Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	R	T	M	L	Y	L	S	L	L	A	V	S	C	S	V	S	A	A	K	Y	P	V	L	T	E	S	S	P	E	K	A	G	F	N	V	E	R	L	N	Q	M	D	R	W	I	S	Q	Q	V	D	V	G	Y	P	S	V	N	L
Secondary structure
SS confidence
Disorder		?	?																?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	I	I	K	D	N	Q	I	V	Y	R	K	A	W	G	A	A	K	K	Y	D	G	S	V	L	M	E	Q	P	V	K	A	T	T	G	T	L	Y	D	L	A	S	N	T	K	M	Y	A	T	N	F	A	L	Q	K	L	M	S	E	G
Secondary structure
SS confidence
Disorder																						?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		K	L	H	P	D	D	R	I	A	K	Y	I	P	G	F	A	D	S	P	N	D	T	I	K	G	K	N	T	L	R	I	S	D	L	L	H	H	S	G	G	F	P	A	D	P	Q	Y	P	N	K	A	V	A	G	A	L	Y	S	Q	D
Secondary structure
SS confidence
Disorder																				?	?	?	?	?	?																													?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		K	G	Q	T	L	E	M	I	K	R	T	P	L	E	Y	Q	P	G	S	K	H	I	Y	S	D	V	D	Y	M	L	L	G	F	I	V	E	S	V	T	G	Q	P	L	D	R	Y	V	E	E	S	I	Y	R	P	L	G	L	T	H	T
Secondary structure
SS confidence
Disorder																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		V	F	N	P	L	L	K	G	F	K	P	Q	Q	I	A	A	T	E	L	N	G	N	T	R	D	G	V	I	H	F	P	N	I	R	T	S	T	L	W	G	Q	V	H	D	E	K	A	F	Y	S	M	G	G	V	S	G	H	A	G	L
Secondary structure
SS confidence
Disorder							?	?	?	?		?																						?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		F	S	N	T	G	D	I	A	V	L	M	Q	T	M	L	N	G	G	G	Y	G	D	V	Q	L	F	N	A	E	T	V	K	M	F	T	T	S	S	K	E	D	A	T	F	G	L	G	W	R	V	N	G	N	A	T	M	T	P	T	F
Secondary structure
SS confidence
Disorder																				?			?	?																	?			?										?	?	?	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		G	T	L	A	S	P	Q	T	Y	G	H	T	G	W	T	G	T	V	T	V	I	D	P	V	N	H	M	T	I	V	M	L	S	N	K	P	H	S	P	V	A	D	P	Q	K	N	P	N	M	F	E	S	G	Q	L	P	I	A	T	Y
Secondary structure
SS confidence
Disorder			?	?		?																																	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.
Sequence		G	W	V	V	D	Q	V	Y	A	A	L	K	Q	K
Secondary structure
SS confidence
Disorder													?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3hle chain A Region: 32 - 433 Aligned: 366 Modelled: 402 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:transesterase; PDBTitle: simvastatin synthase (lovd), from aspergillus terreus, s5 mutant, s76a2 mutant, complex with monacolin j acid Phyre2 PDB 1ci9 chain A Region: 36 - 428 Aligned: 366 Modelled: 378 Confidence: 100.0% Identity: 22% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 2qmi chain H Region: 40 - 399 Aligned: 316 Modelled: 338 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: H: PDB Molecule:pbp related beta-lactamase; PDBTitle: structure of the octameric penicillin-binding protein2 homologue from pyrococcus abyssi Phyre2 PDB 2drw chain A domain 1 Region: 37 - 432 Aligned: 351 Modelled: 396 Confidence: 100.0% Identity: 19% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 1rgy chain A Region: 37 - 432 Aligned: 331 Modelled: 339 Confidence: 100.0% Identity: 21% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 2hds chain A domain 1 Region: 37 - 432 Aligned: 331 Modelled: 353 Confidence: 100.0% Identity: 22% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 1onh chain A Region: 35 - 432 Aligned: 336 Modelled: 351 Confidence: 100.0% Identity: 21% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 1ei5 chain A Region: 40 - 417 Aligned: 325 Modelled: 350 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:d-aminopeptidase; PDBTitle: crystal structure of a d-aminopeptidase from ochrobactrum2 anthropi Phyre2 PDB 3ozh chain A Region: 41 - 432 Aligned: 333 Modelled: 343 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase/d-alanine carboxypeptidase; PDBTitle: crystal structure of beta-lactamase/d-alanine carboxypeptidase from2 yersinia pestis Phyre2 PDB 2wzz chain A Region: 37 - 432 Aligned: 332 Modelled: 340 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: amp-c beta-lactamase (pseudomonas aeruginosa)in complex2 with compound m-03 Phyre2 PDB 1yqs chain A domain 1 Region: 40 - 434 Aligned: 332 Modelled: 340 Confidence: 100.0% Identity: 19% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 3tg9 chain A Region: 43 - 398 Aligned: 306 Modelled: 330 Confidence: 100.0% Identity: 19% PDB header:penicillin binding protein Chain: A: PDB Molecule:penicillin-binding protein; PDBTitle: the crystal structure of penicillin binding protein from bacillus2 halodurans Phyre2 PDB 1zkj chain A Region: 41 - 431 Aligned: 325 Modelled: 342 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:extended-spectrum beta-lactamase; PDBTitle: structural basis for the extended substrate spectrum of cmy-2 10, a plasmid-encoded class c beta-lactamase Phyre2 PDB 2qz6 chain A Region: 38 - 431 Aligned: 319 Modelled: 339 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: first crystal structure of a psychrophile class c beta-2 lactamase Phyre2 PDB 3o3v chain B Region: 41 - 432 Aligned: 317 Modelled: 352 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of clbp peptidase domain Phyre2 PDB 2dcf chain A domain 1 Region: 16 - 432 Aligned: 323 Modelled: 354 Confidence: 100.0% Identity: 19% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 1ei5 chain A domain 3 Region: 41 - 412 Aligned: 319 Modelled: 343 Confidence: 100.0% Identity: 18% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 3i7j chain B Region: 47 - 431 Aligned: 261 Modelled: 263 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase mb2281c; PDBTitle: crystal structure of a beta-lactamase (mb2281c) from2 mycobacterium bovis, northeast structural genomics3 consortium target mbr246 Phyre2 PDB 1tvf chain A domain 2 Region: 56 - 429 Aligned: 256 Modelled: 275 Confidence: 99.5% Identity: 16% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 1tvf chain A Region: 56 - 434 Aligned: 262 Modelled: 281 Confidence: 99.5% Identity: 16% PDB header:penicillin binding Chain: A: PDB Molecule:penicillin binding protein 4; PDBTitle: crystal structure of penicillin-binding protein 4 (pbp4)2 from staphylococcus aureus Phyre2 1 c3hleA_ 2 d1ci9a_ 3 c2qmiH_ 4 d2drwa1 5 d1rgya_ 6 d2hdsa1 7 d1onha_ 8 c1ei5A_ 9 c3ozhA_ 10 c2wzzA_ 11 d1yqsa1 12 c3tg9A_ 13 c1zkjA_ 14 c2qz6A_ 15 c3o3vB_ 16 d2dcfa1 17 d1ei5a3 18 c3i7jB_ 19 d1tvfa2 20 c1tvfA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3hleA_ 100.0 19 PDB header:transferase Chain: A: PDB Molecule:transesterase; PDBTitle: simvastatin synthase (lovd), from aspergillus terreus, s5 mutant, s76a2 mutant, complex with monacolin j acid 2 d1ci9a_ 100.0 22 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 3 c2qmiH_ 100.0 24 PDB header:hydrolase Chain: H: PDB Molecule:pbp related beta-lactamase; PDBTitle: structure of the octameric penicillin-binding protein2 homologue from pyrococcus abyssi 4 d2drwa1 100.0 19 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 5 d1rgya_ 100.0 21 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 6 d2hdsa1 100.0 22 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 7 d1onha_ 100.0 21 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 8 c1ei5A_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:d-aminopeptidase; PDBTitle: crystal structure of a d-aminopeptidase from ochrobactrum2 anthropi 9 c3ozhA_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase/d-alanine carboxypeptidase; PDBTitle: crystal structure of beta-lactamase/d-alanine carboxypeptidase from2 yersinia pestis 10 c2wzzA_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: amp-c beta-lactamase (pseudomonas aeruginosa)in complex2 with compound m-03 11 d1yqsa1 100.0 19 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 12 c3tg9A_ 100.0 19 PDB header:penicillin binding protein Chain: A: PDB Molecule:penicillin-binding protein; PDBTitle: the crystal structure of penicillin binding protein from bacillus2 halodurans 13 c1zkjA_ 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:extended-spectrum beta-lactamase; PDBTitle: structural basis for the extended substrate spectrum of cmy-2 10, a plasmid-encoded class c beta-lactamase 14 c2qz6A_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: first crystal structure of a psychrophile class c beta-2 lactamase 15 c3o3vB_ 100.0 22 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of clbp peptidase domain 16 d2dcfa1 100.0 19 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 17 d1ei5a3 100.0 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 18 c3i7jB_ 100.0 26 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase mb2281c; PDBTitle: crystal structure of a beta-lactamase (mb2281c) from2 mycobacterium bovis, northeast structural genomics3 consortium target mbr246 19 d1tvfa2 99.5 16 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 20 c1tvfA_ 99.5 16 PDB header:penicillin binding Chain: A: PDB Molecule:penicillin binding protein 4; PDBTitle: crystal structure of penicillin-binding protein 4 (pbp4)2 from staphylococcus aureus 21 c3humB_ not modelled 99.4 16 PDB header:hydrolase/antibiotics Chain: B: PDB Molecule:penicillin-binding protein 4; PDBTitle: crystal structure of penicillin binding protein 4 from2 staphylococcus aureus col in complex with cefotaxime 22 d1buea_ not modelled 99.4 20 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 23 c2wuqB_ not modelled 99.3 14 PDB header:transcription Chain: B: PDB Molecule:beta-lactamase regulatory protein blab; PDBTitle: crystal structure of blab protein from streptomyces cacaoi 24 d1m40a_ not modelled 99.3 14 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 25 c2wuqA_ not modelled 99.3 15 PDB header:transcription Chain: A: PDB Molecule:beta-lactamase regulatory protein blab; PDBTitle: crystal structure of blab protein from streptomyces cacaoi 26 d1hzoa_ not modelled 99.3 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 27 c2qpnA_ not modelled 99.2 12 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase ges-1; PDBTitle: ges-1 beta-lactamase 28 c2ov5A_ not modelled 99.2 19 PDB header:hydrolase Chain: A: PDB Molecule:carbapenemase; PDBTitle: crystal structure of the kpc-2 carbapenemase 29 c2j7vA_ not modelled 99.2 19 PDB header:hydrolase Chain: A: PDB Molecule:tll2115 protein; PDBTitle: structure of pbp-a 30 d1e25a_ not modelled 99.2 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 31 d1g6aa_ not modelled 99.2 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 32 d1i2sa_ not modelled 99.2 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 33 c1i2sA_ not modelled 99.2 17 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: beta-lactamase from bacillus licheniformis bs3 34 d1bsga_ not modelled 99.2 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 35 c3it9B_ not modelled 99.1 27 PDB header:hydrolase Chain: B: PDB Molecule:d-alanyl-d-alanine carboxypeptidase dacc; PDBTitle: crystal structure of penicillin-binding protein 6 (pbp6)2 from e. coli in apo state 36 d1n9ba_ not modelled 99.1 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 37 d1xp4a2 not modelled 99.1 13 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 38 c1z6fA_ not modelled 99.1 24 PDB header:hydrolase Chain: A: PDB Molecule:penicillin-binding protein 5; PDBTitle: crystal structure of penicillin-binding protein 5 from e. coli in2 complex with a boronic acid inhibitor 39 d1dy6a_ not modelled 99.1 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 40 c3p09A_ not modelled 99.1 18 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of beta-lactamase from francisella tularensis 41 c3a3jA_ not modelled 99.1 22 PDB header:hydrolase Chain: A: PDB Molecule:pbp5; PDBTitle: crystal structures of penicillin binding protein 5 from2 haemophilus influenzae 42 d1iysa_ not modelled 99.1 16 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 43 c3p09B_ not modelled 99.1 19 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of beta-lactamase from francisella tularensis 44 c1xp4C_ not modelled 99.1 12 PDB header:hydrolase Chain: C: PDB Molecule:d-alanyl-d-alanine carboxypeptidase; PDBTitle: crystal structure of a peptidoglycan synthesis regulatory2 factor (pbp3) from streptococcus pneumoniae 45 d3beca2 not modelled 99.0 25 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 46 d2cc1a1 not modelled 99.0 19 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 47 c3dw0B_ not modelled 99.0 20 PDB header:hydrolase Chain: B: PDB Molecule:class a carbapenemase kpc-2; PDBTitle: crystal structure of the class a carbapenemase kpc-2 at 1.62 angstrom resolution 48 c3qhyA_ not modelled 99.0 18 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:beta-lactamase; PDBTitle: structural, thermodynamic and kinetic analysis of the picomolar2 binding affinity interaction of the beta-lactamase inhibitor protein-3 ii (blip-ii) with class a beta-lactamases 49 c2v20A_ not modelled 99.0 13 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase tem; PDBTitle: structure of a tem-1 beta-lactamase insertant2 allosterically regulated by kanamycin and anions. complex3 with sulfate. 50 c1w7fB_ not modelled 98.9 17 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of the class a beta-lactamase bs32 inhibited with isocitrate 51 c3lezA_ not modelled 98.9 13 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of a halotolerant bacterial beta-lactamase 52 c3cjmA_ not modelled 98.9 10 PDB header:hydrolase Chain: A: PDB Molecule:putative beta-lactamase; PDBTitle: crystal structure of putative beta-lactamase (np_815223.1) from2 enterococcus faecalis v583 at 1.50 a resolution 53 c3cg5A_ not modelled 98.9 14 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of the covalent adduct formed between tb2 b-lactamase and clavulanate 54 d1o7ea_ not modelled 98.8 14 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 55 d1es5a_ not modelled 98.7 22 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 56 d1alqa_ not modelled 98.5 19 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 57 d1djaa_ not modelled 98.5 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 58 c2bcfA_ not modelled 98.4 15 PDB header:hydrolase Chain: A: PDB Molecule:probable d-alanyl-d-alanine carboxypeptidase PDBTitle: crystal structure of a evolved putative penicillin-binding2 protein homolog, rv2911, from mycobacterium tuberculosis. 59 c2xftA_ not modelled 98.3 12 PDB header:hydrolase Chain: A: PDB Molecule:orf12; PDBTitle: structural and mechanistic studies on a cephalosporin esterase from2 the clavulanic acid biosynthesis pathway 60 c3mfdB_ not modelled 98.2 23 PDB header:hydrolase Chain: B: PDB Molecule:d-alanyl-d-alanine carboxypeptidase dacb; PDBTitle: the structure of the beta-lactamase superfamily domain of d-alanyl-d-2 alanine carboxypeptidase from bacillus subtilis 61 c3pbqA_ not modelled 97.4 17 PDB header:hydrolase/antibiotic Chain: A: PDB Molecule:penicillin-binding protein 3; PDBTitle: crystal structure of pbp3 complexed with imipenem 62 d1rp5a4 not modelled 97.3 14 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 63 c3oc2A_ not modelled 97.1 18 PDB header:penicillin-binding protein Chain: A: PDB Molecule:penicillin-binding protein 3; PDBTitle: crystal structure of penicillin-binding protein 3 from pseudomonas2 aeruginosa 64 d1pyya4 not modelled 97.0 14 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 65 c3ih9A_ not modelled 96.4 15 PDB header:hydrolase Chain: A: PDB Molecule:salt-tolerant glutaminase; PDBTitle: crystal structure analysis of mglu in its tris form 66 c3ue3A_ not modelled 96.4 15 PDB header:transferase Chain: A: PDB Molecule:septum formation, penicillin binding protein 3, PDBTitle: crystal structure of acinetobacter baumanni pbp3 67 c2dfwA_ not modelled 96.2 15 PDB header:hydrolase Chain: A: PDB Molecule:salt-tolerant glutaminase; PDBTitle: crystal structure of a major fragment of the salt-tolerant2 glutaminase from micrococcus luteus k-3 68 c2jc7A_ not modelled 95.9 19 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase oxa-24; PDBTitle: the crystal structure of the carbapenemase oxa-24 reveals2 new insights into the mechanism of carbapenem-hydrolysis 69 d1u60a_ not modelled 95.6 20 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Glutaminase 70 c3equB_ not modelled 95.2 12 PDB header:biosynthetic protein Chain: B: PDB Molecule:penicillin-binding protein 2; PDBTitle: crystal structure of penicillin-binding protein 2 from neisseria2 gonorrhoeae 71 c2wadB_ not modelled 94.8 11 PDB header:peptide binding protein Chain: B: PDB Molecule:penicillin-binding protein 2b; PDBTitle: penicillin-binding protein 2b (pbp-2b) from streptococcus2 pneumoniae (strain 5204) 72 c1qmfA_ not modelled 94.7 12 PDB header:peptidoglycan synthesis Chain: A: PDB Molecule:penicillin-binding protein 2x; PDBTitle: penicillin-binding protein 2x (pbp-2x) acyl-enzyme complex 73 d1w5da1 not modelled 94.2 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 74 d1nrfa_ not modelled 93.6 11 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 75 c2jciA_ not modelled 93.4 16 PDB header:drug-binding protein Chain: A: PDB Molecule:penicillin-binding protein 1b; PDBTitle: structural insights into the catalytic mechanism and the2 role of streptococcus pneumoniae pbp1b 76 d1w79a1 not modelled 93.4 20 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 77 c3dwkC_ not modelled 93.3 14 PDB header:transferase Chain: C: PDB Molecule:penicillin-binding protein 2; PDBTitle: identification of dynamic structural motifs involved in2 peptidoglycan glycosyltransfer 78 c2bg1A_ not modelled 93.1 17 PDB header:peptidoglycan Chain: A: PDB Molecule:penicillin-binding protein 1b; PDBTitle: active site restructuring regulates ligand recognition in2 classa penicillin-binding proteins (pbps) 79 c3a3eB_ not modelled 92.6 22 PDB header:hydrolase Chain: B: PDB Molecule:penicillin-binding protein 4; PDBTitle: crystal structure of penicillin binding protein 4 (dacb)2 from haemophilus influenzae, complexed with novel beta-3 lactam (cmv) 80 c3lo7A_ not modelled 92.6 16 PDB header:transferase Chain: A: PDB Molecule:penicillin-binding protein a; PDBTitle: crystal structure of pbpa from mycobacterium tuberculosis 81 c3fwlA_ not modelled 92.2 15 PDB header:transferase, hydrolase Chain: A: PDB Molecule:penicillin-binding protein 1b; PDBTitle: crystal structure of the full-length transglycosylase pbp1b2 from escherichia coli 82 d2bg1a1 not modelled 92.0 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 83 d1k25a4 not modelled 91.4 14 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 84 c1pmdA_ not modelled 91.3 12 PDB header:peptidoglycan synthesis Chain: A: PDB Molecule:peptidoglycan synthesis multifunctional enzyme; PDBTitle: penicillin-binding protein 2x (pbp-2x) 85 d2ex2a1 not modelled 91.2 19 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 86 d2olua2 not modelled 89.6 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 87 d1mkia_ not modelled 89.6 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Glutaminase 88 d2c5wb1 not modelled 88.8 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 89 d1xa1a_ not modelled 88.2 9 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 90 d1vqqa3 not modelled 86.2 10 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 91 c3czdA_ not modelled 85.1 20 PDB header:hydrolase Chain: A: PDB Molecule:glutaminase kidney isoform; PDBTitle: crystal structure of human glutaminase in complex with l-glutamate 92 c3uo9B_ not modelled 84.0 18 PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:glutaminase kidney isoform, mitochondrial; PDBTitle: crystal structure of human gac in complex with glutamate and bptes 93 c3ss4C_ not modelled 83.9 18 PDB header:hydrolase Chain: C: PDB Molecule:glutaminase c; PDBTitle: crystal structure of mouse glutaminase c, phosphate-bound form 94 c2pbyB_ not modelled 80.8 14 PDB header:hydrolase Chain: B: PDB Molecule:glutaminase; PDBTitle: probable glutaminase from geobacillus kaustophilus hta426 95 c2olvA_ not modelled 79.5 13 PDB header:transferase Chain: A: PDB Molecule:penicillin-binding protein 2; PDBTitle: structural insight into the transglycosylation step of bacterial cell2 wall biosynthesis : donor ligand complex 96 d1m6ka_ not modelled 75.6 11 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 97 c3udiA_ not modelled 71.4 28 PDB header:penicillin-binding protein/antibiotic Chain: A: PDB Molecule:penicillin-binding protein 1a; PDBTitle: crystal structure of acinetobacter baumannii pbp1a in complex with2 penicillin g 98 c2iwdA_ not modelled 68.7 9 PDB header:antibiotic resistance Chain: A: PDB Molecule:methicillin resistance mecr1 protein; PDBTitle: oxacilloyl-acylated mecr1 extracellular antibiotic-sensor2 domain. 99 c3if6C_ not modelled 62.4 13 PDB header:hydrolase Chain: C: PDB Molecule:oxa-46 oxacillinase; PDBTitle: crystal structure of oxa-46 beta-lactamase from p.2 aeruginosa 100 c1mwuA_ not modelled 51.1 10 PDB header:biosynthetic protein Chain: A: PDB Molecule:penicillin-binding protein 2a; PDBTitle: structure of methicillin acyl-penicillin binding protein 2a2 from methicillin resistant staphylococcus aureus strain3 27r at 2.60 a resolution. 101 c3hbrD_ not modelled 33.6 14 PDB header:hydrolase Chain: D: PDB Molecule:oxa-48; PDBTitle: crystal structure of oxa-48 beta-lactamase 102 d1k55a_ not modelled 33.5 20 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0