Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP27550
DateThu Jan 5 11:44:02 GMT 2012
Unique Job ID0594b43bd8485a50

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1pg4a_
Top template information
Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
Confidence and coverage
Confidence:100.0% Coverage: 97%
633 residues ( 97% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSQIHKHTIPANIADRCLINPQQYEAMYQQSINVPDTFWGEQGKILDWIKPYQKVKNTSF
Secondary structure 
SS confidence 
Disorder  ???????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  APGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDASQSKHISYKELHRDVCRF
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  ANTLLELGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSNS
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  RLVITSDEGVRAGRSIPLKKNVDDALKNPNVTSVEHVVVLKRTGGKIDWQEGRDLWWHDL
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  VEQASDQHQAEEMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAALTFKYVFDYHPGDI
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  YWCTADVGWVTGHSYLLYGPLACGATTLMFEGVPNWPTPARMAQVVDKHQVNILYTAPTA
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  IRALMAEGDKAIEGTDRSSLRILGSVGEPINPEAWEWYWKKIGNEKCPVVDTWWQTETGG
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  FMITPLPGATELKAGSATRPFFGVQPALVDNEGNPLEGATEGSLVITDSWPGQARTLFGD
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  HERFEQTYFSTFKNMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHP
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  KIAEAAVVGIPHNIKGQAIYAYVTLNHGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTD
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 
   .........610.........620.........630.........640.........650..
Sequence  SLPKTRSGKIMRRILRKIAAGDTSNLGDTSTLADPGVVEKLLEEKQAIAMPS
Secondary structure 
SS confidence 
Disorder 
????????
??????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1pg4 chain A

3D model

Region: 5 - 647
Aligned: 633
Modelled: 643
Confidence: 100.0%
Identity: 95%
Fold: Acetyl-CoA synthetase-like
Superfamily: Acetyl-CoA synthetase-like
Family: Acetyl-CoA synthetase-like

Phyre2

PDB 1ry2 chain A

3D model

Region: 22 - 646
Aligned: 606
Modelled: 612
Confidence: 100.0%
Identity: 47%
Fold: Acetyl-CoA synthetase-like
Superfamily: Acetyl-CoA synthetase-like
Family: Acetyl-CoA synthetase-like

Phyre2

PDB 2vsq chain A

3D model

Region: 14 - 645
Aligned: 568
Modelled: 589
Confidence: 100.0%
Identity: 19%
PDB header:ligase
Chain: A: PDB Molecule:surfactin synthetase subunit 3;
PDBTitle: structure of surfactin a synthetase c (srfa-c), a2 nonribosomal peptide synthetase termination module

Phyre2

PDB 3etc chain B

3D model

Region: 67 - 604
Aligned: 513
Modelled: 535
Confidence: 100.0%
Identity: 26%
PDB header:ligase
Chain: B: PDB Molecule:amp-binding protein;
PDBTitle: 2.1 a structure of acyl-adenylate synthetase from methanosarcina2 acetivorans containing a link between lys256 and cys298

Phyre2

PDB 3e7w chain A

3D model

Region: 77 - 620
Aligned: 496
Modelled: 509
Confidence: 100.0%
Identity: 19%
PDB header:ligase
Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1;
PDBTitle: crystal structure of dlta: implications for the reaction2 mechanism of non-ribosomal peptide synthetase (nrps)3 adenylation domains

Phyre2

PDB 3cw9 chain A domain 1

3D model

Region: 76 - 620
Aligned: 500
Modelled: 520
Confidence: 100.0%
Identity: 21%
Fold: Acetyl-CoA synthetase-like
Superfamily: Acetyl-CoA synthetase-like
Family: Acetyl-CoA synthetase-like

Phyre2

PDB 3tsy chain A

3D model

Region: 77 - 612
Aligned: 498
Modelled: 536
Confidence: 100.0%
Identity: 19%
PDB header:ligase, transferase
Chain: A: PDB Molecule:fusion protein 4-coumarate--coa ligase 1, resveratrol
PDBTitle: 4-coumaroyl-coa ligase::stilbene synthase fusion protein

Phyre2

PDB 1mdb chain A

3D model

Region: 46 - 620
Aligned: 528
Modelled: 556
Confidence: 100.0%
Identity: 20%
Fold: Acetyl-CoA synthetase-like
Superfamily: Acetyl-CoA synthetase-like
Family: Acetyl-CoA synthetase-like

Phyre2

PDB 3eyn chain B

3D model

Region: 68 - 619
Aligned: 517
Modelled: 532
Confidence: 100.0%
Identity: 24%
PDB header:ligase
Chain: B: PDB Molecule:acyl-coenzyme a synthetase acsm2a;
PDBTitle: crystal structure of human acyl-coa synthetase medium-chain2 family member 2a (l64p mutation) in a complex with coa

Phyre2

PDB 3ni2 chain A

3D model

Region: 77 - 617
Aligned: 502
Modelled: 514
Confidence: 100.0%
Identity: 22%
PDB header:ligase
Chain: A: PDB Molecule:4-coumarate:coa ligase;
PDBTitle: crystal structures and enzymatic mechanisms of a populus tomentosa 4-2 coumarate:coa ligase

Phyre2

PDB 3gqw chain B

3D model

Region: 73 - 619
Aligned: 504
Modelled: 518
Confidence: 100.0%
Identity: 18%
PDB header:ligase
Chain: B: PDB Molecule:fatty acid amp ligase;
PDBTitle: crystal structure of a fatty acid amp ligase from e. coli with an acyl2 adenylate product bound

Phyre2

PDB 3kxw chain A

3D model

Region: 77 - 627
Aligned: 516
Modelled: 521
Confidence: 100.0%
Identity: 17%
PDB header:ligase
Chain: A: PDB Molecule:saframycin mx1 synthetase b;
PDBTitle: the crystal structure of fatty acid amp ligase from legionella2 pneumophila

Phyre2

PDB 3ite chain B

3D model

Region: 79 - 616
Aligned: 486
Modelled: 504
Confidence: 100.0%
Identity: 15%
PDB header:ligase
Chain: B: PDB Molecule:sidn siderophore synthetase;
PDBTitle: the third adenylation domain of the fungal sidn non-2 ribosomal peptide synthetase

Phyre2

PDB 2v7b chain B

3D model

Region: 77 - 617
Aligned: 487
Modelled: 510
Confidence: 100.0%
Identity: 26%
PDB header:ligase
Chain: B: PDB Molecule:benzoate-coenzyme a ligase;
PDBTitle: crystal structures of a benzoate coa ligase from2 burkholderia xenovorans lb400

Phyre2

PDB 2d1t chain A

3D model

Region: 76 - 622
Aligned: 515
Modelled: 544
Confidence: 100.0%
Identity: 19%
PDB header:oxidoreductase
Chain: A: PDB Molecule:luciferin 4-monooxygenase;
PDBTitle: crystal structure of the thermostable japanese firefly2 luciferase red-color emission s286n mutant complexed with3 high-energy intermediate analogue

Phyre2

PDB 1amu chain A

3D model

Region: 77 - 617
Aligned: 476
Modelled: 503
Confidence: 100.0%
Identity: 22%
Fold: Acetyl-CoA synthetase-like
Superfamily: Acetyl-CoA synthetase-like
Family: Acetyl-CoA synthetase-like

Phyre2

PDB 3dhv chain A

3D model

Region: 78 - 621
Aligned: 493
Modelled: 511
Confidence: 100.0%
Identity: 17%
PDB header:ligase
Chain: A: PDB Molecule:d-alanine-poly(phosphoribitol) ligase;
PDBTitle: crystal structure of dlta protein in complex with d-alanine2 adenylate

Phyre2

PDB 1amu chain B

3D model

Region: 76 - 617
Aligned: 476
Modelled: 505
Confidence: 100.0%
Identity: 21%
PDB header:peptide synthetase
Chain: B: PDB Molecule:gramicidin synthetase 1;
PDBTitle: phenylalanine activating domain of gramicidin synthetase 12 in a complex with amp and phenylalanine

Phyre2

PDB 3l8c chain A

3D model

Region: 74 - 620
Aligned: 491
Modelled: 510
Confidence: 100.0%
Identity: 16%
PDB header:ligase
Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1;
PDBTitle: structure of probable d-alanine--poly(phosphoribitol) ligase2 subunit-1 from streptococcus pyogenes

Phyre2

PDB 1lci chain A

3D model

Region: 76 - 617
Aligned: 501
Modelled: 528
Confidence: 100.0%
Identity: 18%
Fold: Acetyl-CoA synthetase-like
Superfamily: Acetyl-CoA synthetase-like
Family: Acetyl-CoA synthetase-like

Phyre2
1
d1pg4a_
2
d1ry2a_
3
c2vsqA_
4
c3etcB_
5
c3e7wA_
6
d3cw9a1
7
c3tsyA_
8
d1mdba_
9
c3eynB_
10
c3ni2A_
11
c3gqwB_
12
c3kxwA_
13
c3iteB_
14
c2v7bB_
15
c2d1tA_
16
d1amua_
17
c3dhvA_
18
c1amuB_
19
c3l8cA_
20
d1lcia_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
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61
62
63
64
65
66
67
68
69
70
71
72
73
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75
76
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81
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99



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1pg4a_
100.0 95 Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
2d1ry2a_
100.0 47 Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
3c2vsqA_
100.0 19 PDB header:ligase
Chain: A: PDB Molecule:surfactin synthetase subunit 3;
PDBTitle: structure of surfactin a synthetase c (srfa-c), a2 nonribosomal peptide synthetase termination module
4c3etcB_
100.0 26 PDB header:ligase
Chain: B: PDB Molecule:amp-binding protein;
PDBTitle: 2.1 a structure of acyl-adenylate synthetase from methanosarcina2 acetivorans containing a link between lys256 and cys298
5c3e7wA_
100.0 19 PDB header:ligase
Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1;
PDBTitle: crystal structure of dlta: implications for the reaction2 mechanism of non-ribosomal peptide synthetase (nrps)3 adenylation domains
6d3cw9a1
100.0 21 Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
7c3tsyA_
100.0 19 PDB header:ligase, transferase
Chain: A: PDB Molecule:fusion protein 4-coumarate--coa ligase 1, resveratrol
PDBTitle: 4-coumaroyl-coa ligase::stilbene synthase fusion protein
8d1mdba_
100.0 20 Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
9c3eynB_
100.0 24 PDB header:ligase
Chain: B: PDB Molecule:acyl-coenzyme a synthetase acsm2a;
PDBTitle: crystal structure of human acyl-coa synthetase medium-chain2 family member 2a (l64p mutation) in a complex with coa
10c3ni2A_
100.0 22 PDB header:ligase
Chain: A: PDB Molecule:4-coumarate:coa ligase;
PDBTitle: crystal structures and enzymatic mechanisms of a populus tomentosa 4-2 coumarate:coa ligase
11c3gqwB_
100.0 18 PDB header:ligase
Chain: B: PDB Molecule:fatty acid amp ligase;
PDBTitle: crystal structure of a fatty acid amp ligase from e. coli with an acyl2 adenylate product bound
12c3kxwA_
100.0 17 PDB header:ligase
Chain: A: PDB Molecule:saframycin mx1 synthetase b;
PDBTitle: the crystal structure of fatty acid amp ligase from legionella2 pneumophila
13c3iteB_
100.0 15 PDB header:ligase
Chain: B: PDB Molecule:sidn siderophore synthetase;
PDBTitle: the third adenylation domain of the fungal sidn non-2 ribosomal peptide synthetase
14c2v7bB_
100.0 26 PDB header:ligase
Chain: B: PDB Molecule:benzoate-coenzyme a ligase;
PDBTitle: crystal structures of a benzoate coa ligase from2 burkholderia xenovorans lb400
15c2d1tA_
100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:luciferin 4-monooxygenase;
PDBTitle: crystal structure of the thermostable japanese firefly2 luciferase red-color emission s286n mutant complexed with3 high-energy intermediate analogue
16d1amua_
100.0 22 Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
17c3dhvA_
100.0 17 PDB header:ligase
Chain: A: PDB Molecule:d-alanine-poly(phosphoribitol) ligase;
PDBTitle: crystal structure of dlta protein in complex with d-alanine2 adenylate
18c1amuB_
100.0 21 PDB header:peptide synthetase
Chain: B: PDB Molecule:gramicidin synthetase 1;
PDBTitle: phenylalanine activating domain of gramicidin synthetase 12 in a complex with amp and phenylalanine
19c3l8cA_
100.0 16 PDB header:ligase
Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1;
PDBTitle: structure of probable d-alanine--poly(phosphoribitol) ligase2 subunit-1 from streptococcus pyogenes
20d1lcia_
100.0 18 Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
21d1v25a_
not modelled 100.0 20 Fold:Acetyl-CoA synthetase-like
Superfamily:Acetyl-CoA synthetase-like
Family:Acetyl-CoA synthetase-like
22c3nyrA_
not modelled 100.0 23 PDB header:ligase
Chain: A: PDB Molecule:malonyl-coa ligase;
PDBTitle: malonyl-coa ligase ternary product complex with malonyl-coa and amp2 bound
23c3iplB_
not modelled 100.0 20 PDB header:ligase
Chain: B: PDB Molecule:2-succinylbenzoate--coa ligase;
PDBTitle: crystal structure of o-succinylbenzoic acid-coa ligase from2 staphylococcus aureus subsp. aureus mu50
24c3g7sA_
not modelled 100.0 18 PDB header:ligase
Chain: A: PDB Molecule:long-chain-fatty-acid--coa ligase (fadd-1);
PDBTitle: crystal structure of a long-chain-fatty-acid-coa ligase2 (fadd1) from archaeoglobus fulgidus
25c3o82B_
not modelled 100.0 19 PDB header:ligase
Chain: B: PDB Molecule:peptide arylation enzyme;
PDBTitle: structure of base n-terminal domain from acinetobacter baumannii bound2 to 5'-o-[n-(2,3-dihydroxybenzoyl)sulfamoyl] adenosine
26c3o82A_
not modelled 100.0 20 PDB header:ligase
Chain: A: PDB Molecule:peptide arylation enzyme;
PDBTitle: structure of base n-terminal domain from acinetobacter baumannii bound2 to 5'-o-[n-(2,3-dihydroxybenzoyl)sulfamoyl] adenosine
27c3ivrA_
not modelled 100.0 20 PDB header:ligase
Chain: A: PDB Molecule:putative long-chain-fatty-acid coa ligase;
PDBTitle: crystal structure of putative long-chain-fatty-acid coa ligase from2 rhodopseudomonas palustris cga009
28c3e53A_
not modelled 100.0 18 PDB header:ligase
Chain: A: PDB Molecule:fatty-acid-coa ligase fadd28;
PDBTitle: crystal structure of n-terminal domain of a fatty acyl amp2 ligase faal28 from mycobacterium tuberculosis
29c2y4oA_
not modelled 100.0 20 PDB header:ligase
Chain: A: PDB Molecule:phenylacetate-coenzyme a ligase;
PDBTitle: crystal structure of paak2 in complex with phenylacetyl adenylate
30c2y27B_
not modelled 100.0 20 PDB header:ligase
Chain: B: PDB Molecule:phenylacetate-coenzyme a ligase;
PDBTitle: crystal structure of paak1 in complex with atp from2 burkholderia cenocepacia
31c3qovD_
not modelled 100.0 15 PDB header:ligase
Chain: D: PDB Molecule:phenylacetate-coenzyme a ligase;
PDBTitle: crystal structure of a hypothetical acyl-coa ligase (bt_0428) from2 bacteroides thetaiotaomicron vpi-5482 at 2.20 a resolution
32c3hguB_
not modelled 100.0 13 PDB header:biosynthetic protein
Chain: B: PDB Molecule:ehpf;
PDBTitle: structure of phenazine antibiotic biosynthesis protein
33c3laxA_
not modelled 99.6 12 PDB header:ligase
Chain: A: PDB Molecule:phenylacetate-coenzyme a ligase;
PDBTitle: the crystal structure of a domain of phenylacetate-coenzyme2 a ligase from bacteroides vulgatus atcc 8482
34d2ayia1
not modelled 74.5 19 Fold:Thermophilic metalloprotease-like
Superfamily:Thermophilic metalloprotease-like
Family:Thermophilic metalloprotease (M29)
35c3smaD_
not modelled 58.1 21 PDB header:transferase
Chain: D: PDB Molecule:frbf;
PDBTitle: a new n-acetyltransferase fold in the structure and mechanism of the2 phosphonate biosynthetic enzyme frbf
36d2nyga1
not modelled 51.7 21 Fold:TTHA0583/YokD-like
Superfamily:TTHA0583/YokD-like
Family:Aminoglycoside 3-N-acetyltransferase-like
37c3e4fB_
not modelled 48.2 21 PDB header:transferase
Chain: B: PDB Molecule:aminoglycoside n3-acetyltransferase;
PDBTitle: crystal structure of ba2930- a putative aminoglycoside n3-2 acetyltransferase from bacillus anthracis
38c2ywiA_
not modelled 40.2 24 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical conserved protein;
PDBTitle: crystal structure of uncharacterized conserved protein from2 geobacillus kaustophilus
39d1piwa2
not modelled 36.8 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
40d1e3ja2
not modelled 36.8 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
41d1pl8a2
not modelled 32.5 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
42d3bula2
not modelled 31.7 7 Fold:Flavodoxin-like
Superfamily:Cobalamin (vitamin B12)-binding domain
Family:Cobalamin (vitamin B12)-binding domain
43d1kola2
not modelled 30.5 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
44c1bmtB_
not modelled 30.4 7 PDB header:methyltransferase
Chain: B: PDB Molecule:methionine synthase;
PDBTitle: how a protein binds b12: a 3.o angstrom x-ray structure of2 the b12-binding domains of methionine synthase
45c3ippA_
not modelled 30.1 15 PDB header:transferase
Chain: A: PDB Molecule:putative thiosulfate sulfurtransferase ynje;
PDBTitle: crystal structure of sulfur-free ynje
46c1uarA_
not modelled 28.2 15 PDB header:transferase
Chain: A: PDB Molecule:rhodanese;
PDBTitle: crystal structure of rhodanese from thermus thermophilus hb8
47d1f06a2
not modelled 27.0 15 Fold:FwdE/GAPDH domain-like
Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Family:Dihydrodipicolinate reductase-like
48d1qz9a_
not modelled 25.9 11 Fold:PLP-dependent transferase-like
Superfamily:PLP-dependent transferases
Family:Cystathionine synthase-like
49d1ja1a1
not modelled 25.8 19 Fold:Reductase/isomerase/elongation factor common domain
Superfamily:Riboflavin synthase domain-like
Family:NADPH-cytochrome p450 reductase FAD-binding domain-like
50c3olhA_
not modelled 23.4 10 PDB header:transferase
Chain: A: PDB Molecule:3-mercaptopyruvate sulfurtransferase;
PDBTitle: human 3-mercaptopyruvate sulfurtransferase
51d1zjca1
not modelled 22.2 14 Fold:Thermophilic metalloprotease-like
Superfamily:Thermophilic metalloprotease-like
Family:Thermophilic metalloprotease (M29)
52d1f20a1
not modelled 21.9 11 Fold:Reductase/isomerase/elongation factor common domain
Superfamily:Riboflavin synthase domain-like
Family:NADPH-cytochrome p450 reductase FAD-binding domain-like
53c3bcxA_
not modelled 21.2 15 PDB header:transferase
Chain: A: PDB Molecule:cdp-6-deoxy-l-threo-d-glycero-4-hexulose-3-
PDBTitle: e1 dehydrase
54d2c5sa1
not modelled 20.1 13 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:ThiI-like
55d1d1ta2
not modelled 19.5 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
56c1k98A_
not modelled 19.1 7 PDB header:transferase
Chain: A: PDB Molecule:methionine synthase;
PDBTitle: adomet complex of meth c-terminal fragment
57c2qsgX_
not modelled 18.2 14 PDB header:dna binding protein/dna
Chain: X: PDB Molecule:uv excision repair protein rad23;
PDBTitle: crystal structure of rad4-rad23 bound to a uv-damaged dna
58d1x3zb1
not modelled 17.9 14 Fold:XPC-binding domain
Superfamily:XPC-binding domain
Family:XPC-binding domain
59d1k92a1
not modelled 17.6 18 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
60d2npta1
not modelled 17.5 22 Fold:beta-Grasp (ubiquitin-like)
Superfamily:CAD & PB1 domains
Family:PB1 domain
61d1ddga1
not modelled 17.2 12 Fold:Reductase/isomerase/elongation factor common domain
Superfamily:Riboflavin synthase domain-like
Family:NADPH-cytochrome p450 reductase FAD-binding domain-like
62d1e3ia2
not modelled 16.8 7 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
63d1iz0a2
not modelled 16.6 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
64c1yj7A_
not modelled 16.1 17 PDB header:protein transport
Chain: A: PDB Molecule:escj;
PDBTitle: crystal structure of enteropathogenic e.coli (epec) type iii secretion2 system protein escj
65d1llua2
not modelled 15.9 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
66d1uufa2
not modelled 15.5 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
67d1p0fa2
not modelled 14.8 7 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
68c3nnkC_
not modelled 14.6 5 PDB header:transferase
Chain: C: PDB Molecule:ureidoglycine-glyoxylate aminotransferase;
PDBTitle: biochemical and structural characterization of a ureidoglycine2 aminotransferase in the klebsiella pneumoniae uric acid catabolic3 pathway
69c2wh7A_
not modelled 14.4 58 PDB header:hydrolase
Chain: A: PDB Molecule:hyaluronidase-phage associated;
PDBTitle: the partial structure of a group a streptpcoccal phage-2 encoded tail fibre hyaluronate lyase hylp2
70d1udxa3
not modelled 14.1 25 Fold:Obg GTP-binding protein C-terminal domain
Superfamily:Obg GTP-binding protein C-terminal domain
Family:Obg GTP-binding protein C-terminal domain
71d1jqba2
not modelled 13.2 11 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
72d1jvba2
not modelled 13.0 6 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
73d1uara2
not modelled 12.9 15 Fold:Rhodanese/Cell cycle control phosphatase
Superfamily:Rhodanese/Cell cycle control phosphatase
Family:Multidomain sulfurtransferase (rhodanese)
74c3aaxB_
not modelled 12.9 10 PDB header:transferase
Chain: B: PDB Molecule:putative thiosulfate sulfurtransferase;
PDBTitle: crystal structure of probable thiosulfate sulfurtransferase2 cysa3 (rv3117) from mycobacterium tuberculosis: monoclinic3 form
75d1uzhc1
not modelled 12.4 20 Fold:RuBisCO, small subunit
Superfamily:RuBisCO, small subunit
Family:RuBisCO, small subunit
76c2dkjB_
not modelled 12.3 10 PDB header:transferase
Chain: B: PDB Molecule:serine hydroxymethyltransferase;
PDBTitle: crystal structure of t.th.hb8 serine hydroxymethyltransferase
77c3hzuA_
not modelled 12.2 24 PDB header:transferase
Chain: A: PDB Molecule:thiosulfate sulfurtransferase ssea;
PDBTitle: crystal structure of probable thiosulfate sulfurtransferase ssea2 (rhodanese) from mycobacterium tuberculosis
78d1yb5a2
not modelled 11.7 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
79c3kifD_
not modelled 11.7 12 PDB header:sugar binding protein
Chain: D: PDB Molecule:5-bladed -propeller lectin;
PDBTitle: the crystal structures of two fragments truncated from 5-bladed -2 propeller lectin, tachylectin-2 (lib1-b7-18 and lib2-d2-15)
80d2igba1
not modelled 11.6 16 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
81d1rjwa2
not modelled 11.5 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
82c2l66B_
not modelled 11.4 27 PDB header:transcription regulator
Chain: B: PDB Molecule:transcriptional regulator, abrb family;
PDBTitle: the dna-recognition fold of sso7c4 suggests a new member of spovt-abrb2 superfamily from archaea.
83d1z7wa1
not modelled 10.6 13 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes
Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
84c3islA_
not modelled 10.6 7 PDB header:transferase
Chain: A: PDB Molecule:purine catabolism protein pucg;
PDBTitle: crystal structure of ureidoglycine-glyoxylate aminotransferase (pucg)2 from bacillus subtilis
85d1okga1
not modelled 10.3 23 Fold:Rhodanese/Cell cycle control phosphatase
Superfamily:Rhodanese/Cell cycle control phosphatase
Family:Multidomain sulfurtransferase (rhodanese)
86d1whua_
not modelled 10.1 56 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
Family:Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
87c2jkzB_
not modelled 9.9 25 PDB header:transferase
Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase;
PDBTitle: saccharomyces cerevisiae hypoxanthine-guanine2 phosphoribosyltransferase in complex with gmp (guanosine 5'3 -monophosphate) (orthorhombic crystal form)
88d1qora2
not modelled 9.9 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
89d2fzwa2
not modelled 9.6 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
90d1ykfa2
not modelled 9.5 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
91d1nula_
not modelled 9.5 6 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
92d1u3wa2
not modelled 9.2 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
93c1oftC_
not modelled 9.0 13 PDB header:bacterial cell division inhibitor
Chain: C: PDB Molecule:hypothetical protein pa3008;
PDBTitle: crystal structure of sula from pseudomonas aeruginosa
94d2v7fa1
not modelled 8.9 27 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Rps19E-like
95c3jyvT_
not modelled 8.8 33 PDB header:ribosome
Chain: T: PDB Molecule:s19e protein;
PDBTitle: structure of the 40s rrna and proteins and p/e trna for eukaryotic2 ribosome based on cryo-em map of thermomyces lanuginosus ribosome at3 8.9a resolution
96d1rbli_
not modelled 8.8 19 Fold:RuBisCO, small subunit
Superfamily:RuBisCO, small subunit
Family:RuBisCO, small subunit
97d1iwga3
not modelled 8.8 9 Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
98d2jhfa2
not modelled 8.6 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain
99d1cdoa2
not modelled 8.6 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Alcohol dehydrogenase-like, C-terminal domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0