727

 Score = 54.7 bits (130), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 97/492 (19%), Positives = 159/492 (32%), Gaps = 68/492 (13%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWD-----SACQKLPDANL 120
           +A+   + D   A+   Q +    +   +           R        S  +   D ++
Sbjct: 29  IAVVGASTD--PAKRGYQSIRALQRSGYRHPIHPVNPRATRILGLDVAPSVEELPRDIDV 86

Query: 121 ALISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGP 173
           ALI++ G    +         +   +        S +     E +L     E G+ V+GP
Sbjct: 87  ALIALPGPLVPDALRACAGVGIRSAVVLANGFKESGHAGAALEAELAAVIAETGIRVIGP 146

Query: 174 DCGTSMIAGTPLAFANV--MPEGNIGVIGASGTGIQELCSQIALA--GEGITHAIGLGGR 229
           +    + A T      +  +P+G I V+  SG  +  L      A  G G     GLG +
Sbjct: 147 NTSGIINASTGANLVGLLDIPQGPISVVTQSGNMLLSL-VNDDRALQGPGFHVYAGLGNQ 205

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
                   +S    L  ++ D+++  +A  ++   +     +  A      P V +  G 
Sbjct: 206 ------VDVSYADCLTAMAEDDQTGAIAVHAEGLIDGRGFLVAAARAVADTPVV-MVRGG 258

Query: 290 TPAVARDENVWFASSL--DEAARLACLLSRVTARRNA-------------IAPVSSG-FI 333
              + R   +    S+   +A   A L        +                PV +G  I
Sbjct: 259 RSEIGRRTALSHTGSVAGSDAVATAVLRQAGVELVDRSDELAVVAGALAATVPVQAGRSI 318

Query: 334 CGLYTGG---TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHP 390
             L  GG   TLAA+A       LGV   +T       +   H++  L  D   V  P  
Sbjct: 319 AILADGGGHATLAADAL----AELGVSLANTS------EQTQHRLRQLLGDAAAVANPVD 368

Query: 391 M-----IDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLD- 444
           +      DPT+       L A P V ++L+  + G G      A L +A Q       D 
Sbjct: 369 VAGATDADPTVFVDAARILMADPAVGLVLIVGMFG-GYHLRFDAGLHAAEQSTADRLADL 427

Query: 445 --NQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQ 502
                +  +         P       A L   G  VV+S+  A  + AAL          
Sbjct: 428 SRAARIPLVVQSCYAAA-PNPVH---ARLRTEGFTVVNSIDHAARIVAALTRRGDRLGTA 483

Query: 503 HTPSLLENVAVI 514
              S L     I
Sbjct: 484 GLRSDLALPTPI 495


>UniRef50_C5T5T1 CoA-binding domain protein n=1 Tax=Acidovorax delafieldii 2AN
           RepID=C5T5T1_ACIDE
          Length = 713

 Score = 54.7 bits (130), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 40/230 (17%), Positives = 83/230 (36%), Gaps = 26/230 (11%)

Query: 112 CQKLPDA-NLALISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRA 163
            + LP A +LA++++A E    +  +   R +   +        + +  +E + +L+  A
Sbjct: 62  VEALPQAPDLAVLAIAAEDVTSMLERCHARGIRAAIVYAAGFAEAGSAGVELQARLEQFA 121

Query: 164 REKGLLVMGPDC-GTSMIAGTPL-AFANVMPE-------GNIGVIGASGTGIQELCSQIA 214
           +  G+++ GP+C G + I      AFA V          G   +I  SG     + + I 
Sbjct: 122 QRTGMVIAGPNCMGFANINTHAYTAFAAVFKNVPVQTQCGRASIITQSGNVCSAVFALIR 181

Query: 215 LAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKP--PAEAVRLKIV 272
             G  ++H I  G   +            LE ++ D+ +E +    +            +
Sbjct: 182 KLGIPVSHFINTGNEAVVE------FSEYLEYMAQDDATECVIGYVEQLRNGPRFIHAAL 235

Query: 273 NAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARR 322
                  KP +    G T   +       ++   + A      +++   R
Sbjct: 236 ALAAQ-KKPLIIYKAGETDKGSEAVRSHTSALAGDLALYKAGFAQLNVIR 284


>UniRef50_Q0RF38 Putative uncharacterized protein n=1 Tax=Frankia alni ACN14a
           RepID=Q0RF38_FRAAA
          Length = 706

 Score = 54.3 bits (129), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 49/270 (18%), Positives = 87/270 (32%), Gaps = 41/270 (15%)

Query: 87  EALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMM 146
             +      +     +  +R          DA  +L+  AG          L     V++
Sbjct: 17  HLVSPRPGVAYGRSTVASLRAVGGPV----DAVFSLVGAAGSVGVVEEAAQLGCGGVVVV 72

Query: 147 FSDNVTLEDEIQLKTRAREKGLL-----VMGPDCGTSM--IAGTPL--AFANVMPEGNIG 197
            S      DE + +     +        V GP+C   +   +G  L    A  +P G + 
Sbjct: 73  ASGFAEAGDEGRERQDRLARAAAGAALPVCGPNCTGLVNVTSGVSLFTGTAVAVPAGGVS 132

Query: 198 VIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVL- 256
           ++ +SG  ++   +       G+  A+  G   ++           L+ L AD  + V+ 
Sbjct: 133 LVSSSGYLMRAAMAAARERNLGLRLAVSAGNEAVT------VLADYLDFLVADPLTRVIT 186

Query: 257 AFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVA---------------------R 295
             + K    A     V   +A GKP V L LG +                         R
Sbjct: 187 VVIEKLRDPASFFAAVERARAAGKPVVVLKLGRSERARAIVRSHTGALTGESWVYDLAFR 246

Query: 296 DENVWFASSLDEAARLACLLSRVTARRNAI 325
              V  A  +D+    A +L+++ A R   
Sbjct: 247 AAGVVDARDVDDLMDRAAILAQLPAHRLRP 276


>UniRef50_Q7WE41 Putative acetyl-CoA synthetase n=2 Tax=Bordetella
           RepID=Q7WE41_BORBR
          Length = 713

 Score = 54.3 bits (129), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 45/264 (17%), Positives = 91/264 (34%), Gaps = 29/264 (10%)

Query: 111 ACQKLPDANLALISVAGEYAAELANQALDRNLNVMMF---------SDNVTLEDEIQLKT 161
           +   L   ++A++++  +   +   +     +   +           + V  +D  ++  
Sbjct: 74  SIAHLGPVDVAILALPVDMIEQAIGECAAAGVGACVIVSAGFAELGDEGVARQD--RIVR 131

Query: 162 RAREKGLLVMGPDCGTSMIAGTPLAFA-------NVMPEGNIGVIGASGTGIQELCSQIA 214
            ARE G+ ++GP+C   +     +A           +  GNIG+I  SG  +  +  +  
Sbjct: 132 IAREAGMRLVGPNCMGIINPHHRMALTSSLVVEQGELLPGNIGLISQSGALMVSMYDRAC 191

Query: 215 LAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVN- 273
                 +  + LG +        +      E +  D  + V+    +   +  R   +  
Sbjct: 192 REQIRFSACVSLGNQ------CDLEICDFFEYMIDDPLTRVITMYVEGFVDTGRFAELAR 245

Query: 274 AMKATGKPTVALFLGYTPAVARDENVWFASSLD--EAARLACLLSRVTARRNAIAPVSSG 331
             +  GKP +    G T A A       AS      A    C  + VT   +    +   
Sbjct: 246 RAQRAGKPVLLTKTGRTAAGAEAARSHTASLAGNYRALEALCEATGVTIVDDPDGMLQLA 305

Query: 332 FICGLYTGGTLAAEAAGLLAGHLG 355
            I   +  G  AAE  G+++   G
Sbjct: 306 AILARF--GRCAAEGVGIVSPSGG 327


>UniRef50_Q6FBA3 Pimeloyl-CoA synthetase n=2 Tax=Proteobacteria RepID=Q6FBA3_ACIAD
          Length = 701

 Score = 54.3 bits (129), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 34/229 (14%), Positives = 78/229 (34%), Gaps = 25/229 (10%)

Query: 118 ANLALISVAGEYAAELANQALDRNLN-VMMFS--------DNVTLEDEIQLKTRAREKGL 168
           A++AL++V      +   +   + +   ++FS        D   ++ E+     A+E  L
Sbjct: 70  ADVALLAVPASATVQAVRECAQKGIQTAIVFSAGFAEAGEDGHQMQQEM--LNAAKESNL 127

Query: 169 LVMGPDCGTSMIAGTPL--AFANV-----MPEGNIGVIGASGTGIQELCSQIALAGEGIT 221
            ++GP+C     A       F+ V     +  G + ++  SG     +       G GI 
Sbjct: 128 RLLGPNCLGVFNAYKKFYGTFSTVLDGDFIEPGAVSIVSQSGAYGSHIAHLCRQRGLGIG 187

Query: 222 HAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSK-PPAEAVRLKIVNAMKATGK 280
           + +  G          I    AL  +    + +V+   ++        ++ +   +    
Sbjct: 188 YWVTTGNE------CDIDLSDALNWVVDQPEVKVVLAYAEGIRHRDRFIQALEKAQRNNV 241

Query: 281 PTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVS 329
             + + +G +   A+  +   A+     A    +L +    R       
Sbjct: 242 AIIFMKVGRSEVGAKAASSHTAALAGSNAVFDAVLRQYGVIRAKTTTEQ 290


>UniRef50_Q7WM17 Putative uncharacterized protein n=1 Tax=Bordetella bronchiseptica
           RepID=Q7WM17_BORBR
          Length = 498

 Score = 54.3 bits (129), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 35/158 (22%), Positives = 60/158 (37%), Gaps = 8/158 (5%)

Query: 159 LKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPE--GNIGVIGASGTGIQELCSQIALA 216
           L   AR+  + V+GP+C         ++F   + +  G++GV+  SG    ++  +    
Sbjct: 117 LLAAARDANVRVVGPNCLGVYSPRARVSFTRRVTDEAGHVGVVCQSGGLGTDIIRRGQQR 176

Query: 217 GEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMK 276
           G   +  + +G          +SA   LE   ADE++ V+    +   +  RL  V    
Sbjct: 177 GLRFSGLVTIG------NAVDVSASELLEYFLADEQTRVIGMYLESARDGRRLFEVLRQA 230

Query: 277 ATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACL 314
              KP V L  G T    R  +    +        A L
Sbjct: 231 GCRKPVVLLKGGGTAQGRRAASSHTGALAGSEQAWAAL 268


>UniRef50_Q2LV26 Acetyl-CoA synthetase n=1 Tax=Syntrophus aciditrophicus SB
           RepID=Q2LV26_SYNAS
          Length = 482

 Score = 54.3 bits (129), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 40/273 (14%), Positives = 91/273 (33%), Gaps = 21/273 (7%)

Query: 42  NKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQA 101
           NK  +             +P+ + V   S + D      +   +     ++   +     
Sbjct: 11  NKEEIKHM-MTQKLVKLFSPDSVAVIGASNSFDKLGYHVMKSLVGHYAGKIYPINLKGGK 69

Query: 102 LTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN--VMMFSDNVTLED---- 155
           +  +  + S  +   + +LA+I V      E  +Q   + +   V++ +    +ED    
Sbjct: 70  VWNLDSYASLAEVPGNIDLAIIVVPAALVPETLHQCGGKGVKGAVLITAGFREIEDSQGG 129

Query: 156 --EIQLKTRAREKGLLVMGPDCGT--SMIAGTPLAFANVM---PEGNIGVIGASGTGIQE 208
             + +++    +  + ++GP+     ++  G   +F +      +G + +I  SG     
Sbjct: 130 VLQERIRKICDQYEMPIIGPNTSGFANIAFGIDASFTSEFCELEKGGVAIISQSGGLCHL 189

Query: 209 LCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEML-SADEKSEVLAFVSKPPAEAV 267
                     G++  + LG R        +    A+      DE ++V+A   +   E  
Sbjct: 190 CGFLALHQRMGVSSLMSLGNR------LNVGFPEAVRFFIEEDEATKVIALYIEGLDEPR 243

Query: 268 RLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
            L  +       KP VA   G +          
Sbjct: 244 ELLDMARSLRGKKPIVAYKSGKSAKSDSASKFH 276


>UniRef50_A3TKE9 Putative uncharacterized protein n=1 Tax=Janibacter sp. HTCC2649
           RepID=A3TKE9_9MICO
          Length = 892

 Score = 54.3 bits (129), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 35/240 (14%), Positives = 88/240 (36%), Gaps = 20/240 (8%)

Query: 96  SGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLED 155
           + +++ +   + +D+        +LA+I+V  +   ++ ++    +++ ++       E 
Sbjct: 243 NRNAKKILGRKTYDTIGDVPGPVDLAVIAVPADKVLKVVDECAAADVDALLIVSAGFGEG 302

Query: 156 --------EIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVM-----PEGNIGVIGAS 202
                   + +L  RAR  G+ ++GP+    +     L+    +     P+G++G+   S
Sbjct: 303 GGEGGDELQSELVRRARGSGMRIVGPNSFGLINTDPALSLNASLSPDMPPKGHLGLFAQS 362

Query: 203 GTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKP 262
           G     + +  A    GI+ + G  G  +  +V G   +        D+ +  +    + 
Sbjct: 363 GALGIAVLASAARRNLGIS-SFGSAGNRV--DVSGNDFMQ---YWIDDDDTHAVGLYLES 416

Query: 263 PAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARR 322
                +   +       KP + +  G + A           +    A  A +L +    R
Sbjct: 417 MGNPRKFSRIARNLGRIKPVIVVQSGVS-AYGAPPGHRVRRTKVRPAVFAAMLRQAGCIR 475


>UniRef50_Q12WB1 Acetyl-CoA synthetase (ADP-forming), alpha and beta subunits n=5
           Tax=Euryarchaeota RepID=Q12WB1_METBU
          Length = 696

 Score = 54.3 bits (129), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 35/184 (19%), Positives = 64/184 (34%), Gaps = 11/184 (5%)

Query: 156 EIQLKTRAREKGLLVMGPDCGTSM--IAGTPLAFANVM-PEGNIGVIGASGTGIQELCSQ 212
           E +     +E G+ ++GP+C   +   +G   +FA  M  +GNI ++  SG         
Sbjct: 110 ERRCAEIVKEHGMRMVGPNCLGIIDTASGLNASFAASMAKKGNISMMSQSGAICTSTLDW 169

Query: 213 IALAGEGITHAIGLGGR-DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKI 271
               G G +  I LG + DLS           L  +  DE + V+A   +   +  +   
Sbjct: 170 ADARGVGFSKFISLGNKADLSEN-------DFLLEMEDDENTAVIAAYLEGVKDGPKFME 222

Query: 272 VNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSG 331
           +    +  KP + +  G T   +R  +    +            S+    R         
Sbjct: 223 IARKVSRKKPIIVIKSGRTAVGSRAVSSHTGTLAGSDEAYNAAFSQSNVIRADSVEQLMD 282

Query: 332 FICG 335
            +  
Sbjct: 283 LMRA 286


>UniRef50_A3TZG5 Putative pimeloyl-CoA synthetase n=1 Tax=Oceanicola batsensis
           HTCC2597 RepID=A3TZG5_9RHOB
          Length = 715

 Score = 53.9 bits (128), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 45/271 (16%), Positives = 87/271 (32%), Gaps = 33/271 (12%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDS-------ACQKLPDA 118
           +A+   + D    +    ++  AL   +                        A    P  
Sbjct: 30  IAVVGASDD---LRKPGGRVVNALLHNSFPGKVYPVNPGRETIQGLECHPSLAAIAEP-V 85

Query: 119 NLALISVAGEYAAELANQALDRNLNVMM-----FSDNVT--LEDEIQLKTRAREKGLLVM 171
           +L ++SV  +          D  +   +     FS+     +  + ++    ++ G+ ++
Sbjct: 86  DLVILSVPADDVPNQLRMGCDCGVGGFIVFASGFSEIGPEGVARQAEISKIVQDAGIPMI 145

Query: 172 GPDCGTSMIAGTP-LAFANVM------PEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           GP+C   M      LA + V+      P GN G I  SG            AG G++  I
Sbjct: 146 GPNCLGIMNGNHKMLASSTVVMGGRKLPGGNYGFISQSGALGTYWLDMSMKAGLGVSSWI 205

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVL-AFVSKPPAEAVRLKIVNAMKATGKPTV 283
             G          +     L+ L  D+++EV+  ++      A             KP +
Sbjct: 206 STGNE------ADVDLAACLDYLVEDDETEVIGLYIEGVRDGAAFRAAARKAFERRKPVL 259

Query: 284 ALFLGYTPAVARDENVWFAS-SLDEAARLAC 313
            L  G +   A        + + ++ A  A 
Sbjct: 260 VLKSGSSRQGATAAASHTGALAGEDEAYDAV 290


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_D1AQ78 FdrA family protein n=1 Tax=Sebaldella termitidi...   511   e-143
UniRef50_Q47208 Protein fdrA n=96 Tax=Proteobacteria RepID=FDRA_...   508   e-142
UniRef50_C0WN22 Membrane protein n=1 Tax=Lactobacillus buchneri ...   472   e-131
UniRef50_A6TL44 FdrA family protein n=3 Tax=Clostridiales RepID=...   461   e-128
UniRef50_C5BXU8 FdrA family protein n=1 Tax=Beutenbergia caverna...   459   e-127
UniRef50_UPI000182709D FdrA family protein n=1 Tax=Enterobacter ...   427   e-118
UniRef50_P77187 Uncharacterized protein yahF n=55 Tax=Proteobact...   418   e-115
UniRef50_C0D6C1 Putative uncharacterized protein n=1 Tax=Clostri...   416   e-114
UniRef50_C2GZK2 Bacterial FdrA protein n=28 Tax=Bacteria RepID=C...   407   e-112
UniRef50_Q2RGM5 FdrA n=1 Tax=Moorella thermoacetica ATCC 39073 R...   404   e-111
UniRef50_A8VR79 Phage Terminase n=3 Tax=Firmicutes RepID=A8VR79_...   404   e-111
UniRef50_Q7BSA0 YahF/FdrA-like protein n=3 Tax=Proteobacteria Re...   392   e-107
UniRef50_B9KYM7 Protein fdrA n=1 Tax=Thermomicrobium roseum DSM ...   389   e-106
UniRef50_Q0TAN3 YahF/FdrA-like protein n=18 Tax=Gammaproteobacte...   389   e-106
UniRef50_B0VJR0 FdrA n=1 Tax=Candidatus Cloacamonas acidaminovor...   387   e-106
UniRef50_D1B8P5 FdrA family protein n=1 Tax=Thermanaerovibrio ac...   375   e-102
UniRef50_C1D754 YahF/FdrA-like protein n=1 Tax=Laribacter hongko...   360   6e-98
UniRef50_D0WIW7 Protein FdrA n=1 Tax=Slackia exigua ATCC 700122 ...   360   7e-98
UniRef50_D2L8W4 FdrA family protein n=1 Tax=Desulfovibrio sp. FW...   333   1e-89
UniRef50_UPI0001C165DF GCN5-related N-acetyltransferase n=2 Tax=...   327   7e-88
UniRef50_A6C207 Acetyl-CoA synthetase / acetyltransferase (GNAT)...   321   4e-86
UniRef50_B3DWI6 Acyl-CoA synthetase (ADP forming) alpha and beta...   317   5e-85
UniRef50_D2RGD1 Acetyl coenzyme A synthetase (ADP forming), alph...   314   7e-84
UniRef50_Q2JX06 Acetyltransferase, GNAT family n=25 Tax=Bacteria...   307   9e-82
UniRef50_D0MJL0 Acetyl coenzyme A synthetase (ADP forming), alph...   306   1e-81
UniRef50_B8CEH1 Acetyl-coa synthetase n=1 Tax=Thalassiosira pseu...   302   2e-80
UniRef50_D2R7V1 CoA-binding domain protein n=1 Tax=Pirellula sta...   300   8e-80
UniRef50_Q2LUQ3 Acetyl-CoA synthetase / acetyltransferase (GNAT)...   296   1e-78
UniRef50_D1A7Z1 FdrA family protein n=2 Tax=Actinomycetales RepI...   293   1e-77
UniRef50_A1SGR4 FdrA family protein n=1 Tax=Nocardioides sp. JS6...   290   1e-76
UniRef50_B5JNQ5 Acetyltransferase, GNAT family n=1 Tax=Verrucomi...   287   9e-76
UniRef50_Q2Y4P6 Probable acetyl-CoA synthetase n=1 Tax=unculture...   285   2e-75
UniRef50_B6AEK9 Acetyl-CoA synthetase, putative n=1 Tax=Cryptosp...   284   5e-75
UniRef50_Q47CI3 GCN5-related N-acetyltransferase:CoA-binding n=9...   283   2e-74
UniRef50_Q9NAT4 Acetyl-CoA synthetase n=3 Tax=Entamoeba RepID=Q9...   276   2e-72
UniRef50_Q58010 Uncharacterized protein MJ0590 n=11 Tax=Methanoc...   276   2e-72
UniRef50_Q3SEU0 Long-chain fatty-acid-CoA ligase n=4 Tax=Proteob...   274   5e-72
UniRef50_D2S3V1 FdrA family protein n=8 Tax=Bacteria RepID=D2S3V...   270   1e-70
UniRef50_C5A641 Acetyl-CoA synthetase (ADP forming), alpha chain...   270   1e-70
UniRef50_Q2Y8E7 GCN5-related N-acetyltransferase n=2 Tax=Betapro...   269   2e-70
UniRef50_B6YXJ0 Acetyl-CoA synthetase II (NDP forming), alpha su...   268   3e-70
UniRef50_D0L1W1 CoA-binding domain protein n=1 Tax=Halothiobacil...   267   1e-69
UniRef50_C9R913 Acetyl coenzyme A synthetase (ADP forming), alph...   266   2e-69
UniRef50_Q47QC9 Probable 6-carboxyhexanoate--COA ligase n=1 Tax=...   266   2e-69
UniRef50_C5A4T1 Acetyl-CoA synthetase (ADP forming), alpha chain...   265   3e-69
UniRef50_A4YGK5 CoA-binding domain protein n=15 Tax=Archaea RepI...   265   4e-69
UniRef50_D2LIT8 CoA-binding domain protein n=1 Tax=Rhodomicrobiu...   265   5e-69
UniRef50_Q8TVZ2 Acyl-CoA synthetase (NDP forming) n=1 Tax=Methan...   263   1e-68
UniRef50_A3DLQ0 Acetyl-CoA synthetase (ADP-forming) alpha subuni...   263   1e-68
UniRef50_B6YUH0 Archaeal succinyl-CoA synthetase (NDP forming), ...   261   4e-68
UniRef50_A4J695 CoA-binding domain protein n=6 Tax=Peptococcacea...   261   4e-68
UniRef50_Q1N4R6 Acyl-CoA synthetase (NDP forming) n=1 Tax=Berman...   261   6e-68
UniRef50_B8FK52 Acetyl coenzyme A synthetase (ADP forming), alph...   260   1e-67
UniRef50_A1U3K8 GCN5-related N-acetyltransferase n=4 Tax=Gammapr...   259   2e-67
UniRef50_Q12WB1 Acetyl-CoA synthetase (ADP-forming), alpha and b...   258   3e-67
UniRef50_C6C1C2 CoA-binding domain protein n=4 Tax=Desulfovibrio...   258   4e-67
UniRef50_B5YGJ9 Acetyl-CoA synthetase n=1 Tax=Thermodesulfovibri...   258   4e-67
UniRef50_C7MVA0 Acyl-CoA synthetase (NDP forming) n=1 Tax=Saccha...   258   6e-67
UniRef50_C0GR98 GCN5-related N-acetyltransferase n=1 Tax=Desulfo...   258   6e-67
UniRef50_B6YUE1 Acyl-CoA synthetase (NDP forming), large subunit...   255   3e-66
UniRef50_UPI0001B56A88 CoA-binding domain protein n=1 Tax=Strept...   255   3e-66
UniRef50_C5BNQ0 Long-chain-fatty-acid--CoA ligase n=1 Tax=Teredi...   255   3e-66
UniRef50_C5A3W6 Acetyl-CoA synthetase (ADP forming), alpha chain...   255   4e-66
UniRef50_Q9UYT1 AcdA-4 acetate--coA ligase (ADP-forming), alpha ...   253   1e-65
UniRef50_A0LL44 CoA-binding domain protein n=2 Tax=cellular orga...   253   2e-65
UniRef50_Q2RTE1 N-acetyltransferase n=13 Tax=Proteobacteria RepI...   251   5e-65
UniRef50_Q3IFA9 Putative acyl-CoA synthetase, NAD(P)-binding, AT...   250   1e-64
UniRef50_Q0W3R5 Acetyl-coa synthetase (ADP-forming), alpha subun...   250   1e-64
UniRef50_Q2RLH5 CoA-binding n=1 Tax=Moorella thermoacetica ATCC ...   249   2e-64
UniRef50_Q979A5 Succinyl CoA synthetase alpha subunit n=2 Tax=Th...   249   2e-64
UniRef50_C0QHB0 SucD4 n=1 Tax=Desulfobacterium autotrophicum HRM...   249   2e-64
UniRef50_Q64CM7 Putative uncharacterized protein n=1 Tax=uncultu...   247   8e-64
UniRef50_C0QAQ8 SucC4 n=1 Tax=Desulfobacterium autotrophicum HRM...   246   2e-63
UniRef50_C5U6W7 CoA-binding domain protein n=1 Tax=Methanocaldoc...   246   2e-63
UniRef50_B1L7G3 Acyl-CoA synthetase (NDP forming) n=1 Tax=Candid...   245   3e-63
UniRef50_B5YGW4 Acetyl-CoA synthetase n=1 Tax=Thermodesulfovibri...   245   3e-63
UniRef50_Q2NFU6 Predicted acyl-CoA synthetase n=4 Tax=Methanobac...   245   3e-63
UniRef50_B5IDQ5 CoA binding domain protein n=2 Tax=Aciduliprofun...   245   5e-63
UniRef50_B8D575 AcdA-1 acetate--coA ligase (ADP-forming), alpha ...   243   2e-62
UniRef50_Q30WE4 Acetyltransferase, GNAT family n=4 Tax=Desulfovi...   242   2e-62
UniRef50_C1DBF7 Probable acetyl-CoA synthetase n=1 Tax=Laribacte...   238   3e-61
UniRef50_Q3AFE8 Acetyl-CoA synthase n=1 Tax=Carboxydothermus hyd...   238   4e-61
UniRef50_A2SRS8 CoA-binding domain protein n=2 Tax=Methanomicrob...   237   7e-61
UniRef50_A8ZZJ4 CoA-binding domain protein n=2 Tax=Desulfobacter...   237   7e-61
UniRef50_C5A3H6 Acetyl-CoA synthetase (ADP forming), alpha chain...   237   9e-61
UniRef50_A3CY00 CoA-binding domain protein n=7 Tax=Methanomicrob...   236   1e-60
UniRef50_B8D4Z1 Acetyl-CoA synthetase n=1 Tax=Desulfurococcus ka...   236   2e-60
UniRef50_O28761 Putative uncharacterized protein n=1 Tax=Archaeo...   235   3e-60
UniRef50_C6C0V7 CoA-binding domain protein n=2 Tax=Desulfovibrio...   235   3e-60
UniRef50_Q2BN19 Acetyltransferase, GNAT family protein n=1 Tax=N...   233   1e-59
UniRef50_B9Z1Z5 GCN5-related N-acetyltransferase n=1 Tax=Lutiell...   233   1e-59
UniRef50_A1RX15 CoA-binding domain protein n=2 Tax=Archaea RepID...   233   2e-59
UniRef50_A2BLI1 Universally conserved protein n=1 Tax=Hypertherm...   232   2e-59
UniRef50_Q5P5S5 Predicted Acetyl-CoA synthetase n=2 Tax=Proteoba...   232   3e-59
UniRef50_B6JHC2 N-acetyltransferase n=5 Tax=Rhizobiales RepID=B6...   231   5e-59
UniRef50_A8BPG2 Acetyl-CoA synthetase n=4 Tax=Hexamitidae RepID=...   230   9e-59
UniRef50_C7LRJ9 CoA-binding domain protein n=1 Tax=Desulfomicrob...   230   1e-58
UniRef50_C4ZP63 CoA-binding domain protein n=1 Tax=Thauera sp. M...   230   2e-58
UniRef50_Q0S1K2 Possible acetyl-CoA synthetase n=10 Tax=Actinomy...   229   2e-58
UniRef50_B1T453 CoA-binding domain protein n=1 Tax=Burkholderia ...   229   2e-58
UniRef50_C0QHK1 SucC2 n=1 Tax=Desulfobacterium autotrophicum HRM...   229   2e-58
UniRef50_C7DI26 CoA-binding domain protein n=1 Tax=Candidatus Mi...   228   3e-58
UniRef50_B8FCT2 CoA-binding domain protein n=1 Tax=Desulfatibaci...   228   4e-58
UniRef50_C0D886 Putative uncharacterized protein n=1 Tax=Clostri...   227   7e-58
UniRef50_C7QE97 FdrA family protein n=1 Tax=Catenulispora acidip...   227   7e-58
UniRef50_C6E214 CoA-binding domain protein n=3 Tax=Geobacter Rep...   227   9e-58
UniRef50_C8S7L3 CoA-binding domain protein n=1 Tax=Ferroglobus p...   227   1e-57
UniRef50_O28341 Putative uncharacterized protein n=3 Tax=Archaeo...   227   1e-57
UniRef50_B8FN91 CoA-binding domain protein n=1 Tax=Desulfatibaci...   227   1e-57
UniRef50_A8ZSQ9 CoA-binding domain protein n=1 Tax=Desulfococcus...   226   1e-57
UniRef50_Q2LV26 Acetyl-CoA synthetase n=1 Tax=Syntrophus aciditr...   226   1e-57
UniRef50_B3PB71 Acetyltransferase, GNAT family n=1 Tax=Cellvibri...   226   2e-57
UniRef50_B3LBB6 Acetyl CoA synthetase, putative n=1 Tax=Plasmodi...   226   2e-57
UniRef50_B4RED1 Acetyl-CoA synthetase / acetyltransferase (GNAT)...   225   3e-57
UniRef50_C8QZV8 CoA-binding domain protein n=2 Tax=Desulfobulbac...   225   4e-57
UniRef50_A9A1Y1 CoA-binding domain protein n=6 Tax=Thaumarchaeot...   224   7e-57
UniRef50_D2B5B2 Acyl-CoA synthetase (NDP forming)-like protein n...   224   8e-57
UniRef50_C1XWJ3 Acyl-CoA synthetase (NDP forming) n=2 Tax=Meioth...   224   9e-57
UniRef50_A8MDR5 CoA-binding domain protein n=7 Tax=Thermoprotei ...   223   2e-56
UniRef50_Q2LS75 Acetyl-CoA synthetase beta subunit n=1 Tax=Syntr...   222   2e-56
UniRef50_A0LS83 CoA-binding domain protein n=1 Tax=Acidothermus ...   222   4e-56
UniRef50_B9R2H8 Acetyltransferase, GNAT family n=1 Tax=Labrenzia...   222   4e-56
UniRef50_B6R8H6 N-acetyltransferase n=1 Tax=Pseudovibrio sp. JE0...   221   5e-56
UniRef50_A2SEI4 Acyl-CoA synthetase (ADP forming) n=13 Tax=Burkh...   220   1e-55
UniRef50_Q2YZQ4 Acyl-CoA synthetase (NDP forming) n=1 Tax=uncult...   220   2e-55
UniRef50_D2EE92 CoA-binding domain protein n=2 Tax=Candidatus Pa...   218   3e-55
UniRef50_A8ZSN5 CoA-binding domain protein n=3 Tax=Desulfobacter...   218   6e-55
UniRef50_Q2LVF9 Acetyl-CoA synthetase beta subunit n=1 Tax=Syntr...   218   6e-55
UniRef50_C4XLT1 CoA-binding domain protein n=1 Tax=Desulfovibrio...   218   7e-55
UniRef50_D0LBS1 CoA-binding domain protein n=2 Tax=Corynebacteri...   217   8e-55
UniRef50_A1SKW5 CoA-binding domain protein n=3 Tax=Actinomycetal...   217   8e-55
UniRef50_C8WUT7 CoA-binding domain protein n=2 Tax=Alicyclobacil...   216   1e-54
UniRef50_C0QHU4 SucC3 n=1 Tax=Desulfobacterium autotrophicum HRM...   216   1e-54
UniRef50_D1ABG8 CoA-binding domain protein n=3 Tax=Streptosporan...   214   9e-54
UniRef50_Q6FBA3 Pimeloyl-CoA synthetase n=2 Tax=Proteobacteria R...   211   7e-53
UniRef50_Q02CE8 CoA-binding domain protein n=2 Tax=Bacteria RepI...   211   7e-53
UniRef50_Q2LRG1 Acyl-CoA synthetase n=8 Tax=cellular organisms R...   210   8e-53
UniRef50_D2L2A2 CoA-binding domain protein n=1 Tax=Desulfovibrio...   210   1e-52
UniRef50_A1WNK8 CoA-binding domain protein n=4 Tax=cellular orga...   210   1e-52
UniRef50_Q7MRU7 Putative uncharacterized protein n=1 Tax=Wolinel...   210   1e-52
UniRef50_Q8PZY1 Acetyl-CoA synthetase, alpha subunit n=4 Tax=Arc...   209   2e-52
UniRef50_A3TZP5 Acetyl-CoA synthetase n=1 Tax=Oceanicola batsens...   209   2e-52
UniRef50_D2LF69 GCN5-related N-acetyltransferase n=5 Tax=Alphapr...   208   4e-52
UniRef50_B8FGY7 CoA-binding domain protein n=1 Tax=Desulfatibaci...   208   4e-52
UniRef50_B2TEE7 CoA-binding domain protein n=1 Tax=Burkholderia ...   208   5e-52
UniRef50_Q1PVJ0 Similar to acetyl-CoA synthetase (ADP-forming) a...   208   5e-52
UniRef50_B8F999 CoA-binding domain protein n=1 Tax=Desulfatibaci...   207   8e-52
UniRef50_D1C154 CoA-binding domain protein n=1 Tax=Sphaerobacter...   207   9e-52
UniRef50_Q7WE41 Putative acetyl-CoA synthetase n=2 Tax=Bordetell...   206   2e-51
UniRef50_C5EFZ7 Putative uncharacterized protein n=1 Tax=Clostri...   206   3e-51
UniRef50_A5G5K1 CoA-binding domain protein n=2 Tax=Desulfuromona...   205   3e-51
UniRef50_A9ICA6 Acetyl-CoA synthetase n=1 Tax=Bordetella petrii ...   205   3e-51
UniRef50_B7X585 CoA-binding domain protein n=2 Tax=Comamonas tes...   204   5e-51
UniRef50_B2T9W3 GCN5-related N-acetyltransferase n=1 Tax=Burkhol...   204   1e-50
UniRef50_Q0S4P1 Probable acid--CoA ligase n=2 Tax=Rhodococcus Re...   204   1e-50
UniRef50_B0SVW7 CoA-binding domain protein n=2 Tax=cellular orga...   203   2e-50
UniRef50_Q3JJ59 Acetyltransferase, GNAT family n=65 Tax=Proteoba...   202   3e-50
UniRef50_A3TZP8 Putative acetyl-CoA synthetase n=1 Tax=Oceanicol...   202   3e-50
UniRef50_B8FE80 CoA-binding domain protein n=1 Tax=Desulfatibaci...   202   4e-50
UniRef50_Q47QC0 Putative uncharacterized protein n=2 Tax=Nocardi...   201   4e-50
UniRef50_A3TKE9 Putative uncharacterized protein n=1 Tax=Janibac...   201   4e-50
UniRef50_A7IQG8 CoA-binding domain protein n=1 Tax=Xanthobacter ...   201   8e-50
UniRef50_Q7WC02 Putative acyl-CoA synthetase n=2 Tax=Bordetella ...   200   1e-49
UniRef50_A3TZG5 Putative pimeloyl-CoA synthetase n=1 Tax=Oceanic...   198   5e-49
UniRef50_C2APW0 Acyl-CoA synthetase (NDP forming) n=1 Tax=Tsukam...   198   6e-49
UniRef50_Q7WM17 Putative uncharacterized protein n=1 Tax=Bordete...   198   6e-49
UniRef50_C8X6G7 GCN5-related N-acetyltransferase n=1 Tax=Nakamur...   198   7e-49
UniRef50_Q89PN4 Blr3446 protein n=1 Tax=Bradyrhizobium japonicum...   198   7e-49
UniRef50_Q46UX4 CoA-binding n=2 Tax=Cupriavidus RepID=Q46UX4_RALEJ    196   1e-48
UniRef50_A3DLS0 Succinyl-CoA synthetase (ADP-forming) alpha subu...   196   1e-48
UniRef50_UPI0000510214 CoA-binding domain protein n=1 Tax=Brevib...   196   1e-48
UniRef50_A0LG54 CoA-binding domain protein n=1 Tax=Syntrophobact...   196   2e-48
UniRef50_A1SC60 CoA-binding domain protein n=3 Tax=Nocardioides ...   196   3e-48
UniRef50_Q89GG9 Bll6376 protein n=1 Tax=Bradyrhizobium japonicum...   195   5e-48
UniRef50_C4ZKF4 CoA-binding domain protein n=1 Tax=Thauera sp. M...   194   6e-48
UniRef50_B8FIP4 CoA-binding domain protein n=1 Tax=Desulfatibaci...   194   8e-48
UniRef50_A8ZY45 CoA-binding domain protein n=4 Tax=Desulfobacter...   193   2e-47
UniRef50_D2PLU3 CoA-binding domain protein n=2 Tax=Actinomycetal...   193   2e-47
UniRef50_Q0K4A4 Pimeloyl-CoA synthetase n=1 Tax=Ralstonia eutrop...   192   3e-47
UniRef50_C0GIF8 CoA-binding domain protein n=1 Tax=Dethiobacter ...   190   9e-47
UniRef50_C5T5T1 CoA-binding domain protein n=1 Tax=Acidovorax de...   190   1e-46
UniRef50_Q46SD8 CoA-binding n=11 Tax=cellular organisms RepID=Q4...   190   1e-46
UniRef50_Q13HH2 Putative CoA ligase n=1 Tax=Burkholderia xenovor...   188   5e-46
UniRef50_UPI0001C30E25 CoA-binding domain protein n=1 Tax=Conexi...   188   5e-46
UniRef50_Q2LVD4 Acetyl-CoA synthetase beta subunit n=1 Tax=Syntr...   188   7e-46
UniRef50_Q2LPY1 Acetyl-CoA synthetase beta subunit n=1 Tax=Syntr...   188   7e-46
UniRef50_A4FCG4 Acyl-CoA synthetase (NDP forming type) n=2 Tax=A...   186   1e-45
UniRef50_Q0FX08 CoA-binding protein n=1 Tax=Roseovarius sp. HTCC...   186   2e-45
UniRef50_Q330N6 Acetyl-CoA synthetase (ADP-forming) alpha subuni...   186   2e-45
UniRef50_A0QZM0 CoA-binding protein n=3 Tax=Corynebacterineae Re...   186   3e-45
UniRef50_C7LZH4 GCN5-related N-acetyltransferase n=1 Tax=Acidimi...   185   3e-45
UniRef50_B9QZ08 CoA binding domain protein n=1 Tax=Labrenzia ale...   184   5e-45
UniRef50_A3K489 CoA-binding protein n=1 Tax=Sagittula stellata E...   184   5e-45
UniRef50_Q65SV2 Succinyl-CoA ligase [ADP-forming] subunit alpha ...   184   8e-45
UniRef50_A9ISQ2 Acetyl-CoA synthetase n=4 Tax=Burkholderiales Re...   183   1e-44
UniRef50_Q72GY5 6-carboxyhexanoate-CoA ligase n=3 Tax=Thermus Re...   183   2e-44
UniRef50_UPI00016B24F6 succinyl-CoA synthetase, alpha subunit n=...   182   3e-44
UniRef50_Q7VRY7 Acetyl-CoA synthetase n=3 Tax=Bordetella RepID=Q...   182   3e-44
UniRef50_C3XDZ9 Putative uncharacterized protein n=1 Tax=Helicob...   182   3e-44
UniRef50_B0UL28 CoA-binding domain protein n=36 Tax=Proteobacter...   182   4e-44
UniRef50_Q7WEC6 Putative pimeloyl-CoA synthetase n=1 Tax=Bordete...   181   8e-44
UniRef50_Q89Y14 Bll0141 protein n=1 Tax=Bradyrhizobium japonicum...   180   1e-43
UniRef50_Q46RU5 CoA-binding n=4 Tax=Betaproteobacteria RepID=Q46...   178   4e-43
UniRef50_B9L969 CoA binding domain protein n=2 Tax=Epsilonproteo...   177   8e-43
UniRef50_P53595 Malate--CoA ligase subunit alpha n=184 Tax=cellu...   177   1e-42
UniRef50_Q0K4B6 Acyl-CoA synthetase n=5 Tax=Burkholderiales RepI...   177   1e-42
UniRef50_Q7W1M6 Putative acetyl-CoA synthetase n=2 Tax=Bordetell...   177   1e-42
UniRef50_D1A3H7 CoA-binding domain protein n=3 Tax=Actinomycetal...   176   1e-42
UniRef50_Q3ADM2 Succinyl-CoA ligase [ADP-forming] subunit alpha ...   176   2e-42
UniRef50_Q13PC5 Putative acyl-CoA synthetase n=2 Tax=Burkholderi...   175   4e-42
UniRef50_A9ICC0 Putative acetyl-CoA synthetase n=1 Tax=Bordetell...   174   6e-42
UniRef50_C5D0J6 CoA-binding domain protein n=1 Tax=Variovorax pa...   174   9e-42
UniRef50_B9B8Y3 CoA binding domain protein n=1 Tax=Burkholderia ...   173   1e-41
UniRef50_B5I859 Succinyl-CoA ligase [ADP-forming] subunit alpha ...   173   2e-41
UniRef50_A8A9G7 CoA-binding domain protein n=1 Tax=Ignicoccus ho...   172   3e-41
UniRef50_A4WJJ0 CoA-binding domain protein n=3 Tax=Pyrobaculum R...   172   4e-41
UniRef50_A8KXI0 CoA-binding domain protein n=3 Tax=Frankia RepID...   171   5e-41

Sequences not found previously or not previously below threshold:

UniRef50_Q0HVJ0 CoA-binding domain protein n=113 Tax=Bacteria Re...   238   3e-61
UniRef50_P76594 Uncharacterized protein yfiQ n=154 Tax=Gammaprot...   234   8e-60
UniRef50_A1RXS7 CoA-binding domain protein n=5 Tax=Archaea RepID...   231   5e-59
UniRef50_Q1QWA2 CoA-binding n=1 Tax=Chromohalobacter salexigens ...   224   7e-57
UniRef50_C6BU19 CoA-binding domain protein n=3 Tax=Desulfovibrio...   223   1e-56
UniRef50_C9PHJ3 Protein acetyltransferase n=3 Tax=Gammaproteobac...   223   2e-56
UniRef50_A5V1W2 CoA-binding domain protein n=7 Tax=Bacteria RepI...   222   2e-56
UniRef50_A4EUN0 Predicted Acetyl-CoA synthetase n=2 Tax=Proteoba...   222   3e-56
UniRef50_C4ZN05 CoA-binding domain protein n=1 Tax=Thauera sp. M...   220   9e-56
UniRef50_B0UM89 CoA-binding domain protein n=19 Tax=Bacteria Rep...   220   1e-55
UniRef50_Q8IL89 Succinyl CoA ligase, putative n=5 Tax=Plasmodium...   215   3e-54
UniRef50_B2V3D0 CoA-binding domain protein n=6 Tax=Firmicutes Re...   209   2e-52
UniRef50_B0JLR7 Acetyl-CoA synthetase n=2 Tax=Microcystis aerugi...   209   3e-52
UniRef50_C0BX18 Putative uncharacterized protein n=1 Tax=Clostri...   209   3e-52
UniRef50_B8FEI4 CoA-binding domain protein n=2 Tax=Deltaproteoba...   206   2e-51
UniRef50_A7HF64 GCN5-related N-acetyltransferase n=1 Tax=Anaerom...   206   3e-51
UniRef50_A0KEL7 Acyl-CoA synthetase n=2 Tax=Aeromonas RepID=A0KE...   205   3e-51
UniRef50_B9LS76 CoA-binding domain protein n=9 Tax=Halobacteriac...   205   4e-51
UniRef50_D2RRG3 CoA-binding domain protein n=1 Tax=Haloterrigena...   204   5e-51
UniRef50_A6F7C2 Putative uncharacterized protein n=1 Tax=Moritel...   202   2e-50
UniRef50_A9A2G6 CoA-binding domain protein n=6 Tax=Thaumarchaeot...   200   1e-49
UniRef50_C9M5R5 CoA-binding protein n=1 Tax=Jonquetella anthropi...   199   2e-49
UniRef50_A0NUW5 Putative uncharacterized protein n=2 Tax=Alphapr...   192   3e-47
UniRef50_A4BCL0 Acyl-CoA synthetase (NDP forming) n=1 Tax=Reinek...   192   4e-47
UniRef50_D1B6J7 CoA-binding domain protein n=1 Tax=Thermanaerovi...   191   5e-47
UniRef50_Q0A9U7 GCN5-related N-acetyltransferase n=2 Tax=Ectothi...   184   6e-45
UniRef50_A1BC12 CoA-binding domain protein n=1 Tax=Paracoccus de...   183   1e-44
UniRef50_Q2KUZ0 Putative acetyltransferase n=5 Tax=Bordetella Re...   179   2e-43
UniRef50_B6JJ61 Acyl-CoA synthetase n=1 Tax=Oligotropha carboxid...   179   3e-43
UniRef50_B7UXS6 Pimeloyl-CoA synthetase n=13 Tax=cellular organi...   178   4e-43
UniRef50_Q46QN5 CoA-binding n=3 Tax=Burkholderiales RepID=Q46QN5...   177   1e-42
UniRef50_B2JRL3 CoA-binding domain protein n=1 Tax=Burkholderia ...   175   4e-42
UniRef50_B8X9X8 Pimeloyl-CoA synthetase n=1 Tax=Rhodococcus sp. ...   174   8e-42

>UniRef50_D1AQ78 FdrA family protein n=1 Tax=Sebaldella termitidis ATCC 33386
           RepID=D1AQ78_SEBTE
          Length = 573

 Score =  511 bits (1316), Expect = e-143,   Method: Composition-based stats.
 Identities = 249/578 (43%), Positives = 363/578 (62%), Gaps = 28/578 (4%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           M++  IKK  +QDSV+LM+++++LS +E ++ +SVMMGTPANK +   +G + ++  +AT
Sbjct: 1   MLYTIIKKNSYQDSVNLMLLTKELSAAEGIEKISVMMGTPANKEIFANSGLYTEELESAT 60

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           PNDIC+ I  +  D G    I++ +E  LK  +  S   + +   R WDSA +KLPDANL
Sbjct: 61  PNDICIVI--DTEDEGKIDGILESIESFLKNQSSKSK-GKKIPVARTWDSALRKLPDANL 117

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           A+IS+ GEYAAE  ++AL++ LNV +FSDNV++EDE ++K  AR KGLLVMGPDCGT +I
Sbjct: 118 AIISIPGEYAAEETSKALEKGLNVFLFSDNVSIEDEKRIKEEARTKGLLVMGPDCGTGII 177

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            G PLAFANV+ +GNIG++GASGTGIQE+ + I+  G GIT AIG GGRDLS ++  ++A
Sbjct: 178 GGLPLAFANVIEKGNIGIVGASGTGIQEISTIISRKGYGITQAIGTGGRDLSAQIEAVTA 237

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           + AL++L+ADE ++V+ F+SKPPA  VR K++   K  GKP VA FLG       D NV+
Sbjct: 238 IEALKLLAADEDTDVIVFISKPPAPEVRDKVIETFKILGKPVVANFLGDKKRENHD-NVF 296

Query: 301 FASSLDEAARLACLLS------------RVTARRNAIAPVSSGFICGLYTGGTLAAEAAG 348
           +  +L++ A     ++             +   ++ I       I GLY GGTLAAE   
Sbjct: 297 YTHTLEDTALKTVEIAEKYKISEKNIRKEIKEVKDIIENKEQRSIKGLYCGGTLAAETGM 356

Query: 349 LLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKP 408
           ++  + G+E   +H  GMML  + H+IIDLGDDFYT GRPHPMIDP++R  ++ ++  +P
Sbjct: 357 IIRDYYGIEDSGSHDKGMMLHYNGHEIIDLGDDFYTQGRPHPMIDPSIRVDMVYEMAKRP 416

Query: 409 QVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQI 468
           +  V+LLD VIG+G   D A       ++        + +  IA++TGTE DPQ  S+Q 
Sbjct: 417 ETAVILLDNVIGYGGHEDMAGVFAPVIKEIKED-PAYKKIVFIASITGTENDPQKYSEQY 475

Query: 469 ATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAV-----------INIG 517
             LED+G  V  S  +AT +A  +I  L  +   +  +  E++ V           INIG
Sbjct: 476 KKLEDSGAVVCESNAQATRMAVEIIKSLEKSETNNIETGEESIEVKSNIINTEPVIINIG 535

Query: 518 LRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ 555
           L  FA  ++     V+ Y W+P AGG+K+LA +L++L+
Sbjct: 536 LGKFAETVKKYDAKVIQYNWAPTAGGDKRLAEILKKLR 573


>UniRef50_Q47208 Protein fdrA n=96 Tax=Proteobacteria RepID=FDRA_ECOLI
          Length = 555

 Score =  508 bits (1307), Expect = e-142,   Method: Composition-based stats.
 Identities = 555/555 (100%), Positives = 555/555 (100%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT
Sbjct: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL
Sbjct: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI
Sbjct: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
           AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA
Sbjct: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW
Sbjct: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300

Query: 301 FASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADD 360
           FASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADD
Sbjct: 301 FASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADD 360

Query: 361 THQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIG 420
           THQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIG
Sbjct: 361 THQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIG 420

Query: 421 FGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVS 480
           FGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVS
Sbjct: 421 FGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVS 480

Query: 481 SLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPV 540
           SLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPV
Sbjct: 481 SLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPV 540

Query: 541 AGGNKKLARLLERLQ 555
           AGGNKKLARLLERLQ
Sbjct: 541 AGGNKKLARLLERLQ 555


>UniRef50_C0WN22 Membrane protein n=1 Tax=Lactobacillus buchneri ATCC 11577
           RepID=C0WN22_LACBU
          Length = 587

 Score =  472 bits (1214), Expect = e-131,   Method: Composition-based stats.
 Identities = 222/583 (38%), Positives = 331/583 (56%), Gaps = 32/583 (5%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           M+H  I+K  +QDS+ LM+++  L   + V++V VMMGTPANK +  T G   D+ + A 
Sbjct: 1   MLHTIIEKNSYQDSIVLMLLTNYLETLDGVNNVQVMMGTPANKDIFKTGGLATDELDEAK 60

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQ-LAQGSGSSQALTQVRRWDSACQKLPDAN 119
           P+D+ + I +E+ D  +   ++ + ++ L      G+ +  A  +V+ WD A +   DA 
Sbjct: 61  PSDMVIVIDTESDD--LIDEVVDKAKDYLDAQGKAGNENETADERVKTWDKALELGKDAP 118

Query: 120 LALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSM 179
           +ALISV G YAA    +ALD   NV  FSDNV++EDE +LK  A EKGL++MGPDCGT +
Sbjct: 119 VALISVPGVYAAVEVEKALDAGKNVFCFSDNVSMEDEARLKQMAHEKGLVLMGPDCGTGI 178

Query: 180 IAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGIS 239
             G PLAFAN + +G+IG++GASGTGIQE+ + I   G G+T+AIG GGRDL  ++ G +
Sbjct: 179 ANGIPLAFANRVRKGSIGMVGASGTGIQEVSTIIHKLGAGVTNAIGTGGRDLKADIQGTT 238

Query: 240 ALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENV 299
              ++ +L  D   +V+  +SKPPA  VR  +++ ++AT KP VA+FLG     + +E +
Sbjct: 239 FKDSVALLDQDPDVKVIVAISKPPAPEVRDDVLSLLRATNKPVVAIFLGE-KPTSHEEGL 297

Query: 300 WFASSLDEAARLACLLSRVTAR---------RNAIAPVSSGFICGLYTGGTLAAEAAGLL 350
           + A +L+E AR+A  L                +        +I G Y+GGTLA EAA L+
Sbjct: 298 YRAYTLEETARIAVDLLNGKTPGSYDDELKIPDIQLEPQQKYIKGYYSGGTLAYEAATLM 357

Query: 351 AGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQV 410
              L + A+D    G +L  + +++IDLGDD YT GRPHPMID T R +++ + G  PQ 
Sbjct: 358 NDALNLNAEDAGD-GFILQKEGYEVIDLGDDVYTQGRPHPMIDATKRKEMMVEAGNDPQT 416

Query: 411 RVLLLDVVIGFGATADPAASLVSAWQKACA-ARLDNQPLYAIATVTGTERDPQCRSQQIA 469
             +L+D+V+G+GA  + A  L  A +K  A A+   + L  I T+ GT+ DPQ  ++Q  
Sbjct: 417 AAILIDIVLGYGAHDNMAGELAPAIKKVIADAKNQGRNLPVIGTIVGTDLDPQNYAEQKD 476

Query: 470 TLEDAGIAVVSSLPEATLLAAALI--------HPLSPAA---------QQHTPSLLENVA 512
            LE AG+ +  S  +A   A AL+         P+ P            +    +L    
Sbjct: 477 ILEAAGVILCQSNAQAVKTALALVGKPIFGEPKPIRPKKSSTAVMPEVSEDLRQMLTATK 536

Query: 513 VINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ 555
            IN+GL SF+  +       V ++W PVAGGN  L + L  L 
Sbjct: 537 FINVGLDSFSEAINENGGDAVQFEWHPVAGGNVTLQKALNYLN 579


>UniRef50_A6TL44 FdrA family protein n=3 Tax=Clostridiales RepID=A6TL44_ALKMQ
          Length = 525

 Score =  461 bits (1186), Expect = e-128,   Method: Composition-based stats.
 Identities = 172/528 (32%), Positives = 281/528 (53%), Gaps = 30/528 (5%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           +   I+K  + DSV+LM+I++++ +   + +V V MGT  NK L       + +     P
Sbjct: 3   LKYAIRKNTYYDSVTLMLITKEVKKLPGIQEVLVGMGTELNKELASHLSLSNKEIQGLNP 62

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
           ND  V   + +      +A++++++  L +            +     +A +   DANL 
Sbjct: 63  NDFFVTALASSD--LSMEAVLKEVDTLLTKKKT---QGDGDYRPPTLGAALKYQLDANLV 117

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           L+S+ GEYA +   +AL ++++VM+FSD +++ DE +LK  A+E+ LL+MGPDCGT++I 
Sbjct: 118 LVSIPGEYAFDEVEKALHQDIHVMLFSDQMSMADERRLKEIAKERQLLMMGPDCGTAIIN 177

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
             PLAFANV+ +GNIG++GASGTGIQE+   I   GEG++  IG GGRDL +E+GGI   
Sbjct: 178 QVPLAFANVVRKGNIGIVGASGTGIQEVSILIHRLGEGVSQVIGTGGRDLKKEIGGIMMQ 237

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
             +E L  D ++ V+  +SKPP E V  +++  +  + KP V  F+G    +        
Sbjct: 238 QGIEALQNDPETGVIVLISKPPDEEVAERVLALIAHSEKPVVVNFIGGHLNLIEKYGRTP 297

Query: 302 ASSLDEAARLACLLSRVTARRN-------------------AIAPVSSGFICGLYTGGTL 342
            ++L++AA+ A  L +  A R+                    +      +I GLYTGGTL
Sbjct: 298 CTTLEDAAQKAVALLKGQAPRDFNGFTLSQERVSKMVCNEVKVFHHQQSYIRGLYTGGTL 357

Query: 343 AAEAAGLLAGHLGVEADDTH-----QHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLR 397
           A E   LL+  LG    ++      Q   + ++  H  +DLG+D +T G+PHPMIDP+ R
Sbjct: 358 ANETIKLLSEELGGIYSNSPLRPEYQLLNVEESFQHTCLDLGEDGFTRGKPHPMIDPSTR 417

Query: 398 NQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARL-DNQPLYAIATVTG 456
            Q         +V ++L+D V+G+G+  DP   ++    +         + L  IA++ G
Sbjct: 418 LQRFVKEANDEEVAMILMDFVLGYGSHEDPVGEMLPVIIEEKRRLNQRGRHLCVIASICG 477

Query: 457 TERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHT 504
           TE DPQ   +    LE+AG+ V+ S  +A  LA+ ++   +   + H 
Sbjct: 478 TEEDPQDLKKSQQRLEEAGVLVMPSNAQAARLASLIMKNQNLRRENHV 525


>UniRef50_C5BXU8 FdrA family protein n=1 Tax=Beutenbergia cavernae DSM 12333
           RepID=C5BXU8_BEUC1
          Length = 562

 Score =  459 bits (1181), Expect = e-127,   Method: Composition-based stats.
 Identities = 265/564 (46%), Positives = 352/564 (62%), Gaps = 13/564 (2%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           M+   IK   +QDSVSLM++S +LS  + V+ VS+MMGTPANK +   TGF  D+   A 
Sbjct: 1   MLQTIIKPNTYQDSVSLMMLSTQLSGLDAVERVSIMMGTPANKEIFRDTGFGSDELEGAG 60

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           P+D+ +A+  EA  AG A  I  ++ E LK  A  + S+    +VR  D A   LPDANL
Sbjct: 61  PSDLVIAL--EADGAGAADLISGRVAEFLKSQAS-AASATTYPRVRSLDRALTALPDANL 117

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           AL+S+ GE AA   ++ LD++L+V +FSDN+ ++DE++LK +ARE+GLL+MGPDCGT  +
Sbjct: 118 ALVSIPGEQAAPEIDRLLDKDLHVFVFSDNLAVDDEVRLKHKARERGLLMMGPDCGTGSL 177

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            G PLAF N++  G+IG++GASGTG QE+  QI  AG G++ AIGLGGRDLS +VG ++ 
Sbjct: 178 GGLPLAFTNIVTPGSIGIVGASGTGTQEVMVQIDRAGGGVSQAIGLGGRDLSEKVGAVTC 237

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           L AL  L AD  + V+  VSKPPA +VR  +++  +    P VA+ LG  PAV  D NV 
Sbjct: 238 LQALRALDADPGTSVITLVSKPPAPSVRETVLDVCQELATPVVAILLGEQPAVEVDGNVH 297

Query: 301 FASSLDEAARLACLLSRVTARRNAIA---PVSSGFICGLYTGGTLAAEAAGLLAGHLGVE 357
           FA++LDEAARLA  L+       A A         I GL+ GGTL +EAA LL+  LGV 
Sbjct: 298 FAATLDEAARLAVSLAGTVTDEEAPAVELAPGQRTITGLFCGGTLTSEAAILLSRGLGVP 357

Query: 358 ADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDV 417
            D  H  G ML  D H +IDLGDD YT GRPHPMIDP+LR Q+I D     Q+ VLLLDV
Sbjct: 358 TDAEHADGYMLHHDGHTVIDLGDDAYTQGRPHPMIDPSLRAQMIRDAFDDRQLAVLLLDV 417

Query: 418 VIGFGATADPAASLVSAWQKAC-AARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGI 476
           V GFG+  DPA ++V A +    AAR D + +  +A+V GTE+DPQ  S+Q  TL++AG+
Sbjct: 418 VTGFGSHEDPAGAIVGAIEAGREAARADGREVVVVASVCGTEKDPQPLSEQTRTLQEAGV 477

Query: 477 AVVSSLPEATLLAAALIHPLSPAAQ------QHTPSLLENVAVINIGLRSFALELQSASK 530
            V+ S   AT  A  ++                   + E   V+N+GL SFA  LQ    
Sbjct: 478 VVLGSNAAATRYALGVVSRTGERRTPAEIPEPTRRLVSEAPRVVNVGLASFADTLQERGG 537

Query: 531 PVVHYQWSPVAGGNKKLARLLERL 554
            VV Y WSP+AGGN +L R+L  L
Sbjct: 538 QVVQYTWSPLAGGNARLQRILAAL 561


>UniRef50_UPI000182709D FdrA family protein n=1 Tax=Enterobacter cancerogenus ATCC 35316
           RepID=UPI000182709D
          Length = 513

 Score =  427 bits (1098), Expect = e-118,   Method: Composition-based stats.
 Identities = 204/512 (39%), Positives = 283/512 (55%), Gaps = 29/512 (5%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
              IKK  + DSVSLM +S K ++   V+   V M T  NK +L   G    +   A   
Sbjct: 4   KIVIKKNTWFDSVSLMSVSTKANKLPGVEQAVVAMATEMNKGVLHNLGLLTPELAEAKNG 63

Query: 63  DICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           D+ + I+ EAA+     AI     EAL    + +GS +A  +     SA    PDANLA+
Sbjct: 64  DLMIVIKGEAANDETLAAI-----EALFTRKESAGSHEA--RYATIASAKAHRPDANLAV 116

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG 182
           ISV G +AA  A QAL+ +LNVM+FSDNV+L+DE+ LK  A +KGLL+MGPDCGT++I G
Sbjct: 117 ISVNGTFAAREARQALENDLNVMLFSDNVSLDDELALKQLAHQKGLLMMGPDCGTAIING 176

Query: 183 TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALT 242
             L FAN +  G+IG++GASGTG QEL  +I   G G++  IG GGRDLS ++GG+  L 
Sbjct: 177 AGLCFANAVCRGSIGIVGASGTGSQELSVRIHEFGGGVSQLIGTGGRDLSEKIGGLMMLD 236

Query: 243 ALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFA 302
           A+ ML ADE ++ +  +SKPPA AV  K++   +A  KP +A FLG     A ++ + FA
Sbjct: 237 AIAMLEADENTQAIVLISKPPAPAVAEKVLARARACRKPVIACFLGRNAPPADEDGLQFA 296

Query: 303 SSLDEAARLACLLSR---------------VTARRNAIAPVSSGFICGLYTGGTLAAEAA 347
               EAA  A LL+                +   R    P    +I GL+ GGTL  EA 
Sbjct: 297 RGTKEAALKAVLLTGIKQESLDLHPLNWPLIEEVRARQTP-QQKYIRGLFCGGTLCDEAM 355

Query: 348 GLLAGHLG-----VEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIA 402
                        ++ D   +   +  + +H  +D GDD +T GRPHPMIDP+ R   + 
Sbjct: 356 FAALEKYDDVYSNIQPDPAKRLSDINVSQAHTFLDFGDDDFTHGRPHPMIDPSNRITRLL 415

Query: 403 DLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACA-ARLDNQPLYAIATVTGTERDP 461
                P+V V+++D V+GFGA  DP   ++ A Q+A A A+ DN+PL  +  V GT++DP
Sbjct: 416 QEARDPEVAVIVMDFVLGFGAHDDPVGVMIDAIQEAQAIAKADNRPLVILGYVLGTDQDP 475

Query: 462 QCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
           Q  +QQ   L DAG+   SS     LLA   +
Sbjct: 476 QSLAQQCERLTDAGVIWASSSTNTGLLAREFV 507


>UniRef50_P77187 Uncharacterized protein yahF n=55 Tax=Proteobacteria
           RepID=YAHF_ECOLI
          Length = 515

 Score =  418 bits (1073), Expect = e-115,   Method: Composition-based stats.
 Identities = 186/513 (36%), Positives = 270/513 (52%), Gaps = 27/513 (5%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           +   IK   + DSVSLM IS + ++ + V+   V M T  NK +L   G    +   A  
Sbjct: 3   VKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNKGVLKNLGLLTPELEQAKN 62

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
            D+ + I  ++      + ++ ++EE        + S     +     SA + +P++NLA
Sbjct: 63  GDLMIVINGKS--GADNEQLLVEIEELFNTK---AQSGSHEARYATIGSAKKHIPESNLA 117

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           +ISV G +AA  A QAL  +LNVM+FSDNV++EDE+ LK  A EKGLL+MGPDCGT++I 
Sbjct: 118 VISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAHEKGLLMMGPDCGTAIIN 177

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G  L F N +  GNIG++GASGTG QEL  +I   G G++  IG GGRDLS ++GG+  L
Sbjct: 178 GAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQLIGTGGRDLSEKIGGLMML 237

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
            A+ ML  D ++E++A +SKPPA AV  K++   +A  KP V  FL        ++ + F
Sbjct: 238 DAIGMLENDPQTEIIALISKPPAPAVARKVLERARACRKPVVVCFLDRGETPVDEQGLQF 297

Query: 302 ASSLDEAARLACLLSRVTA---------------RRNAIAPVSSGFICGLYTGGTLAAEA 346
           A    EAA  A +LS V                  R  + P    +I GL+ GGTL  E 
Sbjct: 298 ARGTKEAALKAVMLSGVKQENLDLHTLNQPLIADVRARLQP-QQKYIRGLFCGGTLCDET 356

Query: 347 AGLLAGHLG-----VEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLI 401
              +    G     ++ D   +   +  +  H  +D GDD +T G+PHPMIDPT R   +
Sbjct: 357 MFAVMEKHGDVYSNIQPDPEFRLKDINRSIKHTFLDFGDDDFTNGKPHPMIDPTNRISRL 416

Query: 402 ADLGAKPQVRVLLLDVVIGFGATADPAASLVSA-WQKACAARLDNQPLYAIATVTGTERD 460
            +    P+V V+++D V+GFG+  DP  S +    +    A  + + L  +A V GT+ D
Sbjct: 417 IEEARDPEVAVIVMDFVLGFGSHEDPVGSTIETIKEAKAIAAAEGRELIILAYVLGTDLD 476

Query: 461 PQCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
                QQ   L DAG+ + SS     LLA   I
Sbjct: 477 TPSLEQQSQMLLDAGVILASSSTNTGLLAREFI 509


>UniRef50_C0D6C1 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0D6C1_9CLOT
          Length = 517

 Score =  416 bits (1070), Expect = e-114,   Method: Composition-based stats.
 Identities = 174/517 (33%), Positives = 281/517 (54%), Gaps = 23/517 (4%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           + + +    ++DSV LM ++  + + E V++  V++ T ANK +L+  G   ++   ATP
Sbjct: 3   LKSKVFPNSYRDSVLLMKMAGMVRKIEGVENAEVIIATEANKGILEFNGLLTEEIRKATP 62

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
           ND+ V++ +   D  + +  +  +E+ +    +     +     +    A    P+A+LA
Sbjct: 63  NDLVVSVIA--GDETVIEKAIAAVEDMIFNGLEDDKGGKVTYSAKSIAGALAMEPEADLA 120

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           ++S+ G    + A + LD  +N+++FSDNV +EDE++LK +A E GL+VMGPDCGT+++ 
Sbjct: 121 ILSIPGPLVKKDAMKLLDSGVNLLIFSDNVPIEDELELKRKADEMGLMVMGPDCGTAIVR 180

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G  LAFAN + +G IG++ ASGTG+QE+   I   G+GI+HA+G G  D+   +GGIS  
Sbjct: 181 GASLAFANKVRQGKIGMVCASGTGLQEVAVLIHNLGQGISHALGTGSNDVKDAIGGISMK 240

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
             L+ L  D  +E++  VSKPP +A    +    K   KP +  FLG +  V RD NV++
Sbjct: 241 RGLKWLEQDGSTELIVVVSKPPQKATMENLKEEFKKCRKPVIVNFLGSSQPVKRDGNVYY 300

Query: 302 ASSLDEAARLACLLSRVTARRNAIAPV---------------SSGFICGLYTGGTLAAEA 346
             +L+E A  A  L+  T   +   P                  G++  LYTGGTL  EA
Sbjct: 301 TDTLEETALKALELAGETVDDSVAVPEDILEDIRRERELHRHKGGYMRALYTGGTLGTEA 360

Query: 347 AGLLAGHLGVEADDTHQHGMM-----LDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLI 401
           A +    L     +    G+        +  + I+DLG D +T+G+PHPMI+P ++NQ +
Sbjct: 361 AIICRDILSGLTTNLTVPGVEKMADYNVSAKNCILDLGADEFTLGKPHPMIEPEMKNQRL 420

Query: 402 ADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACA-ARLDNQPLYAIATVTGTERD 460
               A P+  V+LLD V+G+G  ADPA + +    KA   A    + +  +A+VTGT+ D
Sbjct: 421 LKEAADPETAVILLDFVLGYGVNADPAGNTLYEIDKAREIAESQGRHITIVASVTGTDED 480

Query: 461 PQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLS 497
           PQ R +QI  L+D G+ V+ S  +A   A  ++    
Sbjct: 481 PQNREEQIRVLKDHGVLVLPSNAQAVRAAVEIVKECR 517


>UniRef50_C2GZK2 Bacterial FdrA protein n=28 Tax=Bacteria RepID=C2GZK2_ENTFA
          Length = 519

 Score =  407 bits (1047), Expect = e-112,   Method: Composition-based stats.
 Identities = 188/522 (36%), Positives = 272/522 (52%), Gaps = 26/522 (4%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           I   IK+  + DSV+LM IS + +E   V    + MGT  N  ++   G +    ++ T 
Sbjct: 3   IQTVIKENAYFDSVTLMTISTRANELAGVKTAMIGMGTDMNLEVIRNVGLYTPALDHVTT 62

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
            D+   I  +  D   ++ I+QQ++E   +  + + S       +  DSA  + PDANL 
Sbjct: 63  GDLL--IVLDLDDQANSEEILQQVDELFTKKKKTASSEVT---YKTLDSALHEEPDANLV 117

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           +ISV G++AA  A++ALD+  +VM+FSDNVT+++E+ LK +A EK L VMGPDCGT++I 
Sbjct: 118 VISVNGKFAAREAHKALDQQKHVMLFSDNVTVDEELALKQKAHEKELFVMGPDCGTAIIN 177

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G  L FAN +  G+IG++GASGTG QE+  QI   G GI+  IG GGRDLS E+GG+  L
Sbjct: 178 GVGLCFANEVRSGDIGIVGASGTGSQEVSVQIHKYGYGISQLIGTGGRDLSAEIGGLMML 237

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
             L+ L  DE+++ +  +SKPPA  V  KI+  +  + KP V  F+G      + +NV F
Sbjct: 238 DGLDALMVDEQTKAILLISKPPAPEVTEKILKKLAVSTKPVVIYFIGSEQTERKIDNVTF 297

Query: 302 ASSLDEAARLACLLSRVTARRN---------------AIAPVSSGFICGLYTGGTLAAEA 346
           A+S  +A +     S+                          S  F+ GL+ GGTL  E 
Sbjct: 298 ATSSLDAVQKVIQFSQTQEAETSLYQNPTGATLTAIQQQQAPSQKFVRGLFCGGTLCDEL 357

Query: 347 AGLLAGHLGVEADDTH-----QHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLI 401
              L         + H     Q      + +H +ID GDD +T GRPHPMIDPT R   I
Sbjct: 358 LYALTEVSDDVYSNIHKIPERQLANPDHSQAHTLIDFGDDRFTEGRPHPMIDPTSRITRI 417

Query: 402 ADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACA-ARLDNQPLYAIATVTGTERD 460
                 P+V VL LD  +G+G+  +P   L  A ++A A A+ D + L  I  V GTE D
Sbjct: 418 LQEAKDPEVAVLALDFELGYGSHENPVGVLAEALKEAKAIAKADGRELAIIGYVLGTEED 477

Query: 461 PQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQ 502
           PQ   +Q   LED  + VV S  +        +   +   Q+
Sbjct: 478 PQDIHEQRKILEDLEVLVVDSSHQLCEATKTFVKGANEHEQK 519


>UniRef50_Q2RGM5 FdrA n=1 Tax=Moorella thermoacetica ATCC 39073 RepID=Q2RGM5_MOOTA
          Length = 520

 Score =  404 bits (1038), Expect = e-111,   Method: Composition-based stats.
 Identities = 207/523 (39%), Positives = 281/523 (53%), Gaps = 28/523 (5%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           +I   IK   +QDSV LM +S +L + + V   SV+M T  NK+ L   G    +   A 
Sbjct: 2   VIRWLIKPKMYQDSVKLMKLSAELRKQDGVKQASVIMATEMNKSTLQDIGMLVPEVAAAN 61

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
            +D+ + +   A     AQ  ++  E+ L + A+           +   SA + LP ANL
Sbjct: 62  ADDLAIIV--AADTEEQAQKAVELAEKLLNR-AEVQQGETKQQFPKTLRSAVEALPGANL 118

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           ALISV G YAA  A +AL+  LNV +FSDNVTLEDE++LK    +KGLLVMGPDCGT++I
Sbjct: 119 ALISVPGTYAAAEALKALNLGLNVHLFSDNVTLEDEVRLKQIGTKKGLLVMGPDCGTAII 178

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            G PLAFANV+  G IG++GASGTGIQE    I   G GI+HAIG GGRDL  EVGG   
Sbjct: 179 DGVPLAFANVVARGKIGIVGASGTGIQEATVLIERLGGGISHAIGTGGRDLLDEVGGQMM 238

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           L  +++L  D  +EV+  +SKP       KI++ +K   KP V   L       +   V 
Sbjct: 239 LLGIDLLEDDPATEVILLISKPAGPRTANKILDRVKQCKKPVVVNLLKGDLNAIQSAGVV 298

Query: 301 FASSLDEAARLACLLS------------------RVTARRNAIAPVSSGFICGLYTGGTL 342
            A+++++AA  A  L+                  ++    + + P +  +I GL+TGGTL
Sbjct: 299 GAATIEDAAYKAVALANGEEAVAMPENYWGDYSKQIAMLESQLGP-NQRYIRGLFTGGTL 357

Query: 343 AAEAAGLLAGHLGVEADDTH-----QHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLR 397
           A EA  +L+  +G    +       +      +  H I+DLGDD +T GRPHPMIDP  R
Sbjct: 358 ADEAMVILSDIVGDIFSNIPLKPELKLPSARKSHKHTIVDLGDDEFTRGRPHPMIDPLPR 417

Query: 398 NQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGT 457
           N+ +    A P+V V+L DVV G+G+ ADPA  L  A  +A  A   N P   IA V GT
Sbjct: 418 NERLMQEYADPEVGVILCDVVTGYGSHADPAGELARAVARARDAYPSNNP-AVIAFVCGT 476

Query: 458 ERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
           E DPQ  S+Q+  LE  GI V+ S  EA   A  +I       
Sbjct: 477 EADPQPLSEQVKVLEKEGIFVLPSNAEAARAAGRIIKLHESRR 519


>UniRef50_A8VR79 Phage Terminase n=3 Tax=Firmicutes RepID=A8VR79_9BACI
          Length = 519

 Score =  404 bits (1037), Expect = e-111,   Method: Composition-based stats.
 Identities = 189/522 (36%), Positives = 280/522 (53%), Gaps = 30/522 (5%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
              I+K  + DSV+LM ++ K+ + + V D  V M T  NK L    G   D+   A  N
Sbjct: 4   QVIIRKNAYYDSVTLMSLASKIEQLDGVHDAIVAMATAMNKELAGDIGLVTDEVEAAGDN 63

Query: 63  DICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           D+ +A+ +E   A   +     +E A  +      + Q          A +   +ANLA+
Sbjct: 64  DLLLAVSAENEKA--LEEAFTAIEAA-FEAKSSQANKQTEKTYTNTKEALRDHEEANLAI 120

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG 182
           ISV+GE+AA  A  AL + L+VM+FSDNV++EDE +LK   R KGL VMGPDCGT+++ G
Sbjct: 121 ISVSGEFAAREAEIALKKGLHVMIFSDNVSVEDERRLKELGRNKGLFVMGPDCGTAILNG 180

Query: 183 TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALT 242
           T L FAN +  GNIG++ ASGTG+QE+  QI   G G++  IG GGRDLS+++GG+  L 
Sbjct: 181 TGLCFANSVRRGNIGLVAASGTGLQEVTVQIDRLGGGVSQGIGTGGRDLSKDIGGLMMLQ 240

Query: 243 ALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFA 302
            ++ L  D  ++V+  +SKPPA+ V+  ++  +KA+ KP V  F+   PA A      F 
Sbjct: 241 GIKALEEDPDTDVIVLISKPPAKEVQDLVLEQVKASRKPVVISFIDGDPAAAVSAGAIFG 300

Query: 303 SSLDEAARLACLLSRVTARRNAIAPV-------------------SSGFICGLYTGGTLA 343
            SL + A  A  LS+     +  A                     S   I GLY GGTL 
Sbjct: 301 YSLTDTAIKAVALSKGEEAPDKPADQFDKEAWETVLNGVREKRSDSQIDIRGLYGGGTLC 360

Query: 344 AEAAGLLA-GHLGVEADDTHQHGMML----DADSHQIIDLGDDFYTVGRPHPMIDPTLRN 398
           AEA  ++    L V+++   +    L    +++ H ++DLG+D +TVG+PHPMIDPT RN
Sbjct: 361 AEALSIMRQEGLSVKSNVAKREEEKLFNTRESEGHVLLDLGEDEFTVGKPHPMIDPTTRN 420

Query: 399 QLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTE 458
           Q +    A  +  V+L+D  +G+G+  DP    +   ++A   R++N  L  ++ V GT 
Sbjct: 421 QRLLQEAADEKTAVILMDFELGYGSHEDPVGVSLPFIEEA---RVNNPSLAIVSYVCGTA 477

Query: 459 RDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
            DPQ      + L +AG+AV +S  EA  LA  L      +A
Sbjct: 478 TDPQGLESAESRLREAGVAVANSNVEAVRLAVHLQAAREVSA 519


>UniRef50_Q7BSA0 YahF/FdrA-like protein n=3 Tax=Proteobacteria RepID=Q7BSA0_ACIAI
          Length = 514

 Score =  392 bits (1007), Expect = e-107,   Method: Composition-based stats.
 Identities = 193/514 (37%), Positives = 277/514 (53%), Gaps = 16/514 (3%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           I   +++  +QDSV+LM +S  L   + V + S+MMGT  N  ++   G      N+A P
Sbjct: 3   IVVEVRRNTYQDSVTLMRLSSDLLAEDGVTNASIMMGTAGNIEIMREGGLDAPALNDARP 62

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
            D+ +AI + + DA  A+  +++   AL   A  +       +          +   NL 
Sbjct: 63  TDLVIAIVAASEDA--ARTAIEKAIAALNTDASTASDGGGAQKRAISSVMGAVVEGVNLT 120

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           LISV GEYAA  A +AL   ++V +FSDNV++E EI LK  A  KGLL+MGPDCGT++I 
Sbjct: 121 LISVPGEYAAAEAMKALKAGMHVHLFSDNVSVEKEIALKDVAISKGLLMMGPDCGTAIIN 180

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G P+ FAN +  G IGVI ASGTG QE+ S I   G GI+ A G GGRDLS  V G  A 
Sbjct: 181 GVPVGFANAVRRGRIGVIAASGTGAQEVTSLIHELGSGISQAFGTGGRDLSSAVKGRMAR 240

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
            AL+ L  D+ ++V+  +SKPPA  V   I++  K T KP V  FLG    + RD  +  
Sbjct: 241 FALKALLDDDMTDVIVLISKPPAPEVAASILDTAKGTSKPIVVCFLGGDSKMVRDHGLIP 300

Query: 302 ASSLDEAARLACLLSRVTARRNAIAPV--------SSGFICGLYTGGTLAAEAAGLLAGH 353
           A +L++AAR A      +   +  AP            ++ GL++GGT   EA  LL   
Sbjct: 301 AETLEDAARQAVRAETGSDTGSRYAPAPTLPKLSKEQKYVRGLFSGGTFCYEALLLLREF 360

Query: 354 LGVEADDTH-----QHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKP 408
           +G  + +T      +      +  H  ID G+D +TVGRPHPM+D   RN  I      P
Sbjct: 361 VGDVSSNTPINKQMKLKNNNISTGHVCIDFGEDEFTVGRPHPMLDFRFRNDRIVQEARDP 420

Query: 409 QVRVLLLDVVIGFGATADPAASLVSAWQKACA-ARLDNQPLYAIATVTGTERDPQCRSQQ 467
           +  V+LLD+V+G+GA A+PA +L+ A +KA   AR + + L  +A+V GT  D Q   QQ
Sbjct: 421 ETAVILLDLVLGYGANANPAGALMPAIRKAMEVARAEGRTLPIVASVCGTSDDLQGLEQQ 480

Query: 468 IATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQ 501
            A L +AG+ ++SS  +A+  A  +        +
Sbjct: 481 EAALREAGVTILSSNAQASRFAGKIAQVAQITQK 514


>UniRef50_B9KYM7 Protein fdrA n=1 Tax=Thermomicrobium roseum DSM 5159
           RepID=B9KYM7_THERP
          Length = 514

 Score =  389 bits (1000), Expect = e-106,   Method: Composition-based stats.
 Identities = 198/506 (39%), Positives = 287/506 (56%), Gaps = 29/506 (5%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           ++   I+   + DSV+LM ++  ++    VD  +++MGT AN  LL  +G W +     +
Sbjct: 2   VVRIRIEPNSYFDSVALMAVASVVNRLPGVDLAALLMGTSANLELLRDSGLWDERLETVS 61

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           PND+ +A+R+   D   A+  + +    L+  A+ S  S+A   +R   +A +++  A++
Sbjct: 62  PNDLVIAVRAS--DDAAAERAIDEAVHRLRSSARTSQVSEAKVTLRTLRTALRQVSQASV 119

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
             ISV G YA   A +AL  + +V +FSDNV +E+E++LK  A+E+GLL+MGPDCGT+ I
Sbjct: 120 VAISVPGPYAPIEAEEALRADRHVFLFSDNVPIEEEVRLKELAQERGLLLMGPDCGTAFI 179

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
           AG  L F N +  G IG++ A+GTG+Q+L S I   G GI+H IG GGRDL   VGG + 
Sbjct: 180 AGLGLGFMNAVRRGPIGIVAAAGTGLQQLASLIDWFGSGISHGIGTGGRDLDARVGGRTM 239

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
           L  LE L+ D  ++V+  VSKPPA  V  K++    A GKP VA F+G T  V   E V 
Sbjct: 240 LAGLEALAHDPATQVIVLVSKPPAPEVAEKVLAFAAACGKPVVATFIGQTAPV--TEGVH 297

Query: 301 FASSLDEAARLAC------------------LLSRVTARRNAIAPVSSGFICGLYTGGTL 342
            A++L EAARLA                    L+RV A R+ +AP    ++ GLY+GGTL
Sbjct: 298 VAANLTEAARLAVHLATGQSLADLDLPRRQEALARVRAERSRLAPT-QRYLRGLYSGGTL 356

Query: 343 AAEAAGLLAGHLGVEADDTH-----QHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLR 397
             EA  LL   +G    +       +      ++ H  +DLG D +TVGRPHPMID T+R
Sbjct: 357 CDEAMVLLQPRIGPIRSNIPLQPELRLTDPHRSEEHTFVDLGSDEFTVGRPHPMIDQTIR 416

Query: 398 NQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKAC-AARLDNQPLYAIATVTG 456
            +      A P V  ++LD+V+G+GA +DPAA L  A ++A   A    + L  I  + G
Sbjct: 417 LERFRREAADPTVAGIVLDLVLGYGAASDPAAELAPAIREARVEAERTGRILPCIVALVG 476

Query: 457 TERDPQCRSQQIATLEDAGIAVVSSL 482
           T+ DPQ  ++Q  TLEDAG  VV S 
Sbjct: 477 TQSDPQDYARQRRTLEDAGAIVVPSN 502


>UniRef50_Q0TAN3 YahF/FdrA-like protein n=18 Tax=Gammaproteobacteria
           RepID=Q0TAN3_ECOL5
          Length = 519

 Score =  389 bits (1000), Expect = e-106,   Method: Composition-based stats.
 Identities = 200/517 (38%), Positives = 283/517 (54%), Gaps = 30/517 (5%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           +   +    +QDSVSLM IS ++S+   +   SV+MGTP N   L   G  ++   NA+P
Sbjct: 3   VKYKVFSNLYQDSVSLMQISAQISKLPGIQQASVVMGTPNNLEQLRDAGLGNEI--NASP 60

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
           ND+ +A+  E      A  + QQ      +    + S     +    + A +  P+ANLA
Sbjct: 61  NDLVIAVMGEEDICNEALVLAQQ--RLTSKPDDETDSGIKSPEKVSLEMALEAEPEANLA 118

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           LISV G+YAA  A +AL+  +NVMMFSDNV++  E  +KT ARE+  +VMGPDCGT+++ 
Sbjct: 119 LISVPGDYAAAEAMKALNLGMNVMMFSDNVSIGQEKSIKTLARERQRIVMGPDCGTAIVN 178

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G PL FANV+  G IGVIGASGTG+QE+  +I   G GI+ A+G GG DLS E+GGIS L
Sbjct: 179 GIPLGFANVVKRGAIGVIGASGTGLQEVTCRIDQLGAGISQALGTGGHDLSEEIGGISML 238

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
            AL+ L+ D+++ V+  +SKPP+  V   I+   +A GKP V  FLG  P      N+  
Sbjct: 239 FALDALAQDDETRVIVLISKPPSPIVAQTILERAEACGKPVVVNFLGANPHDLARPNITA 298

Query: 302 ASSLDEAARLACLLSRVTARRN-----------------AIAPVSSGFICGLYTGGTLAA 344
           A++L  AA +A  L                            P     I G++ GGT   
Sbjct: 299 ATTLASAANIAVALLNDQPIPAVETEISCDDLTMLQNACQRLPAHRQAIRGVFAGGTFCY 358

Query: 345 EAAGLLAGHLGVEADDTHQHG-----MMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQ 399
           EA  +        A +T   G      +  ++ H +ID+GDD +T G+PHPMIDPTLRNQ
Sbjct: 359 EAQLICQQKGFSAASNTPVAGNRALANIWQSEDHTLIDMGDDDFTRGKPHPMIDPTLRNQ 418

Query: 400 LIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTER 459
            + +        V+L D+V+G+GA+  PA+ L+          ++N PL  IA V GTE 
Sbjct: 419 RLLNELNDSHTAVVLFDLVLGYGASTTPASELLDQLSHI---DMNNAPL-LIAHVCGTEA 474

Query: 460 DPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPL 496
           DPQ RSQQI  L++AG+ + SS  +A L A+ +    
Sbjct: 475 DPQIRSQQIRALQNAGVIIASSNAQAALWASTVAQTQ 511


>UniRef50_B0VJR0 FdrA n=1 Tax=Candidatus Cloacamonas acidaminovorans
           RepID=B0VJR0_9BACT
          Length = 505

 Score =  387 bits (995), Expect = e-106,   Method: Composition-based stats.
 Identities = 189/512 (36%), Positives = 281/512 (54%), Gaps = 21/512 (4%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           I A I  G + DSV LM+ISR+L   + V +   ++ T  N+ +L  +    ++ N+A+ 
Sbjct: 3   IKAKIIAGKYLDSVKLMLISRELRSLKGVLEAVAIVATSENREILKASDMLAEEINSASE 62

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
           NDI + I+++ A    A   + + EE + + +    +   + Q    + A   L  A+L 
Sbjct: 63  NDIVIVIKADNAKN--AAEAINKAEELINKPSTNEYNQTPIPQAFTLEKAIATLGGADLC 120

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           LIS+AG+YAA  A +AL++ L++++FSDNV++EDE+ LK +A +KGLL+MGPDCGT+++ 
Sbjct: 121 LISIAGKYAAAEAEKALEKGLHILLFSDNVSIEDELSLKQKALKKGLLMMGPDCGTAILN 180

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G PLAFAN +P G IG++ ASGTG+QE+ + IA    GI+ A G GGRD  +E+GG+   
Sbjct: 181 GVPLAFANNVPRGKIGIVSASGTGLQEISTTIANLSGGISQAFGTGGRDGKKEIGGLMLT 240

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
             LE L  DE +EV+    KPP E V+ K+   +  + KP +A FL     V    N+++
Sbjct: 241 ACLEYLLEDENTEVIIVTGKPPCEEVQKKLWELISHSSKPVIANFL-IPMQVPELPNLYY 299

Query: 302 ASSLDEAARLACLLSRVTARRNAIAP------VSSGFICGLYTGGTLAAEAAGLLAGHLG 355
             SL E A  AC  + +  +   +A       +   ++ GLY+GGTL  EA  +   + G
Sbjct: 300 VRSLSETAFFACKKAGIEVKNAKLAEDFPLPKLRGPYLRGLYSGGTLCQEAIQVYLDNFG 359

Query: 356 VEADDT------HQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQ 409
            E  +        +         + IIDLG D +T+GRPHPMID +LR Q +A     P+
Sbjct: 360 CEPFNNVTDQAFFRLTDGWQTKENSIIDLGADEFTIGRPHPMIDYSLRLQKLAQEANDPK 419

Query: 410 VRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIA 469
           V ++LLDVV+GFGA  DPA  LV A QK          L  +  + GT+ DPQ R +Q  
Sbjct: 420 VGIILLDVVLGFGAHPDPAEELVPALQKL------PADLVVVCHLLGTDGDPQNRQKQKK 473

Query: 470 TLEDAGIAVVSSLPEATLLAAALIHPLSPAAQ 501
            LE AG  V +S   A       +     A  
Sbjct: 474 ELEKAGAYVFTSHHSACEFVCQCLRSYRSAKC 505


>UniRef50_D1B8P5 FdrA family protein n=1 Tax=Thermanaerovibrio acidaminovorans DSM
           6589 RepID=D1B8P5_THEAS
          Length = 517

 Score =  375 bits (963), Expect = e-102,   Method: Composition-based stats.
 Identities = 182/514 (35%), Positives = 269/514 (52%), Gaps = 31/514 (6%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
              + +  + DSV+LM +++++   E V   S+ MGT AN  +L   GF   +  +ATPN
Sbjct: 8   RLEVVERTYYDSVTLMRVAKEIGGMEGVSSASLSMGTDANLRILAAAGFDVSNL-SATPN 66

Query: 63  DICVAIRSEAADAGIAQAIMQQLEEALKQLA-QGSGSSQALTQVRRWDSACQKLPDANLA 121
           D+ +A+  E     +    + + +E L     +         + R  D A   +P+ANLA
Sbjct: 67  DLIIAVMGEQD---VLDLAVAKAKEYLSNPPWRQGQDGGESYKPRSLDGALTVMPEANLA 123

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           +ISVAG YA ++A   + ++LNVM++SDNV LE EI++K  A EKGLLVMGPDCGT +I 
Sbjct: 124 VISVAGRYAGDVAMDCIAKDLNVMLYSDNVPLEKEIEVKRAAAEKGLLVMGPDCGTVVIR 183

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G  +  AN  P G + ++ A+GTG+QE+  Q+A  G G  H IG GGRD+  +VGGI   
Sbjct: 184 GVAIGMANSCPTGPVSIVAAAGTGLQEVHVQLARRGVGTLHGIGTGGRDVKSQVGGIMVE 243

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWF 301
            A  +L  D + +VL  V KPPA  V  +I++  + + KP V  F+G      +   V+ 
Sbjct: 244 MASRLLLEDHEVQVLVIVGKPPAPEVEERILHLARGSSKPVVLGFVGGKAKGDQHP-VYI 302

Query: 302 ASSLDEA-----------------ARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAA 344
              L+E                  A +   +  + A    I P   G++ GLY+GGTL  
Sbjct: 303 CRELEETAAVAAALAKGEDVPQVRAAMDAQVEELKALAKRIGP-RKGYLRGLYSGGTLCY 361

Query: 345 EAAGLLAGHLGVEADDTH-----QHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQ 399
           EA  +    LG    +T      +    L +  H I+D G+D +T GR HPMID +LR  
Sbjct: 362 EAQLIARDILGPIHSNTPLEEHLKLEDSLRSVEHTIVDFGEDEFTQGRLHPMIDVSLRAS 421

Query: 400 LIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTER 459
              +    P+V V+L DVVIG+G   DPA  LV   +KA         +  +A+V GT  
Sbjct: 422 RFQEEVKDPEVGVVLFDVVIGYGCHPDPATGLVEGIRKAKEIC--GDRVVFVASVCGTPD 479

Query: 460 DPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
           D Q   +Q   LE+AG+ V+ S  +A+ LA+ L+
Sbjct: 480 DVQDADRQRRILEEAGVVVMDSNAKASRLASFLL 513


>UniRef50_C1D754 YahF/FdrA-like protein n=1 Tax=Laribacter hongkongensis HLHK9
           RepID=C1D754_LARHH
          Length = 512

 Score =  360 bits (925), Expect = 6e-98,   Method: Composition-based stats.
 Identities = 202/513 (39%), Positives = 277/513 (53%), Gaps = 25/513 (4%)

Query: 2   IHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATP 61
           +H  I +  ++DSV+LM +S  L+  + +   S +M TPAN ALL   G   D    A P
Sbjct: 3   LHLAILRNQYRDSVALMQLSAALARLDGITQASAVMATPANLALLSRAGLL-DTPPEAAP 61

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
           ND+ +A+  E        A +    +AL+     S    A         A  + PD+NLA
Sbjct: 62  NDLLIALEGE---EAAFDAALTHARQALEAKGGQSAGGPAELPANSLTMALSRQPDSNLA 118

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           LISV G YA   A +AL   LNVM+FSDNV+ EDE +LK  A   G +VMGPDCGT++I 
Sbjct: 119 LISVPGAYATAEAEKALRAGLNVMLFSDNVSGEDERRLKQLATGLGRIVMGPDCGTAIIH 178

Query: 182 GTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISAL 241
           G PLAFANV   G IG +GASGTG+Q++ + I   GEGI+ AIG GG DL+  VGG+S L
Sbjct: 179 GVPLAFANVCRAGAIGCVGASGTGLQQITTLIDTLGEGISQAIGTGGHDLAESVGGLSML 238

Query: 242 TALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA-VARDENVW 300
             +  L+ D+ + V+  VSKPPAEAV  K+++A  A GKP V  FLG  PA + +  N+ 
Sbjct: 239 AGIRALAEDDATRVIVLVSKPPAEAVARKVLDAAIAAGKPVVVNFLGADPARLPQHANLH 298

Query: 301 FASSLDEAARLACLLSRVTARRN--------------AIAPVSSGFICGLYTGGTLAAEA 346
           +A++L+ AAR+A    R    ++              A        + GLY+GGT   EA
Sbjct: 299 YATTLESAARMAVACVRGEPLQDTPPQPHPETAAALKARLQPQQTRLRGLYSGGTFCYEA 358

Query: 347 AGLLAGHLGVEADDT-----HQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLI 401
             +LA  L     +T          +  +  H +IDLGDD +T GRPHPMID  LRN+  
Sbjct: 359 TLMLADALPGLRSNTPTARAPAPDDVWHSAGHCLIDLGDDEFTRGRPHPMIDHRLRNERF 418

Query: 402 ADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLD-NQPLYAIATVTGTERD 460
               A   V V+L D+V+GFGA  DP A++     +      D  + +  +ATV GT  D
Sbjct: 419 LAEAADETVAVILFDIVLGFGAHDDPLAAMHDTLTEVRRLTADAGREVALVATVCGTAGD 478

Query: 461 PQCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
           PQ   +Q A     G+ + +S  EA  LA A++
Sbjct: 479 PQGFERQRAGFAALGVCLAASNAEAVALARAIV 511


>UniRef50_D0WIW7 Protein FdrA n=1 Tax=Slackia exigua ATCC 700122 RepID=D0WIW7_9ACTN
          Length = 488

 Score =  360 bits (924), Expect = 7e-98,   Method: Composition-based stats.
 Identities = 181/493 (36%), Positives = 258/493 (52%), Gaps = 18/493 (3%)

Query: 18  MIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGI 77
           M IS+KL++  ++  VSV MGT  NK +L   GF      +A PND+ +A      D+  
Sbjct: 1   MGISKKLNDLPDILSVSVSMGTDMNKQILIDGGFDASSIGDAGPNDLMIA--CSFEDSVR 58

Query: 78  AQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQA 137
            + ++  LE ALK+    +   +   + R    A + + DAN+A+ISV G YAA  A +A
Sbjct: 59  EEDVLADLEAALKKQ--VTQKDRDSERPRTLTRAAEDV-DANIAVISVPGIYAAAEARKA 115

Query: 138 LDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIG 197
           L++ L+V+MFSDNV+L+DEI LK  A  KGLL+MGPDCGT    G    FAN +  G+IG
Sbjct: 116 LEKGLHVLMFSDNVSLDDEIALKDLAHGKGLLMMGPDCGTCAFQGVAFCFANAVQRGSIG 175

Query: 198 VIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLA 257
           ++ ASGTG QE    +   G G++  IG GGRDLS EVGG   L A + L ADE +  + 
Sbjct: 176 IVSASGTGAQEAAVLLDSWGMGVSQIIGTGGRDLSIEVGGRMFLDAFDALEADEGTSHIL 235

Query: 258 FVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSR 317
            +SKPP E V  K+ +    + KP VA FLG       +  ++ +  +     LA L+  
Sbjct: 236 LISKPPHETVARKVRDRAARSTKPVVACFLGDVAEDLSETVLFKSDIVSAVDALALLVDS 295

Query: 318 VTARRNAIAP-----VSSGFICGLYTGGTLAAEAAGLLAGHLGVEAD-------DTHQHG 365
             +     A          ++ GL+ GGTL  EA       L             +    
Sbjct: 296 SFSAPEESAIEIDCMPDGSYVRGLFCGGTLMEEAKMTFMSSLPDVDVYANSAKGGSISLD 355

Query: 366 MMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATA 425
              ++  H  +DLGDD +T G+PHPMIDP  RN  IA   A  +  V+LLD V+G+GA  
Sbjct: 356 DSSESRGHAFLDLGDDAFTQGKPHPMIDPQTRNARIAQEAADTETAVILLDFVLGYGAHE 415

Query: 426 DPAASLVSAWQKACAARLD-NQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPE 484
           DP  + + A  KA  + L+  + +  IA V GT+ DPQ +  Q   L   G+ V  +  +
Sbjct: 416 DPVGAALPAIHKANVSCLESGRTMVFIAYVLGTDADPQDKQHQEEMLAQEGVLVCQTNVQ 475

Query: 485 ATLLAAALIHPLS 497
           A  LAA+++  L 
Sbjct: 476 AANLAASIVKGLR 488


>UniRef50_D2L8W4 FdrA family protein n=1 Tax=Desulfovibrio sp. FW1012B
           RepID=D2L8W4_9DELT
          Length = 502

 Score =  333 bits (853), Expect = 1e-89,   Method: Composition-based stats.
 Identities = 187/493 (37%), Positives = 275/493 (55%), Gaps = 18/493 (3%)

Query: 1   MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNAT 60
           ++ A ++K  +QDSV LM ISR+ S+   V  V  ++GT +NK +L   G   D    AT
Sbjct: 2   LLQATVRKNQYQDSVRLMQISRQASQLPGVGKVLALLGTDSNKKVLADLGLMDDVVAAAT 61

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
            ND+ +       +A  A+A+   L +   +L   + +  A    +  + A  +L  AN 
Sbjct: 62  ANDLVIC-----VEAENAEAVAAALADVDGRLRSVAAAGPAEANPKSLEEAVARLSGANF 116

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           A+IS+ G+ A      AL++ L+VM+FSDN++L DE +LK  A +KGLL+MGPDCGT++I
Sbjct: 117 AMISLPGQLAKLDVVTALEQGLHVMLFSDNISLADEAELKALAAKKGLLLMGPDCGTAII 176

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            G  LA ANV+  G IG+  ASGTGIQE+   I   G G++HAIG+GGRDL +EVGG   
Sbjct: 177 NGVALALANVVRRGEIGLAAASGTGIQEVTCLIDRFGGGVSHAIGVGGRDLKKEVGGTMM 236

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
             A+ +L+AD  ++ L  +SKP A  V   +++  + +G   V   LG   A A  E + 
Sbjct: 237 RQAIRILAADPATKTLVVLSKPGAPEVMETVLDEARQSGLRVVTCLLGG-DASAAPEGMV 295

Query: 301 FASSLDEAARLACL-----LSRVTARRNAIAPVSSG--FICGLYTGGTLAAEAAGLLAGH 353
             S+L+EAA  A       L+     R   A +SSG  ++ GLY+GGTL  E   LL   
Sbjct: 296 CVSTLEEAAFAALDRDLPPLAIPPGLRERAAALSSGRQYLRGLYSGGTLCYETLFLLKDD 355

Query: 354 LGVEAD----DTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQ 409
           L ++++       + G  +    H  +DLG+D +T GRPHP+ID +LR + +A+  A P 
Sbjct: 356 LDIQSNVAIKPELKLGYPVKGTGHCCVDLGEDEFTQGRPHPIIDLSLRLERLAEEMADPS 415

Query: 410 VRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIA 469
           V+V+LLD+V+G+GA  +PAA L  A   A  AR D  P   +  V GT+ DPQ    Q  
Sbjct: 416 VKVVLLDLVLGYGAHRNPAAELAEAIAAASQARPDGGP-VVLVHVCGTQADPQDLQAQEK 474

Query: 470 TLEDAGIAVVSSL 482
            L + G  +  + 
Sbjct: 475 LLAEVGAFLFPTN 487


>UniRef50_UPI0001C165DF GCN5-related N-acetyltransferase n=2 Tax=Nostocaceae
           RepID=UPI0001C165DF
          Length = 993

 Score =  327 bits (838), Expect = 7e-88,   Method: Composition-based stats.
 Identities = 72/528 (13%), Positives = 151/528 (28%), Gaps = 65/528 (12%)

Query: 18  MIISRKLSESEN-VDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAG 76
           M +++   + +  V + S+ +       +L T        +         A+   +   G
Sbjct: 58  MALNKISQKLKGAVMEASIPLRLDKASDILRTE--KTSALDRIFAPQTV-AVIGASEKPG 114

Query: 77  IAQ-AIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAEL 133
                ++  L            +    ++  ++ + +        +LA+I+       ++
Sbjct: 115 SVGRTLLWNLITNPFNGTVFPINPHRHSVLGIKAYPTIFDISEKIDLAVIATPAPTVPKI 174

Query: 134 ANQALDRNLN-VMMFSDNV------TLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLA 186
               +   +   ++ S          +  E ++ + A+   + ++GP+C   M   + L 
Sbjct: 175 IADCVQVGIKGAIIISAGFKEAGEKGIALEKEILSVAQGGKIRIIGPNCLGMMNPISGLN 234

Query: 187 F---ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTA 243
               + +   G++G +  SG     +         G +  + LG       +  IS    
Sbjct: 235 ATFASKIAQPGSVGFLSQSGALCTSILDWSLQENVGFSAFVSLG------SMLDISWGDL 288

Query: 244 LEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFAS 303
           +  L  D  ++ +    +    A             KP + +  G T A A+       S
Sbjct: 289 IYYLGDDPHTKSIVIYMESIGNARSFLSAAREVTLTKPIIVIKAGRTAAAAKAAASHTGS 348

Query: 304 SLDEAARLACLLSRVTARR--------------NAIAPVSSGFICGLYTG---GTLAAEA 346
                A L     R    R                        +  L      G LA ++
Sbjct: 349 LAGSDAVLDAAFKRCGVLRVNSISDLFDMSEVLAKQPCPQGPRLTILTNAGGPGVLATDS 408

Query: 347 AGLLAGHLGVEADDTHQHGM---MLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIAD 403
                G L V +  T ++           +  ID+  D           DP    + +  
Sbjct: 409 LIESGGELAVISPQTMENLNHILPPQWSHNNPIDILGDA----------DPQRYTKALQI 458

Query: 404 LGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQC 463
                    LL  V++   A  DP         +        Q    +A+  G +     
Sbjct: 459 ASEDSNSDGLL--VILTPQAMTDPT-----RIAQELKPYSQMQGKPILASWMGGD----D 507

Query: 464 RSQQIATLEDAGIAVVSSLPEATLLAAALIH-PLSPAAQQHTPSLLEN 510
            ++    L   GI   S    A  + + +     +      TP L   
Sbjct: 508 IAEGKKILNLEGIPTYSYPDTAARIFSYMWRYSYNLKGIYETPVLPAL 555


>UniRef50_A6C207 Acetyl-CoA synthetase / acetyltransferase (GNAT) family protein n=2
           Tax=Planctomycetaceae RepID=A6C207_9PLAN
          Length = 899

 Score =  321 bits (823), Expect = 4e-86,   Method: Composition-based stats.
 Identities = 82/542 (15%), Positives = 164/542 (30%), Gaps = 82/542 (15%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +         + Q L            +     L +   + S        +LA+
Sbjct: 15  VAVVGASQRPLSVGQTVFQNLVSGGFSGEVYPVNPRHARLGEHPCYQSVLDLPEPVDLAV 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRARE-KGLLVMGPD 174
           I    +   ++  Q     +  ++        +     E E+Q+ + AR+  G+ ++GP+
Sbjct: 75  ICTPAQTIPDVIQQCGTAGIRGIVILSAGFRETGAAGKERELQVLSIARQFSGMRIIGPN 134

Query: 175 CGTSMIAGTPLA--FANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
           C   M     L   FA  MP  GNI  I  SG     +         G +H + +G    
Sbjct: 135 CLGIMAPYVNLNASFATDMPLTGNIAFISQSGALCTAVLDWALQEKVGFSHFVSVGN--- 191

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
              +  +     ++  + D +++ +    +   EA +           KP +A   G   
Sbjct: 192 ---MLDVGIADLIDYFALDPQTKSIILYVESITEARQFMSAARAFTKHKPIIAYKAGRFQ 248

Query: 292 AVARDENVWFASSLDEAARLACLLSRVTARR--------------NAIAPVSSGFICGLY 337
             A+  +    +     A      +R    R                  P     +  L 
Sbjct: 249 ESAKAASSHTGAMAGVDAVYEAAFARAGIVRVFELDDLFDCAELLARHRPPRGERLAILT 308

Query: 338 TG---GTLAAEAAGLLAGHLGVEADDTHQHGM----MLDADSHQIIDLGDDFYTVGRPHP 390
                G +  +A     G L   +++T +          +  + +  LGD          
Sbjct: 309 NAGGPGVMCTDALLERKGVLASLSEETIEQLNRVLPPAWSHGNPLDILGDAL-------- 360

Query: 391 MIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYA 450
              P    + +  +    QV  +L  VV+   A  DP  +  +  + A            
Sbjct: 361 ---PERFGKALEIILVDSQVDGVL--VVLSPQAMTDPTGAADAVIKAAKL-----TSKPI 410

Query: 451 IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA-QQHTP---- 505
           + +  G  +  +  ++    L  AGI   ++  +A      L+           TP    
Sbjct: 411 LTSWMGGGKVLEGITR----LTAAGIPTYNTPEQAVRAFMYLVTYARNREFLYETPRAMP 466

Query: 506 --SLLENVAVINIGLRSF------------ALELQSASKPVVHYQWSPVAGGNKKLARLL 551
              LL+   +  +   +                L++   PV     +  A    +L++ +
Sbjct: 467 LHYLLDRPHLRELADAALLEGRDILSECTSKTLLEAYGIPVNRTVVARSAEEAVQLSQQM 526

Query: 552 ER 553
            R
Sbjct: 527 GR 528


>UniRef50_B3DWI6 Acyl-CoA synthetase (ADP forming) alpha and beta chain n=1
           Tax=Methylacidiphilum infernorum V4 RepID=B3DWI6_METI4
          Length = 908

 Score =  317 bits (813), Expect = 5e-85,   Method: Composition-based stats.
 Identities = 76/511 (14%), Positives = 139/511 (27%), Gaps = 62/511 (12%)

Query: 51  FWHDDFNNATPNDICVAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQALTQVRRWD 109
                  N  P     A+   +        AIM+ L          +     +   + + 
Sbjct: 11  LGTYGLRNFLPPQRV-ALVGASEKPATVGRAIMENLIRWGGIFYPVNPYHDEIFGRKSYP 69

Query: 110 SACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTL------EDEIQLKTR 162
           +        +LA+I+       E+    +  ++   ++ S             E ++   
Sbjct: 70  NIESLPEPIDLAIIATPAPTVPEIMEGCVRASVKGAIIISAGFKEIGKSGKLLEEKVIAI 129

Query: 163 AREKGLLVMGPDCGTSMIAGTPLA---FANVMPEGNIGVIGASGTGIQELCSQIALAGEG 219
           A+  G+ V+GP+C   ++          A +   G+I  +  SG     +         G
Sbjct: 130 AKRGGVRVIGPNCVGVILPHARFNGTFLAGLPKSGHIAFLSQSGALGAAVLDWSFSQNIG 189

Query: 220 ITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATG 279
            +  + LG       +  +     L  L+ D  + V+    +   +              
Sbjct: 190 FSAFVSLG------SMADVDWGDILFFLAEDPLTRVILIYMESIGDPSSFLSAARQVNFQ 243

Query: 280 KPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRN---------------A 324
           KP + L  G +   +R       S       L     R    R                 
Sbjct: 244 KPILVLKAGRSKEGSRAALSHTGSLTGSDEVLDAAFLRTGVLRVASFSEFFSLASFFSQR 303

Query: 325 IAPVSSGFICGLYTG--GTLAAEAAGLLAGHLGVEADDTHQHGMML----DADSHQIIDL 378
             P     +     G  G LA +   +  G L    D   Q          +  + +  L
Sbjct: 304 PLPTGPRLVILTNAGGAGVLATDRLVISGGELATLTDAALQRLNAFLPLAWSHGNPVDIL 363

Query: 379 GDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKA 438
           GD            D     + +  L  +  V  +L  V++   A  DP         K 
Sbjct: 364 GD-----------ADAQRYRKALDILSEEEHVDGIL--VILTKQAMTDP-----EEVAKQ 405

Query: 439 CAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAA-LIHPLS 497
                       ++   G E       +    LE  GI       EA    +   +H  S
Sbjct: 406 VVLFARGYHKPILSCWMGGE----SVHKARLFLEQEGIPTFEFPEEAAQAFSYGWMHRKS 461

Query: 498 PAAQQHTPSLLENVAVINIGLRSFALELQSA 528
            +A   TP  +     +     + A  +  A
Sbjct: 462 LSAIYETPMPVGATEELIKAKENTAFVISQA 492


>UniRef50_D2RGD1 Acetyl coenzyme A synthetase (ADP forming), alpha domain protein
           n=3 Tax=Archaea RepID=D2RGD1_ARCPR
          Length = 663

 Score =  314 bits (804), Expect = 7e-84,   Method: Composition-based stats.
 Identities = 83/514 (16%), Positives = 173/514 (33%), Gaps = 54/514 (10%)

Query: 65  CVAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALI 123
            +A+       G     +++ L +   ++   +   + +  V  + S      + +LA+I
Sbjct: 9   AIAVIGATPKEGKVGNTLLKNLSKFKGKIYAVNPKYREVLGVECYPSVKDLPEEVDLAVI 68

Query: 124 SVAGEYAAELANQALDRNLN-VMMFSDNVTL----EDEIQLKTRAREKGLLVMGPDCGTS 178
           +V  E   ++  +  ++ +   ++ S         + E++L    ++ G+ ++GP+C   
Sbjct: 69  AVPAEVVPKVLEECGEKGVKAAVVISAGFREVGNYKLEMELVEICKKYGIKMVGPNCLGI 128

Query: 179 MIAGTPLA--FANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREV 235
           +     L   F+ V P  G I +I  SG  I  +         G +  + LG + L  E 
Sbjct: 129 INTSNGLNATFSGVEPLRGRIALISQSGALIVAIMDWALANNIGFSKIVSLGNKALLNEC 188

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVAR 295
                   +E LS D+++EV+A   +   E  R       +   KP VA+  G T A A+
Sbjct: 189 ------DFIEYLSNDDETEVIALYVEGIEEGRRFM--EIAEKCRKPIVAIKSGKTSAGAK 240

Query: 296 DENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGL-----YTGGTLAAEAAGLL 350
             +    S             +              F   L     + GG     A    
Sbjct: 241 AVSSHTGSLAGSYEACRTAFRQSGVVEAESVEELFDFSTVLSYIKGFRGGV----AIVTN 296

Query: 351 AGHLGVEADDTHQHGMM-LDADSHQIIDLGDDFYTVGRPHPMI------DPTLRNQLIAD 403
           +G   V A D  +   + L +  H+ +++       G  +  +      D     + +  
Sbjct: 297 SGGPAVMASDAVEKYNLNLASFEHETVEMLRSIAPYGNVYNPVDVLGDADAERFCKALDI 356

Query: 404 LGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQC 463
           +     V ++L   ++   AT D                        +    G     + 
Sbjct: 357 VAKDRNVGLIL--AILTPTATIDGVKVAEKIV---------GINKKVVGCFMGG----KS 401

Query: 464 RSQQIATLEDAGIAVVSSLPEATLLAAAL-IHPLSPAAQQHTPSLLENVAV---INIGLR 519
             + +  L + GIA  +    A    A++  +      ++     ++   V   +  GL 
Sbjct: 402 FEEAVRILREKGIANFNDPVRAVKAIASVQFYSRRTKRKEFVRFDVDLKKVRELLKRGL- 460

Query: 520 SFALELQSASKPVVHYQWSPVAGGNKKLARLLER 553
            +   ++    PV  Y  +  A    ++A  +  
Sbjct: 461 -YFEVVREYGIPVPPYGIARSAEEALEIADKIGY 493


>UniRef50_Q2JX06 Acetyltransferase, GNAT family n=25 Tax=Bacteria RepID=Q2JX06_SYNJA
          Length = 931

 Score =  307 bits (785), Expect = 9e-82,   Method: Composition-based stats.
 Identities = 89/521 (17%), Positives = 150/521 (28%), Gaps = 79/521 (15%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEE--ALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+       G     ++  L        +   +     +  +R ++         +LA+
Sbjct: 28  VAVVGATEREGSVGRTVLWNLISHPFGGTVYPVNPKRHQVLGIRAYERLSALPEPVDLAI 87

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNV------TLEDEIQLKTRAREKGLLVMGPDC 175
           I++       +  + ++  +   ++ S          LE E  ++  AR K L ++GP+C
Sbjct: 88  IAIPAAGVPAVIQECVEAGVKGAIVLSAGFKEIGPEGLELEKAIQEAARGK-LRLIGPNC 146

Query: 176 GTSMIAGTPLAF---ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
                  T L     A +   GN+G I  SG     +         G +  I LG     
Sbjct: 147 LGIQNPHTGLNATFAAQMARPGNVGFISQSGALCTSILDWSLQENVGFSAFISLG----- 201

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
             +  +     ++ L  D  +  +    +   +A          A  KP + +  G T A
Sbjct: 202 -SMLDVGWGDLIDYLGQDPHTHSIVLYMESVGDARSFLSAAREVALSKPIIVIKAGRTQA 260

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRNAIAP--------------VSSGFICGLYT 338
            A+       S     A L     R    R                        +  L  
Sbjct: 261 AAQAAASHTGSLTGSDAVLDAAFRRCGVLRVDHIEDLFDMAEVLAKQPRPQGPHLSILTN 320

Query: 339 G---GTLAAEAAGLLAGHLGVEADDTH----QHGMMLDADSHQIIDLGDDFYTVGRPHPM 391
               G LA +A     G L   A +T     Q      +  + I  LGD           
Sbjct: 321 AGGPGVLATDALIRAGGSLASLAPETLEQLSQILPPHWSHGNPIDVLGD----------- 369

Query: 392 IDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAI 451
             P    Q +  +   P  +  L  V++   A  DP A+     +     R        +
Sbjct: 370 AGPERFAQALEIVLRDPGSQGCL--VILTPQAMTDPTATAAKVVE---TWRRSGSRQPIL 424

Query: 452 ATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH-PLSPAAQQHTPSLLEN 510
           A+  G              L  AGI       +A  + + L     +  A   TP+L   
Sbjct: 425 ASWMGGAL----VDAGEQILNQAGIPTYRYPDQAARVFSYLWRFSDNLKALYETPTLPPA 480

Query: 511 VAV-----------------INIGLRSFALELQSASKPVVH 534
            AV                   +        L +   PVV 
Sbjct: 481 RAVERDRVHQILSQARQQGRTLLTEVESKEILAAYGIPVVP 521


>UniRef50_D0MJL0 Acetyl coenzyme A synthetase (ADP forming), alpha domain protein
           n=6 Tax=Bacteria RepID=D0MJL0_RHOM4
          Length = 929

 Score =  306 bits (784), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 81/509 (15%), Positives = 146/509 (28%), Gaps = 68/509 (13%)

Query: 36  MMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQ-AIMQQLEE--ALKQL 92
           +M    +  L        D      P    VA+   +   G     ++  L        +
Sbjct: 7   VMQHDPSHELFQPRRLQLDAI--FKPRS--VAVIGASERPGSVGRTLLWNLISNPFGGTV 62

Query: 93  AQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNV 151
              +     +  +R + S        +LA+I+        +  + ++  +   ++ S   
Sbjct: 63  YPVNPKRTNVLGIRAYPSVKDIPEPVDLAVIATPAPTVPGVVQECVEAGVKGAVIISAGF 122

Query: 152 ------TLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAF---ANVMPEGNIGVIGAS 202
                     E Q+ T AR  G+ ++GP+C   M   T L     + +   G +G I  S
Sbjct: 123 KEIGEEGRRLEEQILTIARRGGMRIIGPNCLGVMRPVTGLNATFASTMARPGTVGFISQS 182

Query: 203 GTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKP 262
           G  +  +         G +  I +G       +  +     +  L +D  ++ +    + 
Sbjct: 183 GALLTSILDWSLEENVGFSAFISIG------SMLDVGWGDLIYYLGSDPYTKSIILYMES 236

Query: 263 PAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARR 322
             +A          A  KP + +  G T   AR       S       L+    R    R
Sbjct: 237 IGDARSFLSAAREVALQKPIIVIKAGRTEEAARAALSHTGSLAGSDEVLSAAFRRTGVLR 296

Query: 323 NAIAP--------------VSSGFICGLYT---GGTLAAEAAGLLAGHLGVEADDTHQH- 364
                                   +  L      G LA +A     G L   +++T +  
Sbjct: 297 VDSIADLFYMAEVLAKQPRPEGPRLTILTNAGGAGVLATDALVQGGGQLAELSEETKKKL 356

Query: 365 ---GMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGF 421
                   +  + +  LGD            DP    + +    A      LL  V++  
Sbjct: 357 DEFLPPHWSHGNPVDILGD-----------ADPERYAKALEVTLADENSDGLL--VILTP 403

Query: 422 GATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSS 481
            A  DP              R        +A+  G        +     L  AGI     
Sbjct: 404 QAMTDPTQ------TAEQLRRFAQSRKPILASWMGG----VEVAAGKKILNRAGIPTFQY 453

Query: 482 LPEATLLAAALIH-PLSPAAQQHTPSLLE 509
              A  +   +     +  A   TPSL +
Sbjct: 454 PDTAVRVFNYMWRYSYNLRALYETPSLPD 482


>UniRef50_B8CEH1 Acetyl-coa synthetase n=1 Tax=Thalassiosira pseudonana
           RepID=B8CEH1_THAPS
          Length = 973

 Score =  302 bits (774), Expect = 2e-80,   Method: Composition-based stats.
 Identities = 74/545 (13%), Positives = 159/545 (29%), Gaps = 83/545 (15%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSS----QALTQVRRWDSACQKL---PD 117
           +A+   +   G     ++  L  +         +     + +  ++ +            
Sbjct: 53  IAVIGASDKEGSVGRTLLWNLMRSPFGGTIYPINVNPRKKNIFGIKSYTRVQDIPSSDGQ 112

Query: 118 ANLALISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLV 170
            ++A+I+V  ++  ++    ++  +   +        +     + E ++   A +  + V
Sbjct: 113 IDMAVIAVNAKHVKQVMEDCVEVGIKAAVIISAGFKETGAEGAQLEREVYEIACKGKIRV 172

Query: 171 MGPDCGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLG 227
           +GP+C   M     L       +   GN+  I  SG     +      A  G +  + +G
Sbjct: 173 VGPNCLGVMNPIVGLNATFATQIAKPGNVAFISQSGAMCTSILDWSLQANVGFSSFVSIG 232

Query: 228 GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFL 287
                  +  +S    +  L  D  ++ +A   +   +A       +  A  KP + +  
Sbjct: 233 ------SMLDVSWGDIIYYLGDDPNTKAIAIYMETIGDARSFMSAASEVAMTKPIIVIKP 286

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRN---------------AIAPVSSGF 332
           G T   A        S       L     R    R                   P     
Sbjct: 287 GRTEQAAAAAASHTGSLAGSDDVLDAAFKRCGVLRVNKIREVFEIVELLGKQPRPKGKHL 346

Query: 333 ICGLYTG--GTLAAEAAGLLAGHLGVEADDTHQHGM----MLDADSHQIIDLGDDFYTVG 386
                 G  G ++ +A     G L   +DDT +          + S+ I  LGD      
Sbjct: 347 TIVTNAGGPGVISTDALIESGGQLSWISDDTMKSLNEILPPHWSHSNPIDILGD------ 400

Query: 387 RPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQ 446
                  P    +++           +L  +V+   +  DP+A       +   AR    
Sbjct: 401 -----ATPATYAKVVEIAAQDEYSDGIL--IVLTPQSMTDPSA-TARGIAEI--ARKIGG 450

Query: 447 PLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH-PLSPAAQQHTP 505
               +A+  G     +   +  A L++AGI        A  + + +    ++ +    TP
Sbjct: 451 RKPILASWMGG----KGVEEGRAILDEAGIPTYDYPDSAAEMFSYMYKYSVNLSQLYETP 506

Query: 506 SLLENVAVINIGLRSF-----------------ALELQSASKPVVHYQWSPVAGGNKKLA 548
                +   ++ + +                     L +   P V    +  A      A
Sbjct: 507 RWCAEMHPESLKVDTIIAEAQSSGRTILTELESKQLLSAYGIPTVTTILACTAEEAALAA 566

Query: 549 RLLER 553
             +  
Sbjct: 567 DGVGY 571


>UniRef50_D2R7V1 CoA-binding domain protein n=1 Tax=Pirellula staleyi DSM 6068
           RepID=D2R7V1_9PLAN
          Length = 911

 Score =  300 bits (768), Expect = 8e-80,   Method: Composition-based stats.
 Identities = 84/543 (15%), Positives = 161/543 (29%), Gaps = 82/543 (15%)

Query: 65  CVAIRSEAADAGIA-QAIMQQLEEALKQLAQGSGSS--QALTQVRRWDSACQKLPDANLA 121
            VA+   +   G     +++ L E          ++    +  +  +    Q     +L 
Sbjct: 14  VVAVVGASDQPGKVGHTLLKNLVEHGYTGRVYPINATRDTVQGMTAYRDLVQLPEKPDLV 73

Query: 122 LISVAGEYAAELANQALDRNL-NVMMFSDNV------TLEDEIQLKTRAREK-GLLVMGP 173
           +I        +L  Q     +  V++ S          ++ E Q++   +   GL V+GP
Sbjct: 74  VICTPSTTVPKLIEQCGQLGIMGVVIISAGFREVGPAGMQLEQQIREIQKSYPGLRVLGP 133

Query: 174 DCGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
           +C   ++    L+ +    +   G +  +  SG     +      AG G +H + LG   
Sbjct: 134 NCLGFLVPDLKLSASFARGMPKPGRLAFLSQSGALCTAVLDWALDAGIGFSHFVSLGN-- 191

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
               +  +     L+ L+AD  ++ +    +  + A          A+ KP VA   G  
Sbjct: 192 ----MLDVGLDDMLDYLAADPTTDAVILYVESISRAREFMSAARAFASHKPIVAYKAGRF 247

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARRN---------AIAPVSSGFICGLYTG-- 339
              A+  +    +     A       R    R          A          G   G  
Sbjct: 248 SDSAKAASSHTGAMAGVDAVYEAAFQRAGIVRVFDVDDMFDCAELLSRRKMPRGARLGII 307

Query: 340 ------GTLAAEAAGLLAGHLGVEADDTHQHGM----MLDADSHQIIDLGDDFYTVGRPH 389
                 G +A +A     G +      T +          +  + I  LGD   +     
Sbjct: 308 TNAGGPGVMACDALLARHGQIATLTPATIEKLNSVLPPFWSHGNPIDVLGDAPASR---- 363

Query: 390 PMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLY 449
                    + +  + A PQV  +L  V++      DP      A  +A A         
Sbjct: 364 -------YAESLGAVLADPQVDTVL--VILTPQDMTDP-----EATARAVAEVAGRSSKP 409

Query: 450 AIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQ-QHTPSLL 508
            +A   G        +  +  L  AG+   ++   A      L+           TP  +
Sbjct: 410 VLAAWMGRGM----VASGVKILGAAGVPTYNTPEHAIRAFMHLVAYAKRREVLYETPRDV 465

Query: 509 ENVAVIN------------------IGLRSFALELQSASKPVVHYQWSPVAGGNKKLARL 550
                ++                  +   +    L++   PV     +  A    ++AR 
Sbjct: 466 PLTFSLDRPTLHARAEQILKSSDGVLTENASKDLLETYGIPVTKPIAASTAAQAVEVARQ 525

Query: 551 LER 553
           L  
Sbjct: 526 LGY 528


>UniRef50_Q2LUQ3 Acetyl-CoA synthetase / acetyltransferase (GNAT) family protein n=4
           Tax=Bacteria RepID=Q2LUQ3_SYNAS
          Length = 918

 Score =  296 bits (758), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 67/490 (13%), Positives = 135/490 (27%), Gaps = 64/490 (13%)

Query: 57  NNATPNDICVAIRSEAADAGIAQAIM--QQLEEALKQLAQGSGSSQALTQVRRWDSACQK 114
           N   P    VA+   +   G    I+    L+   +++   +   + +   + +++    
Sbjct: 21  NVFNPGS--VALIGASDREGSVGRIIFTNLLQAKDRKIFPVNPKKKVILGRKCFENIADI 78

Query: 115 LPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNV------TLEDEIQLKTRAREKG 167
               +LA+I+   +   EL        +  +++ S             E ++    ++ G
Sbjct: 79  SEPVDLAVIATPAKEVPELVEDCGRAGIGGLVIISAGFKEIGEEGRLLEERITASRKKYG 138

Query: 168 LLVMGPDCGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           + ++GP+C   +     L         P G+I  I  SG     +         G +   
Sbjct: 139 MRILGPNCLGFVRPNEGLNATFLKTNPPPGHIAFISQSGALGSAILDWAVNEHVGFSMFA 198

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
            LG       +  +     ++ L  D  +  +    +    A +        A  KP + 
Sbjct: 199 SLG------AMSDVDFGDLIDFLGEDPDTRSILLYMEGVGNAKKFMSAARAFAMRKPIIV 252

Query: 285 LFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRN---------------AIAPVS 329
           +  G     A+       +   + A       R    R                   P  
Sbjct: 253 IKPGRFTESAQAARSHTGAMAGDDAIYEAAFKRAGVLRVKEIADLFDCAEILDSRKLPKG 312

Query: 330 SGFICGLYTG--GTLAAEAAGLLAGHLGVEADDTHQHGM----MLDADSHQIIDLGDDFY 383
                    G  G +A +A   L G L   +D++ +          +  + I  LGD   
Sbjct: 313 PRLAIVTAAGGPGVMATDALIELGGELARLSDESMERLNSILPPFWSKGNPIDLLGD--- 369

Query: 384 TVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARL 443
                    D +   Q          V  +L+  V    A  D          +A     
Sbjct: 370 --------ADASRYAQAAQICLNDSGVDGVLVIYVPMDTAVPD-------EVAQAVIDTA 414

Query: 444 DNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHP-LSPAAQQ 502
                  +    G ++      +    L    I    +  +A      +    ++     
Sbjct: 415 KGSWKPILTAFMGADKVRSALEK----LARNNIPNYETPEQAVRAYVNMYQDEINLELLY 470

Query: 503 HTPSLLENVA 512
            TP  L    
Sbjct: 471 ETPEELPGRE 480


>UniRef50_D1A7Z1 FdrA family protein n=2 Tax=Actinomycetales RepID=D1A7Z1_THECD
          Length = 480

 Score =  293 bits (749), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 175/480 (36%), Positives = 241/480 (50%), Gaps = 26/480 (5%)

Query: 4   AFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPND 63
             ++ G ++DSV+L+ +SR+L+  E +    V M T  N  LL   GF   +   A P+D
Sbjct: 5   VEVQSGRYRDSVTLLRVSRELAGREGITAAMVAMATEPNLDLLRRRGFAVPE--GAGPDD 62

Query: 64  ICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKL---PDANL 120
           + VAIR    D    +   + LE  L      +          R   A  +L   P   L
Sbjct: 63  LVVAIRGA--DEASVREARRVLEGLLADDPAPAARHAPQDDPPRTTGAAARLLAEPAGGL 120

Query: 121 ALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           AL+SV G YA   A  AL+  LNVM+ S +V L  E+ LK  A  +GL+VMGP CGT++I
Sbjct: 121 ALVSVPGRYAFIEAMDALNAGLNVMVCSGDVPLHQEVALKEAAGRRGLIVMGPGCGTAVI 180

Query: 181 AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            G  L FAN +  G + ++ ASGTG Q++   +  AG G+ H +G+GGRDLS EV G S 
Sbjct: 181 GGAGLGFANAVRPGPVSIVAASGTGAQQVMCLLDAAGVGVRHVLGVGGRDLSAEVSGRST 240

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPT-VALFLGYTPAVARDENV 299
           L AL  L  D  +E++A V+ PPA  V   + +A +    P   A+    +P +      
Sbjct: 241 LAALAALDEDPATELIAVVAGPPAPRVADLVHSAARRLDTPVHFAMLAEDSPDLTAATER 300

Query: 300 WFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEAD 359
             ++      R  C  +   A      PV+ G + GL+TGG L AEAA +    LG    
Sbjct: 301 LLSALGRRVPRWPCWPAARPA-----GPVAPGALRGLFTGGALRAEAALIARRMLGP--- 352

Query: 360 DTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVI 419
                   L    H++IDLG D    GR HPMIDP  R + +A   A P  RV+LLDV++
Sbjct: 353 -------DLACGGHRLIDLGADACARGRAHPMIDPAPRLEHLAAAAADPSCRVVLLDVLL 405

Query: 420 GFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVV 479
           G GA  DPAA L  A + A A R D   L  + ++ GT  DPQ   +Q A L+ AG  V 
Sbjct: 406 GQGADPDPAALLAPAIEAALAGRDD---LRVVVSLCGTPADPQGLGRQAAALQRAGADVF 462


>UniRef50_A1SGR4 FdrA family protein n=1 Tax=Nocardioides sp. JS614
           RepID=A1SGR4_NOCSJ
          Length = 471

 Score =  290 bits (742), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 181/496 (36%), Positives = 250/496 (50%), Gaps = 33/496 (6%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
           H  ++ G + DSV+L+ +SR +     V    V M TP N  +L  TG   +    A PN
Sbjct: 8   HVELRPGAYADSVTLLQVSRVVQGLPGVLAAQVAMATPLNVEVL--TGMGFEVPAQAGPN 65

Query: 63  DICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           D+ VA+      A    A +  +++AL+   +    +  +   R   SA ++ PDA +AL
Sbjct: 66  DLVVAL--RLEAADALPAALAGVDQALRDANRRDEGAATIAPPRTTASALRRTPDA-VAL 122

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG 182
           +SV G +A   A  A++   +VM+FSDNV LE E+ LK  A E+G+LVMGPDCGT+++ G
Sbjct: 123 VSVPGAHAFVEAMDAVEAGRDVMVFSDNVPLEQELALKRAAAERGVLVMGPDCGTAVVDG 182

Query: 183 TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALT 242
             L FANV+  G +G++ ASGTG Q+L + +  AG G+T A+G+GGRDLS EV G++   
Sbjct: 183 VGLGFANVVEPGPVGIVAASGTGCQQLLALLDHAGVGVTSALGVGGRDLSAEVRGLATRE 242

Query: 243 ALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFA 302
           AL  L  D   E++  +SKPPA  V  +I     A   P     LG              
Sbjct: 243 ALRRLDEDPGVELIVLISKPPAADVTAEIEAYAAALATPVELALLGPGRPDLTAAAEAVL 302

Query: 303 SSLDEAARLACLLSRVTARRNAIAP-VSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDT 361
             L         +         ++P V+ G + GL+ GGTLA+EAA +    LG      
Sbjct: 303 RRLGR------EVPAWPVDPPDVSPRVNPGALRGLFVGGTLASEAALVAGELLG------ 350

Query: 362 HQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGF 421
                  +AD H  +D GDD YT GR HPMIDP++R + +A   A P   VLLLDVV+G 
Sbjct: 351 -------EADGHTFVDFGDDEYTTGRAHPMIDPSIRLEHLARAAADPTTGVLLLDVVLGH 403

Query: 422 GATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSS 481
           GA  DPAASL  A        +             T  DPQ R +Q+  L DAG  V  S
Sbjct: 404 GAEPDPAASLAPALAGVAQPVVVAVVG--------TAGDPQGRDRQVRALVDAGAEVHLS 455

Query: 482 LPEATLLAAALIHPLS 497
              AT  A  L+    
Sbjct: 456 NAGATRRAIELLGGTR 471


>UniRef50_B5JNQ5 Acetyltransferase, GNAT family n=1 Tax=Verrucomicrobiae bacterium
           DG1235 RepID=B5JNQ5_9BACT
          Length = 892

 Score =  287 bits (734), Expect = 9e-76,   Method: Composition-based stats.
 Identities = 71/514 (13%), Positives = 138/514 (26%), Gaps = 72/514 (14%)

Query: 62  NDICVAIRSEAADAGIAQAI-MQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDA 118
           N   +A+    +  G      +  +  +  +      +  S+++  ++ +    +     
Sbjct: 12  NPQSIAVVGATSKQGTVGRAFISNMVGSKYEGAVYPVNPKSRSMMGMKVYPKLSKIPDPI 71

Query: 119 NLALISVAGEYAAELANQALDRNLNVMMF-SDNV------TLEDEIQLKTRAREKGLLVM 171
           +LA+I+        L  +     +   +  S               Q+   A++  + ++
Sbjct: 72  DLAIIATPPASVPALIEECGKCGIGAAVIVSAGFQEIGKKGEVLLRQVIRNAKKAKVRLI 131

Query: 172 GPDCGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
           GP+C   +     L  +    +   G +  I  SG     +         G +H I +G 
Sbjct: 132 GPNCLGFIRPPIGLNASFSSAMALPGRLAFISQSGALCTAVLDWSIRENVGFSHFISIG- 190

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG 288
                 +  I     ++ L  D  +  +    +   +A R    +      KP V L +G
Sbjct: 191 -----SMADIGYHDLIDYLGQDPNTSSILIYMESIKDARRFISASRSIGKTKPIVVLKVG 245

Query: 289 YTPAVARDENVWFASSLDEAARLACLLSRVTARRN---------------AIAPVSSGFI 333
            +   A   +    S   +      L  R    R                   P +   +
Sbjct: 246 RSSEGAAAVSSHTGSLSGDDTLYEALFKRSGIARVDTVKELFNIAQNLSTQSLPQNDRLL 305

Query: 334 CGLYTG--GTLAAEAAGLLAGHLGVEADDTHQHGM----MLDADSHQIIDLGDDFYTVGR 387
                G  G LA +A     G +   +  T            +  + +  LGD   +   
Sbjct: 306 IITNAGGPGILATDAHIKFNGQMASLSRSTIDKLNQVLPPAWSHGNPVDILGDSGVSR-- 363

Query: 388 PHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQP 447
                      Q       +     +L  VV+   A  +          K   A      
Sbjct: 364 ---------YKQAFEICLQEENADGIL--VVLTPQAMTN-----AYQIGKEIGALAKTTG 407

Query: 448 LYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEAT----------LLAAALIHPLS 497
              +A+  G         +    LE+ G+ V  S  EA                L     
Sbjct: 408 KTVLASFMGAAE----VERGTRVLEEMGVPVYDSPEEAVHCFNTMASYSRNQRLLAETPD 463

Query: 498 PAAQQHTPSLLENVAVINIGLRSFALELQSASKP 531
                  P   +  A+I     S    L      
Sbjct: 464 STPTDFKPHPNQARAIIKKAADSGRNILSEYEAK 497


>UniRef50_Q2Y4P6 Probable acetyl-CoA synthetase n=1 Tax=uncultured archaeon
           RepID=Q2Y4P6_9ARCH
          Length = 895

 Score =  285 bits (730), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 66/455 (14%), Positives = 140/455 (30%), Gaps = 59/455 (12%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   +   G     ++  L     +      +    ++  +  + S  Q     +LA+
Sbjct: 15  IAVIGASNTKGSVGYMLLHNLIGVGYEGVVYPVNNRRSSVQGIHAYGSISQIPARIDLAI 74

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNV------TLEDEIQLKTRAREKGLLVMGPDC 175
           I+V   +  ++  +     +  V++ S           + E ++   AR  G+ ++GP+C
Sbjct: 75  IAVPATHVPDILEECGVAGVGGVIIISAGFKEIGKEGRKLEERIGKIARRYGIRIIGPNC 134

Query: 176 GTSMIAGTPLA--FANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
              ++    L   FA++MPE G++  I  SG     +    A    G +  + +G     
Sbjct: 135 LGIIMPRFSLNASFAHLMPEHGSVAFISQSGALCTAVLDMCAHRHIGFSAFVSIG----- 189

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
             +  +     ++    D  +  +    +   +           A  KP + +  G    
Sbjct: 190 -SMLDVDFGDLIDYFGMDPATGSIMLYIESLKDVREFMSAARHFAKNKPIIVVKSGRFAR 248

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARR---------------NAIAPVSSGFICGLY 337
            A+       +   +         R  A R                   P          
Sbjct: 249 SAKAAASHTGALAGDDNFYDAAFKRAGAIRVLEIEDLFDCSAALAVQTRPHGPRLAIITN 308

Query: 338 TG--GTLAAEAAGLLAGHLGVEADDTHQH----GMMLDADSHQIIDLGDDFYTVGRPHPM 391
            G  G LAA+      G +   +D+T +          +  + +  LGD           
Sbjct: 309 AGGPGVLAADRLIDKGGVIAELSDETVEALDKVLPPFWSRENPVDVLGD----------- 357

Query: 392 IDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAI 451
             P      +  L     V  ++  V++   A  DP  +      +  +  + +     +
Sbjct: 358 ATPERYRDAVTYLLQDKNVDGII--VLLTPQAMTDPDGA-AKLVSEVASGNMPHY-KPLL 413

Query: 452 ATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEAT 486
           A+  G +            LE  GI    +  +A 
Sbjct: 414 ASWMGADA----VESGRGILERNGIPNFETPEQAV 444


>UniRef50_B6AEK9 Acetyl-CoA synthetase, putative n=1 Tax=Cryptosporidium muris RN66
           RepID=B6AEK9_9CRYT
          Length = 966

 Score =  284 bits (727), Expect = 5e-75,   Method: Composition-based stats.
 Identities = 66/509 (12%), Positives = 145/509 (28%), Gaps = 74/509 (14%)

Query: 66  VAIRSEAADAGIAQAIM------------QQLEEALKQLAQGSGSSQALTQVRRWDSACQ 113
           +A+             +             +       +   + + +     + +DS   
Sbjct: 30  IALVGATERKFSVGRALFLNMIQQHLEDVVENSHFNYTVYPVNPTRKECFGKKCYDSLLN 89

Query: 114 KLPDANLALISVAGEYAAELANQALDRNLNVM-MFSDNV------TLEDEIQLKTRAREK 166
                +L +I    +    +  +A  + +  + + S          ++ E  +   A++ 
Sbjct: 90  IPVVIDLVVIVTPAKTVLGIVQEAAKKKVPAILIISSGFKESGPEGIDREKAILDIAKKN 149

Query: 167 GLLVMGPDCGTSMIAGTPLA--FANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHA 223
           G+ ++GP+C   M     L   F N M   G    +  SG     +         G +  
Sbjct: 150 GIRILGPNCLGFMNVAYNLNATFINCMACRGTTAFLSQSGALCAAVLDWAVKVRIGFSAF 209

Query: 224 IGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTV 283
           + +G       +  I     ++ L  D  ++++    +    A +        A  KP +
Sbjct: 210 VSVG------SMSDIDWGDLVDYLGHDPNTKIILMYIESIGNARKFLSAAKEIAISKPII 263

Query: 284 ALFLGYTPAVARDENVWFASSLDEAARLACLLSRVT---------------ARRNAIAPV 328
            +  G + A  +       S +         + R+                       P 
Sbjct: 264 VIKAGKSRAAYKAAASHTGSLVGNYDAFISAMKRIGVLVVDTIEELFNCALVLNKMPHPK 323

Query: 329 SSGFICGLYTGG--TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSH---QIIDLGDDFY 383
               +     GG   +AA+A  +  G L +  +        + +        +D+  D  
Sbjct: 324 GPKLLILTNAGGPAVIAADALDISGGELSILPNSIIDRIDQIASPGWSKCNPVDILGDAT 383

Query: 384 TVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADP---AASLVSAWQKACA 440
                +           I  +    +V   LL +++      +P   A  ++    K   
Sbjct: 384 PQDYVN-----------ILKILGDEEVGDGLL-IILSPQDITNPTQVAELIIPIINKIKE 431

Query: 441 ARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATL-LAAALIHPLSPA 499
                  +  I +  G        +     L  AGI  +S+   A    A    H     
Sbjct: 432 ------KIPVICSWMGA----NEVAMGQEILVKAGIPEISNPDTAAQTFALIWCHAKHLR 481

Query: 500 AQQHTPSLLENVAVINIGLRSFALELQSA 528
               TP L +   ++     +    ++SA
Sbjct: 482 EVYETPHLEDVKTLLPKAKETALSLIESA 510


>UniRef50_Q47CI3 GCN5-related N-acetyltransferase:CoA-binding n=9 Tax=Proteobacteria
           RepID=Q47CI3_DECAR
          Length = 905

 Score =  283 bits (723), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 75/511 (14%), Positives = 138/511 (27%), Gaps = 70/511 (13%)

Query: 66  VAIRSEAADAGIAQAIM-QQLEEALKQLAQG--SGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +        I+ + +  +  +      +   + +   + + S  +      +A+
Sbjct: 16  VAVIGASDRENSVGNIIFKNILSSGYKGRLYAINPKHETIQGQQAYKSIEEIGARVEMAV 75

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLE------DEIQLKTRAREKGLLVMGPDC 175
           I+   +   +L  Q     +  V++ +   +         E ++   AR   + ++GP+C
Sbjct: 76  IATRPQTVPQLIEQCGRSGVRNVIVIASGFSEAGHIGAALERKVLEIARSYNVRILGPNC 135

Query: 176 GTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
              +     L           GN+ ++  SG     +         G +  I +G     
Sbjct: 136 LGIIRPDLGLNATFSKTTAAPGNLALVSQSGAMCSAVLDWAKSNQVGFSSVISIG----- 190

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                +     L+ L  D ++  +    +    + R        A  KP + L  G   A
Sbjct: 191 -MTADVDFGEILDYLIYDSRTHYILMYVEGIRNSRRFMSALRSAARIKPIILLKAGRHEA 249

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRNAIAP--------------VSSGFICGLYT 338
            A         +    +     + R    R                        +  +  
Sbjct: 250 GAMATATHSGMAAVSDSVFDAAVRRAGVVRVQNVGQLFYAAKALASKFRPLGNRLAIITN 309

Query: 339 GGTLAAEAAGLLAGHLGVEADDT------HQHGMMLDADSHQIIDLGDDFYTVGRPHPMI 392
           GG   A AA          A+ +          M  +      ID+G D           
Sbjct: 310 GGGPGAMAADRAGDMGIPLAELSNETMAVLNKAMPTNWSHSNPIDIGGDAT--------- 360

Query: 393 DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIA 452
            P    + I  +   P V   L  V++   A  DP      A  +A     D      I 
Sbjct: 361 -PERYREAIMAVTNDPNVDSTL--VMLSPQAMTDPL-----AVAQAIVEVADKLNRSIIC 412

Query: 453 TVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLS----------PAAQQ 502
              G E       +    LED+GI        A  L   +               P  Q 
Sbjct: 413 CWMGEE----QVREGRKLLEDSGIPAFRMPETAIELFHHISKYYRNQKLLLQTPEPTRQY 468

Query: 503 HTPSLLENVAVINIGLRSFALELQSASKPVV 533
             P       +I   L      L       +
Sbjct: 469 GRPETEGAKMLIEALLAERRKVLSEMESKAI 499


>UniRef50_Q9NAT4 Acetyl-CoA synthetase n=3 Tax=Entamoeba RepID=Q9NAT4_ENTHI
          Length = 713

 Score =  276 bits (705), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 67/473 (14%), Positives = 150/473 (31%), Gaps = 62/473 (13%)

Query: 62  NDICVAIRSEAA-DAGIAQAIMQQLEEALKQLAQGSGSSQ-ALTQVRRWDSACQKLPDAN 119
           N   V +   +     +  A+M  + +   +        +  L   + +    +     +
Sbjct: 8   NPKSVPVIGASDRKESVGYAVMNNMIKGGYKGNLYPVGRKPELFGKKCYAKIGKIEEKVD 67

Query: 120 LALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDE------IQLKTRAREKGLLVMG 172
           LA+I++  ++   +  +  +  +  +++ +       E      I+++   ++  + ++G
Sbjct: 68  LAVIAIPAKFVPGVCIECGEAGVKGLIIITAGFAEAGEEGKKMCIEIQATCQKYNMRMIG 127

Query: 173 PDCGTSMIA--GTPLAFANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
           P+C   +    G   +FA+VMP  G +  I  SG     +    A    G ++ + +G  
Sbjct: 128 PNCLGIINPRDGVNASFASVMPEAGGVAFISQSGALCTAILDWAANQHVGFSYFVSIG-- 185

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
                          E  + D K   +    +   +A +  +     A  KP + L  G 
Sbjct: 186 ----SSIDTDYADLFEFFAKDPKVTSILMYIESIKDAKKFVLRAREFAADKPIILLKAGK 241

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARRN---------------AIAPVSSGFIC 334
           +   A        S     A    +  R    R                   P ++    
Sbjct: 242 SSEGAAAAMSHTGSLAGNDAVYDAVFDRCGCIRVDSICDLWDCAHVLATQNIPQNNRLCI 301

Query: 335 GLYTG--GTLAAEAAGLLAGHLGVEADDTHQHGM----MLDADSHQIIDLGDDFYTVGRP 388
               G  G ++ +    + GHL   ++ T            + S+ +  LGD        
Sbjct: 302 ITNAGGPGVISTDRLVSVHGHLAKLSESTMNELNAFLSPFWSHSNPVDVLGDATA----- 356

Query: 389 HPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPL 448
                  +  + +  +   PQ+  ++  VV+   A  DP A +  +  +    +  + P 
Sbjct: 357 ------GVYQKTLDIVIKDPQIDGVV--VVLTPQAMTDPVA-VAKSLVEHGPYQNQSLPH 407

Query: 449 YAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQ 501
             +          Q     +  LE+  I    +   A      ++     AA+
Sbjct: 408 GWV---------NQKSEAGVKILEEGKIPNFETPERAVTAFGYIMRHPDIAAK 451


>UniRef50_Q58010 Uncharacterized protein MJ0590 n=11 Tax=Methanococcales
           RepID=Y590_METJA
          Length = 704

 Score =  276 bits (705), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 84/524 (16%), Positives = 167/524 (31%), Gaps = 50/524 (9%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
           VAI   +   G    AIM+ L++   ++   +     +  ++ + S      D +LA+I 
Sbjct: 17  VAIIGASKTEGKVGYAIMKNLKDFNGKIYPINPKYDEIFGIKCYKSVLDVEDDIDLAVIV 76

Query: 125 VAGEYAAELANQALDRNLN-VMMFSDNVTL----EDEIQLKTRAREKGLLVMGPDCGTSM 179
           V      ++  +   + +   ++ +   +     E E ++K  A+   + ++GP+C   M
Sbjct: 77  VPNIVVPKVLEECGKKGVKGAVIITAGFSEVGNYELENKIKEIAKRYNIRIIGPNCLGIM 136

Query: 180 IAGTPLA--FANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVG 236
                L   FA V P  G + +I  SG  +  +     L   G +  + +G +       
Sbjct: 137 NTHINLNATFAKVFPPKGGVSIISQSGAVLNAILDIAPLLNIGFSKVVSIGNK------A 190

Query: 237 GISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARD 296
            I     LE    DE ++++    +   +      V    +  KP +AL  G T    + 
Sbjct: 191 DIQESDLLEYFLDDEDTKIVVLYIEGLKDKR-FLKVAKKLSKKKPIIALKSGRTEVGKKA 249

Query: 297 ENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLL--AGHL 354
                 S   E              R          I    T  T+++   G++  AG  
Sbjct: 250 AKSHTGSLAGEDVIYEAAFKEAGIIRAYTFEELVDLIHLFSTQPTISSNEIGIITNAGGF 309

Query: 355 GVEADDT-----HQHGMMLDADSHQIIDLGDDFYTVGRPHPMID---PTLRNQLIADLGA 406
           GV A D+      +      +   ++ ++      +  P  +I    P    ++I  L  
Sbjct: 310 GVLAADSCVDYNMKLSNFEKSTIEKLKNILPPTANISNPLDIIGDATPERYKKVIEVLAE 369

Query: 407 KPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQ 466
              V+ LL  V++       P   +  +  +   +  + +    I +  G          
Sbjct: 370 DSNVKGLL--VILTPQEMTKPL-EVAKSIIEVKNSHKEFKNKPLITSFVGG----VSVKG 422

Query: 467 QIATLEDAGIAVVSSLPEATLLAAALIH------------PLSPAAQQHTPSLLENVAVI 514
             + L   GI    +        + L               L    ++      EN  +I
Sbjct: 423 AKSYLRKNGIPAYITPENGVKALSHLYKYSLMKVKEDYDEYLENIKEEFIKITEENKEII 482

Query: 515 -----NIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLER 553
                N    +    L     PV     +       +  + L +
Sbjct: 483 KELLSNPNEYTAKKLLSIYGLPVPKGYLAKNEDEALEYCKKLGK 526


>UniRef50_Q3SEU0 Long-chain fatty-acid-CoA ligase n=4 Tax=Proteobacteria
           RepID=Q3SEU0_THIDA
          Length = 892

 Score =  274 bits (701), Expect = 5e-72,   Method: Composition-based stats.
 Identities = 74/478 (15%), Positives = 139/478 (29%), Gaps = 55/478 (11%)

Query: 62  NDICVAIRSEAADA-GIAQAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDA 118
           N   VA+   +     +A  + + L  A  +      +     +   R +  A +     
Sbjct: 11  NASSVAVFGASEREDSVAGTLFRNLRHAGYKGEVYPINPKHAEIFGERCYARASELPATP 70

Query: 119 NLALISVAGEYAAELANQALDRNLN-VMMFSDNVTL------EDEIQLKTRAREKGLLVM 171
            LALI+      A +  +   R +   ++ S           E E  L+  A++ G+  +
Sbjct: 71  ELALIATPATTVAAILEECGQRGIRHAIVLSAGFAETGTQGIELEAGLQRVAKQHGIRFI 130

Query: 172 GPDCGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
           GP+C         L           G++ ++  SG     +       G G +  +  G 
Sbjct: 131 GPNCLGIQRPAIGLNATFSQGATQAGDLALVSQSGALCTAMLDWAEANGIGFSSVVSTG- 189

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG 288
                    +     L+ L+ D +++ +    +   +A R        +  KP V + +G
Sbjct: 190 -----ASADLDFGEILDYLAYDRQTKGILLYIEGIRDARRFMSALRATSRFKPIVMVKVG 244

Query: 289 YTPAVARDENVWFASSLDEAARLACLLSRVTARR----------NAIAP----VSSGFIC 334
              A +R       + +   A    L+ R    R                    S   + 
Sbjct: 245 RHEAGSRAVQSHTGALVGSDAVFDALVRRAGVVRVNTILQLFASARALATHIQPSGNRLA 304

Query: 335 GLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID- 393
            +  GG     A  L        A+ +      LDA       +    ++ G P  +I  
Sbjct: 305 IVTNGGGPGVMATDLAVDVGLRMAELSPATIAELDA-------VLPATWSRGNPLDIIGD 357

Query: 394 --PTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAI 451
                    +        V  +L  V++   A   P      A   A        P   +
Sbjct: 358 ATAERYRAAVGACLHDNNVDGVL--VMLTPQAMTRPT-----AVADAVIDVAKQAPKPVL 410

Query: 452 ATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH-PLSPAAQQHTPSLL 508
               G         +     + AGI   ++   A  + + L     +      TP  L
Sbjct: 411 TCWMGEA----QVHEGRQRFKQAGIPYFTTPEPAVEVFSFLAAFYENQRQLMQTPGPL 464


>UniRef50_D2S3V1 FdrA family protein n=8 Tax=Bacteria RepID=D2S3V1_9ACTO
          Length = 490

 Score =  270 bits (689), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 183/501 (36%), Positives = 258/501 (51%), Gaps = 24/501 (4%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
           H  ++ G + DSV LM +SR +S  E V  V V M TP N  L    G        A+P+
Sbjct: 8   HVSLRSGVYADSVRLMQVSRDVSAREGVTAVLVAMATPLNLEL--AAGMGLAPAEGASPD 65

Query: 63  DICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
            + VA+ +   DA  A         A ++ A G   +  L  V     A      A LA+
Sbjct: 66  QLLVAVSAVDDDALAAAVAAVDAALAARERAAGPAQTVPLRTVGAGLGALDGDGPA-LAV 124

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG 182
           +SV G+YA   A  A+    +V++FSD V +E E+ LK  A + G+LVMG DCGT++++G
Sbjct: 125 VSVPGQYAVAEAADAIAAGRSVLVFSDGVPVEHEVALKRAAHDAGVLVMGSDCGTAIVSG 184

Query: 183 TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALT 242
             L FANV+  G +G++ ASGTG Q++   +  AG G++H +G+GGRDLS  VGG++ L 
Sbjct: 185 LALGFANVVRRGPVGLVAASGTGAQQVSCLLDTAGVGVSHVLGVGGRDLSEAVGGLATLD 244

Query: 243 ALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFA 302
           AL +  AD  +E +  VSKPPA AV + +  A      P         PA    E+    
Sbjct: 245 ALALFDADPATERVLLVSKPPAPAVAVAVAEAAAELSVPV-------HPAALSAESPDLT 297

Query: 303 SSLDEAA-RLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDT 361
           ++++     +   +    +R  A+       + GL+ GGTLA EA  + A  LG    +T
Sbjct: 298 AAVEALLRDMGVAVPEWPSRPAALGAAPGAVLKGLFAGGTLADEAMLIAAPVLGDVRSNT 357

Query: 362 H-----QHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLD 416
                   G  L A  H ++D GDD  TVGR HPMIDPTLR + +A + A  +  V+L+D
Sbjct: 358 PLRPELDLGTDLVARGHVVVDFGDDALTVGRAHPMIDPTLRLEALARIAASGEPAVVLMD 417

Query: 417 VVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGI 476
           VV+G GA  DP ASLV A + A         L A+  + GTE DPQ  S+Q   L  AG 
Sbjct: 418 VVLGHGADPDPVASLVPALRAA--------GLPAVVALVGTEADPQGWSRQADALAAAGA 469

Query: 477 AVVSSLPEATLLAAALIHPLS 497
           AV +S  +AT  A  L+    
Sbjct: 470 AVFASNAQATRHALDLLGAAR 490


>UniRef50_C5A641 Acetyl-CoA synthetase (ADP forming), alpha chain (AcdA) n=18
           Tax=Euryarchaeota RepID=C5A641_THEGJ
          Length = 463

 Score =  270 bits (689), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 70/461 (15%), Positives = 139/461 (30%), Gaps = 41/461 (8%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQALT------QVRRWDSACQKLPDA 118
           +A+   +   G    AIM+ L E   +      + + +         + + S      + 
Sbjct: 15  IAVIGASEKPGKIGYAIMKNLVEYGYEGKIYPVNIKGVEIKIGNRVFKSYKSILDVPDEV 74

Query: 119 NLALISVAGEYAAELANQALDRNLNVM-MFSDNVTL------EDEIQLKTRAREKGLLVM 171
           ++A+I V  ++  ++  +   + + V+ + S           + E QL   A + G+ ++
Sbjct: 75  DMAVIVVPAKFVPQVVEECGKKGVKVLPIISSGFGELGPEGKKIEQQLVETAHKYGMRIL 134

Query: 172 GPDCGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
           GP+    +     L        +  G + +I  SG     L     L   G++  + +G 
Sbjct: 135 GPNIFGVVYTPEKLNATFGPTDVMPGKLALISQSGALGIALMGWTILEKVGLSAVVSIGN 194

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG 288
           +        I     LE    DE ++ +    +   +  R   V    +  KP V +  G
Sbjct: 195 K------SDIDDADLLEYFETDENTKAILIYMEGVKDGRRFMEVAKKVSKVKPIVIIKAG 248

Query: 289 YTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAG 348
            +   A+       S             +    R      +  +   L      A E   
Sbjct: 249 RSERGAKAAASHTGSLAGSDKIYDAAFKQAGIIRALTIGEAFDYARTLSNLPEPAGENLV 308

Query: 349 LLAGHLGV---EADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID------PTLRNQ 399
           +L    G+     D   + G+ L  D  ++    +     G     +D            
Sbjct: 309 ILTNGGGIGVMATDAAEEAGLHLYDDLDELKVFSNYMPPFGSYKNPVDLTGMAGAESYEG 368

Query: 400 LIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTER 459
            I      P++  +   V+    A  DP        ++        +    +  + G   
Sbjct: 369 AIKAALEHPEMHSI--AVLYCQTAVLDPRDLADIVIRE---YNASGRKKPLVVAIVGG-- 421

Query: 460 DPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
                 + I  L + GI        A    AAL       A
Sbjct: 422 --IEAKEAIDRLNEEGIPAYPEPERAIKALAALYRWSRWKA 460


>UniRef50_Q2Y8E7 GCN5-related N-acetyltransferase n=2 Tax=Betaproteobacteria
           RepID=Q2Y8E7_NITMU
          Length = 889

 Score =  269 bits (688), Expect = 2e-70,   Method: Composition-based stats.
 Identities = 72/475 (15%), Positives = 132/475 (27%), Gaps = 61/475 (12%)

Query: 57  NNATPNDICVAIRSEAADAGIAQ-AIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQ 113
              TP    VA+   +  +G     + + + ++  Q      +     +     + S   
Sbjct: 8   PLFTPRS--VAVFGASNTSGKVGYVVFENMLKSGFQGALYPINPKYPEVQGRPAYSSIGV 65

Query: 114 KLPDANLALISVAGEYAAELANQALDRNLNV-MMFSDNVTLE---DEIQLKTRAREKGLL 169
                 LA+I+   +    +     +  +   ++ +     E    E QL   AR  G+ 
Sbjct: 66  IHEPVELAVIATPPQTVPGIIENCGNEGVKAAIIITAGFQEEGDRLEEQLLATARAFGIR 125

Query: 170 VMGPDCGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGL 226
           ++GP+C   M     L           GNI  +  SG     +         G +  + +
Sbjct: 126 LVGPNCLGIMRPSIGLNATFYKGGANSGNIAFVSQSGALCTAILDWAQNNDVGFSSIVSM 185

Query: 227 GGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALF 286
           G          +     L+ L AD  ++ +    +   +A R           KP + + 
Sbjct: 186 G------SSTDVDFGEILDYLVADTATQSILMYIEGIRDARRFMSALRAATRLKPVIVVK 239

Query: 287 LGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLY--------- 337
           +G   A A+      A+ +         L+RV A R             L          
Sbjct: 240 VGRHAAGAKAARSHTAALVGADNVFNAALNRVGAVRVQTVTQLFTAAKALSLNFCRFGNR 299

Query: 338 --------TGGTLAAEAAGLLAGHLGVEADDTH----QHGMMLDADSHQIIDLGDDFYTV 385
                     G +AA+ A  L   L    D T     QH     +  + +  +GD     
Sbjct: 300 LAIVTNGGGPGVMAADRAEDLGLVLAPLEDATLQYLDQHLPQHWSHGNPVDIIGDAGADR 359

Query: 386 GRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDN 445
            R             +        V  +L   ++   A   P  S  +    + A     
Sbjct: 360 YR-----------HAVKACLEDENVDGVL--TILTPQAMTAPLESAQALIALSAAHC--- 403

Query: 446 QPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
                +A   G        +        A I    +   A  + + L        
Sbjct: 404 --KPLLACWMGET----QVASAREAFARARIPYFRTPEPAVEVFSHLSAYYRNQQ 452


>UniRef50_B6YXJ0 Acetyl-CoA synthetase II (NDP forming), alpha subunit n=5
           Tax=Thermococcaceae RepID=B6YXJ0_THEON
          Length = 459

 Score =  268 bits (686), Expect = 3e-70,   Method: Composition-based stats.
 Identities = 65/449 (14%), Positives = 133/449 (29%), Gaps = 33/449 (7%)

Query: 65  CVAIRSEAADAGIAQ-AIMQQLEEAL-KQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
            +A+   + D       + + L++    ++   +   + +  V+ + +      +  LA+
Sbjct: 11  AIAVIGASNDPLKLGYEVFKNLKDYKDGKVYPVNVKDEVVQGVKAYKNVKDIPDEVELAV 70

Query: 123 ISVAGEYAAELANQALDRNLNVMM-FSDNVTL------EDEIQLKTRAREKGLLVMGPDC 175
           + V   +  +      ++ +  ++  +            +E +L   A   G+ ++GP+C
Sbjct: 71  VVVPKRFVKQTIIDCGEKGVKGIILITAGFGEVGEDGKREERELVEIAHRYGMRIVGPNC 130

Query: 176 GTSMIAG--TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
              M         F     +G+I  I  SG     +  +    G G +  + +G      
Sbjct: 131 VGIMNTHNDMNATFVANAKKGDIAFISQSGALGAGIIYKTIKEGIGFSKFVSIGN----- 185

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAV 293
            +  +     +E L+ D +S+ +A   +   +  +   V       KP + L  G + + 
Sbjct: 186 -MADVDFAEFMEYLANDPESKAIALYIEGIKDGRKFMEVAKRVTKKKPVIVLKAGKSESG 244

Query: 294 ARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICG----LYTGGTLA--AEAA 347
           AR  +    S             +                      L  G  +A    A 
Sbjct: 245 ARAASSHTGSLAGSYKIYEAAFKQSGIIVADTIDDMLSMARAFTQPLPKGKRVAIMTNAG 304

Query: 348 GLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTL---RNQLIADL 404
           G              +   + +     +         V  P  MI         +    L
Sbjct: 305 GPGVLTADEIDKRGLKLANLEEKTMGGLRSFLPPMAAVKNPVDMIASARGEDYYRTAKLL 364

Query: 405 GAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCR 464
              P V +L+   V+   A   P         +A     + +P      V G        
Sbjct: 365 LEDPNVDMLIAICVVPTFAGMTPT-EHAEGVVRAVKEVNNGKP------VLGLFMAGYIS 417

Query: 465 SQQIATLEDAGIAVVSSLPEATLLAAALI 493
                 LE AGI       +    A AL+
Sbjct: 418 EPAKEVLEKAGIPSYERPEDVASAAYALV 446


>UniRef50_D0L1W1 CoA-binding domain protein n=1 Tax=Halothiobacillus neapolitanus c2
           RepID=D0L1W1_HALNC
          Length = 900

 Score =  267 bits (681), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 69/474 (14%), Positives = 137/474 (28%), Gaps = 42/474 (8%)

Query: 62  NDICVAIRSEAADAGIAQA-IMQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDA 118
           N   VAI   +   G     ++  L +A  + A    +     +  +             
Sbjct: 11  NPRGVAIFGASERKGAVGTMVLANLVDAGFKGAIVPVNPKYTQVQGLPCVPDLLHLDQPV 70

Query: 119 NLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDE----------IQLKTRAREKG 167
           +LA+I+        +  Q     +   ++ S       E           +    A++ G
Sbjct: 71  DLAVIATPSVSVPGILRQCGMAGVKSAVILSAGFGEGGEADRSDGKRLMRESLELAQQFG 130

Query: 168 LLVMGPDCGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           + +MGP+C   M     L      N    G + ++  SG  +  +       G G +   
Sbjct: 131 MRLMGPNCLGLMRPSIGLNATFSHNQAFPGKLALVSQSGALVTAVLDWAQSRGVGFSAIA 190

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
             G      +   +     L+ L+ D ++  +    +   +A          A  KP + 
Sbjct: 191 STG------DAADLDFGDLLDYLALDTQTTGILLYIEGIKDARHFLSGLRAAARMKPVIV 244

Query: 285 LFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAA 344
           L      A ++       + +         L+R    R             L +  +L  
Sbjct: 245 LKSARHAAGSKAAATHTGALIGADDVFDAALTRAGVVRVERITQWFSAAQILASSLSLRG 304

Query: 345 EAAGLLAGHLGV---EADDTHQHGMMLDADSHQIIDLGDDF----YTVGRPHPMID---P 394
           +   +L    G      D      + L   S   +   +      ++ G P  +I     
Sbjct: 305 DQLLILTNGGGPGVMATDRAADLNVPLAKLSDGTVTALNAALPATWSHGNPMDIIGDATA 364

Query: 395 TLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATV 454
              +  +    A P V +++  V++   A  DP A   +                 +A  
Sbjct: 365 ERYDTALRLSLADPGVDMII--VMLTPQAMTDPTACAQAVID--VVNSQTGYKKPVLACW 420

Query: 455 TGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI-HPLSPAAQQHTPSL 507
            G     +  ++     + A I    S   A    + L+ H  +      TP  
Sbjct: 421 MGE----KLVNEARDMFDAANIPQFRSPETAVEALSYLLAHRRNRQVLMQTPGP 470


>UniRef50_C9R913 Acetyl coenzyme A synthetase (ADP forming), alpha domain protein
           n=2 Tax=Clostridia RepID=C9R913_AMMDK
          Length = 699

 Score =  266 bits (680), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 79/524 (15%), Positives = 151/524 (28%), Gaps = 77/524 (14%)

Query: 66  VAIRSEAADAGIAQAIMQQ---LEEALKQLAQGSGSSQALTQVRRWDSACQKL-PDANLA 121
           VA+   + D      I+ +         +L   +  +  +  ++ + +         +LA
Sbjct: 11  VAVVGASQDRSKIGNIILRNIIASGYQGKLYPINPRAGEIEGLKAFPAVSALGRGAVDLA 70

Query: 122 LISVAGEYAAELANQALDRNLNV-MMFSDNV------TLEDEIQLKTRAREKGLLVMGPD 174
           +++V   +  ++A    +  +   ++ S          LE E +L    R+ G+ ++GP+
Sbjct: 71  VVAVPAPFVLDVARDCGEAGVKALVVISAGFKETGKEGLEREKELVAICRQYGMRLLGPN 130

Query: 175 CGTSMIAGTPLAF---ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
           C   M   TPL     A    +G I  I  SG  +  +       G G +  + +G +  
Sbjct: 131 CVGVMDTHTPLNASFAAGFPHKGEIAFISQSGAMLVAILDWSMREGIGFSQFVSMGNK-- 188

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
                 +     +E  + D  ++V+    +   E  R   V       KP V L  G + 
Sbjct: 189 ----ADLDETDLIEAAANDPHTKVILCYLEDIKEGQRFLEVAERVTREKPVVVLKSGVSE 244

Query: 292 AVARDENVWFASSLDEAARLACLLSRVTARR--------------NAIAPVSSGFICGLY 337
           A A+  +    +             +    R                        +  + 
Sbjct: 245 AGAKAASSHTGALAGSNIAYDAAFRQAGVIRVQSMRELFDLAVVFARQPIPRGRRVAVVT 304

Query: 338 TGGTLA------AEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPM 391
             G          E  GL       E  +  +  +  +A     +D+  D          
Sbjct: 305 NAGGPGIVTADSVERQGLEMARFSRETAEELRSQLPREASVFNPVDVLGDARV------- 357

Query: 392 IDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAI 451
                    I  + A   V  +L  V++   A +DP        +              +
Sbjct: 358 ---DRFQVAIEKVLADENVDGVL--VLLCPTAVSDPEGVA----RVMAELHARFSHKPML 408

Query: 452 ATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLS---PAAQQHTP-SL 507
               G E      +  +  L  AGI   +    A    A L+H  S      ++  P   
Sbjct: 409 GVFMGGE----SMAGGVEILNLAGIPCFTFPELAVGALAGLVHYGSIKARPPKEEVPVYP 464

Query: 508 LENVAVINIGLRSFALELQS-------------ASKPVVHYQWS 538
                 +   L     E +                 PV   Q +
Sbjct: 465 DVRPEEVRRILERARQERRRSLLSSEAAAVASAYGIPVAPIQLA 508


>UniRef50_Q47QC9 Probable 6-carboxyhexanoate--COA ligase n=1 Tax=Thermobifida fusca
           YX RepID=Q47QC9_THEFY
          Length = 692

 Score =  266 bits (679), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 99/535 (18%), Positives = 167/535 (31%), Gaps = 58/535 (10%)

Query: 51  FWHDDFNNATPNDICVAIRSEAA-DAGIAQAIMQQLEEALKQL--AQGSGSSQALTQVRR 107
              D      P+   VAI   +  +AG A   +  LE           +     +     
Sbjct: 1   MALDLKPLINPDS--VAIIGASPNEAGHAGRCLANLERTGYPGRIYPVNPKYDRIGAHTC 58

Query: 108 WDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNV-------TLEDEIQLK 160
           + SA       + A + V            L+R +  +               E + +L 
Sbjct: 59  YPSARDLPEQVDAAYLLVPARAVESALEDCLERGIRTVTICSAGYAELGAEGAERQRRLV 118

Query: 161 TRAREKGLLVMGPDCGTSMIAG------TPLAFANVMPEGNIGVIGASGTGIQELCSQIA 214
            RARE+G+ ++GP+C   +                    G+I ++  SG     L ++  
Sbjct: 119 ERARERGVRILGPNCIGVLNPVDTYVGCPTFNITYSYTPGSIALLSQSGGMAAALFNRAQ 178

Query: 215 LAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNA 274
               GI   + LG          I     L+   AD ++ V+A   +   +A R      
Sbjct: 179 GRTIGIRTMVSLGNE------ADIQMGELLDAFVADPQTRVIAIYIEQLRDAERFAAAAE 232

Query: 275 MKAT-GKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRN---------- 323
                GKP V L +G + A  R       +   E A  + ++  +               
Sbjct: 233 RARAAGKPIVLLKVGGSEAGRRTVLGHTGAMAGEQAVFSSMMRHLGVVEVHSIDDLLNTA 292

Query: 324 -----AIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDL 378
                   P          +GG     A    A   G+E     Q  +   ++  ++   
Sbjct: 293 YALSSLPLPAGPRLGALSPSGGECGYIADRASA--HGLEIPLPTQQTLDELSEKLKLARP 350

Query: 379 GDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKA 438
           G+   T G+   + D  L ++L+    A P + ++ L +   +G     A  L+     A
Sbjct: 351 GNPLDTTGQV--IGDGALLSELMQIFTADPNLDMITLSIPT-WGPYDSNA--LLPRIIDA 405

Query: 439 CAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH---- 494
             A      L A      TE       +    L ++GI   +S  EA    A L      
Sbjct: 406 VKACDKPAVLSAWTARNLTE-------RAEELLRESGICWFASSDEAIAALANLRRYAEL 458

Query: 495 PLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLAR 549
             +P+A    P  L    V  +   +    L     PVV    +P      + AR
Sbjct: 459 AQAPSATPPEPVSLPRPEVTELNEYAAKRLLAEGGVPVVAETLAPDTEAALRAAR 513


>UniRef50_C5A4T1 Acetyl-CoA synthetase (ADP forming), alpha chain (AcdA) n=9
           Tax=Thermococcaceae RepID=C5A4T1_THEGJ
          Length = 474

 Score =  265 bits (677), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 67/496 (13%), Positives = 139/496 (28%), Gaps = 71/496 (14%)

Query: 51  FWHDDFNNATP--NDICVAIRSEAADAGIAQAIM-----QQLEEALKQLAQGSGSS--QA 101
                     P  +   VAI       G    ++        E  + +      +     
Sbjct: 1   MAEKIVEELRPFFDPKAVAIIGATNKKGKVGNVIFENFRMNKERGIFKGNIYPVNPKLDE 60

Query: 102 LTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNVTL-------E 154
           +   + + S  +   D +LA+IS+   +  +   Q  ++ +  ++              +
Sbjct: 61  IEGYKVYHSVEELPDDTDLAVISIPAPFVPDTMRQIAEKGIKAVIIITGGFGELGEEGKK 120

Query: 155 DEIQLKTRAREKGLLVMGPDCGTSMIAGTPL-------AFANVMPEGNIGVIGASGTGIQ 207
            E ++   A+  G+ V+GP+C    +  T +       +  +    G I  +  SG    
Sbjct: 121 LEREIYEIAKANGIRVIGPNCVGVYVPDTGVDTVFLPESKMDRPQSGPIAFVSQSGAFAA 180

Query: 208 ELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAV 267
            +    A+AG GI   +  G +        +     ++    D+   V+ F  +   +  
Sbjct: 181 AMLDWAAMAGIGIGKMVSYGNK------IDVDDADLMDYFIHDDGINVVTFYIEGVKDGR 234

Query: 268 RLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAP 327
           +           KP +AL  G T   A+  +    S          +  +    R     
Sbjct: 235 KFMESAKRITRVKPVIALKSGRTEYGAKAASSHTGSLAGADTIYDAVFKQTGIIRAEDFE 294

Query: 328 ----------------VSSGFICGLYTG---GTLAAEAAGLLAGHLGVEADDTHQHG--- 365
                                I  +  G   G +A++A       +   +++T +     
Sbjct: 295 HMFDLAKAFAALKDKLPKGDRIGIITDGGGAGVMASDAVAKFGLRMAELSEETIKFLKEN 354

Query: 366 MMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATA 425
               A +    D+  D           D       I      P V  +L+ V+       
Sbjct: 355 FPPHAVAGNPTDVVGDT----------DAERYRVAIEGFVNDPNVDAILVIVLFQVPLLE 404

Query: 426 DPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEA 485
           +             A          +A   G     +   +    LE+ G+ V  +    
Sbjct: 405 E------EKIIDILAEYQKKSDKPIVAVAMGG----KKTDRYARMLEEKGVPVYPTPERG 454

Query: 486 TLLAAALIHPLSPAAQ 501
               A L+       +
Sbjct: 455 VRALAGLVRYAEYLKK 470


>UniRef50_A4YGK5 CoA-binding domain protein n=15 Tax=Archaea RepID=A4YGK5_METS5
          Length = 660

 Score =  265 bits (676), Expect = 4e-69,   Method: Composition-based stats.
 Identities = 66/524 (12%), Positives = 162/524 (30%), Gaps = 71/524 (13%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGSGS--SQALTQVRRWDSACQKLPDANLALI 123
           +A+   + +      ++ +   +  +      +  S+ +  V+ + S      D +LA+I
Sbjct: 12  IAVVGASRNREKVGNVIFRNVASTFRGKVYPVNNKSETIEGVQSYKSLKDIQDDVDLAII 71

Query: 124 SVAGEYAAELANQALDRNLN-VMMFSDNV------TLEDEIQLKTRAREKGLLVMGPDCG 176
           SV  E    +  +A ++ +   ++ +           + E ++ + A + G+  +GP+  
Sbjct: 72  SVPRESVPGVMEEAGEKGVRSAIVITSGFREVGEEGEKLEREVASIANKYGIRFLGPNTM 131

Query: 177 TSMIAGTPLAFANV-MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREV 235
             +       FA   +  G I ++  SG     + +    +  G++  + LG +   +E 
Sbjct: 132 GLLTPDYNGTFAFADVKRGEIALVVQSGGIGAYMLNWAQKSRTGVSFLVSLGNQTDVKEY 191

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVAR 295
                   ++ L+ D +++ +    +  ++  +   V     + KP + +  G +   A 
Sbjct: 192 ------EVIDYLAKDPETKAIFVYIEGVSDGEKFLNVVPEATSRKPVIFIKGGASAQSAE 245

Query: 296 DENVWFASSLDEAARLACLLSRVTARRNA--------------IAPVSSGFICGLYTG-- 339
                  S           +  V                      P+    +    +G  
Sbjct: 246 AVKTHTGSLAGSYEVFKAAIKTVGGIFVENLKDFLNLSKLVNSSEPIREEILVVTNSGGH 305

Query: 340 GTLAAEAAGLLAGHL---GVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTL 396
           G L ++A       L       +   +  +   +     +DL  D           D  L
Sbjct: 306 GVLTSDAISRAGLSLVKIPERLNMELRKVLPPQSIPKNPLDLSGDA--------GRDRYL 357

Query: 397 RNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAW--QKACAARLDNQPLYAIATV 454
            +  I       ++ ++                  +      +     L+ +    I   
Sbjct: 358 NSLKIVSDLDCTKLVIV----------------ESLPFISCTEVAKVLLNFKGKGIIGVT 401

Query: 455 TGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVI 514
            G + D          LE A I V +   EA    + L+   SP  +      +++   +
Sbjct: 402 MGYDED-----SASRILESASIPVFTFPEEAVNAISKLVKRPSPRRKVRVTQPIDSAREL 456

Query: 515 NIGLRSFAL-----ELQSASKPVVHYQWSPVAGGNKKLARLLER 553
           + G    A       ++        +  +      ++LA  +  
Sbjct: 457 SKGKSFLADYEGLKLMELYGIRTPRWGIANTLEEAQRLADSIGY 500


>UniRef50_D2LIT8 CoA-binding domain protein n=1 Tax=Rhodomicrobium vannielii ATCC
           17100 RepID=D2LIT8_RHOVA
          Length = 911

 Score =  265 bits (676), Expect = 5e-69,   Method: Composition-based stats.
 Identities = 71/472 (15%), Positives = 146/472 (30%), Gaps = 46/472 (9%)

Query: 66  VAIRSEAADAGIAQA-IMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           V +   +   G     + + L +       A  +    A+     + S         LA+
Sbjct: 15  VVLIGASERQGSIGKHVAENLLKGGFTGDIAFINPKRPAILGQPCFKSVDALPFTPGLAV 74

Query: 123 ISVAGEYAAELANQALDRNLNV-MMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           ++   E    +  +   +     ++ +  V+ +   ++   AR   L ++GP+C    + 
Sbjct: 75  VATPPETVPGVIEELGRKGCRAAVVITAGVSGDLRKRMLEAARPHLLRIIGPNCLGMQVP 134

Query: 182 GTPL--AFANVM-PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGI 238
              L  +FA V+   G++ ++  SG     +    ++ G G +H + +G      +   +
Sbjct: 135 RLGLDASFAQVLGKAGSVALVSQSGAITTAMLDWASVEGVGFSHVVSIG------DAADV 188

Query: 239 SALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDEN 298
                L+ L+ +  S  +    +   +A +        A  KP +A+  G  P  A+   
Sbjct: 189 DLGDMLDYLAGETTSRAVFLYIESVGDARKFMSAARRCARVKPVIAIKAGRHPEGAKAAA 248

Query: 299 VWFASSLDEAARLACLLSRVTARR--------------NAIAPVSSGFICGLYTGGTLAA 344
               +           L R    R                +  +    +  +  GG    
Sbjct: 249 SHTGALAGSDNVYGAALRRAGVLRVTDLDAMFDAAEMLAYVPAMPGDRVAIVTNGGGAGV 308

Query: 345 EAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI---DPTLRNQLI 401
            A   L    G  A    +    LDA            ++ G P  +I    P      +
Sbjct: 309 LAVDSLTDFRGTLATLAPETIDALDAA-------LPTTWSRGNPVDIIGDAGPDRYRATL 361

Query: 402 ADLGAKPQVRVLL-LDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERD 460
             + A P    +L ++      ++ D A ++V+A Q+    R   +    IA        
Sbjct: 362 DAVLADPNADAVLVMNCPTALASSLDGAKAVVAAVQEM---RAKGRNKPVIANWLAR--- 415

Query: 461 PQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVA 512
               +        A I    +   A      L+H    A  +   +      
Sbjct: 416 -HDETGIRDAFAAAKIPSYETPIAAVRGMMHLVH-YRRAQTELMQTPPALPE 465


>UniRef50_Q8TVZ2 Acyl-CoA synthetase (NDP forming) n=1 Tax=Methanopyrus kandleri
           RepID=Q8TVZ2_METKA
          Length = 446

 Score =  263 bits (672), Expect = 1e-68,   Method: Composition-based stats.
 Identities = 78/449 (17%), Positives = 146/449 (32%), Gaps = 35/449 (7%)

Query: 65  CVAIRSEAADAGIA-QAIMQQL-EEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
            VA+   + D       I + L  +    +   +  +  L   R + S  +     +LA+
Sbjct: 9   AVAVVGASRDPSKVGHGIFRNLLRDFDGPVYPVNPHADELLGRRCYPSLLELPERVDLAV 68

Query: 123 ISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           I+V      E+  +A +  +   +     FS+    + E +L   AR+ G+ ++GP+C  
Sbjct: 69  IAVPARVVPEVVREAGEAGVPYCVVISAGFSEAGNEDLERELVRTARKVGVRLVGPNCLG 128

Query: 178 SMIAGTPLAF---ANVMPEGNIGVIGASGTGIQELCSQIAL-----AGEGITHAIGLGGR 229
            + A   L     A   P GNI  +  SG     +    +       G G +  + LG  
Sbjct: 129 IINARIGLNASFAAESPPPGNIAFVTQSGALATSVIDWFSSGDVGTVGVGFSKFVSLGN- 187

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
                   +     LE L+ D+ ++V+    +   +  R     +  A  KP + L  G 
Sbjct: 188 -----AADLDFPDFLEYLAEDDDTDVVVLYLEGVKDGPRFLDALSECAGRKPVIVLKGGR 242

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGL 349
           T A A        S          L+             +      L   G   ++   +
Sbjct: 243 TEAGAEAVGTHTGSLAGSGEVYEGLVEGEGGIFVGGFEEAFDAAKLLAKAGPPTSDRVLI 302

Query: 350 LAGHLG---VEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDP-TLRNQLIADLG 405
           +    G   +  D  H+ G  L   +     L  +  T      + D    R ++  +  
Sbjct: 303 VTNAGGGGILATDALHELGFELPEPAGDPSVLPPEAATGNPVDVLGDADAERYRVALEEF 362

Query: 406 AKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRS 465
           A P     ++ V++   +  +P  +      +A    ++  P   I    G        +
Sbjct: 363 ADPDRYGAVM-VILTPQSVTEPVKT-----ARAVVEFVEEFPGPVIGVWMGR----HSVA 412

Query: 466 QQIATLEDAGIAVVSSLPEATLLAAALIH 494
             I  LE+ G+    S   A         
Sbjct: 413 LGIRVLEEGGVPTFPSPERAARALYHAAR 441


>UniRef50_A3DLQ0 Acetyl-CoA synthetase (ADP-forming) alpha subunit / branched-chain
           acyl-CoA synthetase (ADP-forming) alpha subunit n=4
           Tax=Archaea RepID=A3DLQ0_STAMF
          Length = 467

 Score =  263 bits (671), Expect = 1e-68,   Method: Composition-based stats.
 Identities = 70/466 (15%), Positives = 135/466 (28%), Gaps = 55/466 (11%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQLAQGSGSS--QALTQVRRWDSACQKLPDANLAL 122
           +AI   +   G     IM+ + E   +      +     +   + + S  +   + ++A+
Sbjct: 16  IAIIGASRSPGKIGHTIMKNIIEYGYKGKIYPINPKADEILGYKAYKSVVEVPDEIDMAI 75

Query: 123 ISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           I V  +   ++A +   + + V++     FS+   +E E +L   AR  G+ ++GP+   
Sbjct: 76  IVVPEQVVPKVAEECGKKGVKVLVVITSGFSEVGNVEAERKLVEIARRYGMRILGPNIFG 135

Query: 178 SMIAGTPLAFANVMP---EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSRE 234
                  L          EG I  I  SG     L     +   GI+  + +G       
Sbjct: 136 IAYTPAKLNATFGPKDVLEGPIAFITQSGALGIALMGWTIMEEIGISALVSMGN------ 189

Query: 235 VGGISALTALEMLSADEKSEVLAFVSKP--PAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
           +  I  +   + L+ D  ++V+    +   P    +           KP + +  G +  
Sbjct: 190 MADIDVIDVSKYLANDPNTKVITIYLEGLKPGTGRKFIEEMKKVTVKKPVIVIKAGRSKR 249

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTG------------- 339
            A        S             +    R         +     +              
Sbjct: 250 GAAAAASHTGSLAGSDNLYQAAFKQAGIIRAYTTEEMFDWARAFASQPIPRGEETIIITN 309

Query: 340 ----GTLAAEAAGLLAGHL---GVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI 392
               G LA +AA      L     E  +  +  M     +   IDL              
Sbjct: 310 GGGVGVLATDAAEEHNVKLLDPSPELKEKFKKTMPWFGSAKNPIDLTGQAVV-------- 361

Query: 393 DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIA 452
                 + +       ++  ++L       A  DP     +  +     +        +A
Sbjct: 362 --ENYVEALRTAFESDEIHNIILLY--CRTAILDPRDLANAIVKLYGEYKGTAHSKPLVA 417

Query: 453 TVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSP 498
              G E       + I  L   GI    S   A    A +I  +  
Sbjct: 418 GFVGGE----DVREAIRLLNKNGIPAYPSAERAVASIAKMIWYMRY 459


>UniRef50_B6YUH0 Archaeal succinyl-CoA synthetase (NDP forming), large subunit n=9
           Tax=Thermococcaceae RepID=B6YUH0_THEON
          Length = 469

 Score =  261 bits (667), Expect = 4e-68,   Method: Composition-based stats.
 Identities = 70/481 (14%), Positives = 142/481 (29%), Gaps = 73/481 (15%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQ------VRRWDSACQKLPDAN 119
           VA+   +   G     + +      +    + + +             + S  +   + +
Sbjct: 15  VAVIGASNVPGKVGNAIMRSITLKYEGKVYAVNVKGGEVEVNGKKFPVYRSIKEISDEID 74

Query: 120 LALISVAGEYAAELANQALDRNLN-VMMFSDNVTLE----DEIQLKTRAREKGLLVMGPD 174
           +A+I+V  ++  ++ ++  ++ +   ++ S           E ++  RAR+ G+ ++GP+
Sbjct: 75  VAVIAVPAKFVPDVIDECGEKGVKGAVVISAGFKEAGRADLEEEIVKRARKWGIRLVGPN 134

Query: 175 CGTSMI--AGTPLAFAN-----VMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLG 227
           C        G    F         P G I  +  SG     +    A    G++  I LG
Sbjct: 135 CLGVTNLENGFDCNFNPPERQARPPAGKIAFMSQSGAFGAAILDWAASHKIGMSKFISLG 194

Query: 228 GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFL 287
                  +  +     +  L  D K+ V+    +   +  +           KP + L  
Sbjct: 195 N------MADLDESDFMAYLGEDPKTGVITGYIEGVKDGRKFFNTAKEVTLKKPVIILKS 248

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAA 347
           G T A A+       S     A       +               +  L+      A+A 
Sbjct: 249 GRTEAGAKAAASHTGSLAGSYAIYQAAFKQAGVLEA-------KSMRQLFN----YAKAL 297

Query: 348 GLLAGHLGVEADDTHQHGMMLDADSHQIIDLGD---------------DFYTVGRPHPMI 392
            +    +G         G      S  +++ G                D      PH M 
Sbjct: 298 AMQKPAMGNRVAIVTNGGGAGVMMSDGLLERGMELAEFTEQTNERFRKDIEEGKLPHHMS 357

Query: 393 ----------DPTLRNQLIAD-LGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAA 441
                      P+ R +         P V VL+   VI    +      +V A  K    
Sbjct: 358 YKNPIDVIGDAPSNRYERAMRYALEDPNVDVLV---VIALFQSPALDEGIVDAVAKMQEY 414

Query: 442 RLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQ 501
               +P+  +A             +    +E  G+ V  ++ +      AL+       +
Sbjct: 415 ---GKPIVFVAP------GGDYPHKMARNIELKGVPVYETVEDGVDAVYALVRYGEWLRE 465

Query: 502 Q 502
            
Sbjct: 466 N 466


>UniRef50_A4J695 CoA-binding domain protein n=6 Tax=Peptococcaceae
           RepID=A4J695_DESRM
          Length = 701

 Score =  261 bits (667), Expect = 4e-68,   Method: Composition-based stats.
 Identities = 56/464 (12%), Positives = 140/464 (30%), Gaps = 53/464 (11%)

Query: 66  VAIRSEAADAGIAQAIM-QQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VAI   +  AG    ++ + +  +         + +   +  +  + +  +     +LA+
Sbjct: 13  VAIIGASKKAGKVGNVLMKNVINSGFTGKIFPVNPNEYEIEGLTCFSTLSEIPNQIDLAV 72

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTL------EDEIQLKTRAREKGLLVMGPDC 175
           + V      E+  +    ++   ++ S   +       + E +L +  ++ G+ ++GP+C
Sbjct: 73  VCVPALNCPEVLEECGKHSIKNAVVISSYFSEIGPEGLQLEKRLVSICKKYGIHLLGPNC 132

Query: 176 GTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
              M    PL  +   +    G+IG I  SG  +  +         G +    LG +   
Sbjct: 133 EGMMDTRIPLNASISPSFPKRGDIGFISQSGAMLLSIMDWSRTVSLGFSRVFSLGNK--- 189

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                +S    ++ L+ D  ++V+    +   +      V +     KP + L  G + A
Sbjct: 190 ---ADVSETDLIKCLANDPLTKVILCYIEDVQKGKEFLEVASKATKKKPVIILKSGTSQA 246

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAG 352
                +    + +          ++    R          +  L+   T  +        
Sbjct: 247 GTLAASSHTGALVGSDLAYETAFTQAGILRART-------MTELFDLATCFSYQPLPQGD 299

Query: 353 HLGVEADDTHQHGMMLDADSHQII--------------DLGDDFYTVGRPHPMI---DPT 395
            + +  +      +  D   +  +              +L      +  P  ++      
Sbjct: 300 RVAIVTNAGGAGIVASDTIENTGLSMARFEKETLDNLRELLPTEANIYNPIDVVFDAKAD 359

Query: 396 LRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVT 455
                +  +   P V  +++ V     A  +  A       K       +      A   
Sbjct: 360 RYAFALETILNDPNVDSVVILVCPTAAADPENIAG------KIIELHNKHPDKPVFAAYM 413

Query: 456 GTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPA 499
           G        ++ +  L  A I   +    A    + ++     +
Sbjct: 414 GGFA----LAEGVKMLTRAKIPTFTFPEPAIHSISGMVKYARHS 453


>UniRef50_Q1N4R6 Acyl-CoA synthetase (NDP forming) n=1 Tax=Bermanella marisrubri
           RepID=Q1N4R6_9GAMM
          Length = 910

 Score =  261 bits (666), Expect = 6e-68,   Method: Composition-based stats.
 Identities = 67/467 (14%), Positives = 153/467 (32%), Gaps = 43/467 (9%)

Query: 66  VAIRSEAADAGIAQAI-MQQLEEALKQLAQGSGS---SQALTQVRRWDSACQKLPDANLA 121
           +A+   +          +Q L+ A  + +  + +    + +  V       +   D +LA
Sbjct: 15  IAVIGASEKTTSMGGAVIQNLKSAGFKGSVYAVNIRRYKTVHGVPCVSKIGRLPKDIDLA 74

Query: 122 LISVAGEYAAELANQALDRNLNVMMF-SDNVTLEDEIQ-------LKTRAREKGLLVMGP 173
           +I        ++  Q     ++ ++  +  ++ +   Q       L+  +RE  + +MGP
Sbjct: 75  IICTPAPTIEKIIKQLGKIGIHAVIILTGGISRKRAEQFRPSKNPLRQLSREYDVRIMGP 134

Query: 174 DCGTSMIAGTPLAFANVM---PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
           DC   +I    L  +        G +  +G SGT    L       G G +H + +G   
Sbjct: 135 DCLGLLIPDLKLNASYSHIQALPGKVAYLGQSGTLASALLDWAHGRGIGFSHFLTIG--- 191

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
              +   ++   A++ LS+  + + +    +   +A          +  K  +A+  G  
Sbjct: 192 ---DSADVAMPDAIDYLSSQRQVKAIMLHLEQVHDAKAFVRAVRNASRSKLVLAIKSGRF 248

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLL 350
           P      ++  A           +L R    R          +  L     L  E   ++
Sbjct: 249 PQSQSPVDLIPAGLRHRDMVYEAILLRAGVLRVDSTEELFESVESLTRMKPLKGERLAIV 308

Query: 351 AGHLGV-------EADDTHQHGMMLDADSHQIIDLGDDFYTVGRPH---PMIDPTLRNQL 400
           A  +G           +  Q   +  +   ++ ++   +++   P    P   P +  ++
Sbjct: 309 ANGIGGAILAVDRLVHEGGQLATLSTSTIEKLSEILPPYWSQSNPVDITPEAGPKVYKKV 368

Query: 401 IADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERD 460
           +  +   P V  +L  V+    +  +P   + +           N     + +  G E  
Sbjct: 369 LELVEQDPNVDAIL--VLFSPNSVVNPVD-VANVVINHIKFHQKN----LLTSWMGGE-- 419

Query: 461 PQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA-QQHTPS 506
                +     +DAGI    +   A      ++         + TP+
Sbjct: 420 --SVERSRHVFDDAGIPTYDTPDRAIKAFMHMVRHQRNQELLRETPA 464


>UniRef50_B8FK52 Acetyl coenzyme A synthetase (ADP forming), alpha domain protein
           n=4 Tax=Proteobacteria RepID=B8FK52_DESAA
          Length = 726

 Score =  260 bits (663), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 73/466 (15%), Positives = 146/466 (31%), Gaps = 64/466 (13%)

Query: 66  VAIRSEAADAGIAQAIM-QQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+       G     +   + E          +  ++++   R + +      D ++A+
Sbjct: 14  IAVIGATDRIGSVGRAVVTNIIEGGFTGVLYPVNPRARSVVANRAYPTIKDIPDDVDMAV 73

Query: 123 ISVAGEYAAELANQALDRNL-NVMMFSDNV------TLEDEIQLKTRAREKGLLVMGPDC 175
           + V      ++  QA ++    V++ +          ++ E +LK   +E+G+ ++GP+C
Sbjct: 74  VIVPAPMVVDVVEQAAEKGASGVVVITAGFKEVGGEGVKLENELKAVVKERGIRLIGPNC 133

Query: 176 GTSMIAGTPLA----FANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
              +      +    FA  MP  GNIG I  SG     +         G +  I  G + 
Sbjct: 134 LGIINTAPGFSMNASFAQAMPAPGNIGFISQSGAMCTAVLDLAMGRNIGFSKFISFGNK- 192

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKAT--GKPTVALFLG 288
                  +S +  LE L  D  ++V+    +   +  +   V         KP +A+  G
Sbjct: 193 -----ADVSEIDLLEYLGQDPDTDVILMYLEDITDGRKFMDVARKITWKYKKPMLAIKSG 247

Query: 289 YTPAVARDENVWFASSLDEAARLACLLSRVTARRN--------------AIAPVSSGFIC 334
            +   A+  +    S     A    +  +   +R                +       I 
Sbjct: 248 RSEEGAKAVSSHTGSLAGSDASYDAIFQQSGIQRVEDVNEMFHYATAFSQMPLPRGNRIA 307

Query: 335 GLYTGG------TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRP 388
            +   G      T AA   GL     G          +   A+ +  +D+  D       
Sbjct: 308 IVTNAGGPGIMTTDAAVRHGLKLAEFGERTKRILGKNLPPTANINNPVDVIGDA------ 361

Query: 389 HPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPL 448
               D       +  +     V   +  VV+      D   +      +     L+    
Sbjct: 362 ----DYQRYEAALRAVVDDGDVDGAI--VVLTPQKMTDVLET-----AQMVPRVLEGVVK 410

Query: 449 YAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH 494
             + +  G        S  +  LE+  I   S   EA     +++H
Sbjct: 411 PVLCSFMG----IVDVSVGVRYLEENNIPNYSFPEEAVRALKSMVH 452


>UniRef50_A1U3K8 GCN5-related N-acetyltransferase n=4 Tax=Gammaproteobacteria
           RepID=A1U3K8_MARAV
          Length = 915

 Score =  259 bits (661), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 64/464 (13%), Positives = 137/464 (29%), Gaps = 42/464 (9%)

Query: 62  NDICVAIRSEAADAGIAQA-IMQQLEEALKQLAQGSGS---SQALTQVRRWDSACQKLPD 117
           N   +A+   +  A      +++ L            +    + +  V       +    
Sbjct: 11  NPESIAVIGASERADNLGGMVLRNLLGGGYPGRLVVVNQSDYENVHGVPCVRKVSKLDFS 70

Query: 118 ANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLED-------EIQLKTRAREKGLL 169
            +LA+I    +   ++  +  +  +   ++ +  ++             ++  ARE G+ 
Sbjct: 71  PDLAIICTPPDTVPKMIRKLGECGVRTAIVMTGGMSRTHSKTGQPLMYSVRDAARETGIR 130

Query: 170 VMGPDCGTSMIAGTPLAFANVM---PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGL 226
           V+GP+    M+    L           G +  +G SGT    +       G G ++ + L
Sbjct: 131 VLGPNTIGLMVPARHLNATYAHMGAIPGRVAFVGQSGTIASSVLDWAFARGVGFSYFLTL 190

Query: 227 GGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALF 286
           G      +   I     ++ L+ D ++  +    +      R      + +  KP +A+ 
Sbjct: 191 G------DGMDIDHDDLIDYLAQDTQTRAILLHIENIPNPRRFMSAVRVASRTKPVIAVK 244

Query: 287 LGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEA 346
            G  P      +   A           +L R    R          +  L     L  E+
Sbjct: 245 SGRVPESEWFTHALPAGIKRSDPVYDAMLQRAGVLRVDGLGQMFDALETLTRMRPLRRES 304

Query: 347 AGLLAGHLGV-------EADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPM---IDPTL 396
             ++A  +G         AD   +   + +    ++ +L   ++T   P  +     P L
Sbjct: 305 LAIMANGVGPGVLAVDRLADLGGELAELSEDTVRELGELLPPYWTRKNPIDLNYDATPEL 364

Query: 397 RNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTG 456
             + I  L   P V  +L  V+       D           +         L       G
Sbjct: 365 YGKAIKILAKDPNVANVL--VMYAPTLIEDSL-----QIADSVVQASKGTRLNIFTCWLG 417

Query: 457 TERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
                  R +       AG+    +  +A +     +       
Sbjct: 418 QSTVMDSREEFYR----AGLPSFFNPEKAVMAFMQHVRHQRIQR 457


>UniRef50_Q12WB1 Acetyl-CoA synthetase (ADP-forming), alpha and beta subunits n=5
           Tax=Euryarchaeota RepID=Q12WB1_METBU
          Length = 696

 Score =  258 bits (660), Expect = 3e-67,   Method: Composition-based stats.
 Identities = 75/516 (14%), Positives = 152/516 (29%), Gaps = 75/516 (14%)

Query: 66  VAIRSEAADAGIAQAIMQQ--LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALI 123
           VA+   +   G     +    LE    ++   +  +  +  +  + +       A LA++
Sbjct: 11  VAVIGASRTEGKVGRAVLDNLLESYSGRIIPINPKADEILGLPCYPTILDAPGGAELAVV 70

Query: 124 SVAGEYAAELANQALDRNLN-VMMFSDNVTLE------DEIQLKTRAREKGLLVMGPDCG 176
            V      +   +     +  V++ S             E +     +E G+ ++GP+C 
Sbjct: 71  VVPAVLVPDALEKCGLAGVKNVVVISAGFKEAGIEGSKLERRCAEIVKEHGMRMVGPNCL 130

Query: 177 TSMIAGTPLA---FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
             +   + L     A++  +GNI ++  SG             G G +  I LG +    
Sbjct: 131 GIIDTASGLNASFAASMAKKGNISMMSQSGAICTSTLDWADARGVGFSKFISLGNK---- 186

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAV 293
               +S    L  +  DE + V+A   +   +  +   +    +  KP + +  G T   
Sbjct: 187 --ADLSENDFLLEMEDDENTAVIAAYLEGVKDGPKFMEIARKVSRKKPIIVIKSGRTAVG 244

Query: 294 ARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTG-------------- 339
           +R  +    +            S+    R          +    +               
Sbjct: 245 SRAVSSHTGTLAGSDEAYNAAFSQSNVIRADSVEQLMDLMRAFSSQPIPDGRNIAIITNA 304

Query: 340 ---GTLAAEAAGLLAGHLGVEADDTHQHG---MMLDADSHQIIDLGDDFYTVGRPHPMID 393
              G LAA+A       L    + T +     +   +  +  +D+  D            
Sbjct: 305 GGLGILAADACQFAGLSLSSFDESTIEKLRSKLPPASSLYNPVDVLGDA----------R 354

Query: 394 PTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIAT 453
           P +    I  +   P V  ++L  +    A  +     +    +  A +  +     + +
Sbjct: 355 PDIYGFAIETILDDPNVDGVIL--LTSPQAMTE-----IKNIAEVVAEKCAHTKKPILCS 407

Query: 454 VTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA-QQHTPSLLENVA 512
             G         +  A L    I        A +  AAL         +   P   +   
Sbjct: 408 FVGGT----RIEEGEAILNRHHIPNYPFPERAVVSMAALCDYGVMREHEYVLPEKFDVDK 463

Query: 513 VI--------------NIGLRSFALELQSASKPVVH 534
                            +GL SF   L++   PVV 
Sbjct: 464 EFVSSLLKDAISNGRRTLGLESF-DILRAYGIPVVE 498


>UniRef50_C6C1C2 CoA-binding domain protein n=4 Tax=Desulfovibrio RepID=C6C1C2_DESAD
          Length = 708

 Score =  258 bits (659), Expect = 4e-67,   Method: Composition-based stats.
 Identities = 86/543 (15%), Positives = 164/543 (30%), Gaps = 77/543 (14%)

Query: 59  ATPNDICVAIRSEAADAGIAQ-AIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKL 115
            TP+   +A+   ++ +G     I+  L+ A         +     +  +  +       
Sbjct: 5   FTPSS--IAVVGASSVSGKIGNTILSNLQSAGYSGQLYPVNPRGGDINGISAYKKISDIG 62

Query: 116 PDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLED------EIQLKTRAREKGL 168
              +LA+++V  +    +  + L+  ++ V++ +      D      E+QL   A E G+
Sbjct: 63  TPVDLAVVAVPRDLVLGIFKELLELGVSSVVVITAGFKEVDHEGWLLEVQLAKLAEEHGV 122

Query: 169 LVMGPDCGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIG 225
            ++GP+C   + +   +  +        G++G    SG     +         G +  I 
Sbjct: 123 NLLGPNCLGVINSRGGVNASFATGNPLPGSMGFFSQSGALCVAVLDWALGEKVGFSKFIS 182

Query: 226 LGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVAL 285
           LG + +  E         +E L  D +++V+    +   +        A  +  KP + +
Sbjct: 183 LGNKAVINEAS------MIEYLGNDPETKVILGYVENIEDGREFMAQAAKVSMKKPILMM 236

Query: 286 FLGYTPAVARDENVWFASSLDEAARLACLLSRVTARR---------------NAIAPVSS 330
             G TPA AR  +    +             +    R                   P+  
Sbjct: 237 KAGTTPAGARAASSHTGAMAGSDQACDAAFRQSGVIRVEKLDELFNLAKAFSVQELPLGP 296

Query: 331 GFICGLYTG--GTLAAEA---AGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTV 385
                   G  G LAA+A   + +             Q  +   A  +  +DL  D    
Sbjct: 297 NLGIVTNAGGPGILAADACGESVMRMPTFSPGTIGELQRMLPGYASLYNPVDLLGDA--- 353

Query: 386 GRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDN 445
                  D     + +  +G  P V  LL  V+I      D          KA    +  
Sbjct: 354 -------DAESYGRAVRIVGHDPAVNSLL--VIIAPTVNLDFTE-----VAKAVVQGMGE 399

Query: 446 QPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPL----SPAAQ 501
                   + G     +  ++      +AG+ V     +A      +         P   
Sbjct: 400 VSKPVFCCLMGR----KNSAEAREIFAEAGVPVYDFPKQAVRAMDCMHKYAVWKGRPPRT 455

Query: 502 QHTPS--LLENVAVINIGLRSFALELQS---------ASKPVVHYQWSPVAGGNKKLARL 550
             TP   +    AV++  LRS   EL              P      +        +A  
Sbjct: 456 YFTPEHDVDAARAVVDNALRSGRSELVEFQARDIVTAYGLPTPESDLARSGDEAVAIAEQ 515

Query: 551 LER 553
           L  
Sbjct: 516 LGY 518


>UniRef50_B5YGJ9 Acetyl-CoA synthetase n=1 Tax=Thermodesulfovibrio yellowstonii DSM
           11347 RepID=B5YGJ9_THEYD
          Length = 695

 Score =  258 bits (659), Expect = 4e-67,   Method: Composition-based stats.
 Identities = 66/506 (13%), Positives = 141/506 (27%), Gaps = 68/506 (13%)

Query: 62  NDICVAIRSEAADAGIAQAIMQQ--LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDAN 119
           N   +A+   + +       + +  +     ++   +     +  +  + S        +
Sbjct: 7   NPSSIAVVGASQEEKKVGNAVLKNLINGYTGKIYPVNPGRTEILSLPCYPSVSAIPDRVD 66

Query: 120 LALISVAGEYAAELANQALDRNLN-VMMFSDNV------TLEDEIQLKTRAREKGLLVMG 172
           LA+I +  +  A+         +  V++ +          +  E ++    R  G+ ++G
Sbjct: 67  LAIIVIPAKAVADSLKDCAKAGVKGVVVITAGFKEVGGDGVAREKEIVEIVRSAGIKMVG 126

Query: 173 PDCGTSMI--AGTPLAFANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
           P+C   M        +FA  +P  G +     SG     +         G +  +  G +
Sbjct: 127 PNCLGVMNTKNKMNASFAAELPPEGRVAFFSQSGALGVAIIDWAIENNFGFSKFVSFGNK 186

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
                   ++    LE  + D  ++V+    +   +  R   +       KP + +  G 
Sbjct: 187 ------ADLNETDFLEYFAKDPDTDVILGYIEDVIDGKRFIEIAKEVTKIKPVILIKSGA 240

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARR---------------NAIAPVSSGFIC 334
           T A AR  +    +             +    R               +   P     + 
Sbjct: 241 TEAGARAASSHTGALAGSDRAFTEAFRKTGIIRTSGIQELFDTAEMFISRKTPKGRKLLI 300

Query: 335 GLYTG--GTLAAEAAGLLAGHLGVEADDTHQHG---MMLDADSHQIIDLGDDFYTVGRPH 389
               G  G +AA+ A  L   L      +       +   A  +  +D+  D  +     
Sbjct: 301 ITNAGGPGIIAADTADRLGIKLDPMTRTSIDTIAEKLPSTASLYNPVDIIGDATS----- 355

Query: 390 PMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLY 449
                     ++        V  +   V++   A  D     V        +  +N    
Sbjct: 356 -----ERYKIVLDQAIKDNSVEGIC--VILTPQAVTD-----VDNIADVVISSANNTDKP 403

Query: 450 AIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI-----HPLSPAAQQHT 504
             AT  G     Q     I  L+   I   +    A      L+          + +   
Sbjct: 404 VFATFIGG----QRVRNAINKLKGFRIPCFTDPSIAIHAYRKLVDFVQLKSKEISDELQI 459

Query: 505 PSLLENVAVINIGLRSFALELQSASK 530
               +N+  +          LQS   
Sbjct: 460 KIPEQNIEEVKK----IIQSLQSQGV 481


>UniRef50_C7MVA0 Acyl-CoA synthetase (NDP forming) n=1 Tax=Saccharomonospora viridis
           DSM 43017 RepID=C7MVA0_SACVD
          Length = 926

 Score =  258 bits (658), Expect = 6e-67,   Method: Composition-based stats.
 Identities = 77/480 (16%), Positives = 145/480 (30%), Gaps = 45/480 (9%)

Query: 66  VAIRSEAADAGIAQAIMQQ---LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   + D+      +       +    +   +    A+  VR + S  +     +LA+
Sbjct: 222 VAVIGASTDSTKIGYAVLSNLLAADFAGPVYPVNPEHVAVRGVRAYKSVLEIPGPVDLAV 281

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDC 175
           ++V  +    + + AL + +  ++        S    L  E++L   AR  G+ V+GP+ 
Sbjct: 282 VAVPADEVEAVLDGALAKGVQALVIVSAGFAESGPHGLHAELRLVKAARAHGMRVVGPNA 341

Query: 176 GTSMIAGTPLAFANV-----MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
              +     +             G  G    SG     + +     G G++  +  G R 
Sbjct: 342 LGVLNTDPTVRLNATLAPRLPRRGRTGFFCQSGALGIAILADAEARGLGLSTFVSAGNR- 400

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
                  +S    L+    D +++V+    +      +   +    A  KP VA+  G  
Sbjct: 401 -----ADVSGNDLLQYWETDPRTDVVLLYLESFGNPRKFARLARRLARSKPIVAVKSGRH 455

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLL 350
               +                    S V A       V    +  L+    + A      
Sbjct: 456 AVRPQLAATST----------EIDESSVQALFEQAGVVRVDTLAQLFDTALVFANQPLPA 505

Query: 351 AGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQV 410
              +G+  + +    +  D    Q + LG +   VG   P   P      +    A P V
Sbjct: 506 GSRIGIVGNSSAIALLAADTARAQGLTLGIEPVDVGSQAP---PEDFAAAVGRALASPDV 562

Query: 411 RVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIAT 470
             L++  V        P  +   A ++   A         ++T    E  P   +     
Sbjct: 563 DALVVVFVPPVAT---PGTAYARALRETVLATSPTLEKPIVSTFLAAEGVPDELA----V 615

Query: 471 LEDAGIAVV---SSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQS 527
            +D G        S P       AL   +  A  +  P     V    + L      +Q 
Sbjct: 616 TDDDGTVAFGSIPSYPSPERAVNALARVVRYAEWRRRPQG-TVVRPSGLHLERAQRLVQE 674


>UniRef50_C0GR98 GCN5-related N-acetyltransferase n=1 Tax=Desulfonatronospira
           thiodismutans ASO3-1 RepID=C0GR98_9DELT
          Length = 901

 Score =  258 bits (658), Expect = 6e-67,   Method: Composition-based stats.
 Identities = 79/537 (14%), Positives = 161/537 (29%), Gaps = 76/537 (14%)

Query: 66  VAIRSEAADAGIAQAI-MQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +   G   ++ M  +            +    A+  +  +    +     +LAL
Sbjct: 15  VAVIGASNRPGSIGSVVMHNMLRGGLPGPILPVNPRYDAVAGILAYPGVRELPLVPDLAL 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMFS--------DNVTLEDEIQLKTRAREKGLLVMGPD 174
           +    +    L  +   +    ++          D      + ++   A+E  + ++GPD
Sbjct: 75  VCTPPDTVPGLMQELGIKGTRTVLIMSRDLNKQLDESGQTLQQRVLKTAKEHSMRILGPD 134

Query: 175 CGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
           C   ++  + L  +     + +G I  +  S      +       G G +H I LG    
Sbjct: 135 CLGIIVPRSGLNASFGHTDIAQGKIAFVSQSDALGIAVLDWAGSKGIGFSHFISLG---- 190

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
             +   I     ++ L  D  S  +    +  + A +        +  KP V +      
Sbjct: 191 --DCLDIDFGDIIDYLKGDPHSTSILLYMESVSNARKFISAARSASRNKPLVVIKGDKFN 248

Query: 292 AVARDENVWFASSLDEAARLACLLSRVTARR--------------NAIAPVSSGFICGLY 337
             A  +  +  S +        +  R    R                  P+    +  L 
Sbjct: 249 ISAVRDASYIDSPVSTDDIYDGVFRRAGMLRVFDLAELFDAVEAMARYKPLRGDRLAILS 308

Query: 338 TGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPT-- 395
            GG  A  A  +L    G  A+ + Q    L               +   P  +ID    
Sbjct: 309 NGGGPAMMARDVLKTRGGSLAELSEQTRQQLQHG-------LQAELSHQEPVRIIDHASS 361

Query: 396 -LRNQLIADLGAKPQVRVL-LLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIAT 453
              ++ +  L     V  + ++ V   F ++ D A +++++           +    + T
Sbjct: 362 ETYSRALEILIQDQNVDAIMVIHVPTAFASSQDIAGAVINSL---------GRTRKNVIT 412

Query: 454 VTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA----------QQH 503
           V   E+D    +Q       AGI    +  +A  L   ++                    
Sbjct: 413 VWLGEKD---AAQARRMFALAGIPTYETPDQAARLFMDMVRYRRNQELLMETPDSVPSDF 469

Query: 504 TPSLLENVAVINIGLR---------SFALELQSASKPVVHYQWSPVAGGNKKLARLL 551
           +P  +   A+I   L               L   + PVV  + +  A     ++R L
Sbjct: 470 SPDPMAARAIIKNALDENRSFLSAPETNEVLSIYTIPVVPTRQAADAQEASLISREL 526


>UniRef50_B6YUE1 Acyl-CoA synthetase (NDP forming), large subunit n=2
           Tax=Thermococcus RepID=B6YUE1_THEON
          Length = 438

 Score =  255 bits (652), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 70/458 (15%), Positives = 132/458 (28%), Gaps = 57/458 (12%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQL---AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VAI     +  IA  I++ + E                     + ++   +     + A+
Sbjct: 10  VAIFGSFKEGAIAYEILRNIVEGGFDGRIVPVNPKGGTVEIAGKAFEIRPKLEEPVDAAI 69

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVT----LEDEIQLKTRAREKGLLVMGPDCGTS 178
           I++  ++   L ++  +     ++ S   +    +E E +L  +AR+ G+ ++GP+C   
Sbjct: 70  IAIPAKFVPSLIDEIGELIKGAVVISAGFSEVGNVELERELVEKARKHGIRIIGPNCAGI 129

Query: 179 MIAGTPL--AFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVG 236
                    +F   +  G + +I  SG       +       G +  +  G         
Sbjct: 130 FGVHGKFFGSFEVRVKPGGLALISQSGAFGGAALAMGNDERIGFSAFVSYGN------AA 183

Query: 237 GISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARD 296
            ++    L   + D+ ++ +A   +   +  R        A  KP + L  G + + AR 
Sbjct: 184 DLNESDFLRYFADDKNTKAIALYIEGVRDGRRFMEALRYAAGKKPVIILKAGKSKSGARA 243

Query: 297 ENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFIC--------------GLYTG--G 340
                 S             +  A                               +G  G
Sbjct: 244 AASHTGSLAGSYEIYRAAFKQAGAIEVEEMEGLFDAAKAFEMYEKAGRRVAVITNSGGPG 303

Query: 341 TLAAEAAGLLAGHLGVEADDTHQHG---MMLDADSHQIIDLGDDFYTVGRPHPMIDPTLR 397
            LA +    L   +   +D+T +     +         IDL  D           D    
Sbjct: 304 VLATDKLESLGLEIAQLSDETVEELRSFLPPQCSVKNPIDLIADA----------DYERY 353

Query: 398 NQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGT 457
            + I  +     V  LL   VI       P+  +  A   A            I      
Sbjct: 354 KKTIEIVCRDGNVDALL---VICVPPIFVPSEEIAKAVIDA------ECDKPVIVNFMAG 404

Query: 458 ERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHP 495
           E         +  LE+ GI    +   A    A L   
Sbjct: 405 EL----VRDGVKLLEEGGIKNFPTPERAAKALAWLSRR 438


>UniRef50_UPI0001B56A88 CoA-binding domain protein n=1 Tax=Streptomyces sp. AA4
           RepID=UPI0001B56A88
          Length = 947

 Score =  255 bits (652), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 74/480 (15%), Positives = 149/480 (31%), Gaps = 47/480 (9%)

Query: 66  VAIRSEAADAGIAQAIMQQ---LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +AD      +        +    +   +   +++  VR + S        +LAL
Sbjct: 261 VAVIGASADPTKVGHVAFANLLAADFAGAVYPVNPEHRSVRGVRAYPSVLDIPDPVDLAL 320

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNV-------TLEDEIQLKTRAREKGLLVMGPDC 175
           ++V  E    + +  L + +  ++             L  E++L   AR  G+ V+GP+ 
Sbjct: 321 VAVPAEAVESVLDACLAKGVKTLVIVSGGFAESGPLGLHAELRLVGEARAHGMRVVGPNA 380

Query: 176 GTSMIAGTPLAFANV-----MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
              +     +             G  G    SG     + +     G G++  +  G R 
Sbjct: 381 LGVLNTAKDVRLNATLAPRLPKRGRTGFFCQSGALGTAILADAGSRGLGLSTFVSAGNR- 439

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
                  +S    L+    D  ++++    +      +   +    A  KP VA+  G  
Sbjct: 440 -----ADVSGNDLLQYWETDPDTDLVLLYLESFGNPRKFARLARRLARSKPIVAVKSGRH 494

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLL 350
               R +    ++ +DEA         V A       V    +  L+    + A      
Sbjct: 495 A--VRPQLAATSAEVDEA--------SVQALFEQAGVVRVESLAQLFDTALVFAHQPLPA 544

Query: 351 AGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQV 410
              +G+  + +    +  D    + + L  D   +G   P   P      + +    P  
Sbjct: 545 GPRIGIVGNSSAIGLLAADTARAEGLRLAFDPVDIG---PQAGPDEFATAVREALDSPDT 601

Query: 411 RVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIAT 470
             L+            P A+   A ++A +    +     ++T    E  P   +     
Sbjct: 602 DALIAVFAPPVAI---PGAAYARALREAVSEMKQS--KPIVSTFLAAEGVPDELA----V 652

Query: 471 LEDAGIAV---VSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQS 527
           L D G+     + S         AL   +  AA +  P     V    + +      ++ 
Sbjct: 653 LSDDGVPTRGSIPSYSSPERAVNALARVVRYAAWRQRPQG-TLVRPSGLHVEQAQEIVRE 711


>UniRef50_C5BNQ0 Long-chain-fatty-acid--CoA ligase n=1 Tax=Teredinibacter turnerae
           T7901 RepID=C5BNQ0_TERTT
          Length = 897

 Score =  255 bits (651), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 71/483 (14%), Positives = 141/483 (29%), Gaps = 41/483 (8%)

Query: 66  VAIRSEAADAGIAQAI-MQQLEEALK--QLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   +       ++  + L  A    QL   +    ++     + S         LA+
Sbjct: 18  IAVFGASQRPNATGSVVFRNLIAAGFCNQLYAINPKYTSVDNHTCYRSLDDIDDHIELAI 77

Query: 123 ISVAGEYAAELANQALDRNLNV-MMFSDNVTLEDE------IQLKTRAREKGLLVMGPDC 175
           I+       ++  Q     +   ++F+      DE        L   AR+ G+  +GP+ 
Sbjct: 78  ITTPAHTVKDILKQCGKHKVKAAVIFAGGFAQPDEPGKVSEQALVEIARKYGIRFIGPNS 137

Query: 176 GTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
                  T +        +  GN+ ++  SG     +    A+   G +  + +G     
Sbjct: 138 LGIAHPSTNINATFGPGEVASGNLALVSQSGAVCTAVMDWAAVQDIGFSSVVSIG----- 192

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                +     L+ L +D K+  +    +   +A          A  KP + +  G   A
Sbjct: 193 -ACADLDFGDILDFLVSDGKTRSILLYVEGIRDARSFMCGLRAVARVKPVIVIKAGRHKA 251

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAG 352
                    ++ + +    A  L R    R             L  G  L  +   ++  
Sbjct: 252 AIEVTQSHNSARVGDDDVFAAALKRAGVVRGMHLGDLLAAANILARGTRLRGDKLAIITN 311

Query: 353 HLGV------EADDTHQHGMMLDADSHQIID-LGDDFYTVGRPHPMID---PTLRNQLIA 402
             G        A D H     L  ++H+ +D L   +++   P  ++           + 
Sbjct: 312 GGGPAAMACDRASDLHIPLAPLGEEAHKKLDKLLPHYWSHSNPVDILGDADADRYAAALE 371

Query: 403 DLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQ 462
            + A  +   ++  V++   AT DP      A  +     +       IA   G  R   
Sbjct: 372 IMLADTECHGVM--VMLTPQATTDPV-----AIAQRLIDIIKKTSKPVIACWMGENRVLP 424

Query: 463 CRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFA 522
                      AGI +      A    A L             +       I   +    
Sbjct: 425 ----ARRLFASAGIPIFRLPETAVQAFAYLATFFRNQKLL-LQTPPPLSQTITATIEDAH 479

Query: 523 LEL 525
             +
Sbjct: 480 TVI 482


>UniRef50_C5A3W6 Acetyl-CoA synthetase (ADP forming), alpha chain (AcdA) n=4
           Tax=Thermococcus RepID=C5A3W6_THEGJ
          Length = 458

 Score =  255 bits (650), Expect = 4e-66,   Method: Composition-based stats.
 Identities = 65/455 (14%), Positives = 137/455 (30%), Gaps = 33/455 (7%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEAL-KQLAQGSGSSQALTQVRRWDSACQKLPDANLALI 123
           +AI   + D       + + L++    ++   +   + +  V+ + +      + +LA+I
Sbjct: 12  IAIIGASNDPMKLGYEVFKNLKKYRDGRVYPVNVKDEVVQGVKAYKNVKDIPDEVDLAII 71

Query: 124 SVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQ------LKTRAREKGLLVMGPDCG 176
            V   +  +      ++ +   ++ +       E        L   A + G+ ++GP+C 
Sbjct: 72  VVPKRFVKQAIIDCGEKGVKGAVIITAGFGETGEEGKKEERELVEIAHKYGMRLIGPNCV 131

Query: 177 TSMIAGTPLAFANVM--PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSRE 234
             M     +    +M   +G+I  +  SG     +  +    G G +  + +G       
Sbjct: 132 GVMNTHNDMNATFIMDAKKGSIAFVSQSGALGAGIVYKTVKEGIGFSKFVSVGN------ 185

Query: 235 VGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVA 294
           +  +     +E L+   + + +A   +   +  +   V       KP +AL  G + + A
Sbjct: 186 MADLDFAELMEYLAETGEDKAIALYIEGLKDGRKFIEVAKKVTKKKPVIALKAGKSESGA 245

Query: 295 RDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICG----LYTGGTLA--AEAAG 348
           R  +    S             +                      L  G  +A    A G
Sbjct: 246 RAASSHTGSLAGSWKIYEAAFKQSGVLIAETIDDMLSMARAFTQPLPKGKRVAIMTNAGG 305

Query: 349 LLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTL---RNQLIADLG 405
                         +   + +    ++         V  P  MI         +    L 
Sbjct: 306 PGVLTADQIDKRGLKLADLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTAKLLL 365

Query: 406 AKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRS 465
             P V +L+   V+   A   P         +A     + +P      V G         
Sbjct: 366 QDPNVDMLIAICVVPTFAGMTPT-EHAEGVIRAVKEVNNGKP------VLGLFMAGYVSE 418

Query: 466 QQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
           +    LE+ GI       +    A AL+     A 
Sbjct: 419 KAKELLEENGIPSYERPEDVAAGAYALVQQAKNAG 453


>UniRef50_Q9UYT1 AcdA-4 acetate--coA ligase (ADP-forming), alpha chain n=3
           Tax=Pyrococcus RepID=Q9UYT1_PYRAB
          Length = 442

 Score =  253 bits (646), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 65/460 (14%), Positives = 133/460 (28%), Gaps = 57/460 (12%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQL---AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VAI     +  IA+ I++ + E   +                 RR++   +   + ++++
Sbjct: 10  VAIFGSFREGAIAREILRNIVEGGFEGKIIPVNPKGGTVEVAGRRFEIRKRLEEEVDVSI 69

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVT----LEDEIQLKTRAREKGLLVMGPDCGTS 178
           + +  +    L  +        ++ S   +    ++ E +L   A+E G+ ++GP+C   
Sbjct: 70  VVIPAKLVPGLIRELKGLTKGAVVISAGFSEVGNVDLEEELIKAAKEAGIRIIGPNCAGI 129

Query: 179 MIAGTPL--AFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVG 236
                    +F   +  G + +I  SG       +       G +  +  G         
Sbjct: 130 FGVHGKFFGSFEVRVNPGGLALISQSGAFGGAALAMGNEENVGFSAFVSYGN------AA 183

Query: 237 GISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARD 296
            +     L   + DE ++V+A   +   +  +         + KP + L  G + + A+ 
Sbjct: 184 DLDESDFLRYFADDENTKVIALYIEGVKDGRKFFEALKYATSKKPVIILKAGKSESGAKA 243

Query: 297 ENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFIC--------------GLYTG--G 340
                 S          +  +  A                               +G  G
Sbjct: 244 AQSHTGSLAGSYEIYKAVFKQGNAIEVEEMEELFDAAKAFEMYQSAGSRVAVITNSGGPG 303

Query: 341 TLAAEAAGLLAGHLGVEADDTHQHG---MMLDADSHQIIDLGDDFYTVGRPHPMIDPTLR 397
            LA +    L   +   +++T       +     +   IDL  D           D    
Sbjct: 304 VLATDKLEKLGLEIARLSEETVAKLREFLPPQCSTRNPIDLIADA----------DYERY 353

Query: 398 NQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGT 457
            + I  +     V  LL   VI       P+  +  A  +A            I      
Sbjct: 354 RRTIEVVCQDENVDSLL---VICVPPIFIPSEEIARAIIEAKC------NKPIIVNFMAG 404

Query: 458 ERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLS 497
           E       + +  L   GI    +   A      L    +
Sbjct: 405 EL----VKKGVELLNAHGIKNFPTPERAAKALYWLSKRKN 440


>UniRef50_A0LL44 CoA-binding domain protein n=2 Tax=cellular organisms
           RepID=A0LL44_SYNFM
          Length = 669

 Score =  253 bits (645), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 82/516 (15%), Positives = 152/516 (29%), Gaps = 74/516 (14%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQLAQGSGSSQA--LTQVRRWDSACQKLPDANLAL 122
           VA+   +  AG     I++ L E     A    + +A  +  +  + +        ++A+
Sbjct: 15  VAVIGASDSAGKLGHEILKNLIEGGFPGALYPINPKAEKILGLTCFKNVKDIPDQVDMAV 74

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLE------DEIQLKTRAREKGLLVMGPDC 175
           + +      +      ++ +   ++ +   +         + +L   A    + ++GP+C
Sbjct: 75  VIIPARMVPQAVRDCGEKGVKGAVIVTGGFSEAGAEGAKLQEELVRVASNYDIRLVGPNC 134

Query: 176 GTSMIAGTPLAFAN--VMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
                   P+  +   +  +G + VI  SGT    +    ++   G++  + LG R    
Sbjct: 135 QGVNNPHHPMCASWPLLTHKGRVAVISQSGTVGAAMMDWFSVEELGVSSFVSLGNR---- 190

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAV 293
               I  +  +E    D  ++V+A   +   +  R + V       KP V L  G TP  
Sbjct: 191 --ADIDEVDLIEYFEGDPNTKVIAVYIEGIKDPQRFRDVL--STLSKPLVVLKSGRTPGG 246

Query: 294 ARDENVWFASSLDEAARLACLLSRVTARRNAIA---------------PVSSGFICGLYT 338
                    S     A  A L  R    R                   P  +  +    +
Sbjct: 247 RVAAESHTKSLAGADAIYASLFRRHGVCRAETIEEFFDFAKGFAYLKPPSGNRILYITTS 306

Query: 339 GG-----TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID 393
           GG     T AAE  GL    L  E     +  +   A     +DL  D         +  
Sbjct: 307 GGSAILATDAAEQEGLSVSALPEELAGQLEGVIPPHAIRSNPLDLTGDANAKMFQEVIQR 366

Query: 394 PTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIAT 453
                  +  +   P                             +     +   L     
Sbjct: 367 ARPYYDTLGIIFGDP-------------------------ILDASEVVTPEANELVI--- 398

Query: 454 VTGTERDPQCRSQQIAT-LEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVA 512
             G         +     +   GI V  +        A LI P S A +  T   + +  
Sbjct: 399 FLGGAE----VERAERMKMHQRGIPVFPTPERGVKALAQLIPPKSKARKAQTTFPVASGR 454

Query: 513 VINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLA 548
           V  +GL      L+S     +   ++   G    LA
Sbjct: 455 V-QLGLYEGLQFLESKGFDCIISSFADSPGKAVHLA 489


>UniRef50_Q2RTE1 N-acetyltransferase n=13 Tax=Proteobacteria RepID=Q2RTE1_RHORT
          Length = 913

 Score =  251 bits (641), Expect = 5e-65,   Method: Composition-based stats.
 Identities = 66/535 (12%), Positives = 138/535 (25%), Gaps = 68/535 (12%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +  A      +M+ L            +   QA+  V  +          +LA+
Sbjct: 28  VAVIGASNQANTVGHLVMRNLLSGGFGGPIMPVNPKYQAVGGVLAYADVASLPVAPDLAI 87

Query: 123 ISVAGEYAAELANQALDRNLNV-MMFSDNVTLEDE-------IQLKTRAREKGLLVMGPD 174
           +    +       +  DR     ++ ++ ++   E             AR   + V+GP+
Sbjct: 88  VCSPPDSVPMAVAELGDRGTKACIVMTEGLSRAREAGGRSLQQATLDAARRHMVRVLGPN 147

Query: 175 CGTSMIAGTPLAFANVMPE---GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
               ++    L  +        G    I  SG     +       G G +H + LG +  
Sbjct: 148 SVGLLVPALGLNASFSHQPALPGKAAFISQSGALCTAVLDWAKGRGIGFSHFVSLGDK-- 205

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
                 +    A++ L A      +    +   +A +        A  KP + +  G   
Sbjct: 206 ----ADVDFGDAVDYLGAQPDVRAVLLYIETLTDARKFMSAARSAARNKPVIVIKSGRGE 261

Query: 292 AVARDENVWFASSLDEAARLACLLSRVTARRNAIA---------------PVSSGFICGL 336
             AR       +     +       R    R                   P+    +  L
Sbjct: 262 EGARAAASHTGNLAGTDSIHDIAFKRAGMLRVYSLEELFSAVETIAHTRRPMRGERLAIL 321

Query: 337 YTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTL 396
             GG +   A   L+   G  A  + +    L         + +     G          
Sbjct: 322 TNGGGIGVMAVDELSDRGGTLAKLSPETLARLHTVVPASTVVANPLNIGGSAPG----ER 377

Query: 397 RNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTG 456
               +  L     V  +L+       ++           +K        +         G
Sbjct: 378 YTAALEVLLDSHDVDAVLVMHAPSAFSSPS------DIARKVIDVARARRTASIFTCWVG 431

Query: 457 TERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPA----------AQQHTPS 506
                   ++      +A I   S+  E       ++                  + T +
Sbjct: 432 QA----SVTEARGLFAEAQIPTFSTPDEGVQGFMHMVDYRRNQDMLMETPPSLPSEFTAN 487

Query: 507 LLENVAVINIGLRSFALELQS---------ASKPVVHYQWSPVAGGNKKLARLLE 552
                 ++++ +    L +              P V    +  A   + +AR + 
Sbjct: 488 TNSARTIVDLAIERGHLIMSEPEAKAVFAAYGIPTVETHIAHTAEEAEDVARRMN 542


>UniRef50_Q3IFA9 Putative acyl-CoA synthetase, NAD(P)-binding, ATP-binding n=3
           Tax=Alteromonadales RepID=Q3IFA9_PSEHT
          Length = 888

 Score =  250 bits (638), Expect = 1e-64,   Method: Composition-based stats.
 Identities = 75/494 (15%), Positives = 144/494 (29%), Gaps = 52/494 (10%)

Query: 62  NDICVAIRSEAADAGIAQ-AIMQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDA 118
           N   VA+   +     A   +M+ L ++  +      + +  A+  V  + S        
Sbjct: 11  NPSSVAVIGASNTPTRAGYVVMRNLLQSGFKGPIMPVTPNHTAVHGVLAYPSIDALPKVP 70

Query: 119 NLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           +LA+I         +  Q      +  ++ +D ++   +  LK  AR   + ++GP+   
Sbjct: 71  DLAVICTNKNTLDLIIEQLGKLGCHNAIIIADGLSNAQKQTLKECARSHQVTLLGPNSLG 130

Query: 178 SMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSRE 234
            +I    L  +    V   G +  +  S      +         G ++ + +G      +
Sbjct: 131 LLIPHIGLNASFSHTVASPGKLAFVSQSAAVCSTILDWAKNKEIGFSYFVSMG------D 184

Query: 235 VGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVA 294
              I     L+ L  D K+  +        ++          A  KP + +  G T A A
Sbjct: 185 CLDIKFTELLDFLGRDAKTTAILLYIDNIEDSRSFISAARAAAFSKPVIVIKTGRTHAGA 244

Query: 295 RDEN-----VWFASSLDEAARLACLLSRVTARRNAIAPVSSGFI----------CGLYTG 339
                       + ++ +A      + RV   R   A   +  +            L  G
Sbjct: 245 IAAEAQSGIAHSSDAVYDALFQRAGMLRVNDLRELFAATQTLAMHPKLLKVEQLTILTNG 304

Query: 340 GTLAAEAAGLL------AGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID 393
           G     A   L         L  E  D     +     +   +D+  D            
Sbjct: 305 GGPGVMAVDELIQSSGKLTQLSEETCDALNKVIPRSEKASNPVDIFGDSA---------- 354

Query: 394 PTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIAT 453
           P+   Q +  L   P+V+ LL   +I   +   P+    +   K   A       Y I  
Sbjct: 355 PSRYKQALEILLKAPEVKNLL---IIHTPSALAPSEDYANIIVKTLQALPKMARPYVITN 411

Query: 454 VTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAV 513
            TG +              +  I    +   A      L+       +  T +   N   
Sbjct: 412 FTGEDA----AYAARRVCANNAIPTYRTPEGAVGAFMHLV-SYRRNQKHLTQTPESNTVD 466

Query: 514 INIGLRSFALELQS 527
             I   +    +  
Sbjct: 467 TKINKSAAKALVNE 480


>UniRef50_Q0W3R5 Acetyl-coa synthetase (ADP-forming), alpha subunit n=2
           Tax=Euryarchaeota RepID=Q0W3R5_UNCMA
          Length = 460

 Score =  250 bits (637), Expect = 1e-64,   Method: Composition-based stats.
 Identities = 66/458 (14%), Positives = 130/458 (28%), Gaps = 55/458 (12%)

Query: 66  VAIRSEAADAGI-AQAIMQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   + D       ++  +     +      + S+Q +   + +        + +L +
Sbjct: 15  IAVIGASKDQSKWGYKVLYNILSNRYKGKVFPVNPSAQEILGKQCFPDVTSIPDEVDLGV 74

Query: 123 ISVAGEYAAELANQALDRNLNV-MMFSDNVTL------EDEIQLKTRAREKGLLVMGPDC 175
           + V  + A  + +    + +    + +   +         E  LK +A+  G+ ++GP+ 
Sbjct: 75  VIVPAQAAPSVIDDCGRKGVGALCVITSGFSEVGKEGAALEEDLKKKAKAYGMRMLGPNT 134

Query: 176 GTSMIAGTPLAFANVMP---EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
              +     L  + V      G I  I  SG     L      +  G+   I  G +   
Sbjct: 135 MGFVNRSISLNASIVPRMPYRGEISFISQSGALGLALTDWSIGSRLGLNCIISTGNK--- 191

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                +S    LE    DE +  ++   +   +  R   + A     KP +A+  G + A
Sbjct: 192 ---ADVSEADLLEYFDQDEDTWTISMYIEGLKDGRRF--IEAASKVKKPMLAIKAGVSQA 246

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRNAIAP--------------VSSGFICGLYT 338
            AR       S     A       +    R                        +  L  
Sbjct: 247 GARAAASHTGSLAGSDAVYDSAFRQCGVIRVEGVEEMFDAAMAVSTQPRPEGNRVAILSN 306

Query: 339 GGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI---DPT 395
           GG +A  A+               Q   +       I  L   F +V  P   +   D  
Sbjct: 307 GGGMAIMASDACERRG-------MQVPQLNKYTRAGIARLLPAFASVKNPVDTVAKSDYH 359

Query: 396 LRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVT 455
           +  + +  L     +  +++       A A    ++  A Q       +  P   +A   
Sbjct: 360 IYKEAMRALLDDKDIDCVMVIY-----AHAGMTDAMEPA-QAVVDMLKEKYPKPVVACWM 413

Query: 456 GTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
           G E                 +        A      LI
Sbjct: 414 GGE----DIDAVARMFRKNRVPFYPVPERAAEALRTLI 447


>UniRef50_Q2RLH5 CoA-binding n=1 Tax=Moorella thermoacetica ATCC 39073
           RepID=Q2RLH5_MOOTA
          Length = 707

 Score =  249 bits (636), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 74/471 (15%), Positives = 140/471 (29%), Gaps = 61/471 (12%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VAI   + +   A    ++ L E          +     +  +  + S         L +
Sbjct: 15  VAIVGASNNPDKASHQFLKTLIEERFTGDIFPVNPRETKVLGLDCYPSLKDVSGYVELVV 74

Query: 123 ISVAGEYAAELANQALDRN--LNVMMFSDNVT-------LEDEIQLKTRAREKGLLVMGP 173
           I++      E+  QA +R      ++ S           ++ E ++   AR  G+ V+GP
Sbjct: 75  IAIPAPGVPEVMRQAAERGDVKGAIIVSAGFAETAIPERVKLEKEVVAIARSAGIRVIGP 134

Query: 174 DCGTSMIAGTPLAFANV----MPEGNIGVIGASGTGIQELC--SQIALAGEGITHAIGLG 227
           +C   +     L+ +      M  GNIG    SG     +   +       G +    +G
Sbjct: 135 NCNGVINTENRLSTSFAPGLQMIPGNIGFFTQSGATGGSILMLTAAQPKPLGFSKWAHVG 194

Query: 228 GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFL 287
                  +  ++ L  LE  ++D   +V+A   +   +   L  +       KP + L +
Sbjct: 195 N------MCDVTNLEILEYYASDPSVKVIAGYMEGVRDGRELMRLAEKITRKKPLLVLKV 248

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARR--------------NAIAPVSSGFI 333
           G T   +R       +            ++    R                  P     +
Sbjct: 249 GRTEVGSRATLSHTGTLAGSDKIYDAAFTQSGIVRVDKLEELVDSAKVLVMAPPPRGNRV 308

Query: 334 CGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID 393
           C L   G L   A   +       +D   +   +       + ++      + +P+  ID
Sbjct: 309 CILTEAGGLGIIAMDEVG------SDPAVRLASLTPETQKALAEVLPPMAMICKPNGYID 362

Query: 394 PTL------RNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQP 447
            T         + +  +   P V  +LL   IG   T  PA  +  A             
Sbjct: 363 MTAAAMEREHAEALRLVLEDPNVDAVLL---IGLPPTFLPAERVAQAIAAVAKKYD---- 415

Query: 448 LYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSP 498
              +          +        LE+ GI    +   A      LI   + 
Sbjct: 416 KPVLVCFM----TGKAMEDGRRYLEERGIPTFDTPDRAARALINLIKAGNR 462


>UniRef50_Q979A5 Succinyl CoA synthetase alpha subunit n=2 Tax=Thermoplasma
           RepID=Q979A5_THEVO
          Length = 693

 Score =  249 bits (636), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 86/525 (16%), Positives = 164/525 (31%), Gaps = 54/525 (10%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGS--SQALTQVRRWDSACQKLPDANLAL 122
           VA+   + D       I++ L+E   +      +     +   + + S      + +LA+
Sbjct: 12  VAVIGASNDNTKIGYQIIRNLKEGGYKGKIYPINTKDGTILGYKAYPSILDVPDEVDLAI 71

Query: 123 ISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           +S+  +Y  + A +   + +  ++     FS+    + E QL    ++ G+ ++GP+   
Sbjct: 72  LSIPAKYTPQAAEECGRKGVFGIIVVASGFSEVGNKDLEDQLANTCKKYGVRLLGPNVVG 131

Query: 178 SMIAGTPLA--FANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSRE 234
            M     L   FA  +P  G IG+I  SG  I  L +       G +  I +G       
Sbjct: 132 LMNNVIKLNASFAPYLPYPGTIGMISQSGALIVGLDAMTWANKTGTSFLISIGN------ 185

Query: 235 VGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVA 294
           +  +     +  L+ DE    ++  ++      +   V+  +   KP V L  G +   +
Sbjct: 186 MADLDFSDLVTFLADDENVSCISLYAEGLKAGRKF--VDTARLINKPIVMLKSGVSKHGS 243

Query: 295 RDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHL 354
                   S           L +    R             L     +  +   ++    
Sbjct: 244 VAAASHTGSLAGSHRVYDGALKQAGVIRAYSIEELFDLSLTLSLQKPMKGDNLIVVTNGG 303

Query: 355 GV---EADDTHQHGMMLDADSHQI----IDLGDDFYTVGRP---HPMIDPTLRNQLIADL 404
           G+     D     G+ L   S+ +      +   F +   P     M  P +    I  +
Sbjct: 304 GIGVLATDQAEASGLPLQTPSNDLQGKIKQIIPSFGSTKNPIDMSAMATPQIYADTIKTV 363

Query: 405 GAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCR 464
                V  L+  V+    A  DP+ +              N+ +  +A   G E      
Sbjct: 364 MEDESVDGLV--VLYCEVANLDPSDAAKGIIN---GVLSSNRKIPVVAGFVGGENSIN-- 416

Query: 465 SQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQ----QHTPSLL-------ENVAV 513
                 L   GI    S  +A    +AL                PS L       E    
Sbjct: 417 --ASLYLIKNGIPTFDSPDKAVKAISALRKHQQMNDLICVGPERPSDLKKDGIGSELKKY 474

Query: 514 INIGLRSFALE-----LQSASKPVVHYQWSPVAGGNKKLARLLER 553
           I  G++S +              V   + +       K+A+  + 
Sbjct: 475 IEAGVKSLSELESKKIFSEYGINVNKTELARSKDDLMKIAQEFKY 519


>UniRef50_C0QHB0 SucD4 n=1 Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QHB0_DESAH
          Length = 897

 Score =  249 bits (635), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 73/536 (13%), Positives = 141/536 (26%), Gaps = 69/536 (12%)

Query: 66  VAIRSEAADAGIAQAIMQ-QLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +   G    ++   L  A  +      S   + +  V+ +          +LA+
Sbjct: 15  VALIGASQTPGTIGRVVAGNLFSAGFKGEIFPVSTEFKTIEGVKTYPDVASLPRAPDLAV 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-SDNV-----TLEDE--IQLKTRAREKGLLVMGPD 174
           I    +   E+  Q   R     +  +D           E  + +   AR     ++GP 
Sbjct: 75  IVTPPDTIPEMIAQLGKRGTRAAVVLTDGFTNDTDPHHQELNMAMLAAARPHLFRIVGPS 134

Query: 175 CGTSMIAGTPLAFANVMPE---GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
               M+ G  L  +        GN+ ++  SGT +  +       G G +  + LG    
Sbjct: 135 SLGVMVPGIGLNASFGHAPPLSGNLALVAQSGTVLTAVLDWGTSQGIGFSKCVALG---- 190

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
             E+        L+ L+ D  ++ +    +    A +        A  KP + +  G   
Sbjct: 191 --EMADGDFGDMLDYLAYDYSTQAILLYIEEITGARKFISAARAVARIKPVIVVKAGRHG 248

Query: 292 AVARDENVWFASSLDEAARLACLLSRVTARR--------------NAIAPVSSGFICGLY 337
                            A       R    R                   VS   +  L 
Sbjct: 249 ENVLAPASHTGFPTGSDAFYDAAFRRTGMLRVKDMQALFNAVQTLAVARRVSGNRLAILT 308

Query: 338 TGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID---P 394
            G ++   A   L    G  A          +        +    ++ G P  +++    
Sbjct: 309 NGRSMGVMATDTLIDRGGQLAVLGPDTLDRFN-------QILPSAWSHGNPVNIMNDAPG 361

Query: 395 TLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATV 454
           +     +  L        +L  V+    A A    +  +                 +   
Sbjct: 362 SRYGDALEALANDTGTDAVL--VINCPSAVASSTEASNAVINTLQDKISTYNRKLVLTCW 419

Query: 455 TGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA----------QQHT 504
            G E       +      +  I   ++  EA      ++                 +  T
Sbjct: 420 IGNE----SALEARRIFTENRIPTYTTPAEAVRGFMQIVRYHKSQEMLMETPPNIPEVFT 475

Query: 505 PSLLENVAVINIGL---------RSFALELQSASKPVVHYQWSPVAGGNKKLARLL 551
           P       +I+  L               L + + PVV    +        LA  +
Sbjct: 476 PDSATAQKIIDGALAENRSWLTVSEAMAVLAAYAIPVVATHEASSPEAAAGLAETI 531


>UniRef50_Q64CM7 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           GZfos1D1 RepID=Q64CM7_9ARCH
          Length = 448

 Score =  247 bits (630), Expect = 8e-64,   Method: Composition-based stats.
 Identities = 67/467 (14%), Positives = 139/467 (29%), Gaps = 59/467 (12%)

Query: 66  VAIRSEAA-DAGIAQAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   ++        I+  +            + +   +  +R + S        +L +
Sbjct: 11  IAVIGASSNREKWGYRILDNIISGGYSGEVYPVNPNEDEVLGMRCYPSVLDLPHRVDLGI 70

Query: 123 ISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           I+V  E    +  +   + +  ++     FS+    E E ++   AR+  + ++GP+   
Sbjct: 71  IAVPAEIVPAVLEECGRKGIRGVVIVSAGFSEIGNSELENKVSDIARDYEMRMIGPNTFG 130

Query: 178 SMIAGTPLAFANVMP-E--GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSRE 234
            +     L  + +      G I  +  SGT    L    A    G+   +G+G +     
Sbjct: 131 FINTHLNLNASIIPQMPVIGGISFVTQSGTFGLALVDWAASQQMGLHLVVGVGNK----- 185

Query: 235 VGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVA 294
              +     L  LSAD  ++ +    +        + ++      KP +AL  G + A +
Sbjct: 186 -ADVDDSDILAYLSADRHTKTIMMYIEGI--ERGRRFIDVASRIRKPVIALKTGRSLAGS 242

Query: 295 RDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLY----------------T 338
           +       S             +    R             L                  
Sbjct: 243 KAVLSHTGSLAGTDRIYDGAFKQAGVIRAWTIEELFDSALALSISPPAGDGIGIISNGGG 302

Query: 339 GGTLAAEAAGLLAGHLGVEADDTHQ---HGMMLDADSHQIIDLGDDFYTVGRPHPMIDPT 395
              LAA+    L  HL   +DDT +     +   A     +D   D              
Sbjct: 303 AAILAADLCEDLGLHLPDMSDDTVRMLKGVLPAIATPANPLDTAGDA----------SYE 352

Query: 396 LRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVT 455
           +   ++  + + P +  LL+  V      A+     + A  +A            I +  
Sbjct: 353 MFRDVVDIVLSDPGINALLVIYV-----HAEMVDPCLPA--EAVIDARKGCGKPVITSWI 405

Query: 456 GTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQ 502
           G     +     +  LE+  I        A +    L+       ++
Sbjct: 406 GG----KGLETAVQRLEENRIPNYPLPERAVVALNNLVRYKRILKKR 448


>UniRef50_C0QAQ8 SucC4 n=1 Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QAQ8_DESAH
          Length = 892

 Score =  246 bits (628), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 69/543 (12%), Positives = 149/543 (27%), Gaps = 81/543 (14%)

Query: 62  NDICVAIRSEAADAGIAQA-IMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDA 118
           N   +A+   +   G     IM+ L E   +      + + + +  +  + +      + 
Sbjct: 11  NAASIAVIGASERKGSVGESIMKNLVEKGYKGNIYPVNPNHKTIMGITAFPNVGAINRET 70

Query: 119 NLALISVAGEYAAELANQALDRNL-NVMMFSDNV------TLEDEIQLKTRAREKGLLVM 171
           +LA+++     A E+       ++   ++ S          +  E  +   A+  G+ V+
Sbjct: 71  DLAVVATPIAMAPEIVADCAKASIAGCVVISAGGKETGAPGVAIERSILDAAKPSGIRVI 130

Query: 172 GPDCGTSMIAGTPLA--FANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
           GP+C   +     L   FA+ +P  G I  +  SG     +         G +H + LG 
Sbjct: 131 GPNCLGIINTAVNLNASFAHQLPLPGRIAFLSQSGAVCTSVLDLAMREKVGFSHFVSLG- 189

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG 288
                 +  +     ++ L   ++ + +    +               +  KP +AL  G
Sbjct: 190 -----SMADVDFADMIDYLGTIKEVDSIVMYVENITNIRNFMSAARSVSRIKPIIALKSG 244

Query: 289 YTPAVARDENVWFASSLDEAARLACLLSRVTARR--------------NAIAPVSSGFIC 334
            + A AR       +   + A       R    R                +     G + 
Sbjct: 245 RSAAGARAAASHTGAMAGDDAIYDAAFRRAGILRVNDFEELFDCAEFLAKLQRPKGGRLA 304

Query: 335 GLYTG---GTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSH---QIIDLGDDFYTVGRP 388
            +      G +A +A         + + +T      +          +D+  D       
Sbjct: 305 VVSNAGGPGVMAVDALERQGVEPALLSRETLSKLDAILPQGWSRQNPVDILGDT------ 358

Query: 389 HPMIDPTLRNQLIADLGAKPQVRVLLLDV-VIGFGATADPAASLVSAWQKACAARLDNQP 447
                P    +         +   LLL    +G       A  L    +++         
Sbjct: 359 ----SPEQYMEAARICIEAEETDGLLLIFAPVGLFDATTLATPLAQFLKES--------T 406

Query: 448 LYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSP--------- 498
                   G         +      +AG+    S          L    +          
Sbjct: 407 FPVFTAWMGGTN----IDKARKIFNEAGVVTYDSPERGVRAFMNLYRYGNNLDMLNEIPI 462

Query: 499 ------AAQQHTPSLLENVAVINIGLRS----FALELQSASKPVVHYQWSPVAGGNKKLA 548
                    +   + +   A+    +          L++   PV     +  A    +LA
Sbjct: 463 RRDRRLLIDRERAAGIIKAALAENNMEFTEVEAKDLLRAYGIPVNACLLAETADKAAELA 522

Query: 549 RLL 551
             +
Sbjct: 523 GQM 525


>UniRef50_C5U6W7 CoA-binding domain protein n=1 Tax=Methanocaldococcus infernus ME
           RepID=C5U6W7_9EURY
          Length = 667

 Score =  246 bits (627), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 72/459 (15%), Positives = 149/459 (32%), Gaps = 56/459 (12%)

Query: 62  NDICVAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           N   +AI       G A  +I++ L +   +L   +     +  ++ + S        +L
Sbjct: 3   NPKAIAIIGATPKEGKAGYSILKNLLKFKGKLYPINPKYSEIFGIKCYKSILDVDDKIDL 62

Query: 121 ALISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGPDC 175
           A+I V      ++  +   + +  ++     FS+   +E E +++   ++  +  +GP+C
Sbjct: 63  AIIVVPNVVVPQVLEECGKKGVKYVVIISAGFSEVGNVELENKVRGILKKYNIRAIGPNC 122

Query: 176 GTSMIAGTPLA--FANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
              + A   L   F+ V P +GNI +I  SG  I  +   + L   G++  + LG +   
Sbjct: 123 FGLINAHINLNATFSKVFPEKGNISLISQSGAVIDAILDILPLLNIGVSKVVSLGNK--- 179

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                I     LE+L  DE++ V+    +   +      V    A  KP + L  G + A
Sbjct: 180 ---IDIQESDILEILKDDEETRVIGIYLESLKDKN-FLKVAKEVAKKKPIIVLKAGKSEA 235

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRNAIAPV---------SSGFICGLYTG---- 339
             R       +   E      +  +                    +   + G   G    
Sbjct: 236 GKRAAKSHTGALAGENELYEAIFKQCGFIITETFEEFVDALHVFSTQPEMRGNKVGIITN 295

Query: 340 ----GTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPT 395
               G LAA+A+      L   +       ++ +A+    +D+  D            P 
Sbjct: 296 AGGFGVLAADASESYNLELPEFSVKEELKEVLKNANISNPLDIIGDAT----------PE 345

Query: 396 LRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVT 455
              +++  +     +   L  +++       P        + A       +    + +  
Sbjct: 346 RYEKVVKIVMKDKNMDGYL--IILTPQEMTKP-------LEVAEKLVRVEKVKPLVTSFI 396

Query: 456 GTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH 494
           G            + L   GI    +        + L  
Sbjct: 397 GG----VSVKGAKSFLRKHGIPSYITPENGVKALSNLYK 431


>UniRef50_B1L7G3 Acyl-CoA synthetase (NDP forming) n=1 Tax=Candidatus Korarchaeum
           cryptofilum OPF8 RepID=B1L7G3_KORCO
          Length = 459

 Score =  245 bits (626), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 74/467 (15%), Positives = 156/467 (33%), Gaps = 60/467 (12%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQLAQG--SGSSQALTQVRRWDSACQKLPDANLAL 122
           VAI   +         I++++ E   +      + ++  +  ++ + S        +L +
Sbjct: 12  VAIVGASRSEEKVGHVILRRMVEIGFEGKIYPINPNADEILGIKCYKSISDIPESVDLVV 71

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTL----EDEIQLKTRAREKGLLVMGPDCGT 177
           ++V  +    +  +A D+     ++ S   +     E E +L   AR++G+ V+GP+C  
Sbjct: 72  VAVRADATPAVIEEAADKGARGALVISGGFSEVGNWELERKLVEVARKRGIRVIGPNCLG 131

Query: 178 SMIAGTPLAFANVMPE-------GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
                  +    +          G I VI  SG+    + + +   G GI+  +  G R 
Sbjct: 132 IFDPKDKIDTLFLPERVIPRPGEGKIAVITQSGSLGSTVLTMMRKEGMGISKFVSYGNR- 190

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
                  +     LE L  DE ++V+A   +  A+  +        +  KP V L  G T
Sbjct: 191 -----ADVDEGELLEYLMEDEDTQVIAAYIESVADGRKFMESMRRASRRKPVVVLKGGKT 245

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARRNAIA--------------PVSSGFICGL 336
            +  R       S    +      + +      +                P+S   +  +
Sbjct: 246 SSGDRAVRSHTGSMAGSSEIFHSAVKQSGGIVVSSLGEFLDSTQTLVSQPPMSGDRVAVI 305

Query: 337 YTG---GTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID 393
             G   G LA +A   +   L   ++   +           + ++   +Y VG P  +  
Sbjct: 306 TNGGGFGILAVDALESIGFRLNPPSERLERK----------LREILPPYYPVGNPTDLTG 355

Query: 394 ---PTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYA 450
              P    ++ +      +   L +  ++G  A       +     KA +  L +  +  
Sbjct: 356 DSTPEQFLEVGSIFSESGEYDALFIIPLLGVPAM------IPDRTLKALSELLKSSKIPI 409

Query: 451 IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLS 497
           +A    T  +       +  L+  G+ V  +   A     +L     
Sbjct: 410 VAVAVPTTDEVDSI---LRELKRRGLPVFPTPERAAYSLLSLKKYGE 453


>UniRef50_B5YGW4 Acetyl-CoA synthetase n=1 Tax=Thermodesulfovibrio yellowstonii DSM
           11347 RepID=B5YGW4_THEYD
          Length = 898

 Score =  245 bits (626), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 68/520 (13%), Positives = 135/520 (25%), Gaps = 78/520 (15%)

Query: 66  VAIRSEAADAGIAQ-AIMQQL--EEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+       G     + + L  EE    +   +  S ++  V  +        + +L +
Sbjct: 15  IAVIGADNTPGTIGYTVFRNLIGEEYKGIVYPVNPKSDSVQGVEAYKRLNDISKEIDLVV 74

Query: 123 ISVA-GEYAAELANQALDRNLNVMM--FSDNV-----TLEDEIQLKTRAREKGLLVMGPD 174
           ++   G    ++  +   +    ++    D        +  E +++   R+ G  ++GP+
Sbjct: 75  LAEECGGNVLDILEECGQKGAKGVILLCPDFRTKVKEAMHLEEKIEEIHRKYGFRLLGPN 134

Query: 175 CGTSMIAGTPLA---FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
               +  G  L    F   + +GNI +I  S T    L  + A    G ++ + LG    
Sbjct: 135 SLGFIRPGINLNVSLFRRKLNKGNIALIAQSATLSVALLDRAADKNIGFSYFVSLGSD-- 192

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
                 I     ++    D  +  +    +      +        A  KP V +  G   
Sbjct: 193 ----IDIDFADLIDFFGVDPSTRAIVIYMQSIKNGRKFMTSARSFAFSKPIVIVKSGKFV 248

Query: 292 AVARDENVWFASSLDEAARLACLLSRVTARRN--------------AIAPVSSGFICGLY 337
                          E         R  A R                        +  + 
Sbjct: 249 ESLEVALTHSGLLAGEDKVYDTAFKRAGAVRVDETLDMFYITETLSKQRRPRGKRLAIIT 308

Query: 338 TGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADS-----HQIIDLGDDFYTVGRPHPMI 392
             G  A  A   L    G  A+ + +    L+           +DL  D           
Sbjct: 309 NAGAPAVSAVDSLIKLEGELAEFSQETVKELEGIVPARIIRNPLDLVSDA---------- 358

Query: 393 DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIA 452
            P      +  +     V   L+      G         V   Q+      +N     + 
Sbjct: 359 KPEDYENALKIIIKDKNVDGALIMFTPSLGTQP------VETAQRVIKIVKENPYKPVLT 412

Query: 453 TVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH-PLSPAAQQHTPS----- 506
              G        ++    L   GI    +  +A      +     +      TP      
Sbjct: 413 NWMGAAL----VNEARELLNSHGIPTFVTPEQAVRTFMYMYRYDFNLKLLLETPQTILKD 468

Query: 507 ----LLENVAVINIGLR---------SFALELQSASKPVV 533
                     +I   +            +  L +   PV+
Sbjct: 469 VTFNAERAAEIIERAISEGRSIPTFFEASEILSAYGIPVI 508


>UniRef50_Q2NFU6 Predicted acyl-CoA synthetase n=4 Tax=Methanobacteriaceae
           RepID=Q2NFU6_METST
          Length = 700

 Score =  245 bits (626), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 66/469 (14%), Positives = 146/469 (31%), Gaps = 64/469 (13%)

Query: 62  NDICVAIRSEAADAGIAQAIMQ-QLEEALKQLAQGSGSSQA---LTQVRRWDSACQKLPD 117
           N   +A+   ++  G    I+   L E          +++    L  +  + +  +   D
Sbjct: 9   NPKSIAVIGASSQEGKVGYIITTNLIECGYGGNIYPVNTKTDGKLLGLPAYKTVSEIDDD 68

Query: 118 -ANLALISVAGEYAAELANQALDRNLN-VMMFSDNV------TLEDEIQLKTRAREKGLL 169
             +LA+IS+   +  +   +   + +  +++ +           + E ++   A++  + 
Sbjct: 69  NIDLAVISIPARFINQTLEECGQKGIKNIIVITAGFKEVGGEGAKLEDEMAEIAKKYDMN 128

Query: 170 VMGPDCGTSMIAGTPLAFANV---MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGL 226
           + GP+C  S+   TP+  +       +GNI  +  SG     +       G G +  + L
Sbjct: 129 IQGPNCLGSLDTNTPMNASFAQLSPKKGNIAFVSQSGAMTVAILDWSVSEGIGFSKVVSL 188

Query: 227 GGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALF 286
           G +        +S +  +E L+ D++++V+    +  ++  R   V       KP V L 
Sbjct: 189 GNK------VDVSEIDLIEYLATDDQTKVILCYLEGISDGERFLEVMRRVTKIKPVVILK 242

Query: 287 LGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGF-------------- 332
            G + A A+  +    +     +            R         +              
Sbjct: 243 AGSSQAGAKAVSSHTGALAGNDSAFDAAFENCGVMRARSMNDLFDYGLAFSKSSLPTGKK 302

Query: 333 ---ICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHG----MMLDADSHQIIDLGDDFYTV 385
              I     GG L A+    +   L    D T            +  + I  LGD     
Sbjct: 303 VAVITNAGGGGVLTADKIEDIGLELVDLTDQTKSELRAVIPDEGSVENPIDVLGDAPADR 362

Query: 386 GRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDN 445
                          +  L  +  +  +++         ++      +A  +A       
Sbjct: 363 -----------YKATLDILLEEDDIDSIIIMACPTASYDSEGVG---NAIVEAKGKTD-- 406

Query: 446 QPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH 494
             +  +    G        +++   L +  I V      A  +  AL  
Sbjct: 407 --IPILVVNMGGP----TFNEENILLRENNIPVCVFPETAVNVLKALER 449


>UniRef50_B5IDQ5 CoA binding domain protein n=2 Tax=Aciduliprofundum boonei T469
           RepID=B5IDQ5_9EURY
          Length = 464

 Score =  245 bits (624), Expect = 5e-63,   Method: Composition-based stats.
 Identities = 65/474 (13%), Positives = 145/474 (30%), Gaps = 49/474 (10%)

Query: 57  NNATPNDICVAIRSEAADAGIAQ-AIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQ 113
              +P+   +A+   ++        +++ L+           +     +   + + S   
Sbjct: 4   KLISPDS--IAVVGASSHPNKIGYVVLENLKNNGYGGRIYPVNPKGGQILGFKVYPSIND 61

Query: 114 KLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNVTL------EDEIQLKTRAREKG 167
              + +L++I++  E   ++      ++  ++  +           E E ++   A++  
Sbjct: 62  VPEEVDLSVITLPAEVTVKIFEDVAKKSKFIIPIAGGFGETGKEGKERERKILEIAKKYN 121

Query: 168 LLVMGPDCGTSMIAGTPLAFANVMPE-------GNIGVIGASGTGIQELCSQIALAGEGI 220
             ++GP+     I  T +  A V+PE       G+I  I  SG         +++   G 
Sbjct: 122 ARIIGPNTVGIYIPSTGVNTALVVPERSRFPGDGDIAFITQSGALGLLTMDSVSMYDVGF 181

Query: 221 THAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGK 280
           +  I LG R        ++    L+    DEKS+V+    +  A       V    +  K
Sbjct: 182 SSFINLGNR------VDVNENELLQYFGEDEKSKVIIMYIESFANGREFMRVAKNVSRKK 235

Query: 281 PTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGG 340
           P V L  G T    +  ++   +     A       +    R         +   L  G 
Sbjct: 236 PIVVLKAGRTKRGGKAASLHTGALGGSDAVADGAFKQCGVIRAYDEIELVDYARALAYGK 295

Query: 341 TLAAEAAGLLAGHLG--------VEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI 392
            +  +   ++    G        +E++       M +        + D+          +
Sbjct: 296 PIEGDRIAVVTSAGGVGVVTTDYIESEVRGIGMKMAELSDEIKRRIRDEVVPFASVENPV 355

Query: 393 DPTL------RNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQ 446
           D T        + ++A L   P V  +L+     +     P   +               
Sbjct: 356 DMTAQASDDDYDGVLAALNDDPNVDAILV-----YALFQTPL--ISEKLVNIITKWHREG 408

Query: 447 PLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
               +    G+E       + +   ED  + V  S+  +      L +      
Sbjct: 409 DKPIVVGTIGSEFAL----RMMRKFEDNKVPVYPSIERSVKALRVLRYRAKLLE 458


>UniRef50_B8D575 AcdA-1 acetate--coA ligase (ADP-forming), alpha chain n=1
           Tax=Desulfurococcus kamchatkensis 1221n
           RepID=B8D575_DESK1
          Length = 481

 Score =  243 bits (619), Expect = 2e-62,   Method: Composition-based stats.
 Identities = 64/475 (13%), Positives = 134/475 (28%), Gaps = 66/475 (13%)

Query: 62  NDICVAIRSEAADAGIAQAIMQQ--LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDAN 119
           N   VAI       G    I+ +  +++   ++   +     +  ++ + S  +     +
Sbjct: 24  NPRSVAIVGATPKEGKVGRIILENFIKKYKGRIYPVNPGYNEIMGLKCYRSVSELPETPD 83

Query: 120 LALISVAGEYAAELANQALDRNLNVMMFSDNV--------TLEDEIQLKTRAREKGLLVM 171
           LA+I V      E+  +  ++    ++                 E ++K  A + G+ ++
Sbjct: 84  LAIIVVPAPSVPEVLRELGEKGCKAVIIISGGFKETGTPEGERLEHEIKELAVKYGIRII 143

Query: 172 GPDCGTSMIAGTPLAF-------ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           GP+C       + +             P+G +  I  SG     L   +A    G++ AI
Sbjct: 144 GPNCIGIFDNWSGVDTFFLPEEKMKRPPKGYVAFISQSGAFASALMDWMAYNNIGVSRAI 203

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVR--LKIVNAMKATGKPT 282
             G +        +  +  LE L+ D+K+ V+    +    A            +  KP 
Sbjct: 204 SYGNK------IDVDDIDLLEYLAGDDKTRVILVYLEGLKNARGRIFIETARRVSRVKPV 257

Query: 283 VALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTG--- 339
           +    G T   +       A+     +       +               +  L      
Sbjct: 258 LVFKAGKTSRGSLAAASHTAALAGNYSLYRSAFKQAGVIEVESFDEMMDAVRILLDQPLM 317

Query: 340 --------------GTLAAEAAGLLAGHLGVEADD---THQHGMMLDADSHQIIDLGDDF 382
                         G +  +A  +    L     D     +  +         IDL  D 
Sbjct: 318 NGNRVYVVTDAGGVGVMLTDALTVQGFELPRTPPDLKEELRKILPPHCIVENPIDLTGDT 377

Query: 383 YTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAAR 442
                     D     +++  +  +  V  +++  +            L     +A    
Sbjct: 378 ----------DDERYIKVLEKVLPRSDVDAVVVVALPQV---PGIKGGLADYLIEAKNKY 424

Query: 443 LDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLS 497
           +       I    G E       +    L++ G+ V  S   A      L     
Sbjct: 425 M----KPVIVISIGGEE----AIKLARKLQENGVTVFESPERAAKALKVLYTYSR 471


>UniRef50_Q30WE4 Acetyltransferase, GNAT family n=4 Tax=Desulfovibrio
           RepID=Q30WE4_DESDG
          Length = 911

 Score =  242 bits (618), Expect = 2e-62,   Method: Composition-based stats.
 Identities = 69/542 (12%), Positives = 144/542 (26%), Gaps = 82/542 (15%)

Query: 66  VAIRSEAADAGIAQAIMQQ---LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+       G    I+ +       L  +   + + + +  +  +          +LA+
Sbjct: 15  IAVIGATDTPGQPGRIVMENLLKGAFLGPVLPVNETREPVMGLESYSEIDTLPITPDLAI 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNV--------TLEDEIQLKTRAREKGLLVMGPD 174
           I    +       +   R     +   +                +   A+  G+ ++GP+
Sbjct: 75  ICTDADSTPFYLAELGKRGTQAAVLLSHGYFRFDRDRREVQRATVMDIAQAHGMRILGPN 134

Query: 175 CGTSMIAGTPLAFANVMP---EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
           C   +     +  +        G I  +  S +    +       G G +H I LG R  
Sbjct: 135 CLGFINPSVGVNASLAHREALPGRIAFVSQSDSLFTSVLDWATSKGVGFSHFISLGDRY- 193

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
                 I+    L+ L+ D  +  +    +  + A R        A  KP + +  G + 
Sbjct: 194 -----DINFADILDYLNNDPGTRAVLLYLETISGARRFMSAARALARNKPVLVMKSGKSE 248

Query: 292 AVARDENVWFASSLDEAARLACLLSRVTARR--------------NAIAPVSSGFICGLY 337
           A A                      R    R                 AP+    +  L 
Sbjct: 249 ASATAAAAHSGMPPGSDDVYDTAFRRAGMLRVFDIDSLFDTVETLARAAPLKGDRLAILT 308

Query: 338 TGGT---LAAEAAGLLAGHLGVEADDTHQHGMML----DADSHQIIDLGDDFYTVGRPHP 390
            GG    LA +A     G L   +++T Q          +  + ++              
Sbjct: 309 NGGGPGFLATDALLAGGGRLAELSEETCQTLDNELKGDWSYWNPLVIKSG---------- 358

Query: 391 MIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYA 450
             D  +  + +  L     +  +L+  V    A +           +             
Sbjct: 359 -ADADMYARTLKVLLDDKSLDAVLVMHVPSIYADS-------GQVAEGVVRACRRTKKAV 410

Query: 451 IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLS--------PAAQQ 502
           + +  G +      +   +T   AG+    +   A      L+            P +  
Sbjct: 411 LTSWLGID----DAAGARSTFRKAGLPSFFTPDNAVRAFLNLVQYRRNQDLLVEAPPSLP 466

Query: 503 HTPSLLENVA--VINIGLRSFALE---------LQSASKPVVHYQWSPVAGGNKKLARLL 551
            T     + A  V+N  L               L++    +   +  P      + A  +
Sbjct: 467 DTFQPDVSRARLVVNEALDQQRQVLTVAETTGILKAYGINIPETRTVPDVHAAVRAAEEM 526

Query: 552 ER 553
             
Sbjct: 527 GY 528


>UniRef50_Q0HVJ0 CoA-binding domain protein n=113 Tax=Bacteria RepID=Q0HVJ0_SHESR
          Length = 913

 Score =  238 bits (608), Expect = 3e-61,   Method: Composition-based stats.
 Identities = 64/481 (13%), Positives = 127/481 (26%), Gaps = 62/481 (12%)

Query: 66  VAIRSEAADAGIAQAIM-QQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VAI   +     A  ++ + L  +         +   +A+  V  + +        +LA+
Sbjct: 24  VAIIGASNSEKRAGNVLMKNLLSSGFSGPIMPVTPKYRAVMGVLAYPNIEALPIKPDLAV 83

Query: 123 ISVAGEYAAELANQALDRNLNVMMF----------SDNVTLEDEIQLKTRAREKGLLVMG 172
           I         +          V +            + V+L D       A+  G+ ++G
Sbjct: 84  ICTRASRVPAIVETLAQFGCKVAIIMASGMAQEVNEEGVSLLDLA--MQHAKRYGMRILG 141

Query: 173 PDCGTSMIAGTPLAFANVMP---EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
           P+    ++    L  +        G I  +  S      +       G G +  I LG  
Sbjct: 142 PNSLGMLLPPLGLNASLAHASALPGKIAFVSQSAAICTTVLDWANNKGIGFSSFISLG-- 199

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
               +   I+    L+ L  D ++  +        E           +  KP + +  G 
Sbjct: 200 ----DATDINFDELLDFLGRDSRTSAIMLYIDSVNEKRHFLSAARAASRNKPILVIKSGR 255

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARR--------------NAIAPVSSGFICG 335
           +    R   +         A       R    R                  P+    +  
Sbjct: 256 SAEGVRAAKLHTGGIGGNDAVYEAAFRRAGMLRVNDLIELFAAVESLAHSNPLQGERLGI 315

Query: 336 LYTGG---TLAAEAAGLLAGHLGVEADDTHQHGM---MLDADSHQIIDLGDDFYTVGRPH 389
           +  GG    LA +   L  G L   + +T                 +D+  D        
Sbjct: 316 ISNGGGPAVLAVDELILRGGKLAELSPETIAKLDVVLPNTWSKQNPVDIIGDANA----- 370

Query: 390 PMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLY 449
                +     +  L    ++  +L   V+   +    +  +  A  K   A      L 
Sbjct: 371 -----SRYASALNILMDCEELDAIL---VLHSPSALGESVEIADALIKVIHAHPKKNRLN 422

Query: 450 AIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA-QQHTPSLL 508
            +   +G +   Q            GI+   +   A      ++         Q  P  +
Sbjct: 423 ILTNWSGEDSAYQ----ARKRFTKGGISTYRTPEGAVGAFMHMVEYRRNQKLLQEVPQSI 478

Query: 509 E 509
            
Sbjct: 479 P 479


>UniRef50_C1DBF7 Probable acetyl-CoA synthetase n=1 Tax=Laribacter hongkongensis
           HLHK9 RepID=C1DBF7_LARHH
          Length = 897

 Score =  238 bits (608), Expect = 3e-61,   Method: Composition-based stats.
 Identities = 68/495 (13%), Positives = 135/495 (27%), Gaps = 64/495 (12%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +   G    A+   L     +      + + + +  +    S        +LA+
Sbjct: 15  VAVIGASETPGSVGQAVFANLLAGGFKGRLYPVNLNHRVVGGMPAVSSVRSIEAPIDLAV 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLED------EIQLKTRAREKGLLVMGPDCG 176
           ++ A      +  +   + +  ++F+      D        +    ARE  + V+GP+  
Sbjct: 75  VTTAVRTWPGIMKECGKKGVKAVLFAKEFGDADPLAHEVMQESLAIAREYRIRVLGPNML 134

Query: 177 TSMIAGTPLAFAN---VMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
             M     L  +N    +  GN+ ++  S      +       G G T  I +G      
Sbjct: 135 GLMRPTIGLNASNYNGTVRAGNLALVSHSSALCAAMLDWADAKGIGFTSVISMG------ 188

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAV 293
           +   +     L+ L  D +++ +        +A R      M +  KP V +  G     
Sbjct: 189 DSVDLDFGEILDYLVYDNQTQGILLHLHHIHDARRFMSALRMASRTKPVVVIKSGRAAEP 248

Query: 294 --ARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTG------------ 339
                 +    +S D        L R    R             L               
Sbjct: 249 LSGVTTSSHLTASED---VYDAALERAGVLRVNTIAQLFTAARVLAANYRSQGDRLAIVT 305

Query: 340 -----GTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID- 393
                G LAA+AA  +   L   +D T Q             D+    ++ G P  ++  
Sbjct: 306 NGIGPGILAADAARAIGVELATLSDHTVQLFN----------DVLPSNWSRGNPVDIVGD 355

Query: 394 --PTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAI 451
             P      +      P V  +L+             A L+                  +
Sbjct: 356 ASPVRFRTAVKACLDDPNVDGVLVICTPQLSTDHLNTAQLM-------VDLRKESNKPLL 408

Query: 452 ATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENV 511
            +  G  +     +          +A   +   A  +  AL                   
Sbjct: 409 LSWLGDTK----VAASRELFVRHRVAHFRAPEAAVEVFRALAAFHRNQRLLLQTPPPLQF 464

Query: 512 AVINIGLRSFALELQ 526
             ++  +      ++
Sbjct: 465 EEVSADVAGARKLIR 479


>UniRef50_Q3AFE8 Acetyl-CoA synthase n=1 Tax=Carboxydothermus hydrogenoformans
           Z-2901 RepID=Q3AFE8_CARHZ
          Length = 716

 Score =  238 bits (607), Expect = 4e-61,   Method: Composition-based stats.
 Identities = 63/482 (13%), Positives = 135/482 (28%), Gaps = 40/482 (8%)

Query: 43  KALLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQ--LEEALKQLAQGSGSSQ 100
             +  T  F         P    +A+   +         + +  +     ++   +   +
Sbjct: 4   LKIAPTEKFKERVAKLLNPRS--IAVIGASEKPEKLGNAILRNIVSGYKGEVFGVNPRVK 61

Query: 101 ALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNV------TL 153
            + ++  +          +LA+I +  E A     +A +  +   ++ S           
Sbjct: 62  KIQEIEVYPDVFSLPYPVDLAVIVLPAEKAVVALKEAAEAGVKSAVVISGGFKETGNEGA 121

Query: 154 EDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELC 210
             E ++K  A +  + V+GP+C   +     L          +G I  +  SG  +  + 
Sbjct: 122 LLEEEIKKIALDFEMPVLGPNCVGIVNNNLQLNATFLRTAPLKGEIAFVSQSGAILSTVL 181

Query: 211 SQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK 270
                   G ++ I +G + +  E         L  ++ D  + V+    +   E     
Sbjct: 182 EWSLKEDLGFSYMISMGNKAVLNE------ADFLPAIANDPGTAVILLYIEDVVEGSSFL 235

Query: 271 IVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSS 330
                 +  KP V    G + A A+  +    +            ++    R        
Sbjct: 236 KKAYEASLLKPVVVFKAGISTAGAKAASSHTGALAGSIEGYKLAFAKTGLIRAKTLEEMF 295

Query: 331 GFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQH-GMMLDADS------HQIIDLGDDFY 383
            +     +G  +  +  G++    G       +     L+         +++        
Sbjct: 296 IYARVFASGQKVTGKNIGIVTNSGGPGVITADRLELNGLNITGLSAKTINELKTFLPRAA 355

Query: 384 TVGRPHPM---IDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACA 440
           + G P  +    D       +  +    +V  ++   V G  A  D         Q    
Sbjct: 356 SFGNPVDILGDADEEKYAMTLKTVLDDEKVDGVV--AVYGKTAVIDM----EKMVQAVIN 409

Query: 441 ARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
            R  N     +A   G         +    L    I   S    A    A L    S   
Sbjct: 410 GRRKNPDKPVVACFLGG----VDSRRAKELLNKNKIPFYSFPEAAADALAVLYRYYSWRE 465

Query: 501 QQ 502
           +Q
Sbjct: 466 KQ 467


>UniRef50_A2SRS8 CoA-binding domain protein n=2 Tax=Methanomicrobiales
           RepID=A2SRS8_METLZ
          Length = 707

 Score =  237 bits (605), Expect = 7e-61,   Method: Composition-based stats.
 Identities = 60/462 (12%), Positives = 134/462 (29%), Gaps = 62/462 (13%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
           VA+   + D      A+ + + +   ++   +     +  V+ + +        ++ +I+
Sbjct: 267 VAVIGASDDPTKMGYAVFRNILQFPGKVYPVNNKRDEIQGVKCYPTLSDIPGHVDMVVIT 326

Query: 125 VAGEYAAELANQALDRNLN-VMMFSDNVTLED------EIQLKTRAREKGLLVMGPDCGT 177
           V  +    + ++   + +   ++ +      D      E ++   A+  G+ ++GP+C  
Sbjct: 327 VPAQLVPAIMSECGLKGVKMAVVITAGFKEMDEDGRALETRMVEIAKNYGIRIVGPNCLG 386

Query: 178 SMIAGTPLAF---ANVMPEGNIGVIGASGTGIQELCSQIALAG--EGITHAIGLGGRDLS 232
            ++    L     +     G+I  I  SG  +  +       G   G +  + +G +   
Sbjct: 387 LILPPFKLDTTYVSTSPLPGDIAFISQSGAIVNAVVGISLSEGSEMGYSEVVSVGNQ--- 443

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                +  L  +   + D  ++ +    +     V    +       KP VA+  G +  
Sbjct: 444 ---CDLDFLDYMSYAARDPHTKSIILYVEEIKNGVAFMEMAKEITQTKPIVAIKAGSSKR 500

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRNAIA---------------PVSSGFICGLY 337
                     S             +                        P++      + 
Sbjct: 501 GQAAAASHTGSLSGSFDVYMEAFRKCGVVPVKTLPGAFQVAKALGDLKKPLTGRRAVVIT 560

Query: 338 TGGTLA------AEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPM 391
             G  A      AE  G+    L     D     +    + +  IDL  D  T  R   +
Sbjct: 561 NAGGFAVLSNDYAETWGIEIIDLPKHIIDELNTFLPPFWNKNNPIDLLGDA-TEARFRGV 619

Query: 392 IDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVS-AWQKACAARLDNQPLYA 450
            D   +N+ + D+        +L++          P   L      +             
Sbjct: 620 FDVLCKNEDLWDMA-------ILVNF---------PNKVLAPDRVAQILIDNSKRTDNLL 663

Query: 451 IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAAL 492
           + T  G +    C    +  L+   I V   L         L
Sbjct: 664 VGTFVGGD----CLKPGVDLLKKNNILVFEELEFTYRALGHL 701


>UniRef50_A8ZZJ4 CoA-binding domain protein n=2 Tax=Desulfobacteraceae
           RepID=A8ZZJ4_DESOH
          Length = 711

 Score =  237 bits (605), Expect = 7e-61,   Method: Composition-based stats.
 Identities = 77/542 (14%), Positives = 155/542 (28%), Gaps = 81/542 (14%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +   G     + + +            +  + ++  V+ + S  +     +LA+
Sbjct: 13  VAVLGASTTPGKVGHDLFENILRGRFNGTLYPVNPKADSILCVKAYPSLLEVPDAVDLAM 72

Query: 123 ISVAGEYAAELANQALDRNLNVMMFS-------DNVTLEDEIQLKTRAREKGLLVMGPDC 175
           I +  +      +  +++ +  ++              + E  +    R+ G+ V+GP+C
Sbjct: 73  IILPPKATLAAIHDCIEKKVKGVVIVSAGFREVGGEGKQIEESVAALCRKAGIRVVGPNC 132

Query: 176 GTSMIAGTPL----AFANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
              +   + +    +F+  MP +GNI  I  SG     +    +  G G +  I  G + 
Sbjct: 133 LGVINPNSKVRLNASFSRRMPSQGNISFISQSGALCTAVLDFASDMGVGFSKFISTGNK- 191

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPP-AEAVRLKIVNAMKATGK---PTVALF 286
                  +  L  L  L  D  ++V+    +                 + K   P +A+ 
Sbjct: 192 -----ADVDELDLLTYLHKDPATDVIMMYIEELKRGGQEFVDAVRKITSCKNPTPILAIK 246

Query: 287 LGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIA---------------PVSSG 331
            G T A A   +    S          + +     R                   P+   
Sbjct: 247 SGRTGAGAAAASSHTGSIAGSEGVYDAIFAETGIIRVDSVNELFDYAGAFATKKFPMGKR 306

Query: 332 FICGLYTGG-----TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVG 386
                  GG     T   E +GL       E  ++    +   A+ H  +D+  D     
Sbjct: 307 IAIVTNAGGPGIVATDMTEVSGLELARFSPETIESLASHLPPTANIHNPVDVIGDA---- 362

Query: 387 RPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQ 446
                 DP      +  +         L  V++   +  + A  +     K         
Sbjct: 363 ------DPERYQAALDAVIRDENTDSAL--VILTPQSMTN-AIKVARVISKIARR----T 409

Query: 447 PLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHP-----LSPAAQ 501
           P   +    G        S+ +  L++  I V      A    AAL            AQ
Sbjct: 410 PKPVVCAFMG----VIDVSEGVRHLQENHIPVYRFPENAAKAIAALYRSEQWVHRQYLAQ 465

Query: 502 QHTPSLLENVAVI----------NIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLL 551
                  +    I           +G       L      V+  + +        +A+ +
Sbjct: 466 FTFSHDKKRARQIFETCRQEGQTYLGELEGNEVLSCYGFSVLPTKLAETPEQAVAIAKEM 525

Query: 552 ER 553
             
Sbjct: 526 GY 527


>UniRef50_C5A3H6 Acetyl-CoA synthetase (ADP forming), alpha chain (AcdA) n=4
           Tax=Thermococcus RepID=C5A3H6_THEGJ
          Length = 537

 Score =  237 bits (604), Expect = 9e-61,   Method: Composition-based stats.
 Identities = 70/474 (14%), Positives = 137/474 (28%), Gaps = 57/474 (12%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQL---AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+        IA  I++ + E   +                 R ++   +     + A+
Sbjct: 12  VAVFGSFRKGAIAYEILRNIVEGGFEGKIIPVNPKGGSVEVAGRVFEIRERLDEPVDTAI 71

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTL----EDEIQLKTRAREKGLLVMGPDCGTS 178
           I++  ++   L ++   R    ++ S   +     + E +L  +AR+ G+ ++GP+C   
Sbjct: 72  IAIPAKFVPGLIDEIGPRIKGAVVISAGFSEVGNADLERELVEKARKHGVRLIGPNCAGI 131

Query: 179 MIAGTPL--AFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVG 236
                    +F   +  G + +I  SG       +     G G +  +  G         
Sbjct: 132 FGVHGKFFGSFEVRVKPGGLALISQSGAFGGAALAMGNEEGIGFSAFVSYGN------AA 185

Query: 237 GISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARD 296
            ++    LE  + DE ++ +A   +   +        +  +  KP + L  G + + A+ 
Sbjct: 186 DLNESDFLEYFADDENTKAIALYIEGVKDGRHFLKALSYASKRKPVIVLKAGKSASGAKA 245

Query: 297 ENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFIC--------------GLYTG--G 340
                 S             +  A                               +G  G
Sbjct: 246 AASHTGSLAGSYEIYRAAFKQAGAIEVEEMEELFDAAKAFEMYSMAGKRVAVITNSGGPG 305

Query: 341 TLAAEAAGLLAGHLGVEADDTHQHG---MMLDADSHQIIDLGDDFYTVGRPHPMIDPTLR 397
            LA +    L   +   ++DT       +     +   IDL  D           D    
Sbjct: 306 VLATDKLERLGLEIAKLSEDTVAKLQSFLPEQCSTRNPIDLIADA----------DYERY 355

Query: 398 NQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGT 457
            + I  +     V  +L   VI       P+  +  A  +A            I      
Sbjct: 356 KRTIEIVCRDGNVDSIL---VICVPPIFIPSEEIAKAVIEADCD------KPVIVNFMAG 406

Query: 458 ERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENV 511
           E         +  LE+  I    +   A    A L            P  L+ +
Sbjct: 407 EL----VRDGVKLLEEHSIKNFPTPERAARALAWLAMRKKRGGLILFPHPLKEL 456


>UniRef50_A3CY00 CoA-binding domain protein n=7 Tax=Methanomicrobiales
           RepID=A3CY00_METMJ
          Length = 707

 Score =  236 bits (603), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 70/491 (14%), Positives = 139/491 (28%), Gaps = 63/491 (12%)

Query: 47  DTTGFWHDDFNNATPNDIC----VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQA 101
           DT G          P D+     +A+   +A       ++++ L      L   + S   
Sbjct: 244 DTAGGAPARLRVRAPPDLFYPASIAVIGASASPNKVGYSVLRNLLSFPGNLYPVNPSRTE 303

Query: 102 LTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFS-------DNVTLE 154
           L   + + S        + A+++V      E+  +   + + + +               
Sbjct: 304 LFGRKTYPSVTGIPDPVDWAVVAVPARIVPEVMEECGKKGIRLAVIVTAGFREIGGEGTV 363

Query: 155 DEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFAN---VMPEGNIGVIGASGTGIQELCS 211
            E ++   AR  G+ ++GP+C   M+    +           G++  I  SG  I  +  
Sbjct: 364 LEEKVTAIARRHGIRIIGPNCLGIMMPHMGINATFDPVSPRPGDVAFISQSGAIITTVVD 423

Query: 212 QIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKI 271
                  G +  I +G +        +     L     DEK+  +    +   +      
Sbjct: 424 WSLPEEFGFSTVISVGNQ------ADLGFEHFLRFAEQDEKTRSVTLYVEEIQDGRGFMQ 477

Query: 272 VNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIA----- 326
           +    A  KP VA+  G +       +    S             +              
Sbjct: 478 IVGEVAKRKPVVAVKSGSSRKGRAAASSHTGSLAGSYDVYVAAFRQAGVIVARSLRDAFN 537

Query: 327 ----------PVSSGFICGLYTGG--TLAAEAAGLLAGHLGVEADDTHQHGM----MLDA 370
                     P     I     GG   LA++ A      +    DD  +           
Sbjct: 538 LAELLASEGYPKGKRAIAVTSAGGFAVLASDYAETYGVDMVDLPDDVLRELNAFLPPFWN 597

Query: 371 DSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAAS 430
            ++ +  LGD   T  R   + D  +R+Q   D+          + V+       DPA  
Sbjct: 598 HANPMDILGDADAT--RFAALFDVLIRHQNFWDI----------VFVIAVPTTLVDPAH- 644

Query: 431 LVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAA 490
                         N     +  + G +         +  L  + I     L +A     
Sbjct: 645 ----VANEIVRLSRNTEKMVVGCMLGGD----SIRSGLRILRGSRIPNFEELEDAFKAVG 696

Query: 491 ALIHPLSPAAQ 501
           +++   +   +
Sbjct: 697 SILEVGAVRQE 707


>UniRef50_B8D4Z1 Acetyl-CoA synthetase n=1 Tax=Desulfurococcus kamchatkensis 1221n
           RepID=B8D4Z1_DESK1
          Length = 471

 Score =  236 bits (601), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 62/470 (13%), Positives = 137/470 (29%), Gaps = 58/470 (12%)

Query: 66  VAIRSEAADAGIAQAI-MQQLEEALKQLAQGSGSS--QALTQVRRWDSACQKLPDANLAL 122
           +A+   +   G    I ++ ++    Q      +     +   + + S      + ++A+
Sbjct: 21  IAVIGASRTPGKIGYIVLRNIKGYGFQGKVYPINPHADEILGYKAYPSILDVPDEVDVAI 80

Query: 123 ISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           ++V  +   E+  ++  + + V +     FS+   +E E ++   AR+ G+ ++GP+   
Sbjct: 81  VTVPADNVPEVIEESGRKGVKVAVVITSGFSEVGNVELENKIVETARKYGMRILGPNIFG 140

Query: 178 SMIAGTPLAFAN---VMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSRE 234
            +   + +        +  G+I +I  SG     L     +   G++  + +G       
Sbjct: 141 YVYTPSNINATFGPLEVARGSIALISQSGALGIALMGWTIMNEIGLSALLSVGN------ 194

Query: 235 VGGISALTALEMLSADEKSEVLAFVSKPPAEAV--RLKIVNAMKATGKPTVALFLGYTPA 292
           +  +      E L+ D  + V+    +                    KP V +  G +  
Sbjct: 195 MADLDVAELSEYLADDPNTRVITIYLEGIKPGRGGEFIKKMREVTLKKPVVVIKAGRSRR 254

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFIC--------------GLYT 338
            A        S             +    R                           +  
Sbjct: 255 GAAAAASHTGSLAGSDNLYEAAFKQAGIIRAYTVEEMFDIARVFAAQPLPRGENTIIITN 314

Query: 339 G---GTLAAEAA---GLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI 392
           G   G LA +AA    +       E  +  +  M     +   +DL              
Sbjct: 315 GGGVGVLATDAAEFNDVKLLEPSQELKERLKTTMPWFGSAKNPVDLTGQAVV-------- 366

Query: 393 DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIA 452
                 + +       +V  ++  ++    A  DP   L  A  +      ++     +A
Sbjct: 367 --DNYVKALKIAAESSEVDNIV--ILYCRTAVLDP-RELAKAIVE--LYESEHISKTTVA 419

Query: 453 TVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQ 502
              G E       + I  L    I    S   A    + +I        +
Sbjct: 420 GFVGGE----DTYEAIKYLNRHDIPAYPSPERAVYALSKMIWYRRYLEAR 465


>UniRef50_O28761 Putative uncharacterized protein n=1 Tax=Archaeoglobus fulgidus
           RepID=O28761_ARCFU
          Length = 881

 Score =  235 bits (600), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 66/482 (13%), Positives = 149/482 (30%), Gaps = 61/482 (12%)

Query: 62  NDICVAIRSEAAD-AGIAQAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDA 118
           N   VA+   + D   +       L            + +++A+  VR + +  +   + 
Sbjct: 196 NPESVAVIGASRDVEKVGGRTFYNLLTYRFNGVAYPVNRAAKAIMGVRAYPTISEVPDEV 255

Query: 119 NLALISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVM 171
            LA++SV  +YA E+A +   + +  ++             +E + +L    R+ G+ ++
Sbjct: 256 ELAVLSVPVKYALEVAEECGKKGVKALLVLTAGFAEVGGEGVERQKKLVEICRKYGMRLI 315

Query: 172 GPDCGTSMIAGTPLAFANVMPE-----GNIGVIGASGTGIQELCSQIALAGEGITHAIGL 226
           GP+C   +                   G+I     SG     L  ++   G G+++ + L
Sbjct: 316 GPNCMGIINTAPETRLLATFAPTPPNEGSIAFASQSGAVGLALMDRVNNYGLGLSYFVSL 375

Query: 227 GGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALF 286
           G          I++   +E    D +++++    +      +   +    +  KP +A+ 
Sbjct: 376 GN------SADITSNDLIEFWEEDGRTKLIMLYQESIPNPRKFARLAKRISKKKPILAIA 429

Query: 287 LGYTPAVARDENVWFASSLDEAARL-ACLLSRVTARRNAIAP--------------VSSG 331
            G TPA A+       + +  +      L  +    R +                     
Sbjct: 430 SGVTPAGAKAVASHTGAIVSSSGIAIDALFKQTGIIRASSIDELFSISEFLLHQPLPKGN 489

Query: 332 FICGLYTGGTLAA------EAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTV 385
            +C +  GG L A         GL    L     ++ ++ +   A     +D+       
Sbjct: 490 RVCIVTNGGGLGAITSDWCHQVGLEIAELSERTQESLRNLLPEIASVKNPVDMTASA--- 546

Query: 386 GRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDN 445
                  D  +  Q +  +     V  ++   V                   A  A    
Sbjct: 547 -------DVRMYGQTLKTVAEDENVDAIICIFVAAVSEEKSEEVEKA-VISAAKYANSVG 598

Query: 446 QPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTP 505
           +P+  I   + ++             ++  + V      A  +   ++       +   P
Sbjct: 599 KPVVYIYISSDSKDGVIG--------DEVKVPVYVFPNTAAKVLGKVVEYAKWREKSVEP 650

Query: 506 SL 507
             
Sbjct: 651 VP 652


>UniRef50_C6C0V7 CoA-binding domain protein n=2 Tax=Desulfovibrio RepID=C6C0V7_DESAD
          Length = 702

 Score =  235 bits (600), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 63/467 (13%), Positives = 131/467 (28%), Gaps = 55/467 (11%)

Query: 65  CVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
            + I ++  D                ++   +G    +  +  + S  Q     +LALI 
Sbjct: 18  VIGISADPQDKASIITANLLASGYKGKIFPVNGEGAEVHGLGAFSSVSQLPRGIDLALIC 77

Query: 125 VAGEYAAELANQALDRNLNVMMFSDNV-------TLEDEIQLKTRAREKGLLVMGPDCGT 177
           +  + A +  +   +  +   + +              E +L   A+   ++++GP+C  
Sbjct: 78  LPPDEAIQAIDDLSEILVRAAVVTSGGFGETGREGYRLERELARTAKNHDMIILGPNCMG 137

Query: 178 SMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSRE 234
            M     +  +   +   +GNI  +  SG             G G +  I LG + +  E
Sbjct: 138 LMNTALGMNASLDPDFTLKGNIAFLSQSGAMCSTALDWANSEGVGFSKFISLGNKAVLGE 197

Query: 235 VGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVA 294
                    L  L+ DE ++V+    +   +              KP + L  G TP+ A
Sbjct: 198 AT------MLNYLANDEDTKVIVGYCETLKDGQDFLRTAYDTTFKKPLILLRAGETPSGA 251

Query: 295 RDENVWFASSLDEAARLACLLSRVTARRN---------------AIAPVSSGFICGLYTG 339
           R  +                 ++    +                   P  S       +G
Sbjct: 252 RAASAHAGHLTGATTAYNAAFNQTGVMQAVDIEDMFNLAHAFSCQPLPSGSNVAIITNSG 311

Query: 340 --GTLAAEAAGLLAGHLGVEADDTHQH---GMMLDADSHQIIDLGDDFYTVGRPHPMIDP 394
             G LA + A     ++   +  T +     +   A  +  ID+  D             
Sbjct: 312 GPGILATDMAEKGTLNISRPSSSTLEKMKEVLPRYASLYNPIDMLGDANA---------- 361

Query: 395 TLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATV 454
              ++++  +     V   +L ++       +      +   +             I   
Sbjct: 362 DTYHKVLRAVAED-DVFHSILIILTPAANILEDVEKAAADIIELEKECD----KPIITCF 416

Query: 455 TGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQ 501
            G         +    L  AGI        A     A+        +
Sbjct: 417 MG----DHSTRKARRMLRAAGIPCYEFPEAAVRSLDAMTRCYRWQKK 459


>UniRef50_P76594 Uncharacterized protein yfiQ n=154 Tax=Gammaproteobacteria
           RepID=YFIQ_ECOLI
          Length = 886

 Score =  234 bits (596), Expect = 8e-60,   Method: Composition-based stats.
 Identities = 59/464 (12%), Positives = 135/464 (29%), Gaps = 35/464 (7%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   +     A   +M+ L            + + +A+  V  W          +LA+
Sbjct: 15  IAVIGASMKPNRAGYLMMRNLLAGGFNGPVLPVTPAWKAVLGVLAWPDIASLPFTPDLAV 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG 182
           +         L  +  ++     +       + E  L+  A    + ++GP+    +   
Sbjct: 75  LCTNASRNLALLEELGEKGCKTCIILSAPASQHE-DLRACALRHNMRLLGPNSLGLLAPW 133

Query: 183 TPLAFANVM---PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGIS 239
             L  +        G +  I  S      +         G ++ I LG      +   I 
Sbjct: 134 QGLNASFSPVPIKRGKLAFISQSAAVSNTILDWAQQRKMGFSYFIALG------DSLDID 187

Query: 240 ALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENV 299
               L+ L+ D K+  +    +  ++A R        +  KP + +  G +PA  R    
Sbjct: 188 VDELLDYLARDSKTSAILLYLEQLSDARRFVSAARSASRNKPILVIKSGRSPAAQR---- 243

Query: 300 WFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEA- 358
              ++          + R    R          +  L     L  +   +++      A 
Sbjct: 244 LLNTTAGMDPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGDRLMIISNGAAPAAL 303

Query: 359 ------DDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTL---RNQLIADLGAKPQ 409
                     +   + +    ++ D   +   +  P  + D        + +  L     
Sbjct: 304 ALDALWSRNGKLATLSEETCQKLRDALPEHVAISNPLDLRDDASSEHYIKTLDILLHSQD 363

Query: 410 VRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIA 469
              L+   VI   + A PA        +A      ++ +  +    G         +   
Sbjct: 364 FDALM---VIHSPSAAAPATESAQVLIEAVKHHPRSKYVSLLTNWCGE----HSSQEARR 416

Query: 470 TLEDAGIAVVSSLPEATLLAAALI-HPLSPAAQQHTPSLLENVA 512
              +AG+    +          ++ +  +    + TP+L  N+ 
Sbjct: 417 LFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLRETPALPSNLT 460


>UniRef50_Q2BN19 Acetyltransferase, GNAT family protein n=1 Tax=Neptuniibacter
           caesariensis RepID=Q2BN19_9GAMM
          Length = 914

 Score =  233 bits (595), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 74/506 (14%), Positives = 154/506 (30%), Gaps = 72/506 (14%)

Query: 65  CVAIRSEAADAGIAQAI-MQQLEEALKQLAQGSGSSQA---LTQVRRWDSACQKLPDANL 120
           C+A+   +        + +Q L+E+  + +  + +SQ    +  V  +          +L
Sbjct: 14  CIAVFGASEKENSMGGVVIQNLQESGFKGSLYAVNSQGYEQVHGVSCFKRLSDLPEMPDL 73

Query: 121 ALISVAGEYAAELANQALDRNLNVMMF-SDNVTLED-------EIQLKTRAREKGLLVMG 172
           A+I    E  A++        +   M  +  +++ D         ++K  A+  G+ ++G
Sbjct: 74  AIICSPPESVADIIRGLGASMVKAAMILTGGLSIADGDSSQTLRDEVKEAAKPYGIRILG 133

Query: 173 PDCGTSMIAGTPLAFANVM---PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
           PDC   ++ G  +  +       +G +  +G SG     +         G +H + LG  
Sbjct: 134 PDCMGLLVPGHNMNASYSHVNILKGKVAYVGQSGILGTAMIDWATGQEIGFSHFLTLG-- 191

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSK-PPAEAVRLKIVNAMKATGKPTVALF-- 286
               +   +   + ++ L+ D  +  +          A          +  K  + L   
Sbjct: 192 ----DGADVDMPSVIDYLAQDPYTHAILLQLNRVDGSARDFLSAVRSASRNKLVLVLKND 247

Query: 287 --LGYTPAVARDENVWFASSLDEAARLACLLSRVTARRN---------AIAPVSSGFICG 335
             +G          +     + +AA     + RV               + P+    +  
Sbjct: 248 TFVGEKSGTELAPGIHDDDQVYDAALRRAGVVRVETSDELFNALETLTRMKPMRGERLAI 307

Query: 336 LYTGGT---LAAEAAGLLAGHLGVEA-DDTHQHGMMLDADSH--QIIDLGDDFYTVGRPH 389
           L  G     LA E      G L     D   Q   +L +  +    +DL  D        
Sbjct: 308 LSNGTGPNALATEKLLEQGGQLAKLTEDSIAQLSEILPSHWNRSNPVDLNADA------- 360

Query: 390 PMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLY 449
              DP    + +  L     V  +L+   +       P+        +       N    
Sbjct: 361 ---DPARFAEAVRILTKDKNVDAVLM---LHAPTRLAPSVETADQVIQIARKTPRN---- 410

Query: 450 AIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI----------HPLSPA 499
            +    G         +       AGI+   +  E+      ++              P 
Sbjct: 411 VLTCFMGRA----TAIEARNHCNSAGISTFLTPEESVDAFMHMVDFHRNQDVMRQTPPPY 466

Query: 500 AQQHTPSLLENVAVINIGLRSFALEL 525
            +Q+TP+ ++   +I   L      L
Sbjct: 467 IEQNTPNHVKARELIQTALSEKRDYL 492


>UniRef50_B9Z1Z5 GCN5-related N-acetyltransferase n=1 Tax=Lutiella nitroferrum 2002
           RepID=B9Z1Z5_9NEIS
          Length = 893

 Score =  233 bits (594), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 80/546 (14%), Positives = 158/546 (28%), Gaps = 84/546 (15%)

Query: 57  NNATPNDICVAIRSEAADAGIAQAIMQQ---LEEALKQLAQGSGSSQALTQVRRWDSACQ 113
              +P    VA+   +   G     +           +L   + + + +  +R   S   
Sbjct: 8   PLFSPR--AVAVVGASDTPGSIGQAVFASLLAGNFQGKLFPVNLNHKVVGGMRAVPSVRL 65

Query: 114 KLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNV--TLEDEIQLKT----RAREKG 167
              +  LA+++ A      +      + +  ++ +     + + E ++       AR  G
Sbjct: 66  IEGEVELAVVTTALRALPAILRDCGKKGVKAVLLAKEFADSEQLEREILKESLSIARHFG 125

Query: 168 LLVMGPDCGTSMIAGTPLAFAN---VMPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           + V+GP+    M        +N    +  GN+ ++  S      +       G G +  I
Sbjct: 126 IRVLGPNVLGLMRPVAGFNASNYSSKVRPGNLALVSQSSALCTAMLDWADSKGIGFSSVI 185

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
            +G      E   +     L+ L AD  ++ +        +A R        A  KP V 
Sbjct: 186 SVG------EGLDVDFGEILDYLVADTFTQGILLHVHHIHDARRFISALRAAARTKPVVV 239

Query: 285 LFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARR--------------NAIAPVSS 330
           +  G             ++ ++ A      LSR    R               A   V  
Sbjct: 240 IKSGRYEDDV-TGLTHSSNLVESADVFDAALSRAGVLRVGSISQLFTAAKVLAASFRVQG 298

Query: 331 GFICGLYTG---GTLAAEAAGLLAGHLGVEADDTHQHGMML----DADSHQIIDLGDDFY 383
             +  +  G   G LAA++A L    L   ++ T +          +  + +  +GD   
Sbjct: 299 RRLAIVTNGIGPGVLAADSAYLNGVELAKLSEPTMELLNDALPRNWSHGNPVDIIGD--- 355

Query: 384 TVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARL 443
                     P      +        V  +L+      G      A L+   Q       
Sbjct: 356 --------ASPVRFRTAVKACLDDANVDGVLVIFTPQAGTDHLTTAQLMVGLQ------- 400

Query: 444 DNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI---------- 493
                  + +  G  +     S+       A  A   +   A  +   L           
Sbjct: 401 RESTKPILLSWLGDAK----VSESRELFSKAKCAHFRAPEYAVEVFRNLAAYHHNQRLLL 456

Query: 494 -HPLSPAAQQHTPSLLENVAVIN---------IGLRSFALELQSASKPVVHYQWSPVAGG 543
             P     +Q +P +     +IN         +  R     L + + PV   + +  +  
Sbjct: 457 QTPGPLEGKQVSPDVARARTLINAALAEGRVILSERESKEVLSAFNIPVNPTRLARDSDE 516

Query: 544 NKKLAR 549
             +LA 
Sbjct: 517 AVRLAE 522


>UniRef50_A1RX15 CoA-binding domain protein n=2 Tax=Archaea RepID=A1RX15_THEPD
          Length = 508

 Score =  233 bits (594), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 60/499 (12%), Positives = 137/499 (27%), Gaps = 65/499 (13%)

Query: 51  FWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLEE------ALKQLAQGSGSSQALTQ 104
              +           V + +   +      I + L E          +   +  +  +  
Sbjct: 1   MTSESLKPFFDPRGVVVVGASREEEKPGHVIFRVLLENRKKGLLKAPVYGVNPKADYILG 60

Query: 105 VRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNV-MMFSDNVTL----EDEIQL 159
            + + S      + +LA+I +  E+          + +   ++ S   +     + E ++
Sbjct: 61  EKVFPSVKDIPGEVDLAVIVIPAEHVKRAIEDLGVKGIKAAIIISAGFSEIGRSDLEREV 120

Query: 160 KTRAREKGLLVMGPDCGTSMIAGTPLAF-----------------ANVMPEGNIGVIGAS 202
              A++ G+ ++GP+C       + +                   A    +G + +I  S
Sbjct: 121 AETAKKHGIRIIGPNCIGVYSPWSGVDTIFLPYTKVLEDGREVLNAPRPSKGFVALISQS 180

Query: 203 GTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKP 262
           G         +   G G++H + +G +        +  +  +E L  D+++ V+    + 
Sbjct: 181 GAVGTAALDYMYGEGIGLSHFVSIGNK------ADVDEVELVEYLGGDDRTRVILLYLEN 234

Query: 263 PAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARR 322
                    V       KP V L  G T A  R      A+             R    R
Sbjct: 235 IKRGREFIEVAGKVTLKKPVVVLKAGRTSAGRRAAASHTAALAGVDEVYDAAFRRSGVIR 294

Query: 323 NAIAPVSSGFICGLY-----------------TGGTLAAEAAGLLAGHLGVEADDTHQHG 365
                    +   L                    G +A + A +L   +     +  +  
Sbjct: 295 ANDIEELFDYAKALAMQPPARGERIGIITDGGGAGVMATDIAEMLGLKVPELQGNARREL 354

Query: 366 MMLDADS--HQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGA 423
             L       +   L +     G         +  +    L    +V  +++  +     
Sbjct: 355 EELRERGIFPRYAQLSNPVDLTGSATS----EMFVEATRILLESDEVDAVVVLALHQVPG 410

Query: 424 TADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLP 483
             DP         +  +          +A  TG          +    +  G+    +  
Sbjct: 411 IPDPVK-----LAREISRLAAGYAKPVVAVDTGWSE---AAILERKEFDSMGVPSYPTPE 462

Query: 484 EATLLAAALIHPLSPAAQQ 502
            A    +AL+      + +
Sbjct: 463 RAVKSLSALVRYGKYLSSR 481


>UniRef50_A2BLI1 Universally conserved protein n=1 Tax=Hyperthermus butylicus DSM
           5456 RepID=A2BLI1_HYPBU
          Length = 476

 Score =  232 bits (592), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 72/467 (15%), Positives = 144/467 (30%), Gaps = 60/467 (12%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLALI 123
           VA+   +   G    ++    +   +      + ++  +  ++ + +        +LA++
Sbjct: 21  VAVIGASRKPGKVGYMVLYNLKNSYEGPIYPVNPNADEILGLKAYPTIMDVPDPVDLAVV 80

Query: 124 SVAGEYAAELANQALDRNLNVM-MFSDNV------TLEDEIQLKTRAREKGLLVMGPDCG 176
           +V  +   ++ +QA  R +  + + S          +E E +L    R+ G+ ++GP+C 
Sbjct: 81  TVPAKMVPDVVDQAGRRGVRAVIVISAGFREVGGEGVELEKRLLEVVRKHGIRMLGPNCL 140

Query: 177 TSMIAGTPLAFA-------NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
                 T +           +  +G I  I  SG     L   +     GI+  I +G +
Sbjct: 141 GVYSPSTGINATFLDPEKQGLPGKGPIAFISQSGALGAALLDWLDANQFGISKFISIGNK 200

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAV--RLKIVNAMKATGKPTVALFL 287
                   I     L  L  D +++ +A   +  A     R +         KP V L  
Sbjct: 201 ------ADIDEADLLAYLRKDPETKSIAMYIEGVAPGEGGRFRRALEETTHEKPVVILKS 254

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARR--------------NAIAPVSSGFI 333
           G T A AR  +    S          +  +                       P+    +
Sbjct: 255 GRTAAGARAASSHTGSLAGSYQLYETIFKQTGVIPAYDTAQLFEMALALALQPPMLGDRV 314

Query: 334 CGLYTGGTLAAEAAGLLAG------HLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGR 387
             +  GG     A+  LA        L  E     +  ++  A     +D+         
Sbjct: 315 AIITMGGGSGVMASDNLAEKGLKVVELSPETQAKLRKVLLPIASPRNPVDVTGSATD--- 371

Query: 388 PHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQP 447
                      + I  +    +V  +    +I +   A     L                
Sbjct: 372 -------EHFLESIRIVVESGEVDGI---FLIPYLNLASITPELPRKIAALVKEIQQKYR 421

Query: 448 LYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH 494
           +  +A+VT  ++     +      ++AGI V S+   A     AL  
Sbjct: 422 IPFVASVTAGKKT---WALAKIMEKEAGIPVYSNEASAARAMWALRQ 465


>UniRef50_Q5P5S5 Predicted Acetyl-CoA synthetase n=2 Tax=Proteobacteria
           RepID=Q5P5S5_AZOSE
          Length = 727

 Score =  232 bits (592), Expect = 3e-59,   Method: Composition-based stats.
 Identities = 84/520 (16%), Positives = 148/520 (28%), Gaps = 64/520 (12%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSS--QALTQVRRWDSACQKLPDANLAL 122
           +AI   + D        M  L +     A    +     +  VR + +        +LAL
Sbjct: 22  IAIIGASTDPTKRGYKAMVGLIKDGYPGAIYPINPKVDNVLGVRTYATLDDIPGPVDLAL 81

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDC 175
           I         L      + +            +       E Q+   ARE G+ ++GP+ 
Sbjct: 82  ICTPAATVPGLVADCGRKGVKGAAILASGFRETGPAGARLEQQVLAAAREGGVRLIGPNT 141

Query: 176 GTSMIAG--TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAG-EGITHAIGLGGRDLS 232
                      L     +  GNIG I  SG  +  L  +    G  G +  +G G +   
Sbjct: 142 SGMFNLHKKVNLLALANVKPGNIGFISQSGNMLLSLVLEAEHNGHVGFSTYVGPGNQT-- 199

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                I     L  L  D  + V  F  +   +  R           KP V    G T  
Sbjct: 200 ----DIGFNDYLRYLGEDPDTRVATFYVEGFRDGQRFLHNAREITAVKPVVVYKSGATEQ 255

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRNA--------------IAPVSSGFICGLYT 338
             +  +    +     A    LL +V                    +       +  +  
Sbjct: 256 GKKAASSHTGALAGSYAMTVDLLRQVGVSVVQHSNEILPVAEGLGLLQHAPGKRVAVVSD 315

Query: 339 GG---TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPT 395
           GG   T+A++        L    + T +    +       ++  D   +        +P 
Sbjct: 316 GGGQATIASDRIIEAGLELAELGEATKKRLGAILLPQASPVNPVDVAGS-----SDANPA 370

Query: 396 LRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAW---QKACAARLDNQPLYAIA 452
           L    +A +     V  + L  + G G     A  L+       ++            + 
Sbjct: 371 LLADCLAIVADDDNVDAVFLVGMFG-GYHIRFAEDLLGGEMRGAESMIELARRIDKPVVV 429

Query: 453 TVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAAL----IHPLSPAAQQHTPSLL 508
                   P         L +AG+ V +S+  A  + AAL    ++    A Q   P+++
Sbjct: 430 YSLYAPVKPPAL----RRLHEAGLPVYTSIEYAVRVLAALGERGVYLQDAANQAPLPAMM 485

Query: 509 ENVAVI-----------NIGLRSFALELQSASKPVVHYQW 537
            N A +           N+        L++    V     
Sbjct: 486 PNDATLAIFAAAQAEARNLFEFEAKTLLRAHGVDVPAEAL 525


>UniRef50_B6JHC2 N-acetyltransferase n=5 Tax=Rhizobiales RepID=B6JHC2_OLICO
          Length = 898

 Score =  231 bits (589), Expect = 5e-59,   Method: Composition-based stats.
 Identities = 70/477 (14%), Positives = 144/477 (30%), Gaps = 49/477 (10%)

Query: 66  VAIRSEAADAGIAQAI-MQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +   G    I +  +     +      +     L   R +          +L +
Sbjct: 15  VAVIGASLRHGSVGHIVLNNIVNGGFEGEIWPVNPKYTDLNGRRCYPCVSDLPGIPDLGV 74

Query: 123 ISVAGEYAAELANQALDRNLNV-MMFSDNVTLEDEIQ--LKTRAREKGLLVMGPDCGTSM 179
           I        +L  +  ++     ++ +  +T E+ ++  +   ++   L ++GP+    +
Sbjct: 75  IITPAAVVPDLIKELGEKGTRAAVVITAGITRENGLRQAILDASKPHLLRIIGPNTLGLV 134

Query: 180 IAGTPLAFANVM---PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVG 236
           +    L  +        GNI ++  SG     L    A  G G +  + LG      ++ 
Sbjct: 135 LPLAKLNASFAHMGAAPGNIALLSQSGAIATSLIDWAAANGIGFSQIVSLG------DMA 188

Query: 237 GISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARD 296
            +     L ML+ D ++  +    +      +        A  KP +A+  G     A+ 
Sbjct: 189 DVDVADCLNMLAGDAQTRAIVMYLESVPNPRKFMTAARAAARVKPVIAIKPGRHAEAAKA 248

Query: 297 ENVWFASSLDEAARLACLLSRVTARR--------------NAIAPVSSGFICGLYTGGTL 342
                 +       +   L R    R                 +P+    +  +  GG  
Sbjct: 249 AATHTGALSGVDRVVDAALRRAGILRVNELADLFGATETIARFSPIERARVGIVTNGGGA 308

Query: 343 AAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID---PTLRNQ 399
              A   L    G  A  + +    LD             ++   P  ++    P     
Sbjct: 309 GVLAVDRLMDFHGELAVLSPKTIAALDQT-------LPSNWSHANPVDIVGDAPPERYRA 361

Query: 400 LIADLGAKPQVRVL-LLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTE 458
            +  + A P V VL +++   G  +++D AA+ V++  K             +    G  
Sbjct: 362 AVEAVAADPDVDVLMVMNCPTGVASSSD-AATTVASLAKNGTIND----KPVLTCWLGE- 415

Query: 459 RDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVIN 515
              Q        L+ AGI    +        + L          H      +  V +
Sbjct: 416 ---QSARGARRLLQAAGITSYETPAATATAVSYLTDWSRSQKMLHRVPSDRSTDVTS 469


>UniRef50_A1RXS7 CoA-binding domain protein n=5 Tax=Archaea RepID=A1RXS7_THEPD
          Length = 704

 Score =  231 bits (589), Expect = 5e-59,   Method: Composition-based stats.
 Identities = 68/530 (12%), Positives = 148/530 (27%), Gaps = 61/530 (11%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQL---AQGSGSSQALTQVRRWDSACQKLPDANLA 121
           VA+   + +       +++ L EA          + ++  +  ++ + S  +     +L 
Sbjct: 15  VAVVGASRNPEKIGYQVVKNLLEAGFPRERIFPVNPNADEILGLKCYKSVSEIPYQVDLV 74

Query: 122 LISVAGEYAAELANQALDRNLNVM-MFSDNVT----LEDEIQLKTRAREKGLLVMGPDCG 176
           +++V       +   A  + +  + + +        ++ E ++ + A+  G+ ++GP+  
Sbjct: 75  VVAVPAPAVPGVLEDAGRKGVKAVAVITSGFKEIGNVDLEQRIASIAKNYGMRLLGPNIV 134

Query: 177 TSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
                   +  +    +   G I  I  SG     L     L G G++  + +G +    
Sbjct: 135 GICDTVKRVNASFCQGLPKPGEIAFITQSGALGIALVGWTKLKGIGLSDLVSIGNK---- 190

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAV 293
               +     +E    D+ ++V+    +  ++  R        A  KP + L  G     
Sbjct: 191 --ADVDETDLVEFFGEDQYTKVITAYLEGVSDGRRFLEAARRVARRKPIIVLKAGRGVRT 248

Query: 294 ARDENVWFASSLDEAARLACLLSRVTARRNAIAP--------------VSSGFICGLYTG 339
                    S     A       +                             +  L  G
Sbjct: 249 IGAIKSHTGSLAGSFAAYEAAFKQSGILLARSFVELFDWATAFAKTHIPRGENVVVLTNG 308

Query: 340 GTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQ 399
           G     A   L  +     D        L         + +     G    M D      
Sbjct: 309 GGAGIMATDALEDYGIRLMDIPQDLAEKLRKHMPPFGSVFNPVDLTG----MADAEQYYG 364

Query: 400 LIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTER 459
            + DL     V  +L  V+    A  +P     +  +              +A+  G E 
Sbjct: 365 ALKDLLMHDSVDAVL--VLYCHTAITNPQEIAEALLRAVRETESK---KTVLASFIGGEE 419

Query: 460 DPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSL-------LENVA 512
                ++    L + GI    S  +A     A+        +    +             
Sbjct: 420 ----VNEACGKLTENGIPCYESPEKAASSLGAIYRYKHMLEKLDRRTEVAVSVDVEAARH 475

Query: 513 VINIGL---------RSFALELQSASKPVVHYQWSPVAGGNKKLARLLER 553
           V+   L            A  +     PV+  + +       ++AR +  
Sbjct: 476 VVRSALKEGRTTLTPSEAAALVGYYGIPVLAKKIAKSPEEAVRIAREIGY 525


>UniRef50_A8BPG2 Acetyl-CoA synthetase n=4 Tax=Hexamitidae RepID=A8BPG2_GIALA
          Length = 726

 Score =  230 bits (587), Expect = 9e-59,   Method: Composition-based stats.
 Identities = 58/497 (11%), Positives = 143/497 (28%), Gaps = 57/497 (11%)

Query: 61  PNDICVAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQ--ALTQVRRWDSACQKLPD 117
            N   VA+   + +AG     ++  ++E+         +     +   + + S       
Sbjct: 19  TNPASVAVIGASPNAGKVGNTVVTNIKESGYTGKVYPINPTATEILGYKTYKSVLDVPDS 78

Query: 118 ANLALISVAGEYAAELANQALDRNLN-VMMFSDNV------TLEDEIQLKTRAREKGLLV 170
            ++ ++ +  +     A +   + +  +++ +          ++ E  L    ++ G+ +
Sbjct: 79  IDVVIVVIPSKAVLAAAKECAQKKVKSLVVITAGFKEIGGEGVQMEQDLTKICKDAGIRL 138

Query: 171 MGPDCGTSMIAGTPLAFANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
           +GP+C   +       FA+  P +G+I  +  SG  +  +       G G ++ I LG +
Sbjct: 139 VGPNCLGIVTPNLNCTFASAKPSKGSIAFLSQSGAMLTSILDWALTNGIGFSNFISLGNK 198

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
                   +  +  +  ++ D  ++++    +   +  +           KP + L  G 
Sbjct: 199 ------ADVDEVDLIMEVAEDPNTDIILLYLESIVDGRKFLEQIPTCVHKKPVIILKSGT 252

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARRNAI---------------APVSSGFIC 334
           + A A   +    +             +    R A                 P    F+ 
Sbjct: 253 SAAGAAAASSHTGALAGNDIAFDLAFEKAGVLRAATMSDLFDLGRLFVSHRLPKGDNFVI 312

Query: 335 GLYTGG-----TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPH 389
               GG     T A E   +    L  +  +     +  +A     +D+  D        
Sbjct: 313 VTNAGGPGIVTTDAFETYHVGMAALSDKTKEALAKVLPGEASVKNPVDIVGDA------- 365

Query: 390 PMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLY 449
               P      +     +P   V    +++       P        +             
Sbjct: 366 ---PPKRYEDALEICFKEPPETVAGAVILVTPQGQTKPCEVA----ELCTRMYAKYPDRL 418

Query: 450 AIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLE 509
            ++   G         +    L +A + V      A     A++       +       +
Sbjct: 419 VVSAFMGG----LTMQEPSKILNNAKMPVFPFPEPAIHATGAVLKY--RKIKNRKTLAEK 472

Query: 510 NVAVINIGLRSFALELQ 526
            V V  +        + 
Sbjct: 473 KVEVFKVDNERIKKIIA 489


>UniRef50_C7LRJ9 CoA-binding domain protein n=1 Tax=Desulfomicrobium baculatum DSM
           4028 RepID=C7LRJ9_DESBD
          Length = 697

 Score =  230 bits (585), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 80/476 (16%), Positives = 149/476 (31%), Gaps = 65/476 (13%)

Query: 65  CVAIRSEAADAGI-AQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALI 123
            +A+      AG  A+ ++  LE    Q    S +  +    R    A   L   +LA++
Sbjct: 14  AIAVVGSFDSAGALARVVLSNLEGWGYQGRIVSVNWTSQKDPR----ALDDLKGVDLAVV 69

Query: 124 SVAGEYAAELANQALDRNLNVMMFS-------DNVTLEDEIQLKTRAREKGLLVMGPDCG 176
            +A E+  E   Q  D  +  ++ +              E  +   A  + L ++GP+C 
Sbjct: 70  CLAPEFVLEALEQVADMGVKAVIITSAGFREIGGQGYYLEESIIQLAERRNLTLLGPNCL 129

Query: 177 TSMIAGTPLAFANVMP---EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
                   L  + +     +GNI     SG+    +    A    G +    LG R +  
Sbjct: 130 GVASWADHLNASLIARLPSQGNIAFFSPSGSMCNAILDWAASEEIGFSKFASLGNRAVID 189

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAV 293
           E         L+ L+ D ++ V+    +      R   ++      KP + L  G T   
Sbjct: 190 EAS------MLQFLAEDPQTSVIIGYLEGMNNGRRFARISQTITHEKPVIMLQAGMTEHG 243

Query: 294 ARDENVWFASSLDEAARLACLLSRVTARRN---------------AIAPVSSGFICGLYT 338
            +  +    +           L +    +                   P          +
Sbjct: 244 QKAISSHVGALTGSERAYQTALKQAGIIQVDNLSSLFDLARMFGTQPLPKGPNLAIVTNS 303

Query: 339 G--GTLAAEAAG---LLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID 393
           G  G LAA+      L+   LG +        +   A +  ++D+G D            
Sbjct: 304 GGAGILAADGMAGTSLILPRLGRDTAARLVDILPRHAQTSNLVDIGMDAT---------- 353

Query: 394 PTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIAT 453
           P    Q +  +    Q+++ LL +  G G         + A  +   A            
Sbjct: 354 PVQYAQALDTVLKDRQIQMALLVIAPGLGVD-------LPAIVRELVALPRAVGKAVAVC 406

Query: 454 VTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLE 509
           + G E       ++   L+  G+    S P+A L +   +  L  A  +     +E
Sbjct: 407 LIGQE----GVMEEKRFLQRHGLPCY-SNPKAALASFEAM--LRYAGWKTKSYPVE 455


>UniRef50_C4ZP63 CoA-binding domain protein n=1 Tax=Thauera sp. MZ1T
           RepID=C4ZP63_THASP
          Length = 886

 Score =  230 bits (585), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 74/455 (16%), Positives = 123/455 (27%), Gaps = 54/455 (11%)

Query: 66  VAIRSEAADAGIAQA-IMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   +   G     I + L E   +      +    ++       S        +LA+
Sbjct: 16  IAVIGASDAPGSVGRVIFRNLVEGGYRGTLYAVNPKYGSIQDHPCHRSVEDIGRPVDLAI 75

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG 182
           I+        +  Q     +   +         E ++   ARE  L ++GP        G
Sbjct: 76  IATPARMLHSVTAQCGRSGVRNAVIISASGNALERRIVETARETRLRLIGPGSLGIARPG 135

Query: 183 TPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGIS 239
           + +  A     +  G I +I  SG     +         G +  I LGG         I 
Sbjct: 136 SGINAALTRIAVKPGEIALISQSGAMCSVVLDWALTNDVGFSSVISLGG------TVDID 189

Query: 240 ALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENV 299
               LE L  D ++  +         A +        A  KP + L  G       +   
Sbjct: 190 YGETLEYLIHDTQTRYILLHVDHIRNARQFMSALRSAARVKPIILLKAGRHGRSDNNAAD 249

Query: 300 WFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAG------- 352
              + L +       + R    R             L  G     ++  +++        
Sbjct: 250 ADNAGLAD-VVFDAAMRRAGVVRVQNIDQLFFAAKALSCGFRPREDSLAIVSNGSGPADL 308

Query: 353 -------------HLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQ 399
                         LG     T +     +  SH  +DLG D              L   
Sbjct: 309 AADRAKDLGTGLVGLGSPTVATLERLGGRERHSHNPLDLGGDASAQ----------LYRD 358

Query: 400 LIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTER 459
            I  L     V  +L  V++   A  DP          A   RL            G  +
Sbjct: 359 AILALSEDAAVSNVL--VILSPHALVDPVEVAQDIIDLAAQVRLQ-----LCCCWMGGGQ 411

Query: 460 DPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH 494
             + R+         G+ V SS   A  L   +  
Sbjct: 412 VAEARALLARA----GLPVFSSPEAAIELFHNISR 442


>UniRef50_Q0S1K2 Possible acetyl-CoA synthetase n=10 Tax=Actinomycetales
           RepID=Q0S1K2_RHOSR
          Length = 920

 Score =  229 bits (584), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 79/459 (17%), Positives = 142/459 (30%), Gaps = 49/459 (10%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGS--SQALTQVRRWDSACQKLPDANLAL 122
           VA+   + D      A++  L  A         +   +++  VR + S      + +LA+
Sbjct: 244 VAVIGASTDRAKVGNAVLTNLLRAGFTGPVYPVNAEHRSVHGVRAYPSVRDIPDEVDLAV 303

Query: 123 ISVAGEYAAELANQALDRNLNV-MMFSDNVTL------EDEIQLKTRAREKGLLVMGPDC 175
           ++V  E    + +  L + +   ++ S   +       + E +L   AR  G+ ++GP+ 
Sbjct: 304 VAVPAESINAVLDDCLVKGVKALVVVSSGFSETGMDGRQSERRLVHAARAHGMRLIGPNA 363

Query: 176 GTSMIA----GTPLAFANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
                           A V+P  GN+G    SG     +  + A +  G++  +  G R 
Sbjct: 364 LGVANNDSEVSLNATLAPVLPSPGNVGFFCQSGALGIAILDEAARSRIGLSAFVSAGNR- 422

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
                  +S    L+   +D  +EV+    +      +   +    A  KP VA+  G  
Sbjct: 423 -----ADVSGNDLLQYWDSDPATEVVLLYLESFGNPRKFSRIARRVARNKPIVAVKSGRH 477

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLL 350
                         +D++   A               V  G I  L+    L        
Sbjct: 478 AVPPALAAS--GGEMDDSIVRA--------LFEQAGVVQVGSISQLFDCALLFGYQPLPA 527

Query: 351 AGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQV 410
              L V  + T    +  DA   + + +GD         P   P      +        V
Sbjct: 528 GPRLAVVGNSTALGVLAADAARSEGLQVGDPVD----LGPQAGPEEFAAAVRTALTSFDV 583

Query: 411 RVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIAT 470
             ++   V        P      A ++A            + T    E  P   +     
Sbjct: 584 DSVIAVFVPPVAI---PVEPYAQALREAVREAD----KPVLTTFLAAEGVPDVLA----V 632

Query: 471 LEDAGIAV---VSSLPEATLLAAALIHPLSPAAQQHTPS 506
             + G      V S P     A AL      +A +  PS
Sbjct: 633 RGEDGHPTRGSVPSYPGPERAALALARAWRYSAWKSKPS 671


>UniRef50_B1T453 CoA-binding domain protein n=1 Tax=Burkholderia ambifaria MEX-5
           RepID=B1T453_9BURK
          Length = 730

 Score =  229 bits (584), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 87/525 (16%), Positives = 153/525 (29%), Gaps = 55/525 (10%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   + D        +Q+L E          +     +  +  + S      D +LAL
Sbjct: 15  IAVVGASKDTTKRGFRSIQKLLEDGFAGTIYPVNPKEDEILGLPCFKSVEDIPGDFDLAL 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDC 175
           +    +    +  Q   +N    +        +       +  +   AR  G+ ++GP+ 
Sbjct: 75  VCTPAKTLPGVIEQCGRKNAKGAVVLAGGFAEAGAEGAALQQAMVQAARRHGVRIIGPNT 134

Query: 176 GTSMIAGTPLAFANV--MPEGNIGVIGASGTGIQELCSQIALAG-EGITHAIGLGGRDLS 232
                            + +G IG++  SG     L ++    G  G++  +G+G     
Sbjct: 135 SGIFNTHNQCNVVGFSQLRKGAIGLLSQSGNMALSLVTEAQANGEVGLSTYVGIGNE--- 191

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                I     L+  + DE + V+    +   +              KP V    G T A
Sbjct: 192 ---SDIRFDEYLDYFADDENTSVVIAYVEGMKDGPAFLKALRDITRKKPVVLYKSGRTGA 248

Query: 293 VARDENVWFASSLDEAARLACLLSRVTAR--------------RNAIAPVSSGFICGLYT 338
                     +   + A    +L +  A                + + P+ S  I  L  
Sbjct: 249 GISSAKSHTGALAGDYAVSQGVLRQAGAVLATKSDEILSLAEALSLLPPLKSRRIAVLAD 308

Query: 339 GG---TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPT 395
           GG   T+AA+A       LG  +  T +    +   S  I +  D            +P 
Sbjct: 309 GGGHATIAADALTERGLELGTLSPPTQRRLSAILPPSAAIANPIDVAGGT-----DANPA 363

Query: 396 LRNQLIADLGAKPQVRVLLLDVVIG-----FGATADPAASLVSAWQKACAARLDNQPLYA 450
           L  +    L     V  LL+  + G     F  +  P     SA   A +AR        
Sbjct: 364 LFAECARILLEDDHVDGLLITGLYGGYGVRFSQSLTPVEMATSAEIAAMSARF---GKPI 420

Query: 451 IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQ------HT 504
           +            R   +  + +AGI V  SL  A     A+        +         
Sbjct: 421 VIHSLYASLYSDLRPAPLTCVREAGIPVYDSLEMAVRCIEAVAQFGEAQRRPCPDFGQTM 480

Query: 505 PSLLENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLAR 549
           P       VI        + +          +    A     LAR
Sbjct: 481 PRSPGFARVIARCREEMRVVVLEHEARQALVEAGVPASAPAILAR 525


>UniRef50_C0QHK1 SucC2 n=1 Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QHK1_DESAH
          Length = 709

 Score =  229 bits (583), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 79/481 (16%), Positives = 147/481 (30%), Gaps = 55/481 (11%)

Query: 62  NDICVAIRSEAADAGIAQ-AIMQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDA 118
           N   VAI   + +        ++ L E   +      +    ++  +  +DS      + 
Sbjct: 7   NARSVAIIGASKNPTKRGYQAIKTLLEDGYEGKIFPVNPREDSVLGIPCYDSITSIDQEV 66

Query: 119 NLALISVAGEYAAELANQALDRNLNVMMFSDNV-------TLEDEIQLKTRAREKGLLVM 171
           +LALI+   +    L  +  ++ +   +                E  +   A+E G+ ++
Sbjct: 67  DLALITTPAKTIPALLKECGEKKVAGAVIVAGGFRELGTEGKALEALVVETAKESGVRII 126

Query: 172 GPDCGTSMIAGTPLAFANV--MPEGNIGVIGASGTGIQELCSQIA-LAGEGITHAIGLGG 228
           GP+    +   + +    +   P G I +I  SG     L ++      EG T+ IG+G 
Sbjct: 127 GPNTSGMINMKSNMNLVGIKNAPRGGIALICQSGNMALTLITEAMIRKHEGFTYYIGVGN 186

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG 288
                    I     LE L  D +++ +    +  ++  +           KP V L  G
Sbjct: 187 E------ADIKFHEYLEFLRNDPETKSILMYVEGMSQGRKFLQQAYETTKKKPIVLLKSG 240

Query: 289 YTPAVARDENVWFASSLD--EAARLACLLSRVTARR--NAIAPVSSGF----------IC 334
            +    R       S     E A  A   + +T     + + PV+             + 
Sbjct: 241 RSATGKRSAGSHTGSLAGMSEVANAAYGRAGITVIENSDELFPVAQTLSSQPSIKNNQVA 300

Query: 335 GLYTGGTLAAEAAGLLAG------HLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRP 388
            L  GG  A   A LL+        L        +  +   A     +D+     +    
Sbjct: 301 ILADGGGHATIGADLLSDYGIGLPELSETTRAKLRAILPAAASVVNPVDVAGGTDS---- 356

Query: 389 HPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKAC---AARLDN 445
               +P +       +   P V  LL+  + G G     A SL    + A       +  
Sbjct: 357 ----NPAIFADCANIILKDPNVGGLLIVGLFG-GYGIRFAESLAIPEEDAAHRIGKMVKQ 411

Query: 446 QPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTP 505
           +    +     +  +          L    I V  SL       A+L          H  
Sbjct: 412 KNKPIVVHSLYSSYNSHPIE----LLRYYNIPVHDSLDITCKCIASLCQYGDYLKSYHAK 467

Query: 506 S 506
           +
Sbjct: 468 T 468


>UniRef50_C7DI26 CoA-binding domain protein n=1 Tax=Candidatus Micrarchaeum
           acidiphilum ARMAN-2 RepID=C7DI26_9EURY
          Length = 479

 Score =  228 bits (582), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 63/458 (13%), Positives = 132/458 (28%), Gaps = 43/458 (9%)

Query: 62  NDICVAIRSEAADAGIA-QAIMQQLEEALKQLAQGSGSSQA---LTQVRRWDSACQKLPD 117
           N   VAI   + +       I+Q   +          ++ A   +  +  + +  +    
Sbjct: 28  NPKSVAIVGASQNPDKVGHVILQNYLDVGYSGKLYPVNANASGKILGLESYRNITEIKKP 87

Query: 118 ANLALISVAGEYAAELANQALDRNLNVMMF-----SDNVTLEDEIQLKTRAREKGLLVMG 172
            +LA+I++  ++ +EL  +     +  ++      ++   ++ E +L   A +  + ++G
Sbjct: 88  IDLAVIAIPAKFTSELITECHKAGVKSIVVVSSGYAEIGEVKLEQELIDLANKYKIPLLG 147

Query: 173 PDCGTSM-----IAGTPLAFANVMPE--GNIGVIGASGTGIQELCSQIALAGEGITHAIG 225
           P+C   M     +    L    +     G +  +  SG         IA  G G++  I 
Sbjct: 148 PNCLGVMDLKSRVDTLFLPTFKIDRPSIGGVSFVSQSGAVGSSTLDIIANEGFGLSKFIS 207

Query: 226 LGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVAL 285
            G   +      I     L  L+ DE ++V+ +  +                  KP V L
Sbjct: 208 YGNASV------IDETDILNYLAKDEDTKVILYYIEGVKRGRAFIEAAKKATLKKPIVVL 261

Query: 286 FLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAE 345
             G T A ++  +   AS          +  +    R         F     +       
Sbjct: 262 KGGRTEAGSKAAHSHTASLAGSYEAYDAVFRQFGLIRADDIQDFVSFSKIFVSQPKCTGN 321

Query: 346 AAGLLAGHL-------GVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPM---IDPT 395
              ++                +  Q   + +     +         V  P  M    D  
Sbjct: 322 RVAIMTNGGGVGVVGTDSLYSNGLQLAELSEESKKALKKALPPIVGVNMPIDMAGDADDK 381

Query: 396 LRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVT 455
             +  +  +     +  ++   +              S                 +    
Sbjct: 382 RFSATLDIISKDQNIDAIMAITLFQ-------TPGADSRVASTLIHYGTTMEKPMVVVSI 434

Query: 456 GTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
           G       +      +E +GI V  S   A+   AALI
Sbjct: 435 GGSYTGVHKM----MMERSGIPVYDSPNTASRALAALI 468


>UniRef50_B8FCT2 CoA-binding domain protein n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FCT2_DESAA
          Length = 464

 Score =  228 bits (581), Expect = 4e-58,   Method: Composition-based stats.
 Identities = 67/469 (14%), Positives = 144/469 (30%), Gaps = 61/469 (13%)

Query: 66  VAIRSEAA--DAGIAQAI-MQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   +   D G        Q  E    L   + +   ++ V+ + S        +L +
Sbjct: 12  IAVVGASPGFDGGKMPFFQFLQFMEYKGALYPVNPAHAEISGVKAYPSLDDVPETVDLVI 71

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-----SDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
             +   +A +    A       + F     S+   +E E +L   AR   + ++GP+C  
Sbjct: 72  AQIPARFAIDTVKAAGRNGAPFVHFFTSGFSEVGNMELEKELVETARASNVRLVGPNCIG 131

Query: 178 SMIAGTPLAFANVMPE---GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSRE 234
            + A + + F         GN+G +G SG                +  A+  G +     
Sbjct: 132 VLCAESRITFNMEFKPNGKGNVGFLGQSGGVSDNFVRMSGSRKIRLNKAVSYGNQ----- 186

Query: 235 VGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVA 294
              +     L   + D + E  A   +                  KP + L  G T   A
Sbjct: 187 -ADLKLEDFLAYFAEDPEIEAAAIYVEDVKNGPAFLDALGKTTASKPVILLKGGSTQRGA 245

Query: 295 RDENVWFASSLDEAARLACLLSRVTAR---------RNAIAPVSSGFICG-----LYTGG 340
           +       +   +    +  +++                +   S+    G     L  GG
Sbjct: 246 KAAASHTGAMAGDFKIFSSAVNQKGGIIVDTFEQMMDLMMLATSTRLPRGNRVGFLGAGG 305

Query: 341 -------TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID 393
                   LAA+A   +        D   +    ++  +   +DLG   +         D
Sbjct: 306 GTSVCFTDLAAKAGLEMPVLAQAVQDRISEKIPNVNTSTANPVDLGAFGF---------D 356

Query: 394 PTLRNQLIADLGAKPQVRVLL----LDVVIGFGATADPAASLVSAWQKACAARLDNQPLY 449
            ++    +  +     + V++    LD +  F       AS          A++    + 
Sbjct: 357 FSIMAHTMLAMDQDENIDVIMPYFSLDFITSFAPH---MASSGPEIILETVAKMKKPVIP 413

Query: 450 AIATVTGTERDPQCRSQQI----ATLEDAGIAVVSSLPEATLLAAALIH 494
            ++       D     +      +   + G+AV +++ +    A++++ 
Sbjct: 414 ILSKF---AEDVLEMEKVRIEMFSVFREGGLAVFNTIQDCVNAASSILK 459


>UniRef50_C0D886 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0D886_9CLOT
          Length = 695

 Score =  227 bits (579), Expect = 7e-58,   Method: Composition-based stats.
 Identities = 70/509 (13%), Positives = 146/509 (28%), Gaps = 59/509 (11%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLALI 123
           + +   +  +G      + + E +++      +     +     + +  +     +LA+I
Sbjct: 12  ICVIGASEKSGFGGDTCRNVIEYMREGSYYFVNPGRDEVFGKPCYRTVEEVPGSFDLAVI 71

Query: 124 SVAGEYAAELANQALDRNLNV-MMFSDNV-------TLEDEIQLKTRAREKGLLVMGPDC 175
                   EL   +  +     ++F+            E++ +L    +E  + +MGP+C
Sbjct: 72  CTPQGTVEELLKSSRAKGAGAAVVFASGYKEIGSAQGRENQERLTRLCKELDMALMGPNC 131

Query: 176 GTSMIAGTPLAFANVM-----PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
              +     +     +      +G +GV+  SG     L       G   ++ I  G   
Sbjct: 132 AGFVNYTDDVYPFAFLSESRDRKGTVGVVSQSGQICLSLMD---SPGMKFSYVISSGNSA 188

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK-IVNAMKATGKPTVALFLGY 289
           +      +     LE L  DE ++V+A   +      +    +       KP V L  G 
Sbjct: 189 V------VRMEDYLEFLVEDESTKVVAMYLEGVQNVPQFLDCLKRAAMKRKPVVILKAGR 242

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARRNA----------------IAPVSSGFI 333
           +    R       S     A    +  +    R                    P   G  
Sbjct: 243 SEKGGRLAASHTGSLSGADAVFDAVFRKYGVIRVDDVEELMAVSMMFSILPGLPKRPGIA 302

Query: 334 CGLYTGG--TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPM 391
               +GG   + A+              +T +             +  D   T+      
Sbjct: 303 SMNLSGGETGVCADVGQTWGIEYPDFQAETLERLREQLPSYASPANPLDMTATL-----S 357

Query: 392 IDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAI 451
            D       +  + + P V ++ +   +     ADPA   ++   +  AA    +P+  I
Sbjct: 358 YDVQAYAGALRTVMSDPNVGLVAIGYTL-LERIADPAICYMTEAIELVAAEPGAKPMVMI 416

Query: 452 ATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQH-----TPS 506
             +  T        +    LE AG+ V+     A  +   L    +   ++       P+
Sbjct: 417 PFLENTRN-----EEYARRLECAGVPVLPPTVYAFKILRYLEEFAAYRPEERCLDMTAPA 471

Query: 507 LLENVAVINIGLRSFALELQSASKPVVHY 535
             E      +        L          
Sbjct: 472 PREKNEKTALSEHESKEFLCGHGIETPRE 500


>UniRef50_C7QE97 FdrA family protein n=1 Tax=Catenulispora acidiphila DSM 44928
           RepID=C7QE97_CATAD
          Length = 629

 Score =  227 bits (579), Expect = 7e-58,   Method: Composition-based stats.
 Identities = 124/384 (32%), Positives = 186/384 (48%), Gaps = 23/384 (5%)

Query: 3   HAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPN 62
           H  +++G + DSV+LM+  R ++    V  V V M T  N ALL   G+      +A P 
Sbjct: 20  HVEVRRGEYHDSVTLMLAGRAVAGVAGVGRVLVAMATELNVALLAELGYA--ALPDAGPG 77

Query: 63  DICVAIR--SEAADAGIAQAI-------MQQLEEALKQLAQGSGSSQALTQVRRWDSACQ 113
           D+ VA     +  DA  + +        +  L ++L     GS ++       R D    
Sbjct: 78  DLVVAFTCEGDGGDAEGSDSADATESAALAALADSLTPQPGGSITAPGHPHQGRPDQPAP 137

Query: 114 KLP-------DANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREK 166
           +          A + LIS  G  +   A ++L+   + ++FSDN+ +  E++LK  AR +
Sbjct: 138 RTTATALGRTSAPITLISTPGLASVAEAMESLEYGASPIIFSDNIPIHHEVRLKEEARRR 197

Query: 167 GLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGL 226
           GLLVMGPDCGT ++ GT LAFA ++  G I ++ ASGTG Q+L + +  AG GI H +G+
Sbjct: 198 GLLVMGPDCGTVVLHGTGLAFATIVRPGPISLVAASGTGAQQLMALLDAAGTGIHHCLGV 257

Query: 227 GGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALF 286
           GGRDL+ +V G S L AL  L+ D  +E++  VSKPP   +  KI       GKP    F
Sbjct: 258 GGRDLTEQVAGRSTLAALTALADDPATELITVVSKPPHPTIAAKIQAHAATLGKPVHFAF 317

Query: 287 LGYTPAVARDENVWFASSLDEAA-----RLACLLSRVTARRNAIAPVSSGFICGLYTGGT 341
           +G       +      ++L   A     + A   +          P S+  I GL++GGT
Sbjct: 318 VGPNHPTLTESAEHILTALGHQAPQPWPQWAPTATTAAVATTEPMPPSAPMIRGLFSGGT 377

Query: 342 LAAEAAGLLAGHLGVEADDTHQHG 365
           L AEA  +L    G   D+    G
Sbjct: 378 LRAEAEVVLTRAGGQMIDNQRSGG 401



 Score = 72.9 bits (177), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 51/140 (36%), Positives = 66/140 (47%), Gaps = 4/140 (2%)

Query: 343 AAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIA 402
           A E+       LG                   + D GDD YT GRPHPMID TLR++ +A
Sbjct: 469 APESPDAADERLGTAPHAHATAATAAAFAFD-LTDFGDDAYTRGRPHPMIDNTLRSRGVA 527

Query: 403 DLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQ 462
           +  A  +V V+LLDVV+G GA ADP A + +A   A   R     L  + ++ G   DPQ
Sbjct: 528 EAAADERVGVVLLDVVLGRGAHADPGAEIAAAIGAARGVRA---GLAVVVSLCGAAGDPQ 584

Query: 463 CRSQQIATLEDAGIAVVSSL 482
              +Q   L  AG  V  S 
Sbjct: 585 GLGRQAGVLAGAGAWVFLSN 604


>UniRef50_C6E214 CoA-binding domain protein n=3 Tax=Geobacter RepID=C6E214_GEOSM
          Length = 697

 Score =  227 bits (578), Expect = 9e-58,   Method: Composition-based stats.
 Identities = 66/517 (12%), Positives = 149/517 (28%), Gaps = 61/517 (11%)

Query: 65  CVAIRSEAADAGIAQA-IMQQLEEALKQLAQG--SGSSQALTQVRRWDSACQKLPDANLA 121
            VAI   +         I++ L+    +      + ++  +  ++ + +  +     +LA
Sbjct: 12  AVAIVGASTKELSIGNVIIRNLQRYGYRGKIYPLNPNAPEVCGLKAYKTLDEIPDQIDLA 71

Query: 122 LISVAGEYAAELANQALDRNLNVMMF-SDNV------TLEDEIQLKTRAREKGLLVMGPD 174
            + +  ++  +   +   + +  ++  S           + +     R  E G+ V GP+
Sbjct: 72  HVIIPSQFVPQTIEECGKKGIKAVIINSAGFCELGEEGAQLQDDFLRRGEEFGVRVFGPN 131

Query: 175 CGTSMIAGTPL----AFANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
           C   + +   L     F    P  G++ V+  SG     +   +A  G G       G  
Sbjct: 132 CQGIINSDPALKAYCNFTFTFPEPGHVSVVALSGGVGALIMQALADLGVGQRFYASNGN- 190

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
                   IS    L     DE +  +   ++          V    A  KP +A+  G 
Sbjct: 191 -----ACDISVTEILSYYGEDEGTRAVVLYTEGFPNPGEFLAVAREVAAKKPILAMKAGR 245

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTAR---------RNAIAPVSSGFICG----- 335
           T   A+  +    S          +  +             R A+A  +     G     
Sbjct: 246 TEQGAKAASSHTGSLAGVDIATELIFEKTGILSFIDEGEMARAAMAFATQPIPRGNRVGI 305

Query: 336 -LYTGG--TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI 392
              TGG   +A +        +   + ++ +           + +  D   T G      
Sbjct: 306 ITNTGGPAVIATDVLVSCGLDVPKLSPESIERLRPSQLPEAALENPIDVVATAG------ 359

Query: 393 DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIA 452
                   +    ++  +  + ++ V       D          +             + 
Sbjct: 360 -GAQFRGALDLFLSEEGIDSIFINFVTAPFTDTD-------EVARQIVEVNRLARKPIVC 411

Query: 453 TVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA----QQHTPSLL 508
               T+   +   +    L++ G+ + ++  +A     AL                 S +
Sbjct: 412 NFM-TDLSQERFRKTRDILKEGGVPIYANPSDAAKALGALAQYGRLRRRDIGSPQKASGV 470

Query: 509 ENVA---VINIGLRSFALELQSASKPVVHYQWS-PVA 541
           +      VI+         L +     +   ++ PVA
Sbjct: 471 DAARAQAVIDRARDEGREVLSATDVYTIFEAYAIPVA 507


>UniRef50_C8S7L3 CoA-binding domain protein n=1 Tax=Ferroglobus placidus DSM 10642
           RepID=C8S7L3_FERPL
          Length = 459

 Score =  227 bits (578), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 66/462 (14%), Positives = 142/462 (30%), Gaps = 43/462 (9%)

Query: 66  VAIRSEAADAGIA--QAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALI 123
           VA+     +       A+   ++    ++   + +   +  V+ + S        +LA++
Sbjct: 15  VAVIGATKNPKKMGFHALNSLVKTFKGKIYAVNPNYDEILGVKAYRSVKDLPETPDLAIL 74

Query: 124 SVAGEYAAELANQALDRNLNV-MMFSDNV-------TLEDEIQLKTRAREKGLLVMGPDC 175
           +V  +       + L++     ++ S            E   +LK        +V+GP+ 
Sbjct: 75  AVPRDAIYNSVRELLEKGCRAFVIISAGFREAEIADGEELHKKLKELVDSYNAVVIGPNT 134

Query: 176 GTSMIAGTPLAFA-----NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
              +     L  +     +++ +G+I +I  SG     +       G G +  +GLG R 
Sbjct: 135 FGMVNLKADLNASFTPALSLLKKGDIALISQSGGVCHLIAPYSMREGIGFSKIVGLGNRL 194

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
                  +     LE L  D++++ +A   +   E  +L       +  KP VA+  G  
Sbjct: 195 ------NVDFHDMLEYLKDDKETKSIALYIEGIDEPKKLCEKIREVSRVKPVVAMKAGRF 248

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLY-----TGGTLAAE 345
               +       S           L +  A           F   L       G  +A  
Sbjct: 249 EKADKASKSHTGSMAGNYKLYVSALKQHGAVIAEDLIELVSFAKALAMQKPMKGDRVAVI 308

Query: 346 AAGLLAGHLGVEADDTHQHGMM--LDADSHQIIDLGDDFYTVGRPHPMI----DPTLRNQ 399
           +     G +  +  +     +    +    QI ++   +     P  +     D     +
Sbjct: 309 SLVAGLGMVASDYCELKGLKLAKFTEETQKQIYEILPPYTIRDNPIDLGFVANDTKTCGE 368

Query: 400 LIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTER 459
           +I        V   +++ +  +  + +       A  KA      ++       +     
Sbjct: 369 VIELAVGDENVDGAVINYIFSW--SEEFLEVPTKAIIKA------SKEKPLTMCLNYPPG 420

Query: 460 DPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQ 501
                 ++   LE  GI V S+   A     AL        +
Sbjct: 421 FWDDVKEE---LESNGIPVFSTPEIAAKSLWALREYDKRVRE 459


>UniRef50_O28341 Putative uncharacterized protein n=3 Tax=Archaeoglobus fulgidus
           RepID=O28341_ARCFU
          Length = 673

 Score =  227 bits (578), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 64/467 (13%), Positives = 141/467 (30%), Gaps = 56/467 (11%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALK--QLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +   G     I+  L++     ++   + ++  + +++ + S      + ++A+
Sbjct: 227 VAVIGASRTVGKPGFNIVWNLKQNGFMGKIYPVNPNADKILELKCYPSILDIPDEVDMAI 286

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLED------EIQLKTRAREKGLLVMGPDC 175
           I+V  +   E+  +   + +   ++ S   + E       E ++   A++ G+ + GP+ 
Sbjct: 287 IAVPAKIVPEVMAECAQKGIKGAVIVSSGFSEEGEKGAEYERRVLEIAKKHGIRIFGPNT 346

Query: 176 GTSMIAGTPLAFANVMPE----GNIGVIGASGTGIQELCSQ--IALAGEGITHAIGLGGR 229
              +        +  +      GNIG+I  +G  +  +           G +  +G+G +
Sbjct: 347 TGVLNTENGFITSFAIQPVIKKGNIGIIAQTGLFLGIMMDIVTSNHPSIGFSKIVGMGNK 406

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
               +         L+ L  DE+++V+    +           +   +  KP V    G 
Sbjct: 407 IDVEDY------EVLDFLLKDEQTKVIGIYMEGIKNGRAF--YDVASSAEKPIVVFKSGR 458

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARRN---------------AIAPVSSGFIC 334
           T    +      AS   +      +  +    R                   P       
Sbjct: 459 TEYGQKAAMSHTASICGDDDVFDAVCRQANLVRVYSFDELFDVTKAFSLQPLPKGDRVAI 518

Query: 335 GLYTGGTL--AAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI 392
             YTG      ++AA      L   + DT      +  + H +    +            
Sbjct: 519 IHYTGSGCVQGSDAAYFAGLKLAEFSKDTVDKISEVTPEWHNV---NNPIDIWPMVEYYG 575

Query: 393 DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIA 452
                   I  +     V  ++  V          A  L++A  +     L         
Sbjct: 576 AFKAYQTAIEAVMEDEGVDSVIACV---------WANRLINADFEPDYKSLKKYGKPIYF 626

Query: 453 TVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPA 499
            V G              LE  GI V +++  A  +   +       
Sbjct: 627 CVEGARDVVFDHKNA---LELNGIPVYTNVINAVNVLGKVTKYAKRR 670


>UniRef50_B8FN91 CoA-binding domain protein n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FN91_DESAA
          Length = 694

 Score =  227 bits (578), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 74/540 (13%), Positives = 151/540 (27%), Gaps = 77/540 (14%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQL-AQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
           VA+           AI+  L +  K      +    ++  ++ + S        +LA++ 
Sbjct: 12  VAVIGATNKPKGGLAIVVNLIKGFKGGIYPINPGYDSILDLKCYPSVKDVPDPVDLAILF 71

Query: 125 VAGEYAAELANQALDRNLNVMM-----FSDNVTLE--DEIQLKTRAREKGLLVMGPDCGT 177
           V  +   ++  +  +R +  +M     FS+        + ++   A+  G+ V GP+C  
Sbjct: 72  VPAKAVPKMVEECGERGIRAVMIQSAGFSETGPEGKALQDEVDAVAQRHGIRVWGPNCLG 131

Query: 178 SM--IAGTPLAFANV------MPEGNIGVIGASGTGIQE-LCSQIALAGEGITHAIGLGG 228
            +  +     +FA           GN+ +I  SG      L   ++    G++    +G 
Sbjct: 132 MVDSVNHNVFSFAAPSMWDVGHIPGNVSLIVQSGMLAGGFLIDNMSHGTMGMSKVCSIGN 191

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG 288
           +        +     LE L +D  ++ +    +        +     + + KP V L  G
Sbjct: 192 K------SDVDECDLLEYLISDPDTQAIGMYLEAI--PRGRRFAELCRQSPKPIVVLKGG 243

Query: 289 YTPAVARDENVWFASSLDEAARLACLLSRVTARRNA-------------IAPVSSGFICG 335
            + A A+      AS   + A ++ +L++                    I P     + G
Sbjct: 244 TSTAGAKAAASHTASMSGDGAIVSGVLAQCGVVEARDFKQMLDICRAFGITPEMPPEMRG 303

Query: 336 LYTGGTLAAEAAGLLAG----------HLGVEADDTHQHGMMLDADSHQIIDLGDDFYTV 385
                T +  A  + A            L  E+ D               +DL       
Sbjct: 304 RTAILTYSGGAGIMAADFVENFGLEVAELSQESKDAMAQVYPDWMPVANPVDLWPSVEKN 363

Query: 386 GRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDN 445
           G              +  +   P V ++ L            +  L+             
Sbjct: 364 GAVK------TFTTAMNAVCKDPGVDMIFL--------HLHASGGLLVMDIGELIDMAKE 409

Query: 446 QPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI-----HPLSPAA 500
                   + G     +        L   G      L  A    + ++        +P  
Sbjct: 410 AGKPIFCWLIGQMEPARDMHILAQKL---GAPTYRELSRAVESMSTVLGWYKSRAAAPCG 466

Query: 501 QQHTPSLLENV-------AVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLER 553
               P  ++             +   +    L +   PVV    +         A  L  
Sbjct: 467 VDFRPEPVKARCRALLDGRRGALDEHASKQILAATGIPVVQEILAAGQDQAVTAAEKLGY 526


>UniRef50_A8ZSQ9 CoA-binding domain protein n=1 Tax=Desulfococcus oleovorans Hxd3
           RepID=A8ZSQ9_DESOH
          Length = 516

 Score =  226 bits (577), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 62/396 (15%), Positives = 120/396 (30%), Gaps = 49/396 (12%)

Query: 66  VAIRSEA---ADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +   A  G   AI   L     +L   +    ++  V  + S      + +LA+
Sbjct: 29  VALIGASNNVAKWGGIVAINLILGGFKGKLYPVNPKEASVHGVPAFASVKDIQDEIDLAV 88

Query: 123 ISVAGEYAAELANQALDRNLNV-MMFSDNVTLEDEI------QLKTRAREKGLLVMGPDC 175
           I V      ++ +  +D+ +   ++ +       E       ++  RAR  G++++GP+ 
Sbjct: 89  IIVPAAGVPDIISDCVDKGIGAAVVITSGFGELGEEGKGLQNEMLRRARAGGMVLVGPNG 148

Query: 176 GTSMIAGTPL---AFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
                  +             G IG+   SG    EL  Q+A  G G +  I  G     
Sbjct: 149 QGIAAPESKFYPWFPTFRPDPGVIGIASQSGGISTELSEQLAEFGFGCSKVISTGN---- 204

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                +S    L     D  ++V+    +   +           A  KP + +  G T  
Sbjct: 205 --CADLSWPDYLAYFRQDPSTKVVLLYMEGAQDGRAFFREAKKTALEKPVILIKSGRTQE 262

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRNAIAP--------------VSSGFICGLYT 338
             R  +    S     A    +  +    R                        +C L  
Sbjct: 263 GGRAASSHTGSMAGSDAVFDGVCKQAGLIRAKTLEEAVVLAAAFVTTPLPRGRRVCVLTG 322

Query: 339 G---GTLAAEAAGLLAGHLGVEADDTHQHG---MMLDADSHQIIDLGDDFYTVGRPHPMI 392
           G   G L A+A       L   ++ T +     +      +  +D+             +
Sbjct: 323 GGGQGVLTADALAARGLTLPPLSEATVKKLREQLPAWWHPNNPVDM----------VAGL 372

Query: 393 DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPA 428
                 ++I  L        ++ + +    +  DP 
Sbjct: 373 GYGGPTEIIPILMESDDFDGIIFNGIGWIYSMVDPV 408


>UniRef50_Q2LV26 Acetyl-CoA synthetase n=1 Tax=Syntrophus aciditrophicus SB
           RepID=Q2LV26_SYNAS
          Length = 482

 Score =  226 bits (577), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 62/490 (12%), Positives = 136/490 (27%), Gaps = 60/490 (12%)

Query: 41  ANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQ 100
            NK  +             +P+ + V   S + D      +   +     ++   +    
Sbjct: 10  NNKEEIKHM-MTQKLVKLFSPDSVAVIGASNSFDKLGYHVMKSLVGHYAGKIYPINLKGG 68

Query: 101 ALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLED---- 155
            +  +  + S  +   + +LA+I V      E  +Q   + +   ++ +      +    
Sbjct: 69  KVWNLDSYASLAEVPGNIDLAIIVVPAALVPETLHQCGGKGVKGAVLITAGFREIEDSQG 128

Query: 156 ---EIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANV-----MPEGNIGVIGASGTGIQ 207
              + +++    +  + ++GP+          +  +       + +G + +I  SG    
Sbjct: 129 GVLQERIRKICDQYEMPIIGPNTSGFANIAFGIDASFTSEFCELEKGGVAIISQSGGLCH 188

Query: 208 ELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEML-SADEKSEVLAFVSKPPAEA 266
                      G++  + LG R        +    A+      DE ++V+A   +   E 
Sbjct: 189 LCGFLALHQRMGVSSLMSLGNRL------NVGFPEAVRFFIEEDEATKVIALYIEGLDEP 242

Query: 267 VRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIA 326
             L  +       KP VA   G +            S             +        +
Sbjct: 243 RELLDMARSLRGKKPIVAYKSGKSAKSDSASKFHTGSLAGNHEIWKGAFRQAGILEVTSS 302

Query: 327 PVSSGFICGLYT-----------------GGTLAAEAAGLLAGHLGVEADDTHQHGM--- 366
                    L +                  G +AA+A       L   +  T +      
Sbjct: 303 EELIDTAKVLDSCALARGNRITVLSGQAGPGIIAADALEAYGLSLSQFSAATKEKINEYL 362

Query: 367 MLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATAD 426
                    +D+G        P  M D      ++  +        ++   +  + +   
Sbjct: 363 PPIVIRTNPVDMGP---VWYNPKAMFD------ILNAVIEDEGTDGVI--FINLYASANL 411

Query: 427 PAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATL-EDAGIAVVSSLPEA 485
             AS ++   K   A         I  +T     P      I  L    GIA++ +   A
Sbjct: 412 SLASAMAEHIKNIDAFK----KPVIGVITAP---PGVWDDGIKRLDRKKGIAILPTPERA 464

Query: 486 TLLAAALIHP 495
               + L   
Sbjct: 465 AKAMSNLWKA 474


>UniRef50_B3PB71 Acetyltransferase, GNAT family n=1 Tax=Cellvibrio japonicus Ueda107
           RepID=B3PB71_CELJU
          Length = 826

 Score =  226 bits (576), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 68/497 (13%), Positives = 137/497 (27%), Gaps = 51/497 (10%)

Query: 66  VAIRSEAADAGI-AQAIMQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   +        A+M+ L +          +   +++  V  + S  +     +LA+
Sbjct: 15  IAVIGASNQPNRPGNAVMRNLLQGGFDGPIMPVTPHYKSVNGVLAYRSIDELPLVPDLAV 74

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNV-------TLEDEIQLKTRAREKGLLVMGPD 174
           I         +  Q   +     ++ +  +           + Q+   AR+ G+ ++GP+
Sbjct: 75  ICTRATRVPAIILQLGRKGTRAAIVIAAGLNRLHTAQGTNLQEQMLAIARQWGVRILGPN 134

Query: 175 CGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
               M+ G  L  +        G I  +  S      L         G +H + LG    
Sbjct: 135 SLGLMVPGIGLDASYAHTRARAGKIAFVSQSSAVCVTLLDWAKRRRIGFSHVVALG---- 190

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
             +   +     L+ L  D  +  +        +           +  KP + +  G   
Sbjct: 191 --DGTDVDFDEMLDYLGRDANTSAILLYIDHIHQGRAFMSAARAASFNKPILVIKTGAQL 248

Query: 292 AVAR-----DENVWFASSLDEAARLACLLSRVTARRNAIA---------PVSSGFICGLY 337
                            ++ +AA     + RV   R  +A         P+    +  L 
Sbjct: 249 ENQMLISHLPMEQLGLDAVYDAAIKRAGMLRVGDLRELLAAVETLANGKPIQGEQLVILA 308

Query: 338 TGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLR 397
            G   +A A  +L+   G  A         L A  H      +    +G       P   
Sbjct: 309 NGNAPSAMALDVLSQRGGRLAVLEPGIVDALHAVIHNGGRATNPINLLGDA----SPEDY 364

Query: 398 NQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACA--ARLDNQPLY-AIATV 454
            Q +  L     +  LL   ++   +   P  +             + +   L   +   
Sbjct: 365 RQALQVLLRSNAIDNLL---IMHAPSALIPGETYAQVVIDTLREHRQKNGARLPNVLVNW 421

Query: 455 TGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA-QQHTPSLLE--NV 511
            G +       +      DAGIA   +          ++           TP  +     
Sbjct: 422 MGEDAAV----EARQRFADAGIASFRTPEGVVGAFMHMVQYRRNQKLLSETPESISDWAP 477

Query: 512 AVINIGLRSFALELQSA 528
               +        LQ  
Sbjct: 478 HQPEVAQTLIDQALQER 494


>UniRef50_B3LBB6 Acetyl CoA synthetase, putative n=1 Tax=Plasmodium knowlesi strain
           H RepID=B3LBB6_PLAKH
          Length = 995

 Score =  226 bits (575), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 68/512 (13%), Positives = 151/512 (29%), Gaps = 63/512 (12%)

Query: 18  MIISRKLSESENVDDV-SVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAG 76
           MI+S++ +    + +  SV +G   N   ++   F +       P    + +      AG
Sbjct: 1   MILSKRSNRLSVLRNYYSVWVGYNQNVQQVEN--FKNSLNYLFKPKS--IGVIGATERAG 56

Query: 77  IAQ-AIMQQLEEA--LKQLAQGSGSSQALTQVRRWDSACQKLPD-ANLALISVAGEYAAE 132
               +I++ L +     +L   +     +     + +      +  +LA+I+V   +   
Sbjct: 57  SVGNSIVKNLMQGEESYKLYFVNSKGNKVYNRDSYKTIGDVPEENIDLAVIAVPRNHVLG 116

Query: 133 LANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDCGTSM--IAGT 183
           +      +N+  ++        + +   + E Q+   A+  G+ ++GP+C   +      
Sbjct: 117 VMKDLKSKNVKGVVIVTAGFKETGSEGTKLEQQIIDVAKTNGIRIIGPNCLGIIHSYHNM 176

Query: 184 PLAFA-NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALT 242
             +FA N + +GN  ++  SG               G +H I +G       +  +    
Sbjct: 177 NASFADNTILKGNFSLLSQSGAICSAALDLSLQHNIGFSHFISVG------SMCDVQFYE 230

Query: 243 ALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFA 302
            +E L  DE ++ +    +   +  +   V       KP + L  G T   A        
Sbjct: 231 LVEYLFYDENTKYILLYVESIGDMNKFMAVCKKVCLYKPIILLKSGKTAKAAEAAISHTG 290

Query: 303 SSLDEAARLACLLSRVTARRNAIAPVSSGFICGLY-----------------TGGTLAAE 345
           S +         + ++                 L                    G L  +
Sbjct: 291 SMVGNYEIFYASMKKLGVLVVDNFEELFNMCKILNLSKYPETNEVCVVTNAGGPGVLLVD 350

Query: 346 AAGLLAGHLGVEADDTHQHGM---MLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIA 402
                 G+L    D+  +               +D+  D            P L  + I 
Sbjct: 351 NITRNDGNLSKLNDNLKKKLDAFLPPSWSKANPVDILGDA----------SPLLYKKTIE 400

Query: 403 DLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQ 462
            L    Q + ++  +++   +  +P  +            + N+    +    G      
Sbjct: 401 ALLKDEQFKNII--ILLSPQSVTEPMNTAKEIIS--VKDDMANKGKLLLCNYLGG----V 452

Query: 463 CRSQQIATLEDAGIAVVSSLPEATLLAAALIH 494
              +    L    I        +      L  
Sbjct: 453 SLEESTNFLNKNNIPTFIHPEHSAQNLLKLYK 484


>UniRef50_B4RED1 Acetyl-CoA synthetase / acetyltransferase (GNAT) family protein n=2
           Tax=Alphaproteobacteria RepID=B4RED1_PHEZH
          Length = 889

 Score =  225 bits (573), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 72/460 (15%), Positives = 130/460 (28%), Gaps = 60/460 (13%)

Query: 65  CVAIRSEAADAGIAQAI-MQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLA 121
            +A+   +   G    +  + L+           +   + +     + S        +LA
Sbjct: 14  AIALIGASDRPGSVGDVVARNLKAGGFPGPLMFVNPKGKTILGETAFRSVADLPHAPDLA 73

Query: 122 LISVAGEYAAELANQALDRNLNV-MMFSDNVTLEDE------IQLKTRAREKGLLVMGPD 174
           +I+        L +    R     ++ S     +DE        L   AR   L ++GP+
Sbjct: 74  VIATPAPTLPGLVSDLGARGCRAAVVISAGFEAQDEATARLRQALLDAARPHLLRIVGPN 133

Query: 175 CGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
           C   M     +  +      P G + ++  SG     L       G G +H + LG    
Sbjct: 134 CLGFMSPRRGINASFARGSAPPGGVALVAQSGAVASALLDWAPAHGVGFSHVVTLGN--- 190

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
                 +     L+ L  D +++ +    +   EA +        A  KP V +  G   
Sbjct: 191 ---ALDVDVADMLDHLGRDPETKAILLYLEGLREARKFMSAARFAARSKPVVVIKGGRGA 247

Query: 292 AVARDENVWFASSLDEAARLACLLSRVTARR--------------NAIAPVSSGFICGLY 337
           A A+       +     A  A    R    +                  P S   +  + 
Sbjct: 248 AGAKAAFSHTGALAGADAVYAAAFRRAGLLQVAELSDFLEAAETFARGHPRSVERLAIVT 307

Query: 338 TGGTLAAEAAGLLAGHLGVEADDTHQHGMML-------DADSHQIIDLGDDFYTVGRPHP 390
            GG     A   L       A+ + Q    L        +  + +  LGD          
Sbjct: 308 NGGGAGVLAVDALEREGAPLAELSPQTIEALGRVAPANWSRRNPVDILGDTPA------- 360

Query: 391 MIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYA 450
                L  + ++ L A P+V  +L   +    A  D   +  +             P   
Sbjct: 361 ----QLYGEAVSILAAAPEVDAIL--AINCPTAVTDSTEAAEAVIAATP---RGWAPKPV 411

Query: 451 IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAA 490
           +    G        +Q  A     G+    +   A    A
Sbjct: 412 LTAWLGGA----SVAQARARFTAEGLPTYETPEAAVRAFA 447


>UniRef50_C8QZV8 CoA-binding domain protein n=2 Tax=Desulfobulbaceae
           RepID=C8QZV8_9DELT
          Length = 699

 Score =  225 bits (573), Expect = 4e-57,   Method: Composition-based stats.
 Identities = 80/460 (17%), Positives = 138/460 (30%), Gaps = 61/460 (13%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   +   G     I+  L            +  +  +  +  W +        +L +
Sbjct: 13  IAVIGASRTPGKVGHDILANLIAGGFAGRVLPVNPVADEILGLPCWPTLKGAGAQIDLGV 72

Query: 123 ISVAGEYAAELANQALDRNLNVM-MFSDNVTLED------EIQLKTRAREKGLLVMGPDC 175
           I+V      E     L      + + +      D      E +L  R R++ + ++GP+C
Sbjct: 73  IAVPRSLVEEAVEDCLAAGARAVAVITAGFKEMDATGAELEKKLAARCRQQQVRLLGPNC 132

Query: 176 GTSMIAGTPLA--FANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
              + +   L   FA  MP  GNI VI  SG     +    A    G+   + +G +   
Sbjct: 133 LGLINSHHRLNASFAGEMPACGNISVISQSGALATAILDLAAERHLGLAKLVSIGNK--- 189

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                ++ +  L  L+ DE++ V+    +  +            +  KP + L  G T A
Sbjct: 190 ---ADLNEVDLLSALTDDEQTGVIVAYLEDISSGDDFVKAATEASNHKPVIILKSGTTEA 246

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRN---------------AIAPVSSGFICGLY 337
             +                     R    R                   P     +    
Sbjct: 247 GRQAATSHTGVLAGADIAYGAAFRRAGVIRADTFESLFDCATALAMQPLPRGPRVLIITN 306

Query: 338 TG--GTLAAEA---AGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI 392
            G  GT+AA+A   AGL    L        +  +   A     ID+  D           
Sbjct: 307 AGGPGTMAADAVEQAGLQVAMLDKNTAAALKEKLPRAASVGNPIDVLGDA---------- 356

Query: 393 DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIA 452
           +P      +      P V  ++  V++   A   PAA    A   A            +A
Sbjct: 357 EPERYAAAVTAAQDDPAVDAIV--VILTPQAMTQPAA-TARAITSALK-----GDKPVLA 408

Query: 453 TVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAAL 492
              G       R++    L  AG+    S   A     A+
Sbjct: 409 AFMGGVEVMPGRTE----LVAAGLPDYPSPERAITALKAM 444


>UniRef50_Q1QWA2 CoA-binding n=1 Tax=Chromohalobacter salexigens DSM 3043
           RepID=Q1QWA2_CHRSD
          Length = 915

 Score =  224 bits (571), Expect = 7e-57,   Method: Composition-based stats.
 Identities = 64/469 (13%), Positives = 127/469 (27%), Gaps = 64/469 (13%)

Query: 66  VAIRSEAADAGIAQA-IMQQLEEALKQLA---QGSGSSQALTQVRRWDSACQKLPDANLA 121
           VA+   +         ++  L EA    A           +  V             +LA
Sbjct: 15  VAVIGASEKPHSMGGMVLGNLLEAGFPGALWAVNPSGYATVHGVSCVRRIGDLPAIPDLA 74

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEI---------QLKTRAREKGLLVMG 172
           ++    E             +   +     +  D+          ++   AR  G+ V+G
Sbjct: 75  ILCNPVEGVPRSIEALGKLGVRAALVLSGGSYLDDRTQDGGSLRERMLKAARRSGIRVLG 134

Query: 173 PDCGTSMIAGTPLAFANVMPE---GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
           P+C   ++ G  L           G +  +G SG     +    A  G G +H + LG  
Sbjct: 135 PECLGIVVPGKKLNATYASQPIKAGRVAYLGQSGMLGNAMIDWAAGRGIGFSHLVTLG-- 192

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
               +   +     ++ ++    +  L    +   +A          +  +  +A+  G 
Sbjct: 193 ----DSVDVMLSDLMDYINQYSPTRALLLHLERVHDAQHFMTALRDASRNRLVLAIKSGR 248

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARRN--------------AIAPVSSGFICG 335
           +     D         +        L+R    R                + P+    +  
Sbjct: 249 SAQSTLDHETQTPGIDNRDVVFDAALARAGVVRVDNSDELFDALETLTRMRPLRGDRLAI 308

Query: 336 LYTG---GTLAAEAAGLLAGHLGVEADDTHQHGMMLD----ADSHQIIDLGDDFYTVGRP 388
           +  G     LA +   +  G L      T    +  +          +DLG +       
Sbjct: 309 VSNGLGPALLAIDKLVMAGGKLAELTAATRDALIAGEFDVSMPGRNPVDLGGNA------ 362

Query: 389 HPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPL 448
                P    + +  + A  QV  +L   V+       P+ +   A          N   
Sbjct: 363 ----SPERFVEALEIVAADTQVDAVL---VVHAPTRMAPSKTTAEALIANRKRFKRN--- 412

Query: 449 YAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLS 497
             + +  G       R +       AGI    S  +A      ++    
Sbjct: 413 -LLTSWMGLAEALDARHEC----NLAGIPTYISPEKAVKAFMHMVDYQR 456


>UniRef50_A9A1Y1 CoA-binding domain protein n=6 Tax=Thaumarchaeota
           RepID=A9A1Y1_NITMS
          Length = 698

 Score =  224 bits (571), Expect = 7e-57,   Method: Composition-based stats.
 Identities = 75/542 (13%), Positives = 158/542 (29%), Gaps = 85/542 (15%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQV--RRWDSACQKLPDANLALI 123
           +A+   +   G   A +        +      S    T    + + S        +LA+I
Sbjct: 12  IAVIGASDKRGSVGATITSNIMNGFKGTVYPISPTRDTVFYKKAYKSVLDVPKSIDLAVI 71

Query: 124 SVAGEYAAELANQALD----------RNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGP 173
            +       +  +                  +   D    + E Q+   A++  + V+GP
Sbjct: 72  VIKNTLVTPVLEECGKKKIKGVIIITAGFKEV---DEEGAKREQQVIDIAKKYNMQVVGP 128

Query: 174 DCGTSMI----AGTPLAFANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
           +C   M           F  V P+ G I ++  SG     L    +  G G +  + LG 
Sbjct: 129 NCLGVMNLDSKTMMNSTFLKVTPKSGKIALVSQSGAICAALVEDASAQGIGFSAVVSLGN 188

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIV--NAMKATGKPTVALF 286
           + +  EV        L++L+  +++EV+    +   +      V  N  K   KP + L 
Sbjct: 189 KAVMSEV------DVLKILANHKQTEVIVMYLEDMGDGQEFLKVCKNITKKLKKPVLVLK 242

Query: 287 LGYTPAVARDENVWFASSLDEAARLACLLSRVTARRN---------------AIAPVSSG 331
            G +P  A+       + +        LL +  A R                   P +  
Sbjct: 243 SGRSPEGAKAAMSHTGALMGSDEIYDALLKQSGAIRVDTMEELFDYATAFSKQPLPSNGD 302

Query: 332 FICGLYTGG--TLAAEAAGLLAGHLGVEADDTHQ--HGMMLDADSHQIIDLGDDFYTVGR 387
            +     GG   ++ +A       +        +    +     S   +D+  D      
Sbjct: 303 LVIVSNAGGPAIISTDACSKAKIKMADITSIRKKIDEVIPPWGSSRNPVDIVGDA----- 357

Query: 388 PHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASL-VSAWQKACAARLDNQ 446
                D    + ++  +   P+V  ++        +   P+ +L      +         
Sbjct: 358 -----DFNRFHNVLDRVLKHPKVGSVI--------SMCTPSGTLNYDKLAEVIVEMSKKY 404

Query: 447 PLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH------------ 494
               +A++ G +            L D  +   +    A    AA+I             
Sbjct: 405 KKTMLASLMGLDEGVTN----REILADGNVPYYTYAEGAIRTLAAMIRFSDWVKSSPGKI 460

Query: 495 ---PLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLL 551
               ++ A  +     ++     N+        L++   P+     +       K A+ +
Sbjct: 461 TKFKVNKAKAKKIFDQVKKEKRPNLLEEEGQEVLKAYGLPLPKSTLAKNEAEAVKAAKKI 520

Query: 552 ER 553
             
Sbjct: 521 GY 522


>UniRef50_D2B5B2 Acyl-CoA synthetase (NDP forming)-like protein n=1
           Tax=Streptosporangium roseum DSM 43021
           RepID=D2B5B2_STRRD
          Length = 883

 Score =  224 bits (570), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 67/459 (14%), Positives = 136/459 (29%), Gaps = 65/459 (14%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQLAQGSGSSQA--LTQVRRWDSACQKLPDANLAL 122
           VA+       G     I++ L +          +  A  +  +  + +        +LA+
Sbjct: 198 VAVIGAGRAPGGVGHRILRNLLQGGFPGPVYPINPHARQICGLPVYANVGSVPGPIDLAV 257

Query: 123 ISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           I+       E+A       +  ++     F++      + +L    RE G+ ++GP+C  
Sbjct: 258 IATPARTVPEIARDCAGHGVRNVVVVTSGFAETGGTSAQDELLRICREAGMRLVGPNCLG 317

Query: 178 SMIAGTPLA---FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSRE 234
            +     L      +    G + ++  SG     L  +      GI+    +G +     
Sbjct: 318 IVNTAARLNAGFLPHPPAPGRLALMSQSGAVAVALIDRANHLEIGISSFASVGNK----- 372

Query: 235 VGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVA 294
              +S    LE    D  ++V+    +      R   +    +  KP +A+  G   +  
Sbjct: 373 -ADVSGNDLLEYWEDDPATDVITLYLESFGNPRRFGRIARRVSRRKPIIAIKSGRGGSGE 431

Query: 295 RDENVWFASSLDEAARLACLLSRVTARRN---------------AIAPVSSGFICGLYTG 339
           R      A++      +  LL      R                   P          +G
Sbjct: 432 RAVRSHTAAAATPDVAVDALLKASGVIRVETVRDMLDTARLLATQPLPQGRRVAIVGNSG 491

Query: 340 GT--LAAEA---AGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDP 394
           G   LAA+A     LL   L        +  + + A     +DL                
Sbjct: 492 GPQALAADACEQRDLLVPELAPVTRGRLRSRLPVAAAVANPVDLTAGGSAQ--------- 542

Query: 395 TLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATV 454
                 I  + A P +  +++     FG+        +   ++A A    +      A +
Sbjct: 543 -ELAFAIETVLADPGIDTVMVVYTPPFGSG-------LGRTRQAIARAAMSAGKTVTACI 594

Query: 455 TGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
           +G +            L D  +   +   +A       +
Sbjct: 595 SGHDG-----------LLDGRVPCYAFPEQAVQALRHAV 622


>UniRef50_C1XWJ3 Acyl-CoA synthetase (NDP forming) n=2 Tax=Meiothermus
           RepID=C1XWJ3_9DEIN
          Length = 775

 Score =  224 bits (570), Expect = 9e-57,   Method: Composition-based stats.
 Identities = 77/474 (16%), Positives = 138/474 (29%), Gaps = 79/474 (16%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQA----------------LTQVRRW 108
           VA+   + D       +++ L            +  A                +  +  +
Sbjct: 211 VAVVGASRDPQSVGYRVLENLVSNRFAGPVYPVNPAASQVTAGSAQANGEVLVVGSILAY 270

Query: 109 DSACQKLPDANLALISVAGEYAAELANQALDRNLNV-MMFSDNVTLEDEIQLKTRAREKG 167
            S        +LA+I+V  +     A     R +   ++ +  +       L    R  G
Sbjct: 271 PSVKAIPGPVDLAVITVPPDQVIAAAESCGQRGVRALVVVTVGLCAGQIKSLGEVCRSYG 330

Query: 168 LLVMGPDCGTSMIAGTPL----AFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHA 223
           + ++GP     +     +      A + P G + +   SG     +       G GI+  
Sbjct: 331 MRLVGPGSLGLVHTHPEVRLAAGLAGMPPRGRLALSSQSGALGLAVLEYAREMGLGISSF 390

Query: 224 IGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTV 283
           + LG +        +S+   ++    D ++ V+    +      R   +       KP +
Sbjct: 391 VSLGAK------ADVSSNDLIQFWEDDPETGVILLYIENFGNPRRFARLARRVGRQKPIL 444

Query: 284 ALFLGYTP---AVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGG 340
            +  G  P   A+ +   V  A SL+E    A LL      +   A      +      G
Sbjct: 445 VVRPGRDPRVEALFQQTGVIRADSLEEVFDTAALL----TFQPLPAGPRVALVSNASGPG 500

Query: 341 TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQL 400
           TLA EA                              DLG              P+   + 
Sbjct: 501 TLALEALRSGG-------------------LEATHFDLGSTAT----------PSQYRET 531

Query: 401 IADLGAKPQVR-VLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTER 459
           IA L A P    V++L V +GF  T D AA+L  A       R        +A    T  
Sbjct: 532 IAQLLADPAYDAVMVLFVPMGFAPTEDVAAALAEA-------RRGETSKTLLACFM-TGG 583

Query: 460 DPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAV 513
            P+  + +        + V      A    + ++       +            
Sbjct: 584 RPRVFAGEER------VPVYRFPESAARALSLVVQYARWRREPPGEIPDFQPQE 631


>UniRef50_C6BU19 CoA-binding domain protein n=3 Tax=Desulfovibrionales
           RepID=C6BU19_DESAD
          Length = 902

 Score =  223 bits (568), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 77/540 (14%), Positives = 150/540 (27%), Gaps = 83/540 (15%)

Query: 66  VAIRSEAADAGIAQAIMQQ---LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+     D   A  I+ +       L  +   S  ++A++ V  +    +     +LA+
Sbjct: 15  VAVIGATNDPANAGNILMRNLMGGGFLGPVMPVSTDAEAISGVLTYKDVSELPKVPDLAI 74

Query: 123 ISVAGEYAAELANQALDRNLNVM--------MFSDNVTLEDEIQLKTRAREKGLLVMGPD 174
           I +  E    L  +  +  +              +N  +    +L   A    + ++GP 
Sbjct: 75  ICLPLEECPPLLERLRNIGVKACALIGPGFSAIPENERVRLRAELLRAANSPQMRILGPK 134

Query: 175 CGTSMIAGTPLAFANVMPE---GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
               ++    L  +        G I  +  S + I  +    A    G +H + LG R  
Sbjct: 135 SLGFIVPAMNLNASLAPLPAKAGKIAFVSQSDSFIPTVLDWAATNDIGFSHVVSLGSR-- 192

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY-- 289
                 ++    L+ L +D ++  +    +   +A          +  KP +A+  G   
Sbjct: 193 ----IDLTFGDVLDYLGSDAQTRSILLYIESIHDARDFMSAARAASRNKPVLAIRPGQAL 248

Query: 290 ---TPAVAR--DENVWFASSLDEAARLACLLSRVTARR----------NAIAPVSSGFIC 334
              T  +AR  +  +  A  + + A     + RV              +   PV    + 
Sbjct: 249 QHVTQELARLENAMIARADEVYDVAFRRAGMLRVQTIDGMFDAAQTLASLRQPVRGDRLA 308

Query: 335 GLYTG---GTLAAEAAGLLAGHLGVEADDTHQHGM---MLDADSHQIIDLGDDFYTVGRP 388
            +  G   G  AA+      G L   +DDT +        +      + +  D       
Sbjct: 309 IIVNGTSAGLAAADGLIRRGGKLAKLSDDTVEKLNTVFDGEWSGGNPVTIKFDTPGQ--- 365

Query: 389 HPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPL 448
                       +  L    +V  +L+            A    +   +  A  L     
Sbjct: 366 -------KYLDALKVLIKDKEVDAVLVV-------HVPFAGISSAEVAEILAKGLKRVRR 411

Query: 449 YAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA-------- 500
             + +  G++       +        GI    S  +A      +                
Sbjct: 412 MVLTSWLGSDMS----RKSRKIFSVHGIPTYESADQAVRAFMYMAEYQRNQELLTETPDS 467

Query: 501 --QQHTPSLLENVAVINIGLRSFALELQS---------ASKPVVHYQWSPVAGGNKKLAR 549
                 P        +   L     EL              PVV  + +  A      A 
Sbjct: 468 LPTDFFPDTTTARETVRKALSEGRQELNEPEARRVLAAYGLPVVETKVALSAREAVIAAD 527


>UniRef50_C9PHJ3 Protein acetyltransferase n=3 Tax=Gammaproteobacteria
           RepID=C9PHJ3_VIBFU
          Length = 895

 Score =  223 bits (567), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 77/498 (15%), Positives = 142/498 (28%), Gaps = 61/498 (12%)

Query: 66  VAIRSEAADAGIAQAI-MQQLEEALKQLAQGSGS--SQALTQVRRWDSACQKLPDANLAL 122
           VA+   +     A  I M+ L +     A    +    ++  V  + +        ++A+
Sbjct: 13  VAVIGASIRPFRAGNIVMKNLLQGGFDGAIMPVTPYYPSVCGVLAYKTIDALPLVPDIAI 72

Query: 123 ISVAGEYAAELANQALDRNL-NVMMFS------DNVTLEDEIQLKTRAREKGLLVMGPDC 175
           +         +  Q  D+ + NV++ S      D    E + Q    A+E G+ V+GP+ 
Sbjct: 73  LCTHASRNVTIFRQLADKGVSNVIVLSSDMYTLDAQGREIQEQCTAIAKESGMRVLGPNS 132

Query: 176 GTSMIAGTPLA--FANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
              ++        F+ V    GNI  I  S      +         G +  + LG     
Sbjct: 133 LGLILPWINFNGSFSPVTASRGNIAFISQSAAVCTTILDWANDKQIGFSAFVSLGN---- 188

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                I     L+ LS D+ ++ +        +A R        +  +  + L  G T A
Sbjct: 189 --ASDIDFSDLLDCLSTDKHTDAILLYVDTIKDARRFMSAARAASRNRRILVLKGGRTTA 246

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRNA--------------IAPVSSGFICGLYT 338
             +   +               + R    R                  P+    +  +  
Sbjct: 247 GRKAAQMHTGGDDTLDIIYDSAIRRTGMLRVNNTHELFAAVETLTHSVPLRGERLAIITN 306

Query: 339 GGTLAAEAAGLLAGHLGVEADDTH-------QHGMMLDADSHQIIDLGDDFYTVGRPHPM 391
           GG  A  A   L    G  A+          Q      + S+ I  +GD           
Sbjct: 307 GGGPAIMAIDTLLERGGKLAELEASVFETLNQCLPQSWSHSNPIDIVGD----------- 355

Query: 392 IDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAI 451
            D T     +  +     +  +L+       A +            A  A   +     +
Sbjct: 356 ADHTRYVNALNAVLDSDDIDAILIMHSPSAIAHS---EQTAQVIVDAIKAHPRSPRFNIL 412

Query: 452 ATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI-HPLSPAAQQHTPSLLEN 510
              +G                 AGI    +   A +    L+ +  +      TP+  E 
Sbjct: 413 TNWSGE----LTAKPARQIFNQAGIPTYRTPESAVVAFMHLVEYRRNQKQLMETPTTAEA 468

Query: 511 VAVINIGLRSFALELQSA 528
           V V  +   S    +   
Sbjct: 469 VHVSEVN--SAKQWINEH 484


>UniRef50_A8MDR5 CoA-binding domain protein n=7 Tax=Thermoprotei RepID=A8MDR5_CALMQ
          Length = 477

 Score =  223 bits (567), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 64/469 (13%), Positives = 141/469 (30%), Gaps = 68/469 (14%)

Query: 66  VAIRSEAADAGIAQAIM--QQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALI 123
           VA+       G    ++    L +   ++   +    ++   + + S  +   + +LA+I
Sbjct: 24  VAVIGATPKPGHVGYVIMSNLLSKFKGKVILVNPRYDSINGAKCYKSITEVNDEVDLAVI 83

Query: 124 SVAGEYAAELANQALDRNLNV-MMFSDNVTL------EDEIQLKTRAREKGLLVMGPDCG 176
           +V      ++  +A+ +N+   ++ S   +         E +++   +   + V+GP+C 
Sbjct: 84  AVPAPVVPQVTAEAVKKNVKALIIISGGFSEVGDEGRRLEDEVREIVKNTQVRVLGPNCI 143

Query: 177 TSMIAGTPLAF-------ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
               A   L             P+G I +I  SG     +    +    GI  A+  G +
Sbjct: 144 GVYNADNGLDTFFLPEDRMGRPPKGPIALISQSGAVAAAILDWASRRRLGIGLAVNYGNK 203

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKP---PAEAVRLKIVNAMKATGKPTVALF 286
                   ++    LE L+ +   +V+    +    P E +R           KP +   
Sbjct: 204 L------DVNESELLEYLANNSNVKVITIYMEGLKYPGEGLRFLETAKKVTQIKPVIVYK 257

Query: 287 LGYTPAVARDENVWFASSLDEAARLACLLSRVTARRN---------------AIAPVSSG 331
            G T A A       A+   +         +                        P    
Sbjct: 258 AGRTKASAGAVASHTAALAGDYEIYRGAFRQAGLIEANSVREMFDLAKALATQPLPRGRR 317

Query: 332 FICGLYTG--GTLAAEAAGLLAGHLGVEADDT---HQHGMMLDADSHQIIDLGDDFYTVG 386
            +    +G  G  A +   +L   +    +      +  +   A     +D+        
Sbjct: 318 VLVLTDSGGMGIQAVDTLSMLGLEVPELPETIQSMLRKFLPPLAIVRNPVDVTGSATD-- 375

Query: 387 RPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIG-FGATADPAASLVSAWQKACAARLDN 445
                        ++  +     V + L+  ++   G T +    ++ A           
Sbjct: 376 --------EYYKIVLDSILPTSYVDMALIVALMQIPGLTPNLVNYIIDA---------KR 418

Query: 446 QPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH 494
                +    G     +  ++    LED GI V ++         AL+ 
Sbjct: 419 YGKPMVVVSFGGSAMMEKFNEA---LEDNGIPVYATPDRGARALWALVQ 464


>UniRef50_Q2LS75 Acetyl-CoA synthetase beta subunit n=1 Tax=Syntrophus
           aciditrophicus SB RepID=Q2LS75_SYNAS
          Length = 697

 Score =  222 bits (566), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 70/452 (15%), Positives = 136/452 (30%), Gaps = 60/452 (13%)

Query: 87  EALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNL-NVM 145
               ++   +  +  +  +R + S  +     NL +IS+  +       + +   +  VM
Sbjct: 34  GYQGRIYPINPKADEICGLRAFPSITEVPETVNLVIISMGRDQVVAAFKECIQSGVKRVM 93

Query: 146 MFSDNVTLED------EIQLKTRAREKGLLVMGPDCGTSMIA--GTPLAFANVMPE---G 194
           + S      D      + ++   ARE G+ V+GP+    +        +F +++      
Sbjct: 94  IVSQGFADADPHGEKLQNEIVRLARESGIRVVGPNTLGILNNFRNFSTSFVDLIKPKKIP 153

Query: 195 NIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSE 254
            + +I  +G  IQ     +A    G    IG            +  + ALE   AD ++ 
Sbjct: 154 PVSLIAQTG-MIQVASHNLAYHDWGKALDIG--------NACDVDFVDALEYFGADPETR 204

Query: 255 VLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACL 314
           V+    +            +  +  KP +    G T A A+      AS   E       
Sbjct: 205 VIVVHMEGIIRGREFLKAASRISPDKPIIIFKTGRTTAGAKAALSHTASLTGEDEIAEAA 264

Query: 315 LSRVTARRNAIAPVSSGFICG-----------------LYTGGTLAAEA----AGLLAGH 353
            +R    R          I                      GG +A +A       +A  
Sbjct: 265 FNRAGLIRVKNGSELKDAIRSFIQFEDMEGPRLGVLTPTGAGGIMATDACEDFGLKIAEL 324

Query: 354 LGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVL 413
                D   +         + I     D + VG          R   + +L   P+V  +
Sbjct: 325 PEGLPDKLKKGIPDWVHIGNPI-----DIWPVGMLGGGYSQAYR-TALMELLKSPKVDGV 378

Query: 414 LLDVVIGFGATADPAASLVSAWQKACAARLDN---QPLYAIATVTGTERDPQCRSQQIAT 470
           L   V    +   P    +   +   AAR ++   +P+      +GT+   +        
Sbjct: 379 LGVTV----SVDSPLHKNIDIVEAVAAARRESGSRKPIAMWVYGSGTDDTVERLEPAT-- 432

Query: 471 LEDAGIAVVSSLPEATLLAAALIHPLSPAAQQ 502
                +A   S+  A    +          ++
Sbjct: 433 ---DNVACFESVERAAQGLSFCYRYHQLRKRE 461


>UniRef50_A5V1W2 CoA-binding domain protein n=7 Tax=Bacteria RepID=A5V1W2_ROSS1
          Length = 698

 Score =  222 bits (566), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 70/474 (14%), Positives = 133/474 (28%), Gaps = 58/474 (12%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQLAQGSGSSQA--LTQVRRWDSACQKLPDANLAL 122
           VA+   + D       I++ + +A           +A  +  +  + S  Q     +LA+
Sbjct: 11  VAVVGASPDPAKLGHRILKNILDAGYSGRIFPIHPRATQILNLPAYPSVEQVPEPIDLAV 70

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLE------DEIQLKTRAREKGLLVMGPDC 175
           + V      E+A     R +  +++ S             E +L    R   + ++GP+C
Sbjct: 71  VVVPAAVTLEVAEACGKRGVRGLVVISAGFKEIGPEGRVLEERLLEITRRYNMRMIGPNC 130

Query: 176 GTSMIAGTPLA--FANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
              +   T L   FA + P  G I  +  SG     +     + G G +  + LG +   
Sbjct: 131 LGVIDTTTRLNASFAALYPHAGQIAFMSQSGALCTAILDWSRVQGIGFSRFVSLGNK--- 187

Query: 233 REVGGISALTALEMLSADE-KSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
                +  +T L+    D+  + V+    +          V        P +A+  G T 
Sbjct: 188 ---ADVDEVTLLQAWGCDKVHNRVILAYLEGIGNGDEFVAVARQVTKHIPVIAIKSGATQ 244

Query: 292 AVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLA 351
           A AR  +    +             +    R          +  L+      A    +  
Sbjct: 245 AGARAASSHTGALAGAEHAYEAAFDQCGVLRAR-------SMQELFDFALAFAYQPLIPG 297

Query: 352 GHLGVEADDTHQHGMMLDADSHQIIDLG--------------DDFYTVGRPHPMID---P 394
             L +  +      +  DA  H  + L                   +V  P  +I     
Sbjct: 298 DRLAIVTNAGGPGIIATDAAVHCGLRLAELAPATIAALRAALPSAASVYNPIDIIGDARA 357

Query: 395 TLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATV 454
                 +      P V  +L+      G+             +         P     + 
Sbjct: 358 DRYRVALRAALDDPNVDAVLVLFTPQAGSEP-------EETARVIVELSAGSPKPVATSF 410

Query: 455 TGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLL 508
            G         + + TL D  I        A     A++   +       P   
Sbjct: 411 MGAA----SIGEALRTLNDHKIPNYPFPERAVAALGAMV---AQRRWVDRPPGE 457


>UniRef50_A4EUN0 Predicted Acetyl-CoA synthetase n=2 Tax=Proteobacteria
           RepID=A4EUN0_9RHOB
          Length = 714

 Score =  222 bits (565), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 79/520 (15%), Positives = 158/520 (30%), Gaps = 63/520 (12%)

Query: 62  NDICVAIRSEAADAGI-AQAIMQQLEEALKQLAQGSGSSQ--ALTQVRRWDSACQKLPDA 118
           N   +AI   + D        +++L       A    + +   +  ++ + S  +     
Sbjct: 10  NAASIAIIGASNDPAKRGNQAIRKLRADGYAGAIYPINPKAPEVLGLKAYPSVLEVEGSI 69

Query: 119 NLALISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRARE--KGLLVM 171
           ++ L+    +    +  Q  ++ +   +     FS+     + I   T A      + ++
Sbjct: 70  DVVLVCTPAKTLPAILAQCGEKGIPGAVVLAAGFSETGPEGEAIAEATLAAAKAHNVRLV 129

Query: 172 GPDCGTSMIAGTPLAFANV--MPEGNIGVIGASGTGIQELCSQIALAG-EGITHAIGLGG 228
           GP+          +    V  +  GNIG+   SG  +    ++    G  G +  +G+G 
Sbjct: 130 GPNTNGVFNLHNNMNMVGVQDVEPGNIGICSQSGNMMLAFVTEAKRRGGVGFSSYVGVGN 189

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG 288
           +        ++    L+  + D  ++   F  +   +              KP +    G
Sbjct: 190 QL------DVTLSEYLQYFADDADTKAPVFYVEGFRDGRAFLDTCREVTQRKPVIIYKSG 243

Query: 289 YTPAVARDENVWFASSLDEAARLACLLSRVTARRN--------------AIAPVSSGFIC 334
            T A     +    S     A    LL +  A                  +     G + 
Sbjct: 244 RTEAGQVAASSHTGSLASSFALTRGLLKQAGATVVEQSDKILSIAEGLSKLPVPMGGKVA 303

Query: 335 GLYTGG---TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPM 391
            L  GG   T+  +A       L   +  T +    +   +   ++  D           
Sbjct: 304 ILADGGGHATVTVDALVDAGVELASLSPATIEKLRSILPAAASCVNPVDVAGGTDD---- 359

Query: 392 IDPTLRNQLIADLGAKPQVRVL-LLDVVIGFGATADPA-ASLVSAWQKACAARLDNQPLY 449
            +P +       + A   V +L ++ +  GF A  +PA   + +   +  AA  ++    
Sbjct: 360 -NPLISAACAEAILADQNVDILMVIGMYGGFAARFNPALLEVETETSQRMAALAEHHGKP 418

Query: 450 AIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH----PLSPAAQQHTP 505
            I            R++ I  L+DAG+ V      A    + LI         AA     
Sbjct: 419 LIVQSVYNAL----RTRPIEALKDAGVPVFVWPEPAVRCVSELIGYAQARRRNAASPLVR 474

Query: 506 SLLENV-------AVINIGLRSFA-----LELQSASKPVV 533
                         V+N G  +F        L +    V 
Sbjct: 475 PDEPAPSGTALVDRVVNTGRDAFYEYEAKDLLATYGIKVP 514


>UniRef50_A0LS83 CoA-binding domain protein n=1 Tax=Acidothermus cellulolyticus 11B
           RepID=A0LS83_ACIC1
          Length = 911

 Score =  222 bits (565), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 80/510 (15%), Positives = 156/510 (30%), Gaps = 68/510 (13%)

Query: 20  ISRKLSESENVDDVSVMMGTP----ANKALLDTTGFWHDDFNNATPNDICVAIRSEAADA 75
           + RK    E V    + +       A     +            +P    VA+    A+ 
Sbjct: 165 LPRKARSLEGVVHFEIPLTMDETYRAAVDRREAAANARSLARVLSP--KVVAVVGAGANP 222

Query: 76  -GIAQAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAE 132
            G+   I+  + +   +      + S   +  V  + S        ++ +++V       
Sbjct: 223 QGLGHQILVNIVQGGYRGEVFAINRSGHRVAGVPAYASLADLPASPDVVIVAVPAAEVLA 282

Query: 133 LANQALDRN-LNVMMFSDNVTL------EDEIQLKTRAREKGLLVMGPDCGTSMIAGTPL 185
           +A QA  R+   +++ S           E + +L    R  G+ ++GP+C         +
Sbjct: 283 VARQAAQRHPAGLVVISAGFAEAGAEGAERQRELLAICRAAGMRLIGPNCMGIANIDPEI 342

Query: 186 AF-----ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
           +      A + P G I ++  SG       +  A +G G+   I  G +        +S 
Sbjct: 343 SLNATFCATMPPPGGISLMSQSGAVGIAALNHAARSGVGLATFISAGNK------ADVSG 396

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVW 300
              L    +D ++ V A   +      +   +       KP VA+  G T A  R     
Sbjct: 397 NDVLCAWESDPRTRVCALYLESFGNPRKFARIARRVGKAKPIVAVKAGRTLAGIRGAASH 456

Query: 301 FASSLDEAARLACLLSRVTARR---------------NAIAPVSSGFICGLYTGGT---- 341
            A++      +  L ++    R                A  P          +GG     
Sbjct: 457 TAAAATPDVVVDSLFAQAGVTRVDSLEDLFNVATFFDVAPLPAGRRVAIVGNSGGPGVLA 516

Query: 342 -LAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQL 400
             A EAAGL    LG       +  +   A     +D+     T           +    
Sbjct: 517 ADACEAAGLEVIQLGERTRTLLRSLLPEGAAVDNPVDVVASTETR----------VFEAA 566

Query: 401 IADLGAKPQVRVLLLDV-VIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTER 459
           +  +   P+V  +++    I  G+  + A ++    ++             +A + G   
Sbjct: 567 LRIVAHDPEVDAVVVVFTEIRPGSIPETAKAIAKVSREYSG-------KPFVACLLGHPG 619

Query: 460 DPQCRSQQIATLEDAGIAVVSSLPEATLLA 489
            P   +     L    + V +    A    
Sbjct: 620 IPDELTDGSGRLL---VPVYAFPEPAVRAL 646


>UniRef50_B9R2H8 Acetyltransferase, GNAT family n=1 Tax=Labrenzia alexandrii DFL-11
           RepID=B9R2H8_9RHOB
          Length = 910

 Score =  222 bits (565), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 62/464 (13%), Positives = 122/464 (26%), Gaps = 45/464 (9%)

Query: 66  VAIRSEAADAGIAQAIM---QQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+       G+    +    Q  E   +++                S  +     +L +
Sbjct: 15  IAVLGPCRHPGVLTDKLIDCLQAIETQHKVSLVGIDYSVPFNGTSVSSLAELKHAPDLVI 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMFS----DNVTLEDEIQLKTRAREKGLLVMGPDCGTS 178
                E    +  +  DR    ++      +          +  AR+  L ++GP     
Sbjct: 75  YLAKAEKLPRVIEELGDRGTRAVLIPSPGYEYWPEPIMQACREAARKTTLRLIGPGSLGI 134

Query: 179 MIAGTPLAF---ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREV 235
            +    L     A V  +G+I     SG  +    S       G +  + LG R      
Sbjct: 135 SVPAKGLNALLSAEVPGKGDIAFFSRSGAVLNATLSWAKTHNTGFSSIVSLGAR------ 188

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVAR 295
             +     ++  + D ++  +    +  A   +        A GKP + L  G +     
Sbjct: 189 IDVDVSDLIDYFAQDYRTRAIVLHLEGVAVPHKFMSAARAAARGKPVIVLRSGRSRDTGG 248

Query: 296 DENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLY-----------------T 338
                                R    R          +  L                  +
Sbjct: 249 TGRTHAGRLAKSDLVYETAFRRAGLLRVYDLDEMFEALETLSHVRVPQCRNLAVIANGRS 308

Query: 339 GGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRN 398
              LA +    L       + +T +H       S+ + D      ++          L  
Sbjct: 309 LANLAYDRLDALGAQFASLSPETLEHLQQFLGPSNDLDDTSAAQASIILREATAAEDL-T 367

Query: 399 QLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKAC--AARLDNQPLYAIATVTG 456
           + I  +     V   +   V+   +   P   L  A  +A     +   +    +A + G
Sbjct: 368 ETITTVLKDRNVDGAV---VLQAASAFQPLPVLAKAVAEAATLDRKRPGRRKALVAGLIG 424

Query: 457 TERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
            +      S     L +A +   +S  EA      L H      
Sbjct: 425 GD------SATREVLTEAKVPNYASPAEAARSLMHLAHDAQARE 462


>UniRef50_B6R8H6 N-acetyltransferase n=1 Tax=Pseudovibrio sp. JE062
           RepID=B6R8H6_9RHOB
          Length = 905

 Score =  221 bits (563), Expect = 5e-56,   Method: Composition-based stats.
 Identities = 72/488 (14%), Positives = 145/488 (29%), Gaps = 48/488 (9%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQLAQGSGSSQ--ALTQVRRWDSACQKLPDANLAL 122
           +AI    +   +  Q ++  +E +     +        +    +   S  +    A+LA+
Sbjct: 15  IAIVGPNSKQEVILQRLIDSIESSGFSGPKTFVGLPDASADGFKGVASIAEVESKADLAI 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMF--SDNVTLEDEI--QLKTRAREKGLLVMGPDCGTS 178
           +      AAE   Q  ++    ++   S   +  DE    L   A    + ++GP     
Sbjct: 75  LLGDHTTAAEDIKQLGEQGTRAVVIPASGFDSWRDEHLDALLKAAHPFNIRILGPGSLGI 134

Query: 179 MIAGTPLAF---ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREV 235
               + L+    +    +G + +I  SGT      +       G +  + LG R      
Sbjct: 135 ASPHSKLSTLLTSEQALKGELALISRSGTIFNTTLAWAKANSIGFSGVVSLGRRL----- 189

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVAR 295
             +     L+  + D +++ +    +  A   +        A  KP + +  G +     
Sbjct: 190 -DVDVSDLLDWYAQDYRTKAILVHLETIANPRKFMSAARAAARSKPVIVIRSGASRDQHI 248

Query: 296 DENVWFASSLDEAARLACLLSRVTARRN--------------AIAPVSSGFICGLYTGGT 341
                 +      +     L R    R                +AP +   +  +  G +
Sbjct: 249 SGTAHSSRLATRDSVYDAALQRAGVLRVYDLDEMFEAAETITRVAPSAGRRLSIIANGRS 308

Query: 342 LAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLI 401
           LA  AA  LA   G  A  + +    L + +       +             P    + I
Sbjct: 309 LATLAADRLAKVGGKLAPISEETKEKLVSLTRTDARADNPMVLQ----EAASPEEFKEGI 364

Query: 402 ADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLD--NQPLYAIATVTGTER 459
           + L   P    +L   +    A  D    +  A  +A         +    + T+ G   
Sbjct: 365 SALLKDPNSDGVL--AIAAPTAFEDFT-EIAKALAEAGKEDRKRLGKHQAFVTTLAGGAN 421

Query: 460 DPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPS-LLENVAVINIGL 518
            P         L++A +    S   A      L+      A+ H  +      +     L
Sbjct: 422 IP------RQVLDEARVPCYPSPSGAIRSFMHLVRYKE--AKDHLSAVPDSLPSDYKPNL 473

Query: 519 RSFALELQ 526
           R     ++
Sbjct: 474 RLAKETIR 481


>UniRef50_C4ZN05 CoA-binding domain protein n=1 Tax=Thauera sp. MZ1T
           RepID=C4ZN05_THASP
          Length = 728

 Score =  220 bits (561), Expect = 9e-56,   Method: Composition-based stats.
 Identities = 83/493 (16%), Positives = 141/493 (28%), Gaps = 43/493 (8%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQ--ALTQVRRWDSACQKLPDANLAL 122
           +AI   +AD        M  L +   +      + +   +  V    +        +LAL
Sbjct: 27  IAIVGASADPTKRGYKAMVGLVKGDYRGRVYPINPKVPEILGVPTCATLDDVPGPIDLAL 86

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDC 175
           I    +    L      + +   +        S       E Q+   AR  G+ ++GP+ 
Sbjct: 87  ICTPAKTLPGLLEACGRKGVKGAVILASGFRESGPEGARLEQQVLDAARAGGVRIIGPNT 146

Query: 176 GTSMIAGTPLAFANV--MPEGNIGVIGASGTGIQELCSQIALAG-EGITHAIGLGGRDLS 232
                    +   ++     G+IG I  SG  +  L  +    G  G +  +G G +   
Sbjct: 147 SGMFNLHHKVNLLDLRNARPGDIGFISQSGNMLLALVLEAEHNGHVGFSTYVGPGNQT-- 204

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                +     L  L  D  + V     +   +  R   V       KP V    G T  
Sbjct: 205 ----DVGFNDYLRYLGEDVHTRVATLYVEGFRDGQRFLEVAREITPVKPVVVYKSGATEL 260

Query: 293 VARDENVWFASSLDEAARLACLLSRVTA----RRNAIAPV----------SSGFICGLYT 338
             +  +    +     A    LL +V        + I PV              I  +  
Sbjct: 261 GKKAASSHTGALAGSYAMTVDLLRQVGVSVVHHSDEILPVAEGLALMQQARGRRIAVIAD 320

Query: 339 GGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRN 398
           GG  A   +  L+      A+ +      L A       L +     G      DP +  
Sbjct: 321 GGGQATITSDRLSESGLELAELSAATRKRLAAILFPQAALANPVDVAGS--SDADPEVLA 378

Query: 399 QLIADLGAKPQVRVLLLDVVIGFGATADPAASLVS---AWQKACAARLDNQPLYAIATVT 455
           + +  +     V  + L  + G G     A SL+       +A            +    
Sbjct: 379 RCVEIVADDDNVDAVFLVGMFG-GYHIRFAESLLGGEMRAAEAMIELARASAKPLVVYSL 437

Query: 456 GTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVIN 515
                P         L +AG+ V +S+ +A  +  AL         +H   L    A   
Sbjct: 438 YAPVKPPAL----RRLHEAGLPVYASIEQAVKVLEALAERGLYLQDRHGQPLQAGAAPDE 493

Query: 516 IGLRSFALELQSA 528
                FA      
Sbjct: 494 AMQAMFARAQNEG 506


>UniRef50_B0UM89 CoA-binding domain protein n=19 Tax=Bacteria RepID=B0UM89_METS4
          Length = 722

 Score =  220 bits (560), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 65/440 (14%), Positives = 130/440 (29%), Gaps = 33/440 (7%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGS--GSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +A+ G    ++M+ L     +         +  +  ++ + S        ++A+
Sbjct: 276 VAVIGASAEEGKIGNSVMKNLINGGYKGKIYPIHPKADTVLGLKAYRSVKDVPGPVDVAV 335

Query: 123 ISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
            ++  ++ A    +  ++ +   +     F++      + +L+   R   + +MGP+   
Sbjct: 336 FAIPAQFVAAALTECGEKGVAGAVLIPSGFAETGNEAGQRELQEIGRRYNIRLMGPNIYG 395

Query: 178 SMIAGTPLAFANVMP---EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSRE 234
                  L      P   +G   +   SG     +         G++  +GLG +     
Sbjct: 396 FYYMAKSLCATFCTPFDVQGQAALSSQSGGIGMAIIGFSRSTKMGVSAIVGLGNK----- 450

Query: 235 VGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVA 294
              I     L     D+ + V+A   +   +           +  KP + L  G T A A
Sbjct: 451 -SDIDEDDLLTFFEQDDSTRVIAQHCEDLKDGRSFAEAARRVSKKKPVIVLKAGRTSAGA 509

Query: 295 RDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHL 354
           R  +    +          +  +    R         F  G+    T   E   ++ G  
Sbjct: 510 RAASSHTGALAGNDKIYEDVFKQCGVIRARSLRQLLEFARGVPVLPTPKGENVVIITGAG 569

Query: 355 G-------VEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID---PTLRNQLIADL 404
           G          D+      M D            F   G P  +     P      I   
Sbjct: 570 GSGVLLSDAVVDNGLSLMAMPDDLDAAFRKFIPPFGAAGNPVDITGGEPPVTYQNTIRLG 629

Query: 405 GAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCR 464
               ++  L+L           P     +  +     R        +A++ G   D Q  
Sbjct: 630 LEDERIHALILGY--WHTIITPPMVFARNVVEVRDEMRARGIEKPIVASLAG---DVQ-V 683

Query: 465 SQQIATLEDAGIAVVSSLPE 484
            +    L D GI   +   E
Sbjct: 684 EEASQYLYDHGIPAYAYSTE 703


>UniRef50_A2SEI4 Acyl-CoA synthetase (ADP forming) n=13 Tax=Burkholderiales
           RepID=A2SEI4_METPP
          Length = 918

 Score =  220 bits (559), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 79/478 (16%), Positives = 137/478 (28%), Gaps = 48/478 (10%)

Query: 57  NNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLP 116
              +P  I + +     D        + L +AL+     +G+ Q L        A     
Sbjct: 30  PLFSPESI-IVLAGAPDDPTGQTPQARVLHQALRAQP-YAGALQFLDIHATGTLAELAQT 87

Query: 117 DANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQLKTRAREKGLLVMGPDC 175
            A+LA+I++  +  A     A        ++ S  +  E    LK  A+ +G+ ++GP+ 
Sbjct: 88  RADLAVIALPPQQVASALEVAGRLACRSALVVSSGIGAEAAATLKKIAQREGIHLLGPNG 147

Query: 176 GTSMIAGTPLAFANV---MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
                    L  +        G++ ++  SG     +    +    G +  + LG     
Sbjct: 148 LGFQRPALQLNASAAGPLAKPGSLALVSQSGALTTSVLDWASTNAVGFSSVVSLG----- 202

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                +     L+ L+ D ++  +    +  + A          A  KP V L  G  PA
Sbjct: 203 -PNTSVDIAQVLDYLANDAQTHSIVVYVEGISSARHFMSALRSAAKAKPVVVLKAGRKPA 261

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRNAIAP--------------VSSGFICGLYT 338
                     + +         L R  A R                        +  +  
Sbjct: 262 GNEAAQTHSGAIVGSDDVFDAALRRAGAVRVRSFVELFSAAKCLASRYRPVGRRLAIVTN 321

Query: 339 G---GTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPT 395
           G   G LAA+    L  HLG  + ++             + DL D     G       P 
Sbjct: 322 GGGPGVLAADWVNELYLHLGRLSAESAAALAPQLPPLASLSDLIDLSEDAG-------PE 374

Query: 396 LRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVT 455
                I   G   Q+  +L       G          +    A            ++   
Sbjct: 375 HYRAAIDAAGNDTQIDGVLTVYSPKVGVD-------AADIAGALVEVKHTMGKPLLSCWM 427

Query: 456 GTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH-PLSPAAQQHTPSLLENVA 512
           G              L +AGI    +   A      +     +    Q TPS L  +A
Sbjct: 428 GDA----SVGAARELLNEAGIPGFRTPEAAVGAFGNIASFYQNQLLLQQTPSPLSTLA 481


>UniRef50_Q2YZQ4 Acyl-CoA synthetase (NDP forming) n=1 Tax=uncultured delta
           proteobacterium RepID=Q2YZQ4_9DELT
          Length = 504

 Score =  220 bits (559), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 78/481 (16%), Positives = 146/481 (30%), Gaps = 53/481 (11%)

Query: 59  ATPNDICVAIRSEAADAGIAQAI-MQQLEEALKQLAQGSGS--SQALTQVRRWDSACQKL 115
             P  I VA  SE  +   A  + +Q L +   +      +     +  ++ + S     
Sbjct: 34  FRPRTIAVAGVSENTNKFNAGLMFLQGLMQFGFKGQIYPMNPLGGKIMGMKIYKSVKDIP 93

Query: 116 PDANLALISVAGEYAAELANQALDRNLNVMMF-SDNVTL-------EDEIQLKTRAREKG 167
              +  + ++   Y  +L   A  + +  + F +   +          +  +  RA+  G
Sbjct: 94  DKIDFVISAIPSRYTPQLMADAAQKGVKAIHFFTSGFSEIENVEGKHLQADIIARAKAGG 153

Query: 168 LLVMGPDCGTSMIAGTPLAFANVMPE--GNIGVIGASGTGIQELCSQIALAGEGITHAIG 225
           + V+GP+C         L+F     +  G + +I  SG        +    G   +  I 
Sbjct: 154 IRVVGPNCLGLYCPSGGLSFNADFDKTSGPVAMISQSGGNAAHCVQEGNDRGVLFSKVIS 213

Query: 226 LGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVAL 285
           +G          ++    LE L+ DE+++++    +   E  R           KP + L
Sbjct: 214 MGNG------ADLNESDYLEYLTHDEETKIITAYIEGVREGPRFLRALKSATKSKPVIIL 267

Query: 286 FLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIA--------------PVSSG 331
            +G + + A       A+           L +    R +                     
Sbjct: 268 KVGTSVSGAEAAVSHTAAMAGSNQVWEGALRQAGVIRTSSIEEMIDITIAFQHMPAPKGN 327

Query: 332 FICGLYTGG----TLAAE--AAGLLAGHLGVEADDTHQHGMMLDADS--HQIIDLGD--D 381
            I  +  GG     LA E   AGL    LG E   +       +A       +DL +   
Sbjct: 328 KIVVVGIGGGASVILADEFTNAGLSLPRLGDELRKSLIELHPSEAGRIFKNPVDLNNFES 387

Query: 382 FYTVGRPHPMIDPTLRNQLIADLGAKPQVRVL-LLDVVIGFGATADPAASLVSAWQKACA 440
             T  +    +D      L+A   A     ++ + D  +  G        +    +    
Sbjct: 388 SETFFKTMKALDQCEEANLLAIHIAFDHFGLISIKDKELMIGVYLKLVGEIKKEIK---- 443

Query: 441 ARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
                +PL  I     + +           L  AG AV  S+  A +     I       
Sbjct: 444 -----KPLAIILHSYASTQMRNLAYDAAKELTAAGFAVFPSIQRAAMALTKFISYHEERR 498

Query: 501 Q 501
            
Sbjct: 499 T 499


>UniRef50_D2EE92 CoA-binding domain protein n=2 Tax=Candidatus Parvarchaeum
           acidiphilum ARMAN-4 RepID=D2EE92_9EURY
          Length = 683

 Score =  218 bits (556), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 58/476 (12%), Positives = 133/476 (27%), Gaps = 63/476 (13%)

Query: 59  ATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSS--QALTQVRRWDSACQKLP 116
             P+   +A+   + D     + + +             +     L  ++ + S      
Sbjct: 7   FEPDS--IAVIGASRDPNKVGSAVLKNLIITFHGKIFPINPFVDELQGLKAYKSVLSVKE 64

Query: 117 DANLALISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLL 169
             ++A+I++  +       +     + + +              + E +++    +  + 
Sbjct: 65  KIDVAIIAIPAQMVLSTLKECEKAKIPLAVILSAGFNEIGGEGAKREEEIRKFLSKAKIR 124

Query: 170 VMGPDCGTSMIAGTP-----LAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           ++GP+C   +          L   + + +GN G I  SG  +  +    +    G +  I
Sbjct: 125 IIGPNCLGIINTDPSFNATFLDPNSRVIKGNAGFISQSGALLSAVVDDASTNNIGFSKII 184

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
            +G          IS    +E    DEK++VLA   +               +  KP + 
Sbjct: 185 SIGN------ATDISEADIIESFKTDEKTKVLALYLEGLNNGKDFLKAGMSFSQEKPLLI 238

Query: 285 LFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFIC---------- 334
           L  G   + +   +    S   +        +R+ A           F+           
Sbjct: 239 LKGGKFKSTSTAVSSHTGSMAGDYKAYELAFNRIGAISVENIDDLFNFMRDAPNIKINSD 298

Query: 335 ----GLYTG--GTLAAEAAGLLAGHLGVEAD---DTHQHGMMLDADSHQIIDLGDDFYTV 385
                   G  G +  +        L    D   +     +  +A+ H  +D+  D    
Sbjct: 299 EVIIATNAGGAGVVTTDHIINSGLKLAKFNDKLLNELSKVLPKEANIHNPVDMVGDAT-- 356

Query: 386 GRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDN 445
                   P      +  L  + +  ++L          + P         +        
Sbjct: 357 --------PERYRDTLELLVQQNKPIIILF----SPQEMSQPL-ETAKQIYETHLRHPS- 402

Query: 446 QPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQ 501
             +  ++   G         +    L +  + +     EA  +   L    S  AQ
Sbjct: 403 --VPFLSVFLGGA----RVDKARRFLLERNMPIYEYPNEAVFMVKGLFTYYSHRAQ 452


>UniRef50_A8ZSN5 CoA-binding domain protein n=3 Tax=Desulfobacteraceae
           RepID=A8ZSN5_DESOH
          Length = 492

 Score =  218 bits (554), Expect = 6e-55,   Method: Composition-based stats.
 Identities = 66/482 (13%), Positives = 141/482 (29%), Gaps = 49/482 (10%)

Query: 66  VAIRSEAADAGIAQAIMQQLE---EALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VAI   + +      I+ +     +   ++       + +  +  +DS        +LA+
Sbjct: 19  VAIFGASNNHSSMGTIILRAMMAFDFPGKIYPVHLKEKEVQGLTAFDSVESLPEAPDLAV 78

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNV------TLEDEIQLKTRAREKGLLVMGPDC 175
           I +      E       + +   ++ S           E E +L   A + G+ ++GP+C
Sbjct: 79  IVLPTRIVCETMEACGKKGIRNAIVVSGGFKEVGPEGAEREKELAAIAGKYGISIIGPNC 138

Query: 176 GTSMIAGTPLAFAN---VMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
                A   L           G IG++  SG+ + ++ + +     G + A  +G     
Sbjct: 139 LGVTNAHARLNTTPHRYYGKPGFIGLVSQSGSFVTQMFAYLDQLHLGFSTAFSIGNE--- 195

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                   +  LE L A   ++V+A   +      +           KP VAL++G +  
Sbjct: 196 ---VNTDLVDCLEFLGACPDTKVIALYVEAIRRGRKFVETARKIVPHKPIVALYVGGSET 252

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRNA---------------IAPVSSGFICGLY 337
             +       S        + +  +    R +                 P ++      +
Sbjct: 253 GRKAALSHTGSMSGPDDLYSGIFRQSGVIRVSSITELFDCCMAFGHLPQPAANRVFIQTH 312

Query: 338 TGGT--LAAEAAGLLAGHLGVEADDTHQHGMMLDADS---HQIIDLGDDFYTVGRPHPMI 392
           +GG   +AA+A G     L   +  T +    L   +      IDL            + 
Sbjct: 313 SGGPGAVAADACGRSGLVLPEPSAKTAEKLKALVPATGSVKNPIDLTFTKDMTQFFADIP 372

Query: 393 -----DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQP 447
                DP     +         ++ +LL + +           +           +    
Sbjct: 373 GVLLEDPGCDALMFYYYTPADMIKRVLLQMGVPAAELDAKMDEVSQHISAQMQGLIKRSG 432

Query: 448 LYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSL 507
                               + +L   G+        A    AA++   +   +    S 
Sbjct: 433 KPVFCFSYQG-----RSETAVQSLSALGVPFYQGPERAVRALAAMVAYGTLKEKIVRQSG 487

Query: 508 LE 509
           ++
Sbjct: 488 ID 489


>UniRef50_Q2LVF9 Acetyl-CoA synthetase beta subunit n=1 Tax=Syntrophus
           aciditrophicus SB RepID=Q2LVF9_SYNAS
          Length = 701

 Score =  218 bits (554), Expect = 6e-55,   Method: Composition-based stats.
 Identities = 70/532 (13%), Positives = 132/532 (24%), Gaps = 79/532 (14%)

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGS--SQALTQVRRWDSACQKLPDAN 119
           N   +A+             + +  +   +      +     +  +  + S        +
Sbjct: 6   NPQSIAVIGATPKTFKGGYAILKNLKTTFKGRIYPINPQYAEIEGLPCFPSIKDIPEAVD 65

Query: 120 LALISVAGEYAAELANQALDRNLNVMMF-SDNVTLEDEI------QLKTRAREKGLLVMG 172
           LA+I +A  +      Q   + ++ +M  S      DE        +++     G+ V G
Sbjct: 66  LAIIFIAAVHVPAALEQCAIKGVSGIMIESGGFAEADEKGKSLQDAIRSFVERTGIRVWG 125

Query: 173 PDCGTSMIAGTPLAFANVMP--------EGNIGVIGASGTGIQELCSQIALAGE-GITHA 223
           P+C   +       F+   P         G + +I  SG         I   G  G +  
Sbjct: 126 PNCMGLVDGIRGHIFSFTDPKVLPFCLHPGPVSLIVQSGMLSAGFVIDILSHGITGFSKV 185

Query: 224 IGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTV 283
             +G +        I     L  L  D  +  +    +      R   +   + + KP +
Sbjct: 186 CSIGNK------ADIDESDVLSFLLEDPDTRCVGLYLESFVNGRRFMDL--CRKSDKPVI 237

Query: 284 ALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGL------- 336
            L  G +   A       AS        A  L++  A           F   L       
Sbjct: 238 VLKGGRSRKGAEAAVSHTASLAGNYRVAAGALAQAGAYEARDFHQLVDFCRTLALYPPKR 297

Query: 337 -----------YTGG-----TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGD 380
                      ++G      T       L    L                     +D+  
Sbjct: 298 NKSRGRIAVITFSGAAGIVSTDFMNELDLDVAELSEATKIRLGRIFPEWMPVANPVDIWP 357

Query: 381 DFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACA 440
                   H      + +  +      P V  +L+    G+          +       +
Sbjct: 358 AIE----QHSGTGLDIYSLAMEAALDDPGVDAVLVHAFSGYTR--------IRLDFDKIS 405

Query: 441 ARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
            +  +     +  + G   D      +     D G+ V   L  A    + L        
Sbjct: 406 RQSRSSGKPVLLWLPGNRDDAFQVQIKAR---DCGVLVFHELYRAVSCLSILFQRTGTCW 462

Query: 501 QQHTPSLLENVAVINI---------------GLRSFALELQSASKPVVHYQW 537
                  +    + NI                 R     L+S   P V   W
Sbjct: 463 LPEGNQPVPTDELQNIPDDISDLLNNAGGSLDERLSKNILKSFGIPTVEETW 514


>UniRef50_C4XLT1 CoA-binding domain protein n=1 Tax=Desulfovibrio magneticus RS-1
           RepID=C4XLT1_DESMR
          Length = 899

 Score =  218 bits (554), Expect = 7e-55,   Method: Composition-based stats.
 Identities = 73/472 (15%), Positives = 141/472 (29%), Gaps = 58/472 (12%)

Query: 59  ATPNDICVAIRSEAADAGIAQAIMQQ---LEEALKQLAQGSGSSQALTQVRRWDSACQKL 115
             PN   VA+   +AD     A++ +     + L  +   +     +  V  + S     
Sbjct: 10  FRPNS--VAVVGASADPAHVGAVVMRNLLGGKFLGPVMPVAPDLAEIDGVTCYRSVETLP 67

Query: 116 PDANLALISVAGEYAAELANQALDRNLNVMM--------FSDNVTLEDEIQLKTRAREKG 167
              +LA+I    E   E   +   R +   +               + + ++   A   G
Sbjct: 68  LTPDLAVICTGPESVPETLRELGRRGVGAAVALPPGYAKLEPAAKRDLQQRMIEAAAPSG 127

Query: 168 LLVMGPDCGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           + ++GP     ++ G  L  +        G +  I  S +    +       G G +H +
Sbjct: 128 IRILGPSGMGLLVPGIGLNCSLANRDARPGRMAFISQSASLFTAVLDWAHTKGVGFSHIL 187

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
            LG R        +     L+ +++D  +  +    +   +A      +   A  KP + 
Sbjct: 188 SLGDR------VDLKYADILDYMASDPNTRSILLYVESVTDARSFMSASRAAARNKPLLV 241

Query: 285 LFLGYTPAVARDENVWFA-SSLDEAARLACLLSRVTARR---------NAIAPVSSGFIC 334
           +  G                 + + A     + RV                 P+S   + 
Sbjct: 242 VKPGRKLWTLFPPGPDEGRDEVYDEAFRRAGMLRVGEIDTLFDAAETLARARPLSGDHLS 301

Query: 335 GLYTGGTLAAEAAGLLAGHLG------VEADDTHQHGMMLDADSHQIIDLGDDFYTVGRP 388
            L  GG++   AA  L    G       EAD      +  +     ++D+G D       
Sbjct: 302 ILTNGGSVGVMAADALLDGGGRLAPFDAEADAALSPLLGPNWSRKGVVDMGVDAA----- 356

Query: 389 HPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPL 448
                P+L    +  L   P    +L+  V   G + +  A        A A        
Sbjct: 357 -----PSLYADALRALLRIPGGSAVLVVHVPFPGVSPEATAK-------AVAEVAAKTSR 404

Query: 449 YAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
             +A   G +         +  L +AG+   ++  +A      L        
Sbjct: 405 TVLACFMGYDPAG---GDALKILNNAGVPAYATPDQAVSAFVQLARYRKNQE 453


>UniRef50_D0LBS1 CoA-binding domain protein n=2 Tax=Corynebacterineae
           RepID=D0LBS1_GORB4
          Length = 950

 Score =  217 bits (553), Expect = 8e-55,   Method: Composition-based stats.
 Identities = 74/480 (15%), Positives = 144/480 (30%), Gaps = 44/480 (9%)

Query: 46  LDTTGFWHDDFNNATPN---DICVAIRSEAADAGIAQAIMQQLEEALK---QLAQGSGSS 99
           +   GF    F    P    D    +  + AD G A+          +      +     
Sbjct: 241 IIAGGFTGPVFPVNGPGHGPDDAADVGDDPADHGTARPSAAGGASGSRGSVAGRRTRERP 300

Query: 100 QALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMF-------SDNVT 152
            ++  +R +++        +LA+++V  E   ++ +  L + +  ++        S    
Sbjct: 301 PSVRGIRAYETVRDIPDPVDLAVVAVPAERVPDVLDDCLVKAVRTLVVVSSGFADSGAQG 360

Query: 153 LEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPE-----GNIGVIGASGTGIQ 207
           L  E +L  + RE G+ ++GP+          +A    +       G +G    SG    
Sbjct: 361 LASEHRLVEQVREHGMRLVGPNALGVANNDPTVALNATLAPRIPAVGRVGFFCQSGALGI 420

Query: 208 ELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAV 267
            +    A    G++  +  G R        +S    L+    D  ++V+    +      
Sbjct: 421 AILDTAARRQIGLSTFVSAGNR------ADVSGNDLLQYWDTDTATDVVLLYLESFGNPR 474

Query: 268 RLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAP 327
           +   +    +  KP VA+  G             A+ LD+      +L +    +    P
Sbjct: 475 KFSRIARRVSRSKPIVAVKSGKGALTPVRAARSGAAGLDDQ-IARMVLEQAGVIQVDTIP 533

Query: 328 VSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGR 387
                   L+   T+ A         + +  + +    +  D      +D+ D       
Sbjct: 534 E-------LFDCATVFAFQPLPRGPRVRIIGNSSVLGSLAADTARSGGLDVLDTID---- 582

Query: 388 PHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQP 447
                        ++   A   V  +L+  V      AD       A   A      + P
Sbjct: 583 LGAGASEEQFESAVSAAMADTTVDAILVVFVPPVAVDAD---WHARALMAAANTPDADGP 639

Query: 448 LYAIATVTGTERDPQCRSQ-QIATLEDAG-IAVVSSLPEATLLAAALIHPLSPAAQQHTP 505
              + T    +  P    +     L D G I   +S       A AL      A  +  P
Sbjct: 640 KPIVTTFLAVDGIPPGLKKPGPGGLPDRGSIPSYASPE---RAATALARAWQYARWRLRP 696


>UniRef50_A1SKW5 CoA-binding domain protein n=3 Tax=Actinomycetales
           RepID=A1SKW5_NOCSJ
          Length = 899

 Score =  217 bits (553), Expect = 8e-55,   Method: Composition-based stats.
 Identities = 58/477 (12%), Positives = 150/477 (31%), Gaps = 41/477 (8%)

Query: 66  VAIRSEAADAGIAQAIMQQ---LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +         + +   + +   ++   + +S A++ +  + +      D ++A+
Sbjct: 206 VAVIGASRRQETIGQALVRNLVMGDFAGRVYAVNPTSSAVSGLPTYKTVGDIPDDVDVAI 265

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDE------IQLKTRAREKGLLVMGPDC 175
           ++V  E   ++      + ++ +++ S       E       +L   +R  GL ++GP+ 
Sbjct: 266 VAVPAEAVQDVVLDCAAKGVHGLVVISSGFAETGEEGRVRQRKLVGLSRSYGLRLIGPNA 325

Query: 176 GTSMIAGTPLAFAN-----VMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
              +     ++        + P G  G    SG     +  ++   G G++  +  G R 
Sbjct: 326 LGIINTAAEVSLNASLSPLMPPRGRAGFFCQSGALGTAILEKVYNRGLGLSTFVSAGNR- 384

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
                  +S    L+    D+ +EV+    +      +   +    +  KP +A+  G T
Sbjct: 385 -----ADVSGNDLLQYWEEDDSTEVVLLYLESIGNPRKFSRIARRVSLRKPIIAVRSGRT 439

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLL 350
                         +   A +  +  +    +          +  ++    L A      
Sbjct: 440 TQGV-PMGHAVRKIVAPPAAVDAMFRQAGVIQV-------DTLEEMFDVAQLLAHQPLPR 491

Query: 351 AGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQV 410
              + +  +      +  DA +   + +                      +      P++
Sbjct: 492 GRRVAIVGNSDALGLLAADAAAAVGLVVNKATA----LGAEASAEDFEDALDAAIDDPEI 547

Query: 411 RVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIAT 470
             ++   V     + +  A++++A  +             +++  G+E  P+        
Sbjct: 548 DSVVAVYVPPINVSGEDVANVLAAVGEQSD-------KPLVSSFLGSEGVPELLRVPDVA 600

Query: 471 LEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQS 527
              AG   V S P       AL   +  A    TP     +   ++ L +    +  
Sbjct: 601 GSTAGRGSVPSYPGVEAAVRALARVVEYAVWLRTPDG-ALLDPADVDLTAAKRLVNQ 656


>UniRef50_C8WUT7 CoA-binding domain protein n=2 Tax=Alicyclobacillus acidocaldarius
           RepID=C8WUT7_ALIAD
          Length = 637

 Score =  216 bits (551), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 66/460 (14%), Positives = 140/460 (30%), Gaps = 40/460 (8%)

Query: 65  CVAIRSEAADAGIAQAIMQQ---LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
            VA+   + +      ++ +     +    +   + S+Q++  VR + S        +LA
Sbjct: 12  VVAVVGASRNKDRLGHVLFRHILNSDFRGTVYPVNPSAQSVAAVRAYPSLRDVPEPVDLA 71

Query: 122 LISVAGEYAAELANQALDRNLN-VMMFSDNVT------LEDEIQLKTRAREKGLLVMGPD 174
           ++ V       + +  +   +  VM+ S   +       E E ++  + R  G  ++GP+
Sbjct: 72  VLVVPASQVLSVIDDVIAAGIKHVMILSSGFSDMDKPGEELEREISEKLRAAGCRLIGPN 131

Query: 175 CGTSMI----AGTPLAFANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
               +          +FA  +PE G++ +   SG     +    A  G G+   + LG R
Sbjct: 132 SLGLIQMDSETRLNASFAPKVPEYGHVAIASHSGALGITILDYAAYIGLGVASFVSLGNR 191

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
                   +S    L+    D   E++    +          +       KP +A+    
Sbjct: 192 ------ADVSGNDLLQYWGDDPAIEMILLYLESFGNPRNFSRLARRITRQKPILAVKSAR 245

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGL 349
           TP      N    S   E A +  +  +    R             L  G T        
Sbjct: 246 TPVGHDVANARTVSVAAEDATVEAMFQQAGVIRVDTLQELFDVAVLLKAGPT-------R 298

Query: 350 LAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQ 409
               + V  +      M +D    + ++       VG            +++  +   P 
Sbjct: 299 GGRRVAVVTNTAGGAVMTVDRIVREGLEFVGPVINVG---FETLAESYREVLPQVLRDPS 355

Query: 410 VR-VLLLDVVIGFGATADPAASLVSAWQKACAARLDNQ-----PLYAIATVTGTERDPQC 463
           V  V++L   +G         ++ +A  +                  +A    T      
Sbjct: 356 VDSVIVLFTPVGPSNEEAVRVAISAALCEVANDPPVPGVRHPYEKPVVANFLTT---GDY 412

Query: 464 RSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQH 503
           R + +    +  I +     +A    A ++       +  
Sbjct: 413 RVRMLEVDSERQIPIYPFPEQAVRALAKVVAYHEYREKDP 452


>UniRef50_C0QHU4 SucC3 n=1 Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QHU4_DESAH
          Length = 697

 Score =  216 bits (551), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 92/529 (17%), Positives = 169/529 (31%), Gaps = 82/529 (15%)

Query: 66  VAIRSEAADAGIAQAIM--QQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALI 123
           +A+       G    ++    L     ++   +   + +  +  +          +LA++
Sbjct: 10  IAVVGATPSPGKGGNLIIKNMLNGYDGKIYPVNPRYEQIEGLTCYRDVSDVPDPVDLAVV 69

Query: 124 SVAGEYAAELANQALDRNL-NVMMFSDNVTLEDEI------QLKTRAREKGLLVMGPDCG 176
            V+             R +   M+ S   +   E       QL   A E G+ + GP+C 
Sbjct: 70  FVSSSLVVPTIQACAHRGIAGAMIQSAGFSEAGEQGRKLQDQLVRIASETGIRLWGPNCM 129

Query: 177 TSMIAGTPLAFANV--------MPEGNIGVIGASGTGIQE-LCSQIALAGEGITHAIGLG 227
             + A     F+ V        M  GN+ +I  SG      L   +   G GI+ +  +G
Sbjct: 130 GLVDAVNKRVFSTVETVIWDAGMTPGNVSLIVQSGMLAGAFLIDVMTRGGIGISKSCSIG 189

Query: 228 GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFL 287
            +        +     LE L AD+ + V+    +   +  R   +   + + KP V L  
Sbjct: 190 NKM------DVDESDILEYLMADDDTAVIGLYLESIVDGPRFMDL--CRKSTKPIVLLKG 241

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRN-----------------AIAPVSS 330
           G +   AR      AS     A ++  L++                       A+ P  +
Sbjct: 242 GRSEKGARAAMSHTASLAGNGAVVSGALAQCNVVAATDFNQMMDICRTFGAFTALKPSRN 301

Query: 331 GFICGL-YTGG-----TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYT 384
             +  L Y+GG     T   E AGL    L  E+ +  Q        +   +DL      
Sbjct: 302 KRLAVLTYSGGAGIVSTDFFEDAGLELADLSPESCERIQQVFPDWMPAANPVDLWPGVII 361

Query: 385 VGRPHPMIDPTLRNQLIADLGAKPQVRVL-LLDVVIGFGATADPAASLVSAWQKACAARL 443
            G        ++ N  +  +   P V  + + + V GF    D    + +A         
Sbjct: 362 HGA------KSVYNACLEAVCQDPHVDAVFVHNFVGGFALEPDMDFMVSAA--------- 406

Query: 444 DNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI--HPLSPAAQ 501
            +     +  +TG          +   L   G+ V   +  A    AA +  HP +    
Sbjct: 407 KSVGKPLVCWLTGERHAVHEFQIKAQQL---GLPVFREIHRAVECLAAFMEHHPWADVPV 463

Query: 502 QHT-----PSLLENVAVIN-------IGLRSFALELQSASKPVVHYQWS 538
             T     P  +  +  I+       +        L++   PVV+   +
Sbjct: 464 HDTLETLNPDPVPAIMPISLDNQTGVLDENRSKAILKARGIPVVNETMA 512


>UniRef50_Q8IL89 Succinyl CoA ligase, putative n=5 Tax=Plasmodium RepID=Q8IL89_PLAF7
          Length = 973

 Score =  215 bits (548), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 59/475 (12%), Positives = 137/475 (28%), Gaps = 40/475 (8%)

Query: 42  NKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQ-AIMQQLE--EALKQLAQGSGS 98
           NK +   + F +       P    + I       G    +I+  L   E+  +L   +  
Sbjct: 24  NKNVQHNSYFKNSLDYIFKPRS--IGIIGATERKGSVGNSIVDNLIKGESNYKLYFVNSK 81

Query: 99  SQALTQVRRWDSACQKLPD-ANLALISVAGEYAAELANQALDRNLNVMMF-------SDN 150
              +   + + S      D  +LA+I+V       + ++   +N+  ++        +  
Sbjct: 82  GSKIYNRQSYKSLKDIKEDSIDLAVIAVPRNNVVNVMHELKIKNVRGVVIITAGFKETGA 141

Query: 151 VTLEDEIQLKTRAREKGLLVMGPDCGTSM--IAGTPLAFANV-MPEGNIGVIGASGTGIQ 207
             L  E ++    +   + ++GP+C   +        +FA+  + +G+  ++  SG    
Sbjct: 142 EGLRLENEIINIGKTNNMRIIGPNCLGIIHSYHNMNASFASSDILKGHFSLLSQSGAICS 201

Query: 208 ELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAV 267
                      G +H I +G       +  +     +E L  D  ++ +    +   +  
Sbjct: 202 AALDLSLQHNIGFSHFISVG------SMCDVQFYELVEYLFYDVNTKYILLYVESIGDMN 255

Query: 268 RLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAP 327
           R   V       KP + L  G T   A        S +         + ++         
Sbjct: 256 RFVAVCKKVCLYKPIILLKSGKTAKAAEAAISHTGSMVGNYEIFYATMKKLGVLVVDNFE 315

Query: 328 VSSGFICGLYTGGTLAAEAAGLLAGHLGV-------EADDTHQHGMMLDADSHQIIDLGD 380
                   L +          ++    G           +      + D   + +     
Sbjct: 316 ELFNMCKVLNSSKYPETNEVCVVTNAGGPGVLLVDNIIKNDGVLSNLNDKLKNNLNSFLP 375

Query: 381 DFYTVGRPHPMID---PTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQK 437
           D ++   P  ++    P L  + I  +    Q + ++  V++   +  +P  +       
Sbjct: 376 DSWSKANPIDILGDASPVLYKKTIDAIIKDDQYKNII--VLLSPQSVTEPLDTANEIINL 433

Query: 438 ACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAAL 492
              A    +    +    G         +    L    I        +      L
Sbjct: 434 KKQANEQGRL--ILCNYLGGTA----LEESANMLNKNYIPTFVHPEHSVQNLLKL 482


>UniRef50_D1ABG8 CoA-binding domain protein n=3 Tax=Streptosporangineae
           RepID=D1ABG8_THECD
          Length = 821

 Score =  214 bits (544), Expect = 9e-54,   Method: Composition-based stats.
 Identities = 73/488 (14%), Positives = 146/488 (29%), Gaps = 45/488 (9%)

Query: 66  VAIRSEAADAGIAQAIMQQ---LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   + +A      + +     +    +     ++ A+  VR + +        +LA+
Sbjct: 203 VAVIGASREAHSVGQTVLRHLLAGDFTGPVYPVHPTATAVAGVRAYRTVLDIPDPVDLAV 262

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTL------EDEIQLKTRAREKGLLVMGPDC 175
           ++V  E   E+  Q   + ++ +++ S             + +L   AR  G+ V+GP+C
Sbjct: 263 VAVRAEAVHEVVEQCAGKGVHGLVVVSAGFGETGEEGRARQRELVRLARANGMRVVGPNC 322

Query: 176 GTSMIAGTPLAFANVMPE-----GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
                    +     +       G IG    SG     +  + A  G G++  +  G R 
Sbjct: 323 LGIANTDPAVRLNASLAPTMPGRGPIGFFSQSGALGIAILQRAAERGLGLSTFVSAGNR- 381

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
                  +S    L+    D  + V+    +      +   +    +  KP VA+  G +
Sbjct: 382 -----ADVSGNDLLQYWEEDPATGVVLLYLESIGNPRKFTRLARRISRAKPIVAVKTGRS 436

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLL 350
                  +   A +L + A  + L ++    R          +  L+    L A      
Sbjct: 437 TQGVPLGHAARALTLPDHAV-SALFAQAGVIRV-------DDLDQLFDVAQLLAYQPLPA 488

Query: 351 AGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQV 410
              + +  +      +  DA     + LG          P        + + +  A   V
Sbjct: 489 GDRVAIIDNSNSLGLLAQDAA----VALGLSPREPVDLGPAAGAAEYARALTEALADEAV 544

Query: 411 RVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCR-SQQIA 469
             ++         T      +      A            +AT  G    P+   +    
Sbjct: 545 DAVVALF------TPPTIGEVDPGVATAITRAAAAGAKPIVATYLGAAGMPERLRAPGPD 598

Query: 470 TLEDAG-IAVVSSLPEATLLAAALIHP--LSPAAQQHTPSLLENVAVINIGLRSFALELQ 526
            +  AG +    +  +A    A +          Q   P L E     +         L 
Sbjct: 599 GMPAAGSVPSYPAPEDAVRALAYVTRYALWRRRPQGRLPHLEEADR--DRARALVEELLD 656

Query: 527 SASKPVVH 534
            A  PV  
Sbjct: 657 GADGPVTA 664


>UniRef50_Q6FBA3 Pimeloyl-CoA synthetase n=2 Tax=Proteobacteria RepID=Q6FBA3_ACIAD
          Length = 701

 Score =  211 bits (536), Expect = 7e-53,   Method: Composition-based stats.
 Identities = 68/507 (13%), Positives = 143/507 (28%), Gaps = 49/507 (9%)

Query: 62  NDICVAIRSEAADAGIAQA-IMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDA 118
           N   VA+   + +        ++ L+E+  +      + +   +  +  +         A
Sbjct: 11  NPASVALIGASDNPARIGGRPLRYLKESGFEGEIFPVNPNRDRVQGMLAYADLASLPKAA 70

Query: 119 NLALISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDE------IQLKTRAREKGLLVM 171
           ++AL++V      +   +   + +   ++FS       E       ++   A+E  L ++
Sbjct: 71  DVALLAVPASATVQAVRECAQKGIQTAIVFSAGFAEAGEDGHQMQQEMLNAAKESNLRLL 130

Query: 172 GPDCGTSMIAGTPL--AFANV-----MPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           GP+C     A       F+ V     +  G + ++  SG     +       G GI + +
Sbjct: 131 GPNCLGVFNAYKKFYGTFSTVLDGDFIEPGAVSIVSQSGAYGSHIAHLCRQRGLGIGYWV 190

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK-IVNAMKATGKPTV 283
             G          I    AL  +    + +V+   ++      R    +   +      +
Sbjct: 191 TTGNE------CDIDLSDALNWVVDQPEVKVVLAYAEGIRHRDRFIQALEKAQRNNVAII 244

Query: 284 ALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLA 343
            + +G +   A+  +   A+     A    +L +    R             +   G   
Sbjct: 245 FMKVGRSEVGAKAASSHTAALAGSNAVFDAVLRQYGVIRAKTTTEQIDIAYAVTRAG--- 301

Query: 344 AEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVG----RPHPMIDPTLRNQ 399
                +    LGV          M D      +D+            +  P   P     
Sbjct: 302 ----HIEHNRLGVFTFSGGFGIQMADDAEAAGLDVAPMPEAAQDELKQLLPYASPVNPVD 357

Query: 400 LIADLGAKPQVRVLLLDVVIGFGATADPAASLV-----SAWQKACAARLDNQPLYAIATV 454
             A       +    +  ++  G     A  L        +  A     +     A + +
Sbjct: 358 ATAQALTDLPMMTSFIQTMLKKGDYQFFAGILGSGPTSPTFATALRQTFEEATKDAPSCL 417

Query: 455 -TGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAV 513
              T   P    +Q    E+ G  V            AL+          + S  +    
Sbjct: 418 KCLTMTAPPEIVRQY---EEKGFLVYEDGAALINALGALVKLQQARTATRSSSDFKLPER 474

Query: 514 INI-----GLRSFALELQSASKPVVHY 535
           I I        +    L+ A  P +  
Sbjct: 475 IEIPQREMNEFAAKQILKQAGIPCLPE 501


>UniRef50_Q02CE8 CoA-binding domain protein n=2 Tax=Bacteria RepID=Q02CE8_SOLUE
          Length = 703

 Score =  211 bits (536), Expect = 7e-53,   Method: Composition-based stats.
 Identities = 83/514 (16%), Positives = 156/514 (30%), Gaps = 44/514 (8%)

Query: 66  VAIRSEAA-DAGIAQAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   +   AG+   ++  L E          +    A+T      S  Q     + A+
Sbjct: 21  IAVVGASPGSAGLGARVLANLVEGQFPGQLFLVNPKYPAITGRPCLPSPDQLPQGVDCAV 80

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDC 175
           +++              R +   +        S      ++ Q++  AR  G++V GP+C
Sbjct: 81  LAIPRAGVLNALEGCARRGVGAAIVFSAGYAESGEAGRAEQDQIREIARRSGMVVEGPNC 140

Query: 176 GTSMIA--GTPLAFANV----MPEGN-IGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
              + A  GTPL F          G  + +I  SG     L   +   G  I+ +I  G 
Sbjct: 141 LGMVNAIDGTPLTFVASNPAKPRPGRTLALISQSGALAAVLGVSLRERGLDISFSISSGN 200

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK-IVNAMKATGKPTVALFL 287
             ++           LE L  D  + V+  V +   + +R   +    +  GK    L  
Sbjct: 201 EAVA------GVEDFLEYLIEDPATMVITLVVEQFRDPMRFLDLAERARTCGKRLALLHP 254

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLY-------TGG 340
           G + A          +   +   +   + +      +           L         G 
Sbjct: 255 GSSSAARASAATHTGAMAGDYQVMRTKVRQAGVLMVSTLEELIDVTEILVRCPTLPRAGT 314

Query: 341 TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRP-----HPMIDPT 395
            +  E+    A  L +  +       + DA    +     DF     P       ++DP 
Sbjct: 315 AVFTESGFFKALTLDLCEELGVPLPPLADATHEALRQALPDFIPPSNPLDITAQGLVDPG 374

Query: 396 LRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVT 455
           L  + +  + A  +   ++L +++   + A+ A   +     A       +P+       
Sbjct: 375 LYRRTLPPVLADERYGCVVLSIIL---SEAETAGLKIPPIIAALREIHAEKPVLFACMDE 431

Query: 456 GTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPS-LLENVAVI 514
           G    PQ   +Q   L DAG     S        AA+    +    +  P      V   
Sbjct: 432 GAP-IPQAYIEQ---LRDAGAPYFPSAERTFRALAAVSQSQAEPECEERPRIAPAAVQPG 487

Query: 515 NIGLRSFALELQSASKPVVHYQWSPVAGGNKKLA 548
                     L     PV     +      + +A
Sbjct: 488 VTPEYKAKEILARFGIPVPGGALARTVEEAQAIA 521


>UniRef50_Q2LRG1 Acyl-CoA synthetase n=8 Tax=cellular organisms RepID=Q2LRG1_SYNAS
          Length = 727

 Score =  210 bits (535), Expect = 8e-53,   Method: Composition-based stats.
 Identities = 79/498 (15%), Positives = 166/498 (33%), Gaps = 47/498 (9%)

Query: 32  DVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLE--EAL 89
           D  + + T   K     TG   ++       D    I + +A+  +   + + L   +  
Sbjct: 253 DARMFVSTVPEKTSAARTGSAIEEIRKLFYPDSIAVIGATSAEGKLGYNVFRNLLFHKFS 312

Query: 90  KQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMF-- 147
            +L   +  S  +  V+ + +  +     +LA++ V    A         + + +++   
Sbjct: 313 GKLYPINPKSDEVQGVKAYRNITEVPGPVDLAIVLVPAAAAIAAIEDCCRKGVKIIVVET 372

Query: 148 -----SDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTP----LAFANVMPEGNIGV 198
                +       + +++   R  G  ++GP+C   +         +   + + +GNIG+
Sbjct: 373 AGFAETGEDGKAAQERIREIIRAHGCRLLGPNCSGVINTHVGNVQSIGLVDELGKGNIGM 432

Query: 199 IGASGTGIQELCSQI-ALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLA 257
              +G     + + +  +   GI     +G +        IS    LE L +D+  +V+A
Sbjct: 433 TAQAGVYAAGILTGLRHVMDFGI--VATIGNKM------DISETDILEYLGSDDHIDVVA 484

Query: 258 FVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSR 317
              +      R   V +     KP +AL  G T A  +  +   AS        +    +
Sbjct: 485 MYMEDVKSGRRFIDVASEVTKKKPVIALKGGRTAAGTKVVSSHTASLAGNDEINSAAFRQ 544

Query: 318 VTARRNAIAPVSSGFICGLYTGGTLAAEAAGL--LAGHLGVEADDTH-----QHGMMLDA 370
               R        G +           +   +    G LGV + DT      +   +   
Sbjct: 545 SGIIRARDNEHMFGLLKAFARQPLPRGDGILVITYTGSLGVASTDTLYLNGMRLAELEPE 604

Query: 371 DSHQIIDLGDDFYTVGRPHPM---IDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADP 427
              ++ ++  D+ T   P      +DP    + I    A   V  LL+ +        + 
Sbjct: 605 LKERLREIMPDYVTSMNPVDYSFSMDPEQLRKTIELGIASEDVGGLLVVL------QGEI 658

Query: 428 AASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATL 487
             S V   ++      D +    ++ V   E   +   +    +E AG  + S+   A  
Sbjct: 659 LGSFVDTLKQI-----DYKGKPILSCVACKEFMMEDVIR----MEKAGFPIYSTAEMAAE 709

Query: 488 LAAALIHPLSPAAQQHTP 505
           + A +        +Q  P
Sbjct: 710 ILATMYKYGQKKDRQAQP 727


>UniRef50_D2L2A2 CoA-binding domain protein n=1 Tax=Desulfovibrio sp. FW1012B
           RepID=D2L2A2_9DELT
          Length = 907

 Score =  210 bits (534), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 70/472 (14%), Positives = 140/472 (29%), Gaps = 58/472 (12%)

Query: 59  ATPNDICVAIRSEAADAGIAQAIMQQ---LEEALKQLAQGSGSSQALTQVRRWDSACQKL 115
             PN   VA+   + D     A++ +     + L  +   + +  A++ V  + S     
Sbjct: 10  FRPNS--VAVIGASTDPRHVGAVIMKNLLGGKFLGPVMPVNPALDAISGVLCYKSVDTLP 67

Query: 116 PDANLALISVAGEYAAELANQALDRNLNVMMF--------SDNVTLEDEIQLKTRAREKG 167
              +L +I+   E   E       R +   +                 + ++   A   G
Sbjct: 68  LTPDLGVIATDPESVPEYLRDLGRRGVGAAVVLPPGWAKMPREAKRALQERMLEAAAPSG 127

Query: 168 LLVMGPDCGTSMIAGTPLA---FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           + ++GP     ++ G  L     ++    G I  I  S +    +       G G +H +
Sbjct: 128 IRILGPSGLGLVVPGIGLNCSLASSDALPGRIAFISQSASLFSAVLDWARTKGIGFSHIL 187

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
            LG R        +     L+ ++ D  +  +    +   +A      +   A  KP + 
Sbjct: 188 SLGDR------VDLKYADILDYMAQDPNTRSILLYVESITDARSFMSASRAAARNKPVLV 241

Query: 285 LFLGYTPAVARDENVWFA-SSLDEAARLACLLSRVTARR---------NAIAPVSSGFIC 334
           +  G         +       + + A     + RV                 P+    + 
Sbjct: 242 IKPGRRLWSVFPPDPDEGRDEVYDEAFRRAGMLRVGEIDALFDAAQTLARSKPLRGENLA 301

Query: 335 GLYTGGTLAAEAAGLLAGHLGVEAD------DTHQHGMMLDADSHQIIDLGDDFYTVGRP 388
            L  GG++   AA  L    G  A             +  +   H ++D+  D       
Sbjct: 302 ILTNGGSIGIMAADALLEGGGSLAAYDAEATTALSALLGPNWLRHGVVDMSFDAAPADYA 361

Query: 389 HPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPL 448
             +                P V  +L+  V   G +AD AA+ ++         L     
Sbjct: 362 AALRALLRA----------PDVSAVLVIHVPFPGVSADEAATAMAEV-------LSKTNR 404

Query: 449 YAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
             +A   G +       + +  L  AG+    +  +A      L+       
Sbjct: 405 TILACWMGYDPAG---GEALKILNAAGVPTYETPDQAVSAFVHLLRYRKNQE 453


>UniRef50_A1WNK8 CoA-binding domain protein n=4 Tax=cellular organisms
           RepID=A1WNK8_VEREI
          Length = 711

 Score =  210 bits (534), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 85/529 (16%), Positives = 155/529 (29%), Gaps = 59/529 (11%)

Query: 66  VAIRSEAADAGIAQAIMQQL---EEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VAI   +         + +          L   +  +  L  +  + +        +LA+
Sbjct: 28  VAIVGASDSQDKWGGRLLRYMLRHHHGGALYPINARATELMGLPAYRTLPDCPAAVDLAI 87

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTL------EDEIQLKTRAREKGLLVMGPDC 175
           + V  E+        +++ +   +  +            DE  L   AR  G+ ++GP+C
Sbjct: 88  LLVPREHVYAAIEDCVEKEVGCALCITAGFAETGPKGCADEQALVALARAGGVRLIGPNC 147

Query: 176 GTSMIAGTPLAFANVM--------PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLG 227
              M     L     +        P G IG+   SG  +  + S+    G G +  I +G
Sbjct: 148 MGLMNTHHRLCATTAVVMGGIDTLPAGGIGLASQSGALMGAMISRGVDIGTGFSSTISVG 207

Query: 228 GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRL-KIVNAMKATGKPTVALF 286
            +        +      E L  D  ++V+    +   +A R   ++    A  KP   + 
Sbjct: 208 NQ------SDLDLNDFFEYLIDDPMTDVVCLYMEAVKDAPRFTALLARAAAVRKPVCIVK 261

Query: 287 LGYTPAVARDENVWFASSLDEAARLACLLSRVTA---------RRNAIAPVSSGFIC--- 334
            G + A AR      AS          +  R             + A        +    
Sbjct: 262 SGRSEAGARAAASHTASLAGAWPAFEAICRRWGVYLFETIYDLLQGAQLLQRGKRVESRG 321

Query: 335 -----GLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPH 389
                G    G L A+A       L + +D T      +   SH+ +           P 
Sbjct: 322 VAVTSGSGGAGALLADALEAHGLELPILSDATQLAVQSVLPASHRQLPFDFGMLNHLSPP 381

Query: 390 -PMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPL 448
            P +        +  + A P +   ++ +                A      A   ++PL
Sbjct: 382 DPEVGGGSVGIALDRVMADPAIGAGIVLLTTQPQQERV-------ATAAILVADRSSKPL 434

Query: 449 YAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLL 508
             +      +            L  AG     S  +A  + AAL     PA         
Sbjct: 435 LFV------QGAGNHGDIARQMLRAAGHGYFDSPHDALKVLAALASRTEPAVAAGLLPDG 488

Query: 509 ENVAVINIG---LRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERL 554
              A +  G          L++   P   +Q++    G  + AR +  L
Sbjct: 489 GIPADLPSGFLTEPDARRLLEANGIPTTRWQFAADPEGAVRAARGIGTL 537


>UniRef50_Q7MRU7 Putative uncharacterized protein n=1 Tax=Wolinella succinogenes
           RepID=Q7MRU7_WOLSU
          Length = 644

 Score =  210 bits (534), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 59/446 (13%), Positives = 135/446 (30%), Gaps = 53/446 (11%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
           VAI   + D      AI +       +L   +     L     + +      D ++A++ 
Sbjct: 230 VAIIGASTDESKVGYAIAKNAASFQGELYYVNPKGGELFGRPLFQNVEAIPGDVDMAVLV 289

Query: 125 VAGEYAAELANQALDRNLN-VMMFSDNVT----LEDEIQLKTRAREKGLLVMGPDCGTSM 179
           +          + + +NL  +++ +         EDE+++   A++    V+GP+C    
Sbjct: 290 IPVSSVIPTIEKLVLKNLKNLVIITAGFKESGNEEDELKIAELAKKHNFNVIGPNCLGYY 349

Query: 180 IAGTPLAF---ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVG 236
            A + L     ++ + +GN+ +I  SG  +  L  +      G +H I  G       + 
Sbjct: 350 NAQSDLNLTFGSSNVHKGNLALISQSGAVLASLMDKAYSGNVGFSHLISAGN------MV 403

Query: 237 GISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARD 296
            ++    ++ML AD   E ++  ++      R   + +++ + K       G +    + 
Sbjct: 404 DLNFSEMVDMLVADPACEAISVYAEGIKNGKRF--LRSIRRSHKKIYVFKTGKSEESKKA 461

Query: 297 ENVWFASSLDEAARLACLLSRVTARRNAIAPVS--------SGFICGLYTGG--TLAAEA 346
                 +          LL  V  +                         GG  T+  + 
Sbjct: 462 AFSHTGNLSGNYEMFKGLLEGVGVKMEDNIEALLFNPTYEVQKIAIITNAGGPATILTDY 521

Query: 347 AGLLAGHLGVEADDTHQHGM---MLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIAD 403
                  L     +  +            +  ID+  D            P    + +  
Sbjct: 522 IIEKGKSLHALTKEEIERLDLAMPPHWSKNNPIDIIGDAL----------PERYLKALEI 571

Query: 404 LGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQC 463
           +    ++ ++ L +   F         +  A +     +  +     +  + G +     
Sbjct: 572 VDEFEEIDLIYLLITPQF---------MTDALETVKLLKHKDWKHPVLPILLGGDM---- 618

Query: 464 RSQQIATLEDAGIAVVSSLPEATLLA 489
             Q         +    +L  AT   
Sbjct: 619 VEQAKQFCRSHKMQFFKTLQSATSFL 644


>UniRef50_B2V3D0 CoA-binding domain protein n=6 Tax=Firmicutes RepID=B2V3D0_CLOBA
          Length = 471

 Score =  209 bits (533), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 65/469 (13%), Positives = 137/469 (29%), Gaps = 48/469 (10%)

Query: 62  NDICVAIRSEAA-DAGIAQAIMQQLEEALKQLAQGSGSSQALTQ--VRRWDSACQKLPDA 118
           N   +A+   +  D  +   ++Q L     +      + +A     ++ +        + 
Sbjct: 19  NPKSIAVVGASRYDTKVGYKVIQGLNNWGYKGKIYPVNPRADYVCNLKAYKRVIDIPDEI 78

Query: 119 NLALISVAGEYAAELANQALDRNLNVMMFS-----DNVTLEDEIQLKTRAREKGLLVMGP 173
           +L  I+V       +  Q +++ + +++ +     +    E + +L    R+  L ++GP
Sbjct: 79  DLVFIAVPAHIVKMILKQCVEKKVKIVVIATSAFKEIGRGELQNELTQYCRDNELPLIGP 138

Query: 174 DCGTSMIAGTPLA--FANVMP-EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
           +              F   +P +G + +I  SG  +            G++  +GLG + 
Sbjct: 139 NLVGMGSPYLNFNCGFIPYLPIKGPVAMISQSGANLLAALGTSQSDHFGMSFFVGLGNK- 197

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
                  +     +     DE ++ L+   +          V       KP V + +G +
Sbjct: 198 -----ADVDFCEFISYAGIDENTKCLSVYIEGLDSPEAFIDVCKKFNHKKPIVTIKVGGS 252

Query: 291 PAVARDENVWFAS--SLDEAARLACLLSRVTARRN---------AIAPVSSGFICG---- 335
               +      AS     + A    +     A R          ++A  S   + G    
Sbjct: 253 KIGVKAAFAHTASENEGTDDAYYDEIFEEAGAIRATTWQEFLDMSLALGSQPSLKGENVV 312

Query: 336 -LYTGGT---LAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPM 391
            +  GG    L+ +        L    + +   G  + A         +     G   P+
Sbjct: 313 MITNGGGSGLLSCDHFERCGMPLKELKEISPGLGERIKAYMPMFGSPLNPVDISGTASPI 372

Query: 392 IDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAI 451
                           P V  +L  +        D    +V    +       +     I
Sbjct: 373 ----QYKGAFTQAMRDPNVHGVLGSICPTAVTDVDVVVDIVIELHET----YKHLNKPFI 424

Query: 452 ATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
               G E       + I  L D GI    +  ++     AL        
Sbjct: 425 MECQGGEE----CHRAIMKLRDHGIPAYPTAEQSVNAMLALWKYGKIKG 469


>UniRef50_Q8PZY1 Acetyl-CoA synthetase, alpha subunit n=4 Tax=Archaea
           RepID=Q8PZY1_METMA
          Length = 468

 Score =  209 bits (533), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 59/488 (12%), Positives = 144/488 (29%), Gaps = 56/488 (11%)

Query: 38  GTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGIA-QAIMQQLEEALKQL--AQ 94
           GT  N                  P    +A+   + +       I++ L E   +     
Sbjct: 12  GTENNLDFF------------FKPES--IALIGASPNPEKLSHTILKSLREMNFKGKIYP 57

Query: 95  GSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNV--- 151
            +   + +  ++ + +  +     ++A+ ++      +   +        ++ S      
Sbjct: 58  VNPGYEEIEGLKCYSAPGEINNRIDIAIFAIPARAVLDTLKEPAGNIKGAVIVSSGFREM 117

Query: 152 ---TLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMP-------EGNIGVIGA 201
               ++ E +L+   +EKG+  MGP+C       + +    +            + V+  
Sbjct: 118 GPGGMKMEDELRDLLKEKGIRAMGPNCLGIYDTVSNVDTFFIEREKIERPVRDGVSVLTQ 177

Query: 202 SGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSK 261
           SG+    +  ++A  G G+   +  G +        ++    LE L+ DE ++ +A   +
Sbjct: 178 SGSFAAMIMDELANEGAGVARVVSYGNK------VDVNESDCLEFLAEDEATKAVALYIE 231

Query: 262 PPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTAR 321
             ++  +     +     KP VAL +G     AR  +    +             +    
Sbjct: 232 SVSDGRKFLKAASGCVKKKPVVALKVGKREPGARAASSHTGAISGMYEAYEAAFRKTGII 291

Query: 322 RNAIAPVSSGFICGL------YTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQI 375
             A           L           L     G +   +    ++       L   + + 
Sbjct: 292 EVASYEELKDACKVLNRYSPVNGKRVLIITDGGGIGISIADACEEAGLRVPELSEAAVRK 351

Query: 376 IDLGDDFYTVGRPHPMIDPTLRNQLIADLGAK---PQVRVLLLDVVIGFGATADPAASLV 432
           +      +   R    +  ++R++       +    +  + ++ ++ G          L 
Sbjct: 352 LKEKLPAFASVRNPVDLTGSVRDEHYVAALQETPYEEYDLAIVSLLWGP-------PLLT 404

Query: 433 SAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAAL 492
               +      D+     I +  G     +   +  +     G+ V  S   A   AA L
Sbjct: 405 EGVAEKIKNFADSCGKPVIISSPGG----KFSRELASAFTKTGMPVFFSPESAVRAAAVL 460

Query: 493 IHPLSPAA 500
                   
Sbjct: 461 CGGNGRQK 468


>UniRef50_A3TZP5 Acetyl-CoA synthetase n=1 Tax=Oceanicola batsensis HTCC2597
           RepID=A3TZP5_9RHOB
          Length = 699

 Score =  209 bits (532), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 74/503 (14%), Positives = 153/503 (30%), Gaps = 43/503 (8%)

Query: 66  VAIRSEAADAGIAQAIMQQLE---EALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   + D                    +   +  S  +  +  + S  +     ++A+
Sbjct: 10  VAVIGASGDPKRIGGRPVDFLIRHGFDGPILPINPKSPQVQGLAAYPSISEAPTTPDMAV 69

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLED------EIQLKTRAREKGLLVMGPDC 175
           I++    A +   Q   R +   ++FS   +  D      + ++   ARE G+ ++GP+C
Sbjct: 70  IALPAPLAVQAVEQCAARGVRGAVIFSSGFSEVDADGAALQARMVDIAREGGMRLVGPNC 129

Query: 176 GTSMIAGTPLAFA-------NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
                    L          ++   G + ++  SG       + + + G G+      G 
Sbjct: 130 LGIANVRHNLYATFTPGVEKHLPKPGGVSIVSQSGAFGSYCMTLVRMRGLGVNIWATTGN 189

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEA-VRLKIVNAMKATGKPTVALFL 287
                    +    A+   + D+ + V+    +   +    ++ +   +A  KP V + +
Sbjct: 190 ------SCDVDFADAVAYCAQDDDTRVIMGYLEGATDRDRLVEALEMARAREKPVVMMKV 243

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLY-TGGTLAAEA 346
           G +   A       AS     A       +    R                +G  +  + 
Sbjct: 244 GRSAVGAEAAQSHTASLAGADAVYDAAFRQYGVYRAQSVDEMFDVTYACAESGSMMQGDR 303

Query: 347 AGLLAGHLGV------EADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQL 400
            GL+    GV      EA+        L   + + +     F  V  P  +    +    
Sbjct: 304 LGLVTVSGGVGVLMADEAEKLELDVPALPDHAQKKLKEVLPFAGVRNPVDVTAQLVNQID 363

Query: 401 IADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERD 460
           + +           +D  I F +T    A L  A +       +  P   +   + TE  
Sbjct: 364 LLETNMDVLFGDGEIDGAIIFMSTVGLVADLNEAIRSGLERIREKYPGRPMLFCSLTEP- 422

Query: 461 PQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVIN----- 515
                +  A  E +G  V      A    AAL +     A+      +  ++ ++     
Sbjct: 423 -----EGRAAYEKSGFIVFEEPTRAVRAMAALRYFARSFARAGENDPIPELSNLSPLPDG 477

Query: 516 -IGLRSFALELQSASKPVVHYQW 537
            +        L  A   +VH   
Sbjct: 478 MVNEIEAKALLAEAGIGIVHETL 500


>UniRef50_B0JLR7 Acetyl-CoA synthetase n=2 Tax=Microcystis aeruginosa
           RepID=B0JLR7_MICAN
          Length = 902

 Score =  209 bits (531), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 70/537 (13%), Positives = 151/537 (28%), Gaps = 75/537 (13%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALK--QLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+           + ++  L       +L   +   +    +  + S        +L +
Sbjct: 25  IAVVGFNRQNPQLDRTLLNNLHHNPGQHRLYLVNPHPENRLDLPSYSSLEDIQAAIDLVI 84

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDC 175
           I+        +  Q++++ +   +        +  +      ++K  A +K L ++GP  
Sbjct: 85  ITAPAPEIPAIIAQSVEKKVKCALILSTGFRETGQMGENLLREIKAIAGQK-LRIIGPHS 143

Query: 176 GTSMI--AGTPLAFANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
                        F+ ++P+ G+I +I  SG     +         G +H I LG     
Sbjct: 144 SGISNLSQNLNATFSPILPKTGSIALISQSGAIAAAVLDWSLSENVGFSHFISLG----- 198

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
             +  +     L  L  D +++ +    +    A          A  KP +A+       
Sbjct: 199 -VLLDVDWGELLYYLGDDPQTKSIVIYLESLNNARSFLSSAREVALNKPIIAIS--RHST 255

Query: 293 VAR-DENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLA 351
                          +   L+   +R                  L     LA        
Sbjct: 256 DFDPTALSHAGKLTSDQLTLSAAFARCGIVEVQRLADL------LNITQVLAKIPRFPRG 309

Query: 352 GHLGVEADDTHQHGMMLDADSHQIIDLGD-DFYTVGRPHPMI----------------DP 394
             L + ++      +   A   +   L      T+G+  P++                DP
Sbjct: 310 KRLTIISNGVAPALLAASALLAEDGQLATLTPATIGKLAPLVPADIVPQNPIDLRRSSDP 369

Query: 395 TLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATV 454
               + +    A      +L+ +   F          +       A+   N     +A++
Sbjct: 370 DSYARALEIALADAHTDAVLMILSPRFNTD-------LREIALRIASIAQNSTKPILASL 422

Query: 455 TGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHP-LSPAAQQHTPSLLENVA- 512
            G E      ++ ++ L   GI        A  +   L     +      TP L  +   
Sbjct: 423 MGGE----GIAEGVSLLNQQGIPTYRYPDSAARVFNLLWKYEENLRGLYQTPILTNSREN 478

Query: 513 ------VINIGLRSFALEL----------QSASKPVVHYQWSPVAGGNKKLARLLER 553
                 V  I  ++    +          ++   PV+  + +  A     LA  L  
Sbjct: 479 GSDRVLVSQIIEQAGDRTILSELESLELLKAYGIPVIVTKVAESAAEAVNLAESLGY 535


>UniRef50_C0BX18 Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM
           15053 RepID=C0BX18_9CLOT
          Length = 484

 Score =  209 bits (531), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 60/484 (12%), Positives = 135/484 (27%), Gaps = 54/484 (11%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSG--SSQALTQVRRWDSACQKLPDANLAL 122
           +A+   + +   A   ++  L +            S+  +   + +    +      L +
Sbjct: 14  IAVVGASNNPLKAGYTVIYNLNQIGYPKEVFPVTMSADEILGRKCYKKLSEIEETVELVV 73

Query: 123 ISVAGEYAAELANQAL-----DRNLNVMMF--SDNVTLEDEIQLKTR------AREKGLL 169
           +    +   ++ +         R++ V++   +D    + E  ++ +      A + G+ 
Sbjct: 74  LGTPAKMIYDIMDDLAVRMEKRRDVKVIVCIAADYGETKTEEGIRRQDCLIQTAEKYGIR 133

Query: 170 VMGPDCGTSM--IAGTPLAFANVM-------PEGNIGVIGASGTGIQELCSQIAL--AGE 218
           V+GP+C   +  I      F   +        +G I  I  SG     +    A   A  
Sbjct: 134 VVGPNCIGIIDNINRVDTTFVETLIPKEMRGQKGGISFISQSGAMAASILMMGASGPAPI 193

Query: 219 GITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKAT 278
            +   I +G       +  +  +  LE    D  ++V+    +   +  +L    A  A 
Sbjct: 194 SMNKFISIGN------MADVDCIDLLEYFEQDADTKVIGMYLEGYPDGRKLIDTLARIAR 247

Query: 279 GKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYT 338
            KP V L +G +   A   N    S     +       +    R          +     
Sbjct: 248 KKPVVILKVGRSSIGAEAANSHTGSLAGADSVYDAAFRQFGIIRVYTIEDMMDTLQAFDA 307

Query: 339 GGTLAAEAAGLLAGHLGV--------EADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHP 390
               A     LL    G           +   +  ++ +    ++ D+      +  P  
Sbjct: 308 MKIPAGRNCFLLTQAGGPGIYCTDAFVDEKILKFPLVSEETKRRLADVLPPMANICSPEG 367

Query: 391 MID------PTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLD 444
             D       +   + +  +     V  ++   V+    T  P   L  A  +       
Sbjct: 368 YADITAAATVSHHVESLRAVMDDDAVDSVIFVTVV---PTFLPRRELAEALLRLLVEEGY 424

Query: 445 NQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHT 504
            +       +           +    LE  GI    +        + +         Q  
Sbjct: 425 GKKKPVCICIMAG----NYVWECRQILEQGGIHTFDTPAHCVKAMSHMTAYGQFLKGQEE 480

Query: 505 PSLL 508
            +  
Sbjct: 481 EADE 484


>UniRef50_D2LF69 GCN5-related N-acetyltransferase n=5 Tax=Alphaproteobacteria
           RepID=D2LF69_RHOVA
          Length = 887

 Score =  208 bits (530), Expect = 4e-52,   Method: Composition-based stats.
 Identities = 77/524 (14%), Positives = 147/524 (28%), Gaps = 55/524 (10%)

Query: 66  VAIRSEAADAGIAQAI-MQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   +        I M+ L +          +   +A+  V  + +         LA+
Sbjct: 15  IAVIGASERPRSVGNIVMRNLLDGRFAGPILPVNPRREAVAGVLTYKTVADLPLCPELAV 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG 182
           I   G     +      R     + + +++  D   L   AR   L ++G       +  
Sbjct: 75  ICTPGPAVPGVIEDLGKRGTRAAIVAADMSDPD--ALLAAARRYDLRLLGGASLGVCVPK 132

Query: 183 TPL--AFANV-MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGIS 239
             L   FA++    G +  +  SG             G G +  + LG      +   I 
Sbjct: 133 ANLYANFAHMQAHPGRVAFVSQSGALCAAALDWAKPRGIGFSCVVSLG------DAVEID 186

Query: 240 ALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENV 299
               ++ LS DE+++ +    +   E           A  KP + L  G           
Sbjct: 187 FADMMDYLSKDEETKAILLHIETIRERRGFVSAARAAARNKPVLILKGGNRSTNHPIGQF 246

Query: 300 WFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLG---- 355
              +           + R  A R          +  L     +  E   +L+   G    
Sbjct: 247 LSETLASPDGAFDATVRRAGALRVYSIDELFSAVETLSRTKQVRGERLAILSNAGGAAIM 306

Query: 356 -VEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID------PTLRNQLIADLGAKP 408
            ++  +T + G + D     +  L        RP   +D             +  L    
Sbjct: 307 AIDEINTAERGSIADLSEKTLSQLAKVLPRGRRPANPVDLGAGASADDYTAALKVLSEAL 366

Query: 409 QVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQI 468
           +V  +L   +I        ++ +  A  +A            +A   G E      S  +
Sbjct: 367 EVDGIL---IIHAPNAMTDSSEIARAVVEAQKRYRSG----VLACWLGGE----TASAAL 415

Query: 469 ATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQ----------QHTPSLLENVAVINIGL 518
           A   +AG+   +S+  A      ++      A              P  +   A++  GL
Sbjct: 416 ALFAEAGLCSYNSIGAAVGGFGHIVQHRRNLAMLMETPPADLANFAPDRVTARAIVENGL 475

Query: 519 RS---------FALELQSASKPVVHYQWSPVAGGNKKLARLLER 553
                          L S   P +       A     +A  +  
Sbjct: 476 SRPDGVLSEPDSRRLLASYGIPTLESILVGTADEAAAVAERIGY 519


>UniRef50_B8FGY7 CoA-binding domain protein n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FGY7_DESAA
          Length = 709

 Score =  208 bits (529), Expect = 4e-52,   Method: Composition-based stats.
 Identities = 83/546 (15%), Positives = 153/546 (28%), Gaps = 78/546 (14%)

Query: 66  VAIRSEAADAGIAQAI-MQQLEEALKQLAQGS--GSSQALTQVRRWDSACQKLPDANLAL 122
           VAI   +A+     ++    +                + +  V+ + S         LA+
Sbjct: 17  VAIVGASANPMKMGSMQFLNILHCGFPGTAIPVHPKHEEIFGVKAYPSISSLPDTPELAV 76

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLE------DEIQLKTRAREKGLLVMGPDC 175
           + V       + ++         ++ S             E QL   A + G+  +GP+C
Sbjct: 77  LVVPTGLVINMLDEFGKLGTKHAIIISAGFREMGADGKILEKQLLETADKHGIRFLGPNC 136

Query: 176 GTSMIAGTPLAFANVM---PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
                +  P            G + +   SGT + +  + +   G  +  A+ +G     
Sbjct: 137 MGVFNSQYPFNATVTPFQDKPGFLSIASQSGTYLAQTLTYLKYRGVRLNQAMSVGNE--- 193

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                I+ +  LE L  D K++ +    +  ++  R   V    +  KP VA ++G + A
Sbjct: 194 ---ANINIVDCLEYLGEDPKTKAIGLYIEALSDPGRFLEVAREVSRVKPIVAQYVGGSKA 250

Query: 293 VARDENVWFASSLDEAARLACLLSRVTARRN---------------AIAPVSSGFICGLY 337
            A+       S          L  +    R                      +      +
Sbjct: 251 GAKSGLSHTGSIAGPDFLYNGLFEQAGVIRVHSIEDVYKVGHVLATQPGIKGNRVAVLTH 310

Query: 338 TGGT-----LAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI 392
           +GG        A+  GL+   L  +  D  +  +   A     +DL   F    +P   I
Sbjct: 311 SGGPGSGMCDTADRQGLVVEELPDDVQDKIRAVIPPTASPKNPVDL--TFIVDSKPLSQI 368

Query: 393 DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLD-------- 444
            P         L    +V  LL+  ++  G     A +L  A   +    +         
Sbjct: 369 IP-------QILLECDEVDGLLIHGIMDTGWAKVTAGTLGKALGVSEEDMVKLTKSDLTS 421

Query: 445 ------NQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH---- 494
                       +      + D          + D  I V SS  +A      L      
Sbjct: 422 FLQLKEKYGKPVLVGSFMGDED-----NARNVMMDNFIPVFSSPEKAAFSMGCLYKHHLI 476

Query: 495 PLSPAAQQHTPSLLE-------NVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKL 547
              P ++   P  L          A   +        L     PV     +       + 
Sbjct: 477 KTRPYSKAEKPQGLGKNTASILAQAKGPLDEFQAKRILADYGIPVSPESLASSRDDAVQA 536

Query: 548 ARLLER 553
           A  L  
Sbjct: 537 AESLGY 542


>UniRef50_B2TEE7 CoA-binding domain protein n=1 Tax=Burkholderia phytofirmans PsJN
           RepID=B2TEE7_BURPP
          Length = 750

 Score =  208 bits (529), Expect = 5e-52,   Method: Composition-based stats.
 Identities = 81/544 (14%), Positives = 155/544 (28%), Gaps = 82/544 (15%)

Query: 66  VAIRSEAADAGIAQAIMQQLE---EALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +AI   + D         +          L   +     +  V   DS        +LAL
Sbjct: 22  IAIIGASNDPKSISGQPMRFLMQHGYQGTLYPVNPKYAQIDGVACHDSIAALPSTPDLAL 81

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLE------DEIQLKTRAREKGLLVMGPDC 175
           I VA     ++  Q  ++ +   +++S             + +    A+  G+ V+GP+C
Sbjct: 82  ILVAARRVPDMLRQCGEKGVGFAIVYSSGFAEAGEAGAALQRECADIAKAHGIRVIGPNC 141

Query: 176 ------GTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
                 G ++ AG    F      G + +I  SG     L       G G+ H I  G  
Sbjct: 142 QGFVSTGANVYAGFGAPFGVAYRRGGLSLISQSGGFGCALLLMADELGIGLRHFITTGNE 201

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVN-AMKATGKPTVALFLG 288
                   +S L  +    AD  + ++A   +   +A RL  +       GKP +A  +G
Sbjct: 202 ------ADVSLLDLVNACIADPHTSLIATYIEGLKDAGRLVDMANRALDAGKPLLAWKVG 255

Query: 289 YTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTG--------- 339
            T   A+      A+    +A       +      +       +      G         
Sbjct: 256 NTADGAKAAASHTANLGGASALYRTAFRQTGVIEVSDVADLGDYARAFEAGRLPRGKRIA 315

Query: 340 --------GTLAAEAAGLLAGHLGVEADDTHQHGMMLD---ADSHQIIDLGDDFYTVGRP 388
                   G L  +A       +   +  T +    +    A  +  IDL          
Sbjct: 316 VVTLSGGAGILITDACAERGMSVPALSAATLERLKPIVPAFASLNNPIDL--------TA 367

Query: 389 HPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPL 448
             + +P +    +  +   P        +       A  +  +  A   A      +   
Sbjct: 368 GILAEPKIFADALQIIADDPN-------IDAIAIMAAAASGEVAQAMATAIVRVYGSIDK 420

Query: 449 YAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI--------------- 493
             +              +   T+E  G+ + ++        AAL                
Sbjct: 421 PLMLAWNARRDM---AGEAYETIEAHGVPLYATPVRCGRAFAALADYAQARRARAEARDP 477

Query: 494 --HPLSPAAQQHTPSLLENVA----VINIGLRSFALELQSASKPVVHYQWSPVAGGNKKL 547
               L     +H  +LL ++      +++   +    L+     V     +        L
Sbjct: 478 MPRALRRYDVEHARALLVDIQGKHGDLDLTEHASQALLRDYGIDVPKSGLAQNRDQACAL 537

Query: 548 ARLL 551
           AR +
Sbjct: 538 ARAI 541


>UniRef50_Q1PVJ0 Similar to acetyl-CoA synthetase (ADP-forming) alpha subunit n=1
           Tax=Candidatus Kuenenia stuttgartiensis
           RepID=Q1PVJ0_9BACT
          Length = 462

 Score =  208 bits (529), Expect = 5e-52,   Method: Composition-based stats.
 Identities = 61/470 (12%), Positives = 131/470 (27%), Gaps = 51/470 (10%)

Query: 62  NDICVAIRSEAADAGIA-QAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDA 118
           N   VAI       G     I++ L +          +   + +  ++ + +      + 
Sbjct: 12  NPSSVAIIGATEKTGSVPGIILKNLLDMGFAGRIYPVNPKYREVFGLQCFPALSDISEEI 71

Query: 119 NLALISVAGEYAAELANQALDRNLN-VMMFSDNV------TLEDEIQLKTRAREKGLLVM 171
            L +I++   +  E+  Q   + ++  ++ S          ++ E  ++  A E  + ++
Sbjct: 72  ALTVIAIPASFVLEIVKQQAQKGVHYAVIISAGFREMGAEGIQMEEDIRKVALENNIRII 131

Query: 172 GPDCGTSMIAGTPLAFA-------NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           GP+C   +        +            G + ++  SG     +    A  G GI   +
Sbjct: 132 GPNCLGVLDNYANFTTSFLSWERITKPKRGALSILSQSGAFAITVLDLAAQEGIGIAKMV 191

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVA 284
             G R        +     L  L  D  ++V+A   +      R        +  KP VA
Sbjct: 192 NYGNRM------DVGESDLLPFLKEDHHTKVVAIYMESVDHGRRFIEAAKACSREKPIVA 245

Query: 285 LFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIA--------------PVSS 330
           L +G   A          +             +                       P   
Sbjct: 246 LKVGKGAAGVAAAKSHTGAIAGNYEIYKAAFLKAGIIEANGLEEFIDGIKALSMQSPPMG 305

Query: 331 GFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHP 390
             I  +  GG      A   A +       + +    L     +   + +     G    
Sbjct: 306 NKILIVTNGGGFGVIVADYCAQNGLEVTPPSPELKEKLKEKFAKFYVVNNPVDLTGSACD 365

Query: 391 MIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYA 450
                +    + +  +     V+++ ++   G     +  +VS   +   A      +  
Sbjct: 366 DDYRVVLQTCMVE--SDEYDAVIIIPLMSPKG----MSEKIVSVIDETMKASGKPAVVCT 419

Query: 451 IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
           +  V  T        +    LE+    V  S   +      L+      A
Sbjct: 420 VGGVFAT--------KIKRLLEERHYPVYPSPERSAKAMGMLLERKMLQA 461


>UniRef50_B8F999 CoA-binding domain protein n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8F999_DESAA
          Length = 486

 Score =  207 bits (527), Expect = 8e-52,   Method: Composition-based stats.
 Identities = 77/466 (16%), Positives = 136/466 (29%), Gaps = 52/466 (11%)

Query: 70  SEAADAGIAQAIMQQLEEALKQLAQGSGS--SQALTQVRRWDSACQKLPDANLALISVAG 127
                   A  +M  + +          S     +  V       Q     +LA ISV  
Sbjct: 23  GVTKFGSFANFVMLSIMKYGYAGKIYPISDKGGDVLGVPAIAGLEQADGPVDLASISVPA 82

Query: 128 EYAAELANQALDRNLNVM--MFSDNVTLEDEIQL-----KTRAREKGLLVMGPDCGTSMI 180
           +   E+  Q L   +  +    S    + DE  +           KGL ++GP+C     
Sbjct: 83  KAVPEILEQCLQNGVAGVQVHTSGFAEMGDEEGIALQKQLEEYAAKGLRIVGPNCFGIHC 142

Query: 181 AGTPLA----FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVG 236
               L     F      G+  +I  SG    +   + ALAG GI+  +  G         
Sbjct: 143 PKGGLTVLPGFDFNKQPGSCSMISQSGGLANDFGHEAALAGLGISKVVSFGNG------C 196

Query: 237 GISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARD 296
            + A+  +E L+ D ++E +A   +  A+A     V    A  KP +    G TP   R 
Sbjct: 197 DLDAIALMEYLADDPQTEYIAAYIEGVADAGAFLDVVRKTAAKKPVIIWKGGLTPLGGRA 256

Query: 297 ENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGL-------------YTGGTLA 343
                 S   E+      L++  A            + GL               GG + 
Sbjct: 257 TLSHTGSMGGESKIWEGALAQAGAYAVQGLDEMMDTLMGLVYTKSRGKKIALVGGGGAIG 316

Query: 344 AEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIAD 403
              + L           +++    L        +   +    G P   +D  +    + +
Sbjct: 317 VFTSDLAYRWGLEIPVFSNETQKKLRTYFPTPGNSMKNPLDTGTPALPLD--VLKGCVTE 374

Query: 404 LGAKPQVRVLLLDVVIG------------FGATADPAASLVSAWQKACAARLDNQPLYAI 451
           +     V V++L ++              +G    P    V +  +      +       
Sbjct: 375 ILTAEPVDVMILILLTHPLETVSSTFCKMYGLEPPPPGQYVDSLFETLTGLREQTGKDLA 434

Query: 452 ATVTGTERDPQCRS-----QQIAT-LEDAGIAVVSSLPEATLLAAA 491
                     +        +Q+    + AGI V +S   A      
Sbjct: 435 LVFENRAYRLEDMEADAAWRQLRVKYQAAGIPVFASAERALRAVRN 480


>UniRef50_D1C154 CoA-binding domain protein n=1 Tax=Sphaerobacter thermophilus DSM
           20745 RepID=D1C154_SPHTD
          Length = 743

 Score =  207 bits (527), Expect = 9e-52,   Method: Composition-based stats.
 Identities = 69/477 (14%), Positives = 152/477 (31%), Gaps = 38/477 (7%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLALI 123
           +AI   +   G A  I ++L +   +      + +   +  +  + S        +LA++
Sbjct: 34  IAIVGASPKRGFANNIQRRLVDCGFEGEVYPVNPNYDEILGLPCYPSLEAIPGGVDLAVV 93

Query: 124 SVAGEYAAELANQALDRNLNVM-MFSDNVTLEDE--------IQLKTRAREKGLLVMGPD 174
            V       +        +  + + +     + E          ++  AR  G+ V+GP+
Sbjct: 94  VVPSRLIPGVLESCERAGVGAVNIITSGFAEKQEDETGPERQRAIRDFARRTGIRVVGPN 153

Query: 175 CG-TSMIAGTPLAFANVMPE---GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
           C     +    +A +   P    G I +   SG     L       G G T+ + LG   
Sbjct: 154 CLGNISVPNRMVASSGAYPPLNRGPIALALQSGLLAYSLVLPAHDRGIGFTYVVTLGNE- 212

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAE-AVRLKIVNAMKATGKPTVALFLGY 289
                  I  +  +     DE++ V+    +        L++       GKP V L +G 
Sbjct: 213 -----ADIDVVDMIRYYLDDEETRVIGCFVEQFRRLERLLEMAERAADLGKPIVVLKVGR 267

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGL 349
           + A  R       S +     +  ++ +    R          +   ++    A    G+
Sbjct: 268 SEAGRRAALAHTGSLVGSDEIVDAVMRQHGIIRVYSLDEMIETLALFHSRRRPAGRGVGI 327

Query: 350 L---AGHLGVEADDTHQHGMMLDADSHQIID----LGDDFYTVGRPHPMID-----PTLR 397
                G  G+ AD     G+   + + + ++    +  ++ TVG P          P + 
Sbjct: 328 AVVSGGAAGLIADLGADIGVEFPSLAPETVEKMNAVIPEYGTVGNPLDYTGQAAQQPEIL 387

Query: 398 NQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGT 457
           +  +A +   P + V++      + A  D                 D +    ++ V G 
Sbjct: 388 DGCLAAMAEDPNIHVVVYGQ--AYPALIDLDQPTGQVLSALPERYPD-KVFVVLSLVAGE 444

Query: 458 ERDPQCRSQQIATLED-AGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAV 513
            +      + +  +    GI  +          A+L+   +   ++   +  +    
Sbjct: 445 LKHRMIDQEAVEPVRSIDGIPFLQGAENGLRAIASLVRYAAFLREREASARADARDP 501


>UniRef50_B8FEI4 CoA-binding domain protein n=2 Tax=Deltaproteobacteria
           RepID=B8FEI4_DESAA
          Length = 468

 Score =  206 bits (524), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 65/468 (13%), Positives = 140/468 (29%), Gaps = 46/468 (9%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSS--QALTQVRRWDSACQKLPDANLALI 123
           VAI          +  +  +++   +      +     +  ++ + S        ++A+I
Sbjct: 21  VAIVGLPRGMKTGKLFLIAIQDMGFKGPIYPVNPFTDEIDGLKSYPSVEALPEPVDMAII 80

Query: 124 SVAGEYAAELANQALDRNLN-VMMFSDNVTL-------EDEIQLKTRAREKGLLVMGPDC 175
            V    A E   Q  ++ +   ++F+              E ++ + A++ G+ ++GP+ 
Sbjct: 81  LVPNSQAKEAVVQCAEKGVKGAVLFTAGYKETGEEEGAALEEEMASIAKKAGMRLIGPNG 140

Query: 176 GTSMIAGTPLAFANVMPE--GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
                    ++F   +P   G I ++  SG+    LC      G     A+ LG      
Sbjct: 141 MGLYSPEAGISFFPGLPAKLGPIALLSHSGSMANILCRMGPEKGLYFRFAVSLGNE---- 196

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAV 293
               ++A   LE  + D K+ ++A   +   +           +  KP +   +G  P  
Sbjct: 197 --CDLTAGDFLEYCAQDSKTGIVAAYLEGIRKGDVFLKNLKKASENKPVILWKMGLNPEG 254

Query: 294 ARDENVWFASSLDEAARLACLLSRVTARRNAIAPV--------------SSGFICGLYTG 339
           A        S   +      ++S+  A                             +   
Sbjct: 255 ASAAASHTGSMAGDERIWNAVVSQARAVSVNGFEEWVDAMMGFSLLPRGMGRRAAIISGP 314

Query: 340 GTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQ 399
           G LA  AA          A  + +    L     Q      +   +G  +  +D +L  +
Sbjct: 315 GGLAVSAAQACGRAGLTLAALSTESREKLAEFVPQTGTSLKNPVDIGM-NSSLDMSLYIR 373

Query: 400 LIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTER 459
               +   P V  +++   IG     +       A  +A            +       +
Sbjct: 374 AAQIMAEDPNVD-IVMAAPIGLSLETN------HALTQALIDVYKTAGKPFVMI-----K 421

Query: 460 DPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSL 507
            P   ++       AG+    S   A      +++        H  + 
Sbjct: 422 IPGFEAECAQEFCQAGVPFFDSAERAA-ATCGMVYNWQKQRGLHKQTP 468


>UniRef50_Q7WE41 Putative acetyl-CoA synthetase n=2 Tax=Bordetella
           RepID=Q7WE41_BORBR
          Length = 713

 Score =  206 bits (523), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 72/524 (13%), Positives = 155/524 (29%), Gaps = 58/524 (11%)

Query: 66  VAIRSEAAD-AGIAQAIMQQLEEALKQLAQGSGSSQ--ALTQVRRWDSACQKLPDANLAL 122
           +A+   + D       I+  +     +      + +   +  +    S    L   ++A+
Sbjct: 27  IAVVGASDDLKKFGGRIIHYVTRNGYRGTVIPVNPRRAEVAGLPAVPSI-AHLGPVDVAI 85

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNV-------TLEDEIQLKTRAREKGLLVMGPDC 175
           +++  +   +   +     +   +             +  + ++   ARE G+ ++GP+C
Sbjct: 86  LALPVDMIEQAIGECAAAGVGACVIVSAGFAELGDEGVARQDRIVRIAREAGMRLVGPNC 145

Query: 176 GTSMIAGTPLAFA-------NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
              +     +A           +  GNIG+I  SG  +  +  +        +  + LG 
Sbjct: 146 MGIINPHHRMALTSSLVVEQGELLPGNIGLISQSGALMVSMYDRACREQIRFSACVSLGN 205

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMK-ATGKPTVALFL 287
           +        +      E +  D  + V+    +   +  R   +       GKP +    
Sbjct: 206 Q------CDLEICDFFEYMIDDPLTRVITMYVEGFVDTGRFAELARRAQRAGKPVLLTKT 259

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAA 347
           G T A A       AS       L  L                     L   G  AAE  
Sbjct: 260 GRTAAGAEAARSHTASLAGNYRALEALCEATGVTIVDDPDGMLQLAAILARFGRCAAEGV 319

Query: 348 GLLAGHLGV------EADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI-----DPTL 396
           G+++   G          D       LDA S Q++    +      P  +      + + 
Sbjct: 320 GIVSPSGGAIGIGVDRLSDVGIRLGRLDAASQQLLGTVMNPSHAFNPVDLGNRTTEEMSQ 379

Query: 397 RNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTG 456
              ++      P + V+   V++      +     +        A+   +P+  + T   
Sbjct: 380 LRTIVQAYNQAPDIGVI--FVILTTSPHFEQVTLALGQ----AMAQAGGKPVLFLVT--- 430

Query: 457 TERDPQCRSQQIA-TLEDAGIAVVSSLPEATLLAAALI--------HPLSPAAQQHTPSL 507
               P   +      L+D G+  V  + +A  +    +              A    P  
Sbjct: 431 ----PGGVADNCRTLLQDLGLPYVDRMDDAIRILRHYVPKADALPARDAPRPASWPMPEG 486

Query: 508 LENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLL 551
              +     G       L++   P+   ++   A    + AR +
Sbjct: 487 AGRMLGARPGEPEVKALLRAYGIPLAQERFCRTAEQAVEAARAI 530


>UniRef50_C5EFZ7 Putative uncharacterized protein n=1 Tax=Clostridiales bacterium
           1_7_47FAA RepID=C5EFZ7_9FIRM
          Length = 693

 Score =  206 bits (523), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 91/502 (18%), Positives = 159/502 (31%), Gaps = 50/502 (9%)

Query: 66  VAIRSEAADAGIAQAIMQQ---LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +AI   +  AG      +      + L QL   +     +   R + S  +   D +L +
Sbjct: 12  IAIVGASEKAGFGGDTTRNYLKFSKNLDQLYLVNPGRDTIFGRRAYHSLSEIEGDVDLVI 71

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTL------EDEIQLKTRAREKGLLVMGPDC 175
           +    +    L  +A  +N    ++F+           E + +L   A   G+ VMGP+C
Sbjct: 72  LCTPQKTIIPLLEEAAGKNCGGAVVFASGYGEVGPEGRERQRELVEAADRLGIAVMGPNC 131

Query: 176 GTSMIAGTPL-AFANVM----PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
                    + AFA ++      GNIG+I  SG   Q +   +     G +H I  G   
Sbjct: 132 AGFANFVDGIFAFAFLVEERERGGNIGMISQSG---QIVLGGLDSPNMGFSHVISSGN-- 186

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKA-TGKPTVALFLGY 289
                  +     L+ L  DE ++V+A   +   +  +L       A   KP V L  G 
Sbjct: 187 ----SCNVKVEDYLDFLVDDEDTKVVAAYMEGVTKPEKLVAAFQKAALKKKPVVVLKTGR 242

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARRN------AIAPVSSGFICGLYTGGTLA 343
           +            S       L  +  R                 +  ++  L  G    
Sbjct: 243 SSKSQELAKSHTGSLSGADKVLRAVFKRYGVVEAGDLEELMSLAAAFSWLEELPKGERCV 302

Query: 344 AEAAGLLAGHLGVEADDTHQHGMML----DADSHQIIDLGDDFYTVGRPHPMIDPTLRN- 398
                +  G  GV AD + ++G+ L          +  L  D+ +V  P  M      N 
Sbjct: 303 F--MNVSGGEAGVMADLSEEYGIRLAEMQQETKAYLKTLVPDYGSVNNPFDMTAGIGYNT 360

Query: 399 ----QLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATV 454
               Q +  +   P V  +++   I      D  + +V A      AR D          
Sbjct: 361 PVMVQAMEAISKDPGVDAIVVAYTITPEIWDDTISHMVEAVS---IARRDKTLKPV---F 414

Query: 455 TGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVI 514
                +     +    L+ AG  ++ +          ++       +   P++ E     
Sbjct: 415 WIPFIEHTRHQESADILKAAGTPLLPTGRYGCTALKKILDFAVRTFEPMEPAVPEGKHEC 474

Query: 515 NIGLRSFALE--LQSASKPVVH 534
           +  L  F     L S   PV  
Sbjct: 475 SHSLSEFESLNYLSSHGVPVPP 496


>UniRef50_A7HF64 GCN5-related N-acetyltransferase n=1 Tax=Anaeromyxobacter sp.
           Fw109-5 RepID=A7HF64_ANADF
          Length = 812

 Score =  206 bits (523), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 82/473 (17%), Positives = 139/473 (29%), Gaps = 55/473 (11%)

Query: 65  CVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQAL--TQVRRWDSACQKLPDANLAL 122
            +A+            I++ +     +         A     VRR  S  +   + +LA+
Sbjct: 14  AIAVFGAGERESPGDLILRNVVAGGFEGPIHVVGEAAELPAGVRRCASLAELEGEVDLAI 73

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSD--------NVTLEDEIQLKTRAREKGLLVMGPD 174
           ++       E+     +R++   + +              D       A   G+ ++GP+
Sbjct: 74  VAAPPASIPEIVGACAERHVAGAVIAASASGSVGPGEPDPDAAAALLAAARGGVRLLGPN 133

Query: 175 CGTSMIAGTPLAF---ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
                     L     +     G+IG++  SG          A    G +  + LG    
Sbjct: 134 SVGLARPDARLNATFTSGSASPGSIGLVSQSGALCATALDWAAAHRIGFSAVVSLG---- 189

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
             +   +     LE L+ D  ++ +    +    A        + A  KP V +  G   
Sbjct: 190 --DALDVDFGEVLEYLALDPATKSVLLYVETLRAARPFLSGLRLAARLKPVVVVKAGRHG 247

Query: 292 AVARDENVWFASSLDEAARLACLLSRVTARR---------NAIAPVSSGFICGLYTG--- 339
           A A       +    +AA       RV +               PVS   +  +      
Sbjct: 248 AGADGAPPASSDDAFDAALARAGAVRVESMDRMFAAARLLATPRPVSGNRLAVVTNARGP 307

Query: 340 GTLAAEAAGLLAGHLGVEADDTHQHGMML--DADSHQIIDLGDDFYTVGRPHPMIDPTLR 397
           G LAA+ A  L   +   AD T      L  ++     +DL  D           DP   
Sbjct: 308 GLLAADRADELGVVVAPLADATRTALDALVPESARSNPLDLLGDA----------DPARY 357

Query: 398 NQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGT 457
              +      P V  +L   V+   A + PA +       A  A         +A   G 
Sbjct: 358 RSAVELCLGDPNVDAVL--AVLAPYARSLPAET-----ADAVVAASRGGSKPIVACWMGE 410

Query: 458 ERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI-HPLSPAAQQHTPSLLE 509
           E          A   +A +   SS   A    A L  H  +    +  P  L 
Sbjct: 411 EL----VRSARARFVEARLPDFSSPEAAVDAFALLASHARNQRLLRQVPGPLA 459


>UniRef50_A5G5K1 CoA-binding domain protein n=2 Tax=Desulfuromonadales
           RepID=A5G5K1_GEOUR
          Length = 451

 Score =  205 bits (522), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 68/457 (14%), Positives = 134/457 (29%), Gaps = 55/457 (12%)

Query: 66  VAIRSEAADAGIAQAIM-QQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
           +A+   +AD      ++ + L     +    + +   + +V  + S        +L++I 
Sbjct: 13  IALIGASADEKRLGGVVSRNLRAFRGKFYPVNPNYTEIDEVPVYASIRDLPETVDLSVIL 72

Query: 125 VAGEYAAELANQALDRNLNVMMFSDNVTL----EDEIQLKTRAREKGLLVMGPDCGTSMI 180
                  EL      +    ++ S           + ++    RE G+ ++GP+C     
Sbjct: 73  RPAPEVPELLAAHAGKARCAIIVSAGFAETGCESLQQEVVRLGRELGIRLLGPNCLGVFA 132

Query: 181 AGTPLAFANVMP-------EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
               L    +         +GN+ V+  SG  +  L   +A++G G++  +  G      
Sbjct: 133 PYQRLDTLFLPRERLKRPKKGNVAVVSQSGALLLCLLETLAVSGRGVSLGVNYGN----- 187

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAV 293
               I      + L+ D ++ V+    +  A+  R        A  KP + L  G   + 
Sbjct: 188 -AADIDGADIYDYLAEDLETGVVISYLESMADGRRFVAAAEKLAQRKPLLILKAGKGESG 246

Query: 294 ARDENVWFASSLDEAARLACLLSRVTARR--------------NAIAPVSSGFICGLYTG 339
            R           +    + ++ +   R                   P     IC +   
Sbjct: 247 QRAAYSHTGRLAGKYEVFSSIMRQSGIREVRDLDELLDAGHALARQRPSRGNRICIVTNA 306

Query: 340 GTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQ 399
           G L   AA   A H              L    H        FY+V  P  +      ++
Sbjct: 307 GGLGVLAADECARHGIEITPLPEAIRQRL----HNCF---PPFYSVANPIDLTGQVKDDE 359

Query: 400 --LIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGT 457
                +         L++       A        +    +             +A +   
Sbjct: 360 YLATLNEIQDEYDGFLVI-------AHTGVVGLTLR-LAELLTVFRAASGKPLVAYLA-- 409

Query: 458 ERDPQCRSQQ-IATLEDAGIAVVSSLPEATLLAAALI 493
              P   + Q    LE   I V  S   A    ++L+
Sbjct: 410 ---PGGITDQLAKRLEKGEIPVYPSPERAVRGLSSLM 443


>UniRef50_A0KEL7 Acyl-CoA synthetase n=2 Tax=Aeromonas RepID=A0KEL7_AERHH
          Length = 858

 Score =  205 bits (522), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 62/452 (13%), Positives = 126/452 (27%), Gaps = 42/452 (9%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   + D   A   +++ L     +      S  S A+  V  +          +LA+
Sbjct: 15  IAVIGASTDPQKAGHVVIRHLLAGQFKGPILPVSPHSTAIAGVLAYGDIDSLPLAPDLAI 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDN-VTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           +    E    L      R     +      T  +  QL+  +++ G+ ++GP+    ++ 
Sbjct: 75  VCTRRERVLTLIEALGKRGAGAAIILAADFTAPEREQLQQLSQQYGIRLLGPNSMGMLLP 134

Query: 182 GTPLAFANVM---PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGI 238
           G  +  +        G +  +  S      +         G +  I LG      +   I
Sbjct: 135 GQGINASFSPIAAKPGQVAFLSQSAAVSTTILDWAKQHELGFSAFISLG------DHCDI 188

Query: 239 SALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDEN 298
           +    L+ LS D  +  +        +A          +  KP + L  G          
Sbjct: 189 NFGQLLDQLSRDSVTRAILLYMDKLQDARHFLSAARAASRNKPILVLKSGRHEPDN---- 244

Query: 299 VWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEA 358
                           + R    R          +  L    TL  E   +++   G+  
Sbjct: 245 -------GLDNVYDAAIRRAGMLRVRDTHELFAAVETLSHSLTLKGERLAIISNGRGLAN 297

Query: 359 DDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVV 418
               +        +    D+G D           D     Q + DL    +   +LL   
Sbjct: 298 MAIDKLLERGGKLAMPPRDIGSDA----------DINDYQQALDDLLQGDEADAILL--- 344

Query: 419 IGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAV 478
           I   +     A+L  +           +    +    G         +      +AG   
Sbjct: 345 IHAPSLTARGAALARSLIDYVKQHPRARRFNILTNWAGE----YSAQEGRRLFSEAGFPT 400

Query: 479 VSSLPEATLLAAALI-HPLSPAAQQHTPSLLE 509
             +   A      ++ +  +      TP+ L+
Sbjct: 401 YRTPESAVAAFMHMVEYRRNQKQLMETPASLQ 432


>UniRef50_A9ICA6 Acetyl-CoA synthetase n=1 Tax=Bordetella petrii DSM 12804
           RepID=A9ICA6_BORPD
          Length = 704

 Score =  205 bits (522), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 76/523 (14%), Positives = 156/523 (29%), Gaps = 44/523 (8%)

Query: 62  NDICVAIRSEAADAGIAQAI---MQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDA 118
           N + +A+   +AD            +L      +   +    A+  ++ + S      D 
Sbjct: 15  NPLSIAVIGASADEDKIGGRPIKYLRLAGYSGPIYPINPKRDAIHGLKCYPSITAVDDDI 74

Query: 119 NLALISVAGEYAAELANQALDRNL-NVMMFSDNVTLEDEI------QLKTRAREKGLLVM 171
           +LA+ISV  +         + + +  V++FS   +  DE       ++   A E G+ ++
Sbjct: 75  DLAIISVPAQEVLSAVESCVAKRVSGVLIFSSGFSEVDEAGRILQERIVQLASEGGVALL 134

Query: 172 GPDCGTSMIAGTPLAFANV-------MPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           GP+C  +      L               G+I  +  SG     +         G++  +
Sbjct: 135 GPNCAGTFNTRAGLLATFSSGILDKPPQPGSISFVSQSGAFGINMLVLAGERDLGLSMCL 194

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAE-AVRLKIVNAMKATGKPTV 283
             G +        +    AL  ++ D ++EV+    +   +    L  +   +   KP +
Sbjct: 195 TSGNQ------ADVDVAEALAYMAQDPETEVIGVCIEGIPDFDRFLAAIELARRNRKPVI 248

Query: 284 ALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLA 343
            L LG +   AR      AS          +L + +  R                     
Sbjct: 249 VLKLGRSEVGARAVASHTASIAGSDEVFDAILRQYSVCRAHSIEELLDIAYA-------C 301

Query: 344 AEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGD----DFYTVGRPHPMIDPTLRNQ 399
           +         LG+         +  D  S   +D+ +        +    P         
Sbjct: 302 SLRRHPPNDKLGIITVSGGVGILTADQASAAGLDVAELPAQPQAAIKALLPFAAAGNPVD 361

Query: 400 LIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTER 459
           + A +  +P +   + + ++  G  +  A        +    ++        +   G   
Sbjct: 362 VTAQITTQPALVEPMFEHMLAGGYGSSIALFTYLPRNRVLFEKMLFYFERVASRYPGHFF 421

Query: 460 DPQCR--SQQIATLEDAGIAVVSSLPEATLLAAALIHPLS----PAAQQHTPSLLENVAV 513
                  S+    LE  G AV      A     AL+        P+A +    +L   +V
Sbjct: 422 VICALTDSEMRTRLESMGYAVFDDPGRAVRAIRALVDFQKAFDLPSAVREAVVMLGAKSV 481

Query: 514 INIGLR---SFALELQSASKPVVHYQWSPVAGGNKKLARLLER 553
               +         L  A  P +  +           A+ +  
Sbjct: 482 RRGAVYDEFQAKKLLALAGIPGLPEELVSSVDQALGAAKRIGY 524


>UniRef50_B9LS76 CoA-binding domain protein n=9 Tax=Halobacteriaceae
           RepID=B9LS76_HALLT
          Length = 704

 Score =  205 bits (521), Expect = 4e-51,   Method: Composition-based stats.
 Identities = 57/457 (12%), Positives = 116/457 (25%), Gaps = 37/457 (8%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISV 125
           VA+    +  G     +               +      +           DA++A+I V
Sbjct: 13  VAVVGATSREGAVGRAVTSNLLDDFDGDTVPVNPNYDEVLGTPCVDEVADADADVAVIVV 72

Query: 126 AGEYAAELANQALDRNLN-VMMFSDNVTL------EDEIQLKTRAREKGLLVMGPDCGTS 178
                 +      +  +  V++ +             E +L   A E  L ++GP+    
Sbjct: 73  PPSIVLDAIEACGEAGVRNVVVITAGFGETGEDGAARERRLAEIADEYDLNLVGPNSLGI 132

Query: 179 MIAGTPLAFANVMP---EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREV 235
           M   + +           G +  +  SG  +  +       G G    + LG + +    
Sbjct: 133 MSTPSGMNATFGPENALPGGLSFMSQSGAFVTAVLDWANDNGIGFKDVVSLGNKAV---- 188

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVAR 295
             +     ++    DE+++V+    +   +               P VA+  G T A A+
Sbjct: 189 --LDETDFVDHWGNDEETDVIIGYLEGIEDGREFIEAARETTQDTPIVAVKSGRTSAGAQ 246

Query: 296 DENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLG 355
             +    +           L +    R             L +      ++  ++    G
Sbjct: 247 AASSHTGTLAGSDKAYEAGLDQAGVIRAESVDELFDSAGILGSQPLPDTDSVAIVTNAGG 306

Query: 356 V-------EADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI---DPTLRNQLIADLG 405
                     D            S  + +   D   +  P  +I   D     + +    
Sbjct: 307 PGVMATDAVGDADLDMASFTKKTSDALRESMPDEANIHNPVDVIGDADVERFREALEITV 366

Query: 406 AKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRS 465
               V   L+          D           A     D       A + G +       
Sbjct: 367 DDDNVGAALVLAAPTATIDFD-------DLADAIGEVSDEMDAPVAACLMGGD----RTR 415

Query: 466 QQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQ 502
           +    L+  GI             A L       A++
Sbjct: 416 EPKQQLQAKGIPCYFDPARGIESLATLGRYRDIKARE 452


>UniRef50_B7X585 CoA-binding domain protein n=2 Tax=Comamonas testosteroni KF-1
           RepID=B7X585_COMTE
          Length = 707

 Score =  204 bits (520), Expect = 5e-51,   Method: Composition-based stats.
 Identities = 78/523 (14%), Positives = 158/523 (30%), Gaps = 38/523 (7%)

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQ--GSGSSQALTQVRRWDSACQKLPDAN 119
           N   VA+      +  ++     L+    +      + S   +   + + +A       +
Sbjct: 13  NPRSVALVGATDRSTWSKMAFDNLKLLGFEGKVHLVNRSGGVVHGQQSFKTAVDIGESVD 72

Query: 120 LALISVAGEYAAELANQALDRNLN-VMMFSDNVTLE------DEIQLKTRAREKGLLVMG 172
           +AL+ V      +         +   ++ +             + ++   ARE G+ ++G
Sbjct: 73  VALLMVPNPAMEDALRDLGAAGIRHAVVLAGGFAETGSEGRTMQERMVATARELGITLLG 132

Query: 173 PDCGTSMIAGTP-LAFANVMP----EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLG 227
           P+C   +   T  + +   M     +G I ++  SG     +       G G+      G
Sbjct: 133 PNCLGFINFTTGAVCWTGAMRTPPLKGGISIVSQSGAVATVMKHFAHQHGVGMNVVAATG 192

Query: 228 GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGK-PTVALF 286
              +      +     ++ L  DE ++V+A  ++   +    +           P V L 
Sbjct: 193 NEAM------LGLAECVDYLVDDESTKVIAVFAETVRDTRLFRAAAERALAKAKPIVVLK 246

Query: 287 LGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEA 346
           +G +    +       S + + +    +  ++   R             L   G LA   
Sbjct: 247 VGRSDIATQAAQSHTGSLVGDDSVFDGVCRQLGLVRVRSIEELVFTAALLEKTGVLAEGG 306

Query: 347 AGLLAGHLG---VEADDTHQHGMMLDADSH----QIIDLGDDFYTVGRPHPMI-----DP 394
             +L+   G   + AD      + L A S+     + ++     T   P  +      DP
Sbjct: 307 VAVLSSSGGMGELAADYAQLETLRLPALSNETLSALREILPPMATPANPLDLTGAVVNDP 366

Query: 395 TLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATV 454
            L  + +  +   P V VL+    +      D A   V   Q     + D +  Y + + 
Sbjct: 367 ALFTRCMDAMQRDPAVSVLVCVADVPTANNNDWAPFAVGTLQAIGQFKPDGRARYLVVSN 426

Query: 455 TGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLE----- 509
           T      + R +            +     A   AA        A  +     L      
Sbjct: 427 TVKAVSDKSREEVEKAQIPYLACGLDIALRALRYAADWSRMSRSAGGERAARALPGAAST 486

Query: 510 NVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLE 552
             A +    R     L+    PVV    +  A      AR + 
Sbjct: 487 AGADLPQSERETVDYLKRFGVPVVPQVLATDAKQAVAAARDMN 529


>UniRef50_D2RRG3 CoA-binding domain protein n=1 Tax=Haloterrigena turkmenica DSM
           5511 RepID=D2RRG3_9EURY
          Length = 709

 Score =  204 bits (520), Expect = 5e-51,   Method: Composition-based stats.
 Identities = 60/494 (12%), Positives = 128/494 (25%), Gaps = 43/494 (8%)

Query: 66  VAIRSEAADAGIAQAIMQQLEEALKQLAQG--SGSSQALTQVRRWDSACQKLPDANLALI 123
           VA+       G     +               +     +  +  +       P  +LA++
Sbjct: 13  VAVVGATDREGAVGRAITANLRDRFDGEVVPINPGRDEVLGLECYSDVSSAPP-IDLAVV 71

Query: 124 SVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDCG 176
            V  +   +  N   +     ++        +     + E +L+  A E  L V+GP+  
Sbjct: 72  VVPPDAVIDALNDLGEAGTRNVVVITAGFSETGGEGADRERRLREVAEEYDLNVVGPNSL 131

Query: 177 TSMIAGTPLAFANVMP---EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
             M   + +          EG+I  +  SG  I  +         G    + LG + +  
Sbjct: 132 GVMATPSGMNATFGPEHALEGSISFMSQSGAFITAVLDWANEQEIGFQDVVSLGNKAV-- 189

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAV 293
               +     +     D  ++V+    +   +               P V +  G T A 
Sbjct: 190 ----LDETDFVREWGDDPDTDVIIGYLEDIDDGQEFIEAAREVTDDTPIVLVKSGRTDAG 245

Query: 294 ARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGH 353
           A+  +    +           L +    R         +   L       ++   ++   
Sbjct: 246 AQAASSHTGAIAGSERAYEAGLEQAGVLRARSVQELFDYARALAGLPEPESDGVAVVTNA 305

Query: 354 LGV-------EADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI---DPTLRNQLIAD 403
            G          D T +     D    ++ +   D   V  P   I   D     + +  
Sbjct: 306 GGPGVLTTDAVGDSTLEMAGFTDETIDRLSEAMPDEANVYNPIDAIGDADVDRFGEALEI 365

Query: 404 LGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQC 463
               P V   ++        + D          +    +L+      +  + G       
Sbjct: 366 ALEDPNVGSAVVVAAPTAVLSYD-------ELAETVIDKLEAHDTPVVTCLMGGG----R 414

Query: 464 RSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQ---QHTPSLLENVAVINIGLRS 520
                 TL ++GI        A     AL        +   +     ++      I  R+
Sbjct: 415 ARDAEETLRESGIPNYFDPSRAVSGLDALARFRDIRERTVGEPERFDVDRKRAHEILERA 474

Query: 521 FALELQSASKPVVH 534
              +        + 
Sbjct: 475 RRRDDNRLGVESME 488


>UniRef50_B2T9W3 GCN5-related N-acetyltransferase n=1 Tax=Burkholderia phytofirmans
           PsJN RepID=B2T9W3_BURPP
          Length = 834

 Score =  204 bits (518), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 73/465 (15%), Positives = 121/465 (26%), Gaps = 52/465 (11%)

Query: 66  VAIRSEAADAGIAQAIMQ-QLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +   G    ++  ++ +          +   + L        A        +AL
Sbjct: 15  VAVIGASERPGSTGEMVWTRVLDGGFDGPLWPVNPKYETLGGHAVIHDAGDLPEAPTVAL 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTL-EDEIQLKTR---AREKGLLVMGPDCGTS 178
           I         + ++         +    V   ED + L+     AR   L ++GP     
Sbjct: 75  ICTPPATWPGIIHKLGGLGTRAAIIVGEVRCDEDRLALRHALSAARPNLLRIVGPGSLGV 134

Query: 179 MIAGTPL---AFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREV 235
           +         A +  +  G +  +  S      +       G G +HA+ LGG       
Sbjct: 135 VSPALRAHLGAPSCTVKAGGVAWVSQSNALTNAVLGWAHARGLGFSHAVALGGE------ 188

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA--- 292
             + A   L+ L++D  +  +         A +        A  KP +AL  G       
Sbjct: 189 ADVDAGDVLDYLASDPGTRAILLELDSVRAARKFMSAARAAARNKPVLALRSGRADPADA 248

Query: 293 ----VARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAG 348
                 R   +    +LD+       L  V                GL    TLA +A  
Sbjct: 249 LYTAAFRRAGMVRVDALDDLLDEIETL-GVGRVAAGATATLITSDRGLA---TLACDAFA 304

Query: 349 LLAGHLGVEADDTHQHG--MMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGA 406
                L    D+        +  A     ++LGDD            P      +  L  
Sbjct: 305 AAGDTLAPWPDEASDALKQSLPYAVGGNPLELGDDA----------RPEHFGTALKLLAE 354

Query: 407 KPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQ 466
                      V+       P   +  A                   V    RD      
Sbjct: 355 HRSTGTA---FVVHASTHGAPVGEVAQALIANQRYAYRGLLACFFGGVDAATRD------ 405

Query: 467 QIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA-QQHTPSLLEN 510
               L   GI V ++        A L+           TP  L  
Sbjct: 406 ---ALHAQGIPVHTTPQRLARAFARLVDYRMGRELLMQTPEGLPA 447


>UniRef50_Q0S4P1 Probable acid--CoA ligase n=2 Tax=Rhodococcus RepID=Q0S4P1_RHOSR
          Length = 687

 Score =  204 bits (518), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 78/515 (15%), Positives = 154/515 (29%), Gaps = 49/515 (9%)

Query: 66  VAIRSEAADAGIAQ---AIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +AD        A    + E  +++   +  +  L +     +        +L  
Sbjct: 21  VAVVGASADPAKWGYWLASGALMGEHRRRVHLVNRRTDTLLEHPCHPNLSALPEVPDLVA 80

Query: 123 ISVAGEYAAELANQALDRNLNVMM-FSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           + V   + +++ ++AL   +   +  +  V    E +L  R R  G  ++G +      +
Sbjct: 81  LCVPAPFVSDVVDEALTLGVRGFLGVTAGVP--GEAELAARIRSAGARLVGTNSLGIYDS 138

Query: 182 GTPLAFA-NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA 240
            T L+ A      G + +I  SG    EL +  A  G G++  + +G +        ++A
Sbjct: 139 ATDLSLAWGRFTPGPLAIISQSGQLGSELAALGARHGVGVSRFVSIGNQ------SDVTA 192

Query: 241 LTALEMLSADEKSEVLAFVSKPPAEAV-RLKIVNAMKATGKPTVALFLGYTPAVARDENV 299
              L  L   + + V+A   +  ++     + + A++ TG+PT+ L +G + A  R    
Sbjct: 193 AELLAELGGHDPTRVIALYLESFSDGESLFRTLRALRDTGRPTLLLTVGASAASTRLARS 252

Query: 300 WFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLG---- 355
              S       +          R +             +    A     ++    G    
Sbjct: 253 HTGSLTSALDVVDAACRAAGVLRVSSPDELITVARAFLSTTVPAGNRVAIVGDSGGQCAI 312

Query: 356 ----------------VEADDTHQHGMMLDADSHQIIDL-GDDFYTVGRPHPMIDPTLRN 398
                               ++    +   A S+  +DL G     +G    ++   LR 
Sbjct: 313 AADVTSASALTVPDFSPALAESVALQLPAGAASNNPVDLAGAGEQDLGSYASVVGRLLR- 371

Query: 399 QLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTE 458
                  A     V+L      +   A   A   +A  +             +      E
Sbjct: 372 -------ADESDAVVLTGYFGCYARDAPTLAEHEAAVAERIGRASAETGKPVVVHTMAPE 424

Query: 459 RDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGL 518
                 S     L   G+ V  ++  A    + L     P    H  S       +  G 
Sbjct: 425 ------SSTAQALWRHGVPVFDTVDSAVRALSGLSRLRPPQPSNHALSEPVPRDGLRPGY 478

Query: 519 RSFALELQSASKPVVHYQWSPVAGGNKKLARLLER 553
            +    L                    +LA  L  
Sbjct: 479 WAARELLTELGVAFPDGGVVHTHEEAVELAGRLRA 513


>UniRef50_B0SVW7 CoA-binding domain protein n=2 Tax=cellular organisms
           RepID=B0SVW7_CAUSK
          Length = 893

 Score =  203 bits (515), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 65/455 (14%), Positives = 132/455 (29%), Gaps = 31/455 (6%)

Query: 66  VAIRSEAADAGIAQAIM-QQLEEALKQLAQGSGSSQALTQVRRW--DSACQKLPDANLAL 122
           VA+   +   G    ++ + L            + +AL+        +         LA+
Sbjct: 15  VAVIGGSDRPGSVGQVVVENLLSGGFAGPIYLVNPRALSVAGATWSATIADLPQSPELAV 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-SDNVTLEDEIQ--LKTRAREKGLLVMGPDCGTSM 179
           ++V      ++        + V +  S  +T  + ++  +   A+  GL ++GP+    +
Sbjct: 75  VAVPAATVPQVIADLGAAGVKVAVILSAGLTEANGLRQAMLDAAKPFGLRIVGPNGLGLL 134

Query: 180 IAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVG 236
                L  +        G + +I  SG  +  L         G +  + +G      ++ 
Sbjct: 135 APHARLNASFARGAPTPGGLALISQSGALVSGLIDWANTRQLGFSGIVSVG------DMA 188

Query: 237 GISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARD 296
            +     +++ +AD  ++ +    +    A +           KP +AL  G  PA  + 
Sbjct: 189 EVDLGDLIDLFAADPHTDAILLYVEGVTNAAKFMSAARAAVRIKPVIALKAGRNPASGKA 248

Query: 297 ENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAG---- 352
                 +        AC   R    +             L  G TLA E   ++      
Sbjct: 249 VRSHTGALAGAYDVHACAFERAGIVQVETLTDLFDAAAVLRVGRTLAGERLAIVTNGGGA 308

Query: 353 ---HLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID---PTLRNQLIADLGA 406
               L   A        +      ++       ++ G P  ++           +  + +
Sbjct: 309 GILALDAMASSGGVLAELGPETLERLNTALPAGWSRGNPVDLVGDAPAERYRVALDAVLS 368

Query: 407 KPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQ 466
              V  +L  V+    A A P            AAR        IA   G          
Sbjct: 369 DAGVDAVL--VMNCPTALAQPGDIARGVAASVVAARGRGVRKPVIACWLGDANQ----DA 422

Query: 467 QIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQ 501
               L   G+ +  +   A      L+      A 
Sbjct: 423 AGPILSACGVPMFGAPDAAARAFGHLLAARRAKAS 457


>UniRef50_A6F7C2 Putative uncharacterized protein n=1 Tax=Moritella sp. PE36
           RepID=A6F7C2_9GAMM
          Length = 817

 Score =  202 bits (514), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 71/485 (14%), Positives = 143/485 (29%), Gaps = 45/485 (9%)

Query: 66  VAIRSEAADAGIAQA-IMQQLEEALKQLAQGSGS--SQALTQVRRWDSACQKLPDANLAL 122
           +A+             +++ L  +         S  +  +  +  ++         +L  
Sbjct: 15  IAVIGAKNSTESIGYWVVKNLIASQYDGPIMPISLKANNVCGILAYEKPSDLPIAPDLGA 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKT----RAREKGLLVMGPDCGTS 178
           I     + A++  +  +     ++   +   E            A +  + V+GP     
Sbjct: 75  ICTPIRFVAKIVKELGEVGCKAVILFSDEPYEGNADTWEKIGLIAAKYNIRVLGPSSLGV 134

Query: 179 MIAGTPLA--FANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREV 235
           +     L    A+V P  G++ VI  S      +       G G +  I +G R      
Sbjct: 135 LNPRLKLNVSLAHVAPPAGDVAVISQSAAFATSMIDWAETRGVGFSCFISIGTR------ 188

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFL-----GYT 290
             ++    ++ LS D  ++ +A       +  R        A  KP V +       G T
Sbjct: 189 IDVNFADLIDYLSRDRFTKSIALYVDNIIDTRRFMSAARAAAFKKPIVVVRSSSNIGGAT 248

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARRNAIAP----------VSSGFICGLYTGG 340
             +    N    ++   AA     + RV      ++           V    +  +  GG
Sbjct: 249 ALLQDRRNKISYNTAYTAAFQRSGMLRVNDTFELLSAIKTIATVKRSVRGDKMLIISNGG 308

Query: 341 TLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQL 400
           + A  A  +L       A+ +++    L       I   +    +G     +D    +++
Sbjct: 309 SPAYMAIDVLIKSGCKLAELSYETEQKLLKALPGKITSMNPINILG----GVDAEAYSKV 364

Query: 401 IADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERD 460
           I  +    Q   LL   +I      +                    P+    +  G    
Sbjct: 365 IDIVLEDAQYDALL---IIHAPQVTEECHITAEKLIPQLVKNNKKGPI-IFTSWMGETSG 420

Query: 461 PQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRS 520
                    TL  AGI    +   A      ++       Q+      E +A +N GL +
Sbjct: 421 ----RIARQTLIKAGIPSYGTPEVAVNAFNYIVKF--RRHQKQLIQTPETLADLNPGLIA 474

Query: 521 FALEL 525
            A  +
Sbjct: 475 DAKIM 479


>UniRef50_Q3JJ59 Acetyltransferase, GNAT family n=65 Tax=Proteobacteria
           RepID=Q3JJ59_BURP1
          Length = 1024

 Score =  202 bits (514), Expect = 3e-50,   Method: Composition-based stats.
 Identities = 65/449 (14%), Positives = 118/449 (26%), Gaps = 51/449 (11%)

Query: 65  CVAIRSEAADAGIAQAIMQQLE---EALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
            VA+   +   G   A++            +   +     L   + +    Q     ++A
Sbjct: 251 AVAVVGASPRPGSVGAMVWACVLDGRFGGAIWPVNPKYGELNGHKVYPYVDQLPSAPSVA 310

Query: 122 LISVAGEYAAELANQALDRNLNVMMFSD----NVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           LI         +  +     +   +               +    A+   L V+GP    
Sbjct: 311 LICTPPATWPGIVRKLGGLGVRAAIIVGETRSGADRAALERALAAAKPYLLRVVGPGSLG 370

Query: 178 SMIAGTPLAF---ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSRE 234
            +       F   A ++  G +  +  S      +       G G +HA+ LGG      
Sbjct: 371 VVSPALGAHFGAPACIVKAGGVAWVSQSNALTNAVLGWAHARGLGFSHAVALGGE----- 425

Query: 235 VGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP--- 291
              + A   L+ L++D ++  +         A +        A  KP +AL  G      
Sbjct: 426 -ADVDAADVLDYLASDAETRAILLELDTVKSARKFMSAARAAARNKPVLALRAGRGDSGD 484

Query: 292 ----AVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAA 347
               A  +   +    +LD+       L    A   +          G+     LA +A 
Sbjct: 485 LLYTAAFQRAGMVRVDALDDLLDEIEALGVGRAAATSGGVTLVTSDRGVAK---LAVDAL 541

Query: 348 GLLAGHLGVEADDTHQHGMMLDADS---HQIIDLGDDFYTVGRPHPMIDPTLRNQLIADL 404
                 L                        + LGDD            P      +  L
Sbjct: 542 AAAGETLAQWPRAAVDEVGGALPAGIVAGNPLLLGDDA----------RPEYFGAALKAL 591

Query: 405 GAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCR 464
              P    +    V+   + + PA  +     ++               V    RD    
Sbjct: 592 AQHPPTGTV---FVVHATSHSAPAVDVARVLIESRKFARRGMLACFFGGVDAATRD---- 644

Query: 465 SQQIATLEDAGIAVVSSLPEATLLAAALI 493
                 L   GI V ++        A L+
Sbjct: 645 -----ALHVHGIPVHTTPQRLARAHARLV 668


>UniRef50_A3TZP8 Putative acetyl-CoA synthetase n=1 Tax=Oceanicola batsensis
           HTCC2597 RepID=A3TZP8_9RHOB
          Length = 463

 Score =  202 bits (514), Expect = 3e-50,   Method: Composition-based stats.
 Identities = 61/453 (13%), Positives = 137/453 (30%), Gaps = 64/453 (14%)

Query: 66  VAIRSEAADAGIAQAIMQQLE---EALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   +   G     +  L        ++   + S   +  ++      +     ++ +
Sbjct: 21  IAVVGASRTKGKLGQAVLALLKSNGYGGKIIPVNPSGGEIEGLQAGRDLEEIDGPIDVVV 80

Query: 123 ISVAGEYAAELANQALDRNLNVMM-FSDNVTL------EDEIQLKTRAREKGLLVMGPDC 175
           ++     A +        N+ V++  +   +       E+E +L+   ++    ++GP+C
Sbjct: 81  LATPVGAALDALETCTRLNVKVVVGVTSGFSEAGDDGHENEERLRKIMQDAPFRLVGPNC 140

Query: 176 GTSMIAGTPLAFA-----NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
              +   + L        N +  G + +I  SG     +  ++   G GI   +  G   
Sbjct: 141 EGVVRPASDLQLTFSPMFNGLRPGPVAMISQSGALAGLMALRLGERGVGINAIVSSGNET 200

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVN-AMKATGKPTVALFLGY 289
                  ++A   L+    D ++ V+    +   +  R       +   GK  VA+  G 
Sbjct: 201 ------DLTAAHLLDYFGNDPQTRVVLCYVEELRDGRRFAEAAQRLTRAGKHVVAVKGGR 254

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLA------ 343
           + A +R       +   +   ++ +       R   +  +   +  L  G   A      
Sbjct: 255 SRAGSRAVQSHTGAMAGDDRVISAVFRETGVIRARESVAAVDAVTALAAGRRPAGNRVCI 314

Query: 344 --------------AEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPH 389
                         AE+AG     L           +         +DL           
Sbjct: 315 ISVTGGLGVEMTDLAESAGFEVPVLDEATQTALSRYVPFYGSVSNPVDLTG--------V 366

Query: 390 PMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLY 449
            + +PT   + +  + A P V + +  +      T  P    + A  +A           
Sbjct: 367 VLANPTYVGRCLEAVAADPGVDIAIAII------TFVPDQQFIEALAEAFDRTD----KP 416

Query: 450 AIATVTGTERDPQCRSQQIATLEDAGIAVVSSL 482
            +   TG+ R           L +  + V  S 
Sbjct: 417 ILIVWTGSARSNASGE----ALRERAVPVYDSP 445


>UniRef50_B8FE80 CoA-binding domain protein n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FE80_DESAA
          Length = 725

 Score =  202 bits (513), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 57/476 (11%), Positives = 125/476 (26%), Gaps = 45/476 (9%)

Query: 62  NDICVAIRSEAADA-GIAQAIMQQLEEALKQLAQGSGSS--QALTQVRRWDSACQKLPDA 118
           N   VA+             +   +     +      +     +   + + +        
Sbjct: 259 NAESVAVVGATKPNISGFAGMFGCMHLFGFKGRLYPINPKLDEIYGHKAYPNLTALPEKV 318

Query: 119 NLALISVAGEYAAELANQALDRNLN-VMMFSDNV-------TLEDEIQLKTRAREKGLLV 170
           +L ++SV  +    +  + +      + +F+           +  + ++K  A E GL V
Sbjct: 319 DLVIVSVPAQVVPGVLRECVATGNKTIHIFTAGFKESGEEEGVRLQKEMKQIAVEGGLRV 378

Query: 171 MGPDCGTSMIAGTPLAF--ANVMPEGNIGVIGASGTGIQELCSQIA-LAGEGITHAIGLG 227
           +GP+C    +    +          G I +I  SG   QE+        G G    +  G
Sbjct: 379 IGPNCMGFYVPNRRMLTWQKASKKSGPIALISQSGGNAQEITHYATGRYGIGFNKVVSYG 438

Query: 228 GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFL 287
                           L+ L+ D+++E++    +      R   +       KP +    
Sbjct: 439 NALTVES------ADFLDYLAGDDETEIITMYLEGLKNGRRFLKLAEETNKKKPILIYKG 492

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIA--------------PVSSGFI 333
           G +   A+  +    +             +                              
Sbjct: 493 GLSETGAQAVSSHTGALAGGPKIWHSFFRQTGCVLVESVEELAEVAMAFHYLPETKGPRT 552

Query: 334 CGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID 393
             L  GG      A   A       D +      L         +  +           D
Sbjct: 553 AVLGYGGGAGVSVADNCAKLNLALPDFSEDLLGKLREIIPPAGTIIRNPID--AMIAYFD 610

Query: 394 PTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAAR--LDNQPLYAI 451
             +  ++   +    ++  +L+ + + +    +     +    +  A            I
Sbjct: 611 FDVMGKIFKLMAESDEIDNVLMSIPLDWLFNKEEGGGYIETLTRYVAEEGVRHLGCKPFI 670

Query: 452 ATVTGTERDPQCRSQQ-----IATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQ 502
           AT    +  P  + +         L DAGI V   +       A +       A+ 
Sbjct: 671 ATW--RQYMPSGKIRSWAPVMEKILLDAGIPVYEGMARGINAMAKVTAYYDFHAKN 724


>UniRef50_Q47QC0 Putative uncharacterized protein n=2 Tax=Nocardiopsaceae
           RepID=Q47QC0_THEFY
          Length = 886

 Score =  201 bits (512), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 75/486 (15%), Positives = 142/486 (29%), Gaps = 30/486 (6%)

Query: 65  CVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRW--DSACQKLPDANLAL 122
            V I        +  AI++ +  +       +    A          S        +LA+
Sbjct: 201 VVVIGGTRRQVSVGNAILRNIRASGFTGRLYAVHPHAAAVADVSAVPSVADLPEVPDLAV 260

Query: 123 ISVAGEYAAELANQALDRNLNV-MMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           +SV  +   ++A    ++ +   ++ + ++  E   +L    R  G+ ++GP+C      
Sbjct: 261 VSVPPDAVLDVARACGEQGVGALVVITADLDTETSQELLAVCRWHGMRLVGPNCFGVASL 320

Query: 182 GTPLAF-----ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVG 236
              +       A     G  G++  SG     L   ++    GI+  +  G +       
Sbjct: 321 SDGVRLQATFAAEAPRPGQAGLVVQSGGIGITLLEHLSRLDVGISSFVSTGNKL------ 374

Query: 237 GISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARD 296
            +S+   L+    D  + +     +      +   +       KP + +  G + A  R 
Sbjct: 375 DVSSNDLLQWWEDDPDTAMAIMHVESFGNPRKFSRIARRLGRRKPILTVVAGRSTAGQRA 434

Query: 297 ENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGV 356
                 +SL  A     L  +             G    L       A         + +
Sbjct: 435 AASHTGASLTPALTTESLFEQAGVVAARSLDELVGTAAFL-------AHQPLPSGPRVAI 487

Query: 357 EADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLD 416
             +      +  DA +   +++ +    V R    + P           A P        
Sbjct: 488 VTNAGGTGVLAADACADVGLEVHELSEEVRRELEELLPA------GAACANPIDTTPAAS 541

Query: 417 VVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIAT--LEDA 474
                      AA+ V A            PL  +AT+ G          Q     L  A
Sbjct: 542 SDQLRACLERLAAAEVDAIIAIMVRTALADPLPVVATMAGGVPVAAVAPHQAEAVTLLSA 601

Query: 475 GIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVH 534
           G   V S  +    AAAL H    A     P+     ++  + +      +Q   K    
Sbjct: 602 GGHSVPSYNDPRAAAAALGHAWRRARWLARPAG-SVPSLRAVAVERARDIVQEFLKRHPE 660

Query: 535 YQWSPV 540
             W P+
Sbjct: 661 GGWLPL 666


>UniRef50_A3TKE9 Putative uncharacterized protein n=1 Tax=Janibacter sp. HTCC2649
           RepID=A3TKE9_9MICO
          Length = 892

 Score =  201 bits (512), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 61/477 (12%), Positives = 140/477 (29%), Gaps = 44/477 (9%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+              ++ L +          + +++ +   + +D+        +LA+
Sbjct: 210 VAVIGAGRSPQSMGHHFLKNLLDGGFTGQAHPVNRNAKKILGRKTYDTIGDVPGPVDLAV 269

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLE--------DEIQLKTRAREKGLLVMGPD 174
           I+V  +   ++ ++    +++ ++       E         + +L  RAR  G+ ++GP+
Sbjct: 270 IAVPADKVLKVVDECAAADVDALLIVSAGFGEGGGEGGDELQSELVRRARGSGMRIVGPN 329

Query: 175 CGTSMIAGTPLAFAN-----VMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
               +     L+        + P+G++G+   SG     + +  A    GI+     G R
Sbjct: 330 SFGLINTDPALSLNASLSPDMPPKGHLGLFAQSGALGIAVLASAARRNLGISSFGSAGNR 389

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
                   +S    ++    D+ +  +    +      +   +       KP + +  G 
Sbjct: 390 ------VDVSGNDFMQYWIDDDDTHAVGLYLESMGNPRKFSRIARNLGRIKPVIVVQSGV 443

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGL 349
           +   A         +    A  A +L +    R +           +      A     +
Sbjct: 444 SAYGA-PPGHRVRRTKVRPAVFAAMLRQAGCIRVSNVHQMFDVAQLVVHQPLPAGRRVAI 502

Query: 350 LAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQ 409
           +     + A             +H  I+L  +                 + +      P 
Sbjct: 503 VGNSSALGALSAGAVAGRGLKVTHGPINLPSEATA----------EQFREALTKAFEDPD 552

Query: 410 VRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIA 469
           V  +L   +    A             +A  +         +AT  G             
Sbjct: 553 VDSVLTCFIPPIVAHD-------EEVTEAVRSAARKSDKTCVATFLGMRGVHSSTHMDEG 605

Query: 470 TLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQ 526
                 I + +   +A   A AL      A  ++    +  VA + I  R     +Q
Sbjct: 606 GTTGQAIPIYAMPEDA---AYALAKATKYAEWRNKDHGVP-VAPVGINRRVAEDVVQ 658


>UniRef50_A7IQG8 CoA-binding domain protein n=1 Tax=Xanthobacter autotrophicus Py2
           RepID=A7IQG8_XANP2
          Length = 727

 Score =  201 bits (510), Expect = 8e-50,   Method: Composition-based stats.
 Identities = 74/525 (14%), Positives = 144/525 (27%), Gaps = 60/525 (11%)

Query: 66  VAIRSEAADAGIAQ-----AIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANL 120
           VA+   +A  G         ++        ++         +     + +        +L
Sbjct: 34  VALVGASATPGKLGYLFMQNLIAPQSGFGGEVIAVHPKLTEILDRPAYANLSAVPGGVDL 93

Query: 121 ALISVAGEYAAELANQALDRNLNV-MMFSDNVTL------EDEIQLKTRAREKGLLVMGP 173
           A+I         +        + V ++ S             E ++   AR  G+ ++GP
Sbjct: 94  AVIVAPPGEIPAIMVDCAAARVPVAIIISGGFAETGDAGRMLEQRIVATARSGGVRLIGP 153

Query: 174 DCGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
           +C   + A   L  +    +  +G I +   SG       +Q      G +  +  G + 
Sbjct: 154 NCFGVISASAGLNASLGIGMPAQGGIALYTQSGAYGMAAFTQSQEELIGFSRVVACGNK- 212

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
                  +     L+    D ++ V+A + +   +  R        A  KP V L  G +
Sbjct: 213 -----VDLDETDVLQAFGEDPETRVIAMLLESIGDGRRFFEAAREIAQRKPIVILKTGRS 267

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTA--------------RRNAIAPVSSGFICGL 336
            A  R      A+   ++A     L +                   +   P++   I  +
Sbjct: 268 EAGRRAAASHTAALATDSAITLSALRQAGIRVVDDGLTLLDLAAALDRQPPLAGRRIAII 327

Query: 337 YTGGTLAAEAAGLL------AGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHP 390
              G    E A LL         L        +  +     +   ID+  +         
Sbjct: 328 SNSGGTGVEIADLLESRGLQVPKLSEPLQAAIRPVLPAYGSAANPIDVTTE--------W 379

Query: 391 MIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYA 450
              P +    +A L    +   ++    +    +A  +        +  AAR        
Sbjct: 380 RRFPEMYGSSLAALIDSDETDAVV---PVLLQRSALMSEVTDRVIAEVAAARARGSRKPV 436

Query: 451 IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATL--LAAALIHPLSPAAQQHTPSLL 508
                G++            L  AGI   +           +A      P      P   
Sbjct: 437 HVCWVGSDA----AEDNRRRLLTAGIPCHAWPARTAQVLALSAPAGRSQPRGATARPVAR 492

Query: 509 ENVAVINIGLRS--FALELQSASKPVVHYQWSPVAGGNKKLARLL 551
             + V    L S      +  A  PV  ++ +         A  L
Sbjct: 493 PPIGVDGGWLSSDLAFSLIADAGLPVAPWRIAGSRAEAIAAAETL 537


>UniRef50_A9A2G6 CoA-binding domain protein n=6 Tax=Thaumarchaeota
           RepID=A9A2G6_NITMS
          Length = 705

 Score =  200 bits (509), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 70/508 (13%), Positives = 135/508 (26%), Gaps = 72/508 (14%)

Query: 30  VDDVSVMMGTPANK-ALLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQ-AIMQQLEE 87
           V D  +++     K ++        D     TP    VA+   +A  G    +I+  L  
Sbjct: 223 VVDAKIILNKEKKKNSISKAKPSITDMETFFTPKS--VALVGASASPGKIGNSILDSLVN 280

Query: 88  ALKQLAQGSGSSQA--LTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVM 145
              +      + +A  +   + + S        +L ++SV       +      + ++ +
Sbjct: 281 YDFKGKVYPINPKADKIFGQKCYPSVADIPGKVDLVVVSVDLSMTPPVLEDCAKKGVHSV 340

Query: 146 MFSDNVTLED-------EIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPE----- 193
           +       E        E ++   +++  + ++GP+C     A   L  A    E     
Sbjct: 341 VIVSGGGKELGGERAAYEAEVARLSKKHKIRIIGPNCIGMFNAANRLDCAFQGQERMVRS 400

Query: 194 --GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADE 251
             G +     SGT    +         G++  I  G R        +     +   + D 
Sbjct: 401 KLGPVAFFSQSGTMGISMLESADT--FGLSKMISFGNR------SDVDEADMIWYAANDP 452

Query: 252 KSEVLAFVSKPPAEAVRLKIVNAM--KATGKPTVALFLGYTPAVARDENVWFASSLDEAA 309
           +++V+    +   +  +   V     K   KP V    G T A A+       S     A
Sbjct: 453 QTKVIGLYVEGFGDGRKFINVAKRVMKEKKKPIVIWKSGRTAAGAKQAASHTGSLGGSNA 512

Query: 310 RLACLLSRVTARRNAIAPVSSGFICGLY--------------------TGGTLAAEAAGL 349
            +     +            +G +  L                      GG    E  GL
Sbjct: 513 IIMGAFKQAGIISVDSYQELAGVLKALAWQPAAKGNKVAMTSNGAGPMIGGIDQLEKFGL 572

Query: 350 LAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQ 409
             G L  +     +         H       +   VG      D      +I     +  
Sbjct: 573 AIGKLSPKLLKKMKSRFPPAVPIHN-----GNPADVGGGATADD---YQFVIQQFMDEKN 624

Query: 410 VRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIA 469
           + + +   V       DP            A          +    G         + I 
Sbjct: 625 IDIAMPWFVFQ----DDPLEET---IVDHLAGFQKKAKKPLLCGGNGGPYT----EKMIK 673

Query: 470 TLEDAGIAVV---SSLPEATLLAAALIH 494
            +E   + V     +   A         
Sbjct: 674 LIEKHNVPVYQDLRTWVAAASALHQWGK 701


>UniRef50_Q7WC02 Putative acyl-CoA synthetase n=2 Tax=Bordetella RepID=Q7WC02_BORPA
          Length = 710

 Score =  200 bits (508), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 79/536 (14%), Positives = 149/536 (27%), Gaps = 64/536 (11%)

Query: 36  MMGTPANKALLDT-TGFWHDDFNNATPNDICVAIRSEAADA-GIAQAIMQQLEEALKQLA 93
           MMG  A   L++   G          P   CVA+   + D       I+  L     +  
Sbjct: 1   MMGGSAVMTLIEEQAGRSASVVELMNP--ACVAVVGASEDRRKFGGRILHLLNNQGFRGR 58

Query: 94  --QGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDN 150
               +     +   + +          +L ++++  +   +  +   D     V++ +  
Sbjct: 59  ILPVNPVRAEILGHQAYRCIMDLPQAPDLVILAIPRDLVVQAVSDCGDIGAKGVIVVASG 118

Query: 151 VTL------EDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVM-------PEGNIG 197
            +         E QL   AREK + ++GP+C   +      + A  +         G+IG
Sbjct: 119 FSESGDEGARLEQQLLAVAREKAVRIIGPNCVGVVSPAHGFSLATTVSLVDRAPLPGHIG 178

Query: 198 VIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLA 257
           +I  SG  +  +  +      G +H I +G +        +     ++ +  D  + V+ 
Sbjct: 179 LISQSGAVMGTMIDRGISQNVGFSHCISVGNQ------ADVDFCDFVDFMIDDPGTHVIC 232

Query: 258 FVSKPPAEAVRLKIVN-AMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLS 316
              +               +A  KP + +  G T A A       AS     A L  +  
Sbjct: 233 TYVEGIKRPDLFLRAAGRAQAASKPWLLMKSGRTEAGAASAFSHTASLASNQAILDGVCR 292

Query: 317 RVTARRNAIAP--------------VSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTH 362
           +    +                   +    +  L   G     AA  L+      A  + 
Sbjct: 293 QFGILQVDDVEGMLVAASGWNKYRDMRVRSVAVLSPSGGGCTIAADRLSDIGVPLARFSD 352

Query: 363 QHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFG 422
           +    L       +    +   +G  +          +        Q  ++L  V     
Sbjct: 353 RATAALAPLFDGPVR---NPVDIGAANDGAAMGYVETIHRAALQDEQADLVLSVV----- 404

Query: 423 ATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQ-QIATLEDAGIAVVSS 481
                 A +++   K             +A V      P   ++     L  AG+    S
Sbjct: 405 ----TNAPVLTEVGKMIGDAARAVDQPLLAVVI-----PGGYAEGAREQLAAAGVLCTDS 455

Query: 482 LPEATLLAAALIHPLSPAAQQH--TPSLLENVAVINIG---LRSFALELQSASKPV 532
           L  A     A        A      P  L     +  G          L      V
Sbjct: 456 LDAAMRAIGAWHAWARRPAASSAVRPQGLPVPEPVGAGRLDEAGVKRLLGRYGIRV 511


>UniRef50_C9M5R5 CoA-binding protein n=1 Tax=Jonquetella anthropi E3_33 E1
           RepID=C9M5R5_9BACT
          Length = 704

 Score =  199 bits (507), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 64/507 (12%), Positives = 143/507 (28%), Gaps = 53/507 (10%)

Query: 66  VAIRSEAAD-AGIAQAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +A+   +    ++ ++           +     +   + + +       A++A+
Sbjct: 17  VAVVGASANLDSLTGRTIKVMKRFGFSGDLFPVNPKYDQVGGYQCYKNLADIPGSADVAV 76

Query: 123 ISVAGEYAAELANQALDRNL-NVMMFSDNVTL----EDEIQLKTRAREKGLLVMGPDCGT 177
           ISV       +    + + + N +++S         + + Q+ + AR   + ++GP+C  
Sbjct: 77  ISVKANIVPSVLETCIAKGIPNAVIYSSGFAETGNKKLQEQILSIARSGKIRILGPNCQG 136

Query: 178 SMIAG--TPLAFANV------MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
            +     TPL F            G++  +  SG             G    + +  G +
Sbjct: 137 LLNLAEKTPLTFTGALLDVDPPKAGHVAFVSQSGAFGFSSFGVGLDHGVNYRYVVTTGNQ 196

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNA-MKATGKPTVALFLG 288
                   + A+     +  D +  +L    +   +  R   +    +        L  G
Sbjct: 197 ------ADVDAVECASYVICDPQVRLLMMYLEGIGDGQRFLQMVKDARERNIAVAVLKAG 250

Query: 289 YTPAVARDENVWFASSLDEAARLACLLSRVTAR-----RNAIAPVSSGFICGLYTGGTLA 343
            +P   +      A+   + A    +  +          +              TG  +A
Sbjct: 251 RSPISQKAAQSHTAALTGDEAVWDAIFDQYGIIPMEDMDDITGIGQMFGARQRATGDRVA 310

Query: 344 AEAAGLLAGHLGVEADDTHQH-GMMLDADSHQIIDLGDDFYTVGRPHPMID--------P 394
                   G   V AD        + +  +     + ++  + G P   +D        P
Sbjct: 311 I--LTTSGGAGIVMADSLTDLKIQVPELSADTQKKMAENIPSFGSPRNPVDMTIQVSETP 368

Query: 395 TLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATV 454
               Q++      P V +++  + +  G   D                            
Sbjct: 369 EKFQQVLKTAMDDPDVHMVVTALSMVIGKAGD-------VMADELIRNYQTAEKPQAVVW 421

Query: 455 TGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVI 514
                D       I  L+DAGI +  S  +      A+++     A      +     + 
Sbjct: 422 M---IDQAHGGSFIQRLKDAGIPIFQSFRQCARSLRAMVNWHQLRALPKDEPVTGTPILQ 478

Query: 515 N----IGLRSFALELQSASKPVVHYQW 537
           N    +        L     PV     
Sbjct: 479 NYPPLMSEYDAKCLLSKYGIPVTREAL 505


>UniRef50_A3TZG5 Putative pimeloyl-CoA synthetase n=1 Tax=Oceanicola batsensis
           HTCC2597 RepID=A3TZG5_9RHOB
          Length = 715

 Score =  198 bits (503), Expect = 5e-49,   Method: Composition-based stats.
 Identities = 67/490 (13%), Positives = 136/490 (27%), Gaps = 70/490 (14%)

Query: 62  NDICVAIRSEAAD-AGIAQAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDA 118
           N   +A+   + D       ++  L            +   + +  +    S        
Sbjct: 26  NARSIAVVGASDDLRKPGGRVVNALLHNSFPGKVYPVNPGRETIQGLECHPSLAAIAEPV 85

Query: 119 NLALISVAGEYAAELANQALDRNLNV-MMFSDNVT------LEDEIQLKTRAREKGLLVM 171
           +L ++SV  +          D  +   ++F+   +      +  + ++    ++ G+ ++
Sbjct: 86  DLVILSVPADDVPNQLRMGCDCGVGGFIVFASGFSEIGPEGVARQAEISKIVQDAGIPMI 145

Query: 172 GPDCGTSMIAGTPLAFANVM-------PEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           GP+C   M     +  ++ +       P GN G I  SG            AG G++  I
Sbjct: 146 GPNCLGIMNGNHKMLASSTVVMGGRKLPGGNYGFISQSGALGTYWLDMSMKAGLGVSSWI 205

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMK-ATGKPTV 283
             G          +     L+ L  D+++EV+    +   +    +          KP +
Sbjct: 206 STGNE------ADVDLAACLDYLVEDDETEVIGLYIEGVRDGAAFRAAARKAFERRKPVL 259

Query: 284 ALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYT----- 338
            L  G +   A        +   E      +  +    R+      +     L T     
Sbjct: 260 VLKSGSSRQGATAAASHTGALAGEDEAYDAVFRQYNICRSDSLTDMANKAEILLTQPRSA 319

Query: 339 ------------GGTLAAEAAGLLA---GHLGVEADDTHQHGMMLDADSHQIIDLGDDFY 383
                        G L  +AA            E        +   A     IDL     
Sbjct: 320 GQRVVVISVSGGAGVLMTDAAVAEGLDVPDFSPETKARLVEILPGFASPQNPIDLTAQIV 379

Query: 384 TVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARL 443
                      T+  +++  +        +LL +    G  +  A  L  A         
Sbjct: 380 MH--------KTMLREVLQIISDGSGFDGVLLFM----GGLSQIAEELADALVSEL---- 423

Query: 444 DNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQH 503
             + +    T            + +  + D G+ V   + +A    AA        A   
Sbjct: 424 -PRDMPCALTWQAAP------EETVQHVRDRGVPVYGEIGDAARALAAQFRMG---AGWD 473

Query: 504 TPSLLENVAV 513
            P   E   +
Sbjct: 474 RPVPPEAPTI 483


>UniRef50_C2APW0 Acyl-CoA synthetase (NDP forming) n=1 Tax=Tsukamurella
           paurometabola DSM 20162 RepID=C2APW0_TSUPA
          Length = 727

 Score =  198 bits (502), Expect = 6e-49,   Method: Composition-based stats.
 Identities = 88/485 (18%), Positives = 154/485 (31%), Gaps = 54/485 (11%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALK--QLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   + D        ++ L+ +     +   +  +  +  +    S  +   D ++AL
Sbjct: 29  IAVVGASTDPAKRGYQSIRALQRSGYRHPIHPVNPRATRILGLDVAPSVEELPRDIDVAL 88

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDC 175
           I++ G    +         +   +        S +     E +L     E G+ V+GP+ 
Sbjct: 89  IALPGPLVPDALRACAGVGIRSAVVLANGFKESGHAGAALEAELAAVIAETGIRVIGPNT 148

Query: 176 GTSMIAGTPLAFANV--MPEGNIGVIGASGTGIQELCSQIALA-GEGITHAIGLGGRDLS 232
              + A T      +  +P+G I V+  SG  +  L +      G G     GLG +   
Sbjct: 149 SGIINASTGANLVGLLDIPQGPISVVTQSGNMLLSLVNDDRALQGPGFHVYAGLGNQ--- 205

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                +S    L  ++ D+++  +A  ++   +     +  A      P V +  G +  
Sbjct: 206 ---VDVSYADCLTAMAEDDQTGAIAVHAEGLIDGRGFLVAAARAVADTPVVMVRGGRSEI 262

Query: 293 VARDENVWFASSLDEAARLACLLSRVTA---------------RRNAIAPVSSGFICGLY 337
             R       S     A    +L +                      +   +   I  L 
Sbjct: 263 GRRTALSHTGSVAGSDAVATAVLRQAGVELVDRSDELAVVAGALAATVPVQAGRSIAILA 322

Query: 338 TGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPM-----I 392
            GG  A  AA  LA      A+ + Q         H++  L  D   V  P  +      
Sbjct: 323 DGGGHATLAADALAELGVSLANTSEQ-------TQHRLRQLLGDAAAVANPVDVAGATDA 375

Query: 393 DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLD---NQPLY 449
           DPT+       L A P V ++L+  + G G      A L +A Q       D      + 
Sbjct: 376 DPTVFVDAARILMADPAVGLVLIVGMFG-GYHLRFDAGLHAAEQSTADRLADLSRAARIP 434

Query: 450 AIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLE 509
            +         P       A L   G  VV+S+  A  + AAL             S L 
Sbjct: 435 LVVQSCYAAA-PNPVH---ARLRTEGFTVVNSIDHAARIVAALTRRGDRLGTAGLRSDLA 490

Query: 510 NVAVI 514
               I
Sbjct: 491 LPTPI 495


>UniRef50_Q7WM17 Putative uncharacterized protein n=1 Tax=Bordetella bronchiseptica
           RepID=Q7WM17_BORBR
          Length = 498

 Score =  198 bits (502), Expect = 6e-49,   Method: Composition-based stats.
 Identities = 73/460 (15%), Positives = 137/460 (29%), Gaps = 42/460 (9%)

Query: 66  VAIRSEAADA-GIAQAIMQQLEEALKQLAQGS--GSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   +A         ++ L              S+  +  +  + S        + A 
Sbjct: 16  IAVVGASASTVSGGNRFIRNLRAFGYAGPIYPVHPSAGEIEGLPVFASLEALPETVDYAY 75

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDE-----IQLKTRAREKGLLVMGPDCGT 177
           ++ A E    +      +     + S       E       L   AR+  + V+GP+C  
Sbjct: 76  VATAAERVPGVIRSGRGKVRVAQVMSSGFGETQEGDALQRDLLAAARDANVRVVGPNCLG 135

Query: 178 SMIAGTPLAFANVMP--EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREV 235
                  ++F   +    G++GV+  SG    ++  +    G   +  + +G        
Sbjct: 136 VYSPRARVSFTRRVTDEAGHVGVVCQSGGLGTDIIRRGQQRGLRFSGLVTIGN------A 189

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVAR 295
             +SA   LE   ADE++ V+    +   +  RL  V       KP V L  G T    R
Sbjct: 190 VDVSASELLEYFLADEQTRVIGMYLESARDGRRLFEVLRQAGCRKPVVLLKGGGTAQGRR 249

Query: 296 DENVWFASSLDEAARLACLLSRVTARR------------------NAIAPVSSGFICGLY 337
             +    +        A L  +                           P  +  + G  
Sbjct: 250 AASSHTGALAGSEQAWAALGKQTGMPIVDTLDEFLDVLLLCQCLLPRSQPTRTVALFG-N 308

Query: 338 TGGT--LAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPT 395
            GGT  L  +A G     +   A DT      L   +   +   +            +  
Sbjct: 309 GGGTSVLGTDACGRAGFAVPPFAADTLAALEALKLPAGSSV--LNPVDVPAGALQQNEGR 366

Query: 396 LRNQLIADLGAKPQVRVLLLD---VVIGFGATADPAASLVSAWQKACAARLDNQPLYAIA 452
               ++  L     +  +++     VI      D   ++++A  +A         L  + 
Sbjct: 367 AATDIVRILAQDDSIDAVIIHANMTVITDFQHVDMLKNIIAAVTQARQHGRGVAHLILVL 426

Query: 453 TVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAAL 492
              G     + +         AGI V + + EA    A L
Sbjct: 427 RSDGDAEIEERKRGYRRDSVQAGIPVFNEIAEAAKALACL 466


>UniRef50_C8X6G7 GCN5-related N-acetyltransferase n=1 Tax=Nakamurella multipartita
           DSM 44233 RepID=C8X6G7_NAKMY
          Length = 926

 Score =  198 bits (502), Expect = 7e-49,   Method: Composition-based stats.
 Identities = 64/470 (13%), Positives = 138/470 (29%), Gaps = 38/470 (8%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+     D       +++ L +     +    +    A+  V    S  Q     +LA+
Sbjct: 234 VAVIGAGQDPSAVGHQVLRNLIDGGFTGSLVAVNPHHDAVLGVPCVPSPAQLPCGIDLAI 293

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDC 175
           +++      ++      R+   M+        +       + ++   AR+ G+ ++GP+C
Sbjct: 294 VAIPAAGVLDVVRGCGARHTRAMVILTAGFGEAGAAGRSRQDEILAAARQDGMRLVGPNC 353

Query: 176 GTSMIAGTPLAFANV-----MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
              +     +          +P G +G++  SG     +      AG G+   + +G R 
Sbjct: 354 LGLINTDPAVRLNATFTDLPVPAGPLGLVSQSGALGIGVLDAAGRAGPGVAQFVSIGNR- 412

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
                  +S+   L   + +++  V+A   +          V    A  KP +A+  G +
Sbjct: 413 -----ADVSSNDLLAAWADEDRIRVVALYLESVGNPRTFARVARRVADRKPVIAIKSGRS 467

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLL 350
            A  R      A++      +  L  +    R             L      +     ++
Sbjct: 468 AAGRRAGRSHTAAAATGDVVIDALFRQAGVLRVDTMEQMLDAARVLCDQPVPSGCRLAVV 527

Query: 351 AGHLGVE-------ADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID---PTLRNQL 400
               G +       +    +   +       +  +  D  +   P  +     P      
Sbjct: 528 GNSGGPQILAADAASAAGLEVVELAPGTRRALRQVVPDAASADNPVDLGSAATPVQVGDA 587

Query: 401 IADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERD 460
           ++ L A  +V  +L  V          A + + A     AA            V  T   
Sbjct: 588 LSVLLAADEVDAILAVV-------TRTAVTDLPAVLDRIAAAAGGDKPVVACCVGETAES 640

Query: 461 PQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLEN 510
            +        L   G    ++   A       I           P+ ++ 
Sbjct: 641 VRVPGAADRRLPVFGFPEPAAAALAVAARYGRIRSADGPGHPARPAGIDR 690


>UniRef50_Q89PN4 Blr3446 protein n=1 Tax=Bradyrhizobium japonicum RepID=Q89PN4_BRAJA
          Length = 707

 Score =  198 bits (502), Expect = 7e-49,   Method: Composition-based stats.
 Identities = 83/515 (16%), Positives = 161/515 (31%), Gaps = 66/515 (12%)

Query: 66  VAIRSEAADAGIAQAIMQQLE---EALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +AI   + +A         L        ++   +  +  +  ++ + S  +     +LA+
Sbjct: 16  IAIIGASQEATKIGGRPVDLLRRHGYAGRIYPVNPKAVTVQGLKAYASVAEVPEAPDLAI 75

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEI------QLKTRAREKGLLVMGPDC 175
           I+V  E A E   Q   R +  V++FS       E       +L+  AR  G+ ++GP+C
Sbjct: 76  IAVDAERAGEAVEQCAARGVRSVVVFSSGFAELGEQGRAMQDRLRLAARNSGMRLLGPNC 135

Query: 176 GTSM------IAGTPLAFANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
             ++      IA   +   + MP  G++G++  SG          +  G G++  I  G 
Sbjct: 136 LGAVSVAEKSIATFSIVLEHSMPAAGSLGIVSQSGNLGSYTMRLASERGVGVSRFITTGN 195

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEA-VRLKIVNAMKATGKPTVALFL 287
                    +     +  ++ D  ++V+    +   +A   +  +   +  GKP +A+ +
Sbjct: 196 E------CDVDIADGIAWMARDPATKVILCCLEACRDAGRLISALEEARDAGKPVIAMKI 249

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAP-----------------VSS 330
           G + A          +     A    L +R  A R                         
Sbjct: 250 GTSAAGQAAAASHTGAMAGSDAVFDALFARCGAVRVRSIDELIDLGHAASILLPDRLPKG 309

Query: 331 GFICGLYTG---GTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGR 387
             I  L      G L A+AA  +   L     +T +  + L   +     +        R
Sbjct: 310 PGIAILTASGGFGVLLADAAQSVGLTLPELGQETQRQILELVPFASARNPVDATAQMSSR 369

Query: 388 PHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQP 447
                 P L  +++  + A  +   ++L +           +  +   +   A       
Sbjct: 370 ------PDLLEKIMTAVVADDRADTVILPLPFSLHL-PRLRSIYMDTLRNIRAQFPQ--- 419

Query: 448 LYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLS-PAAQQHTPS 506
              +  V G E                G   V S        AAL+         Q  P+
Sbjct: 420 RPIVLCVDGPEDALTELH-------ALGFPTVESFDGCCATIAALVRLQGVSKRPQDVPA 472

Query: 507 LLENVAVIN----IGLRSFALELQSASKPVVHYQW 537
            +E    +              L  A  PV+  + 
Sbjct: 473 AIEQAGPLAADAFRHELGAKRALAEAGVPVLAERL 507


>UniRef50_Q46UX4 CoA-binding n=2 Tax=Cupriavidus RepID=Q46UX4_RALEJ
          Length = 725

 Score =  196 bits (499), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 88/534 (16%), Positives = 160/534 (29%), Gaps = 54/534 (10%)

Query: 66  VAIRSEAADAGIAQAI-MQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   +        + ++ L E          + S+  +  +  + S        +LA+
Sbjct: 13  IAVIGASTQPDKVGGMPIRLLRELGYAGRIYPVNASAAEVQGLPAYGSLSDIGEPVDLAI 72

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDC 175
           I+V    + ++  Q         +        +    ++ + +L   A++ G+ ++GP+C
Sbjct: 73  IAVPASASQDVMAQLAGNGTRAAVVFTSGFAEAGGAGVQMQERLARSAQQAGITLLGPNC 132

Query: 176 GTSMI-------AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
             +M          +P+A +   P G +G++  SG       +    AG G++H +  G 
Sbjct: 133 LGAMNLRERVFATFSPIALSGTPPVGEVGLVSQSGAFGAYAFALAREAGLGLSHWVTTGN 192

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEA-VRLKIVNAMKATGKPTVALFL 287
                   G+     +E L+ D  + V+    +   +     + + A +A GKP V   +
Sbjct: 193 E------AGLQVADVIEWLAHDPNTRVILAYIEGCRDGARLRRALAAARAAGKPVVVTKV 246

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAA 347
           G T A AR      AS   E A    +       R             L  G   A    
Sbjct: 247 GTTEAGARSAQSHTASLAGEDAVYQAVFEAYGVHRAHTLEEFFRLGYVLSRGRRPATWQR 306

Query: 348 GLLAGH-----LGVEADDTHQHGMMLDADSHQIIDLG----DDFYTVGRPHPMIDPTLRN 398
                      LG+         MM D      + L     D    +    P        
Sbjct: 307 TSGGDADVGTPLGIVTVSGGVGIMMADRAEELGLPLPPMPDDAAAALRTAIPFASTANPI 366

Query: 399 QLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTE 458
            +   + A+P+V +  +  V   GA    A  L                    A     +
Sbjct: 367 DVTGQIVAQPRVFMDAIADVARSGAYGSVAVFLAG--GANAPRFWPELQQAIGALSEAAD 424

Query: 459 RDPQCRS-----QQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLEN--- 510
             P   S      + A LE  G  V      A    A L    +    +   ++      
Sbjct: 425 AAPLMVSGLVDDDKRAWLEARGCLVFREPGHAVEAVATLARAAALEDARGDDAIEGQAQS 484

Query: 511 -----------VAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLER 553
                       A   +        L  A  PV  +  +  A    ++A  L  
Sbjct: 485 DPQDDLLRDIPPAATALSEYEAMRLLAEAGVPVAPHDLARDAEEAVRIAERLGY 538


>UniRef50_A3DLS0 Succinyl-CoA synthetase (ADP-forming) alpha subunit n=7
           Tax=cellular organisms RepID=A3DLS0_STAMF
          Length = 293

 Score =  196 bits (499), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 51/250 (20%), Positives = 111/250 (44%), Gaps = 14/250 (5%)

Query: 66  VAIRSEAADAGIAQA-IMQQLEEALKQLAQGSGSSQALTQVRRWDS---ACQKLPDANLA 121
           V ++      G     +M +    +            +  V  +D+   A + + + + +
Sbjct: 11  VLVQGITGREGSFHTKLMLEYGTKIVAGVTPGKGGMNVYGVPVYDTIYEAVENIGEIDAS 70

Query: 122 LISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMI 180
           +I V  ++A++   +A+D ++  +++ ++ + + +E++    A++K + ++GP+    M+
Sbjct: 71  IIFVPAKFASDAVFEAIDADIKTIVVITEGIPVHEELEFVRYAKKKNITIIGPNTPGIMV 130

Query: 181 AG---TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGG 237
            G     +  A+V   GNIG+I  SGT   E+  +I   G GI+  IGLGG      V G
Sbjct: 131 PGETKIGIMPAHVFKPGNIGLISRSGTLTYEIAREIGKKGYGISTVIGLGGDP----VTG 186

Query: 238 ISALTALEMLSADEKSEVLAFVSKPPAEA-VRLKIVNAMKATGKPTVALFLGYTPAVARD 296
           ++ + A ++ + D  ++ +  + +   +A  R     A     KP VA   G T    + 
Sbjct: 187 LNFIEAYDLFAKDPITKAVVLIGEIGGDAEERFAKYYAELPVKKPVVAYIAGKTAPPGKR 246

Query: 297 ENVWFASSLD 306
                 + + 
Sbjct: 247 MG-HAGAIIS 255


>UniRef50_UPI0000510214 CoA-binding domain protein n=1 Tax=Brevibacterium linens BL2
           RepID=UPI0000510214
          Length = 890

 Score =  196 bits (499), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 61/453 (13%), Positives = 143/453 (31%), Gaps = 40/453 (8%)

Query: 66  VAIRSEAAD-AGIAQAIMQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           V +   +         +++ +  A            +  +  V+ + +       A+LA+
Sbjct: 200 VVVIGASRKRNSTGHLLIRNITAAKFTGDLWVVHPEADQIAGVQAYRTLEDLPGTADLAV 259

Query: 123 ISVAGEYAAELANQALDRNLNVM-MFSDNVTL------EDEIQLKTRAREKGLLVMGPDC 175
           I+V  E A E+  +     +  + + S           E + ++   +R  G+ V+GP+ 
Sbjct: 260 IAVPAESATEVVQECAAHGVKAVLVISSGFAETGDEGAELQRRMVATSRAYGMRVVGPNS 319

Query: 176 GTSMIAGTPLAFANVMPE-----GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
              +     ++    +       G++G+   SG     L S     G GI+  +  G R 
Sbjct: 320 FGLVNEAADVSLNASLAPFLPDSGSLGLFSQSGALGTALLSAAKNRGLGISTFVSAGNR- 378

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
                  +S    L+    D  ++ +    +      +   +    +  KP + +    T
Sbjct: 379 -----ADMSGNDVLQYWEEDPDTKTVGLYLESIGNPRKFSRIARRVSRVKPIIVIKSDLT 433

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLL 350
                  ++   SSL     L  +L +    R          I  L+    + +  +   
Sbjct: 434 GRELPPGHIVRTSSL-APNTLDQVLGQAGVIRA-------DTIHQLFDLAQVFSTQSLPA 485

Query: 351 AGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQV 410
              +GV  +      +++     + + +  +  ++   HP +D       +  + A+  +
Sbjct: 486 GRRVGVIGNSAAMATLLVQRSRSEGLHVEAEPVSL---HPEVDAERFRTELDAMYARDDI 542

Query: 411 RVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIAT 470
             +++      GA     A+ +S                 +A   G        +  +  
Sbjct: 543 DSVIVTFTPSAGAEEAEIAAHLSEAAARSQ-------KTTVACFLGIHGVKDELTTYLTD 595

Query: 471 LEDAGIA-VVSSLPEATLLAAALIHPLSPAAQQ 502
            E A ++  V S         AL      +  +
Sbjct: 596 DEGARVSRTVPSYVGPEDAVWALARATDYSRWR 628


>UniRef50_A0LG54 CoA-binding domain protein n=1 Tax=Syntrophobacter fumaroxidans
           MPOB RepID=A0LG54_SYNFM
          Length = 682

 Score =  196 bits (497), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 70/511 (13%), Positives = 146/511 (28%), Gaps = 68/511 (13%)

Query: 65  CVAIRSEAADAGIAQAIMQQLEEALKQLAQ--GSGSSQALTQVRRWDSACQKLPDANLAL 122
            V +    A   + + +   L E   Q           +    +            +LA 
Sbjct: 10  VVVVGVSNAPGNLGRLMAANLMEFHFQGNIFLVGPKGGSFLGHKIHARITDVDDAIDLAT 69

Query: 123 ISVAGEYAAELANQALDRNL-NVMMFSDNV------TLEDEIQLKTRAREKGLLVMGPDC 175
           I V      E+  Q  ++ +  V++ S          LE E +++       + ++GP+C
Sbjct: 70  ILVPAPAVPEVLRQCGEKGIPRVIVQSAGFRELGEERLELEGKVRDLLEHYRMRMIGPNC 129

Query: 176 GTSMIAGTPLA-----FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
              +   T LA      A  +  G I +I  SG     + + +     G++    +G + 
Sbjct: 130 LGVINRRTGLAVPFFPLAANVGAGPISIISQSGGVGAMMVNLLEAENLGLSRFASVGNKL 189

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
                  +S    LE  + D ++E++    +  A+  +L  +       KP +       
Sbjct: 190 ------DVSENDLLEYFARDPETEMILCYLEGIADGRKLMRITRET--PKPVIVHKSNTG 241

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARRNA-------------IAPVSSGFICGLY 337
              A       AS   +   +     +    R               + P++   +  + 
Sbjct: 242 KCGAAIARSHSASLSSDDRVVDAAFRQSGIIRVREQREAVEVLKAYSLPPLAGNRLAVIS 301

Query: 338 TGG---TLAAEAAGLLAGHLGVEADDTHQHGMMLDADS----HQIIDLGDDFYTVGRPHP 390
             G    LAA+AA      L    +D  Q        +    H  +D+GD          
Sbjct: 302 RSGGHAVLAADAAEEYGFVLPPYPEDFFQLIREQSRANVISFHNPLDVGD---------- 351

Query: 391 MIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYA 450
           + +  L   LI     +  +  ++           +           +    +       
Sbjct: 352 VYNIALYRTLIEKTLEREDIDGMIHV----HNYQGNLNVEESRELISSLGDLIRKYRKPL 407

Query: 451 IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLEN 510
            + V  T  + +     +         + +   EA       +              L  
Sbjct: 408 ASCVFTTRDEFEAIKHAVDF------PIFNDPREAARALKQ-VRDHRSLQT----IPLAG 456

Query: 511 VAVINIGLRSFALELQS-ASKPVVHYQWSPV 540
           V   +I        L+     P+   + +P+
Sbjct: 457 VCPSDIDPSRARKTLEGLNPGPIPAERLAPL 487


>UniRef50_A1SC60 CoA-binding domain protein n=3 Tax=Nocardioides sp. JS614
           RepID=A1SC60_NOCSJ
          Length = 693

 Score =  196 bits (497), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 62/478 (12%), Positives = 127/478 (26%), Gaps = 58/478 (12%)

Query: 66  VAIRSEAADAGIAQAIMQ-QLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
           VA+   +   G   A++   L   +  +   +GS + +  VR + +  +     +LA++ 
Sbjct: 17  VALVGASDRPGSTGALLWENLRGFVGDVYPVNGSGRPVDGVRAYTTLLEIPYPIDLAVLV 76

Query: 125 VAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           V       +   A  R +   +        +       + ++   AR  G+ ++GP+C  
Sbjct: 77  VPATAVPAVVQDAAARGIPACVVITAGFAEAGPGGERLQAEVMKIARVGGVRIVGPNCFG 136

Query: 178 SMIAGTPLAFANVMP----EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
              A   L  +         G++ ++  SG     L S               G +    
Sbjct: 137 VQNAAVGLNASLSPAMTGGSGSLSLVTQSGAYGMALHSLAEDENLCFDKVYATGNK---- 192

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAV 293
                +    L+ L++D  S  + F  +   +      +       +P +    G +   
Sbjct: 193 --ADFTDTELLDYLASDGGSGPICFFLESLPDGRAFVDMARRVTRTRPVIVCRTGRSADG 250

Query: 294 ARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGL---------------YT 338
           +R      AS   +    +   ++                  L                +
Sbjct: 251 SRAARSHTASLAGQQRVWSEAFAQAGITVTRTGLEMLDAARALDRSCPPAGYRIGIVTNS 310

Query: 339 GGT-------LAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPM 391
           GGT       L  E   +    L      T +  +   A     +DL             
Sbjct: 311 GGTGVELTDLLTDEGLEV--PLLSPTLQSTLEKTLPELASPANPVDL--------TTAWQ 360

Query: 392 IDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAI 451
             P L    +  L    +V  ++  ++    +        +         R     +   
Sbjct: 361 RFPELYPFAVDQLARSGEVDAVIAVLLQRSASEPVATGVAM----AVQQLRSAGVDVPVY 416

Query: 452 ATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLE 509
                 +      +     L  AG+AV      A    A                  E
Sbjct: 417 VCWVAAQSARANAAP----LRSAGVAVFEWPERAAKAVAHAARHGQRRKSGAARVSPE 470


>UniRef50_Q89GG9 Bll6376 protein n=1 Tax=Bradyrhizobium japonicum RepID=Q89GG9_BRAJA
          Length = 750

 Score =  195 bits (495), Expect = 5e-48,   Method: Composition-based stats.
 Identities = 97/524 (18%), Positives = 174/524 (33%), Gaps = 65/524 (12%)

Query: 66  VAIRSEAADAGIAQA-IMQQLEEALKQLAQGSGSSQ--ALTQVRRWDSACQKLPDANLAL 122
           VAI   + D+       ++ L EA    A    + +   +  +R +          +LA+
Sbjct: 45  VAIIGASNDSNRIGGRPLRYLREAGFAGAVYPVNPRRNEVQGLRAYADVRDIPGPVDLAI 104

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTL------EDEIQLKTRAREKGLLVMGPDC 175
           + V+ +   E      ++ +   ++FS             + +++  AR  G+ ++GP+C
Sbjct: 105 VIVSADLVVETIEACAEKGIGCAIIFSSGFAEVGPEGARRQQRIEEIARAAGMRLLGPNC 164

Query: 176 GTSMIAGTPLAFA-------NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
             +  + +             VM  G +GV+  SG     L         GI H I  G 
Sbjct: 165 LGAFNSHSGFFGTFTQAFDTGVMFPGELGVVSQSGAAGAHLAYMCRQRCIGIGHWITTGN 224

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRL-KIVNAMKATGKPTVALFL 287
                    I     +E ++     +V+A   +      R  + + A +  GKP +A+ +
Sbjct: 225 E------ADIEVSECVEWMAHAPHVKVIALFVEAIRNGPRFVRALEAAREHGKPVIAIKV 278

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIA---------------PVSSGF 332
           G + A A        + + E      +L +  A R                   P +S  
Sbjct: 279 GRSAAGALAAASHTGALVGEDKIYDAVLRQHGAYRAESIDELLDLTYASLQGRFPSNSRL 338

Query: 333 ICGLYTG--GTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHP 390
                +G  G LAA+AA  +   L V   +    G +             D    G    
Sbjct: 339 GIVTTSGGLGILAADAAVQVG--LAVAPLNEGARGKITAMIPFAGTRNPIDVTAQG---- 392

Query: 391 MIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYA 450
           + +P L ++ IA    +     L+      F  +A    S+ +   +A  +   + P   
Sbjct: 393 VNEPILISRSIACALNEGGYGSLV-----CFLTSAPAVPSIGTPLLQALVSLRQDHPDAV 447

Query: 451 IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLL--AAALIH---PLSPAAQQHTP 505
           IA        P    +Q    E+AG  V   L  A     A  +I     L P+     P
Sbjct: 448 IALEM---VVPPEIRRQY---EEAGFLVFEDLHRAIRTLHALDVIRNGFALQPSCVPDAP 501

Query: 506 SLLENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLAR 549
           +      V +    +  L L     PV+  +         + AR
Sbjct: 502 AATALPDVAD--EYNAKLLLGRHGIPVLAERVVSTPAQAAEAAR 543


>UniRef50_C4ZKF4 CoA-binding domain protein n=1 Tax=Thauera sp. MZ1T
           RepID=C4ZKF4_THASP
          Length = 901

 Score =  194 bits (494), Expect = 6e-48,   Method: Composition-based stats.
 Identities = 73/550 (13%), Positives = 146/550 (26%), Gaps = 89/550 (16%)

Query: 62  NDICVAIRSEAADAGIAQAIM-QQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDA 118
           N   +A+   +A       ++ + L            +    ++  V  + S        
Sbjct: 11  NPRSIAVIGASARERRMGNVLMRNLLSGQFAGPIMPVNPRRTSVAGVLTYPSIAALPQTP 70

Query: 119 NLALISVAGEYAAELANQALDRNLNVMMF----------SDNVTLEDEIQLKTRAREKGL 168
           +LA+I         L  +  +R    +M           +D   +  E  +    R   +
Sbjct: 71  DLAIICTPAPLVPRLVEELGERGARAVMVMANQLDTTLGADGRPI--ERSILEITRRYEM 128

Query: 169 LVMGPDCGTSMIAGTPLAFAN---VMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIG 225
            ++G      ++ G  L           G +G +    T    +         G +H + 
Sbjct: 129 RLLGGGTLGILVPGLGLNATFSQIAARPGKLGFVSQRDTVGTMVLDWALRKKVGFSHFVS 188

Query: 226 LGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVAL 285
           LG      +   I     L+ L+AD  +  +    +   +           A  KP +A+
Sbjct: 189 LG------DSLDIGFGEVLDFLAADSGTRAILLYIESIQDRRAFMSAARAAARNKPVIAI 242

Query: 286 FLGYTPAV----------ARDENVWFASSLDEAARLACLLSRVTARRN---------AIA 326
             G +P                N+     + +AA     + RV                 
Sbjct: 243 KAGRSPDNPLMGVSDPLFLEMPNLVSHDDVHDAALRRAGILRVDQLEEMFGAAETVLRAR 302

Query: 327 PVSSGFICGLYTGGTLA---AEAAGLLAGHLGVEADDTHQHGMMLDAD---SHQIIDLGD 380
           P+    +  L  GG       ++  L    L    + T +      +        +++  
Sbjct: 303 PLRGNRLVVLSNGGGAGLMVEDSLYLAGYSLPALKEQTIERLRRFMSPAWNGRNPLEIRV 362

Query: 381 DFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACA 440
           D               R   I          VLL+       ++ D A  ++        
Sbjct: 363 DSEPACY--------ERLLKILQEERDGD-AVLLIHTPNALSSSIDTAQQVI-------- 405

Query: 441 ARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
           A      +  +    G E       ++     +AGIA   S   A      +      + 
Sbjct: 406 ATARETGINLMTCWVGDE----SVEKERNLFINAGIATFDSPEHAASAFLHMHRHRIASE 461

Query: 501 Q-QHTPSLLE---------NVAVI---------NIGLRSFALELQSASKPVVHYQWSPVA 541
                P+              AVI         ++        L +   PV+    +   
Sbjct: 462 VLMEVPTSEPEAFKPDAARARAVIQGALAQSRASLTESESKDVLAAYGVPVIQTHLAATP 521

Query: 542 GGNKKLARLL 551
               ++A  +
Sbjct: 522 EEAAQIAGRI 531


>UniRef50_B8FIP4 CoA-binding domain protein n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FIP4_DESAA
          Length = 695

 Score =  194 bits (493), Expect = 8e-48,   Method: Composition-based stats.
 Identities = 69/501 (13%), Positives = 146/501 (29%), Gaps = 54/501 (10%)

Query: 62  NDICVAIRS-EAADAGIAQAIMQQLEEALKQLAQGSGSSQA----LTQVRRWDSACQKLP 116
           N   +A+    +  + I +  ++ +     +      + +     +  V+ +    +   
Sbjct: 6   NPQSIAMVGLSSNKSNIPRLSLENMLRWGYRGQIFGVNGRNNDAYVDGVKMFREIDELPI 65

Query: 117 DANLALISVAGEYAAELANQALDRNLNVMM-----FSDNVTLED--EIQLKTRAREKGLL 169
             ++    +  +   ++  +     +  M      FS+     D    Q    AR+ G+ 
Sbjct: 66  IPDIVYSLIPAKLVPDMVERCGKMGVKRMAIPSGGFSEFGGRGDDLAQQTLDAARKYGIR 125

Query: 170 VMGPD--CGTSMIAGTPLAFANVMPE--GNIGVIGASGTGIQELCSQIALAGEGITHAIG 225
            +GP+     ++  G  L FA V+    GNI V+  SG     + +       G+     
Sbjct: 126 FVGPNGLTLANVKNGLCLPFAPVVKPPLGNISVVSQSGGVGLMIMTHFKAENLGMAKFAS 185

Query: 226 LGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVAL 285
           +G +        +  +  LE    D  +E++    +        ++        KP V  
Sbjct: 186 IGNKL------DLDEVDFLEYFGQDPDTEIIFMYLESI--IRGRELAEMASRINKPVVVF 237

Query: 286 FLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNA-------------IAPVSSGF 332
               T +  R      AS   +   L  +       R               + P+    
Sbjct: 238 KSNTTDSGKRAAMSHTASVSSDDHILDAICKDSGIIRIRHFHDFMAVAKAFKLPPMKGPR 297

Query: 333 ICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI 392
           +  +   G L+   A L        AD        L   S+  +    +   +G    + 
Sbjct: 298 VVVMSPAGGLSVMMADLCEESGFEFADPGEAFYESLRNFSNAGVIKFSNPLDLG---DIY 354

Query: 393 DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPA--ASLVSAWQKACAARLDNQPLYA 450
           DP     +I ++    QV   +         + D      L +   K     + +     
Sbjct: 355 DPKFVAHVICEVMHSDQVDGAMYVSFTPDMPSGDSVFKMMLRTDLSKESWGAILSSGKP- 413

Query: 451 IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLEN 510
                G        S     +    + + +S  E     +  +   +   Q       E+
Sbjct: 414 ----LGAALVTPNLSPFKQAIN---VPIFNSPEELVRAMSFQMKYHTRQKQMKDCQGAED 466

Query: 511 VAVINIGLRSFALELQSASKP 531
           +A    GL      L++   P
Sbjct: 467 LA----GLPEAREWLEARKGP 483


>UniRef50_A8ZY45 CoA-binding domain protein n=4 Tax=Desulfobacteraceae
           RepID=A8ZY45_DESOH
          Length = 753

 Score =  193 bits (490), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 62/477 (12%), Positives = 127/477 (26%), Gaps = 52/477 (10%)

Query: 66  VAIRSEAADAGI-AQAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A    +   G     +   +     +      +   + +   + + +      D +LA+
Sbjct: 279 IAFVGASGRLGKWGHLLFTNVLSNGYEGEVYLVNPVRETIAGRKTYPTVSAIPGDVDLAV 338

Query: 123 ISVAGEYAAELANQALDRNLNVMM-FSDNVTL------EDEIQLKTRAREKGLLVMGPDC 175
           +++      +L      + +  M+  S           + E ++  RAR   +L++GP+ 
Sbjct: 339 VTIPAAKVLDLIPDLETKGVKHMLLISSGFGETGEEGKKLEARVVERARAADILMVGPNT 398

Query: 176 GTSMIAGTPLAFANV---MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLS 232
                    L           G I ++  SG    +L       G  I    G G   + 
Sbjct: 399 MGIANPHIKLYCTGTHVWPDPGGIAMVSQSGNMGGQLLQFAEQQGIEIRAFSGSGNEAM- 457

Query: 233 REVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPA 292
                ++    L     DE SE++    +   +  R        +  KP V L  G T  
Sbjct: 458 -----VTIEDYLHAFEVDELSEIVMLYIESVKDGRRFLEYARRLSMKKPIVLLKGGQTKV 512

Query: 293 VARDENVWFASSLDEAARLACLLSRVT--------------ARRNAIAPVSSGFICGLYT 338
             +       +   +A     +  +                A  ++I       I  +  
Sbjct: 513 GEKAAASHTGAMASDARVFDAVCRQSGIVKVDQPMDMLDLSAAFSSIPLPEGNRIGIMTL 572

Query: 339 GGTLAAEAAGLLA------GHLGVEADDTHQHGMMLDADSHQIIDLGDD-----FYTVGR 387
           GG     AA L +        L  +        +         IDL  +        V  
Sbjct: 573 GGGWGVVAADLCSAYNLGVPELTPDILKEMDALLPPYWSRANPIDLVGESSNILPMQVME 632

Query: 388 PHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAW-------QKACA 440
                D       +  +G +   + ++    +    T D    +V           +   
Sbjct: 633 ALLKWDGCDAVINLGIMGKRLITKRIVKSTAVDPTYTPDFLNDVVKVLYKFEEEYVEHVV 692

Query: 441 ARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLS 497
             +D      I     T+        ++A           +   A    A +     
Sbjct: 693 TMMDKYKKPVIGVSIMTDEKEDKTVNKVAG-HKYNALFFPTPERAVKALAKMYDYRR 748


>UniRef50_D2PLU3 CoA-binding domain protein n=2 Tax=Actinomycetales
           RepID=D2PLU3_9ACTO
          Length = 941

 Score =  193 bits (489), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 77/516 (14%), Positives = 156/516 (30%), Gaps = 65/516 (12%)

Query: 34  SVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIM-QQLEEALKQL 92
           SVM         L                   VA+   +   G     + + L +     
Sbjct: 229 SVMQAREQRSEALSIARLLTPA---------SVAVIGASRREGTIGNALLRNLRDGGFPG 279

Query: 93  AQGSGSSQ----ALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMF 147
              + ++      +  V  + +        +LA+++V  E   ++      + +  +++ 
Sbjct: 280 RLSAVNADTSAAEVDGVPAYPTIRDVQDTVDLAVVAVPAEAVVDVVLDCAAKGVRGLVVV 339

Query: 148 SDNVTL------EDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPE-----GNI 196
           S             + +L   AR  G+ V+GP+    +     +     +       G +
Sbjct: 340 SSGFAEIGPEGRRRQRRLVGLARSYGMRVIGPNALGVINTAPGVQLNATLSPLMPSRGRV 399

Query: 197 GVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVL 256
                SG     + + IA  G G++  +  G R        +S    ++   +DE +EV+
Sbjct: 400 AFFCQSGALGVSILADIAGRGLGLSSFVSAGNR------ADVSGNDLMQYWYSDEATEVV 453

Query: 257 AFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLS 316
               +      +   V    A  KP VAL  G          +   S L   A +  L  
Sbjct: 454 LLYLESLGNPRKFSRVARRLAGRKPVVALKSGRATQGVPLGQMVRRSQL-PPATVDSLFR 512

Query: 317 RVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQII 376
           +                  L+    L A         + V  +      + LDA +   +
Sbjct: 513 QSGLIGVDTTGE-------LFDVAQLLAHQPLPKGRRVAVVGNSDALTLLALDAMAGCGL 565

Query: 377 DLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQ 436
           D+  + +T+       D    ++ + ++    +V  +++           P  S  +   
Sbjct: 566 DVAGEPHTLSADASAQD---FDRALTEVFGDDRVDSVVVIF-------TPPVHSNGAEVA 615

Query: 437 KACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAG------IAVVSSLPEATLLAA 490
           +  AA         ++T   +   P    +Q+   ++ G      I   SS   A     
Sbjct: 616 QVLAAAAAGSDKPVVSTFLASRSVP----EQLRVPDEHGGAARGSIPSFSSPQYAV---G 668

Query: 491 ALIHPLSPAAQQHT--PSLLENVAVINIGLRSFALE 524
           AL      A  +     ++ +   V   G   F  E
Sbjct: 669 ALAKATQYAEWRRRADSAIPDLPGVDTAGAEDFVQE 704


>UniRef50_Q0K4A4 Pimeloyl-CoA synthetase n=1 Tax=Ralstonia eutropha H16
           RepID=Q0K4A4_RALEH
          Length = 718

 Score =  192 bits (488), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 76/519 (14%), Positives = 142/519 (27%), Gaps = 45/519 (8%)

Query: 66  VAIRSEAADAGIAQA---IMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   + D            +       +   + S Q +  +R + S        + A+
Sbjct: 22  IAVVGASDDPTRINGRPIAFARRFGYEGAIYPINPSRQTVQGLRAYPSLRDAPDGIDCAI 81

Query: 123 ISVAGEYAAELANQALDRNLNVMM-FSDNVTLEDEI------QLKTRAREKGLLVMGPDC 175
           I++      +  +Q   + +  ++ F+       E       ++   AR  G+ ++GP+ 
Sbjct: 82  IALPAALVIDALHQCAGKGIRAVVLFTSGFAELGEAGQRKQEEITRIARAHGIRLLGPNV 141

Query: 176 GTSMIAGTPL------AFANVMPEG--NIGVIGASGTGIQELCSQIALAGEGITHAIGLG 227
                                +P G   IG++  SG     +       G  +   +  G
Sbjct: 142 IGCFCLSRKTYVTFLSDVDGALPAGKPRIGLVSQSGGYGAHIYKLALQRGLAVDQVVTTG 201

Query: 228 GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKI-VNAMKATGKPTVALF 286
                     I     +E ++     +++    +           + A     KP V + 
Sbjct: 202 NE------ADIELGEVMEWMAESPDVDIIVGYIEGIRSKASFIRGLEAAHRKRKPVVLMK 255

Query: 287 LGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEA 346
           +G T A A       A+     A    LL    A R          +  L  G  L    
Sbjct: 256 VGATQAGAAAAASHTAALAGADAVYDALLREYGAYRARSNEEVLDVVYALSAGKPLR--- 312

Query: 347 AGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRP----HPMIDPTLRNQLIA 402
                  LGV          + D  S   +DL        R      P   P     + A
Sbjct: 313 ----KRKLGVVTISGGAGVQIADFASEAGLDLPMPSEATQRALREIAPFGSPANPVDVTA 368

Query: 403 DLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATV---TGTER 459
            +   P++    LD ++  G        L  A   A A       +  IA          
Sbjct: 369 QISNDPEIFTATLDRLLDAG-YDSLLMWLGPAVTNARAGAPIRATIERIAATRPDVLQTI 427

Query: 460 DPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH-----PLSPAAQQHTPSLLENVAVI 514
           +    ++  +  E AG  +      A    AAL +           +     +       
Sbjct: 428 NLIGGAEVTSVYEAAGCLLFEEPRRAVQALAALRYFERVFSRPLPVRPDVSQMTLLAPDT 487

Query: 515 NIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLER 553
                     L  A   ++  +         + AR + R
Sbjct: 488 TYNEVDAKRVLAGAGVALLDERLVHTPAQAAEAAREIGR 526


>UniRef50_A0NUW5 Putative uncharacterized protein n=2 Tax=Alphaproteobacteria
           RepID=A0NUW5_9RHOB
          Length = 909

 Score =  192 bits (487), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 65/463 (14%), Positives = 120/463 (25%), Gaps = 43/463 (9%)

Query: 66  VAIRSEAADAGIAQAIM---QQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+       G+  + +    Q  EA   +           + R+           +LA+
Sbjct: 15  IAVIGPCRHPGVLTSKLVSCLQDIEAGHPVTLVGIDEVVPFKGRKAARLDDLEKMPDLAI 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMF----SDNVTLEDEIQLKTRAREKGLLVMGPDCGTS 178
                E                ++      +    E   + +  A+   L ++GP     
Sbjct: 75  YLAKAETLPATIRVLGAGGTKAVLIPSPGFETWPEELLQECREAAQATNLRLIGPGTLGL 134

Query: 179 MIAGTPLAF---ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREV 235
            +  T L     A    +G +     SG  +    S       G +  + LG R      
Sbjct: 135 AVPATGLNALLSAERPEKGEVAFFSRSGAVLNATLSWAKAHRTGFSAVVSLGARM----- 189

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVAR 295
             +     ++  + D  +  +    +  A   +        A  KP + +  G +     
Sbjct: 190 -DVDISDLIDYFAQDYHTRAIVLHLEGIAVPRKFISAARAAARSKPVIVIRSGKSRDSGG 248

Query: 296 DENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLY--------------TGGT 341
                             +  R    R          +  L                G +
Sbjct: 249 TGRTHAGRLARTDRVYETVFRRTGLLRVHDLDEMFEALETLSHIRVPQCNKLAVIANGRS 308

Query: 342 LAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPH--PMIDPTLRNQ 399
           LA+ A   L    G  A+        L+  S     L       G       + P    +
Sbjct: 309 LASLAVDRLMDLGGSFAELGPDTRAALEDTSRSYAGLSVTPAAGGSVILKENVTPEQITE 368

Query: 400 LIADLGAKPQVRVLLLDVVIGFGATADPAA--SLVSAWQKACAARLDNQPLYAIATVTGT 457
            I  +   P V   +   V+   +   P +  +   A   A   R   +    +A + G 
Sbjct: 369 AIVTVLKDPNVDGAV---VLQAASAFQPLSAIAKAIADAAALDRRRTGRRKALVAGLIGG 425

Query: 458 ERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
           +          A L +A I   +S  EA      L H      
Sbjct: 426 DG------ATRAALSEARIPNYASPAEAARSLMHLAHDAQARE 462


>UniRef50_A4BCL0 Acyl-CoA synthetase (NDP forming) n=1 Tax=Reinekea blandensis
           MED297 RepID=A4BCL0_9GAMM
          Length = 877

 Score =  192 bits (487), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 65/473 (13%), Positives = 131/473 (27%), Gaps = 54/473 (11%)

Query: 65  CVAIRSEAADAGIAQA-IMQQLEEALKQLAQGS---GSSQALTQVRRWDSACQKLPDANL 120
            +A+   +         ++Q L  +  +    +        +          +     +L
Sbjct: 12  AIAVVGASERESSMGGLVLQNLRSSSFEHPIFAVNLKGYDQVFGYPCVRYLREIETQVDL 71

Query: 121 ALISVAGEYAAELANQALDRNLNVMMF-SDNVTLED------EIQLKTRAREKGLLVMGP 173
           A++ V  E    +  Q    N+   +  +  +  +         ++   ARE G+ +MGP
Sbjct: 72  AILCVPPEVIPRVLRQMGRLNIRAALILTGGLARQLNFNPAMNTKIGELARELGIRLMGP 131

Query: 174 DCGTSMIAGTPLAFANVM---PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
           +C   ++    +  +        G+   IG S      L       G G +H + LG   
Sbjct: 132 NCLGILVPDHHMNASYTHLDALPGSAAYIGHSAALGSALLDWAGARGIGFSHFLTLG--- 188

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
                  I     ++ L+AD + + +    +   +A RL       +  K  +AL     
Sbjct: 189 ---ASADIRISDVVDNLAADRRVKAILIHLEQIRDANRLLTALRAASRSKKVLALRT--H 243

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARR---------NAIAPVSSGFICGLYTGGT 341
              A    V     +D        + +V             +   P+    +  +  G  
Sbjct: 244 STDALPNGVTDIQKIDAEFFARAGVLQVDTVDGLFGGLEILSRSKPLHFRNLAIVSNGMG 303

Query: 342 LAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPH---PMIDPTLRN 398
            A  A   L    G  A       +                 T G P    P        
Sbjct: 304 TAMLARQNLLRQSGELASPIESDYIRAHT--------WYTEETGGNPAILPPQSSGDDYV 355

Query: 399 QLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTE 458
            L+  L  +P +  +L+         +    S  ++  +     +       +    G  
Sbjct: 356 GLLQQLERQPGLGAILV-------IHSPNRRSDSTSVAETLLKHIKRSRRLILTCFLGG- 407

Query: 459 RDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQ-QHTPSLLEN 510
                  +     +  G+    S  EA      L        + + TP+    
Sbjct: 408 ---LTTQEARRIFDGRGLLNFDSPTEAVNAYITLSKHTEAQEKLRETPTTDAL 457


>UniRef50_D1B6J7 CoA-binding domain protein n=1 Tax=Thermanaerovibrio
           acidaminovorans DSM 6589 RepID=D1B6J7_THEAS
          Length = 699

 Score =  191 bits (486), Expect = 5e-47,   Method: Composition-based stats.
 Identities = 71/524 (13%), Positives = 162/524 (30%), Gaps = 54/524 (10%)

Query: 66  VAIRSEAAD-AGIAQAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +++   I+   ++ L +          +    ++  +R +        D ++AL
Sbjct: 18  VAVVGASSNLESISGRPLKLLLKYGYGGGVYPVNPKYDSIGGLRCYPDVGSIDGDVDVAL 77

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLE----DEIQLKTRAREKGLLVMGPDCGT 177
           ++V       +      R +   ++FS           + +L   A   G+ ++GP+C  
Sbjct: 78  VAVRAPLVPSVIEGCGRRGIRFAVVFSSGFAEAGREDLQRELLEAADRWGVRILGPNCQG 137

Query: 178 SMI--AGTPLAFANVM--------PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLG 227
            +    G PL+F+  +          G I  +  SG       +     G    H +  G
Sbjct: 138 LVNLAGGIPLSFSASLDTDRLVGATPGGIAYVSQSGAFGFASFACAVDRGVRFRHVVTTG 197

Query: 228 GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVN-AMKATGKPTVALF 286
            +        +  +     L  D +  +L    +   +  RL  +    +        + 
Sbjct: 198 NQ------ADLDTVEVAGCLLEDPEVRMLLLYLEGVRDGDRLVELLIRARERDVTVGLIK 251

Query: 287 LGYTPAVARDENVWFASSLDEAARLACLLSRVTARR--------NAIAPVSSGFICGLYT 338
            G +   +R      AS   +      ++ +  A          +           G   
Sbjct: 252 AGRSETGSRAAQSHTASVAGDQRVWGAVMEQYGAVMLGDMEDMISLGLACGLPRPRGRRV 311

Query: 339 GGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI-----D 393
           G    +  AG++   L   +D   Q  ++ +    +I  +   F +   P  +      D
Sbjct: 312 GIITTSGGAGIMMADL--CSDQGLQVPLLDEGTQERIRRVIPPFGSPANPVDVTAQVIND 369

Query: 394 PTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIAT 453
           P    + ++ L A P V ++ + + +              +  +  A    +     + +
Sbjct: 370 PQGMTECLSALEADPNVDMMSVVISM-------ITGQAGESTARQVADFAASSRKPLVCS 422

Query: 454 VTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLL--ENV 511
                 D +      + L + G+ V+ SL +A     A+  P         P L   + +
Sbjct: 423 WL---IDREHGGDLTSYLSERGVPVIGSLRQAAWTLGAISRPRGSFLSGDLPGLPCDDPL 479

Query: 512 AVIN--IGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLER 553
             +   +        L++   PV   +        +  A  +  
Sbjct: 480 RGLEGLLTEHQAKQVLKAWGVPVTMEEMVRDPDEARVAAERIGY 523


>UniRef50_C0GIF8 CoA-binding domain protein n=1 Tax=Dethiobacter alkaliphilus AHT 1
           RepID=C0GIF8_9FIRM
          Length = 716

 Score =  190 bits (483), Expect = 9e-47,   Method: Composition-based stats.
 Identities = 80/547 (14%), Positives = 157/547 (28%), Gaps = 81/547 (14%)

Query: 53  HDDFNNATPNDICVAIRSEAADA-GIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSA 111
           +  +    P  I +A         G   A+         +      + + +   + + + 
Sbjct: 4   NPLYKLMNPGSIAIAGAGNNPRKMGTLHALNILKGGYGGKFFPLHPTEETVLGHKAYRTV 63

Query: 112 CQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNV------TLEDEIQLKTRAR 164
            Q      L ++ V  + A  L ++         ++ +           + E +L+  AR
Sbjct: 64  DQLPQVPELVMLIVPTDAALHLLDEFGRLGTRRAIVVTSGFRETGAAGQKKEEELQEIAR 123

Query: 165 EKGLLVMGPDCGTSMIAGTPLAFANVM---PEGNIGVIGASGTGIQELCSQIALAGEGIT 221
              +  +GP+C   M +   L    +      G +G+   SGT + +  S +   G   +
Sbjct: 124 RHNIRFLGPNCIGMMNSQISLNTTVMPLSGQPGRLGMASQSGTYVTQTFSYLKERGIHFS 183

Query: 222 HAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKP 281
            AI +G          I    ALE L  DE+++ +A   +   +  R   V       KP
Sbjct: 184 KAISVGNET------DIDITDALEYLGQDEETKAIALYIEGIKDGARFIDVAQKITPHKP 237

Query: 282 TVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARR--------------NAIAP 327
            +A ++G + A AR       S          +  +    R               +  P
Sbjct: 238 VIAQYVGGSAAGARAGMSHTGSMAGPDFLYEGIFKQAGIIRVDTVEDLYLNGWMLASQPP 297

Query: 328 VSSGFICGLYTGGTLAA------EAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDD 381
           +    +  +   G          +   L       +  +  +  +   A S   +DL  D
Sbjct: 298 MRGSRVGVVTNSGGPGTAISDTCDKNNLEVPRFSPQLQEQIRQLIQAQASSTNPVDLTFD 357

Query: 382 FYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAA 441
                R   ++ P L       +    +V  L+L   +  G       ++    Q+    
Sbjct: 358 L--NARNLSVVIPEL-------IMQSGEVDGLVLHGAMSHG----FLRAIHPYLQEMLGG 404

Query: 442 RLDNQPLYAIATVTGTERDPQCRSQQ---------------IATLEDAGIAVVSSLPEAT 486
                 L     V  T+        Q                A      I V  +  +A 
Sbjct: 405 ISLEGFLAQF-PVDFTDMVSLPVKYQLPMAVSSFFGNEDNYTAAFRSHSIPVFDAPEKAA 463

Query: 487 LLAAALIHPLSPAAQQHT-PSLLENVAVIN--------------IGLRSFALELQSASKP 531
              +AL        ++    + L  +AV                +        L +   P
Sbjct: 464 KAMSALHRHKEIRERKEIERTPLPALAVEAEKIIAEAVAAGRQVLDEYQAKQVLAAYGIP 523

Query: 532 VVHYQWS 538
           V   + +
Sbjct: 524 VTRERLA 530


>UniRef50_C5T5T1 CoA-binding domain protein n=1 Tax=Acidovorax delafieldii 2AN
           RepID=C5T5T1_ACIDE
          Length = 713

 Score =  190 bits (483), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 70/468 (14%), Positives = 144/468 (30%), Gaps = 55/468 (11%)

Query: 66  VAIRSEAADAGIAQAIMQQLEE---ALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   + ++G    +   L         +   +   + +   R +          +LA+
Sbjct: 14  IAMIGASNNSGRIGGMPLDLLRHFRYAGDVYPINPKYEEVFGYRCYPDVEALPQAPDLAV 73

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDC 175
           +++A E    +  +   R +   +        + +  +E + +L+  A+  G+++ GP+C
Sbjct: 74  LAIAAEDVTSMLERCHARGIRAAIVYAAGFAEAGSAGVELQARLEQFAQRTGMVIAGPNC 133

Query: 176 GTS--MIAGTPLAFANVMPE-------GNIGVIGASGTGIQELCSQIALAGEGITHAIGL 226
                +      AFA V          G   +I  SG     + + I   G  ++H I  
Sbjct: 134 MGFANINTHAYTAFAAVFKNVPVQTQCGRASIITQSGNVCSAVFALIRKLGIPVSHFINT 193

Query: 227 GGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK-IVNAMKATGKPTVAL 285
           G   +            LE ++ D+ +E +    +      R      A+ A  KP +  
Sbjct: 194 GNEAVVE------FSEYLEYMAQDDATECVIGYVEQLRNGPRFIHAALALAAQKKPLIIY 247

Query: 286 FLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSG--FICG-LYTGGTL 342
             G T   +       ++   + A      +++   R       +   ++ G  +  G  
Sbjct: 248 KAGETDKGSEAVRSHTSALAGDLALYKAGFAQLNVIRGNDFAQMADLAYLSGYRHRAGGS 307

Query: 343 AAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYT-VGRPHPMID-------- 393
                 +      + AD     G+ +   S  +     D     G     +D        
Sbjct: 308 RVAIVTMSGALGAILADKMIGAGLQVPTLSDDLQRTLRDGIPDYGMVSNPVDVTGNVVNS 367

Query: 394 PTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIAT 453
           P     +   LG   QV  +++               L+    +             +A 
Sbjct: 368 PEFVRTIFQALGETDQVDTVIVYAP----------GYLLDRMAEPLVEMAGRYSKLFVAI 417

Query: 454 VTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQ 501
            TG        +Q    L  AGI V   +  AT   A     ++   Q
Sbjct: 418 DTGA-------AQCRERLSGAGIPVFDDIGRATQALAPFCQWMARHEQ 458


>UniRef50_Q46SD8 CoA-binding n=11 Tax=cellular organisms RepID=Q46SD8_RALEJ
          Length = 712

 Score =  190 bits (482), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 77/510 (15%), Positives = 142/510 (27%), Gaps = 62/510 (12%)

Query: 66  VAIRSEAADAGI-AQAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +AD    A   +  L            +    A+  VR +          ++ +
Sbjct: 28  VAVIGASADPAKTAGRPVSYLLRHGYSGAIYPVNPKVDAIAGVRCYPDISSLPEVPDVGI 87

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-----SDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           + +  E A     +   R     +      ++        Q +       + ++GP+   
Sbjct: 88  VLLGAERAHHAVRELAARGTGAAIVLASGYTETGAEGARRQAELVEAAGKMRLLGPNTIG 147

Query: 178 SMIAGTPLAFANV-------MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
            +     +  +          P G IGV+  SG  +  + S+ A  G G++  +      
Sbjct: 148 LVNVTESIPLSASGALEMDKFPAGGIGVVSQSGGILGAVLSRAAARGVGLSKLVSTSNE- 206

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKAT-GKPTVALFLGY 289
                  +     ++ L+ D  + V+A   +      + +      A  GKP VA  +G 
Sbjct: 207 -----ADLDLSDFIDYLADDPATRVIALYVESVRHPDKFRAAALKAARAGKPVVAFKIGR 261

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTG---------- 339
           + A AR       +          L ++V   R             L  G          
Sbjct: 262 SEAGARAAVSHTGAMAGADRMYDALFAQVGIIRAHAFSDLIDIPAALAAGRRLNGKRIAV 321

Query: 340 -------GTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI 392
                  GTL +++ G+           T Q    L    H  +D      T+      +
Sbjct: 322 LTSTGGAGTLVSDSLGVSGFETPPPDTATAQQLRALQRGDHAALDRNPIDVTLA----GL 377

Query: 393 DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIA 452
            P L    I  L A P    + + V     A     A        A    L       +A
Sbjct: 378 QPDLLRSAIRILLASPAYDAVAVIVGSSGLAMPHLMA-------DAITDCLPESDKPVLA 430

Query: 453 TVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLEN-- 510
            V+          +  A L   G+   S+     +   A++           P+      
Sbjct: 431 YVSPHAP------EAAAVLNQRGVPAFSAPESCAVAFGAMLSVQRLVRNDDAPTPEAEFI 484

Query: 511 ----VAVINIGLRSFALELQSASKPVVHYQ 536
               +    +   +          P V  Q
Sbjct: 485 DTTDLLPGPMDEAAAKQLFARFGVPGVREQ 514


>UniRef50_Q13HH2 Putative CoA ligase n=1 Tax=Burkholderia xenovorans LB400
           RepID=Q13HH2_BURXL
          Length = 708

 Score =  188 bits (477), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 62/486 (12%), Positives = 132/486 (27%), Gaps = 58/486 (11%)

Query: 67  AIRSEAADAGIAQAIMQQLEEALKQLAQ--GSGSSQALTQVRRWDSACQKLPDANLALIS 124
           AI   +     ++  +Q+L++          +  +  +   R   +        ++AL+ 
Sbjct: 16  AIIGASERNFYSRNALQRLQDCGYAGKVHLVNPGTSEVFGKRCHANVKDIGESIDMALVV 75

Query: 125 VAGEYAAELANQALDRNLNVMMFS--------DNVTLEDEIQLKTRAREKGLLVMGPDCG 176
           V            ++      +          D V L  + +L     E  + + GP C 
Sbjct: 76  VPRTAVIGALRDCVEAGAKAAVVVSTGFGESHDAVGLALQRELSEFLDEHPIALCGPSCL 135

Query: 177 TSMIAGTPLAFANVMP-----EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
             +            P      G+IG++  SG  +       +    G ++ +  G    
Sbjct: 136 GVVNMIDGFQAFGGHPGTEILPGSIGLVSQSGANVHSYIGAASARNLGFSYVVSSGNE-- 193

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRL-KIVNAMKATGKPTVALFLGYT 290
                G+ A   ++    D  ++V+    +    +  L ++        KP + + +G +
Sbjct: 194 ----AGMDATDYIDCFLRDPDTKVVCAYIESFKSSDALIRVAEQALKVSKPLIVIKIGRS 249

Query: 291 PAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTG------GTLAA 344
           P+  R       +          L  +    R      S    C   +           A
Sbjct: 250 PSAVRAALAHTGAMTGPDHYFDTLFRQYGIIRANTIEESLDRACIFASSQEAYWPSGRRA 309

Query: 345 EAAGLLAGHLGVEADDTHQHGMM-LDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQL--- 400
               +  G     +D +   G    + D+  +  L +       P   ID + + +    
Sbjct: 310 GVVSVSGGFAATLSDLSRDGGFDVPELDASSVRKLLEVLPANVNPQNPIDISTQVRRDRS 369

Query: 401 ------IADLGAKPQVRVLL-----------------LDVVIGFGATADPAASLVSAWQK 437
                 +  +   P V  +L                 + +  G        +  +     
Sbjct: 370 DAWERTVNCMADDPNVDFVLNGEAVPLDDDRLQELTSIRLRTGKPVLLASTSPHIQILND 429

Query: 438 ACAARLDNQPLYAIATVTGTERDPQCRSQ--QIATLEDAGIAVVSSLPEAT-LLAAALIH 494
           A  A      L  +  V G  R  Q          L    +        A    A  ++H
Sbjct: 430 AQRAWCREHRLPVVVGVEGCHRAIQSTLDFTAKVVLARDSVKRSEMPVAALPRPAGHVLH 489

Query: 495 PLSPAA 500
            +    
Sbjct: 490 EVKARE 495


>UniRef50_UPI0001C30E25 CoA-binding domain protein n=1 Tax=Conexibacter woesei DSM 14684
           RepID=UPI0001C30E25
          Length = 904

 Score =  188 bits (477), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 75/430 (17%), Positives = 129/430 (30%), Gaps = 57/430 (13%)

Query: 66  VAIRSEAADAGIAQAI-MQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+     DA          L  +    A        +A+   R + S  +   + +LA+
Sbjct: 210 IAVLGATHDAATIGGAVFANLVASGYTGALHAVERRGRAIGSHRCYRSLDEVPDEIDLAV 269

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDC 175
           ++V        A    +R +  +         S       + +L    R  G+ ++GP+C
Sbjct: 270 LAVPAGEVLGAARACGERGVRALAVLAAGFAESGPDGAARQRELLRACRGAGMRLVGPNC 329

Query: 176 GTSMIAGTPL----AFANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRD 230
              +     +     FA   P  G IG++  SG     L  Q    G G++  + +G + 
Sbjct: 330 LGVLNTDPRVRLDATFAPSHPPAGGIGLLSQSGGVGIALLEQARALGIGVSTFVSVGNK- 388

Query: 231 LSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYT 290
                  +S    LE    DE++  +    +      +   +       KP VA+  G T
Sbjct: 389 -----ADLSGNDFLEWSEQDERTRAILLYLESFGNPRKFARIARRVGQRKPIVAVKAGRT 443

Query: 291 PAVARDENVWFASSL-DEAARLACLLSRVTARRN---------------AIAPVSSGFIC 334
            A AR  +    + L      +A L  +    R                   P       
Sbjct: 444 AAGARAASSHTGALLASSELAVAALFRQAGVLRVDTLGELFDLAALLERQPLPAGRRVAI 503

Query: 335 GLYTG--GTLAAEAAGLLAGHLGVEADDTHQHGMMLDADS---HQIIDLGDDFYTVGRPH 389
               G  G LAA+A       L    +   +    +   S      +DL  D        
Sbjct: 504 VTNAGGPGILAADACQAAGLELPRLPEPLRRRLAAIVPASAGLANPVDLLVDAT------ 557

Query: 390 PMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLY 449
               P      +  +G    V  ++   V    A    A  +  A + A  A      L 
Sbjct: 558 ----PQAFAGAVEAIGRAGAVDAVIAVFVPRPFAR---AEEVAGALRDAAGALA--GRLP 608

Query: 450 AIATVTGTER 459
            +      ER
Sbjct: 609 LLPVFMTGER 618


>UniRef50_Q2LVD4 Acetyl-CoA synthetase beta subunit n=1 Tax=Syntrophus
           aciditrophicus SB RepID=Q2LVD4_SYNAS
          Length = 773

 Score =  188 bits (476), Expect = 7e-46,   Method: Composition-based stats.
 Identities = 56/383 (14%), Positives = 108/383 (28%), Gaps = 34/383 (8%)

Query: 66  VAIRSEAADAGI-AQAIMQQLEEALKQLAQGSGS--SQALTQVRRWDSACQKLPDANLAL 122
           +AI   + D      ++++ + +          +        ++ ++S        +LAL
Sbjct: 297 IAIVGASDDVTKWGGSVLRNILDGGYTGKVYPVNARGGVFFGLQSYESIEALPEAPDLAL 356

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDC 175
           ++V G   A +  +   + +   +        +     E E  +   A E G+ VMGP+C
Sbjct: 357 LTVGGRQVASMLKECGRKQIPAAIAIAAGFSETGAAGAEAEQDIARIATEGGVTVMGPNC 416

Query: 176 GTSMIAGTPLAFANVMP----EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
              +     L     +      G +  +  SG    ++ +     G GI     +G    
Sbjct: 417 MGMISNEVQLHAVGFVALHPARGTLSFVSQSGNLGSQVVNGCRRRGIGIDKFASVGNEAQ 476

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
              V        L+ L  D  +  +    +   +           A  KP V L  G T 
Sbjct: 477 IGAV------NVLDYLRDDPNTSCVLMYIEGIDDGRLFLDAARRTAAVKPVVVLRAGLTE 530

Query: 292 AVARDENVWFASSLDEAARLACLLSRVTARRNAIAP--------------VSSGFICGLY 337
           + ++       +    AA       +                             I  + 
Sbjct: 531 SGSKAAASHTGAMAGSAAVWEAAARQAGVVTCLTTDALLDLGSCLACNPLPRGRRIAVVT 590

Query: 338 TGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLR 397
            GG     AA  +A H    A    +    LD          +    V        P + 
Sbjct: 591 QGGGAGVMAADAVARHGLHLAKLPAELYAALDKILPPFWSRRNPLDLVASAGGETGPRVL 650

Query: 398 NQLIADLGAKPQVRVLLLDVVIG 420
             +         + + LL V + 
Sbjct: 651 RTVAECDAVDAVIALSLLGVPMS 673


>UniRef50_Q2LPY1 Acetyl-CoA synthetase beta subunit n=1 Tax=Syntrophus
           aciditrophicus SB RepID=Q2LPY1_SYNAS
          Length = 700

 Score =  188 bits (476), Expect = 7e-46,   Method: Composition-based stats.
 Identities = 59/476 (12%), Positives = 126/476 (26%), Gaps = 65/476 (13%)

Query: 65  CVAIRSEAADAGIAQAIMQQLEEAL--KQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
            V + +      +   I+    +     +L         +  V  + +        +LAL
Sbjct: 10  MVVVGASPTKQNLGHLILINNVQRGCTVRLYGVGSEEGEIAGVHVYRNVADLPEVPDLAL 69

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-SDNVTL-------EDEIQLKTRAREKGLLVMGPD 174
             +      +   +     +  ++  S   +          E +L   A    +  +GP+
Sbjct: 70  FIIPAAAIPDQLEECGKLGIRRVVIESGGFSEFSREKSNALEEKLLDIAACHDIRFIGPN 129

Query: 175 CGTSMIAGTP-----LAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
           C  ++          L + N +P G +G+I  SG         +          + +G +
Sbjct: 130 CIGAVNYDLNLLMPFLLYKNTLPGGRVGIISQSGGIGHYYLEHLPENSVRPGKMVSIGNK 189

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
                   I     LE    DE ++ +    +           +   +  KP +      
Sbjct: 190 LQ------IDETDFLEYFLEDEHTDQVIIYLEGFKRGRDF--FHTALSASKPVILHKANR 241

Query: 290 TPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGL------------- 336
            P  A       A+       +  L  +    R      +   +  L             
Sbjct: 242 NPQSALIARSHSAALSASDDVVDGLCRQAAIIRVEDDEEAIRSVKILQQPLMRGRRIAVL 301

Query: 337 -YTGG--TLAAEAAGLLAGHLGVEADDTHQHGMML----DADSHQIIDLGDDFYTVGRPH 389
             +GG   ++A+A       L    D        L           +DLG+         
Sbjct: 302 SRSGGHAVISADACSQYGFELVPFPDSFFDKLDTLYRQRVIARQNPLDLGE--------- 352

Query: 390 PMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLY 449
            + D  +  +++ +      V  +L + +      A+ + + +               + 
Sbjct: 353 -IFDYRIYGRILEETLKLDCVDGVLFNHIYQSHYEAEMSRTFLGELDGLIRKYNKPVAVA 411

Query: 450 AIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTP 505
           AI  V  T    +               V +S   A     A         ++ T 
Sbjct: 412 AITDVAETTELVKNY------------PVYASPLAAIKALNASAAYARQRERRDTR 455


>UniRef50_A4FCG4 Acyl-CoA synthetase (NDP forming type) n=2 Tax=Actinomycetales
           RepID=A4FCG4_SACEN
          Length = 892

 Score =  186 bits (473), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 76/465 (16%), Positives = 148/465 (31%), Gaps = 39/465 (8%)

Query: 65  CVAIRSEAADAGIAQ-AIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLA 121
           CVA+     D      A+ +++  A  +      +  ++ +  +  +    +     +L 
Sbjct: 197 CVAVVGAGRDRSSVGNAVFRKVLAAGFRGNCYPVNRHARTVESLPAFADVEELPEVPDLV 256

Query: 122 LISVAGEYAAELANQALDRNLNV-MMFSDNVTLEDEIQ--LKTRAREKGLLVMGPDCGTS 178
           ++ V  E   ++A     + +   ++ S  VT +  +   L    R  G+ ++GP+C   
Sbjct: 257 VVCVPAEAVPQVAESCGRKGVRALVVVSAGVTSDPVLAHGLVDAVRRWGMRLVGPNCLGV 316

Query: 179 MIAGTPLAF-----ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
           +     +       +   P G++GVI  SG     L   +A  G G++  + +G +    
Sbjct: 317 INTDPDVRLDATFTSGCAPAGDVGVITQSGGVGIALLDGLAACGLGVSSVVSVGDKY--- 373

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAV 293
               +S    L     DE++ +     +      +   ++   A GKP + L  G +P  
Sbjct: 374 ---DVSGNDMLLWWQRDERTRLAVVYLESFGNPRKFSWLSRRMARGKPVIVLKSGASPVA 430

Query: 294 ARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLY-----TGGTLAAEAAG 348
                   A+S         LL +  A            +C L       GG +A     
Sbjct: 431 QAAAASHTAASATPGTTRDALLRQSGAIGVQGLHDLFATVCLLRWQPLPKGGRVAVLGNA 490

Query: 349 LLAGHLGVEADDTHQHGMMLDADS--HQIIDLGDDFYTVGRPHPMIDP---TLRNQLIAD 403
                L  EA       +   + +   ++  +     +   P             Q +  
Sbjct: 491 GGLAALAAEACADRGLRLPELSSALRAELASVLPGQASTRNPVDTTAQCGSAGFAQSLRA 550

Query: 404 LGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQC 463
           L    +V    + VV+   A ADP   +     +A   R        +    G  R    
Sbjct: 551 LLRSGEVNS--VVVVVTATAVADPLPVVADTAAEAQ--RGQEFGKPVLVVRAGHSRAVDS 606

Query: 464 RSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLL 508
            + Q        + V S    A    A +      A  +  P  +
Sbjct: 607 VTSQACR-----VPVFSDPAVAARALAGVS---DYARWRLVPPGV 643


>UniRef50_Q0FX08 CoA-binding protein n=1 Tax=Roseovarius sp. HTCC2601
           RepID=Q0FX08_9RHOB
          Length = 701

 Score =  186 bits (472), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 71/474 (14%), Positives = 146/474 (30%), Gaps = 67/474 (14%)

Query: 67  AIRSEAAD-AGIAQAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLALI 123
           A+   +AD        ++QL +   +      +  +  +  +  +          +   I
Sbjct: 18  ALVGASADLRKFGGRCLKQLVDFGYEGRIYPVNPKADTILGMPCYPDIASLPEAPDHVGI 77

Query: 124 SVAGEYAAELANQALDRNLNVM-MFSDNVTLED-------EIQLKTRAREKGLLVMGPDC 175
            V G+    +  Q  DR +  + +FS   +          + ++   ARE G+ +MGP+C
Sbjct: 78  VVPGKAIPGVLKQCGDRGVRHVTIFSSGFSEGGSADGAAFQAEIVALAREHGIRLMGPNC 137

Query: 176 GTSMIAGTPLAFANVM-------PEGNIGVIGASGTGIQE-LCSQIALAGEGITHAIGLG 227
              +      A  +         P+G++ V+G SG   Q  +  +   AG GI++ +  G
Sbjct: 138 NGLINYVDGFALTSTATINGPRAPKGDVAVLGHSGGLAQVNVMYRAQQAGLGISYQVSCG 197

Query: 228 GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIV-NAMKATGKPTVALF 286
                     +  L     +  D ++ V+  +++   +  +L+ + +  +A  KP V + 
Sbjct: 198 ND------ADLDILDYAAFMVDDPETRVILMLAETIRDGGKLRALSDRARAADKPIVMMK 251

Query: 287 LGYTPAVARDENVWFASSLDEAARLACLLSRVTARRN---------------AIAPVSSG 331
           LG +    +       +     +    +L ++   R                       G
Sbjct: 252 LGRSEEGMQAAVSHTGALASSDSVADDVLRQLGILRVDDCHEMIDVAMMLRTGRRLGGRG 311

Query: 332 FICGLYTGGTLAAEAA-----GLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVG 386
                 +GG L   A      GL     G          +     +    D+        
Sbjct: 312 LAAVSISGGNLVHLADQGPMHGLAFPDFGSATKTRMAELIPNYGQASNPADVTSAA---- 367

Query: 387 RPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQ 446
               +  P +   ++  +   P V V+L  + +                 +  A  L   
Sbjct: 368 ----IGSPEIFAGVLETIAQDPAVDVILPVLTLHSA-----------ELIRGTAQALLAS 412

Query: 447 PLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
           P       +G   D    +     L   G+ V   +  A  +  A       A 
Sbjct: 413 PKPCAVIWSGNCTDDDTLTHAE--LVRMGLPVFRDIAPAMQVIDAAARYAELAQ 464


>UniRef50_Q330N6 Acetyl-CoA synthetase (ADP-forming) alpha subunit n=1
           Tax=Haloarcula sp. D1 RepID=Q330N6_9EURY
          Length = 453

 Score =  186 bits (472), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 67/454 (14%), Positives = 133/454 (29%), Gaps = 61/454 (13%)

Query: 62  NDICVAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQA-LTQVRRWDSACQKLPDAN 119
           +   VA+   +   G      M    E    +   + SS   L  V   DS      D +
Sbjct: 3   DPSAVAVVGASETEGKIGYEAMANAMEFDGPVYPVNPSSDGDLFGVPFVDSVTDIDDDVD 62

Query: 120 LALISVAGEYAAELANQALDRNLNVMMFSDNV-------TLEDEIQLKTRAREKGLLVMG 172
           LAL  V G    ++  +  +  +  ++                +  +   A E G+ ++G
Sbjct: 63  LALCCVPGPATPDVVAECGEAGVGAVVIYAGGFAEAGDEGERLQRAVVETAEEYGISLLG 122

Query: 173 PDCGTSMIAGTPL-----AFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLG 227
           P+    ++  T L     + A  +PEGN  VI  SG     L  Q    G G++  +GLG
Sbjct: 123 PNTSGFVVPATDLLCSFASGAEKLPEGNTAVIAQSGGIAHVLAFQSRRQGRGVSAMVGLG 182

Query: 228 GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFL 287
            R        +     +E    D++++ +    +   +   L  + A + +  P +A  +
Sbjct: 183 NR------ANVGFTETIEYFDGDDRTDAIVLHVEGTDDGRGL--LEACRDSDTPVIAYKV 234

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGL----------- 336
           G +            +   +        ++                  L           
Sbjct: 235 GQSDVG-EFAESHTGALTGDHELYTAGFAQYGVPTVTATDELLDAAAALGDSPVPDGPNV 293

Query: 337 ------YTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHP 390
                    G +  +      G L     +T +    +       +    +    GRP P
Sbjct: 294 GVVTAQAGPGIIITDRLQRAGGRLPALTAETQERIDGIL----PGVTYTGNPVDTGRPMP 349

Query: 391 MIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYA 450
                    ++  +     V ++L+   +   +   P  +L            +      
Sbjct: 350 -----EFGDVVTAVAEDAAVDIVLV-YELFEQSVGFPVDAL--------DGLAERVEKPV 395

Query: 451 IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPE 484
           +    G E D    +   A L    + V  +   
Sbjct: 396 LFATDGIEED---MADDKAALAAVDVPVFETPER 426


>UniRef50_A0QZM0 CoA-binding protein n=3 Tax=Corynebacterineae RepID=A0QZM0_MYCS2
          Length = 687

 Score =  186 bits (471), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 69/471 (14%), Positives = 140/471 (29%), Gaps = 37/471 (7%)

Query: 66  VAIRSEAADAGIAQ---AIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   + D        ++        + +   +    ++       S  +     +L  
Sbjct: 15  VAVLGASNDETKYGNWMSVQALRMTGTRPVYLINRRGDSVLGQPPLRSLAEVDGAVDLVA 74

Query: 123 ISVAGEYAAELANQALDRNLNVMM-----FSDNVTLED--EIQLKTRAREKGLLVMGPDC 175
           I+V           AL      ++     F++        + ++  R R  G +++GP+C
Sbjct: 75  ITVPAHSFEAAVEDALAAGARAIVGVTAGFAELGPEGRALQDRVVDRVRSAGAVLLGPNC 134

Query: 176 GTSMIAGTPLAFANVMPEG-NIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSRE 234
              + + T L FA+    G  + ++  SG    E+   +   G G +    LG +     
Sbjct: 135 LGVIDSTTNLTFASNPLPGGRVALLSQSGNMALEVSGFLQSRGHGFSRFASLGNQ----- 189

Query: 235 VGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKA-TGKPTVALFLGYTPAV 293
              +     ++   A   ++++A   +   +        A  A   KP + L +G + A 
Sbjct: 190 -ADLGVADLIDSCVAHNGTDLIALYCEDFGDGRSFVSAAAAAAAANKPVLLLTVGGSEAS 248

Query: 294 ARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGH 353
            R       +   ++A +          R       +     L T G        ++A  
Sbjct: 249 VRGAQSHTGALTSDSAVIDAACHAAGIYRVTSPRQLADVAATLLTYGRRRVHRVAVIADG 308

Query: 354 LG-------VEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI-----DPTLRNQLI 401
            G       V   +         A S  +  L      V  P  +      D      ++
Sbjct: 309 GGHAGVGSDVVEANGLSVPRFPTALSTALRPLLPPSAGVTNPVDIAGGGEQDIGCFASVL 368

Query: 402 ADLGAKPQVR-VLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERD 460
             + +  ++  VLL     G+    +  A          A          +         
Sbjct: 369 DAVMSSAEIDSVLLTGYFGGYAEYGEGLARDELDVAARIATIAQTHQKPLVVHTM----- 423

Query: 461 PQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENV 511
               S+    L DAG+ V +++ +A    A +     P      P   E  
Sbjct: 424 -HSASKAARVLIDAGVPVFAAVDDAAGALAVIDRGTDPRPLPSLPGTAEKP 473


>UniRef50_C7LZH4 GCN5-related N-acetyltransferase n=1 Tax=Acidimicrobium
           ferrooxidans DSM 10331 RepID=C7LZH4_ACIFD
          Length = 867

 Score =  185 bits (470), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 76/477 (15%), Positives = 138/477 (28%), Gaps = 63/477 (13%)

Query: 62  NDICVAIRSEAADAGIAQAIM-QQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDA 118
           N   VA+   +   G    ++   L  A  + +    + ++ A+  +    S        
Sbjct: 204 NPTRVALVGASRTPGSVGDVLLANLLSARFEGSLWVVNPNAAAVRGIPTVPSLRAIGQPI 263

Query: 119 NLALISVAGEYAAELANQALDRNLNV-MMFSDNVT------LEDEIQLKTRAREKGLLVM 171
           +LA+++V  E    +   A    +   ++ +   +       E+E +L   AR  G+ V+
Sbjct: 264 DLAIVAVRAEELPLVLEDAHAAEVRALVVVTAGFSDIGPEGAEEERRLVASARRLGMRVV 323

Query: 172 GPDCGTSMIAGTPLA---FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
           GP+          LA       +  G   V   SG     + +++A A  GI   +  G 
Sbjct: 324 GPNSMGVASPAIGLAGTLAPFALEAGGTSVHAQSGPLSLAIVAKLAQASIGIASFVSSGN 383

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFL- 287
           +        IS    L     DE++  +    +          V    +  KP + +   
Sbjct: 384 K------ADISGNDLLAWWETDERTRCIVLYIEDFGNPRTFARVARRVSATKPILVVKPE 437

Query: 288 --GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAE 345
             G +        V     LD    +  LL R    R       +  +  L +    A +
Sbjct: 438 REGRSRVEPDRPGV-----LDTEVAIDALLERTGVLRTQTLEELTELVRLLESQPLPAGD 492

Query: 346 AAGLLAGHLGVEA----DDTHQHGMMLDADSHQIIDLGDDFYTVGR----PHPMIDPTLR 397
              +LA   G               +   +   +  LG       R      P + P   
Sbjct: 493 RVAILANTQGPAPLVADAVLRAGLDLAPLEPATVERLGTLGRAAARNPLELGPGVVPADW 552

Query: 398 NQLIADLGAKPQVRVLLLDVVIG-FGATADP----------------------AASLVSA 434
            + +  L     V  +++  +    GA  DP                      AA +  A
Sbjct: 553 ERALELLLLDATVDAVIISFIPTVVGAPGDPRLLANPLPGGTLRGAPAQSLARAAEIADA 612

Query: 435 WQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAA 491
             K    R  ++P   +A        P+       T     I        A      
Sbjct: 613 VTKVATQRGRDRPKPVVANFLALPGVPERLGAGPRT-----IPSFDFPESAARALGH 664


>UniRef50_B9QZ08 CoA binding domain protein n=1 Tax=Labrenzia alexandrii DFL-11
           RepID=B9QZ08_9RHOB
          Length = 709

 Score =  184 bits (468), Expect = 5e-45,   Method: Composition-based stats.
 Identities = 68/520 (13%), Positives = 133/520 (25%), Gaps = 58/520 (11%)

Query: 66  VAIRSEAADAGIAQA---IMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VAI   + DA                  ++   +     +  ++ + S        + A+
Sbjct: 17  VAIIGASDDASRIGGRPVASTIAGGFKGRIYPVNPKRPTVQGLKAYPSITDVPEAVDCAI 76

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTL------EDEIQLKTRAREKGLLVMGPDC 175
           ++V      +             ++FS           E + ++   A+  G+ ++GP+C
Sbjct: 77  VAVPASLVEKTVADCAAMGTKSTIIFSSGFAELGAEGAETQQRIAAAAQNSGMRLIGPNC 136

Query: 176 GTSMIAGTP-------LAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
             +             +  +  +  G   +I  SG     +       G      +  G 
Sbjct: 137 IGAFSVSAGWFGTFSSVQASLRLAPGKTAIISQSGAYGAHMFYMAQRRGVATDLWVTTGN 196

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEA-VRLKIVNAMKATGKPTVALFL 287
                    I     +   +  +    +   ++   +       ++  +A  KP + + +
Sbjct: 197 E------SDIDVAEVIAYYAEHQDVSTIMAYTEGVKDRDRMCAALDLARAAKKPVIMIKV 250

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAA 347
           G T   A       AS   + A    L  +    R               TG        
Sbjct: 251 GDTDVGAEAAATHTASLAGDDAIYDALFKQYGVYRAHSCQEMVDVAYACQTG-------L 303

Query: 348 GLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGR----PHPMIDPTLRNQLIAD 403
                 + ++         M D      +++      + +      P         +   
Sbjct: 304 FPKGRKMAIQTVSGGIGIQMADESVKNGLEVPAMPEALQQKLLGLIPYAGVRNPIDITGQ 363

Query: 404 LGAKPQVRVLLLDVVIGFGATADPAASLVSA----------WQKACAARLDNQPLYAIAT 453
           +  +P+V    +D+ I        A  L SA           Q     R  +       +
Sbjct: 364 VLNQPEVIGQGIDLSIRESGCDAYATYLASAPQAPGLKDFCLQTFKDLREKHPETPMALS 423

Query: 454 VTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLS--PAAQQHTPSLLEN- 510
           +  T                  I        A    AAL          Q  TPS L   
Sbjct: 424 MIATPEIIADYEALN-------IGCFEDPVMAIRAMAALSQFYETFERGQPDTPSALPAG 476

Query: 511 -VAVIN--IGLRSFALELQSASKPVVHYQWSPVAGGNKKL 547
              V +  +        L SA  PV     +  A    K 
Sbjct: 477 VSEVPDRLVSEAGAKAILASAGIPVTRDVLTESAEEAVKA 516


>UniRef50_A3K489 CoA-binding protein n=1 Tax=Sagittula stellata E-37
           RepID=A3K489_9RHOB
          Length = 689

 Score =  184 bits (468), Expect = 5e-45,   Method: Composition-based stats.
 Identities = 73/509 (14%), Positives = 142/509 (27%), Gaps = 64/509 (12%)

Query: 66  VAIRSEAADA-GIAQAIMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +AI     D   I  +++  L+           S     + +              +L +
Sbjct: 7   IAIVGANDDPRTIGGSVLANLDAFGFTGDIHLVSRKKTRIGERSCLPDILSLPEGIDLLV 66

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEI------QLKTRAREKGLLVMGPDC 175
           + V     A+    ++ R +  V++FS       E       +L    RE  + ++GP+C
Sbjct: 67  LIVPKAAIADAIRDSIARKIGSVVVFSAGFAETGEEGRILQEELAALCREADMPMLGPNC 126

Query: 176 GTSMI--AGTPLAFANVMPE-----GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
              +    G P+ F  + P        +G+I  SG     + + +      ++  +  G 
Sbjct: 127 MGFINYKDGVPITFERMAPRALGTSKAVGIIAQSGATASNIRAAMHGRAIDVSCVVATGN 186

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK-IVNAMKATGKPTVALFL 287
                      A   +E +  D +  ++A   +      R   + +  +A G P V L  
Sbjct: 187 E------AQTGAEDYIEAMLDDPQIGLIAVYVEQIRNGPRFLDVAHRARAKGVPIVMLHP 240

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNA---------------IAPVSSGF 332
           G +   A        +     A +   +                          PV  G 
Sbjct: 241 GASDKGAEAALSHTGAMAGNHAAMRTAMRYAGVAIVETTEELFDVSAILLNWPTPVPGGV 300

Query: 333 ICGLYTG---GTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPH 389
                +G   G        +      +      +    +D ++   +D+G   +      
Sbjct: 301 GVISNSGAIRGLSFDFCEAIELPIAPLAQPTLDRLSAEIDGEASNPLDIGTTGFVR---- 356

Query: 390 PMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLY 449
               P +       +   P V V+L             A +L            D     
Sbjct: 357 ----PEIFGTSTQAMLDDPAVGVVL-------NCHVGGAPNLQIVKSDHLLPVFDTAQKP 405

Query: 450 AIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPS--L 507
            + T+ G + DP   +   A   D+GI    S   A      +       A   T     
Sbjct: 406 VVLTILG-DEDPLDPAFVKAV-RDSGIPFFRSPERALRAIRVVQKYADDLAALQTRKTPA 463

Query: 508 LENVAVINIG---LRSFALELQSASKPVV 533
           ++   +   G          L+     V 
Sbjct: 464 IKLPRLEGKGTIPEYRGKDFLRELGIGVP 492


>UniRef50_Q0A9U7 GCN5-related N-acetyltransferase n=2 Tax=Ectothiorhodospiraceae
           RepID=Q0A9U7_ALHEH
          Length = 887

 Score =  184 bits (468), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 72/500 (14%), Positives = 136/500 (27%), Gaps = 63/500 (12%)

Query: 65  CVAIRSEAADAGIAQAIMQQLEEALKQLAQGS--GSSQALTQVRRWDSACQKLPDANLAL 122
            +A+     D      +++ L  A  +          +AL  V  +          +LA+
Sbjct: 14  AIALIGTGGDTDSL--LLRNLVGAGFRGPVMPVMPGKRALHGVLCYPDVESLPMVPDLAV 71

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVT--------LEDEIQLKTRAREKGLLVMGPD 174
           + V      +      ++     +                    +   A+   L ++GP 
Sbjct: 72  LDVPFNRVPDAIRALGEKGTRAAVLVGKPAPNLSPEDYRAQIQAVLDAAKPFLLRLLGPG 131

Query: 175 CGTSMIAGTPLAFANVMPE---GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
           C    +  T +  +        G   ++  S              G G++H I LGG   
Sbjct: 132 CIDLTVPRTGVNASVAPFRPGAGRAALVTESAAVATRALDWCQSEGLGLSHLIHLGGAM- 190

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP 291
                 +     L+ L++D  S  +    +   +A +        A  KP V L      
Sbjct: 191 -----DVDTGDVLDYLASDVHSRAILLYLEYIDDARKFMSAARRAARVKPVVVLKPRRGS 245

Query: 292 AVARDENVWFA----SSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAA 347
             A ++ V+ A    + L   A L  L + V    +A  P   G +  L    +L   AA
Sbjct: 246 KGAAEDAVYEAAFRRAGLVRVADLDELFNAVEILTSARKPGRQGPLAVLGNSRSLGLLAA 305

Query: 348 GLL------AGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLI 401
             L         L  E+ +           +   +DLG D           D     + +
Sbjct: 306 NELEAYGGTLEGLSEESSEGLALLARDPESTANPLDLGGDA----------DADAYGKAL 355

Query: 402 ADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDP 461
             L    ++   L+                  A      A         +A  +G    P
Sbjct: 356 DTLAGDKRIGGTLVINQPNELVDNT-------AIVDVLEAHARKSRRAVLAVWSG----P 404

Query: 462 QCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA----------QQHTPSLLENV 511
           +  ++    L+   +       EA      L+                 +          
Sbjct: 405 RAGARGRERLKQT-MPAFEGPEEAVRAYMRLVQYQRNQELLMETPTSMPEAFETDPESAR 463

Query: 512 AVINIGLRSFALELQSASKP 531
            +I+  L +   +L      
Sbjct: 464 LLISAALTAGRDQLNEYQAQ 483


>UniRef50_Q65SV2 Succinyl-CoA ligase [ADP-forming] subunit alpha n=1 Tax=Mannheimia
           succiniciproducens MBEL55E RepID=Q65SV2_MANSM
          Length = 289

 Score =  184 bits (467), Expect = 8e-45,   Method: Composition-based stats.
 Identities = 40/256 (15%), Positives = 90/256 (35%), Gaps = 15/256 (5%)

Query: 89  LKQLAQGSGSSQALTQVRRWDSACQKLP--DANLALISVAGEYAAELANQALDRNLNVMM 146
           L               +  +++  + +    A   +I V   +  +   +A+   L +++
Sbjct: 35  LVGGVSPGKGGSIHLGLPVFNTVKEAVEQTGATATVIYVPAPFCKDAILEAIAAGLKLIV 94

Query: 147 -FSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG---TPLAFANVMPEGNIGVIGAS 202
             ++ +   D +Q+K +  E G++++GP+C   ++       +    +  +G +G++  S
Sbjct: 95  CITEGIPTLDMLQVKQKLDESGVVMIGPNCPGIIVPDECKIGIMPGYIHKKGRVGIVSRS 154

Query: 203 GTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKP 262
           GT   E   Q    G G +  +G+GG      + G + +  L++  AD K+E +  + + 
Sbjct: 155 GTLTYEAVKQTTDEGFGQSACVGIGGDP----IPGSNFIDILKLYQADPKTEAIVMIGEI 210

Query: 263 PAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSL----DEAARLACLLSRV 318
              A             KP V+   G T    +       + +      A      L   
Sbjct: 211 GGSAEEEAAEFIKAHVTKPVVSYIAGITAPKGKRMG-HAGAIISGGKGTADDKIAALQSA 269

Query: 319 TARRNAIAPVSSGFIC 334
                         + 
Sbjct: 270 GVICVKSLADIGAALK 285


>UniRef50_A9ISQ2 Acetyl-CoA synthetase n=4 Tax=Burkholderiales RepID=A9ISQ2_BORPD
          Length = 1113

 Score =  183 bits (465), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 90/519 (17%), Positives = 165/519 (31%), Gaps = 50/519 (9%)

Query: 66  VAIRSEAADAGIAQAI-MQQLEEALKQLAQGSGSSQA--LTQVRRWDSACQKLPDANLAL 122
           +AI   ++  G   A+ ++ L E          ++ A  +  +  + S        +LA+
Sbjct: 15  IAIVGASSQPGKVGAVPVRYLVEHGYHGEVYPINAGARQVQGLAAFASLRAVGRPIDLAI 74

Query: 123 ISVAGEYAAELANQALDRNLNVMM-FSDNVTLEDEIQLKTRAREK------GLLVMGPDC 175
            ++    A    + A+   +  ++ FS       E  +  ++         G+ V+GP+C
Sbjct: 75  FAIPASGADAALDDAIAAGVRNIVMFSAGFAELGEQGVAAQSAFAAKARAAGIRVLGPNC 134

Query: 176 GTSMI-------AGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
              M          +P+     +  G +G++  SG       +     G G++  +  G 
Sbjct: 135 LGFMNVARSVYATFSPVVSTGRVEAGPVGLVSQSGAFGAYAYAMARERGVGLSMWVTTGN 194

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK-IVNAMKATGKPTVALFL 287
                    I     +  ++ D  + V+    +   +  +L+  +   +A GKP VA+ +
Sbjct: 195 E------SDIDVADCIAWMARDPATRVIMAYLEGCRDGAKLRQALELARAAGKPVVAVKV 248

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAA 347
           G T   A+      A+   + A    L  +  A R             L   G  A    
Sbjct: 249 GRTALGAQAAASHTAALAGDDAVYQTLFRQHGAWRARTIEEFFDIAHCLAVSGRPANTRV 308

Query: 348 GLLAGHLGV------EADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPM-----IDPTL 396
           GLL    GV      +A +       L A +  II     F     P  +      DP+L
Sbjct: 309 GLLTVSGGVGVMMADDAAEAGLDVAELPAAAQAIIRARVPFAATQNPVDLTGQVTADPSL 368

Query: 397 RNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTG 456
                  +  +     LL+  +  FG+   PA   +         R     L   + +  
Sbjct: 369 LETAARAMLEQGGYGSLLI-FLAAFGS--TPAMQAMQQQLARDLRRDFPGRLVMFSALAD 425

Query: 457 TERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI----HPLSPAAQQHTPSLLENVA 512
                     Q   LE  G         A  + AAL         PAA+    +    + 
Sbjct: 426 AA--------QQRALEAQGCLCYGDPARAIRVLAALAFFHDRQQRPAAELAVAAPPVALR 477

Query: 513 VINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLL 551
                       L+ +  PV   + +       + AR L
Sbjct: 478 PGAYHEAEALQVLRDSGLPVTPARHAQSRDEALRHARAL 516


>UniRef50_A1BC12 CoA-binding domain protein n=1 Tax=Paracoccus denitrificans PD1222
           RepID=A1BC12_PARDP
          Length = 705

 Score =  183 bits (465), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 71/469 (15%), Positives = 150/469 (31%), Gaps = 41/469 (8%)

Query: 62  NDICVAIRSEAADAGIA-QAIMQQLEEALKQLAQGS--GSSQALTQVRRWDSACQKLPDA 118
           N   +A    +  A      +++ L +            S+  +  ++ + +        
Sbjct: 242 NPGAIAFVGASTSADKLGHHMIRNLVDFGFTGPIYPIHPSADEICGLKAYPTITDAPDGI 301

Query: 119 NLALISVAGEYAAELANQALDRNLNVM-MFSDNVTL------EDEIQLKTRAREKGLLVM 171
           + AL++VA     ++  +   + + +  + +           + E ++  +  +  + ++
Sbjct: 302 DRALVAVASHRVPDVLAECRAKGVKLAQVLTAGFAEFSSDSADLERRMLEQVADGAMRMV 361

Query: 172 GPDCGTSMIAG----TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLG 227
           GP+C  +  A        A  N    G I     SGT   ++  +  + G  +  A+  G
Sbjct: 362 GPNCIGTFSAASRMAVGAARYNPTEGGGITFFSQSGTFAGDVVRRAQVWGLPLGRALSCG 421

Query: 228 GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFL 287
                     +  +  L     D ++E++AF  +   +        A  A  KP V L  
Sbjct: 422 N------CSDVDMVDLLLQAEQDPETEIIAFYMESLRDPGLFFRAAAAMA--KPVVILRG 473

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAA 347
             T       +   A+   +       L++    + +        +  L   G    E  
Sbjct: 474 AQTEQGQVAASSHTAAMATDGLLWDAALAQSGVIQVSNVDDLMDTLLALAAHGRGPGERL 533

Query: 348 GLLAGHLGV---EADDTHQHGMML----DADSHQIIDLGDDFYTVGRPHPM-------ID 393
            +     GV    +D   + G+++     A    +   G    +V  P  +        D
Sbjct: 534 AIFGSGGGVSVTASDAAARAGLVVPALDPATEEGLRRFGIPGTSVANPIDIPVWGLRDGD 593

Query: 394 PTLRNQLIADLGAKPQVRVLLLDVVIGF-----GATADPAASLVSAWQKACAARLDNQPL 448
             +  ++I  L   P +  L++ V +G+      +      +L         AR D   +
Sbjct: 594 RYIFEEIINLLKDSPVIDRLVVFVEMGWVLDFMESDEAGLVALERICDSIARARPDGAAM 653

Query: 449 YAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLS 497
                 +G +        Q       GI+V  S   A    A LIH + 
Sbjct: 654 SLALRSSGDKYQDDFVRDQRRKFLKRGISVYQSTSRAVRAQARLIHGMR 702


>UniRef50_Q72GY5 6-carboxyhexanoate-CoA ligase n=3 Tax=Thermus RepID=Q72GY5_THET2
          Length = 745

 Score =  183 bits (463), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 75/455 (16%), Positives = 139/455 (30%), Gaps = 75/455 (16%)

Query: 66  VAIRSEAADAGIAQ------AIMQQLEEALKQLA-QGSGSSQALTQVRRWDSACQKLPDA 118
           VA+   + D            I  + +  +  +          +  +  +          
Sbjct: 208 VAVVGASRDPESIGYRVLENLIFGRFQGPVFPVNEAIGREGGTVGPLLAYPGLESVPGPV 267

Query: 119 NLALISVAGEYAAELANQALDRNLNV-MMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGT 177
           +L +++V  E   E    A  R     ++ +   T ++   L  +AR  G+ ++GP    
Sbjct: 268 DLVVVAVPKERVPEALEAAGRRGARGAIVLTTGFTPKEAQALADKARRLGMRLLGPGSLG 327

Query: 178 SMIAGTPLAFANVMPE----GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
            +     +  A  +      G + +   SGT  + + +     G G+   + LG +    
Sbjct: 328 LVHTHPGVRLAAGLAPLPKEGVLAISSQSGTLGRAVLAFAEEMGLGVASFVSLGAK---- 383

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTP-- 291
               IS+   L+    DE++ V+    +      R   +       KP +A+     P  
Sbjct: 384 --ADISSNDLLQFWEEDERTRVILLYLEHFGNPRRFSRLARRIGKKKPILAVHPSRDPLV 441

Query: 292 -AVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLL 350
            A+     V  A+SL+EA  +A LL++     N       G +  +      +  A   L
Sbjct: 442 RALFAQAGVVRANSLEEAFDVALLLAQGPLPEN-------GRVRLISNASGPSNLALEAL 494

Query: 351 AGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQV 410
                                  + +DLG             D     + +A+  A    
Sbjct: 495 KEGGMEV----------------EHVDLGSTA----------DLEAFRRALAEAEASDAG 528

Query: 411 RVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIAT 470
            V LL V +GF    +    L          R        +A + G        S   A 
Sbjct: 529 SVFLLFVPMGFAPEEEVLGLL----------REVRGGKTYLACLMG-------LSSGRAR 571

Query: 471 LEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTP 505
           +  + + V      A   A AL         +  P
Sbjct: 572 VLGS-VPVYRFPESA---AIALARAWGYRRWREEP 602


>UniRef50_UPI00016B24F6 succinyl-CoA synthetase, alpha subunit n=2 Tax=candidate division
           TM7 RepID=UPI00016B24F6
          Length = 286

 Score =  182 bits (462), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 44/270 (16%), Positives = 103/270 (38%), Gaps = 17/270 (6%)

Query: 66  VAIRSEAADAGIAQAI-MQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLP--DANLAL 122
           V I+      G   A  M   + ++      + +   +  V  + +          ++++
Sbjct: 11  VIIQGITGKNGRFHARNMLDYKTSIVAGTSPNQAISEVHGVPVFRTIDDIKKRFAIDISV 70

Query: 123 ISVAGEYAAELANQALDRNLNVMM-FSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           I V   +A     +A+   + +++  ++ V + D +++K +      +++GP+C   ++ 
Sbjct: 71  IFVPAPHAKAAILEAIQAQIPLIICITEGVPVHDMLEIKQKLHRSRSVLIGPNCPGVLLP 130

Query: 182 G---TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGI 238
           G     +  A++   G+  ++  SGT   E  S +  AG G  + IG+GG      + G 
Sbjct: 131 GRQLLGIIPASLAVPGDTAIVSRSGTLTYEAMSLLTQAGFGQRYIIGIGGDM----ISGS 186

Query: 239 SALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDEN 298
           S +  L++   D   + +  + +    +         ++  KP  A   G++        
Sbjct: 187 SFVDCLQLFQNDPSVKRIVMIGEIGGISEITAADYIKQSINKPVYAYIAGHSAPAGIQMG 246

Query: 299 VWFAS-----SLDEAARLACLLSRVTARRN 323
               +     +L+ AA     L +  A   
Sbjct: 247 -HTGAILGTNALESAATKTAYLQQAGAITA 275


>UniRef50_Q7VRY7 Acetyl-CoA synthetase n=3 Tax=Bordetella RepID=Q7VRY7_BORPE
          Length = 729

 Score =  182 bits (462), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 73/519 (14%), Positives = 149/519 (28%), Gaps = 46/519 (8%)

Query: 66  VAIRSEAADAGIAQAI---MQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   + D          + +       +   + +   +  +  +    +     +LA+
Sbjct: 25  VAVVGASDDPSKIGGRPLHLLKAARFALPIYPVNPARSVVQGLDAYARITETPTRPDLAI 84

Query: 123 ISVAGEYAAELANQALDRNLNVMMF--SDNVTLEDE-----IQLKTRAREKGLLVMGPDC 175
           ++V   +     +  +       +   S    +  E      +L  RAR  G+ V+GP+C
Sbjct: 85  VAVPAAHVLATFDDVVAAGARAAIVYTSGFAEIGAEGVKVQAELTARARASGVRVLGPNC 144

Query: 176 GTSMIAGTPL--AFANVM-----PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
              +   + L   F+  +       G+IG+   SG             G   +     G 
Sbjct: 145 LGVINTRSKLIATFSGAVGHAPPRPGSIGLASQSGALGAHCLVLAERRGIAFSVWATSGN 204

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEA-VRLKIVNAMKATGKPTVALFL 287
                    I     +  ++ D  + V+    +   +A   ++ +   +  GK  V + +
Sbjct: 205 E------SDIDVAELIAYMATDPGTHVIVACIEGVRDAGRLIEALELARTHGKQIVMMKV 258

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAA 347
           G +P  A       AS +        +L      R             L           
Sbjct: 259 GSSPIGAAAAASHTASMVGSDQVFDAVLREFGVYRAHSIEDMLDVAYALTVH-------Q 311

Query: 348 GLLAGHLGVEADDTHQHGMMLDADSHQIIDLGD-DFYTVGR---PHPMIDPTLRNQLIAD 403
                 L V         ++ D      +D+ +       R     P         + A 
Sbjct: 312 SPRGRSLAVVTTSGGVGVLLADEAERLGVDMPELPAIAQARIRELLPYAGTRNPVDVTAQ 371

Query: 404 LGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQC 463
           +   P++   +LD ++  G        L      A   R     L A++   G +    C
Sbjct: 372 ITNTPEILGPMLDALLASGTVGSLLLFLSHLGLNAAMMRRLMPALTALSKRPGPQVRVAC 431

Query: 464 R---SQQIATLEDAGIAVVSSLPEATLLAAALIHP----LSPAAQQHTPSLLENVAVINI 516
                +    LE  G +V      A    AAL+            +  P L +    +  
Sbjct: 432 LLACDEVRQELEALGFSVFEDPTRAIRTVAALMEIATAQAQARPARTLPRLPDTAHAVTP 491

Query: 517 GLRS----FALELQSASKPVVHYQWSPVAGGNKKLARLL 551
           G++         ++S     +  + +        +A  L
Sbjct: 492 GMQYSETEAKRLVRSIGIQTLPERIAQDPAQAAAIATEL 530


>UniRef50_C3XDZ9 Putative uncharacterized protein n=1 Tax=Helicobacter bilis ATCC
           43879 RepID=C3XDZ9_9HELI
          Length = 650

 Score =  182 bits (462), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 55/450 (12%), Positives = 133/450 (29%), Gaps = 53/450 (11%)

Query: 62  NDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
           N+  V + +          I +  +    +L   +     L   + + S  +   D + A
Sbjct: 231 NERVVIVGASTEKGKTGYTIAKNAQSFKGELLYVNAKGGELFGKKLYKSVSEIEGDIDTA 290

Query: 122 LISVAGEYAAELANQALDRNLN-VMMFSDNVTL----EDEIQLKTRAREKGLLVMGPDCG 176
           +I +  ++     ++ + + L  +++ +          +E ++   A      V+GP+C 
Sbjct: 291 VIVIGAKFVIPTIHELVKKGLKNLIIITAGFKESGHDAEEEEIGRLAATHNFNVIGPNCL 350

Query: 177 TSMIAGTPLAF---ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
                   L       ++ +G+   +  SG  +  L  + A  G G +H I +G      
Sbjct: 351 GFYANEEKLNITFGTGMVHDGSHAFVSQSGAVLASLMDRAAELGLGFSHLISVGN----- 405

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAV 293
               + +   + ML+  +  E +A   +    A    +  +++   KP        + A 
Sbjct: 406 -AVDLRSAEIIPMLNNAKSCESIALYLE--GVARGKSLCESIRNCNKPIYLFKAAKSEAA 462

Query: 294 ARDENVWFASSLDEAARLACLLSRVTA-----RRNAIAPVSSGFIC----GLYTG--GTL 342
            +       +     A    ++  +         + +       +         G  GT+
Sbjct: 463 KKAAFSHTGNLSGNYAMFNGIMQSLGVKVVNTLDSLLFAPLFKDVKNIAVITNAGGPGTV 522

Query: 343 AAEAAGLLAGHLGVEAD---DTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQ 399
             +A       L    D         +      +  ID+  D            P     
Sbjct: 523 LTDAIAARKKELYELNDAQKSELDSVLPPMWSHNNPIDVIGDAL----------PDRYES 572

Query: 400 LIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTER 459
            +  +   P + ++ +  +I      D         +        ++ +  +    G E 
Sbjct: 573 ALKIVDTFPNLDLIYM--LITPQDMTDALG----TVKILKQYTFKHKVVPIL---LGGEN 623

Query: 460 DPQCRSQQIATLEDAGIAVVSSLPEATLLA 489
                 +        GI   +S+ +A    
Sbjct: 624 ----VKEAREYCLKEGILYFTSIAQACEFL 649


>UniRef50_B0UL28 CoA-binding domain protein n=36 Tax=Proteobacteria
           RepID=B0UL28_METS4
          Length = 918

 Score =  182 bits (461), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 76/460 (16%), Positives = 124/460 (26%), Gaps = 39/460 (8%)

Query: 66  VAIRSEAADAGIAQA-IMQQLEEALKQLA--QGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   +   G   A I++ L EA         +     +  +    S       A+L +
Sbjct: 15  VALVGASERPGSFGAAILRNLREADFPGPIWPVNPRHDTVDGLPCHRSLEDLPEPADLVV 74

Query: 123 ISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAR----EKGLLVMGPDCGTS 178
           +    E    +   A  R     +         E  L   AR      GL ++GP+C   
Sbjct: 75  VVSPAESVPGVVAAAGARGCGGALIISAGLGAGEGSLAEAARLAGRAHGLRLLGPECMGL 134

Query: 179 MIAGTPLA---FANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREV 235
            +    L     A+  P G++ +I  S T    +    +  G G +  + +G      + 
Sbjct: 135 AVPAARLNASLLAHRPPRGDLALITQSRTVAAGIAEWASGRGYGFSGVLSVG------QA 188

Query: 236 GGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVAR 295
             +     L+  SAD  +  +    +   +A +        A  KP V L  G       
Sbjct: 189 VDVDIADCLDHFSADRGTRAILLHLETIRDAPKFMSAARAAARAKPVVVLRSGRHETARA 248

Query: 296 DEN--VWFASSLDEAARLACLLSRVTARRN--------------AIAPVSSGFICGLYTG 339
           D              A       R    R                  P     +  +  G
Sbjct: 249 DGRPVTHSGILAKPDAVYDAAFRRAGLLRVNALHEMFSAVETLGRQRPFPGKRLAIVTNG 308

Query: 340 GTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQ 399
             + A A   LA   G  A  +      LDA           +          D T    
Sbjct: 309 RGVGALAVDRLADLGGTLATLSPAAAERLDAALPPTGLPARPWANPLDLDADADGTRYAA 368

Query: 400 LIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTER 459
            +  L A  +   +L+  V     +   A +   A       +   +     A   G   
Sbjct: 369 ALDALIADRENDAVLVINVPT-ALSGGEAVAGAVAEAVRRGRKASLRAKPVFAVSVG--- 424

Query: 460 DPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPA 499
                      L  AGI    +  EA      L+      
Sbjct: 425 ---DSLAATEALGAAGIPRFPTDAEAVEGFMHLVRYREAQ 461


>UniRef50_Q7WEC6 Putative pimeloyl-CoA synthetase n=1 Tax=Bordetella bronchiseptica
           RepID=Q7WEC6_BORBR
          Length = 710

 Score =  181 bits (458), Expect = 8e-44,   Method: Composition-based stats.
 Identities = 74/473 (15%), Positives = 139/473 (29%), Gaps = 66/473 (13%)

Query: 66  VAIRSEAADAGIAQA---IMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VAI   +AD G               + +L   + +   +  V+ + S        +LA+
Sbjct: 32  VAIVGASADPGKIAGRPLAYMLSRGFVGKLFPVNPTRAQVQGVKSYPSLAAIGEPVDLAI 91

Query: 123 ISVAGEYAAELANQALDRNLNV-MMFSDNVTL------EDEIQLKTRAREKGLLVMGPDC 175
           +         +  + +   +   ++FS   +         + +L   AR  G+ ++GP+C
Sbjct: 92  VGTPAALVEGVIREGIAAGVRAFVVFSSGFSETGEAGAALQRRLGELARAHGVTILGPNC 151

Query: 176 GTSMIAGTPLAFA-------NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
                + T L  +         +  G   ++  SG            +G G +  I  G 
Sbjct: 152 LGVANSATGLIASFTTALEETPIRPGGFALVSQSGALGAYWMDICLRSGLGFSKWITTGN 211

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNA-MKATGKPTVALFL 287
                    + A  A+  L+ D  + V+    +   +    +         GKP +A+  
Sbjct: 212 E------CDMDAAAAIAYLAGDADTRVIGLYIEDIRDTAAFRRALRVAAEAGKPVIAIKA 265

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLY---------- 337
           G + A A        +   + A     L +  A R                         
Sbjct: 266 GRSQAGAAAAASHTGALAGDDALYDACLRQHGALRVDSLGEMMDAARLYLFDSVPQGRRV 325

Query: 338 --------TGGTLAAEAA--GLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGR 387
                    G  +A EA   GL    L           +     +   +DL  +      
Sbjct: 326 AVMSVSGGAGVLIADEAERRGLALPPLAGSTAAALAPVLPSFVQAANPLDLTGNV----- 380

Query: 388 PHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQP 447
              + D     + +  +   P    ++L V +          S+ SA+  A A       
Sbjct: 381 ---VQDTASIGRALEAVARDPGNDAIVLFVGL--------MHSIASAFTDAIAQARQRTH 429

Query: 448 LYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAA 500
              I    G +       + +A LE A I V   +P A     A +   +   
Sbjct: 430 RPIIVIWIGAK------EESVAALEQARIPVFRDIPPAVAAVGAAVRLRALRE 476


>UniRef50_Q89Y14 Bll0141 protein n=1 Tax=Bradyrhizobium japonicum RepID=Q89Y14_BRAJA
          Length = 704

 Score =  180 bits (456), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 72/537 (13%), Positives = 157/537 (29%), Gaps = 79/537 (14%)

Query: 66  VAIRSEAADAGIAQA---IMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   + D          M +  E   ++   + +   +  +  + S  +     +LA+
Sbjct: 14  IALIGASRDHEKIPGRLLAMLRKNEYPGKIYPVNPNYAEIDGLACYKSIAEIGAPIDLAV 73

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLE------DEIQLKTRAREKGLLVMGPDC 175
           + +          Q     +   ++ S     E       +  +   A+  G+ + GP+ 
Sbjct: 74  VIIPARAVLPALEQCAVAGVRNAVIISSGFAEEGGDSAAMQDAIAALAKRTGMRISGPNA 133

Query: 176 GTSMIA----GTPLAFANVMPEG---------NIGVIGASGTGIQELCSQIALAGEGITH 222
                         + A  +  G          IG++  SG        +    G  +++
Sbjct: 134 EGFFSQMQRVAATFSPAVDVKPGVVPLVATQRRIGIVAQSGGIGFAYYHRARALGVAVSY 193

Query: 223 AIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKA-TGKP 281
            +  G          + A   L+ L  D  ++V+    +   +  +        A   KP
Sbjct: 194 VVSAGNE------SDLGAGEFLDYLVQDSSTDVILLFIEGIRDVGKFLAAARRAAEVKKP 247

Query: 282 TVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVT---------------ARRNAIA 326
            +   +G + A  R      AS    +A    + ++                    +   
Sbjct: 248 VIVTKVGRSGAGQRAAASHTASMAGWSAAYDAVFAKYGFIVSNDLDEALTIAAVLASNPL 307

Query: 327 PVSSGFICGLYTG--GTLAAEAAGLLAGHLGVEADD---THQHGMMLDADSHQIIDLGDD 381
           P          +G  G   A+A  L    +   ++      +  M     +   ID+   
Sbjct: 308 PKGDRVAVVTVSGGAGIWGADAVALRGLQVPELSEPVQAEIKTLMPSYGTARNPIDVTAQ 367

Query: 382 FYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAA 441
             T G     +D          L A  +V  +L+ + +        +       ++    
Sbjct: 368 GVTSGGLQKSVD---------LLTASDEVDAILVVLSLS-------SEMRKPFREEELTP 411

Query: 442 RLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLS---- 497
            L  Q    +        D          L  +G+ V+S L  A +    L+        
Sbjct: 412 VLAAQHKPVLFYSYTVPSD-----FARRELAKSGVVVLSGLSHAGVAMRQLVDYARFELP 466

Query: 498 -PAAQQHTPSLLENVAVIN--IGLRSFALELQSASKPVVHYQWSPV-AGGNKKLARL 550
            PA +   PS   +  + +  +        L++A   +         AG ++ +AR+
Sbjct: 467 KPADEARLPSRDLSAHLTSPVLSEADSKALLRAAGIALPDEVLVKDKAGLDEAVARI 523


>UniRef50_Q2KUZ0 Putative acetyltransferase n=5 Tax=Bordetella RepID=Q2KUZ0_BORA1
          Length = 828

 Score =  179 bits (454), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 65/474 (13%), Positives = 123/474 (25%), Gaps = 54/474 (11%)

Query: 57  NNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLP 116
               P  + +     A     A +++     A   L           ++    +  ++  
Sbjct: 8   PLFEPRSLLIV----ADRTLPATSVLPGPLRARATLVDSPPGEA--PELPERCNGLEEGE 61

Query: 117 DANLALISVAGEYAAELANQALDRNLNVMMF-----SDNVTLEDEIQLKTRAREKGLLVM 171
             +LAL+ V+     E   +        ++       D          +  AR     ++
Sbjct: 62  RVDLALVCVSPAVLPETLRRLERLAPRALILLPHELPDPYPRGTLALCEEWARAHHCQLL 121

Query: 172 GPDCGTSMIAGTPLAFA---NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
           GP    +      L  +    +   G + ++  S + +  +         G + A+ LG 
Sbjct: 122 GPRAFGAQRPHAGLNLSQHPTLARAGRVALVAQSRSIMAAVMDWAEDVHIGFSLAVSLGD 181

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG 288
             +      +     L+ L++D +++ +    +    A          A+ KP + L  G
Sbjct: 182 EAV------LGMSEVLDYLASDPRTDSIVLYLEDMGPARDFMSALRAAASVKPVIVLKAG 235

Query: 289 YTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAG 348
                               A     L R  A R          +  L            
Sbjct: 236 RGEEGP------------ADAVFDAALRRAGAVRVRYFVQLFSAVKVLGYARRPRGRRVA 283

Query: 349 LLAGHLGVE--------ADDTHQHGMMLDADSHQIIDLGDDFYTVGRP---HPMIDPTLR 397
           LL+   G           D       +  A    +  L +       P   +  + P L 
Sbjct: 284 LLSNGSGPPQLALDLIGPDAAVLKADLSPATQRALAALLEPDAQTRNPVITYTPLTPELL 343

Query: 398 NQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGT 457
            QL+  L     V  +L  V++   A AD       A  +  A          ++   G 
Sbjct: 344 QQLLDCLIDDAGVDGVL--VLLAPDALADM-----PAVARQLAQLAPKARKPVVSCFMGD 396

Query: 458 ERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENV 511
                        L+DAG     +   A      L                E  
Sbjct: 397 A----GMRPLRRMLDDAGTPAFRTPESAADAFGVLATHYYNQQLLLQTQPPEAP 446


>UniRef50_B6JJ61 Acyl-CoA synthetase n=1 Tax=Oligotropha carboxidovorans OM5
           RepID=B6JJ61_OLICO
          Length = 457

 Score =  179 bits (453), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 62/466 (13%), Positives = 134/466 (28%), Gaps = 61/466 (13%)

Query: 66  VAIRSEAADAGIAQAIM-QQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +A+   + +   +  I+   L     +      +  +  +   + + S        +L  
Sbjct: 13  IAVIGASTNTAKSGGILFSNLVSGGFKGGLYPINPKATEILGCKAYPSLADVPEPVDLVY 72

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTL------EDEIQLKTRAREKGLLVMGPDC 175
           I +  ++      Q ++       + +             + +++   R+ GLL+ GP+ 
Sbjct: 73  IVLPSQHMESSIVQCVEAKAKAACIITAGFAEAGPEGIALQDKIREIGRKGGLLMAGPNT 132

Query: 176 GTSMIAGTPL--AFANVMP--EGNIGVIGASGTGIQELCSQIALAGE---GITHAIGLGG 228
              +     +  +F N     EG I +   +G     +  QI  +      I+ +I +G 
Sbjct: 133 IGMVNTDVRMMGSFVNFPRWEEGGISLFTQTGIFTGAVMRQIMDSDVQRPPISKSIDVGN 192

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLG 288
           +        +  L  L     DE ++V+ F  +   +           +  KP V L  G
Sbjct: 193 K------IDVDELDFLHFAEKDEGTKVIGFYIESIRDLPGFAAKVKEISRTKPVVMLKPG 246

Query: 289 YTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGL------------ 336
            T            S   +   +   L      R          +  L            
Sbjct: 247 RTAFGKMASACHTGSPPSDDTEVTAALKGSGILRVDDEEEFVNVLRALAYLPRPKGRRLG 306

Query: 337 ---YTG--GTLAAEAAGLLAGHLGVEADDTHQH---GMMLDADSHQIIDLGDDFYTVGRP 388
               +G  G +A++ A      L   ++ T             +    D        G  
Sbjct: 307 IATTSGALGVIASDYASDFGFELAQYSEATLNKMETVFPDWLRAANPFDFWIGIDVKGP- 365

Query: 389 HPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPL 448
                       +    A P V ++L  ++    A      +L+   ++        +P+
Sbjct: 366 -----REAHEIGLEAAFADPNVDLVLCTLLAPPNADFPEMGALLRRLRETYD-----KPV 415

Query: 449 YAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH 494
             +   +   R  Q           AGI V S++       + +  
Sbjct: 416 ALVLYGSAAARWTQEIEG-------AGIPVFSNVRAGVRTLSLIAQ 454


>UniRef50_Q46RU5 CoA-binding n=4 Tax=Betaproteobacteria RepID=Q46RU5_RALEJ
          Length = 741

 Score =  178 bits (452), Expect = 4e-43,   Method: Composition-based stats.
 Identities = 78/489 (15%), Positives = 144/489 (29%), Gaps = 64/489 (13%)

Query: 66  VAIRSEAADAGIAQA-IMQQLEEALKQLAQ--GSGSSQALTQVRRWDSACQKLPDANLAL 122
           VAI   +AD       ++  LE      A    S SS  +       S  +     +LA+
Sbjct: 52  VAIVGASADPRSFGGFVLANLERFGYAGAIHLVSRSSTEINGRACVKSVDEVPAGIDLAV 111

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDC 175
           +++      +       +     +        +     E + QL   AR+ G+L++GP+C
Sbjct: 112 LAIPEAGVLDAVRSLAAKGTRAAVLFASGYAETGEAGRERQDQLAAAARDAGMLLLGPNC 171

Query: 176 GTSMI--AGTPLAFANVMP-----EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
                     P+ F  V P        IGV+  SG     +       G  +T  +  G 
Sbjct: 172 MGFTNFEGNVPVTFEAVQPYPCSGRPGIGVVAQSGAMAANMRDAFVGRGLPLTAVVSTGN 231

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNA-MKATGKPTVALFL 287
                    + A   +     D ++ VLA  ++          +    +  GKP V L  
Sbjct: 232 E------ASLGAEDFVAHYIDDPQTRVLAVYAEQVRRPRTFLALARKAREAGKPIVMLMP 285

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLY------TGGT 341
           G +            +   + A     L+R                  L        GG 
Sbjct: 286 GRSERAREAAQSHTGALAGDHATACVALAREAVVLVDTPDELVDAAAILLRFPVPPAGGP 345

Query: 342 LAA--------------EAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGR 387
                            +  GL    LG +   + +  +   A +   +D          
Sbjct: 346 AFMTGSGAMKNVALDFCDGLGLELPPLGAQTTASLKAMLPDYAVAENPLD--------YT 397

Query: 388 PHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFG-ATADPAASLVSAWQKACAARLDNQ 446
              +  P L  +++  + + P V  ++L +  G   A  D A  +V A  +A       +
Sbjct: 398 TIGVRQPGLVGEVLLTMLSDPAVGSIVLSIPAGPEVAQRDKAEHIVPALARA------GK 451

Query: 447 PLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAAL-IHPLSPAAQQHTP 505
           P   + T      +P         +  +G+    S   A    A +  +  +        
Sbjct: 452 PAVLVVTGDSGPIEPFFVD----AIRASGVPFFRSPDRALRALARVSAYGEALQRAGRAT 507

Query: 506 SLLENVAVI 514
             +     +
Sbjct: 508 QSIPAAVPL 516


>UniRef50_B7UXS6 Pimeloyl-CoA synthetase n=13 Tax=cellular organisms
           RepID=B7UXS6_PSEA8
          Length = 715

 Score =  178 bits (452), Expect = 4e-43,   Method: Composition-based stats.
 Identities = 67/518 (12%), Positives = 142/518 (27%), Gaps = 45/518 (8%)

Query: 66  VAIRSEAADAGIAQA---IMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           VA+   ++D                   Q+   + +   +  +  + S  +     + A+
Sbjct: 27  VAVIGASSDPTRIGGRPIAYMLRHGYAGQILPVNPNRAEIQGLPAFASVAELPQAPDAAI 86

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEI------QLKTRAREKGLLVMGPDC 175
           ++V      E       +     ++FS   +   E        +   ARE G+ ++GP+ 
Sbjct: 87  VAVPAPQVLETVRALGRQGARSAIVFSSGFSEVGEAGAAMQDAVVAAAREYGMRLLGPNA 146

Query: 176 GTSMIAGTPLAFA-------NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
             +  +               V   G +G+   SG     L         G    +  G 
Sbjct: 147 LGAFNSNLGYYAFFSTSLERGVPLPGRVGIATQSGAYGAHLLGMARQCRLGTPICVATGN 206

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIV-NAMKATGKPTVALFL 287
                    ++   ++  L    + +V+   ++             A    GKP +   +
Sbjct: 207 E------ADVTLGDSIGWLVESPEIDVVMAYAESIRNVDSFLAALEAAHRAGKPVILHKV 260

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFI-----CGLYTGGTL 342
           G +   +R      AS   +   L  +L      R                     G +L
Sbjct: 261 GRSALGSRAALSHTASLAGDDKVLDAVLGDYAVIRARTTEELMDIAYLATRRIYPVGNSL 320

Query: 343 AAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIA 402
                 +  G   + +D   + G+ +        +      +   P   +D T +     
Sbjct: 321 GM--ITVSGGAGIIVSDVAEEVGLPMPPMPDMAQERLKARLSFASPINPVDCTAQALNDL 378

Query: 403 DLGAKPQVRVLLLDV---VIGFGATADPAASLVSAWQKA-CAARLDNQPLYAIATVTGTE 458
            L       +++      ++ F   A  AAS+ +   +     +  +     + +V G  
Sbjct: 379 TLVRDFTESMVVDGGYRSLLAFFTQAGTAASIGARLAEQFRRIKEAHPERLFVVSVMGEG 438

Query: 459 RDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQ---HTPSLLENVAVIN 515
            +           E+AG A+      A +   A+       A+      P+    +    
Sbjct: 439 EELAPY-------EEAGFALFEDPTRAVVAIQAMGRLGEAFARPLRLRRPAGGLQLPAST 491

Query: 516 IGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLER 553
            G       L  A            A      A  +  
Sbjct: 492 PGEAEAKRLLARAGIESAAEAVLGSAEEAVAFAEGIGY 529


>UniRef50_B9L969 CoA binding domain protein n=2 Tax=Epsilonproteobacteria
           RepID=B9L969_NAUPA
          Length = 634

 Score =  177 bits (449), Expect = 8e-43,   Method: Composition-based stats.
 Identities = 58/446 (13%), Positives = 127/446 (28%), Gaps = 60/446 (13%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
           VAI            AI +   ++  ++   +   + L   + +      LP  + A+I+
Sbjct: 227 VAIIGATDKKEKVGYAIAKNALKSKAKIYFVNPKLKKLFSKKVYT--LDTLPQVDTAVIA 284

Query: 125 VAGEYAAELANQALDRNLNV-MMFSDNVTLE----DEIQLKTRAREKGLLVMGPDCGTSM 179
           +   Y  E   +   +     ++ S           E++LK  A+E  + ++GP+C    
Sbjct: 285 IPSVYVIESVKKLAKKGCKNFIIISAGFKESGNTSAELELKELAKEHNINIIGPNCLGIY 344

Query: 180 IAGTPLAFANVMPE---GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVG 236
                L           G+IG++  SG  +  L  + +    G +H I +G       + 
Sbjct: 345 NDTLKLNLTFAKSRIYSGSIGLVSQSGAVLTALLDKASHYKTGFSHIISMGN------MA 398

Query: 237 GISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARD 296
             +   A+  L+  +  + ++  ++             ++   KP +    G +    + 
Sbjct: 399 DFNFAHAVNELNRQKNCKTISIYAEGLQFGKEFLKA--IRNLQKPVLLFKSGKSKEAKKA 456

Query: 297 ENVWFASSLDE-----AARLACLLSRVTARRNAIAPVS----SGFICGLYTGGTLAAEAA 347
                 +         +   +       +  + I           I     GG  A    
Sbjct: 457 AFSHTGNIAGNYEMIISLSKSAGAVIKDSIESLIYAPQFQNVKEVIIVTNAGGPGAILTD 516

Query: 348 GLLAGH----LGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIAD 403
            +        L         H +      +  ID+  D             + R      
Sbjct: 517 LVSGKKHLATLDSSTLSALNHVLPSTWSHNNPIDIIGDAT-----------SKRYNDTLK 565

Query: 404 LGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQC 463
           +         L+ V++      D +  +     K   A                    + 
Sbjct: 566 IIHDKAD---LIYVIVTPQFMTD-SEEIAKILIKYEKAVPIFLGK-------------RS 608

Query: 464 RSQQIATLEDAGIAVVSSLPEATLLA 489
             +    L  +     +SL EA+ + 
Sbjct: 609 FIKACKILNKSRKLYFTSLEEASKIL 634


>UniRef50_P53595 Malate--CoA ligase subunit alpha n=184 Tax=cellular organisms
           RepID=MTKB_METEA
          Length = 296

 Score =  177 bits (449), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 56/281 (19%), Positives = 104/281 (37%), Gaps = 19/281 (6%)

Query: 66  VAIRSEAADAGIAQA----IMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLA 121
           + ++    D G   A                 +G  +   +        A +    A  +
Sbjct: 11  ILVQGITGDKGTFHAKEMIAYGSNVVGGVTPGKGGKTHCGVPVFNTVKEAVEA-TGATTS 69

Query: 122 LISVAGEYAAELANQALDRNLNVMM-FSDNVTLEDEIQLKTRAREK----GLLVMGPDCG 176
           +  VA  +AA+   +A D  L ++   +D +  +D +++K   R        +V+GP+C 
Sbjct: 70  ITFVAPPFAADAIMEAADAGLKLVCSITDGIPAQDMMRVKRYLRRYPKEKRTMVVGPNCA 129

Query: 177 TSMIAG---TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSR 233
             +  G     +   ++   G +GVI  SGT   E  +Q+   G GI+ ++G+GG  ++ 
Sbjct: 130 GIISPGKSMLGIMPGHIYLPGKVGVISRSGTLGYEAAAQMKELGIGISTSVGIGGDPIN- 188

Query: 234 EVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAV 293
              G S L  L +   D ++E +  + +              +   KP +    G T   
Sbjct: 189 ---GSSFLDHLALFEQDPETEAVLMIGEIGGPQEAEASAWIKENFSKPVIGFVAGLTAPK 245

Query: 294 ARDENVWFA--SSLDEAARLACLLSRVTARRNAIAPVSSGF 332
            R      A  S+  ++A     + R      A  P S G 
Sbjct: 246 GRRMGHAGAIISATGDSAAEKAEIMRSYGLTVAPDPGSFGS 286


>UniRef50_Q0K4B6 Acyl-CoA synthetase n=5 Tax=Burkholderiales RepID=Q0K4B6_RALEH
          Length = 721

 Score =  177 bits (448), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 63/493 (12%), Positives = 142/493 (28%), Gaps = 65/493 (13%)

Query: 47  DTTGFWHDDFNN-ATPNDICVAIRSEAADAGIAQAI--MQQLEEALKQLAQGSGSSQALT 103
           +  G W  D      P  I +   SE  D+  A+    +    +   +L   +   + ++
Sbjct: 6   EANGLWFSDLTRLVEPRSIVLVGASEKPDSIGARTFENLTVYSQFQGELYLVNPGRKEIS 65

Query: 104 QVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLN-VMMFSDNVTL------EDE 156
               + S        +LA+++V  +   +   +  +  +   ++F+             E
Sbjct: 66  GRPCYPSVRDLDAVPDLAIVAVRADMVLDALRECGECGVKFAIVFTSGFGETGEEGRAAE 125

Query: 157 IQLKTRAREKGLLVMGPDC--GTSMIAGTPLAFANV-----MPEGNIGVIGASGTGIQEL 209
            +++    + G+ + GP+C    +M A   + F+          G IGV    G   +  
Sbjct: 126 AEMRAIVAKTGMRIYGPNCPGLNNMNARLGMTFSPAWRIDNARPGPIGVATQGGGLGRSF 185

Query: 210 CSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRL 269
              +   G GI      G          +     +  ++     +V+    +      R 
Sbjct: 186 IQSMDR-GVGIGLWCSGGNE------ADLEVSDYIHYMADAPDIKVIVTTLEGVRNGPRF 238

Query: 270 KIVN-AMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPV 328
                     GKP VAL +G +   A+      A+    A   + +  ++          
Sbjct: 239 MAAALHSARRGKPIVALKVGKSEIGAKAAASHTAAIAGVAEINSAVFRQLGIIEVDDIDE 298

Query: 329 SSGFICGL---------------YTGGT--LAAEAAGLLAGHL---GVEADDTHQHGMML 368
                  L               ++GGT  L  +  G+    L     +  +     +  
Sbjct: 299 LIDVASLLSRATPTGKEQLAVYSFSGGTAALCTDMVGIAGLTLSKFAPQTLEALARALPG 358

Query: 369 DADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPA 428
            A     +D+  +                   +      P   ++L+ + + +G T+   
Sbjct: 359 YAAFDNPVDVTAEVLVNAEVG--------YAALKATAGDPNTDLVLVPIPVEYGKTSAM- 409

Query: 429 ASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLL 488
                    +       +    +              +    + + G+  + ++  A L 
Sbjct: 410 ------LADSMVRVQSEEATPIVPVWM-----SDRTGEGQRKMIEGGLMPMRAVGNAVLA 458

Query: 489 AAALIHPLSPAAQ 501
               I      AQ
Sbjct: 459 VKRFIEYGKWQAQ 471


>UniRef50_Q7W1M6 Putative acetyl-CoA synthetase n=2 Tax=Bordetella
           RepID=Q7W1M6_BORPA
          Length = 480

 Score =  177 bits (448), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 62/455 (13%), Positives = 136/455 (29%), Gaps = 41/455 (9%)

Query: 66  VAIRSEAADAGIAQA-IMQQLEEALKQLAQGSGSSQALT---------QVRRWDSACQKL 115
           VA+   +AD       I++ + +              +          +VR   +  +  
Sbjct: 32  VAVVGISADHAKLGNVILRNVVKNGFAGNIYGVCRAPVEPGVFEAGYERVRFVQAFSEIE 91

Query: 116 PDANLALISVAGEYAAELANQ--ALDRNLNVMMFSDNVTLED-----EIQLKTRAREKGL 168
              ++AL +V  +               L V++ S      +     E  L+    E  L
Sbjct: 92  EPVDVALFAVPADMVVTALASVPLGRLRLAVILASGFTETGERGALLETALRQYCLETQL 151

Query: 169 LVMGPDCGTSMIAGTPLAFA-----NVMPEGNIGVIGASGTGIQELCSQIALAGEGITHA 223
            V+GP+C   ++ G  L        N M EG + ++  SG     + + +   G G+   
Sbjct: 152 PVVGPNCQGVVVPGVKLQMTFSPMYNRMLEGKVAIVSQSGAMAGYMANNLMRRGVGLCCV 211

Query: 224 IGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTV 283
           +  G   +      ++A   +  L+   +  V+    +                  +  V
Sbjct: 212 VSSGNEAV------LTAADYIHALADKPECRVVLCYIEQIKNGRHFARSVQRLGPQQRIV 265

Query: 284 ALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLA 343
            +  G + A     +    +   +   +  +  ++   R   +  +      L  G  + 
Sbjct: 266 VVKSGRSTAGVAAASSHTGAMASDDRVIDGVFRQLGVVRARDSATAIDVAMALANGRRMK 325

Query: 344 AEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTV--GRPHPMIDPTLRNQLI 401
             A G+L+   G+      +   +L+ D   +     D       +            L 
Sbjct: 326 GGAVGILSVAGGL----AVELSDLLEMDGFTVPRFDPDTLERLKAKVPEFGASRNPIDLS 381

Query: 402 ADLGAKPQVRVLLLDVVIGFGATADPAASLV----SAWQKACAARLDNQPLYAIATVTGT 457
             +  +  +   +L++          A         A+  A      +     +   TGT
Sbjct: 382 GAILTQESLFEEVLNLFARARNLDGFAIISTFIRNPAFAHAIVRMYRSTDKPVVVCWTGT 441

Query: 458 ERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAAL 492
              P+   + +  L  +GI +        L   A+
Sbjct: 442 ---PEQTPESLEILTRSGIPIYGDTGRVALALRAI 473


>UniRef50_Q46QN5 CoA-binding n=3 Tax=Burkholderiales RepID=Q46QN5_RALEJ
          Length = 711

 Score =  177 bits (448), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 56/455 (12%), Positives = 124/455 (27%), Gaps = 45/455 (9%)

Query: 66  VAIRSEAADAGIAQA-IMQQLEEALKQL--AQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +AI   + D        +  L+    +      +     +  +  +          ++A+
Sbjct: 24  IAIIGASRDTSRIGGVALDHLQRLGYRGTVYPVNPRYAEIAGLACYPDVESLPKTPDVAV 83

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKTRAREKGLLVMGPDC 175
           +++  +       +     +   +        +    +  + +L   ARE G+ + GP+C
Sbjct: 84  LALGADDVLPQMRRCHAVGIRAAILYASGFAEAGEAGIALQAELTAFARETGMAIAGPNC 143

Query: 176 GTSMIAGTP--LAFANVMP-------EGNIGVIGASGTGIQELCSQIALAGEGITHAIGL 226
                  T    AFA            G++ ++  SG     + +       G    I  
Sbjct: 144 MGLANLTTRAITAFATTFRAYPPQDGPGHVSLLTQSGNVCAIVYATGRQMDVGFHQFINT 203

Query: 227 GGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK-IVNAMKATGKPTVAL 285
           G          +     L+ L+ D ++  +    +      R       ++A GKP + L
Sbjct: 204 GNEAC------LDYADYLDYLADDAQTGAVVGYVEGLRNGPRFIDAAARLRAAGKPLIVL 257

Query: 286 FLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFI-----CGLYTGG 340
             G + A +       A      A      ++V A +       +             G 
Sbjct: 258 KAGESEAGSSATQSHTAVLAGNQAIYRAAFAQVGAMQARDPAHLTDLAYLSGFRQRSAGR 317

Query: 341 TLAAEAAGLLAGHLGVEADDTHQHGMMLDADS--HQIIDLGDDFYTVGRPHPMIDPTLRN 398
            +   +     G L  +        +   +++   ++     +   V  P  M       
Sbjct: 318 RVVVASVSGAMGALSADLLSAAGLDVPRLSEAVQQRLQTAVPEIGGVANPVDMTGQLFNR 377

Query: 399 QLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTE 458
             +A             DV+  +       A L+                  +   TG  
Sbjct: 378 NGLAYAVLDNLADDDGTDVIFIYAT-----AYLLDRVADELIEVAAKTNRLIVVATTGEP 432

Query: 459 RDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALI 493
                       L +AG+A+   +  A       +
Sbjct: 433 T-------SRQRLAEAGVALFPDVARAAQALGTYV 460


>UniRef50_D1A3H7 CoA-binding domain protein n=3 Tax=Actinomycetales
           RepID=D1A3H7_THECD
          Length = 887

 Score =  176 bits (447), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 73/531 (13%), Positives = 140/531 (26%), Gaps = 85/531 (16%)

Query: 67  AIRSEAADAGIAQAIMQQ---LEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALI 123
            +   +         + +      A    A    + + L  VR   S  +     +LA++
Sbjct: 207 VVVGASRRRRSVGNALLRRLHAAAAFPVYAVNPRAGRELEGVRCVPSVAELPEPPDLAVL 266

Query: 124 SVAGEYAAELANQALDRNLNV-MMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG 182
           +V      + A +   R     ++ S  +T     +L       G+ ++GP+C      G
Sbjct: 267 TVPAHIVPQAAEECGRRGARALVVISSGLTEPQARRLLEACHRYGMRLVGPNCIGVADPG 326

Query: 183 TPLAFANV---MPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGIS 239
             L           G  GV+  SG     L   ++  G GI+    +G +        +S
Sbjct: 327 AGLDATFTPRDPRPGTAGVVVQSGGVGIALQDHLSRLGIGISSFASVGDKL------DVS 380

Query: 240 ALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVAR---- 295
           A   L    +D  + +     +      +            P + +  G + A  R    
Sbjct: 381 ANDMLMWWESDGVTRLGVLHLESFGNPRKFARTARRVGRKMPLLTVIAGRSQAGRRAAAS 440

Query: 296 -----------------DENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYT 338
                               +     L E    A LL+     R +   + +        
Sbjct: 441 HTAAVATPEVTRRALFAQAGIVATDDLGELVDAAALLAHQPYPRGSKVAIVTNA----GG 496

Query: 339 GGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRN 398
            G LAA+A       +   +  T +    L  +   + +  D           + P    
Sbjct: 497 AGVLAADACTERGLIVAELSASTRRRLRQLLPEGASLDNPVDATAA-------VPPRAFR 549

Query: 399 QLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTE 458
             +A + A   V  ++              A  V       AA         +A   G  
Sbjct: 550 AALAAVAADEGVDAVM--------------AVAVPTAVGRPAAVAGCGGKPLVAVTLGQA 595

Query: 459 RDPQCRSQQIATLEDAGIAVVSSLPE----ATLLAAALIHPLSPAAQQHTPSLLENVAVI 514
                       +   G+   +            A+       P   +   + L+     
Sbjct: 596 ETVT--------VNRDGVPSYAYPENAAAALAHAASYGRRRSRPQGTEPVFTDLDRERAD 647

Query: 515 NIGLRSFA--------------LELQSASKPVVHYQWSPVAGGNKKLARLL 551
            I                      L++   P+  ++W+         AR L
Sbjct: 648 RIVGGFLKRCPDGGWLPPDQAMELLEAYRLPMAPWRWARTEEEAVAAARKL 698


>UniRef50_Q3ADM2 Succinyl-CoA ligase [ADP-forming] subunit alpha n=5 Tax=cellular
           organisms RepID=Q3ADM2_CARHZ
          Length = 289

 Score =  176 bits (447), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 42/248 (16%), Positives = 102/248 (41%), Gaps = 13/248 (5%)

Query: 66  VAIRSEAADAGIAQAI-MQQLEEALKQLAQGSGSSQALTQVRRWDSACQKL--PDANLAL 122
           + ++    + G      M +    +            +  V  +++    +    AN ++
Sbjct: 11  IVVQGITGNQGRFHTGKMLEYGSKVVAGVSPGKGGTEVLGVPVFNTVLDAVKNTGANTSI 70

Query: 123 ISVAGEYAAELANQALDRNLN-VMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIA 181
           + +   +  + A +A++  +  +++ S++V L D +++   A   G+ V+GP+    +  
Sbjct: 71  LFIPAPFVLDAALEAMEAGIKTIVIISEHVPLHDALKIMRVAEAYGVTVVGPNTFGVISP 130

Query: 182 G---TPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGI 238
           G     +    +  +G +G++  SGT   ++  ++  AG G +  +GLGG      + G+
Sbjct: 131 GIAKVGIMPNTIYQKGPVGIVARSGTLSYQIAYELTRAGLGQSTVVGLGGD----RIVGL 186

Query: 239 SALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDEN 298
           S    +  L+ DE+++ +  V +    A        ++   KP VA   G T    +   
Sbjct: 187 SLAEVILSLARDEETQGIVVVGEIGGTAEEE-AAEVIRHINKPVVAFIAGKTAPPGKRMG 245

Query: 299 VWFASSLD 306
               + ++
Sbjct: 246 -HAGAIIE 252


>UniRef50_Q13PC5 Putative acyl-CoA synthetase n=2 Tax=Burkholderia xenovorans LB400
           RepID=Q13PC5_BURXL
          Length = 718

 Score =  175 bits (444), Expect = 4e-42,   Method: Composition-based stats.
 Identities = 81/540 (15%), Positives = 158/540 (29%), Gaps = 68/540 (12%)

Query: 62  NDICVAIRSEAADA-GIAQAIMQQLEEALKQLAQGSGSS--QALTQVRRWDSACQKLPDA 118
           N   VA+   + D       +++ L     +    + +   + L  V  +          
Sbjct: 15  NPASVAVIGASEDQHKYGGRLLKMLLSHGYRGHIMAINPVRETLLGVSAYPHIDVTPVVP 74

Query: 119 NLALISVAGEYAAELANQALDRNLNVMM-----FSDNVTLE--DEIQLKTRAREKGLLVM 171
           ++A++++      E       R +   +     FSD        E  + + AR   + ++
Sbjct: 75  DVAVMAIPQPKVREAIEACAARGVTAAIVITARFSDGGAEGAVLERDIVSIARSANMRLV 134

Query: 172 GPDCGTSMIAGTPLAF-------ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           GP+C   +     +         A  +P G +G +  SG  +  +  +    G   +HAI
Sbjct: 135 GPNCLGIISPAHRVVLCPSTALVAEGLPVGRVGFVSQSGALMGTIFDKAKEIGLAFSHAI 194

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMK-ATGKPTV 283
            +G +        +     +E L  D  + V+    +   +  R   + A     GKP +
Sbjct: 195 SVGNQ------ADLELCDFVEYLIGDPATAVICTYIEGLKDPRRFAELAARAREAGKPWL 248

Query: 284 ALFLGYTPAVARDENVWFASSLDEAARLACLLSR---------------VTARRNAIAPV 328
           A+  G T A A+      AS   + A    +                   T+  +  A  
Sbjct: 249 AVSSGRTQAGAQAAFSHTASVAGDRAVFEAVCREEHVTLLDSPLTMIALATSLADHPATQ 308

Query: 329 SSGFICGLYTGG--TLAAEAAGLLAGHLGVEADDTHQHGMM--LDADSHQIIDLGDDFYT 384
            S       +GG   +AA+        + V +D T          + +   +D G     
Sbjct: 309 VSRIAVFSPSGGEAAIAADEIESAGLRMAVFSDATRTKLADYYPPSQAANPVDTGGRTVG 368

Query: 385 VGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLD 444
            G       P +  +    +   P    LL  +          A+ +  A +        
Sbjct: 369 DG-------PDVVGESARIVADDPDTDALLFAITTTPTLH-RVASDVADALR--RDPASP 418

Query: 445 NQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLS--PAAQQ 502
                 +          +        L + G   +++L EA  + AA     S  P  + 
Sbjct: 419 TPRKPILYVF----ETGRLADTARRGLLERGRYFLNNLREAVDVLAAWHSRGSYLPPGRP 474

Query: 503 HTPSLLENVAV---------INIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLER 553
             P+     A             G  +    L          + +        +A  L  
Sbjct: 475 VRPADCPLTAAGCAAHLPGKGTYGEGATREWLGRYGVRTNEERLARDEDEAVAIAGELGY 534


>UniRef50_B2JRL3 CoA-binding domain protein n=1 Tax=Burkholderia phymatum STM815
           RepID=B2JRL3_BURP8
          Length = 718

 Score =  175 bits (443), Expect = 4e-42,   Method: Composition-based stats.
 Identities = 80/545 (14%), Positives = 162/545 (29%), Gaps = 68/545 (12%)

Query: 52  WHDDFNNATPNDICVAIRSEAADAGIAQ-AIMQQLEEALKQLAQGS--GSSQALTQVRRW 108
            H       PN   +A+   +  A      +++ L+      A       +  +  +  +
Sbjct: 1   MHPLSPLLNPNS--IAVLGASPRAEALGNTVIRNLQRIGYAGAIYPVHPGAPEVLGIPAY 58

Query: 109 DSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMF-------SDNVTLEDEIQLKT 161
            +        + A+I+++ + A         R +   +        +       + +L  
Sbjct: 59  ANLDDIPGSVDCAVIALSYDKALPALEALNARGVRNAVLYASGFAETGAEGAALQEELTR 118

Query: 162 RAREKGLLVMGPDCGTSMIAGTPLAFANV-----MPEGNIGVIGASGTGIQELCSQIALA 216
              + G+ + GP+C       + ++  +      +  G + ++  SG+    L +     
Sbjct: 119 YCNQNGINLCGPNCLGLYSVASRVSLYSAALPENLRPGGLALLSHSGSACIALSNLDR-- 176

Query: 217 GEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAM- 275
             G +H + LG   +            L+ ++ DE + V A   +   +  +  +     
Sbjct: 177 -LGFSHLVSLGNGAV------TDIADYLDYVAQDEHTTVAALFIETLRDPEKFAVAARKM 229

Query: 276 KATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTA--------------- 320
           +A GKP VAL +G + + A        +       L     R+                 
Sbjct: 230 RAAGKPVVALKVGRSSSGAAASAAHTGALATPDTALQAFFHRLGVVLVEDYDELIETCVL 289

Query: 321 -RRNAIAPVSSGFICGLYTGGTLA-----AEAAGLLAGHLGVEADDTHQHGMMLDADSHQ 374
              N   P S+G      +GG LA     AE  GL    L     +  +  +        
Sbjct: 290 FLGNDRKPKSNGVAVLNVSGGELALTCDIAERVGLTLPDLAPATVNLLREILPPFGAPRN 349

Query: 375 IIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSA 434
            +D             + D  +    +  L A P + ++ +          D AA+    
Sbjct: 350 PLD--------ATGVAVFDIDMYGACLRALLADPAISLVAISQDCPSTLGKDQAATYRRL 401

Query: 435 WQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH 494
            Q       D      +     ++       +    L +A +  +  +  A      LI 
Sbjct: 402 VQAVAKVNADAA-KPIVFFNNISDTIHPAVLEP---LNEASVPSLCGMRNALRAIGHLID 457

Query: 495 PLSPAAQQHTPS----LLENVAVINIGLRSFALE----LQSASKPVVHYQWSPVAGGNKK 546
             + A  +HT        +    +  GL     E    L      V   Q +  A     
Sbjct: 458 HHAHAEVKHTSVGHLRDEQWAERLASGLPFTERESKAFLADHGIAVTREQLATNADDAAS 517

Query: 547 LARLL 551
            A+ L
Sbjct: 518 AAKRL 522


>UniRef50_A9ICC0 Putative acetyl-CoA synthetase n=1 Tax=Bordetella petrii DSM 12804
           RepID=A9ICC0_BORPD
          Length = 722

 Score =  174 bits (442), Expect = 6e-42,   Method: Composition-based stats.
 Identities = 67/529 (12%), Positives = 137/529 (25%), Gaps = 66/529 (12%)

Query: 66  VAIRSEAADAGIAQA-IMQQL-EEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALI 123
           VA+   +   G      ++ +      +L   +   +++  V  + S        +  ++
Sbjct: 29  VAVVGASDTPGSFGRHTLENIRVGYQGRLYAVNPKYRSVAGVPCYASLEDLPEVPDCVIV 88

Query: 124 SVAGEYAAELANQALDRNL-NVMMFSDNVT-------LEDEIQLKTRAREKGLLVMGPDC 175
           +V  +    L  QA    +  V++FS           +  + ++ T A E G+ ++GP+C
Sbjct: 89  AVPNDAVLPLVEQAAMCGVGGVIVFSSGFAEVGDIEKVRIQHRMATIAAETGMRIIGPNC 148

Query: 176 GTSMIAGTPLAFANVMP-------EGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
              + + +  A   +          G+IG+I  SG     +   +     G +H +  G 
Sbjct: 149 VGIVNSNSMAALTFMPKFNEMCWARGDIGLISQSGALGYCVLQGMERW-IGFSHYLSPGN 207

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEA-VRLKIVNAMKATGKPTVALFL 287
                    +     +  L  DE ++V+A + +   +    L+         KP +   +
Sbjct: 208 ------SCDVDVCDMINYLVDDESTKVIACMFEGVRDGARLLRAARRALEADKPLLIYKM 261

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTAR--------------RNAIAPVSSGFI 333
             +    R       +        A    R                   +      +  +
Sbjct: 262 ATSAISRRTALSHTGTMAGSEQAYAAAFERTGVVVVDDWEAMLETAVFFSKAGRPKASGV 321

Query: 334 CGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGD-DFYTVGRPHPMI 392
             + + G  A  AA                   +L A    I D G  D         + 
Sbjct: 322 GVIASSGGAAVMAADKAENLNVPLPAPAPGTADILKA---VIPDFGAVDNPCDLTAESLK 378

Query: 393 DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIA 452
              L  + I      P   V++   V    A             +          +  I 
Sbjct: 379 SLDLYGECIRAFANDPSYAVVV---VPMMSAHRPATVERARFISQLAETVNKPICIVWIN 435

Query: 453 TVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH--------PLSPAAQQHT 504
                             L      +  S+        A +            P+     
Sbjct: 436 EWLNGPG--SEIYDSSPRLS-----MFRSMRRCISAVRAWLTHYQRRDTLLRQPSRSPGR 488

Query: 505 P-----SLLENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLA 548
           P               +        L +   PV   + +         A
Sbjct: 489 PPAGRIGPAHAARSRTLSESESKRLLVAFGVPVTRERLADGVDAAVLAA 537


>UniRef50_B8X9X8 Pimeloyl-CoA synthetase n=1 Tax=Rhodococcus sp. TFB
           RepID=B8X9X8_9NOCA
          Length = 706

 Score =  174 bits (441), Expect = 8e-42,   Method: Composition-based stats.
 Identities = 75/458 (16%), Positives = 133/458 (29%), Gaps = 67/458 (14%)

Query: 66  VAIRSEAADAGIA-QAIMQQLEEALKQLAQGSGSSQA--LTQVRRWDSACQKL-PDANLA 121
           +A+   + D G      +  L+    +      + +   +  +    +  +    D +LA
Sbjct: 13  IAVVGASNDPGKLSGRPIAHLQRLGFKGQIVPVNPRRAMVQGLPAVATIEEITNDDVDLA 72

Query: 122 LISVAGEYAAELANQALDRNLNVMM-----FSD-NVTLEDEIQLKTRAREKGLLVMGPDC 175
           LI V     AE       R +   +     F++    +  + +L+    E G+ ++GP+C
Sbjct: 73  LIMVEAGRVAEAVRACGKRGIPAAIACASGFAETAGGVRLQDELRAAVEESGVRLLGPNC 132

Query: 176 GTSM--------IAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLG 227
              +           T L     +  G I  +  SG     + SQ    G G++H I  G
Sbjct: 133 LGMIGLHDRAVPTFTTALDNITDLAVGPIAFVSQSGAFGSLIFSQAQQMGLGMSHFITTG 192

Query: 228 GRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRL-KIVNAMKATGKPTVALF 286
                     +S    L  L  D  ++VL    +  A+   L +      A  KP +A+ 
Sbjct: 193 NE------VDLSVPELLNALVDDPHAQVLLTYLEGVADGRELIEAARKADAADKPLIAVK 246

Query: 287 LGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTG------- 339
           +G + + A        +     A            R               TG       
Sbjct: 247 VGRSTSGAAAARSHTGAIAGSDAVFDGFADEFGVIRPDSMGEMLDLAVMFGTGRRAQGRR 306

Query: 340 ----------GTLAAEAAGLLAGHLGVEAD---DTHQHGMMLDADSHQIIDLGDDFYTVG 386
                     G LA + A  L        D      +  +     S   IDL     +  
Sbjct: 307 LTTITLSGGAGVLATDVAEELGLDPSPWPDVWQREMRAAIPPYGSSKNPIDLTATMLS-- 364

Query: 387 RPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQ 446
                 DP L    +  +   P   ++L+ +          A     A  +A     +  
Sbjct: 365 ------DPDLLAGALGVVERNPDTDLVLIIL--------GNADDSAPALVEAIRRFHEKT 410

Query: 447 PLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPE 484
            +    + TG           +  L  AGI        
Sbjct: 411 HVPLAVSWTGGNGW------ALDELNGAGIPTYIDPSR 442


>UniRef50_C5D0J6 CoA-binding domain protein n=1 Tax=Variovorax paradoxus S110
           RepID=C5D0J6_VARPS
          Length = 710

 Score =  174 bits (440), Expect = 9e-42,   Method: Composition-based stats.
 Identities = 88/518 (16%), Positives = 160/518 (30%), Gaps = 50/518 (9%)

Query: 66  VAIRSEAADAGIAQAIMQQLE---EALKQLAQGSGSSQALTQVRRWDSACQKLPDANLAL 122
           +AI   + D         Q          +   +     +  ++ + S  +      LA+
Sbjct: 19  IAIFGASDDVTKIGGRPLQFLQKYGYGGGIYPINRKGGLVQSLQAYASVAELPEVPELAV 78

Query: 123 ISVAGEYAAELANQALDRNLNVMMF-SDNVTL------EDEIQLKTRAREKGLLVMGPDC 175
           I+V      +       R +   +  S   +         + ++   AR  G+ ++GP+C
Sbjct: 79  IAVPPAGVLDAVQDCAQRGVKAAVILSAGFSEMGEEGSRLQARIGEVARASGMRIVGPNC 138

Query: 176 GTSM------IAGTPLAFANVMPE-GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
             ++      IA   +A  +  P  G++G++  SG             G G++  +  G 
Sbjct: 139 LGAIGVPDKSIATFSVALESSFPAAGSVGIVSQSGNLGSFTLRMAGERGLGVSRMLTTGN 198

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLK-IVNAMKATGKPTVALFL 287
                    +    A+  L+AD  + V+    +   +  +L   +   +  GKP V L +
Sbjct: 199 E------CDVDIADAIASLAADPGTSVILCCMETCRDGAKLMQAMAMAREAGKPLVVLKV 252

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAA 347
           G + A +        +     A    +L +  A R     +       L   G     A 
Sbjct: 253 GVSEAGSAAAASHTGALAGSDAVFDAVLRQGGALRVPSIELLLEVGHALSVAGP----AR 308

Query: 348 GLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVG----RPHPMIDPTLRNQLIAD 403
                 + V         ++ DA S Q + L               P   P+    + A 
Sbjct: 309 VPGGHRVAVLTASGGFGVLLADAASAQGLALPKLAAQTQARILAAVPFAAPSNPVDMTAQ 368

Query: 404 LGAKPQVRVLLLDVV---------IGFGATADPAASLVSAWQKACAARLDNQPLYAIATV 454
           + ++P+V   +LD +         I   A A     L   + +A A    + P   I   
Sbjct: 369 VSSRPEVLAQMLDAMARDDSCNALILQSANAFHVPRLRDVFLEALAQVRKDHPARLI--- 425

Query: 455 TGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIH---PLSPAAQQHTPSLLENV 511
               R P+      A L   G  VV  +  A    AAL+      +        + +   
Sbjct: 426 LLCARAPEDV---RARLNAMGFPVVEGIDAACATLAALLRFGARDAARIAAPAIARVPLA 482

Query: 512 AVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLAR 549
           A       S    L  A  PV     +         AR
Sbjct: 483 AEAFATEASAKAVLAEAGLPVPWEAVACSLDEALAAAR 520


>UniRef50_B9B8Y3 CoA binding domain protein n=1 Tax=Burkholderia multivorans CGD1
           RepID=B9B8Y3_9BURK
          Length = 721

 Score =  173 bits (439), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 70/542 (12%), Positives = 133/542 (24%), Gaps = 82/542 (15%)

Query: 66  VAIRSEAADAGIAQ-AIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALIS 124
           +A+   +   G      +  L     ++   +   +         S        +  ++ 
Sbjct: 22  IAVVGASETPGSFGQRTLANLAGFQGKVFGVNPKYRETVGFACVPSLADLPESPDCVVMC 81

Query: 125 VAGEYAAELANQALDRNLN-VMMFSDNVTL-------EDEIQLKTRAREKGLLVMGPDCG 176
           VA         +A+       ++++   +          + +L   AR   + + GP+C 
Sbjct: 82  VAQSLVEPTLEEAIAVGAGGAIVYASGYSETGRAERIAAQERLVEIARRGAIRIAGPNCV 141

Query: 177 TSMIAGTPLAFANVM--------PEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGG 228
                 T  A   +           G + V+  SG     +  Q    G GI+H +  G 
Sbjct: 142 GLANVRTGAAMNFMPDCGKMINGRSGRVAVVSQSGALGYTVL-QAMTRGVGISHYLAAGN 200

Query: 229 RDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNA-MKATGKPTVALFL 287
                    +     +  L+ D +   +  + +      R         A GKP V    
Sbjct: 201 ------SSDVDVADFIATLADDPEVGSIICLFEGVKSGARFLEAARLADAAGKPLVVYKA 254

Query: 288 GYTPAVARDENVWFASSLDEAARLACLLSRVTARRNA---------------IAPVSSGF 332
           G T A  +       + +   A     L  V A +                  AP     
Sbjct: 255 GNTAASGKAALSHTGTLVGSVAAYRAALEEVGAIQTDDLEAVLEMANFFARNDAPKKGRG 314

Query: 333 ICGLYTGGTLA------AEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVG 386
           +  + T G         AE  GL    L     +     +          DL  +     
Sbjct: 315 VGIMATSGGAGVINADKAEQHGLELPELAAATHEALASVVPDFGSIANPADLTAEVLKTS 374

Query: 387 RPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQ 446
                   +     +      P    +++ +V    A      S      +  A R    
Sbjct: 375 --------STFAHCLNAFVDDPGFSAVVVPLVF---AHEAATGSRAPVICEVAARRKGAI 423

Query: 447 PLYAIATVTGTERDPQCRSQQIATL-EDAGIAVVSSLPEATLLAAALIHPLSPAAQQH-- 503
               +                 A L  D  + +  S         A        A +H  
Sbjct: 424 AAVWMNEWLEGP--------GSAVLDADPNVVLFRSADRCFSTIRAWCDWHERRALRHDK 475

Query: 504 --TPSLLENVAVIN------------IGLRSFALELQSASKPVVHYQWSPVAGGNKKLAR 549
               S  +  A               +G +     L +    V     +       + A 
Sbjct: 476 WLRRSASDAPATARAILAAAKARGNVLGEQDSKRVLAAYGIRVPRETVAATPDEAAQAAS 535

Query: 550 LL 551
            +
Sbjct: 536 AM 537


>UniRef50_B5I859 Succinyl-CoA ligase [ADP-forming] subunit alpha n=3
           Tax=Actinomycetales RepID=B5I859_9ACTO
          Length = 309

 Score =  173 bits (437), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 44/261 (16%), Positives = 95/261 (36%), Gaps = 12/261 (4%)

Query: 80  AIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLP--DANLALISVAGEYAAELANQA 137
           A    +   +     G         V  + S    +    A++ ++ V   +A     +A
Sbjct: 30  AAGTNVVGGVNPRKAGQRVDFDDRAVPVFGSVADGIGATGADVTVVFVPPPFAGAAVVEA 89

Query: 138 LDRNLN-VMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAG---TPLAFANVMPE 193
           +D  +   ++ ++ + + D +   + A++KG  ++GP+C   +  G     +  A++   
Sbjct: 90  VDAGIALAVVITEGIPVHDSVAFTSYAKKKGTRIVGPNCPGLITPGQSNAGIIPADITRS 149

Query: 194 GNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKS 253
           G IG++  SGT   +L  ++     G +  +G+GG      V G + +  L     D  +
Sbjct: 150 GRIGLVSKSGTLTYQLMYEL--RDIGFSTCVGIGGDP----VVGTTHIDCLAAFQDDPDT 203

Query: 254 EVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLAC 313
           E++  + +   +A         +   KP V    G+T    R      A     A     
Sbjct: 204 ELIVLIGEIGGDAEERAAAYIREHVTKPVVGYIAGFTAPEGRTMGHAGAIVSGSAGTARA 263

Query: 314 LLSRVTARRNAIAPVSSGFIC 334
             + + A    +    +    
Sbjct: 264 KKAALEAVGVKVGNTPTETAR 284


>UniRef50_A8A9G7 CoA-binding domain protein n=1 Tax=Ignicoccus hospitalis KIN4/I
           RepID=A8A9G7_IGNH4
          Length = 455

 Score =  172 bits (436), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 65/472 (13%), Positives = 131/472 (27%), Gaps = 62/472 (13%)

Query: 66  VAIRSEAAD-AGIAQAIMQQL-EEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALI 123
           VA+             I+  +      +L   +   + +  V  + S  +   +  LA++
Sbjct: 10  VAVVGATPKVPKPGYVILSNMKRSYKGKLYAVNPKYKEVLGVPCYPSLREVPDEVELAVV 69

Query: 124 SVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVMGPDCGTS 178
           +V       + + A+++++  ++     FS+    E E ++K +A   G+ V+GP+C   
Sbjct: 70  AVPTSAVEAVVDDAIEKDVRALIIITSGFSEVGNEELENRIKEKALSHGIRVVGPNCLGI 129

Query: 179 MIAGTPLAF-------ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDL 231
               + L                 + ++  SG     L    A  G G+  A+ LG +  
Sbjct: 130 YYYPSGLDTFFFREAGTPRPRPSGLALVSQSGALAASLMDWAASRGCGVGAAVSLGNK-- 187

Query: 232 SREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGK---PTVALFLG 288
                 +     L  L   E         +   E      +  +               G
Sbjct: 188 ----VDVGESEVLNYLFG-EGFNHFLMYIEGLREGEGKAFLETVLKLRLGGARIGFYKGG 242

Query: 289 YTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAG 348
                A       AS   +      LL    A           F+  L     L  +   
Sbjct: 243 RKRESAAAVASHTASVAGDYKAYRDLLFEFGATPLYDFAEVKAFVSALQYSPELRGDKLL 302

Query: 349 LLAGHLGV---------------EADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMID 393
           ++    G+                 D   +  +      +  +D+G D           D
Sbjct: 303 IVTDAGGIGIMLTDLIEGYKMPRPVDGELERELPSYLRLNNPLDVGGDA----------D 352

Query: 394 PTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIAT 453
                + +  L   P+  ++++           PA SL           ++      +  
Sbjct: 353 DERYRKALERLA--PKYDLIIV-----AALMESPATSLY--LADIVKESMERTGKPHLLL 403

Query: 454 VTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTP 505
             G     +   ++   LE   I     + EA   A  L+            
Sbjct: 404 GFGGTMA-EALERRARELE---IPFAFGVDEAVAYARVLLRDKFARELAEAR 451


>UniRef50_A4WJJ0 CoA-binding domain protein n=3 Tax=Pyrobaculum RepID=A4WJJ0_PYRAR
          Length = 484

 Score =  172 bits (435), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 67/448 (14%), Positives = 140/448 (31%), Gaps = 44/448 (9%)

Query: 61  PNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQ----VRRWDSACQKLP 116
           PN + V   S  AD+   Q ++Q L+    ++   +   +        V+ ++SA     
Sbjct: 7   PNSVAVVGASPKADSIGGQILLQLLKSFKSRVYAVNPKYRRGEVGGVEVQFYESATNLPE 66

Query: 117 DANLALISVAGEYAAELANQALDRNLNVMM-----FSDNVTLEDEIQLKTRAREKGLLVM 171
              L +++   E    + + A        +     FS+    + E +L   A++ G+ V+
Sbjct: 67  APELVVVATPAEITPRVVDDAGRAGAKAAIVVSGGFSEIGRRDLENELVKTAQKHGMRVL 126

Query: 172 GPDCGTSMIAGTPLAF-------ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAI 224
           GP+C     A   L         A   P G I  +  SG  +       A  G G+  A+
Sbjct: 127 GPNCIGVYNAFNGLDTMFLPVEKAARPPPGPIAFLSQSGAVMTAALDWAAGEGIGVGIAV 186

Query: 225 GLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPA-EAVRLKIVNAMKATGKPTV 283
             G R        ++    +E L+  ++  V+A   +    +    + +   K + KP V
Sbjct: 187 NFGNR------ADVTEADFIEFLANSKEISVIALYLEGFRWKGDAARFLKVAKRSSKPVV 240

Query: 284 ALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLA 343
               G     AR      A+          L  +                  L   G   
Sbjct: 241 VYKAGRGSDSARAAASHTAAMAGAYEMYHALFRQAGVIEADDLVELFDMAKALAVYGPRR 300

Query: 344 AEAAGLLAGHLG-------VEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTL 396
            ++  +++   G              +   + +    ++        TV  P  +     
Sbjct: 301 VDSVLVVSSSGGMGVQIVDAVNSVGLRVPELPEEGREELRKYLLPIATVSNPVDLTGGGN 360

Query: 397 RNQ--LIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATV 454
                   ++G +     ++  ++   G   D A  ++   +K             I   
Sbjct: 361 NAHFGKALEIGLRYTDAAVVAALIHPPGYNEDVAKEIIDVLEKHK--------KPIIVVS 412

Query: 455 TGTERDPQCRSQQIATLEDAGIAVVSSL 482
            G+    +   + +     + + VV++ 
Sbjct: 413 FGSSPQTKALEEALR----SRVVVVNTP 436


>UniRef50_A8KXI0 CoA-binding domain protein n=3 Tax=Frankia RepID=A8KXI0_FRASN
          Length = 977

 Score =  171 bits (434), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 67/446 (15%), Positives = 138/446 (30%), Gaps = 55/446 (12%)

Query: 65  CVAIRSEAADAGIA-QAIMQQLEEALKQLAQGSGSSQA--LTQVRRWDSACQKLPDANLA 121
            VA+   +   G A   + ++L  +         +  A  +  V  +    +     +LA
Sbjct: 287 AVAVVGASRQPGSAGHEVFRRLLASDFHGPVYPVNPAARQVASVYAYPDVREIPDAVDLA 346

Query: 122 LISVAGEYAAELANQALDRNLN-VMMFSDNVTLE------DEIQLKTRAREKGLLVMGPD 174
           +I+V     A+      ++++  +++ S               ++   ARE G+ ++GP+
Sbjct: 347 VIAVPAPAVADAVRACAEKDIRGLIVVSAGFAEAGPDGRARLAEVTRLARESGMRLIGPN 406

Query: 175 CGTSMIAGTPLAF-----ANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGR 229
               +     +       A   P G +G    SG       ++ +    G++  +  G R
Sbjct: 407 AMGVINTDPAVRLHATFAAGDPPVGRVGAFTQSGALAGTFLTEASRRAIGLSTFVSTGDR 466

Query: 230 DLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGY 289
                   +SA   L+   +D  ++V+    +      +   +       KP +AL  G 
Sbjct: 467 ------SDVSANDVLQYWQSDPHTDVIMLHLQGFGNPRKFARIARRVGRRKPVIALKSGR 520

Query: 290 TP------AVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLA 343
           +       A+     V    +L +   LA LL+           V             LA
Sbjct: 521 SAADPALDALFTSAGVIRVDTLSQLFDLAALLASQPLPAGRRVGVVGTS----SALAALA 576

Query: 344 AEAAGLLAGHLGVEADDTHQHGMMLDA--DSHQIIDLGDDFYTVGRPHPMIDPTLRNQLI 401
            +A       +   +  T +         +    +DLG           M  P    + +
Sbjct: 577 TDACRTAGLEVPPFSTATAEALSDTLGRPEPANPVDLGA----------MAAPERFERAL 626

Query: 402 ADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDP 461
             + A   V  +L  +              V    +A  A   +  +  +A+  G +  P
Sbjct: 627 RAVAASADVDAVLALITPHPA---------VEELARAVRAVAGSGRVPVVASYLGYDGMP 677

Query: 462 QCRS---QQIATLEDAGIAVVSSLPE 484
              +     I T     +   +S   
Sbjct: 678 SALAAPGDGIVTPAPGSVPSFASPES 703


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.308    0.127    0.311 

Lambda     K      H
   0.267   0.0390    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,671,745,075
Number of Sequences: 3077464
Number of extensions: 98336031
Number of successful extensions: 441495
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 542
Number of HSP's successfully gapped in prelim test: 1172
Number of HSP's that attempted gapping in prelim test: 435533
Number of HSP's gapped (non-prelim): 3685
length of query: 555
length of database: 1,040,396,356
effective HSP length: 134
effective length of query: 421
effective length of database: 628,016,180
effective search space: 264394811780
effective search space used: 264394811780
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 95 (41.3 bits)
