Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	I	T	I	I	L	V	A	P	A	R	A	E	N	I	G	A	A	A	R	A	M	K	T	M	G	F	S	D	L	R	I	V	D	S	Q	A	H	L	E	P	A	T	R	W	V	A	H	G	S	G	D	I	I	D	N	I	K	V
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		F	P	T	L	A	E	S	L	H	D	V	D	F	T	V	A	T	T	A	R	S	R	A	K	Y	H	Y	Y	A	T	P	V	E	L	V	P	L	L	E	E	K	S	S	W	M	S	H	A	A	L	V	F	G	R	E	D	S	G	L	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		N	E	E	L	A	L	A	D	V	L	T	G	V	P	M	V	A	D	Y	P	S	L	N	L	G	Q	A	V	M	V	Y	C	Y	Q	L	A	T	L	I	Q	Q	P	A	K	S	D	A	T	A	D	Q	H	Q	L	Q	A	L	R	E	R
Secondary structure
SS confidence
Disorder																				?																			?		?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.
Sequence		A	M	T	L	L	T	T	L	A	V	A	D	D	I	K	L	V	D	W	L	Q	Q	R	L	G	L	L	E	Q	R	D	T	A	M	L	H	R	L	L	H	D	I	E	K	N	I	T	K
Secondary structure
SS confidence
Disorder																																															?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3ilk chain B Region: 2 - 227 Aligned: 222 Modelled: 216 Confidence: 100.0% Identity: 28% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized trna/rrna methyltransferase hi0380; PDBTitle: the structure of a probable methylase family protein from haemophilus2 influenzae rd kw20 Phyre2 PDB 3ic6 chain A Region: 2 - 183 Aligned: 180 Modelled: 179 Confidence: 100.0% Identity: 35% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative methylase family protein; PDBTitle: crystal structure of putative methylase family protein from neisseria2 gonorrhoeae Phyre2 PDB 3onp chain A Region: 1 - 158 Aligned: 158 Modelled: 153 Confidence: 100.0% Identity: 37% PDB header:transferase Chain: A: PDB Molecule:trna/rrna methyltransferase (spou); PDBTitle: crystal structure of trna/rrna methyltransferase spou from rhodobacter2 sphaeroides Phyre2 PDB 1zjr chain A Region: 2 - 185 Aligned: 174 Modelled: 183 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:trna (guanosine-2'-o-)-methyltransferase; PDBTitle: crystal structure of a. aeolicus trmh/spou trna modifying enzyme Phyre2 PDB 1v2x chain A Region: 2 - 180 Aligned: 168 Modelled: 168 Confidence: 100.0% Identity: 23% Fold: alpha/beta knot Superfamily: alpha/beta knot Family: SpoU-like RNA 2'-O ribose methyltransferase Phyre2 PDB 3kty chain A Region: 1 - 159 Aligned: 155 Modelled: 153 Confidence: 100.0% Identity: 29% PDB header:transferase Chain: A: PDB Molecule:probable methyltransferase; PDBTitle: crystal structure of probable methyltransferase from bordetella2 pertussis tohama i Phyre2 PDB 2ha8 chain A Region: 2 - 158 Aligned: 148 Modelled: 148 Confidence: 100.0% Identity: 16% PDB header:rna binding protein Chain: A: PDB Molecule:tar (hiv-1) rna loop binding protein; PDBTitle: methyltransferase domain of human tar (hiv-1) rna binding2 protein 1 Phyre2 PDB 1gz0 chain A domain 1 Region: 2 - 158 Aligned: 146 Modelled: 157 Confidence: 100.0% Identity: 18% Fold: alpha/beta knot Superfamily: alpha/beta knot Family: SpoU-like RNA 2'-O ribose methyltransferase Phyre2 PDB 1gz0 chain G Region: 2 - 158 Aligned: 146 Modelled: 139 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: G: PDB Molecule:hypothetical trna/rrna methyltransferase yjfh; PDBTitle: 23s ribosomal rna g2251 2'o-methyltransferase rlmb Phyre2 PDB 2i6d chain A Region: 2 - 158 Aligned: 148 Modelled: 147 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:rna methyltransferase, trmh family; PDBTitle: the structure of a putative rna methyltransferase of the trmh family2 from porphyromonas gingivalis. Phyre2 PDB 1ipa chain A Region: 1 - 158 Aligned: 146 Modelled: 146 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:rna 2'-o-ribose methyltransferase; PDBTitle: crystal structure of rna 2'-o ribose methyltransferase Phyre2 PDB 1x7p chain B Region: 3 - 158 Aligned: 148 Modelled: 148 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: B: PDB Molecule:rrna methyltransferase; PDBTitle: crystal structure of the spou methyltransferase avirb from2 streptomyces viridochromogenes in complex with the cofactor adomet Phyre2 PDB 1mxi chain A Region: 3 - 164 Aligned: 150 Modelled: 150 Confidence: 100.0% Identity: 19% Fold: alpha/beta knot Superfamily: alpha/beta knot Family: SpoU-like RNA 2'-O ribose methyltransferase Phyre2 PDB 1ipa chain A domain 1 Region: 3 - 158 Aligned: 144 Modelled: 144 Confidence: 100.0% Identity: 17% Fold: alpha/beta knot Superfamily: alpha/beta knot Family: SpoU-like RNA 2'-O ribose methyltransferase Phyre2 PDB 3gyq chain B Region: 3 - 158 Aligned: 147 Modelled: 147 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: B: PDB Molecule:rrna (adenosine-2'-o-)-methyltransferase; PDBTitle: structure of the thiostrepton-resistance methyltransferase2 s-adenosyl-l-methionine complex Phyre2 PDB 3dcm chain X Region: 2 - 155 Aligned: 154 Modelled: 154 Confidence: 100.0% Identity: 14% PDB header:transferase Chain: X: PDB Molecule:uncharacterized protein tm_1570; PDBTitle: crystal structure of the thermotoga maritima spout family2 rna-methyltransferase protein tm1570 in complex with s-3 adenosyl-l-methionine Phyre2 PDB 3e5y chain B Region: 3 - 164 Aligned: 137 Modelled: 137 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:trmh family rna methyltransferase; PDBTitle: crystal structure of trmh family rna methyltransferase from2 burkholderia pseudomallei Phyre2 PDB 3l8u chain A Region: 2 - 167 Aligned: 148 Modelled: 148 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:putative rrna methylase; PDBTitle: crystal structure of smu.1707c, a putative rrna methyltransferase from2 streptococcus mutans ua159 Phyre2 PDB 1vhk chain A Region: 2 - 155 Aligned: 142 Modelled: 154 Confidence: 97.0% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein yqeu; PDBTitle: crystal structure of an hypothetical protein Phyre2 PDB 1vhk chain A domain 2 Region: 1 - 161 Aligned: 149 Modelled: 161 Confidence: 96.8% Identity: 13% Fold: alpha/beta knot Superfamily: alpha/beta knot Family: YggJ C-terminal domain-like Phyre2 1 c3ilkB_ 2 c3ic6A_ 3 c3onpA_ 4 c1zjrA_ 5 d1v2xa_ 6 c3ktyA_ 7 c2ha8A_ 8 d1gz0a1 9 c1gz0G_ 10 c2i6dA_ 11 c1ipaA_ 12 c1x7pB_ 13 d1mxia_ 14 d1ipaa1 15 c3gyqB_ 16 c3dcmX_ 17 c3e5yB_ 18 c3l8uA_ 19 c1vhkA_ 20 d1vhka2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3ilkB_ 100.0 28 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized trna/rrna methyltransferase hi0380; PDBTitle: the structure of a probable methylase family protein from haemophilus2 influenzae rd kw20 2 c3ic6A_ 100.0 35 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative methylase family protein; PDBTitle: crystal structure of putative methylase family protein from neisseria2 gonorrhoeae 3 c3onpA_ 100.0 37 PDB header:transferase Chain: A: PDB Molecule:trna/rrna methyltransferase (spou); PDBTitle: crystal structure of trna/rrna methyltransferase spou from rhodobacter2 sphaeroides 4 c1zjrA_ 100.0 17 PDB header:transferase Chain: A: PDB Molecule:trna (guanosine-2'-o-)-methyltransferase; PDBTitle: crystal structure of a. aeolicus trmh/spou trna modifying enzyme 5 d1v2xa_ 100.0 23 Fold:alpha/beta knot Superfamily:alpha/beta knot Family:SpoU-like RNA 2'-O ribose methyltransferase 6 c3ktyA_ 100.0 29 PDB header:transferase Chain: A: PDB Molecule:probable methyltransferase; PDBTitle: crystal structure of probable methyltransferase from bordetella2 pertussis tohama i 7 c2ha8A_ 100.0 16 PDB header:rna binding protein Chain: A: PDB Molecule:tar (hiv-1) rna loop binding protein; PDBTitle: methyltransferase domain of human tar (hiv-1) rna binding2 protein 1 8 d1gz0a1 100.0 18 Fold:alpha/beta knot Superfamily:alpha/beta knot Family:SpoU-like RNA 2'-O ribose methyltransferase 9 c1gz0G_ 100.0 18 PDB header:transferase Chain: G: PDB Molecule:hypothetical trna/rrna methyltransferase yjfh; PDBTitle: 23s ribosomal rna g2251 2'o-methyltransferase rlmb 10 c2i6dA_ 100.0 19 PDB header:transferase Chain: A: PDB Molecule:rna methyltransferase, trmh family; PDBTitle: the structure of a putative rna methyltransferase of the trmh family2 from porphyromonas gingivalis. 11 c1ipaA_ 100.0 16 PDB header:transferase Chain: A: PDB Molecule:rna 2'-o-ribose methyltransferase; PDBTitle: crystal structure of rna 2'-o ribose methyltransferase 12 c1x7pB_ 100.0 21 PDB header:transferase Chain: B: PDB Molecule:rrna methyltransferase; PDBTitle: crystal structure of the spou methyltransferase avirb from2 streptomyces viridochromogenes in complex with the cofactor adomet 13 d1mxia_ 100.0 19 Fold:alpha/beta knot Superfamily:alpha/beta knot Family:SpoU-like RNA 2'-O ribose methyltransferase 14 d1ipaa1 100.0 17 Fold:alpha/beta knot Superfamily:alpha/beta knot Family:SpoU-like RNA 2'-O ribose methyltransferase 15 c3gyqB_ 100.0 19 PDB header:transferase Chain: B: PDB Molecule:rrna (adenosine-2'-o-)-methyltransferase; PDBTitle: structure of the thiostrepton-resistance methyltransferase2 s-adenosyl-l-methionine complex 16 c3dcmX_ 100.0 14 PDB header:transferase Chain: X: PDB Molecule:uncharacterized protein tm_1570; PDBTitle: crystal structure of the thermotoga maritima spout family2 rna-methyltransferase protein tm1570 in complex with s-3 adenosyl-l-methionine 17 c3e5yB_ 100.0 18 PDB header:transferase Chain: B: PDB Molecule:trmh family rna methyltransferase; PDBTitle: crystal structure of trmh family rna methyltransferase from2 burkholderia pseudomallei 18 c3l8uA_ 100.0 20 PDB header:transferase Chain: A: PDB Molecule:putative rrna methylase; PDBTitle: crystal structure of smu.1707c, a putative rrna methyltransferase from2 streptococcus mutans ua159 19 c1vhkA_ 97.0 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein yqeu; PDBTitle: crystal structure of an hypothetical protein 20 d1vhka2 96.8 13 Fold:alpha/beta knot Superfamily:alpha/beta knot Family:YggJ C-terminal domain-like 21 d1nxza2 not modelled 96.4 15 Fold:alpha/beta knot Superfamily:alpha/beta knot Family:YggJ C-terminal domain-like 22 c2egwB_ not modelled 95.7 13 PDB header:rna methyltransferase Chain: B: PDB Molecule:upf0088 protein aq_165; PDBTitle: crystal structure of rrna methyltransferase with sah ligand 23 c3kw2A_ not modelled 95.7 17 PDB header:transferase Chain: A: PDB Molecule:probable r-rna methyltransferase; PDBTitle: crystal structure of probable rrna-methyltransferase from2 porphyromonas gingivalis 24 c1vhyB_ not modelled 95.5 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein hi0303; PDBTitle: crystal structure of haemophilus influenzae protein hi0303, pfam2 duf558 25 d1v6za2 not modelled 95.2 17 Fold:alpha/beta knot Superfamily:alpha/beta knot Family:YggJ C-terminal domain-like 26 c2yy8B_ not modelled 94.7 17 PDB header:transferase Chain: B: PDB Molecule:upf0106 protein ph0461; PDBTitle: crystal structure of archaeal trna-methylase for position2 56 (atrm56) from pyrococcus horikoshii, complexed with s-3 adenosyl-l-methionine 27 c2cx8B_ not modelled 94.6 18 PDB header:transferase Chain: B: PDB Molecule:methyl transferase; PDBTitle: crystal structure of methyltransferase with ligand(sah) 28 d2o3aa1 not modelled 93.6 17 Fold:alpha/beta knot Superfamily:alpha/beta knot Family:AF0751-like 29 d1duvg2 not modelled 85.0 20 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 30 d1otha2 not modelled 84.4 14 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 31 d1pvva2 not modelled 84.1 11 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 32 c3d6nB_ not modelled 82.6 9 PDB header:hydrolase/transferase Chain: B: PDB Molecule:aspartate carbamoyltransferase; PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase 33 d1js1x2 not modelled 81.9 16 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 34 c1a1sA_ not modelled 81.2 11 PDB header:transcarbamylase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: ornithine carbamoyltransferase from pyrococcus furiosus 35 d1dxha2 not modelled 80.3 13 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 36 d1ml4a2 not modelled 80.2 14 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 37 d1pg5a2 not modelled 78.2 12 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 38 c2otcA_ not modelled 77.5 21 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: ornithine transcarbamoylase complexed with n-2 (phosphonacetyl)-l-ornithine 39 c2w37A_ not modelled 76.2 12 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase, catabolic; PDBTitle: crystal structure of the hexameric catabolic ornithine2 transcarbamylase from lactobacillus hilgardii 40 c1z85B_ not modelled 74.4 13 PDB header:transferase Chain: B: PDB Molecule:hypothetical protein tm1380; PDBTitle: crystal structure of a predicted rna methyltransferase (tm1380) from2 thermotoga maritima msb8 at 2.12 a resolution 41 d1ekxa2 not modelled 74.0 15 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 42 d1vlva2 not modelled 72.3 9 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 43 c1pg5A_ not modelled 72.1 12 PDB header:transferase Chain: A: PDB Molecule:aspartate carbamoyltransferase; PDBTitle: crystal structure of the unligated (t-state) aspartate2 transcarbamoylase from the extremely thermophilic archaeon sulfolobus3 acidocaldarius 44 c2p2gD_ not modelled 69.8 18 PDB header:transferase Chain: D: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form 45 c1vlvA_ not modelled 66.8 11 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase (tm1097) from2 thermotoga maritima at 2.25 a resolution 46 c1k3rA_ not modelled 64.0 27 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved protein mt0001; PDBTitle: crystal structure of the methyltransferase with a knot from2 methanobacterium thermoautotrophicum 47 c3updA_ not modelled 63.7 20 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: 2.9 angstrom crystal structure of ornithine carbamoyltransferase2 (argf) from vibrio vulnificus 48 c1a5zA_ not modelled 62.8 15 PDB header:oxidoreductase Chain: A: PDB Molecule:l-lactate dehydrogenase; PDBTitle: lactate dehydrogenase from thermotoga maritima (tmldh) 49 d1up7a1 not modelled 62.2 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 50 c2omeA_ not modelled 61.0 25 PDB header:oxidoreductase Chain: A: PDB Molecule:c-terminal-binding protein 2; PDBTitle: crystal structure of human ctbp2 dehydrogenase complexed with nad(h) 51 c1fvoB_ not modelled 60.4 14 PDB header:transferase Chain: B: PDB Molecule:ornithine transcarbamylase; PDBTitle: crystal structure of human ornithine transcarbamylase complexed with2 carbamoyl phosphate 52 c1ortD_ not modelled 60.3 16 PDB header:transferase Chain: D: PDB Molecule:ornithine transcarbamoylase; PDBTitle: ornithine transcarbamoylase from pseudomonas aeruginosa 53 d1ygya1 not modelled 59.3 26 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Formate/glycerate dehydrogenases, NAD-domain 54 c1ml4A_ not modelled 59.0 14 PDB header:transferase Chain: A: PDB Molecule:aspartate transcarbamoylase; PDBTitle: the pala-liganded aspartate transcarbamoylase catalytic subunit from2 pyrococcus abyssi 55 c2rgwD_ not modelled 59.0 15 PDB header:transferase Chain: D: PDB Molecule:aspartate carbamoyltransferase; PDBTitle: catalytic subunit of m. jannaschii aspartate2 transcarbamoylase 56 c3n7uD_ not modelled 58.9 23 PDB header:oxidoreductase Chain: D: PDB Molecule:formate dehydrogenase; PDBTitle: nad-dependent formate dehydrogenase from higher-plant arabidopsis2 thaliana in complex with nad and azide 57 c2v6bB_ not modelled 58.8 19 PDB header:oxidoreductase Chain: B: PDB Molecule:l-lactate dehydrogenase; PDBTitle: crystal structure of lactate dehydrogenase from deinococcus2 radiodurans (apo form) 58 c2g76A_ not modelled 58.5 22 PDB header:oxidoreductase Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase; PDBTitle: crystal structure of human 3-phosphoglycerate dehydrogenase 59 d1k3ra2 not modelled 56.8 27 Fold:alpha/beta knot Superfamily:alpha/beta knot Family:Hypothetical protein MTH1 (MT0001), dimerisation domain 60 c3gg9C_ not modelled 56.6 16 PDB header:oxidoreductase Chain: C: PDB Molecule:d-3-phosphoglycerate dehydrogenase oxidoreductase protein; PDBTitle: crystal structure of putative d-3-phosphoglycerate dehydrogenase2 oxidoreductase from ralstonia solanacearum 61 c2nacA_ not modelled 56.0 19 PDB header:oxidoreductase(aldehyde(d),nad+(a)) Chain: A: PDB Molecule:nad-dependent formate dehydrogenase; PDBTitle: high resolution structures of holo and apo formate dehydrogenase 62 d1obba1 not modelled 55.4 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 63 c3grfA_ not modelled 55.3 15 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: x-ray structure of ornithine transcarbamoylase from giardia2 lamblia 64 c3evtA_ not modelled 53.8 22 PDB header:oxidoreductase Chain: A: PDB Molecule:phosphoglycerate dehydrogenase; PDBTitle: crystal structure of phosphoglycerate dehydrogenase from2 lactobacillus plantarum 65 d2naca1 not modelled 53.3 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Formate/glycerate dehydrogenases, NAD-domain 66 c3bazA_ not modelled 53.3 15 PDB header:oxidoreductase Chain: A: PDB Molecule:hydroxyphenylpyruvate reductase; PDBTitle: structure of hydroxyphenylpyruvate reductase from coleus blumei in2 complex with nadp+ 67 d1qp8a1 not modelled 53.1 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Formate/glycerate dehydrogenases, NAD-domain 68 d1sc6a1 not modelled 51.0 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Formate/glycerate dehydrogenases, NAD-domain 69 d1mx3a1 not modelled 51.0 24 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Formate/glycerate dehydrogenases, NAD-domain 70 c1js1Z_ not modelled 49.6 13 PDB header:transferase Chain: Z: PDB Molecule:transcarbamylase; PDBTitle: crystal structure of a new transcarbamylase from the2 anaerobic bacterium bacteroides fragilis at 2.0 a3 resolution 71 c1d4fD_ not modelled 48.6 17 PDB header:hydrolase Chain: D: PDB Molecule:s-adenosylhomocysteine hydrolase; PDBTitle: crystal structure of recombinant rat-liver d244e mutant s-2 adenosylhomocysteine hydrolase 72 c1j4aA_ not modelled 47.7 16 PDB header:oxidoreductase Chain: A: PDB Molecule:d-lactate dehydrogenase; PDBTitle: insights into domain closure, substrate specificity and2 catalysis of d-lactate dehydrogenase from lactobacillus3 bulgaricus 73 c1zq2A_ not modelled 45.3 17 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of n-acetyl-l-ornithine transcarbamylase2 complexed with cp 74 c3ijpA_ not modelled 45.1 9 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrodipicolinate reductase; PDBTitle: crystal structure of dihydrodipicolinate reductase from2 bartonella henselae at 2.0a resolution 75 d1gdha1 not modelled 44.2 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Formate/glycerate dehydrogenases, NAD-domain 76 c3gvpB_ not modelled 42.1 19 PDB header:hydrolase Chain: B: PDB Molecule:adenosylhomocysteinase 3; PDBTitle: human sahh-like domain of human adenosylhomocysteinase 3 77 c1qp8A_ not modelled 40.3 16 PDB header:oxidoreductase Chain: A: PDB Molecule:formate dehydrogenase; PDBTitle: crystal structure of a putative formate dehydrogenase from2 pyrobaculum aerophilum 78 c2pwzG_ not modelled 40.1 18 PDB header:oxidoreductase Chain: G: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of the apo form of e.coli malate dehydrogenase 79 c3gd5D_ not modelled 40.0 8 PDB header:transferase Chain: D: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from gloeobacter2 violaceus 80 c1gdhA_ not modelled 39.8 15 PDB header:oxidoreductase(choh (d)-nad(p)+ (a)) Chain: A: PDB Molecule:d-glycerate dehydrogenase; PDBTitle: crystal structure of a nad-dependent d-glycerate2 dehydrogenase at 2.4 angstroms resolution 81 d2at2a2 not modelled 39.7 8 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 82 c1wwkA_ not modelled 39.4 22 PDB header:oxidoreductase Chain: A: PDB Molecule:phosphoglycerate dehydrogenase; PDBTitle: crystal structure of phosphoglycerate dehydrogenase from pyrococcus2 horikoshii ot3 83 d1a5za1 not modelled 39.4 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 84 d1u8xx1 not modelled 38.9 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 85 d2cmda1 not modelled 38.6 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 86 d1gpja2 not modelled 38.4 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 87 d1j4aa1 not modelled 37.5 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Formate/glycerate dehydrogenases, NAD-domain 88 c3q98A_ not modelled 35.7 10 PDB header:transferase Chain: A: PDB Molecule:transcarbamylase; PDBTitle: structure of ygew encoded protein from e. coli 89 c2gcgB_ not modelled 35.2 24 PDB header:oxidoreductase Chain: B: PDB Molecule:glyoxylate reductase/hydroxypyruvate reductase; PDBTitle: ternary crystal structure of human glyoxylate2 reductase/hydroxypyruvate reductase 90 c3hg7A_ not modelled 34.4 24 PDB header:oxidoreductase Chain: A: PDB Molecule:d-isomer specific 2-hydroxyacid dehydrogenase family PDBTitle: crystal structure of d-isomer specific 2-hydroxyacid dehydrogenase2 family protein from aeromonas salmonicida subsp. salmonicida a449 91 d7reqb2 not modelled 31.4 15 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 92 c2j6iC_ not modelled 31.4 23 PDB header:oxidoreductase Chain: C: PDB Molecule:formate dehydrogenase; PDBTitle: candida boidinii formate dehydrogenase (fdh) c-terminal2 mutant 93 d1tuga1 not modelled 30.9 10 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 94 c2pi1C_ not modelled 30.9 20 PDB header:oxidoreductase Chain: C: PDB Molecule:d-lactate dehydrogenase; PDBTitle: crystal structure of d-lactate dehydrogenase from aquifex2 aeolicus complexed with nad and lactic acid 95 d1s6ya1 not modelled 30.3 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 96 c1mldA_ not modelled 29.8 20 PDB header:oxidoreductase(nad(a)-choh(d)) Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: refined structure of mitochondrial malate dehydrogenase2 from porcine heart and the consensus structure for3 dicarboxylic acid oxidoreductases 97 c2d0iC_ not modelled 29.0 22 PDB header:oxidoreductase Chain: C: PDB Molecule:dehydrogenase; PDBTitle: crystal structure ph0520 protein from pyrococcus horikoshii ot3 98 d1diha1 not modelled 28.8 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 99 c2dbqA_ not modelled 28.8 22 PDB header:oxidoreductase Chain: A: PDB Molecule:glyoxylate reductase; PDBTitle: crystal structure of glyoxylate reductase (ph0597) from pyrococcus2 horikoshii ot3, complexed with nadp (i41) 100 c2y0fD_ not modelled 28.0 24 PDB header:oxidoreductase Chain: D: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PDBTitle: structure of gcpe (ispg) from thermus thermophilus hb27 101 c3lxmC_ not modelled 27.9 19 PDB header:transferase Chain: C: PDB Molecule:aspartate carbamoyltransferase; PDBTitle: 2.00 angstrom resolution crystal structure of a catalytic2 subunit of an aspartate carbamoyltransferase (pyrb) from3 yersinia pestis co92 102 c3sdsA_ not modelled 27.9 18 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase, mitochondrial; PDBTitle: crystal structure of a mitochondrial ornithine carbamoyltransferase2 from coccidioides immitis 103 c3dhyC_ not modelled 27.9 22 PDB header:hydrolase Chain: C: PDB Molecule:adenosylhomocysteinase; PDBTitle: crystal structures of mycobacterium tuberculosis s-adenosyl-l-2 homocysteine hydrolase in ternary complex with substrate and3 inhibitors 104 c1ybaC_ not modelled 27.3 23 PDB header:oxidoreductase Chain: C: PDB Molecule:d-3-phosphoglycerate dehydrogenase; PDBTitle: the active form of phosphoglycerate dehydrogenase 105 c2w2kB_ not modelled 26.2 17 PDB header:oxidoreductase Chain: B: PDB Molecule:d-mandelate dehydrogenase; PDBTitle: crystal structure of the apo forms of rhodotorula graminis2 d-mandelate dehydrogenase at 1.8a. 106 c2cukC_ not modelled 25.7 24 PDB header:oxidoreductase Chain: C: PDB Molecule:glycerate dehydrogenase/glyoxylate reductase; PDBTitle: crystal structure of tt0316 protein from thermus thermophilus hb8 107 d2dlda1 not modelled 25.5 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Formate/glycerate dehydrogenases, NAD-domain 108 c1dxyA_ not modelled 25.2 17 PDB header:oxidoreductase Chain: A: PDB Molecule:d-2-hydroxyisocaproate dehydrogenase; PDBTitle: structure of d-2-hydroxyisocaproate dehydrogenase 109 c2eklA_ not modelled 24.5 24 PDB header:oxidoreductase Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase; PDBTitle: structure of st1218 protein from sulfolobus tokodaii 110 c8ldhA_ not modelled 24.5 18 PDB header:oxidoreductase(choh(d)-nad(a)) Chain: A: PDB Molecule:m4 apo-lactate dehydrogenase; PDBTitle: refined crystal structure of dogfish m4 apo-lactate2 dehydrogenase 111 c3ckyA_ not modelled 23.6 15 PDB header:oxidoreductase Chain: A: PDB Molecule:2-hydroxymethyl glutarate dehydrogenase; PDBTitle: structural and kinetic properties of a beta-hydroxyacid dehydrogenase2 involved in nicotinate fermentation 112 c1xdwA_ not modelled 23.2 23 PDB header:oxidoreductase Chain: A: PDB Molecule:nad+-dependent (r)-2-hydroxyglutarate PDBTitle: nad+-dependent (r)-2-hydroxyglutarate dehydrogenase from2 acidaminococcus fermentans 113 d1o94c_ not modelled 21.8 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 114 c3oirA_ not modelled 21.4 15 PDB header:transport protein Chain: A: PDB Molecule:sulfate transporter sulfate transporter family protein; PDBTitle: crystal structure of sulfate transporter family protein from wolinella2 succinogenes 115 c2v3jA_ not modelled 21.4 18 PDB header:ribosomal protein Chain: A: PDB Molecule:essential for mitotic growth 1; PDBTitle: the yeast ribosome synthesis factor emg1 alpha beta knot2 fold methyltransferase 116 c3kboB_ not modelled 20.9 22 PDB header:oxidoreductase Chain: B: PDB Molecule:glyoxylate/hydroxypyruvate reductase a; PDBTitle: 2.14 angstrom crystal structure of putative oxidoreductase (ycdw) from2 salmonella typhimurium in complex with nadp 117 c3n58D_ not modelled 20.8 17 PDB header:hydrolase Chain: D: PDB Molecule:adenosylhomocysteinase; PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from brucella2 melitensis in ternary complex with nad and adenosine, orthorhombic3 form

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0