Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	V	A	P	I	P	A	K	R	G	R	K	P	A	V	A	T	A	P	A	T	G	Q	V	Q	S	L	T	R	G	L	K	L	L	E	W	I	A	E	S	N	G	S	V	A	L	T	E	L	A	Q	Q	A	G	L	P	N	S	T	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		H	R	L	L	T	T	M	Q	Q	Q	G	F	V	R	Q	V	G	E	L	G	H	W	A	I	G	A	H	A	F	M	V	G	S	S	F	L	Q	S	R	N	L	L	A	I	V	H	P	I	L	R	N	L	M	E	E	S	G	E	T	V
Secondary structure
SS confidence
Disorder																			?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		N	M	A	V	L	D	Q	S	D	H	E	A	I	I	I	D	Q	V	Q	C	T	H	L	M	R	M	S	A	P	I	G	G	K	L	P	M	H	A	S	G	A	G	K	A	F	L	A	Q	L	S	E	E	Q	V	T	K	L	L	H	R
Secondary structure
SS confidence
Disorder																														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		K	G	L	H	A	Y	T	H	A	T	L	V	S	P	V	H	L	K	E	D	L	A	Q	T	R	K	R	G	Y	S	F	D	D	E	E	H	A	L	G	L	R	C	L	A	A	C	I	F	D	E	H	R	E	P	F	A	A	I	S	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.
Sequence		S	G	P	I	S	R	I	T	D	D	R	V	T	E	F	G	A	M	V	I	K	A	A	K	E	V	T	L	A	Y	G	G	M	R
Secondary structure
SS confidence
Disorder																															?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1mkm chain A Region: 24 - 272 Aligned: 246 Modelled: 249 Confidence: 100.0% Identity: 28% PDB header:transcription Chain: A: PDB Molecule:iclr transcriptional regulator; PDBTitle: crystal structure of the thermotoga maritima iclr Phyre2 PDB 2g7u chain B Region: 21 - 272 Aligned: 248 Modelled: 247 Confidence: 100.0% Identity: 24% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:transcriptional regulator; PDBTitle: 2.3 a structure of putative catechol degradative operon regulator from2 rhodococcus sp. rha1 Phyre2 PDB 3r4k chain D Region: 24 - 274 Aligned: 246 Modelled: 250 Confidence: 100.0% Identity: 23% PDB header:dna binding protein Chain: D: PDB Molecule:transcriptional regulator, iclr family; PDBTitle: crystal structure of a putative iclr transcriptional regulator2 (tm1040_3717) from silicibacter sp. tm1040 at 2.46 a resolution Phyre2 PDB 3mq0 chain A Region: 18 - 272 Aligned: 243 Modelled: 255 Confidence: 100.0% Identity: 26% PDB header:transcription repressor Chain: A: PDB Molecule:transcriptional repressor of the blcabc operon; PDBTitle: crystal structure of agobacterium tumefaciens repressor blcr Phyre2 PDB 2ia2 chain D Region: 24 - 272 Aligned: 241 Modelled: 249 Confidence: 100.0% Identity: 25% PDB header:transcription Chain: D: PDB Molecule:putative transcriptional regulator; PDBTitle: the crystal structure of a putative transcriptional regulator rha061952 from rhodococcus sp. rha1 Phyre2 PDB 2o0y chain B Region: 22 - 273 Aligned: 241 Modelled: 252 Confidence: 100.0% Identity: 27% PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator; PDBTitle: crystal structure of putative transcriptional regulator rha1_ro069532 (iclr-family) from rhodococcus sp. Phyre2 PDB 2xro chain E Region: 25 - 271 Aligned: 238 Modelled: 245 Confidence: 100.0% Identity: 26% PDB header:dna-binding protein/dna Chain: E: PDB Molecule:hth-type transcriptional regulator ttgv; PDBTitle: crystal structure of ttgv in complex with its dna operator Phyre2 PDB 2o9a chain A domain 1 Region: 96 - 274 Aligned: 179 Modelled: 179 Confidence: 100.0% Identity: 99% Fold: Profilin-like Superfamily: GAF domain-like Family: IclR ligand-binding domain-like Phyre2 PDB 1tf1 chain A Region: 91 - 272 Aligned: 180 Modelled: 182 Confidence: 100.0% Identity: 43% Fold: Profilin-like Superfamily: GAF domain-like Family: IclR ligand-binding domain-like Phyre2 PDB 1mkm chain A domain 2 Region: 100 - 272 Aligned: 171 Modelled: 173 Confidence: 100.0% Identity: 32% Fold: Profilin-like Superfamily: GAF domain-like Family: IclR ligand-binding domain-like Phyre2 PDB 3obf chain A Region: 97 - 272 Aligned: 173 Modelled: 176 Confidence: 100.0% Identity: 24% PDB header:transcription regulator Chain: A: PDB Molecule:putative transcriptional regulator, iclr family; PDBTitle: crystal structure of putative transcriptional regulator, iclr family;2 targeted domain 129...302 Phyre2 PDB 1ysp chain A Region: 99 - 272 Aligned: 164 Modelled: 174 Confidence: 100.0% Identity: 30% PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator kdgr; PDBTitle: crystal structure of the c-terminal domain of e. coli transcriptional2 regulator kdgr. Phyre2 PDB 1ysq chain A Region: 98 - 272 Aligned: 173 Modelled: 175 Confidence: 100.0% Identity: 28% PDB header:gene regulation Chain: A: PDB Molecule:hth-type transcriptional regulator yiaj; PDBTitle: the crystal structure of transcriptional regulator yaij Phyre2 PDB 3d3o chain A Region: 103 - 271 Aligned: 166 Modelled: 169 Confidence: 100.0% Identity: 14% PDB header:transcription regulator Chain: A: PDB Molecule:putative transcriptional regulator, icir family; PDBTitle: crystal structure of the effector domain of the putative2 transcriptional regulator iclr from acinetobacter sp. adp1 Phyre2 PDB 3bjn chain A Region: 94 - 266 Aligned: 162 Modelled: 173 Confidence: 100.0% Identity: 21% PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, putative; PDBTitle: crystal structure of c-terminal domain of putative transcriptional2 regulator from vibrio cholerae, targeted domain 79-240 Phyre2 PDB 1mkm chain A domain 1 Region: 24 - 99 Aligned: 75 Modelled: 76 Confidence: 99.7% Identity: 20% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Transcriptional regulator IclR, N-terminal domain Phyre2 PDB 2quf chain B Region: 31 - 216 Aligned: 182 Modelled: 186 Confidence: 98.8% Identity: 13% PDB header:transcription Chain: B: PDB Molecule:transcription factor pf0095; PDBTitle: crystal structure of transcription factor axxa-pf0095 from pyrococcus2 furiosus Phyre2 PDB 2it0 chain A Region: 25 - 105 Aligned: 80 Modelled: 81 Confidence: 98.2% Identity: 11% PDB header:transcription/dna Chain: A: PDB Molecule:iron-dependent repressor ider; PDBTitle: crystal structure of a two-domain ider-dna complex crystal2 form ii Phyre2 PDB 2h09 chain A Region: 25 - 109 Aligned: 84 Modelled: 85 Confidence: 98.1% Identity: 11% PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator mntr; PDBTitle: crystal structure of diphtheria toxin repressor like protein2 from e. coli Phyre2 PDB 1f5t chain A Region: 25 - 105 Aligned: 80 Modelled: 81 Confidence: 98.1% Identity: 10% PDB header:transcription/dna Chain: A: PDB Molecule:diphtheria toxin repressor; PDBTitle: diphtheria tox repressor (c102d mutant) complexed with2 nickel and dtxr consensus binding sequence Phyre2 1 c1mkmA_ 2 c2g7uB_ 3 c3r4kD_ 4 c3mq0A_ 5 c2ia2D_ 6 c2o0yB_ 7 c2xroE_ 8 d2o9aa1 9 d1tf1a_ 10 d1mkma2 11 c3obfA_ 12 c1yspA_ 13 c1ysqA_ 14 c3d3oA_ 15 c3bjnA_ 16 d1mkma1 17 c2qufB_ 18 c2it0A_ 19 c2h09A_ 20 c1f5tA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499