Phyre 2 Results for P27247

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Email | l.a.kelley@imperial.ac.uk
Description | P27247
Date | Thu Jan 5 11:43:26 GMT 2012
Unique Job ID | 13addc5eb3f6a62d

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template d1u7na_
Top template information
Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:PlsX-like
Confidence and coverage
Confidence: | 100.0% | Coverage: | 88%
315 residues ( 88% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | T | R | L | T | L | A | L | D | V | M | G | G | D | F | G | P | S | V | T | V | P | A | A | L | Q | A | L | N | S | N | S | Q | L | T | L | L | L | V | G | N | S | D | A | I | T | P | L | L | A | K | A | D | F | E | Q | R | S | R | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ? |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | Q | I | I | P | A | Q | S | V | I | A | S | D | A | R | P | S | Q | A | I | R | A | S | R | G | S | S | M | R | V | A | L | E | L | V | K | E | G | R | A | Q | A | C | V | S | A | G | N | T | G | A | L | M | G | L | A | K | L | L | L | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | P | L | E | G | I | E | R | P | A | L | V | T | V | L | P | H | Q | Q | K | G | K | T | V | V | L | D | L | G | A | N | V | D | C | D | S | T | M | L | V | Q | F | A | I | M | G | S | V | L | A | E | E | V | V | E | I | P | N | P | R | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | A | L | L | N | I | G | E | E | E | V | K | G | L | D | S | I | R | D | A | S | A | V | L | K | T | I | P | S | I | N | Y | I | G | Y | L | E | A | N | E | L | L | T | G | K | T | D | V | L | V | C | D | G | F | T | G | N | V | T | L | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | T | M | E | G | V | V | R | M | F | L | S | L | L | K | S | Q | G | E | G | K | K | R | S | W | W | L | L | L | L | K | R | W | L | Q | K | S | L | T | R | R | F | S | H | L | N | P | D | Q | Y | N | G | A | C | L | L | G | L | R | G | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | .
Sequence |  | V | I | K | S | H | G | A | A | N | Q | R | A | F | A | V | A | I | E | Q | A | V | Q | A | V | Q | R | Q | V | P | Q | R | I | A | A | R | L | E | S | V | Y | P | A | G | F | E | L | L | D | G | G | K | S | G | T | L | R
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d1u7na_ |

### PDB 1u7n chain A

Region: 5 - 337
Aligned: 315
Modelled: 333
Confidence: 100.0%
Identity: 37%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: PlsX-like

Phyre2
2 |
| d1vi1a_ |

### PDB 1vi1 chain A

Region: 4 - 342
Aligned: 325
Modelled: 339
Confidence: 100.0%
Identity: 36%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: PlsX-like

Phyre2
3 |
| d1xcoa_ |

### PDB 1xco chain A

Region: 2 - 321
Aligned: 272
Modelled: 281
Confidence: 100.0%
Identity: 22%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: Phosphotransacetylase

Phyre2
4 |
| d2af4c1 |

### PDB 2af4 chain C domain 1

Region: 3 - 326
Aligned: 278
Modelled: 285
Confidence: 100.0%
Identity: 19%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: Phosphotransacetylase

Phyre2
5 |
| d1r5ja_ |

### PDB 1r5j chain A

Region: 2 - 327
Aligned: 279
Modelled: 281
Confidence: 100.0%
Identity: 22%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: Phosphotransacetylase

Phyre2
6 |
| c1ycoA_ |

### PDB 1yco chain A

Region: 3 - 327
Aligned: 256
Modelled: 261
Confidence: 100.0%
Identity: 16%
PDB header:transferase
Chain: A: PDB Molecule:branched-chain phosphotransacylase;
PDBTitle: crystal structure of a branched-chain phosphotransacylase from2 enterococcus faecalis v583

Phyre2
7 |
| c3tngA_ |

### PDB 3tng chain A

Region: 2 - 326
Aligned: 257
Modelled: 271
Confidence: 100.0%
Identity: 21%
PDB header:transferase
Chain: A: PDB Molecule:lmo1369 protein;
PDBTitle: the crystal structure of a possible phosphate acetyl/butaryl2 transferase from listeria monocytogenes egd-e.

Phyre2
8 |
| d1vmia_ |

### PDB 1vmi chain A

Region: 2 - 321
Aligned: 274
Modelled: 280
Confidence: 100.0%
Identity: 19%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: Phosphotransacetylase

Phyre2
9 |
| c1vmiA_ |

### PDB 1vmi chain A

Region: 2 - 321
Aligned: 274
Modelled: 280
Confidence: 100.0%
Identity: 19%
PDB header:transferase
Chain: A: PDB Molecule:putative phosphate acetyltransferase;
PDBTitle: crystal structure of putative phosphate acetyltransferase2 (np_416953.1) from escherichia coli k12 at 2.32 a resolution

Phyre2
10 |
| d1ptma_ |

### PDB 1ptm chain A

Region: 1 - 326
Aligned: 282
Modelled: 306
Confidence: 100.0%
Identity: 16%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: PdxA-like

Phyre2
11 |
| c1yxoB_ |

### PDB 1yxo chain B

Region: 4 - 327
Aligned: 280
Modelled: 292
Confidence: 100.0%
Identity: 20%
PDB header:oxidoreductase
Chain: B: PDB Molecule:4-hydroxythreonine-4-phosphate dehydrogenase 1;
PDBTitle: crystal structure of pyridoxal phosphate biosynthetic protein pdxa2 pa0593

Phyre2
12 |
| d1r8ka_ |

### PDB 1r8k chain A

Region: 5 - 327
Aligned: 266
Modelled: 281
Confidence: 100.0%
Identity: 17%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: PdxA-like

Phyre2
13 |
| c2hi1A_ |

### PDB 2hi1 chain A

Region: 5 - 230
Aligned: 217
Modelled: 217
Confidence: 98.4%
Identity: 20%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:4-hydroxythreonine-4-phosphate dehydrogenase 2;
PDBTitle: the structure of a putative 4-hydroxythreonine-4-phosphate2 dehydrogenase from salmonella typhimurium.

Phyre2
14 |
| d1qgoa_ |

### PDB 1qgo chain A

Region: 298 - 330
Aligned: 33
Modelled: 33
Confidence: 74.7%
Identity: 12%
Fold: Chelatase-like
Superfamily: Chelatase
Family: Cobalt chelatase CbiK

Phyre2
15 |
| d1gmla_ |

### PDB 1gml chain A

Region: 175 - 243
Aligned: 59
Modelled: 69
Confidence: 64.9%
Identity: 19%
Fold: The "swivelling" beta/beta/alpha domain
Superfamily: GroEL apical domain-like
Family: Group II chaperonin (CCT, TRIC), apical domain

Phyre2
16 |
| c2phjA_ |

### PDB 2phj chain A

Region: 14 - 185
Aligned: 146
Modelled: 148
Confidence: 56.6%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:5'-nucleotidase sure;
PDBTitle: crystal structure of sure protein from aquifex aeolicus

Phyre2
17 |
| c3qd5B_ |

### PDB 3qd5 chain B

Region: 1 - 123
Aligned: 86
Modelled: 111
Confidence: 56.0%
Identity: 23%
PDB header:isomerase
Chain: B: PDB Molecule:putative ribose-5-phosphate isomerase;
PDBTitle: crystal structure of a putative ribose-5-phosphate isomerase from2 coccidioides immitis solved by combined iodide ion sad and mr

Phyre2
18 |
| c3lyhB_ |

### PDB 3lyh chain B

Region: 298 - 326
Aligned: 29
Modelled: 29
Confidence: 55.8%
Identity: 17%
PDB header:lyase
Chain: B: PDB Molecule:cobalamin (vitamin b12) biosynthesis cbix protein;
PDBTitle: crystal structure of putative cobalamin (vitamin b12) biosynthesis2 cbix protein (yp_958415.1) from marinobacter aquaeolei vt8 at 1.60 a3 resolution

Phyre2
19 |
| c3gdwA_ |

### PDB 3gdw chain A

Region: 299 - 319
Aligned: 21
Modelled: 21
Confidence: 53.7%
Identity: 14%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sigma-54 interaction domain protein;
PDBTitle: crystal structure of sigma-54 interaction domain protein from2 enterococcus faecalis

Phyre2
20 |
| d1tjna_ |

### PDB 1tjn chain A

Region: 298 - 327
Aligned: 30
Modelled: 30
Confidence: 52.2%
Identity: 23%
Fold: Chelatase-like
Superfamily: Chelatase
Family: CbiX-like

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d1u7na_ |
|  | 100.0 | 37 | Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:PlsX-like
2 | d1vi1a_ |
|  | 100.0 | 36 | Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:PlsX-like
3 | d1xcoa_ |
|  | 100.0 | 22 | Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Phosphotransacetylase
4 | d2af4c1 |
|  | 100.0 | 19 | Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Phosphotransacetylase
5 | d1r5ja_ |
|  | 100.0 | 22 | Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Phosphotransacetylase
6 | c1ycoA_ |
|  | 100.0 | 16 | PDB header:transferase Chain: A: PDB Molecule:branched-chain phosphotransacylase; PDBTitle: crystal structure of a branched-chain phosphotransacylase from2 enterococcus faecalis v583
7 | c3tngA_ |
|  | 100.0 | 21 | PDB header:transferase Chain: A: PDB Molecule:lmo1369 protein; PDBTitle: the crystal structure of a possible phosphate acetyl/butaryl2 transferase from listeria monocytogenes egd-e.
8 | d1vmia_ |
|  | 100.0 | 19 | Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Phosphotransacetylase
9 | c1vmiA_ |
|  | 100.0 | 19 | PDB header:transferase Chain: A: PDB Molecule:putative phosphate acetyltransferase; PDBTitle: crystal structure of putative phosphate acetyltransferase2 (np_416953.1) from escherichia coli k12 at 2.32 a resolution
10 | d1ptma_ |
|  | 100.0 | 16 | Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:PdxA-like
11 | c1yxoB_ |
|  | 100.0 | 20 | PDB header:oxidoreductase Chain: B: PDB Molecule:4-hydroxythreonine-4-phosphate dehydrogenase 1; PDBTitle: crystal structure of pyridoxal phosphate biosynthetic protein pdxa2 pa0593
12 | d1r8ka_ |
|  | 100.0 | 17 | Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:PdxA-like
13 | c2hi1A_ |
|  | 98.4 | 20 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:4-hydroxythreonine-4-phosphate dehydrogenase 2; PDBTitle: the structure of a putative 4-hydroxythreonine-4-phosphate2 dehydrogenase from salmonella typhimurium.
14 | d1qgoa_ |
|  | 74.7 | 12 | Fold:Chelatase-like Superfamily:Chelatase Family:Cobalt chelatase CbiK
15 | d1gmla_ |
|  | 64.9 | 19 | Fold:The "swivelling" beta/beta/alpha domain Superfamily:GroEL apical domain-like Family:Group II chaperonin (CCT, TRIC), apical domain
16 | c2phjA_ |
|  | 56.6 | 18 | PDB header:hydrolase Chain: A: PDB Molecule:5'-nucleotidase sure; PDBTitle: crystal structure of sure protein from aquifex aeolicus
17 | c3qd5B_ |
|  | 56.0 | 23 | PDB header:isomerase Chain: B: PDB Molecule:putative ribose-5-phosphate isomerase; PDBTitle: crystal structure of a putative ribose-5-phosphate isomerase from2 coccidioides immitis solved by combined iodide ion sad and mr
18 | c3lyhB_ |
|  | 55.8 | 17 | PDB header:lyase Chain: B: PDB Molecule:cobalamin (vitamin b12) biosynthesis cbix protein; PDBTitle: crystal structure of putative cobalamin (vitamin b12) biosynthesis2 cbix protein (yp_958415.1) from marinobacter aquaeolei vt8 at 1.60 a3 resolution
19 | c3gdwA_ |
|  | 53.7 | 14 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:sigma-54 interaction domain protein; PDBTitle: crystal structure of sigma-54 interaction domain protein from2 enterococcus faecalis
20 | d1tjna_ |
|  | 52.2 | 23 | Fold:Chelatase-like Superfamily:Chelatase Family:CbiX-like
21 | c1tjnA_ |
| not modelled | 52.2 | 23 | PDB header:lyase Chain: A: PDB Molecule:sirohydrochlorin cobaltochelatase; PDBTitle: crystal structure of hypothetical protein af0721 from archaeoglobus2 fulgidus
22 | c2pjuD_ |
| not modelled | 52.0 | 21 | PDB header:transcription Chain: D: PDB Molecule:propionate catabolism operon regulatory protein; PDBTitle: crystal structure of propionate catabolism operon2 regulatory protein prpr
23 | d1kzyc2 |
| not modelled | 48.1 | 29 | Fold:BRCT domain Superfamily:BRCT domain Family:53BP1
24 | c2ja9A_ |
| not modelled | 46.9 | 14 | PDB header:rna-binding protein Chain: A: PDB Molecule:exosome complex exonuclease rrp40; PDBTitle: structure of the n-terminal deletion of yeast exosome2 component rrp40
25 | d1q3qa3 |
| not modelled | 43.6 | 19 | Fold:GroEL-intermediate domain like Superfamily:GroEL-intermediate domain like Family:Group II chaperonin (CCT, TRIC), intermediate domain
26 | d1j9ja_ |
| not modelled | 43.5 | 16 | Fold:SurE-like Superfamily:SurE-like Family:SurE-like
27 | d1wu2a3 |
| not modelled | 42.9 | 33 | Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MoeA central domain-like
28 | c2v4oB_ |
| not modelled | 42.2 | 18 | PDB header:hydrolase Chain: B: PDB Molecule:multifunctional protein sur e; PDBTitle: crystal structure of salmonella typhimurium sure at 2.752 angstrom resolution in monoclinic form
29 | c2xvzA_ |
| not modelled | 40.6 | 19 | PDB header:metal binding protein Chain: A: PDB Molecule:chelatase, putative; PDBTitle: cobalt chelatase cbik (periplasmatic) from desulvobrio2 vulgaris hildenborough (co-crystallized with cobalt)
30 | d1y5ea1 |
| not modelled | 39.5 | 16 | Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like
31 | d2pjua1 |
| not modelled | 38.5 | 22 | Fold:Chelatase-like Superfamily:PrpR receptor domain-like Family:PrpR receptor domain-like
32 | d1fuia2 |
| not modelled | 38.3 | 14 | Fold:FucI/AraA N-terminal and middle domains Superfamily:FucI/AraA N-terminal and middle domains Family:L-fucose isomerase, N-terminal and second domains
33 | d2ja9a2 |
| not modelled | 38.2 | 15 | Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I)
34 | d2ftsa3 |
| not modelled | 36.8 | 45 | Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MoeA central domain-like
35 | c3gx1A_ |
| not modelled | 35.4 | 10 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin1832 protein; PDBTitle: crystal structure of a domain of lin1832 from listeria innocua
36 | d3ct6a1 |
| not modelled | 35.2 | 29 | Fold:PTS system fructose IIA component-like Superfamily:PTS system fructose IIA component-like Family:DhaM-like
37 | d1uz5a3 |
| not modelled | 34.8 | 45 | Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MoeA central domain-like
38 | c3k93A_ |
| not modelled | 31.0 | 26 | PDB header:hydrolase Chain: A: PDB Molecule:phage related exonuclease; PDBTitle: crystal structure of phage related exonuclease (yp_719632.1) from2 haemophilus somnus 129pt at 2.15 a resolution
39 | d3b48a1 |
| not modelled | 30.1 | 24 | Fold:PTS system fructose IIA component-like Superfamily:PTS system fructose IIA component-like Family:DhaM-like
40 | c3imkA_ |
| not modelled | 29.7 | 22 | PDB header:metal binding protein Chain: A: PDB Molecule:putative molybdenum carrier protein; PDBTitle: crystal structure of putative molybdenum carrier protein (yp_461806.1)2 from syntrophus aciditrophicus sb at 1.45 a resolution
41 | d1pkpa1 |
| not modelled | 28.9 | 19 | Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Translational machinery components
42 | d2uube1 |
| not modelled | 28.3 | 24 | Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Translational machinery components
43 | d1iowa1 |
| not modelled | 28.0 | 21 | Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:D-Alanine ligase N-terminal domain
44 | c3se7A_ |
| not modelled | 26.7 | 11 | PDB header:ligase Chain: A: PDB Molecule:vana; PDBTitle: ancient vana
45 | c3lkzB_ |
| not modelled | 24.6 | 23 | PDB header:viral protein Chain: B: PDB Molecule:non-structural protein 5; PDBTitle: structural and functional analyses of a conserved hydrophobic pocket2 of flavivirus methyltransferase
46 | d1jlja_ |
| not modelled | 22.9 | 21 | Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like
47 | d1su1a_ |
| not modelled | 21.8 | 14 | Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like
48 | c1su1A_ |
| not modelled | 21.8 | 14 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein yfce; PDBTitle: structural and biochemical characterization of yfce, a2 phosphoesterase from e. coli
49 | c1p6gE_ |
| not modelled | 21.6 | 15 | PDB header:ribosome Chain: E: PDB Molecule:30s ribosomal protein s5; PDBTitle: real space refined coordinates of the 30s subunit fitted2 into the low resolution cryo-em map of the ef-g.gtp state3 of e. coli 70s ribosome
50 | c1jqsB_ |
| not modelled | 21.3 | 50 | PDB header:ribosome Chain: B: PDB Molecule:elongation factor g; PDBTitle: fitting of l11 protein and elongation factor g (domain g'2 and v) in the cryo-em map of e. coli 70s ribosome bound3 with ef-g and gmppcp, a nonhydrolysable gtp analog
51 | d2qale1 |
| not modelled | 21.2 | 19 | Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Translational machinery components
52 | c3i12A_ |
| not modelled | 20.4 | 17 | PDB header:ligase Chain: A: PDB Molecule:d-alanine-d-alanine ligase a; PDBTitle: the crystal structure of the d-alanyl-alanine synthetase a from2 salmonella enterica subsp. enterica serovar typhimurium str. lt2
53 | d1v4va_ |
| not modelled | 19.9 | 21 | Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:UDP-N-acetylglucosamine 2-epimerase
54 | d1a6db2 |
| not modelled | 19.8 | 14 | Fold:The "swivelling" beta/beta/alpha domain Superfamily:GroEL apical domain-like Family:Group II chaperonin (CCT, TRIC), apical domain
55 | d1assa_ |
| not modelled | 17.5 | 17 | Fold:The "swivelling" beta/beta/alpha domain Superfamily:GroEL apical domain-like Family:Group II chaperonin (CCT, TRIC), apical domain
56 | d1iqoa_ |
| not modelled | 17.2 | 14 | Fold:Hypothetical protein MTH1880 Superfamily:Hypothetical protein MTH1880 Family:Hypothetical protein MTH1880
57 | c2xcuC_ |
| not modelled | 17.2 | 16 | PDB header:transferase Chain: C: PDB Molecule:3-deoxy-d-manno-2-octulosonic acid transferase; PDBTitle: membrane-embedded monofunctional glycosyltransferase waaa of aquifex2 aeolicus, comlex with cmp
58 | c2xnkA_ |
| not modelled | 16.3 | 20 | PDB header:isomerase Chain: A: PDB Molecule:dna topoisomerase 2-binding protein 1; PDBTitle: structure and function of the rad9-binding region of the dna damage2 checkpoint adaptor topbp1
59 | c2e6gI_ |
| not modelled | 16.1 | 19 | PDB header:hydrolase Chain: I: PDB Molecule:5'-nucleotidase sure; PDBTitle: crystal structure of the stationary phase survival protein sure from2 thermus thermophilus hb8 in complex with phosphate
60 | c3qfnA_ |
| not modelled | 16.0 | 19 | PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of streptococcal asymmetric ap4a hydrolase and2 phosphodiesterase spr1479/saph in complex with inorganic phosphate
61 | c3af5A_ |
| not modelled | 15.7 | 26 | PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein ph1404; PDBTitle: the crystal structure of an archaeal cpsf subunit, ph1404 from2 pyrococcus horikoshii
62 | d1tqya1 |
| not modelled | 14.5 | 14 | Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related
63 | c2nqqA_ |
| not modelled | 14.0 | 50 | PDB header:biosynthetic protein Chain: A: PDB Molecule:molybdopterin biosynthesis protein moea; PDBTitle: moea r137q
64 | c3dcjA_ |
| not modelled | 13.6 | 22 | PDB header:transferase Chain: A: PDB Molecule:probable 5'-phosphoribosylglycinamide PDBTitle: crystal structure of glycinamide formyltransferase (purn)2 from mycobacterium tuberculosis in complex with 5-methyl-5,3 6,7,8-tetrahydrofolic acid derivative
65 | c2xzmE_ |
| not modelled | 13.4 | 20 | PDB header:ribosome Chain: E: PDB Molecule:ribosomal protein s5 containing protein; PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 1
66 | c3lfhF_ |
| not modelled | 13.0 | 19 | PDB header:transferase Chain: F: PDB Molecule:phosphotransferase system, mannose/fructose-specific PDBTitle: crystal structure of manxa from thermoanaerobacter tengcongensis
67 | c2fu3A_ |
| not modelled | 13.0 | 27 | PDB header:biosynthetic protein/structural protein Chain: A: PDB Molecule:gephyrin; PDBTitle: crystal structure of gephyrin e-domain
68 | c2q5cA_ |
| not modelled | 12.9 | 18 | PDB header:transcription Chain: A: PDB Molecule:ntrc family transcriptional regulator; PDBTitle: crystal structure of ntrc family transcriptional regulator from2 clostridium acetobutylicum
69 | d1b77a2 |
| not modelled | 12.5 | 19 | Fold:DNA clamp Superfamily:DNA clamp Family:DNA polymerase processivity factor
70 | c3iprC_ |
| not modelled | 12.5 | 35 | PDB header:transferase Chain: C: PDB Molecule:pts system, iia component; PDBTitle: crystal structure of the enterococcus faecalis gluconate2 specific eiia phosphotransferase system component
71 | c3oryA_ |
| not modelled | 12.4 | 18 | PDB header:hydrolase Chain: A: PDB Molecule:flap endonuclease 1; PDBTitle: crystal structure of flap endonuclease 1 from hyperthermophilic2 archaeon desulfurococcus amylolyticus
72 | c2ow8f_ |
| not modelled | 12.4 | 28 | PDB header:ribosome Chain: F: PDB Molecule: PDBTitle: crystal structure of a 70s ribosome-trna complex reveals functional2 interactions and rearrangements. this file, 2ow8, contains the 30s3 ribosome subunit, two trna, and mrna molecules. 50s ribosome subunit4 is in the file 1vsa.
73 | d1lqta1 |
| not modelled | 12.1 | 9 | Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:C-terminal domain of adrenodoxin reductase-like
74 | d2nn6g3 |
| not modelled | 11.5 | 13 | Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I)
75 | d1kfia2 |
| not modelled | 11.3 | 25 | Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains
76 | c3bbnE_ |
| not modelled | 10.6 | 31 | PDB header:ribosome Chain: E: PDB Molecule:ribosomal protein s5; PDBTitle: homology model for the spinach chloroplast 30s subunit2 fitted to 9.4a cryo-em map of the 70s chlororibosome.
77 | d1oaoa_ |
| not modelled | 10.5 | 27 | Fold:Prismane protein-like Superfamily:Prismane protein-like Family:Carbon monoxide dehydrogenase
78 | c2yw3E_ |
| not modelled | 10.5 | 20 | PDB header:lyase Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3- PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1
79 | d1o6ca_ |
| not modelled | 10.4 | 14 | Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:UDP-N-acetylglucosamine 2-epimerase
80 | c2jfsA_ |
| not modelled | 10.4 | 12 | PDB header:hydrolase Chain: A: PDB Molecule:ser-thr phosphatase mspp; PDBTitle: crystal structure of the ppm ser-thr phosphatase mspp from2 mycobacterium smegmatis in complex with cacodylate
81 | d2oqea3 |
| not modelled | 10.4 | 15 | Fold:Cystatin-like Superfamily:Amine oxidase N-terminal region Family:Amine oxidase N-terminal region
82 | c1eg0B_ |
| not modelled | 10.2 | 22 | PDB header:ribosome PDB COMPND:
83 | d1e4ea1 |
| not modelled | 10.2 | 18 | Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:D-Alanine ligase N-terminal domain
84 | d1o1xa_ |
| not modelled | 10.0 | 11 | Fold:Ribose/Galactose isomerase RpiB/AlsB Superfamily:Ribose/Galactose isomerase RpiB/AlsB Family:Ribose/Galactose isomerase RpiB/AlsB
85 | c2p3qA_ |
| not modelled | 9.9 | 22 | PDB header:viral protein,transferase Chain: A: PDB Molecule:type ii methyltransferase; PDBTitle: crystal structure of dengue methyltransferase in complex with gpppg2 and s-adenosyl-l-homocysteine
86 | d2bfwa1 |
| not modelled | 9.9 | 14 | Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:Glycosyl transferases group 1
87 | c3hp7A_ |
| not modelled | 9.9 | 22 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hemolysin, putative; PDBTitle: putative hemolysin from streptococcus thermophilus.
88 | c1uz5A_ |
| not modelled | 9.6 | 30 | PDB header:molybdopterin biosynthesis Chain: A: PDB Molecule:402aa long hypothetical molybdopterin PDBTitle: the crystal structure of molybdopterin biosynthesis moea2 protein from pyrococcus horikosii
89 | c2kpmA_ |
| not modelled | 9.6 | 10 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of uncharacterized protein from gene2 locus ne0665 of nitrosomonas europaea. northeast structural3 genomics target ner103a
90 | c1wu2B_ |
| not modelled | 9.6 | 31 | PDB header:structural genomics,biosynthetic protein Chain: B: PDB Molecule:molybdopterin biosynthesis moea protein; PDBTitle: crystal structure of molybdopterin biosynthesis moea2 protein from pyrococcus horikoshii ot3
91 | c2jh3C_ |
| not modelled | 9.5 | 21 | PDB header:ribosomal protein Chain: C: PDB Molecule:ribosomal protein s2-related protein; PDBTitle: the crystal structure of dr2241 from deinococcus2 radiodurans at 1.9 a resolution reveals a multi-domain3 protein with structural similarity to chelatases but also4 with two additional novel domains
92 | c1b43A_ |
| not modelled | 9.3 | 16 | PDB header:transferase Chain: A: PDB Molecule:protein (fen-1); PDBTitle: fen-1 from p. furiosus
93 | c2wa1A_ |
| not modelled | 9.2 | 20 | PDB header:transferase Chain: A: PDB Molecule:non-structural protein 5; PDBTitle: structure of the methyltransferase domain from modoc virus,2 a flavivirus with no known vector (nkv)
94 | d1xo1a1 |
| not modelled | 9.1 | 10 | Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain
95 | c3s5pA_ |
| not modelled | 8.9 | 13 | PDB header:isomerase Chain: A: PDB Molecule:ribose 5-phosphate isomerase; PDBTitle: crystal structure of ribose-5-phosphate isomerase b rpib from giardia2 lamblia
96 | d1p90a_ |
| not modelled | 8.9 | 17 | Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:Nitrogenase accessory factor
97 | d1pdoa_ |
| not modelled | 8.8 | 25 | Fold:PTS system fructose IIA component-like Superfamily:PTS system fructose IIA component-like Family:EIIA-man component-like
98 | c3mtqA_ |
| not modelled | 8.6 | 24 | PDB header:transferase Chain: A: PDB Molecule:putative phosphoenolpyruvate-dependent sugar PDBTitle: crystal structure of a putative phosphoenolpyruvate-dependent sugar2 phosphotransferase system (pts) permease (kpn_04802) from klebsiella3 pneumoniae subsp. pneumoniae mgh 78578 at 1.70 a resolution
99 | d3pmga2 |
| not modelled | 8.4 | 42 | Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains

Binding site prediction |

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If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0