Phyre 2 Results for P08401

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Email | l.a.kelley@imperial.ac.uk
Description | P08401
Date | Thu Jan 5 11:01:29 GMT 2012
Unique Job ID | 0e99a62ab29891d4

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c3d36B_
Top template information
PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:sporulation kinase b; PDBTitle: how to switch off a histidine kinase: crystal structure of2 geobacillus stearothermophilus kinb with the inhibitor sda
Confidence and coverage
Confidence: | 100.0% | Coverage: | 45%
214 residues ( 45% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
412 residues ( 87%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | R | I | G | M | R | L | L | L | G | Y | F | L | L | V | A | V | A | A | W | F | V | L | A | I | F | V | K | E | V | K | P | G | V | R | R | A | T | E | G | T | L | I | D | T | A | T | L | L | A | E | L | A | R | P | D | L | L | S | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | D | P | T | H | G | Q | L | A | Q | A | F | N | Q | L | Q | H | R | P | F | R | A | N | I | G | G | I | N | K | V | R | N | E | Y | H | V | Y | M | T | D | A | Q | G | K | V | L | F | D | S | A | N | K | A | V | G | Q | D | Y | S | R | W
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | N | D | V | W | L | T | L | R | G | Q | Y | G | A | R | S | T | L | Q | N | P | A | D | P | E | S | S | V | M | Y | V | A | A | P | I | M | D | G | S | R | L | I | G | V | L | S | V | G | K | P | N | A | A | M | A | P | V | I | K | R | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  | ? | ? | ? | ? |  |  | ? | ? |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | E | R | R | I | L | W | A | S | A | I | L | L | G | I | A | L | V | I | G | A | G | M | V | W | W | I | N | R | S | I | A | R | L | T | R | Y | A | D | S | V | T | D | N | K | P | V | P | L | P | D | L | G | S | S | E | L | R | K | L | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | Q | A | L | E | S | M | R | V | K | L | E | G | K | N | Y | I | E | Q | Y | V | Y | A | L | T | H | E | L | K | S | P | L | A | A | I | R | G | A | A | E | I | L | R | E | G | P | P | P | E | V | V | A | R | F | T | D | N | I | L | T | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | N | A | R | M | Q | A | L | V | E | T | L | L | R | Q | A | R | L | E | N | R | Q | E | V | V | L | T | A | V | D | V | A | A | L | F | R | R | V | S | E | A | R | T | V | Q | L | A | E | K | K | I | T | L | H | V | T | P | T | E | V | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | V | A | A | E | P | A | L | L | E | Q | A | L | G | N | L | L | D | N | A | I | D | F | T | P | E | S | G | C | I | T | L | S | A | E | V | D | Q | E | H | V | T | L | K | V | L | D | T | G | S | G | I | P | D | Y | A | L | S | R | I | F
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | .
Sequence |  | E | R | F | Y | S | L | P | R | A | N | G | Q | K | S | S | G | L | G | L | A | F | V | S | E | V | A | R | L | F | N | G | E | V | T | L | R | N | V | Q | E | G | G | V | L | A | S | L | R | L | H | R | H | F | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c3d36B_ |

### PDB 3d36 chain B

Region: 251 - 470
Aligned: 214
Modelled: 220
Confidence: 100.0%
Identity: 22%
PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:sporulation kinase b;
PDBTitle: how to switch off a histidine kinase: crystal structure of2 geobacillus stearothermophilus kinb with the inhibitor sda

Phyre2
2 |
| c3d2rB_ |

### PDB 3d2r chain B

Region: 196 - 471
Aligned: 276
Modelled: 276
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: B: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 4;
PDBTitle: crystal structure of pyruvate dehydrogenase kinase isoform 4 in2 complex with adp

Phyre2
3 |
| c2q8fA_ |

### PDB 2q8f chain A

Region: 237 - 474
Aligned: 238
Modelled: 238
Confidence: 100.0%
Identity: 16%
PDB header:transferase
Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 1;
PDBTitle: structure of pyruvate dehydrogenase kinase isoform 1

Phyre2
4 |
| c2c2aA_ |

### PDB 2c2a chain A

Region: 244 - 472
Aligned: 222
Modelled: 229
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:sensor histidine kinase;
PDBTitle: structure of the entire cytoplasmic portion of a sensor2 histidine kinase protein

Phyre2
5 |
| c2bu8A_ |

### PDB 2bu8 chain A

Region: 237 - 474
Aligned: 234
Modelled: 238
Confidence: 100.0%
Identity: 18%
PDB header:transferase
Chain: A: PDB Molecule:pyruvate dehydrogenase kinase isoenzyme 2;
PDBTitle: crystal structures of human pyruvate dehydrogenase kinase 22 containing physiological and synthetic ligands

Phyre2
6 |
| c1y8oA_ |

### PDB 1y8o chain A

Region: 237 - 472
Aligned: 229
Modelled: 236
Confidence: 100.0%
Identity: 18%
PDB header:transferase
Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 3;
PDBTitle: crystal structure of the pdk3-l2 complex

Phyre2
7 |
| c1gjvA_ |

### PDB 1gjv chain A

Region: 214 - 471
Aligned: 252
Modelled: 258
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:[3-methyl-2-oxobutanoate dehydrogenase
PDBTitle: branched-chain alpha-ketoacid dehydrogenase kinase (bck)2 complxed with atp-gamma-s

Phyre2
8 |
| c3a0rA_ |

### PDB 3a0r chain A

Region: 244 - 472
Aligned: 218
Modelled: 229
Confidence: 100.0%
Identity: 20%
PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360)

Phyre2
9 |
| c3a0tA_ |

### PDB 3a0t chain A

Region: 323 - 472
Aligned: 146
Modelled: 150
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: catalytic domain of histidine kinase thka (tm1359) in2 complex with adp and mg ion (trigonal)

Phyre2
10 |
| d2c2aa2 |

### PDB 2c2a chain A domain 2

Region: 322 - 472
Aligned: 144
Modelled: 151
Confidence: 100.0%
Identity: 25%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2
11 |
| d1jm6a2 |

### PDB 1jm6 chain A domain 2

Region: 328 - 472
Aligned: 143
Modelled: 143
Confidence: 100.0%
Identity: 24%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: alpha-ketoacid dehydrogenase kinase, C-terminal domain

Phyre2
12 |
| d1id0a_ |

### PDB 1id0 chain A

Region: 325 - 472
Aligned: 144
Modelled: 146
Confidence: 100.0%
Identity: 25%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2
13 |
| d1gkza2 |

### PDB 1gkz chain A domain 2

Region: 326 - 471
Aligned: 143
Modelled: 146
Confidence: 100.0%
Identity: 20%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: alpha-ketoacid dehydrogenase kinase, C-terminal domain

Phyre2
14 |
| d1bxda_ |

### PDB 1bxd chain A

Region: 319 - 470
Aligned: 148
Modelled: 150
Confidence: 100.0%
Identity: 26%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2
15 |
| c1b3qA_ |

### PDB 1b3q chain A

Region: 264 - 474
Aligned: 204
Modelled: 211
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:protein (chemotaxis protein chea);
PDBTitle: crystal structure of chea-289, a signal transducing histidine kinase

Phyre2
16 |
| c2ch4A_ |

### PDB 2ch4 chain A

Region: 328 - 474
Aligned: 147
Modelled: 147
Confidence: 99.9%
Identity: 22%
PDB header:transferase/chemotaxis
Chain: A: PDB Molecule:chemotaxis protein chea;
PDBTitle: complex between bacterial chemotaxis histidine kinase chea2 domains p4 and p5 and receptor-adaptor protein chew

Phyre2
17 |
| d1ysra1 |

### PDB 1ysr chain A domain 1

Region: 324 - 471
Aligned: 134
Modelled: 148
Confidence: 99.9%
Identity: 30%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2
18 |
| d1i58a_ |

### PDB 1i58 chain A

Region: 328 - 470
Aligned: 143
Modelled: 143
Confidence: 99.9%
Identity: 26%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2
19 |
| c3jz3B_ |

### PDB 3jz3 chain B

Region: 288 - 471
Aligned: 153
Modelled: 157
Confidence: 99.9%
Identity: 25%
PDB header:transferase
Chain: B: PDB Molecule:sensor protein qsec;
PDBTitle: structure of the cytoplasmic segment of histidine kinase qsec

Phyre2
20 |
| d1r62a_ |

### PDB 1r62 chain A

Region: 325 - 470
Aligned: 132
Modelled: 146
Confidence: 99.8%
Identity: 18%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2
21 |
22 |
23 |
24 |
25 |
26 |
27 |
28 |
29 |
30 |
31 |
32 |
33 |
34 |
35 |
36 |
37 |
38 |
39 |
40 |
41 |
42 |
43 |
44 |
45 |
46 |
47 |
48 |
49 |
50 |
51 |
52 |
53 |
54 |
55 |
56 |
57 |
58 |
59 |
60 |
61 |
62 |
63 |
64 |
65 |
66 |
67 |
68 |
69 |
70 |
71 |
72 |
73 |
| d1p0za_ |

### PDB 1p0z chain A

Region: 36 - 173
Aligned: 122
Modelled: 122
Confidence: 95.8%
Identity: 16%
Fold: Profilin-like
Superfamily: Sensory domain-like
Family: Sensory domain of two-component sensor kinase

Phyre2
74 |
75 |
| d3by8a1 |

### PDB 3by8 chain A domain 1

Region: 34 - 178
Aligned: 129
Modelled: 129
Confidence: 94.1%
Identity: 17%
Fold: Profilin-like
Superfamily: Sensory domain-like
Family: Sensory domain of two-component sensor kinase

Phyre2
76 |
77 |
78 |
79 |
80 |
81 |
82 |
83 |
84 |
85 |
86 |
87 |
88 |
89 |
90 |
91 |
92 |
93 |
94 |
95 |
96 |
97 |
98 |
99 |
100 |
101 |
102 |
103 |

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c3d36B_ |
|  | 100.0 | 22 | PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:sporulation kinase b; PDBTitle: how to switch off a histidine kinase: crystal structure of2 geobacillus stearothermophilus kinb with the inhibitor sda
2 | c3d2rB_ |
|  | 100.0 | 17 | PDB header:transferase Chain: B: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 4; PDBTitle: crystal structure of pyruvate dehydrogenase kinase isoform 4 in2 complex with adp
3 | c2q8fA_ |
|  | 100.0 | 16 | PDB header:transferase Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 1; PDBTitle: structure of pyruvate dehydrogenase kinase isoform 1
4 | c2c2aA_ |
|  | 100.0 | 25 | PDB header:transferase Chain: A: PDB Molecule:sensor histidine kinase; PDBTitle: structure of the entire cytoplasmic portion of a sensor2 histidine kinase protein
5 | c2bu8A_ |
|  | 100.0 | 18 | PDB header:transferase Chain: A: PDB Molecule:pyruvate dehydrogenase kinase isoenzyme 2; PDBTitle: crystal structures of human pyruvate dehydrogenase kinase 22 containing physiological and synthetic ligands
6 | c1y8oA_ |
|  | 100.0 | 18 | PDB header:transferase Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 3; PDBTitle: crystal structure of the pdk3-l2 complex
7 | c1gjvA_ |
|  | 100.0 | 17 | PDB header:transferase Chain: A: PDB Molecule:[3-methyl-2-oxobutanoate dehydrogenase PDBTitle: branched-chain alpha-ketoacid dehydrogenase kinase (bck)2 complxed with atp-gamma-s
8 | c3a0rA_ |
|  | 100.0 | 20 | PDB header:transferase Chain: A: PDB Molecule:sensor protein; PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360)
9 | c3a0tA_ |
|  | 100.0 | 25 | PDB header:transferase Chain: A: PDB Molecule:sensor protein; PDBTitle: catalytic domain of histidine kinase thka (tm1359) in2 complex with adp and mg ion (trigonal)
10 | d2c2aa2 |
|  | 100.0 | 25 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase
11 | d1jm6a2 |
|  | 100.0 | 24 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:alpha-ketoacid dehydrogenase kinase, C-terminal domain
12 | d1id0a_ |
|  | 100.0 | 25 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase
13 | d1gkza2 |
|  | 100.0 | 20 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:alpha-ketoacid dehydrogenase kinase, C-terminal domain
14 | d1bxda_ |
|  | 100.0 | 26 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase
15 | c1b3qA_ |
|  | 100.0 | 17 | PDB header:transferase Chain: A: PDB Molecule:protein (chemotaxis protein chea); PDBTitle: crystal structure of chea-289, a signal transducing histidine kinase
16 | c2ch4A_ |
|  | 99.9 | 22 | PDB header:transferase/chemotaxis Chain: A: PDB Molecule:chemotaxis protein chea; PDBTitle: complex between bacterial chemotaxis histidine kinase chea2 domains p4 and p5 and receptor-adaptor protein chew
17 | d1ysra1 |
|  | 99.9 | 30 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase
18 | d1i58a_ |
|  | 99.9 | 26 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase
19 | c3jz3B_ |
|  | 99.9 | 25 | PDB header:transferase Chain: B: PDB Molecule:sensor protein qsec; PDBTitle: structure of the cytoplasmic segment of histidine kinase qsec
20 | d1r62a_ |
|  | 99.8 | 18 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase
21 | c3gieA_ |
| not modelled | 99.8 | 13 | PDB header:transferase Chain: A: PDB Molecule:sensor histidine kinase desk; PDBTitle: crystal structure of deskc_h188e in complex with amp-pcp
22 | d2hkja3 |
| not modelled | 99.8 | 20 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
23 | c3ehgA_ |
| not modelled | 99.7 | 14 | PDB header:transferase Chain: A: PDB Molecule:sensor kinase (yocf protein); PDBTitle: crystal structure of the atp-binding domain of desk in complex with2 atp
24 | c1mx0D_ |
| not modelled | 99.7 | 17 | PDB header:isomerase Chain: D: PDB Molecule:type ii dna topoisomerase vi subunit b; PDBTitle: structure of topoisomerase subunit
25 | c2zbkB_ |
| not modelled | 99.7 | 20 | PDB header:isomerase Chain: B: PDB Molecule:type 2 dna topoisomerase 6 subunit b; PDBTitle: crystal structure of an intact type ii dna topoisomerase:2 insights into dna transfer mechanisms
26 | c3zxqA_ |
| not modelled | 99.7 | 19 | PDB header:transferase Chain: A: PDB Molecule:hypoxia sensor histidine kinase response regulator dost; PDBTitle: crystal structure of the atp-binding domain of mycobacterium2 tuberculosis dost
27 | c2q2eB_ |
| not modelled | 99.7 | 21 | PDB header:isomerase Chain: B: PDB Molecule:type 2 dna topoisomerase 6 subunit b; PDBTitle: crystal structure of the topoisomerase vi holoenzyme from2 methanosarcina mazei
28 | c3zxoB_ |
| not modelled | 99.6 | 19 | PDB header:transferase Chain: B: PDB Molecule:redox sensor histidine kinase response regulator devs; PDBTitle: crystal structure of the mutant atp-binding domain of2 mycobacterium tuberculosis doss
29 | d1h7sa2 |
| not modelled | 99.6 | 15 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
30 | d1ixma_ |
| not modelled | 99.6 | 13 | Fold:Sporulation response regulatory protein Spo0B Superfamily:Sporulation response regulatory protein Spo0B Family:Sporulation response regulatory protein Spo0B
31 | d1th8a_ |
| not modelled | 99.5 | 26 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase
32 | d1bkna2 |
| not modelled | 99.5 | 20 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
33 | d1b63a2 |
| not modelled | 99.4 | 22 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
34 | d1y8oa2 |
| not modelled | 99.4 | 17 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:alpha-ketoacid dehydrogenase kinase, C-terminal domain
35 | c3na3A_ |
| not modelled | 99.0 | 24 | PDB header:protein binding Chain: A: PDB Molecule:dna mismatch repair protein mlh1; PDBTitle: mutl protein homolog 1 isoform 1 from homo sapiens
36 | c3zrwB_ |
| not modelled | 98.7 | 22 | PDB header:signaling protein Chain: B: PDB Molecule:af1503 protein, osmolarity sensor protein envz; PDBTitle: the structure of the dimeric hamp-dhp fusion a291v mutant
37 | c3h4lB_ |
| not modelled | 98.7 | 17 | PDB header:dna binding protein, protein binding Chain: B: PDB Molecule:dna mismatch repair protein pms1; PDBTitle: crystal structure of n terminal domain of a dna repair protein
38 | d1kija2 |
| not modelled | 98.5 | 19 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
39 | d1pvga2 |
| not modelled | 98.4 | 21 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
40 | d1s16a2 |
| not modelled | 98.3 | 17 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
41 | c1bknA_ |
| not modelled | 98.3 | 18 | PDB header:dna repair Chain: A: PDB Molecule:mutl; PDBTitle: crystal structure of an n-terminal 40kd fragment of e. coli2 dna mismatch repair protein mutl
42 | d1ei1a2 |
| not modelled | 98.3 | 22 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
43 | c1ei1B_ |
| not modelled | 98.2 | 22 | PDB header:isomerase Chain: B: PDB Molecule:dna gyrase b; PDBTitle: dimerization of e. coli dna gyrase b provides a structural mechanism2 for activating the atpase catalytic center
44 | c1kijB_ |
| not modelled | 98.2 | 18 | PDB header:isomerase Chain: B: PDB Molecule:dna gyrase subunit b; PDBTitle: crystal structure of the 43k atpase domain of thermus thermophilus2 gyrase b in complex with novobiocin
45 | c1y4sA_ |
| not modelled | 98.2 | 27 | PDB header:chaperone Chain: A: PDB Molecule:chaperone protein htpg; PDBTitle: conformation rearrangement of heat shock protein 90 upon2 adp binding
46 | c1zxnB_ |
| not modelled | 98.1 | 18 | PDB header:isomerase Chain: B: PDB Molecule:dna topoisomerase ii, alpha isozyme; PDBTitle: human dna topoisomerase iia atpase/adp
47 | c3iedA_ |
| not modelled | 98.1 | 21 | PDB header:chaperone Chain: A: PDB Molecule:heat shock protein; PDBTitle: crystal structure of n-terminal domain of plasmodium falciparum hsp902 (pf14_0417) in complex with amppn
48 | c1s16B_ |
| not modelled | 98.1 | 18 | PDB header:isomerase Chain: B: PDB Molecule:topoisomerase iv subunit b; PDBTitle: crystal structure of e. coli topoisomerase iv pare 43kda subunit2 complexed with adpnp
49 | d1uyla_ |
| not modelled | 98.0 | 19 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Heat shock protein 90, HSP90, N-terminal domain
50 | c2cg9A_ |
| not modelled | 98.0 | 24 | PDB header:chaperone Chain: A: PDB Molecule:atp-dependent molecular chaperone hsp82; PDBTitle: crystal structure of an hsp90-sba1 closed chaperone complex
51 | c1ea6A_ |
| not modelled | 98.0 | 23 | PDB header:dna repair Chain: A: PDB Molecule:pms1 protein homolog 2; PDBTitle: n-terminal 40kda fragment of nhpms2 complexed with adp
52 | c2fwyA_ |
| not modelled | 98.0 | 19 | PDB header:chaperone Chain: A: PDB Molecule:heat shock protein hsp 90-alpha; PDBTitle: structure of human hsp90-alpha bound to the potent water2 soluble inhibitor pu-h64
53 | d2iwxa1 |
| not modelled | 98.0 | 21 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Heat shock protein 90, HSP90, N-terminal domain
54 | c1zwhA_ |
| not modelled | 98.0 | 21 | PDB header:chaperone Chain: A: PDB Molecule:atp-dependent molecular chaperone hsp82; PDBTitle: yeast hsp82 in complex with the novel hsp90 inhibitor radester amine
55 | c1qzrA_ |
| not modelled | 97.9 | 20 | PDB header:isomerase Chain: A: PDB Molecule:dna topoisomerase ii; PDBTitle: crystal structure of the atpase region of saccharomyces cerevisiae2 topoisomerase ii bound to icrf-187 (dexrazoxane)
56 | c2iopD_ |
| not modelled | 97.9 | 26 | PDB header:chaperone Chain: D: PDB Molecule:chaperone protein htpg; PDBTitle: crystal structure of full-length htpg, the escherichia coli2 hsp90, bound to adp
57 | c3g7bB_ |
| not modelled | 97.9 | 15 | PDB header:isomerase Chain: B: PDB Molecule:dna gyrase subunit b; PDBTitle: staphylococcus aureus gyrase b co-complex with inhibitor
58 | c2akpA_ |
| not modelled | 97.8 | 20 | PDB header:chaperone Chain: A: PDB Molecule:atp-dependent molecular chaperone hsp82; PDBTitle: hsp90 delta24-n210 mutant
59 | c2o1wB_ |
| not modelled | 97.8 | 26 | PDB header:chaperone Chain: B: PDB Molecule:endoplasmin; PDBTitle: structure of n-terminal plus middle domains (n+m) of grp94
60 | c3pehB_ |
| not modelled | 97.8 | 24 | PDB header:chaperone Chain: B: PDB Molecule:endoplasmin homolog; PDBTitle: crystal structure of the n-terminal domain of an hsp90 from plasmodium2 falciparum, pfl1070c in the presence of a thienopyrimidine derivative
61 | d1s14a_ |
| not modelled | 97.8 | 16 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
62 | d1uyma_ |
| not modelled | 97.7 | 19 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Heat shock protein 90, HSP90, N-terminal domain
63 | c3ke6A_ |
| not modelled | 97.7 | 27 | PDB header:unknown function Chain: A: PDB Molecule:protein rv1364c/mt1410; PDBTitle: the crystal structure of the rsbu and rsbw domains of rv1364c from2 mycobacterium tuberculosis
64 | c3lnrA_ |
| not modelled | 97.7 | 13 | PDB header:signaling protein Chain: A: PDB Molecule:aerotaxis transducer aer2; PDBTitle: crystal structure of poly-hamp domains from the p. aeruginosa soluble2 receptor aer2
65 | c2iorA_ |
| not modelled | 97.7 | 20 | PDB header:chaperone Chain: A: PDB Molecule:chaperone protein htpg; PDBTitle: crystal structure of the n-terminal domain of htpg, the2 escherichia coli hsp90, bound to adp
66 | d2gqpa1 |
| not modelled | 97.5 | 24 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Heat shock protein 90, HSP90, N-terminal domain
67 | d1joya_ |
| not modelled | 97.5 | 21 | Fold:ROP-like Superfamily:Homodimeric domain of signal transducing histidine kinase Family:Homodimeric domain of signal transducing histidine kinase
68 | c3lnuA_ |
| not modelled | 97.5 | 22 | PDB header:isomerase Chain: A: PDB Molecule:topoisomerase iv subunit b; PDBTitle: crystal structure of pare subunit
69 | d2c2aa1 |
| not modelled | 97.5 | 23 | Fold:ROP-like Superfamily:Homodimeric domain of signal transducing histidine kinase Family:Homodimeric domain of signal transducing histidine kinase
70 | d1qy5a_ |
| not modelled | 97.2 | 28 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Heat shock protein 90, HSP90, N-terminal domain
71 | c2o1uA_ |
| not modelled | 97.1 | 34 | PDB header:chaperone Chain: A: PDB Molecule:endoplasmin; PDBTitle: structure of full length grp94 with amp-pnp bound
72 | d2asxa1 |
| not modelled | 96.6 | 24 | Fold:HAMP domain-like Superfamily:HAMP domain-like Family:HAMP domain
73 | d1p0za_ |
|  | 95.8 | 16 | Fold:Profilin-like Superfamily:Sensory domain-like Family:Sensory domain of two-component sensor kinase
74 | c3cwvB_ |
| not modelled | 94.4 | 22 | PDB header:isomerase Chain: B: PDB Molecule:dna gyrase, b subunit, truncated; PDBTitle: crystal structure of b-subunit of the dna gyrase from myxococcus2 xanthus
75 | d3by8a1 |
|  | 94.1 | 17 | Fold:Profilin-like Superfamily:Sensory domain-like Family:Sensory domain of two-component sensor kinase
76 | c3lmmA_ |
| not modelled | 89.3 | 16 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the dip2311 protein from2 corynebacterium diphtheriae, northeast structural genomics3 consortium target cdr35
77 | c2rm8A_ |
| not modelled | 88.2 | 15 | PDB header:signaling protein Chain: A: PDB Molecule:sensory rhodopsin ii transducer; PDBTitle: the solution structure of phototactic transducer protein2 htrii linker region from natronomonas pharaonis
78 | c3fosA_ |
| not modelled | 67.8 | 8 | PDB header:transferase Chain: A: PDB Molecule:sensor protein; PDBTitle: crystal structure of two-component sensor histidine kinase domain from2 bacillus subtilis subsp. subtilis str. 168
79 | d2p7ja2 |
| not modelled | 52.7 | 12 | Fold:Profilin-like Superfamily:Sensory domain-like Family:YkuI C-terminal domain-like
80 | d1g0oa_ |
| not modelled | 49.1 | 19 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
81 | c3by9A_ |
| not modelled | 46.4 | 15 | PDB header:transferase Chain: A: PDB Molecule:sensor protein; PDBTitle: crystal structure of the v. cholerae histidine kinase dctb2 sensor domain
82 | c3e4pB_ |
| not modelled | 43.5 | 10 | PDB header:transferase Chain: B: PDB Molecule:c4-dicarboxylate transport sensor protein dctb; PDBTitle: crystal structure of malonate occupied dctb
83 | c3n0rA_ |
| not modelled | 43.0 | 15 | PDB header:signaling protein Chain: A: PDB Molecule:response regulator; PDBTitle: structure of the phyr stress response regulator at 1.25 angstrom2 resolution
84 | c3o38D_ |
| not modelled | 43.0 | 17 | PDB header:oxidoreductase Chain: D: PDB Molecule:short chain dehydrogenase; PDBTitle: crystal structure of a short chain dehydrogenase from mycobacterium2 smegmatis
85 | c3s8mA_ |
| not modelled | 41.7 | 27 | PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-acp reductase; PDBTitle: the crystal structure of fabv
86 | c3ctmH_ |
| not modelled | 35.1 | 22 | PDB header:oxidoreductase Chain: H: PDB Molecule:carbonyl reductase; PDBTitle: crystal structure of a carbonyl reductase from candida2 parapsilosis with anti-prelog stereo-specificity
87 | c3rd5A_ |
| not modelled | 30.8 | 30 | PDB header:oxidoreductase Chain: A: PDB Molecule:mypaa.01249.c; PDBTitle: crystal structure of a putative uncharacterized protein from2 mycobacterium paratuberculosis
88 | c1ybyB_ |
| not modelled | 30.2 | 17 | PDB header:translation Chain: B: PDB Molecule:translation elongation factor p; PDBTitle: conserved hypothetical protein cth-95 from clostridium2 thermocellum
89 | c3i1jB_ |
| not modelled | 28.4 | 22 | PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase, short chain PDBTitle: structure of a putative short chain dehydrogenase from2 pseudomonas syringae
90 | d1yxma1 |
| not modelled | 26.6 | 22 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
91 | c3pt5A_ |
| not modelled | 26.4 | 9 | PDB header:hydrolase Chain: A: PDB Molecule:nans (yjhs), a 9-o-acetyl n-acetylneuraminic acid esterase; PDBTitle: crystal structure of nans
92 | c3clwF_ |
| not modelled | 25.3 | 12 | PDB header:structural genomics, unknown function Chain: F: PDB Molecule:conserved exported protein; PDBTitle: crystal structure of conserved exported protein from bacteroides2 fragilis
93 | d1efub3 |
| not modelled | 24.6 | 21 | Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:TS-N domain
94 | c3nnhA_ |
| not modelled | 23.0 | 15 | PDB header:rna binding protein/rna Chain: A: PDB Molecule:cugbp elav-like family member 1; PDBTitle: crystal structure of the cugbp1 rrm1 with guuguuuuguuu rna
95 | c1qr0A_ |
| not modelled | 22.8 | 18 | PDB header:transferase Chain: A: PDB Molecule:4'-phosphopantetheinyl transferase sfp; PDBTitle: crystal structure of the 4'-phosphopantetheinyl transferase sfp-2 coenzyme a complex
96 | d1aipc1 |
| not modelled | 22.6 | 16 | Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:TS-N domain
97 | c3gdfA_ |
| not modelled | 22.6 | 17 | PDB header:oxidoreductase Chain: A: PDB Molecule:probable nadp-dependent mannitol dehydrogenase; PDBTitle: crystal structure of the nadp-dependent mannitol dehydrogenase from2 cladosporium herbarum.
98 | d1xb2b1 |
| not modelled | 22.5 | 11 | Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:TS-N domain
99 | c3k31B_ |
| not modelled | 22.2 | 21 | PDB header:oxidoreductase Chain: B: PDB Molecule:enoyl-(acyl-carrier-protein) reductase; PDBTitle: crystal structure of eonyl-(acyl-carrier-protein) reductase from2 anaplasma phagocytophilum in complex with nad at 1.9a resolution
100 | c1vr7A_ |
| not modelled | 22.1 | 17 | PDB header:lyase Chain: A: PDB Molecule:s-adenosylmethionine decarboxylase proenzyme; PDBTitle: crystal structure of s-adenosylmethionine decarboxylase proenzyme2 (tm0655) from thermotoga maritima at 1.2 a resolution
101 | d2cp9a1 |
| not modelled | 21.9 | 11 | Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:TS-N domain
102 | d1vr7a1 |
| not modelled | 21.8 | 16 | Fold:S-adenosylmethionine decarboxylase Superfamily:S-adenosylmethionine decarboxylase Family:Bacterial S-adenosylmethionine decarboxylase
103 | d1w6ua_ |
| not modelled | 20.8 | 11 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0