Phyre 2 Results for P32051

Email	l.a.kelley@imperial.ac.uk
Description	P32051
Date	Wed Jan 25 15:20:49 GMT 2012
Unique Job ID	0527998f3d42f5f7

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template d1dcea2

Top template information

Fold:C2 domain-like
Superfamily:Rab geranylgeranyltransferase alpha-subunit, insert domain
Family:Rab geranylgeranyltransferase alpha-subunit, insert domain

Confidence and coverage

Confidence:

21.0%

Coverage:

7 residues ( 1% of your sequence) have been modelled with 21.0% confidence by the single highest scoring template.

You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.

Please note: You must be registered and logged in to use Phyrealarm.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M N R I Y R V I W N C T L Q V F Q A C S E L T R R A G K T S T V N L R K S S G L T T K F S R L T L G V L L A L S G S A S

Secondary structure

SS confidence

Disorder ? ? ? ?
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ?
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence G A S L E V D N D Q I T N I D T D V A Y D A Y L V G W Y G T G V L N I L A G G N A S L T T I T T S V I G A N E D S E G T

Secondary structure

SS confidence

Disorder ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
? ? ? ? ? ?
? ? ? ? ? ? ?
? ? ?
?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence V N V L G G T W R L Y D S G N N A R P L N V G Q S G T G T L N I K Q K G H V D G G Y L R L G S S T G G V G T V N V E G E

Secondary structure

SS confidence

Disorder
? ? ?
?
?
? ? ? ? ? ? ? ? ? ? ?
? ? ? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence D S V L T T E L F E I G S Y G T G S L N I T D K G Y V T S S I V A I L G Y Q A G S N G Q V V V E K G G E W L I K N N D S

Secondary structure

SS confidence

Disorder
?
? ?
? ?
?
? ? ? ?
?
? ?
? ?
?
?
? ?
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence S I E F Q I G N Q G T G E A T I R E G G L V T A E N T I I G G N A T G I G T L N V Q D Q D S V I T V R R L Y N G Y F G N

Secondary structure

SS confidence

Disorder ? ? ?
? ?
?
? ?
? ? ? ?
? ? ? ?
? ? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence G T V N I S N N G L I N N K E Y S L V G V Q D G S H G V V N V T D K G H W N F L G T G E A F R Y I Y I G D A G D G E L N

Secondary structure

SS confidence

Disorder
?
? ?
? ? ? ? ?
? ? ? ?
? ? ?
? ?

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence V S S E G K V D S G I I T A G M K E T G T G N I T V K D K N S V I T N L G T N L G Y D G H G E M N I S N Q G L V V S N G

Secondary structure

SS confidence

Disorder
? ?
? ? ? ? ?
? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ?
?
? ?
?

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence G S S L G Y G E T G V G N V S I T T G G M W E V N K N V Y T T I G V A G V G N L N I S D G G K F V S Q N I T F L G D K A

Secondary structure

SS confidence

Disorder ? ?
? ? ? ? ? ?
?
?
? ? ?
?
?
? ?
? ? ? ?
? ? ? ? ?

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence S G I G T L N L M D A T S S F D T V G I N V G N F G S G I V N V S N G A T L N S T G Y G F I G G N A S G K G I V N I S T

Secondary structure

SS confidence

Disorder ? ? ?
? ? ? ? ?
? ? ? ? ?
? ? ? ? ?
? ?
? ? ? ? ?
? ? ? ? ? ? ?
? ? ?

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence D S L W N L K T S S T N A Q L L Q V G V L G T G E L N I T T G G I V K A R D T Q I A L N D K S K G D V R V D G Q N S L L

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ?
? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence E T F N M Y V G T S G T G T L T L T N N G T L N V E G G E V Y L G V F E P A V G T L N I G A A H G E A A A D A G F I T N

Secondary structure

SS confidence

Disorder ? ? ?
? ? ? ?
?
? ?
? ? ? ? ? ? ? ? ? ? ? ?
?
?
? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence A T K V E F G L G E G V F V F N H T N N S D A G Y Q V D M L I T G D D K D G K V I H D A G H T V F N A G N T Y S G K T L

Secondary structure

SS confidence

Disorder ? ? ?
? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770 . . . . . . . . . 780

Sequence V N D G L L T I A S H T A D G V T G M G S S E V T I A N P G T L D I L A S T N S A G D Y T L T N A L K G D G L M R V Q L

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ?
? ? ? ? ? ? ? ?
? ? ?
? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence S S S D K M F G F T H A T G T E F A G V A Q L K D S T F T L E R D N T A A L T H A M L Q S D S E N T T S V K V G E Q S I

Secondary structure

SS confidence

Disorder ?
?
?
? ? ? ? ? ?
?
? ? ? ? ?
? ? ? ? ? ? ?
? ? ? ? ?
?
? ?
? ? ?
? ? ? ?

Disorder confidence

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900

Sequence G G L A M N G G T I I F D T D I P A A T L A E G Y I S V D T L V V G A G D Y T W K G R N Y Q V N G T G D V L I D V P K P

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ?
? ? ? ?

Disorder confidence

. . . . . . . . . 910 . . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960

Sequence W N D P M A N N P L T T L N L L E H D D S H V G V Q L V K A Q T V I G S G G S L T L R D L Q G D E V E A D K T L H I A Q

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ?

Disorder confidence

. . . . . . . . . 970 . . . . . . . . . 980 . . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020

Sequence N G T V V A E G D Y G F R L T T A P G N G L Y V N Y G L K A L N I H G G Q K L T L A E H G G A Y G A T A D M S A K I G G

Secondary structure

SS confidence

Disorder ? ? ?
?
?
? ? ? ? ? ? ? ? ? ? ?
?
? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050 . . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080

Sequence E G D L A I N T V R Q V S L S N G Q N D Y Q G A T Y V Q M G T L R T D A D G A L G N T R E L N I S N A A I V D L N G S T

Secondary structure

SS confidence

Disorder
?
?
?
?
? ? ? ? ? ? ? ? ? ? ?
?
?

Disorder confidence

. . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120 . . . . . . . . . 1130 . . . . . . . . . 1140

Sequence Q T V E T F T G Q M G S T V L F K E G A L T V N K G G I S Q G E L T G G G N L N V T G G T L A I E G L N A R Y N A L T S

Secondary structure

SS confidence

Disorder ? ? ? ? ?
? ?
? ?
? ? ?
?
? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180 . . . . . . . . . 1190 . . . . . . . . . 1200

Sequence I S P N A E V S L D N T Q G L G R G N I A N D G L L T L K N V T G E L R N S I S G K G I V S A T A R T D V E L D G D N S

Secondary structure

SS confidence

Disorder
? ?
? ? ? ? ? ? ?
? ? ?
?
? ? ? ?
?
?

Disorder confidence

. . . . . . . . . 1210 . . . . . . . . . 1220 . . . . . . . . . 1230 . . . . . . . . . 1240 . . . . . . . . . 1250 . . . . . . . . . 1260

Sequence R F V G Q F N I D T G S A L S V N E Q K N L G D A S V I N N G L L T I S T E R S W A M T H S I S G S G D V T K L G T G I

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1270 . . . . . . . . . 1280 . . . . . . . . . 1290 . . . . . . . . . 1300 . . . . . . . . . 1310 . . . . . . . . . 1320

Sequence L T L N N D S A A Y Q G T T D I V G G E I A F G S D S A I N M A S Q H I N I H N S G V M S G N V T T A G D M N V M P G G

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ?
?
? ?
? ? ?
?
? ?

Disorder confidence

. . . . .

Sequence G T A C R

Secondary structure

SS confidence

Disorder ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 1dce chain A domain 2

Region: 3 - 9
Aligned: 7
Modelled: 7
Confidence: 21.0%
Identity: 57%
Fold: C2 domain-like
Superfamily: Rab geranylgeranyltransferase alpha-subunit, insert domain
Family: Rab geranylgeranyltransferase alpha-subunit, insert domain

Phyre2

PDB 2vxa chain L

Region: 2 - 8
Aligned: 7
Modelled: 7
Confidence: 16.4%
Identity: 14%
PDB header:flavoprotein
Chain: L: PDB Molecule:dodecin;
PDBTitle: h.halophila dodecin in complex with riboflavin

Phyre2

PDB 2pe4 chain A

Region: 2 - 10
Aligned: 9
Modelled: 9
Confidence: 15.8%
Identity: 44%
PDB header:hydrolase
Chain: A: PDB Molecule:hyaluronidase-1;
PDBTitle: structure of human hyaluronidase 1, a hyaluronan hydrolyzing enzyme2 involved in tumor growth and angiogenesis

Phyre2

PDB 1b26 chain A domain 2

Region: 2 - 14
Aligned: 13
Modelled: 13
Confidence: 11.9%
Identity: 31%
Fold: Aminoacid dehydrogenase-like, N-terminal domain
Superfamily: Aminoacid dehydrogenase-like, N-terminal domain
Family: Aminoacid dehydrogenases

Phyre2

PDB 1u46 chain A

Region: 3 - 19
Aligned: 17
Modelled: 17
Confidence: 11.6%
Identity: 12%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 1euz chain A domain 2

Region: 2 - 14
Aligned: 13
Modelled: 13
Confidence: 10.9%
Identity: 23%
Fold: Aminoacid dehydrogenase-like, N-terminal domain
Superfamily: Aminoacid dehydrogenase-like, N-terminal domain
Family: Aminoacid dehydrogenases

Phyre2

PDB 2atm chain A

Region: 3 - 10
Aligned: 8
Modelled: 8
Confidence: 10.8%
Identity: 38%
PDB header:hydrolase
Chain: A: PDB Molecule:hyaluronoglucosaminidase;
PDBTitle: crystal structure of the recombinant allergen ves v 2

Phyre2

PDB 3oqt chain P

Region: 1 - 8
Aligned: 8
Modelled: 8
Confidence: 10.6%
Identity: 63%
PDB header:flavoprotein
Chain: P: PDB Molecule:rv1498a protein;
PDBTitle: crystal structure of rv1498a protein from mycobacterium tuberculosis

Phyre2

PDB 2hw2 chain A

Region: 1 - 5
Aligned: 5
Modelled: 5
Confidence: 10.6%
Identity: 80%
PDB header:transferase
Chain: A: PDB Molecule:rifampin adp-ribosyl transferase;
PDBTitle: crystal structure of rifampin adp-ribosyl transferase in2 complex with rifampin

Phyre2

PDB 1bvu chain A domain 2

Region: 2 - 14
Aligned: 13
Modelled: 13
Confidence: 10.5%
Identity: 23%
Fold: Aminoacid dehydrogenase-like, N-terminal domain
Superfamily: Aminoacid dehydrogenase-like, N-terminal domain
Family: Aminoacid dehydrogenases

Phyre2

PDB 2vag chain A

Region: 3 - 19
Aligned: 17
Modelled: 17
Confidence: 10.1%
Identity: 12%
PDB header:transferase
Chain: A: PDB Molecule:dual specificity protein kinase clk1;
PDBTitle: crystal structure of di-phosphorylated human clk1 in2 complex with a novel substituted indole inhibitor

Phyre2

PDB 1wv8 chain A domain 1

Region: 5 - 21
Aligned: 17
Modelled: 17
Confidence: 10.1%
Identity: 24%
Fold: TTHA1013/TTHA0281-like
Superfamily: TTHA1013/TTHA0281-like
Family: TTHA1013-like

Phyre2

PDB 3s2x chain B

Region: 4 - 9
Aligned: 6
Modelled: 6
Confidence: 9.9%
Identity: 50%
PDB header:transferase
Chain: B: PDB Molecule:acetyl-coa synthase subunit alpha;
PDBTitle: structure of acetyl-coenzyme a synthase alpha subunit c-terminal2 domain

Phyre2

PDB 1hwx chain A domain 2

Region: 1 - 16
Aligned: 16
Modelled: 16
Confidence: 9.7%
Identity: 13%
Fold: Aminoacid dehydrogenase-like, N-terminal domain
Superfamily: Aminoacid dehydrogenase-like, N-terminal domain
Family: Aminoacid dehydrogenases

Phyre2

PDB 1gxy chain A

Region: 1 - 16
Aligned: 16
Modelled: 16
Confidence: 9.4%
Identity: 25%
Fold: ADP-ribosylation
Superfamily: ADP-ribosylation
Family: Ecto-ART

Phyre2

PDB 1iq9 chain A

Region: 2 - 17
Aligned: 16
Modelled: 16
Confidence: 9.3%
Identity: 13%
Fold: Snake toxin-like
Superfamily: Snake toxin-like
Family: Snake venom toxins

Phyre2

PDB 1gtm chain A domain 2

Region: 2 - 14
Aligned: 13
Modelled: 13
Confidence: 9.2%
Identity: 23%
Fold: Aminoacid dehydrogenase-like, N-terminal domain
Superfamily: Aminoacid dehydrogenase-like, N-terminal domain
Family: Aminoacid dehydrogenases

Phyre2

PDB 2hly chain A domain 1

Region: 2 - 8
Aligned: 7
Modelled: 7
Confidence: 8.9%
Identity: 86%
Fold: Cysteine proteinases
Superfamily: Cysteine proteinases
Family: Atu2299-like

Phyre2

PDB 1bgv chain A domain 2

Region: 2 - 14
Aligned: 13
Modelled: 13
Confidence: 8.8%
Identity: 38%
Fold: Aminoacid dehydrogenase-like, N-terminal domain
Superfamily: Aminoacid dehydrogenase-like, N-terminal domain
Family: Aminoacid dehydrogenases

Phyre2

PDB 1ntx chain A

Region: 2 - 17
Aligned: 16
Modelled: 16
Confidence: 8.6%
Identity: 19%
Fold: Snake toxin-like
Superfamily: Snake toxin-like
Family: Snake venom toxins