Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	A	P	S	Q	V	L	K	I	R	R	P	D	D	W	H	L	H	L	R	D	G	D	M	L	K	T	V	V	P	Y	T	S	E	I	Y	G	R	A	I	V	M	P	N	L	A	P	P	V	T	T	V	E	A	A	V	A	Y	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	R	I	L	D	A	V	P	A	G	H	D	F	T	P	L	M	T	C	Y	L	T	D	S	L	D	P	N	E	L	E	R	G	F	N	E	G	V	F	T	A	A	K	L	Y	P	A	N	A	T	T	N	S	S	H	G	V	T	S	I
Secondary structure
SS confidence
Disorder																																																				?	?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	A	I	M	P	V	L	E	R	M	E	K	I	G	M	P	L	L	V	H	G	E	V	T	H	A	D	I	D	I	F	D	R	E	A	R	F	I	E	S	V	M	E	P	L	R	Q	R	L	T	A	L	K	V	V	F	E	H	I	T
Secondary structure
SS confidence
Disorder																								?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	K	D	A	A	D	Y	V	R	D	G	N	E	R	L	A	A	T	I	T	P	Q	H	L	M	F	N	R	N	H	M	L	V	G	G	V	R	P	H	L	Y	C	L	P	I	L	K	R	N	I	H	Q	Q	A	L	R	E	L	V	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		S	G	F	N	R	V	F	L	G	T	D	S	A	P	H	A	R	H	R	K	E	S	S	C	G	C	A	G	C	F	N	A	P	T	A	L	G	S	Y	A	T	V	F	E	E	M	N	A	L	Q	H	F	E	A	F	C	S	V	N	G
Secondary structure
SS confidence
Disorder																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.
Sequence		P	Q	F	Y	G	L	P	V	N	D	T	F	I	E	L	V	R	E	E	Q	Q	V	A	E	S	I	A	L	T	D	D	T	L	V	P	F	L	A	G	E	T	V	R	W	S	V	K	Q
Secondary structure
SS confidence
Disorder																												?	?	?													?	?	?	?		?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2eg6 chain A domain 1 Region: 5 - 347 Aligned: 342 Modelled: 343 Confidence: 100.0% Identity: 99% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Dihydroorotase Phyre2 PDB 3jze chain C Region: 5 - 348 Aligned: 343 Modelled: 344 Confidence: 100.0% Identity: 87% PDB header:hydrolase Chain: C: PDB Molecule:dihydroorotase; PDBTitle: 1.8 angstrom resolution crystal structure of dihydroorotase (pyrc)2 from salmonella enterica subsp. enterica serovar typhimurium str. lt2 Phyre2 PDB 3pnu chain A Region: 5 - 347 Aligned: 327 Modelled: 343 Confidence: 100.0% Identity: 38% PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: 2.4 angstrom crystal structure of dihydroorotase (pyrc) from2 campylobacter jejuni. Phyre2 PDB 1k1d chain A domain 2 Region: 12 - 312 Aligned: 291 Modelled: 301 Confidence: 100.0% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Hydantoinase (dihydropyrimidinase), catalytic domain Phyre2 PDB 1gkr chain A domain 2 Region: 12 - 311 Aligned: 287 Modelled: 300 Confidence: 100.0% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Hydantoinase (dihydropyrimidinase), catalytic domain Phyre2 PDB 1nfg chain A domain 2 Region: 12 - 312 Aligned: 290 Modelled: 301 Confidence: 100.0% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Hydantoinase (dihydropyrimidinase), catalytic domain Phyre2 PDB 1yny chain A domain 2 Region: 12 - 312 Aligned: 292 Modelled: 301 Confidence: 100.0% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Hydantoinase (dihydropyrimidinase), catalytic domain Phyre2 PDB 2fvk chain A domain 2 Region: 12 - 312 Aligned: 298 Modelled: 301 Confidence: 100.0% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Hydantoinase (dihydropyrimidinase), catalytic domain Phyre2 PDB 1m7j chain A domain 3 Region: 12 - 309 Aligned: 289 Modelled: 298 Confidence: 100.0% Identity: 11% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: D-aminoacylase, catalytic domain Phyre2 PDB 2ftw chain A domain 2 Region: 11 - 311 Aligned: 291 Modelled: 301 Confidence: 100.0% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Hydantoinase (dihydropyrimidinase), catalytic domain Phyre2 PDB 1gkp chain A domain 2 Region: 13 - 313 Aligned: 290 Modelled: 296 Confidence: 100.0% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Hydantoinase (dihydropyrimidinase), catalytic domain Phyre2 PDB 1kcx chain A domain 2 Region: 11 - 311 Aligned: 292 Modelled: 297 Confidence: 100.0% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Hydantoinase (dihydropyrimidinase), catalytic domain Phyre2 PDB 2vr2 chain A Region: 5 - 347 Aligned: 333 Modelled: 339 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: human dihydropyrimidinase Phyre2 PDB 3dc8 chain B Region: 5 - 347 Aligned: 330 Modelled: 338 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:dihydropyrimidinase; PDBTitle: crystal structure of dihydropyrimidinase from sinorhizobium meliloti Phyre2 PDB 2fvm chain A Region: 5 - 347 Aligned: 333 Modelled: 337 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: crystal structure of dihydropyrimidinase from saccharomyces kluyveri2 in complex with the reaction product n-carbamyl-beta-alanine Phyre2 PDB 2ftw chain A Region: 5 - 347 Aligned: 334 Modelled: 343 Confidence: 100.0% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidine amidohydrolase; PDBTitle: crystal structure of dihydropyrimidinase from dictyostelium discoideum Phyre2 PDB 2gse chain C Region: 5 - 347 Aligned: 335 Modelled: 343 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: C: PDB Molecule:dihydropyrimidinase-related protein 2; PDBTitle: crystal structure of human dihydropyrimidinease-like 2 Phyre2 PDB 1gkp chain D Region: 5 - 347 Aligned: 331 Modelled: 338 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: D: PDB Molecule:hydantoinase; PDBTitle: d-hydantoinase (dihydropyrimidinase) from thermus sp. in2 space group c2221 Phyre2 PDB 1gkr chain A Region: 5 - 347 Aligned: 329 Modelled: 343 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:non-atp dependent l-selective hydantoinase; PDBTitle: l-hydantoinase (dihydropyrimidinase) from arthrobacter2 aurescens Phyre2 PDB 3hm7 chain A Region: 5 - 347 Aligned: 330 Modelled: 337 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:allantoinase; PDBTitle: crystal structure of allantoinase from bacillus halodurans c-125 Phyre2 1 d2eg6a1 2 c3jzeC_ 3 c3pnuA_ 4 d1k1da2 5 d1gkra2 6 d1nfga2 7 d1ynya2 8 d2fvka2 9 d1m7ja3 10 d2ftwa2 11 d1gkpa2 12 d1kcxa2 13 c2vr2A_ 14 c3dc8B_ 15 c2fvmA_ 16 c2ftwA_ 17 c2gseC_ 18 c1gkpD_ 19 c1gkrA_ 20 c3hm7A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2eg6a1 100.0 99 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Dihydroorotase 2 c3jzeC_ 100.0 87 PDB header:hydrolase Chain: C: PDB Molecule:dihydroorotase; PDBTitle: 1.8 angstrom resolution crystal structure of dihydroorotase (pyrc)2 from salmonella enterica subsp. enterica serovar typhimurium str. lt2 3 c3pnuA_ 100.0 38 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: 2.4 angstrom crystal structure of dihydroorotase (pyrc) from2 campylobacter jejuni. 4 d1k1da2 100.0 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 5 d1gkra2 100.0 17 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 6 d1nfga2 100.0 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 7 d1ynya2 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 8 d2fvka2 100.0 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 9 d1m7ja3 100.0 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:D-aminoacylase, catalytic domain 10 d2ftwa2 100.0 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 11 d1gkpa2 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 12 d1kcxa2 100.0 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 13 c2vr2A_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: human dihydropyrimidinase 14 c3dc8B_ 100.0 16 PDB header:hydrolase Chain: B: PDB Molecule:dihydropyrimidinase; PDBTitle: crystal structure of dihydropyrimidinase from sinorhizobium meliloti 15 c2fvmA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: crystal structure of dihydropyrimidinase from saccharomyces kluyveri2 in complex with the reaction product n-carbamyl-beta-alanine 16 c2ftwA_ 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidine amidohydrolase; PDBTitle: crystal structure of dihydropyrimidinase from dictyostelium discoideum 17 c2gseC_ 100.0 16 PDB header:hydrolase Chain: C: PDB Molecule:dihydropyrimidinase-related protein 2; PDBTitle: crystal structure of human dihydropyrimidinease-like 2 18 c1gkpD_ 100.0 15 PDB header:hydrolase Chain: D: PDB Molecule:hydantoinase; PDBTitle: d-hydantoinase (dihydropyrimidinase) from thermus sp. in2 space group c2221 19 c1gkrA_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:non-atp dependent l-selective hydantoinase; PDBTitle: l-hydantoinase (dihydropyrimidinase) from arthrobacter2 aurescens 20 c3hm7A_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:allantoinase; PDBTitle: crystal structure of allantoinase from bacillus halodurans c-125 21 c1k1dF_ not modelled 100.0 17 PDB header:hydrolase Chain: F: PDB Molecule:d-hydantoinase; PDBTitle: crystal structure of d-hydantoinase 22 c1nfgA_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:d-hydantoinase; PDBTitle: structure of d-hydantoinase 23 c2z00A_ not modelled 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of dihydroorotase from thermus thermophilus 24 c3griB_ not modelled 100.0 19 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: the crystal structure of a dihydroorotase from staphylococcus aureus 25 c3e74D_ not modelled 100.0 15 PDB header:hydrolase Chain: D: PDB Molecule:allantoinase; PDBTitle: crystal structure of e. coli allantoinase with iron ions at2 the metal center 26 c2gwnA_ not modelled 100.0 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:dihydroorotase; PDBTitle: the structure of putative dihydroorotase from porphyromonas2 gingivalis. 27 c3mpgB_ not modelled 100.0 19 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: dihydroorotase from bacillus anthracis 28 c3d6nA_ not modelled 100.0 22 PDB header:hydrolase/transferase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase 29 d1xrta2 not modelled 100.0 22 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 30 c1xrfA_ not modelled 100.0 24 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: the crystal structure of a novel, latent dihydroorotase from aquifex2 aeolicus at 1.7 a resolution 31 c3la4A_ not modelled 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:urease; PDBTitle: crystal structure of the first plant urease from jack bean (canavalia2 ensiformis) 32 d1o12a2 not modelled 99.9 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain 33 d1i0da_ not modelled 99.9 10 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 34 c1pscA_ not modelled 99.9 10 PDB header:hydrolase Chain: A: PDB Molecule:phosphotriesterase; PDBTitle: phosphotriesterase from pseudomonas diminuta 35 c3pnzD_ not modelled 99.9 16 PDB header:hydrolase Chain: D: PDB Molecule:phosphotriesterase family protein; PDBTitle: crystal structure of the lactonase lmo2620 from listeria monocytogenes 36 d2d2ja1 not modelled 99.9 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 37 d4ubpc2 not modelled 99.9 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:alpha-subunit of urease, catalytic domain 38 d1onwa2 not modelled 99.9 9 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Isoaspartyl dipeptidase, catalytic domain 39 c3msrA_ not modelled 99.9 9 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolases; PDBTitle: the crystal structure of an amidohydrolase from mycoplasma synoviae 40 c3e0lB_ not modelled 99.8 13 PDB header:hydrolase Chain: B: PDB Molecule:guanine deaminase; PDBTitle: computationally designed ammelide deaminase 41 d2icsa2 not modelled 99.8 8 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenine deaminase-like 42 c2vunC_ not modelled 99.8 13 PDB header:hydrolase Chain: C: PDB Molecule:enamidase; PDBTitle: the crystal structure of enamidase at 1.9 a resolution - a2 new member of the amidohydrolase superfamily 43 c1p1mA_ not modelled 99.8 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein tm0936; PDBTitle: structure of thermotoga maritima amidohydrolase tm09362 bound to ni and methionine 44 c3nqbB_ not modelled 99.7 10 PDB header:hydrolase Chain: B: PDB Molecule:adenine deaminase 2; PDBTitle: crystal structure of adenine deaminase from agrobacterium tumefaciens2 (str. c 58) 45 c3lsbA_ not modelled 99.7 11 PDB header:hydrolase Chain: A: PDB Molecule:triazine hydrolase; PDBTitle: crystal structure of the mutant e241q of atrazine chlorohydrolase trzn2 from arthrobacter aurescens tc1 complexed with zinc and ametrin 46 c2ubpC_ not modelled 99.7 13 PDB header:hydrolase Chain: C: PDB Molecule:protein (urease alpha subunit); PDBTitle: structure of native urease from bacillus pasteurii 47 c2aqoB_ not modelled 99.7 13 PDB header:hydrolase Chain: B: PDB Molecule:isoaspartyl dipeptidase; PDBTitle: crystal structure of e. coli isoaspartyl dipeptidase mutant e77q 48 c3gnhA_ not modelled 99.7 12 PDB header:hydrolase Chain: A: PDB Molecule:l-lysine, l-arginine carboxypeptidase cc2672; PDBTitle: crystal structure of l-lysine, l-arginine carboxypeptidase cc2672 from2 caulobacter crescentus cb15 complexed with n-methyl phosphonate3 derivative of l-arginine. 49 c2pajA_ not modelled 99.7 11 PDB header:hydrolase Chain: A: PDB Molecule:putative cytosine/guanine deaminase; PDBTitle: crystal structure of an amidohydrolase from an environmental sample of2 sargasso sea 50 c3hpaB_ not modelled 99.7 11 PDB header:hydrolase Chain: B: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of an amidohydrolase gi:44264246 from an2 evironmental sample of sargasso sea 51 c2vc7A_ not modelled 99.7 11 PDB header:hydrolase Chain: A: PDB Molecule:aryldialkylphosphatase; PDBTitle: structural basis for natural lactonase and promiscuous2 phosphotriesterase activities 52 c1r9yA_ not modelled 99.7 13 PDB header:hydrolase Chain: A: PDB Molecule:cytosine deaminase; PDBTitle: bacterial cytosine deaminase d314a mutant. 53 d2p9ba2 not modelled 99.7 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 54 c2r8cB_ not modelled 99.7 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative amidohydrolase; PDBTitle: crystal structure of uncharacterized protein eaj56179 55 c2ogjB_ not modelled 99.6 12 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of a dihydroorotase 56 c2q09A_ not modelled 99.6 11 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: crystal structure of imidazolonepropionase from environmental sample2 with bound inhibitor 3-(2,5-dioxo-imidazolidin-4-yl)-propionic acid 57 c3ighX_ not modelled 99.6 15 PDB header:hydrolase Chain: X: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from pyrococcus horikoshii ot3 58 c2gokA_ not modelled 99.6 11 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: crystal structure of the imidazolonepropionase from agrobacterium2 tumefaciens at 1.87 a resolution 59 c1e9yB_ not modelled 99.6 14 PDB header:hydrolase Chain: B: PDB Molecule:urease subunit beta; PDBTitle: crystal structure of helicobacter pylori urease in complex with2 acetohydroxamic acid 60 c2oodA_ not modelled 99.6 12 PDB header:hydrolase Chain: A: PDB Molecule:blr3880 protein; PDBTitle: crystal structure of guanine deaminase from bradyrhizobium japonicum 61 d1xwya1 not modelled 99.6 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 62 c2qt3A_ not modelled 99.6 11 PDB header:hydrolase Chain: A: PDB Molecule:n-isopropylammelide isopropyl amidohydrolase; PDBTitle: crystal structure of n-isopropylammelide isopropylaminohydrolase atzc2 from pseudomonas sp. strain adp complexed with zn 63 c3be7B_ not modelled 99.6 13 PDB header:hydrolase Chain: B: PDB Molecule:zn-dependent arginine carboxypeptidase; PDBTitle: crystal structure of zn-dependent arginine carboxypeptidase 64 c2i9uA_ not modelled 99.6 13 PDB header:hydrolase Chain: A: PDB Molecule:cytosine/guanine deaminase related protein; PDBTitle: crystal structure of guanine deaminase from c. acetobutylicum with2 bound guanine in the active site 65 c2bb0A_ not modelled 99.6 12 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: structure of imidazolonepropionase from bacillus subtilis 66 d1bf6a_ not modelled 99.6 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 67 d1ra0a2 not modelled 99.6 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Cytosine deaminase catalytic domain 68 c2p9bA_ not modelled 99.5 12 PDB header:hydrolase Chain: A: PDB Molecule:possible prolidase; PDBTitle: crystal structure of putative prolidase from2 bifidobacterium longum 69 c3feqB_ not modelled 99.5 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative amidohydrolase; PDBTitle: crystal structure of uncharacterized protein eah89906 70 d1zzma1 not modelled 99.5 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 71 c2icsA_ not modelled 99.5 9 PDB header:hydrolase Chain: A: PDB Molecule:adenine deaminase; PDBTitle: crystal structure of an adenine deaminase 72 c3gipB_ not modelled 99.5 14 PDB header:hydrolase Chain: B: PDB Molecule:n-acyl-d-glutamate deacylase; PDBTitle: crystal structure of n-acyl-d-glutamate deacylase from2 bordetella bronchiseptica complexed with zinc, acetate and3 formate ions. 73 c3lnpA_ not modelled 99.5 12 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase family protein olei01672_1_465; PDBTitle: crystal structure of amidohydrolase family protein2 olei01672_1_465 from oleispira antarctica 74 c2p50C_ not modelled 99.5 11 PDB header:hydrolase Chain: C: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase; PDBTitle: crystal structure of n-acetyl-d-glucosamine-6-phosphate deacetylase2 liganded with zn 75 c3etkA_ not modelled 99.5 16 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from pyrococcus furiosus 76 c1fwcC_ not modelled 99.4 13 PDB header:hydrolase Chain: C: PDB Molecule:urease; PDBTitle: klebsiella aerogenes urease, c319a variant at ph 8.5 77 c3rcmA_ not modelled 99.4 17 PDB header:hydrolase Chain: A: PDB Molecule:tatd family hydrolase; PDBTitle: crystal structure of efi target 500140:tatd family hydrolase from2 pseudomonas putida 78 c3ooqC_ not modelled 99.4 12 PDB header:hydrolase Chain: C: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of amidohydrolase from thermotoga maritima msb8 79 c1rjqA_ not modelled 99.4 11 PDB header:hydrolase Chain: A: PDB Molecule:d-aminoacylase; PDBTitle: the crystal structure of the d-aminoacylase mutant d366a 80 c3mduA_ not modelled 99.4 13 PDB header:hydrolase Chain: A: PDB Molecule:n-formimino-l-glutamate iminohydrolase; PDBTitle: the structure of n-formimino-l-glutamate iminohydrolase from2 pseudomonas aeruginosa complexed with n-guanidino-l-glutamate 81 d2uz9a2 not modelled 99.4 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 82 d2paja2 not modelled 99.4 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 83 c2qs8A_ not modelled 99.4 11 PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of a xaa-pro dipeptidase with bound2 methionine in the active site 84 c3f4cA_ not modelled 99.4 14 PDB header:hydrolase Chain: A: PDB Molecule:organophosphorus hydrolase; PDBTitle: crystal structure of organophosphorus hydrolase from geobacillus2 stearothermophilus strain 10, with glycerol bound 85 d3be7a2 not modelled 99.4 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 86 d1xrta1 not modelled 99.4 11 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase) 87 d1nfga1 not modelled 99.4 13 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase) 88 c2zc1A_ not modelled 99.3 12 PDB header:hydrolase Chain: A: PDB Molecule:phosphotriesterase; PDBTitle: organophosphorus hydrolase from deinococcus radiodurans 89 c2vhlB_ not modelled 99.3 11 PDB header:hydrolase Chain: B: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase; PDBTitle: the three-dimensional structure of the n-acetylglucosamine-2 6-phosphate deacetylase from bacillus subtilis 90 c2imrA_ not modelled 99.3 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein dr_0824; PDBTitle: crystal structure of amidohydrolase dr_0824 from2 deinococcus radiodurans 91 d1yixa1 not modelled 99.3 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 92 c3egjA_ not modelled 99.3 10 PDB header:hydrolase Chain: A: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase; PDBTitle: n-acetylglucosamine-6-phosphate deacetylase from vibrio cholerae. 93 d2imra2 not modelled 99.3 18 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:DR0824-like 94 d2r8ca2 not modelled 99.3 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 95 c2gzxB_ not modelled 99.2 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative tatd related dnase; PDBTitle: crystal structure of the tatd deoxyribonuclease mw0446 from2 staphylococcus aureus. northeast structural genomics consortium3 target zr237. 96 d1j6oa_ not modelled 99.2 18 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 97 c1o12B_ not modelled 99.2 13 PDB header:hydrolase Chain: B: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase; PDBTitle: crystal structure of n-acetylglucosamine-6-phosphate2 deacetylase (tm0814) from thermotoga maritima at 2.5 a3 resolution 98 d2bb0a2 not modelled 99.1 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 99 c2y1hA_ not modelled 99.1 16 PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn3; PDBTitle: crystal structure of the human tatd-domain protein 3 (tatdn3) 100 d2i9ua2 not modelled 99.1 17 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 101 d2ooda2 not modelled 99.1 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 102 d2qs8a2 not modelled 99.0 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 103 d2q09a2 not modelled 99.0 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 104 d1p1ma2 not modelled 98.9 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 105 d2puza2 not modelled 98.9 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 106 d2dvta1 not modelled 98.8 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 107 d2ffia1 not modelled 98.8 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 108 d1gkra1 not modelled 98.8 20 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase) 109 c2wm1A_ not modelled 98.8 19 PDB header:lyase Chain: A: PDB Molecule:2-amino-3-carboxymuconate-6-semialdehyde PDBTitle: the crystal structure of human alpha-amino-beta-2 carboxymuconate-epsilon-semialdehyde decarboxylase in3 complex with 1,3- dihydroxyacetonephosphate suggests a4 regulatory link between nad synthesis and glycolysis 110 c3gg7A_ not modelled 98.8 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized metalloprotein; PDBTitle: crystal structure of an uncharacterized metalloprotein from2 deinococcus radiodurans 111 c3k2gA_ not modelled 98.7 13 PDB header:resiniferatoxin binding protein Chain: A: PDB Molecule:resiniferatoxin-binding, phosphotriesterase- PDBTitle: crystal structure of a resiniferatoxin-binding protein from2 rhodobacter sphaeroides 112 d2gwga1 not modelled 98.6 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 113 c3irsB_ not modelled 98.6 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein bb4693; PDBTitle: crystal structure of uncharacterized tim-barrel protein bb4693 from2 bordetella bronchiseptica 114 c3guwB_ not modelled 98.6 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein af_1765; PDBTitle: crystal structure of the tatd-like protein (af1765) from2 archaeoglobus fulgidus, northeast structural genomics3 consortium target gr121 115 c2qahA_ not modelled 98.6 14 PDB header:hydrolase Chain: A: PDB Molecule:2-pyrone-4,6-dicarboxylic acid hydrolase; PDBTitle: crystal structure of the 2-pyrone-4,6-dicarboxylic acid2 hydrolase from sphingomonas paucimobilis 116 c3cjpA_ not modelled 98.5 13 PDB header:hydrolase Chain: A: PDB Molecule:predicted amidohydrolase, dihydroorotase family; PDBTitle: crystal structure of an uncharacterized amidohydrolase cac3332 from2 clostridium acetobutylicum 117 c3ij6A_ not modelled 98.5 15 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from lactobacillus acidophilus 118 c3rhgA_ not modelled 98.3 11 PDB header:hydrolase Chain: A: PDB Molecule:putative phophotriesterase; PDBTitle: crystal structure of amidohydrolase pmi1525 (target efi-500319) from2 proteus mirabilis hi4320 119 d2f6ka1 not modelled 98.3 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 120 c3nurA_ not modelled 98.2 16 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of a putative amidohydrolase from staphylococcus2 aureus

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0