Phyre 2 Results for P75830

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Email | l.a.kelley@imperial.ac.uk
Description | P75830
Date | Thu Jan 5 12:14:47 GMT 2012
Unique Job ID | 038a20397b4cc51f

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c3h9iB_
Top template information
PDB header:transport protein Chain: B: PDB Molecule:cation efflux system protein cusb; PDBTitle: crystal structure of the membrane fusion protein cusb from escherichia2 coli
Confidence and coverage
Confidence: | 100.0% | Coverage: | 79%
292 residues ( 79% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | K | K | R | K | T | V | K | K | R | Y | V | I | A | L | V | I | V | I | A | G | L | I | T | L | W | R | I | L | N | A | P | V | P | T | Y | Q | T | L | I | V | R | P | G | D | L | Q | Q | S | V | L | A | T | G | K | L | D | A | L | R
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  | ? |  |  |  |  |  |  |  | ? |  | ? |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  | ? |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | K | V | D | V | G | A | Q | V | S | G | Q | L | K | T | L | S | V | A | I | G | D | K | V | K | K | D | Q | L | L | G | V | I | D | P | E | Q | A | E | N | Q | I | K | E | V | E | A | T | L | M | E | L | R | A | Q | R | Q | Q | A | E | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  | ? |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | E | L | K | L | A | R | V | T | Y | S | R | Q | Q | R | L | A | Q | T | K | A | V | S | Q | Q | D | L | D | T | A | A | T | E | M | A | V | K | Q | A | Q | I | G | T | I | D | A | Q | I | K | R | N | Q | A | S | L | D | T | A | K | T | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | L | D | Y | T | R | I | V | A | P | M | A | G | E | V | T | Q | I | T | T | L | Q | G | Q | T | V | I | A | A | Q | Q | A | P | N | I | L | T | L | A | D | M | S | A | M | L | V | K | A | Q | V | S | E | A | D | V | I | H | L | K | P | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | Q | K | A | W | F | T | V | L | G | D | P | L | T | R | Y | E | G | Q | I | K | D | V | L | P | T | P | E | K | V | N | D | A | I | F | Y | Y | A | R | F | E | V | P | N | P | N | G | L | L | R | L | D | M | T | A | Q | V | H | I | Q | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | T | D | V | K | N | V | L | T | I | P | L | S | A | L | G | D | P | V | G | D | N | R | Y | K | V | K | L | L | R | N | G | E | T | R | E | R | E | V | T | I | G | A | R | N | D | T | D | V | E | I | V | K | G | L | E | A | G | D | E | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? |  | ? |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | .
Sequence |  | V | I | G | E | A | K | P | G | A | A | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c3h9iB_ |

### PDB 3h9i chain B

Region: 31 - 366
Aligned: 292
Modelled: 292
Confidence: 100.0%
Identity: 20%
PDB header:transport protein
Chain: B: PDB Molecule:cation efflux system protein cusb;
PDBTitle: crystal structure of the membrane fusion protein cusb from escherichia2 coli

Phyre2
2 |
| c3fppB_ |

### PDB 3fpp chain B

Region: 42 - 308
Aligned: 267
Modelled: 267
Confidence: 100.0%
Identity: 99%
PDB header:membrane protein
Chain: B: PDB Molecule:macrolide-specific efflux protein maca;
PDBTitle: crystal structure of e.coli maca

Phyre2
3 |
| c2f1mA_ |

### PDB 2f1m chain A

Region: 49 - 298
Aligned: 228
Modelled: 243
Confidence: 99.9%
Identity: 23%
PDB header:transport protein
Chain: A: PDB Molecule:acriflavine resistance protein a;
PDBTitle: conformational flexibility in the multidrug efflux system protein acra

Phyre2
4 |
| c3lnnB_ |

### PDB 3lnn chain B

Region: 47 - 301
Aligned: 241
Modelled: 244
Confidence: 99.8%
Identity: 19%
PDB header:metal transport
Chain: B: PDB Molecule:membrane fusion protein (mfp) heavy metal cation efflux
PDBTitle: crystal structure of zneb from cupriavidus metallidurans

Phyre2
5 |
| d1vf7a_ |

### PDB 1vf7 chain A

Region: 47 - 301
Aligned: 224
Modelled: 227
Confidence: 99.8%
Identity: 23%
Fold: HlyD-like secretion proteins
Superfamily: HlyD-like secretion proteins
Family: HlyD-like secretion proteins

Phyre2
6 |
| c1t5eB_ |

### PDB 1t5e chain B

Region: 51 - 298
Aligned: 217
Modelled: 220
Confidence: 99.8%
Identity: 20%
PDB header:transport protein
Chain: B: PDB Molecule:multidrug resistance protein mexa;
PDBTitle: the structure of mexa

Phyre2
7 |
| c2k33A_ |

### PDB 2k33 chain A

Region: 61 - 231
Aligned: 113
Modelled: 115
Confidence: 98.6%
Identity: 27%
PDB header:membrane protein, transport protein
Chain: A: PDB Molecule:acra;
PDBTitle: solution structure of an n-glycosylated protein using in2 vitro glycosylation

Phyre2
8 |
| c2b8gA_ |

### PDB 2b8g chain A

Region: 63 - 94
Aligned: 32
Modelled: 32
Confidence: 96.9%
Identity: 28%
PDB header:biosynthetic protein
Chain: A: PDB Molecule:biotin/lipoyl attachment protein;
PDBTitle: solution structure of bacillus subtilis blap biotinylated-2 form (energy minimized mean structure)

Phyre2
9 |
| d1dcza_ |

### PDB 1dcz chain A

Region: 63 - 94
Aligned: 32
Modelled: 32
Confidence: 96.8%
Identity: 28%
Fold: Barrel-sandwich hybrid
Superfamily: Single hybrid motif
Family: Biotinyl/lipoyl-carrier proteins and domains

Phyre2
10 |
| c2ejgD_ |

### PDB 2ejg chain D

Region: 64 - 93
Aligned: 30
Modelled: 30
Confidence: 96.8%
Identity: 33%
PDB header:ligase
Chain: D: PDB Molecule:149aa long hypothetical methylmalonyl-coa decarboxylase
PDBTitle: crystal structure of the biotin protein ligase (mutation r48a) and2 biotin carboxyl carrier protein complex from pyrococcus horikoshii3 ot3

Phyre2
11 |
| d1o78a_ |

### PDB 1o78 chain A

Region: 64 - 94
Aligned: 31
Modelled: 31
Confidence: 96.6%
Identity: 29%
Fold: Barrel-sandwich hybrid
Superfamily: Single hybrid motif
Family: Biotinyl/lipoyl-carrier proteins and domains

Phyre2
12 |
| c2dn8A_ |

### PDB 2dn8 chain A

Region: 63 - 92
Aligned: 30
Modelled: 30
Confidence: 96.5%
Identity: 17%
PDB header:ligase
Chain: A: PDB Molecule:acetyl-coa carboxylase 2;
PDBTitle: solution structure of rsgi ruh-053, an apo-biotin carboxy2 carrier protein from human transcarboxylase

Phyre2
13 |
| c2ejmA_ |

### PDB 2ejm chain A

Region: 64 - 94
Aligned: 31
Modelled: 31
Confidence: 96.4%
Identity: 32%
PDB header:ligase
Chain: A: PDB Molecule:methylcrotonoyl-coa carboxylase subunit alpha;
PDBTitle: solution structure of ruh-072, an apo-biotnyl domain form2 human acetyl coenzyme a carboxylase

Phyre2
14 |
| d1bdoa_ |

### PDB 1bdo chain A

Region: 54 - 93
Aligned: 40
Modelled: 40
Confidence: 96.4%
Identity: 30%
Fold: Barrel-sandwich hybrid
Superfamily: Single hybrid motif
Family: Biotinyl/lipoyl-carrier proteins and domains

Phyre2
15 |
| c2kccA_ |

### PDB 2kcc chain A

Region: 63 - 94
Aligned: 32
Modelled: 32
Confidence: 96.4%
Identity: 16%
PDB header:ligase
Chain: A: PDB Molecule:acetyl-coa carboxylase 2;
PDBTitle: solution structure of biotinoyl domain from human acetyl-2 coa carboxylase 2

Phyre2
16 |
| c3n6rK_ |

### PDB 3n6r chain K

Region: 61 - 93
Aligned: 33
Modelled: 33
Confidence: 96.3%
Identity: 12%
PDB header:ligase
Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit;
PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc)

Phyre2
17 |
| c2l5tA_ |

### PDB 2l5t chain A

Region: 61 - 94
Aligned: 34
Modelled: 34
Confidence: 96.3%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:lipoamide acyltransferase;
PDBTitle: solution nmr structure of e2 lipoyl domain from thermoplasma2 acidophilum

Phyre2
18 |
| d1iyua_ |

### PDB 1iyu chain A

Region: 61 - 94
Aligned: 34
Modelled: 34
Confidence: 96.2%
Identity: 29%
Fold: Barrel-sandwich hybrid
Superfamily: Single hybrid motif
Family: Biotinyl/lipoyl-carrier proteins and domains

Phyre2
19 |
| d1ghja_ |

### PDB 1ghj chain A

Region: 61 - 94
Aligned: 34
Modelled: 34
Confidence: 96.0%
Identity: 26%
Fold: Barrel-sandwich hybrid
Superfamily: Single hybrid motif
Family: Biotinyl/lipoyl-carrier proteins and domains

Phyre2
20 |
| d1k8ma_ |

### PDB 1k8m chain A

Region: 61 - 95
Aligned: 35
Modelled: 35
Confidence: 95.7%
Identity: 23%
Fold: Barrel-sandwich hybrid
Superfamily: Single hybrid motif
Family: Biotinyl/lipoyl-carrier proteins and domains

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c3h9iB_ |
|  | 100.0 | 20 | PDB header:transport protein Chain: B: PDB Molecule:cation efflux system protein cusb; PDBTitle: crystal structure of the membrane fusion protein cusb from escherichia2 coli
2 | c3fppB_ |
|  | 100.0 | 99 | PDB header:membrane protein Chain: B: PDB Molecule:macrolide-specific efflux protein maca; PDBTitle: crystal structure of e.coli maca
3 | c2f1mA_ |
|  | 99.9 | 23 | PDB header:transport protein Chain: A: PDB Molecule:acriflavine resistance protein a; PDBTitle: conformational flexibility in the multidrug efflux system protein acra
4 | c3lnnB_ |
|  | 99.8 | 19 | PDB header:metal transport Chain: B: PDB Molecule:membrane fusion protein (mfp) heavy metal cation efflux PDBTitle: crystal structure of zneb from cupriavidus metallidurans
5 | d1vf7a_ |
|  | 99.8 | 23 | Fold:HlyD-like secretion proteins Superfamily:HlyD-like secretion proteins Family:HlyD-like secretion proteins
6 | c1t5eB_ |
|  | 99.8 | 20 | PDB header:transport protein Chain: B: PDB Molecule:multidrug resistance protein mexa; PDBTitle: the structure of mexa
7 | c2k33A_ |
|  | 98.6 | 27 | PDB header:membrane protein, transport protein Chain: A: PDB Molecule:acra; PDBTitle: solution structure of an n-glycosylated protein using in2 vitro glycosylation
8 | c2b8gA_ |
|  | 96.9 | 28 | PDB header:biosynthetic protein Chain: A: PDB Molecule:biotin/lipoyl attachment protein; PDBTitle: solution structure of bacillus subtilis blap biotinylated-2 form (energy minimized mean structure)
9 | d1dcza_ |
|  | 96.8 | 28 | Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains
10 | c2ejgD_ |
|  | 96.8 | 33 | PDB header:ligase Chain: D: PDB Molecule:149aa long hypothetical methylmalonyl-coa decarboxylase PDBTitle: crystal structure of the biotin protein ligase (mutation r48a) and2 biotin carboxyl carrier protein complex from pyrococcus horikoshii3 ot3
11 | d1o78a_ |
|  | 96.6 | 29 | Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains
12 | c2dn8A_ |
|  | 96.5 | 17 | PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of rsgi ruh-053, an apo-biotin carboxy2 carrier protein from human transcarboxylase
13 | c2ejmA_ |
|  | 96.4 | 32 | PDB header:ligase Chain: A: PDB Molecule:methylcrotonoyl-coa carboxylase subunit alpha; PDBTitle: solution structure of ruh-072, an apo-biotnyl domain form2 human acetyl coenzyme a carboxylase
14 | d1bdoa_ |
|  | 96.4 | 30 | Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains
15 | c2kccA_ |
|  | 96.4 | 16 | PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of biotinoyl domain from human acetyl-2 coa carboxylase 2
16 | c3n6rK_ |
|  | 96.3 | 12 | PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc)
17 | c2l5tA_ |
|  | 96.3 | 24 | PDB header:transferase Chain: A: PDB Molecule:lipoamide acyltransferase; PDBTitle: solution nmr structure of e2 lipoyl domain from thermoplasma2 acidophilum
18 | d1iyua_ |
|  | 96.2 | 29 | Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains
19 | d1ghja_ |
|  | 96.0 | 26 | Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains
20 | d1k8ma_ |
|  | 95.7 | 23 | Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains
21 | d2f3ga_ |
| not modelled | 95.7 | 25 | Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like
22 | d2gpra_ |
| not modelled | 95.6 | 32 | Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like
23 | d1glaf_ |
| not modelled | 95.5 | 25 | Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like
24 | d1qjoa_ |
| not modelled | 95.4 | 35 | Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains
25 | d1y8ob1 |
| not modelled | 95.2 | 23 | Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains
26 | d1laba_ |
| not modelled | 94.9 | 23 | Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains
27 | d1gpra_ |
| not modelled | 94.9 | 30 | Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like
28 | d1gjxa_ |
| not modelled | 94.8 | 37 | Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains
29 | d2pnrc1 |
| not modelled | 94.8 | 23 | Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains
30 | c2qf7A_ |
| not modelled | 94.4 | 25 | PDB header:ligase Chain: A: PDB Molecule:pyruvate carboxylase protein; PDBTitle: crystal structure of a complete multifunctional pyruvate carboxylase2 from rhizobium etli
31 | c2q8iB_ |
| not modelled | 94.3 | 22 | PDB header:transferase Chain: B: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase component of PDBTitle: pyruvate dehydrogenase kinase isoform 3 in complex with antitumor drug2 radicicol
32 | d1pmra_ |
| not modelled | 94.2 | 27 | Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains
33 | d1uoua3 |
| not modelled | 93.8 | 14 | Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain
34 | d1brwa3 |
| not modelled | 93.6 | 31 | Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain
35 | c2dncA_ |
| not modelled | 93.6 | 28 | PDB header:transferase Chain: A: PDB Molecule:pyruvate dehydrogenase protein x component; PDBTitle: solution structure of rsgi ruh-054, a lipoyl domain from2 human 2-oxoacid dehydrogenase
36 | c2dneA_ |
| not modelled | 93.2 | 13 | PDB header:transferase Chain: A: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase PDBTitle: solution structure of rsgi ruh-058, a lipoyl domain of2 human 2-oxoacid dehydrogenase
37 | d2tpta3 |
| not modelled | 93.1 | 26 | Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain
38 | c2jkuA_ |
| not modelled | 92.5 | 30 | PDB header:ligase Chain: A: PDB Molecule:propionyl-coa carboxylase alpha chain, PDBTitle: crystal structure of the n-terminal region of the biotin2 acceptor domain of human propionyl-coa carboxylase
39 | c1otpA_ |
| not modelled | 91.5 | 26 | PDB header:phosphorylase Chain: A: PDB Molecule:thymidine phosphorylase; PDBTitle: structural and theoretical studies suggest domain movement produces an2 active conformation of thymidine phosphorylase
40 | c3h5qA_ |
| not modelled | 89.5 | 40 | PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside phosphorylase; PDBTitle: crystal structure of a putative pyrimidine-nucleoside phosphorylase2 from staphylococcus aureus
41 | c2dsjA_ |
| not modelled | 89.5 | 17 | PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside (thymidine) phosphorylase; PDBTitle: crystal structure of project id tt0128 from thermus thermophilus hb8
42 | c2j0fC_ |
| not modelled | 89.4 | 17 | PDB header:transferase Chain: C: PDB Molecule:thymidine phosphorylase; PDBTitle: structural basis for non-competitive product inhibition in2 human thymidine phosphorylase: implication for drug design
43 | c1brwB_ |
| not modelled | 88.1 | 37 | PDB header:transferase Chain: B: PDB Molecule:protein (pyrimidine nucleoside phosphorylase); PDBTitle: the crystal structure of pyrimidine nucleoside2 phosphorylase in a closed conformation
44 | c3fmcC_ |
| not modelled | 85.1 | 12 | PDB header:hydrolase Chain: C: PDB Molecule:putative succinylglutamate desuccinylase / aspartoacylase; PDBTitle: crystal structure of a putative succinylglutamate desuccinylase /2 aspartoacylase family protein (sama_0604) from shewanella amazonensis3 sb2b at 1.80 a resolution
45 | c2hsiB_ |
| not modelled | 83.6 | 26 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative peptidase m23; PDBTitle: crystal structure of putative peptidase m23 from2 pseudomonas aeruginosa, new york structural genomics3 consortium
46 | c2gu1A_ |
| not modelled | 83.4 | 23 | PDB header:hydrolase Chain: A: PDB Molecule:zinc peptidase; PDBTitle: crystal structure of a zinc containing peptidase from2 vibrio cholerae
47 | c2qj8B_ |
| not modelled | 82.0 | 18 | PDB header:hydrolase Chain: B: PDB Molecule:mlr6093 protein; PDBTitle: crystal structure of an aspartoacylase family protein (mlr6093) from2 mesorhizobium loti maff303099 at 2.00 a resolution
48 | c2aukA_ |
| not modelled | 80.2 | 25 | PDB header:transferase Chain: A: PDB Molecule:dna-directed rna polymerase beta' chain; PDBTitle: structure of e. coli rna polymerase beta' g/g' insert
49 | d1qwya_ |
| not modelled | 78.9 | 30 | Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Peptidoglycan hydrolase LytM
50 | d1qpoa2 |
| not modelled | 70.9 | 22 | Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like
51 | d1ci3m2 |
| not modelled | 70.9 | 31 | Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain
52 | d1e2wa2 |
| not modelled | 70.4 | 44 | Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain
53 | c3d4rE_ |
| not modelled | 70.2 | 14 | PDB header:unknown function Chain: E: PDB Molecule:domain of unknown function from the pfam-b_34464 family; PDBTitle: crystal structure of a duf2118 family protein (mmp0046) from2 methanococcus maripaludis at 2.20 a resolution
54 | c3na6A_ |
| not modelled | 70.2 | 14 | PDB header:hydrolase Chain: A: PDB Molecule:succinylglutamate desuccinylase/aspartoacylase; PDBTitle: crystal structure of a succinylglutamate desuccinylase (tm1040_2694)2 from silicibacter sp. tm1040 at 2.00 a resolution
55 | c2b44A_ |
| not modelled | 69.2 | 30 | PDB header:hydrolase Chain: A: PDB Molecule:glycyl-glycine endopeptidase lytm; PDBTitle: truncated s. aureus lytm, p 32 2 1 crystal form
56 | c3cdxB_ |
| not modelled | 68.2 | 23 | PDB header:hydrolase Chain: B: PDB Molecule:succinylglutamatedesuccinylase/aspartoacylase; PDBTitle: crystal structure of2 succinylglutamatedesuccinylase/aspartoacylase from3 rhodobacter sphaeroides
57 | d1o4ua2 |
| not modelled | 67.4 | 20 | Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like
58 | c2xhaB_ |
| not modelled | 65.3 | 33 | PDB header:transcription Chain: B: PDB Molecule:transcription antitermination protein nusg; PDBTitle: crystal structure of domain 2 of thermotoga maritima n-utilization2 substance g (nusg)
59 | c2aujD_ |
| not modelled | 65.0 | 31 | PDB header:transferase Chain: D: PDB Molecule:dna-directed rna polymerase beta' chain; PDBTitle: structure of thermus aquaticus rna polymerase beta'-subunit2 insert
60 | d1qapa2 |
| not modelled | 62.2 | 26 | Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like
61 | c3it5B_ |
| not modelled | 61.9 | 33 | PDB header:hydrolase Chain: B: PDB Molecule:protease lasa; PDBTitle: crystal structure of the lasa virulence factor from pseudomonas2 aeruginosa
62 | c2xhcA_ |
| not modelled | 55.6 | 33 | PDB header:transcription Chain: A: PDB Molecule:transcription antitermination protein nusg; PDBTitle: crystal structure of thermotoga maritima n-utilization substance g2 (nusg)
63 | d1ep3b1 |
| not modelled | 54.3 | 8 | Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:Ferredoxin reductase FAD-binding domain-like
64 | c3nyyA_ |
| not modelled | 54.1 | 37 | PDB header:hydrolase Chain: A: PDB Molecule:putative glycyl-glycine endopeptidase lytm; PDBTitle: crystal structure of a putative glycyl-glycine endopeptidase lytm2 (rumgna_02482) from ruminococcus gnavus atcc 29149 at 1.60 a3 resolution
65 | c3gnnA_ |
| not modelled | 50.6 | 11 | PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide2 pyrophosphorylase from burkholderi pseudomallei
66 | c1o4uA_ |
| not modelled | 50.4 | 16 | PDB header:transferase Chain: A: PDB Molecule:type ii quinolic acid phosphoribosyltransferase; PDBTitle: crystal structure of a nicotinate nucleotide pyrophosphorylase2 (tm1645) from thermotoga maritima at 2.50 a resolution
67 | c1e2vB_ |
| not modelled | 49.3 | 44 | PDB header:electron transport proteins Chain: B: PDB Molecule:cytochrome f; PDBTitle: n153q mutant of cytochrome f from chlamydomonas reinhardtii
68 | c1ctmA_ |
| not modelled | 49.2 | 44 | PDB header:electron transport(cytochrome) Chain: A: PDB Molecule:cytochrome f; PDBTitle: crystal structure of chloroplast cytochrome f reveals a2 novel cytochrome fold and unexpected heme ligation
69 | c2jbmA_ |
| not modelled | 48.6 | 10 | PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: qprtase structure from human
70 | c2jxmB_ |
| not modelled | 48.4 | 56 | PDB header:electron transport Chain: B: PDB Molecule:cytochrome f; PDBTitle: ensemble of twenty structures of the prochlorothrix2 hollandica plastocyanin- cytochrome f complex
71 | c3csqC_ |
| not modelled | 44.5 | 40 | PDB header:hydrolase Chain: C: PDB Molecule:morphogenesis protein 1; PDBTitle: crystal and cryoem structural studies of a cell wall2 degrading enzyme in the bacteriophage phi29 tail
72 | c1q90A_ |
| not modelled | 44.4 | 44 | PDB header:photosynthesis Chain: A: PDB Molecule:apocytochrome f; PDBTitle: structure of the cytochrome b6f (plastohydroquinone : plastocyanin2 oxidoreductase) from chlamydomonas reinhardtii
73 | c1tu2B_ |
| not modelled | 43.9 | 31 | PDB header:electron transport Chain: B: PDB Molecule:apocytochrome f; PDBTitle: the complex of nostoc cytochrome f and plastocyanin determin with2 paramagnetic nmr. based on the structures of cytochrome f and3 plastocyanin, 10 structures
74 | c3a8jF_ |
| not modelled | 42.8 | 24 | PDB header:transferase/transport protein Chain: F: PDB Molecule:glycine cleavage system h protein; PDBTitle: crystal structure of et-ehred complex
75 | c1qapA_ |
| not modelled | 42.4 | 20 | PDB header:glycosyltransferase Chain: A: PDB Molecule:quinolinic acid phosphoribosyltransferase; PDBTitle: quinolinic acid phosphoribosyltransferase with bound2 quinolinic acid
76 | c3pajA_ |
| not modelled | 42.1 | 19 | PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase, carboxylating; PDBTitle: 2.00 angstrom resolution crystal structure of a quinolinate2 phosphoribosyltransferase from vibrio cholerae o1 biovar eltor str.3 n16961
77 | d1tu2b2 |
| not modelled | 41.7 | 31 | Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain
78 | c1tqqC_ |
| not modelled | 41.7 | 9 | PDB header:transport protein Chain: C: PDB Molecule:outer membrane protein tolc; PDBTitle: structure of tolc in complex with hexamminecobalt
79 | d1ek9a_ |
| not modelled | 40.8 | 9 | Fold:Outer membrane efflux proteins (OEP) Superfamily:Outer membrane efflux proteins (OEP) Family:Outer membrane efflux proteins (OEP)
80 | c2e75C_ |
| not modelled | 40.8 | 38 | PDB header:photosynthesis Chain: C: PDB Molecule:apocytochrome f; PDBTitle: crystal structure of the cytochrome b6f complex with 2-nonyl-4-2 hydroxyquinoline n-oxide (nqno) from m.laminosus
81 | c1yc9A_ |
| not modelled | 40.0 | 17 | PDB header:membrane protein Chain: A: PDB Molecule:multidrug resistance protein; PDBTitle: the crystal structure of the outer membrane protein vcec from the2 bacterial pathogen vibrio cholerae at 1.8 resolution
82 | c2b7pA_ |
| not modelled | 39.8 | 13 | PDB header:transferase Chain: A: PDB Molecule:probable nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of quinolinic acid phosphoribosyltransferase from2 helicobacter pylori
83 | c2zpmA_ |
| not modelled | 39.7 | 40 | PDB header:hydrolase Chain: A: PDB Molecule:regulator of sigma e protease; PDBTitle: crystal structure analysis of pdz domain b
84 | d1wp1a_ |
| not modelled | 39.6 | 17 | Fold:Outer membrane efflux proteins (OEP) Superfamily:Outer membrane efflux proteins (OEP) Family:Outer membrane efflux proteins (OEP)
85 | c3tqvA_ |
| not modelled | 38.2 | 11 | PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: structure of the nicotinate-nucleotide pyrophosphorylase from2 francisella tularensis.
86 | c3pikA_ |
| not modelled | 33.9 | 12 | PDB header:transport protein Chain: A: PDB Molecule:cation efflux system protein cusc; PDBTitle: outer membrane protein cusc
87 | c3iftA_ |
| not modelled | 33.8 | 20 | PDB header:oxidoreductase Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: crystal structure of glycine cleavage system protein h from2 mycobacterium tuberculosis, using x-rays from the compact light3 source.
88 | c1x1oC_ |
| not modelled | 32.2 | 19 | PDB header:transferase Chain: C: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of project id tt0268 from thermus thermophilus hb8
89 | c3l0gD_ |
| not modelled | 30.7 | 17 | PDB header:transferase Chain: D: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide pyrophosphorylase from2 ehrlichia chaffeensis at 2.05a resolution
90 | d1hcza2 |
| not modelled | 30.4 | 44 | Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain
91 | c1qpoA_ |
| not modelled | 27.6 | 16 | PDB header:transferase Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase; PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis
92 | c3qglD_ |
| not modelled | 26.9 | 13 | PDB header:protein binding Chain: D: PDB Molecule:sorting nexin-27; PDBTitle: crystal structure of pdz domain of sorting nexin 27 (snx27) in complex2 with the eseskv peptide corresponding to the c-terminal tail of girk3
93 | d2piaa1 |
| not modelled | 26.3 | 14 | Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:Ferredoxin reductase FAD-binding domain-like
94 | d1onla_ |
| not modelled | 23.2 | 17 | Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains
95 | c3mxuA_ |
| not modelled | 21.7 | 20 | PDB header:oxidoreductase Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: crystal structure of glycine cleavage system protein h from bartonella2 henselae
96 | d1vf5c2 |
| not modelled | 21.1 | 38 | Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain
97 | c2v90E_ |
| not modelled | 19.4 | 13 | PDB header:protein-binding Chain: E: PDB Molecule:pdz domain-containing protein 3; PDBTitle: crystal structure of the 3rd pdz domain of intestine- and2 kidney-enriched pdz domain ikepp (pdzd3)
98 | c2ka7A_ |
| not modelled | 18.3 | 22 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: nmr solution structure of tm0212 at 40 c
99 | d1udxa3 |
| not modelled | 17.9 | 37 | Fold:Obg GTP-binding protein C-terminal domain Superfamily:Obg GTP-binding protein C-terminal domain Family:Obg GTP-binding protein C-terminal domain

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0