BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (229 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P0AGJ3 tRNA guanosine-2'-O-methyltransferase n=231 Tax=...   477   e-133
UniRef50_Q15Z06 tRNA (Guanosine-2'-O-)-methyltransferase n=2 Tax...   289   4e-77
UniRef50_B5JS83 tRNA (Guanosine-2-O)-methyltransferase n=3 Tax=B...   237   2e-61
UniRef50_C7R944 tRNA guanosine-2'-O-methyltransferase n=1 Tax=Ka...   236   6e-61
UniRef50_Q0VRD7 RNA methyltransferase, TrmH family, group 3 n=2 ...   234   2e-60
UniRef50_A3IM41 RRNA methylase SpoU n=1 Tax=Cyanothece sp. CCY01...   219   7e-56
UniRef50_C1XS02 rRNA methylase n=2 Tax=Bacteria RepID=C1XS02_9DEIN    218   1e-55
UniRef50_B3QXG6 tRNA guanosine-2'-O-methyltransferase n=1 Tax=Ch...   210   3e-53
UniRef50_Q0AB97 tRNA guanosine-2'-O-methyltransferase n=2 Tax=Ec...   210   3e-53
UniRef50_Q1N3Z0 Putative tRNA/rRNA methyltransferase n=1 Tax=Ber...   208   1e-52
UniRef50_A1U493 tRNA guanosine-2'-O-methyltransferase n=3 Tax=Ga...   206   7e-52
UniRef50_A4SEW2 tRNA guanosine-2'-O-methyltransferase n=10 Tax=C...   204   2e-51
UniRef50_C5BJC4 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Ga...   201   2e-50
UniRef50_Q7TV55 tRNA/rRNA methyltransferase (SpoU) n=34 Tax=cell...   192   6e-48
UniRef50_O67577 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Ba...   164   3e-39
UniRef50_A4BEK2 Putative tRNA methyltransferase n=1 Tax=Reinekea...   162   7e-39
UniRef50_B8IYB0 tRNA guanosine-2'-O-methyltransferase n=14 Tax=D...   160   4e-38
UniRef50_B9L1B3 tRNA guanosine-2'-O-methyltransferase n=3 Tax=Ba...   159   9e-38
UniRef50_A6Q996 tRNA (Guanosine-2'-O-)-methyltransferase n=2 Tax...   153   4e-36
UniRef50_C7PC85 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Chiti...   135   8e-31
UniRef50_C4L0U6 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Ba...   134   3e-30
UniRef50_C9RX94 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Geoba...   131   1e-29
UniRef50_Q84X80 CR004 protein n=1 Tax=Chlamydomonas reinhardtii ...   131   2e-29
UniRef50_D1U4M7 tRNA guanosine-2'-O-methyltransferase n=1 Tax=De...   129   6e-29
UniRef50_A7HIF7 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Anaer...   118   2e-25
UniRef50_Q6MNP1 Putative RNA methylase n=1 Tax=Bdellovibrio bact...   114   2e-24
UniRef50_B7DP24 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Alicy...   113   5e-24
UniRef50_C8WR00 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Bacil...   109   7e-23
UniRef50_A2U211 SpoU rRNA methylase family protein n=1 Tax=Polar...   108   2e-22
UniRef50_B3RWG3 Putative uncharacterized protein n=1 Tax=Trichop...   105   2e-21
UniRef50_A5F9W1 tRNA/rRNA methyltransferase (SpoU) n=16 Tax=Bact...   104   2e-21
UniRef50_O51081 Putative tRNA/rRNA methyltransferase BB_0052 n=1...   104   3e-21
UniRef50_D0LNM3 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Halia...   103   4e-21
UniRef50_A9S3U1 Predicted protein (Fragment) n=2 Tax=Physcomitre...   102   9e-21
UniRef50_D0MG21 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Rhodo...   102   1e-20
UniRef50_A1QYK2 tRNA (Guanosine-2'-O-)-methyltransferase n=7 Tax...   100   3e-20
UniRef50_Q9LXE4 rRNA methylase-like protein n=11 Tax=Magnoliophy...   100   5e-20
UniRef50_B0MYM4 Putative uncharacterized protein n=1 Tax=Alistip...   100   7e-20
UniRef50_Q14PR4 Putative trna/rrna methyltransferase protein n=1...    99   8e-20
UniRef50_Q112U6 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Oscil...    99   1e-19
UniRef50_C6WZC0 tRNA (Guanosine18-2'-O-)-methyltransferase n=1 T...    95   2e-18
UniRef50_A5IXH9 tRNA/rRNA methyltransferase n=1 Tax=Mycoplasma a...    94   3e-18
UniRef50_A6G083 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Plesi...    94   4e-18
UniRef50_A3HSD9 SpoU protein (SpoU) n=1 Tax=Algoriphagus sp. PR1...    94   4e-18
UniRef50_Q2S465 RRNA methylase n=1 Tax=Salinibacter ruber DSM 13...    94   4e-18
UniRef50_B5GW91 tRNA/rRNA methyltransferase n=1 Tax=Streptomyces...    93   5e-18
UniRef50_B3PM16 SpoU class tRNA/rRNA methyltransferase n=1 Tax=M...    92   1e-17
UniRef50_Q09CR8 RRNA methylase n=2 Tax=Cystobacterineae RepID=Q0...    92   2e-17
UniRef50_C0YTB0 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Chrys...    91   2e-17
UniRef50_A9GR15 tRNA (Guanosine-2'-O-)-methyltransferase n=1 Tax...    91   2e-17
UniRef50_C7NJ34 rRNA methylase n=2 Tax=Micrococcineae RepID=C7NJ...    91   3e-17
UniRef50_A1HPG2 TRNA/rRNA methyltransferase (SpoU) n=1 Tax=Therm...    91   4e-17
UniRef50_B3QM30 RNA methyltransferase, TrmH family, group 3 n=12...    90   5e-17
UniRef50_C2FZ75 Possible tRNA/rRNA methyltransferase n=2 Tax=Sph...    89   1e-16
UniRef50_B0TC37 RNA methyltransferase, trmh family n=1 Tax=Helio...    89   1e-16
UniRef50_C1E8J5 Predicted protein (Fragment) n=3 Tax=Mamiellales...    89   2e-16
UniRef50_Q6FF50 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...    88   2e-16
UniRef50_B5YID5 RNA methyltransferase, TrmH family, group 3 n=1 ...    88   2e-16
UniRef50_C3RMB5 23S rRNA methyltransferase n=5 Tax=Bacteria RepI...    88   2e-16
UniRef50_A6DFW8 SpoU protein n=1 Tax=Lentisphaera araneosa HTCC2...    87   3e-16
UniRef50_A4S6N6 Predicted protein (Fragment) n=1 Tax=Ostreococcu...    87   5e-16
UniRef50_C6X1H8 rRNA methylase n=4 Tax=Bacteroidetes RepID=C6X1H...    87   5e-16
UniRef50_A6LPP3 RNA methyltransferase, TrmH family, group 3 n=35...    87   6e-16
UniRef50_Q5HIE3 Putative trmH family tRNA/rRNA methyltransferase...    86   7e-16
UniRef50_C8P2I4 23S rRNA (Guanosine-2'-O-)-methyltransferase Rlm...    86   8e-16
UniRef50_C9RPE6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Fibro...    86   8e-16
UniRef50_Q5HRM1 Putative trmH family tRNA/rRNA methyltransferase...    86   9e-16
UniRef50_B3ETE6 Putative uncharacterized protein n=1 Tax=Candida...    86   9e-16
UniRef50_Q4A787 TRNA/rRNA methyltransferase n=4 Tax=Mycoplasma R...    86   9e-16
UniRef50_C9KPX8 RNA methyltransferase, TrmH family n=1 Tax=Mitsu...    86   1e-15
UniRef50_Q4L3J1 Putative trmH family tRNA/rRNA methyltransferase...    85   2e-15
UniRef50_B0K5F8 RNA methyltransferase, TrmH family, group 3 n=51...    85   2e-15
UniRef50_A4A281 Putative rRNA methylase n=1 Tax=Blastopirellula ...    85   2e-15
UniRef50_C4V0H0 tRNA/rRNA methyltransferase n=1 Tax=Selenomonas ...    84   4e-15
UniRef50_C8WTZ2 RNA methyltransferase, TrmH family, group 3 n=2 ...    84   5e-15
UniRef50_Q06753 Putative trmH family tRNA/rRNA methyltransferase...    83   9e-15
UniRef50_C0Z9E4 Putative RNA methyltransferase n=1 Tax=Brevibaci...    83   9e-15
UniRef50_B2A4B9 RNA methyltransferase, TrmH family, group 3 n=1 ...    82   1e-14
UniRef50_Q1G8Z2 TRNA/rRNA methyltransferase n=109 Tax=Bacilli Re...    82   1e-14
UniRef50_UPI0001C31319 RNA methyltransferase, TrmH family, group...    82   1e-14
UniRef50_A6L4B5 tRNA/rRNA methyltransferase n=16 Tax=Bacteroidet...    82   1e-14
UniRef50_D2R0C4 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Pirel...    82   1e-14
UniRef50_Q488I1 RNA methyltransferase, TrmH family n=1 Tax=Colwe...    82   1e-14
UniRef50_D2QM84 RNA methyltransferase, TrmH family, group 3 n=2 ...    82   2e-14
UniRef50_Q724H1 RNA methyltransferase, TrmH family, group 3 n=21...    82   2e-14
UniRef50_C7M4Y5 tRNA/rRNA methyltransferase (SpoU) n=13 Tax=Bact...    82   2e-14
UniRef50_Q8NQN8 rRNA methylases n=1 Tax=Corynebacterium glutamic...    81   2e-14
UniRef50_C2KW83 Possible RNA methyltransferase n=1 Tax=Oribacter...    81   3e-14
UniRef50_C8NJ74 rRNA methylase n=38 Tax=Actinomycetales RepID=C8...    80   4e-14
UniRef50_B8LD75 Predicted protein n=1 Tax=Thalassiosira pseudona...    80   5e-14
UniRef50_C5NV68 RNA methyltransferase, TrmH family, group 3 n=1 ...    80   5e-14
UniRef50_Q1NS81 RNA methyltransferase TrmH, group 3 n=3 Tax=Delt...    79   9e-14
UniRef50_Q1D7V2 RNA methyltransferase, TrmH family, group 3 n=7 ...    79   1e-13
UniRef50_D0B4K6 tRNA/rRNA methyltransferase n=41 Tax=Rhizobiales...    79   1e-13
UniRef50_A3DH38 RNA methyltransferase, TrmH family, group 3 n=14...    78   2e-13
UniRef50_Q7NYX3 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...    78   2e-13
UniRef50_B0P8C0 Putative uncharacterized protein n=2 Tax=Clostri...    78   2e-13
UniRef50_A8RFN1 Putative uncharacterized protein n=2 Tax=Erysipe...    78   3e-13
UniRef50_Q6AJ92 Related to tRNA/rRNA methyltransferase n=1 Tax=D...    78   3e-13
UniRef50_C9RBD1 RNA methyltransferase, TrmH family, group 3 n=1 ...    77   3e-13
UniRef50_C7G6D1 RNA methyltransferase, TrmH family n=5 Tax=Clost...    77   3e-13
UniRef50_C9LMK8 RNA methyltransferase, TrmH family, group 3 n=1 ...    77   4e-13
UniRef50_B1I0T3 RNA methyltransferase, TrmH family, group 3 n=2 ...    77   4e-13
UniRef50_Q98R32 TRNA/RRNA METHYLTRANSFERASE n=1 Tax=Mycoplasma p...    77   4e-13
UniRef50_B8C0J2 rRNA methyltransferase (Fragment) n=1 Tax=Thalas...    77   4e-13
UniRef50_Q2RFM6 RNA methyltransferase TrmH, group 3 n=2 Tax=Clos...    77   4e-13
UniRef50_A0M5B1 TrmH family tRNA/rRNA methyltransferase n=16 Tax...    77   5e-13
UniRef50_B8G1U5 RNA methyltransferase, TrmH family, group 3 n=4 ...    77   5e-13
UniRef50_D1PXH3 SpoU rRNA methylase n=1 Tax=Prevotella bergensis...    77   6e-13
UniRef50_A8SJQ1 Putative uncharacterized protein n=2 Tax=Parvimo...    77   6e-13
UniRef50_Q8Z0C3 rRNA methylase n=30 Tax=Cyanobacteria RepID=Q8Z0...    77   6e-13
UniRef50_C9A4E5 RNA methyltransferase n=3 Tax=Enterococcus casse...    76   7e-13
UniRef50_Q6MA83 Putative rRNA methylase n=2 Tax=Chlamydiae/Verru...    76   7e-13
UniRef50_B9ZJH8 RNA methyltransferase, TrmH family, group 3 n=1 ...    76   7e-13
UniRef50_Q4A651 Putative tRNA/rRNA methyltransferase n=1 Tax=Myc...    76   9e-13
UniRef50_Q11YB9 tRNA/rRNA methyltransferase, TrmH family n=24 Ta...    76   9e-13
UniRef50_B6YR56 23S rRNA (Guanosine-2'-O-)-methyltransferase n=1...    76   1e-12
UniRef50_Q83CW6 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...    76   1e-12
UniRef50_Q1ISZ4 RNA methyltransferase TrmH, group 3 n=2 Tax=Acid...    76   1e-12
UniRef50_B4U792 RNA methyltransferase, TrmH family, group 3 n=9 ...    75   1e-12
UniRef50_Q9JZR3 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...    75   1e-12
UniRef50_Q7MH13 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...    75   1e-12
UniRef50_A0LZG1 TrmH family tRNA/rRNA methyltransferase n=7 Tax=...    75   1e-12
UniRef50_C4G1K9 Putative uncharacterized protein n=1 Tax=Abiotro...    75   1e-12
UniRef50_Q2ST10 RNA methyltransferase, TrmH family, group 3 n=5 ...    75   1e-12
UniRef50_Q73MR5 RNA methyltransferase, TrmH family, group 3 n=1 ...    75   2e-12
UniRef50_D1CEQ6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Therm...    75   2e-12
UniRef50_A9BJB6 RNA methyltransferase, TrmH family, group 3 n=3 ...    75   2e-12
UniRef50_B2V596 RNA methyltransferase, TrmH family n=7 Tax=Clost...    75   2e-12
UniRef50_A2U0X8 SpoU rRNA methylase family protein n=2 Tax=Polar...    75   3e-12
UniRef50_Q82XD1 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...    74   3e-12
UniRef50_Q2JI19 RNA methyltransferase, TrmH family, group 3 n=2 ...    74   3e-12
UniRef50_C0BJH2 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Flavo...    74   3e-12
UniRef50_A5UYW3 RNA methyltransferase, TrmH family, group 3 n=4 ...    74   3e-12
UniRef50_Q1LSR1 RNA methyltransferase, TrmH family, group 3 n=4 ...    74   3e-12
UniRef50_D0NTV0 SpoU rRNA Methylase family n=17 Tax=Phytophthora...    74   3e-12
UniRef50_A8S2F6 Putative uncharacterized protein n=8 Tax=Clostri...    74   4e-12
UniRef50_B8D0A6 RNA methyltransferase n=11 Tax=Firmicutes RepID=...    74   4e-12
UniRef50_B1AIB3 RNA methyltransferase, TrmH family, group 3 n=15...    74   4e-12
UniRef50_C6CVT7 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Bacil...    74   4e-12
UniRef50_C4Z380 RNA methyltransferase, TrmH family n=1 Tax=Eubac...    74   4e-12
UniRef50_Q2JVF6 RNA methyltransferase, TrmH family n=2 Tax=Synec...    74   4e-12
UniRef50_B0VI64 Putative tRNA/rRNA methyltransferase n=1 Tax=Can...    74   4e-12
UniRef50_A4GI27 rRNA methyltransferase n=1 Tax=uncultured marine...    74   5e-12
UniRef50_B1I4I6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Candi...    74   5e-12
UniRef50_C4V3B4 TrmH family rRNA methyltransferase n=2 Tax=Selen...    74   6e-12
UniRef50_B5JMU7 RNA methyltransferase, TrmH family n=1 Tax=Verru...    73   6e-12
UniRef50_C1F8Y2 RNA methyltransferase, TrmH family, group 3 n=1 ...    73   6e-12
UniRef50_C7H9L6 RNA methyltransferase, TrmH family, group 3 n=3 ...    73   8e-12
UniRef50_D0JB44 tRNA/rRNA methyltransferase n=2 Tax=Blattabacter...    73   8e-12
UniRef50_B0K3L2 tRNA/rRNA methyltransferase (SpoU) n=11 Tax=Ther...    73   9e-12
UniRef50_Q0BY95 RNA methyltransferase, TrmH family n=1 Tax=Hypho...    72   1e-11
UniRef50_C1F3I9 RNA methyltransferase, TrmH family protein n=1 T...    72   1e-11
UniRef50_B5EQA2 RNA methyltransferase, TrmH family, group 3 n=3 ...    72   1e-11
UniRef50_B8HJN1 RNA methyltransferase, TrmH family, group 3 n=6 ...    72   1e-11
UniRef50_Q11C30 tRNA/rRNA methyltransferase (SpoU) n=21 Tax=Alph...    72   1e-11
UniRef50_Q7VQP0 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...    72   1e-11
UniRef50_D1AKE9 tRNA/rRNA methyltransferase (SpoU) n=17 Tax=Fuso...    72   1e-11
UniRef50_Q0AUG1 Conserved hypothetical tRNA/rRNA methyltransfera...    72   1e-11
UniRef50_Q1IND6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Candi...    72   1e-11
UniRef50_D2RLA3 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Acida...    72   1e-11
UniRef50_Q31FJ2 RNA methyltransferase TrmH, group 3 n=1 Tax=Thio...    72   2e-11
UniRef50_C0GIN0 RNA methyltransferase, TrmH family, group 3 n=1 ...    72   2e-11
UniRef50_C4ZGM4 RNA methyltransferase, TrmH family, group 3 n=8 ...    72   2e-11
UniRef50_Q606P1 RNA methyltransferase, TrmH family, group 3 n=1 ...    72   2e-11
UniRef50_B1X411 tRNA/rRNA methyltransferase (SpoU):RNA methyltra...    72   2e-11
UniRef50_B8I1W5 RNA methyltransferase, TrmH family, group 3 n=5 ...    72   2e-11
UniRef50_D1CFS4 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Therm...    71   3e-11
UniRef50_B2S257 Possible rRNA methylase n=3 Tax=Treponema RepID=...    71   3e-11
UniRef50_Q7MBB6 tRNA/rRNA methyltransferase n=1 Tax=Gloeobacter ...    71   3e-11
UniRef50_A6KZH0 tRNA/rRNA methyltransferase n=10 Tax=Bacteroidal...    71   3e-11
UniRef50_A6P2D0 Putative uncharacterized protein n=1 Tax=Bactero...    71   3e-11
UniRef50_Q7NAH8 SpoU n=2 Tax=Mycoplasma RepID=Q7NAH8_MYCGA             71   3e-11
UniRef50_C1ZH70 rRNA methylase, putative, group 3 n=1 Tax=Planct...    71   3e-11
UniRef50_C0X8M7 RNA methyltransferase n=36 Tax=Enterococcus RepI...    71   3e-11
UniRef50_A9AZL1 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Herpe...    71   4e-11
UniRef50_D2R809 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Pirel...    70   4e-11
UniRef50_A4XJ85 RNA methyltransferase, TrmH family, group 3 n=2 ...    70   4e-11
UniRef50_B4WGZ3 RNA methyltransferase, TrmH family n=5 Tax=Bacte...    70   5e-11
UniRef50_D1J7J9 tRNA/rRNA methyltransferase n=2 Tax=Mycoplasma R...    70   5e-11
UniRef50_A2U3D3 SpoU rRNA methylase n=2 Tax=Flavobacteriaceae Re...    70   5e-11
UniRef50_B5YIM1 RNA methyltransferase, TrmH family n=1 Tax=Therm...    70   5e-11
UniRef50_D1R5P1 Putative uncharacterized protein n=1 Tax=Parachl...    70   6e-11
UniRef50_Q88DE7 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...    70   6e-11
UniRef50_P74261 Uncharacterized tRNA/rRNA methyltransferase slr1...    70   6e-11
UniRef50_D2NQI2 rRNA methylase n=54 Tax=Actinomycetales RepID=D2...    70   7e-11
UniRef50_D0LZ96 RNA methyltransferase, TrmH family, group 3 n=1 ...    70   7e-11
UniRef50_C8NEH0 TrmH family RNA methyltransferase n=2 Tax=Granul...    70   8e-11
UniRef50_Q03G93 rRNA methylase n=1 Tax=Pediococcus pentosaceus A...    69   8e-11
UniRef50_Q8EPH3 rRNA methylase n=1 Tax=Oceanobacillus iheyensis ...    69   8e-11
UniRef50_Q6MMA4 Putative tRNA/rRNA methyltransferase n=1 Tax=Bde...    69   1e-10
UniRef50_A0L4P9 RNA methyltransferase, TrmH family, group 3 n=1 ...    69   1e-10
UniRef50_B2UR21 RNA methyltransferase, TrmH family, group 3 n=3 ...    69   1e-10
UniRef50_Q8DNE3 Possible rRNA/tRNA methylase n=69 Tax=Streptococ...    69   1e-10
UniRef50_A1AWI4 RNA methyltransferase, TrmH family, group 3 n=3 ...    69   1e-10
UniRef50_A8DJH5 TsnR n=1 Tax=Candidatus Chloracidobacterium ther...    69   1e-10
UniRef50_Q0VMF8 RNA methyltransferase, TrmH family, group 3 n=2 ...    69   1e-10
UniRef50_B5YF75 RNA methyltransferase, TrmH family, group 3 n=2 ...    69   1e-10
UniRef50_C6X309 RNA methylase, SpoU family n=1 Tax=Flavobacteria...    69   1e-10
UniRef50_Q7P601 23S rRNA methyltransferase n=10 Tax=Fusobacteriu...    69   1e-10
UniRef50_Q2LQ81 23S rRNA Gm2251 methyltransferase n=1 Tax=Syntro...    69   2e-10
UniRef50_B4WGA5 RNA methyltransferase, TrmH family, group 3, put...    69   2e-10
UniRef50_C2BF70 tRNA/rRNA methyltransferase n=1 Tax=Anaerococcus...    69   2e-10
UniRef50_B1M5G3 RNA methyltransferase, TrmH family, group 3 n=16...    69   2e-10
UniRef50_B9KZB6 Possible 23S rRNA methyltransferase tsnR n=1 Tax...    69   2e-10
UniRef50_C6VPS4 rRNA methylase n=8 Tax=Lactobacillales RepID=C6V...    68   2e-10
UniRef50_B4W7H0 RNA methyltransferase, TrmH family n=1 Tax=Brevu...    68   2e-10
UniRef50_A6DS75 tRNA/rRNA methyltransferase n=1 Tax=Lentisphaera...    68   2e-10
UniRef50_Q3AXD9 RNA methyltransferase TrmH, group 3 n=19 Tax=Bac...    68   2e-10
UniRef50_C6QC90 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Hypho...    68   2e-10
UniRef50_B9KYY7 RNA methyltransferase, TrmH family, group 3 n=4 ...    68   2e-10
UniRef50_B8FEV3 RNA methyltransferase, TrmH family, group 3 n=1 ...    68   2e-10
UniRef50_A6BKK3 Putative uncharacterized protein n=6 Tax=Bacteri...    68   2e-10
UniRef50_D2MNZ0 RNA methyltransferase, TrmH family n=1 Tax=Bulle...    68   3e-10
UniRef50_D1NAJ1 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Victi...    68   3e-10
UniRef50_A9KHD7 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Clost...    68   3e-10
UniRef50_P94538 Uncharacterized tRNA/rRNA methyltransferase ysgA...    68   3e-10
UniRef50_B1ZVF9 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Opitu...    68   3e-10
UniRef50_D1A2Z2 tRNA/rRNA methyltransferase (SpoU) n=3 Tax=Strep...    68   3e-10
UniRef50_A9WFI1 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Chlor...    68   3e-10
UniRef50_Q027Q7 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Acido...    68   3e-10
UniRef50_A7HLT3 RNA methyltransferase, TrmH family, group 3 n=2 ...    68   3e-10
UniRef50_C5WEU6 23S rRNA methyltransferase n=2 Tax=Firmicutes Re...    67   3e-10
UniRef50_A9GVZ1 tRNA/rRNA methyltransferase n=1 Tax=Sorangium ce...    67   3e-10
UniRef50_B8D292 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Halot...    67   4e-10
UniRef50_Q67QG1 rRNA methyltransferase n=1 Tax=Symbiobacterium t...    67   4e-10
UniRef50_A8MI79 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Clost...    67   4e-10
UniRef50_A0NWK7 TRNA/rRNA metyltransferase n=1 Tax=Labrenzia agg...    67   5e-10
UniRef50_B0S1P7 23S rRNA methyltransferase n=2 Tax=Finegoldia ma...    67   5e-10
UniRef50_C0QAQ0 SpoU n=1 Tax=Desulfobacterium autotrophicum HRM2...    67   5e-10
UniRef50_D1AP92 RNA methyltransferase, TrmH family, group 3 n=7 ...    67   5e-10
UniRef50_A8PMQ1 RNA methyltransferase, TrmH family, group 3 n=1 ...    67   5e-10
UniRef50_UPI0001BC4585 23S rRNA methyltransferase n=1 Tax=Fusoba...    67   6e-10
UniRef50_A3ZYD4 RNA methyltransferase, TrmH family protein n=3 T...    67   6e-10
UniRef50_Q6ME25 Putative tRNA (Guanosine-2'-O-)-methyltransferas...    67   7e-10
UniRef50_Q2S2J6 RNA methyltransferase, TrmH family, group 3 n=2 ...    67   7e-10
UniRef50_Q0EVP7 RNA methyltransferase, TrmH family, group 3 n=1 ...    67   7e-10
UniRef50_C6HZU7 TRNA/rRNA methyltransferase (SpoU) n=1 Tax=Lepto...    66   7e-10
UniRef50_Q1IWR8 RNA methyltransferase TrmH, group 3 n=6 Tax=Dein...    66   8e-10
UniRef50_C5QRV0 TrmH family rRNA methyltransferase n=3 Tax=Bacil...    66   8e-10
UniRef50_B5CKU5 Putative uncharacterized protein n=1 Tax=Ruminoc...    66   8e-10
UniRef50_Q1J4P0 23S rRNA Gm2251 methyltransferase n=42 Tax=Lacto...    66   8e-10
UniRef50_D0JBH4 SpoU rRNA methylase family protein n=2 Tax=Blatt...    66   8e-10
UniRef50_P74328 Uncharacterized tRNA/rRNA methyltransferase slr0...    66   9e-10
UniRef50_B3L269 SpoU rRNA Methylase, putative n=3 Tax=Plasmodium...    66   9e-10
UniRef50_C4ZPQ7 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Thaue...    66   1e-09
UniRef50_A7B5E9 Putative uncharacterized protein n=7 Tax=Bacteri...    65   1e-09
UniRef50_A2C1X9 RNA methyltransferase TrmH, group 3 n=6 Tax=Cyan...    65   1e-09
UniRef50_A6CBV4 YacO n=1 Tax=Planctomyces maris DSM 8797 RepID=A...    65   1e-09
UniRef50_C9XLS4 Putative RNA methylase n=9 Tax=Clostridium RepID...    65   1e-09

>UniRef50_P0AGJ3 tRNA guanosine-2'-O-methyltransferase n=231 Tax=Bacteria
           RepID=TRMH_ECO57
          Length = 229

 Score =  477 bits (1227), Expect = e-133,   Method: Compositional matrix adjust.
 Identities = 229/229 (100%), Positives = 229/229 (100%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM
Sbjct: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
           ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ
Sbjct: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE
Sbjct: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQAAG 229
           AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQAAG
Sbjct: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQAAG 229


>UniRef50_Q15Z06 tRNA (Guanosine-2'-O-)-methyltransferase n=2 Tax=Pseudoalteromonas
           atlantica T6c RepID=Q15Z06_PSEA6
          Length = 256

 Score =  289 bits (740), Expect = 4e-77,   Method: Compositional matrix adjust.
 Identities = 135/227 (59%), Positives = 178/227 (78%), Gaps = 5/227 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M+  RY RI ++L+ RQP LTVC+EQVHKPHNVSA++R+ DAVG++ +H VW   + +  
Sbjct: 7   MSVERYQRIRKLLSTRQPSLTVCLEQVHKPHNVSAVLRSCDAVGINRIHGVWD-QKTKIR 65

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A GS  WV+ + H +IGDAV+ LK Q MQ+L THLSD++VDFR+IDYT+PT I++GQ
Sbjct: 66  KGTAMGSEHWVKTEMHTSIGDAVSVLKQQNMQVLVTHLSDDSVDFRDIDYTQPTAIILGQ 125

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSM-LP 179
           EK G T+EA+A+AD++I+IPM+GMVQSLNVSVA+A++LYEAQRQR+ AGMY   NS+ L 
Sbjct: 126 EKHGATEEAIAVADKNIVIPMVGMVQSLNVSVAAAVVLYEAQRQREVAGMY---NSLQLS 182

Query: 180 EAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQ 226
           E E QR+LFEGG+PVL+ V + KGL YPH+++ G I ADA WW  MQ
Sbjct: 183 EEECQRVLFEGGFPVLSNVCRNKGLDYPHIDEGGNIVADASWWQKMQ 229


>UniRef50_B5JS83 tRNA (Guanosine-2-O)-methyltransferase n=3 Tax=Bacteria
           RepID=B5JS83_9GAMM
          Length = 225

 Score =  237 bits (605), Expect = 2e-61,   Method: Compositional matrix adjust.
 Identities = 114/213 (53%), Positives = 147/213 (69%), Gaps = 2/213 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M+P R+ R  + L RRQ  LTV ME VHKPHN SAI+R+ +AVGVH  HAV+P   +   
Sbjct: 1   MSPERHQRFIDTLKRRQTSLTVVMENVHKPHNFSAIVRSCEAVGVHRAHAVYPEGGIGNN 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
           A    G++ WVQV THR I      LK QG Q+L  HL + AVDFRE+DYT+PT ++MG 
Sbjct: 61  AGTTVGAHKWVQVDTHRNIQTPFQQLKAQGFQLLTAHLDETAVDFREVDYTQPTAVVMGS 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E  GI++EA  LAD  I+IPM+G+ +SLNVSVA+ALIL+EAQRQRQ AGMY  E   L E
Sbjct: 121 ELHGISEEAAQLADHSIVIPMLGLTESLNVSVATALILFEAQRQRQLAGMY--EQPELDE 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQG 213
           A ++ L+FE  YP LA+  + +G PYP ++ +G
Sbjct: 179 ATRKTLMFEWAYPDLARRYQSRGEPYPELDDEG 211


>UniRef50_C7R944 tRNA guanosine-2'-O-methyltransferase n=1 Tax=Kangiella koreensis
           DSM 16069 RepID=C7R944_KANKD
          Length = 231

 Score =  236 bits (601), Expect = 6e-61,   Method: Compositional matrix adjust.
 Identities = 110/220 (50%), Positives = 152/220 (69%), Gaps = 3/220 (1%)

Query: 2   NPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA 61
           +P R  +I  +L+ RQPDLTV M+QVHKPHN++AI+RTADAVG+  VHAV+P     T  
Sbjct: 5   SPARLQKILTLLSNRQPDLTVFMDQVHKPHNLAAIVRTADAVGIGHVHAVFPEDVKFTGH 64

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
             ++GS  WV    H  +   +A +K +GMQ+LA H SD AVDFR IDYT+PTC+L+G E
Sbjct: 65  HTSSGSKRWVTTHKHSNLKSGIAEMKAKGMQVLAAHFSDTAVDFRTIDYTQPTCLLVGSE 124

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEA 181
             G++ EA  +ADQ +IIPM+GMVQSLNVSVA+ALILYEAQRQR +A MY      +P+A
Sbjct: 125 LVGVSDEAAEIADQHVIIPMVGMVQSLNVSVATALILYEAQRQRSDAEMY--GECKIPQA 182

Query: 182 EQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADW 221
           E   + F+  +P + +   +  + YP +++ G+I+ D +W
Sbjct: 183 EVDEICFKALHPTITRFCDKHKIRYPKMDEFGDID-DPEW 221


>UniRef50_Q0VRD7 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Alcanivorax
           RepID=Q0VRD7_ALCBS
          Length = 230

 Score =  234 bits (597), Expect = 2e-60,   Method: Compositional matrix adjust.
 Identities = 110/226 (48%), Positives = 154/226 (68%), Gaps = 2/226 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M P RY RIC+ L RRQPDLTV M+ VHKPHN++AI+RT DAVG+ +VHAV P +R R  
Sbjct: 1   MTPERYRRICDTLDRRQPDLTVIMDGVHKPHNIAAIVRTCDAVGILDVHAVLPKNRARMA 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
           A  A GS  WVQV       D +  L+GQG+Q+LA HLSD+A+++R++DYTRPT +L+G 
Sbjct: 61  AGTAMGSQRWVQVHKRDESTDVIRELQGQGVQVLAAHLSDDAIEYRQVDYTRPTALLLGT 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G++ E  +  DQ++ IPM+GMV+S NVSVA+A+IL EA  QR+  G Y  +   +  
Sbjct: 121 EKFGVSDEVASAVDQNVTIPMMGMVESFNVSVAAAIILSEACEQRRAKGFY--DQPRVAA 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQ 226
           A    LLF  GY  +A++    G+PYP ++++G+++  A   A +Q
Sbjct: 179 ARYHELLFRWGYARIARLCDAHGVPYPELDEEGQVKDSAALTALLQ 224


>UniRef50_A3IM41 RRNA methylase SpoU n=1 Tax=Cyanothece sp. CCY0110
           RepID=A3IM41_9CHRO
          Length = 220

 Score =  219 bits (557), Expect = 7e-56,   Method: Compositional matrix adjust.
 Identities = 106/213 (49%), Positives = 142/213 (66%), Gaps = 2/213 (0%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMAS 62
           P RY RI ++L +RQPDLT+  E VHKPHN+SAIIRT DAVG+ +VH +       T + 
Sbjct: 5   PRRYHRIRQVLEKRQPDLTILTEDVHKPHNLSAIIRTCDAVGILDVHCINTTDEFPTFSQ 64

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
            + GS+ WV + +H  I   + HLK Q   I A H +D ++D+REIDYT+PT IL+G EK
Sbjct: 65  VSQGSDKWVFLHSHPNIKTGINHLKRQNFNIYAAHFTDQSLDYREIDYTQPTAILLGAEK 124

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAE 182
            G+++EA  L D  II+PM+GMVQSLNVSVA+A+IL+EAQRQR    MY  + S L    
Sbjct: 125 WGVSEEAANLVDGHIIVPMLGMVQSLNVSVAAAVILFEAQRQRLAQKMY--DTSRLDLDR 182

Query: 183 QQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEI 215
             ++LFE  YP LA + ++KG  YP + + G I
Sbjct: 183 YHKILFEWSYPALATIYQKKGENYPSLGKNGVI 215


>UniRef50_C1XS02 rRNA methylase n=2 Tax=Bacteria RepID=C1XS02_9DEIN
          Length = 228

 Score =  218 bits (556), Expect = 1e-55,   Method: Compositional matrix adjust.
 Identities = 114/224 (50%), Positives = 150/224 (66%), Gaps = 12/224 (5%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR---- 56
           M P R+ +I ++LARRQPDLTV ME+VHK HN SA++R+ DAVGV E H + P +     
Sbjct: 1   MTPERWQKIQQVLARRQPDLTVLMERVHKWHNFSAVLRSCDAVGVLEAHLI-PAAHGIPT 59

Query: 57  -----MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYT 111
                 R  A+ +  +  WV ++T+     A A L+ +G  I A H S  A+D+RE+DYT
Sbjct: 60  EDQNPSRHTAATSGSAAKWVGLRTYPDTPSAFADLRSRGFVIYAAHFSHKAIDYREVDYT 119

Query: 112 RPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMY 171
           RPTCIL+G EK G+T+EA  LAD  I+IPM+GMVQSLNVSVA+A+IL+EAQRQR  AGMY
Sbjct: 120 RPTCILLGTEKWGVTEEAATLADGHIVIPMMGMVQSLNVSVAAAVILFEAQRQRIQAGMY 179

Query: 172 LRENSMLPEAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEI 215
            R    L  A  QRLLFE  YP  A+  +++G  YP ++ +GEI
Sbjct: 180 DRPR--LEPALHQRLLFEWAYPDWAERCRKEGRDYPALSPEGEI 221


>UniRef50_B3QXG6 tRNA guanosine-2'-O-methyltransferase n=1 Tax=Chloroherpeton
           thalassium ATCC 35110 RepID=B3QXG6_CHLT3
          Length = 219

 Score =  210 bits (535), Expect = 3e-53,   Method: Compositional matrix adjust.
 Identities = 102/211 (48%), Positives = 142/211 (67%), Gaps = 2/211 (0%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA 64
           R+ +I  +L +RQPDLTV ME V+K HN++AIIRT DAVG+ +VHAV     +RT  ++A
Sbjct: 8   RFQQIKRLLDKRQPDLTVVMENVNKAHNLAAIIRTCDAVGIPKVHAVALRPEIRTKQNSA 67

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTG 124
           +G+N WV V+ H +  D  + L+  G QI   H S  A DFR +D+T+PT +++G E  G
Sbjct: 68  SGANRWVDVQIHNSTEDVFSTLRQGGFQIFVAHFSPQATDFRAVDFTKPTALVVGAEWEG 127

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAEQQ 184
           I++ A++LAD  + +PM+GMV+SLNVSVA+A++L+EAQRQR   G Y  +   L EA  Q
Sbjct: 128 ISETAISLADGSLYVPMVGMVESLNVSVATAIMLFEAQRQRTEKGFY--DKPRLDEATYQ 185

Query: 185 RLLFEGGYPVLAKVAKRKGLPYPHVNQQGEI 215
           RLLFE  YP +A   K+K    P +N  GEI
Sbjct: 186 RLLFELTYPQIATAYKQKDKALPKMNMDGEI 216


>UniRef50_Q0AB97 tRNA guanosine-2'-O-methyltransferase n=2
           Tax=Ectothiorhodospiraceae RepID=Q0AB97_ALHEH
          Length = 220

 Score =  210 bits (534), Expect = 3e-53,   Method: Compositional matrix adjust.
 Identities = 105/215 (48%), Positives = 147/215 (68%), Gaps = 2/215 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M   R  R+ + L RRQPDL V ++QVHKPHN+SAI+RT DAVGV   HAV         
Sbjct: 1   MTARRLHRMRQTLERRQPDLQVLLDQVHKPHNLSAILRTCDAVGVPRAHAVSRHQDFTVH 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
            +A++G+  WV V+TH  +  AV  ++GQGM++ A HLS+ AVD+R++DYT+P C+L+G 
Sbjct: 61  RAASSGTGQWVAVETHADLPAAVRAVQGQGMKVYAAHLSEQAVDYRQVDYTKPCCLLLGA 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G+++E  ALAD  +IIPM G+  SLNVSVA+A+IL+EAQRQR  AG Y  E   + E
Sbjct: 121 EKEGVSEEGAALADGHVIIPMFGLGASLNVSVAAAVILFEAQRQRLAAGQY--ETPRMAE 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEI 215
           AE  R L E  +P +A+  +++G PYP +++ G +
Sbjct: 179 AEITRTLVEWLHPRIAERCRKEGRPYPALDEDGGV 213


>UniRef50_Q1N3Z0 Putative tRNA/rRNA methyltransferase n=1 Tax=Bermanella marisrubri
           RepID=Q1N3Z0_9GAMM
          Length = 229

 Score =  208 bits (530), Expect = 1e-52,   Method: Compositional matrix adjust.
 Identities = 106/215 (49%), Positives = 140/215 (65%), Gaps = 2/215 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M P R  R+ ++L +RQPDLT+  + V KPHN+SAIIR+ DA  V+E++ VWP    +T 
Sbjct: 1   MTPERVQRMHDILRKRQPDLTLITDAVFKPHNLSAIIRSCDAFAVNELNVVWPYDDYQTF 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A GS  +V VKTH+ +  A+   K QG QI+A H  D AV   +IDYT+PT I+MG 
Sbjct: 61  RGRAMGSQQYVNVKTHKDVSQAIQGFKQQGYQIVAAHFCDQAVPHYDIDYTKPTAIVMGA 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G++ +A+ L D  II+PM GMVQSLNVSVA+ALIL EA  QR+N GM L EN +  E
Sbjct: 121 EKNGVSAKAMDLVDHSIIVPMEGMVQSLNVSVAAALILSEAMHQRKNKGM-LGENQLDSE 179

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEI 215
             Q +  FE  YP LAK  K+ G+ YP + + G+ 
Sbjct: 180 TYQIQ-FFEWCYPDLAKRCKKLGMAYPKLKENGDF 213


>UniRef50_A1U493 tRNA guanosine-2'-O-methyltransferase n=3 Tax=Gammaproteobacteria
           RepID=A1U493_MARAV
          Length = 244

 Score =  206 bits (523), Expect = 7e-52,   Method: Compositional matrix adjust.
 Identities = 105/222 (47%), Positives = 137/222 (61%), Gaps = 3/222 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M P R ARI ++L  RQPDL V  +QVHKP N+SAIIR+ DA G+  +H VWP    R  
Sbjct: 1   MTPERLARIKQVLNTRQPDLRVLTDQVHKPRNLSAIIRSCDAFGLANMHVVWPKEGFRAF 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A GS  WV   TH T+ +AV  LK QG ++ A  LSD AVDFRE+DYT P  I+MG 
Sbjct: 61  RKTAGGSFHWVTTHTHPTMDNAVTELKAQGHKLYAAQLSDRAVDFREVDYTVPCTIIMGN 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E  G+       AD+ I+IPM+GMV+SLNVS A ++IL EAQRQR+ AGM+  +   +P+
Sbjct: 121 EVDGVNPVTAEQADEHIVIPMMGMVESLNVSSACSIILSEAQRQRKLAGMF--DQRRMPD 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQ-GEIEADADW 221
            E  RLLF    P + +    + LPYP ++ + GE+     W
Sbjct: 179 DEYNRLLFCWCQPTVKRYCDDRNLPYPPIDHETGELIDGVGW 220


>UniRef50_A4SEW2 tRNA guanosine-2'-O-methyltransferase n=10 Tax=Chlorobiaceae
           RepID=A4SEW2_PROVI
          Length = 232

 Score =  204 bits (519), Expect = 2e-51,   Method: Compositional matrix adjust.
 Identities = 103/213 (48%), Positives = 142/213 (66%), Gaps = 2/213 (0%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMAS 62
           P R+ RI +MLA RQPDLTV M+ V+KPHN+SAIIR+ DAVG+H+++AV     + T  +
Sbjct: 4   PERFLRIKKMLASRQPDLTVVMDNVNKPHNLSAIIRSCDAVGIHDLYAVSSKKSIHTTQN 63

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
           AAAG+  W  +   + IG     L  +GMQ+LA   ++ + DFR ID+T PT I++G E 
Sbjct: 64  AAAGAGRWTNLHLRKDIGTLCRKLGMEGMQVLAATNTEESRDFRTIDFTLPTAIVLGAEW 123

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAE 182
            G++ EA+  AD  I IPM GMV+SLNVSVA+ALIL+EA+RQR   GMY      L E+ 
Sbjct: 124 EGVSAEAIQAADMAITIPMYGMVESLNVSVAAALILFEAERQRSLKGMY--RTRRLEESL 181

Query: 183 QQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEI 215
            ++LLFE  YP L++  + KG  YP +++ G I
Sbjct: 182 YRKLLFELSYPRLSRQLREKGGAYPELDEDGGI 214


>UniRef50_C5BJC4 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Gammaproteobacteria
           RepID=C5BJC4_TERTT
          Length = 228

 Score =  201 bits (510), Expect = 2e-50,   Method: Compositional matrix adjust.
 Identities = 98/227 (43%), Positives = 142/227 (62%), Gaps = 2/227 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M P R+ RI  +L +RQPDLTV  ++VHK  N+SAI RT DAVG+  +H V P    +T 
Sbjct: 1   MTPERFQRITSVLNKRQPDLTVITDEVHKGRNLSAITRTCDAVGIDTIHCVMPEDGYQTY 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              +A +  WV V+ H +I   V  LK +G Q++A +L DN +D+R +DYT+PT +++G 
Sbjct: 61  NGTSASAEKWVAVQHHSSISAPVNDLKREGFQLVAANLGDNTLDYRNVDYTKPTALVLGA 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E  G++ EA A  D ++ +PM+GMV+S NVSVA+A+IL EAQ QRQ AG+Y  +   L  
Sbjct: 121 EVKGVSPEAAAAVDYNVTVPMVGMVESFNVSVAAAIILMEAQHQRQQAGLY--DQPRLTA 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQA 227
              +   F   +PVLAK     G+ YP V + GE++  + W++  QA
Sbjct: 179 DVYRARFFHWAHPVLAKWCDDNGVEYPPVREDGEVKNLSAWYSAEQA 225


>UniRef50_Q7TV55 tRNA/rRNA methyltransferase (SpoU) n=34 Tax=cellular organisms
           RepID=Q7TV55_PROMM
          Length = 245

 Score =  192 bits (489), Expect = 6e-48,   Method: Compositional matrix adjust.
 Identities = 100/215 (46%), Positives = 136/215 (63%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMAS 62
           P R+ R+  +L  R  DLTV +E V KPHN+SAI+R+ DAVGV E HAV    R+ T  S
Sbjct: 21  PRRFDRLKAVLDCRMADLTVLLEHVEKPHNLSAILRSCDAVGVLEAHAVNYSGRLPTFNS 80

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
            A GS  W+ +K H +I  AV  +K  G ++  THL  NA D+R+ D+  PT  ++G EK
Sbjct: 81  TAQGSQKWIPLKEHSSIEVAVKAIKDSGFRLYGTHLGGNARDYRDCDFCEPTAFVLGAEK 140

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAE 182
            G+++ A  L D+ I IPM GMVQSLNVSVA+A +L+EA RQR+ AG+  +    L  A 
Sbjct: 141 WGLSKLATPLMDEGIFIPMSGMVQSLNVSVAAATLLFEALRQRRLAGIAPQAGEGLEPAL 200

Query: 183 QQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEA 217
            Q+ LFE  YP +A   +++G  YP +N QGEI+ 
Sbjct: 201 YQQRLFEWAYPEVAAWCQQEGKSYPALNDQGEIQG 235


>UniRef50_O67577 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Bacteria
           RepID=TRMH_AQUAE
          Length = 211

 Score =  164 bits (414), Expect = 3e-39,   Method: Compositional matrix adjust.
 Identities = 88/200 (44%), Positives = 123/200 (61%), Gaps = 7/200 (3%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGV---HEVHAVWPGSRMRTMA 61
           R  R+ E+L +RQ DL V  + V   HN SAI+RT DAVGV   +  HA   G + +   
Sbjct: 11  RLKRLREVLEKRQKDLIVFADNVKNEHNFSAIVRTCDAVGVLYLYYYHA--EGKKAKINE 68

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
               GS+ WV ++        +   K +G QI+AT LS  +V+FRE+DYT+PT +++G E
Sbjct: 69  GITQGSHKWVFIEKVDNPVQKLLEFKNRGFQIVATWLSKESVNFREVDYTKPTVLVVGNE 128

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEA 181
             G++ E + +AD+ I+IPM GM QSLNVSVA+ +ILYEAQRQR+  GMY R +  L E 
Sbjct: 129 LQGVSPEIVEIADKKIVIPMYGMAQSLNVSVATGIILYEAQRQREEKGMYSRPS--LSEE 186

Query: 182 EQQRLLFEGGYPVLAKVAKR 201
           E Q++L +  Y  + K  KR
Sbjct: 187 EIQKILKKWAYEDVIKERKR 206


>UniRef50_A4BEK2 Putative tRNA methyltransferase n=1 Tax=Reinekea blandensis MED297
           RepID=A4BEK2_9GAMM
          Length = 224

 Score =  162 bits (410), Expect = 7e-39,   Method: Compositional matrix adjust.
 Identities = 85/214 (39%), Positives = 128/214 (59%), Gaps = 6/214 (2%)

Query: 4   TRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASA 63
           +RY +  ++L +RQ D+T+  ++VHK  NVSAI+RTAD+VG+  VH V P          
Sbjct: 4   SRYLKFQQVLNQRQNDMTILTDKVHKSQNVSAIMRTADSVGIPTVHMVKPERGRLVYHHT 63

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           A G++ +V V  + T+ + +  L+  GM + A H SD A+ +RE DYTRP  +++G EK 
Sbjct: 64  AGGASRFVDVIVYETLSEGIQSLRNAGMALYAAHWSDRAISYREADYTRPFALILGAEKY 123

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAEQ 183
           GI+ EA   AD+ +IIPM+G  +SLNVSVAS +IL EA  QR     Y    + LP+ + 
Sbjct: 124 GISPEAADAADEHLIIPMVGACESLNVSVASGIILQEAMHQRMAQQAY----TQLPDQDS 179

Query: 184 --QRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEI 215
                LF   +P +A     + LPYP +++ G++
Sbjct: 180 TYHNTLFRWLHPKMAAFCDARQLPYPQLDEDGDM 213


>UniRef50_B8IYB0 tRNA guanosine-2'-O-methyltransferase n=14 Tax=Desulfovibrionales
           RepID=B8IYB0_DESDA
          Length = 250

 Score =  160 bits (404), Expect = 4e-38,   Method: Compositional matrix adjust.
 Identities = 78/168 (46%), Positives = 108/168 (64%), Gaps = 1/168 (0%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA-SA 63
           R AR+ E+LA RQPDLT+ +  +H PHNVSAI R+ DA GV  V+  +  +    +    
Sbjct: 63  RKARLLEVLAHRQPDLTLVLANIHDPHNVSAIYRSCDAFGVSRVNLYYTNTPFPALGRKT 122

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           +A +  WV+   H+     +  L+GQ MQ+LAT  S  A   R+ D+TRPT ++MG E +
Sbjct: 123 SASARKWVESARHKDSAALMESLRGQNMQVLATSCSPTARPLRDWDFTRPTAVIMGNEHS 182

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMY 171
           G+  E L +AD ++ IPM GM+QS NVSVA+A+IL EA RQR+ AGMY
Sbjct: 183 GVEPELLQMADGELYIPMYGMIQSFNVSVAAAIILSEAARQREAAGMY 230


>UniRef50_B9L1B3 tRNA guanosine-2'-O-methyltransferase n=3 Tax=Bacteria
           RepID=B9L1B3_THERP
          Length = 217

 Score =  159 bits (401), Expect = 9e-38,   Method: Compositional matrix adjust.
 Identities = 81/172 (47%), Positives = 114/172 (66%), Gaps = 3/172 (1%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA 64
           R AR+ E+LARRQPDLTV +E VH PHNVSA++R+ DAVG+  VH V+       ++   
Sbjct: 9   RLARMREVLARRQPDLTVVLENVHDPHNVSAVLRSCDAVGLLRVHLVYTLEEFPELSENV 68

Query: 65  AGSN-SWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNA--VDFREIDYTRPTCILMGQE 121
           +GS   W+++  H +I      L+ QG  I  T+L D A  VD  ++D T+P  ++ G E
Sbjct: 69  SGSALKWLELVFHPSIEACYRTLRSQGFTIYTTYLGDPARSVDLYDLDLTKPVALVFGNE 128

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLR 173
           + G++ EA+A AD + +IPM+GMV+SLN+SVA A+ LYEA RQR+ AG Y R
Sbjct: 129 QRGVSDEAVAGADGNFVIPMMGMVRSLNISVACAVSLYEALRQRRLAGHYAR 180


>UniRef50_A6Q996 tRNA (Guanosine-2'-O-)-methyltransferase n=2
           Tax=Epsilonproteobacteria RepID=A6Q996_SULNB
          Length = 216

 Score =  153 bits (387), Expect = 4e-36,   Method: Compositional matrix adjust.
 Identities = 89/206 (43%), Positives = 125/206 (60%), Gaps = 7/206 (3%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR-MRTMASA 63
           R  RI ++L  +QP L V ++ VH   N+SAI+RT DAVGV  ++     +R +R   + 
Sbjct: 13  RIDRIDQILCCKQPTLKVMLDDVHSSQNLSAILRTCDAVGVQHLYYTTSDNRDLRIHKTI 72

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQ--GMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
             G++ WV+     T    V   K Q  G Q++ THL + AV FRE+DYT+PT I+MG E
Sbjct: 73  TQGAHRWVERTRISTEEQRVFLQKKQKEGYQVVVTHLEERAVPFREVDYTKPTIIVMGNE 132

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEA 181
           K G++ E + LAD  IIIPM GMVQSLNVSVA+ALILYEA+RQ   AG Y  +   L + 
Sbjct: 133 KDGVSSETVELADTVIIIPMQGMVQSLNVSVAAALILYEAERQLAEAGKY--DTPQLSKE 190

Query: 182 EQQRLLFEGGYPVLAKVAKRKGLPYP 207
           E++++  + G+     +A+R     P
Sbjct: 191 EREKI--KSGWLYRDNIARRSKGKIP 214


>UniRef50_C7PC85 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Chitinophaga pinensis
           DSM 2588 RepID=C7PC85_CHIPD
          Length = 197

 Score =  135 bits (341), Expect = 8e-31,   Method: Compositional matrix adjust.
 Identities = 70/194 (36%), Positives = 115/194 (59%), Gaps = 4/194 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAV--WPGSRMR 58
           M P R  R+  +L +RQ  LTV +E V  PHN+SA++RT DAVG+ +V+ +      R R
Sbjct: 1   MTPERRERLLSVLNKRQAGLTVVLENVFDPHNISAVLRTCDAVGIQDVYVLNTTTARRKR 60

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
               +++ +  W+ V         +A ++ +  +I  THL+ +A    E+D+T    ++ 
Sbjct: 61  WGHKSSSSAAKWLTVHQFSDTATCMAVVREKYDKIYTTHLAADAKSLYELDFTGSVALVF 120

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSML 178
           G E+ G+++E   L D + IIP +G+++SLN+SVA A+ +YEA RQ+  AG Y ++N  L
Sbjct: 121 GNEQEGVSEEIRKLCDGNFIIPQVGIIKSLNISVACAVSIYEAMRQKSIAGHYEQKN--L 178

Query: 179 PEAEQQRLLFEGGY 192
           P+A+   LL E G+
Sbjct: 179 PDAQYNALLEEWGF 192


>UniRef50_C4L0U6 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Bacillales
           RepID=C4L0U6_EXISA
          Length = 254

 Score =  134 bits (336), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 69/185 (37%), Positives = 110/185 (59%), Gaps = 3/185 (1%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMAS 62
           P R  R+ E+L  R   +T+  E V  PHN SA++R+ADA GV  +H V   ++ +  + 
Sbjct: 41  PDRIKRMYEVLNTRTNHITILTEGVDDPHNQSAVLRSADAFGVQTLHVVEGRAKFKPNSI 100

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
            A  ++ WV V  H +I +A+  LK  G Q+ AT LS+ A+   E+D ++PT +L G E 
Sbjct: 101 IAKSADRWVDVVEHGSIEEAIDALKESGYQVYATALSEEAIPLEEVDVSKPTVLLFGNEH 160

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAE 182
           +G+++ AL  AD + +IPM G VQSLN+SVA+A+ LY+   + ++    + +   LP  +
Sbjct: 161 SGVSETALHKADGNFVIPMQGYVQSLNISVAAAISLYDVTTRSRHI---VTDGYELPVED 217

Query: 183 QQRLL 187
           Q R+ 
Sbjct: 218 QARIF 222


>UniRef50_C9RX94 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Geobacillus
           RepID=C9RX94_GEOSY
          Length = 247

 Score =  131 bits (330), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 74/181 (40%), Positives = 108/181 (59%), Gaps = 10/181 (5%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW---PGSRMRT 59
           P R  R+ E+L  R   +TV +E V  PHN +A++RTA+A GV +VH V    P S  R 
Sbjct: 32  PRRLRRMYEVLNERTRYITVLIEAVDDPHNQAAVLRTAEAFGVQDVHIVTGKAPFSPNRL 91

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
           +   A   + W+ +     I  A+A LK QG Q+ A++L +  +   +ID ++PT +L G
Sbjct: 92  VTRYA---DQWLTLHHKPDIKTAIADLKSQGYQVYASYLGEGTIPVSDIDLSQPTALLFG 148

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYE-AQRQRQNAGMYLRENSML 178
            E +G+++EAL LAD   +IPM G VQS N+SVA+AL LY+  +R R+ AG   R   +L
Sbjct: 149 NEHSGVSEEALRLADGTFVIPMYGFVQSFNISVAAALALYDVTERARRQAG---RHYYLL 205

Query: 179 P 179
           P
Sbjct: 206 P 206


>UniRef50_Q84X80 CR004 protein n=1 Tax=Chlamydomonas reinhardtii RepID=Q84X80_CHLRE
          Length = 316

 Score =  131 bits (329), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 71/162 (43%), Positives = 109/162 (67%), Gaps = 1/162 (0%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS-RMRTMASA 63
           R  RI E++A+R   +   +E ++   N++A+ RTADA+G   VHAV     + +     
Sbjct: 77  RVKRIEEVVAKRTFTVLPIVEGLYDMGNLAAVCRTADALGYGAVHAVNKADGKFKMSQRT 136

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           AAG++ W+ VK   + G+ +A +K  G QI+ THL+ +++  +E+D+TRPT +++G EK 
Sbjct: 137 AAGADKWLDVKAWDSTGECLAAMKAAGYQIVTTHLTQSSITIQEVDWTRPTAVVLGNEKF 196

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           G++ EA+A AD   IIPM GMV+S N+SVA+ALILYEAQ+QR
Sbjct: 197 GVSAEAVAAADACAIIPMTGMVESFNISVANALILYEAQQQR 238


>UniRef50_D1U4M7 tRNA guanosine-2'-O-methyltransferase n=1 Tax=Desulfovibrio
           aespoeensis Aspo-2 RepID=D1U4M7_9DELT
          Length = 226

 Score =  129 bits (325), Expect = 6e-29,   Method: Compositional matrix adjust.
 Identities = 74/178 (41%), Positives = 105/178 (58%), Gaps = 7/178 (3%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           ++  R  RI ++LARRQ DLT+ M+ +  PHNVSA++R+ DA GV +VH  +  S+   +
Sbjct: 25  ISDKRKQRIDQVLARRQKDLTLVMDNIWDPHNVSAVLRSCDAFGVSDVHLYYTTSQWPDL 84

Query: 61  ASAAAGSN-SWVQVKTHRTIGDAVAHL------KGQGMQILATHLSDNAVDFREIDYTRP 113
              ++GS   W+++  H      V +L         G QIL T  S  A    + D+T P
Sbjct: 85  GKKSSGSAMKWIRLIRHVDAATMVGNLVGGGGSAHDGGQILRTGFSATARPVMDFDFTIP 144

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMY 171
           T I++  E  G + E  AL   ++ IPM GMVQSLNVSVA+A+ILYEA  QR+ AG+Y
Sbjct: 145 TAIILSNEHRGTSPELAALVPDEVYIPMQGMVQSLNVSVAAAIILYEAFTQRKRAGLY 202


>UniRef50_A7HIF7 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Anaeromyxobacter
           RepID=A7HIF7_ANADF
          Length = 239

 Score =  118 bits (295), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 64/167 (38%), Positives = 97/167 (58%), Gaps = 7/167 (4%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAV----WPGSRMR 58
           P R ARI  ++A R   LTV ME    P NV+A++RT +A G+ E+H +     P  R +
Sbjct: 28  PERRARIDAVVANRTRTLTVVMEAFCDPQNVNAVLRTCEAFGIQELHVIEGPMKPYDRNK 87

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
            ++  A   + WV V+   + G+ +AHLK +G  I ATHL + A     + +     ++ 
Sbjct: 88  KISQNA---DKWVDVRRWSSTGECLAHLKAEGFAIYATHLGEGARTLDALSFAGKVALVF 144

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           G E  G++ EA+AL+D   +IPM G VQSLNVSVA+A+ + +A  +R
Sbjct: 145 GNEHRGVSDEAVALSDAVYVIPMHGFVQSLNVSVAAAISIAKAVERR 191


>UniRef50_Q6MNP1 Putative RNA methylase n=1 Tax=Bdellovibrio bacteriovorus
           RepID=Q6MNP1_BDEBA
          Length = 238

 Score =  114 bits (286), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 68/184 (36%), Positives = 102/184 (55%), Gaps = 5/184 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           +   R  +I +++A R  D  V +E ++   N+SA++R+A+ +G    H +    + +  
Sbjct: 29  LTDERRQKIEKVVALRNFDTAVVLEGIYDRGNISAVMRSAEGLGFGNFHVIETQEKFKEA 88

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
                G++ WV+VK  +   D V  LK QG +I  THL  NA    EID++  T +++G 
Sbjct: 89  NRVTQGADKWVEVKKWKKTADCVKALKNQGYKIYVTHLDANAKPLHEIDFSGKTALVLGN 148

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR-QNAGMYLRENSMLP 179
           E+ G+T E +A ADQ IIIPM G VQS N+SVA AL LY   + R +  G     N+ L 
Sbjct: 149 ERDGVTPEMIAAADQTIIIPMTGFVQSFNISVAGALGLYHISQDRLKRRGT----NASLT 204

Query: 180 EAEQ 183
           E EQ
Sbjct: 205 EEEQ 208


>UniRef50_B7DP24 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Alicyclobacillus
           acidocaldarius LAA1 RepID=B7DP24_9BACL
          Length = 249

 Score =  113 bits (282), Expect = 5e-24,   Method: Compositional matrix adjust.
 Identities = 63/159 (39%), Positives = 87/159 (54%), Gaps = 1/159 (0%)

Query: 12  MLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWV 71
           +L RR   + V ME V   HN +AI+R+A+A GV  V  +      +       G++ W+
Sbjct: 37  VLMRRTGYIAVAMEAVDDGHNQAAILRSAEAFGVQHVAVIEGKQPFQPSKGVTQGAHKWL 96

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            +    ++G A+  L  +G Q+ AT L D A     +D  RPT IL G EK G++ EA  
Sbjct: 97  TIHRMPSVGRAIDALHARGFQVYATDLGDGAEPIDAVDLARPTAILFGNEKDGVSPEARE 156

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYE-AQRQRQNAG 169
            AD    IPM G VQS NVSVA+A+ LYE  +R R+ AG
Sbjct: 157 RADGRFYIPMAGFVQSFNVSVAAAIALYELTRRARETAG 195


>UniRef50_C8WR00 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Bacillales
           RepID=C8WR00_ALIAD
          Length = 256

 Score =  109 bits (273), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 62/159 (38%), Positives = 85/159 (53%), Gaps = 1/159 (0%)

Query: 12  MLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWV 71
           +L RR   + V ME V   HN +AI+R+A+A GV  V  +              G++ W+
Sbjct: 41  VLMRRTSYIAVAMEAVDDGHNQAAILRSAEAFGVQHVAVIEGKQPFHPSKGVTQGAHKWL 100

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            ++    IG A+  L  +G Q+ AT L + A     +D  RPT IL G EK G++ EA  
Sbjct: 101 TLQRMPDIGRAIDALHARGFQVYATDLGEGAQPIDAVDLARPTAILFGNEKDGVSPEARE 160

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYE-AQRQRQNAG 169
            AD    IPM G VQS NVSVA+A+ LYE  +R R+  G
Sbjct: 161 RADGRFYIPMAGFVQSFNVSVAAAIALYELTRRARETVG 199


>UniRef50_A2U211 SpoU rRNA methylase family protein n=1 Tax=Polaribacter sp. MED152
           RepID=A2U211_9FLAO
          Length = 229

 Score =  108 bits (269), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 61/194 (31%), Positives = 100/194 (51%), Gaps = 8/194 (4%)

Query: 11  EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSW 70
           ++LA R    TV +E +++PHN SA++RT D  GV ++H +      R       G+  W
Sbjct: 28  KVLAERTRHFTVVLEDIYQPHNASAVVRTCDIFGVQDLHVIENRYINRVSKYVTKGAQKW 87

Query: 71  VQVKTHRTIGD----AVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           +  K ++T GD     + HLK  G QI+AT    +A   ++    + T  + G E TGI+
Sbjct: 88  ITTKRYKTDGDNTKTCLNHLKTAGYQIIATSPHADANLLQDFKIDKKTAFVFGAEATGIS 147

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAEQQRL 186
                 AD  + IPM+G  +S N+SVA+A+IL +   + +N+    R + ML   E+++L
Sbjct: 148 DTVKEHADGFLKIPMVGFTESFNISVAAAIILQDVTTRLKNS----RIDWMLSNDEKEQL 203

Query: 187 LFEGGYPVLAKVAK 200
             +     +  V K
Sbjct: 204 YLQWIKETIKNVTK 217


>UniRef50_B3RWG3 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
           RepID=B3RWG3_TRIAD
          Length = 246

 Score =  105 bits (261), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 59/186 (31%), Positives = 97/186 (52%), Gaps = 4/186 (2%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAV-WPGSRMRTMASA 63
           R  ++   +  R   + V +E +    N  AI RT DA+G    H +  P  R++T    
Sbjct: 54  RLDKMTNAVKNRTRSIAVVLEGITNEGNEQAIYRTMDALGFQTAHRIPSPLYRLKTCGRT 113

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
            AG+  W+ +++ ++  + ++ LK  G +ILAT   +        D++  T +++G E+ 
Sbjct: 114 DAGAMKWIDIESWKSTEECISQLKSCGYKILATSSENKTKTLDSFDFSNKTAVVLGSEQE 173

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAEQ 183
           GI++EA+ L D    I M+G V+S NVSVA+A+ILY   + R     Y   +  L EAEQ
Sbjct: 174 GISKEAMNLVDNVFRISMVGFVESYNVSVAAAIILYHIYQDRIRKLGY---HGDLTEAEQ 230

Query: 184 QRLLFE 189
             LL +
Sbjct: 231 DDLLLQ 236


>UniRef50_A5F9W1 tRNA/rRNA methyltransferase (SpoU) n=16 Tax=Bacteroidetes
           RepID=A5F9W1_FLAJ1
          Length = 220

 Score =  104 bits (260), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 48/170 (28%), Positives = 93/170 (54%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           +   R  +  ++L  R    T+ +E V++ HN SA++R+ +  G+ E++ +      R  
Sbjct: 14  LTDNRKEKFLKVLENRTKHFTIAVEDVYQMHNTSAVMRSCEVFGIQELNIIEQRFGKRID 73

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A G+  WV +    T+   ++ L+ +G QI+AT   +N    ++ D ++P+ +  G 
Sbjct: 74  KEIALGAQKWVDINRFDTVDGCISSLRDKGYQIIATTPHENDCLIQDFDISKPSALFFGT 133

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGM 170
           EK G++ E L  AD  + IPM+G  +SLN+SV++A+I+     + +N+ +
Sbjct: 134 EKDGLSPEILEKADGFLKIPMVGFTESLNISVSAAIIIQNLTNRLRNSDI 183


>UniRef50_O51081 Putative tRNA/rRNA methyltransferase BB_0052 n=15 Tax=Borrelia
           RepID=Y052_BORBU
          Length = 218

 Score =  104 bits (259), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 58/181 (32%), Positives = 93/181 (51%), Gaps = 6/181 (3%)

Query: 7   ARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAG 66
           ARI ++L  R   LT  +E + +  N SA IRT + +G+ +VH +   ++         G
Sbjct: 22  ARIEKVLNLRTNYLTFVLEDIFQSQNASATIRTGEILGLSDVHVIEKKNKHTLNPDVTLG 81

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           S+ W+ +  ++    A+  LK  G  I+AT L+  +++   +       I  G E TG++
Sbjct: 82  SSQWINLNKYKNAKFAIDRLKSDGYSIVATSLNPKSINLENLTINNKMAIFFGTELTGLS 141

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYE-AQRQRQNAGMYLRENSMLPEAEQQR 185
            E L  AD  + IPM G  QS N+SVA A+++Y    R R+++  YL     L EAE+  
Sbjct: 142 AEVLGAADLYVKIPMYGFTQSYNISVAVAIVMYSLLMRLRKSSIDYL-----LNEAEKSN 196

Query: 186 L 186
           L
Sbjct: 197 L 197


>UniRef50_D0LNM3 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Haliangium ochraceum DSM
           14365 RepID=D0LNM3_HALO1
          Length = 231

 Score =  103 bits (258), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 56/166 (33%), Positives = 94/166 (56%), Gaps = 2/166 (1%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA 64
           R ARI  +L+ R   LTV +E +H PHN +A++R+ +AVG+  +H   P  R +   + A
Sbjct: 33  RAARIDSVLSARLSGLTVAIENLHDPHNGAAVVRSVEAVGLTSLHVAEPIERFQFSPAVA 92

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTG 124
            GS  W++V  H+        L+G G ++ A    D  +   +ID ++P+ ++ G E  G
Sbjct: 93  IGSEKWIRVLRHQGFTACARILRGAGFRMYAA-CPDAEMSMDDIDVSQPSAVVFGNEHEG 151

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYE-AQRQRQNAG 169
           +++ A+   D  + IPM G  QSLN+SV+ A+ +++ A R+R   G
Sbjct: 152 LSRRAIDACDAKVAIPMHGFTQSLNLSVSVAVSIFQLAARRRALLG 197


>UniRef50_A9S3U1 Predicted protein (Fragment) n=2 Tax=Physcomitrella patens subsp.
           patens RepID=A9S3U1_PHYPA
          Length = 241

 Score =  102 bits (254), Expect = 9e-21,   Method: Compositional matrix adjust.
 Identities = 53/167 (31%), Positives = 92/167 (55%), Gaps = 2/167 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           +   R  RI E++A R   + + +E +    NVSA+ R+ADA+G   VH +   ++ R  
Sbjct: 34  LGDERKQRIEEVVANRTYSICIAVEGLLDLGNVSAVCRSADALGFQSVHVISNETKKRYK 93

Query: 61  AS--AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
            +   + G+  W+  +      D +  L+ +G +I  TH++ + V   ++D+T PT +  
Sbjct: 94  KNRKVSMGTEKWLDAELWSNTSDCIDTLRQRGYRIAVTHIAPDTVSIYDMDWTIPTAVFF 153

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           G E  G ++EA+  +D    IPM GMV+S N+SVA+ +I++ A R R
Sbjct: 154 GNEFMGASEEAIKQSDVRCCIPMAGMVESFNISVAAGIIMHHAARDR 200


>UniRef50_D0MG21 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Rhodothermus marinus DSM
           4252 RepID=D0MG21_RHOM4
          Length = 259

 Score =  102 bits (253), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 60/167 (35%), Positives = 96/167 (57%), Gaps = 4/167 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS--RMR 58
           +   R  RI ++L  R   +   +E +    NVSA++R+A+A+G ++   +  G   + +
Sbjct: 52  LTERRRQRIEQVLDGRTYTVVPVVEGLANTGNVSAVMRSAEALG-YQGFGIIKGQVQKYK 110

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
           T    A G++ W+ V T  T  +AV  LK  G +I+AT L + A      D+T PT ++ 
Sbjct: 111 TSERTAQGADKWLDVWTWPTAAEAVPALKAAGYRIVATAL-EEAEPIDTFDFTVPTALVF 169

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           G E  G+++E LA+AD   +IP++G  QS N+SVA+A+ LY AQR R
Sbjct: 170 GNEVEGVSRELLAMADARCVIPIVGFTQSFNISVAAAIALYHAQRDR 216


>UniRef50_A1QYK2 tRNA (Guanosine-2'-O-)-methyltransferase n=7 Tax=Borrelia
           RepID=A1QYK2_BORT9
          Length = 232

 Score =  100 bits (249), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 52/169 (30%), Positives = 88/169 (52%), Gaps = 1/169 (0%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA 64
           R  RI E+L+ R   LT+ +E + +P N SA +RT + +G+  +H +   +         
Sbjct: 34  RRERIDEVLSNRTNYLTLVLEDIFQPQNASATMRTIEILGLSNIHIIETNNTYTLNPGVV 93

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTG 124
            G++ W+ +  ++ +  A  +LKG G +I+AT L + A+   +        I  G E TG
Sbjct: 94  LGASKWIDIIKYQCVESAFDNLKGNGYKIVATSLDNEAIFLDDFPIDDKMAIFFGTELTG 153

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYE-AQRQRQNAGMYL 172
           ++   L  AD  + IPM G  QS N+SVA +++ Y    R R+++  YL
Sbjct: 154 LSNTVLENADLHLKIPMYGFTQSYNLSVAVSIVFYSLISRLRKSSIKYL 202


>UniRef50_Q9LXE4 rRNA methylase-like protein n=11 Tax=Magnoliophyta
           RepID=Q9LXE4_ARATH
          Length = 350

 Score =  100 bits (248), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 63/187 (33%), Positives = 100/187 (53%), Gaps = 8/187 (4%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMAS-- 62
           R+ R+ E    R   + + +E +    N+SA  R+ADA+G+  VH V   S  R   +  
Sbjct: 143 RFRRVVE---NRSYSVCLVVEGLSDFGNISAAFRSADALGIQSVHVVSCDSSKRYNGNRH 199

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
            + G+  W+ ++   T  +    LK +G +I  THL  + V   ++D++ PT I++G E 
Sbjct: 200 VSMGAEKWLDIEFWDTPKECFKVLKSRGYRIATTHLGMDTVSIYDMDWSCPTAIVVGNEG 259

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAE 182
            GI+ EAL L+D    IPM GMV S NVSVA+ ++++ A   R      L  +  L EAE
Sbjct: 260 RGISDEALELSDLRCSIPMNGMVDSFNVSVAAGILMHHAVSDRTTR---LGSHGDLSEAE 316

Query: 183 QQRLLFE 189
           ++ L+ E
Sbjct: 317 KEILMAE 323


>UniRef50_B0MYM4 Putative uncharacterized protein n=1 Tax=Alistipes putredinis DSM
           17216 RepID=B0MYM4_9BACT
          Length = 228

 Score = 99.8 bits (247), Expect = 7e-20,   Method: Compositional matrix adjust.
 Identities = 50/149 (33%), Positives = 86/149 (57%), Gaps = 3/149 (2%)

Query: 13  LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQ 72
           L  R   +T+  E  +   N SA++R  +A GV ++H +    +     +   G++ W+ 
Sbjct: 35  LDSRTRYMTILTENTYHAQNASALVRHCEAFGVQDIHTIETRCKFNPNVNIVRGTDKWID 94

Query: 73  VKTHRTIGDAVAHLKGQGMQILAT--HLSDNAVDFREIDYTRPTCILMGQEKTGITQEAL 130
           +  HRT  +A+A LKG+G +I+AT  H  D   +  ++  + P  ++ G E  GI+ E +
Sbjct: 95  LHRHRTTAEAIADLKGRGYRIVATTPHREDKTPETFDVAAS-PFVLVFGTEHAGISDEIV 153

Query: 131 ALADQDIIIPMIGMVQSLNVSVASALILY 159
           A AD+ + IPM GMV+SLNVS ++A+++Y
Sbjct: 154 AAADEFLRIPMCGMVESLNVSASAAILIY 182


>UniRef50_Q14PR4 Putative trna/rrna methyltransferase protein n=1 Tax=Spiroplasma
           citri RepID=Q14PR4_SPICI
          Length = 244

 Score = 99.4 bits (246), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 59/158 (37%), Positives = 90/158 (56%), Gaps = 7/158 (4%)

Query: 13  LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM----RTMASAAAGSN 68
           L  + P L V ++Q+  PHN  AI+RT D   V  V  +    R      T+A  +AG+ 
Sbjct: 90  LQNKHPFLLV-LDQISDPHNFGAILRTCDLFNVDGV--IILDKRQVDINATVAKTSAGAF 146

Query: 69  SWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQE 128
           ++V V     + +A+ +LK QG  I AT L+  A +  E+ Y  P C+++G E TGI+ +
Sbjct: 147 NYVPVCRVNNLTNAIEYLKKQGFWIYATSLNTKAQNVSELKYDIPICLIVGNEGTGISAK 206

Query: 129 ALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            L  AD +I IP  G + SLNVSVASA+++Y+ +  +Q
Sbjct: 207 LLKHADFNIYIPTAGHLDSLNVSVASAILIYQIKMLQQ 244


>UniRef50_Q112U6 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Oscillatoriales
           RepID=Q112U6_TRIEI
          Length = 234

 Score = 98.6 bits (244), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 50/164 (30%), Positives = 85/164 (51%), Gaps = 5/164 (3%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           + P R  +I  +L +R  D+TV +E +++PHN SA++R+ D+ GV +VH V   +     
Sbjct: 17  ITPARREKILSVLQQRTRDITVILEDIYQPHNASAVLRSCDSFGVQDVHIVENKNIFTIT 76

Query: 61  ASAAAGSNSWVQVKTH-----RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
            S   GS+ W+ +  +         + +  LK +G  I AT      +   E+       
Sbjct: 77  QSVTIGSDRWLTLYRYNEQSINNTEECLKRLKNEGYVIAATTPYKEHITIEELSVNTKVA 136

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILY 159
           ++ G E  G+++ A   AD  + IPM+G  +S N+SV++AL LY
Sbjct: 137 LMFGSEINGLSEYAKNNADVSVKIPMVGFSESFNISVSAALCLY 180


>UniRef50_C6WZC0 tRNA (Guanosine18-2'-O-)-methyltransferase n=1
           Tax=Flavobacteriaceae bacterium 3519-10
           RepID=C6WZC0_FLAB3
          Length = 255

 Score = 95.1 bits (235), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 48/156 (30%), Positives = 82/156 (52%), Gaps = 2/156 (1%)

Query: 24  MEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGDAV 83
           ME + +  N +AI+R+ +A G H++ A+   +          G+ +WV+V+      +++
Sbjct: 72  MEDIFQFRNAAAIVRSVEACGFHKIVAMESENEFNPNLRVTKGAETWVEVEKMPHNLESL 131

Query: 84  AHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIG 143
             +K +G +ILA     NA    +     P  ++ G EK G+T+E L  AD+ + IPM G
Sbjct: 132 TEIKNRGYKILAVSPEKNATMLPDYQLKEPVALVFGTEKEGVTEEILDFADETVAIPMYG 191

Query: 144 MVQSLNVSVASALILYEAQRQ--RQNAGMYLRENSM 177
             +S NVSVA+A+  YE +++  R N    L E  +
Sbjct: 192 FTRSFNVSVAAAICFYELKQKLIRSNIDYKLSEEKL 227


>UniRef50_A5IXH9 tRNA/rRNA methyltransferase n=1 Tax=Mycoplasma agalactiae PG2
           RepID=A5IXH9_MYCAP
          Length = 233

 Score = 94.0 bits (232), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 49/154 (31%), Positives = 84/154 (54%), Gaps = 6/154 (3%)

Query: 11  EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA--AGSN 68
           +++ +  P   + ++ +H PHN  AIIRTA+A G+   H + P  R   + S      S 
Sbjct: 76  DVIKKDNPKTVLILDHIHDPHNFGAIIRTANAAGIK--HIIIPKDRSTDVTSTVLKVSSG 133

Query: 69  SWVQVKTHR--TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
            +V VK  +   I  ++  LK  G  I ++ L +NAV + ++ Y     +++G E+ GI+
Sbjct: 134 GFVGVKIIKVSNIASSIEKLKKWGFWIYSSLLDENAVPYNKVQYAGNCALVVGNEEKGIS 193

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYE 160
           +  +   D  + IP  G VQS+NVSVA+ ++L+E
Sbjct: 194 KPVVNATDVKVYIPQFGTVQSMNVSVATGILLFE 227


>UniRef50_A6G083 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Plesiocystis pacifica
           SIR-1 RepID=A6G083_9DELT
          Length = 240

 Score = 93.6 bits (231), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 55/174 (31%), Positives = 84/174 (48%), Gaps = 10/174 (5%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA 64
           R  RI  +L  R   + V +E  + PHN +A++R+ +A+G   VH +    R+       
Sbjct: 30  RRERIESVLDARLASVQVAIENPYDPHNAAAVVRSTEALGGWTVHVIAAHERILRAKGTT 89

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQ----------ILATHLSDNAVDFREIDYTRPT 114
            G++ W++ + HRT+ D  AHL                ILA    D      E+   RP 
Sbjct: 90  TGTHHWLETRNHRTLADFEAHLGPARAAGGAGGPGEGMILAGACVDATHMLEELPVDRPL 149

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           C+L G E  G++ EA A  D    IP+ G  +S N+SV++AL LY    +R+ A
Sbjct: 150 CLLFGNEHAGLSPEAKASCDLRFRIPIHGFAESYNLSVSAALTLYSVTTRRRAA 203


>UniRef50_A3HSD9 SpoU protein (SpoU) n=1 Tax=Algoriphagus sp. PR1 RepID=A3HSD9_9SPHI
          Length = 234

 Score = 93.6 bits (231), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 53/183 (28%), Positives = 88/183 (48%), Gaps = 10/183 (5%)

Query: 11  EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSW 70
           ++LA+R    TV +E ++KPHN SA++RT D  G+ +VH +      +       G++ W
Sbjct: 31  KVLAQRTRHFTVVLENIYKPHNASAVLRTCDCFGIQDVHIIEKTREYKVNPFVTRGASQW 90

Query: 71  VQVKTH-------RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           + +  +         + +  + LK  G +I  T         +++D      ++ G E  
Sbjct: 91  LTLHKYFQPEEPENAVINCFSSLKSNGFKIYGTSPDPQTRPIQDLDPNEKIALVFGNEHE 150

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAEQ 183
           GI+ E    AD  + IPM G  +S N+SVA++L L   Q   Q A  Y+  +  L E E+
Sbjct: 151 GISNEVKNAADGLVHIPMRGFTESFNISVAASLFL---QNLVQKASDYVIPDYNLTEVEK 207

Query: 184 QRL 186
           Q L
Sbjct: 208 QEL 210


>UniRef50_Q2S465 RRNA methylase n=1 Tax=Salinibacter ruber DSM 13855
           RepID=Q2S465_SALRD
          Length = 247

 Score = 93.6 bits (231), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 54/166 (32%), Positives = 88/166 (53%), Gaps = 1/166 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAV-WPGSRMRT 59
           M   R  RI  ++A R   +   +E +    NVSA++R+A+A+G  ++H V     R + 
Sbjct: 38  MRERRLDRIQTVVANRTRSVVPVVEGLVNTGNVSAVMRSAEALGHQDMHVVSGEHDRYKH 97

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
               A G+  W+ V           HL+  G +++A HL  + V  R++D+T+PT ++ G
Sbjct: 98  SQRTAQGAQHWLDVWHWDAPTACATHLQDAGYRVVAMHLHADTVPIRDLDFTQPTALVFG 157

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            E  G+T   L  +D    +P+ G  +S NVSVA+A+ LY AQ+ R
Sbjct: 158 NEDAGVTDTMLEASDAACEVPLPGFTESFNVSVAAAVALYHAQQDR 203


>UniRef50_B5GW91 tRNA/rRNA methyltransferase n=1 Tax=Streptomyces clavuligerus ATCC
           27064 RepID=B5GW91_STRCL
          Length = 182

 Score = 93.2 bits (230), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 50/148 (33%), Positives = 83/148 (56%), Gaps = 2/148 (1%)

Query: 19  DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMAS--AAAGSNSWVQVKTH 76
           ++ + +E V  P NV +I+RTA A+GV  ++     +  R   +     G++ ++ V+T 
Sbjct: 26  EVALLLENVQSPFNVGSIVRTAAALGVGRLYLAGNTASPRNAKAQKICMGTDRYLDVQTF 85

Query: 77  RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQD 136
            T+ +AV  ++  G +++   L+D AV   E D +  TCI +G E  GI+ +AL + D  
Sbjct: 86  ETLPEAVERVRADGYRLVGLELADEAVPLHEADLSGATCIAVGNEDHGISPQALGMCDAV 145

Query: 137 IIIPMIGMVQSLNVSVASALILYEAQRQ 164
             IP +G V SLNV+ A A+  YE +RQ
Sbjct: 146 AFIPQLGRVGSLNVATALAVACYEVRRQ 173


>UniRef50_B3PM16 SpoU class tRNA/rRNA methyltransferase n=1 Tax=Mycoplasma
           arthritidis 158L3-1 RepID=B3PM16_MYCA5
          Length = 229

 Score = 92.0 bits (227), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 44/157 (28%), Positives = 88/157 (56%), Gaps = 6/157 (3%)

Query: 13  LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAAGSN 68
           + + +P+L + ++ +  PHN  AIIR A+  G+   H + P +R      T+   ++G+ 
Sbjct: 75  IFKDKPNLVLMLDHIQDPHNFGAIIRNANGFGIK--HIIIPKNRACEVTPTVLKISSGAF 132

Query: 69  SWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQE 128
           + +++    ++ D +  L+  G  I ++ L D A    +  +  PTC+++G E++G++  
Sbjct: 133 TEIKIIRVGSLFDTLKELQKNGFWIYSSTLDDKATKLHKTKFATPTCLIVGNEESGVSHT 192

Query: 129 ALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            +  +D  + I   G VQSLNV+ A+A++LYEA ++ 
Sbjct: 193 LIKHSDALVYIEQKGTVQSLNVASATAVLLYEATKEN 229


>UniRef50_Q09CR8 RRNA methylase n=2 Tax=Cystobacterineae RepID=Q09CR8_STIAU
          Length = 226

 Score = 91.7 bits (226), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 52/202 (25%), Positives = 99/202 (49%), Gaps = 12/202 (5%)

Query: 4   TRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW-PGSRMRTMAS 62
            R  +I  ++ +R    TV ++++    N++A++RT +A+GV EVH V  P +     + 
Sbjct: 25  VRKEKIDRVVEQRTRTFTVVLDRLEDSFNMAAVLRTCEAMGVQEVHVVINPEAPFLPNSR 84

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
            A G + W+ VK ++T  +   HL+ +G  + A+ + + A     + +     I+ G E+
Sbjct: 85  VAQGCDKWLDVKLYKTFAECREHLQERGFALYASAIREGATSLYSMRFDSKVAIVFGNER 144

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR-----------QNAGMY 171
            G++++ LA  D    IPM G  QS+N+S A++  +      R           +     
Sbjct: 145 FGVSEDVLAGVDGTFWIPMRGFSQSINISAAASACVSRVMAWREEHLGKVGDLTEEEAQA 204

Query: 172 LRENSMLPEAEQQRLLFEGGYP 193
           LRE   +   +Q++ +F+G  P
Sbjct: 205 LRERFYVLALKQRKRIFKGKQP 226


>UniRef50_C0YTB0 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Chryseobacterium gleum
           ATCC 35910 RepID=C0YTB0_9FLAO
          Length = 226

 Score = 91.3 bits (225), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 49/171 (28%), Positives = 91/171 (53%), Gaps = 3/171 (1%)

Query: 11  EMLARRQPDLTV-CMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNS 69
           E  ++   D  +  +E V++  N +AI+R+ +A G H+V A+              G+++
Sbjct: 26  EHFSKESSDFVLPVVEDVYQFRNAAAIVRSVEACGFHKVVALQEEYSFEPNLRVTKGADT 85

Query: 70  WVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEA 129
           WV+V+      ++  ++K +  +I+A  L  NA    E + T P  ++ G E  G++QE 
Sbjct: 86  WVEVEKLPRNMESFQNIKDRRYKIVAVSLEKNAKMLPEYEVTEPIALVFGTEMEGVSQEI 145

Query: 130 LALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ--RQNAGMYLRENSML 178
           L  AD+ + IPM G  +S NVSVA+++ +YE +++  + +    L E  +L
Sbjct: 146 LDFADETLAIPMYGFTRSFNVSVAASICMYELKQKLIKSDIDYKLNEEKLL 196


>UniRef50_A9GR15 tRNA (Guanosine-2'-O-)-methyltransferase n=1 Tax=Sorangium
           cellulosum 'So ce 56' RepID=A9GR15_SORC5
          Length = 508

 Score = 91.3 bits (225), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 52/161 (32%), Positives = 89/161 (55%), Gaps = 1/161 (0%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA 64
           R AR+  ++A R   +TV M+  H PHN +A++R+ DA G+  +H +    +     + +
Sbjct: 42  RRARLRGVIAARLDAVTVAMDAPHDPHNGAAVLRSCDAFGLQRLHIIERAEQFLVSNTVS 101

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTG 124
            GS  WV V+TH +   AVA L+  G +++ATH  +  +  R++       +++G E+ G
Sbjct: 102 RGSERWVDVRTHASTEAAVAELRASGHELVATH-PEGELTPRDLSSIPRLALVLGNERDG 160

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           I  +  A   + + +PM G  +SLNVSV +A++L  A   R
Sbjct: 161 IRPDLAAACARAVRVPMRGFAESLNVSVTAAILLEHATNGR 201


>UniRef50_C7NJ34 rRNA methylase n=2 Tax=Micrococcineae RepID=C7NJ34_KYTSD
          Length = 271

 Score = 91.3 bits (225), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 61/165 (36%), Positives = 88/165 (53%), Gaps = 4/165 (2%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTM 60
           PT    + ++     P L V  E + KP N+ AI+RTADA GV  V A  P +      +
Sbjct: 107 PTPGVALADLPQPDGPGLYVVAEHLEKPGNLGAILRTADAAGVDAVIAADPVTDWGNPNV 166

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              + G+   V V T  T  + +  L G+GM ++AT      V   ++D T P  I +G 
Sbjct: 167 VRGSKGTVFSVPVATAPTP-EVLDFLAGRGMTLVATT-PHTEVLHTQVDLTGPVAIAVGA 224

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           EKTG+T  AL  A   + IPM+G   SLNV+ ++A+++YEA RQR
Sbjct: 225 EKTGLTASALEGATHRVRIPMVGRANSLNVATSAAIVVYEAVRQR 269


>UniRef50_A1HPG2 TRNA/rRNA methyltransferase (SpoU) n=1 Tax=Thermosinus
           carboxydivorans Nor1 RepID=A1HPG2_9FIRM
          Length = 270

 Score = 90.5 bits (223), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 57/156 (36%), Positives = 89/156 (57%), Gaps = 11/156 (7%)

Query: 19  DLTVCMEQVHKPHNVSAIIRTADAVGVHEV------HAVWPGSRMRTMASAAAGSNSWVQ 72
           +L V ++ V  P NV  ++RTADA G   V        ++ G  +R    A  GS   + 
Sbjct: 118 ELIVVLDNVQDPGNVGTVVRTADAAGCCGVILTKGCADLFSGKTVR----ATMGSLFHLP 173

Query: 73  VKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALAL 132
           V T     +  A L+ QG+++LAT L D++  + ++D   P  I+ G E  G+++  L  
Sbjct: 174 VITGVAEQEVAAFLERQGIRLLATAL-DSSSLYHDVDLRSPVAIVFGNEGAGVSKVILEK 232

Query: 133 ADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           AD+ + IP+ G  +SLNV+VA+A+ILYEA+RQR+ A
Sbjct: 233 ADERLYIPLYGRAESLNVAVAAAVILYEARRQRRVA 268


>UniRef50_B3QM30 RNA methyltransferase, TrmH family, group 3 n=12 Tax=Chlorobiaceae
           RepID=B3QM30_CHLP8
          Length = 257

 Score = 90.1 bits (222), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 61/159 (38%), Positives = 92/159 (57%), Gaps = 5/159 (3%)

Query: 11  EMLA--RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAV-WPGSRMR-TMASAAAG 66
           E+LA  R    L V ++ +  PHNV AIIRTA+AV    V  +   G+ +  T+  A+AG
Sbjct: 98  EVLAAPRNSSPLLVILQGLEDPHNVGAIIRTAEAVAADSVIMIEGKGAPISATVHKASAG 157

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           + S ++V   +++   +  L  +G  I+A  +     +  +ID+ RPT ++MG E  G+ 
Sbjct: 158 ALSHMRVCKVKSLVKTLDLLHERGFSIVAADMEAEH-NHTDIDWKRPTVLVMGAEGKGLG 216

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            E     DQ + IPM G V+SLNVSVA+ ++LYEA RQR
Sbjct: 217 SETRKRCDQIVRIPMAGCVESLNVSVAAGVMLYEAMRQR 255


>UniRef50_C2FZ75 Possible tRNA/rRNA methyltransferase n=2 Tax=Sphingobacterium
           spiritivorum RepID=C2FZ75_9SPHI
          Length = 259

 Score = 89.4 bits (220), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 56/173 (32%), Positives = 93/173 (53%), Gaps = 9/173 (5%)

Query: 1   MNPTRYARI----CEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++P  Y +I     E+  + +  L + ++ V    N+ AI RTA+  GVH +     GS 
Sbjct: 86  ISPITYQKIEDLIPEIYEKGETPLILMLDGVTDVRNLGAIARTAECSGVHAIIVPKKGSA 145

Query: 57  MRT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQ-ILATHLSDNAVDFREIDYTRP 113
                    +AG+   + V  H  +G     L   G+Q +++T  ++ ++    +DYT P
Sbjct: 146 EINPDAIKTSAGALYKIPVCRHDNLGKVGKFLIDSGIQLVVSTEKTEESI--YSVDYTAP 203

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           TCI+MG E  G++ + + ++D    IPM G + SLNVSV++ ++LYEA RQRQ
Sbjct: 204 TCIIMGAEDVGVSDDLIRISDHLAKIPMFGEIGSLNVSVSAGVVLYEAIRQRQ 256


>UniRef50_B0TC37 RNA methyltransferase, trmh family n=1 Tax=Heliobacterium
           modesticaldum Ice1 RepID=B0TC37_HELMI
          Length = 256

 Score = 88.6 bits (218), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 56/174 (32%), Positives = 89/174 (51%), Gaps = 11/174 (6%)

Query: 3   PTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP----G 54
           P  Y  + E+L    A+ +P   + ++ +  PHN+ A++RTA+  G H V  + P    G
Sbjct: 81  PVAYVEVEEILEKAKAKGEPPFVLLLDGLEDPHNIGALLRTAEGAGAHGV--IIPKRRGG 138

Query: 55  SRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
           +   T+A A+AG+  +V +     +   V  LK  G+ I+ + +      FR+ D+  P 
Sbjct: 139 AITSTVAKASAGAVEYVPIARVTNLVQTVGQLKKAGLWIIGSAMDAPRPYFRQ-DFRGPV 197

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
            +++G E  GI+       D  + IPM G V SLN SVA AL++YE  RQ Q  
Sbjct: 198 GLIVGSEGKGISPLLREHCDHLVSIPMGGKVDSLNASVAGALLMYERVRQLQEG 251


>UniRef50_C1E8J5 Predicted protein (Fragment) n=3 Tax=Mamiellales RepID=C1E8J5_9CHLO
          Length = 234

 Score = 88.6 bits (218), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 54/187 (28%), Positives = 100/187 (53%), Gaps = 5/187 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW-PGSRMRT 59
           ++  R AR+  ++ +R  DL   +E V+   NV A+ R+ +A+G+  +  +   G   + 
Sbjct: 28  VSEERIARLDAVVQQRSFDLMPILEGVYDIGNVLAVCRSTEALGIGSLGVISDAGLAFKQ 87

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
               + G+  W  ++  R+  +A+  +K +G ++L T + +        D+T PT +++G
Sbjct: 88  SGRTSGGAVKWTNLEQWRSTEEAIREVKARGYRVLTT-VFEGGHPLEHYDWTVPTAVILG 146

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E+ G++ EA  LAD  + I M G  +SLNVSVAS++I++ A + R      L  +  L 
Sbjct: 147 NERDGVSDEAKRLADGGVYISMNGFTESLNVSVASSMIMHHAVQDRTRR---LGSHGNLS 203

Query: 180 EAEQQRL 186
           E E++ L
Sbjct: 204 EREKETL 210


>UniRef50_Q6FF50 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=19
           Tax=Moraxellaceae RepID=RLMB_ACIAD
          Length = 248

 Score = 88.2 bits (217), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 55/160 (34%), Positives = 86/160 (53%), Gaps = 7/160 (4%)

Query: 11  EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA----SAAAG 66
           ++L      L + ++QV  PHN+ A IRTA A+G+  V  + P  R  ++       AAG
Sbjct: 89  QLLQNNDQALLLALDQVTDPHNLGACIRTAAAMGIAAV--IVPRDRSASLTPTARKVAAG 146

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGM-QILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
               V+      +   +AH+K     +++ T L + A+  ++ D++    I+MG E TG+
Sbjct: 147 GAEKVKFIQVTNLARTLAHIKAHFFVKVVGTMLDEKALPIQKYDFSGNVAIVMGAEDTGL 206

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
                +  DQ + IPM G +QSLNVSVA+ + LYEA RQR
Sbjct: 207 RPITQSQCDQTVYIPMSGNLQSLNVSVAAGMALYEACRQR 246


>UniRef50_B5YID5 RNA methyltransferase, TrmH family, group 3 n=1
           Tax=Thermodesulfovibrio yellowstonii DSM 11347
           RepID=B5YID5_THEYD
          Length = 248

 Score = 87.8 bits (216), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 56/158 (35%), Positives = 83/158 (52%), Gaps = 7/158 (4%)

Query: 13  LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAAGSN 68
             + +P   + ++ V  P N  +I R ADA GVH +  ++   R    + ++  A+AG+ 
Sbjct: 92  FKKNEPAFFLILDLVEDPQNFGSICRIADAAGVHAI--IYQKKRSVGIVPSVWKASAGAV 149

Query: 69  SWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQE 128
             V +     I  A+  LK   + I         V F E D+T+P  +++G E  GI Q 
Sbjct: 150 WHVNLVEINNIKYAIKTLKEHNITIYGAEAQAKDV-FWESDFTQPLGLIVGSEGKGIRQT 208

Query: 129 ALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            +AL D+ I IPM G + SLNVSVASALI +E  RQR+
Sbjct: 209 VIALCDKVIKIPMRGTINSLNVSVASALITFEVLRQRK 246


>UniRef50_C3RMB5 23S rRNA methyltransferase n=5 Tax=Bacteria RepID=C3RMB5_9MOLU
          Length = 244

 Score = 87.8 bits (216), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 55/170 (32%), Positives = 92/170 (54%), Gaps = 12/170 (7%)

Query: 5   RYARICEMLAR----RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--- 57
           RY  I E++      +QP L + ++ +  PHN+ AI+RT DA+GV  V  +   +R    
Sbjct: 77  RYYSIDEIINTIPDGKQP-LLLMLDGLEDPHNLGAILRTCDAIGVDGV--IIGKNRSVGL 133

Query: 58  -RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
             T+A  + G+   V+V     +   +  LK +   ++   L D + D+R++DY  P  I
Sbjct: 134 NGTVAKVSTGAIDHVKVAQVTNLTRTLEDLKKRSFWVVGCDL-DKSQDYRQVDYNMPLVI 192

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           ++G E  GI++      D ++++PM+G V SLN SVA+A+ILY+    R 
Sbjct: 193 VIGSEGFGISRLVKKSCDINVVLPMVGHVNSLNASVATAVILYQVYNSRN 242


>UniRef50_A6DFW8 SpoU protein n=1 Tax=Lentisphaera araneosa HTCC2155
           RepID=A6DFW8_9BACT
          Length = 233

 Score = 87.4 bits (215), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 53/181 (29%), Positives = 92/181 (50%), Gaps = 8/181 (4%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA 64
           R   I ++ + R   + + +E +++ HN SAI+R ADA G+  ++ +   +        +
Sbjct: 28  RIELIDKVCSERTEHICLVLENLYQEHNASAILRNADAFGIQNINVIENDNDFAANKEVS 87

Query: 65  AGSNSWVQVK--THRTIGDAV---AHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
             ++ W+ +K      I + V   + LK QG +I AT L   ++   E+    P  +  G
Sbjct: 88  MSAHKWLDIKAWNESKIDNTVKCLSALKKQGYKICATSLRPESITLDELPVDEPIALCFG 147

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E TG+++ A  +AD    IPM G +QS NVSVASAL L   + + +   +   E+++ P
Sbjct: 148 TELTGLSEVAHEMADYMTYIPMNGFIQSFNVSVASALSLSHLRNKMKRKNI---EHALSP 204

Query: 180 E 180
           E
Sbjct: 205 E 205


>UniRef50_A4S6N6 Predicted protein (Fragment) n=1 Tax=Ostreococcus lucimarinus
           CCE9901 RepID=A4S6N6_OSTLU
          Length = 216

 Score = 87.0 bits (214), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 53/164 (32%), Positives = 82/164 (50%), Gaps = 2/164 (1%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP-GSRMRTMASA 63
           R  R+  +L  R   L   +E V+   N+ A+ RT +A+G+     V   G   +     
Sbjct: 31  RRMRLENVLEHRSFSLLPILEGVYDVGNILAVCRTTEALGIGCASIVSSKGLSFKASGRT 90

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           + G+  W  V+   T   A+   K +G ++L T   D A      D+T PT ++ G E+ 
Sbjct: 91  SGGALKWQHVEQFETSERALRVAKAKGYRVLTTEF-DGAQPLSHYDWTVPTAVVFGNERE 149

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           G++ EA AL D  + IPM G  +SLN+SVA+AL++  A   R N
Sbjct: 150 GVSDEARALRDGAVYIPMFGFTESLNISVAAALVMSHAVTDRIN 193


>UniRef50_C6X1H8 rRNA methylase n=4 Tax=Bacteroidetes RepID=C6X1H8_FLAB3
          Length = 265

 Score = 86.7 bits (213), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 51/138 (36%), Positives = 80/138 (57%), Gaps = 7/138 (5%)

Query: 32  NVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA----AGSNSWVQVKTHRTIGDAVAHLK 87
           N  AI RTA+ VGVH +  + P      + S A    AG+   +++   + +  AV  L+
Sbjct: 126 NFGAICRTAECVGVHAI--ILPEKGAAPINSDAIKTSAGAIYNLRICKEKNLAHAVDFLQ 183

Query: 88  GQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQS 147
             G+Q+ +       + + ++D+T+P  I+MG E+TGI++E L  +D+ I +P+ G  QS
Sbjct: 184 QSGLQVFSASEKAQKLIY-DVDFTQPCAIVMGNEETGISKEVLHHSDEKIKLPIEGKTQS 242

Query: 148 LNVSVASALILYEAQRQR 165
           LNVSVA   ILYEA RQ+
Sbjct: 243 LNVSVACGAILYEAVRQK 260


>UniRef50_A6LPP3 RNA methyltransferase, TrmH family, group 3 n=35 Tax=Firmicutes
           RepID=A6LPP3_CLOB8
          Length = 300

 Score = 86.7 bits (213), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 46/173 (26%), Positives = 92/173 (53%), Gaps = 11/173 (6%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P +Y+ + ++L     R +    V +++V  PHN+ +I+RTA+  GVH +  + P  R
Sbjct: 129 VTPYKYSEVSDILDLAEKRGEAPFIVILDEVEDPHNLGSIVRTAELFGVHGI--ILPKRR 186

Query: 57  MRTMAS----AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR 112
             ++++    ++ G+   V++     +   +  LK +G+ I    +      + ++D+  
Sbjct: 187 SASVSTTVYKSSVGAIEHVKIAKVTNLNSTIEELKEKGIWIYGADIRAEEYSY-QVDFGG 245

Query: 113 PTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           P  +++G E  GI++  +   D+ I IPM+G + SLN SVA  +I+YE  + R
Sbjct: 246 PCAVIIGNEGRGISKLTVEKCDKLIKIPMVGKINSLNASVAGGIIMYEVLKGR 298


>UniRef50_Q5HIE3 Putative trmH family tRNA/rRNA methyltransferase n=86
           Tax=Firmicutes RepID=TRMHL_STAAC
          Length = 248

 Score = 86.3 bits (212), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 58/175 (33%), Positives = 93/175 (53%), Gaps = 11/175 (6%)

Query: 3   PTRYARICEMLARRQPD---LTV-CMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR-- 56
           P  YA   + L +++     LTV  ++ +  PHN+ +I+RTADA GV  V  + P  R  
Sbjct: 75  PYEYADFDQFLKQQKEKEGLLTVLILDGLEDPHNLGSILRTADATGVDGV--IIPKRRSV 132

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
              +T+A A+ G+   V V     +   +  LK  G  +  T  ++NA D+R ++     
Sbjct: 133 TLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTE-ANNATDYRNLEADMSL 191

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
            I++G E  G+++      D  I IPM+G V SLN SVA++L++YE  R+R + G
Sbjct: 192 AIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFRKRHDVG 246


>UniRef50_C8P2I4 23S rRNA (Guanosine-2'-O-)-methyltransferase RlmB n=1
           Tax=Erysipelothrix rhusiopathiae ATCC 19414
           RepID=C8P2I4_ERYRH
          Length = 236

 Score = 86.3 bits (212), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 55/166 (33%), Positives = 90/166 (54%), Gaps = 6/166 (3%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTM 60
           +Y  + E++   + +L V  +Q+  PHN+ AI+RT DA GV  V  V    R      T+
Sbjct: 73  KYHSLQEIIKGAKNNLIVLCDQLEDPHNLGAILRTCDACGVDGV--VVGKHRSVGLTSTV 130

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
           A  + G+ + V+V     +  A+A LK  G  ++A   + +AVD+ E +   P  +++G 
Sbjct: 131 AKVSTGAINTVKVAEATNMVKAIAELKEAGYWVVAAENAVDAVDYTEFNVDMPLVLVVGS 190

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           E  GI++      D    IPM G V SLNVSVA+ ++L++  R+R+
Sbjct: 191 EGKGISRLVKKECDILTTIPMQGSVNSLNVSVATGVLLFDIVRRRK 236


>UniRef50_C9RPE6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Fibrobacter succinogenes
           subsp. succinogenes S85 RepID=C9RPE6_FIBSS
          Length = 218

 Score = 86.3 bits (212), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 52/187 (27%), Positives = 95/187 (50%), Gaps = 8/187 (4%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA 64
           R   +  ++ RR     + +E +  PHN+SA+IRTA+  G+ +VH +   +      S  
Sbjct: 18  RRELLTSVVNRRTRHFCMVLEDLFDPHNISAVIRTAEVFGLQDVHIIEEDNAYSVNKSIL 77

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQI--LATHLSDNAVDFREIDYTRPTCILMGQEK 122
            GS  W+ +  ++     +  L+ +G +I   +T+ +++ +D   +D ++P    +G E 
Sbjct: 78  KGSYKWMSLYLYKKRMLCMEKLREKGYKIAVASTNTTNSVLD---LDLSQPMAFYLGSEF 134

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAE 182
            G   + LA AD +  +P  G+ +S+NVSVA  +++       Q  G   RE   LP+AE
Sbjct: 135 HGNHPDTLAHADYEFKLPQYGITESMNVSVAGGVLMTYLDVFMQKQG---REKFALPQAE 191

Query: 183 QQRLLFE 189
           +  LL +
Sbjct: 192 RDALLLD 198


>UniRef50_Q5HRM1 Putative trmH family tRNA/rRNA methyltransferase n=7
           Tax=Staphylococcaceae RepID=TRMHL_STAEQ
          Length = 249

 Score = 85.9 bits (211), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 56/171 (32%), Positives = 89/171 (52%), Gaps = 11/171 (6%)

Query: 3   PTRYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR-- 56
           P  YA   E L +++        + ++ +  PHN+ +I+RTADA GV  V  + P  R  
Sbjct: 75  PYEYANFDEFLQKQKKKARYSTVIILDGLEDPHNLGSILRTADASGVDAV--IIPKRRSV 132

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
              +T+A A+ G+   V V     +   +  LK  G  I  T  ++NA D+R++      
Sbjct: 133 ALTQTVAKASTGAIQHVPVIRVTNLSKTIDELKDNGFWIAGTE-ANNATDYRDLQADMSL 191

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            I++G E  G+++      D  I IPM+G V SLN SVA++L++YE  R+R
Sbjct: 192 GIVIGSEGQGMSRLVSDKCDFHIKIPMVGHVNSLNASVAASLMMYEVYRKR 242


>UniRef50_B3ETE6 Putative uncharacterized protein n=1 Tax=Candidatus Amoebophilus
           asiaticus 5a2 RepID=B3ETE6_AMOA5
          Length = 246

 Score = 85.9 bits (211), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 53/152 (34%), Positives = 82/152 (53%), Gaps = 7/152 (4%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA----AGSNSWVQVKT 75
           L + ++ V    N+ AI+RTA  VG H +  V P     ++ S A    AG+ + + +  
Sbjct: 97  LIIILDGVTDVGNLGAIVRTAVCVGAHAL--VLPKQGSASLGSGAMKTSAGALAHLPICR 154

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
              +  ++ +L+  G+Q++A H         ++  T PT IL+G E  GI  + L   D 
Sbjct: 155 EANLQASINYLQNSGLQVIACH-EKTQTSIYQVKLTVPTAILLGSEDKGIQPQLLNKVDV 213

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
              IPM+G + SLNVSVA+A+ILYE+ RQR N
Sbjct: 214 QASIPMVGPISSLNVSVAAAIILYESFRQRNN 245


>UniRef50_Q4A787 TRNA/rRNA methyltransferase n=4 Tax=Mycoplasma RepID=Q4A787_MYCH7
          Length = 233

 Score = 85.9 bits (211), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 46/153 (30%), Positives = 79/153 (51%), Gaps = 6/153 (3%)

Query: 11  EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM----RTMASAAAG 66
           + L + +P + + ++ +   +N+  IIRTA+  G+   H + P  R      T    ++G
Sbjct: 72  DTLVKDKPKIILILDHIQDQNNLGNIIRTANCFGIK--HIILPKKRAAKLNETTMKVSSG 129

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
               ++     +I  A+  LK     I AT L + +   +EI +  P  I++G E TGI 
Sbjct: 130 GFVGLKFILVNSIVSAINKLKEMDFWIYATDLKEKSRKIQEIQFNYPCAIILGNEATGIK 189

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILY 159
           + +L  +DQ   IP+ G V SLNV+VA+ +IL+
Sbjct: 190 KSSLNASDQTFFIPLEGTVNSLNVTVATGIILF 222


>UniRef50_C9KPX8 RNA methyltransferase, TrmH family n=1 Tax=Mitsuokella multacida
           DSM 20544 RepID=C9KPX8_9FIRM
          Length = 271

 Score = 85.9 bits (211), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 60/161 (37%), Positives = 85/161 (52%), Gaps = 12/161 (7%)

Query: 14  ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHA------VWPGSRMRTMASAAAGS 67
           A R+P L V ++ V  P N   IIRTADAVG   V        V+    +R    A  GS
Sbjct: 117 AARKP-LLVVLDGVQDPGNAGTIIRTADAVGADGVILTKGSVDVFSDKTVR----ATMGS 171

Query: 68  NSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQ 127
              + V T  +  +     +  G Q+LAT L + A     +D+ + + I  G E  G+++
Sbjct: 172 LFHLPVVTDVSAEEVATFAQAAGCQLLATALDEQAKPHFAVDFGKGSLIAFGNEGGGVSE 231

Query: 128 EALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           E LA A++ + IPM G  +SLNV V+SA++LYEA RQR  A
Sbjct: 232 ELLAAAEK-VYIPMYGEAESLNVGVSSAVVLYEAVRQRHFA 271


>UniRef50_Q4L3J1 Putative trmH family tRNA/rRNA methyltransferase n=10 Tax=Bacilli
           RepID=TRMHL_STAHJ
          Length = 249

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 56/175 (32%), Positives = 89/175 (50%), Gaps = 11/175 (6%)

Query: 3   PTRYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR-- 56
           P  YA   + +  ++        V ++ +  PHN+ +I+RTADA GV  V  + P  R  
Sbjct: 75  PYEYADFDQFIQSQKDKEGLSTVVILDGLEDPHNLGSILRTADASGVDGV--IIPKRRSV 132

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
              +T+A A+ G+   V V     +   +  LK  G  +     +DNA D+R++    P 
Sbjct: 133 ALTQTVAKASTGAIQHVPVMRVTNLAKTIDELKEHGYWVAGAE-ADNATDYRDMAADMPL 191

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
            I++G E  G+++      D  I IPM+G V SLN SVA++L++YE  R+R   G
Sbjct: 192 AIVIGSEGQGMSRLVKDKCDFYIKIPMVGHVNSLNASVAASLMMYEVYRKRHQVG 246


>UniRef50_B0K5F8 RNA methyltransferase, TrmH family, group 3 n=51 Tax=Firmicutes
           RepID=B0K5F8_THEPX
          Length = 247

 Score = 84.7 bits (208), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 46/171 (26%), Positives = 94/171 (54%), Gaps = 11/171 (6%)

Query: 5   RYARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--- 57
           +Y  + ++L     +++    + ++++  PHN+ AIIR+A+A GVH +  + P  R    
Sbjct: 78  KYFEVDDLLEYAEQKKEKPFLLILDEITDPHNLGAIIRSAEAFGVHGI--IIPKRRAVGV 135

Query: 58  -RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
             T+   +AG+   +++     I + +  LK +G+ I+ T ++     F E++Y  P   
Sbjct: 136 NATVVKTSAGAVEHMRIAKVSNINNTIRDLKERGLWIVGTDVNAEK-SFEELNYDFPVAF 194

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           ++G E  G+++  L   D  + IPM G + SLN SVA+++++Y+   +R++
Sbjct: 195 VIGNEGKGVSKLVLQNCDFVVKIPMKGKINSLNASVAASILIYQVVSKRKD 245


>UniRef50_A4A281 Putative rRNA methylase n=1 Tax=Blastopirellula marina DSM 3645
           RepID=A4A281_9PLAN
          Length = 269

 Score = 84.7 bits (208), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 52/147 (35%), Positives = 81/147 (55%), Gaps = 2/147 (1%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHR-T 78
           L V +E V KP N+ AI+RTADAVG   + A    + +    +  A   +   V T   T
Sbjct: 120 LIVVLEGVEKPGNLGAILRTADAVGADCLIAADARTDIFNPNAIRASLGTIFAVPTFEAT 179

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
             + +A L+  G Q+ A  + + AV + +++   PT +++G E  G++   LA    +I 
Sbjct: 180 TAETLAFLRAAGAQMFAARV-EGAVSYEQVELIGPTALILGSEAEGLSDRWLADDVTNIR 238

Query: 139 IPMIGMVQSLNVSVASALILYEAQRQR 165
           +PM G+  SLNVS  +A++LYEA RQR
Sbjct: 239 LPMRGIADSLNVSTTAAVLLYEANRQR 265


>UniRef50_C4V0H0 tRNA/rRNA methyltransferase n=1 Tax=Selenomonas flueggei ATCC 43531
           RepID=C4V0H0_9FIRM
          Length = 272

 Score = 83.6 bits (205), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 54/173 (31%), Positives = 90/173 (52%), Gaps = 13/173 (7%)

Query: 3   PTRYARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEV-----HAVWP 53
           P  Y  + E++A    R +  L + ++ +  P N+ A++RTADA GVH +     H+V  
Sbjct: 99  PVAYVAVEEVIAGARARGEDPLLLLLDGIEDPQNLGALLRTADAAGVHGILLPRRHSV-- 156

Query: 54  GSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
                T+A  +AG+  +V V     I   +  LK QG  I    +    + +   + T  
Sbjct: 157 -PLTETVARVSAGALEYVPVARIGNIAQTIRALKEQGFWIAGADMGGEEI-YDRANLTGA 214

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
             +++G E  G+++    L D  + +PM+G + SLN SVA A+++YEAQRQR+
Sbjct: 215 LVLVIGSEGRGMSRLTRDLCDFTVRLPMMGKINSLNASVAGAILMYEAQRQRR 267


>UniRef50_C8WTZ2 RNA methyltransferase, TrmH family, group 3 n=2
           Tax=Alicyclobacillus acidocaldarius RepID=C8WTZ2_ALIAD
          Length = 255

 Score = 83.6 bits (205), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 54/151 (35%), Positives = 82/151 (54%), Gaps = 9/151 (5%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR-----TMASAAAGSNSWVQVK 74
           L V ++++  PHN  AI+RTA+A G      V  G R +      +A AAAG+   + V 
Sbjct: 108 LVVVLDEIADPHNFGAILRTAEASGAQ---GVVIGKRRQAQVTDVVAKAAAGALETLPVA 164

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
               +  A+  LK  G  I+   + +  V + E+DY  PT +++G E  G+ +      D
Sbjct: 165 RVANVAQALQRLKQAGYWIVGADV-EAKVPYTEVDYRGPTAVVIGSEGQGMRRWVREQCD 223

Query: 135 QDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             + IP++G VQSLN SVA+ ++LYEA RQR
Sbjct: 224 FLVSIPILGRVQSLNASVAAGVLLYEAVRQR 254


>UniRef50_Q06753 Putative trmH family tRNA/rRNA methyltransferase yacO n=86
           Tax=Bacteria RepID=YACO_BACSU
          Length = 249

 Score = 82.8 bits (203), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 52/157 (33%), Positives = 83/157 (52%), Gaps = 8/157 (5%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAAGSNSWVQ 72
           QP   + ++++  PHN+ +I+RTADAVG H +  V P  R      T+A A+ G+   + 
Sbjct: 96  QP-FFLILDELEDPHNLGSIMRTADAVGAHGI--VIPKRRAVGLTTTVAKASTGAIEHIP 152

Query: 73  VKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALAL 132
           V     +   +  +K +G+ ++ T  S    DFR +D   P  +++G E  G+ +     
Sbjct: 153 VARVTNLARTLEEMKERGIWVVGTDASARE-DFRNMDGNMPLALVIGSEGKGMGRLVKEK 211

Query: 133 ADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
            D  I +PM G V SLN SVA+ L++YE  R+R   G
Sbjct: 212 CDFLIKLPMAGKVTSLNASVAAGLLMYEVYRKRNPVG 248


>UniRef50_C0Z9E4 Putative RNA methyltransferase n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0Z9E4_BREBN
          Length = 271

 Score = 82.8 bits (203), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 48/153 (31%), Positives = 84/153 (54%), Gaps = 11/153 (7%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHA------VWPGSRMRTMASAAAGSNSWVQV 73
           L + ++++  P N+  I+RTA+A  +  V        ++ G  +R    A  G+   + V
Sbjct: 124 LLLFLDEIQDPGNLGTILRTAEAAAIDGVVLGSGSVDIYNGKVVR----ATMGALFRIPV 179

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALA 133
            T   + D     K +G ++L + L  N+V + E DY   T +++G E  G+++E  A A
Sbjct: 180 FTQSLV-DTADEWKAKGGRVLISSLEQNSVSYDEADYAGLTALVIGNEGRGVSKEMFAKA 238

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           DQ + IP+ G  +SLN +VA+ + +YEAQR+R+
Sbjct: 239 DQFVHIPLYGGAESLNAAVAAGIFVYEAQRKRR 271


>UniRef50_B2A4B9 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Natranaerobius
           thermophilus JW/NM-WN-LF RepID=B2A4B9_NATTJ
          Length = 247

 Score = 82.4 bits (202), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 59/176 (33%), Positives = 94/176 (53%), Gaps = 16/176 (9%)

Query: 3   PTRYARICEMLA-----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM 57
           P +Y+++  +L       ++P   + ++ +  P N  AIIRTADAVGV  V  + P  R 
Sbjct: 77  PFKYSQLDTVLKGFDYNNQKPLTLLILDHLTDPQNFGAIIRTADAVGVDGV--IIPKRRS 134

Query: 58  ----RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
                T+  A++G+   V +     +   ++ LK Q + IL T +  +   F E +Y  P
Sbjct: 135 VDVNPTVMKASSGAAEHVPIIKVSNLRQTISKLKEQWIWILGTDIDGDRGIFEE-NYNIP 193

Query: 114 TCILMGQEKTGITQEALALADQDII--IPMIGMVQSLNVSVASALILYEAQRQRQN 167
             +++G E +G++   L   + D I  IPMIG V SLN SVA+A++LYE  RQ+ N
Sbjct: 194 LALVVGNEASGMS--PLVKKECDFIANIPMIGRVNSLNASVATAVVLYEIYRQKTN 247


>UniRef50_Q1G8Z2 TRNA/rRNA methyltransferase n=109 Tax=Bacilli RepID=Q1G8Z2_LACDA
          Length = 255

 Score = 82.4 bits (202), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 52/164 (31%), Positives = 85/164 (51%), Gaps = 8/164 (4%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAA 65
           + ++ + L + +  L + ++ +  PHN+ +I+R+ADA GV  V  + P  R   + S  A
Sbjct: 93  FDQLLDKLDQEEAPLLLMLDNIEDPHNLGSILRSADATGVSGV--IIPKRRASGLTSVVA 150

Query: 66  ----GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
               G+   V V     +      LK +G  I  T +  +  D+R+ +    T +++G E
Sbjct: 151 KTSTGAIDHVPVARVNNLVQTCQALKDRGYWIFGTAMEGD--DYRKWNANGKTVLVIGNE 208

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             GI+   L   DQ + IPMIG VQSLN SVA+ ++LY+A   R
Sbjct: 209 GKGISPLLLKQMDQTLTIPMIGHVQSLNASVATGVLLYQAFNSR 252


>UniRef50_UPI0001C31319 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Conexibacter
           woesei DSM 14684 RepID=UPI0001C31319
          Length = 256

 Score = 82.4 bits (202), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 54/168 (32%), Positives = 84/168 (50%), Gaps = 9/168 (5%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MR 58
           P RYA + E+LA   P L V ++++  P N+ AI RTA+  G   +  V P  R      
Sbjct: 92  PFRYAYVDELLAVEHP-LIVALDEIQDPQNLGAIARTAECAGATGL--VIPARRSADVTP 148

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL- 117
            +  A+AG+   + +   R + D +   +G G  +      D  V +  +DY+ P  +L 
Sbjct: 149 AVCKASAGAVEHLPIARARNLADFLGDARGVGAWVYGAE-GDGGVPYTGVDYSGPGVVLV 207

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +G E  G+     A  D  I +P+ G + SLNVS A++ +LYE  RQR
Sbjct: 208 LGSEGRGLRPRVAASCDALIALPLRGRIGSLNVSAAASALLYEIVRQR 255


>UniRef50_A6L4B5 tRNA/rRNA methyltransferase n=16 Tax=Bacteroidetes
           RepID=A6L4B5_BACV8
          Length = 255

 Score = 82.0 bits (201), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 50/151 (33%), Positives = 84/151 (55%), Gaps = 9/151 (5%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA----AGSNSWVQVKT 75
           L V ++ +    N  AI RT +  G   +  + P     ++ + A    AG+   + V  
Sbjct: 98  LFVMLDGITDVRNFGAIARTCECAGADAI--IIPSKNSVSVNADAMKTSAGALHTLPVCR 155

Query: 76  HRTIGDAVAHLKGQGMQILA-THLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
            + + + + +LK  G +I+A T   D   D+ + +Y  P CI+MG E TG+  E L+L D
Sbjct: 156 EQNLTNTIKYLKDCGFKIVAATEKGD--YDYTKANYKDPVCIIMGAEDTGVPYEHLSLCD 213

Query: 135 QDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           + I IP++G ++SLNVSVA+ +++YEA +QR
Sbjct: 214 EWIKIPLMGKIESLNVSVAAGILIYEAVKQR 244


>UniRef50_D2R0C4 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Pirellula staleyi DSM
           6068 RepID=D2R0C4_9PLAN
          Length = 272

 Score = 82.0 bits (201), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 57/160 (35%), Positives = 91/160 (56%), Gaps = 8/160 (5%)

Query: 11  EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR----TMASAAAG 66
           + LA ++  L   +E V KP N+ AI+R+ADA G+  V  +  G+R+         A+ G
Sbjct: 115 DKLAAKRDLLVAVVEGVEKPGNLGAILRSADAAGIDGV--IVCGARLDLYNPNAIRASLG 172

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           +   + V    T+  A+A L+    Q+LAT + D A+D+   D    T I++G E  G++
Sbjct: 173 ALFTLPV-IGMTVPQALAWLRMHQFQMLATRV-DGAIDYTTADLRGRTAIILGSEAEGLS 230

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           +E L    + I +PM+G V SLN+SV +A++ YEA RQR+
Sbjct: 231 REWLGDDIRAISLPMLGTVDSLNLSVTAAILFYEALRQRR 270


>UniRef50_Q488I1 RNA methyltransferase, TrmH family n=1 Tax=Colwellia
           psychrerythraea 34H RepID=Q488I1_COLP3
          Length = 180

 Score = 82.0 bits (201), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 52/165 (31%), Positives = 84/165 (50%), Gaps = 9/165 (5%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM---RT 59
           PTR     E L + +  L V ++ V   +N+ A IR ADA  + +V  +  G+     + 
Sbjct: 17  PTRD----EYLTKPKIPLIVVLDNVTNSYNIGAFIRLADAFAIEKV--IVCGALTISDKK 70

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
           M  A+     WV V+   +   ++  L  +G  I +  L   +VD+ ++ Y     +++G
Sbjct: 71  MKKASRNEAKWVCVEYSDSTTASLQTLLDEGHAIYSVELCHESVDYTKVTYPAKCVLVLG 130

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            E+ G+++ AL L+ Q I IPM GM  SLNVS A A++L E   Q
Sbjct: 131 NERKGVSEAALKLSLQQIHIPMFGMGNSLNVSTAGAIVLAECANQ 175


>UniRef50_D2QM84 RNA methyltransferase, TrmH family, group 3 n=2
           Tax=Flexibacteraceae RepID=D2QM84_9SPHI
          Length = 276

 Score = 82.0 bits (201), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 54/162 (33%), Positives = 87/162 (53%), Gaps = 7/162 (4%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA---- 64
           I ++  R +    + ++++    N  AI RTA+  G+  +  V PG     + S A    
Sbjct: 109 IADVFERGEVPFFLLLDRITDVRNFGAIARTAECTGIQCI--VIPGRGAAAINSDAMKTS 166

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILA-THLSDNAVDFREIDYTRPTCILMGQEKT 123
           +G+ + + V     + + V +L+  G+ ++A T  S   +  R  D T P  I+MG E+ 
Sbjct: 167 SGALNHISVCREPDLTETVKYLQESGITVVACTEKSARDLYERTTDLTGPMAIIMGSEED 226

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           GI+ E L + D  + IP++G V SLNVSVA+ +ILYEA RQR
Sbjct: 227 GISPELLRMVDTHVKIPLLGAVGSLNVSVATGVILYEAVRQR 268


>UniRef50_Q724H1 RNA methyltransferase, TrmH family, group 3 n=21 Tax=Firmicutes
           RepID=Q724H1_LISMF
          Length = 251

 Score = 81.6 bits (200), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 49/156 (31%), Positives = 86/156 (55%), Gaps = 7/156 (4%)

Query: 14  ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAAGSNS 69
           A+ +    + ++++  PHN+ +I+RTAD+VG H +  + P  R     +T+A A+ G+  
Sbjct: 94  AKDEMPFFIILDELEDPHNLGSIMRTADSVGAHGI--IIPKRRSVGLTQTVAKASTGAME 151

Query: 70  WVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEA 129
           +V V     +   +  L+ +G+ I  T  +  + D+R +D   P  I++G E  G++   
Sbjct: 152 YVPVVRVTNMVRTMEELQKRGLWIFGTD-AKGSSDYRTMDVDMPLAIVIGSEGFGMSCLV 210

Query: 130 LALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
               D  + +PM G V SLN SVA++L+LYE  R+R
Sbjct: 211 REKCDFLVHLPMRGKVTSLNASVAASLLLYEVYRKR 246


>UniRef50_C7M4Y5 tRNA/rRNA methyltransferase (SpoU) n=13 Tax=Bacteroidetes
           RepID=C7M4Y5_CAPOD
          Length = 267

 Score = 81.6 bits (200), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 49/150 (32%), Positives = 84/150 (56%), Gaps = 4/150 (2%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTHR 77
           L +  E   KP N+ A++RTADA  +  V    P + +    +  ++ G    V + T  
Sbjct: 118 LLLVAEAPEKPGNIGALLRTADAANIDAVIIANPKTDLYNPNIIRSSVGCVFTVPIATGS 177

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
           T  + +  LK +G+      L+     + E+ +   + I++G E  G+T+E L  + Q+I
Sbjct: 178 T-TEVIDFLKAKGINSYCAALTAFK-PYYEVSFEEASAIVVGTEDQGLTEEWLTHSTQNI 235

Query: 138 IIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           IIPM G++ S+NVSVA+A++++EA+RQR N
Sbjct: 236 IIPMEGVIDSMNVSVAAAVLIFEAKRQRVN 265


>UniRef50_Q8NQN8 rRNA methylases n=1 Tax=Corynebacterium glutamicum
           RepID=Q8NQN8_CORGL
          Length = 198

 Score = 81.3 bits (199), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 52/153 (33%), Positives = 81/153 (52%), Gaps = 9/153 (5%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA----AGSNSWVQ 72
           QP L     +  +P N   +IR +DAVG   V  V+ G  +  + + A    AGS   + 
Sbjct: 43  QPRLVSVPVETREPGNAGTLIRVSDAVGADAV--VFAGESVDPLGAKAVRSSAGSLFHIP 100

Query: 73  VKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREID--YTRPTCILMGQEKTGITQEAL 130
           V  +  I D +  L+ +G+QILAT  +D  VD  + D    +PT  L G E  G+ +  L
Sbjct: 101 VARNNNIADVLGQLRSKGLQILATS-ADGEVDLDDADELLAKPTAWLFGNEAHGLDESLL 159

Query: 131 ALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           A AD  + IP+ G  +SLN++ A+++ LYE+ +
Sbjct: 160 AQADHRVRIPIRGRAESLNLATAASICLYESSK 192


>UniRef50_C2KW83 Possible RNA methyltransferase n=1 Tax=Oribacterium sinus F0268
           RepID=C2KW83_9FIRM
          Length = 260

 Score = 80.9 bits (198), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 48/160 (30%), Positives = 82/160 (51%), Gaps = 11/160 (6%)

Query: 19  DLTVCMEQVHKPHNVSAIIRTADAVGVHEV----HAVWPGSRMRTMASAAAGSNSWVQVK 74
           DL + +E +  P N+  + RTA+A GV+ +    + V P S    +  +  GS   +   
Sbjct: 106 DLFLILENIQDPGNLGTLFRTAEAAGVNHIFLSRNTVDPFSP--KVVRSTMGSLFRLPFS 163

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
               +      LK  G+Q+ A  L      F +  +  P+  L G E  G+T+E    A 
Sbjct: 164 IEEDLFFLCESLKSAGVQVFALDLDGKKTHF-QAAFQGPSAFLFGNEGNGLTKELSQCAT 222

Query: 135 QDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRE 174
           + ++IPM G ++SLNV+ +++++LYEA RQR+    Y++E
Sbjct: 223 EKLLIPMEGKIESLNVATSASIVLYEAVRQRR----YIKE 258


>UniRef50_C8NJ74 rRNA methylase n=38 Tax=Actinomycetales RepID=C8NJ74_COREF
          Length = 272

 Score = 80.5 bits (197), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 53/144 (36%), Positives = 79/144 (54%), Gaps = 9/144 (6%)

Query: 26  QVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR----TMASAAAGSNSWVQVKTHRTIGD 81
           +  +P N   +IR ADAVG   V  V+ G  +      +  A+AGS   V V  +  I D
Sbjct: 125 ETREPGNAGTLIRVADAVGADAV--VFAGETVDPQGPKVVRASAGSLFHVPVARNVNIDD 182

Query: 82  AVAHLKGQGMQILATHLSDNAVDFREID--YTRPTCILMGQEKTGITQEALALADQDIII 139
            +  L+ QG+QILAT  +D  VD  +     +RPT  L G E  G+ +E LA AD  + I
Sbjct: 183 VLGQLRSQGLQILATA-ADGEVDLDDAGELLSRPTAWLFGNEAHGLGEELLAKADHRVRI 241

Query: 140 PMIGMVQSLNVSVASALILYEAQR 163
           P+ G  +SLN++ A+++ LYE+ +
Sbjct: 242 PIRGRAESLNLATAASICLYESSK 265


>UniRef50_B8LD75 Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335
           RepID=B8LD75_THAPS
          Length = 542

 Score = 80.1 bits (196), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 54/182 (29%), Positives = 86/182 (47%), Gaps = 26/182 (14%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMAS 62
           P R  RI E+L +R        E    P NV A +RT D+ G+  V  +      +  A+
Sbjct: 288 PRRLERIDEVLNQRTRHTRFLFENPSNPSNVWACLRTLDSFGIQYVDVIIHSDSYQGKAA 347

Query: 63  --------AAAGSNSWVQVKTHRTIGDAVAHLKGQ-GMQILATHLSDNAVDFRE----ID 109
                    A GS  W+ ++   +I  A+  L+ +    I A+ L+  ++D R+    +D
Sbjct: 348 VNQKRGMRTAMGSACWMTLRQFGSIEAAITSLREEEDCLIYASDLNPASMDVRDLNWDVD 407

Query: 110 YT-------------RPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASAL 156
           Y+             RP CI+MG E+ GI+ +   LAD+   +PM G  +S N+SVA+A+
Sbjct: 408 YSSGGNADSDQQKEQRPICIVMGNEERGISDKMRELADETFYLPMCGFAESFNLSVATAI 467

Query: 157 IL 158
            L
Sbjct: 468 TL 469


>UniRef50_C5NV68 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Gemella
           haemolysans ATCC 10379 RepID=C5NV68_9BACL
          Length = 271

 Score = 80.1 bits (196), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 48/143 (33%), Positives = 79/143 (55%), Gaps = 6/143 (4%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM----RTMASAAAGSNSWVQVKTHR 77
           + ++ +  PHN+ AIIRTA+A GV  +  + P  R     +T   A+AG+   + V    
Sbjct: 125 LILDHIEDPHNLGAIIRTAEASGVKAI--IIPKRRAAVVSQTAVKASAGAIEHMPVIRVS 182

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            + DA+  LK +G  I  T L++ + D+ +I    P  I++G E  G+++      D   
Sbjct: 183 NLTDAIKKLKEKGFWIAGTTLAERSEDYTKIAKDVPLAIVIGNEGEGMSKVVTNECDFLY 242

Query: 138 IIPMIGMVQSLNVSVASALILYE 160
            +PM+G +QSLN SVA+ +I+YE
Sbjct: 243 HLPMLGKIQSLNASVAAGIIMYE 265


>UniRef50_Q1NS81 RNA methyltransferase TrmH, group 3 n=3 Tax=Deltaproteobacteria
           RepID=Q1NS81_9DELT
          Length = 302

 Score = 79.3 bits (194), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 48/153 (31%), Positives = 81/153 (52%), Gaps = 7/153 (4%)

Query: 18  PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR----TMASAAAGSNSWVQV 73
           P L + ++ +  PHN+ A++R+A A GV  V  + P  R      T+  AAAG+ + + +
Sbjct: 145 PPLLLVLDSLQDPHNLGAVLRSAAAFGVDGV--ILPKDRSAPLSGTVLKAAAGTAALLDI 202

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALA 133
                +  A+  LK  G  I      + + +  E D+T PTC+++G E+ GI        
Sbjct: 203 CRTTNLAGALGTLKKHGFWIYGAS-GEASGNLYETDFTGPTCLVLGNEQKGIRPLLKKHC 261

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           D  + IP+   V+SLNVSVA+ ++L E +R++ 
Sbjct: 262 DFLLAIPLAAGVESLNVSVAAGIMLAEIRRRQH 294


>UniRef50_Q1D7V2 RNA methyltransferase, TrmH family, group 3 n=7 Tax=Bacteria
           RepID=Q1D7V2_MYXXD
          Length = 282

 Score = 79.3 bits (194), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 59/177 (33%), Positives = 90/177 (50%), Gaps = 19/177 (10%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           +   +YA + ++L    A  QP L V ++ +  PHN+ AIIR+ADA+G H V  V    R
Sbjct: 107 LRGFKYAELEDLLEAAKALGQPPLVVVLDGIQDPHNLGAIIRSADALGAHGV--VIAKDR 164

Query: 57  ----MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR 112
                 T+A A+AG+    ++     I  A+  LK  G+ + A       VD +E  ++ 
Sbjct: 165 AVQVTGTVAKASAGAVEHSRIARVVNISRALEELKEAGLWVAAAD-----VDAKEPMWSA 219

Query: 113 ----PTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
               P  +++G E  G+    L   D  + IPM G V SLN SV++ ++LYE  RQR
Sbjct: 220 RLDGPLALVVGAEGAGVRDGVLKHCDFRLRIPMAGQVGSLNASVSAGILLYEVARQR 276


>UniRef50_D0B4K6 tRNA/rRNA methyltransferase n=41 Tax=Rhizobiales RepID=D0B4K6_BRUME
          Length = 297

 Score = 79.0 bits (193), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 55/172 (31%), Positives = 88/172 (51%), Gaps = 10/172 (5%)

Query: 2   NPTRYARICEM----LARRQP---DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG 54
           NP   A + E     LA  +P   D+ V +++V  P N+ A+IRTADAVG   V  +   
Sbjct: 119 NPQMVAGVFEQQYHQLAGLKPKGNDVYVALDRVRDPGNLGAVIRTADAVGAKGVILIGDT 178

Query: 55  SRMRTMASAAAGSNSWVQVKTHR-TIGDAVAHLKGQGMQILATHLSDNAVDFREIDY-TR 112
           +   ++ +  A   S   V  +R +  D +   KG    ++ THL   AVD+R I Y  +
Sbjct: 179 TDPYSLETVRATMGSVFSVPLYRASEADFLNWRKGFSGLVVGTHLK-GAVDYRTIPYANK 237

Query: 113 PTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           P  ++MG E+ G+        D+   IP  G   SLN+++A+ ++LYE +R+
Sbjct: 238 PVILIMGNEQQGLPDSLAGACDKLARIPQAGRADSLNLAIATGVMLYEIRRE 289


>UniRef50_A3DH38 RNA methyltransferase, TrmH family, group 3 n=14 Tax=Firmicutes
           RepID=A3DH38_CLOTH
          Length = 277

 Score = 78.2 bits (191), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 50/149 (33%), Positives = 80/149 (53%), Gaps = 7/149 (4%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM----RTMASAAAGSNSWVQVKTHR 77
           + ++ +   +N+ +I+RTADAVG H V  V P  R       ++ A+AG+  +V V    
Sbjct: 131 IILDGITDAYNLGSILRTADAVGAHGV--VIPKRRAIGLNAAVSKASAGAIEYVPVARVT 188

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            I   + +LK + + I+ T LS     F E D   P  +++G E  G+ +      D  +
Sbjct: 189 NISQTIEYLKKKNIWIVGTDLSGEK-PFFEADLKGPVALVIGSEGEGMGRLVSEKCDFIV 247

Query: 138 IIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            IPM G + SLN +VA+A+I+YE +RQR 
Sbjct: 248 NIPMQGKISSLNAAVAAAIIMYEIRRQRN 276


>UniRef50_Q7NYX3 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=23
           Tax=Proteobacteria RepID=RLMB_CHRVO
          Length = 248

 Score = 78.2 bits (191), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 56/169 (33%), Positives = 84/169 (49%), Gaps = 9/169 (5%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           MN      + E L+  +P L + ++ V  PHN+ A +R ADA+G H V A  P  R  T+
Sbjct: 80  MNYVDLDDVLENLS--EPPLLLILDGVTDPHNLGACLRVADAMGAHAVIA--PKDRSATL 135

Query: 61  ----ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
               +  A G+   V   T   +   +  LK  G+ I  T +  +  D    D + P   
Sbjct: 136 NATVSKVACGAAEVVPYITVTNLARTLRDLKDAGVWIAGTTMEAD-TDLYHFDASGPLAW 194

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +MG E  G+ +      D  + IPM G V+SLNVSV+S ++L E++RQR
Sbjct: 195 VMGAEGEGMRRLTREHCDVLVSIPMFGTVESLNVSVSSGMVLSESRRQR 243


>UniRef50_B0P8C0 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0P8C0_9FIRM
          Length = 256

 Score = 77.8 bits (190), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 51/154 (33%), Positives = 79/154 (51%), Gaps = 4/154 (2%)

Query: 14  ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWV 71
           AR +P L V  + +  PHN+ AIIRTA+A G H +     G    T  +   +AG+   +
Sbjct: 102 ARGEPPLLVIADSIEDPHNLGAIIRTAEAAGAHGLIIPKRGGAGLTAIVGRTSAGAVEHL 161

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            V     +   +  LK +G+ I     S    D  + D T P+ +++G E  G+++    
Sbjct: 162 PVARVTNLVSTIKELKARGVWIYGADASGARWD--QTDLTGPSALVIGSEGFGLSRLVRE 219

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             D  + +PM G V SLN SVA+ +++YEA RQR
Sbjct: 220 TCDALLSLPMRGEVNSLNASVAAGILMYEAVRQR 253


>UniRef50_A8RFN1 Putative uncharacterized protein n=2 Tax=Erysipelotrichaceae
           RepID=A8RFN1_9FIRM
          Length = 241

 Score = 77.8 bits (190), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 49/149 (32%), Positives = 77/149 (51%), Gaps = 3/149 (2%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVH-AVWPGSRMR-TMASAAAGSNSWVQVKTHR 77
           L V ++++  PHN+ AI+RT D VGV  V      G ++  T+A  + G+   V+V    
Sbjct: 92  LFVMLDELEDPHNLGAILRTCDCVGVDGVIIGKHRGVKLTPTVAKVSTGAIDTVKVAVVT 151

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            +   +  LK +G  +      DN+ D+R+  Y  P  +++G E  GI+       D  +
Sbjct: 152 NLAQTLKGLKKEGFWVAGADF-DNSQDYRQASYDMPLVLVVGSEGFGISPLVKKNCDFFV 210

Query: 138 IIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            +PM G V SLN SVA A++LY+   QR 
Sbjct: 211 RLPMEGSVSSLNASVACAVLLYQIYAQRN 239


>UniRef50_Q6AJ92 Related to tRNA/rRNA methyltransferase n=1 Tax=Desulfotalea
           psychrophila RepID=Q6AJ92_DESPS
          Length = 295

 Score = 77.8 bits (190), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 54/154 (35%), Positives = 81/154 (52%), Gaps = 11/154 (7%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTA---DAVGV---HEVHAVWPGSRMRTMASAAAGSNSW 70
           +P + VC + +  PHN+ AI+R+A    A+GV    E  A   G    T A ++AG+ S 
Sbjct: 143 KPRIIVC-DSLQDPHNLGAIVRSALASGAIGVLLTRERSAPLGG----TAAKSSAGAISH 197

Query: 71  VQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEAL 130
           + +     +  ++A LK  G  +       +AV   + D   P CI++G E TGI     
Sbjct: 198 MDICQVTNLVKSLAELKKVGAWVFGAIKDADAVSLFDADLNVPACIVVGSEGTGIRPLVR 257

Query: 131 ALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
              D  + IPM+G + SLN SVA+A+IL+EA RQ
Sbjct: 258 RECDIQLSIPMVGELDSLNSSVAAAVILFEAMRQ 291


>UniRef50_C9RBD1 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Ammonifex
           degensii KC4 RepID=C9RBD1_AMMDK
          Length = 254

 Score = 77.4 bits (189), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 56/176 (31%), Positives = 89/176 (50%), Gaps = 11/176 (6%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           ++P  YA + E+LA   P   + +  +  P N+ AI+RTA AVGV  V  + P  R   +
Sbjct: 79  VSPYNYASLDEILAT-HPSCLLVLAYITDPRNLGAILRTAAAVGVEGV--IIPSRRAAGL 135

Query: 61  AS----AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
            +    A+AG    V+V     +   + +LK QG  +L    +D  V   E ++  P  +
Sbjct: 136 TAEALKASAGGAEHVKVARVTNLAQTLRYLKEQGFWVLGAE-ADAKVSLWEAEWNEPLVV 194

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR---QNAG 169
           ++G E TG+ +      D  + IP    +  LN SVA+A+ILYE  R++   +NAG
Sbjct: 195 VIGGEDTGLGKVVRRECDVLVRIPTTAKMPCLNASVAAAVILYEVLRRQMKGKNAG 250


>UniRef50_C7G6D1 RNA methyltransferase, TrmH family n=5 Tax=Clostridiales
           RepID=C7G6D1_9FIRM
          Length = 281

 Score = 77.4 bits (189), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 49/163 (30%), Positives = 81/163 (49%), Gaps = 14/163 (8%)

Query: 11  EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVH-------EVHAVWPGSRMRTMASA 63
           E++   Q  L + +E +  P N+  ++RT +  G+         V    P +   TM   
Sbjct: 125 ELIKGEQTHLLI-LESIQDPGNLGTMVRTGEGAGITGVIMNQTTVDLFNPKTIRSTM--- 180

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
             GS   V     + +   ++ LK Q + + A HL    + + E DY + T  L+G E  
Sbjct: 181 --GSIYRVPFFITKDLAGTISSLKEQQVNVYAAHLK-GTLSYDEPDYKKKTAFLIGNEGN 237

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           G++ E   LAD  I IPM G V+SLN +++++L++YE  RQR+
Sbjct: 238 GLSDEIADLADTYIKIPMQGQVESLNAAISASLLMYETGRQRR 280


>UniRef50_C9LMK8 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Dialister
           invisus DSM 15470 RepID=C9LMK8_9FIRM
          Length = 282

 Score = 77.4 bits (189), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 56/172 (32%), Positives = 88/172 (51%), Gaps = 10/172 (5%)

Query: 1   MNPTRYARICEMLA--RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
           + P  YA + E+L+   R+  L + ++ V    N+ AI+RTA+  G   V  + P  R  
Sbjct: 115 LKPYAYADLEEVLSSCERKDPLLILLDGVEDVRNIGAIVRTAECAGAAAV--LLPKHRSS 172

Query: 59  TMASAA----AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
            + +AA    +G+ +++ V     I   +  LK +G   +   +  +  D  + D   P 
Sbjct: 173 PVTAAAMKTASGAFAYLPVCQIGNIRQTLEKLKERGFWAVGADM--DGGDLYQADLKGPL 230

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            I+MG E  GI+     + D  + IPM G V SLNVSVA+AL++YEA RQR 
Sbjct: 231 VIVMGAEGKGISPLTKRMCDFCVRIPMRGKVSSLNVSVAAALLMYEAVRQRN 282


>UniRef50_B1I0T3 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Clostridia
           RepID=B1I0T3_DESAP
          Length = 251

 Score = 77.4 bits (189), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 56/168 (33%), Positives = 85/168 (50%), Gaps = 8/168 (4%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAA 65
           +A + E+L    P L V +  +  P N+ AI+RTA+A GV    AV P  R   +  AAA
Sbjct: 86  FATVEELLGTENP-LIVVLNAIQDPRNLGAILRTAEAAGVD--GAVVPSRRAAPLTPAAA 142

Query: 66  GSN----SWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
            +      ++ V     I   +   K +G+ ++     D  V + + D   P  +++G E
Sbjct: 143 KTAAGAVEYLPVARVTNIALTLREFKQKGLWVVGAD-PDGPVSYWDADLGGPLALVIGGE 201

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
             G+ +   A  D  + IPM G V SLN SVA+AL++YEA RQR+  G
Sbjct: 202 AGGLGRAVRAECDSLVRIPMSGRVGSLNASVAAALLIYEAVRQRRAGG 249


>UniRef50_Q98R32 TRNA/RRNA METHYLTRANSFERASE n=1 Tax=Mycoplasma pulmonis
           RepID=Q98R32_MYCPU
          Length = 229

 Score = 77.0 bits (188), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 44/162 (27%), Positives = 83/162 (51%), Gaps = 8/162 (4%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           +    +  + +M+  ++  L   ++ +  P+N  AI+R+A+A G+  +  ++P  R   +
Sbjct: 66  LKSLNFVSLDQMIKSKETIL--ILDHLEDPYNFGAILRSANAFGIKNI--IYPIKRAVDI 121

Query: 61  ASAA--AGSNSWVQVKTHRT--IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
            S      S  +V ++ +++  I   +  LK QG  I ++ L   + D  +I +  P+ +
Sbjct: 122 NSTVLKVSSGGFVNLRFYKSNSISATIDKLKKQGYWIYSSSLDPTSEDINKISFNNPSVL 181

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALIL 158
           ++G EK GI+Q     +DQ   I   G VQSLN SVA+ +I 
Sbjct: 182 VIGNEKKGISQTTKKQSDQLFYIKTKGSVQSLNASVAAGIIF 223


>UniRef50_B8C0J2 rRNA methyltransferase (Fragment) n=1 Tax=Thalassiosira pseudonana
           RepID=B8C0J2_THAPS
          Length = 302

 Score = 77.0 bits (188), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 47/145 (32%), Positives = 75/145 (51%), Gaps = 3/145 (2%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKT 75
           R   L + +E+    HN SAI+RTA+A+GV  V+ + P +   T+   AA    W+ V  
Sbjct: 1   RTSRLVIVVERCTNDHNYSAILRTAEALGVQHVYIISPKTINSTLVDEAA--TEWLTVHE 58

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
                + +  L+ +  +I  T LS  A    E +  +   I+ G E  G T E L  AD 
Sbjct: 59  FDDTKECIETLRSENREIWVTDLSQVASCLTE-EGIQKVAIVFGTEAVGCTAEMLNAADL 117

Query: 136 DIIIPMIGMVQSLNVSVASALILYE 160
            + +P+ G   SLN+SVA+AL++++
Sbjct: 118 RVYLPLRGFADSLNLSVATALVVHQ 142


>UniRef50_Q2RFM6 RNA methyltransferase TrmH, group 3 n=2 Tax=Clostridia
           RepID=Q2RFM6_MOOTA
          Length = 246

 Score = 77.0 bits (188), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 53/171 (30%), Positives = 90/171 (52%), Gaps = 11/171 (6%)

Query: 6   YARICEMLARR----QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----M 57
           YA + ++LAR     +P   + +++V  PHN+ AI+R+A+AVG H V  + P  R     
Sbjct: 77  YADLEDLLARAGEAGEPPFLIMLDRVEDPHNLGAILRSAEAVGAHGV--IIPRRRGVGLT 134

Query: 58  RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
             +A AA G+  +V V     +   +  LKG+G+  +     D   +    D+T P  ++
Sbjct: 135 AAVARAAVGAQEYVPVARVTNLARTLEELKGKGLWAIGAA-GDAGQEAFNADFTVPLVLV 193

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           +G E  G++    +  D  + +PM G + SLNV+ A+ +++YE  RQR  A
Sbjct: 194 LGSEGRGLSPLVRSRCDFTVHLPMRGRINSLNVATAATVLMYEVLRQRGQA 244


>UniRef50_A0M5B1 TrmH family tRNA/rRNA methyltransferase n=16 Tax=Bacteroidetes
           RepID=A0M5B1_GRAFK
          Length = 245

 Score = 77.0 bits (188), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 52/148 (35%), Positives = 74/148 (50%), Gaps = 3/148 (2%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSNSWVQVKTHR 77
           L V ++ +    N  AIIRTA+  GV  +     GS          +AG+   + +    
Sbjct: 98  LFVLLDGITDVRNFGAIIRTAECCGVTGIIIQEKGSAPINADTVKTSAGAVFNIPICKVN 157

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            I DAV HL+   ++++A     + V F +ID  +P  I+MG E  GI+   L   D   
Sbjct: 158 HIKDAVFHLQTYDIKLIAATEKTDDVIF-DIDLKQPIAIIMGDEAKGISNSILKSVDYKA 216

Query: 138 IIPMIGMVQSLNVSVASALILYEAQRQR 165
            +PM+G + SLNVSVA    LYEA RQR
Sbjct: 217 KLPMLGSIASLNVSVACGAFLYEAVRQR 244


>UniRef50_B8G1U5 RNA methyltransferase, TrmH family, group 3 n=4 Tax=Firmicutes
           RepID=B8G1U5_DESHD
          Length = 246

 Score = 76.6 bits (187), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 56/174 (32%), Positives = 90/174 (51%), Gaps = 18/174 (10%)

Query: 3   PTRYARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR-- 56
           P  YA + ++LA    + +    + +++V  PHN+ A+IRTADA GVH V  + P  R  
Sbjct: 76  PREYAEVDDILALAGEKGEDPFILVLDEVEDPHNLGALIRTADAAGVHGV--IIPKRRSV 133

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREI---DYT 111
               T+A  +AG+   V V     +G+ V  LK   +Q     +S    +  E+   D T
Sbjct: 134 SLTATVAKTSAGAVEHVLVAR---VGNLVQTLKD--LQKAGCWVSGAEAEGTEVYRSDLT 188

Query: 112 RPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
               I++G E  G+++      D+ + +PM G + SLN SVA ++++YE  RQR
Sbjct: 189 GARVIVIGSEGKGLSRLVKETCDEIVSLPMKGRINSLNASVAGSILMYEVLRQR 242


>UniRef50_D1PXH3 SpoU rRNA methylase n=1 Tax=Prevotella bergensis DSM 17361
           RepID=D1PXH3_9BACT
          Length = 269

 Score = 76.6 bits (187), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 52/147 (35%), Positives = 78/147 (53%), Gaps = 2/147 (1%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTI 79
           L V +E V KP N+ A++R+ADA     V    P + +       +   +   V T    
Sbjct: 121 LIVVLESVEKPGNLGAVLRSADASKADAVIVCNPLTDLFNPNLIRSSIGAIFTVPTVACS 180

Query: 80  GDAVAH-LKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
             A  + LK + ++IL   L D+A  + + D    T I+MG E TG+T      AD  I 
Sbjct: 181 SQACMNFLKERNIKILTAQLQDSA-PYYDSDMRGGTAIVMGTESTGLTDAWRKAADAHIR 239

Query: 139 IPMIGMVQSLNVSVASALILYEAQRQR 165
           IPM+G + SLNVSV++A++++EA RQR
Sbjct: 240 IPMLGQLDSLNVSVSAAILMFEAVRQR 266


>UniRef50_A8SJQ1 Putative uncharacterized protein n=2 Tax=Parvimonas micra ATCC
           33270 RepID=A8SJQ1_9FIRM
          Length = 261

 Score = 76.6 bits (187), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 41/148 (27%), Positives = 77/148 (52%), Gaps = 11/148 (7%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAV-----WPGSRMRTMASAAAGSNSWVQVKTH 76
           +C+E V  P N   IIRTA+A G++++  +     +    +R    A   +N  +  K  
Sbjct: 120 ICLENVSDPGNFGTIIRTANAFGINDILTINCVDKYNSKVLRATMGAIFRTN-IIDCKIE 178

Query: 77  RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQD 136
           +     +  L+  G ++++T LS N+    E  +     ++MG E  GI+ E L +++  
Sbjct: 179 K-----IKELQSGGYRLISTTLSKNSKFLEEFTFDGKNIVVMGNEANGISAEMLKISNNH 233

Query: 137 IIIPMIGMVQSLNVSVASALILYEAQRQ 164
           + I M   ++SLNVS+A+A+I+Y+  + 
Sbjct: 234 LKIDMDNSMESLNVSIAAAIIMYKIFKN 261


>UniRef50_Q8Z0C3 rRNA methylase n=30 Tax=Cyanobacteria RepID=Q8Z0C3_ANASP
          Length = 273

 Score = 76.6 bits (187), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 49/147 (33%), Positives = 80/147 (54%), Gaps = 3/147 (2%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKT--HR 77
           + + +E +  P N+  IIRTA A G   +        +       A +  W ++ T    
Sbjct: 124 VVLALETIQDPGNLGTIIRTAAAAGASGLLLSQDSVDLDNPKVLRASAGQWFRLATAVSE 183

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            +   V   +  GMQ++AT L    + + EID+ +P+ IL+G E  G++ +  A+ADQ++
Sbjct: 184 DLKATVQLCQQAGMQVVAT-LPTAKLTYWEIDWRKPSLILLGNEGAGLSPDLAAMADQEV 242

Query: 138 IIPMIGMVQSLNVSVASALILYEAQRQ 164
            IP+   V+SLNV++ SAL+LYE QRQ
Sbjct: 243 KIPLSPGVESLNVAITSALMLYEVQRQ 269


>UniRef50_C9A4E5 RNA methyltransferase n=3 Tax=Enterococcus casseliflavus
           RepID=C9A4E5_ENTCA
          Length = 259

 Score = 76.3 bits (186), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 45/146 (30%), Positives = 76/146 (52%), Gaps = 11/146 (7%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHA------VWPGSRMRTMASAAAGSNSWVQVKT 75
           + ++ V  P NV  +IRTADA G   V        ++    +R+M     GSN  + +  
Sbjct: 117 LILDNVQDPGNVGTMIRTADAAGFSGVFLGEGTADLYSTKVLRSMQ----GSNYHLPI-V 171

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
              I   +  L+  G+ I  T L+  AV + E+   +    ++G E  G+ QE LAL D+
Sbjct: 172 EGAIPPFLKQLQAAGVAIYGTELNKEAVPYTELPKGQAAAFILGNEGQGVNQELLALTDK 231

Query: 136 DIIIPMIGMVQSLNVSVASALILYEA 161
           ++ IP+ G  +SLNV++A+ +++Y A
Sbjct: 232 NLYIPIYGQAESLNVAIAAGILMYFA 257


>UniRef50_Q6MA83 Putative rRNA methylase n=2 Tax=Chlamydiae/Verrucomicrobia group
           RepID=Q6MA83_PARUW
          Length = 265

 Score = 76.3 bits (186), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 48/146 (32%), Positives = 76/146 (52%), Gaps = 2/146 (1%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIG- 80
           V  E + KP N+  I+R++DAVG+  +      + +       A   +   V T    G 
Sbjct: 118 VVAEAIEKPGNLGTILRSSDAVGIDGLIVCDRCTDIYNPNVVRASVGTLFTVPTVEARGE 177

Query: 81  DAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIP 140
           D +  L  QG+ ILA        +F ++D T P  I +G E+ G+++  +  A   + IP
Sbjct: 178 DILLWLNKQGIDILAAT-PHAEKEFTQVDLTSPVAIAVGTEQLGLSERWMKQATMQVRIP 236

Query: 141 MIGMVQSLNVSVASALILYEAQRQRQ 166
           M+G+  SLNV++A+ L+LYE  RQRQ
Sbjct: 237 MMGVADSLNVAMATTLLLYEVLRQRQ 262


>UniRef50_B9ZJH8 RNA methyltransferase, TrmH family, group 3 n=1
           Tax=Thioalkalivibrio sp. K90mix RepID=B9ZJH8_9GAMM
          Length = 251

 Score = 76.3 bits (186), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 55/154 (35%), Positives = 77/154 (50%), Gaps = 11/154 (7%)

Query: 19  DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA----AGSNSWVQVK 74
           DL + ++ V  PHN+ A +RTADA G   +  V P      +  AA    +G+   V V 
Sbjct: 102 DLVLVLDGVTDPHNLGACLRTADAAGAGAI--VTPRHHSAALTPAAIKVASGAAETVPVV 159

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAV--DFREIDYTRPTCILMGQEKTGITQEALAL 132
               +   +A LK  GM  +     D A   D   +D   PT I+MG E  G+ +     
Sbjct: 160 AVGNLARTLAALKDAGMWTVGL---DGAAHEDLYAVDLRPPTAIVMGAEGEGMRRLTREA 216

Query: 133 ADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            D    IPM G V+SLNVSVA+ + L+EA+RQR+
Sbjct: 217 CDHLARIPMGGTVESLNVSVATGITLFEARRQRR 250


>UniRef50_Q4A651 Putative tRNA/rRNA methyltransferase n=1 Tax=Mycoplasma synoviae 53
           RepID=Q4A651_MYCS5
          Length = 233

 Score = 75.9 bits (185), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 40/152 (26%), Positives = 79/152 (51%), Gaps = 6/152 (3%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA--AGSNSWVQVK 74
           +P + + ++ +   +N+ AIIR+A+A G+ ++  V P      + S      S  ++ + 
Sbjct: 81  KPKIVLVLDHIMDTYNLGAIIRSANAAGIKDI--VMPKENCADITSNVLKVSSGGFIGIN 138

Query: 75  THR--TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALAL 132
            ++  ++   +  LK     I  + L  N+  +    Y  P   ++G E+ GI++ AL  
Sbjct: 139 FYKVSSLNAFLNKLKKHSYWIYGSMLDKNSTSYYSAKYNFPMAFILGNEEKGISKSALVE 198

Query: 133 ADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            D+ I IP  G V+SLNVSVA+ ++L++ + +
Sbjct: 199 VDEKIHIPQSGSVESLNVSVAAGILLFDIKHK 230


>UniRef50_Q11YB9 tRNA/rRNA methyltransferase, TrmH family n=24 Tax=Bacteroidetes
           RepID=Q11YB9_CYTH3
          Length = 268

 Score = 75.9 bits (185), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 48/148 (32%), Positives = 77/148 (52%), Gaps = 3/148 (2%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRT- 78
           L V +++V    N  A+ R+A+ +GV  +     G+      +    + +   +   R  
Sbjct: 116 LLVMLDRVTDVRNFGAVARSAECLGVDAMIVPSRGAAQLNSDAVKTSAGALYHIPVCRVD 175

Query: 79  -IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            + D V +LK  G++I+A      +++  + D T P  ILMG E+ GI+ + L  AD  +
Sbjct: 176 HLIDTVKYLKQCGLRIIACS-EKASINVYDEDLTDPCVILMGSEEDGISMDLLRYADAHV 234

Query: 138 IIPMIGMVQSLNVSVASALILYEAQRQR 165
            IPM G + SLNVSVA+ +IL E  RQR
Sbjct: 235 TIPMSGHINSLNVSVATGMILSEVTRQR 262


>UniRef50_B6YR56 23S rRNA (Guanosine-2'-O-)-methyltransferase n=1 Tax=Candidatus
           Azobacteroides pseudotrichonymphae genomovar. CFP2
           RepID=B6YR56_AZOPC
          Length = 274

 Score = 75.9 bits (185), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 49/151 (32%), Positives = 81/151 (53%), Gaps = 8/151 (5%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT----MASAAAGSNSWVQVKT 75
           L + +E + KP N+ AI+RTA+A  +       P + +       +S     ++ + V +
Sbjct: 125 LIIVLESIEKPGNLGAILRTAEAAKIDATIICNPSTDIYNPNVVRSSIGCLFSNPIAVAS 184

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
           +    + +A+LK + +QI A  L+     +   D+T  + I++G E  G+T   L  A Q
Sbjct: 185 NE---ETLAYLKSKSVQIFAAELTAFK-QYYNTDFTSASAIVIGAEVNGLTNFWLDNAHQ 240

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            I IPM G++ SLNVSV+ A+I +EA RQR 
Sbjct: 241 RIKIPMQGIIDSLNVSVSVAIITFEAIRQRN 271


>UniRef50_Q83CW6 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=19
           Tax=Proteobacteria RepID=RLMB_COXBU
          Length = 250

 Score = 75.9 bits (185), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 55/158 (34%), Positives = 82/158 (51%), Gaps = 11/158 (6%)

Query: 15  RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEV-----HAVWPGSRMRTMASAAAGSNS 69
           R  P L + ++ V  PHN+ A +R+A+A GV  V      AV     +R +A  AA    
Sbjct: 93  RETPALLLILDGVKDPHNLGACLRSANAFGVRAVIAPKDRAVGVTPVVRKVACGAAEMTP 152

Query: 70  WVQVKT-HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQE 128
           +++V    RTI      L+ +G+ I+ T +    +  +EID T    I++G E  G+ + 
Sbjct: 153 FIRVTNLSRTID----WLQKEGVWIVGTAVEAETL-IQEIDLTGDIAIVLGSEGAGLRRL 207

Query: 129 ALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
                D    IP+ G V+SLNVSVA  + LYE QRQR+
Sbjct: 208 TKERCDFLAQIPLRGSVESLNVSVACGICLYEVQRQRE 245


>UniRef50_Q1ISZ4 RNA methyltransferase TrmH, group 3 n=2 Tax=Acidobacteria
           RepID=Q1ISZ4_ACIBL
          Length = 261

 Score = 75.9 bits (185), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 49/152 (32%), Positives = 75/152 (49%), Gaps = 8/152 (5%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAAGSNSWVQVKT 75
             V ++ +  PHN+ A+IR+AD  GV  V  V P  R      T   A+AG+  +V +  
Sbjct: 94  FVVVLDGIEDPHNLGALIRSADGAGVDGV--VIPERRAVGVTGTAMKASAGAAEYVPIAR 151

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAV-DFREIDYTRPTCILMGQEKTGITQEALALAD 134
              I  ++  LK +   +    L +    ++ EIDY     +++G E  G+        D
Sbjct: 152 VTNIARSIEDLKDK-YNVWTVGLDERGTQNYDEIDYNMSLALVLGAEGKGLHDLVRKKCD 210

Query: 135 QDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
             + IPM G V SLNVSVA  +++YE  RQR+
Sbjct: 211 LLVKIPMAGEVSSLNVSVAGGIVMYEVSRQRR 242


>UniRef50_B4U792 RNA methyltransferase, TrmH family, group 3 n=9 Tax=Aquificales
           RepID=B4U792_HYDS0
          Length = 251

 Score = 75.5 bits (184), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 47/175 (26%), Positives = 83/175 (47%), Gaps = 10/175 (5%)

Query: 1   MNPTRYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
           ++P  Y    E+  +   +    V ++ +  P NV +I RT +  G   +  + P  R  
Sbjct: 77  LSPITYVPEEELFRKTIEEKGFFVVLDHITDPQNVGSIARTVEVFG--GIGLLIPKDRSA 134

Query: 59  TMASAAAGSNSW----VQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
            + +    S+S     +++    +I  A+   K  G  + A  L     D  ++D+  P 
Sbjct: 135 PINAVVVKSSSGAIFHLKISKTPSISKAIKTFKEMGGWVYA--LEKGGKDITKVDFAYPM 192

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
           CI++G E  G+++  L  +D  + IPM G V SLNVS A A+ L+E  + ++N G
Sbjct: 193 CIVLGSEGEGVSKNVLEHSDVRVSIPMKGKVTSLNVSAAGAICLWEVYKNQENTG 247


>UniRef50_Q9JZR3 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=27
           Tax=Neisseria RepID=RLMB_NEIMB
          Length = 250

 Score = 75.5 bits (184), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 49/151 (32%), Positives = 78/151 (51%), Gaps = 3/151 (1%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSNSWVQVK 74
           +P L + ++ +  PHN+ A +RTADA+GVH V A    S     T++  A G+   V   
Sbjct: 94  EPPLLLILDGITDPHNLGACLRTADAMGVHAVIAPKDKSAGLNATVSKVACGAAETVPYI 153

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
           T   +   +  LK  G+ I+ T +S  + D    +       +MG E  G+ +      D
Sbjct: 154 TVTNLARTLRELKEYGIWIIGTDMSGES-DLYHCNLPDSAAWVMGNEGDGMRRLTREHCD 212

Query: 135 QDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             + IPM G V+S+NVSV++ ++L E +RQR
Sbjct: 213 MLVSIPMFGTVESMNVSVSAGMVLSETRRQR 243


>UniRef50_Q7MH13 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=32
           Tax=Proteobacteria RepID=RLMB_VIBVY
          Length = 247

 Score = 75.5 bits (184), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 54/159 (33%), Positives = 80/159 (50%), Gaps = 7/159 (4%)

Query: 11  EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAAG 66
           ++LA+    L + ++ V  PHN+ A +R ADA GV  V  + P  +      T++  A G
Sbjct: 88  DILAKHASPLLLILDGVTDPHNLGACLRNADAAGVAAV--IVPKDKSAPMTATVSKVACG 145

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           +   V +     +   + HL+ QG+ I+ T   +   D  +   T    I+MG E  G+ 
Sbjct: 146 AAETVPLVRVTNLARTMRHLQEQGIWIVGTA-GEATHDIYQAKLTGSLAIVMGAEGDGMR 204

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +      D  I IPM G V SLNVSVAS + L+EA RQR
Sbjct: 205 RLTRETCDDLIKIPMAGAVSSLNVSVASGICLFEAVRQR 243


>UniRef50_A0LZG1 TrmH family tRNA/rRNA methyltransferase n=7 Tax=Flavobacteria
           RepID=A0LZG1_GRAFK
          Length = 273

 Score = 75.5 bits (184), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 58/171 (33%), Positives = 93/171 (54%), Gaps = 11/171 (6%)

Query: 10  CEMLARRQP-DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAG 66
            E L+   P  L +  E   KP N+ AI+RTADA  V  V    P + +    +  ++ G
Sbjct: 110 VENLSFEHPFPLILVAEAPEKPGNIGAILRTADAAAVDAVIIANPKTDLYNPNIIRSSVG 169

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           S    ++ T  T  + +  L+ Q + I A  L  +   + +I++   + I+MG E TG++
Sbjct: 170 SLFTNKIATG-TTSEIIQFLQAQKIHIYAAALQASK-PYSDINFKEASAIIMGTEATGLS 227

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSM 177
            E L  + Q+IIIPM G + S+NVSVA+ ++++EA+RQR      L ENS+
Sbjct: 228 NEWLENSTQNIIIPMHGKIDSMNVSVAAGILIFEAKRQR------LVENSL 272


>UniRef50_C4G1K9 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
           49176 RepID=C4G1K9_ABIDE
          Length = 279

 Score = 75.5 bits (184), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 47/146 (32%), Positives = 75/146 (51%), Gaps = 13/146 (8%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVH-------EVHAVWPGSRMRTMASAAAGSNSWVQVK 74
           + +E    P N+  I+RTA+A GV         V    P     TM S      ++V+  
Sbjct: 139 LVLEDTADPGNLGTIMRTAEAAGVTGVIMGKGTVDIFNPKVVRSTMGSIFRLPFTYVE-- 196

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
               + + +  LK  G+   ATHL      +++I Y+  + I++G E  G++ E   LAD
Sbjct: 197 ---DLKETIKELKKSGISFYATHLKGEK-SYKDIKYSGRSAIIVGNEARGLSDEVADLAD 252

Query: 135 QDIIIPMIGMVQSLNVSVASALILYE 160
             ++IPM G V+SLN +VA+AL++YE
Sbjct: 253 TYVLIPMQGKVESLNAAVAAALMMYE 278


>UniRef50_Q2ST10 RNA methyltransferase, TrmH family, group 3 n=5 Tax=Mollicutes
           RepID=Q2ST10_MYCCT
          Length = 244

 Score = 75.5 bits (184), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 38/162 (23%), Positives = 83/162 (51%), Gaps = 4/162 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR-- 58
            N T +  +   L  ++  L + ++Q+H P+N  AIIR+   + V  +  +    +++  
Sbjct: 74  FNYTPFDELLNDLNTKEKSLVLVLDQIHDPYNFGAIIRSCSLLNVDGI-IILDKKQVQVN 132

Query: 59  -TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
            T+   ++GS   +++     + +A+  LK  G  I AT+L+ N+ D  +  +   + ++
Sbjct: 133 STVLKTSSGSAFDIKISKTNNLNNAIKILKNNGFWIYATNLNQNSTDMTKTQFANKSVVI 192

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILY 159
           +G E+ G+++     +D +I +P    + S N SVA ++I +
Sbjct: 193 IGNEQKGVSELLTKNSDFNIYVPSNKNIDSFNASVACSIICF 234


>UniRef50_Q73MR5 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Treponema
           denticola RepID=Q73MR5_TREDE
          Length = 258

 Score = 74.7 bits (182), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 44/158 (27%), Positives = 79/158 (50%), Gaps = 8/158 (5%)

Query: 13  LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAAGSN 68
           LA +     V ++ V  PHN  +IIR+AD  G+  +  + P ++       ++  +AG+ 
Sbjct: 104 LAEKGSAFVVILDSVTDPHNTGSIIRSADQFGIDGI--IVPENKSAGGFEIISKVSAGAL 161

Query: 69  SWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQE 128
           +WV       +   V  LK +G  I        A+    + + + T ++MG E  G+++ 
Sbjct: 162 AWVPFVEVTNLVRTVERLKKEGFWIYGADAGGKALP--NLTFPKKTVLIMGNEGRGMSRL 219

Query: 129 ALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
                D+ + IP  G + SLNVSVA+ ++LYE  R+++
Sbjct: 220 VEETCDEIVSIPTKGKLDSLNVSVAAGILLYEISRKKE 257


>UniRef50_D1CEQ6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Thermobaculum terrenum
           ATCC BAA-798 RepID=D1CEQ6_THET1
          Length = 180

 Score = 74.7 bits (182), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 44/157 (28%), Positives = 74/157 (47%), Gaps = 2/157 (1%)

Query: 15  RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEV--HAVWPGSRMRTMASAAAGSNSWVQ 72
           R + DL   ++ +  P NV A  R AD     E+      P     T+A    G++  + 
Sbjct: 24  RPEVDLVFLLQDLEDPVNVGAAFRIADGCEASEIILTGKTPTPPDSTIAGVGRGAHRRIP 83

Query: 73  VKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALAL 132
            +      +A+  LKG G    A  +++ AV +  + Y    C+++G E  G+T   L++
Sbjct: 84  WRYVEHADEALVELKGMGYMACAIEVAEGAVPYYSLKYPDRVCLVVGHEYHGVTTRTLSV 143

Query: 133 ADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
            D  + IPM G ++SLNV VA A++ +    Q+   G
Sbjct: 144 CDNAVYIPMYGKIKSLNVHVALAVVAFHVLHQQLICG 180


>UniRef50_A9BJB6 RNA methyltransferase, TrmH family, group 3 n=3 Tax=Thermotogaceae
           RepID=A9BJB6_PETMO
          Length = 240

 Score = 74.7 bits (182), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 44/168 (26%), Positives = 83/168 (49%), Gaps = 9/168 (5%)

Query: 2   NPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----M 57
           N  +Y  + +++  ++    V ++Q+  PHN  AI+RT+ A GV  +  + P        
Sbjct: 74  NDFKYENL-DIIEGKEKLFLVILDQIQDPHNFGAIVRTSVAAGVDAI--IIPKDNAVEVT 130

Query: 58  RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
             +   ++G    + +     + + +  LK + + +    +      + EID+    C++
Sbjct: 131 PVVIKVSSGQIFKIPIIKVTNLSNTIETLKKENVWVYGADVEGKP--YYEIDWQGKICLV 188

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            G E  GI +      D+ + IPM   V+SLNVSV+S +IL+EA++QR
Sbjct: 189 FGNEGNGIRKNVKNHCDELVSIPMFNNVESLNVSVSSGIILFEAKKQR 236


>UniRef50_B2V596 RNA methyltransferase, TrmH family n=7 Tax=Clostridium
           RepID=B2V596_CLOBA
          Length = 262

 Score = 74.7 bits (182), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 52/170 (30%), Positives = 88/170 (51%), Gaps = 10/170 (5%)

Query: 2   NPTRYARICEMLARR---QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS--- 55
           NP     I +M  ++   Q D  +  ++V  P N+  IIRTA A GV+ +  +  G+   
Sbjct: 91  NPQGIIAIVKMNNKKLDFQGDFYLFCDKVQDPGNLGTIIRTAHAAGVNGI-VLSKGTVDI 149

Query: 56  -RMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
              +T+ S   GS  ++ +         +  LK  G  ++ T L +++ DF + D     
Sbjct: 150 YNEKTIRSTM-GSLFYMPIYYDDDEFSLIKSLKKDGFTLIVTSL-ESSKDFFKEDLKGKI 207

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            + +G E  G++ E L LAD+ + IPM G  +SLNV++A+++I+YE  RQ
Sbjct: 208 ILTVGNEGNGVSNEVLDLADRRVKIPMPGGAESLNVAIATSIIIYEKVRQ 257


>UniRef50_A2U0X8 SpoU rRNA methylase family protein n=2 Tax=Polaribacter
           RepID=A2U0X8_9FLAO
          Length = 171

 Score = 74.7 bits (182), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 39/149 (26%), Positives = 76/149 (51%), Gaps = 6/149 (4%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEV--HAVWPGSRMRTMASAAAGSNSWVQVKTHR 77
           +T+  + +  P N+    R +++ GV ++  H   P    R + + A  + + ++ +T+ 
Sbjct: 18  ITIVCDAIRTPENIGMCFRISESFGVEKIYFHENSPSIENRKVINTARNTINQIEYQTYS 77

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR--PTCILMGQEKTGITQEALALADQ 135
                +  LK +G  I+   ++D ++D ++ D+ +     +L+G E+ GI  E + L D+
Sbjct: 78  EFDQLIQELKQKGNTIIGIEITDKSIDIQDFDFKKYEKIVLLLGSERNGI--ENINLVDE 135

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            I IPM G   S+NV  + A+ LYE   Q
Sbjct: 136 TIAIPMYGRNSSMNVIHSLAITLYEITNQ 164


>UniRef50_Q82XD1 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=112
           Tax=Proteobacteria RepID=RLMB_NITEU
          Length = 260

 Score = 74.3 bits (181), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 55/174 (31%), Positives = 86/174 (49%), Gaps = 11/174 (6%)

Query: 5   RYARICEML-ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM----RT 59
           RYA + ++L    +P L + ++ V  PHN+ A +R ADA GVH V  V P  R      T
Sbjct: 81  RYATLEDLLEGLTEPALLLVLDGVKDPHNLGACLRVADAFGVHAV--VVPKDRAVGLSAT 138

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
           +   A+G+   V       +   +  LK  G+ I+ T  +D       +  TRP   ++G
Sbjct: 139 VHKVASGAVDTVPFFAVTNLARTLRELKEMGLWIVGT-AADAPDTLDSVTLTRPLAWVLG 197

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR---QRQNAGM 170
            E  G+ +      D  + IPM G ++SLNVSV++ + L+E  R   QR  +G+
Sbjct: 198 AEDGGMRRLTREACDLLVSIPMSGSIESLNVSVSAGICLFETFRQHSQRTGSGL 251


>UniRef50_Q2JI19 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Synechococcus
           RepID=Q2JI19_SYNJB
          Length = 378

 Score = 74.3 bits (181), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 56/172 (32%), Positives = 88/172 (51%), Gaps = 11/172 (6%)

Query: 2   NPTRYARICEMLAR-RQ--PD-LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
            P +Y  + +++ R RQ  P+ + V ++ +  PHN+ AI R+ +A G+  +  V P  R 
Sbjct: 178 TPYQYVALEDLVERSRQAGPNPVLVVLDGIQDPHNLGAIARSVEAFGMQGM--VIPQRRA 235

Query: 57  ---MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
                T+   AAG+ S + V     +  A+ +LK QG  +  T  S  A      D+ RP
Sbjct: 236 AGVTSTVMKVAAGALSTLPVARVVNLNRALEYLKEQGFWVYGT-TSRGADPIYSADFQRP 294

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             +++G E  GI+       DQ + IP+ G  +SLN SVA+ + LYE  RQR
Sbjct: 295 IALVVGSEGEGISLLTQRHCDQLLSIPLAGRTESLNASVAAGIALYEIHRQR 346


>UniRef50_C0BJH2 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Flavobacteria bacterium
           MS024-2A RepID=C0BJH2_9BACT
          Length = 264

 Score = 74.3 bits (181), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 45/156 (28%), Positives = 81/156 (51%), Gaps = 3/156 (1%)

Query: 13  LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMAS--AAAGSNSW 70
           L   +  + + +E   KP N+ A+ RTA A  +  V    P +      S  ++ G    
Sbjct: 108 LKLNKNSIVLVIEAPEKPGNIGALYRTAAAAKIDAVIIANPKTDFYNPNSIRSSLGGIFI 167

Query: 71  VQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEAL 130
           +      +I + +A+LK   + I    ++  AV + + +YT P  ++MG E TG+ Q  L
Sbjct: 168 LPTAIASSI-EVIAYLKENKITIATAAINSKAVPYDQFEYTPPCALVMGTESTGLDQLWL 226

Query: 131 ALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
              +Q+++IPM   V SLN+SV++ +++YE QR+ +
Sbjct: 227 NETNQNLMIPMADEVDSLNLSVSAGILMYECQRKNK 262


>UniRef50_A5UYW3 RNA methyltransferase, TrmH family, group 3 n=4 Tax=Chloroflexi
           (class) RepID=A5UYW3_ROSS1
          Length = 252

 Score = 74.3 bits (181), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 45/163 (27%), Positives = 82/163 (50%), Gaps = 8/163 (4%)

Query: 10  CEMLA--RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGS 67
           C  LA  R +P   + ++ +  P NV  ++RTA+ VGVH V  V PG R   +  A   +
Sbjct: 86  CLALAEERGEPAFLLLLDHIQDPQNVGTLLRTAEVVGVHGV--VIPGRRAAEVTPAVVNT 143

Query: 68  NSW----VQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           +S     ++V     +   +  ++  G+ ++     + A ++  +D   P  +++G E  
Sbjct: 144 SSGAVEHLRVAVVTNLAATIEQIQHAGVWVVGVEDDERAYEYDRVDLDLPLALVLGAEGP 203

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           G+ +      D  + +PM G + SLNV+VA +++LY A R R+
Sbjct: 204 GLARLTRERCDFLVRLPMRGQIASLNVAVAGSIVLYHAWRVRE 246


>UniRef50_Q1LSR1 RNA methyltransferase, TrmH family, group 3 n=4
           Tax=Gammaproteobacteria RepID=Q1LSR1_BAUCH
          Length = 248

 Score = 73.9 bits (180), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 48/160 (30%), Positives = 84/160 (52%), Gaps = 9/160 (5%)

Query: 12  MLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEV-----HAVWPGSRMRTMASAAAG 66
           +LA+    L + ++ V  PHN+ A +R ADA GV+ +      + +  + ++ +AS AA 
Sbjct: 89  LLAQHTAPLLLVLDGVTDPHNLGACLRCADAAGVNAIIIPRNRSAYLNATVKKVASGAAE 148

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHL-SDNAVDFREIDYTRPTCILMGQEKTGI 125
           +   +QV     +   +  L+   + IL T + +D+ +      +T P  +++G E  GI
Sbjct: 149 TMPLIQVTN---LARTLRLLQEHNILILGTTIEADSHIYQTSFKFTSPIALVVGAEGNGI 205

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            +      ++ + IPM+G V SLNVSVA  + L+E  RQR
Sbjct: 206 RRLTKKYCNELLRIPMVGSVASLNVSVAVGVFLFEVVRQR 245


>UniRef50_D0NTV0 SpoU rRNA Methylase family n=17 Tax=Phytophthora infestans T30-4
            RepID=D0NTV0_PHYIN
          Length = 1346

 Score = 73.9 bits (180), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 51/162 (31%), Positives = 84/162 (51%), Gaps = 11/162 (6%)

Query: 16   RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR----TMASAAAGSNSWV 71
            RQP L +C   V K  N++ + RT +     ++  V P  RM     T  + +A ++ W+
Sbjct: 1182 RQP-LIMCASLVDKVPNLAGLARTCEIFNAQKL--VVPNLRMTQQDVTFVNVSATAHKWM 1238

Query: 72   QVKTHRTIGD----AVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQ 127
             ++  R  GD    A+   K +G  I+A   + ++V        R   +++G+EK GI  
Sbjct: 1239 PLEEVRPQGDDLRRALVRWKREGYTIVAVEQTASSVSLASYTLPRKMVLVLGREKEGIPV 1298

Query: 128  EALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
            E L L D  + IP  G+V+SLNV V+ AL+L+E  +Q+  +G
Sbjct: 1299 EVLQLVDVCVEIPQFGLVRSLNVHVSGALVLWEYTQQQLMSG 1340


>UniRef50_A8S2F6 Putative uncharacterized protein n=8 Tax=Clostridiales
           RepID=A8S2F6_9CLOT
          Length = 270

 Score = 73.9 bits (180), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 43/153 (28%), Positives = 80/153 (52%), Gaps = 11/153 (7%)

Query: 24  MEQVHKPHNVSAIIRTADAVGV------HEVHAVWPGSRMRTMASAAAGSNSWVQVKTHR 77
           +E +  P N+  IIR  +  G+      H+   ++    +R+      GS   +      
Sbjct: 118 LETIQDPGNLGTIIRAGEGAGITGIVMNHDTADIYNPKVIRS----TMGSIFRMPFVYAD 173

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            + DA   +K +G+++ A HL     ++ + DYT     L+G E  G+T+E  +LAD  +
Sbjct: 174 DLQDACLLMKNRGVRLFAAHLK-GMNNYDQEDYTDNVGFLIGNEANGLTEETTSLADCLV 232

Query: 138 IIPMIGMVQSLNVSVASALILYEAQRQRQNAGM 170
            IPM G V+SLN ++A++++++E  RQR++  +
Sbjct: 233 KIPMEGKVESLNAAIAASVLMFETARQRRSCSV 265


>UniRef50_B8D0A6 RNA methyltransferase n=11 Tax=Firmicutes RepID=B8D0A6_HALOH
          Length = 244

 Score = 73.9 bits (180), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 47/152 (30%), Positives = 78/152 (51%), Gaps = 7/152 (4%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAAGSNSWVQVKT 75
             + ++QV  PHN+ AIIRTA A G H +  ++P  R       +  A+AG+ + + +  
Sbjct: 95  FIIILDQVQDPHNLGAIIRTAYAAGAHGL--IYPRKRSADITPVVTKASAGAVNHLPLAK 152

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
              I   +A LK  G+ I  T +      +   DY  P  +++G E  G+ +      D 
Sbjct: 153 VSNINYTIADLKDMGLWITGTDVRGTR-PYYSADYKGPVGLVIGNEGKGMRRLVKENCDF 211

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
            + IPM G + SLN SVA+ ++++E  RQR++
Sbjct: 212 VVNIPMSGELGSLNASVAAGVVIFEVVRQRRS 243


>UniRef50_B1AIB3 RNA methyltransferase, TrmH family, group 3 n=15 Tax=Ureaplasma
           RepID=B1AIB3_UREP2
          Length = 239

 Score = 73.9 bits (180), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 43/160 (26%), Positives = 81/160 (50%), Gaps = 7/160 (4%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP----GSRMR 58
            T      +++  ++  L + ++++  P N  AIIRTA+  GV  +  ++      S   
Sbjct: 74  KTSLESFLKLIKDKKNALVLILDEIEDPRNFGAIIRTANGFGVDAI--IYKKHHQASIND 131

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
            +   + G+ +++ +     + + + +L+ +G  + AT L  +   + ++DY   T  ++
Sbjct: 132 LVIKTSMGAINYIYMIEVNNLSNTIKNLQDEGFWVYATSLLKSQ-PYEKVDYANKTVFIV 190

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALIL 158
           G E  G++   L  ADQ I I M G VQSLNV VA+ +IL
Sbjct: 191 GNENKGVSPLILKNADQSIRIDMFGDVQSLNVGVATGIIL 230


>UniRef50_C6CVT7 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Bacillales
           RepID=C6CVT7_PAESJ
          Length = 264

 Score = 73.9 bits (180), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 52/165 (31%), Positives = 78/165 (47%), Gaps = 28/165 (16%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKT 75
           R   L V ++ V  P NV  IIR+ADAVG   V                 GS      KT
Sbjct: 112 RNNSLVVVLDGVRDPGNVGTIIRSADAVGADAV-------------VLGKGSVDLYNPKT 158

Query: 76  HRTIGDAVAHL--------------KGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
            R+   ++ HL              + +G++++ T L      +   D+T  T +LMG E
Sbjct: 159 VRSTMGSLFHLPIIEADLAELLPEAQSKGIKLVGTSLQATHTCYT-YDWTAGTWLLMGNE 217

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
             G++       D+ +IIPM G  +SLNV++A+ ++LYEA RQR+
Sbjct: 218 SEGLSDAVRLAVDESVIIPMQGEAESLNVAMAATVLLYEAVRQRK 262


>UniRef50_C4Z380 RNA methyltransferase, TrmH family n=1 Tax=Eubacterium eligens ATCC
           27750 RepID=C4Z380_EUBE2
          Length = 279

 Score = 73.9 bits (180), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 53/166 (31%), Positives = 77/166 (46%), Gaps = 15/166 (9%)

Query: 7   ARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGV-------HEVHAVWPGSRMRT 59
           + I +ML      L + +E +  P N+  I+R  +  GV       + V    P +   T
Sbjct: 120 SSISDMLTDNP--LLILVENLQDPGNLGTILRMGEGAGVTGVIMSSNTVDIYNPKTIRST 177

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
           M S       +VQ        DAV+  K  G+++ A HL        E DY   T  L+G
Sbjct: 178 MGSIFRVPFVYVQ-----DFSDAVSQCKNAGIKVYAAHLDGKNTYLGE-DYREGTAFLIG 231

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            E  G+T++    AD  I IPM G V+SLN ++A  ++ YEA RQR
Sbjct: 232 NEGNGLTEDITKQADTLIRIPMQGEVESLNAAIACTILTYEAVRQR 277


>UniRef50_Q2JVF6 RNA methyltransferase, TrmH family n=2 Tax=Synechococcus
           RepID=Q2JVF6_SYNJA
          Length = 270

 Score = 73.6 bits (179), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 50/154 (32%), Positives = 80/154 (51%), Gaps = 12/154 (7%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVH----EVHAVWPGSRMRTMASAAAGSNSWVQVKT 75
           L + +E +  P N+ ++IR   A G         +V P +     ASA      W + + 
Sbjct: 115 LGLVVETLQDPGNLGSLIRVVAATGADGLWLSADSVDPENPKVLRASA----GQWFR-RP 169

Query: 76  HRTIGDAVAHLKG---QGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALAL 132
            + + D  A ++    QG+Q+LA  L+  A  + + D TRPT  L+G E  G+ +  + L
Sbjct: 170 PQVLSDLPAWIQSCRRQGIQVLAATLAPLATCYWDHDLTRPTLFLLGNEGAGLQESTIQL 229

Query: 133 ADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           AD  + IPM   V+SLNV++   L+LYEA RQ++
Sbjct: 230 ADAQVRIPMAAGVESLNVAMTGGLLLYEALRQQR 263


>UniRef50_B0VI64 Putative tRNA/rRNA methyltransferase n=1 Tax=Candidatus Cloacamonas
           acidaminovorans RepID=B0VI64_9BACT
          Length = 269

 Score = 73.6 bits (179), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 43/143 (30%), Positives = 69/143 (48%), Gaps = 2/143 (1%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHE--VHAVWPGSRMRTMASAAAGSNSWVQVKTHR 77
           +TV  + +    NV ++ RTA+ +G+ +  V  + P      M   A G+   V  +   
Sbjct: 119 ITVICDNLRSVFNVGSLFRTAECLGIGKIIVCGITPTPEHSNMPKTAMGTEKLVAWQYFP 178

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
           +  +A+A    +G  I A    DNA    +  Y  P  I++G E  GI    L L D+ I
Sbjct: 179 STTEAIAFCHQEGFFIYALETIDNAKSVFQTVYQFPLAIVIGNEALGIESSILELCDEFI 238

Query: 138 IIPMIGMVQSLNVSVASALILYE 160
            +P +G   SLNV VA+ ++LY+
Sbjct: 239 TLPQLGWKNSLNVGVATGIVLYQ 261


>UniRef50_A4GI27 rRNA methyltransferase n=1 Tax=uncultured marine bacterium
           EB0_41B09 RepID=A4GI27_9BACT
          Length = 246

 Score = 73.6 bits (179), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 51/155 (32%), Positives = 79/155 (50%), Gaps = 11/155 (7%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEV-----HAVWPGSRMRTMASAAAGSNSWV 71
           +P L + ++ V  P N+ A  R ADA+GV  +     +AV   + +R +A   A S  +V
Sbjct: 96  KPLLFLILDGVVDPQNLGACFRVADAMGVDALICPKDNAVGLNATVRKVACGGAESVPFV 155

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNA-VDFREIDYTRPTCILMGQEKTGITQEAL 130
            V     +   + +LK   + +  T   DNA    ++ ++     ++MG E  G+ +   
Sbjct: 156 VVTN---LARTIRYLKNSNVFVYGT--DDNANKSLQKTNFKGSIALVMGSEGKGMRRLTN 210

Query: 131 ALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            L D    IPM+G V+SLNVSVAS + LYE  RQR
Sbjct: 211 ELCDDIFSIPMMGQVESLNVSVASGICLYEINRQR 245


>UniRef50_B1I4I6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Candidatus Desulforudis
           audaxviator MP104C RepID=B1I4I6_DESAP
          Length = 272

 Score = 73.6 bits (179), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 52/165 (31%), Positives = 81/165 (49%), Gaps = 7/165 (4%)

Query: 12  MLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR--TMASAAAGSNS 69
           +L  R   L V ++ +  P N+  IIRTADA  +  V  +     +    +  A+AG+  
Sbjct: 110 LLQGRGTPLVVVLDGLQDPGNLGTIIRTADACELQGVITLEGTVDLFHPKVVRASAGALF 169

Query: 70  WVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFR--EIDYTRPTCILMGQEKTGITQ 127
            +           +    G G+Q     ++D   D+   E D++RPT + MG E  G  +
Sbjct: 170 HLPAFGDLPAPAVLEFFTGAGVQ---KFVADPRGDYSLYECDFSRPTALFMGNEARGCGE 226

Query: 128 EALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYL 172
              A AD+ + IPM G  +SLNV VA++L +YEA RQR  + + L
Sbjct: 227 MLHAAADRVVAIPMPGQAESLNVGVAASLFIYEAVRQRLKSSLSL 271


>UniRef50_C4V3B4 TrmH family rRNA methyltransferase n=2 Tax=Selenomonas
           RepID=C4V3B4_9FIRM
          Length = 276

 Score = 73.6 bits (179), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 53/156 (33%), Positives = 79/156 (50%), Gaps = 9/156 (5%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEV-----HAVWPGSRMRTMASAAAGSNSWVQVK 74
           L + +++V  P NV  I+RTADA G   V      A   GS++     AA GS  ++   
Sbjct: 125 LYLALDRVQDPGNVGTILRTADAAGASGVILLRGCADVYGSKV---VRAAMGSLFYLPFV 181

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
           T     D V   K   +   A     + V     + +RP+ +++G E  G++ E L  A 
Sbjct: 182 TGVDEEDLVRFAKENVLCFYAAACDTDGVTHFAAELSRPSLVVLGNEANGVS-ERLLRAG 240

Query: 135 QDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGM 170
           Q + +PM G  +SLNV+ A+  ILYEA RQR+ AG+
Sbjct: 241 QHLYVPMCGRAESLNVAAAATAILYEAIRQRKYAGI 276


>UniRef50_B5JMU7 RNA methyltransferase, TrmH family n=1 Tax=Verrucomicrobiae
           bacterium DG1235 RepID=B5JMU7_9BACT
          Length = 273

 Score = 73.2 bits (178), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 43/150 (28%), Positives = 79/150 (52%), Gaps = 2/150 (1%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTH 76
            P   + +E + KP N+  I+R+ADA GV  V      + +    +  + +     + T 
Sbjct: 118 DPPFLLIVEAIEKPGNLGTILRSADAAGVDAVICCDSVTDLFNPNAVRSSTGVLFSMPTV 177

Query: 77  RTIGDAVAH-LKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
               D V   ++ +G++ +AT    + + + + D   P  I+MG E+ G++++ L+  D 
Sbjct: 178 TASSDEVIKWIRQKGIRTIATTPHTDIL-YTDTDLRGPLAIVMGSEQFGLSEKWLSACDT 236

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            ++IPM G   SLNV++A+ + L+EA RQR
Sbjct: 237 KVLIPMAGQADSLNVAMATLITLFEAVRQR 266


>UniRef50_C1F8Y2 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Acidobacterium
           capsulatum ATCC 51196 RepID=C1F8Y2_ACIC5
          Length = 270

 Score = 73.2 bits (178), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 47/154 (30%), Positives = 79/154 (51%), Gaps = 7/154 (4%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA----AGSNSWVQ 72
            P L + ++ V  P N+ A++R+AD  GV  V  + P  R   +++ A    AG+   ++
Sbjct: 96  HPHLLLALDGVEDPQNLGALLRSADGAGVDGV--LLPERRSAPLSAVAVKTSAGAAEHIR 153

Query: 73  VKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALAL 132
           +     +  A+  LK Q +  +        + +   D+T P+ +++G+E  G+       
Sbjct: 154 IARVVNLVRALEQLKEQNIWCVGLD-ERGTMSYDAYDWTTPSVVVLGREGEGLHDLVRKT 212

Query: 133 ADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            D  + IPM G V SLNVS A A++LYEA RQR+
Sbjct: 213 CDHLVRIPMAGGVSSLNVSAAGAVVLYEAARQRR 246


>UniRef50_C7H9L6 RNA methyltransferase, TrmH family, group 3 n=3 Tax=Ruminococcaceae
           RepID=C7H9L6_9FIRM
          Length = 267

 Score = 72.8 bits (177), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 48/158 (30%), Positives = 80/158 (50%), Gaps = 11/158 (6%)

Query: 15  RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP----GSRMRTMASAAAGSNSW 70
           + +P   V  + +  PHN+ A++R+A   G H +  V P     S   T+  ++AG+   
Sbjct: 111 KGEPPFLVLSDGIEDPHNLGAVMRSALLCGAHGI--VIPKRGGASVTPTVIKSSAGAAER 168

Query: 71  VQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEAL 130
           + V     IG+ +  LK QG+ +    +  + V  R+ + T P  +++G E +G++Q   
Sbjct: 169 LPVARVANIGETIRRLKDQGVFVYCADM--DGVPLRKNNLTGPIALVLGSEGSGVSQLVK 226

Query: 131 ALADQDIIIPMIGM---VQSLNVSVASALILYEAQRQR 165
            L D  + + M      V S NVSVA+ +ILYE Q QR
Sbjct: 227 KLCDGVVRLDMAAQGTGVDSFNVSVAAGIILYEIQSQR 264


>UniRef50_D0JB44 tRNA/rRNA methyltransferase n=2 Tax=Blattabacterium
           RepID=D0JB44_BLASB
          Length = 253

 Score = 72.8 bits (177), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 44/152 (28%), Positives = 80/152 (52%), Gaps = 7/152 (4%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKT---- 75
           L V ++++    N  +IIRT+  VG   +  + P      + S +  ++S    K     
Sbjct: 99  LLVILDRITDVRNFGSIIRTSACVGADAI--IIPKKYTAMIGSDSIKTSSGALFKVPICQ 156

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
            + I + +  L   G++I++     N + +  ID++ PT +++G E+ GI+ + L ++ +
Sbjct: 157 EKNIKNTIEFLMNSGLKIVSATEKSN-IYWYNIDFSGPTALILGNEEKGISPKYLEISCE 215

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
              IP I  + SLNVSVA  +ILYE  RQR++
Sbjct: 216 KAKIPAIKGISSLNVSVACGVILYEVFRQRKS 247


>UniRef50_B0K3L2 tRNA/rRNA methyltransferase (SpoU) n=11 Tax=Thermoanaerobacterales
           RepID=B0K3L2_THEPX
          Length = 254

 Score = 72.8 bits (177), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 43/150 (28%), Positives = 72/150 (48%), Gaps = 3/150 (2%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKT 75
           +   + +  + +  P N+  IIRTADA G   +  +     +       A   S   +  
Sbjct: 103 KDKGIYIIADNIQDPGNLGTIIRTADAFGASAIFTINNCVDVFNPKVLRASMGSIFHIPV 162

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
             T    +  LK +G+++ ATHL    +   E + +     ++G E  G++   + L D 
Sbjct: 163 IVTASQILLKLKQRGIKVFATHLKARKL-VHECNISDKVAFVLGNEAKGVS--VVDLVDD 219

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            + IPM G  +SLNVS+A+ + LYE+QRQR
Sbjct: 220 FVKIPMTGEAESLNVSIAAGIFLYESQRQR 249


>UniRef50_Q0BY95 RNA methyltransferase, TrmH family n=1 Tax=Hyphomonas neptunium
           ATCC 15444 RepID=Q0BY95_HYPNA
          Length = 271

 Score = 72.4 bits (176), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 52/150 (34%), Positives = 73/150 (48%), Gaps = 2/150 (1%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTI 79
           L + + +V  P N+  I+RTAD  GV  V  +       +  +  A   S   V    T 
Sbjct: 123 LYIALYEVRDPGNLGTILRTADCAGVSGVILIGTCCDPYSFEAVRASMGSVFDVPFAHTD 182

Query: 80  GDAVAHL-KGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
            DA     KG+GM + A  + +  V     D+T  + ILMG E+ G+     A  D   +
Sbjct: 183 FDAFNTWRKGEGMSLTAASV-NGTVRHDGADFTGGSIILMGNEQAGLPDWVEAACDTLSL 241

Query: 139 IPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           IPM G   SLN++ ASAL++YEA RQR  A
Sbjct: 242 IPMRGGADSLNLAQASALMIYEAWRQRGYA 271


>UniRef50_C1F3I9 RNA methyltransferase, TrmH family protein n=1 Tax=Acidobacterium
           capsulatum ATCC 51196 RepID=C1F3I9_ACIC5
          Length = 283

 Score = 72.4 bits (176), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 49/151 (32%), Positives = 79/151 (52%), Gaps = 6/151 (3%)

Query: 18  PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM---RTMASAAAGSNSWVQVK 74
           P L +    +  P N+  +IR+A+A G   +  + PG+       +  A+AGS   + V 
Sbjct: 129 PALLLVTASLQDPGNLGTLIRSAEAFGASGILTL-PGTVNLWNAKVVRASAGSVFRMPV- 186

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
             R   + +A L  QG+ + AT  +D  +   +   T+P  +L+G E  G+T   L  AD
Sbjct: 187 VARCEEEVLARLAAQGVTLFATT-ADGDLPATQAALTQPCALLIGNEGAGLTPHLLQAAD 245

Query: 135 QDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             + IP  G V+SLN ++A +++LYEA RQR
Sbjct: 246 ARLAIPTPGPVESLNAAIAGSILLYEASRQR 276


>UniRef50_B5EQA2 RNA methyltransferase, TrmH family, group 3 n=3
           Tax=Acidithiobacillus RepID=B5EQA2_ACIF5
          Length = 255

 Score = 72.4 bits (176), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 48/152 (31%), Positives = 79/152 (51%), Gaps = 7/152 (4%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM----RTMASAAAGSNSWVQVKT 75
             + ++ V  PHN+ A +R+A+A GV  V  + P         T+  A+AGS S V V T
Sbjct: 94  FLLVLDGVLDPHNLGACLRSAEAAGVDAV--ILPRDNACPVNATVRKASAGSASRVPVCT 151

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
              +   ++ L+  G  ++     + +     +D   P  ++MG E+ G+ +      D 
Sbjct: 152 VTNLSRTLSSLQEAGFWLVGMA-GEGSRSLYALDLDMPLVMVMGGEEKGLRRLTREHCDY 210

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
              IPM+G ++SLNVSVA+ + L+EA RQR+N
Sbjct: 211 LAHIPMMGAIESLNVSVATGICLFEAARQRRN 242


>UniRef50_B8HJN1 RNA methyltransferase, TrmH family, group 3 n=6 Tax=Bacteria
           RepID=B8HJN1_CYAP4
          Length = 387

 Score = 72.4 bits (176), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 49/150 (32%), Positives = 76/150 (50%), Gaps = 7/150 (4%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAAGSNSWVQVKTHR 77
           +  + +  PHN+ AIIRTA+A+G   +  V P  R      T+A  AAG+     V    
Sbjct: 222 LAADGITDPHNLGAIIRTAEALGAQGL--VVPQRRAVGITSTVAKVAAGALEHFAVARVV 279

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            +  A+  LK  G  I     +  A     ++++ P  +++G E TG++  A    DQ +
Sbjct: 280 NLNQALEQLKAAGFWIYGM-AATAAKPIYSVEFSGPVVLVVGAEGTGLSLLAQRYCDQLV 338

Query: 138 IIPMIGMVQSLNVSVASALILYEAQRQRQN 167
            IP++G   SLN SVA+ + LYE  RQR +
Sbjct: 339 SIPLLGKTPSLNASVATGMALYEIFRQRSS 368


>UniRef50_Q11C30 tRNA/rRNA methyltransferase (SpoU) n=21 Tax=Alphaproteobacteria
           RepID=Q11C30_MESSB
          Length = 286

 Score = 72.4 bits (176), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 51/150 (34%), Positives = 78/150 (52%), Gaps = 9/150 (6%)

Query: 19  DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRT 78
           DL V +++V  P N+  IIRT DAVG   V  V   +   ++ +  A   S   V   R 
Sbjct: 130 DLWVALDRVRDPGNLGTIIRTVDAVGARGVILVGECTDPFSVETVRATMGSVFSVPLARA 189

Query: 79  IGDAVAHLKGQ----GMQILATHLSDNAVDFREIDYTR-PTCILMGQEKTGITQEALALA 133
             D  A L  +    G+ +  THL   +VD+R +DY+  P  +LMG E+ G+  +     
Sbjct: 190 --DEAAFLAWREHFAGLMV-GTHLK-GSVDYRNVDYSGGPVLLLMGNEQQGLPDKLAEAC 245

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           D+ + IP  G   SLN++VA+ ++LYE +R
Sbjct: 246 DRLVRIPQAGRADSLNLAVATGVMLYEIRR 275


>UniRef50_Q7VQP0 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=2
           Tax=Candidatus Blochmannia RepID=RLMB_BLOFL
          Length = 254

 Score = 72.4 bits (176), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 50/153 (32%), Positives = 78/153 (50%), Gaps = 11/153 (7%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR----TMASAAAGSNSWVQVKT 75
           L + ++ +  PHN+ A IR+ADA GVH +  + P  R      T+   A+GS+  V    
Sbjct: 98  LLLVLDGITDPHNLGACIRSADAAGVHMI--IVPRDRSANVNATVRKVASGSSDRVPFVR 155

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDF--REIDYTRPTCILMGQEKTGITQEALALA 133
              +   +  LK   + I+ + L  N + F  R ID   P  ++MG E +GI +      
Sbjct: 156 VTNLSRTLKLLKKYNIYIVGSVLRSNQILFNTRLID---PIALVMGSESSGIRRLTRENC 212

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           D+ + IP +    SLNVSVA+ + L+E  RQR+
Sbjct: 213 DKLVHIPTLQSTVSLNVSVATGIFLFETVRQRK 245


>UniRef50_D1AKE9 tRNA/rRNA methyltransferase (SpoU) n=17 Tax=Fusobacteriaceae
           RepID=D1AKE9_SEBTE
          Length = 256

 Score = 72.4 bits (176), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 46/168 (27%), Positives = 77/168 (45%), Gaps = 12/168 (7%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHA------VWPGSRMRT 59
           Y+++   +     D+ V ++ V  P N+  IIRT +A G   +        V+    +R 
Sbjct: 94  YSKLLTSIEEIDGDV-VILDDVQDPGNIGTIIRTMEASGFKNLILTKGSVDVYNPKTVRA 152

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
                  SN   +     T       LK    Q+++T L  N++D+R+++       + G
Sbjct: 153 TMGGIFKSNIIYETPERIT-----EFLKDNNYQVISTLLDKNSIDYRDVELKEKNAYIFG 207

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
            E  GI+   +   D   IIP+ G V SLNVSVAS + LY+ + + +N
Sbjct: 208 NEGHGISDIFIESTDIKAIIPIYGDVDSLNVSVASGIFLYKMREKIEN 255


>UniRef50_Q0AUG1 Conserved hypothetical tRNA/rRNA methyltransferase yacO n=1
           Tax=Syntrophomonas wolfei subsp. wolfei str. Goettingen
           RepID=Q0AUG1_SYNWW
          Length = 248

 Score = 72.4 bits (176), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 47/160 (29%), Positives = 77/160 (48%), Gaps = 13/160 (8%)

Query: 15  RRQPDLTVCMEQVHKPHNVSAIIRTADAVGV-------HEVHAVWPGSRMRTMASAAAGS 67
           + +P   + ++ +  P N+ AIIRTA+  GV       H+   V P     T++  +AG+
Sbjct: 91  KEKPPFLLLLDGIEDPQNLGAIIRTAECAGVDGIIIPSHKSAEVNP-----TVSRVSAGA 145

Query: 68  NSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQ 127
              + +     + + + +LK +G  +L          F       PT +++G E  GI +
Sbjct: 146 VEHMAIIRENNLVNTIKYLKQEGFWVLGADAKARQSYF-NTSIPSPTALVIGGEGQGIRR 204

Query: 128 EALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
                 D  + IPM G + SLN SVA+AL++YE  RQR N
Sbjct: 205 LVRENCDILVRIPMFGQLNSLNASVAAALLIYEVLRQRLN 244


>UniRef50_Q1IND6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Candidatus Koribacter
           versatilis Ellin345 RepID=Q1IND6_ACIBL
          Length = 285

 Score = 72.0 bits (175), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 51/164 (31%), Positives = 84/164 (51%), Gaps = 12/164 (7%)

Query: 10  CEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEV------HAVWPGSRMRTMASA 63
            E L R +  + + +  V  P N+  I+R+A+A G   V       + W    +R  +S 
Sbjct: 127 LEDLLRAENPMLLGVAGVQDPGNLGTILRSAEAFGATGVLIGDKTASPWNPKVIRG-SSG 185

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           +      V+V+       A+  L+ +G+QILAT  S       E+D+T PT +L+G E  
Sbjct: 186 SVFRLPVVKVEWPA----ALEQLRAKGVQILATS-SHKGEPLPEVDFTGPTIVLIGGEGA 240

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           G+ ++ LA  D  + IP    V+SLN  +A+++++YEA RQR  
Sbjct: 241 GVPRDVLASVDGTLAIPHSPKVESLNAGIAASIVMYEAARQRNT 284


>UniRef50_D2RLA3 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Acidaminococcus
           RepID=D2RLA3_ACIFE
          Length = 260

 Score = 72.0 bits (175), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 50/170 (29%), Positives = 87/170 (51%), Gaps = 9/170 (5%)

Query: 2   NPTRYARICEM----LARRQPD--LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS 55
           +P   A + E+    LA   P+  + + ++++  P N+  +IRTADA+G   V  +   +
Sbjct: 88  DPQSVAALVELRREELAAFAPERGMVLVLDRIRDPGNLGTLIRTADALGAAGVVLLENTA 147

Query: 56  RMRT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
            +    +  +  GS   + V T    G+     +  G  + AT L + A D   + +   
Sbjct: 148 DLYNPKVVRSTMGSLFHLPVFTGVKTGELEEWCRQHGYALWATAL-EGAEDMTRLTWPEK 206

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           T +++G E  G++ E LA ADQ + IPM G  +SLNV+VA  ++++EA R
Sbjct: 207 TALVLGSEAEGVSPEILAAADQKVKIPMAGHAESLNVAVAGGIVMFEAAR 256


>UniRef50_Q31FJ2 RNA methyltransferase TrmH, group 3 n=1 Tax=Thiomicrospira
           crunogena XCL-2 RepID=Q31FJ2_THICR
          Length = 244

 Score = 71.6 bits (174), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 56/171 (32%), Positives = 88/171 (51%), Gaps = 14/171 (8%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEV-----HAVWPGS 55
           +N T    + E  A   P L + +++V  PHN+ AI+RTADA GV  V     ++V   +
Sbjct: 79  LNETDLKALLE--AESNP-LFLFLDEVQDPHNLGAILRTADATGVTAVVIPKHNSVGVNA 135

Query: 56  RMRTMASAAAGSNSWVQVKTH-RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
            +R +A  AA +   V V    RTI +    L+  G+ +       N   + ++D+    
Sbjct: 136 TVRKVACGAAETVKVVVVSNLVRTIKE----LQQAGLWVTGLAGETNTTLY-QLDFKGAV 190

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            ++MG E +G+ +      D    IPM G ++SLNVSVA+ ++LYE  RQR
Sbjct: 191 GLVMGAEGSGLRKLTRETCDHLAAIPMAGSIESLNVSVATGVVLYEVYRQR 241


>UniRef50_C0GIN0 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Dethiobacter
           alkaliphilus AHT 1 RepID=C0GIN0_9FIRM
          Length = 245

 Score = 71.6 bits (174), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 51/171 (29%), Positives = 82/171 (47%), Gaps = 9/171 (5%)

Query: 3   PTRYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           P RY    ++LA+   +P   V ++ +  PHN+ A+IRTA A G   +  + P  R   M
Sbjct: 77  PFRYTPFADILAKAGDKPPFLVLLDHIQDPHNLGALIRTAYAAGCDGI--IIPERRAAQM 134

Query: 61  A----SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
                  AAG+  ++ V     +   +   K  G+ +    +   +V +   DY   T +
Sbjct: 135 TPAAVRTAAGAAEYLPVAKVVNLARCLDECKDAGLWVYGADMDGESV-YTTGDYQGGTVL 193

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           ++G E  G+ +      D  + +PM G V SLN SVA AL++YE  RQR+ 
Sbjct: 194 VIGSEGEGLGRLVKEKCDHLVQLPMQGKVASLNASVAGALLMYEVYRQREG 244


>UniRef50_C4ZGM4 RNA methyltransferase, TrmH family, group 3 n=8 Tax=Clostridiales
           RepID=C4ZGM4_EUBR3
          Length = 263

 Score = 71.6 bits (174), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 48/168 (28%), Positives = 79/168 (47%), Gaps = 14/168 (8%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVH-------EVHAVWPGSRMRTMA 61
           I E+    + +L V +E +  P N+  ++RT +  GV         V    P +   TM 
Sbjct: 102 IDELFKGDKTELLV-LESIQDPGNLGTMVRTGEGAGVSGIIMNRTTVDIFNPKTVRSTM- 159

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
               GS   V       + + + + K +G+ + A HL      +   DYT     ++G E
Sbjct: 160 ----GSLYRVPFYITDDLPETIEYAKSKGVSLYAAHLK-GKCSYDRPDYTGACGFMIGNE 214

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
             G++ E   +AD  I IPM G V+SLN ++++ L++YE  RQR+  G
Sbjct: 215 GNGLSDEIADMADTYIRIPMEGAVESLNAAISATLLMYECNRQRRLLG 262


>UniRef50_Q606P1 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Methylococcus
           capsulatus RepID=Q606P1_METCA
          Length = 250

 Score = 71.6 bits (174), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 46/148 (31%), Positives = 73/148 (49%), Gaps = 3/148 (2%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS--RMRTMASAAAGSNSWVQVKTHR 77
           L + ++ V  PHN+ A +RT DA GV  +      S     T+A  A+G+   V V    
Sbjct: 99  LYLVLDHVQDPHNLGACLRTCDAAGVKGLVVTKDQSVGLTPTVAKVASGAAETVPVYRVT 158

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            +   +   K +G  ++     +      E+D   P  ++MG E  G+ +      D  +
Sbjct: 159 NLARCLDRFKQRGYWVVGAA-GEAERTLYELDLRLPLVVVMGAEGVGLRRLTRERCDFLL 217

Query: 138 IIPMIGMVQSLNVSVASALILYEAQRQR 165
            IPM+G V+SLN+SVA+ ++LYE  RQR
Sbjct: 218 RIPMVGGVESLNLSVATGIVLYEVMRQR 245


>UniRef50_B1X411 tRNA/rRNA methyltransferase (SpoU):RNA methyltransferase TrmH n=1
           Tax=Paulinella chromatophora RepID=B1X411_PAUCH
          Length = 526

 Score = 71.6 bits (174), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 50/149 (33%), Positives = 78/149 (52%), Gaps = 7/149 (4%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAAGSNSWVQVKT 75
           L + +E +  PHN+ AI+R+A+A+G H +  + P  R      ++A  AAG+   + V  
Sbjct: 285 LLMAVEGLTDPHNLGAIVRSAEALGAHGL--ILPQRRNAGLTGSVAKVAAGALEHLPVAR 342

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
              +  ++  LK +G +I+    ++  V   E D   P  I+ G E  G++       DQ
Sbjct: 343 VVNLNRSLDILKDKGYRIVGL-ATEGDVSLTEADLNGPLVIVTGSEGNGLSLLTRRYCDQ 401

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            I IP+ G   SLN SVASAL+LYE  R+
Sbjct: 402 LIRIPLRGATPSLNASVASALMLYEVARR 430


>UniRef50_B8I1W5 RNA methyltransferase, TrmH family, group 3 n=5 Tax=Clostridium
           RepID=B8I1W5_CLOCE
          Length = 269

 Score = 71.6 bits (174), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 50/151 (33%), Positives = 76/151 (50%), Gaps = 13/151 (8%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEV-------HAVWPGSRMRTMASAAAGSNSWVQVK 74
           V ++ +  P N   IIRTADA G+  V           P     TM     GS   + + 
Sbjct: 119 VILDCLQDPGNAGTIIRTADAAGISAVLMSKGCVDLYSPKVLRSTM-----GSVFHIPIF 173

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
               I + +  LK    +++A+HLS     F+E D T  + I++G E  GI+ E   +AD
Sbjct: 174 EGLNITEIIRVLKQNDYKVIASHLSGKNNYFQE-DLTGRSAIIVGNEANGISDETAYMAD 232

Query: 135 QDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             + IPM G  +SLN SVA+++++YE  RQ+
Sbjct: 233 SLVKIPMPGKAESLNASVAASVMIYEIVRQK 263


>UniRef50_D1CFS4 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Thermobaculum terrenum
           ATCC BAA-798 RepID=D1CFS4_THET1
          Length = 266

 Score = 71.2 bits (173), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 45/155 (29%), Positives = 78/155 (50%)

Query: 11  EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSW 70
           E +  R+    + ++ V  P N+ +I+RTADAVGV  V  +          S  AG+ + 
Sbjct: 109 ESIDPREGLCLLALKAVQDPGNIGSILRTADAVGVRYVILLGDSVDPYDPNSVRAGAGAT 168

Query: 71  VQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEAL 130
             VK  +T  + +   K      +   +    +++  ++Y  P  +LMG E+ G+     
Sbjct: 169 FTVKLIKTSFERLLDWKNIHQIPVIGAVGGAPLNYSRVNYPYPCILLMGSERQGLDLREQ 228

Query: 131 ALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +  D  + +PM+G V SLN++VA+++ILYE   QR
Sbjct: 229 SSCDMLVSVPMVGKVDSLNLAVATSVILYEIFDQR 263


>UniRef50_B2S257 Possible rRNA methylase n=3 Tax=Treponema RepID=B2S257_TREPS
          Length = 292

 Score = 71.2 bits (173), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 52/172 (30%), Positives = 82/172 (47%), Gaps = 6/172 (3%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEV---HAVWPGSRMRTMASAAA 65
           +   LA     L + ++ +  PHNV AI+R+AD   V  V   H    G    T+   +A
Sbjct: 121 LLHALATHTHALVLVLDAITDPHNVGAIVRSADQFSVDAVLLPHHHGAGG-TETITRVSA 179

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G+ +WV +   R +      LK  G  +    ++  A+  R   +   T +++G E  G+
Sbjct: 180 GAVAWVPLVRVRNLVRTAGILKRSGFWLYGADVAGEAIGART--FPPKTALVLGNEGHGV 237

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSM 177
           +       D  I IP  G V SLNVSVA+ ++LYE +R +Q+     R+N M
Sbjct: 238 SPLLRTHCDALISIPTQGNVDSLNVSVAAGILLYEIRRSQQSPYSVQRQNEM 289


>UniRef50_Q7MBB6 tRNA/rRNA methyltransferase n=1 Tax=Gloeobacter violaceus
           RepID=Q7MBB6_GLOVI
          Length = 338

 Score = 70.9 bits (172), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 48/162 (29%), Positives = 79/162 (48%), Gaps = 8/162 (4%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAA 64
           I  ++ R  P L +  + +  PHN+ A+IR+A+A G   +  + P  R      T+A  A
Sbjct: 174 IASLVERPDPVL-LAADGIEDPHNLGALIRSAEAFGFQGI--ILPQRRAVGVTATVAKVA 230

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTG 124
           AG+   + +     +  A+  LK  G Q++ T    +   + E+    P  +++G E  G
Sbjct: 231 AGAVEHLPIARVTNLNQAIERLKEAGYQVVGTQEKASQALY-ELKLDGPLVVVVGSEGKG 289

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           I+       D  + IP+ G   SLN SVA  ++LYE  RQR+
Sbjct: 290 ISLLTQRHCDHMVSIPLAGKTTSLNASVAGGIMLYEVMRQRR 331


>UniRef50_A6KZH0 tRNA/rRNA methyltransferase n=10 Tax=Bacteroidales
           RepID=A6KZH0_BACV8
          Length = 178

 Score = 70.9 bits (172), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 48/148 (32%), Positives = 72/148 (48%), Gaps = 10/148 (6%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVH-----AVWPGSRMRTMASAAAGSNSWVQVK 74
           L V +++V   HN+ ++ RT+DA  V  ++     A  P   M   A  A  S  W   +
Sbjct: 25  LAVVLDEVRSLHNIGSVFRTSDAFLVDCIYLCGITATPPHPEMHKTALGAEYSVEW---R 81

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNA--VDFREIDYTRPTCILMGQEKTGITQEALAL 132
             +   DAV  L  QG  +LA    + +  +D  E+D  +   I+MG E  G+ QE +  
Sbjct: 82  YKKNTLDAVQELHDQGFTVLAIEQVEGSTLLDKLELDADKKYAIVMGNEVKGVQQEVVNA 141

Query: 133 ADQDIIIPMIGMVQSLNVSVASALILYE 160
            D  + IP  G   SLNVSV + +IL+E
Sbjct: 142 CDGCVEIPQYGTKHSLNVSVTTGIILWE 169


>UniRef50_A6P2D0 Putative uncharacterized protein n=1 Tax=Bacteroides capillosus
           ATCC 29799 RepID=A6P2D0_9BACE
          Length = 252

 Score = 70.9 bits (172), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 48/147 (32%), Positives = 74/147 (50%), Gaps = 14/147 (9%)

Query: 24  MEQVHKPHNVSAIIRTADAVGVHEVHAV------WPGSRMRTMASAAAGSNSW-VQVKTH 76
           ++ V  P N+  I RTADA G   +  V      W    +R    A     +W   ++T 
Sbjct: 113 LDGVQDPGNLGTIWRTADAFGADGLLLVNGCADPWSPKTIRATMGACFRLPAWETDLETV 172

Query: 77  RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQD 136
           R      A L G  + + AT L ++ VD R++D  R   +++G E  GI+ EALAL  + 
Sbjct: 173 R------ALLDGADIPLYATALREDTVDVRDVDLKR-AAVVIGSEGRGISDEALALCRRT 225

Query: 137 IIIPMIGMVQSLNVSVASALILYEAQR 163
           I IPM    +SLN ++A+ ++L+E  R
Sbjct: 226 IKIPMRARCESLNAAMAAGVVLWEMCR 252


>UniRef50_Q7NAH8 SpoU n=2 Tax=Mycoplasma RepID=Q7NAH8_MYCGA
          Length = 260

 Score = 70.9 bits (172), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 44/163 (26%), Positives = 84/163 (51%), Gaps = 5/163 (3%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG--SRMRTMASA 63
           + + CE +   Q  + V ++Q+H P N   I+R+  A  V  V        S   T+   
Sbjct: 97  FNQFCEKIKNEQQGIVVVLDQIHDPGNFGGILRSCLAANVLGVIFKKDNQVSINNTVIKT 156

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQ-GMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
           + G+  ++ +     +  A+  L+ + G     ++LSD A D+  +DY   + +++G E+
Sbjct: 157 SLGACFYLNLIEVANLSYAIKDLQEKYGFWSYVSNLSDQAQDYN-VDYANKSILIVGNEQ 215

Query: 123 TGITQEALALADQDIIIPMI-GMVQSLNVSVASALILYEAQRQ 164
            G++ + +  AD  I IPM    +QSLNVSVA+ ++L+  +++
Sbjct: 216 KGVSSQLIKNADYQIKIPMYTDKIQSLNVSVATGIMLFNMKQK 258


>UniRef50_C1ZH70 rRNA methylase, putative, group 3 n=1 Tax=Planctomyces limnophilus
           DSM 3776 RepID=C1ZH70_PLALI
          Length = 271

 Score = 70.9 bits (172), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 49/162 (30%), Positives = 87/162 (53%), Gaps = 5/162 (3%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG-SRMRTMAS-A 63
           YA    +   + P L V ++ +    N+ AIIR A+A+G   +     G S + + A+ +
Sbjct: 108 YADFEGLFQAQLPALLVILDGIQDSFNLGAIIRCAEALGAGGIVLPEKGQSGVNSQAARS 167

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILA-THLSDNAVDFREIDYTRPTCILMGQEK 122
           +AG+ +++ +     +  A+  LK +GM+ILA T  S+ ++    +    P C+++G E 
Sbjct: 168 SAGAVNFLPIYRVPALDRAIDQLKSRGMKILAATEKSEQSL--WNVVIPAPLCLIIGNEG 225

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            G++   L+  D  + IPM G   SLN +VA+ ++L E QRQ
Sbjct: 226 KGVSSALLSACDIQVRIPMAGQTSSLNAAVAAGILLAEIQRQ 267


>UniRef50_C0X8M7 RNA methyltransferase n=36 Tax=Enterococcus RepID=C0X8M7_ENTFA
          Length = 258

 Score = 70.9 bits (172), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 41/150 (27%), Positives = 80/150 (53%), Gaps = 11/150 (7%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEV------HAVWPGSRMRTMASAAAGSNSWVQVKT 75
           + ++ +  P NV  +IRTADA G+  V        ++    +R+M     GS+  + V  
Sbjct: 114 LLLDNIQDPGNVGTMIRTADAAGLAGVILGKGTADIYNTKVLRSMQ----GSHYHLPV-L 168

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
            R + + V   K QG+ +  T L++ A+ + E +      +++G E +G++ E LA   +
Sbjct: 169 QRELTEVVQAFKKQGLPVFGTELNEAAIAYYEQEAVENYALILGNEGSGVSPELLAETTK 228

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           ++ IPM G  +SLNV++A+ ++++  Q  +
Sbjct: 229 NLYIPMKGQAESLNVAIAAGVLMFYFQNNQ 258


>UniRef50_A9AZL1 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Herpetosiphon
           aurantiacus ATCC 23779 RepID=A9AZL1_HERA2
          Length = 266

 Score = 70.9 bits (172), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 46/146 (31%), Positives = 74/146 (50%), Gaps = 2/146 (1%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGD 81
           V +  V  P N+ AI+RT DAVG   +  +   +     A+  A   S   ++  RT  D
Sbjct: 120 VALNGVGNPGNLGAIMRTCDAVGCEGLILIGDTTDPYHPAAIRASMGSLFALRMVRTTFD 179

Query: 82  AVAHLK-GQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIP 140
             A  K   G  ++ T   D   +++ I Y  P  +LMG E+ G++    ++ D  + IP
Sbjct: 180 EFAAWKQTNGYHVIGTT-PDVEQEYQTISYPSPAILLMGSERLGLSVGEQSVCDTLVRIP 238

Query: 141 MIGMVQSLNVSVASALILYEAQRQRQ 166
           M G   SLN+ VA++++LYE  RQ++
Sbjct: 239 MAGTCDSLNLGVATSIVLYEMFRQQR 264


>UniRef50_D2R809 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Pirellula staleyi DSM
           6068 RepID=D2R809_9PLAN
          Length = 177

 Score = 70.5 bits (171), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 40/133 (30%), Positives = 74/133 (55%), Gaps = 3/133 (2%)

Query: 32  NVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGM 91
           N+S I RTA   G+ ++ A   G   +T+A   A     ++++ HRT+   +  L+ +G 
Sbjct: 44  NLSNIARTASCCGLTKIVACGQGKLDKTVARDGADE---LEIEVHRTLLPVLKELRKEGW 100

Query: 92  QILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVS 151
            + A   + ++V+  E  + R   +++G E+ G++ E L+L +  + IP+ G+  S NV+
Sbjct: 101 FLAALEQTTDSVNMHEYQFPRKVALVIGNERHGLSDEELSLMNVCLEIPVWGLPHSYNVA 160

Query: 152 VASALILYEAQRQ 164
            A+A+ LYE  RQ
Sbjct: 161 NATAMALYEYCRQ 173


>UniRef50_A4XJ85 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Clostridia
           RepID=A4XJ85_CALS8
          Length = 253

 Score = 70.5 bits (171), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 47/164 (28%), Positives = 80/164 (48%), Gaps = 5/164 (3%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEV--HAVWPGSRMRTMASAAAG 66
           + E   + +    V ++++  PHN  +IIR+A   G H +   A        T+  A+AG
Sbjct: 84  LLEAANKGEKPFLVLLDEITDPHNFGSIIRSAHLCGAHGIITEARNSCPITPTVEKASAG 143

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDF-REIDYTRPTCILMGQEKTGI 125
           +   ++V     +   +  LK +G+ + A    +NA  F  + D+  P CI++G E  GI
Sbjct: 144 AIEHIKVARVVNLRRTIDSLKEKGVWVYAA--DNNAEKFVYDCDFKIPICIIIGSEGKGI 201

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
           ++     AD  + IP  G + S N SVA+ +I +E  +QR   G
Sbjct: 202 SRLVKEGADFLVKIPQKGKINSYNASVAAGIIFFEVLKQRMQEG 245


>UniRef50_B4WGZ3 RNA methyltransferase, TrmH family n=5 Tax=Bacteria
           RepID=B4WGZ3_9SYNE
          Length = 213

 Score = 70.1 bits (170), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 54/189 (28%), Positives = 86/189 (45%), Gaps = 18/189 (9%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM----------RTMASAAA 65
           R  +L   +E  +   N+  IIR  +A+GV + + V P   +          R ++  + 
Sbjct: 22  RCKNLIAVIENPNDIKNIGTIIRNVNALGVEKAYIVDPKKALPDDWQEMREKRALSKTSV 81

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILAT--HLS--DNAVDFREIDYTRPT--CILMG 119
            +  W  VK   +    + HL+      + T  HL    NAV   E DYT  T   +  G
Sbjct: 82  SAIKWSFVKRFDSTAACIDHLEQNRFVSIVTSPHLKGRKNAV-LDEADYTIYTKLAVWFG 140

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN-AGMYLRENSML 178
            E  GI+  A+  +D  + IPM GM++SLN+   S ++LYE  +QR+     Y   N+  
Sbjct: 141 NESMGISDLAVEHSDLCVSIPMFGMIESLNLGTTSGIVLYEITKQRREYQHQYRWRNNRG 200

Query: 179 PEAEQQRLL 187
           P+   +R L
Sbjct: 201 PKLNNERSL 209


>UniRef50_D1J7J9 tRNA/rRNA methyltransferase n=2 Tax=Mycoplasma RepID=D1J7J9_MYCHP
          Length = 230

 Score = 70.1 bits (170), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 43/158 (27%), Positives = 78/158 (49%), Gaps = 7/158 (4%)

Query: 13  LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAAGSN 68
           + +   D  + ++ +  P N  AIIR+A+  G    H + P  R      ++   ++G  
Sbjct: 75  IFKDGSDKVLILDHIQDPQNFGAIIRSANVFGFK--HIIIPKDRACDVTPSVLKTSSGGF 132

Query: 69  SWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQE 128
             V+V    ++ DA+  LK +G  I A+ L+  A    +  +     I++G E +G+++ 
Sbjct: 133 KNVKVIKVNSLFDAIEELKNKGFWIYASALNQQAKKLNDAKFNEKIAIIVGNEGSGVSKT 192

Query: 129 ALALADQDIIIPMIG-MVQSLNVSVASALILYEAQRQR 165
            L  +D+ I I      VQSLNVSVA+ ++LY    ++
Sbjct: 193 LLKHSDEIIYIEQDKESVQSLNVSVATGILLYTVFNKK 230


>UniRef50_A2U3D3 SpoU rRNA methylase n=2 Tax=Flavobacteriaceae RepID=A2U3D3_9FLAO
          Length = 248

 Score = 70.1 bits (170), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 47/157 (29%), Positives = 81/157 (51%), Gaps = 8/157 (5%)

Query: 14  ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS---RMRTMASAAAGSNSW 70
           A + P   + ++Q+    N  AIIRTA+  GV+ +     GS      T+ ++A  +   
Sbjct: 93  AEKVP-FFLILDQLSDVRNFGAIIRTAECTGVNGIIIQKNGSAPVNAETIKTSAGAAFKM 151

Query: 71  VQVKTHRTIGDAVAHLKGQGMQ-ILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEA 129
              K    I DA+  L+   ++ + AT  +D+++   ++++ +P  I+MG E  G+    
Sbjct: 152 PICKVDH-IKDALFILQASNIKTVAATEKTDSSI--YDVNFNQPIAIIMGSEHRGVNPSV 208

Query: 130 LALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           L + D    +P+ G ++SLNVSVA  + LYE  RQR 
Sbjct: 209 LKMVDYKAKLPLSGNIESLNVSVACGVFLYETVRQRS 245


>UniRef50_B5YIM1 RNA methyltransferase, TrmH family n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YIM1_THEYD
          Length = 261

 Score = 70.1 bits (170), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 46/155 (29%), Positives = 74/155 (47%), Gaps = 12/155 (7%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAV------WPGSRMRTMASAAAGSNSW 70
            P   V  +++  P N+  IIR A+A G   V         +    +R    A+AGS  +
Sbjct: 108 NPTFIVIADRIQDPGNIGTIIRAAEAFGAEAVLVTHGTCNPFSNKALR----ASAGSIFF 163

Query: 71  VQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEAL 130
           + V    T+ +    +   G+ ++ T L      F  +D+T+P  I+ G E  G++Q+  
Sbjct: 164 LPV-IKVTVKEIEEFVSKYGLNLVITDLKATISSFN-MDFTKPLAIVFGNESKGVSQDLR 221

Query: 131 ALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           A+      IP  G  +SLNV++A+  ILYE  RQR
Sbjct: 222 AIKHTSCKIPHKGKAESLNVAMAATAILYEILRQR 256


>UniRef50_D1R5P1 Putative uncharacterized protein n=1 Tax=Parachlamydia
           acanthamoebae str. Hall's coccus RepID=D1R5P1_9CHLA
          Length = 277

 Score = 70.1 bits (170), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 47/148 (31%), Positives = 76/148 (51%), Gaps = 6/148 (4%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIG- 80
           +  E + KP N+  I+R +DAVG+  +      + +       A   +   V    + G 
Sbjct: 130 IVAEAIEKPGNLGTILRCSDAVGLDALIVCDACTDIHNPNVVRASVGTLFTVPVIESQGA 189

Query: 81  DAVAHLKGQGMQILAT--HLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           + +  LK +G+ ILA   H      D   ID T P  I +G E+ G++ + +  AD  + 
Sbjct: 190 ETLQWLKQKGISILAATPHAKQELAD---IDLTGPLAIAVGTEQLGLSPQWMEQADIQVR 246

Query: 139 IPMIGMVQSLNVSVASALILYEAQRQRQ 166
           IPM G+  SLNV++A+ ++LYEA RQR+
Sbjct: 247 IPMYGIADSLNVAMATTILLYEALRQRK 274


>UniRef50_Q88DE7 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=285
           Tax=Proteobacteria RepID=RLMB_PSEPK
          Length = 248

 Score = 70.1 bits (170), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 47/153 (30%), Positives = 77/153 (50%), Gaps = 7/153 (4%)

Query: 18  PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA----SAAAGSNSWVQV 73
           P L + ++ V  PHN+ A +RTADA G   V  + P  +  T+       A G+   + +
Sbjct: 96  PPLILVLDGVTDPHNLGACLRTADAAGATAV--IVPKDKSATLTPVVRKVACGAAEVIPL 153

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALA 133
                +   +  L+ +G+ ++ T   +   +  + D T P  ++MG E  G+ +      
Sbjct: 154 VAVTNLARTLEKLQQRGLWVVGTA-GEAEQEIYQQDLTGPLVMIMGAEGKGMRRLTREHC 212

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           D  + +PM G V SLNVSVA+ + L+EA RQRQ
Sbjct: 213 DFLVKLPMAGSVSSLNVSVATGVCLFEAVRQRQ 245


>UniRef50_P74261 Uncharacterized tRNA/rRNA methyltransferase slr1673 n=1
           Tax=Synechocystis sp. PCC 6803 RepID=Y1673_SYNY3
          Length = 274

 Score = 70.1 bits (170), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 47/150 (31%), Positives = 81/150 (54%), Gaps = 7/150 (4%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEV----HAVWPGSRMRTMASAAAGSNSWVQVKT 75
           L + +E++  P N+  I+RTA A GV  +      V P S    +  ++AGS+  +  + 
Sbjct: 121 LGLVLERLQDPGNLGTILRTAAATGVEGIWLTADCVDPTSP--KVLRSSAGSSLLLPQQQ 178

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
            +++   +     QG+Q++AT +        EID+ RPT ++ G E  G++   L L   
Sbjct: 179 LQSLPPLLEKFHTQGLQLIAT-VPQATQTLWEIDFQRPTIVIFGSEGQGLSAPVLELTTH 237

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            + IP    V+SLNV++A  ++LYEA+RQ+
Sbjct: 238 QVAIPQAPQVESLNVAIAVGVMLYEARRQQ 267


>UniRef50_D2NQI2 rRNA methylase n=54 Tax=Actinomycetales RepID=D2NQI2_9MICC
          Length = 253

 Score = 69.7 bits (169), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 42/156 (26%), Positives = 77/156 (49%), Gaps = 3/156 (1%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSN 68
           I   L  R+ D  V +E      N+  ++RTA+A+   EVH +    R R     A  ++
Sbjct: 93  IIADLDTRRHDFHVAIENWQHDLNIGTVVRTANAMLAKEVHII---GRRRWNRRGAMVTD 149

Query: 69  SWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQE 128
            +  V+ H TI D VA  +G+G++I+   +  ++V     D  +   ++ GQE  G+++E
Sbjct: 150 RYQHVRHHPTIEDFVAWAQGEGLEIIGIDIFPDSVPLETYDLPKKCVLVFGQEGPGLSEE 209

Query: 129 ALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
             A A   + I   G  +S+N + A+ + ++   R+
Sbjct: 210 LHAAARDTLSIEQFGSTRSMNAATAAGIAMHAWVRR 245


>UniRef50_D0LZ96 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Haliangium
           ochraceum DSM 14365 RepID=D0LZ96_HALO1
          Length = 267

 Score = 69.7 bits (169), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 50/162 (30%), Positives = 80/162 (49%), Gaps = 9/162 (5%)

Query: 6   YARICEMLA--RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASA 63
           YA + +++A  R++P L V ++ V  PHN+ AI+R+A  +G   V  + P  R   ++  
Sbjct: 95  YAALEDLIAAPRQRPALFVALDSVTDPHNLGAIVRSAHVLGADGV--ILPKDRAAQVSGV 152

Query: 64  ----AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
               +AG+   + +     +  A+  LK   + I      + A      D T   C+++G
Sbjct: 153 VTKVSAGATEQIAIAQVTNLARALEQLKQAEVWIAGLAAGEGATSLPAFDATGALCLVLG 212

Query: 120 QEKTGITQEALALADQDIIIPMIGM-VQSLNVSVASALILYE 160
            E TG+        D  I IPM+G  V SLNVSVA+ + LYE
Sbjct: 213 AEGTGLRPLVARTCDFLIEIPMLGAGVGSLNVSVAAGVALYE 254


>UniRef50_C8NEH0 TrmH family RNA methyltransferase n=2 Tax=Granulicatella
           RepID=C8NEH0_9LACT
          Length = 256

 Score = 69.7 bits (169), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 43/151 (28%), Positives = 80/151 (52%), Gaps = 11/151 (7%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHA------VWPGSRMRTMASAAAGSNSWVQVKT 75
           + ++ V  P N+  I+RTADA G   V        ++    +R+M     GS+  + V  
Sbjct: 111 IVLDAVQDPGNLGTIVRTADAAGFDAVVLGTGTVDLYNDKVLRSMQ----GSHFHIPV-F 165

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
              + + +  LK +G+Q+  T L  ++ D+  +       I++G E  G++ + + LAD 
Sbjct: 166 QANLQEYLPILKEKGVQVAVTALHRDSKDYSVLQGATDVAIVVGNEGQGVSDDVIDLADV 225

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            + IP+ G  +SLNVS+ASAL++Y+ +  ++
Sbjct: 226 VVTIPIFGKAESLNVSIASALLMYKTKETKE 256


>UniRef50_Q03G93 rRNA methylase n=1 Tax=Pediococcus pentosaceus ATCC 25745
           RepID=Q03G93_PEDPA
          Length = 255

 Score = 69.3 bits (168), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 41/141 (29%), Positives = 75/141 (53%), Gaps = 5/141 (3%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS---RMRTMASAAAGSNSWVQVKTHRT 78
           + ++ V  P N+  ++RTADA G   V     G+       +  A  GS   +Q+K    
Sbjct: 113 LVLDNVQDPGNIGTMVRTADAAGFTGV-VFGDGTADFYNPKILRAMQGSQYHLQLK-RLN 170

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           +   + + K QG  I  + L +NA D+R+ID      ++MG E  G+++  + + D ++ 
Sbjct: 171 LEKWIRNCKDQGSVIFGSILDENARDYRKIDVPDQFSLIMGNEGNGMSERLIEMTDMNLY 230

Query: 139 IPMIGMVQSLNVSVASALILY 159
           IP+ G  +SLNV+VA+ ++++
Sbjct: 231 IPIKGSAESLNVAVAAGVLMF 251


>UniRef50_Q8EPH3 rRNA methylase n=1 Tax=Oceanobacillus iheyensis RepID=Q8EPH3_OCEIH
          Length = 246

 Score = 69.3 bits (168), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 53/170 (31%), Positives = 85/170 (50%), Gaps = 15/170 (8%)

Query: 3   PTRYARICEM-LARRQPD--LTVCMEQVHKPHNVSAIIRTADAVGVHEVHA------VWP 53
           P     + EM + + Q D  L + ++ +  P N+  IIRTADA GV  V        ++ 
Sbjct: 83  PQGVIAVVEMNIPKVQEDNNLIILLDAIQDPGNMGTIIRTADAAGVDAVVLGDGCVDIFN 142

Query: 54  GSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
              +R    A  GS   + + T  T+   +  L+ QG  ILAT L D AV++ E+     
Sbjct: 143 DKVIR----ATQGSIFHIPIYT-ATLEQEIHMLQTQGFTILATALHD-AVEYTEVSVHNK 196

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
             +++G E  GI    L  A+Q I IP+ G  +SLNV +A+ +++Y  ++
Sbjct: 197 VGLILGNEGAGIAPSLLNKANQRINIPIYGKAESLNVGIAAGILMYHLKK 246


>UniRef50_Q6MMA4 Putative tRNA/rRNA methyltransferase n=1 Tax=Bdellovibrio
           bacteriovorus RepID=Q6MMA4_BDEBA
          Length = 258

 Score = 69.3 bits (168), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 40/147 (27%), Positives = 73/147 (49%), Gaps = 2/147 (1%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVH--AVWPGSRMRTMASAAAGSNSWVQVKTHR 77
           L   ++ +    NV +I RTA+ +G  +++     P      +   A G+  ++  +   
Sbjct: 108 LVFVLDNIRSAFNVGSIFRTAECLGAEKIYLCGYTPLPTQWKVEKTAMGTQEYLAWEEAP 167

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            + + +  LK +G +I+A   + +A D  E   + PT  ++G E+ G+  E L + D+  
Sbjct: 168 KLLECLEELKDEGYRIVALETAASASDLFEKFESEPTAFVLGNERFGLDPEVLKIIDEVR 227

Query: 138 IIPMIGMVQSLNVSVASALILYEAQRQ 164
           IIP+ G   SLNV V +A+  +E  RQ
Sbjct: 228 IIPLRGRKNSLNVGVTAAVAGFEWMRQ 254


>UniRef50_A0L4P9 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Magnetococcus
           sp. MC-1 RepID=A0L4P9_MAGSM
          Length = 246

 Score = 69.3 bits (168), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 49/154 (31%), Positives = 78/154 (50%), Gaps = 7/154 (4%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMAS----AAAGSNSWV 71
           +QP L V ++ V  PHN+ AI+R+A+A G   V  + P  R   + +    A+AG+   +
Sbjct: 94  KQP-LLVILDGVEDPHNLGAIMRSAEAFGALAV--ILPKDRTAPLNAGAIKASAGAAERL 150

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            +     +  A+  L+ + + ++       A     +D   P  ++MG E +G+ +    
Sbjct: 151 DLIRVTNLARAIEQLQQRNVWVIGLAGEAGAPLIGTLDCKGPLALVMGNEGSGLRRLTRE 210

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             DQ   IPM G V SLNVSVA+ + LYE  RQR
Sbjct: 211 RCDQLAAIPMGGGVGSLNVSVATGVALYEVLRQR 244


>UniRef50_B2UR21 RNA methyltransferase, TrmH family, group 3 n=3
           Tax=Chlamydiae/Verrucomicrobia group RepID=B2UR21_AKKM8
          Length = 193

 Score = 68.9 bits (167), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 51/157 (32%), Positives = 75/157 (47%), Gaps = 5/157 (3%)

Query: 12  MLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSNS 69
           +L +    L + ++ V  PHN+ AI+RTAD  GV  V A    S     T+   + G+  
Sbjct: 38  ILDKSSNPLLLILDCVQDPHNLGAILRTADGAGVDAVIAPRDKSVGITETVLRVSVGAAE 97

Query: 70  WVQVKTHRTIGDAVAHLKGQGMQILATHLSDNA-VDFREIDYTRPTCILMGQEKTGITQE 128
            V       +   +  L+ +G+ I  T  SD       E D+T P  ++MG E  G+ + 
Sbjct: 98  KVPFIQVTNLARTMKQLQSRGIWIFGT--SDKGDRGLYETDFTGPAALVMGAEGEGMRRL 155

Query: 129 ALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
                D  + IPM G +  LNVSVA+ + LYE  RQR
Sbjct: 156 TEENCDFLLRIPMKGSIPCLNVSVATGVCLYEMVRQR 192


>UniRef50_Q8DNE3 Possible rRNA/tRNA methylase n=69 Tax=Streptococcaceae
           RepID=Q8DNE3_STRR6
          Length = 252

 Score = 68.9 bits (167), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 47/148 (31%), Positives = 76/148 (51%), Gaps = 5/148 (3%)

Query: 17  QPDLT----VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQ 72
           Q DL+    + +E V  P NV  IIRTADA G   V      + + ++ +  +   S   
Sbjct: 102 QADLSQGKFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFH 161

Query: 73  VKTHRTIGDAVA-HLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
           +  +R    A+    K   + +LAT LS ++VD+RE+       ++MG E  GI+     
Sbjct: 162 LPIYRMTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAE 221

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILY 159
            ADQ + I M G  +SLNV+VA+ ++++
Sbjct: 222 SADQLVHISMKGQAESLNVAVAAGILIF 249


>UniRef50_A1AWI4 RNA methyltransferase, TrmH family, group 3 n=3
           Tax=Gammaproteobacteria RepID=A1AWI4_RUTMC
          Length = 247

 Score = 68.9 bits (167), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 45/144 (31%), Positives = 76/144 (52%), Gaps = 3/144 (2%)

Query: 24  MEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSNSWVQVKTHRTIGD 81
           ++ +  P N+ A +R+A+A GVH V     GS      +   +AG+ + +++     +  
Sbjct: 103 LDSIQDPRNLGACLRSANAAGVHCVVINKNGSAPINSLVHKTSAGALNQLKIFQVTNLSR 162

Query: 82  AVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPM 141
            +  L+ + + ++    S N +   +ID T P  I+MG E +G+ +      DQ   IPM
Sbjct: 163 TIKALQQKNIWVIGLDGSVN-ISIYQIDLTIPNAIIMGAEGSGLRRLTKQSCDQLAKIPM 221

Query: 142 IGMVQSLNVSVASALILYEAQRQR 165
            G V+SLNVSVA+ + L+E  RQR
Sbjct: 222 QGKVESLNVSVATGVTLFEVNRQR 245


>UniRef50_A8DJH5 TsnR n=1 Tax=Candidatus Chloracidobacterium thermophilum
           RepID=A8DJH5_9BACT
          Length = 282

 Score = 68.9 bits (167), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 51/168 (30%), Positives = 84/168 (50%), Gaps = 23/168 (13%)

Query: 18  PDLT-------VCMEQVHKPHNVSAIIRTADAVG-------VHEVHAVWPGSRMRTMASA 63
           PDLT       V  + +  P N+ A+IRTA+A G       V  V    P +       A
Sbjct: 108 PDLTHHPAPLFVLADGIQSPGNLGALIRTAEAAGATGILVTVGTVDPFQPKA-----LRA 162

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           AAGS   + +    ++ D +  L  QG++++   +  +   +   D+ +P  + +G E  
Sbjct: 163 AAGSAFRLPIIAGSSVADELQKLYRQGVRLVTADIHGD-TPYEAFDWRQPVLLWLGSEGH 221

Query: 124 GI---TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           G+   T +        ++IPM G V+SLNV+VA A++LYEA+RQR+ +
Sbjct: 222 GLRSLTDDFKHRLAARLVIPMEGQVESLNVAVAGAILLYEARRQRRQS 269


>UniRef50_Q0VMF8 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Alcanivorax
           RepID=Q0VMF8_ALCBS
          Length = 251

 Score = 68.9 bits (167), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 46/151 (30%), Positives = 77/151 (50%), Gaps = 8/151 (5%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEV-----HAVWPGSRMRTMASAAAGSNSWVQVK 74
           L + +E V  PHN+ A +R+ADA GV  V     +A          A  AA S ++ ++ 
Sbjct: 101 LLLVLENVTDPHNLGACLRSADAAGVQAVIVPRRNAAGLTPVACRTAVGAAESLAYYEIG 160

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
              ++ D    L+ +G+ ++ T L + +             ++MG E +G+ +      D
Sbjct: 161 NLASLLD---QLRDRGVWVVGTALEERSESLFTFQAPESLAVVMGAEGSGLKRLTRDKCD 217

Query: 135 QDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           Q + IPM G VQSLNVSVA+ ++L++ + QR
Sbjct: 218 QLLEIPMAGEVQSLNVSVATGVMLFQVRAQR 248


>UniRef50_B5YF75 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Dictyoglomus
           RepID=B5YF75_DICT6
          Length = 241

 Score = 68.9 bits (167), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 45/151 (29%), Positives = 78/151 (51%), Gaps = 7/151 (4%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA----AGSNSWVQVKT 75
           + V ++ +  PHN+ AI RT++  G   +  V P +R   + SA+    AG+ S++ V  
Sbjct: 93  VIVVLDHIQDPHNLGAIARTSEFAGASAI--VIPKARSAGVTSASFKASAGALSYIPVVR 150

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
              I + +  LK +G  I+   L D    + +++Y  P  +++G E  G+ +      D 
Sbjct: 151 VSNIANFLRELKKKGWFIVGADL-DTENLYNQVNYRFPLALVVGSEDEGLHRIVKESCDL 209

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            + IP  G V+SLNVSVA  +ILY+ +   +
Sbjct: 210 LVKIPSYGKVESLNVSVALGIILYKIRESHE 240


>UniRef50_C6X309 RNA methylase, SpoU family n=1 Tax=Flavobacteriaceae bacterium
           3519-10 RepID=C6X309_FLAB3
          Length = 197

 Score = 68.6 bits (166), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 45/149 (30%), Positives = 77/149 (51%), Gaps = 4/149 (2%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEV--HAVWPGSRMRTMASAAAGSNSWVQV 73
           ++  LTV ++ V   HNV AI RTADA  + +V    + P    R +  AA G+   V+ 
Sbjct: 43  QKTGLTVVLDNVRSMHNVGAIFRTADAFLIEKVVLCGITPQPPHREIHKAALGATESVEW 102

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNA--VDFREIDYTRPTCILMGQEKTGITQEALA 131
               T+  A+  LK +   ++    + N+  +    I   +   +++G E  G++++ALA
Sbjct: 103 IYVDTVSAALETLKKENYTVIGIEQTSNSQKIGDYHISKDQKYAVVLGNEVDGLSEDALA 162

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYE 160
           L D  + IP +G   SLNVSV   ++++E
Sbjct: 163 LYDAFLEIPQLGTKHSLNVSVCGGIVMWE 191


>UniRef50_Q7P601 23S rRNA methyltransferase n=10 Tax=Fusobacterium
           RepID=Q7P601_FUSNV
          Length = 234

 Score = 68.6 bits (166), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 41/153 (26%), Positives = 77/153 (50%), Gaps = 9/153 (5%)

Query: 11  EMLARRQPDLTVCMEQVHKPHNVSAIIRTA-----DAVGVHEVHAVWPGSRMRTMASAAA 65
           E LA +   L + ++++  P N  AIIR+A     D + + E ++V       T+   + 
Sbjct: 80  EELAEKDKSLVLILDEIQDPRNFGAIIRSAEVFKVDLIIIPERNSVRIN---ETVVKTST 136

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G+  +V +     + D +  LK     +      + ++++ E +Y+    +++G E +GI
Sbjct: 137 GAIEYVNISKVTNLSDTINKLKKLDYWVYGAA-GEASINYNEENYSNKIILVLGNEGSGI 195

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALIL 158
            ++     D+ I IPM G + SLNVSVAS ++L
Sbjct: 196 RKKVREHCDKLIKIPMYGQINSLNVSVASGILL 228


>UniRef50_Q2LQ81 23S rRNA Gm2251 methyltransferase n=1 Tax=Syntrophus aciditrophicus
           SB RepID=Q2LQ81_SYNAS
          Length = 249

 Score = 68.6 bits (166), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 50/169 (29%), Positives = 84/169 (49%), Gaps = 13/169 (7%)

Query: 5   RYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR---- 56
           RY  +  ++A R P    DL + ++ +  PHN+ A+IR+A   G + +  + P  R    
Sbjct: 77  RYQDLDAVIANRHPSCPYDLVLILDGILDPHNLGALIRSAHCFGANGI--ILPERRAASV 134

Query: 57  MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQIL-ATHLSDNAVDFREIDYTRPTC 115
             T+   +AG+   + +     +  A+  LK +G  I  A   +D +V   + DY     
Sbjct: 135 TGTVIKTSAGAARHIPIARVANLARALDELKTKGFWIFGADARADQSVS--DPDYQGAVG 192

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           ++MG E  G+        D  I IPM+G + SLNVSV+  +IL+E +R+
Sbjct: 193 LVMGGESKGLRPLIRKKCDDLISIPMLGKIDSLNVSVSGGIILHEIRRK 241


>UniRef50_B4WGA5 RNA methyltransferase, TrmH family, group 3, putative n=1
           Tax=Synechococcus sp. PCC 7335 RepID=B4WGA5_9SYNE
          Length = 365

 Score = 68.6 bits (166), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 47/153 (30%), Positives = 78/153 (50%), Gaps = 8/153 (5%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAAGSNSWV 71
           R+P + V  + +  PHN+ AIIR+A+A+G   +  V P  R      T+A  +AG+   +
Sbjct: 188 RRP-VIVAADGITDPHNLGAIIRSAEAIGAQGI--VIPQRRAVGVTSTVAKVSAGALENI 244

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            +     +G A+ +LK     I     ++ A      D++ P  +++G E +G++     
Sbjct: 245 PIARVINLGRALEYLKSNSFWIYGL-TAEAAQSIHTTDFSAPVVLVVGAEGSGLSLSVQN 303

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           L DQ + I + G   SLN SVA+ + LYE  RQ
Sbjct: 304 LCDQLVSIELSGKTPSLNASVATGMALYEIYRQ 336


>UniRef50_C2BF70 tRNA/rRNA methyltransferase n=1 Tax=Anaerococcus lactolyticus ATCC
           51172 RepID=C2BF70_9FIRM
          Length = 239

 Score = 68.6 bits (166), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 46/149 (30%), Positives = 79/149 (53%), Gaps = 11/149 (7%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA----SAAAGSNSWVQVKTHR 77
           + ++Q+  PHN+ AIIR+A++ G   V  + P  R  +++      +AG+ + + +   +
Sbjct: 92  IILDQIEDPHNLGAIIRSAESFGFDGV--IIPERRSASVSPIVYKTSAGAINNINIIMVK 149

Query: 78  TIGDAVAHLKGQGMQI--LATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
               A+  +K  G  +  LA   S + +D  ++D     C+++G E  G+++      D 
Sbjct: 150 NTNRAIEEIKEAGFWVYGLAGEAS-SPID--QVDLKGKVCLIVGNEGKGLSRLVRENCDI 206

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            I IPM G V SLN SVASA+ +YE  RQ
Sbjct: 207 LINIPMKGFVNSLNASVASAIAMYEVLRQ 235


>UniRef50_B1M5G3 RNA methyltransferase, TrmH family, group 3 n=16 Tax=Bacteria
           RepID=B1M5G3_METRJ
          Length = 281

 Score = 68.6 bits (166), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 49/146 (33%), Positives = 71/146 (48%), Gaps = 9/146 (6%)

Query: 26  QVHKPHNVSAIIRTADAVGVHEV-----HAVWPGSRMRTMASAAAGSNSWVQVKTHRTIG 80
           Q+  PHNV AI+RTA A GV  +     HA  PG+    +A +A+G    V   T R + 
Sbjct: 140 QITDPHNVGAIVRTAAAFGVAGIVTTARHA--PGA-TGVLAKSASGGLEHVPFVTVRNLA 196

Query: 81  DAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIP 140
           +A+  L  +G   +    SD       +   RP  I++G E  G+ +      D    IP
Sbjct: 197 EALIELGERGFTRVGLD-SDAPESLDALTVARPLVIVLGAEGKGLRERTRGCCDVLARIP 255

Query: 141 MIGMVQSLNVSVASALILYEAQRQRQ 166
             G ++SLNVS A+A+ LY   R+R 
Sbjct: 256 FSGAIRSLNVSNAAAITLYALGRKRD 281


>UniRef50_B9KZB6 Possible 23S rRNA methyltransferase tsnR n=1 Tax=Thermomicrobium
           roseum DSM 5159 RepID=B9KZB6_THERP
          Length = 271

 Score = 68.6 bits (166), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 52/157 (33%), Positives = 89/157 (56%), Gaps = 12/157 (7%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS---RMRTMASAAAGSNSWVQV 73
           +P   + ++++  P N+  ++R+A   GVH V  + PG+       +  AAAG++  + +
Sbjct: 114 EPLFALIVDRLQDPGNLGTLLRSALGAGVHAV-LLTPGTVDPFNPKVVRAAAGAHFHLPI 172

Query: 74  KTHRTIGDAVA-HLKGQGMQIL-ATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            T     D VA   +  G++I+ A   +  A D R  D+TR + +++G E  GI+ E   
Sbjct: 173 ATL----DPVAIQREFPGLEIVVARPQALRAYDER--DWTRASAVVIGSEAHGISAELAR 226

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           LA  ++ IP+ G V+SLN  VA ++IL+EA RQR++A
Sbjct: 227 LAADEVRIPLRGGVESLNAGVAGSIILFEAARQRRHA 263


>UniRef50_C6VPS4 rRNA methylase n=8 Tax=Lactobacillales RepID=C6VPS4_LACPJ
          Length = 257

 Score = 68.2 bits (165), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 47/153 (30%), Positives = 80/153 (52%), Gaps = 8/153 (5%)

Query: 17  QPDLT---VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS---RMRTMASAAAGSNSW 70
           Q DLT   + ++ V  P N+  ++RTADA G   V A   G+       +  A  GS   
Sbjct: 107 QLDLTRPWLLLDNVQDPGNIGTMVRTADAAGFAGV-AFGTGTVDIHQPKVERAMQGSQFH 165

Query: 71  VQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEAL 130
           +Q+ +   +   V  L+ QG  +  + L+  A  + +ID      ++MG E  G+++E L
Sbjct: 166 LQLIS-TDLDKLVDQLQAQGSPVYGSELNPQAARYLDIDAPASFGLIMGNEGNGMSRELL 224

Query: 131 ALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           A  DQ++ IP+ G  +SLNV+VA+ ++++   R
Sbjct: 225 ARTDQNLYIPIKGQAESLNVAVAAGVLMFGLYR 257


>UniRef50_B4W7H0 RNA methyltransferase, TrmH family n=1 Tax=Brevundimonas sp. BAL3
           RepID=B4W7H0_9CAUL
          Length = 272

 Score = 68.2 bits (165), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 48/144 (33%), Positives = 73/144 (50%), Gaps = 2/144 (1%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGD 81
           V +EQV  P N+  IIRTADA G   V  +       ++ +  A   S   V   RT  +
Sbjct: 129 VALEQVRDPGNLGTIIRTADAAGCGGVILIGDCVDPYSVEAVRATMGSVFAVSITRTDPE 188

Query: 82  A-VAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIP 140
           A +A  K     ++ T L D  V  R     +P+ ILMG E+ G+T +  A  D ++ IP
Sbjct: 189 AFLAWRKTWPGSVVGTRL-DATVSHRSAVMQKPSLILMGNEQAGLTDQLAAACDVNVKIP 247

Query: 141 MIGMVQSLNVSVASALILYEAQRQ 164
           M G   SLN+++A+ +++Y A  +
Sbjct: 248 MRGRADSLNLAIATGIMVYAATDE 271


>UniRef50_A6DS75 tRNA/rRNA methyltransferase n=1 Tax=Lentisphaera araneosa HTCC2155
           RepID=A6DS75_9BACT
          Length = 168

 Score = 68.2 bits (165), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 45/159 (28%), Positives = 76/159 (47%), Gaps = 8/159 (5%)

Query: 11  EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVH-----AVWPGSRMRTMASAAA 65
           E  A  + ++ V ++++   HNV  I R ADA  V  V+     A  P  ++      A 
Sbjct: 10  ETEASEKVEVIVVLDRLRSAHNVGNIFRLADAANVEAVYTCGYTASPPHPKLE---KTAM 66

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G++ +V  +      +AV  LK  G ++ A    D+A+D  E  ++     + G E  GI
Sbjct: 67  GTDEFVNCEHFDHSLEAVGSLKKNGYRVYAVDTIDSAIDVHEAQFSGKCAFVFGNEALGI 126

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            QE L   D+ I +   G   S+NVS  +A++L++A  +
Sbjct: 127 QQETLEACDEYIRLNAHGRKNSINVSNCAAVVLFQASYK 165


>UniRef50_Q3AXD9 RNA methyltransferase TrmH, group 3 n=19 Tax=Bacteria
           RepID=Q3AXD9_SYNS9
          Length = 652

 Score = 68.2 bits (165), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 46/159 (28%), Positives = 81/159 (50%), Gaps = 9/159 (5%)

Query: 10  CEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAA 65
           C  L   +P L + ++ +  PHN+ A++R+A+A+G H +  V P  R      + A  AA
Sbjct: 376 CSELG--EPPLLLALDGITDPHNLGAVVRSAEAMGAHGL--VLPQRRSAGLTGSAAKVAA 431

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G+   + V     +  ++  LK  G +++    ++  V   ++D   P  ++ G E  G+
Sbjct: 432 GAMEHLPVARVVNLNRSLEKLKDSGYRVIGL-AAEGDVTLMDVDLEGPLVLVTGSEDQGL 490

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           +       DQ + IP+ G+  SLN SVA+AL +YE  R+
Sbjct: 491 SLLTRRHCDQLVRIPLRGITPSLNASVATALCVYEVARR 529


>UniRef50_C6QC90 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Hyphomicrobium
           denitrificans ATCC 51888 RepID=C6QC90_9RHIZ
          Length = 269

 Score = 68.2 bits (165), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 46/140 (32%), Positives = 71/140 (50%), Gaps = 3/140 (2%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGD 81
           V +E++  P N+  I+RTADA G   V  V       ++ +  A   S   V   +    
Sbjct: 124 VALEEIRDPGNLGTIVRTADATGCAGVILVGTTCDPYSLDAVRATMGSIFAVPIVKMERS 183

Query: 82  AVAHL-KGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIP 140
           A   L +     ++ THL+    DFR + Y  P  I+MG E  G++ EA A   + + IP
Sbjct: 184 AFISLQRAWAGDVIGTHLTARE-DFRSL-YREPQLIVMGGEGPGLSSEAAASCTKLVKIP 241

Query: 141 MIGMVQSLNVSVASALILYE 160
           M G + SLN++VA+ L+LY+
Sbjct: 242 MAGKLDSLNLAVATGLMLYQ 261


>UniRef50_B9KYY7 RNA methyltransferase, TrmH family, group 3 n=4 Tax=Chloroflexi
           RepID=B9KYY7_THERP
          Length = 261

 Score = 68.2 bits (165), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 49/167 (29%), Positives = 82/167 (49%), Gaps = 6/167 (3%)

Query: 2   NPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----M 57
           +P  Y     +L      + + ++ +  P N++ ++RTA+A GV  V  V P  R     
Sbjct: 83  SPYPYVDFATLLDPAPESIVLLLDHLQDPQNIATLLRTAEAAGVRGV--VLPERRAAGIT 140

Query: 58  RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
             + +A+AG+   +Q+     +  AV  L+  G  I+A     NA          P  +L
Sbjct: 141 PAVVNASAGAVEHLQITLVTNLARAVDTLREHGYWIVALEPGPNAQSLFRAPLPLPLVLL 200

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           +G E  G++   L  AD  +IIPM+G ++SLN +VA ++ LYE  R+
Sbjct: 201 VGAEGHGLSPVLLKRADVQVIIPMLGQIESLNAAVAGSIALYEIVRR 247


>UniRef50_B8FEV3 RNA methyltransferase, TrmH family, group 3 n=1
           Tax=Desulfatibacillum alkenivorans AK-01
           RepID=B8FEV3_DESAA
          Length = 249

 Score = 68.2 bits (165), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 49/164 (29%), Positives = 81/164 (49%), Gaps = 11/164 (6%)

Query: 11  EMLARR----QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA----S 62
           E+L ++    QP   + M++++ P N  A++RTA   GV+ V  + P  R   ++     
Sbjct: 82  ELLVKKAGGEQPLFFLLMDEINDPQNCGALMRTALCAGVNGV--IMPDKRSSPLSPAVSK 139

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
           A+AG+   + V     +  ++ +LK QG+         +   + E D T P  +++G E 
Sbjct: 140 ASAGALEHMPVARVVNLVRSMQYLKDQGVWFFGLDARASGTVW-EADLTGPAAVVVGNEG 198

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            G+        DQ + IP  G + SLN SVA AL +YE  RQR+
Sbjct: 199 KGLRPLVRKECDQLVSIPQAGPLGSLNASVAGALSMYEVMRQRR 242


>UniRef50_A6BKK3 Putative uncharacterized protein n=6 Tax=Bacteria
           RepID=A6BKK3_9FIRM
          Length = 265

 Score = 67.8 bits (164), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 46/168 (27%), Positives = 82/168 (48%), Gaps = 12/168 (7%)

Query: 6   YARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----M 57
           YA + +ML     + +    + ++ +  PHN+ AIIRTA+  G H V  + P  R     
Sbjct: 100 YAEVEDMLKLAEEKGEDPFLIILDNIEDPHNLGAIIRTANQAGAHGV--IIPKRRAVGLT 157

Query: 58  RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
            T+A  +AG+ ++  V     +   +  LK +G+  +   +  + +   +++   P  ++
Sbjct: 158 ATVARTSAGALNYTPVAKVTNLVKTMEDLKKKGLWFVCADMDGDVM--YDVNMKGPIGLV 215

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +G E  G+ +      D    IPM G + SLN SVA+ ++ YE  RQR
Sbjct: 216 IGNEGEGVGRLVKDTCDFTARIPMKGDIDSLNASVAAGVLAYEIVRQR 263


>UniRef50_D2MNZ0 RNA methyltransferase, TrmH family n=1 Tax=Bulleidia extructa W1219
           RepID=D2MNZ0_9FIRM
          Length = 237

 Score = 67.8 bits (164), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 46/165 (27%), Positives = 80/165 (48%), Gaps = 8/165 (4%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMAS----A 63
           RI + L   +    + +E V  P N   ++RTA + GV  +  + P      + S    +
Sbjct: 75  RIMDHLEISRSSFLLVLEGVVDPFNFGYMVRTAYSAGVDGI--LIPEYHWHDLESVILKS 132

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           +AG+     +   + +   +  LK +G  I A +  DNA+ + E DYT PT   +G E  
Sbjct: 133 SAGAFDHCSIIPSKDLAQDLRLLKEKGFTIYAGY-RDNAIVYDEADYTNPTVFCVGGELR 191

Query: 124 GITQEALALADQDIIIPMI-GMVQSLNVSVASALILYEAQRQRQN 167
           G++++ L   DQ + IP   G   +LN + A ++  +E  RQR++
Sbjct: 192 GLSKQVLEQVDQAVYIPYANGFKNALNAASACSVFCFEVLRQRRH 236


>UniRef50_D1NAJ1 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Victivallis vadensis
           ATCC BAA-548 RepID=D1NAJ1_9BACT
          Length = 273

 Score = 67.8 bits (164), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 46/157 (29%), Positives = 85/157 (54%), Gaps = 12/157 (7%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGV------HEVHAVWPGSRMRTMASAAAGSNS 69
           R   L +  E V KP N+ +++R+ADA GV      ++   ++  + +R  ++ A  S  
Sbjct: 116 RPNGLYLVAEAVEKPGNLGSMLRSADAAGVDGFIICNKCTDIYNPNVIRA-STGALFSVP 174

Query: 70  WVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEA 129
             + +      +A   LK   ++ LA     + + + ++D T+   I++G E+TG+T+  
Sbjct: 175 LAEAENQ----EAYDWLKKNNIRTLAATPHTDQI-YTDVDMTQAVAIVVGTEQTGLTELW 229

Query: 130 LALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           +  +D  + IPM+G + SLNV+ A+ ++LYEA RQR 
Sbjct: 230 MEHSDLPVRIPMLGKIDSLNVATATTILLYEAARQRN 266


>UniRef50_A9KHD7 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Clostridium
           phytofermentans ISDg RepID=A9KHD7_CLOPH
          Length = 264

 Score = 67.8 bits (164), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 43/148 (29%), Positives = 78/148 (52%), Gaps = 3/148 (2%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTHRTI 79
           + +E +  P N+  ++RTA+ VG+  +        M    +  +  G+   V        
Sbjct: 117 LLLEDIRDPGNLGTMVRTAEGVGMTGIVLSKDSVDMFNPKVIRSTMGAIFRVPFFYAEDF 176

Query: 80  GDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIII 139
              +  +K + + I A HL   AV + ++ Y   + IL+G E  G++ +A +L+ Q I I
Sbjct: 177 YACLNQIKNEEIAIYAAHLQ-GAVWYDKVSYQGKSAILIGNEANGLSDKATSLSTQRIKI 235

Query: 140 PMIGMVQSLNVSVASALILYEAQRQRQN 167
           PM G V+SLN ++A+A+++YE+ RQ +N
Sbjct: 236 PMEGNVESLNAAIAAAVLMYESYRQIRN 263


>UniRef50_P94538 Uncharacterized tRNA/rRNA methyltransferase ysgA n=110
           Tax=Bacillales RepID=YSGA_BACSU
          Length = 248

 Score = 67.8 bits (164), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 48/169 (28%), Positives = 84/169 (49%), Gaps = 22/169 (13%)

Query: 3   PTRYARICEM------LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEV------HA 50
           P + A +C M       AR+     + ++ V  P N+  +IRTADA G+  V        
Sbjct: 86  PQQIAAVCHMPEEKLATARK----VLLIDAVQDPGNLGTMIRTADAAGLDAVVLGDGTAD 141

Query: 51  VWPGSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDY 110
            + G  +R+    A GS+  + V   R +   V  LK +G+++  T L  N   ++EI  
Sbjct: 142 AFNGKTLRS----AQGSHFHIPV-VRRNLPSYVDELKAEGVKVYGTALQ-NGAPYQEIPQ 195

Query: 111 TRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILY 159
           +    +++G E  G+    L   D ++ +P+ G  +SLNV+VA+A+++Y
Sbjct: 196 SESFALIVGNEGAGVDAALLEKTDLNLYVPLYGQAESLNVAVAAAILVY 244


>UniRef50_B1ZVF9 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Opitutaceae
           RepID=B1ZVF9_OPITP
          Length = 296

 Score = 67.8 bits (164), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 48/155 (30%), Positives = 80/155 (51%), Gaps = 9/155 (5%)

Query: 18  PDL-----TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSW 70
           PDL      + +E + KP N+  I+R+ADA G   V    P + +    +  A+ G    
Sbjct: 142 PDLQRAPFILVVEAIEKPGNLGTILRSADAAGCDAVIVCDPVTDIFNPNVVRASTGVLFS 201

Query: 71  VQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEAL 130
           V +    +    +A L+ QG++ +AT  +   + + + D   P  I+MG E+ G+++  L
Sbjct: 202 VPLVVAES-APVLAWLRAQGVRTIATTPAAEKL-YTDADLRGPLAIVMGSEQYGLSEFWL 259

Query: 131 ALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
              D  + IPM G   SLNV++A+ + L+EA RQR
Sbjct: 260 KNCDLPVRIPMAGQADSLNVAMATIITLFEAVRQR 294


>UniRef50_D1A2Z2 tRNA/rRNA methyltransferase (SpoU) n=3 Tax=Streptosporangineae
           RepID=D1A2Z2_THECD
          Length = 186

 Score = 67.8 bits (164), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 52/170 (30%), Positives = 75/170 (44%), Gaps = 9/170 (5%)

Query: 1   MNPTRYARICEMLARR-QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM-- 57
           + PT   R+     RR    L + +E V +P NV +I+RT    GV  +   W       
Sbjct: 10  LRPTDVKRLNRAWRRRTHGRLGLIVESVTQPFNVGSIVRTCAVFGVEHL---WLAGNTTP 66

Query: 58  ---RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
              R     A G+   V      T   AV     QG++++A  L+  A+           
Sbjct: 67  PTHRNAGKTALGTERLVPWSQAGTPQQAVREAHDQGLRVIALELAGGAIPLHRAPLEGDV 126

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           C+ +G E  G +   L  AD    IP IG V SLNV+VA+A+ L EA+R+
Sbjct: 127 CLAVGGEDHGCSPALLEAADAVAYIPQIGRVGSLNVAVATAIALAEARRR 176


>UniRef50_A9WFI1 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Chloroflexi (class)
           RepID=A9WFI1_CHLAA
          Length = 261

 Score = 67.8 bits (164), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 45/144 (31%), Positives = 68/144 (47%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGD 81
           V + +V  P N+  I+RTAD  G   V  V   +     A+  A   +    +  RT   
Sbjct: 118 VVLVEVADPGNLGTILRTADGAGFSGVILVGATTDPFDPAAVRASMGALFSQQIARTSWP 177

Query: 82  AVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPM 141
            +     Q    L       A D+R   Y RP  +++G E+ G+T E LA  D  + IPM
Sbjct: 178 DLLTWARQHRIALVGSSDRGASDYRATTYPRPLLLVLGSERHGLTDEQLAACDLVVRIPM 237

Query: 142 IGMVQSLNVSVASALILYEAQRQR 165
            G   SLN++VA+ +++YEA R +
Sbjct: 238 RGRSDSLNLAVAAGILMYEATRSQ 261


>UniRef50_Q027Q7 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Acidobacteria
           RepID=Q027Q7_SOLUE
          Length = 180

 Score = 67.8 bits (164), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 46/148 (31%), Positives = 69/148 (46%), Gaps = 8/148 (5%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVH-----AVWPGSRMRTMASAAAGSNSWVQVKTH 76
           V ++ V   +NV +  RTADA  V +++     A  P S +   A  A  +  W      
Sbjct: 25  VLLDNVRSMYNVGSFFRTADAASVEKLYLSGITAQPPKSAITKTALGAENTVCWEHAWEA 84

Query: 77  RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQD 136
           R +   V   + QG +I A   S +AVD  +     P  ++ G E  GI     AL D  
Sbjct: 85  RPL---VEKARAQGYEIAAVETSVHAVDLFDWTPRFPVLVIFGHEVDGIRPAISALCDTH 141

Query: 137 IIIPMIGMVQSLNVSVASALILYEAQRQ 164
           + IPM+G   SLNV+ A  +++YE  R+
Sbjct: 142 VRIPMLGAKHSLNVATAGGVVIYELLRK 169


>UniRef50_A7HLT3 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Thermotogaceae
           RepID=A7HLT3_FERNB
          Length = 234

 Score = 67.8 bits (164), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 46/147 (31%), Positives = 72/147 (48%), Gaps = 4/147 (2%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTI 79
             V ++QV  P N+ AI+RTA A GV+ V      S   T  S  A + +  ++    T+
Sbjct: 86  FIVLLDQVQDPQNLGAIVRTAVAAGVNMVVLTKDNSAHVTPGSIKASAGTIFRIPIVITV 145

Query: 80  GDA--VAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
             A  +  LK +G+ I    +        E+   RP  I+ G E +GI Q      D+ +
Sbjct: 146 NLARYIEKLKDKGVWIYGADMRGKP--LWEVKLERPLGIVFGNEGSGIRQLVKESCDELV 203

Query: 138 IIPMIGMVQSLNVSVASALILYEAQRQ 164
            IPM   + SLNVSV++ +++YE  R+
Sbjct: 204 SIPMKTPIDSLNVSVSAGILIYEVLRR 230


>UniRef50_C5WEU6 23S rRNA methyltransferase n=2 Tax=Firmicutes RepID=C5WEU6_STRDG
          Length = 245

 Score = 67.4 bits (163), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 1/139 (0%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRT-IG 80
           + +E V  P N+  IIRTADA G   V      + +    +  +   S   +   RT I 
Sbjct: 104 LILEDVQDPGNLGTIIRTADAAGFDGVFLSEKSADVYNSKTLRSMQGSHFHLPIWRTDIY 163

Query: 81  DAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIP 140
                ++     +LAT LS  +VD++ + +     ++MG E  GI+ E   LADQ + I 
Sbjct: 164 KICREMQEHNTPVLATTLSKVSVDYKTVPHQESFALVMGNEGQGISAEMTTLADQLVHIT 223

Query: 141 MIGMVQSLNVSVASALILY 159
           M G  +SLNV+VA+ ++++
Sbjct: 224 MPGQAESLNVAVAAGILIF 242


>UniRef50_A9GVZ1 tRNA/rRNA methyltransferase n=1 Tax=Sorangium cellulosum 'So ce 56'
           RepID=A9GVZ1_SORC5
          Length = 248

 Score = 67.4 bits (163), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 7/151 (4%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP--GSRMRTMAS--AAAGSNSWVQVKT 75
           +TV ++ V  P N  A+IR+A A+G   +  +WP   S   T A+  A+AG+    ++  
Sbjct: 97  ITVALDGVMDPQNFGAVIRSAVALGARAI--LWPEHSSAPLTPATFRASAGAIEHARLCR 154

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
             ++ DA+  L  +G+  +A   +   V+  E+  T P  I++G E  G  +    +   
Sbjct: 155 VPSLPDALEALAARGVAAIALD-AQGPVELGELPLTGPVAIVIGAEDKGTRRSVRRVCQH 213

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
              +PM G + SLN SVA A+ LYE  RQR+
Sbjct: 214 VARLPMTGPISSLNASVAGAIALYEVVRQRR 244


>UniRef50_B8D292 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Halothermothrix orenii H
           168 RepID=B8D292_HALOH
          Length = 270

 Score = 67.4 bits (163), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 43/157 (27%), Positives = 77/157 (49%), Gaps = 14/157 (8%)

Query: 12  MLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSN--- 68
           +   R   + + ++++  P N+  IIRTA A G+  +  +     +  +    A      
Sbjct: 110 LFHNRNRGIILILDRIQDPGNMGTIIRTAVAAGIEGIICLKGSVDIYNLKVIRASMGAIF 169

Query: 69  -----SWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
                + V  K  + I D     K     ++ T L+ +   + EIDY  P  +++G E  
Sbjct: 170 SIPILTGVSFKRLQKIRDEYPDYK-----LICTDLNTSKF-YHEIDYQEPLMLVIGNEAR 223

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYE 160
           GI +E L+LAD  I IP++G + SLN +V++A++LY+
Sbjct: 224 GIREELLSLADIKIKIPLMGNIDSLNAAVSTAIVLYD 260


>UniRef50_Q67QG1 rRNA methyltransferase n=1 Tax=Symbiobacterium thermophilum
           RepID=Q67QG1_SYMTH
          Length = 273

 Score = 67.4 bits (163), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 46/151 (30%), Positives = 72/151 (47%), Gaps = 1/151 (0%)

Query: 18  PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHR 77
           P L + ++ +  P N+   IR+ +A+G                    A  + +      R
Sbjct: 117 PGLVLVLDGLQDPGNLGTAIRSLEAMGGGGAVVAGGVDPYNPKVVRGAMGSLFRLPVVKR 176

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            IGDA+A L+  G +I     +  A+    +D  R   +++G E  G + EA ALAD  +
Sbjct: 177 PIGDALAGLRAAGRRIYLAE-AGGALAPWAVDLARGAAVVVGSEAAGPSPEARALADGVV 235

Query: 138 IIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
            IPM G  +SLN  VA++L+ YEA RQ+  A
Sbjct: 236 SIPMAGPTESLNAGVAASLLAYEAMRQQGAA 266


>UniRef50_A8MI79 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Clostridiaceae
           RepID=A8MI79_ALKOO
          Length = 278

 Score = 67.4 bits (163), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 44/149 (29%), Positives = 79/149 (53%), Gaps = 10/149 (6%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEV----HAVWP-GSRMRTMASAAAGSNSWVQVKTH 76
           V ++++  P N+  IIRTA++     V     +V P  S+       A      +Q    
Sbjct: 124 VILDRIQDPGNMGTIIRTAESANADAVIITKGSVDPYNSKTLRATMGAIFHMPIIQCDDD 183

Query: 77  RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQD 136
           R + D    LK   ++++A  L D    + +IDY     I++G E  GI++  L+  DQ 
Sbjct: 184 RWLDD----LKENEVKLIAADL-DTDKTYIDIDYNTSIGIIIGNEANGISEALLSKVDQR 238

Query: 137 IIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +IIP++G ++SLN SVA+++++Y+A  ++
Sbjct: 239 VIIPILGKIESLNASVAASILIYKAAEEK 267


>UniRef50_A0NWK7 TRNA/rRNA metyltransferase n=1 Tax=Labrenzia aggregata IAM 12614
           RepID=A0NWK7_9RHOB
          Length = 271

 Score = 67.0 bits (162), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 52/151 (34%), Positives = 76/151 (50%), Gaps = 15/151 (9%)

Query: 20  LTVCMEQVHKPHNVSAIIRTA-----DAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVK 74
           L + ++QV  PHNV AI+R+A     DAV   E HA   GS +   AS A      V+VK
Sbjct: 123 LVLALDQVTDPHNVGAILRSAVALDADAVVTTERHAPEEGSVLAKSASGALDMIKHVRVK 182

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQ---EALA 131
               +   +A +K +G   +A   SD      E  ++  T +++G E  G+ Q   EA  
Sbjct: 183 N---MARFIAEMKDEGFSCIALD-SDGPASLEETPFSDKTVLVLGSEGKGVRQGVREACG 238

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
           L  +   + M G ++SLNVS A+ L LY A+
Sbjct: 239 LTAR---LDMPGEIRSLNVSNAAVLSLYVAR 266


>UniRef50_B0S1P7 23S rRNA methyltransferase n=2 Tax=Finegoldia magna
           RepID=B0S1P7_FINM2
          Length = 256

 Score = 67.0 bits (162), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 36/143 (25%), Positives = 70/143 (48%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTH 76
           + D  + +E ++ P N+  IIR+A+A G +++        +    +  +   S  ++   
Sbjct: 107 KSDQILFLENINDPGNLGTIIRSAEAFGYNKIVLSNNSCDIYNSKTIRSAMGSLFRMNIS 166

Query: 77  RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQD 136
               + +   K +G +I  T L  N+    EI       +++G E  GI+ E    AD+ 
Sbjct: 167 YENINVLEKYKSKGFKIYETSLEKNSRSILEIKNKEKHVLIIGNEANGISDEIKKYADEF 226

Query: 137 IIIPMIGMVQSLNVSVASALILY 159
           +IIPM  + +SLN S+A++L ++
Sbjct: 227 LIIPMDNVTESLNASIAASLSMF 249


>UniRef50_C0QAQ0 SpoU n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QAQ0_DESAH
          Length = 291

 Score = 67.0 bits (162), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 37/143 (25%), Positives = 69/143 (48%), Gaps = 1/143 (0%)

Query: 19  DLTVCMEQVHKPHNVSAIIRTADAVGVHE-VHAVWPGSRMRTMASAAAGSNSWVQVKTHR 77
           D  + ++ +    NV +I R+ DA G    +    PG     +   A G+  W+      
Sbjct: 133 DFHIALDGLRSLFNVGSIFRSCDAAGFSSLILGNTPGRENAAVRKTAMGTADWMPHTQTV 192

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            +   +  +K QG  I A   ++ +  + + D+     +++G E+ GI+   LA+ DQ +
Sbjct: 193 DLAQTLVDMKAQGYTITAVETAEQSKPYHDNDWHHRGVLVVGNEEYGISSHVLAVCDQVV 252

Query: 138 IIPMIGMVQSLNVSVASALILYE 160
            IPM G   SLNV+ A+A++++ 
Sbjct: 253 HIPMFGRKNSLNVANAAAILMFH 275


>UniRef50_D1AP92 RNA methyltransferase, TrmH family, group 3 n=7
           Tax=Fusobacteriaceae RepID=D1AP92_SEBTE
          Length = 234

 Score = 67.0 bits (162), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 42/165 (25%), Positives = 79/165 (47%), Gaps = 6/165 (3%)

Query: 6   YARICEMLAR---RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEV--HAVWPGSRMRTM 60
           Y  + E L +   +Q  + + ++Q+  P N  AIIR+A+  GV  +        S   T+
Sbjct: 71  YLELNEFLEKVLAKQRSIVLVLDQIQDPRNFGAIIRSAECFGVDGIIIQDRNSVSVTETV 130

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
             ++ G+   V +     + D++  LK  G  I     +D   ++    +    C+++G 
Sbjct: 131 VKSSTGAIEHVDIIKVTNVSDSMDKLKKYGYFIYGAE-ADGETEYYNEPFPEKLCLVLGS 189

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           E  G+ ++     D+ + IPM G + SLNVSVA+ ++L E  + +
Sbjct: 190 EGKGMRKKVKEHCDKILNIPMHGKINSLNVSVANGILLAEISKNK 234


>UniRef50_A8PMQ1 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Rickettsiella
           grylli RepID=A8PMQ1_9COXI
          Length = 253

 Score = 67.0 bits (162), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 46/154 (29%), Positives = 73/154 (47%), Gaps = 7/154 (4%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAAGSNSWVQ 72
            P   + ++ V  PHN+ A +R+A+A GV  V  + P  R       +   AAG+     
Sbjct: 103 NPPFLLVLDGVQDPHNLGACLRSANAAGVDAV--IIPQDRAVNKTPIVQKTAAGAAEVTS 160

Query: 73  VKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALAL 132
           + T   +   +  LK  G+       S   + + +   T P  +++G E  G+ +     
Sbjct: 161 LFTVTNLATCLERLKKCGIWCYGLDQSGTRLIY-DAPLTGPLALVLGAEGKGLRRLTKVC 219

Query: 133 ADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            D  + IPM+G V SLNVSVA+ + L+E  RQRQ
Sbjct: 220 CDDLVAIPMVGTVGSLNVSVAAGVGLFEVVRQRQ 253


>UniRef50_UPI0001BC4585 23S rRNA methyltransferase n=1 Tax=Fusobacterium sp. D12
           RepID=UPI0001BC4585
          Length = 224

 Score = 66.6 bits (161), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 36/139 (25%), Positives = 68/139 (48%), Gaps = 1/139 (0%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTH-RTIG 80
           + ++ +  P N+  +IR  DA G  ++                +   S   V+ H     
Sbjct: 76  IVLDDIQDPGNLGTMIRLVDAAGFSDIFLTKHSVDCYNEKVVRSSMGSIFHVRLHVMEKK 135

Query: 81  DAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIP 140
           + + +L+ +   +L T L  ++V + E+        + G E  G+++E L LA+Q IIIP
Sbjct: 136 EILEYLQTENYHVLVTTLQRDSVAYTEMQLKEKNAFVFGNEGHGVSKEFLELAEQKIIIP 195

Query: 141 MIGMVQSLNVSVASALILY 159
           + G  +SLNV++A+ +IL+
Sbjct: 196 ISGQAESLNVAMAAGIILF 214


>UniRef50_A3ZYD4 RNA methyltransferase, TrmH family protein n=3 Tax=Bacteria
           RepID=A3ZYD4_9PLAN
          Length = 166

 Score = 66.6 bits (161), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 38/133 (28%), Positives = 65/133 (48%), Gaps = 3/133 (2%)

Query: 32  NVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGM 91
           N+S I+R A    V  V  +  G+ M+     A      + +  HR++   +  LK +G 
Sbjct: 33  NLSRIVRAASCCAVSRV--IVTGN-MKIDPKIARDGAEKLPISRHRSLPPVLKELKSEGY 89

Query: 92  QILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVS 151
           +++    + N+ D     + R T +++G E+ G   + L L D  + IP+ GM  S NV+
Sbjct: 90  RLVGLEQTTNSQDIHHFSFVRNTVLVIGNERQGTPDDVLRLLDDVVEIPVYGMPYSFNVA 149

Query: 152 VASALILYEAQRQ 164
            A+ + LYE  RQ
Sbjct: 150 TATCMALYEFCRQ 162


>UniRef50_Q6ME25 Putative tRNA (Guanosine-2'-O-)-methyltransferase n=1
           Tax=Candidatus Protochlamydia amoebophila UWE25
           RepID=Q6ME25_PARUW
          Length = 246

 Score = 66.6 bits (161), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 41/154 (26%), Positives = 76/154 (49%), Gaps = 9/154 (5%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVH--AVWPGSRMRTMASAAAGSNSWVQVKTHR 77
           +++ ++ +   HNV +IIRT +A  +  ++     P +  + + + + G+  WV+   + 
Sbjct: 90  ISIYLDNLRSAHNVGSIIRTVEAFSLGSIYFSTQTPYTNHKQVQNVSMGAYQWVKCYQNE 149

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            + D           I+A   S+ A++  E  +     +++G E+ G +QE L  A   I
Sbjct: 150 DLNDLT-------QPIIALETSEEAINLYEFIFPEHFTLVVGNEEYGCSQEILTKAHYLI 202

Query: 138 IIPMIGMVQSLNVSVASALILYEAQRQRQNAGMY 171
            IP+ G   SLNV+ A A+   E  RQR+ A +Y
Sbjct: 203 EIPLRGRKNSLNVANAFAITAGEIYRQRKTAKIY 236


>UniRef50_Q2S2J6 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Rhodothermaceae
           RepID=Q2S2J6_SALRD
          Length = 253

 Score = 66.6 bits (161), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 48/176 (27%), Positives = 82/176 (46%), Gaps = 16/176 (9%)

Query: 3   PTRYARICEMLARRQPD---------LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP 53
           P RY  +  ML+   P          + + +++V  P N  A++R+A A G   V  + P
Sbjct: 80  PIRYREVDAMLSDIAPTWDAVQTAQPMLLVVDRVTDPRNFGAMLRSAVAAGTDGV--IVP 137

Query: 54  GSRMRTMASAA----AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREID 109
              M  + +AA    AG+   + +     +   +  LK +G  +     +       + D
Sbjct: 138 TREMAPLNAAAIKASAGTAPRIPIARTDDLPRVLTQLKERGYFVYGAEGTAE-TPLWDAD 196

Query: 110 YTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           + RP  +++G E  G+  E     D+ + IPM G  +SLNVSVA+ L+++EA R R
Sbjct: 197 WDRPVAVVLGSEGQGLAPEVAEACDELLSIPMRGPAESLNVSVATGLLVFEAARSR 252


>UniRef50_Q0EVP7 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Mariprofundus
           ferrooxydans PV-1 RepID=Q0EVP7_9PROT
          Length = 247

 Score = 66.6 bits (161), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 50/154 (32%), Positives = 78/154 (50%), Gaps = 8/154 (5%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEV-----HAVWPGSRMRTMASAAAGSNSWVQVK 74
           + + ++QV  PHN+ A +RTA+A G   V     HA    S +  +A AA G+ S + V 
Sbjct: 97  MVLLLDQVTDPHNLGACVRTAEAAGCAAVIVLKDHAADVHSPV--VAKAACGALSRLPVL 154

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
               +   +  L+ QG   +     +  +   +   +  T ++MG E  G+ +      D
Sbjct: 155 RVINMKRCIEQLQQQGFWTVGL-AGEAELSIYDAKLSGATAVVMGSEDKGVRRLVRETCD 213

Query: 135 QDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           Q I IPM G+V+SLNVSVA+ + L+E  RQR  A
Sbjct: 214 QLIHIPMPGVVESLNVSVATGVALFEINRQRVTA 247


>UniRef50_C6HZU7 TRNA/rRNA methyltransferase (SpoU) n=1 Tax=Leptospirillum
           ferrodiazotrophum RepID=C6HZU7_9BACT
          Length = 259

 Score = 66.2 bits (160), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 47/146 (32%), Positives = 77/146 (52%), Gaps = 8/146 (5%)

Query: 18  PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM----RTMASAAAGSNSWVQV 73
           P   V ++ V  P N+ A++RT DA GV  V  + P  R+    +T+A  +AG+   + +
Sbjct: 111 PSPLVAVDGVQDPRNLGALLRTCDAAGVGGV--LIPRRRVAPLSQTVAKTSAGALFTLPL 168

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALA 133
                +  ++  LK +G  I A  LS + +    +       +++G E+ G+T+  L LA
Sbjct: 169 VRIGNLSGSLRQLKKEGYAIAALDLSGDPLPEGPLPGP--LVLVVGAEEKGVTRPVLDLA 226

Query: 134 DQDIIIPMIGMVQSLNVSVASALILY 159
           D    +PM G VQSLN+SVA+ + LY
Sbjct: 227 DWRFRLPMKGKVQSLNLSVAAGIFLY 252


>UniRef50_Q1IWR8 RNA methyltransferase TrmH, group 3 n=6 Tax=Deinococci
           RepID=Q1IWR8_DEIGD
          Length = 246

 Score = 66.2 bits (160), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 49/158 (31%), Positives = 76/158 (48%), Gaps = 7/158 (4%)

Query: 14  ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVH----EVHAVWPGSRMRTMASAAAGSNS 69
           AR +  L V ++ +  P N  AIIR+A+ +G H    E     P S +  +   AAG+ S
Sbjct: 83  ARGEDLLIVLLDGITDPRNFGAIIRSAEVLGAHGVVVEERRSAPLSPV--VVKTAAGATS 140

Query: 70  WVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEA 129
           ++ V   + +   +  LK  G+ I      + A D    D +    +++G E  G+ +  
Sbjct: 141 YLPVAQTKNLPRLIDALKEDGVWIYGAA-GEAAQDIGRTDLSGKVALVIGAEGEGLRRLV 199

Query: 130 LALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
               D  + IP  G VQSLN SVA+ ++LYEA R R  
Sbjct: 200 REKCDALVRIPTRGQVQSLNASVAAGILLYEAARARDK 237


>UniRef50_C5QRV0 TrmH family rRNA methyltransferase n=3 Tax=Bacillales
           RepID=C5QRV0_STAEP
          Length = 270

 Score = 66.2 bits (160), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 42/142 (29%), Positives = 77/142 (54%), Gaps = 9/142 (6%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS---RMRTMASAAAGSNSWVQVKTHRT 78
           + ++++  P N+  +IRTADA G+ ++  +  G+       +  A+ GS   + V T   
Sbjct: 132 LLIDRIQDPGNLGTLIRTADAAGL-DLIVMEKGTADPYQDKVMRASQGSIFHIPVVTE-- 188

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
             D   ++      +  T L +NAV F+EI+      +L+G E  G+ QE L    +++I
Sbjct: 189 --DLATYMNNFDGPVYGTAL-ENAVSFKEIEAQSTFALLLGNEGEGVNQELLQQTTKNLI 245

Query: 139 IPMIGMVQSLNVSVASALILYE 160
           IP+ G  +SLNV++A +++LY+
Sbjct: 246 IPIYGKAESLNVAIAGSILLYQ 267


>UniRef50_B5CKU5 Putative uncharacterized protein n=1 Tax=Ruminococcus lactaris ATCC
           29176 RepID=B5CKU5_9FIRM
          Length = 279

 Score = 66.2 bits (160), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 49/152 (32%), Positives = 73/152 (48%), Gaps = 13/152 (8%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGV-------HEVHAVWPGSRMRTMASAAAGSNSWVQVK 74
           + ++ +  P N+  I RTA+A G          V    P     TM +       +V   
Sbjct: 133 IVLDNLQDPGNLGTIFRTAEAAGATGILLSSDSVDVYNPKVIRSTMGAVFRMPFFYV--- 189

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
             + +  AV  L  QG++  A HL+   V + E DYT     L+G E  G+  E    AD
Sbjct: 190 --KDLPAAVKSLSSQGIRTYAAHLNGKNV-YDEEDYTEGCAFLIGNEGNGLRDEVSECAD 246

Query: 135 QDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
             I IPM G  +SLN +VA+A++++EA RQR+
Sbjct: 247 CLIRIPMCGKAESLNAAVAAAVLMFEAGRQRR 278


>UniRef50_Q1J4P0 23S rRNA Gm2251 methyltransferase n=42 Tax=Lactobacillales
           RepID=Q1J4P0_STRPF
          Length = 257

 Score = 66.2 bits (160), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 47/167 (28%), Positives = 79/167 (47%), Gaps = 8/167 (4%)

Query: 4   TRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRT 59
           T    I E+  +    L + ++ +  PHN+ +I+RTADA  V  V  + P  R       
Sbjct: 95  TDVDEILEIAEQEANPLILILDGLTDPHNLGSILRTADATNVCGV--IIPKHRSVGVTPV 152

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
           ++  + G+   + +     +   +  LK +G  I  T ++    D    +      +++G
Sbjct: 153 VSKTSTGAVEHIPIARVTNLSQTLDKLKARGFWIFGTDMNGTPSDCWNTN--GKLALVIG 210

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            E  GI+       D+ I IPM G VQSLN SVA+A+++YE  R R+
Sbjct: 211 NEGKGISTNIKKQVDEMITIPMNGHVQSLNASVAAAILMYEVFRNRR 257


>UniRef50_D0JBH4 SpoU rRNA methylase family protein n=2 Tax=Blattabacterium
           RepID=D0JBH4_BLASB
          Length = 267

 Score = 66.2 bits (160), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 43/158 (27%), Positives = 80/158 (50%), Gaps = 16/158 (10%)

Query: 19  DLTVCMEQVHKPHNVSAIIRTADAVGVHEV------HAVWPGSRMRTMASAAAGSNSWVQ 72
            L + ++ + KP N+ A++RTADA G+H +        ++  + +R    +      +++
Sbjct: 111 SLILILDGIEKPGNIGAMLRTADAAGIHIIILCNMKTHIYNSNVIRCSLGSVFTRKIFIE 170

Query: 73  VKTHRTIGDAVAHLKGQGMQILAT----HLSDNAVDFREIDYTRPTCILMGQEKTGITQE 128
                 +G  ++ L+   ++I+ T    H     +   +++Y+    I+ G E  GI+  
Sbjct: 171 -----KMGSIISWLQENKVKIVGTGFYNHQKAKNLYKTKLNYSN-LAIIFGSENKGISNI 224

Query: 129 ALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
              +A++ I IPM G V SLNVS A ++I+YE  RQR 
Sbjct: 225 WFNIANKIITIPMFGNVDSLNVSHAMSIIIYEIIRQRN 262


>UniRef50_P74328 Uncharacterized tRNA/rRNA methyltransferase slr0955 n=1
           Tax=Synechocystis sp. PCC 6803 RepID=Y955_SYNY3
          Length = 384

 Score = 66.2 bits (160), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 7/148 (4%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM----RTMASAAAGSNSWVQVKTHR 77
           + ++ +  PHN+ AIIRTA+A G   +  V P  R+     T+   AAG+     V    
Sbjct: 220 IIIDSITDPHNLGAIIRTAEAFGAQGM--VLPQRRVAGITSTVMKVAAGALEHFPVARVV 277

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            +  A+  LK  G  I  T ++       + D   P  +++G E  G++       D  I
Sbjct: 278 NLSRALETLKESGFWIYGT-VAGKQTALHQADLREPMGLVIGSEGEGLSLLTQKHCDHLI 336

Query: 138 IIPMIGMVQSLNVSVASALILYEAQRQR 165
            IP+ G   SLN SVA+A+ LYE  RQR
Sbjct: 337 TIPLAGKTPSLNASVAAAISLYEIFRQR 364


>UniRef50_B3L269 SpoU rRNA Methylase, putative n=3 Tax=Plasmodium RepID=B3L269_PLAKH
          Length = 264

 Score = 66.2 bits (160), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 42/148 (28%), Positives = 72/148 (48%), Gaps = 7/148 (4%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAA--GSNSWVQV 73
           + P + V +  + K  N+ +I+R+  A GV ++  V   SR R   +     G+  ++ +
Sbjct: 24  KCPQMYVAIYNIGKKKNIGSIVRSCVAFGVSKIFVV---SRKRNEINFFGQMGTCKYITI 80

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDY-TRPTCILMGQEKTGITQEALAL 132
           +    + +   HL    + + A  ++D A+      +  + T  L G E TGI  E L+ 
Sbjct: 81  EYFSNMKELRIHLANNNILLYACEITDRAIAVTRTPFVNKDTAFLFGNEGTGINDETLSY 140

Query: 133 ADQDIIIPMIGM-VQSLNVSVASALILY 159
            D+ I IP  G    SLNVSV+ A+IL+
Sbjct: 141 CDKIIYIPQYGNGTCSLNVSVSCAIILH 168


>UniRef50_C4ZPQ7 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Thauera sp. MZ1T
           RepID=C4ZPQ7_THASP
          Length = 277

 Score = 65.9 bits (159), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 48/156 (30%), Positives = 78/156 (50%), Gaps = 17/156 (10%)

Query: 22  VCMEQVHKPHNVSAIIRTADAVGVHEVHAV--------WPGSRMRTMASAAAGSNSWVQV 73
           + ++ V  P N+ +++RTA A G+   HA+        W    +R    A  G+   V++
Sbjct: 122 IVVDGVQDPGNLGSLLRTAAAAGIR--HALLGEGCAQAWSPRALR----AGMGAQFVVRI 175

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALA 133
           +    +   +A L+      LAT L ++A    E+D   P   L G E  G++   LA A
Sbjct: 176 EEGCEL---LARLESYPGLCLATALREDAHPLYELDLRGPVAWLFGAEGQGLSPALLARA 232

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
           D  +IIPM   ++SLNV+ A+A+ L+E  RQ +  G
Sbjct: 233 DGCVIIPMTAGIESLNVAAAAAVCLFEQARQLRATG 268


>UniRef50_A7B5E9 Putative uncharacterized protein n=7 Tax=Bacteria
           RepID=A7B5E9_RUMGN
          Length = 275

 Score = 65.5 bits (158), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 50/156 (32%), Positives = 78/156 (50%), Gaps = 14/156 (8%)

Query: 18  PDLTVCMEQVHKPHNVSAIIRTADAVGVHE-------VHAVWPGSRMRTMASAAAGSNSW 70
           P L + ++ +  P N+  I RTA+A GV         V    P +   TM   A     +
Sbjct: 126 PHLMI-LDNLQDPGNLGTIFRTAEAAGVTGIIMSRDCVDIYNPKTIRSTMG--ALYRMPF 182

Query: 71  VQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEAL 130
           V V+  R   + +  LK + ++  A HL D    + + DY + T  L+G E  G+ +E  
Sbjct: 183 VYVEDLR---ETIHTLKEKNIKSYAAHL-DGKNTYDKEDYRQGTAFLIGNEGNGLREEIA 238

Query: 131 ALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
             AD  I IPM G V+SLN +VA+ ++++E  RQR+
Sbjct: 239 QCADTWIRIPMCGQVESLNAAVAATVLMFEVSRQRR 274


>UniRef50_A2C1X9 RNA methyltransferase TrmH, group 3 n=6 Tax=Cyanobacteria
           RepID=A2C1X9_PROM1
          Length = 442

 Score = 65.5 bits (158), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 43/150 (28%), Positives = 77/150 (51%), Gaps = 7/150 (4%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAAGSNSWVQVKT 75
           L + ++ +  P N+ AIIR+A+A+G   +  + P  R      ++A  AAG+   + V  
Sbjct: 271 LLLALDGLTDPQNLGAIIRSAEALGAQGL--ILPQRRSAGLTGSVAKVAAGALEHLPVAR 328

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
              +  ++  LK +G  ++     + +    EI +  P  +++G E  GI+     L DQ
Sbjct: 329 VVNLNRSLEKLKDEGYTVVGL-AEEGSSTLSEIKFQGPLVVVVGSEDKGISLITRRLCDQ 387

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            + IP+ G+  SLN SVA+++ LYE  R +
Sbjct: 388 LVRIPLKGVTTSLNASVATSIFLYEVARSK 417


>UniRef50_A6CBV4 YacO n=1 Tax=Planctomyces maris DSM 8797 RepID=A6CBV4_9PLAN
          Length = 261

 Score = 65.5 bits (158), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 46/172 (26%), Positives = 89/172 (51%), Gaps = 12/172 (6%)

Query: 1   MNPTRYARICEMLARRQ--PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
           M P  Y  I E+  +++    L + ++++  P N  AIIR+A+ +G      ++ G+  +
Sbjct: 92  MAPFPYTSI-ELFNQQEITSPLFLILDRIQDPFNFGAIIRSAEIMGAD---GIFSGTHEQ 147

Query: 59  TMASA-----AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
              ++     +AG+ + V +     +       K  G+ I+ T +  +     + ++ +P
Sbjct: 148 CEVTSLVCRTSAGAVNHVPLVQATDLVSLCRDWKQNGINIVGTAMQASE-KLNDYNFQQP 206

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           T +++G E TGI+ E  A     + IP  G  +SLNV+V+++++LYEA RQR
Sbjct: 207 TAVIVGNEGTGISPELQAECTHLVRIPQQGKTESLNVAVSASILLYEASRQR 258


>UniRef50_C9XLS4 Putative RNA methylase n=9 Tax=Clostridium RepID=C9XLS4_CLODC
          Length = 265

 Score = 65.5 bits (158), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 40/155 (25%), Positives = 81/155 (52%), Gaps = 14/155 (9%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHA------VWPGSRMRTMASAAAGSNS 69
           ++    + ++++  P N+  IIRTAD+ GV  + A      ++    +R+   +    N 
Sbjct: 115 KKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPKVIRSTMGSIFDMN- 173

Query: 70  WVQVKTHRTIGDAVAHLKGQGMQILATHL-SDNAVDFREIDYTRPTCILMGQEKTGITQE 128
            +      T    V  LK     I++++L ++N  D  +IDY     +++G E  GI +E
Sbjct: 174 IIDASQDET----VDMLKSLDFNIVSSYLNTENFYD--KIDYGSKVALVIGNEANGINEE 227

Query: 129 ALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
            ++ +D  + IP+ G  +SLN +++SA+++YE ++
Sbjct: 228 LVSKSDILVKIPIYGKAESLNAAISSAILMYEIKK 262


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_P0AGJ3 tRNA guanosine-2'-O-methyltransferase n=231 Tax=...   350   2e-95
UniRef50_Q0VRD7 RNA methyltransferase, TrmH family, group 3 n=2 ...   288   1e-76
UniRef50_Q15Z06 tRNA (Guanosine-2'-O-)-methyltransferase n=2 Tax...   285   7e-76
UniRef50_B5JS83 tRNA (Guanosine-2-O)-methyltransferase n=3 Tax=B...   282   6e-75
UniRef50_C5BJC4 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Ga...   277   2e-73
UniRef50_A1U493 tRNA guanosine-2'-O-methyltransferase n=3 Tax=Ga...   274   1e-72
UniRef50_C7R944 tRNA guanosine-2'-O-methyltransferase n=1 Tax=Ka...   272   7e-72
UniRef50_A3IM41 RRNA methylase SpoU n=1 Tax=Cyanothece sp. CCY01...   266   3e-70
UniRef50_Q7TV55 tRNA/rRNA methyltransferase (SpoU) n=34 Tax=cell...   266   3e-70
UniRef50_Q1N3Z0 Putative tRNA/rRNA methyltransferase n=1 Tax=Ber...   266   3e-70
UniRef50_Q0AB97 tRNA guanosine-2'-O-methyltransferase n=2 Tax=Ec...   260   3e-68
UniRef50_A4SEW2 tRNA guanosine-2'-O-methyltransferase n=10 Tax=C...   259   6e-68
UniRef50_C1XS02 rRNA methylase n=2 Tax=Bacteria RepID=C1XS02_9DEIN    257   2e-67
UniRef50_B3QXG6 tRNA guanosine-2'-O-methyltransferase n=1 Tax=Ch...   253   3e-66
UniRef50_A4BEK2 Putative tRNA methyltransferase n=1 Tax=Reinekea...   229   6e-59
UniRef50_O67577 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Ba...   228   1e-58
UniRef50_C7PC85 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Chiti...   226   6e-58
UniRef50_B8IYB0 tRNA guanosine-2'-O-methyltransferase n=14 Tax=D...   216   6e-55
UniRef50_B9L1B3 tRNA guanosine-2'-O-methyltransferase n=3 Tax=Ba...   214   1e-54
UniRef50_A6LPP3 RNA methyltransferase, TrmH family, group 3 n=35...   212   8e-54
UniRef50_A6Q996 tRNA (Guanosine-2'-O-)-methyltransferase n=2 Tax...   209   6e-53
UniRef50_A9BJB6 RNA methyltransferase, TrmH family, group 3 n=3 ...   208   1e-52
UniRef50_Q4L3J1 Putative trmH family tRNA/rRNA methyltransferase...   207   2e-52
UniRef50_B0K5F8 RNA methyltransferase, TrmH family, group 3 n=51...   207   2e-52
UniRef50_C9LMK8 RNA methyltransferase, TrmH family, group 3 n=1 ...   207   2e-52
UniRef50_C9RX94 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Geoba...   206   5e-52
UniRef50_Q2JI19 RNA methyltransferase, TrmH family, group 3 n=2 ...   206   6e-52
UniRef50_Q5HIE3 Putative trmH family tRNA/rRNA methyltransferase...   205   8e-52
UniRef50_Q9JZR3 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   205   8e-52
UniRef50_Q1J4P0 23S rRNA Gm2251 methyltransferase n=42 Tax=Lacto...   205   9e-52
UniRef50_C8P2I4 23S rRNA (Guanosine-2'-O-)-methyltransferase Rlm...   205   9e-52
UniRef50_Q0AUG1 Conserved hypothetical tRNA/rRNA methyltransfera...   205   1e-51
UniRef50_C2HJX9 tRNA/rRNA methyltransferase n=3 Tax=Clostridiale...   205   1e-51
UniRef50_C4L0U6 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Ba...   205   1e-51
UniRef50_Q7MH13 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   204   2e-51
UniRef50_Q5HRM1 Putative trmH family tRNA/rRNA methyltransferase...   204   2e-51
UniRef50_B2A4B9 RNA methyltransferase, TrmH family, group 3 n=1 ...   204   2e-51
UniRef50_C3RMB5 23S rRNA methyltransferase n=5 Tax=Bacteria RepI...   203   3e-51
UniRef50_P74328 Uncharacterized tRNA/rRNA methyltransferase slr0...   203   4e-51
UniRef50_B3QM30 RNA methyltransferase, TrmH family, group 3 n=12...   203   4e-51
UniRef50_Q73MR5 RNA methyltransferase, TrmH family, group 3 n=1 ...   202   8e-51
UniRef50_Q1G8Z2 TRNA/rRNA methyltransferase n=109 Tax=Bacilli Re...   202   8e-51
UniRef50_A3DH38 RNA methyltransferase, TrmH family, group 3 n=14...   201   1e-50
UniRef50_B0TC37 RNA methyltransferase, trmh family n=1 Tax=Helio...   201   1e-50
UniRef50_A2U211 SpoU rRNA methylase family protein n=1 Tax=Polar...   201   1e-50
UniRef50_B2IX93 RNA methyltransferase, TrmH family, group 3 n=1 ...   201   1e-50
UniRef50_Q606P1 RNA methyltransferase, TrmH family, group 3 n=1 ...   201   2e-50
UniRef50_Q06753 Putative trmH family tRNA/rRNA methyltransferase...   200   2e-50
UniRef50_Q88DE7 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   200   3e-50
UniRef50_B0P8C0 Putative uncharacterized protein n=2 Tax=Clostri...   200   4e-50
UniRef50_B2UR21 RNA methyltransferase, TrmH family, group 3 n=3 ...   200   4e-50
UniRef50_C5CF29 RNA methyltransferase, TrmH family, group 3 n=7 ...   200   4e-50
UniRef50_Q1D7V2 RNA methyltransferase, TrmH family, group 3 n=7 ...   199   5e-50
UniRef50_C4V0H0 tRNA/rRNA methyltransferase n=1 Tax=Selenomonas ...   199   5e-50
UniRef50_B8D0A6 RNA methyltransferase n=11 Tax=Firmicutes RepID=...   199   6e-50
UniRef50_Q82XD1 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   199   6e-50
UniRef50_C5NV68 RNA methyltransferase, TrmH family, group 3 n=1 ...   199   7e-50
UniRef50_C8WTZ2 RNA methyltransferase, TrmH family, group 3 n=2 ...   198   1e-49
UniRef50_B8HJN1 RNA methyltransferase, TrmH family, group 3 n=6 ...   198   1e-49
UniRef50_Q7NYX3 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   198   1e-49
UniRef50_Q7MBB6 tRNA/rRNA methyltransferase n=1 Tax=Gloeobacter ...   198   1e-49
UniRef50_Q1ISZ4 RNA methyltransferase TrmH, group 3 n=2 Tax=Acid...   198   1e-49
UniRef50_A1HPG2 TRNA/rRNA methyltransferase (SpoU) n=1 Tax=Therm...   197   2e-49
UniRef50_B8G1U5 RNA methyltransferase, TrmH family, group 3 n=4 ...   197   2e-49
UniRef50_A8PMQ1 RNA methyltransferase, TrmH family, group 3 n=1 ...   197   2e-49
UniRef50_A8RFN1 Putative uncharacterized protein n=2 Tax=Erysipe...   197   2e-49
UniRef50_Q2LQ81 23S rRNA Gm2251 methyltransferase n=1 Tax=Syntro...   197   2e-49
UniRef50_A6CBV4 YacO n=1 Tax=Planctomyces maris DSM 8797 RepID=A...   197   3e-49
UniRef50_B5EQA2 RNA methyltransferase, TrmH family, group 3 n=3 ...   196   4e-49
UniRef50_A0L4P9 RNA methyltransferase, TrmH family, group 3 n=1 ...   196   5e-49
UniRef50_Q83CW6 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   196   7e-49
UniRef50_C7REQ2 RNA methyltransferase, TrmH family, group 3 n=4 ...   195   8e-49
UniRef50_A4XJ85 RNA methyltransferase, TrmH family, group 3 n=2 ...   195   9e-49
UniRef50_Q14PR4 Putative trna/rrna methyltransferase protein n=1...   195   1e-48
UniRef50_Q724H1 RNA methyltransferase, TrmH family, group 3 n=21...   195   1e-48
UniRef50_Q9LXE4 rRNA methylase-like protein n=11 Tax=Magnoliophy...   194   1e-48
UniRef50_D1AP92 RNA methyltransferase, TrmH family, group 3 n=7 ...   194   3e-48
UniRef50_A7HLT3 RNA methyltransferase, TrmH family, group 3 n=2 ...   193   3e-48
UniRef50_C7H0N3 RNA methyltransferase, TrmH family n=1 Tax=Eubac...   193   3e-48
UniRef50_D1U4M7 tRNA guanosine-2'-O-methyltransferase n=1 Tax=De...   193   5e-48
UniRef50_C8WR00 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Bacil...   192   5e-48
UniRef50_A6BKK3 Putative uncharacterized protein n=6 Tax=Bacteri...   192   5e-48
UniRef50_C1F8Y2 RNA methyltransferase, TrmH family, group 3 n=1 ...   192   6e-48
UniRef50_C2BF70 tRNA/rRNA methyltransferase n=1 Tax=Anaerococcus...   192   7e-48
UniRef50_C0GIN0 RNA methyltransferase, TrmH family, group 3 n=1 ...   192   7e-48
UniRef50_Q1LSR1 RNA methyltransferase, TrmH family, group 3 n=4 ...   192   8e-48
UniRef50_B7DP24 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Alicy...   191   1e-47
UniRef50_B9ZJH8 RNA methyltransferase, TrmH family, group 3 n=1 ...   191   2e-47
UniRef50_A1AWI4 RNA methyltransferase, TrmH family, group 3 n=3 ...   191   2e-47
UniRef50_A2C1X9 RNA methyltransferase TrmH, group 3 n=6 Tax=Cyan...   191   2e-47
UniRef50_Q0EVP7 RNA methyltransferase, TrmH family, group 3 n=1 ...   191   2e-47
UniRef50_A7B5E9 Putative uncharacterized protein n=7 Tax=Bacteri...   190   3e-47
UniRef50_Q1JXE5 RNA methyltransferase TrmH, group 3 n=1 Tax=Desu...   190   3e-47
UniRef50_B8I1W5 RNA methyltransferase, TrmH family, group 3 n=5 ...   190   3e-47
UniRef50_B5YID5 RNA methyltransferase, TrmH family, group 3 n=1 ...   190   4e-47
UniRef50_Q31FJ2 RNA methyltransferase TrmH, group 3 n=1 Tax=Thio...   189   6e-47
UniRef50_A4GI27 rRNA methyltransferase n=1 Tax=uncultured marine...   189   6e-47
UniRef50_D2RLA3 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Acida...   189   8e-47
UniRef50_Q1NS81 RNA methyltransferase TrmH, group 3 n=3 Tax=Delt...   189   8e-47
UniRef50_A1APM1 RNA methyltransferase, TrmH family, group 3 n=8 ...   189   8e-47
UniRef50_A5IXH9 tRNA/rRNA methyltransferase n=1 Tax=Mycoplasma a...   189   9e-47
UniRef50_A3HSD9 SpoU protein (SpoU) n=1 Tax=Algoriphagus sp. PR1...   188   1e-46
UniRef50_Q6FF50 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   188   1e-46
UniRef50_B1X411 tRNA/rRNA methyltransferase (SpoU):RNA methyltra...   188   1e-46
UniRef50_Q7P601 23S rRNA methyltransferase n=10 Tax=Fusobacteriu...   187   2e-46
UniRef50_C0Z9E4 Putative RNA methyltransferase n=1 Tax=Brevibaci...   187   2e-46
UniRef50_C9KPX8 RNA methyltransferase, TrmH family n=1 Tax=Mitsu...   187   2e-46
UniRef50_B2S257 Possible rRNA methylase n=3 Tax=Treponema RepID=...   187   2e-46
UniRef50_C6CVT7 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Bacil...   187   3e-46
UniRef50_A6L4B5 tRNA/rRNA methyltransferase n=16 Tax=Bacteroidet...   186   4e-46
UniRef50_Q31LC0 RNA methyltransferase TrmH, group 3 n=22 Tax=Bac...   186   4e-46
UniRef50_B2V596 RNA methyltransferase, TrmH family n=7 Tax=Clost...   186   4e-46
UniRef50_B0K3L2 tRNA/rRNA methyltransferase (SpoU) n=11 Tax=Ther...   186   4e-46
UniRef50_A9S3U1 Predicted protein (Fragment) n=2 Tax=Physcomitre...   186   5e-46
UniRef50_B8FEV3 RNA methyltransferase, TrmH family, group 3 n=1 ...   186   5e-46
UniRef50_C2KW83 Possible RNA methyltransferase n=1 Tax=Oribacter...   186   5e-46
UniRef50_Q87D65 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   186   6e-46
UniRef50_D2REE3 RNA methyltransferase, TrmH family, group 3 n=1 ...   186   7e-46
UniRef50_D0GJ12 RNA methyltransferase, TrmH family, group 3 n=3 ...   184   1e-45
UniRef50_C7G6D1 RNA methyltransferase, TrmH family n=5 Tax=Clost...   184   1e-45
UniRef50_Q3AXD9 RNA methyltransferase TrmH, group 3 n=19 Tax=Bac...   184   2e-45
UniRef50_A7HIF7 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Anaer...   184   2e-45
UniRef50_A5UYW3 RNA methyltransferase, TrmH family, group 3 n=4 ...   184   2e-45
UniRef50_C6X1H8 rRNA methylase n=4 Tax=Bacteroidetes RepID=C6X1H...   184   2e-45
UniRef50_B0TZ81 tRNA/rRNA methyltransferase n=20 Tax=Francisella...   184   3e-45
UniRef50_D1CD69 RNA methyltransferase, TrmH family, group 3 n=1 ...   184   3e-45
UniRef50_C2FZ75 Possible tRNA/rRNA methyltransferase n=2 Tax=Sph...   184   3e-45
UniRef50_A8STN2 Putative uncharacterized protein n=2 Tax=Clostri...   183   4e-45
UniRef50_B1C951 Putative uncharacterized protein n=1 Tax=Anaerof...   183   4e-45
UniRef50_Q1IWR8 RNA methyltransferase TrmH, group 3 n=6 Tax=Dein...   183   4e-45
UniRef50_UPI0001C31319 RNA methyltransferase, TrmH family, group...   183   4e-45
UniRef50_B4U792 RNA methyltransferase, TrmH family, group 3 n=9 ...   182   5e-45
UniRef50_D2QM84 RNA methyltransferase, TrmH family, group 3 n=2 ...   182   6e-45
UniRef50_Q2RFM6 RNA methyltransferase TrmH, group 3 n=2 Tax=Clos...   182   9e-45
UniRef50_B1GZS4 23S rRNA (Guanosine-2'-O-)-methyltransferase n=1...   182   9e-45
UniRef50_C8N9X3 23S rRNA (Guanosine-2'-O-)-methyltransferase Rlm...   182   9e-45
UniRef50_B4WGA5 RNA methyltransferase, TrmH family, group 3, put...   181   1e-44
UniRef50_C4G1K9 Putative uncharacterized protein n=1 Tax=Abiotro...   181   1e-44
UniRef50_Q2S2J6 RNA methyltransferase, TrmH family, group 3 n=2 ...   181   2e-44
UniRef50_B1AIB3 RNA methyltransferase, TrmH family, group 3 n=15...   181   2e-44
UniRef50_C2D9C1 Possible tRNA/rRNA methyltransferase n=1 Tax=Ato...   181   2e-44
UniRef50_B3ETE6 Putative uncharacterized protein n=1 Tax=Candida...   181   2e-44
UniRef50_A4J4Z3 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Desul...   181   2e-44
UniRef50_C4Z380 RNA methyltransferase, TrmH family n=1 Tax=Eubac...   181   2e-44
UniRef50_B5YF75 RNA methyltransferase, TrmH family, group 3 n=2 ...   181   2e-44
UniRef50_B1I0T3 RNA methyltransferase, TrmH family, group 3 n=2 ...   180   3e-44
UniRef50_A8ZSH6 RNA methyltransferase, TrmH family, group 3 n=1 ...   180   3e-44
UniRef50_C1ZH70 rRNA methylase, putative, group 3 n=1 Tax=Planct...   180   4e-44
UniRef50_C4ZGM4 RNA methyltransferase, TrmH family, group 3 n=8 ...   180   4e-44
UniRef50_Q11YB9 tRNA/rRNA methyltransferase, TrmH family n=24 Ta...   179   5e-44
UniRef50_B1GYT1 23S rRNA methyltransferase n=1 Tax=uncultured Te...   179   6e-44
UniRef50_D1R5P1 Putative uncharacterized protein n=1 Tax=Parachl...   179   7e-44
UniRef50_Q112U6 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Oscil...   179   8e-44
UniRef50_Q7VQP0 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   179   9e-44
UniRef50_Q6AJ92 Related to tRNA/rRNA methyltransferase n=1 Tax=D...   178   1e-43
UniRef50_C1TM87 rRNA methylase, putative, group 3 n=1 Tax=Dethio...   178   1e-43
UniRef50_A5F9W1 tRNA/rRNA methyltransferase (SpoU) n=16 Tax=Bact...   178   1e-43
UniRef50_C4L451 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Exigu...   178   1e-43
UniRef50_B5JMU7 RNA methyltransferase, TrmH family n=1 Tax=Verru...   178   1e-43
UniRef50_B3PM16 SpoU class tRNA/rRNA methyltransferase n=1 Tax=M...   177   2e-43
UniRef50_B6IRN7 RNA methyltransferase, TrmH family, group 3 n=4 ...   177   2e-43
UniRef50_B1I4I6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Candi...   177   2e-43
UniRef50_D1VT15 RNA methyltransferase, TrmH family, group 3 n=1 ...   177   3e-43
UniRef50_Q84X80 CR004 protein n=1 Tax=Chlamydomonas reinhardtii ...   177   4e-43
UniRef50_Q6MNP1 Putative RNA methylase n=1 Tax=Bdellovibrio bact...   176   4e-43
UniRef50_C9RBD1 RNA methyltransferase, TrmH family, group 3 n=1 ...   176   5e-43
UniRef50_A2U3D3 SpoU rRNA methylase n=2 Tax=Flavobacteriaceae Re...   176   5e-43
UniRef50_B3RWG3 Putative uncharacterized protein n=1 Tax=Trichop...   176   5e-43
UniRef50_C7MMG3 rRNA methylase, putative, group 3 n=1 Tax=Crypto...   176   6e-43
UniRef50_Q3A6R3 rRNA methyltranferase n=2 Tax=Desulfuromonadales...   176   6e-43
UniRef50_C7H9L6 RNA methyltransferase, TrmH family, group 3 n=3 ...   176   6e-43
UniRef50_D1Y8A8 RNA methyltransferase, TrmH family, group 3 (Fra...   175   7e-43
UniRef50_B8DUY4 tRNA/rRNA methyltransferase n=5 Tax=Bifidobacter...   175   8e-43
UniRef50_O51468 Uncharacterized tRNA/rRNA methyltransferase BB_0...   175   1e-42
UniRef50_C9A4E5 RNA methyltransferase n=3 Tax=Enterococcus casse...   175   1e-42
UniRef50_A0M5B1 TrmH family tRNA/rRNA methyltransferase n=16 Tax...   175   1e-42
UniRef50_C9M6N6 RNA methyltransferase, TrmH family, group 3 n=1 ...   174   2e-42
UniRef50_B1ZVF9 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Opitu...   174   2e-42
UniRef50_C0WU39 RNA methyltransferase n=3 Tax=Lactobacillus RepI...   174   2e-42
UniRef50_Q7TU91 tRNA/rRNA methyltransferase n=3 Tax=Prochlorococ...   174   2e-42
UniRef50_Q0VMF8 RNA methyltransferase, TrmH family, group 3 n=2 ...   174   2e-42
UniRef50_D1NAJ1 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Victi...   174   3e-42
UniRef50_D1PXH3 SpoU rRNA methylase n=1 Tax=Prevotella bergensis...   174   3e-42
UniRef50_B8D292 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Halot...   174   3e-42
UniRef50_Q8DNE3 Possible rRNA/tRNA methylase n=69 Tax=Streptococ...   173   3e-42
UniRef50_B5CKU5 Putative uncharacterized protein n=1 Tax=Ruminoc...   173   3e-42
UniRef50_A9KHD7 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Clost...   173   4e-42
UniRef50_A5N255 Predicted methyltransferase n=28 Tax=Clostridium...   173   4e-42
UniRef50_A1WUS8 RNA methyltransferase, TrmH family, group 3 n=8 ...   173   4e-42
UniRef50_D0JB44 tRNA/rRNA methyltransferase n=2 Tax=Blattabacter...   173   5e-42
UniRef50_D0LZ96 RNA methyltransferase, TrmH family, group 3 n=1 ...   173   5e-42
UniRef50_D1J7J9 tRNA/rRNA methyltransferase n=2 Tax=Mycoplasma R...   172   5e-42
UniRef50_A8MI79 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Clost...   172   6e-42
UniRef50_UPI0001C42339 RNA methyltransferase, TrmH family n=1 Ta...   172   8e-42
UniRef50_C4V3B4 TrmH family rRNA methyltransferase n=2 Tax=Selen...   172   9e-42
UniRef50_Q7MTU3 RNA methyltransferase, TrmH family n=5 Tax=Bacte...   172   9e-42
UniRef50_C5WEU6 23S rRNA methyltransferase n=2 Tax=Firmicutes Re...   172   9e-42
UniRef50_A5EVE3 RNA methyltransferase, TrmH family, group 3 n=1 ...   170   2e-41
UniRef50_C0X8M7 RNA methyltransferase n=36 Tax=Enterococcus RepI...   170   3e-41
UniRef50_Q8EPH3 rRNA methylase n=1 Tax=Oceanobacillus iheyensis ...   170   3e-41
UniRef50_B0MYM4 Putative uncharacterized protein n=1 Tax=Alistip...   170   3e-41
UniRef50_C0QAQ0 SpoU n=1 Tax=Desulfobacterium autotrophicum HRM2...   170   3e-41
UniRef50_Q1IND6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Candi...   170   4e-41
UniRef50_P94538 Uncharacterized tRNA/rRNA methyltransferase ysgA...   170   4e-41
UniRef50_C0W229 tRNA/rRNA methyltransferase n=2 Tax=Actinomyces ...   169   5e-41
UniRef50_C8NEH0 TrmH family RNA methyltransferase n=2 Tax=Granul...   169   5e-41
UniRef50_C7NJ34 rRNA methylase n=2 Tax=Micrococcineae RepID=C7NJ...   169   5e-41
UniRef50_Q6MA83 Putative rRNA methylase n=2 Tax=Chlamydiae/Verru...   169   5e-41
UniRef50_C5SHP3 RNA methyltransferase, TrmH family, group 3 n=3 ...   169   5e-41
UniRef50_Q2S465 RRNA methylase n=1 Tax=Salinibacter ruber DSM 13...   169   8e-41
UniRef50_B6YR56 23S rRNA (Guanosine-2'-O-)-methyltransferase n=1...   169   9e-41
UniRef50_Q09CR8 RRNA methylase n=2 Tax=Cystobacterineae RepID=Q0...   169   9e-41
UniRef50_D0MG21 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Rhodo...   169   9e-41
UniRef50_C0BGA8 RNA methyltransferase, TrmH family, group 3 n=1 ...   169   1e-40
UniRef50_Q4A651 Putative tRNA/rRNA methyltransferase n=1 Tax=Myc...   168   1e-40
UniRef50_A4XKC2 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Clost...   168   1e-40
UniRef50_D0B4K6 tRNA/rRNA methyltransferase n=41 Tax=Rhizobiales...   168   1e-40
UniRef50_B7GPD2 RNA methyltransferase, TrmH family, group 3 n=4 ...   168   1e-40
UniRef50_B9KYY7 RNA methyltransferase, TrmH family, group 3 n=4 ...   168   1e-40
UniRef50_D1AU26 RNA methyltransferase n=1 Tax=Anaplasma centrale...   168   2e-40
UniRef50_C2KTT3 TrmH family tRNA/rRNA methyltransferase n=2 Tax=...   167   2e-40
UniRef50_A0LPE7 RNA methyltransferase, TrmH family, group 3 n=1 ...   167   2e-40
UniRef50_O30272 Uncharacterized tRNA/rRNA methyltransferase AF_2...   167   2e-40
UniRef50_Q03G93 rRNA methylase n=1 Tax=Pediococcus pentosaceus A...   167   3e-40
UniRef50_A9WLY5 23S rRNA methyltransferase TrmH, group 3 n=11 Ta...   166   4e-40
UniRef50_B0MRI6 Putative uncharacterized protein n=1 Tax=Eubacte...   166   4e-40
UniRef50_D2RCJ3 RNA methyltransferase, TrmH family, group 3 n=14...   166   5e-40
UniRef50_A4S6N6 Predicted protein (Fragment) n=1 Tax=Ostreococcu...   166   5e-40
UniRef50_C7PMX4 RNA methyltransferase, TrmH family, group 3 n=1 ...   166   5e-40
UniRef50_B2GD96 rRNA methylase n=26 Tax=Bacilli RepID=B2GD96_LACF3    166   5e-40
UniRef50_B0PD55 Putative uncharacterized protein n=1 Tax=Anaerot...   166   6e-40
UniRef50_A8S2F6 Putative uncharacterized protein n=8 Tax=Clostri...   166   6e-40
UniRef50_Q11C30 tRNA/rRNA methyltransferase (SpoU) n=21 Tax=Alph...   165   8e-40
UniRef50_A7VXH5 Putative uncharacterized protein n=1 Tax=Clostri...   165   8e-40
UniRef50_Q04SA9 TRNA (Guanosine-2'-O-)-methyltransferase n=4 Tax...   165   8e-40
UniRef50_Q2ST10 RNA methyltransferase, TrmH family, group 3 n=5 ...   165   1e-39
UniRef50_A8DJH5 TsnR n=1 Tax=Candidatus Chloracidobacterium ther...   165   1e-39
UniRef50_C9XLS4 Putative RNA methylase n=9 Tax=Clostridium RepID...   165   1e-39
UniRef50_C1E8J5 Predicted protein (Fragment) n=3 Tax=Mamiellales...   165   1e-39
UniRef50_B5YIM1 RNA methyltransferase, TrmH family n=1 Tax=Therm...   165   1e-39
UniRef50_C7M4Y5 tRNA/rRNA methyltransferase (SpoU) n=13 Tax=Bact...   165   1e-39
UniRef50_B2KBE6 RNA methyltransferase, TrmH family, group 3 n=1 ...   165   1e-39
UniRef50_B9E768 rRNA methyltransferase homolog n=1 Tax=Macrococc...   165   1e-39
UniRef50_B9Y9V6 Putative uncharacterized protein n=1 Tax=Holdema...   164   1e-39
UniRef50_UPI0001BC4585 23S rRNA methyltransferase n=1 Tax=Fusoba...   164   2e-39
UniRef50_B7C827 Putative uncharacterized protein n=1 Tax=Eubacte...   164   2e-39
UniRef50_D2R0C4 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Pirel...   164   2e-39

Sequences not found previously or not previously below threshold:

UniRef50_C8W818 RNA methyltransferase, TrmH family, group 3 n=7 ...   171   1e-41
UniRef50_Q2GL62 RNA methyltransferase, TrmH family, group 3 n=5 ...   170   3e-41
UniRef50_A4E9D9 Putative uncharacterized protein n=1 Tax=Collins...   170   3e-41

>UniRef50_P0AGJ3 tRNA guanosine-2'-O-methyltransferase n=231 Tax=Bacteria
           RepID=TRMH_ECO57
          Length = 229

 Score =  350 bits (900), Expect = 2e-95,   Method: Composition-based stats.
 Identities = 229/229 (100%), Positives = 229/229 (100%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM
Sbjct: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
           ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ
Sbjct: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE
Sbjct: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQAAG 229
           AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQAAG
Sbjct: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQAAG 229


>UniRef50_Q0VRD7 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Alcanivorax
           RepID=Q0VRD7_ALCBS
          Length = 230

 Score =  288 bits (737), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 110/226 (48%), Positives = 154/226 (68%), Gaps = 2/226 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M P RY RIC+ L RRQPDLTV M+ VHKPHN++AI+RT DAVG+ +VHAV P +R R  
Sbjct: 1   MTPERYRRICDTLDRRQPDLTVIMDGVHKPHNIAAIVRTCDAVGILDVHAVLPKNRARMA 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
           A  A GS  WVQV       D +  L+GQG+Q+LA HLSD+A+++R++DYTRPT +L+G 
Sbjct: 61  AGTAMGSQRWVQVHKRDESTDVIRELQGQGVQVLAAHLSDDAIEYRQVDYTRPTALLLGT 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G++ E  +  DQ++ IPM+GMV+S NVSVA+A+IL EA  QR+  G Y  +   +  
Sbjct: 121 EKFGVSDEVASAVDQNVTIPMMGMVESFNVSVAAAIILSEACEQRRAKGFY--DQPRVAA 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQ 226
           A    LLF  GY  +A++    G+PYP ++++G+++  A   A +Q
Sbjct: 179 ARYHELLFRWGYARIARLCDAHGVPYPELDEEGQVKDSAALTALLQ 224


>UniRef50_Q15Z06 tRNA (Guanosine-2'-O-)-methyltransferase n=2 Tax=Pseudoalteromonas
           atlantica T6c RepID=Q15Z06_PSEA6
          Length = 256

 Score =  285 bits (731), Expect = 7e-76,   Method: Composition-based stats.
 Identities = 133/229 (58%), Positives = 175/229 (76%), Gaps = 3/229 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M+  RY RI ++L+ RQP LTVC+EQVHKPHNVSA++R+ DAVG++ +H VW     +  
Sbjct: 7   MSVERYQRIRKLLSTRQPSLTVCLEQVHKPHNVSAVLRSCDAVGINRIHGVWDQK-TKIR 65

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A GS  WV+ + H +IGDAV+ LK Q MQ+L THLSD++VDFR+IDYT+PT I++GQ
Sbjct: 66  KGTAMGSEHWVKTEMHTSIGDAVSVLKQQNMQVLVTHLSDDSVDFRDIDYTQPTAIILGQ 125

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G T+EA+A+AD++I+IPM+GMVQSLNVSVA+A++LYEAQRQR+ AGMY   +  L E
Sbjct: 126 EKHGATEEAIAVADKNIVIPMVGMVQSLNVSVAAAVVLYEAQRQREVAGMY--NSLQLSE 183

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQAAG 229
            E QR+LFEGG+PVL+ V + KGL YPH+++ G I ADA WW  MQ   
Sbjct: 184 EECQRVLFEGGFPVLSNVCRNKGLDYPHIDEGGNIVADASWWQKMQTTA 232


>UniRef50_B5JS83 tRNA (Guanosine-2-O)-methyltransferase n=3 Tax=Bacteria
           RepID=B5JS83_9GAMM
          Length = 225

 Score =  282 bits (723), Expect = 6e-75,   Method: Composition-based stats.
 Identities = 114/213 (53%), Positives = 147/213 (69%), Gaps = 2/213 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M+P R+ R  + L RRQ  LTV ME VHKPHN SAI+R+ +AVGVH  HAV+P   +   
Sbjct: 1   MSPERHQRFIDTLKRRQTSLTVVMENVHKPHNFSAIVRSCEAVGVHRAHAVYPEGGIGNN 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
           A    G++ WVQV THR I      LK QG Q+L  HL + AVDFRE+DYT+PT ++MG 
Sbjct: 61  AGTTVGAHKWVQVDTHRNIQTPFQQLKAQGFQLLTAHLDETAVDFREVDYTQPTAVVMGS 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E  GI++EA  LAD  I+IPM+G+ +SLNVSVA+ALIL+EAQRQRQ AGMY  E   L E
Sbjct: 121 ELHGISEEAAQLADHSIVIPMLGLTESLNVSVATALILFEAQRQRQLAGMY--EQPELDE 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQG 213
           A ++ L+FE  YP LA+  + +G PYP ++ +G
Sbjct: 179 ATRKTLMFEWAYPDLARRYQSRGEPYPELDDEG 211


>UniRef50_C5BJC4 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Gammaproteobacteria
           RepID=C5BJC4_TERTT
          Length = 228

 Score =  277 bits (710), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 98/227 (43%), Positives = 142/227 (62%), Gaps = 2/227 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M P R+ RI  +L +RQPDLTV  ++VHK  N+SAI RT DAVG+  +H V P    +T 
Sbjct: 1   MTPERFQRITSVLNKRQPDLTVITDEVHKGRNLSAITRTCDAVGIDTIHCVMPEDGYQTY 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              +A +  WV V+ H +I   V  LK +G Q++A +L DN +D+R +DYT+PT +++G 
Sbjct: 61  NGTSASAEKWVAVQHHSSISAPVNDLKREGFQLVAANLGDNTLDYRNVDYTKPTALVLGA 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E  G++ EA A  D ++ +PM+GMV+S NVSVA+A+IL EAQ QRQ AG+Y  +   L  
Sbjct: 121 EVKGVSPEAAAAVDYNVTVPMVGMVESFNVSVAAAIILMEAQHQRQQAGLY--DQPRLTA 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQA 227
              +   F   +PVLAK     G+ YP V + GE++  + W++  QA
Sbjct: 179 DVYRARFFHWAHPVLAKWCDDNGVEYPPVREDGEVKNLSAWYSAEQA 225


>UniRef50_A1U493 tRNA guanosine-2'-O-methyltransferase n=3 Tax=Gammaproteobacteria
           RepID=A1U493_MARAV
          Length = 244

 Score =  274 bits (703), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 105/227 (46%), Positives = 139/227 (61%), Gaps = 3/227 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M P R ARI ++L  RQPDL V  +QVHKP N+SAIIR+ DA G+  +H VWP    R  
Sbjct: 1   MTPERLARIKQVLNTRQPDLRVLTDQVHKPRNLSAIIRSCDAFGLANMHVVWPKEGFRAF 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A GS  WV   TH T+ +AV  LK QG ++ A  LSD AVDFRE+DYT P  I+MG 
Sbjct: 61  RKTAGGSFHWVTTHTHPTMDNAVTELKAQGHKLYAAQLSDRAVDFREVDYTVPCTIIMGN 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E  G+       AD+ I+IPM+GMV+SLNVS A ++IL EAQRQR+ AGM+  +   +P+
Sbjct: 121 EVDGVNPVTAEQADEHIVIPMMGMVESLNVSSACSIILSEAQRQRKLAGMF--DQRRMPD 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQ-GEIEADADWWATMQ 226
            E  RLLF    P + +    + LPYP ++ + GE+     W   ++
Sbjct: 179 DEYNRLLFCWCQPTVKRYCDDRNLPYPPIDHETGELIDGVGWMQEVR 225


>UniRef50_C7R944 tRNA guanosine-2'-O-methyltransferase n=1 Tax=Kangiella koreensis
           DSM 16069 RepID=C7R944_KANKD
          Length = 231

 Score =  272 bits (696), Expect = 7e-72,   Method: Composition-based stats.
 Identities = 110/220 (50%), Positives = 151/220 (68%), Gaps = 3/220 (1%)

Query: 2   NPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA 61
           +P R  +I  +L+ RQPDLTV M+QVHKPHN++AI+RTADAVG+  VHAV+P     T  
Sbjct: 5   SPARLQKILTLLSNRQPDLTVFMDQVHKPHNLAAIVRTADAVGIGHVHAVFPEDVKFTGH 64

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
             ++GS  WV    H  +   +A +K +GMQ+LA H SD AVDFR IDYT+PTC+L+G E
Sbjct: 65  HTSSGSKRWVTTHKHSNLKSGIAEMKAKGMQVLAAHFSDTAVDFRTIDYTQPTCLLVGSE 124

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEA 181
             G++ EA  +ADQ +IIPM+GMVQSLNVSVA+ALILYEAQRQR +A MY      +P+A
Sbjct: 125 LVGVSDEAAEIADQHVIIPMVGMVQSLNVSVATALILYEAQRQRSDAEMY--GECKIPQA 182

Query: 182 EQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADW 221
           E   + F+  +P + +   +  + YP +++ G+I  D +W
Sbjct: 183 EVDEICFKALHPTITRFCDKHKIRYPKMDEFGDI-DDPEW 221


>UniRef50_A3IM41 RRNA methylase SpoU n=1 Tax=Cyanothece sp. CCY0110
           RepID=A3IM41_9CHRO
          Length = 220

 Score =  266 bits (682), Expect = 3e-70,   Method: Composition-based stats.
 Identities = 106/215 (49%), Positives = 143/215 (66%), Gaps = 2/215 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           + P RY RI ++L +RQPDLT+  E VHKPHN+SAIIRT DAVG+ +VH +       T 
Sbjct: 3   LLPRRYHRIRQVLEKRQPDLTILTEDVHKPHNLSAIIRTCDAVGILDVHCINTTDEFPTF 62

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
           +  + GS+ WV + +H  I   + HLK Q   I A H +D ++D+REIDYT+PT IL+G 
Sbjct: 63  SQVSQGSDKWVFLHSHPNIKTGINHLKRQNFNIYAAHFTDQSLDYREIDYTQPTAILLGA 122

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G+++EA  L D  II+PM+GMVQSLNVSVA+A+IL+EAQRQR    MY  + S L  
Sbjct: 123 EKWGVSEEAANLVDGHIIVPMLGMVQSLNVSVAAAVILFEAQRQRLAQKMY--DTSRLDL 180

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEI 215
               ++LFE  YP LA + ++KG  YP + + G I
Sbjct: 181 DRYHKILFEWSYPALATIYQKKGENYPSLGKNGVI 215


>UniRef50_Q7TV55 tRNA/rRNA methyltransferase (SpoU) n=34 Tax=cellular organisms
           RepID=Q7TV55_PROMM
          Length = 245

 Score =  266 bits (682), Expect = 3e-70,   Method: Composition-based stats.
 Identities = 100/218 (45%), Positives = 137/218 (62%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           + P R+ R+  +L  R  DLTV +E V KPHN+SAI+R+ DAVGV E HAV    R+ T 
Sbjct: 19  LLPRRFDRLKAVLDCRMADLTVLLEHVEKPHNLSAILRSCDAVGVLEAHAVNYSGRLPTF 78

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
            S A GS  W+ +K H +I  AV  +K  G ++  THL  NA D+R+ D+  PT  ++G 
Sbjct: 79  NSTAQGSQKWIPLKEHSSIEVAVKAIKDSGFRLYGTHLGGNARDYRDCDFCEPTAFVLGA 138

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G+++ A  L D+ I IPM GMVQSLNVSVA+A +L+EA RQR+ AG+  +    L  
Sbjct: 139 EKWGLSKLATPLMDEGIFIPMSGMVQSLNVSVAAATLLFEALRQRRLAGIAPQAGEGLEP 198

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEAD 218
           A  Q+ LFE  YP +A   +++G  YP +N QGEI+  
Sbjct: 199 ALYQQRLFEWAYPEVAAWCQQEGKSYPALNDQGEIQGS 236


>UniRef50_Q1N3Z0 Putative tRNA/rRNA methyltransferase n=1 Tax=Bermanella marisrubri
           RepID=Q1N3Z0_9GAMM
          Length = 229

 Score =  266 bits (682), Expect = 3e-70,   Method: Composition-based stats.
 Identities = 104/221 (47%), Positives = 138/221 (62%), Gaps = 2/221 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M P R  R+ ++L +RQPDLT+  + V KPHN+SAIIR+ DA  V+E++ VWP    +T 
Sbjct: 1   MTPERVQRMHDILRKRQPDLTLITDAVFKPHNLSAIIRSCDAFAVNELNVVWPYDDYQTF 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A GS  +V VKTH+ +  A+   K QG QI+A H  D AV   +IDYT+PT I+MG 
Sbjct: 61  RGRAMGSQQYVNVKTHKDVSQAIQGFKQQGYQIVAAHFCDQAVPHYDIDYTKPTAIVMGA 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G++ +A+ L D  II+PM GMVQSLNVSVA+ALIL EA  QR+N GM     + L  
Sbjct: 121 EKNGVSAKAMDLVDHSIIVPMEGMVQSLNVSVAAALILSEAMHQRKNKGM--LGENQLDS 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADW 221
              Q   FE  YP LAK  K+ G+ YP + + G+    A +
Sbjct: 179 ETYQIQFFEWCYPDLAKRCKKLGMAYPKLKENGDFVEPAAF 219


>UniRef50_Q0AB97 tRNA guanosine-2'-O-methyltransferase n=2
           Tax=Ectothiorhodospiraceae RepID=Q0AB97_ALHEH
          Length = 220

 Score =  260 bits (665), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 105/216 (48%), Positives = 147/216 (68%), Gaps = 2/216 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M   R  R+ + L RRQPDL V ++QVHKPHN+SAI+RT DAVGV   HAV         
Sbjct: 1   MTARRLHRMRQTLERRQPDLQVLLDQVHKPHNLSAILRTCDAVGVPRAHAVSRHQDFTVH 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
            +A++G+  WV V+TH  +  AV  ++GQGM++ A HLS+ AVD+R++DYT+P C+L+G 
Sbjct: 61  RAASSGTGQWVAVETHADLPAAVRAVQGQGMKVYAAHLSEQAVDYRQVDYTKPCCLLLGA 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G+++E  ALAD  +IIPM G+  SLNVSVA+A+IL+EAQRQR  AG Y  E   + E
Sbjct: 121 EKEGVSEEGAALADGHVIIPMFGLGASLNVSVAAAVILFEAQRQRLAAGQY--ETPRMAE 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIE 216
           AE  R L E  +P +A+  +++G PYP +++ G + 
Sbjct: 179 AEITRTLVEWLHPRIAERCRKEGRPYPALDEDGGVI 214


>UniRef50_A4SEW2 tRNA guanosine-2'-O-methyltransferase n=10 Tax=Chlorobiaceae
           RepID=A4SEW2_PROVI
          Length = 232

 Score =  259 bits (663), Expect = 6e-68,   Method: Composition-based stats.
 Identities = 103/216 (47%), Positives = 143/216 (66%), Gaps = 2/216 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           + P R+ RI +MLA RQPDLTV M+ V+KPHN+SAIIR+ DAVG+H+++AV     + T 
Sbjct: 2   IAPERFLRIKKMLASRQPDLTVVMDNVNKPHNLSAIIRSCDAVGIHDLYAVSSKKSIHTT 61

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
            +AAAG+  W  +   + IG     L  +GMQ+LA   ++ + DFR ID+T PT I++G 
Sbjct: 62  QNAAAGAGRWTNLHLRKDIGTLCRKLGMEGMQVLAATNTEESRDFRTIDFTLPTAIVLGA 121

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E  G++ EA+  AD  I IPM GMV+SLNVSVA+ALIL+EA+RQR   GMY      L E
Sbjct: 122 EWEGVSAEAIQAADMAITIPMYGMVESLNVSVAAALILFEAERQRSLKGMY--RTRRLEE 179

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIE 216
           +  ++LLFE  YP L++  + KG  YP +++ G I 
Sbjct: 180 SLYRKLLFELSYPRLSRQLREKGGAYPELDEDGGIV 215


>UniRef50_C1XS02 rRNA methylase n=2 Tax=Bacteria RepID=C1XS02_9DEIN
          Length = 228

 Score =  257 bits (657), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 113/223 (50%), Positives = 149/223 (66%), Gaps = 10/223 (4%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAV--------W 52
           M P R+ +I ++LARRQPDLTV ME+VHK HN SA++R+ DAVGV E H +         
Sbjct: 1   MTPERWQKIQQVLARRQPDLTVLMERVHKWHNFSAVLRSCDAVGVLEAHLIPAAHGIPTE 60

Query: 53  PGSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR 112
             +  R  A+ +  +  WV ++T+     A A L+ +G  I A H S  A+D+RE+DYTR
Sbjct: 61  DQNPSRHTAATSGSAAKWVGLRTYPDTPSAFADLRSRGFVIYAAHFSHKAIDYREVDYTR 120

Query: 113 PTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYL 172
           PTCIL+G EK G+T+EA  LAD  I+IPM+GMVQSLNVSVA+A+IL+EAQRQR  AGMY 
Sbjct: 121 PTCILLGTEKWGVTEEAATLADGHIVIPMMGMVQSLNVSVAAAVILFEAQRQRIQAGMYD 180

Query: 173 RENSMLPEAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEI 215
           R    L  A  QRLLFE  YP  A+  +++G  YP ++ +GEI
Sbjct: 181 R--PRLEPALHQRLLFEWAYPDWAERCRKEGRDYPALSPEGEI 221


>UniRef50_B3QXG6 tRNA guanosine-2'-O-methyltransferase n=1 Tax=Chloroherpeton
           thalassium ATCC 35110 RepID=B3QXG6_CHLT3
          Length = 219

 Score =  253 bits (648), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 102/215 (47%), Positives = 144/215 (66%), Gaps = 2/215 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           ++  R+ +I  +L +RQPDLTV ME V+K HN++AIIRT DAVG+ +VHAV     +RT 
Sbjct: 4   VSSDRFQQIKRLLDKRQPDLTVVMENVNKAHNLAAIIRTCDAVGIPKVHAVALRPEIRTK 63

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
            ++A+G+N WV V+ H +  D  + L+  G QI   H S  A DFR +D+T+PT +++G 
Sbjct: 64  QNSASGANRWVDVQIHNSTEDVFSTLRQGGFQIFVAHFSPQATDFRAVDFTKPTALVVGA 123

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E  GI++ A++LAD  + +PM+GMV+SLNVSVA+A++L+EAQRQR   G Y  +   L E
Sbjct: 124 EWEGISETAISLADGSLYVPMVGMVESLNVSVATAIMLFEAQRQRTEKGFY--DKPRLDE 181

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEI 215
           A  QRLLFE  YP +A   K+K    P +N  GEI
Sbjct: 182 ATYQRLLFELTYPQIATAYKQKDKALPKMNMDGEI 216


>UniRef50_A4BEK2 Putative tRNA methyltransferase n=1 Tax=Reinekea blandensis MED297
           RepID=A4BEK2_9GAMM
          Length = 224

 Score =  229 bits (585), Expect = 6e-59,   Method: Composition-based stats.
 Identities = 85/214 (39%), Positives = 128/214 (59%), Gaps = 6/214 (2%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA 64
           RY +  ++L +RQ D+T+  ++VHK  NVSAI+RTAD+VG+  VH V P          A
Sbjct: 5   RYLKFQQVLNQRQNDMTILTDKVHKSQNVSAIMRTADSVGIPTVHMVKPERGRLVYHHTA 64

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTG 124
            G++ +V V  + T+ + +  L+  GM + A H SD A+ +RE DYTRP  +++G EK G
Sbjct: 65  GGASRFVDVIVYETLSEGIQSLRNAGMALYAAHWSDRAISYREADYTRPFALILGAEKYG 124

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAE-- 182
           I+ EA   AD+ +IIPM+G  +SLNVSVAS +IL EA  QR    M  +  + LP+ +  
Sbjct: 125 ISPEAADAADEHLIIPMVGACESLNVSVASGIILQEAMHQR----MAQQAYTQLPDQDST 180

Query: 183 QQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIE 216
               LF   +P +A     + LPYP +++ G++ 
Sbjct: 181 YHNTLFRWLHPKMAAFCDARQLPYPQLDEDGDMI 214


>UniRef50_O67577 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Bacteria
           RepID=TRMH_AQUAE
          Length = 211

 Score =  228 bits (583), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 86/198 (43%), Positives = 121/198 (61%), Gaps = 3/198 (1%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAV-WPGSRMRTMASA 63
           R  R+ E+L +RQ DL V  + V   HN SAI+RT DAVGV  ++     G + +     
Sbjct: 11  RLKRLREVLEKRQKDLIVFADNVKNEHNFSAIVRTCDAVGVLYLYYYHAEGKKAKINEGI 70

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
             GS+ WV ++        +   K +G QI+AT LS  +V+FRE+DYT+PT +++G E  
Sbjct: 71  TQGSHKWVFIEKVDNPVQKLLEFKNRGFQIVATWLSKESVNFREVDYTKPTVLVVGNELQ 130

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAEQ 183
           G++ E + +AD+ I+IPM GM QSLNVSVA+ +ILYEAQRQR+  GMY R    L E E 
Sbjct: 131 GVSPEIVEIADKKIVIPMYGMAQSLNVSVATGIILYEAQRQREEKGMYSR--PSLSEEEI 188

Query: 184 QRLLFEGGYPVLAKVAKR 201
           Q++L +  Y  + K  KR
Sbjct: 189 QKILKKWAYEDVIKERKR 206


>UniRef50_C7PC85 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Chitinophaga pinensis
           DSM 2588 RepID=C7PC85_CHIPD
          Length = 197

 Score =  226 bits (576), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 69/194 (35%), Positives = 115/194 (59%), Gaps = 4/194 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M P R  R+  +L +RQ  LTV +E V  PHN+SA++RT DAVG+ +V+ +   +  R  
Sbjct: 1   MTPERRERLLSVLNKRQAGLTVVLENVFDPHNISAVLRTCDAVGIQDVYVLNTTTARRKR 60

Query: 61  --ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
               +++ +  W+ V         +A ++ +  +I  THL+ +A    E+D+T    ++ 
Sbjct: 61  WGHKSSSSAAKWLTVHQFSDTATCMAVVREKYDKIYTTHLAADAKSLYELDFTGSVALVF 120

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSML 178
           G E+ G+++E   L D + IIP +G+++SLN+SVA A+ +YEA RQ+  AG Y ++N  L
Sbjct: 121 GNEQEGVSEEIRKLCDGNFIIPQVGIIKSLNISVACAVSIYEAMRQKSIAGHYEQKN--L 178

Query: 179 PEAEQQRLLFEGGY 192
           P+A+   LL E G+
Sbjct: 179 PDAQYNALLEEWGF 192


>UniRef50_B8IYB0 tRNA guanosine-2'-O-methyltransferase n=14 Tax=Desulfovibrionales
           RepID=B8IYB0_DESDA
          Length = 250

 Score =  216 bits (550), Expect = 6e-55,   Method: Composition-based stats.
 Identities = 81/191 (42%), Positives = 113/191 (59%), Gaps = 3/191 (1%)

Query: 2   NPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM- 60
              R AR+ E+LA RQPDLT+ +  +H PHNVSAI R+ DA GV  V+  +  +    + 
Sbjct: 60  TERRKARLLEVLAHRQPDLTLVLANIHDPHNVSAIYRSCDAFGVSRVNLYYTNTPFPALG 119

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              +A +  WV+   H+     +  L+GQ MQ+LAT  S  A   R+ D+TRPT ++MG 
Sbjct: 120 RKTSASARKWVESARHKDSAALMESLRGQNMQVLATSCSPTARPLRDWDFTRPTAVIMGN 179

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E +G+  E L +AD ++ IPM GM+QS NVSVA+A+IL EA RQR+ AGMY      +  
Sbjct: 180 EHSGVEPELLQMADGELYIPMYGMIQSFNVSVAAAIILSEAARQREAAGMY--ATPRMAA 237

Query: 181 AEQQRLLFEGG 191
           A  +  L E  
Sbjct: 238 AALEEKLQEWL 248


>UniRef50_B9L1B3 tRNA guanosine-2'-O-methyltransferase n=3 Tax=Bacteria
           RepID=B9L1B3_THERP
          Length = 217

 Score =  214 bits (547), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 84/210 (40%), Positives = 124/210 (59%), Gaps = 13/210 (6%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           +   R AR+ E+LARRQPDLTV +E VH PHNVSA++R+ DAVG+  VH V+       +
Sbjct: 5   ITERRLARMREVLARRQPDLTVVLENVHDPHNVSAVLRSCDAVGLLRVHLVYTLEEFPEL 64

Query: 61  A-SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSD--NAVDFREIDYTRPTCIL 117
           + + +  +  W+++  H +I      L+ QG  I  T+L D   +VD  ++D T+P  ++
Sbjct: 65  SENVSGSALKWLELVFHPSIEACYRTLRSQGFTIYTTYLGDPARSVDLYDLDLTKPVALV 124

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSM 177
            G E+ G++ EA+A AD + +IPM+GMV+SLN+SVA A+ LYEA RQR+ AG Y R    
Sbjct: 125 FGNEQRGVSDEAVAGADGNFVIPMMGMVRSLNISVACAVSLYEALRQRRLAGHYAR--PK 182

Query: 178 LPEAEQQRLLFEGGYPVLAKVAKRKGLPYP 207
           L   E +  L            +R+G   P
Sbjct: 183 LSPIELEERLQRWL--------EREGRALP 204


>UniRef50_A6LPP3 RNA methyltransferase, TrmH family, group 3 n=35 Tax=Firmicutes
           RepID=A6LPP3_CLOB8
          Length = 300

 Score =  212 bits (540), Expect = 8e-54,   Method: Composition-based stats.
 Identities = 46/171 (26%), Positives = 88/171 (51%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW--PG 54
           + P +Y+ + ++L     R +    V +++V  PHN+ +I+RTA+  GVH +        
Sbjct: 129 VTPYKYSEVSDILDLAEKRGEAPFIVILDEVEDPHNLGSIVRTAELFGVHGIILPKRRSA 188

Query: 55  SRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
           S   T+  ++ G+   V++     +   +  LK +G+ I    +      + ++D+  P 
Sbjct: 189 SVSTTVYKSSVGAIEHVKIAKVTNLNSTIEELKEKGIWIYGADIRAEEYSY-QVDFGGPC 247

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            +++G E  GI++  +   D+ I IPM+G + SLN SVA  +I+YE  + R
Sbjct: 248 AVIIGNEGRGISKLTVEKCDKLIKIPMVGKINSLNASVAGGIIMYEVLKGR 298


>UniRef50_A6Q996 tRNA (Guanosine-2'-O-)-methyltransferase n=2
           Tax=Epsilonproteobacteria RepID=A6Q996_SULNB
          Length = 216

 Score =  209 bits (533), Expect = 6e-53,   Method: Composition-based stats.
 Identities = 85/207 (41%), Positives = 121/207 (58%), Gaps = 7/207 (3%)

Query: 4   TRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASA 63
            R  RI ++L  +QP L V ++ VH   N+SAI+RT DAVGV  ++     +R   +   
Sbjct: 12  ERIDRIDQILCCKQPTLKVMLDDVHSSQNLSAILRTCDAVGVQHLYYTTSDNRDLRIHKT 71

Query: 64  -AAGSNSWVQVKTHRTIGD--AVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              G++ WV+     T      +   + +G Q++ THL + AV FRE+DYT+PT I+MG 
Sbjct: 72  ITQGAHRWVERTRISTEEQRVFLQKKQKEGYQVVVTHLEERAVPFREVDYTKPTIIVMGN 131

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G++ E + LAD  IIIPM GMVQSLNVSVA+ALILYEA+RQ   AG Y  +   L +
Sbjct: 132 EKDGVSSETVELADTVIIIPMQGMVQSLNVSVAAALILYEAERQLAEAGKY--DTPQLSK 189

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYP 207
            E++++     Y     +A+R     P
Sbjct: 190 EEREKIKSGWLY--RDNIARRSKGKIP 214


>UniRef50_A9BJB6 RNA methyltransferase, TrmH family, group 3 n=3 Tax=Thermotogaceae
           RepID=A9BJB6_PETMO
          Length = 240

 Score =  208 bits (530), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 43/166 (25%), Positives = 82/166 (49%), Gaps = 5/166 (3%)

Query: 2   NPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRT 59
           N  +Y  + +++  ++    V ++Q+  PHN  AI+RT+ A GV  +      +      
Sbjct: 74  NDFKYENL-DIIEGKEKLFLVILDQIQDPHNFGAIVRTSVAAGVDAIIIPKDNAVEVTPV 132

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
           +   ++G    + +     + + +  LK + + +    +      + EID+    C++ G
Sbjct: 133 VIKVSSGQIFKIPIIKVTNLSNTIETLKKENVWVYGADVEGK--PYYEIDWQGKICLVFG 190

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            E  GI +      D+ + IPM   V+SLNVSV+S +IL+EA++QR
Sbjct: 191 NEGNGIRKNVKNHCDELVSIPMFNNVESLNVSVSSGIILFEAKKQR 236


>UniRef50_Q4L3J1 Putative trmH family tRNA/rRNA methyltransferase n=10 Tax=Bacilli
           RepID=TRMHL_STAHJ
          Length = 249

 Score =  207 bits (529), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 55/176 (31%), Positives = 88/176 (50%), Gaps = 7/176 (3%)

Query: 1   MNPTRYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P  YA   + +  ++        V ++ +  PHN+ +I+RTADA GV  V      S 
Sbjct: 73  IAPYEYADFDQFIQSQKDKEGLSTVVILDGLEDPHNLGSILRTADASGVDGVIIPKRRSV 132

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
              +T+A A+ G+   V V     +   +  LK  G  +     +DNA D+R++    P 
Sbjct: 133 ALTQTVAKASTGAIQHVPVMRVTNLAKTIDELKEHGYWVAGAE-ADNATDYRDMAADMPL 191

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGM 170
            I++G E  G+++      D  I IPM+G V SLN SVA++L++YE  R+R   G 
Sbjct: 192 AIVIGSEGQGMSRLVKDKCDFYIKIPMVGHVNSLNASVAASLMMYEVYRKRHQVGD 247


>UniRef50_B0K5F8 RNA methyltransferase, TrmH family, group 3 n=51 Tax=Firmicutes
           RepID=B0K5F8_THEPX
          Length = 247

 Score =  207 bits (529), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 44/169 (26%), Positives = 91/169 (53%), Gaps = 7/169 (4%)

Query: 4   TRYARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--M 57
            +Y  + ++L     +++    + ++++  PHN+ AIIR+A+A GVH +      +    
Sbjct: 77  YKYFEVDDLLEYAEQKKEKPFLLILDEITDPHNLGAIIRSAEAFGVHGIIIPKRRAVGVN 136

Query: 58  RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
            T+   +AG+   +++     I + +  LK +G+ I+ T ++     F E++Y  P   +
Sbjct: 137 ATVVKTSAGAVEHMRIAKVSNINNTIRDLKERGLWIVGTDVNAE-KSFEELNYDFPVAFV 195

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           +G E  G+++  L   D  + IPM G + SLN SVA+++++Y+   +R+
Sbjct: 196 IGNEGKGVSKLVLQNCDFVVKIPMKGKINSLNASVAASILIYQVVSKRK 244


>UniRef50_C9LMK8 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Dialister
           invisus DSM 15470 RepID=C9LMK8_9FIRM
          Length = 282

 Score =  207 bits (528), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 53/170 (31%), Positives = 81/170 (47%), Gaps = 6/170 (3%)

Query: 1   MNPTRYARICEMLA--RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW--PGSR 56
           + P  YA + E+L+   R+  L + ++ V    N+ AI+RTA+  G   V          
Sbjct: 115 LKPYAYADLEEVLSSCERKDPLLILLDGVEDVRNIGAIVRTAECAGAAAVLLPKHRSSPV 174

Query: 57  MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
                  A+G+ +++ V     I   +  LK +G   +   +     D  + D   P  I
Sbjct: 175 TAAAMKTASGAFAYLPVCQIGNIRQTLEKLKERGFWAVGADMDGG--DLYQADLKGPLVI 232

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           +MG E  GI+     + D  + IPM G V SLNVSVA+AL++YEA RQR 
Sbjct: 233 VMGAEGKGISPLTKRMCDFCVRIPMRGKVSSLNVSVAAALLMYEAVRQRN 282


>UniRef50_C9RX94 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Geobacillus
           RepID=C9RX94_GEOSY
          Length = 247

 Score =  206 bits (525), Expect = 5e-52,   Method: Composition-based stats.
 Identities = 73/206 (35%), Positives = 115/206 (55%), Gaps = 9/206 (4%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMAS 62
           P R  R+ E+L  R   +TV +E V  PHN +A++RTA+A GV +VH V   +       
Sbjct: 32  PRRLRRMYEVLNERTRYITVLIEAVDDPHNQAAVLRTAEAFGVQDVHIVTGKAPFSPNRL 91

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
               ++ W+ +     I  A+A LK QG Q+ A++L +  +   +ID ++PT +L G E 
Sbjct: 92  VTRYADQWLTLHHKPDIKTAIADLKSQGYQVYASYLGEGTIPVSDIDLSQPTALLFGNEH 151

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ-RQRQNAGMYLRENSMLPEA 181
           +G+++EAL LAD   +IPM G VQS N+SVA+AL LY+   R R+ AG     +  L   
Sbjct: 152 SGVSEEALRLADGTFVIPMYGFVQSFNISVAAALALYDVTERARRQAG----RHYYLLPG 207

Query: 182 EQQRLLFEGGY----PVLAKVAKRKG 203
           E++ L  +  +    P + K  +++G
Sbjct: 208 EKKALYEQWMWQTLNPRIRKQLQQQG 233


>UniRef50_Q2JI19 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Synechococcus
           RepID=Q2JI19_SYNJB
          Length = 378

 Score =  206 bits (524), Expect = 6e-52,   Method: Composition-based stats.
 Identities = 54/181 (29%), Positives = 86/181 (47%), Gaps = 11/181 (6%)

Query: 2   NPTRYARICEMLARRQ----PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM 57
            P +Y  + +++ R +      + V ++ +  PHN+ AI R+ +A G+     V P  R 
Sbjct: 178 TPYQYVALEDLVERSRQAGPNPVLVVLDGIQDPHNLGAIARSVEAFGMQG--MVIPQRRA 235

Query: 58  R----TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
                T+   AAG+ S + V     +  A+ +LK QG  +  T  S  A      D+ RP
Sbjct: 236 AGVTSTVMKVAAGALSTLPVARVVNLNRALEYLKEQGFWVYGTT-SRGADPIYSADFQRP 294

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLR 173
             +++G E  GI+       DQ + IP+ G  +SLN SVA+ + LYE  RQR    +   
Sbjct: 295 IALVVGSEGEGISLLTQRHCDQLLSIPLAGRTESLNASVAAGIALYEIHRQRSPHHLKRP 354

Query: 174 E 174
           E
Sbjct: 355 E 355


>UniRef50_Q5HIE3 Putative trmH family tRNA/rRNA methyltransferase n=86
           Tax=Firmicutes RepID=TRMHL_STAAC
          Length = 248

 Score =  205 bits (523), Expect = 8e-52,   Method: Composition-based stats.
 Identities = 54/175 (30%), Positives = 89/175 (50%), Gaps = 7/175 (4%)

Query: 1   MNPTRYARICEMLARRQPD----LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P  YA   + L +++        + ++ +  PHN+ +I+RTADA GV  V      S 
Sbjct: 73  IAPYEYADFDQFLKQQKEKEGLLTVLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSV 132

Query: 57  M--RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
              +T+A A+ G+   V V     +   +  LK  G  +  T  + NA D+R ++     
Sbjct: 133 TLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEAN-NATDYRNLEADMSL 191

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
            I++G E  G+++      D  I IPM+G V SLN SVA++L++YE  R+R + G
Sbjct: 192 AIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFRKRHDVG 246


>UniRef50_Q9JZR3 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=27
           Tax=Neisseria RepID=RLMB_NEIMB
          Length = 250

 Score =  205 bits (523), Expect = 8e-52,   Method: Composition-based stats.
 Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 4/160 (2%)

Query: 9   ICEMLAR-RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAA 65
           + ++L    +P L + ++ +  PHN+ A +RTADA+GVH V A    S     T++  A 
Sbjct: 85  LEDVLENLSEPPLLLILDGITDPHNLGACLRTADAMGVHAVIAPKDKSAGLNATVSKVAC 144

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G+   V   T   +   +  LK  G+ I+ T +S  + D    +       +MG E  G+
Sbjct: 145 GAAETVPYITVTNLARTLRELKEYGIWIIGTDMSGES-DLYHCNLPDSAAWVMGNEGDGM 203

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            +      D  + IPM G V+S+NVSV++ ++L E +RQR
Sbjct: 204 RRLTREHCDMLVSIPMFGTVESMNVSVSAGMVLSETRRQR 243


>UniRef50_Q1J4P0 23S rRNA Gm2251 methyltransferase n=42 Tax=Lactobacillales
           RepID=Q1J4P0_STRPF
          Length = 257

 Score =  205 bits (523), Expect = 9e-52,   Method: Composition-based stats.
 Identities = 46/165 (27%), Positives = 77/165 (46%), Gaps = 4/165 (2%)

Query: 4   TRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMA 61
           T    I E+  +    L + ++ +  PHN+ +I+RTADA  V  V      S      ++
Sbjct: 95  TDVDEILEIAEQEANPLILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVS 154

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
             + G+   + +     +   +  LK +G  I  T ++    D    +      +++G E
Sbjct: 155 KTSTGAVEHIPIARVTNLSQTLDKLKARGFWIFGTDMNGTPSDCWNTN--GKLALVIGNE 212

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
             GI+       D+ I IPM G VQSLN SVA+A+++YE  R R+
Sbjct: 213 GKGISTNIKKQVDEMITIPMNGHVQSLNASVAAAILMYEVFRNRR 257


>UniRef50_C8P2I4 23S rRNA (Guanosine-2'-O-)-methyltransferase RlmB n=1
           Tax=Erysipelothrix rhusiopathiae ATCC 19414
           RepID=C8P2I4_ERYRH
          Length = 236

 Score =  205 bits (523), Expect = 9e-52,   Method: Composition-based stats.
 Identities = 54/168 (32%), Positives = 90/168 (53%), Gaps = 2/168 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MR 58
           +   +Y  + E++   + +L V  +Q+  PHN+ AI+RT DA GV  V      S     
Sbjct: 69  IQDYKYHSLQEIIKGAKNNLIVLCDQLEDPHNLGAILRTCDACGVDGVVVGKHRSVGLTS 128

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
           T+A  + G+ + V+V     +  A+A LK  G  ++A   + +AVD+ E +   P  +++
Sbjct: 129 TVAKVSTGAINTVKVAEATNMVKAIAELKEAGYWVVAAENAVDAVDYTEFNVDMPLVLVV 188

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           G E  GI++      D    IPM G V SLNVSVA+ ++L++  R+R+
Sbjct: 189 GSEGKGISRLVKKECDILTTIPMQGSVNSLNVSVATGVLLFDIVRRRK 236


>UniRef50_Q0AUG1 Conserved hypothetical tRNA/rRNA methyltransferase yacO n=1
           Tax=Syntrophomonas wolfei subsp. wolfei str. Goettingen
           RepID=Q0AUG1_SYNWW
          Length = 248

 Score =  205 bits (522), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 8/171 (4%)

Query: 4   TRYARICEMLAR-----RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS--R 56
             YA + ++L +      +P   + ++ +  P N+ AIIRTA+  GV  +      S   
Sbjct: 75  YPYADLGQVLEKLQAQKEKPPFLLLLDGIEDPQNLGAIIRTAECAGVDGIIIPSHKSAEV 134

Query: 57  MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
             T++  +AG+   + +     + + + +LK +G  +L          +       PT +
Sbjct: 135 NPTVSRVSAGAVEHMAIIRENNLVNTIKYLKQEGFWVLGADAKAR-QSYFNTSIPSPTAL 193

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           ++G E  GI +      D  + IPM G + SLN SVA+AL++YE  RQR N
Sbjct: 194 VIGGEGQGIRRLVRENCDILVRIPMFGQLNSLNASVAAALLIYEVLRQRLN 244


>UniRef50_C2HJX9 tRNA/rRNA methyltransferase n=3 Tax=Clostridiales Family XI.
           Incertae Sedis RepID=C2HJX9_PEPMA
          Length = 244

 Score =  205 bits (522), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 45/171 (26%), Positives = 82/171 (47%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARICEML--ARR--QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW--PG 54
           M    Y+ + EM+  A++  +    + ++++  PHN+ +IIRTA+  G H V        
Sbjct: 72  MPSFGYSSVDEMIIYAKKINEDPFLIILDEITDPHNLGSIIRTAEVAGCHGVIIPKHRAC 131

Query: 55  SRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T    +AG+   +++     I   + +LK   + I      + +    + +   P 
Sbjct: 132 EVNATAIKTSAGAVFNIKIARVTNITTTINYLKEHNIWIYGA-CGEASQTHTQANLKGPI 190

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            +++G E  GI++      DQ I IPM G  +SLN S A+++++YE  RQR
Sbjct: 191 GLVIGNEGKGISRLVRENCDQLIKIPMYGKTESLNASNAASILIYEIIRQR 241


>UniRef50_C4L0U6 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Bacillales
           RepID=C4L0U6_EXISA
          Length = 254

 Score =  205 bits (522), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 74/208 (35%), Positives = 119/208 (57%), Gaps = 7/208 (3%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           + P R  R+ E+L  R   +T+  E V  PHN SA++R+ADA GV  +H V   ++ +  
Sbjct: 39  LMPDRIKRMYEVLNTRTNHITILTEGVDDPHNQSAVLRSADAFGVQTLHVVEGRAKFKPN 98

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
           +  A  ++ WV V  H +I +A+  LK  G Q+ AT LS+ A+   E+D ++PT +L G 
Sbjct: 99  SIIAKSADRWVDVVEHGSIEEAIDALKESGYQVYATALSEEAIPLEEVDVSKPTVLLFGN 158

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E +G+++ AL  AD + +IPM G VQSLN+SVA+A+ LY+   + ++    + +   LP 
Sbjct: 159 EHSGVSETALHKADGNFVIPMQGYVQSLNISVAAAISLYDVTTRSRH---IVTDGYELPV 215

Query: 181 AEQQRLLFEGGYPVLAKV----AKRKGL 204
            +Q R+  +     L K      K+KG+
Sbjct: 216 EDQARIFKDWMVKSLPKRTLGLYKQKGV 243


>UniRef50_Q7MH13 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=32
           Tax=Proteobacteria RepID=RLMB_VIBVY
          Length = 247

 Score =  204 bits (520), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 54/160 (33%), Positives = 79/160 (49%), Gaps = 3/160 (1%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAA 65
            + ++LA+    L + ++ V  PHN+ A +R ADA GV  V      S     T++  A 
Sbjct: 85  DLDDILAKHASPLLLILDGVTDPHNLGACLRNADAAGVAAVIVPKDKSAPMTATVSKVAC 144

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G+   V +     +   + HL+ QG+ I+ T   +   D  +   T    I+MG E  G+
Sbjct: 145 GAAETVPLVRVTNLARTMRHLQEQGIWIVGTA-GEATHDIYQAKLTGSLAIVMGAEGDGM 203

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            +      D  I IPM G V SLNVSVAS + L+EA RQR
Sbjct: 204 RRLTRETCDDLIKIPMAGAVSSLNVSVASGICLFEAVRQR 243


>UniRef50_Q5HRM1 Putative trmH family tRNA/rRNA methyltransferase n=7
           Tax=Staphylococcaceae RepID=TRMHL_STAEQ
          Length = 249

 Score =  204 bits (520), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 55/173 (31%), Positives = 87/173 (50%), Gaps = 7/173 (4%)

Query: 1   MNPTRYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P  YA   E L +++        + ++ +  PHN+ +I+RTADA GV  V      S 
Sbjct: 73  VAPYEYANFDEFLQKQKKKARYSTVIILDGLEDPHNLGSILRTADASGVDAVIIPKRRSV 132

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
              +T+A A+ G+   V V     +   +  LK  G  I  T  + NA D+R++      
Sbjct: 133 ALTQTVAKASTGAIQHVPVIRVTNLSKTIDELKDNGFWIAGTEAN-NATDYRDLQADMSL 191

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
            I++G E  G+++      D  I IPM+G V SLN SVA++L++YE  R+R  
Sbjct: 192 GIVIGSEGQGMSRLVSDKCDFHIKIPMVGHVNSLNASVAASLMMYEVYRKRHQ 244


>UniRef50_B2A4B9 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Natranaerobius
           thermophilus JW/NM-WN-LF RepID=B2A4B9_NATTJ
          Length = 247

 Score =  204 bits (519), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 56/172 (32%), Positives = 89/172 (51%), Gaps = 8/172 (4%)

Query: 3   PTRYARICEML-----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           P +Y+++  +L       ++P   + ++ +  P N  AIIRTADAVGV  V      S  
Sbjct: 77  PFKYSQLDTVLKGFDYNNQKPLTLLILDHLTDPQNFGAIIRTADAVGVDGVIIPKRRSVD 136

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T+  A++G+   V +     +   ++ LK Q + IL T +  +   F E +Y  P  
Sbjct: 137 VNPTVMKASSGAAEHVPIIKVSNLRQTISKLKEQWIWILGTDIDGDRGIFEE-NYNIPLA 195

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           +++G E +G++       D    IPMIG V SLN SVA+A++LYE  RQ+ N
Sbjct: 196 LVVGNEASGMSPLVKKECDFIANIPMIGRVNSLNASVATAVVLYEIYRQKTN 247


>UniRef50_C3RMB5 23S rRNA methyltransferase n=5 Tax=Bacteria RepID=C3RMB5_9MOLU
          Length = 244

 Score =  203 bits (518), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 53/171 (30%), Positives = 89/171 (52%), Gaps = 6/171 (3%)

Query: 1   MNPTRYARICEMLA---RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           +   RY  I E++      +  L + ++ +  PHN+ AI+RT DA+GV  V      S  
Sbjct: 73  IEEYRYYSIDEIINTIPDGKQPLLLMLDGLEDPHNLGAILRTCDAIGVDGVIIGKNRSVG 132

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T+A  + G+   V+V     +   +  LK +   ++   L D + D+R++DY  P  
Sbjct: 133 LNGTVAKVSTGAIDHVKVAQVTNLTRTLEDLKKRSFWVVGCDL-DKSQDYRQVDYNMPLV 191

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           I++G E  GI++      D ++++PM+G V SLN SVA+A+ILY+    R 
Sbjct: 192 IVIGSEGFGISRLVKKSCDINVVLPMVGHVNSLNASVATAVILYQVYNSRN 242


>UniRef50_P74328 Uncharacterized tRNA/rRNA methyltransferase slr0955 n=1
           Tax=Synechocystis sp. PCC 6803 RepID=Y955_SYNY3
          Length = 384

 Score =  203 bits (518), Expect = 4e-51,   Method: Composition-based stats.
 Identities = 50/173 (28%), Positives = 80/173 (46%), Gaps = 11/173 (6%)

Query: 1   MNPTRYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P  Y  + +++ + +      + + ++ +  PHN+ AIIRTA+A G      V P  R
Sbjct: 195 VAPYHYWELGDLIDKAKSQSTAPVLIIIDSITDPHNLGAIIRTAEAFGAQG--MVLPQRR 252

Query: 57  MR----TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR 112
           +     T+   AAG+     V     +  A+  LK  G  I  T ++       + D   
Sbjct: 253 VAGITSTVMKVAAGALEHFPVARVVNLSRALETLKESGFWIYGT-VAGKQTALHQADLRE 311

Query: 113 PTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           P  +++G E  G++       D  I IP+ G   SLN SVA+A+ LYE  RQR
Sbjct: 312 PMGLVIGSEGEGLSLLTQKHCDHLITIPLAGKTPSLNASVAAAISLYEIFRQR 364


>UniRef50_B3QM30 RNA methyltransferase, TrmH family, group 3 n=12 Tax=Chlorobiaceae
           RepID=B3QM30_CHLP8
          Length = 257

 Score =  203 bits (517), Expect = 4e-51,   Method: Composition-based stats.
 Identities = 60/169 (35%), Positives = 93/169 (55%), Gaps = 5/169 (2%)

Query: 1   MNPTRYARICEMLA--RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM- 57
           +    +  + E+LA  R    L V ++ +  PHNV AIIRTA+AV    V  +       
Sbjct: 88  LTSVTFYTLDEVLAAPRNSSPLLVILQGLEDPHNVGAIIRTAEAVAADSVIMIEGKGAPI 147

Query: 58  -RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
             T+  A+AG+ S ++V   +++   +  L  +G  I+A  + +   +  +ID+ RPT +
Sbjct: 148 SATVHKASAGALSHMRVCKVKSLVKTLDLLHERGFSIVAADM-EAEHNHTDIDWKRPTVL 206

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +MG E  G+  E     DQ + IPM G V+SLNVSVA+ ++LYEA RQR
Sbjct: 207 VMGAEGKGLGSETRKRCDQIVRIPMAGCVESLNVSVAAGVMLYEAMRQR 255


>UniRef50_Q73MR5 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Treponema
           denticola RepID=Q73MR5_TREDE
          Length = 258

 Score =  202 bits (515), Expect = 8e-51,   Method: Composition-based stats.
 Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 4/163 (2%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASA 63
                  LA +     V ++ V  PHN  +IIR+AD  G+  +      S      ++  
Sbjct: 97  VDEFFAKLAEKGSAFVVILDSVTDPHNTGSIIRSADQFGIDGIIVPENKSAGGFEIISKV 156

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           +AG+ +WV       +   V  LK +G  I        A+    + + + T ++MG E  
Sbjct: 157 SAGALAWVPFVEVTNLVRTVERLKKEGFWIYGADAGGKALP--NLTFPKKTVLIMGNEGR 214

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           G+++      D+ + IP  G + SLNVSVA+ ++LYE  R+++
Sbjct: 215 GMSRLVEETCDEIVSIPTKGKLDSLNVSVAAGILLYEISRKKE 257


>UniRef50_Q1G8Z2 TRNA/rRNA methyltransferase n=109 Tax=Bacilli RepID=Q1G8Z2_LACDA
          Length = 255

 Score =  202 bits (515), Expect = 8e-51,   Method: Composition-based stats.
 Identities = 51/166 (30%), Positives = 85/166 (51%), Gaps = 8/166 (4%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTM 60
            + ++ + L + +  L + ++ +  PHN+ +I+R+ADA GV  V  + P  R       +
Sbjct: 92  DFDQLLDKLDQEEAPLLLMLDNIEDPHNLGSILRSADATGVSGV--IIPKRRASGLTSVV 149

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
           A  + G+   V V     +      LK +G  I  T +  +  D+R+ +    T +++G 
Sbjct: 150 AKTSTGAIDHVPVARVNNLVQTCQALKDRGYWIFGTAMEGD--DYRKWNANGKTVLVIGN 207

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           E  GI+   L   DQ + IPMIG VQSLN SVA+ ++LY+A   R 
Sbjct: 208 EGKGISPLLLKQMDQTLTIPMIGHVQSLNASVATGVLLYQAFNSRH 253


>UniRef50_A3DH38 RNA methyltransferase, TrmH family, group 3 n=14 Tax=Firmicutes
           RepID=A3DH38_CLOTH
          Length = 277

 Score =  201 bits (513), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 52/171 (30%), Positives = 87/171 (50%), Gaps = 11/171 (6%)

Query: 5   RYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--- 57
            Y  + ++L     + +    + ++ +   +N+ +I+RTADAVG H V  V P  R    
Sbjct: 110 DYVEVDDILKIAQDKGEDPYIIILDGITDAYNLGSILRTADAVGAHGV--VIPKRRAIGL 167

Query: 58  -RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
              ++ A+AG+  +V V     I   + +LK + + I+ T LS     F E D   P  +
Sbjct: 168 NAAVSKASAGAIEYVPVARVTNISQTIEYLKKKNIWIVGTDLSGE-KPFFEADLKGPVAL 226

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           ++G E  G+ +      D  + IPM G + SLN +VA+A+I+YE +RQR  
Sbjct: 227 VIGSEGEGMGRLVSEKCDFIVNIPMQGKISSLNAAVAAAIIMYEIRRQRNF 277


>UniRef50_B0TC37 RNA methyltransferase, trmh family n=1 Tax=Heliobacterium
           modesticaldum Ice1 RepID=B0TC37_HELMI
          Length = 256

 Score =  201 bits (513), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 53/170 (31%), Positives = 86/170 (50%), Gaps = 7/170 (4%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW--PG 54
           + P  Y  + E+L    A+ +P   + ++ +  PHN+ A++RTA+  G H V       G
Sbjct: 79  VAPVAYVEVEEILEKAKAKGEPPFVLLLDGLEDPHNIGALLRTAEGAGAHGVIIPKRRGG 138

Query: 55  SRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
           +   T+A A+AG+  +V +     +   V  LK  G+ I+ + + D    +   D+  P 
Sbjct: 139 AITSTVAKASAGAVEYVPIARVTNLVQTVGQLKKAGLWIIGSAM-DAPRPYFRQDFRGPV 197

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            +++G E  GI+       D  + IPM G V SLN SVA AL++YE  RQ
Sbjct: 198 GLIVGSEGKGISPLLREHCDHLVSIPMGGKVDSLNASVAGALLMYERVRQ 247


>UniRef50_A2U211 SpoU rRNA methylase family protein n=1 Tax=Polaribacter sp. MED152
           RepID=A2U211_9FLAO
          Length = 229

 Score =  201 bits (513), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 60/216 (27%), Positives = 103/216 (47%), Gaps = 8/216 (3%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           +   R     ++LA R    TV +E +++PHN SA++RT D  GV ++H +      R  
Sbjct: 18  LTDKRKQTFQKVLAERTRHFTVVLEDIYQPHNASAVVRTCDIFGVQDLHVIENRYINRVS 77

Query: 61  ASAAAGSNSWVQVKTHR----TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
                G+  W+  K ++         + HLK  G QI+AT    +A   ++    + T  
Sbjct: 78  KYVTKGAQKWITTKRYKTDGDNTKTCLNHLKTAGYQIIATSPHADANLLQDFKIDKKTAF 137

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENS 176
           + G E TGI+      AD  + IPM+G  +S N+SVA+A+IL +   + +N+    R + 
Sbjct: 138 VFGAEATGISDTVKEHADGFLKIPMVGFTESFNISVAAAIILQDVTTRLKNS----RIDW 193

Query: 177 MLPEAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQ 212
           ML   E+++L  +     +  V K +   Y  +  +
Sbjct: 194 MLSNDEKEQLYLQWIKETIKNVTKIEERFYQQLEDE 229


>UniRef50_B2IX93 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Nostoc
           punctiforme PCC 73102 RepID=B2IX93_NOSP7
          Length = 363

 Score =  201 bits (513), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 51/177 (28%), Positives = 81/177 (45%), Gaps = 10/177 (5%)

Query: 3   PTRYARICEMLARRQP---DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--- 56
           P  Y  + +++ + +     + V  + +  PHN+ AIIRTA+A+G   +  V P  R   
Sbjct: 180 PYGYIELADLIEQSKSVTDPVIVVADGITDPHNLGAIIRTAEAIGAQGL--VIPQRRASG 237

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T+   AAG+     V     +  A+  LK  G  I  T  S  +     +++  P  
Sbjct: 238 ITSTVMKVAAGALENFTVSRVVNLSRALEELKEAGFWIYGTAAS-GSEPVHTVNFKGPIV 296

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYL 172
           +++G E  G+        D  + IP+ G   SLN SVA+ + LYE  RQR    +YL
Sbjct: 297 LVIGSEGEGLGMLTQRSCDFLVSIPLQGKTPSLNASVAAGMALYEIYRQRSLNTLYL 353


>UniRef50_Q606P1 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Methylococcus
           capsulatus RepID=Q606P1_METCA
          Length = 250

 Score =  201 bits (512), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 47/161 (29%), Positives = 76/161 (47%), Gaps = 3/161 (1%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAG 66
           +  + A     L + ++ V  PHN+ A +RT DA GV  +      S     T+A  A+G
Sbjct: 88  LDTLDAADGHPLYLVLDHVQDPHNLGACLRTCDAAGVKGLVVTKDQSVGLTPTVAKVASG 147

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           +   V V     +   +   K +G  ++     +      E+D   P  ++MG E  G+ 
Sbjct: 148 AAETVPVYRVTNLARCLDRFKQRGYWVVGAA-GEAERTLYELDLRLPLVVVMGAEGVGLR 206

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           +      D  + IPM+G V+SLN+SVA+ ++LYE  RQR  
Sbjct: 207 RLTRERCDFLLRIPMVGGVESLNLSVATGIVLYEVMRQRSR 247


>UniRef50_Q06753 Putative trmH family tRNA/rRNA methyltransferase yacO n=86
           Tax=Bacteria RepID=YACO_BACSU
          Length = 249

 Score =  200 bits (510), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 52/174 (29%), Positives = 88/174 (50%), Gaps = 11/174 (6%)

Query: 4   TRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--- 56
             YA + ++      + +    + ++++  PHN+ +I+RTADAVG H +  V P  R   
Sbjct: 78  YEYAELDDLYKAAEEKNEQPFFLILDELEDPHNLGSIMRTADAVGAHGI--VIPKRRAVG 135

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T+A A+ G+   + V     +   +  +K +G+ ++ T  S    DFR +D   P  
Sbjct: 136 LTTTVAKASTGAIEHIPVARVTNLARTLEEMKERGIWVVGTDASARE-DFRNMDGNMPLA 194

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
           +++G E  G+ +      D  I +PM G V SLN SVA+ L++YE  R+R   G
Sbjct: 195 LVIGSEGKGMGRLVKEKCDFLIKLPMAGKVTSLNASVAAGLLMYEVYRKRNPVG 248


>UniRef50_Q88DE7 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=285
           Tax=Proteobacteria RepID=RLMB_PSEPK
          Length = 248

 Score =  200 bits (509), Expect = 3e-50,   Method: Composition-based stats.
 Identities = 47/153 (30%), Positives = 75/153 (49%), Gaps = 3/153 (1%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQV 73
             P L + ++ V  PHN+ A +RTADA G   V      S   T  +   A G+   + +
Sbjct: 94  ETPPLILVLDGVTDPHNLGACLRTADAAGATAVIVPKDKSATLTPVVRKVACGAAEVIPL 153

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALA 133
                +   +  L+ +G+ ++ T   +   +  + D T P  ++MG E  G+ +      
Sbjct: 154 VAVTNLARTLEKLQQRGLWVVGTA-GEAEQEIYQQDLTGPLVMIMGAEGKGMRRLTREHC 212

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           D  + +PM G V SLNVSVA+ + L+EA RQRQ
Sbjct: 213 DFLVKLPMAGSVSSLNVSVATGVCLFEAVRQRQ 245


>UniRef50_B0P8C0 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0P8C0_9FIRM
          Length = 256

 Score =  200 bits (509), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 50/154 (32%), Positives = 78/154 (50%), Gaps = 4/154 (2%)

Query: 14  ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSNSWV 71
           AR +P L V  + +  PHN+ AIIRTA+A G H +     G       +   +AG+   +
Sbjct: 102 ARGEPPLLVIADSIEDPHNLGAIIRTAEAAGAHGLIIPKRGGAGLTAIVGRTSAGAVEHL 161

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            V     +   +  LK +G+ I     S    D  + D T P+ +++G E  G+++    
Sbjct: 162 PVARVTNLVSTIKELKARGVWIYGADASGARWD--QTDLTGPSALVIGSEGFGLSRLVRE 219

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             D  + +PM G V SLN SVA+ +++YEA RQR
Sbjct: 220 TCDALLSLPMRGEVNSLNASVAAGILMYEAVRQR 253


>UniRef50_B2UR21 RNA methyltransferase, TrmH family, group 3 n=3
           Tax=Chlamydiae/Verrucomicrobia group RepID=B2UR21_AKKM8
          Length = 193

 Score =  200 bits (509), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 49/159 (30%), Positives = 74/159 (46%), Gaps = 3/159 (1%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAG 66
           +  +L +    L + ++ V  PHN+ AI+RTAD  GV  V A    S     T+   + G
Sbjct: 35  LDGILDKSSNPLLLILDCVQDPHNLGAILRTADGAGVDAVIAPRDKSVGITETVLRVSVG 94

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           +   V       +   +  L+ +G+ I  T          E D+T P  ++MG E  G+ 
Sbjct: 95  AAEKVPFIQVTNLARTMKQLQSRGIWIFGTS-DKGDRGLYETDFTGPAALVMGAEGEGMR 153

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +      D  + IPM G +  LNVSVA+ + LYE  RQR
Sbjct: 154 RLTEENCDFLLRIPMKGSIPCLNVSVATGVCLYEMVRQR 192


>UniRef50_C5CF29 RNA methyltransferase, TrmH family, group 3 n=7 Tax=Thermotogaceae
           RepID=C5CF29_KOSOT
          Length = 250

 Score =  200 bits (509), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 38/169 (22%), Positives = 74/169 (43%), Gaps = 7/169 (4%)

Query: 1   MNPTRYARICEMLAR---RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           +    Y  +  +L +   ++  L V ++++  PHN+ AIIR++ A G   V      S  
Sbjct: 75  LKEFPYTSLETLLDKIMEKKRSLLVLLDRIQDPHNLGAIIRSSVAAGADGVIITEKASVE 134

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
               +   + G    + +     +   +  LK +G    A  +      +  + +T    
Sbjct: 135 VTPAVVKVSTGLVFRIPIVRVVNMARTIETLKEEGFWTYAATMEGE--PYYSVSFTDKAA 192

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           ++ G E  GI       +D  + IPM   + SLNV+ ++A++L+E +RQ
Sbjct: 193 LIFGNEGKGIRHLVKKKSDYLVSIPMCEGIDSLNVAASAAIMLFEYRRQ 241


>UniRef50_Q1D7V2 RNA methyltransferase, TrmH family, group 3 n=7 Tax=Bacteria
           RepID=Q1D7V2_MYXXD
          Length = 282

 Score =  199 bits (508), Expect = 5e-50,   Method: Composition-based stats.
 Identities = 55/171 (32%), Positives = 85/171 (49%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           +   +YA + ++L    A  QP L V ++ +  PHN+ AIIR+ADA+G H V      + 
Sbjct: 107 LRGFKYAELEDLLEAAKALGQPPLVVVLDGIQDPHNLGAIIRSADALGAHGVVIAKDRAV 166

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T+A A+AG+    ++     I  A+  LK  G+ + A  + D            P 
Sbjct: 167 QVTGTVAKASAGAVEHSRIARVVNISRALEELKEAGLWVAAADV-DAKEPMWSARLDGPL 225

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            +++G E  G+    L   D  + IPM G V SLN SV++ ++LYE  RQR
Sbjct: 226 ALVVGAEGAGVRDGVLKHCDFRLRIPMAGQVGSLNASVSAGILLYEVARQR 276


>UniRef50_C4V0H0 tRNA/rRNA methyltransferase n=1 Tax=Selenomonas flueggei ATCC 43531
           RepID=C4V0H0_9FIRM
          Length = 272

 Score =  199 bits (508), Expect = 5e-50,   Method: Composition-based stats.
 Identities = 53/172 (30%), Positives = 89/172 (51%), Gaps = 7/172 (4%)

Query: 1   MNPTRYARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P  Y  + E++A    R +  L + ++ +  P N+ A++RTADA GVH +      S 
Sbjct: 97  VAPVAYVAVEEVIAGARARGEDPLLLLLDGIEDPQNLGALLRTADAAGVHGILLPRRHSV 156

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T+A  +AG+  +V V     I   +  LK QG  I    +    + +   + T   
Sbjct: 157 PLTETVARVSAGALEYVPVARIGNIAQTIRALKEQGFWIAGADMGGEEI-YDRANLTGAL 215

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            +++G E  G+++    L D  + +PM+G + SLN SVA A+++YEAQRQR+
Sbjct: 216 VLVIGSEGRGMSRLTRDLCDFTVRLPMMGKINSLNASVAGAILMYEAQRQRR 267


>UniRef50_B8D0A6 RNA methyltransferase n=11 Tax=Firmicutes RepID=B8D0A6_HALOH
          Length = 244

 Score =  199 bits (507), Expect = 6e-50,   Method: Composition-based stats.
 Identities = 49/171 (28%), Positives = 84/171 (49%), Gaps = 9/171 (5%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT- 59
           ++P     I     + +    + ++QV  PHN+ AIIRTA A G H +  ++P  R    
Sbjct: 78  VSPREMVEIAR--EKGEDPFIIILDQVQDPHNLGAIIRTAYAAGAHGL--IYPRKRSADI 133

Query: 60  ---MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
              +  A+AG+ + + +     I   +A LK  G+ I  T +      +   DY  P  +
Sbjct: 134 TPVVTKASAGAVNHLPLAKVSNINYTIADLKDMGLWITGTDVR-GTRPYYSADYKGPVGL 192

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           ++G E  G+ +      D  + IPM G + SLN SVA+ ++++E  RQR++
Sbjct: 193 VIGNEGKGMRRLVKENCDFVVNIPMSGELGSLNASVAAGVVIFEVVRQRRS 243


>UniRef50_Q82XD1 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=112
           Tax=Proteobacteria RepID=RLMB_NITEU
          Length = 260

 Score =  199 bits (507), Expect = 6e-50,   Method: Composition-based stats.
 Identities = 50/165 (30%), Positives = 80/165 (48%), Gaps = 4/165 (2%)

Query: 4   TRYARICEMLAR-RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTM 60
            RYA + ++L    +P L + ++ V  PHN+ A +R ADA GVH V      +     T+
Sbjct: 80  RRYATLEDLLEGLTEPALLLVLDGVKDPHNLGACLRVADAFGVHAVVVPKDRAVGLSATV 139

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A+G+   V       +   +  LK  G+ I+ T  +D       +  TRP   ++G 
Sbjct: 140 HKVASGAVDTVPFFAVTNLARTLRELKEMGLWIVGTA-ADAPDTLDSVTLTRPLAWVLGA 198

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           E  G+ +      D  + IPM G ++SLNVSV++ + L+E  RQ 
Sbjct: 199 EDGGMRRLTREACDLLVSIPMSGSIESLNVSVSAGICLFETFRQH 243


>UniRef50_C5NV68 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Gemella
           haemolysans ATCC 10379 RepID=C5NV68_9BACL
          Length = 271

 Score =  199 bits (507), Expect = 7e-50,   Method: Composition-based stats.
 Identities = 50/167 (29%), Positives = 86/167 (51%), Gaps = 9/167 (5%)

Query: 1   MNPTRYARICEMLAR---RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM 57
           + P  Y  + E++      +    + ++ +  PHN+ AIIRTA+A GV  +  + P  R 
Sbjct: 101 VAPYSYFELDEVVNNLEINKDTTLLILDHIEDPHNLGAIIRTAEASGVKAI--IIPKRRA 158

Query: 58  RTM----ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
             +      A+AG+   + V     + DA+  LK +G  I  T L++ + D+ +I    P
Sbjct: 159 AVVSQTAVKASAGAIEHMPVIRVSNLTDAIKKLKEKGFWIAGTTLAERSEDYTKIAKDVP 218

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYE 160
             I++G E  G+++      D    +PM+G +QSLN SVA+ +I+YE
Sbjct: 219 LAIVIGNEGEGMSKVVTNECDFLYHLPMLGKIQSLNASVAAGIIMYE 265


>UniRef50_C8WTZ2 RNA methyltransferase, TrmH family, group 3 n=2
           Tax=Alicyclobacillus acidocaldarius RepID=C8WTZ2_ALIAD
          Length = 255

 Score =  198 bits (505), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 56/169 (33%), Positives = 88/169 (52%), Gaps = 5/169 (2%)

Query: 1   MNPTRYARICEMLARRQ--PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
           + P  Y  + +++ R      L V ++++  PHN  AI+RTA+A G   V          
Sbjct: 87  VAPYAYVDLDDVIRRDTGFAPLVVVLDEIADPHNFGAILRTAEASGAQGVVIGKRRQAQV 146

Query: 59  T--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
           T  +A AAAG+   + V     +  A+  LK  G  I+   + +  V + E+DY  PT +
Sbjct: 147 TDVVAKAAAGALETLPVARVANVAQALQRLKQAGYWIVGADV-EAKVPYTEVDYRGPTAV 205

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           ++G E  G+ +      D  + IP++G VQSLN SVA+ ++LYEA RQR
Sbjct: 206 VIGSEGQGMRRWVREQCDFLVSIPILGRVQSLNASVAAGVLLYEAVRQR 254


>UniRef50_B8HJN1 RNA methyltransferase, TrmH family, group 3 n=6 Tax=Bacteria
           RepID=B8HJN1_CYAP4
          Length = 387

 Score =  198 bits (504), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 50/172 (29%), Positives = 82/172 (47%), Gaps = 6/172 (3%)

Query: 1   MNPTRYARICEMLARRQ---PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           + P  Y  +  +L   Q     + +  + +  PHN+ AIIRTA+A+G   +      +  
Sbjct: 198 VAPYSYLELDTLLENIQGLDHPVLLAADGITDPHNLGAIIRTAEALGAQGLVVPQRRAVG 257

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T+A  AAG+     V     +  A+  LK  G  I     +  A     ++++ P  
Sbjct: 258 ITSTVAKVAAGALEHFAVARVVNLNQALEQLKAAGFWIYGMAATA-AKPIYSVEFSGPVV 316

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           +++G E TG++  A    DQ + IP++G   SLN SVA+ + LYE  RQR +
Sbjct: 317 LVVGAEGTGLSLLAQRYCDQLVSIPLLGKTPSLNASVATGMALYEIFRQRSS 368


>UniRef50_Q7NYX3 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=23
           Tax=Proteobacteria RepID=RLMB_CHRVO
          Length = 248

 Score =  198 bits (504), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 55/167 (32%), Positives = 83/167 (49%), Gaps = 5/167 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--R 58
           MN      + E L+  +P L + ++ V  PHN+ A +R ADA+G H V A    S     
Sbjct: 80  MNYVDLDDVLENLS--EPPLLLILDGVTDPHNLGACLRVADAMGAHAVIAPKDRSATLNA 137

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
           T++  A G+   V   T   +   +  LK  G+ I  T +  +  D    D + P   +M
Sbjct: 138 TVSKVACGAAEVVPYITVTNLARTLRDLKDAGVWIAGTTMEAD-TDLYHFDASGPLAWVM 196

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           G E  G+ +      D  + IPM G V+SLNVSV+S ++L E++RQR
Sbjct: 197 GAEGEGMRRLTREHCDVLVSIPMFGTVESLNVSVSSGMVLSESRRQR 243


>UniRef50_Q7MBB6 tRNA/rRNA methyltransferase n=1 Tax=Gloeobacter violaceus
           RepID=Q7MBB6_GLOVI
          Length = 338

 Score =  198 bits (504), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 45/169 (26%), Positives = 77/169 (45%), Gaps = 3/169 (1%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASA 63
           +  +   L  R   + +  + +  PHN+ A+IR+A+A G   +      +     T+A  
Sbjct: 170 FEELIASLVERPDPVLLAADGIEDPHNLGALIRSAEAFGFQGIILPQRRAVGVTATVAKV 229

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           AAG+   + +     +  A+  LK  G Q++ T     +    E+    P  +++G E  
Sbjct: 230 AAGAVEHLPIARVTNLNQAIERLKEAGYQVVGT-QEKASQALYELKLDGPLVVVVGSEGK 288

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYL 172
           GI+       D  + IP+ G   SLN SVA  ++LYE  RQR+   + L
Sbjct: 289 GISLLTQRHCDHMVSIPLAGKTTSLNASVAGGIMLYEVMRQRRANQIDL 337


>UniRef50_Q1ISZ4 RNA methyltransferase TrmH, group 3 n=2 Tax=Acidobacteria
           RepID=Q1ISZ4_ACIBL
          Length = 261

 Score =  198 bits (504), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 46/166 (27%), Positives = 80/166 (48%), Gaps = 6/166 (3%)

Query: 6   YARICEMLARR--QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMA 61
           Y  + +++ ++  +    V ++ +  PHN+ A+IR+AD  GV  V      +     T  
Sbjct: 78  YLDLDDIIEKKRGEHAFVVVLDGIEDPHNLGALIRSADGAGVDGVVIPERRAVGVTGTAM 137

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQ-GMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
            A+AG+  +V +     I  ++  LK +  +  +         ++ EIDY     +++G 
Sbjct: 138 KASAGAAEYVPIARVTNIARSIEDLKDKYNVWTVGLD-ERGTQNYDEIDYNMSLALVLGA 196

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           E  G+        D  + IPM G V SLNVSVA  +++YE  RQR+
Sbjct: 197 EGKGLHDLVRKKCDLLVKIPMAGEVSSLNVSVAGGIVMYEVSRQRR 242


>UniRef50_A1HPG2 TRNA/rRNA methyltransferase (SpoU) n=1 Tax=Thermosinus
           carboxydivorans Nor1 RepID=A1HPG2_9FIRM
          Length = 270

 Score =  197 bits (503), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 55/160 (34%), Positives = 88/160 (55%), Gaps = 3/160 (1%)

Query: 11  EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR--TMASAAAGSN 68
           + L     +L V ++ V  P NV  ++RTADA G   V      + +       A  GS 
Sbjct: 110 DDLQSSDRELIVVLDNVQDPGNVGTVVRTADAAGCCGVILTKGCADLFSGKTVRATMGSL 169

Query: 69  SWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQE 128
             + V T     +  A L+ QG+++LAT L  +++ + ++D   P  I+ G E  G+++ 
Sbjct: 170 FHLPVITGVAEQEVAAFLERQGIRLLATALDSSSL-YHDVDLRSPVAIVFGNEGAGVSKV 228

Query: 129 ALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
            L  AD+ + IP+ G  +SLNV+VA+A+ILYEA+RQR+ A
Sbjct: 229 ILEKADERLYIPLYGRAESLNVAVAAAVILYEARRQRRVA 268


>UniRef50_B8G1U5 RNA methyltransferase, TrmH family, group 3 n=4 Tax=Firmicutes
           RepID=B8G1U5_DESHD
          Length = 246

 Score =  197 bits (503), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 51/171 (29%), Positives = 83/171 (48%), Gaps = 8/171 (4%)

Query: 1   MNPTRYARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P  YA + ++LA    + +    + +++V  PHN+ A+IRTADA GVH V      S 
Sbjct: 74  VAPREYAEVDDILALAGEKGEDPFILVLDEVEDPHNLGALIRTADAAGVHGVIIPKRRSV 133

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T+A  +AG+   V V     +   +  L+  G  +         V     D T   
Sbjct: 134 SLTATVAKTSAGAVEHVLVARVGNLVQTLKDLQKAGCWVSGAEAEGTEV--YRSDLTGAR 191

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            I++G E  G+++      D+ + +PM G + SLN SVA ++++YE  RQR
Sbjct: 192 VIVIGSEGKGLSRLVKETCDEIVSLPMKGRINSLNASVAGSILMYEVLRQR 242


>UniRef50_A8PMQ1 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Rickettsiella
           grylli RepID=A8PMQ1_9COXI
          Length = 253

 Score =  197 bits (502), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 45/152 (29%), Positives = 72/152 (47%), Gaps = 3/152 (1%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVK 74
            P   + ++ V  PHN+ A +R+A+A GV  V      +  +T  +   AAG+     + 
Sbjct: 103 NPPFLLVLDGVQDPHNLGACLRSANAAGVDAVIIPQDRAVNKTPIVQKTAAGAAEVTSLF 162

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
           T   +   +  LK  G+       S   +   +   T P  +++G E  G+ +      D
Sbjct: 163 TVTNLATCLERLKKCGIWCYGLDQSGTRL-IYDAPLTGPLALVLGAEGKGLRRLTKVCCD 221

Query: 135 QDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
             + IPM+G V SLNVSVA+ + L+E  RQRQ
Sbjct: 222 DLVAIPMVGTVGSLNVSVAAGVGLFEVVRQRQ 253


>UniRef50_A8RFN1 Putative uncharacterized protein n=2 Tax=Erysipelotrichaceae
           RepID=A8RFN1_9FIRM
          Length = 241

 Score =  197 bits (502), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 51/171 (29%), Positives = 84/171 (49%), Gaps = 6/171 (3%)

Query: 1   MNPTRYARICEMLA---RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           ++  +   I E++A   + +  L V ++++  PHN+ AI+RT D VGV  V         
Sbjct: 70  IDDYKTYTIEELVAGVPKGKTPLFVMLDELEDPHNLGAILRTCDCVGVDGVIIGKHRGVK 129

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T+A  + G+   V+V     +   +  LK +G  +      DN+ D+R+  Y  P  
Sbjct: 130 LTPTVAKVSTGAIDTVKVAVVTNLAQTLKGLKKEGFWVAGADF-DNSQDYRQASYDMPLV 188

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           +++G E  GI+       D  + +PM G V SLN SVA A++LY+   QR 
Sbjct: 189 LVVGSEGFGISPLVKKNCDFFVRLPMEGSVSSLNASVACAVLLYQIYAQRN 239


>UniRef50_Q2LQ81 23S rRNA Gm2251 methyltransferase n=1 Tax=Syntrophus aciditrophicus
           SB RepID=Q2LQ81_SYNAS
          Length = 249

 Score =  197 bits (502), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 46/170 (27%), Positives = 78/170 (45%), Gaps = 7/170 (4%)

Query: 2   NPTRYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG--S 55
              RY  +  ++A R P    DL + ++ +  PHN+ A+IR+A   G + +        S
Sbjct: 74  TAYRYQDLDAVIANRHPSCPYDLVLILDGILDPHNLGALIRSAHCFGANGIILPERRAAS 133

Query: 56  RMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T+   +AG+   + +     +  A+  LK +G  I       +     + DY     
Sbjct: 134 VTGTVIKTSAGAARHIPIARVANLARALDELKTKGFWIFGADARAD-QSVSDPDYQGAVG 192

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           ++MG E  G+        D  I IPM+G + SLNVSV+  +IL+E +R+ 
Sbjct: 193 LVMGGESKGLRPLIRKKCDDLISIPMLGKIDSLNVSVSGGIILHEIRRKN 242


>UniRef50_A6CBV4 YacO n=1 Tax=Planctomyces maris DSM 8797 RepID=A6CBV4_9PLAN
          Length = 261

 Score =  197 bits (501), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 45/172 (26%), Positives = 85/172 (49%), Gaps = 6/172 (3%)

Query: 1   MNPTRYARICEMLARRQ--PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVH--AVWPGSR 56
           M P  Y  I E+  +++    L + ++++  P N  AIIR+A+ +G   +          
Sbjct: 92  MAPFPYTSI-ELFNQQEITSPLFLILDRIQDPFNFGAIIRSAEIMGADGIFSGTHEQCEV 150

Query: 57  MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
              +   +AG+ + V +     +       K  G+ I+ T +   +    + ++ +PT +
Sbjct: 151 TSLVCRTSAGAVNHVPLVQATDLVSLCRDWKQNGINIVGTAM-QASEKLNDYNFQQPTAV 209

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           ++G E TGI+ E  A     + IP  G  +SLNV+V+++++LYEA RQR  +
Sbjct: 210 IVGNEGTGISPELQAECTHLVRIPQQGKTESLNVAVSASILLYEASRQRNFS 261


>UniRef50_B5EQA2 RNA methyltransferase, TrmH family, group 3 n=3
           Tax=Acidithiobacillus RepID=B5EQA2_ACIF5
          Length = 255

 Score =  196 bits (500), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 47/151 (31%), Positives = 77/151 (50%), Gaps = 3/151 (1%)

Query: 19  DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP--GSRMRTMASAAAGSNSWVQVKTH 76
              + ++ V  PHN+ A +R+A+A GV  V            T+  A+AGS S V V T 
Sbjct: 93  GFLLVLDGVLDPHNLGACLRSAEAAGVDAVILPRDNACPVNATVRKASAGSASRVPVCTV 152

Query: 77  RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQD 136
             +   ++ L+  G  ++     + +     +D   P  ++MG E+ G+ +      D  
Sbjct: 153 TNLSRTLSSLQEAGFWLVGMA-GEGSRSLYALDLDMPLVMVMGGEEKGLRRLTREHCDYL 211

Query: 137 IIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
             IPM+G ++SLNVSVA+ + L+EA RQR+N
Sbjct: 212 AHIPMMGAIESLNVSVATGICLFEAARQRRN 242


>UniRef50_A0L4P9 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Magnetococcus
           sp. MC-1 RepID=A0L4P9_MAGSM
          Length = 246

 Score =  196 bits (499), Expect = 5e-49,   Method: Composition-based stats.
 Identities = 47/163 (28%), Positives = 79/163 (48%), Gaps = 6/163 (3%)

Query: 7   ARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA----S 62
             + +++ + +  L V ++ V  PHN+ AI+R+A+A G   V    P  R   +      
Sbjct: 84  DDLLDVVEKAKQPLLVILDGVEDPHNLGAIMRSAEAFGALAVIL--PKDRTAPLNAGAIK 141

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
           A+AG+   + +     +  A+  L+ + + ++       A     +D   P  ++MG E 
Sbjct: 142 ASAGAAERLDLIRVTNLARAIEQLQQRNVWVIGLAGEAGAPLIGTLDCKGPLALVMGNEG 201

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +G+ +      DQ   IPM G V SLNVSVA+ + LYE  RQR
Sbjct: 202 SGLRRLTRERCDQLAAIPMGGGVGSLNVSVATGVALYEVLRQR 244


>UniRef50_Q83CW6 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=19
           Tax=Proteobacteria RepID=RLMB_COXBU
          Length = 250

 Score =  196 bits (498), Expect = 7e-49,   Method: Composition-based stats.
 Identities = 49/163 (30%), Positives = 81/163 (49%), Gaps = 4/163 (2%)

Query: 7   ARICEMLARRQ-PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASA 63
           + +  +L +R+ P L + ++ V  PHN+ A +R+A+A GV  V A    +      +   
Sbjct: 84  SALLSLLKKRETPALLLILDGVKDPHNLGACLRSANAFGVRAVIAPKDRAVGVTPVVRKV 143

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           A G+           +   +  L+ +G+ I+ T +    +  +EID T    I++G E  
Sbjct: 144 ACGAAEMTPFIRVTNLSRTIDWLQKEGVWIVGTAVEAETL-IQEIDLTGDIAIVLGSEGA 202

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           G+ +      D    IP+ G V+SLNVSVA  + LYE QRQR+
Sbjct: 203 GLRRLTKERCDFLAQIPLRGSVESLNVSVACGICLYEVQRQRE 245


>UniRef50_C7REQ2 RNA methyltransferase, TrmH family, group 3 n=4 Tax=Anaerococcus
           RepID=C7REQ2_ANAPD
          Length = 234

 Score =  195 bits (497), Expect = 8e-49,   Method: Composition-based stats.
 Identities = 43/147 (29%), Positives = 72/147 (48%), Gaps = 3/147 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW--PGSRMRTMASAAAGSNSWVQVKTHRT 78
            + ++++  PHN+ AIIR+A++ G   V        S   T+   +AG+ + ++V     
Sbjct: 86  LIILDKIEDPHNLGAIIRSAESFGFDAVIIPERRSASVTSTVYKTSAGAINNIKVVRVTN 145

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           +   +  LK +G  I       ++ D    D      +++G E  GI++      D  I 
Sbjct: 146 LTRTIKDLKDKGFWIYGLAGEAHS-DISHADLRGKVGLVVGNEGEGISRLVRENCDMLIN 204

Query: 139 IPMIGMVQSLNVSVASALILYEAQRQR 165
           IPM+G V SLN SVA+A+ +YE  RQ 
Sbjct: 205 IPMLGRVNSLNASVAAAISMYELLRQN 231


>UniRef50_A4XJ85 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Clostridia
           RepID=A4XJ85_CALS8
          Length = 253

 Score =  195 bits (497), Expect = 9e-49,   Method: Composition-based stats.
 Identities = 46/172 (26%), Positives = 82/172 (47%), Gaps = 7/172 (4%)

Query: 4   TRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVH--AVWPGSRM 57
            +Y  I ++L     + +    V ++++  PHN  +IIR+A   G H +   A       
Sbjct: 75  YKYWDIDDLLLEAANKGEKPFLVLLDEITDPHNFGSIIRSAHLCGAHGIITEARNSCPIT 134

Query: 58  RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
            T+  A+AG+   ++V     +   +  LK +G+ + A   +     + + D+  P CI+
Sbjct: 135 PTVEKASAGAIEHIKVARVVNLRRTIDSLKEKGVWVYAADNNAEKFVY-DCDFKIPICII 193

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
           +G E  GI++     AD  + IP  G + S N SVA+ +I +E  +QR   G
Sbjct: 194 IGSEGKGISRLVKEGADFLVKIPQKGKINSYNASVAAGIIFFEVLKQRMQEG 245


>UniRef50_Q14PR4 Putative trna/rrna methyltransferase protein n=1 Tax=Spiroplasma
           citri RepID=Q14PR4_SPICI
          Length = 244

 Score =  195 bits (497), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 57/163 (34%), Positives = 88/163 (53%), Gaps = 4/163 (2%)

Query: 3   PTRY--ARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG--SRMR 58
           P  Y  A I     + +    + ++Q+  PHN  AI+RT D   V  V  +         
Sbjct: 77  PQNYSLASITTKALQNKHPFLLVLDQISDPHNFGAILRTCDLFNVDGVIILDKRQVDINA 136

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
           T+A  +AG+ ++V V     + +A+ +LK QG  I AT L+  A +  E+ Y  P C+++
Sbjct: 137 TVAKTSAGAFNYVPVCRVNNLTNAIEYLKKQGFWIYATSLNTKAQNVSELKYDIPICLIV 196

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEA 161
           G E TGI+ + L  AD +I IP  G + SLNVSVASA+++Y+ 
Sbjct: 197 GNEGTGISAKLLKHADFNIYIPTAGHLDSLNVSVASAILIYQI 239


>UniRef50_Q724H1 RNA methyltransferase, TrmH family, group 3 n=21 Tax=Firmicutes
           RepID=Q724H1_LISMF
          Length = 251

 Score =  195 bits (497), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 48/154 (31%), Positives = 84/154 (54%), Gaps = 3/154 (1%)

Query: 14  ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSNSWV 71
           A+ +    + ++++  PHN+ +I+RTAD+VG H +      S    +T+A A+ G+  +V
Sbjct: 94  AKDEMPFFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTGAMEYV 153

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            V     +   +  L+ +G+ I  T  +  + D+R +D   P  I++G E  G++     
Sbjct: 154 PVVRVTNMVRTMEELQKRGLWIFGTD-AKGSSDYRTMDVDMPLAIVIGSEGFGMSCLVRE 212

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             D  + +PM G V SLN SVA++L+LYE  R+R
Sbjct: 213 KCDFLVHLPMRGKVTSLNASVAASLLLYEVYRKR 246


>UniRef50_Q9LXE4 rRNA methylase-like protein n=11 Tax=Magnoliophyta
           RepID=Q9LXE4_ARATH
          Length = 350

 Score =  194 bits (495), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 62/191 (32%), Positives = 98/191 (51%), Gaps = 5/191 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAV--WPGSRMR 58
           M   R  R   ++  R   + + +E +    N+SA  R+ADA+G+  VH V      R  
Sbjct: 136 MMEERTDRFRRVVENRSYSVCLVVEGLSDFGNISAAFRSADALGIQSVHVVSCDSSKRYN 195

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
                + G+  W+ ++   T  +    LK +G +I  THL  + V   ++D++ PT I++
Sbjct: 196 GNRHVSMGAEKWLDIEFWDTPKECFKVLKSRGYRIATTHLGMDTVSIYDMDWSCPTAIVV 255

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSML 178
           G E  GI+ EAL L+D    IPM GMV S NVSVA+ ++++ A   R      L  +  L
Sbjct: 256 GNEGRGISDEALELSDLRCSIPMNGMVDSFNVSVAAGILMHHAVSDRTT---RLGSHGDL 312

Query: 179 PEAEQQRLLFE 189
            EAE++ L+ E
Sbjct: 313 SEAEKEILMAE 323


>UniRef50_D1AP92 RNA methyltransferase, TrmH family, group 3 n=7
           Tax=Fusobacteriaceae RepID=D1AP92_SEBTE
          Length = 234

 Score =  194 bits (493), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 42/163 (25%), Positives = 78/163 (47%), Gaps = 6/163 (3%)

Query: 6   YARICEMLAR---RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTM 60
           Y  + E L +   +Q  + + ++Q+  P N  AIIR+A+  GV  +      S     T+
Sbjct: 71  YLELNEFLEKVLAKQRSIVLVLDQIQDPRNFGAIIRSAECFGVDGIIIQDRNSVSVTETV 130

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
             ++ G+   V +     + D++  LK  G  I     +D   ++    +    C+++G 
Sbjct: 131 VKSSTGAIEHVDIIKVTNVSDSMDKLKKYGYFIYGAE-ADGETEYYNEPFPEKLCLVLGS 189

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           E  G+ ++     D+ + IPM G + SLNVSVA+ ++L E  +
Sbjct: 190 EGKGMRKKVKEHCDKILNIPMHGKINSLNVSVANGILLAEISK 232


>UniRef50_A7HLT3 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Thermotogaceae
           RepID=A7HLT3_FERNB
          Length = 234

 Score =  193 bits (492), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 4/150 (2%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM--ASAAAGSNSWVQVK 74
           +    V ++QV  P N+ AI+RTA A GV+ V      S   T     A+AG+   + + 
Sbjct: 83  ENPFIVLLDQVQDPQNLGAIVRTAVAAGVNMVVLTKDNSAHVTPGSIKASAGTIFRIPIV 142

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
               +   +  LK +G+ I    +        E+   RP  I+ G E +GI Q      D
Sbjct: 143 ITVNLARYIEKLKDKGVWIYGADMRGK--PLWEVKLERPLGIVFGNEGSGIRQLVKESCD 200

Query: 135 QDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           + + IPM   + SLNVSV++ +++YE  R+
Sbjct: 201 ELVSIPMKTPIDSLNVSVSAGILIYEVLRR 230


>UniRef50_C7H0N3 RNA methyltransferase, TrmH family n=1 Tax=Eubacterium saphenum
           ATCC 49989 RepID=C7H0N3_9FIRM
          Length = 297

 Score =  193 bits (492), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 45/173 (26%), Positives = 81/173 (46%), Gaps = 8/173 (4%)

Query: 1   MNPTRYARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
            N   Y  I + L     R +  L + ++++  P N+ AIIRTA   GVH +      + 
Sbjct: 126 FNKFAYRDIDDALRLADIRGEKPLVLVLDRIEDPRNLGAIIRTARCAGVHGIIIAKDRAA 185

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T+A  + G+   +       +  A+  LK +G  + A   + ++    E ++    
Sbjct: 186 GITPTVAKVSEGAIFSIPCIMVTNLAAALKDLKQRGFWVYAADANGDS--CFEQEFGGSV 243

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
            +++G E  GI++  L  +D  + IPM+    SLNVSVA+ +++YE  R+   
Sbjct: 244 ALVLGNEGKGISKLCLNESDYKVSIPMVNDFDSLNVSVAAGILMYEIVRKNNR 296


>UniRef50_D1U4M7 tRNA guanosine-2'-O-methyltransferase n=1 Tax=Desulfovibrio
           aespoeensis Aspo-2 RepID=D1U4M7_9DELT
          Length = 226

 Score =  193 bits (491), Expect = 5e-48,   Method: Composition-based stats.
 Identities = 76/197 (38%), Positives = 110/197 (55%), Gaps = 9/197 (4%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           ++  R  RI ++LARRQ DLT+ M+ +  PHNVSA++R+ DA GV +VH  +  S+   +
Sbjct: 25  ISDKRKQRIDQVLARRQKDLTLVMDNIWDPHNVSAVLRSCDAFGVSDVHLYYTTSQWPDL 84

Query: 61  ASAAAG-SNSWVQVKTHRTIGDAVAHL------KGQGMQILATHLSDNAVDFREIDYTRP 113
              ++G +  W+++  H      V +L         G QIL T  S  A    + D+T P
Sbjct: 85  GKKSSGSAMKWIRLIRHVDAATMVGNLVGGGGSAHDGGQILRTGFSATARPVMDFDFTIP 144

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLR 173
           T I++  E  G + E  AL   ++ IPM GMVQSLNVSVA+A+ILYEA  QR+ AG+Y  
Sbjct: 145 TAIILSNEHRGTSPELAALVPDEVYIPMQGMVQSLNVSVAAAIILYEAFTQRKRAGLY-- 202

Query: 174 ENSMLPEAEQQRLLFEG 190
           +     + E   L  E 
Sbjct: 203 DAPSFSDEELAALRAEW 219


>UniRef50_C8WR00 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Bacillales
           RepID=C8WR00_ALIAD
          Length = 256

 Score =  192 bits (490), Expect = 5e-48,   Method: Composition-based stats.
 Identities = 64/194 (32%), Positives = 93/194 (47%), Gaps = 3/194 (1%)

Query: 12  MLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWV 71
           +L RR   + V ME V   HN +AI+R+A+A GV  V  +              G++ W+
Sbjct: 41  VLMRRTSYIAVAMEAVDDGHNQAAILRSAEAFGVQHVAVIEGKQPFHPSKGVTQGAHKWL 100

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            ++    IG A+  L  +G Q+ AT L + A     +D  RPT IL G EK G++ EA  
Sbjct: 101 TLQRMPDIGRAIDALHARGFQVYATDLGEGAQPIDAVDLARPTAILFGNEKDGVSPEARE 160

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAEQQRLLFEGG 191
            AD    IPM G VQS NVSVA+A+ LYE  R+ +     + +   L   E+ +L     
Sbjct: 161 RADGRFYIPMAGFVQSFNVSVAAAIALYELTRRARET---VGDRYALGADERHKLYVTWC 217

Query: 192 YPVLAKVAKRKGLP 205
              L    + +   
Sbjct: 218 LRSLHGATREEARR 231


>UniRef50_A6BKK3 Putative uncharacterized protein n=6 Tax=Bacteria
           RepID=A6BKK3_9FIRM
          Length = 265

 Score =  192 bits (490), Expect = 5e-48,   Method: Composition-based stats.
 Identities = 44/170 (25%), Positives = 79/170 (46%), Gaps = 8/170 (4%)

Query: 4   TRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--M 57
             YA + +ML     + +    + ++ +  PHN+ AIIRTA+  G H V      +    
Sbjct: 98  YEYAEVEDMLKLAEEKGEDPFLIILDNIEDPHNLGAIIRTANQAGAHGVIIPKRRAVGLT 157

Query: 58  RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
            T+A  +AG+ ++  V     +   +  LK +G+  +   +  +     +++   P  ++
Sbjct: 158 ATVARTSAGALNYTPVAKVTNLVKTMEDLKKKGLWFVCADMDGD--VMYDVNMKGPIGLV 215

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           +G E  G+ +      D    IPM G + SLN SVA+ ++ YE  RQR  
Sbjct: 216 IGNEGEGVGRLVKDTCDFTARIPMKGDIDSLNASVAAGVLAYEIVRQRMQ 265


>UniRef50_C1F8Y2 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Acidobacterium
           capsulatum ATCC 51196 RepID=C1F8Y2_ACIC5
          Length = 270

 Score =  192 bits (490), Expect = 6e-48,   Method: Composition-based stats.
 Identities = 46/163 (28%), Positives = 76/163 (46%), Gaps = 3/163 (1%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASA 63
              +    A   P L + ++ V  P N+ A++R+AD  GV  V      S          
Sbjct: 85  IEDLMAAPADGHPHLLLALDGVEDPQNLGALLRSADGAGVDGVLLPERRSAPLSAVAVKT 144

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           +AG+   +++     +  A+  LK Q +  +        + +   D+T P+ +++G+E  
Sbjct: 145 SAGAAEHIRIARVVNLVRALEQLKEQNIWCVGLD-ERGTMSYDAYDWTTPSVVVLGREGE 203

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           G+        D  + IPM G V SLNVS A A++LYEA RQR+
Sbjct: 204 GLHDLVRKTCDHLVRIPMAGGVSSLNVSAAGAVVLYEAARQRR 246


>UniRef50_C2BF70 tRNA/rRNA methyltransferase n=1 Tax=Anaerococcus lactolyticus ATCC
           51172 RepID=C2BF70_9FIRM
          Length = 239

 Score =  192 bits (489), Expect = 7e-48,   Method: Composition-based stats.
 Identities = 41/150 (27%), Positives = 72/150 (48%), Gaps = 3/150 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW--PGSRMRTMASAAAGSNSWVQVKTHRT 78
            + ++Q+  PHN+ AIIR+A++ G   V        S    +   +AG+ + + +   + 
Sbjct: 91  LIILDQIEDPHNLGAIIRSAESFGFDGVIIPERRSASVSPIVYKTSAGAINNINIIMVKN 150

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
              A+  +K  G  +      + +    ++D     C+++G E  G+++      D  I 
Sbjct: 151 TNRAIEEIKEAGFWVYGLA-GEASSPIDQVDLKGKVCLIVGNEGKGLSRLVRENCDILIN 209

Query: 139 IPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           IPM G V SLN SVASA+ +YE  RQ   +
Sbjct: 210 IPMKGFVNSLNASVASAIAMYEVLRQNGFS 239


>UniRef50_C0GIN0 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Dethiobacter
           alkaliphilus AHT 1 RepID=C0GIN0_9FIRM
          Length = 245

 Score =  192 bits (489), Expect = 7e-48,   Method: Composition-based stats.
 Identities = 48/168 (28%), Positives = 79/168 (47%), Gaps = 5/168 (2%)

Query: 3   PTRYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MR 58
           P RY    ++LA+   +P   V ++ +  PHN+ A+IRTA A G   +      +     
Sbjct: 77  PFRYTPFADILAKAGDKPPFLVLLDHIQDPHNLGALIRTAYAAGCDGIIIPERRAAQMTP 136

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
                AAG+  ++ V     +   +   K  G+ +    +   +V +   DY   T +++
Sbjct: 137 AAVRTAAGAAEYLPVAKVVNLARCLDECKDAGLWVYGADMDGESV-YTTGDYQGGTVLVI 195

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           G E  G+ +      D  + +PM G V SLN SVA AL++YE  RQR+
Sbjct: 196 GSEGEGLGRLVKEKCDHLVQLPMQGKVASLNASVAGALLMYEVYRQRE 243


>UniRef50_Q1LSR1 RNA methyltransferase, TrmH family, group 3 n=4
           Tax=Gammaproteobacteria RepID=Q1LSR1_BAUCH
          Length = 248

 Score =  192 bits (489), Expect = 8e-48,   Method: Composition-based stats.
 Identities = 45/165 (27%), Positives = 82/165 (49%), Gaps = 3/165 (1%)

Query: 7   ARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAA 64
             +  +LA+    L + ++ V  PHN+ A +R ADA GV+ +      S     T+   A
Sbjct: 84  QDLPALLAQHTAPLLLVLDGVTDPHNLGACLRCADAAGVNAIIIPRNRSAYLNATVKKVA 143

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFRE-IDYTRPTCILMGQEKT 123
           +G+   + +     +   +  L+   + IL T +  ++  ++    +T P  +++G E  
Sbjct: 144 SGAAETMPLIQVTNLARTLRLLQEHNILILGTTIEADSHIYQTSFKFTSPIALVVGAEGN 203

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           GI +      ++ + IPM+G V SLNVSVA  + L+E  RQR ++
Sbjct: 204 GIRRLTKKYCNELLRIPMVGSVASLNVSVAVGVFLFEVVRQRLSS 248


>UniRef50_B7DP24 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Alicyclobacillus
           acidocaldarius LAA1 RepID=B7DP24_9BACL
          Length = 249

 Score =  191 bits (487), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 68/195 (34%), Positives = 96/195 (49%), Gaps = 5/195 (2%)

Query: 12  MLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWV 71
           +L RR   + V ME V   HN +AI+R+A+A GV  V  +      +       G++ W+
Sbjct: 37  VLMRRTGYIAVAMEAVDDGHNQAAILRSAEAFGVQHVAVIEGKQPFQPSKGVTQGAHKWL 96

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            +    ++G A+  L  +G Q+ AT L D A     +D  RPT IL G EK G++ EA  
Sbjct: 97  TIHRMPSVGRAIDALHARGFQVYATDLGDGAEPIDAVDLARPTAILFGNEKDGVSPEARE 156

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQ-RQNAGMYLRENSMLPEAEQQRLLFEG 190
            AD    IPM G VQS NVSVA+A+ LYE  R+ R+ AG    +   L   E+ RL    
Sbjct: 157 RADGRFYIPMAGFVQSFNVSVAAAIALYELTRRARETAG----DRYALDADERHRLYVTW 212

Query: 191 GYPVLAKVAKRKGLP 205
               L    + +   
Sbjct: 213 CLRSLHGATREEARR 227


>UniRef50_B9ZJH8 RNA methyltransferase, TrmH family, group 3 n=1
           Tax=Thioalkalivibrio sp. K90mix RepID=B9ZJH8_9GAMM
          Length = 251

 Score =  191 bits (486), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 53/150 (35%), Positives = 76/150 (50%), Gaps = 3/150 (2%)

Query: 19  DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAGSNSWVQVKTH 76
           DL + ++ V  PHN+ A +RTADA G   +      S   T A    A+G+   V V   
Sbjct: 102 DLVLVLDGVTDPHNLGACLRTADAAGAGAIVTPRHHSAALTPAAIKVASGAAETVPVVAV 161

Query: 77  RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQD 136
             +   +A LK  GM  +    + +  D   +D   PT I+MG E  G+ +      D  
Sbjct: 162 GNLARTLAALKDAGMWTVGLDGAAHE-DLYAVDLRPPTAIVMGAEGEGMRRLTREACDHL 220

Query: 137 IIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
             IPM G V+SLNVSVA+ + L+EA+RQR+
Sbjct: 221 ARIPMGGTVESLNVSVATGITLFEARRQRR 250


>UniRef50_A1AWI4 RNA methyltransferase, TrmH family, group 3 n=3
           Tax=Gammaproteobacteria RepID=A1AWI4_RUTMC
          Length = 247

 Score =  191 bits (486), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 45/149 (30%), Positives = 77/149 (51%), Gaps = 3/149 (2%)

Query: 19  DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTH 76
              + ++ +  P N+ A +R+A+A GVH V     GS      +   +AG+ + +++   
Sbjct: 98  GFILILDSIQDPRNLGACLRSANAAGVHCVVINKNGSAPINSLVHKTSAGALNQLKIFQV 157

Query: 77  RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQD 136
             +   +  L+ + + ++    S N +   +ID T P  I+MG E +G+ +      DQ 
Sbjct: 158 TNLSRTIKALQQKNIWVIGLDGSVN-ISIYQIDLTIPNAIIMGAEGSGLRRLTKQSCDQL 216

Query: 137 IIIPMIGMVQSLNVSVASALILYEAQRQR 165
             IPM G V+SLNVSVA+ + L+E  RQR
Sbjct: 217 AKIPMQGKVESLNVSVATGVTLFEVNRQR 245


>UniRef50_A2C1X9 RNA methyltransferase TrmH, group 3 n=6 Tax=Cyanobacteria
           RepID=A2C1X9_PROM1
          Length = 442

 Score =  191 bits (485), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 48/185 (25%), Positives = 86/185 (46%), Gaps = 10/185 (5%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR----TMASAA 64
           I    A     L + ++ +  P N+ AIIR+A+A+G   +    P  R      ++A  A
Sbjct: 260 IDACKAFGDSSLLLALDGLTDPQNLGAIIRSAEALGAQGLIL--PQRRSAGLTGSVAKVA 317

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTG 124
           AG+   + V     +  ++  LK +G  ++     + +    EI +  P  +++G E  G
Sbjct: 318 AGALEHLPVARVVNLNRSLEKLKDEGYTVVGLA-EEGSSTLSEIKFQGPLVVVVGSEDKG 376

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ---RQNAGMYLRENSMLPEA 181
           I+     L DQ + IP+ G+  SLN SVA+++ LYE  R    R  +G       + P+ 
Sbjct: 377 ISLITRRLCDQLVRIPLKGVTTSLNASVATSIFLYEVARSKWMRSISGQDPSPRLLKPQI 436

Query: 182 EQQRL 186
             +++
Sbjct: 437 SSEKI 441


>UniRef50_Q0EVP7 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Mariprofundus
           ferrooxydans PV-1 RepID=Q0EVP7_9PROT
          Length = 247

 Score =  191 bits (485), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 47/166 (28%), Positives = 79/166 (47%), Gaps = 4/166 (2%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR---MRTMAS 62
           +    + +      + + ++QV  PHN+ A +RTA+A G   V  +   +       +A 
Sbjct: 83  FEAWLKTVDMETAPMVLLLDQVTDPHNLGACVRTAEAAGCAAVIVLKDHAADVHSPVVAK 142

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
           AA G+ S + V     +   +  L+ QG   +     +  +   +   +  T ++MG E 
Sbjct: 143 AACGALSRLPVLRVINMKRCIEQLQQQGFWTVGLA-GEAELSIYDAKLSGATAVVMGSED 201

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
            G+ +      DQ I IPM G+V+SLNVSVA+ + L+E  RQR  A
Sbjct: 202 KGVRRLVRETCDQLIHIPMPGVVESLNVSVATGVALFEINRQRVTA 247


>UniRef50_A7B5E9 Putative uncharacterized protein n=7 Tax=Bacteria
           RepID=A7B5E9_RUMGN
          Length = 275

 Score =  190 bits (484), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 42/151 (27%), Positives = 72/151 (47%), Gaps = 4/151 (2%)

Query: 18  PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAGSNSWVQVKT 75
           P L   ++ +  P N+  I RTA+A GV  +        +       +  G+   +    
Sbjct: 126 PHLM-ILDNLQDPGNLGTIFRTAEAAGVTGIIMSRDCVDIYNPKTIRSTMGALYRMPFVY 184

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
              + + +  LK + ++  A HL      + + DY + T  L+G E  G+ +E    AD 
Sbjct: 185 VEDLRETIHTLKEKNIKSYAAHLDGKNT-YDKEDYRQGTAFLIGNEGNGLREEIAQCADT 243

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            I IPM G V+SLN +VA+ ++++E  RQR+
Sbjct: 244 WIRIPMCGQVESLNAAVAATVLMFEVSRQRR 274


>UniRef50_Q1JXE5 RNA methyltransferase TrmH, group 3 n=1 Tax=Desulfuromonas
           acetoxidans DSM 684 RepID=Q1JXE5_DESAC
          Length = 244

 Score =  190 bits (484), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 48/164 (29%), Positives = 76/164 (46%), Gaps = 5/164 (3%)

Query: 4   TRYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT-- 59
             +  + ++LA+  +     + ++ +  PHN  A+IR+A A G   V      S   T  
Sbjct: 75  QDFVSLAQLLAQSSQSERFFLILDGITDPHNFGALIRSAAAAGCQGVIFAKDRSCPVTGI 134

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
           +   AAG+  +VQ+     +G A+  LK  G+ +      +      E   + P  ++ G
Sbjct: 135 VEKTAAGTLGYVQLCQVTNLGRAIEELKKAGVWVYGLAGEEG-QSLFEAPLSAPIALVAG 193

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
            E  GI      L D  I IPM G V+SLNVSVA+ + L+E  R
Sbjct: 194 SEGRGIRPLIRKLCDGLIAIPMPGRVESLNVSVATGIALFEVVR 237


>UniRef50_B8I1W5 RNA methyltransferase, TrmH family, group 3 n=5 Tax=Clostridium
           RepID=B8I1W5_CLOCE
          Length = 269

 Score =  190 bits (483), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 46/172 (26%), Positives = 82/172 (47%), Gaps = 12/172 (6%)

Query: 7   ARICEMLARRQPDL---------TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM 57
             I  ++ + +             V ++ +  P N   IIRTADA G+  V        +
Sbjct: 95  QGILAVIKKNKYSFDKVITEGSSVVILDCLQDPGNAGTIIRTADAAGISAVLMSKGCVDL 154

Query: 58  R--TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
               +  +  GS   + +     I + +  LK    +++A+HLS    ++ + D T  + 
Sbjct: 155 YSPKVLRSTMGSVFHIPIFEGLNITEIIRVLKQNDYKVIASHLSGK-NNYFQEDLTGRSA 213

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           I++G E  GI+ E   +AD  + IPM G  +SLN SVA+++++YE  RQ+ +
Sbjct: 214 IIVGNEANGISDETAYMADSLVKIPMPGKAESLNASVAASVMIYEIVRQKSH 265


>UniRef50_B5YID5 RNA methyltransferase, TrmH family, group 3 n=1
           Tax=Thermodesulfovibrio yellowstonii DSM 11347
           RepID=B5YID5_THEYD
          Length = 248

 Score =  190 bits (483), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 59/172 (34%), Positives = 87/172 (50%), Gaps = 7/172 (4%)

Query: 1   MNPTRYARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P +   + E L     + +P   + ++ V  P N  +I R ADA GVH +      S 
Sbjct: 76  IKPKKTITLDEALKISFKKNEPAFFLILDLVEDPQNFGSICRIADAAGVHAIIYQKKRSV 135

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
             + ++  A+AG+   V +     I  A+  LK   + I         V F E D+T+P 
Sbjct: 136 GIVPSVWKASAGAVWHVNLVEINNIKYAIKTLKEHNITIYGAEAQAKDV-FWESDFTQPL 194

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            +++G E  GI Q  +AL D+ I IPM G + SLNVSVASALI +E  RQR+
Sbjct: 195 GLIVGSEGKGIRQTVIALCDKVIKIPMRGTINSLNVSVASALITFEVLRQRK 246


>UniRef50_Q31FJ2 RNA methyltransferase TrmH, group 3 n=1 Tax=Thiomicrospira
           crunogena XCL-2 RepID=Q31FJ2_THICR
          Length = 244

 Score =  189 bits (481), Expect = 6e-47,   Method: Composition-based stats.
 Identities = 47/160 (29%), Positives = 77/160 (48%), Gaps = 3/160 (1%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAA 65
            +  +L      L + +++V  PHN+ AI+RTADA GV  V      S     T+   A 
Sbjct: 83  DLKALLEAESNPLFLFLDEVQDPHNLGAILRTADATGVTAVVIPKHNSVGVNATVRKVAC 142

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G+   V+V     +   +  L+  G+ +      +      ++D+     ++MG E +G+
Sbjct: 143 GAAETVKVVVVSNLVRTIKELQQAGLWVTGLA-GETNTTLYQLDFKGAVGLVMGAEGSGL 201

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            +      D    IPM G ++SLNVSVA+ ++LYE  RQR
Sbjct: 202 RKLTRETCDHLAAIPMAGSIESLNVSVATGVVLYEVYRQR 241


>UniRef50_A4GI27 rRNA methyltransferase n=1 Tax=uncultured marine bacterium
           EB0_41B09 RepID=A4GI27_9BACT
          Length = 246

 Score =  189 bits (481), Expect = 6e-47,   Method: Composition-based stats.
 Identities = 46/165 (27%), Positives = 77/165 (46%), Gaps = 5/165 (3%)

Query: 5   RYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTM 60
           +Y  + +++     +P L + ++ V  P N+ A  R ADA+GV  +      +     T+
Sbjct: 82  KYVTVEDIIEENYDKPLLFLILDGVVDPQNLGACFRVADAMGVDALICPKDNAVGLNATV 141

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A G    V       +   + +LK   + +  T  + N    ++ ++     ++MG 
Sbjct: 142 RKVACGGAESVPFVVVTNLARTIRYLKNSNVFVYGTDDNAN-KSLQKTNFKGSIALVMGS 200

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           E  G+ +    L D    IPM+G V+SLNVSVAS + LYE  RQR
Sbjct: 201 EGKGMRRLTNELCDDIFSIPMMGQVESLNVSVASGICLYEINRQR 245


>UniRef50_D2RLA3 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Acidaminococcus
           RepID=D2RLA3_ACIFE
          Length = 260

 Score =  189 bits (480), Expect = 8e-47,   Method: Composition-based stats.
 Identities = 47/169 (27%), Positives = 83/169 (49%), Gaps = 9/169 (5%)

Query: 3   PTRYARICEMLARR------QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           P   A + E+          +  + + ++++  P N+  +IRTADA+G   V  +   + 
Sbjct: 89  PQSVAALVELRREELAAFAPERGMVLVLDRIRDPGNLGTLIRTADALGAAGVVLLENTAD 148

Query: 57  MRT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
           +    +  +  GS   + V T    G+     +  G  + AT L + A D   + +   T
Sbjct: 149 LYNPKVVRSTMGSLFHLPVFTGVKTGELEEWCRQHGYALWATAL-EGAEDMTRLTWPEKT 207

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
            +++G E  G++ E LA ADQ + IPM G  +SLNV+VA  ++++EA R
Sbjct: 208 ALVLGSEAEGVSPEILAAADQKVKIPMAGHAESLNVAVAGGIVMFEAAR 256


>UniRef50_Q1NS81 RNA methyltransferase TrmH, group 3 n=3 Tax=Deltaproteobacteria
           RepID=Q1NS81_9DELT
          Length = 302

 Score =  189 bits (480), Expect = 8e-47,   Method: Composition-based stats.
 Identities = 47/152 (30%), Positives = 79/152 (51%), Gaps = 3/152 (1%)

Query: 18  PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAAGSNSWVQVKT 75
           P L + ++ +  PHN+ A++R+A A GV  V      S     T+  AAAG+ + + +  
Sbjct: 145 PPLLLVLDSLQDPHNLGAVLRSAAAFGVDGVILPKDRSAPLSGTVLKAAAGTAALLDICR 204

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
              +  A+  LK  G  I      + + +  E D+T PTC+++G E+ GI        D 
Sbjct: 205 TTNLAGALGTLKKHGFWIYGAS-GEASGNLYETDFTGPTCLVLGNEQKGIRPLLKKHCDF 263

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
            + IP+   V+SLNVSVA+ ++L E +R++  
Sbjct: 264 LLAIPLAAGVESLNVSVAAGIMLAEIRRRQHF 295


>UniRef50_A1APM1 RNA methyltransferase, TrmH family, group 3 n=8
           Tax=Desulfuromonadales RepID=A1APM1_PELPD
          Length = 251

 Score =  189 bits (480), Expect = 8e-47,   Method: Composition-based stats.
 Identities = 44/169 (26%), Positives = 73/169 (43%), Gaps = 7/169 (4%)

Query: 1   MNPTRYARICEMLARRQPD----LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P  YA + +++     +      + ++ +  PHN+ A+IRTA   G   V      + 
Sbjct: 74  VAPFSYADLDDLIEAGDREDAAGFLLVLDGIQDPHNLGALIRTAACAGASGVVIPRDRAC 133

Query: 57  MRTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
             T A   A+AG+   + V     I  ++  LK  G  +       +A    E+ ++   
Sbjct: 134 AITPAAEKASAGAVETITVAQVTNIAQSLEKLKRSGYWVYGLSGEADA-SLYEVAFSGKI 192

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
            +++G E  GI        D  + IP+ G V SLN SVA  + LYE  R
Sbjct: 193 ALVIGGEGEGIRPLVRKQCDALVSIPLYGGVGSLNASVAGGIALYEVAR 241


>UniRef50_A5IXH9 tRNA/rRNA methyltransferase n=1 Tax=Mycoplasma agalactiae PG2
           RepID=A5IXH9_MYCAP
          Length = 233

 Score =  189 bits (480), Expect = 9e-47,   Method: Composition-based stats.
 Identities = 49/168 (29%), Positives = 88/168 (52%), Gaps = 7/168 (4%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR---- 56
           +    Y  I +++ +  P   + ++ +H PHN  AIIRTA+A G+   H + P  R    
Sbjct: 67  LKDFNYYEI-DVIKKDNPKTVLILDHIHDPHNFGAIIRTANAAGIK--HIIIPKDRSTDV 123

Query: 57  MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
             T+   ++G    V++     I  ++  LK  G  I ++ L +NAV + ++ Y     +
Sbjct: 124 TSTVLKVSSGGFVGVKIIKVSNIASSIEKLKKWGFWIYSSLLDENAVPYNKVQYAGNCAL 183

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           ++G E+ GI++  +   D  + IP  G VQS+NVSVA+ ++L+E   +
Sbjct: 184 VVGNEEKGISKPVVNATDVKVYIPQFGTVQSMNVSVATGILLFELVNR 231


>UniRef50_A3HSD9 SpoU protein (SpoU) n=1 Tax=Algoriphagus sp. PR1 RepID=A3HSD9_9SPHI
          Length = 234

 Score =  188 bits (479), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 55/205 (26%), Positives = 93/205 (45%), Gaps = 11/205 (5%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSN 68
           + ++LA+R    TV +E ++KPHN SA++RT D  G+ +VH +      +       G++
Sbjct: 29  MEKVLAQRTRHFTVVLENIYKPHNASAVLRTCDCFGIQDVHIIEKTREYKVNPFVTRGAS 88

Query: 69  SWVQVKTH-------RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
            W+ +  +         + +  + LK  G +I  T         +++D      ++ G E
Sbjct: 89  QWLTLHKYFQPEEPENAVINCFSSLKSNGFKIYGTSPDPQTRPIQDLDPNEKIALVFGNE 148

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEA 181
             GI+ E    AD  + IPM G  +S N+SVA++L L       Q A  Y+  +  L E 
Sbjct: 149 HEGISNEVKNAADGLVHIPMRGFTESFNISVAASLFLQNLV---QKASDYVIPDYNLTEV 205

Query: 182 EQQRLLFEGGYPVLAKVAKRKGLPY 206
           E+Q L     Y  + K +      Y
Sbjct: 206 EKQELRLTW-YRSIVKNSDIHEKKY 229


>UniRef50_Q6FF50 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=19
           Tax=Moraxellaceae RepID=RLMB_ACIAD
          Length = 248

 Score =  188 bits (479), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 55/162 (33%), Positives = 84/162 (51%), Gaps = 3/162 (1%)

Query: 7   ARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAA 64
             + ++L      L + ++QV  PHN+ A IRTA A+G+  V      S     T    A
Sbjct: 85  KDLDQLLQNNDQALLLALDQVTDPHNLGACIRTAAAMGIAAVIVPRDRSASLTPTARKVA 144

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGM-QILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           AG    V+      +   +AH+K     +++ T L + A+  ++ D++    I+MG E T
Sbjct: 145 AGGAEKVKFIQVTNLARTLAHIKAHFFVKVVGTMLDEKALPIQKYDFSGNVAIVMGAEDT 204

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           G+     +  DQ + IPM G +QSLNVSVA+ + LYEA RQR
Sbjct: 205 GLRPITQSQCDQTVYIPMSGNLQSLNVSVAAGMALYEACRQR 246


>UniRef50_B1X411 tRNA/rRNA methyltransferase (SpoU):RNA methyltransferase TrmH n=1
           Tax=Paulinella chromatophora RepID=B1X411_PAUCH
          Length = 526

 Score =  188 bits (478), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 51/160 (31%), Positives = 80/160 (50%), Gaps = 7/160 (4%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR----TMASAA 64
           I +     +  L + +E +  PHN+ AI+R+A+A+G H +    P  R      ++A  A
Sbjct: 274 IEDCCHLGENPLLMAVEGLTDPHNLGAIVRSAEALGAHGLIL--PQRRNAGLTGSVAKVA 331

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTG 124
           AG+   + V     +  ++  LK +G +I+    ++  V   E D   P  I+ G E  G
Sbjct: 332 AGALEHLPVARVVNLNRSLDILKDKGYRIVGLA-TEGDVSLTEADLNGPLVIVTGSEGNG 390

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           ++       DQ I IP+ G   SLN SVASAL+LYE  R+
Sbjct: 391 LSLLTRRYCDQLIRIPLRGATPSLNASVASALMLYEVARR 430


>UniRef50_Q7P601 23S rRNA methyltransferase n=10 Tax=Fusobacterium
           RepID=Q7P601_FUSNV
          Length = 234

 Score =  187 bits (477), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 40/156 (25%), Positives = 75/156 (48%), Gaps = 3/156 (1%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMAS 62
            +    E LA +   L + ++++  P N  AIIR+A+   V  +      S     T+  
Sbjct: 74  DFDEAYEELAEKDKSLVLILDEIQDPRNFGAIIRSAEVFKVDLIIIPERNSVRINETVVK 133

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
            + G+  +V +     + D +  LK     +      + ++++ E +Y+    +++G E 
Sbjct: 134 TSTGAIEYVNISKVTNLSDTINKLKKLDYWVYGAA-GEASINYNEENYSNKIILVLGNEG 192

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALIL 158
           +GI ++     D+ I IPM G + SLNVSVAS ++L
Sbjct: 193 SGIRKKVREHCDKLIKIPMYGQINSLNVSVASGILL 228


>UniRef50_C0Z9E4 Putative RNA methyltransferase n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0Z9E4_BREBN
          Length = 271

 Score =  187 bits (477), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 46/160 (28%), Positives = 86/160 (53%), Gaps = 3/160 (1%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAG 66
           + +    +   L + ++++  P N+  I+RTA+A  +  V        +    +  A  G
Sbjct: 113 VDQKREEQGSLLLLFLDEIQDPGNLGTILRTAEAAAIDGVVLGSGSVDIYNGKVVRATMG 172

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           +   + V T +++ D     K +G ++L + L  N+V + E DY   T +++G E  G++
Sbjct: 173 ALFRIPVFT-QSLVDTADEWKAKGGRVLISSLEQNSVSYDEADYAGLTALVIGNEGRGVS 231

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           +E  A ADQ + IP+ G  +SLN +VA+ + +YEAQR+R+
Sbjct: 232 KEMFAKADQFVHIPLYGGAESLNAAVAAGIFVYEAQRKRR 271


>UniRef50_C9KPX8 RNA methyltransferase, TrmH family n=1 Tax=Mitsuokella multacida
           DSM 20544 RepID=C9KPX8_9FIRM
          Length = 271

 Score =  187 bits (477), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 58/168 (34%), Positives = 83/168 (49%), Gaps = 5/168 (2%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR--TM 60
           P     + +  AR+   L V ++ V  P N   IIRTADAVG   V        +     
Sbjct: 107 PQMAEHLQQAAARK--PLLVVLDGVQDPGNAGTIIRTADAVGADGVILTKGSVDVFSDKT 164

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
             A  GS   + V T  +  +     +  G Q+LAT L + A     +D+ + + I  G 
Sbjct: 165 VRATMGSLFHLPVVTDVSAEEVATFAQAAGCQLLATALDEQAKPHFAVDFGKGSLIAFGN 224

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           E  G+++E LA A + + IPM G  +SLNV V+SA++LYEA RQR  A
Sbjct: 225 EGGGVSEELLAAA-EKVYIPMYGEAESLNVGVSSAVVLYEAVRQRHFA 271


>UniRef50_B2S257 Possible rRNA methylase n=3 Tax=Treponema RepID=B2S257_TREPS
          Length = 292

 Score =  187 bits (476), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 50/171 (29%), Positives = 80/171 (46%), Gaps = 4/171 (2%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAG 66
           +   LA     L + ++ +  PHNV AI+R+AD   V  V            T+   +AG
Sbjct: 121 LLHALATHTHALVLVLDAITDPHNVGAIVRSADQFSVDAVLLPHHHGAGGTETITRVSAG 180

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           + +WV +   R +      LK  G  +    ++  A+  R   +   T +++G E  G++
Sbjct: 181 AVAWVPLVRVRNLVRTAGILKRSGFWLYGADVAGEAIGART--FPPKTALVLGNEGHGVS 238

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSM 177
                  D  I IP  G V SLNVSVA+ ++LYE +R +Q+     R+N M
Sbjct: 239 PLLRTHCDALISIPTQGNVDSLNVSVAAGILLYEIRRSQQSPYSVQRQNEM 289


>UniRef50_C6CVT7 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Bacillales
           RepID=C6CVT7_PAESJ
          Length = 264

 Score =  187 bits (475), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 51/175 (29%), Positives = 83/175 (47%), Gaps = 10/175 (5%)

Query: 2   NPTRYARICEMLAR------RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS 55
            P     + E L R      R   L V ++ V  P NV  IIR+ADAVG   V       
Sbjct: 92  TPPPVFAVLEKLKRDDTALFRNNSLVVVLDGVRDPGNVGTIIRSADAVGADAVVLGKGSV 151

Query: 56  RMRTMASAA--AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
            +    +     GS   + +     + + +   + +G++++ T L      +   D+T  
Sbjct: 152 DLYNPKTVRSTMGSLFHLPIIE-ADLAELLPEAQSKGIKLVGTSLQATHTCYT-YDWTAG 209

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           T +LMG E  G++       D+ +IIPM G  +SLNV++A+ ++LYEA RQR+ +
Sbjct: 210 TWLLMGNESEGLSDAVRLAVDESVIIPMQGEAESLNVAMAATVLLYEAVRQRKYS 264


>UniRef50_A6L4B5 tRNA/rRNA methyltransferase n=16 Tax=Bacteroidetes
           RepID=A6L4B5_BACV8
          Length = 255

 Score =  186 bits (474), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 47/156 (30%), Positives = 80/156 (51%), Gaps = 3/156 (1%)

Query: 12  MLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSNS 69
           +    +  L V ++ +    N  AI RT +  G   +      S          +AG+  
Sbjct: 90  LFEEGKTPLFVMLDGITDVRNFGAIARTCECAGADAIIIPSKNSVSVNADAMKTSAGALH 149

Query: 70  WVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEA 129
            + V   + + + + +LK  G +I+A        D+ + +Y  P CI+MG E TG+  E 
Sbjct: 150 TLPVCREQNLTNTIKYLKDCGFKIVAAT-EKGDYDYTKANYKDPVCIIMGAEDTGVPYEH 208

Query: 130 LALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           L+L D+ I IP++G ++SLNVSVA+ +++YEA +QR
Sbjct: 209 LSLCDEWIKIPLMGKIESLNVSVAAGILIYEAVKQR 244


>UniRef50_Q31LC0 RNA methyltransferase TrmH, group 3 n=22 Tax=Bacteria
           RepID=Q31LC0_SYNE7
          Length = 519

 Score =  186 bits (474), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 51/182 (28%), Positives = 82/182 (45%), Gaps = 11/182 (6%)

Query: 1   MNPTRYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P  Y  + +++A+ +      + V  + +  PHN+ AIIRTA+A+G H +  V P  R
Sbjct: 313 VAPYPYQELSDLIAQAKAATTDPVIVVADGITDPHNLGAIIRTAEALGAHGL--VIPQRR 370

Query: 57  MRTMASAAAGS----NSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR 112
              + +A A           V     +  A+  LK  G  I      +      E  ++ 
Sbjct: 371 AVGVTAAVAKVAAGALESFPVARVVNLNRALEELKDAGFWIYGAA-GEAKQSIHETSFSG 429

Query: 113 PTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYL 172
           P  +++G E  G++       D  I IP+ G   SLN SVA+ ++LYE  RQRQ    +L
Sbjct: 430 PVVLVVGSEDEGLSLLTRERCDHLISIPLRGKTNSLNASVAAGMVLYEVSRQRQQLTHHL 489

Query: 173 RE 174
             
Sbjct: 490 EG 491


>UniRef50_B2V596 RNA methyltransferase, TrmH family n=7 Tax=Clostridium
           RepID=B2V596_CLOBA
          Length = 262

 Score =  186 bits (474), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 49/169 (28%), Positives = 83/169 (49%), Gaps = 6/169 (3%)

Query: 2   NPTRYARICEMLARR---QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
           NP     I +M  ++   Q D  +  ++V  P N+  IIRTA A GV+ +        + 
Sbjct: 91  NPQGIIAIVKMNNKKLDFQGDFYLFCDKVQDPGNLGTIIRTAHAAGVNGIVLSKGTVDIY 150

Query: 59  T--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
                 +  GS  ++ +         +  LK  G  ++ T L +++ DF + D      +
Sbjct: 151 NEKTIRSTMGSLFYMPIYYDDDEFSLIKSLKKDGFTLIVTSL-ESSKDFFKEDLKGKIIL 209

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            +G E  G++ E L LAD+ + IPM G  +SLNV++A+++I+YE  RQ 
Sbjct: 210 TVGNEGNGVSNEVLDLADRRVKIPMPGGAESLNVAIATSIIIYEKVRQN 258


>UniRef50_B0K3L2 tRNA/rRNA methyltransferase (SpoU) n=11 Tax=Thermoanaerobacterales
           RepID=B0K3L2_THEPX
          Length = 254

 Score =  186 bits (474), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 45/152 (29%), Positives = 76/152 (50%), Gaps = 7/152 (4%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQV 73
           +   + +  + +  P N+  IIRTADA G   +  +     +    +  A+ GS   + V
Sbjct: 103 KDKGIYIIADNIQDPGNLGTIIRTADAFGASAIFTINNCVDVFNPKVLRASMGSIFHIPV 162

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALA 133
               T    +  LK +G+++ ATHL    +   E + +     ++G E  G++   + L 
Sbjct: 163 IV--TASQILLKLKQRGIKVFATHLKARKL-VHECNISDKVAFVLGNEAKGVS--VVDLV 217

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           D  + IPM G  +SLNVS+A+ + LYE+QRQR
Sbjct: 218 DDFVKIPMTGEAESLNVSIAAGIFLYESQRQR 249


>UniRef50_A9S3U1 Predicted protein (Fragment) n=2 Tax=Physcomitrella patens subsp.
           patens RepID=A9S3U1_PHYPA
          Length = 241

 Score =  186 bits (473), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 55/193 (28%), Positives = 98/193 (50%), Gaps = 5/193 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP--GSRMR 58
           +   R  RI E++A R   + + +E +    NVSA+ R+ADA+G   VH +      R +
Sbjct: 34  LGDERKQRIEEVVANRTYSICIAVEGLLDLGNVSAVCRSADALGFQSVHVISNETKKRYK 93

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
                + G+  W+  +      D +  L+ +G +I  TH++ + V   ++D+T PT +  
Sbjct: 94  KNRKVSMGTEKWLDAELWSNTSDCIDTLRQRGYRIAVTHIAPDTVSIYDMDWTIPTAVFF 153

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSML 178
           G E  G ++EA+  +D    IPM GMV+S N+SVA+ +I++ A R R    +    +  +
Sbjct: 154 GNEFMGASEEAIKQSDVRCCIPMAGMVESFNISVAAGIIMHHAARDR---IIRSGVHGDI 210

Query: 179 PEAEQQRLLFEGG 191
              +++ L  E  
Sbjct: 211 SPEDRRILEAEFC 223


>UniRef50_B8FEV3 RNA methyltransferase, TrmH family, group 3 n=1
           Tax=Desulfatibacillum alkenivorans AK-01
           RepID=B8FEV3_DESAA
          Length = 249

 Score =  186 bits (473), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 3/168 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--R 58
             P     + +     QP   + M++++ P N  A++RTA   GV+ V      S     
Sbjct: 76  FKPIALELLVKKAGGEQPLFFLLMDEINDPQNCGALMRTALCAGVNGVIMPDKRSSPLSP 135

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
            ++ A+AG+   + V     +  ++ +LK QG+         +     E D T P  +++
Sbjct: 136 AVSKASAGALEHMPVARVVNLVRSMQYLKDQGVWFFGLDARASGT-VWEADLTGPAAVVV 194

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           G E  G+        DQ + IP  G + SLN SVA AL +YE  RQR+
Sbjct: 195 GNEGKGLRPLVRKECDQLVSIPQAGPLGSLNASVAGALSMYEVMRQRR 242


>UniRef50_C2KW83 Possible RNA methyltransferase n=1 Tax=Oribacterium sinus F0268
           RepID=C2KW83_9FIRM
          Length = 260

 Score =  186 bits (473), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 43/155 (27%), Positives = 76/155 (49%), Gaps = 3/155 (1%)

Query: 14  ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAAGSNSWV 71
            + + DL + +E +  P N+  + RTA+A GV+ +             +  +  GS   +
Sbjct: 101 EKPKGDLFLILENIQDPGNLGTLFRTAEAAGVNHIFLSRNTVDPFSPKVVRSTMGSLFRL 160

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
                  +      LK  G+Q+ A  L      F+   +  P+  L G E  G+T+E   
Sbjct: 161 PFSIEEDLFFLCESLKSAGVQVFALDLDGKKTHFQAA-FQGPSAFLFGNEGNGLTKELSQ 219

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            A + ++IPM G ++SLNV+ +++++LYEA RQR+
Sbjct: 220 CATEKLLIPMEGKIESLNVATSASIVLYEAVRQRR 254


>UniRef50_Q87D65 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=49 Tax=cellular
           organisms RepID=RLMB_XYLFT
          Length = 249

 Score =  186 bits (473), Expect = 6e-46,   Method: Composition-based stats.
 Identities = 42/148 (28%), Positives = 69/148 (46%), Gaps = 3/148 (2%)

Query: 20  LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSNSWVQVKTHR 77
           L + ++ V  PHN+ A +R+A A GV  V      S     T+   ++G+   + V    
Sbjct: 100 LLLVLDGVQDPHNLGACLRSAAAAGVTAVIIPKDKSVGINATVRKTSSGAADRLPVIAVV 159

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            +  ++  L+ Q + I      +       +D      +++G E  G+ +      D   
Sbjct: 160 NLARSLRELQKQDVWIYGLA-GEVETSLYALDLRGNVALVLGGEADGLRRLTREHCDVLA 218

Query: 138 IIPMIGMVQSLNVSVASALILYEAQRQR 165
            IPM G V+SLNVSVA+ + L+EA RQR
Sbjct: 219 RIPMPGEVESLNVSVAAGVTLFEAVRQR 246


>UniRef50_D2REE3 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Archaeoglobus
           profundus DSM 5631 RepID=D2REE3_ARCPR
          Length = 232

 Score =  186 bits (472), Expect = 7e-46,   Method: Composition-based stats.
 Identities = 44/170 (25%), Positives = 82/170 (48%), Gaps = 10/170 (5%)

Query: 1   MNPTRYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR-- 56
           ++P  Y  +  ++ +  R+    + ++ V  P N+ AI+R+A+  G   V  V P  R  
Sbjct: 63  ISPIEYKEVDTIIDKCIREGSFILFLDSVEDPQNMGAIMRSAEFFGCAGV--VIPKRRCV 120

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T+A  +AG+   + +     + + +  LK  G+ ++   L       R +D + P 
Sbjct: 121 QVNETVAKVSAGAVFHLDIARVENLANILKKLKKFGITVVGADLDGE--PLRNVDLSPPL 178

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            I++G E  G+++      D    I   G + SLN+SVA A+I+YE +R+
Sbjct: 179 AIVVGGEDKGLSKPVKKQCDFIAKIEGYGKINSLNLSVAGAIIMYEFRRR 228


>UniRef50_D0GJ12 RNA methyltransferase, TrmH family, group 3 n=3
           Tax=Fusobacteriaceae RepID=D0GJ12_9FUSO
          Length = 244

 Score =  184 bits (469), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 40/163 (24%), Positives = 72/163 (44%), Gaps = 6/163 (3%)

Query: 6   YARICEMLAR---RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG--SRMRTM 60
           Y  + E   +   +   + V ++Q+  P N  AIIR+A+  GV  +            T+
Sbjct: 83  YLELTEFFEKVLAKDKSIVVILDQIQDPRNFGAIIRSAECFGVDGIVIQDRNNVKVTETV 142

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
             ++ G+   V +     I D +   K  G ++     +D    + E  Y +  C+++G 
Sbjct: 143 VKSSTGAIEHVDIIKVTNISDTIDKFKKYGYKVYGAE-ADGENLYYEESYPKKVCLVLGS 201

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           E  G+ ++     D+ + I + G   SLNVSVA  +IL E  +
Sbjct: 202 EGNGMRKKVREHCDKTLKIHLKGQTNSLNVSVAGGIILAEMSK 244


>UniRef50_C7G6D1 RNA methyltransferase, TrmH family n=5 Tax=Clostridiales
           RepID=C7G6D1_9FIRM
          Length = 281

 Score =  184 bits (469), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 46/162 (28%), Positives = 81/162 (50%), Gaps = 4/162 (2%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAA 65
            + E++   Q  L + +E +  P N+  ++RT +  G+  V        +       +  
Sbjct: 122 ALEELIKGEQTHL-LILESIQDPGNLGTMVRTGEGAGITGVIMNQTTVDLFNPKTIRSTM 180

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           GS   V     + +   ++ LK Q + + A HL    + + E DY + T  L+G E  G+
Sbjct: 181 GSIYRVPFFITKDLAGTISSLKEQQVNVYAAHL-KGTLSYDEPDYKKKTAFLIGNEGNGL 239

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           + E   LAD  I IPM G V+SLN +++++L++YE  RQR++
Sbjct: 240 SDEIADLADTYIKIPMQGQVESLNAAISASLLMYETGRQRRH 281


>UniRef50_Q3AXD9 RNA methyltransferase TrmH, group 3 n=19 Tax=Bacteria
           RepID=Q3AXD9_SYNS9
          Length = 652

 Score =  184 bits (469), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 44/153 (28%), Positives = 79/153 (51%), Gaps = 7/153 (4%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR----TMASAAAGSNSWVQ 72
           +P L + ++ +  PHN+ A++R+A+A+G H +  V P  R      + A  AAG+   + 
Sbjct: 381 EPPLLLALDGITDPHNLGAVVRSAEAMGAHGL--VLPQRRSAGLTGSAAKVAAGAMEHLP 438

Query: 73  VKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALAL 132
           V     +  ++  LK  G +++    ++  V   ++D   P  ++ G E  G++      
Sbjct: 439 VARVVNLNRSLEKLKDSGYRVIGLA-AEGDVTLMDVDLEGPLVLVTGSEDQGLSLLTRRH 497

Query: 133 ADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            DQ + IP+ G+  SLN SVA+AL +YE  R+ 
Sbjct: 498 CDQLVRIPLRGITPSLNASVATALCVYEVARRN 530


>UniRef50_A7HIF7 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Anaeromyxobacter
           RepID=A7HIF7_ANADF
          Length = 239

 Score =  184 bits (468), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 68/206 (33%), Positives = 108/206 (52%), Gaps = 1/206 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW-PGSRMRT 59
           + P R ARI  ++A R   LTV ME    P NV+A++RT +A G+ E+H +  P      
Sbjct: 26  LVPERRARIDAVVANRTRTLTVVMEAFCDPQNVNAVLRTCEAFGIQELHVIEGPMKPYDR 85

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
               +  ++ WV V+   + G+ +AHLK +G  I ATHL + A     + +     ++ G
Sbjct: 86  NKKISQNADKWVDVRRWSSTGECLAHLKAEGFAIYATHLGEGARTLDALSFAGKVALVFG 145

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E  G++ EA+AL+D   +IPM G VQSLNVSVA+A+ + +A  +R        + S L 
Sbjct: 146 NEHRGVSDEAVALSDAVYVIPMHGFVQSLNVSVAAAISIAKAVERRAAERGRHGDLSELE 205

Query: 180 EAEQQRLLFEGGYPVLAKVAKRKGLP 205
            A  +   +       A++AK + + 
Sbjct: 206 AAALRERFYVLAVKQRARIAKAERVD 231


>UniRef50_A5UYW3 RNA methyltransferase, TrmH family, group 3 n=4 Tax=Chloroflexi
           (class) RepID=A5UYW3_ROSS1
          Length = 252

 Score =  184 bits (467), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 44/174 (25%), Positives = 86/174 (49%), Gaps = 10/174 (5%)

Query: 2   NPTRYARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           +   Y  + + LA    R +P   + ++ +  P NV  ++RTA+ VGVH V  V PG R 
Sbjct: 76  SDYPYVDLNDCLALAEERGEPAFLLLLDHIQDPQNVGTLLRTAEVVGVHGV--VIPGRRA 133

Query: 57  ---MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
                 + + ++G+   ++V     +   +  ++  G+ ++     + A ++  +D   P
Sbjct: 134 AEVTPAVVNTSSGAVEHLRVAVVTNLAATIEQIQHAGVWVVGVEDDERAYEYDRVDLDLP 193

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
             +++G E  G+ +      D  + +PM G + SLNV+VA +++LY A R R+ 
Sbjct: 194 LALVLGAEGPGLARLTRERCDFLVRLPMRGQIASLNVAVAGSIVLYHAWRVREQ 247


>UniRef50_C6X1H8 rRNA methylase n=4 Tax=Bacteroidetes RepID=C6X1H8_FLAB3
          Length = 265

 Score =  184 bits (467), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 51/171 (29%), Positives = 90/171 (52%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++   +  I ++L       +    + ++++    N  AI RTA+ VGVH +     G+ 
Sbjct: 91  ISDVPFESIQDVLPQLFEEGKTPFLLILDRLTDVRNFGAICRTAECVGVHAIILPEKGAA 150

Query: 57  M--RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
                    +AG+   +++   + +  AV  L+  G+Q+ +       +   ++D+T+P 
Sbjct: 151 PINSDAIKTSAGAIYNLRICKEKNLAHAVDFLQQSGLQVFSASEKAQKL-IYDVDFTQPC 209

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            I+MG E+TGI++E L  +D+ I +P+ G  QSLNVSVA   ILYEA RQ+
Sbjct: 210 AIVMGNEETGISKEVLHHSDEKIKLPIEGKTQSLNVSVACGAILYEAVRQK 260


>UniRef50_B0TZ81 tRNA/rRNA methyltransferase n=20 Tax=Francisella RepID=B0TZ81_FRAP2
          Length = 248

 Score =  184 bits (467), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 44/160 (27%), Positives = 72/160 (45%), Gaps = 3/160 (1%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS--RMRTMASAAA 65
            I  ++ + +    + ++ V  PHN  A IR+A + G+  +      S     T+   A 
Sbjct: 86  DIENLIPQDKNAFILILDNVQDPHNFGACIRSAHSAGIDFIIIPKDNSAPVNATVKKVAC 145

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G+    ++     +  A+  LK  G+ I+      N      ++      I+ G E +G+
Sbjct: 146 GAAEHTKIVVVTNLARAIEKLKQLGVWIIGLAGEAND-SLYSMNLADSVAIVAGAEGSGM 204

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            Q   A  D    +PM+G V SLNVSVA+ + LYE  RQR
Sbjct: 205 RQRTKASCDFLAKLPMLGEVSSLNVSVATGIALYETVRQR 244


>UniRef50_D1CD69 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Thermobaculum
           terrenum ATCC BAA-798 RepID=D1CD69_THET1
          Length = 264

 Score =  184 bits (467), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 39/167 (23%), Positives = 77/167 (46%), Gaps = 6/167 (3%)

Query: 2   NPTRYARICEMLAR---RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR-- 56
           +   Y+ I ++LA    R  D  + ++ +  P N   ++RTA+  G+  V      S   
Sbjct: 94  SEFSYSSIEDLLASGELRGKD-ILMLDSLQDPQNFGTLLRTAEVFGIGAVIIPEHRSVEV 152

Query: 57  MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
              + +A++G+   + +     +    + LK  G  +L     +++    ++D   P C+
Sbjct: 153 TPAVVNASSGATEHLNISKVTNLARTASKLKEYGYWVLGLEYDESSSVIWDVDLRIPICL 212

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           ++G E +GI +      D  + IP  G + SLN +VA ++ LYE  +
Sbjct: 213 VVGSEGSGIRELVRKRCDLLVKIPQAGRIGSLNAAVAGSIALYEIYK 259


>UniRef50_C2FZ75 Possible tRNA/rRNA methyltransferase n=2 Tax=Sphingobacterium
           spiritivorum RepID=C2FZ75_9SPHI
          Length = 259

 Score =  184 bits (467), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 55/173 (31%), Positives = 93/173 (53%), Gaps = 9/173 (5%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++P  Y +I +++     + +  L + ++ V    N+ AI RTA+  GVH +     GS 
Sbjct: 86  ISPITYQKIEDLIPEIYEKGETPLILMLDGVTDVRNLGAIARTAECSGVHAIIVPKKGSA 145

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQ-ILATHLSDNAVDFREIDYTRP 113
                    +AG+   + V  H  +G     L   G+Q +++T  ++ +     +DYT P
Sbjct: 146 EINPDAIKTSAGALYKIPVCRHDNLGKVGKFLIDSGIQLVVSTEKTEES--IYSVDYTAP 203

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           TCI+MG E  G++ + + ++D    IPM G + SLNVSV++ ++LYEA RQRQ
Sbjct: 204 TCIIMGAEDVGVSDDLIRISDHLAKIPMFGEIGSLNVSVSAGVVLYEAIRQRQ 256


>UniRef50_A8STN2 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A8STN2_9FIRM
          Length = 272

 Score =  183 bits (466), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 38/150 (25%), Positives = 70/150 (46%), Gaps = 4/150 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTHRT 78
            + ++ +  P N+  I R+A+A G+  V             +  +  G+   V       
Sbjct: 122 YLILDTIQDPGNMGTIFRSAEAAGITGVIIGPGSCDPYNPKVVRSTMGAIFRVPFVQSDD 181

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           +   +  LK +G+ I   HL        + ++      L+G E  G+++     AD+ + 
Sbjct: 182 LIYTIDALKRKGVLIYGAHLDGEE--LYDTEFPDKIAFLIGNEGNGLSKAVSDTADRLLR 239

Query: 139 IPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           IPM G V+SLN ++++ L+ YEA RQR++A
Sbjct: 240 IPMEGKVESLNAAISATLLSYEAMRQRRSA 269


>UniRef50_B1C951 Putative uncharacterized protein n=1 Tax=Anaerofustis
           stercorihominis DSM 17244 RepID=B1C951_9FIRM
          Length = 242

 Score =  183 bits (466), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 41/159 (25%), Positives = 74/159 (46%), Gaps = 4/159 (2%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAAG 66
           I +M  +    L V ++ +  PHN  AIIR+A   G   V      S      M  ++AG
Sbjct: 86  IEKMNEKVTKPLVVILDNITDPHNAGAIIRSAYCAGADGVIMQTRRSASIGEGMYKSSAG 145

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           +   + +     I   +  LK +G+ ++   ++    ++ ++DY  P  +++G E  G+ 
Sbjct: 146 AIEHIDLCEVSNIAQTIDTLKKEGLFVVGLDMNGE--NYYDMDYDMPLALVVGAEGKGLG 203

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +      D    IP+     SLN SVA+ ++L+EA + R
Sbjct: 204 RLIKEKCDFISSIPLKNDFDSLNASVAAGIVLFEAVKTR 242


>UniRef50_Q1IWR8 RNA methyltransferase TrmH, group 3 n=6 Tax=Deinococci
           RepID=Q1IWR8_DEIGD
          Length = 246

 Score =  183 bits (466), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 48/159 (30%), Positives = 75/159 (47%), Gaps = 3/159 (1%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAAG 66
           +    AR +  L V ++ +  P N  AIIR+A+ +G H V      S      +   AAG
Sbjct: 78  LDRAEARGEDLLIVLLDGITDPRNFGAIIRSAEVLGAHGVVVEERRSAPLSPVVVKTAAG 137

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           + S++ V   + +   +  LK  G+ I      + A D    D +    +++G E  G+ 
Sbjct: 138 ATSYLPVAQTKNLPRLIDALKEDGVWIYGAA-GEAAQDIGRTDLSGKVALVIGAEGEGLR 196

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +      D  + IP  G VQSLN SVA+ ++LYEA R R
Sbjct: 197 RLVREKCDALVRIPTRGQVQSLNASVAAGILLYEAARAR 235


>UniRef50_UPI0001C31319 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Conexibacter
           woesei DSM 14684 RepID=UPI0001C31319
          Length = 256

 Score =  183 bits (466), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 53/170 (31%), Positives = 85/170 (50%), Gaps = 9/170 (5%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           + P RYA + E+LA   P L V ++++  P N+ AI RTA+  G   +  V P  R   +
Sbjct: 90  VAPFRYAYVDELLAVEHP-LIVALDEIQDPQNLGAIARTAECAGATGL--VIPARRSADV 146

Query: 61  A----SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP-TC 115
                 A+AG+   + +   R + D +   +G G  +      D  V +  +DY+ P   
Sbjct: 147 TPAVCKASAGAVEHLPIARARNLADFLGDARGVGAWVYGAE-GDGGVPYTGVDYSGPGVV 205

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +++G E  G+     A  D  I +P+ G + SLNVS A++ +LYE  RQR
Sbjct: 206 LVLGSEGRGLRPRVAASCDALIALPLRGRIGSLNVSAAASALLYEIVRQR 255


>UniRef50_B4U792 RNA methyltransferase, TrmH family, group 3 n=9 Tax=Aquificales
           RepID=B4U792_HYDS0
          Length = 251

 Score =  182 bits (464), Expect = 5e-45,   Method: Composition-based stats.
 Identities = 45/175 (25%), Positives = 83/175 (47%), Gaps = 10/175 (5%)

Query: 1   MNPTRYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
           ++P  Y    E+  +   +    V ++ +  P NV +I RT +  G   +  + P  R  
Sbjct: 77  LSPITYVPEEELFRKTIEEKGFFVVLDHITDPQNVGSIARTVEVFG--GIGLLIPKDRSA 134

Query: 59  T----MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
                +  +++G+   +++    +I  A+   K  G  + A        D  ++D+  P 
Sbjct: 135 PINAVVVKSSSGAIFHLKISKTPSISKAIKTFKEMGGWVYALE--KGGKDITKVDFAYPM 192

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
           CI++G E  G+++  L  +D  + IPM G V SLNVS A A+ L+E  + ++N G
Sbjct: 193 CIVLGSEGEGVSKNVLEHSDVRVSIPMKGKVTSLNVSAAGAICLWEVYKNQENTG 247


>UniRef50_D2QM84 RNA methyltransferase, TrmH family, group 3 n=2
           Tax=Flexibacteraceae RepID=D2QM84_9SPHI
          Length = 276

 Score =  182 bits (464), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 50/161 (31%), Positives = 84/161 (52%), Gaps = 5/161 (3%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAAG 66
           I ++  R +    + ++++    N  AI RTA+  G+  +     G+          ++G
Sbjct: 109 IADVFERGEVPFFLLLDRITDVRNFGAIARTAECTGIQCIVIPGRGAAAINSDAMKTSSG 168

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFRE--IDYTRPTCILMGQEKTG 124
           + + + V     + + V +L+  G+ ++A     +A D  E   D T P  I+MG E+ G
Sbjct: 169 ALNHISVCREPDLTETVKYLQESGITVVACT-EKSARDLYERTTDLTGPMAIIMGSEEDG 227

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           I+ E L + D  + IP++G V SLNVSVA+ +ILYEA RQR
Sbjct: 228 ISPELLRMVDTHVKIPLLGAVGSLNVSVATGVILYEAVRQR 268


>UniRef50_Q2RFM6 RNA methyltransferase TrmH, group 3 n=2 Tax=Clostridia
           RepID=Q2RFM6_MOOTA
          Length = 246

 Score =  182 bits (463), Expect = 9e-45,   Method: Composition-based stats.
 Identities = 51/171 (29%), Positives = 87/171 (50%), Gaps = 7/171 (4%)

Query: 4   TRYARICEMLAR----RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--M 57
             YA + ++LAR     +P   + +++V  PHN+ AI+R+A+AVG H V           
Sbjct: 75  REYADLEDLLARAGEAGEPPFLIMLDRVEDPHNLGAILRSAEAVGAHGVIIPRRRGVGLT 134

Query: 58  RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
             +A AA G+  +V V     +   +  LKG+G+  +     D   +    D+T P  ++
Sbjct: 135 AAVARAAVGAQEYVPVARVTNLARTLEELKGKGLWAIGAA-GDAGQEAFNADFTVPLVLV 193

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           +G E  G++    +  D  + +PM G + SLNV+ A+ +++YE  RQR  A
Sbjct: 194 LGSEGRGLSPLVRSRCDFTVHLPMRGRINSLNVATAATVLMYEVLRQRGQA 244


>UniRef50_B1GZS4 23S rRNA (Guanosine-2'-O-)-methyltransferase n=1 Tax=uncultured
           Termite group 1 bacterium phylotype Rs-D17
           RepID=B1GZS4_UNCTG
          Length = 255

 Score =  182 bits (463), Expect = 9e-45,   Method: Composition-based stats.
 Identities = 39/163 (23%), Positives = 74/163 (45%), Gaps = 5/163 (3%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR--TMAS 62
           +Y  + +++  +   L + +E +  P N+  IIR+ADA G   V      + +       
Sbjct: 92  KYYAVEDII--KNSGLFILLENIQDPGNLGTIIRSADAFGAKAVFVSKGSADIYSDKTIR 149

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
           A  GS   + +     I + +  +K + + + A  L        +I +   +  ++G E 
Sbjct: 150 ATMGSIFHLPIIDSINIKNTLNLMKNKKISVFAASLKGE-KYLNDIKFPNKSAFVIGNEA 208

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            G+  E    AD  + I M G  +SLN + A+++I+YEA + R
Sbjct: 209 NGLRSETENSADTLVKIYMPGNTESLNAATAASIIMYEAAKNR 251


>UniRef50_C8N9X3 23S rRNA (Guanosine-2'-O-)-methyltransferase RlmB n=1
           Tax=Cardiobacterium hominis ATCC 15826
           RepID=C8N9X3_9GAMM
          Length = 243

 Score =  182 bits (462), Expect = 9e-45,   Method: Composition-based stats.
 Identities = 43/160 (26%), Positives = 74/160 (46%), Gaps = 3/160 (1%)

Query: 11  EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG--SRMRTMASAAAGSN 68
           + +A  +  L + ++ +  PHN+ A +R+A A GVH V             +   A G+ 
Sbjct: 85  DAIAGVEKPLLLVLDSIQDPHNLGACLRSAAAAGVHAVLIPNSRAADVTPVVEKVACGAT 144

Query: 69  SWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQE 128
             + +     +   V  ++ QG+ ++       A      D T P  +++G E  GI   
Sbjct: 145 EILPLFRVSNLRREVERMQRQGIWVVGGA-GGAAQSLYATDLTVPLAVIVGNEGEGIRHG 203

Query: 129 ALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
                D  + IPM   ++SLNVSVA  ++L+EA+RQR  +
Sbjct: 204 LREQCDFLVQIPMAEGMESLNVSVACGVMLFEARRQRLFS 243


>UniRef50_B4WGA5 RNA methyltransferase, TrmH family, group 3, putative n=1
           Tax=Synechococcus sp. PCC 7335 RepID=B4WGA5_9SYNE
          Length = 365

 Score =  181 bits (461), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 45/160 (28%), Positives = 79/160 (49%), Gaps = 7/160 (4%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAA 64
           + +   + +  + V  + +  PHN+ AIIR+A+A+G   +  V P  R      T+A  +
Sbjct: 180 VQQAKNKARRPVIVAADGITDPHNLGAIIRSAEAIGAQGI--VIPQRRAVGVTSTVAKVS 237

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTG 124
           AG+   + +     +G A+ +LK     I     ++ A      D++ P  +++G E +G
Sbjct: 238 AGALENIPIARVINLGRALEYLKSNSFWIYGLT-AEAAQSIHTTDFSAPVVLVVGAEGSG 296

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           ++     L DQ + I + G   SLN SVA+ + LYE  RQ
Sbjct: 297 LSLSVQNLCDQLVSIELSGKTPSLNASVATGMALYEIYRQ 336


>UniRef50_C4G1K9 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
           49176 RepID=C4G1K9_ABIDE
          Length = 279

 Score =  181 bits (461), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 44/143 (30%), Positives = 73/143 (51%), Gaps = 3/143 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTHRT 78
            + +E    P N+  I+RTA+A GV  V        +    +  +  GS   +       
Sbjct: 138 LLVLEDTADPGNLGTIMRTAEAAGVTGVIMGKGTVDIFNPKVVRSTMGSIFRLPFTYVED 197

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           + + +  LK  G+   ATHL      +++I Y+  + I++G E  G++ E   LAD  ++
Sbjct: 198 LKETIKELKKSGISFYATHLKGE-KSYKDIKYSGRSAIIVGNEARGLSDEVADLADTYVL 256

Query: 139 IPMIGMVQSLNVSVASALILYEA 161
           IPM G V+SLN +VA+AL++YE 
Sbjct: 257 IPMQGKVESLNAAVAAALMMYEV 279


>UniRef50_Q2S2J6 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Rhodothermaceae
           RepID=Q2S2J6_SALRD
          Length = 253

 Score =  181 bits (460), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 47/176 (26%), Positives = 80/176 (45%), Gaps = 16/176 (9%)

Query: 3   PTRYARICEMLARRQP---------DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP 53
           P RY  +  ML+   P          + + +++V  P N  A++R+A A G   V    P
Sbjct: 80  PIRYREVDAMLSDIAPTWDAVQTAQPMLLVVDRVTDPRNFGAMLRSAVAAGTDGVIV--P 137

Query: 54  GSRMRTMA----SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREID 109
              M  +      A+AG+   + +     +   +  LK +G  +     +       + D
Sbjct: 138 TREMAPLNAAAIKASAGTAPRIPIARTDDLPRVLTQLKERGYFVYGAEGTAE-TPLWDAD 196

Query: 110 YTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           + RP  +++G E  G+  E     D+ + IPM G  +SLNVSVA+ L+++EA R R
Sbjct: 197 WDRPVAVVLGSEGQGLAPEVAEACDELLSIPMRGPAESLNVSVATGLLVFEAARSR 252


>UniRef50_B1AIB3 RNA methyltransferase, TrmH family, group 3 n=15 Tax=Ureaplasma
           RepID=B1AIB3_UREP2
          Length = 239

 Score =  181 bits (460), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 43/161 (26%), Positives = 80/161 (49%), Gaps = 3/161 (1%)

Query: 4   TRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG--SRMRTMA 61
           T      +++  ++  L + ++++  P N  AIIRTA+  GV  +        S    + 
Sbjct: 75  TSLESFLKLIKDKKNALVLILDEIEDPRNFGAIIRTANGFGVDAIIYKKHHQASINDLVI 134

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
             + G+ +++ +     + + + +L+ +G  + AT L   +  + ++DY   T  ++G E
Sbjct: 135 KTSMGAINYIYMIEVNNLSNTIKNLQDEGFWVYATSLL-KSQPYEKVDYANKTVFIVGNE 193

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
             G++   L  ADQ I I M G VQSLNV VA+ +IL   +
Sbjct: 194 NKGVSPLILKNADQSIRIDMFGDVQSLNVGVATGIILAHYR 234


>UniRef50_C2D9C1 Possible tRNA/rRNA methyltransferase n=1 Tax=Atopobium vaginae DSM
           15829 RepID=C2D9C1_9ACTN
          Length = 372

 Score =  181 bits (460), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 38/157 (24%), Positives = 68/157 (43%), Gaps = 3/157 (1%)

Query: 14  ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAGSNSWV 71
           A +Q  L V ++ V    N  AI+R+A+ VG   V           +     +AG+   +
Sbjct: 216 AHKQASLVVLLDHVVDEGNFGAIVRSAEVVGASCVIIANARCASVGVGAYKTSAGAVLHM 275

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            +     +  A+  LK  G  ++            +  +T   C++MG E+ GI+     
Sbjct: 276 PIVQVVNLARAIDELKEHGFWVIGASEHAQQT-VWDAPFTGKVCLIMGSEENGISSLVQK 334

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
             D    +P  G ++SLNV+ A+ ++ YE  RQ + +
Sbjct: 335 KCDFICKLPQRGRIESLNVAQAATVMCYEWMRQNKLS 371


>UniRef50_B3ETE6 Putative uncharacterized protein n=1 Tax=Candidatus Amoebophilus
           asiaticus 5a2 RepID=B3ETE6_AMOA5
          Length = 246

 Score =  181 bits (459), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 52/173 (30%), Positives = 87/173 (50%), Gaps = 7/173 (4%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++P     +  ++     + +  L + ++ V    N+ AI+RTA  VG H +     GS 
Sbjct: 74  LSPVPLVTLSHIVQDTYEKGELPLIIILDGVTDVGNLGAIVRTAVCVGAHALVLPKQGSA 133

Query: 57  M--RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
                    +AG+ + + +     +  ++ +L+  G+Q++A H         ++  T PT
Sbjct: 134 SLGSGAMKTSAGALAHLPICREANLQASINYLQNSGLQVIACH-EKTQTSIYQVKLTVPT 192

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
            IL+G E  GI  + L   D    IPM+G + SLNVSVA+A+ILYE+ RQR N
Sbjct: 193 AILLGSEDKGIQPQLLNKVDVQASIPMVGPISSLNVSVAAAIILYESFRQRNN 245


>UniRef50_A4J4Z3 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Desulfotomaculum
           reducens MI-1 RepID=A4J4Z3_DESRM
          Length = 267

 Score =  181 bits (459), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 46/161 (28%), Positives = 76/161 (47%), Gaps = 3/161 (1%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAG 66
           + +++   Q  L V ++ V  P N+  IIR+ADA G   V  +     +       A  G
Sbjct: 106 LEDIIRPDQKPLVVIVDGVQDPGNLGTIIRSADAAGASGVILLKGTVDIYNPKTLRATMG 165

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           S   + V     + +A+ +L   G+ +L    +   +   + +   P  I++  E  G  
Sbjct: 166 SLFHLPVIQVSDVNEALEYLASIGVTLLVGEPAGG-IPVFKANLQTPVGIIVANEGAGPR 224

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           +E      Q I IPM G  +SLNV++A+++ILYEA RQR  
Sbjct: 225 EEIFRYNHQKITIPMPGCAESLNVAIATSIILYEAIRQRHK 265


>UniRef50_C4Z380 RNA methyltransferase, TrmH family n=1 Tax=Eubacterium eligens ATCC
           27750 RepID=C4Z380_EUBE2
          Length = 279

 Score =  181 bits (459), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 50/163 (30%), Positives = 75/163 (46%), Gaps = 5/163 (3%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--S 62
           + + I +ML      L + +E +  P N+  I+R  +  GV  V        +       
Sbjct: 118 KDSSISDMLT--DNPLLILVENLQDPGNLGTILRMGEGAGVTGVIMSSNTVDIYNPKTIR 175

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
           +  GS   V     +   DAV+  K  G+++ A HL        E DY   T  L+G E 
Sbjct: 176 STMGSIFRVPFVYVQDFSDAVSQCKNAGIKVYAAHLDGKNTYLGE-DYREGTAFLIGNEG 234

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            G+T++    AD  I IPM G V+SLN ++A  ++ YEA RQR
Sbjct: 235 NGLTEDITKQADTLIRIPMQGEVESLNAAIACTILTYEAVRQR 277


>UniRef50_B5YF75 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Dictyoglomus
           RepID=B5YF75_DICT6
          Length = 241

 Score =  181 bits (459), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 47/165 (28%), Positives = 83/165 (50%), Gaps = 10/165 (6%)

Query: 3   PTR-YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA 61
           P R +  I + L  +   + V ++ +  PHN+ AI RT++  G   +  V P +R   + 
Sbjct: 77  PYREWEDIEKTLNNK--SVIVVLDHIQDPHNLGAIARTSEFAGASAI--VIPKARSAGVT 132

Query: 62  ----SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
                A+AG+ S++ V     I + +  LK +G  I+   L    + + +++Y  P  ++
Sbjct: 133 SASFKASAGALSYIPVVRVSNIANFLRELKKKGWFIVGADLDTENL-YNQVNYRFPLALV 191

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
           +G E  G+ +      D  + IP  G V+SLNVSVA  +ILY+ +
Sbjct: 192 VGSEDEGLHRIVKESCDLLVKIPSYGKVESLNVSVALGIILYKIR 236


>UniRef50_B1I0T3 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Clostridia
           RepID=B1I0T3_DESAP
          Length = 251

 Score =  180 bits (458), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 56/173 (32%), Positives = 87/173 (50%), Gaps = 8/173 (4%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           ++   +A + E+L    P L V +  +  P N+ AI+RTA+A GV    AV P  R   +
Sbjct: 81  VSVKDFATVEELLGTENP-LIVVLNAIQDPRNLGAILRTAEAAGVDG--AVVPSRRAAPL 137

Query: 61  A----SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
                  AAG+  ++ V     I   +   K +G+ ++     D  V + + D   P  +
Sbjct: 138 TPAAAKTAAGAVEYLPVARVTNIALTLREFKQKGLWVVGADP-DGPVSYWDADLGGPLAL 196

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
           ++G E  G+ +   A  D  + IPM G V SLN SVA+AL++YEA RQR+  G
Sbjct: 197 VIGGEAGGLGRAVRAECDSLVRIPMSGRVGSLNASVAAALLIYEAVRQRRAGG 249


>UniRef50_A8ZSH6 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Desulfococcus
           oleovorans Hxd3 RepID=A8ZSH6_DESOH
          Length = 256

 Score =  180 bits (458), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 48/171 (28%), Positives = 73/171 (42%), Gaps = 3/171 (1%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--S 62
             A +   +        +  + +  PHN+ A+ RTA   GVH +      +   T A   
Sbjct: 87  PLADLLAAVPSTDTPFILVADGLTDPHNLGALARTALCAGVHGLIIPKDNAASPTPAAVK 146

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
           A+AG+  ++ V     I   +  LK  G+ I             + D T P  +++G E 
Sbjct: 147 ASAGALEFLPVARETNIARVLDALKDAGLWIAGLD-GRGEQTIYDSDLTGPLALVVGDEG 205

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLR 173
            GI +      D  + IP   MV SLN SVA A+ +YEA RQR+   +  R
Sbjct: 206 RGIRRLVGQKCDFILSIPQTDMVHSLNASVAGAVAMYEAFRQRRAKAVIGR 256


>UniRef50_C1ZH70 rRNA methylase, putative, group 3 n=1 Tax=Planctomyces limnophilus
           DSM 3776 RepID=C1ZH70_PLALI
          Length = 271

 Score =  180 bits (457), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 47/166 (28%), Positives = 80/166 (48%), Gaps = 3/166 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG--SRMR 58
           M    YA    +   + P L V ++ +    N+ AIIR A+A+G   +     G      
Sbjct: 103 MPEFPYADFEGLFQAQLPALLVILDGIQDSFNLGAIIRCAEALGAGGIVLPEKGQSGVNS 162

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
             A ++AG+ +++ +     +  A+  LK +GM+ILA     +      +    P C+++
Sbjct: 163 QAARSSAGAVNFLPIYRVPALDRAIDQLKSRGMKILAAT-EKSEQSLWNVVIPAPLCLII 221

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           G E  G++   L+  D  + IPM G   SLN +VA+ ++L E QRQ
Sbjct: 222 GNEGKGVSSALLSACDIQVRIPMAGQTSSLNAAVAAGILLAEIQRQ 267


>UniRef50_C4ZGM4 RNA methyltransferase, TrmH family, group 3 n=8 Tax=Clostridiales
           RepID=C4ZGM4_EUBR3
          Length = 263

 Score =  180 bits (457), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 43/164 (26%), Positives = 77/164 (46%), Gaps = 4/164 (2%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA--A 65
            I E+    + +L + +E +  P N+  ++RT +  GV  +        +    +     
Sbjct: 101 EIDELFKGDKTEL-LVLESIQDPGNLGTMVRTGEGAGVSGIIMNRTTVDIFNPKTVRSTM 159

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           GS   V       + + + + K +G+ + A HL      +   DYT     ++G E  G+
Sbjct: 160 GSLYRVPFYITDDLPETIEYAKSKGVSLYAAHLKGK-CSYDRPDYTGACGFMIGNEGNGL 218

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
           + E   +AD  I IPM G V+SLN ++++ L++YE  RQR+  G
Sbjct: 219 SDEIADMADTYIRIPMEGAVESLNAAISATLLMYECNRQRRLLG 262


>UniRef50_Q11YB9 tRNA/rRNA methyltransferase, TrmH family n=24 Tax=Bacteroidetes
           RepID=Q11YB9_CYTH3
          Length = 268

 Score =  179 bits (456), Expect = 5e-44,   Method: Composition-based stats.
 Identities = 51/171 (29%), Positives = 85/171 (49%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARICEM----LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++   +A +  +        +  L V +++V    N  A+ R+A+ +GV  +     G+ 
Sbjct: 93  LSAINFASLDNIVSACFESGKNPLLVMLDRVTDVRNFGAVARSAECLGVDAMIVPSRGAA 152

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
                    +AG+   + V     + D V +LK  G++I+A      +++  + D T P 
Sbjct: 153 QLNSDAVKTSAGALYHIPVCRVDHLIDTVKYLKQCGLRIIACS-EKASINVYDEDLTDPC 211

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            ILMG E+ GI+ + L  AD  + IPM G + SLNVSVA+ +IL E  RQR
Sbjct: 212 VILMGSEEDGISMDLLRYADAHVTIPMSGHINSLNVSVATGMILSEVTRQR 262


>UniRef50_B1GYT1 23S rRNA methyltransferase n=1 Tax=uncultured Termite group 1
           bacterium phylotype Rs-D17 RepID=B1GYT1_UNCTG
          Length = 251

 Score =  179 bits (455), Expect = 6e-44,   Method: Composition-based stats.
 Identities = 44/171 (25%), Positives = 77/171 (45%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARICEMLARRQP---DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW--PGS 55
           ++P +Y  + +++ R +     L V ++ +  PHN+ AIIR   A G   V         
Sbjct: 81  VSPVQYTELSDLIERSKKSLKPLLVILDGLEDPHNLGAIIRNCVAFGADGVIIPKWRAAG 140

Query: 56  RMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T++ ++AG+   + +        A+  LK     I+            +ID   P  
Sbjct: 141 VNETVSKSSAGAVEHISISRVENTNQAIGLLKENSFWIVGAENGGRI--LEKIDLPFPLA 198

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           +++G E  G+       +D  I IP   ++ SLN S ASA+ILYE  ++R+
Sbjct: 199 VIIGSEGFGLHSLTKKNSDFLISIPQENIISSLNASCASAVILYEIAKKRK 249


>UniRef50_D1R5P1 Putative uncharacterized protein n=1 Tax=Parachlamydia
           acanthamoebae str. Hall's coccus RepID=D1R5P1_9CHLA
          Length = 277

 Score =  179 bits (455), Expect = 7e-44,   Method: Composition-based stats.
 Identities = 47/163 (28%), Positives = 83/163 (50%), Gaps = 4/163 (2%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASA 63
              + + L  +     +  E + KP N+  I+R +DAVG+  +      + +    +  A
Sbjct: 114 LEDLGKQLKNQNNPFLIVAEAIEKPGNLGTILRCSDAVGLDALIVCDACTDIHNPNVVRA 173

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           + G+   V V   +   + +  LK +G+ ILA        +  +ID T P  I +G E+ 
Sbjct: 174 SVGTLFTVPVIESQG-AETLQWLKQKGISILAATPHAK-QELADIDLTGPLAIAVGTEQL 231

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           G++ + +  AD  + IPM G+  SLNV++A+ ++LYEA RQR+
Sbjct: 232 GLSPQWMEQADIQVRIPMYGIADSLNVAMATTILLYEALRQRK 274


>UniRef50_Q112U6 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Oscillatoriales
           RepID=Q112U6_TRIEI
          Length = 234

 Score =  179 bits (454), Expect = 8e-44,   Method: Composition-based stats.
 Identities = 55/201 (27%), Positives = 94/201 (46%), Gaps = 9/201 (4%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           + P R  +I  +L +R  D+TV +E +++PHN SA++R+ D+ GV +VH V   +     
Sbjct: 17  ITPARREKILSVLQQRTRDITVILEDIYQPHNASAVLRSCDSFGVQDVHIVENKNIFTIT 76

Query: 61  ASAAAGSNSWVQVKTHR-----TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
            S   GS+ W+ +  +         + +  LK +G  I AT      +   E+       
Sbjct: 77  QSVTIGSDRWLTLYRYNEQSINNTEECLKRLKNEGYVIAATTPYKEHITIEELSVNTKVA 136

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLREN 175
           ++ G E  G+++ A   AD  + IPM+G  +S N+SV++AL LY    + +        N
Sbjct: 137 LMFGSEINGLSEYAKNNADVSVKIPMVGFSESFNISVSAALCLYNLMSRLKKEH----NN 192

Query: 176 SMLPEAEQQRLLFEGGYPVLA 196
             L E E+  L        + 
Sbjct: 193 WKLTETEKLDLELNWLQKSIK 213


>UniRef50_Q7VQP0 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=2
           Tax=Candidatus Blochmannia RepID=RLMB_BLOFL
          Length = 254

 Score =  179 bits (454), Expect = 9e-44,   Method: Composition-based stats.
 Identities = 46/168 (27%), Positives = 77/168 (45%), Gaps = 5/168 (2%)

Query: 9   ICEMLARRQP--DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS--RMRTMASAA 64
           +   L  +     L + ++ +  PHN+ A IR+ADA GVH +      S     T+   A
Sbjct: 85  LLHFLKTKNNIIPLLLVLDGITDPHNLGACIRSADAAGVHMIIVPRDRSANVNATVRKVA 144

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTG 124
           +GS+  V       +   +  LK   + I+ + L  N +         P  ++MG E +G
Sbjct: 145 SGSSDRVPFVRVTNLSRTLKLLKKYNIYIVGSVLRSNQI-LFNTRLIDPIALVMGSESSG 203

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYL 172
           I +      D+ + IP +    SLNVSVA+ + L+E  RQR+    ++
Sbjct: 204 IRRLTRENCDKLVHIPTLQSTVSLNVSVATGIFLFETVRQRKYQNGFI 251


>UniRef50_Q6AJ92 Related to tRNA/rRNA methyltransferase n=1 Tax=Desulfotalea
           psychrophila RepID=Q6AJ92_DESPS
          Length = 295

 Score =  178 bits (453), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 50/161 (31%), Positives = 79/161 (49%), Gaps = 2/161 (1%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASA 63
             +  + + R +    +  + +  PHN+ AI+R+A A G   V      S     T A +
Sbjct: 131 LQKFKDAVDRGEKPRIIVCDSLQDPHNLGAIVRSALASGAIGVLLTRERSAPLGGTAAKS 190

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           +AG+ S + +     +  ++A LK  G  +       +AV   + D   P CI++G E T
Sbjct: 191 SAGAISHMDICQVTNLVKSLAELKKVGAWVFGAIKDADAVSLFDADLNVPACIVVGSEGT 250

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           GI        D  + IPM+G + SLN SVA+A+IL+EA RQ
Sbjct: 251 GIRPLVRRECDIQLSIPMVGELDSLNSSVAAAVILFEAMRQ 291


>UniRef50_C1TM87 rRNA methylase, putative, group 3 n=1 Tax=Dethiosulfovibrio
           peptidovorans DSM 11002 RepID=C1TM87_9BACT
          Length = 269

 Score =  178 bits (453), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 44/160 (27%), Positives = 77/160 (48%), Gaps = 7/160 (4%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASA 63
            + +   ++ P L + M+ V  PHN  A+IRTA+AVG   V  ++P  R      T+   
Sbjct: 107 DLSQFSPKKGPSLLLAMDHVKDPHNFGAMIRTAEAVGALGV--IYPSRRSVGVTGTVIKT 164

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           +AG+   V +     +  ++  LK +G  ++     +   D           +++G E  
Sbjct: 165 SAGAAFRVPLYEVTNLVRSMEILKKEGYWVVGLD-HEEPRDIWSSPLPDKLVLMVGSEGE 223

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           G+++ +    D    IPM+G   SLN SVA+AL ++E +R
Sbjct: 224 GLSRLSSERCDDLRRIPMVGKTGSLNASVAAALGMFEWRR 263


>UniRef50_A5F9W1 tRNA/rRNA methyltransferase (SpoU) n=16 Tax=Bacteroidetes
           RepID=A5F9W1_FLAJ1
          Length = 220

 Score =  178 bits (453), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 51/206 (24%), Positives = 103/206 (50%), Gaps = 4/206 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           +   R  +  ++L  R    T+ +E V++ HN SA++R+ +  G+ E++ +      R  
Sbjct: 14  LTDNRKEKFLKVLENRTKHFTIAVEDVYQMHNTSAVMRSCEVFGIQELNIIEQRFGKRID 73

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A G+  WV +    T+   ++ L+ +G QI+AT   +N    ++ D ++P+ +  G 
Sbjct: 74  KEIALGAQKWVDINRFDTVDGCISSLRDKGYQIIATTPHENDCLIQDFDISKPSALFFGT 133

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G++ E L  AD  + IPM+G  +SLN+SV++A+I+     + +N+ +       L +
Sbjct: 134 EKDGLSPEILEKADGFLKIPMVGFTESLNISVSAAIIIQNLTNRLRNSDI----KWKLSD 189

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPY 206
            E  +   +     +  + + +   Y
Sbjct: 190 EEILQKRLDWAKNSIRDIKRIEARYY 215


>UniRef50_C4L451 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Exiguobacterium sp. AT1b
           RepID=C4L451_EXISA
          Length = 248

 Score =  178 bits (453), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 4/152 (2%)

Query: 15  RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQ 72
            R+    + +++V  P N+  +IRTADA G   V             +  A  GS   V 
Sbjct: 99  ERKMKKVLVLDRVQDPGNLGTMIRTADAAGFDTVLLGKGTVDPFNAKVVRATQGSLFHVN 158

Query: 73  VKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALAL 132
           V +   + + +  LK  G  +  T LS  A  + ++ +     +++G E  G+  + LAL
Sbjct: 159 VTSV-DLLEKLPELKEDGFHVYGTALS-KATSYEQVAFEEKVALVIGNEAQGVHADVLAL 216

Query: 133 ADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            D  + IP++G V+SLN +VA+ +++Y    Q
Sbjct: 217 CDTRVHIPVLGDVESLNAAVAAGILMYRIALQ 248


>UniRef50_B5JMU7 RNA methyltransferase, TrmH family n=1 Tax=Verrucomicrobiae
           bacterium DG1235 RepID=B5JMU7_9BACT
          Length = 273

 Score =  178 bits (452), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 42/157 (26%), Positives = 82/157 (52%), Gaps = 2/157 (1%)

Query: 10  CEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNS 69
            + L    P   + +E + KP N+  I+R+ADA GV  V      + +    +  + +  
Sbjct: 111 LDDLQLSDPPFLLIVEAIEKPGNLGTILRSADAAGVDAVICCDSVTDLFNPNAVRSSTGV 170

Query: 70  WVQVKTHR-TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQE 128
              + T   +  + +  ++ +G++ +AT    + + + + D   P  I+MG E+ G++++
Sbjct: 171 LFSMPTVTASSDEVIKWIRQKGIRTIATTPHTD-ILYTDTDLRGPLAIVMGSEQFGLSEK 229

Query: 129 ALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            L+  D  ++IPM G   SLNV++A+ + L+EA RQR
Sbjct: 230 WLSACDTKVLIPMAGQADSLNVAMATLITLFEAVRQR 266


>UniRef50_B3PM16 SpoU class tRNA/rRNA methyltransferase n=1 Tax=Mycoplasma
           arthritidis 158L3-1 RepID=B3PM16_MYCA5
          Length = 229

 Score =  177 bits (451), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 44/155 (28%), Positives = 87/155 (56%), Gaps = 6/155 (3%)

Query: 13  LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR----MRTMASAAAGSN 68
           + + +P+L + ++ +  PHN  AIIR A+  G+   H + P +R      T+   ++G+ 
Sbjct: 75  IFKDKPNLVLMLDHIQDPHNFGAIIRNANGFGIK--HIIIPKNRACEVTPTVLKISSGAF 132

Query: 69  SWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQE 128
           + +++    ++ D +  L+  G  I ++ L D A    +  +  PTC+++G E++G++  
Sbjct: 133 TEIKIIRVGSLFDTLKELQKNGFWIYSSTLDDKATKLHKTKFATPTCLIVGNEESGVSHT 192

Query: 129 ALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
            +  +D  + I   G VQSLNV+ A+A++LYEA +
Sbjct: 193 LIKHSDALVYIEQKGTVQSLNVASATAVLLYEATK 227


>UniRef50_B6IRN7 RNA methyltransferase, TrmH family, group 3 n=4 Tax=Proteobacteria
           RepID=B6IRN7_RHOCS
          Length = 251

 Score =  177 bits (451), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 48/162 (29%), Positives = 73/162 (45%), Gaps = 3/162 (1%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASA 63
              +C         L + ++QV  PHNV AI+R+A A G   V      +   T  +A  
Sbjct: 91  VEDVCIAAESEPQALVIVLDQVTDPHNVGAIMRSAAAFGARAVIVQDRHAPPVTGVLAKT 150

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           A+G+   V +     +  A+  LK  G   +       A    E+D T  T +++G E  
Sbjct: 151 ASGAVDAVPLVRVTNLARALDTLKQAGFWTVGLD-ESGARPLHEVDLTGRTALVLGSEGE 209

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           G+ +      D+   +P  G V SLNVS A+A+ LYE  R+R
Sbjct: 210 GLRRLTGERCDEIARLPTGGPVGSLNVSNAAAVALYEVARRR 251


>UniRef50_B1I4I6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Candidatus Desulforudis
           audaxviator MP104C RepID=B1I4I6_DESAP
          Length = 272

 Score =  177 bits (450), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 50/167 (29%), Positives = 78/167 (46%), Gaps = 3/167 (1%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAA 65
            +  +L  R   L V ++ +  P N+  IIRTADA  +  V  +     +    +  A+A
Sbjct: 106 SLDVLLQGRGTPLVVVLDGLQDPGNLGTIIRTADACELQGVITLEGTVDLFHPKVVRASA 165

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G+   +           +    G G+Q        +     E D++RPT + MG E  G 
Sbjct: 166 GALFHLPAFGDLPAPAVLEFFTGAGVQKFVADPRGD-YSLYECDFSRPTALFMGNEARGC 224

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYL 172
            +   A AD+ + IPM G  +SLNV VA++L +YEA RQR  + + L
Sbjct: 225 GEMLHAAADRVVAIPMPGQAESLNVGVAASLFIYEAVRQRLKSSLSL 271


>UniRef50_D1VT15 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Peptoniphilus
           lacrimalis 315-B RepID=D1VT15_9FIRM
          Length = 234

 Score =  177 bits (450), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 35/161 (21%), Positives = 72/161 (44%), Gaps = 4/161 (2%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMAS 62
            +  + +    ++    + ++++  PHN+ AI R+A       +        +   T+  
Sbjct: 76  DFQELLDENKDKKEFRLLILDKMEDPHNLGAIARSALFFNFDGIIIPKHREALVNDTVYK 135

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
            + G+   V +     +   +  LK  G  I A  L  +  + +++D++    I++G E 
Sbjct: 136 TSQGAVDNVNICQVTNLSQTIEKLKKAGFWIYAALLEGD--NIKDVDFSGKVAIIIGNEG 193

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
            GI+   +  +D  + IP +    SLN SVA+ +I+YE  R
Sbjct: 194 KGISDNLIKASDFKVKIPNLSEFDSLNASVAAGIIMYEVIR 234


>UniRef50_Q84X80 CR004 protein n=1 Tax=Chlamydomonas reinhardtii RepID=Q84X80_CHLRE
          Length = 316

 Score =  177 bits (449), Expect = 4e-43,   Method: Composition-based stats.
 Identities = 76/184 (41%), Positives = 116/184 (63%), Gaps = 4/184 (2%)

Query: 4   TRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA-S 62
            R  RI E++A+R   +   +E ++   N++A+ RTADA+G   VHAV        M+  
Sbjct: 76  ERVKRIEEVVAKRTFTVLPIVEGLYDMGNLAAVCRTADALGYGAVHAVNKADGKFKMSQR 135

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
            AAG++ W+ VK   + G+ +A +K  G QI+ THL+ +++  +E+D+TRPT +++G EK
Sbjct: 136 TAAGADKWLDVKAWDSTGECLAAMKAAGYQIVTTHLTQSSITIQEVDWTRPTAVVLGNEK 195

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAE 182
            G++ EA+A AD   IIPM GMV+S N+SVA+ALILYEAQ+QR      L  ++ L   +
Sbjct: 196 FGVSAEAVAAADACAIIPMTGMVESFNISVANALILYEAQQQRIR---RLGSHADLSPDQ 252

Query: 183 QQRL 186
           Q  L
Sbjct: 253 QMAL 256


>UniRef50_Q6MNP1 Putative RNA methylase n=1 Tax=Bdellovibrio bacteriovorus
           RepID=Q6MNP1_BDEBA
          Length = 238

 Score =  176 bits (448), Expect = 4e-43,   Method: Composition-based stats.
 Identities = 67/183 (36%), Positives = 100/183 (54%), Gaps = 3/183 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           +   R  +I +++A R  D  V +E ++   N+SA++R+A+ +G    H +    + +  
Sbjct: 29  LTDERRQKIEKVVALRNFDTAVVLEGIYDRGNISAVMRSAEGLGFGNFHVIETQEKFKEA 88

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
                G++ WV+VK  +   D V  LK QG +I  THL  NA    EID++  T +++G 
Sbjct: 89  NRVTQGADKWVEVKKWKKTADCVKALKNQGYKIYVTHLDANAKPLHEIDFSGKTALVLGN 148

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E+ G+T E +A ADQ IIIPM G VQS N+SVA AL LY   + R         N+ L E
Sbjct: 149 ERDGVTPEMIAAADQTIIIPMTGFVQSFNISVAGALGLYHISQDRLK---RRGTNASLTE 205

Query: 181 AEQ 183
            EQ
Sbjct: 206 EEQ 208


>UniRef50_C9RBD1 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Ammonifex
           degensii KC4 RepID=C9RBD1_AMMDK
          Length = 254

 Score =  176 bits (448), Expect = 5e-43,   Method: Composition-based stats.
 Identities = 57/179 (31%), Positives = 89/179 (49%), Gaps = 11/179 (6%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           ++P  YA + E+LA   P   + +  +  P N+ AI+RTA AVGV  V  + P  R   +
Sbjct: 79  VSPYNYASLDEILAT-HPSCLLVLAYITDPRNLGAILRTAAAVGVEGV--IIPSRRAAGL 135

Query: 61  A----SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
                 A+AG    V+V     +   + +LK QG  +L    +D  V   E ++  P  +
Sbjct: 136 TAEALKASAGGAEHVKVARVTNLAQTLRYLKEQGFWVLGAE-ADAKVSLWEAEWNEPLVV 194

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR---QNAGMYL 172
           ++G E TG+ +      D  + IP    +  LN SVA+A+ILYE  R++   +NAG  L
Sbjct: 195 VIGGEDTGLGKVVRRECDVLVRIPTTAKMPCLNASVAAAVILYEVLRRQMKGKNAGDNL 253


>UniRef50_A2U3D3 SpoU rRNA methylase n=2 Tax=Flavobacteriaceae RepID=A2U3D3_9FLAO
          Length = 248

 Score =  176 bits (448), Expect = 5e-43,   Method: Composition-based stats.
 Identities = 44/171 (25%), Positives = 81/171 (47%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARI----CEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++P  +  +     + L   +    + ++Q+    N  AIIRTA+  GV+ +     GS 
Sbjct: 75  ISPIDFYDLETLLDDTLEAEKVPFFLILDQLSDVRNFGAIIRTAECTGVNGIIIQKNGSA 134

Query: 57  MRT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
                    +AG+   + +     I DA+  L+   ++ +A     ++    ++++ +P 
Sbjct: 135 PVNAETIKTSAGAAFKMPICKVDHIKDALFILQASNIKTVAATEKTDS-SIYDVNFNQPI 193

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            I+MG E  G+    L + D    +P+ G ++SLNVSVA  + LYE  RQR
Sbjct: 194 AIIMGSEHRGVNPSVLKMVDYKAKLPLSGNIESLNVSVACGVFLYETVRQR 244


>UniRef50_B3RWG3 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
           RepID=B3RWG3_TRIAD
          Length = 246

 Score =  176 bits (448), Expect = 5e-43,   Method: Composition-based stats.
 Identities = 59/191 (30%), Positives = 97/191 (50%), Gaps = 4/191 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAV-WPGSRMRT 59
               R  ++   +  R   + V +E +    N  AI RT DA+G    H +  P  R++T
Sbjct: 50  FTKERLDKMTNAVKNRTRSIAVVLEGITNEGNEQAIYRTMDALGFQTAHRIPSPLYRLKT 109

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
                AG+  W+ +++ ++  + ++ LK  G +ILAT   +        D++  T +++G
Sbjct: 110 CGRTDAGAMKWIDIESWKSTEECISQLKSCGYKILATSSENKTKTLDSFDFSNKTAVVLG 169

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E+ GI++EA+ L D    I M+G V+S NVSVA+A+ILY   + R     Y   +  L 
Sbjct: 170 SEQEGISKEAMNLVDNVFRISMVGFVESYNVSVAAAIILYHIYQDRIRKLGY---HGDLT 226

Query: 180 EAEQQRLLFEG 190
           EAEQ  LL + 
Sbjct: 227 EAEQDDLLLQY 237


>UniRef50_C7MMG3 rRNA methylase, putative, group 3 n=1 Tax=Cryptobacterium curtum
           DSM 15641 RepID=C7MMG3_CRYCD
          Length = 300

 Score =  176 bits (447), Expect = 6e-43,   Method: Composition-based stats.
 Identities = 42/184 (22%), Positives = 80/184 (43%), Gaps = 19/184 (10%)

Query: 3   PTRYARICEMLARRQP----------------DLTVCMEQVHKPHNVSAIIRTADAVGVH 46
           P  YA + +++AR                    L + ++ +    N+ AI R+A++VG  
Sbjct: 76  PFAYASLDDIIARGNDQAVSLAVSHSSSAAPCALIIVLDHITDAGNLGAIARSAESVGAA 135

Query: 47  EVHAVWPGS--RMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVD 104
            +      S     +   ++AG+ S + V     +  A+A LK +G  +           
Sbjct: 136 GIIIPNKRSAYVTASTYKSSAGAISHIPVAQVANLQQALARLKNEGYWVAGASEKAEGG- 194

Query: 105 FREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
             + + T   C++MG E TG+ +      D  + +P  G+V SLNV+ ++ + +YE  RQ
Sbjct: 195 IWDANLTGNVCLVMGNENTGLARLTQEACDFFVSLPQRGVVSSLNVAQSATVCMYEWLRQ 254

Query: 165 RQNA 168
            + +
Sbjct: 255 NRLS 258


>UniRef50_Q3A6R3 rRNA methyltranferase n=2 Tax=Desulfuromonadales RepID=Q3A6R3_PELCD
          Length = 246

 Score =  176 bits (447), Expect = 6e-43,   Method: Composition-based stats.
 Identities = 35/149 (23%), Positives = 64/149 (42%), Gaps = 2/149 (1%)

Query: 19  DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW--PGSRMRTMASAAAGSNSWVQVKTH 76
            + + ++ +  PHN+ A+ R+A+AVG   +                A+AG+ +++ V   
Sbjct: 96  GVILVLDGITDPHNLGALARSAEAVGCQGIVLPKDRSCPITAAAEKASAGALAYLPVCRV 155

Query: 77  RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQD 136
             +  ++   K  G  +        +    + D      +++G E  G+        D  
Sbjct: 156 TNVARSLEVFKQAGFWVYGLAGDAGSQSLYDTDLRGNVVLVVGGEGKGLRDNVRKHCDAL 215

Query: 137 IIIPMIGMVQSLNVSVASALILYEAQRQR 165
           + IPM G V SLN SVA  + L+E  RQ+
Sbjct: 216 LAIPMRGQVSSLNASVAGGVALFEVLRQQ 244


>UniRef50_C7H9L6 RNA methyltransferase, TrmH family, group 3 n=3 Tax=Ruminococcaceae
           RepID=C7H9L6_9FIRM
          Length = 267

 Score =  176 bits (447), Expect = 6e-43,   Method: Composition-based stats.
 Identities = 49/173 (28%), Positives = 84/173 (48%), Gaps = 11/173 (6%)

Query: 2   NPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG--S 55
           +   Y  + ++L     + +P   V  + +  PHN+ A++R+A   G H +     G  S
Sbjct: 94  SEIEYVTVEDLLNVAREKGEPPFLVLSDGIEDPHNLGAVMRSALLCGAHGIVIPKRGGAS 153

Query: 56  RMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T+  ++AG+   + V     IG+ +  LK QG+ +    +    V  R+ + T P  
Sbjct: 154 VTPTVIKSSAGAAERLPVARVANIGETIRRLKDQGVFVYCADMDG--VPLRKNNLTGPIA 211

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGM---VQSLNVSVASALILYEAQRQR 165
           +++G E +G++Q    L D  + + M      V S NVSVA+ +ILYE Q QR
Sbjct: 212 LVLGSEGSGVSQLVKKLCDGVVRLDMAAQGTGVDSFNVSVAAGIILYEIQSQR 264


>UniRef50_D1Y8A8 RNA methyltransferase, TrmH family, group 3 (Fragment) n=1
           Tax=Pyramidobacter piscolens W5455 RepID=D1Y8A8_9BACT
          Length = 269

 Score =  175 bits (446), Expect = 7e-43,   Method: Composition-based stats.
 Identities = 43/163 (26%), Positives = 69/163 (42%), Gaps = 3/163 (1%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR--TM 60
           P     + + L  + P L V ++    PHN+ A+IRTA+  G   V      S     T+
Sbjct: 98  PADLDGVVDALDPQAPALIVLLDHCQDPHNLGAVIRTAEVAGAACVVCQNDRSATVNGTV 157

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              +AG+   + V     +G AV  LK +G  ++      +              +++G 
Sbjct: 158 VKTSAGAAFRLPVAQVVNVGRAVERLKRKGFWVVGLDHRTDET-VWSSALPERLALVVGS 216

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           E  GI+       D  +  PM G   +LN SVA+AL ++E  R
Sbjct: 217 EGEGISALTAKKCDMLVKFPMAGRTGNLNASVAAALGMFEWVR 259


>UniRef50_B8DUY4 tRNA/rRNA methyltransferase n=5 Tax=Bifidobacterium
           RepID=B8DUY4_BIFA0
          Length = 331

 Score =  175 bits (446), Expect = 8e-43,   Method: Composition-based stats.
 Identities = 44/175 (25%), Positives = 77/175 (44%), Gaps = 11/175 (6%)

Query: 4   TRYARICEMLARRQP-----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
            R AR  EM   +        L + ++ +  P N+ A+IR+A A GV+ V    P  R  
Sbjct: 155 ERKARAMEMADSKASRLSARPLFIALDGITDPQNLGAVIRSAAAFGVNGVIL--PERRSA 212

Query: 59  TMA----SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
           ++       +AG+ + + +     +  A+  LK +G   +      + +       T P 
Sbjct: 213 SVNAAAWKVSAGAAAHMPIARVVNLTKAIEALKERGYYSIGLDGGGSKLVGETGFETDPL 272

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
            +++G E  G+++      D    IP+   V+SLN SVA+ + LY     R+ AG
Sbjct: 273 VVVLGSEGKGLSRLTREACDAIASIPITSAVESLNASVAAGIALYATVNARRKAG 327


>UniRef50_O51468 Uncharacterized tRNA/rRNA methyltransferase BB_0516 n=21
           Tax=Borrelia RepID=Y516_BORBU
          Length = 228

 Score =  175 bits (445), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 36/162 (22%), Positives = 78/162 (48%), Gaps = 3/162 (1%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAV--WPGSRMRTMAS 62
            +  + E   +++    + ++++  P N  AI+RTA+   +  V            T+  
Sbjct: 64  DFENLLETFKKKENAFILLLDEIEDPQNFGAILRTAEQFSIDLVITTQKRSAKDNSTVLR 123

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
            ++G++ +V+  T   I + +  LK  G  I    +    ++  +I+  +   +++G E 
Sbjct: 124 TSSGASQYVKKMTVTNINNTINLLKNYGFWIYTGDIKGQDINKIKIN-DKKIALILGNEG 182

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            G+ +     +D  I IP  G + SLNVSV++ ++++E +RQ
Sbjct: 183 KGVHKLIKENSDFLIRIPTSGKIDSLNVSVSTGILIFEIKRQ 224


>UniRef50_C9A4E5 RNA methyltransferase n=3 Tax=Enterococcus casseliflavus
           RepID=C9A4E5_ENTCA
          Length = 259

 Score =  175 bits (444), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 45/161 (27%), Positives = 81/161 (50%), Gaps = 9/161 (5%)

Query: 7   ARICEMLARRQPDL------TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR-- 58
             I  ++ +++ DL       + ++ V  P NV  +IRTADA G   V      + +   
Sbjct: 96  QGIFAVVEKQEQDLQTLTGNWLILDNVQDPGNVGTMIRTADAAGFSGVFLGEGTADLYST 155

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
            +  +  GSN  + +     I   +  L+  G+ I  T L+  AV + E+   +    ++
Sbjct: 156 KVLRSMQGSNYHLPIVEGA-IPPFLKQLQAAGVAIYGTELNKEAVPYTELPKGQAAAFIL 214

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILY 159
           G E  G+ QE LAL D+++ IP+ G  +SLNV++A+ +++Y
Sbjct: 215 GNEGQGVNQELLALTDKNLYIPIYGQAESLNVAIAAGILMY 255


>UniRef50_A0M5B1 TrmH family tRNA/rRNA methyltransferase n=16 Tax=Bacteroidetes
           RepID=A0M5B1_GRAFK
          Length = 245

 Score =  175 bits (444), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 53/171 (30%), Positives = 82/171 (47%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++P  +  + +++   Q      L V ++ +    N  AIIRTA+  GV  +     GS 
Sbjct: 75  ISPIGFVSLEKLVEDSQKSSTTPLFVLLDGITDVRNFGAIIRTAECCGVTGIIIQEKGSA 134

Query: 57  M--RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
                    +AG+   + +     I DAV HL+   ++++A     + V   +ID  +P 
Sbjct: 135 PINADTVKTSAGAVFNIPICKVNHIKDAVFHLQTYDIKLIAATEKTDDV-IFDIDLKQPI 193

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            I+MG E  GI+   L   D    +PM+G + SLNVSVA    LYEA RQR
Sbjct: 194 AIIMGDEAKGISNSILKSVDYKAKLPMLGSIASLNVSVACGAFLYEAVRQR 244


>UniRef50_C9M6N6 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Jonquetella
           anthropi E3_33 E1 RepID=C9M6N6_9BACT
          Length = 278

 Score =  174 bits (443), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 44/168 (26%), Positives = 80/168 (47%), Gaps = 5/168 (2%)

Query: 8   RICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASA 63
            + ++L +    P L + +++   PHN+ ++IRTA+A G   V      S     T+  A
Sbjct: 112 SLDDLLDQLAGGPALVILLDRCQDPHNLGSVIRTAEAAGASAVLVPKDRSVRLTGTVVKA 171

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           +AG+     V +   +  A+  LK  G  ++     +++    ++ + + T + +G E T
Sbjct: 172 SAGAALRFPVISVVNVKRALDDLKEAGFWVVGLA-GESSEPLGKLAWDQRTVLAVGAEGT 230

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMY 171
           G+ +      D    IPM G  +SLN  VA+AL  YE  R+   +G +
Sbjct: 231 GLAELTRKSCDFLARIPMSGQAESLNAGVAAALGAYEWARRFHFSGDF 278


>UniRef50_B1ZVF9 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Opitutaceae
           RepID=B1ZVF9_OPITP
          Length = 296

 Score =  174 bits (442), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 45/152 (29%), Positives = 79/152 (51%), Gaps = 4/152 (2%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAAGSNSWVQV 73
           ++    + +E + KP N+  I+R+ADA G   V    P + +    +  A+ G    V +
Sbjct: 145 QRAPFILVVEAIEKPGNLGTILRSADAAGCDAVIVCDPVTDIFNPNVVRASTGVLFSVPL 204

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALA 133
               +    +A L+ QG++ +AT  +   + + + D   P  I+MG E+ G+++  L   
Sbjct: 205 VVAES-APVLAWLRAQGVRTIATTPAAEKL-YTDADLRGPLAIVMGSEQYGLSEFWLKNC 262

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           D  + IPM G   SLNV++A+ + L+EA RQR
Sbjct: 263 DLPVRIPMAGQADSLNVAMATIITLFEAVRQR 294


>UniRef50_C0WU39 RNA methyltransferase n=3 Tax=Lactobacillus RepID=C0WU39_LACBU
          Length = 255

 Score =  174 bits (442), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 36/155 (23%), Positives = 79/155 (50%), Gaps = 3/155 (1%)

Query: 11  EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAA--GSN 68
           E +  +     + ++ +  P N+  ++RTADA G++ V      + +       +  GS 
Sbjct: 102 ESIPEKLGGSWLMLDNIQDPGNIGTMVRTADAAGMNGVIFGKGTADIYNPKVVRSMQGSQ 161

Query: 69  SWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQE 128
             V++ +   +   +A      + +  T L+D A+ + +++ T+   ++MG E  G++ +
Sbjct: 162 FHVRLYSG-DLAVWMAAFNKHNVPVYGTELNDQAISYDDVEPTKQFALVMGNEGNGVSAD 220

Query: 129 ALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
            L   DQ++ IPM G  +SLNV+VA+ ++++   +
Sbjct: 221 LLDKTDQNLYIPMNGEAESLNVAVATGILIFHFVK 255


>UniRef50_Q7TU91 tRNA/rRNA methyltransferase n=3 Tax=Prochlorococcus marinus
           RepID=Q7TU91_PROMP
          Length = 428

 Score =  174 bits (442), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 44/149 (29%), Positives = 67/149 (44%), Gaps = 7/149 (4%)

Query: 14  ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR----TMASAAAGSNS 69
           ++    + V ++ V  PHN  AIIR+A+A     +    P  R      T+A  AAG+  
Sbjct: 277 SKSSNPIIVALDGVTDPHNFGAIIRSAEAFDCKGIIV--PQRRSAGLTGTVAKVAAGALE 334

Query: 70  WVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEA 129
            + V     +  A+  LK +G  I+     D  V   E     P  +++G E  GI+   
Sbjct: 335 HIPVSRVVNLNRAIDELKKKGFIIIGLS-GDGQVPISEFKEKAPVVVIVGAENKGISLLV 393

Query: 130 LALADQDIIIPMIGMVQSLNVSVASALIL 158
               D  + IP+ G   SLN SVA+A+ L
Sbjct: 394 QKKCDYLLKIPLKGKTSSLNASVAAAISL 422


>UniRef50_Q0VMF8 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Alcanivorax
           RepID=Q0VMF8_ALCBS
          Length = 251

 Score =  174 bits (442), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 45/167 (26%), Positives = 78/167 (46%), Gaps = 3/167 (1%)

Query: 2   NPTRYARICEMLARRQ-PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
            P   + + + L  +    L + +E V  PHN+ A +R+ADA GV  V      +   T 
Sbjct: 82  RPLDESALLQWLDGKPAKPLLLVLENVTDPHNLGACLRSADAAGVQAVIVPRRNAAGLTP 141

Query: 61  A--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
                A G+   +       +   +  L+ +G+ ++ T L + +             ++M
Sbjct: 142 VACRTAVGAAESLAYYEIGNLASLLDQLRDRGVWVVGTALEERSESLFTFQAPESLAVVM 201

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           G E +G+ +      DQ + IPM G VQSLNVSVA+ ++L++ + QR
Sbjct: 202 GAEGSGLKRLTRDKCDQLLEIPMAGEVQSLNVSVATGVMLFQVRAQR 248


>UniRef50_D1NAJ1 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Victivallis vadensis
           ATCC BAA-548 RepID=D1NAJ1_9BACT
          Length = 273

 Score =  174 bits (441), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 46/153 (30%), Positives = 81/153 (52%), Gaps = 4/153 (2%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQV 73
           R   L +  E V KP N+ +++R+ADA GV         + +    +  A+ G+   V +
Sbjct: 116 RPNGLYLVAEAVEKPGNLGSMLRSADAAGVDGFIICNKCTDIYNPNVIRASTGALFSVPL 175

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALA 133
                  +A   LK   ++ LA     + + + ++D T+   I++G E+TG+T+  +  +
Sbjct: 176 AEAEN-QEAYDWLKKNNIRTLAATPHTDQI-YTDVDMTQAVAIVVGTEQTGLTELWMEHS 233

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           D  + IPM+G + SLNV+ A+ ++LYEA RQR 
Sbjct: 234 DLPVRIPMLGKIDSLNVATATTILLYEAARQRN 266


>UniRef50_D1PXH3 SpoU rRNA methylase n=1 Tax=Prevotella bergensis DSM 17361
           RepID=D1PXH3_9BACT
          Length = 269

 Score =  174 bits (441), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 53/162 (32%), Positives = 83/162 (51%), Gaps = 4/162 (2%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAA 65
           R    L   +  L V +E V KP N+ A++R+ADA     V    P + +    +  ++ 
Sbjct: 109 RTLADLDLPESPLIVVLESVEKPGNLGAVLRSADASKADAVIVCNPLTDLFNPNLIRSSI 168

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G+   V      +    +  LK + ++IL   L D+A  + + D    T I+MG E TG+
Sbjct: 169 GAIFTVPTVACSS-QACMNFLKERNIKILTAQLQDSA-PYYDSDMRGGTAIVMGTESTGL 226

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           T      AD  I IPM+G + SLNVSV++A++++EA RQR  
Sbjct: 227 TDAWRKAADAHIRIPMLGQLDSLNVSVSAAILMFEAVRQRSF 268


>UniRef50_B8D292 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Halothermothrix orenii H
           168 RepID=B8D292_HALOH
          Length = 270

 Score =  174 bits (441), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 40/155 (25%), Positives = 82/155 (52%), Gaps = 6/155 (3%)

Query: 12  MLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNS 69
           +   R   + + ++++  P N+  IIRTA A G+  +  +     +    +  A+ G+  
Sbjct: 110 LFHNRNRGIILILDRIQDPGNMGTIIRTAVAAGIEGIICLKGSVDIYNLKVIRASMGAIF 169

Query: 70  WVQVKTHRTIGDAVAHLKGQ--GMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQ 127
            + + T  +    +  ++ +    +++ T L+  +  + EIDY  P  +++G E  GI +
Sbjct: 170 SIPILTGVSFKR-LQKIRDEYPDYKLICTDLN-TSKFYHEIDYQEPLMLVIGNEARGIRE 227

Query: 128 EALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
           E L+LAD  I IP++G + SLN +V++A++LY+  
Sbjct: 228 ELLSLADIKIKIPLMGNIDSLNAAVSTAIVLYDIV 262


>UniRef50_Q8DNE3 Possible rRNA/tRNA methylase n=69 Tax=Streptococcaceae
           RepID=Q8DNE3_STRR6
          Length = 252

 Score =  173 bits (440), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 47/167 (28%), Positives = 78/167 (46%), Gaps = 7/167 (4%)

Query: 2   NPTRYARICEMLARRQPDL----TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM 57
            P     + +     Q DL     + +E V  P NV  IIRTADA G   V      + +
Sbjct: 87  TPQGIVAVVQKEEVGQADLSQGKFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADI 146

Query: 58  RTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
            ++    +  GS+  + +    +    +   K   + +LAT LS ++VD+RE+       
Sbjct: 147 YSLKTLRSMQGSHFHLPIYRMTSPA-LLDETKKVAIPVLATTLSKDSVDYRELPSIENFV 205

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
           ++MG E  GI+      ADQ + I M G  +SLNV+VA+ ++++   
Sbjct: 206 LVMGNEGQGISPLMAESADQLVHISMKGQAESLNVAVAAGILIFHLS 252


>UniRef50_B5CKU5 Putative uncharacterized protein n=1 Tax=Ruminococcus lactaris ATCC
           29176 RepID=B5CKU5_9FIRM
          Length = 279

 Score =  173 bits (440), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 45/149 (30%), Positives = 73/149 (48%), Gaps = 3/149 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTHRT 78
            + ++ +  P N+  I RTA+A G   +        +    +  +  G+   +     + 
Sbjct: 132 VIVLDNLQDPGNLGTIFRTAEAAGATGILLSSDSVDVYNPKVIRSTMGAVFRMPFFYVKD 191

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           +  AV  L  QG++  A HL+   V + E DYT     L+G E  G+  E    AD  I 
Sbjct: 192 LPAAVKSLSSQGIRTYAAHLNGKNV-YDEEDYTEGCAFLIGNEGNGLRDEVSECADCLIR 250

Query: 139 IPMIGMVQSLNVSVASALILYEAQRQRQN 167
           IPM G  +SLN +VA+A++++EA RQR+ 
Sbjct: 251 IPMCGKAESLNAAVAAAVLMFEAGRQRRK 279


>UniRef50_A9KHD7 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Clostridium
           phytofermentans ISDg RepID=A9KHD7_CLOPH
          Length = 264

 Score =  173 bits (440), Expect = 4e-42,   Method: Composition-based stats.
 Identities = 43/149 (28%), Positives = 78/149 (52%), Gaps = 3/149 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTHRT 78
            + +E +  P N+  ++RTA+ VG+  +        M    +  +  G+   V       
Sbjct: 116 LLLLEDIRDPGNLGTMVRTAEGVGMTGIVLSKDSVDMFNPKVIRSTMGAIFRVPFFYAED 175

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
               +  +K + + I A HL   AV + ++ Y   + IL+G E  G++ +A +L+ Q I 
Sbjct: 176 FYACLNQIKNEEIAIYAAHL-QGAVWYDKVSYQGKSAILIGNEANGLSDKATSLSTQRIK 234

Query: 139 IPMIGMVQSLNVSVASALILYEAQRQRQN 167
           IPM G V+SLN ++A+A+++YE+ RQ +N
Sbjct: 235 IPMEGNVESLNAAIAAAVLMYESYRQIRN 263


>UniRef50_A5N255 Predicted methyltransferase n=28 Tax=Clostridium RepID=A5N255_CLOK5
          Length = 266

 Score =  173 bits (440), Expect = 4e-42,   Method: Composition-based stats.
 Identities = 40/173 (23%), Positives = 85/173 (49%), Gaps = 7/173 (4%)

Query: 2   NPTRYARIC---EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
           NP     +    E+  + +    +  +++  P N+  IIR+A A G   +        + 
Sbjct: 92  NPQGIIAVVKNKELNIKDEQGFYILADRIQDPGNMGTIIRSAHASGALGIITTKGTVDVY 151

Query: 59  T--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
                 A  GS  ++ +     +   V+ L+  G +++++ L D+ ++F ++D      I
Sbjct: 152 NEKTLRATMGSIFYIPIIQDENLEK-VSTLRQMGFKLISSSL-DSDINFYDMDLRGKIII 209

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
            +G E  G+ Q+   ++D ++ IPM G  +SLN +VA++++++E  RQ+ N+ 
Sbjct: 210 AIGNEGNGLLQDVKKISDIEVNIPMPGNAESLNAAVAASIMMFEVVRQKLNSH 262


>UniRef50_A1WUS8 RNA methyltransferase, TrmH family, group 3 n=8 Tax=Proteobacteria
           RepID=A1WUS8_HALHL
          Length = 271

 Score =  173 bits (439), Expect = 4e-42,   Method: Composition-based stats.
 Identities = 40/180 (22%), Positives = 76/180 (42%), Gaps = 30/180 (16%)

Query: 2   NPTRYA-RICEMLARRQPDLTVCMEQVHKPHNVSAIIRT---------------ADAVGV 45
            P R    + +++      L + +++V  PHN+ A +R+               A A+  
Sbjct: 98  TPARGEGELADLVDAEPEPLLLVLDRVQDPHNLGACMRSAAAAGAHGVVAPRDRAAAL-- 155

Query: 46  HEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDF 105
                         +   AAG+   +       +   +  L+  G+ ++     +     
Sbjct: 156 -----------SPAVHKTAAGAVQRIPFFQVTNLARTLQQLRDAGVHVVGAA-GEAEKSC 203

Query: 106 REIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            E+D   P  +++G E  G+ +      D+ + IPM G ++SLNVSVA+ ++L+EA RQR
Sbjct: 204 YEVDLRGPLALVLGGEGEGLRRLTRERCDERVAIPMPGSMESLNVSVAAGVLLFEAVRQR 263


>UniRef50_D0JB44 tRNA/rRNA methyltransferase n=2 Tax=Blattabacterium
           RepID=D0JB44_BLASB
          Length = 253

 Score =  173 bits (439), Expect = 5e-42,   Method: Composition-based stats.
 Identities = 46/174 (26%), Positives = 89/174 (51%), Gaps = 7/174 (4%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++P    +I ++L     + +  L V ++++    N  +IIRT+  VG   +      + 
Sbjct: 76  LSPIETYQIKDLLPVFYEKGKNPLLVILDRITDVRNFGSIIRTSACVGADAIIIPKKYTA 135

Query: 57  M--RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
           M        ++G+   V +   + I + +  L   G++I++     N + +  ID++ PT
Sbjct: 136 MIGSDSIKTSSGALFKVPICQEKNIKNTIEFLMNSGLKIVSATEKSN-IYWYNIDFSGPT 194

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
            +++G E+ GI+ + L ++ +   IP I  + SLNVSVA  +ILYE  RQR++ 
Sbjct: 195 ALILGNEEKGISPKYLEISCEKAKIPAIKGISSLNVSVACGVILYEVFRQRKSQ 248


>UniRef50_D0LZ96 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Haliangium
           ochraceum DSM 14365 RepID=D0LZ96_HALO1
          Length = 267

 Score =  173 bits (439), Expect = 5e-42,   Method: Composition-based stats.
 Identities = 48/163 (29%), Positives = 78/163 (47%), Gaps = 5/163 (3%)

Query: 4   TRYARICEMLA--RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT-- 59
             YA + +++A  R++P L V ++ V  PHN+ AI+R+A  +G   V      +   +  
Sbjct: 93  FEYAALEDLIAAPRQRPALFVALDSVTDPHNLGAIVRSAHVLGADGVILPKDRAAQVSGV 152

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
           +   +AG+   + +     +  A+  LK   + I      + A      D T   C+++G
Sbjct: 153 VTKVSAGATEQIAIAQVTNLARALEQLKQAEVWIAGLAAGEGATSLPAFDATGALCLVLG 212

Query: 120 QEKTGITQEALALADQDIIIPMIG-MVQSLNVSVASALILYEA 161
            E TG+        D  I IPM+G  V SLNVSVA+ + LYE 
Sbjct: 213 AEGTGLRPLVARTCDFLIEIPMLGAGVGSLNVSVAAGVALYEV 255


>UniRef50_D1J7J9 tRNA/rRNA methyltransferase n=2 Tax=Mycoplasma RepID=D1J7J9_MYCHP
          Length = 230

 Score =  172 bits (438), Expect = 5e-42,   Method: Composition-based stats.
 Identities = 41/168 (24%), Positives = 79/168 (47%), Gaps = 4/168 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP--GSRMR 58
           +   +Y  +  +  +   D  + ++ +  P N  AIIR+A+  G   +            
Sbjct: 64  LKDFQYHDLGSIF-KDGSDKVLILDHIQDPQNFGAIIRSANVFGFKHIIIPKDRACDVTP 122

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
           ++   ++G    V+V    ++ DA+  LK +G  I A+ L+  A    +  +     I++
Sbjct: 123 SVLKTSSGGFKNVKVIKVNSLFDAIEELKNKGFWIYASALNQQAKKLNDAKFNEKIAIIV 182

Query: 119 GQEKTGITQEALALADQDIIIPM-IGMVQSLNVSVASALILYEAQRQR 165
           G E +G+++  L  +D+ I I      VQSLNVSVA+ ++LY    ++
Sbjct: 183 GNEGSGVSKTLLKHSDEIIYIEQDKESVQSLNVSVATGILLYTVFNKK 230


>UniRef50_A8MI79 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Clostridiaceae
           RepID=A8MI79_ALKOO
          Length = 278

 Score =  172 bits (438), Expect = 6e-42,   Method: Composition-based stats.
 Identities = 40/158 (25%), Positives = 80/158 (50%), Gaps = 5/158 (3%)

Query: 8   RICEMLARRQPDLT-VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAA 64
            + E+ +++  +L  V ++++  P N+  IIRTA++     V                A 
Sbjct: 109 SLEEIKSQKGKELFFVILDRIQDPGNMGTIIRTAESANADAVIITKGSVDPYNSKTLRAT 168

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTG 124
            G+   + +         +  LK   ++++A  L  +   + +IDY     I++G E  G
Sbjct: 169 MGAIFHMPIIQCDD-DRWLDDLKENEVKLIAADLDTDKT-YIDIDYNTSIGIIIGNEANG 226

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
           I++  L+  DQ +IIP++G ++SLN SVA+++++Y+A 
Sbjct: 227 ISEALLSKVDQRVIIPILGKIESLNASVAASILIYKAA 264


>UniRef50_UPI0001C42339 RNA methyltransferase, TrmH family n=1 Tax=Bacillus pseudofirmus
           OF4 RepID=UPI0001C42339
          Length = 281

 Score =  172 bits (437), Expect = 8e-42,   Method: Composition-based stats.
 Identities = 46/166 (27%), Positives = 83/166 (50%), Gaps = 12/166 (7%)

Query: 2   NPTRYARICEMLARRQPDLT------VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS 55
            P   A +C + A   P +T      + +++V  P N+  +IRTADA G+  V       
Sbjct: 116 TPQGIAAVCAIPAP--PSMTTLSGQFLLIDRVQDPGNIGTMIRTADAAGMTGVVLGEGSV 173

Query: 56  RMRT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
            +    +  A+ GS   + V    ++ + V  LK + + +  T L++ +  +  I+    
Sbjct: 174 DLFNSKVIRASQGSIFHMPVIRG-SLIEWVEKLKEKNIPVFGTSLTEAS-SYTAIEPQPE 231

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILY 159
             +++G E  G+  E L  +DQ+I IP+ G  +SLNV+VA+ ++LY
Sbjct: 232 FALIVGNEGEGVQSELLEGSDQNIYIPIYGQAESLNVAVATGILLY 277


>UniRef50_C4V3B4 TrmH family rRNA methyltransferase n=2 Tax=Selenomonas
           RepID=C4V3B4_9FIRM
          Length = 276

 Score =  172 bits (437), Expect = 9e-42,   Method: Composition-based stats.
 Identities = 49/154 (31%), Positives = 78/154 (50%), Gaps = 3/154 (1%)

Query: 19  DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR--TMASAAAGSNSWVQVKTH 76
            L + +++V  P NV  I+RTADA G   V  +   + +    +  AA GS  ++   T 
Sbjct: 124 PLYLALDRVQDPGNVGTILRTADAAGASGVILLRGCADVYGSKVVRAAMGSLFYLPFVTG 183

Query: 77  RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQD 136
               D V   K   +   A     + V     + +RP+ +++G E  G+++  L  A Q 
Sbjct: 184 VDEEDLVRFAKENVLCFYAAACDTDGVTHFAAELSRPSLVVLGNEANGVSERLLR-AGQH 242

Query: 137 IIIPMIGMVQSLNVSVASALILYEAQRQRQNAGM 170
           + +PM G  +SLNV+ A+  ILYEA RQR+ AG+
Sbjct: 243 LYVPMCGRAESLNVAAAATAILYEAIRQRKYAGI 276


>UniRef50_Q7MTU3 RNA methyltransferase, TrmH family n=5 Tax=Bacteria
           RepID=Q7MTU3_PORGI
          Length = 249

 Score =  172 bits (437), Expect = 9e-42,   Method: Composition-based stats.
 Identities = 47/166 (28%), Positives = 81/166 (48%), Gaps = 4/166 (2%)

Query: 4   TRYARICEML-ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR--TM 60
           TR  ++  ML    +    + ++ +    N  AI RTA+  GV  +     GS       
Sbjct: 80  TRLDQLMPMLYEEGKAPFLLLLDGITDVRNFGAIARTAECAGVDAIIIPERGSVSVGGDA 139

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              +AG+   + V    +I  A+  L+  G++I+A      A  + ++    P  I+MG 
Sbjct: 140 IKTSAGALHRIPVCRVTSIPGAIRSLQEYGIRIVAAS-EKAADLYTDVPMKLPLGIVMGA 198

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           E  G + + L +AD  + IP +G + SLNVSVA+ +++YE  RQ++
Sbjct: 199 EDVGPSPDTLRMADGIVAIPQMGAIGSLNVSVAAGIVIYEVVRQQR 244


>UniRef50_C5WEU6 23S rRNA methyltransferase n=2 Tax=Firmicutes RepID=C5WEU6_STRDG
          Length = 245

 Score =  172 bits (437), Expect = 9e-42,   Method: Composition-based stats.
 Identities = 42/141 (29%), Positives = 70/141 (49%), Gaps = 3/141 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAGSNSWVQVKTHRT 78
            + +E V  P N+  IIRTADA G   V      + +       +  GS+  + +     
Sbjct: 103 YLILEDVQDPGNLGTIIRTADAAGFDGVFLSEKSADVYNSKTLRSMQGSHFHLPIWR-TD 161

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           I      ++     +LAT LS  +VD++ + +     ++MG E  GI+ E   LADQ + 
Sbjct: 162 IYKICREMQEHNTPVLATTLSKVSVDYKTVPHQESFALVMGNEGQGISAEMTTLADQLVH 221

Query: 139 IPMIGMVQSLNVSVASALILY 159
           I M G  +SLNV+VA+ ++++
Sbjct: 222 ITMPGQAESLNVAVAAGILIF 242


>UniRef50_C8W818 RNA methyltransferase, TrmH family, group 3 n=7
           Tax=Coriobacteriaceae RepID=C8W818_ATOPD
          Length = 338

 Score =  171 bits (435), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 43/170 (25%), Positives = 72/170 (42%), Gaps = 5/170 (2%)

Query: 3   PTRYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           P  YA + E++ R      L V ++ V    N  AI+R+A+ VG   V      +    +
Sbjct: 170 PFAYADLSEIIQRAGSANALVVVLDHVTDEGNFGAIVRSAEVVGAAGVVIANARAARVGV 229

Query: 61  A--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
                +AG+   + +     +  A+  LK  G     +          E        ++M
Sbjct: 230 GAYKTSAGAVLHLPIAQVSNLPRALEELKAAGFWTCGSTEHA-TQSVWEAPMGGRLALVM 288

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           G E +GI++  L   D    +P  G V+SLNV+ A+ ++ YE  R+ Q A
Sbjct: 289 GSEGSGISRLMLEKCDFTCKLPQFGQVESLNVAQATTVMCYEWLRRTQEA 338


>UniRef50_A5EVE3 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Dichelobacter
           nodosus VCS1703A RepID=A5EVE3_DICNV
          Length = 242

 Score =  170 bits (433), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 38/151 (25%), Positives = 70/151 (46%), Gaps = 3/151 (1%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSNSWVQVK 74
           +    + ++ +  PHN+ A +RTA A GV  V      +      +   A G+   + + 
Sbjct: 90  ERPFILVLDSIQDPHNLGACLRTAMAAGVDAVVLPNSCAADITPVVRKIACGAAEALAIF 149

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
               +   V  +K +G+ ++     +      ++D +    +++G E+ GI        D
Sbjct: 150 RVANLKREVEMMKEKGLWVVGGA-GEAEKSLFDLDLSGGLVMIVGNEEKGIHYGLRQTCD 208

Query: 135 QDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
               IPM   ++SLNVSVA  ++L+EA+RQR
Sbjct: 209 WLAAIPMAETMESLNVSVACGIMLFEARRQR 239


>UniRef50_Q2GL62 RNA methyltransferase, TrmH family, group 3 n=5 Tax=Anaplasma
           RepID=Q2GL62_ANAPZ
          Length = 258

 Score =  170 bits (433), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 38/157 (24%), Positives = 72/157 (45%), Gaps = 6/157 (3%)

Query: 8   RICEMLARRQP---DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MAS 62
           RI +++A+ +       + +++V   HNV A++RTA    V  V      S   +  MA 
Sbjct: 94  RIEDIVAQTEAAPTSTILVLDEVTDVHNVGAVLRTAACFNVDAVVLTEHNSPSESCGMAK 153

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
           A++G+   V V     +   + +LK +         S       +++++    +++G E 
Sbjct: 154 ASSGAIDIVPVVCIGNLVKTLEYLKQKNYWCYGFDASGG-TCLHQVEFSERRVVILGAEG 212

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILY 159
            G+        D  + IPM   ++SLNVS A+A+ +Y
Sbjct: 213 KGMRHLTKKHCDHLVKIPMSEKMESLNVSNAAAIAMY 249


>UniRef50_A4E9D9 Putative uncharacterized protein n=1 Tax=Collinsella aerofaciens
           ATCC 25986 RepID=A4E9D9_9ACTN
          Length = 302

 Score =  170 bits (432), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 45/176 (25%), Positives = 75/176 (42%), Gaps = 7/176 (3%)

Query: 4   TRYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA 61
             YA + ++L R    P L V ++ V    N  AI+R+A+ VG   V      +   T+ 
Sbjct: 130 FPYADVADILDRAGDGPALVVVLDHVTDDGNFGAIVRSAEVVGAAGVIIANKRAAGVTVG 189

Query: 62  --SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
               +AG+   + +     I  A+  LK  G  +             +  +     ++MG
Sbjct: 190 SYKTSAGAVMHLPIAQVPNIARALDDLKAAGFWVSGASERAEG-SCWDAPFEGRVALVMG 248

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLREN 175
            E  GI++  L   D    +P  GM +SLNV+ A+  + +E  R  +NAG  + E 
Sbjct: 249 SEGDGISRLVLEKCDFLTKLPQRGMTESLNVAQATTALCFEWLR--RNAGELMGEE 302


>UniRef50_C0X8M7 RNA methyltransferase n=36 Tax=Enterococcus RepID=C0X8M7_ENTFA
          Length = 258

 Score =  170 bits (432), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 38/141 (26%), Positives = 76/141 (53%), Gaps = 3/141 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTHRT 78
            + ++ +  P NV  +IRTADA G+  V      + +    +  +  GS+  + V   R 
Sbjct: 113 WLLLDNIQDPGNVGTMIRTADAAGLAGVILGKGTADIYNTKVLRSMQGSHYHLPVLQ-RE 171

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           + + V   K QG+ +  T L++ A+ + E +      +++G E +G++ E LA   +++ 
Sbjct: 172 LTEVVQAFKKQGLPVFGTELNEAAIAYYEQEAVENYALILGNEGSGVSPELLAETTKNLY 231

Query: 139 IPMIGMVQSLNVSVASALILY 159
           IPM G  +SLNV++A+ ++++
Sbjct: 232 IPMKGQAESLNVAIAAGVLMF 252


>UniRef50_Q8EPH3 rRNA methylase n=1 Tax=Oceanobacillus iheyensis RepID=Q8EPH3_OCEIH
          Length = 246

 Score =  170 bits (432), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 50/167 (29%), Positives = 81/167 (48%), Gaps = 7/167 (4%)

Query: 2   NPTRYARICEM---LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
            P     + EM     +   +L + ++ +  P N+  IIRTADA GV  V        + 
Sbjct: 82  TPQGVIAVVEMNIPKVQEDNNLIILLDAIQDPGNMGTIIRTADAAGVDAVVLGDGCVDIF 141

Query: 59  T--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
              +  A  GS   + + T  T+   +  L+ QG  ILAT L D AV++ E+       +
Sbjct: 142 NDKVIRATQGSIFHIPIYT-ATLEQEIHMLQTQGFTILATALHD-AVEYTEVSVHNKVGL 199

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           ++G E  GI    L  A+Q I IP+ G  +SLNV +A+ +++Y  ++
Sbjct: 200 ILGNEGAGIAPSLLNKANQRINIPIYGKAESLNVGIAAGILMYHLKK 246


>UniRef50_B0MYM4 Putative uncharacterized protein n=1 Tax=Alistipes putredinis DSM
           17216 RepID=B0MYM4_9BACT
          Length = 228

 Score =  170 bits (432), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 55/209 (26%), Positives = 98/209 (46%), Gaps = 5/209 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M+  R   +   L  R   +T+  E  +   N SA++R  +A GV ++H +    +    
Sbjct: 23  MSEERRQVLQRTLDSRTRYMTILTENTYHAQNASALVRHCEAFGVQDIHTIETRCKFNPN 82

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR-PTCILMG 119
            +   G++ W+ +  HRT  +A+A LKG+G +I+AT            D    P  ++ G
Sbjct: 83  VNIVRGTDKWIDLHRHRTTAEAIADLKGRGYRIVATTPHREDKTPETFDVAASPFVLVFG 142

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E  GI+ E +A AD+ + IPM GMV+SLNVS ++A+++Y    + +        +  L 
Sbjct: 143 TEHAGISDEIVAAADEFLRIPMCGMVESLNVSASAAILIYMLSSRMRE----TVPDWRLT 198

Query: 180 EAEQQRLLFEGGYPVLAKVAKRKGLPYPH 208
             ++  +L+   +  +          YP 
Sbjct: 199 AGKRAEILYRWTFASVRDAEAILRRKYPE 227


>UniRef50_C0QAQ0 SpoU n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QAQ0_DESAH
          Length = 291

 Score =  170 bits (432), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 37/145 (25%), Positives = 69/145 (47%), Gaps = 1/145 (0%)

Query: 19  DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHA-VWPGSRMRTMASAAAGSNSWVQVKTHR 77
           D  + ++ +    NV +I R+ DA G   +     PG     +   A G+  W+      
Sbjct: 133 DFHIALDGLRSLFNVGSIFRSCDAAGFSSLILGNTPGRENAAVRKTAMGTADWMPHTQTV 192

Query: 78  TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDI 137
            +   +  +K QG  I A   ++ +  + + D+     +++G E+ GI+   LA+ DQ +
Sbjct: 193 DLAQTLVDMKAQGYTITAVETAEQSKPYHDNDWHHRGVLVVGNEEYGISSHVLAVCDQVV 252

Query: 138 IIPMIGMVQSLNVSVASALILYEAQ 162
            IPM G   SLNV+ A+A++++   
Sbjct: 253 HIPMFGRKNSLNVANAAAILMFHIT 277


>UniRef50_Q1IND6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Candidatus Koribacter
           versatilis Ellin345 RepID=Q1IND6_ACIBL
          Length = 285

 Score =  170 bits (431), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 5/163 (3%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAA 65
           ++ ++L    P L      V  P N+  I+R+A+A G   V      +      +   ++
Sbjct: 126 KLEDLLRAENPMLLGVA-GVQDPGNLGTILRSAEAFGATGVLIGDKTASPWNPKVIRGSS 184

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           GS   + V        A+  L+ +G+QILAT          E+D+T PT +L+G E  G+
Sbjct: 185 GSVFRLPVVKVE-WPAALEQLRAKGVQILATSSHKGE-PLPEVDFTGPTIVLIGGEGAGV 242

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
            ++ LA  D  + IP    V+SLN  +A+++++YEA RQR   
Sbjct: 243 PRDVLASVDGTLAIPHSPKVESLNAGIAASIVMYEAARQRNTQ 285


>UniRef50_P94538 Uncharacterized tRNA/rRNA methyltransferase ysgA n=110
           Tax=Bacillales RepID=YSGA_BACSU
          Length = 248

 Score =  170 bits (431), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 44/165 (26%), Positives = 81/165 (49%), Gaps = 6/165 (3%)

Query: 2   NPTRYARICEMLARR--QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT 59
            P + A +C M   +       + ++ V  P N+  +IRTADA G+  V      +    
Sbjct: 85  TPQQIAAVCHMPEEKLATARKVLLIDAVQDPGNLGTMIRTADAAGLDAVVLGDGTADAFN 144

Query: 60  MA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
                +A GS+  + V   R +   V  LK +G+++  T L + A  ++EI  +    ++
Sbjct: 145 GKTLRSAQGSHFHIPVVR-RNLPSYVDELKAEGVKVYGTALQNGA-PYQEIPQSESFALI 202

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
           +G E  G+    L   D ++ +P+ G  +SLNV+VA+A+++Y  +
Sbjct: 203 VGNEGAGVDAALLEKTDLNLYVPLYGQAESLNVAVAAAILVYHLR 247


>UniRef50_C0W229 tRNA/rRNA methyltransferase n=2 Tax=Actinomyces RepID=C0W229_9ACTO
          Length = 322

 Score =  169 bits (430), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 4/163 (2%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAG 66
           +       Q  L V ++QV  PHN+ A++R+  A G+  V      S     A    +AG
Sbjct: 161 LERTKENAQIPLIVALDQVTDPHNLGAVLRSGGAFGITGVLISERRSASVNAAAWKVSAG 220

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDY-TRPTCILMGQEKTGI 125
           + + V V     +  A+  LK  G  ++        V  R++D  T P  ++ G E  G+
Sbjct: 221 AAARVPVARETNLVRALGELKEAGCFVVGLD-GGGDVSLRDLDLATGPLVVVTGAEGKGL 279

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           ++      DQ + IP+   V+SLN +VA+ + LYE   +R  A
Sbjct: 280 SRLVRETCDQIVSIPISSAVESLNAAVATGIALYEVASKRAEA 322


>UniRef50_C8NEH0 TrmH family RNA methyltransferase n=2 Tax=Granulicatella
           RepID=C8NEH0_9LACT
          Length = 256

 Score =  169 bits (430), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 41/141 (29%), Positives = 73/141 (51%), Gaps = 3/141 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTHRT 78
            + ++ V  P N+  I+RTADA G   V        +    +  +  GS+  + V     
Sbjct: 110 FIVLDAVQDPGNLGTIVRTADAAGFDAVVLGTGTVDLYNDKVLRSMQGSHFHIPVFQ-AN 168

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           + + +  LK +G+Q+  T L  ++ D+  +       I++G E  G++ + + LAD  + 
Sbjct: 169 LQEYLPILKEKGVQVAVTALHRDSKDYSVLQGATDVAIVVGNEGQGVSDDVIDLADVVVT 228

Query: 139 IPMIGMVQSLNVSVASALILY 159
           IP+ G  +SLNVS+ASAL++Y
Sbjct: 229 IPIFGKAESLNVSIASALLMY 249


>UniRef50_C7NJ34 rRNA methylase n=2 Tax=Micrococcineae RepID=C7NJ34_KYTSD
          Length = 271

 Score =  169 bits (430), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 61/165 (36%), Positives = 88/165 (53%), Gaps = 4/165 (2%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTM 60
           PT    + ++     P L V  E + KP N+ AI+RTADA GV  V A  P +      +
Sbjct: 107 PTPGVALADLPQPDGPGLYVVAEHLEKPGNLGAILRTADAAGVDAVIAADPVTDWGNPNV 166

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              + G+   V V T  T  + +  L G+GM ++AT      V   ++D T P  I +G 
Sbjct: 167 VRGSKGTVFSVPVATAPT-PEVLDFLAGRGMTLVATTPHTE-VLHTQVDLTGPVAIAVGA 224

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           EKTG+T  AL  A   + IPM+G   SLNV+ ++A+++YEA RQR
Sbjct: 225 EKTGLTASALEGATHRVRIPMVGRANSLNVATSAAIVVYEAVRQR 269


>UniRef50_Q6MA83 Putative rRNA methylase n=2 Tax=Chlamydiae/Verrucomicrobia group
           RepID=Q6MA83_PARUW
          Length = 265

 Score =  169 bits (430), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 52/171 (30%), Positives = 89/171 (52%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARICEM-LARRQP--DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM 57
           + P R+  + ++ L  ++P     V  E + KP N+  I+R++DAVG+  +      + +
Sbjct: 94  IAPQRHLTLDDLSLKTKKPMAPFFVVAEAIEKPGNLGTILRSSDAVGIDGLIVCDRCTDI 153

Query: 58  RT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
               +  A+ G+   V     R   D +  L  QG+ ILA        +F ++D T P  
Sbjct: 154 YNPNVVRASVGTLFTVPTVEARG-EDILLWLNKQGIDILAATPHAE-KEFTQVDLTSPVA 211

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           I +G E+ G+++  +  A   + IPM+G+  SLNV++A+ L+LYE  RQRQ
Sbjct: 212 IAVGTEQLGLSERWMKQATMQVRIPMMGVADSLNVAMATTLLLYEVLRQRQ 262


>UniRef50_C5SHP3 RNA methyltransferase, TrmH family, group 3 n=3
           Tax=Caulobacteraceae RepID=C5SHP3_9CAUL
          Length = 322

 Score =  169 bits (430), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 45/164 (27%), Positives = 69/164 (42%), Gaps = 10/164 (6%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAAG 66
           + E   R++  + V ++QV  P N+ AI+RT  A G   +      S +    +A  AAG
Sbjct: 155 LMEGALRQERPVLVMLDQVTDPQNIGAILRTCAAFGAAGLIMQDRHSPVMQGVLAKTAAG 214

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVD--------FREIDYTRPTCILM 118
           +   V       +  A+  L   G   L                  +R+    R   I+M
Sbjct: 215 AMDRVPFARVTNLSRALESLTENGFVSLGMAGEAEHSLQAVLEQQGWRQAGSPRALVIVM 274

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
           G E  G+ +      D  + IPM G  +SLNVS A+++ LYEA 
Sbjct: 275 GSEGEGLRRLVAEHCDHLVKIPMPGGFESLNVSHATSIALYEAL 318


>UniRef50_Q2S465 RRNA methylase n=1 Tax=Salinibacter ruber DSM 13855
           RepID=Q2S465_SALRD
          Length = 247

 Score =  169 bits (428), Expect = 8e-41,   Method: Composition-based stats.
 Identities = 57/187 (30%), Positives = 95/187 (50%), Gaps = 4/187 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP-GSRMRT 59
           M   R  RI  ++A R   +   +E +    NVSA++R+A+A+G  ++H V     R + 
Sbjct: 38  MRERRLDRIQTVVANRTRSVVPVVEGLVNTGNVSAVMRSAEALGHQDMHVVSGEHDRYKH 97

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
               A G+  W+ V           HL+  G +++A HL  + V  R++D+T+PT ++ G
Sbjct: 98  SQRTAQGAQHWLDVWHWDAPTACATHLQDAGYRVVAMHLHADTVPIRDLDFTQPTALVFG 157

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E  G+T   L  +D    +P+ G  +S NVSVA+A+ LY AQ+ R         ++ L 
Sbjct: 158 NEDAGVTDTMLEASDAACEVPLPGFTESFNVSVAAAVALYHAQQDRL---DRQGHHADLS 214

Query: 180 EAEQQRL 186
           +  + RL
Sbjct: 215 DEARARL 221


>UniRef50_B6YR56 23S rRNA (Guanosine-2'-O-)-methyltransferase n=1 Tax=Candidatus
           Azobacteroides pseudotrichonymphae genomovar. CFP2
           RepID=B6YR56_AZOPC
          Length = 274

 Score =  169 bits (428), Expect = 9e-41,   Method: Composition-based stats.
 Identities = 49/161 (30%), Positives = 81/161 (50%), Gaps = 4/161 (2%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAG 66
           +   L      L + +E + KP N+ AI+RTA+A  +       P + +    +  ++ G
Sbjct: 114 LLADLNLSNNPLIIVLESIEKPGNLGAILRTAEAAKIDATIICNPSTDIYNPNVVRSSIG 173

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
                 +       + +A+LK + +QI A  L+     +   D+T  + I++G E  G+T
Sbjct: 174 CLFSNPIAVASN-EETLAYLKSKSVQIFAAELTAFKQ-YYNTDFTSASAIVIGAEVNGLT 231

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
              L  A Q I IPM G++ SLNVSV+ A+I +EA RQR +
Sbjct: 232 NFWLDNAHQRIKIPMQGIIDSLNVSVSVAIITFEAIRQRNS 272


>UniRef50_Q09CR8 RRNA methylase n=2 Tax=Cystobacterineae RepID=Q09CR8_STIAU
          Length = 226

 Score =  169 bits (428), Expect = 9e-41,   Method: Composition-based stats.
 Identities = 52/205 (25%), Positives = 100/205 (48%), Gaps = 12/205 (5%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW-PGSRMRT 59
           +   R  +I  ++ +R    TV ++++    N++A++RT +A+GV EVH V  P +    
Sbjct: 22  LLDVRKEKIDRVVEQRTRTFTVVLDRLEDSFNMAAVLRTCEAMGVQEVHVVINPEAPFLP 81

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
            +  A G + W+ VK ++T  +   HL+ +G  + A+ + + A     + +     I+ G
Sbjct: 82  NSRVAQGCDKWLDVKLYKTFAECREHLQERGFALYASAIREGATSLYSMRFDSKVAIVFG 141

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR-----------QNA 168
            E+ G++++ LA  D    IPM G  QS+N+S A++  +      R           +  
Sbjct: 142 NERFGVSEDVLAGVDGTFWIPMRGFSQSINISAAASACVSRVMAWREEHLGKVGDLTEEE 201

Query: 169 GMYLRENSMLPEAEQQRLLFEGGYP 193
              LRE   +   +Q++ +F+G  P
Sbjct: 202 AQALRERFYVLALKQRKRIFKGKQP 226


>UniRef50_D0MG21 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Rhodothermus marinus DSM
           4252 RepID=D0MG21_RHOM4
          Length = 259

 Score =  169 bits (428), Expect = 9e-41,   Method: Composition-based stats.
 Identities = 61/187 (32%), Positives = 96/187 (51%), Gaps = 5/187 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR-T 59
           +   R  RI ++L  R   +   +E +    NVSA++R+A+A+G      +    +   T
Sbjct: 52  LTERRRQRIEQVLDGRTYTVVPVVEGLANTGNVSAVMRSAEALGYQGFGIIKGQVQKYKT 111

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
               A G++ W+ V T  T  +AV  LK  G +I+AT L + A      D+T PT ++ G
Sbjct: 112 SERTAQGADKWLDVWTWPTAAEAVPALKAAGYRIVATAL-EEAEPIDTFDFTVPTALVFG 170

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E  G+++E LA+AD   +IP++G  QS N+SVA+A+ LY AQR R         +  L 
Sbjct: 171 NEVEGVSRELLAMADARCVIPIVGFTQSFNISVAAAIALYHAQRDRLA---RRGRHGDLS 227

Query: 180 EAEQQRL 186
              +  L
Sbjct: 228 PEWKATL 234


>UniRef50_C0BGA8 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Flavobacteria
           bacterium MS024-2A RepID=C0BGA8_9BACT
          Length = 244

 Score =  169 bits (428), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 47/160 (29%), Positives = 72/160 (45%), Gaps = 3/160 (1%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAG 66
           I  +L  ++  + V ++ V    N  AI+R+A A GV  V     GS      +   +AG
Sbjct: 86  IESVLKEKENPVFVLLDGVTDTRNFGAILRSAAATGVDAVFISSTGSAPLNGDVVKTSAG 145

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
               V +   + + D V +LK   +  L      +     + D   P  ++ G E  GI+
Sbjct: 146 GAFKVPISKVQHLKDVVYYLKAHDIPTLGIT-EKSTETLYDSDLKGPLALVFGAEDVGIS 204

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
              L + D    +PM   V SLNVSVA A++ YE  RQR+
Sbjct: 205 NGLLKILDHKAKLPMTEAVDSLNVSVACAVVFYETIRQRR 244


>UniRef50_Q4A651 Putative tRNA/rRNA methyltransferase n=1 Tax=Mycoplasma synoviae 53
           RepID=Q4A651_MYCS5
          Length = 233

 Score =  168 bits (427), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 39/161 (24%), Positives = 77/161 (47%), Gaps = 3/161 (1%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTM 60
              Y+ I ++   + P + + ++ +   +N+ AIIR+A+A G+ ++             +
Sbjct: 68  DFTYSDINKIYESK-PKIVLVLDHIMDTYNLGAIIRSANAAGIKDIVMPKENCADITSNV 126

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              ++G    +      ++   +  LK     I  + L  N+  +    Y  P   ++G 
Sbjct: 127 LKVSSGGFIGINFYKVSSLNAFLNKLKKHSYWIYGSMLDKNSTSYYSAKYNFPMAFILGN 186

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEA 161
           E+ GI++ AL   D+ I IP  G V+SLNVSVA+ ++L++ 
Sbjct: 187 EEKGISKSALVEVDEKIHIPQSGSVESLNVSVAAGILLFDI 227


>UniRef50_A4XKC2 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Clostridia
           RepID=A4XKC2_CALS8
          Length = 271

 Score =  168 bits (426), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 44/170 (25%), Positives = 74/170 (43%), Gaps = 8/170 (4%)

Query: 2   NPTRYARICEMLAR-----RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
            P      C    +     ++ +  V ++ V  P N+  IIR ADA G   V  V     
Sbjct: 103 TPQGVLAECSFFDKELDVLKKHNRVVVIDSVQDPGNLGTIIRCADAFGFECVITVNGTVD 162

Query: 57  MRT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
           +    +  +A GS   V V   R   + +  L  +G  +  T    + VD  ++      
Sbjct: 163 VYNPKVVRSAMGSMFHVDVVRERKKEEVLEALNKRGFALYVTTPYGD-VDISKLSVDDRF 221

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            I++G E  G+    L  A + + I M G  +SLN +VA+A++LYE +++
Sbjct: 222 AIVIGNESKGVDVAFLENATKKVKISMPGKAESLNSAVAAAIVLYELRKK 271


>UniRef50_D0B4K6 tRNA/rRNA methyltransferase n=41 Tax=Rhizobiales RepID=D0B4K6_BRUME
          Length = 297

 Score =  168 bits (426), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 53/172 (30%), Positives = 84/172 (48%), Gaps = 12/172 (6%)

Query: 2   NPTRYARICEM-------LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG 54
           NP   A + E        L  +  D+ V +++V  P N+ A+IRTADAVG   V  +   
Sbjct: 119 NPQMVAGVFEQQYHQLAGLKPKGNDVYVALDRVRDPGNLGAVIRTADAVGAKGVILIGDT 178

Query: 55  SRMRTM--ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYT- 111
           +   ++    A  GS   V +    +  D +   KG    ++ THL   AVD+R I Y  
Sbjct: 179 TDPYSLETVRATMGSVFSVPLYR-ASEADFLNWRKGFSGLVVGTHL-KGAVDYRTIPYAN 236

Query: 112 RPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           +P  ++MG E+ G+        D+   IP  G   SLN+++A+ ++LYE +R
Sbjct: 237 KPVILIMGNEQQGLPDSLAGACDKLARIPQAGRADSLNLAIATGVMLYEIRR 288


>UniRef50_B7GPD2 RNA methyltransferase, TrmH family, group 3 n=4 Tax=Bifidobacterium
           longum RepID=B7GPD2_BIFLI
          Length = 333

 Score =  168 bits (426), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 42/191 (21%), Positives = 81/191 (42%), Gaps = 24/191 (12%)

Query: 1   MNPTRYARICEMLARRQ------------------PDLTVCMEQVHKPHNVSAIIRTADA 42
           ++P +Y+ + E+  R +                    L + ++ V  P N+ A+IR+A A
Sbjct: 143 VDPFQYSSLNELADRAEKKAKAMEAANSAAARIAARPLFIALDGVTDPQNLGAVIRSAAA 202

Query: 43  VGVHEVHAVWPGSRMRTMA----SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHL 98
            G + V    P  R  ++       +AG+ + + V     +  A+  LK +G  ++    
Sbjct: 203 FGANGVIL--PERRSASVNAAAWKVSAGAAAHMPVARVVNLTKALEGLKERGYYVVGLDG 260

Query: 99  SDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALIL 158
             + +       + P  +++G E +G+ +      D    IP+   V+SLN SVA+ + L
Sbjct: 261 GGDKLVGETGFESDPLVVVLGSEGSGLGRLVRETCDAIAGIPISSSVESLNASVAAGISL 320

Query: 159 YEAQRQRQNAG 169
           Y     R+ A 
Sbjct: 321 YAVSNARRKAA 331


>UniRef50_B9KYY7 RNA methyltransferase, TrmH family, group 3 n=4 Tax=Chloroflexi
           RepID=B9KYY7_THERP
          Length = 261

 Score =  168 bits (426), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 46/165 (27%), Positives = 80/165 (48%), Gaps = 2/165 (1%)

Query: 2   NPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRT 59
           +P  Y     +L      + + ++ +  P N++ ++RTA+A GV  V      +      
Sbjct: 83  SPYPYVDFATLLDPAPESIVLLLDHLQDPQNIATLLRTAEAAGVRGVVLPERRAAGITPA 142

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
           + +A+AG+   +Q+     +  AV  L+  G  I+A     NA          P  +L+G
Sbjct: 143 VVNASAGAVEHLQITLVTNLARAVDTLREHGYWIVALEPGPNAQSLFRAPLPLPLVLLVG 202

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            E  G++   L  AD  +IIPM+G ++SLN +VA ++ LYE  R+
Sbjct: 203 AEGHGLSPVLLKRADVQVIIPMLGQIESLNAAVAGSIALYEIVRR 247


>UniRef50_D1AU26 RNA methyltransferase n=1 Tax=Anaplasma centrale str. Israel
           RepID=D1AU26_ANACI
          Length = 262

 Score =  168 bits (426), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 38/145 (26%), Positives = 61/145 (42%), Gaps = 3/145 (2%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVK 74
                V ++QV   +NV AI+R+A    V  V      S      +   ++G+   V V 
Sbjct: 106 TASTVVLLDQVTDINNVGAIVRSAACFDVDAVILPEHHSPSENCIITRVSSGAADLVPVV 165

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
               +   + +LK  G       +  +     EI +     I++G E  GI +      D
Sbjct: 166 RVGNLVKTMEYLKQNGYWCYGMDVDGD-KALHEISFCERRAIILGSEGKGIRRLTREHCD 224

Query: 135 QDIIIPMIGMVQSLNVSVASALILY 159
             + IPM   + SLNVS A+A++LY
Sbjct: 225 HLVKIPMSARINSLNVSNAAAIVLY 249


>UniRef50_C2KTT3 TrmH family tRNA/rRNA methyltransferase n=2 Tax=Mobiluncus mulieris
           RepID=C2KTT3_9ACTO
          Length = 354

 Score =  167 bits (425), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 43/154 (27%), Positives = 74/154 (48%), Gaps = 8/154 (5%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA----SAAAGSNSWVQ 72
            P L V ++QV  PHN+ A++R+A A G   V  + P  R  ++       +AG+ + V 
Sbjct: 204 HPPLLVALDQVTDPHNLGAVLRSAAAFGADGV--IIPEHRAASVNAAAWKVSAGAAAIVP 261

Query: 73  VKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR-PTCILMGQEKTGITQEALA 131
           V     +  A+  LK  G  ++        V   ++  T  P  ++ G E  GI++    
Sbjct: 262 VAQATNLTRALQDLKRAGAFVIGLD-GGGDVALPDLQLTDVPLVVVTGSEGRGISRLVRD 320

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             DQ + IP+   ++SLN +VA+ + LY+   +R
Sbjct: 321 TCDQIVSIPIAPRMESLNAAVATGIALYQIAVRR 354


>UniRef50_A0LPE7 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Syntrophobacter
           fumaroxidans MPOB RepID=A0LPE7_SYNFM
          Length = 252

 Score =  167 bits (425), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 44/169 (26%), Positives = 78/169 (46%), Gaps = 5/169 (2%)

Query: 1   MNPTRYARICEMLARR--QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS--R 56
           M    YA +  +L +   + +  V ++ +  P N+ A++R+A  +G   V      S   
Sbjct: 81  MREFPYAALEALLEKPTGEREPLVILDCLQDPQNLGAMLRSACFLGARGVIVPRDRSARV 140

Query: 57  MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
             T+   AAG+ +++ V     +  A+  LK  G+ I     +  A    + D T P  +
Sbjct: 141 TSTVIRIAAGATAYLPVIQVNNLVRALEQLKECGLWIFGLD-AQAAQTIYDADLTVPLGL 199

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           ++G E+ G+        D  + IP  G +QSLN + + A+ L E QR+R
Sbjct: 200 VVGNEQKGLRPLVARACDAMVRIPEHGPLQSLNAATSGAIALAEVQRRR 248


>UniRef50_O30272 Uncharacterized tRNA/rRNA methyltransferase AF_2399 n=2
           Tax=Archaeoglobaceae RepID=Y2399_ARCFU
          Length = 224

 Score =  167 bits (425), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 45/171 (26%), Positives = 77/171 (45%), Gaps = 10/171 (5%)

Query: 1   MNPTRYARICEMLARR--QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
           ++P +YA    ++ +        + ++ V    N+ A IRTA+  G   V  V P  R+ 
Sbjct: 57  VSPIKYADFEFIVKKALTGGSFILFLDNVVDQRNIGACIRTAEFFGAAGV--VLPKRRVG 114

Query: 59  TM----ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
           ++      A+AG+   + +        A+  LK  G   LA  L     D   +    P 
Sbjct: 115 SIQEGAVKASAGAVFHIPIARVENFASAIKKLKKLGFTTLAADLDGE--DLEAVSLLLPA 172

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            +++G E  G+++      D  + IP +G V SLN+SVA+ + LY   RQ+
Sbjct: 173 AVVIGGEDRGVSRPVKKQCDFVVKIPGVGKVNSLNLSVAAGIFLYTLSRQK 223


>UniRef50_Q03G93 rRNA methylase n=1 Tax=Pediococcus pentosaceus ATCC 25745
           RepID=Q03G93_PEDPA
          Length = 255

 Score =  167 bits (424), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 40/141 (28%), Positives = 73/141 (51%), Gaps = 3/141 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAGSNSWVQVKTHRT 78
            + ++ V  P N+  ++RTADA G   V      +         A  GS   +Q+K    
Sbjct: 112 WLVLDNVQDPGNIGTMVRTADAAGFTGVVFGDGTADFYNPKILRAMQGSQYHLQLKRL-N 170

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           +   + + K QG  I  + L +NA D+R+ID      ++MG E  G+++  + + D ++ 
Sbjct: 171 LEKWIRNCKDQGSVIFGSILDENARDYRKIDVPDQFSLIMGNEGNGMSERLIEMTDMNLY 230

Query: 139 IPMIGMVQSLNVSVASALILY 159
           IP+ G  +SLNV+VA+ ++++
Sbjct: 231 IPIKGSAESLNVAVAAGVLMF 251


>UniRef50_A9WLY5 23S rRNA methyltransferase TrmH, group 3 n=11 Tax=Actinobacteria
           (class) RepID=A9WLY5_RENSM
          Length = 336

 Score =  166 bits (422), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 43/163 (26%), Positives = 69/163 (42%), Gaps = 3/163 (1%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSNSWVQV 73
           +   L V ++ +  P N+ AIIR+  A     V      S     +    +AG+   V V
Sbjct: 173 KNSPLIVALDGITDPRNLGAIIRSVSAFAGQAVIVPERRSVGLTASAWKTSAGAAVRVPV 232

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALA 133
                +  A+   KG G  +L      +           P CI++G E  G+++      
Sbjct: 233 ARAGNLNRALESFKGMGYFVLGLDGDGDVSLPALAVAKEPVCIVVGSEGKGLSRLVRENC 292

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENS 176
           DQ + IP+   ++SLN S+A  + LYE  RQR + G   + N 
Sbjct: 293 DQIVSIPIDSAMESLNASMAVGITLYEIARQR-SGGSAEQGNP 334


>UniRef50_B0MRI6 Putative uncharacterized protein n=1 Tax=Eubacterium siraeum DSM
           15702 RepID=B0MRI6_9FIRM
          Length = 262

 Score =  166 bits (422), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 36/148 (24%), Positives = 69/148 (46%), Gaps = 4/148 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAAGSNSWVQVKTHRT 78
            + +E +    N+  IIR+ DA  +  V      + +       +A GS   + +     
Sbjct: 117 FIILENLQDMGNIGTIIRSCDAFSIDGVILAGDCADVFAPKTVRSAMGSLFRLPIYCC-D 175

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
             +A+  L+  G  + +  LSD +V   E    + T +++G E  G++     L D+ + 
Sbjct: 176 TEEAITLLQKGGFTVYSAELSDRSVRLGEEKLPQKTAVVIGNEGNGVSDTVKKLCDKSLF 235

Query: 139 IPMIGMVQSLNVSVASALILYEAQRQRQ 166
           IP+    +SLN SVA+++I +E  + R+
Sbjct: 236 IPIS-SAESLNASVAASVIAWEMSKVRE 262


>UniRef50_D2RCJ3 RNA methyltransferase, TrmH family, group 3 n=14
           Tax=Actinobacteridae RepID=D2RCJ3_GARVA
          Length = 331

 Score =  166 bits (422), Expect = 5e-40,   Method: Composition-based stats.
 Identities = 43/190 (22%), Positives = 79/190 (41%), Gaps = 20/190 (10%)

Query: 1   MNPTRYARICEMLARRQ------------------PDLTVCMEQVHKPHNVSAIIRTADA 42
           + P +Y  + E++ R +                    L + ++ V  P N+ A+IR+A A
Sbjct: 139 VQPYQYHSLQELVERAEKKARAMEAADSDSARINARPLFIALDGVTDPQNLGAVIRSAAA 198

Query: 43  VGVHEVHAVWPGSRMRTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSD 100
            G + V      S   T A    +AG+ + + V     +  A+  L+ +G   +      
Sbjct: 199 FGANGVILPERRSASVTAAAWKVSAGAAAHLPVARVVNLNKAIQGLRERGWYAIGLDGGG 258

Query: 101 NAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYE 160
           + +       T P  +++G E  G+++      D    IP+   V+SLN SVA+ + LY 
Sbjct: 259 DKLVGETGFETDPLVVVLGSEGKGMSRLTREACDAIAGIPISSAVESLNASVAAGISLYA 318

Query: 161 AQRQRQNAGM 170
               R+ A +
Sbjct: 319 VANARRLAAL 328


>UniRef50_A4S6N6 Predicted protein (Fragment) n=1 Tax=Ostreococcus lucimarinus
           CCE9901 RepID=A4S6N6_OSTLU
          Length = 216

 Score =  166 bits (422), Expect = 5e-40,   Method: Composition-based stats.
 Identities = 56/187 (29%), Positives = 89/187 (47%), Gaps = 5/187 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS-RMRT 59
           +   R  R+  +L  R   L   +E V+   N+ A+ RT +A+G+     V       + 
Sbjct: 27  VGEERRMRLENVLEHRSFSLLPILEGVYDVGNILAVCRTTEALGIGCASIVSSKGLSFKA 86

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
               + G+  W  V+   T   A+   K +G ++L T   D A      D+T PT ++ G
Sbjct: 87  SGRTSGGALKWQHVEQFETSERALRVAKAKGYRVLTTEF-DGAQPLSHYDWTVPTAVVFG 145

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E+ G++ EA AL D  + IPM G  +SLN+SVA+AL++  A   R N       +  L 
Sbjct: 146 NEREGVSDEARALRDGAVYIPMFGFTESLNISVAAALVMSHAVTDRIN---RRGFHGDLT 202

Query: 180 EAEQQRL 186
           E E++ L
Sbjct: 203 EEEKRIL 209


>UniRef50_C7PMX4 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Chitinophaga
           pinensis DSM 2588 RepID=C7PMX4_CHIPD
          Length = 263

 Score =  166 bits (422), Expect = 5e-40,   Method: Composition-based stats.
 Identities = 40/159 (25%), Positives = 73/159 (45%), Gaps = 3/159 (1%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAG 66
           I  +  + Q  L + ++ +    N+ AI R+A   G   +     G          ++AG
Sbjct: 104 ISHVTEQGQTPLFLILDGITDVRNIGAIARSAVCCGAQAIIIPDRGIAALNEEAIKSSAG 163

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           +   + V    ++  A+  L   G++++A+ + +      +     P  ++MG E  G+ 
Sbjct: 164 ALETISVCRVNSLLKAIDTLHLNGIKVIASEM-EAETKLYDCQLQEPVAVIMGSEDKGVF 222

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
              +  +D    IPM G  +S NVSVA+ +ILYEA +QR
Sbjct: 223 PALIKASDTLFHIPMAGNFESFNVSVAAGIILYEAMKQR 261


>UniRef50_B2GD96 rRNA methylase n=26 Tax=Bacilli RepID=B2GD96_LACF3
          Length = 259

 Score =  166 bits (422), Expect = 5e-40,   Method: Composition-based stats.
 Identities = 38/144 (26%), Positives = 70/144 (48%), Gaps = 3/144 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAAGSNSWVQVKTHRT 78
            + +++V  P NV  ++RTADA G   V A    + +    +  +  GS   + +     
Sbjct: 112 WLFLDRVQDPGNVGTMVRTADAAGFAGVVAGDGSADLFSPKVVRSMQGSQFHLALYEG-D 170

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           +      +K  G  +  T L+  A DFR +       ++MG E  G+++E L     ++ 
Sbjct: 171 LKKWFEDVKQAGYPVYGTQLNPAAKDFRIVTPQGGFALVMGNEGRGMSEELLKQTTANLY 230

Query: 139 IPMIGMVQSLNVSVASALILYEAQ 162
           IPM G  +SLNV+V++ ++++E  
Sbjct: 231 IPMRGQAESLNVAVSAGILMFELA 254


>UniRef50_B0PD55 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
           DSM 17241 RepID=B0PD55_9FIRM
          Length = 264

 Score =  166 bits (421), Expect = 6e-40,   Method: Composition-based stats.
 Identities = 42/172 (24%), Positives = 74/172 (43%), Gaps = 9/172 (5%)

Query: 1   MNPTRYARICEMLARRQPDL-------TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP 53
           ++P     +  ML  R   +        + +  +  P NV  I+RTA A G   V     
Sbjct: 93  VSPQGVFGVFMMLDNRTQPVKIGSNGKYLLLSSLQDPGNVGTILRTAAAFGTDGVILSAD 152

Query: 54  GSRMR--TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYT 111
              +    +  A+ G     +      +  ++A L+  G+ + A   ++ +V  R+I   
Sbjct: 153 CPDLYAPKVLRASMGGVFRARACVSDDLSASIAALRAAGVPVWAAMPAEGSVSLRDISLH 212

Query: 112 RPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
               +++G E  GI  E  AL D  + IPM    +SLN ++A+ +IL+E  R
Sbjct: 213 GGGAVVVGNEGGGIAPELAALCDGALTIPMEPGCESLNAAMAAGVILWEMYR 264


>UniRef50_A8S2F6 Putative uncharacterized protein n=8 Tax=Clostridiales
           RepID=A8S2F6_9CLOT
          Length = 270

 Score =  166 bits (421), Expect = 6e-40,   Method: Composition-based stats.
 Identities = 41/150 (27%), Positives = 78/150 (52%), Gaps = 3/150 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTHRT 78
            + +E +  P N+  IIR  +  G+  +      + +    +  +  GS   +       
Sbjct: 115 IMVLETIQDPGNLGTIIRAGEGAGITGIVMNHDTADIYNPKVIRSTMGSIFRMPFVYADD 174

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           + DA   +K +G+++ A HL     ++ + DYT     L+G E  G+T+E  +LAD  + 
Sbjct: 175 LQDACLLMKNRGVRLFAAHL-KGMNNYDQEDYTDNVGFLIGNEANGLTEETTSLADCLVK 233

Query: 139 IPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           IPM G V+SLN ++A++++++E  RQR++ 
Sbjct: 234 IPMEGKVESLNAAIAASVLMFETARQRRSC 263


>UniRef50_Q11C30 tRNA/rRNA methyltransferase (SpoU) n=21 Tax=Alphaproteobacteria
           RepID=Q11C30_MESSB
          Length = 286

 Score =  165 bits (420), Expect = 8e-40,   Method: Composition-based stats.
 Identities = 50/163 (30%), Positives = 83/163 (50%), Gaps = 6/163 (3%)

Query: 4   TRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM--A 61
            R+  + E+  + + DL V +++V  P N+  IIRT DAVG   V  V   +   ++   
Sbjct: 116 QRWLPLKEVTPKGE-DLWVALDRVRDPGNLGTIIRTVDAVGARGVILVGECTDPFSVETV 174

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR-PTCILMGQ 120
            A  GS   V +         +A  +     ++ THL   +VD+R +DY+  P  +LMG 
Sbjct: 175 RATMGSVFSVPLAR-ADEAAFLAWREHFAGLMVGTHL-KGSVDYRNVDYSGGPVLLLMGN 232

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           E+ G+  +     D+ + IP  G   SLN++VA+ ++LYE +R
Sbjct: 233 EQQGLPDKLAEACDRLVRIPQAGRADSLNLAVATGVMLYEIRR 275


>UniRef50_A7VXH5 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VXH5_9CLOT
          Length = 270

 Score =  165 bits (420), Expect = 8e-40,   Method: Composition-based stats.
 Identities = 41/179 (22%), Positives = 82/179 (45%), Gaps = 9/179 (5%)

Query: 1   MNPTRYARICEMLAR-------RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP 53
           + P     +C ML +             + +E +  P N+  ++RTA+A+G+  V     
Sbjct: 92  VTPQGIFCVCAMLDKTDCLDKMDASGQLLGLEDIQDPSNLGTVLRTAEALGIGGVILTRG 151

Query: 54  GSRMR--TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYT 111
              +    +   + G+   + +    T+  AV  L+ +G   +A      A    ++ ++
Sbjct: 152 CCDIYSPKVLRGSMGAVFRLPMALVETMPPAVNALEQKGFVTMAAVPDREAEPITQVLFS 211

Query: 112 RPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGM 170
            P+ +L+G E  G+  E +    + + IPM+G  +SLN SVA++L+++E  R    A +
Sbjct: 212 SPSIVLVGNEGNGLKPETIRACQRRVTIPMLGRAESLNASVAASLLMWEMMRASGEAAL 270


>UniRef50_Q04SA9 TRNA (Guanosine-2'-O-)-methyltransferase n=4 Tax=Leptospira
           RepID=Q04SA9_LEPBJ
          Length = 253

 Score =  165 bits (420), Expect = 8e-40,   Method: Composition-based stats.
 Identities = 40/164 (24%), Positives = 82/164 (50%), Gaps = 9/164 (5%)

Query: 2   NPTR-----YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           +P R        + E L+ + P   + ++++  P N+  I+RTA+  GV  +      S 
Sbjct: 85  SPFRQQISDKKNLEEYLSEK-PGTFLVLDRIQDPGNLGNILRTAECFGVTNIILPERESA 143

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
                +   ++G+ S++++ T + + + +  LK  G  I++T       ++ ++   +  
Sbjct: 144 GITPVVEKVSSGALSFLKIFTVKNLANTLELLKENGYWIVSTS-DRGTENWSKLPELKEL 202

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALIL 158
            ILMG E  G+ +  L  +D  + IP+ G + SLNV+VA+ ++L
Sbjct: 203 AILMGNEGEGVKRILLEKSDFVLRIPIHGNLSSLNVTVATGIVL 246


>UniRef50_Q2ST10 RNA methyltransferase, TrmH family, group 3 n=5 Tax=Mollicutes
           RepID=Q2ST10_MYCCT
          Length = 244

 Score =  165 bits (419), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 38/161 (23%), Positives = 80/161 (49%), Gaps = 2/161 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MR 58
            N T +  +   L  ++  L + ++Q+H P+N  AIIR+   + V  +  +         
Sbjct: 74  FNYTPFDELLNDLNTKEKSLVLVLDQIHDPYNFGAIIRSCSLLNVDGIIILDKKQVQVNS 133

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
           T+   ++GS   +++     + +A+  LK  G  I AT+L+ N+ D  +  +   + +++
Sbjct: 134 TVLKTSSGSAFDIKISKTNNLNNAIKILKNNGFWIYATNLNQNSTDMTKTQFANKSVVII 193

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILY 159
           G E+ G+++     +D +I +P    + S N SVA ++I +
Sbjct: 194 GNEQKGVSELLTKNSDFNIYVPSNKNIDSFNASVACSIICF 234


>UniRef50_A8DJH5 TsnR n=1 Tax=Candidatus Chloracidobacterium thermophilum
           RepID=A8DJH5_9BACT
          Length = 282

 Score =  165 bits (419), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 47/162 (29%), Positives = 79/162 (48%), Gaps = 8/162 (4%)

Query: 13  LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAGSNSW 70
           L      L V  + +  P N+ A+IRTA+A G   +                AAAGS   
Sbjct: 110 LTHHPAPLFVLADGIQSPGNLGALIRTAEAAGATGILVTVGTVDPFQPKALRAAAGSAFR 169

Query: 71  VQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEA- 129
           + +    ++ D +  L  QG++++   +  +   +   D+ +P  + +G E  G+     
Sbjct: 170 LPIIAGSSVADELQKLYRQGVRLVTADIHGD-TPYEAFDWRQPVLLWLGSEGHGLRSLTD 228

Query: 130 ---LALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
                LA + + IPM G V+SLNV+VA A++LYEA+RQR+ +
Sbjct: 229 DFKHRLAARLV-IPMEGQVESLNVAVAGAILLYEARRQRRQS 269


>UniRef50_C9XLS4 Putative RNA methylase n=9 Tax=Clostridium RepID=C9XLS4_CLODC
          Length = 265

 Score =  165 bits (419), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 37/161 (22%), Positives = 82/161 (50%), Gaps = 3/161 (1%)

Query: 4   TRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASA 63
            +  ++ E + ++     + ++++  P N+  IIRTAD+ GV  + A+     +      
Sbjct: 104 FKKKKLSESINKKDK-FVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPKVI 162

Query: 64  AAGSNSWVQVKTHR-TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
            +   S   +     +  + V  LK     I++++L+     + +IDY     +++G E 
Sbjct: 163 RSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENF-YDKIDYGSKVALVIGNEA 221

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
            GI +E ++ +D  + IP+ G  +SLN +++SA+++YE ++
Sbjct: 222 NGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKK 262


>UniRef50_C1E8J5 Predicted protein (Fragment) n=3 Tax=Mamiellales RepID=C1E8J5_9CHLO
          Length = 234

 Score =  165 bits (418), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 56/204 (27%), Positives = 104/204 (50%), Gaps = 6/204 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP-GSRMRT 59
           ++  R AR+  ++ +R  DL   +E V+   NV A+ R+ +A+G+  +  +   G   + 
Sbjct: 28  VSEERIARLDAVVQQRSFDLMPILEGVYDIGNVLAVCRSTEALGIGSLGVISDAGLAFKQ 87

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
               + G+  W  ++  R+  +A+  +K +G ++L T + +        D+T PT +++G
Sbjct: 88  SGRTSGGAVKWTNLEQWRSTEEAIREVKARGYRVL-TTVFEGGHPLEHYDWTVPTAVILG 146

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E+ G++ EA  LAD  + I M G  +SLNVSVAS++I++ A + R      L  +  L 
Sbjct: 147 NERDGVSDEAKRLADGGVYISMNGFTESLNVSVASSMIMHHAVQDRTR---RLGSHGNLS 203

Query: 180 EAEQQRLLFEGGYPVLAKVAKRKG 203
           E E++ L        L    ++ G
Sbjct: 204 EREKETLRAVYL-ARLVPRYQKHG 226


>UniRef50_B5YIM1 RNA methyltransferase, TrmH family n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YIM1_THEYD
          Length = 261

 Score =  165 bits (418), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 47/172 (27%), Positives = 77/172 (44%), Gaps = 9/172 (5%)

Query: 1   MNPTRYARICEMLARR-----QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS 55
           + P     I +   +       P   V  +++  P N+  IIR A+A G   V       
Sbjct: 87  VTPQGVFAIADFKIKNINDLSNPTFIVIADRIQDPGNIGTIIRAAEAFGAEAVLVTHGTC 146

Query: 56  RMRTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
              +     A+AGS  ++ V    T+ +    +   G+ ++ T L      F  +D+T+P
Sbjct: 147 NPFSNKALRASAGSIFFLPVIKV-TVKEIEEFVSKYGLNLVITDLKATISSF-NMDFTKP 204

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             I+ G E  G++Q+  A+      IP  G  +SLNV++A+  ILYE  RQR
Sbjct: 205 LAIVFGNESKGVSQDLRAIKHTSCKIPHKGKAESLNVAMAATAILYEILRQR 256


>UniRef50_C7M4Y5 tRNA/rRNA methyltransferase (SpoU) n=13 Tax=Bacteroidetes
           RepID=C7M4Y5_CAPOD
          Length = 267

 Score =  165 bits (418), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 49/152 (32%), Positives = 83/152 (54%), Gaps = 4/152 (2%)

Query: 18  PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAGSNSWVQVKT 75
             L +  E   KP N+ A++RTADA  +  V    P + +       ++ G    V + T
Sbjct: 116 SPLLLVAEAPEKPGNIGALLRTADAANIDAVIIANPKTDLYNPNIIRSSVGCVFTVPIAT 175

Query: 76  HRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQ 135
             T  + +  LK +G+      L+     + E+ +   + I++G E  G+T+E L  + Q
Sbjct: 176 GSTT-EVIDFLKAKGINSYCAALTAF-KPYYEVSFEEASAIVVGTEDQGLTEEWLTHSTQ 233

Query: 136 DIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           +IIIPM G++ S+NVSVA+A++++EA+RQR N
Sbjct: 234 NIIIPMEGVIDSMNVSVAAAVLIFEAKRQRVN 265


>UniRef50_B2KBE6 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Elusimicrobium
           minutum Pei191 RepID=B2KBE6_ELUMP
          Length = 249

 Score =  165 bits (418), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 39/168 (23%), Positives = 81/168 (48%), Gaps = 8/168 (4%)

Query: 1   MNPTRYARICEMLA---RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           + P +  R+ + +      + DL + ++++  P N+ +IIR+A  +G   +      +  
Sbjct: 78  VEPVKIMRLIDAIDVSRGNKKDLWIAVDEMTDPQNLGSIIRSAACLGFSTIILPSRRTVG 137

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              ++   A+G+   V V     +  A+  LK +G  I    +   ++   + DY+ P  
Sbjct: 138 LTPSVYKVASGATEKVTVVEVANLATALLDLKDEGFWIYGADMGGQSIV--KTDYSFPAV 195

Query: 116 ILMGQEKTGITQEALALADQDIIIPM-IGMVQSLNVSVASALILYEAQ 162
           +++G E TGI ++     DQ + IP   G V SLN + A+++I+++  
Sbjct: 196 LVVGSEGTGIREKTAEHCDQVVSIPQAPGSVDSLNAANAASIIMFDMF 243


>UniRef50_B9E768 rRNA methyltransferase homolog n=1 Tax=Macrococcus caseolyticus
           JCSC5402 RepID=B9E768_MACCJ
          Length = 246

 Score =  165 bits (418), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 43/165 (26%), Positives = 76/165 (46%), Gaps = 9/165 (5%)

Query: 3   PTRYARICEMLARRQPDL--TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT- 59
           P     +C M   +  +L   + ++++  P NV  IIRTADA G+  V        +   
Sbjct: 87  PQGIYAVCNMKDGKDAELNRVIYLDRIQDPGNVGTIIRTADAAGLDAVIIAKGTVDIYND 146

Query: 60  -MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
            +  A+ GS   + V       D           I  T L + A D++E+  +    I++
Sbjct: 147 KVLRASQGSVFHIPVIE----MDFDEVSSKFNGTIYGTSL-EEARDYKEVIPSDNFMIVL 201

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           G E  G+  E L+  D+++ IP+ G  +SLNV+V + +++Y   +
Sbjct: 202 GNEGQGVNPEILSATDENLYIPIYGRAESLNVAVCAGILMYHFVK 246


>UniRef50_B9Y9V6 Putative uncharacterized protein n=1 Tax=Holdemania filiformis DSM
           12042 RepID=B9Y9V6_9FIRM
          Length = 244

 Score =  164 bits (417), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 5/145 (3%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTHRT 78
           TV ++ V  P NV  IIRTA A G  +V      + +       +  G+   + +     
Sbjct: 101 TVVLDGVQDPGNVGTIIRTAVAFGFDQVLLSPDCADVYNEKCVRSTQGALFHIAISR-TE 159

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           +  A+  LK  G+ ++ T L   A    E+  +    +++G E  GI    L + DQ  +
Sbjct: 160 LIPALNELKELGVTVIGTAL-QGAQPLSELPVSENIAVVLGNEGQGIRPATLDICDQRAL 218

Query: 139 IPMIGMVQSLNVSVASALILYEAQR 163
           I M    +SLNV+VA+ + LY  +R
Sbjct: 219 IEMS-SFESLNVAVAAGICLYRYRR 242


>UniRef50_UPI0001BC4585 23S rRNA methyltransferase n=1 Tax=Fusobacterium sp. D12
           RepID=UPI0001BC4585
          Length = 224

 Score =  164 bits (417), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 36/141 (25%), Positives = 71/141 (50%), Gaps = 3/141 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTHRT 78
            + ++ +  P N+  +IR  DA G  ++             +  ++ GS   V++     
Sbjct: 75  LIVLDDIQDPGNLGTMIRLVDAAGFSDIFLTKHSVDCYNEKVVRSSMGSIFHVRLHVMEK 134

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
             + + +L+ +   +L T L  ++V + E+        + G E  G+++E L LA+Q II
Sbjct: 135 -KEILEYLQTENYHVLVTTLQRDSVAYTEMQLKEKNAFVFGNEGHGVSKEFLELAEQKII 193

Query: 139 IPMIGMVQSLNVSVASALILY 159
           IP+ G  +SLNV++A+ +IL+
Sbjct: 194 IPISGQAESLNVAMAAGIILF 214


>UniRef50_B7C827 Putative uncharacterized protein n=1 Tax=Eubacterium biforme DSM
           3989 RepID=B7C827_9FIRM
          Length = 244

 Score =  164 bits (417), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 33/141 (23%), Positives = 75/141 (53%), Gaps = 4/141 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMAS--AAAGSNSWVQVKTHRT 78
            + ++ V  P NV  I+RTA + G+  ++     + +    +  ++ G+  ++ V     
Sbjct: 99  ILLLDNVQDPGNVGTILRTAHSFGIDCIYMSKGCADIYNPKTIQSSQGALFYIPVIQ-TD 157

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           + + +  L+ + +++ AT L D   D ++I  ++   IL+G E  G+ +E + L++  + 
Sbjct: 158 LVEEIKKLQERNIEVYATALHDKHKDLQDIKPSKKYAILVGNEGQGVRKELIDLSNHIVK 217

Query: 139 IPMIGMVQSLNVSVASALILY 159
           I M    +SLNV++A+++ +Y
Sbjct: 218 IEME-TFESLNVAIATSICMY 237


>UniRef50_D2R0C4 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Pirellula staleyi DSM
           6068 RepID=D2R0C4_9PLAN
          Length = 272

 Score =  164 bits (417), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 55/160 (34%), Positives = 88/160 (55%), Gaps = 4/160 (2%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAG 66
           + + LA ++  L   +E V KP N+ AI+R+ADA G+  V        +       A+ G
Sbjct: 113 LQDKLAAKRDLLVAVVEGVEKPGNLGAILRSADAAGIDGVIVCGARLDLYNPNAIRASLG 172

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           +   + V    T+  A+A L+    Q+LAT + D A+D+   D    T I++G E  G++
Sbjct: 173 ALFTLPV-IGMTVPQALAWLRMHQFQMLATRV-DGAIDYTTADLRGRTAIILGSEAEGLS 230

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           +E L    + I +PM+G V SLN+SV +A++ YEA RQR+
Sbjct: 231 REWLGDDIRAISLPMLGTVDSLNLSVTAAILFYEALRQRR 270


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_P0AGJ3 tRNA guanosine-2'-O-methyltransferase n=231 Tax=...   303   2e-81
UniRef50_Q0VRD7 RNA methyltransferase, TrmH family, group 3 n=2 ...   274   1e-72
UniRef50_B5JS83 tRNA (Guanosine-2-O)-methyltransferase n=3 Tax=B...   267   2e-70
UniRef50_Q15Z06 tRNA (Guanosine-2'-O-)-methyltransferase n=2 Tax...   267   2e-70
UniRef50_A1U493 tRNA guanosine-2'-O-methyltransferase n=3 Tax=Ga...   265   9e-70
UniRef50_C5BJC4 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Ga...   262   4e-69
UniRef50_Q1N3Z0 Putative tRNA/rRNA methyltransferase n=1 Tax=Ber...   262   5e-69
UniRef50_A3IM41 RRNA methylase SpoU n=1 Tax=Cyanothece sp. CCY01...   262   8e-69
UniRef50_Q7TV55 tRNA/rRNA methyltransferase (SpoU) n=34 Tax=cell...   261   2e-68
UniRef50_C7R944 tRNA guanosine-2'-O-methyltransferase n=1 Tax=Ka...   257   3e-67
UniRef50_Q0AB97 tRNA guanosine-2'-O-methyltransferase n=2 Tax=Ec...   253   3e-66
UniRef50_A4SEW2 tRNA guanosine-2'-O-methyltransferase n=10 Tax=C...   249   5e-65
UniRef50_C1XS02 rRNA methylase n=2 Tax=Bacteria RepID=C1XS02_9DEIN    249   7e-65
UniRef50_B3QXG6 tRNA guanosine-2'-O-methyltransferase n=1 Tax=Ch...   245   1e-63
UniRef50_A6LPP3 RNA methyltransferase, TrmH family, group 3 n=35...   232   8e-60
UniRef50_A9BJB6 RNA methyltransferase, TrmH family, group 3 n=3 ...   231   2e-59
UniRef50_B0K5F8 RNA methyltransferase, TrmH family, group 3 n=51...   228   9e-59
UniRef50_O67577 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Ba...   227   2e-58
UniRef50_Q1J4P0 23S rRNA Gm2251 methyltransferase n=42 Tax=Lacto...   227   2e-58
UniRef50_C2HJX9 tRNA/rRNA methyltransferase n=3 Tax=Clostridiale...   227   2e-58
UniRef50_P74328 Uncharacterized tRNA/rRNA methyltransferase slr0...   227   2e-58
UniRef50_Q0AUG1 Conserved hypothetical tRNA/rRNA methyltransfera...   225   7e-58
UniRef50_C7PC85 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Chiti...   225   8e-58
UniRef50_Q2JI19 RNA methyltransferase, TrmH family, group 3 n=2 ...   225   9e-58
UniRef50_Q4L3J1 Putative trmH family tRNA/rRNA methyltransferase...   225   1e-57
UniRef50_Q7MH13 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   224   1e-57
UniRef50_A4BEK2 Putative tRNA methyltransferase n=1 Tax=Reinekea...   223   3e-57
UniRef50_Q9JZR3 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   222   6e-57
UniRef50_B8IYB0 tRNA guanosine-2'-O-methyltransferase n=14 Tax=D...   222   6e-57
UniRef50_C8P2I4 23S rRNA (Guanosine-2'-O-)-methyltransferase Rlm...   222   6e-57
UniRef50_C9LMK8 RNA methyltransferase, TrmH family, group 3 n=1 ...   222   7e-57
UniRef50_Q5HIE3 Putative trmH family tRNA/rRNA methyltransferase...   222   8e-57
UniRef50_Q606P1 RNA methyltransferase, TrmH family, group 3 n=1 ...   221   1e-56
UniRef50_B0TC37 RNA methyltransferase, trmh family n=1 Tax=Helio...   221   2e-56
UniRef50_A3DH38 RNA methyltransferase, TrmH family, group 3 n=14...   220   2e-56
UniRef50_B2UR21 RNA methyltransferase, TrmH family, group 3 n=3 ...   220   2e-56
UniRef50_Q5HRM1 Putative trmH family tRNA/rRNA methyltransferase...   220   2e-56
UniRef50_Q1G8Z2 TRNA/rRNA methyltransferase n=109 Tax=Bacilli Re...   220   3e-56
UniRef50_A0L4P9 RNA methyltransferase, TrmH family, group 3 n=1 ...   220   3e-56
UniRef50_B2A4B9 RNA methyltransferase, TrmH family, group 3 n=1 ...   220   3e-56
UniRef50_C5CF29 RNA methyltransferase, TrmH family, group 3 n=7 ...   220   3e-56
UniRef50_B8D0A6 RNA methyltransferase n=11 Tax=Firmicutes RepID=...   219   4e-56
UniRef50_C4V0H0 tRNA/rRNA methyltransferase n=1 Tax=Selenomonas ...   219   6e-56
UniRef50_B2IX93 RNA methyltransferase, TrmH family, group 3 n=1 ...   219   8e-56
UniRef50_Q7MBB6 tRNA/rRNA methyltransferase n=1 Tax=Gloeobacter ...   219   9e-56
UniRef50_Q06753 Putative trmH family tRNA/rRNA methyltransferase...   218   1e-55
UniRef50_C3RMB5 23S rRNA methyltransferase n=5 Tax=Bacteria RepI...   218   1e-55
UniRef50_A4XJ85 RNA methyltransferase, TrmH family, group 3 n=2 ...   218   1e-55
UniRef50_Q1ISZ4 RNA methyltransferase TrmH, group 3 n=2 Tax=Acid...   218   1e-55
UniRef50_B8G1U5 RNA methyltransferase, TrmH family, group 3 n=4 ...   217   2e-55
UniRef50_B9L1B3 tRNA guanosine-2'-O-methyltransferase n=3 Tax=Ba...   217   2e-55
UniRef50_C5NV68 RNA methyltransferase, TrmH family, group 3 n=1 ...   217   2e-55
UniRef50_B8HJN1 RNA methyltransferase, TrmH family, group 3 n=6 ...   217   3e-55
UniRef50_Q82XD1 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   217   3e-55
UniRef50_B3QM30 RNA methyltransferase, TrmH family, group 3 n=12...   217   3e-55
UniRef50_Q88DE7 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   217   3e-55
UniRef50_Q7NYX3 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   217   3e-55
UniRef50_A2U211 SpoU rRNA methylase family protein n=1 Tax=Polar...   217   3e-55
UniRef50_C8WTZ2 RNA methyltransferase, TrmH family, group 3 n=2 ...   216   4e-55
UniRef50_Q1D7V2 RNA methyltransferase, TrmH family, group 3 n=7 ...   216   5e-55
UniRef50_C7H0N3 RNA methyltransferase, TrmH family n=1 Tax=Eubac...   215   7e-55
UniRef50_Q73MR5 RNA methyltransferase, TrmH family, group 3 n=1 ...   215   7e-55
UniRef50_C7REQ2 RNA methyltransferase, TrmH family, group 3 n=4 ...   215   8e-55
UniRef50_A8RFN1 Putative uncharacterized protein n=2 Tax=Erysipe...   215   9e-55
UniRef50_B5EQA2 RNA methyltransferase, TrmH family, group 3 n=3 ...   215   1e-54
UniRef50_Q2LQ81 23S rRNA Gm2251 methyltransferase n=1 Tax=Syntro...   215   1e-54
UniRef50_A8PMQ1 RNA methyltransferase, TrmH family, group 3 n=1 ...   215   1e-54
UniRef50_A6BKK3 Putative uncharacterized protein n=6 Tax=Bacteri...   215   1e-54
UniRef50_A7B5E9 Putative uncharacterized protein n=7 Tax=Bacteri...   214   1e-54
UniRef50_A1HPG2 TRNA/rRNA methyltransferase (SpoU) n=1 Tax=Therm...   214   2e-54
UniRef50_C2BF70 tRNA/rRNA methyltransferase n=1 Tax=Anaerococcus...   214   2e-54
UniRef50_B8I1W5 RNA methyltransferase, TrmH family, group 3 n=5 ...   214   2e-54
UniRef50_C8WR00 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Bacil...   214   2e-54
UniRef50_B0P8C0 Putative uncharacterized protein n=2 Tax=Clostri...   214   2e-54
UniRef50_A1APM1 RNA methyltransferase, TrmH family, group 3 n=8 ...   214   3e-54
UniRef50_D1AP92 RNA methyltransferase, TrmH family, group 3 n=7 ...   213   4e-54
UniRef50_Q83CW6 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   213   4e-54
UniRef50_A7HLT3 RNA methyltransferase, TrmH family, group 3 n=2 ...   212   6e-54
UniRef50_Q1LSR1 RNA methyltransferase, TrmH family, group 3 n=4 ...   211   1e-53
UniRef50_C9RX94 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Geoba...   211   1e-53
UniRef50_B2V596 RNA methyltransferase, TrmH family n=7 Tax=Clost...   211   2e-53
UniRef50_A6CBV4 YacO n=1 Tax=Planctomyces maris DSM 8797 RepID=A...   211   2e-53
UniRef50_A6Q996 tRNA (Guanosine-2'-O-)-methyltransferase n=2 Tax...   210   2e-53
UniRef50_A8STN2 Putative uncharacterized protein n=2 Tax=Clostri...   210   2e-53
UniRef50_C4L0U6 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Ba...   210   2e-53
UniRef50_Q1NS81 RNA methyltransferase TrmH, group 3 n=3 Tax=Delt...   210   3e-53
UniRef50_B7DP24 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Alicy...   210   3e-53
UniRef50_C6CVT7 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Bacil...   210   3e-53
UniRef50_Q14PR4 Putative trna/rrna methyltransferase protein n=1...   210   3e-53
UniRef50_Q724H1 RNA methyltransferase, TrmH family, group 3 n=21...   210   3e-53
UniRef50_Q1JXE5 RNA methyltransferase TrmH, group 3 n=1 Tax=Desu...   210   4e-53
UniRef50_A2C1X9 RNA methyltransferase TrmH, group 3 n=6 Tax=Cyan...   209   4e-53
UniRef50_C1F8Y2 RNA methyltransferase, TrmH family, group 3 n=1 ...   209   4e-53
UniRef50_A1AWI4 RNA methyltransferase, TrmH family, group 3 n=3 ...   209   4e-53
UniRef50_Q0EVP7 RNA methyltransferase, TrmH family, group 3 n=1 ...   209   6e-53
UniRef50_A4GI27 rRNA methyltransferase n=1 Tax=uncultured marine...   209   7e-53
UniRef50_B9ZJH8 RNA methyltransferase, TrmH family, group 3 n=1 ...   209   8e-53
UniRef50_Q31FJ2 RNA methyltransferase TrmH, group 3 n=1 Tax=Thio...   209   9e-53
UniRef50_D2REE3 RNA methyltransferase, TrmH family, group 3 n=1 ...   207   2e-52
UniRef50_C2KW83 Possible RNA methyltransferase n=1 Tax=Oribacter...   207   3e-52
UniRef50_Q6FF50 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   206   4e-52
UniRef50_B0K3L2 tRNA/rRNA methyltransferase (SpoU) n=11 Tax=Ther...   206   5e-52
UniRef50_C0GIN0 RNA methyltransferase, TrmH family, group 3 n=1 ...   206   5e-52
UniRef50_Q7P601 23S rRNA methyltransferase n=10 Tax=Fusobacteriu...   205   6e-52
UniRef50_A5IXH9 tRNA/rRNA methyltransferase n=1 Tax=Mycoplasma a...   205   7e-52
UniRef50_A4J4Z3 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Desul...   205   7e-52
UniRef50_C4G1K9 Putative uncharacterized protein n=1 Tax=Abiotro...   205   8e-52
UniRef50_D2RLA3 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Acida...   205   8e-52
UniRef50_B1X411 tRNA/rRNA methyltransferase (SpoU):RNA methyltra...   205   8e-52
UniRef50_D1U4M7 tRNA guanosine-2'-O-methyltransferase n=1 Tax=De...   205   1e-51
UniRef50_Q9LXE4 rRNA methylase-like protein n=11 Tax=Magnoliophy...   205   1e-51
UniRef50_A3HSD9 SpoU protein (SpoU) n=1 Tax=Algoriphagus sp. PR1...   204   2e-51
UniRef50_B8FEV3 RNA methyltransferase, TrmH family, group 3 n=1 ...   204   2e-51
UniRef50_D0GJ12 RNA methyltransferase, TrmH family, group 3 n=3 ...   204   2e-51
UniRef50_B0TZ81 tRNA/rRNA methyltransferase n=20 Tax=Francisella...   204   2e-51
UniRef50_A8ZSH6 RNA methyltransferase, TrmH family, group 3 n=1 ...   203   3e-51
UniRef50_B2S257 Possible rRNA methylase n=3 Tax=Treponema RepID=...   203   3e-51
UniRef50_A6L4B5 tRNA/rRNA methyltransferase n=16 Tax=Bacteroidet...   203   3e-51
UniRef50_Q87D65 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   203   3e-51
UniRef50_B4WGA5 RNA methyltransferase, TrmH family, group 3, put...   203   4e-51
UniRef50_B1GZS4 23S rRNA (Guanosine-2'-O-)-methyltransferase n=1...   203   4e-51
UniRef50_C7G6D1 RNA methyltransferase, TrmH family n=5 Tax=Clost...   203   4e-51
UniRef50_B5YID5 RNA methyltransferase, TrmH family, group 3 n=1 ...   203   4e-51
UniRef50_B1C951 Putative uncharacterized protein n=1 Tax=Anaerof...   203   5e-51
UniRef50_C6X1H8 rRNA methylase n=4 Tax=Bacteroidetes RepID=C6X1H...   203   5e-51
UniRef50_C4Z380 RNA methyltransferase, TrmH family n=1 Tax=Eubac...   202   5e-51
UniRef50_C0Z9E4 Putative RNA methyltransferase n=1 Tax=Brevibaci...   202   6e-51
UniRef50_Q1IWR8 RNA methyltransferase TrmH, group 3 n=6 Tax=Dein...   202   9e-51
UniRef50_Q3AXD9 RNA methyltransferase TrmH, group 3 n=19 Tax=Bac...   202   9e-51
UniRef50_Q31LC0 RNA methyltransferase TrmH, group 3 n=22 Tax=Bac...   201   1e-50
UniRef50_D1CD69 RNA methyltransferase, TrmH family, group 3 n=1 ...   201   1e-50
UniRef50_C8N9X3 23S rRNA (Guanosine-2'-O-)-methyltransferase Rlm...   201   1e-50
UniRef50_C9KPX8 RNA methyltransferase, TrmH family n=1 Tax=Mitsu...   201   1e-50
UniRef50_C2D9C1 Possible tRNA/rRNA methyltransferase n=1 Tax=Ato...   200   3e-50
UniRef50_D1VT15 RNA methyltransferase, TrmH family, group 3 n=1 ...   200   4e-50
UniRef50_C0WU39 RNA methyltransferase n=3 Tax=Lactobacillus RepI...   199   7e-50
UniRef50_D1R5P1 Putative uncharacterized protein n=1 Tax=Parachl...   199   7e-50
UniRef50_C1TM87 rRNA methylase, putative, group 3 n=1 Tax=Dethio...   199   8e-50
UniRef50_C2FZ75 Possible tRNA/rRNA methyltransferase n=2 Tax=Sph...   199   1e-49
UniRef50_C4L451 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Exigu...   198   1e-49
UniRef50_C7H9L6 RNA methyltransferase, TrmH family, group 3 n=3 ...   198   1e-49
UniRef50_UPI0001C42339 RNA methyltransferase, TrmH family n=1 Ta...   198   1e-49
UniRef50_D2QM84 RNA methyltransferase, TrmH family, group 3 n=2 ...   198   1e-49
UniRef50_B3PM16 SpoU class tRNA/rRNA methyltransferase n=1 Tax=M...   197   2e-49
UniRef50_A5UYW3 RNA methyltransferase, TrmH family, group 3 n=4 ...   197   2e-49
UniRef50_B1I4I6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Candi...   197   2e-49
UniRef50_B1AIB3 RNA methyltransferase, TrmH family, group 3 n=15...   197   2e-49
UniRef50_A5N255 Predicted methyltransferase n=28 Tax=Clostridium...   197   2e-49
UniRef50_A2U3D3 SpoU rRNA methylase n=2 Tax=Flavobacteriaceae Re...   197   3e-49
UniRef50_A8MI79 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Clost...   197   3e-49
UniRef50_Q6AJ92 Related to tRNA/rRNA methyltransferase n=1 Tax=D...   197   3e-49
UniRef50_Q8DNE3 Possible rRNA/tRNA methylase n=69 Tax=Streptococ...   197   3e-49
UniRef50_C4ZGM4 RNA methyltransferase, TrmH family, group 3 n=8 ...   197   4e-49
UniRef50_A9S3U1 Predicted protein (Fragment) n=2 Tax=Physcomitre...   196   4e-49
UniRef50_B4U792 RNA methyltransferase, TrmH family, group 3 n=9 ...   196   4e-49
UniRef50_B6IRN7 RNA methyltransferase, TrmH family, group 3 n=4 ...   196   4e-49
UniRef50_Q0VMF8 RNA methyltransferase, TrmH family, group 3 n=2 ...   196   5e-49
UniRef50_UPI0001C31319 RNA methyltransferase, TrmH family, group...   196   6e-49
UniRef50_Q7VQP0 23S rRNA (guanosine-2'-O-)-methyltransferase rlm...   196   6e-49
UniRef50_C9A4E5 RNA methyltransferase n=3 Tax=Enterococcus casse...   195   6e-49
UniRef50_Q11YB9 tRNA/rRNA methyltransferase, TrmH family n=24 Ta...   195   7e-49
UniRef50_Q2S2J6 RNA methyltransferase, TrmH family, group 3 n=2 ...   195   7e-49
UniRef50_C1ZH70 rRNA methylase, putative, group 3 n=1 Tax=Planct...   195   8e-49
UniRef50_A7HIF7 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Anaer...   195   1e-48
UniRef50_Q8EPH3 rRNA methylase n=1 Tax=Oceanobacillus iheyensis ...   194   1e-48
UniRef50_C0X8M7 RNA methyltransferase n=36 Tax=Enterococcus RepI...   194   1e-48
UniRef50_B1GYT1 23S rRNA methyltransferase n=1 Tax=uncultured Te...   194   2e-48
UniRef50_B3ETE6 Putative uncharacterized protein n=1 Tax=Candida...   194   2e-48
UniRef50_B8D292 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Halot...   194   2e-48
UniRef50_Q7TU91 tRNA/rRNA methyltransferase n=3 Tax=Prochlorococ...   194   3e-48
UniRef50_D1NAJ1 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Victi...   194   3e-48
UniRef50_B5YF75 RNA methyltransferase, TrmH family, group 3 n=2 ...   194   3e-48
UniRef50_D1Y8A8 RNA methyltransferase, TrmH family, group 3 (Fra...   194   3e-48
UniRef50_A5F9W1 tRNA/rRNA methyltransferase (SpoU) n=16 Tax=Bact...   193   3e-48
UniRef50_B5JMU7 RNA methyltransferase, TrmH family n=1 Tax=Verru...   193   4e-48
UniRef50_D1J7J9 tRNA/rRNA methyltransferase n=2 Tax=Mycoplasma R...   193   5e-48
UniRef50_A9KHD7 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Clost...   192   6e-48
UniRef50_B5CKU5 Putative uncharacterized protein n=1 Tax=Ruminoc...   192   6e-48
UniRef50_A0M5B1 TrmH family tRNA/rRNA methyltransferase n=16 Tax...   192   8e-48
UniRef50_Q3A6R3 rRNA methyltranferase n=2 Tax=Desulfuromonadales...   192   8e-48
UniRef50_UPI000196B15F hypothetical protein CATMIT_01248 n=1 Tax...   192   9e-48
UniRef50_A1WUS8 RNA methyltransferase, TrmH family, group 3 n=8 ...   192   1e-47
UniRef50_C8NEH0 TrmH family RNA methyltransferase n=2 Tax=Granul...   192   1e-47
UniRef50_B1I0T3 RNA methyltransferase, TrmH family, group 3 n=2 ...   192   1e-47
UniRef50_B8DUY4 tRNA/rRNA methyltransferase n=5 Tax=Bifidobacter...   192   1e-47
UniRef50_D0MG21 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Rhodo...   191   1e-47
UniRef50_C9M6N6 RNA methyltransferase, TrmH family, group 3 n=1 ...   191   2e-47
UniRef50_D1AU26 RNA methyltransferase n=1 Tax=Anaplasma centrale...   191   2e-47
UniRef50_A5EVE3 RNA methyltransferase, TrmH family, group 3 n=1 ...   190   2e-47
UniRef50_P94538 Uncharacterized tRNA/rRNA methyltransferase ysgA...   190   2e-47
UniRef50_Q2RFM6 RNA methyltransferase TrmH, group 3 n=2 Tax=Clos...   190   2e-47
UniRef50_Q2S465 RRNA methylase n=1 Tax=Salinibacter ruber DSM 13...   190   3e-47
UniRef50_C9RBD1 RNA methyltransferase, TrmH family, group 3 n=1 ...   190   3e-47
UniRef50_C8W818 RNA methyltransferase, TrmH family, group 3 n=7 ...   190   3e-47
UniRef50_A4XKC2 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Clost...   190   3e-47
UniRef50_C7MMG3 rRNA methylase, putative, group 3 n=1 Tax=Crypto...   190   3e-47
UniRef50_B2GD96 rRNA methylase n=26 Tax=Bacilli RepID=B2GD96_LACF3    190   3e-47
UniRef50_A7VXH5 Putative uncharacterized protein n=1 Tax=Clostri...   190   4e-47
UniRef50_C0W229 tRNA/rRNA methyltransferase n=2 Tax=Actinomyces ...   190   4e-47
UniRef50_C7PMX4 RNA methyltransferase, TrmH family, group 3 n=1 ...   189   5e-47
UniRef50_Q6MA83 Putative rRNA methylase n=2 Tax=Chlamydiae/Verru...   189   6e-47
UniRef50_D1PXH3 SpoU rRNA methylase n=1 Tax=Prevotella bergensis...   189   6e-47
UniRef50_C5WEU6 23S rRNA methyltransferase n=2 Tax=Firmicutes Re...   189   7e-47
UniRef50_D0JB44 tRNA/rRNA methyltransferase n=2 Tax=Blattabacter...   189   7e-47
UniRef50_A0LPE7 RNA methyltransferase, TrmH family, group 3 n=1 ...   189   7e-47
UniRef50_A8S2F6 Putative uncharacterized protein n=8 Tax=Clostri...   189   9e-47
UniRef50_Q2GL62 RNA methyltransferase, TrmH family, group 3 n=5 ...   189   9e-47
UniRef50_B1ZVF9 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Opitu...   189   1e-46
UniRef50_Q1IND6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Candi...   188   1e-46
UniRef50_C4V3B4 TrmH family rRNA methyltransferase n=2 Tax=Selen...   188   1e-46
UniRef50_B9KYY7 RNA methyltransferase, TrmH family, group 3 n=4 ...   188   1e-46
UniRef50_B0PD55 Putative uncharacterized protein n=1 Tax=Anaerot...   188   1e-46
UniRef50_B9E768 rRNA methyltransferase homolog n=1 Tax=Macrococc...   188   1e-46
UniRef50_D0LZ96 RNA methyltransferase, TrmH family, group 3 n=1 ...   188   1e-46
UniRef50_A4E9D9 Putative uncharacterized protein n=1 Tax=Collins...   188   1e-46
UniRef50_B0MRI6 Putative uncharacterized protein n=1 Tax=Eubacte...   188   2e-46
UniRef50_B7C827 Putative uncharacterized protein n=1 Tax=Eubacte...   187   2e-46
UniRef50_Q112U6 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Oscil...   187   2e-46
UniRef50_Q6MNP1 Putative RNA methylase n=1 Tax=Bdellovibrio bact...   187   2e-46
UniRef50_B3RWG3 Putative uncharacterized protein n=1 Tax=Trichop...   187   2e-46
UniRef50_B7GPD2 RNA methyltransferase, TrmH family, group 3 n=4 ...   187   3e-46
UniRef50_O51468 Uncharacterized tRNA/rRNA methyltransferase BB_0...   187   3e-46
UniRef50_B0MYM4 Putative uncharacterized protein n=1 Tax=Alistip...   187   3e-46
UniRef50_Q4A651 Putative tRNA/rRNA methyltransferase n=1 Tax=Myc...   187   3e-46
UniRef50_A8R7Q7 Putative uncharacterized protein n=1 Tax=Eubacte...   187   3e-46
UniRef50_Q038C4 rRNA methylase n=8 Tax=Lactobacillus RepID=Q038C...   186   4e-46
UniRef50_Q7MTU3 RNA methyltransferase, TrmH family n=5 Tax=Bacte...   186   4e-46
UniRef50_Q03G93 rRNA methylase n=1 Tax=Pediococcus pentosaceus A...   186   5e-46
UniRef50_Q1G9C5 TRNA/rRNA methyltransferase n=28 Tax=Lactobacill...   186   6e-46
UniRef50_B9Y9V6 Putative uncharacterized protein n=1 Tax=Holdema...   186   6e-46
UniRef50_C9XLS4 Putative RNA methylase n=9 Tax=Clostridium RepID...   185   8e-46
UniRef50_A6P2D0 Putative uncharacterized protein n=1 Tax=Bactero...   185   9e-46
UniRef50_C0BGA8 RNA methyltransferase, TrmH family, group 3 n=1 ...   185   9e-46
UniRef50_C0W457 tRNA/rRNA methyltransferase n=2 Tax=Actinomyceta...   185   1e-45
UniRef50_C6VPS4 rRNA methylase n=8 Tax=Lactobacillales RepID=C6V...   185   1e-45
UniRef50_D2RCJ3 RNA methyltransferase, TrmH family, group 3 n=14...   185   1e-45
UniRef50_O30272 Uncharacterized tRNA/rRNA methyltransferase AF_2...   184   2e-45
UniRef50_C2KTT3 TrmH family tRNA/rRNA methyltransferase n=2 Tax=...   184   2e-45
UniRef50_C1E8J5 Predicted protein (Fragment) n=3 Tax=Mamiellales...   184   2e-45
UniRef50_D2EID2 TrmH family RNA methyltransferase n=1 Tax=Pedioc...   184   2e-45
UniRef50_UPI0001BC4585 23S rRNA methyltransferase n=1 Tax=Fusoba...   184   3e-45
UniRef50_B5YIM1 RNA methyltransferase, TrmH family n=1 Tax=Therm...   184   3e-45
UniRef50_A9WLY5 23S rRNA methyltransferase TrmH, group 3 n=11 Ta...   184   3e-45
UniRef50_A5US41 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Chlor...   183   4e-45
UniRef50_A8DJH5 TsnR n=1 Tax=Candidatus Chloracidobacterium ther...   183   4e-45
UniRef50_Q7MW92 RNA methyltransferase, TrmH family n=2 Tax=Porph...   183   4e-45
UniRef50_B6YR56 23S rRNA (Guanosine-2'-O-)-methyltransferase n=1...   183   4e-45
UniRef50_UPI00016C0619 tRNA/rRNA methyltransferase (SpoU) n=1 Ta...   183   5e-45
UniRef50_B2KBE6 RNA methyltransferase, TrmH family, group 3 n=1 ...   182   6e-45
UniRef50_C5SHP3 RNA methyltransferase, TrmH family, group 3 n=3 ...   182   6e-45

Sequences not found previously or not previously below threshold:

>UniRef50_P0AGJ3 tRNA guanosine-2'-O-methyltransferase n=231 Tax=Bacteria
           RepID=TRMH_ECO57
          Length = 229

 Score =  303 bits (778), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 229/229 (100%), Positives = 229/229 (100%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM
Sbjct: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
           ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ
Sbjct: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE
Sbjct: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQAAG 229
           AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQAAG
Sbjct: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQAAG 229


>UniRef50_Q0VRD7 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Alcanivorax
           RepID=Q0VRD7_ALCBS
          Length = 230

 Score =  274 bits (703), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 110/228 (48%), Positives = 154/228 (67%), Gaps = 2/228 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M P RY RIC+ L RRQPDLTV M+ VHKPHN++AI+RT DAVG+ +VHAV P +R R  
Sbjct: 1   MTPERYRRICDTLDRRQPDLTVIMDGVHKPHNIAAIVRTCDAVGILDVHAVLPKNRARMA 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
           A  A GS  WVQV       D +  L+GQG+Q+LA HLSD+A+++R++DYTRPT +L+G 
Sbjct: 61  AGTAMGSQRWVQVHKRDESTDVIRELQGQGVQVLAAHLSDDAIEYRQVDYTRPTALLLGT 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G++ E  +  DQ++ IPM+GMV+S NVSVA+A+IL EA  QR+  G Y  +   +  
Sbjct: 121 EKFGVSDEVASAVDQNVTIPMMGMVESFNVSVAAAIILSEACEQRRAKGFY--DQPRVAA 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQAA 228
           A    LLF  GY  +A++    G+PYP ++++G+++  A   A +Q  
Sbjct: 179 ARYHELLFRWGYARIARLCDAHGVPYPELDEEGQVKDSAALTALLQKT 226


>UniRef50_B5JS83 tRNA (Guanosine-2-O)-methyltransferase n=3 Tax=Bacteria
           RepID=B5JS83_9GAMM
          Length = 225

 Score =  267 bits (684), Expect = 2e-70,   Method: Composition-based stats.
 Identities = 114/216 (52%), Positives = 148/216 (68%), Gaps = 2/216 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M+P R+ R  + L RRQ  LTV ME VHKPHN SAI+R+ +AVGVH  HAV+P   +   
Sbjct: 1   MSPERHQRFIDTLKRRQTSLTVVMENVHKPHNFSAIVRSCEAVGVHRAHAVYPEGGIGNN 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
           A    G++ WVQV THR I      LK QG Q+L  HL + AVDFRE+DYT+PT ++MG 
Sbjct: 61  AGTTVGAHKWVQVDTHRNIQTPFQQLKAQGFQLLTAHLDETAVDFREVDYTQPTAVVMGS 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E  GI++EA  LAD  I+IPM+G+ +SLNVSVA+ALIL+EAQRQRQ AGMY  E   L E
Sbjct: 121 ELHGISEEAAQLADHSIVIPMLGLTESLNVSVATALILFEAQRQRQLAGMY--EQPELDE 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIE 216
           A ++ L+FE  YP LA+  + +G PYP ++ +G + 
Sbjct: 179 ATRKTLMFEWAYPDLARRYQSRGEPYPELDDEGYLV 214


>UniRef50_Q15Z06 tRNA (Guanosine-2'-O-)-methyltransferase n=2 Tax=Pseudoalteromonas
           atlantica T6c RepID=Q15Z06_PSEA6
          Length = 256

 Score =  267 bits (683), Expect = 2e-70,   Method: Composition-based stats.
 Identities = 133/229 (58%), Positives = 175/229 (76%), Gaps = 3/229 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M+  RY RI ++L+ RQP LTVC+EQVHKPHNVSA++R+ DAVG++ +H VW     +  
Sbjct: 7   MSVERYQRIRKLLSTRQPSLTVCLEQVHKPHNVSAVLRSCDAVGINRIHGVWDQK-TKIR 65

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A GS  WV+ + H +IGDAV+ LK Q MQ+L THLSD++VDFR+IDYT+PT I++GQ
Sbjct: 66  KGTAMGSEHWVKTEMHTSIGDAVSVLKQQNMQVLVTHLSDDSVDFRDIDYTQPTAIILGQ 125

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G T+EA+A+AD++I+IPM+GMVQSLNVSVA+A++LYEAQRQR+ AGMY   +  L E
Sbjct: 126 EKHGATEEAIAVADKNIVIPMVGMVQSLNVSVAAAVVLYEAQRQREVAGMY--NSLQLSE 183

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQAAG 229
            E QR+LFEGG+PVL+ V + KGL YPH+++ G I ADA WW  MQ   
Sbjct: 184 EECQRVLFEGGFPVLSNVCRNKGLDYPHIDEGGNIVADASWWQKMQTTA 232


>UniRef50_A1U493 tRNA guanosine-2'-O-methyltransferase n=3 Tax=Gammaproteobacteria
           RepID=A1U493_MARAV
          Length = 244

 Score =  265 bits (678), Expect = 9e-70,   Method: Composition-based stats.
 Identities = 105/227 (46%), Positives = 139/227 (61%), Gaps = 3/227 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M P R ARI ++L  RQPDL V  +QVHKP N+SAIIR+ DA G+  +H VWP    R  
Sbjct: 1   MTPERLARIKQVLNTRQPDLRVLTDQVHKPRNLSAIIRSCDAFGLANMHVVWPKEGFRAF 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A GS  WV   TH T+ +AV  LK QG ++ A  LSD AVDFRE+DYT P  I+MG 
Sbjct: 61  RKTAGGSFHWVTTHTHPTMDNAVTELKAQGHKLYAAQLSDRAVDFREVDYTVPCTIIMGN 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E  G+       AD+ I+IPM+GMV+SLNVS A ++IL EAQRQR+ AGM+  +   +P+
Sbjct: 121 EVDGVNPVTAEQADEHIVIPMMGMVESLNVSSACSIILSEAQRQRKLAGMF--DQRRMPD 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQ-GEIEADADWWATMQ 226
            E  RLLF    P + +    + LPYP ++ + GE+     W   ++
Sbjct: 179 DEYNRLLFCWCQPTVKRYCDDRNLPYPPIDHETGELIDGVGWMQEVR 225


>UniRef50_C5BJC4 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Gammaproteobacteria
           RepID=C5BJC4_TERTT
          Length = 228

 Score =  262 bits (672), Expect = 4e-69,   Method: Composition-based stats.
 Identities = 98/227 (43%), Positives = 142/227 (62%), Gaps = 2/227 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M P R+ RI  +L +RQPDLTV  ++VHK  N+SAI RT DAVG+  +H V P    +T 
Sbjct: 1   MTPERFQRITSVLNKRQPDLTVITDEVHKGRNLSAITRTCDAVGIDTIHCVMPEDGYQTY 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              +A +  WV V+ H +I   V  LK +G Q++A +L DN +D+R +DYT+PT +++G 
Sbjct: 61  NGTSASAEKWVAVQHHSSISAPVNDLKREGFQLVAANLGDNTLDYRNVDYTKPTALVLGA 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E  G++ EA A  D ++ +PM+GMV+S NVSVA+A+IL EAQ QRQ AG+Y  +   L  
Sbjct: 121 EVKGVSPEAAAAVDYNVTVPMVGMVESFNVSVAAAIILMEAQHQRQQAGLY--DQPRLTA 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQA 227
              +   F   +PVLAK     G+ YP V + GE++  + W++  QA
Sbjct: 179 DVYRARFFHWAHPVLAKWCDDNGVEYPPVREDGEVKNLSAWYSAEQA 225


>UniRef50_Q1N3Z0 Putative tRNA/rRNA methyltransferase n=1 Tax=Bermanella marisrubri
           RepID=Q1N3Z0_9GAMM
          Length = 229

 Score =  262 bits (672), Expect = 5e-69,   Method: Composition-based stats.
 Identities = 104/224 (46%), Positives = 138/224 (61%), Gaps = 2/224 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M P R  R+ ++L +RQPDLT+  + V KPHN+SAIIR+ DA  V+E++ VWP    +T 
Sbjct: 1   MTPERVQRMHDILRKRQPDLTLITDAVFKPHNLSAIIRSCDAFAVNELNVVWPYDDYQTF 60

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A GS  +V VKTH+ +  A+   K QG QI+A H  D AV   +IDYT+PT I+MG 
Sbjct: 61  RGRAMGSQQYVNVKTHKDVSQAIQGFKQQGYQIVAAHFCDQAVPHYDIDYTKPTAIVMGA 120

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G++ +A+ L D  II+PM GMVQSLNVSVA+ALIL EA  QR+N GM     + L  
Sbjct: 121 EKNGVSAKAMDLVDHSIIVPMEGMVQSLNVSVAAALILSEAMHQRKNKGML--GENQLDS 178

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWAT 224
              Q   FE  YP LAK  K+ G+ YP + + G+    A +   
Sbjct: 179 ETYQIQFFEWCYPDLAKRCKKLGMAYPKLKENGDFVEPAAFSKE 222


>UniRef50_A3IM41 RRNA methylase SpoU n=1 Tax=Cyanothece sp. CCY0110
           RepID=A3IM41_9CHRO
          Length = 220

 Score =  262 bits (670), Expect = 8e-69,   Method: Composition-based stats.
 Identities = 106/216 (49%), Positives = 143/216 (66%), Gaps = 2/216 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           + P RY RI ++L +RQPDLT+  E VHKPHN+SAIIRT DAVG+ +VH +       T 
Sbjct: 3   LLPRRYHRIRQVLEKRQPDLTILTEDVHKPHNLSAIIRTCDAVGILDVHCINTTDEFPTF 62

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
           +  + GS+ WV + +H  I   + HLK Q   I A H +D ++D+REIDYT+PT IL+G 
Sbjct: 63  SQVSQGSDKWVFLHSHPNIKTGINHLKRQNFNIYAAHFTDQSLDYREIDYTQPTAILLGA 122

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G+++EA  L D  II+PM+GMVQSLNVSVA+A+IL+EAQRQR    MY  + S L  
Sbjct: 123 EKWGVSEEAANLVDGHIIVPMLGMVQSLNVSVAAAVILFEAQRQRLAQKMY--DTSRLDL 180

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIE 216
               ++LFE  YP LA + ++KG  YP + + G I 
Sbjct: 181 DRYHKILFEWSYPALATIYQKKGENYPSLGKNGVIL 216


>UniRef50_Q7TV55 tRNA/rRNA methyltransferase (SpoU) n=34 Tax=cellular organisms
           RepID=Q7TV55_PROMM
          Length = 245

 Score =  261 bits (667), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 100/218 (45%), Positives = 137/218 (62%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           + P R+ R+  +L  R  DLTV +E V KPHN+SAI+R+ DAVGV E HAV    R+ T 
Sbjct: 19  LLPRRFDRLKAVLDCRMADLTVLLEHVEKPHNLSAILRSCDAVGVLEAHAVNYSGRLPTF 78

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
            S A GS  W+ +K H +I  AV  +K  G ++  THL  NA D+R+ D+  PT  ++G 
Sbjct: 79  NSTAQGSQKWIPLKEHSSIEVAVKAIKDSGFRLYGTHLGGNARDYRDCDFCEPTAFVLGA 138

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G+++ A  L D+ I IPM GMVQSLNVSVA+A +L+EA RQR+ AG+  +    L  
Sbjct: 139 EKWGLSKLATPLMDEGIFIPMSGMVQSLNVSVAAATLLFEALRQRRLAGIAPQAGEGLEP 198

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEAD 218
           A  Q+ LFE  YP +A   +++G  YP +N QGEI+  
Sbjct: 199 ALYQQRLFEWAYPEVAAWCQQEGKSYPALNDQGEIQGS 236


>UniRef50_C7R944 tRNA guanosine-2'-O-methyltransferase n=1 Tax=Kangiella koreensis
           DSM 16069 RepID=C7R944_KANKD
          Length = 231

 Score =  257 bits (657), Expect = 3e-67,   Method: Composition-based stats.
 Identities = 110/220 (50%), Positives = 151/220 (68%), Gaps = 3/220 (1%)

Query: 2   NPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA 61
           +P R  +I  +L+ RQPDLTV M+QVHKPHN++AI+RTADAVG+  VHAV+P     T  
Sbjct: 5   SPARLQKILTLLSNRQPDLTVFMDQVHKPHNLAAIVRTADAVGIGHVHAVFPEDVKFTGH 64

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
             ++GS  WV    H  +   +A +K +GMQ+LA H SD AVDFR IDYT+PTC+L+G E
Sbjct: 65  HTSSGSKRWVTTHKHSNLKSGIAEMKAKGMQVLAAHFSDTAVDFRTIDYTQPTCLLVGSE 124

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEA 181
             G++ EA  +ADQ +IIPM+GMVQSLNVSVA+ALILYEAQRQR +A MY      +P+A
Sbjct: 125 LVGVSDEAAEIADQHVIIPMVGMVQSLNVSVATALILYEAQRQRSDAEMY--GECKIPQA 182

Query: 182 EQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADW 221
           E   + F+  +P + +   +  + YP +++ G+I  D +W
Sbjct: 183 EVDEICFKALHPTITRFCDKHKIRYPKMDEFGDI-DDPEW 221


>UniRef50_Q0AB97 tRNA guanosine-2'-O-methyltransferase n=2
           Tax=Ectothiorhodospiraceae RepID=Q0AB97_ALHEH
          Length = 220

 Score =  253 bits (648), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 106/217 (48%), Positives = 148/217 (68%), Gaps = 4/217 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M   R  R+ + L RRQPDL V ++QVHKPHN+SAI+RT DAVGV   HAV       T+
Sbjct: 1   MTARRLHRMRQTLERRQPDLQVLLDQVHKPHNLSAILRTCDAVGVPRAHAVSRHQD-FTV 59

Query: 61  ASA-AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
             A ++G+  WV V+TH  +  AV  ++GQGM++ A HLS+ AVD+R++DYT+P C+L+G
Sbjct: 60  HRAASSGTGQWVAVETHADLPAAVRAVQGQGMKVYAAHLSEQAVDYRQVDYTKPCCLLLG 119

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            EK G+++E  ALAD  +IIPM G+  SLNVSVA+A+IL+EAQRQR  AG Y  E   + 
Sbjct: 120 AEKEGVSEEGAALADGHVIIPMFGLGASLNVSVAAAVILFEAQRQRLAAGQY--ETPRMA 177

Query: 180 EAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIE 216
           EAE  R L E  +P +A+  +++G PYP +++ G + 
Sbjct: 178 EAEITRTLVEWLHPRIAERCRKEGRPYPALDEDGGVI 214


>UniRef50_A4SEW2 tRNA guanosine-2'-O-methyltransferase n=10 Tax=Chlorobiaceae
           RepID=A4SEW2_PROVI
          Length = 232

 Score =  249 bits (637), Expect = 5e-65,   Method: Composition-based stats.
 Identities = 103/216 (47%), Positives = 143/216 (66%), Gaps = 2/216 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           + P R+ RI +MLA RQPDLTV M+ V+KPHN+SAIIR+ DAVG+H+++AV     + T 
Sbjct: 2   IAPERFLRIKKMLASRQPDLTVVMDNVNKPHNLSAIIRSCDAVGIHDLYAVSSKKSIHTT 61

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
            +AAAG+  W  +   + IG     L  +GMQ+LA   ++ + DFR ID+T PT I++G 
Sbjct: 62  QNAAAGAGRWTNLHLRKDIGTLCRKLGMEGMQVLAATNTEESRDFRTIDFTLPTAIVLGA 121

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E  G++ EA+  AD  I IPM GMV+SLNVSVA+ALIL+EA+RQR   GMY      L E
Sbjct: 122 EWEGVSAEAIQAADMAITIPMYGMVESLNVSVAAALILFEAERQRSLKGMY--RTRRLEE 179

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIE 216
           +  ++LLFE  YP L++  + KG  YP +++ G I 
Sbjct: 180 SLYRKLLFELSYPRLSRQLREKGGAYPELDEDGGIV 215


>UniRef50_C1XS02 rRNA methylase n=2 Tax=Bacteria RepID=C1XS02_9DEIN
          Length = 228

 Score =  249 bits (636), Expect = 7e-65,   Method: Composition-based stats.
 Identities = 112/224 (50%), Positives = 149/224 (66%), Gaps = 10/224 (4%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAV--------W 52
           M P R+ +I ++LARRQPDLTV ME+VHK HN SA++R+ DAVGV E H +         
Sbjct: 1   MTPERWQKIQQVLARRQPDLTVLMERVHKWHNFSAVLRSCDAVGVLEAHLIPAAHGIPTE 60

Query: 53  PGSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR 112
             +  R  A+ +  +  WV ++T+     A A L+ +G  I A H S  A+D+RE+DYTR
Sbjct: 61  DQNPSRHTAATSGSAAKWVGLRTYPDTPSAFADLRSRGFVIYAAHFSHKAIDYREVDYTR 120

Query: 113 PTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYL 172
           PTCIL+G EK G+T+EA  LAD  I+IPM+GMVQSLNVSVA+A+IL+EAQRQR  AGMY 
Sbjct: 121 PTCILLGTEKWGVTEEAATLADGHIVIPMMGMVQSLNVSVAAAVILFEAQRQRIQAGMY- 179

Query: 173 RENSMLPEAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIE 216
            +   L  A  QRLLFE  YP  A+  +++G  YP ++ +GEI 
Sbjct: 180 -DRPRLEPALHQRLLFEWAYPDWAERCRKEGRDYPALSPEGEIL 222


>UniRef50_B3QXG6 tRNA guanosine-2'-O-methyltransferase n=1 Tax=Chloroherpeton
           thalassium ATCC 35110 RepID=B3QXG6_CHLT3
          Length = 219

 Score =  245 bits (626), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 102/216 (47%), Positives = 144/216 (66%), Gaps = 2/216 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           ++  R+ +I  +L +RQPDLTV ME V+K HN++AIIRT DAVG+ +VHAV     +RT 
Sbjct: 4   VSSDRFQQIKRLLDKRQPDLTVVMENVNKAHNLAAIIRTCDAVGIPKVHAVALRPEIRTK 63

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
            ++A+G+N WV V+ H +  D  + L+  G QI   H S  A DFR +D+T+PT +++G 
Sbjct: 64  QNSASGANRWVDVQIHNSTEDVFSTLRQGGFQIFVAHFSPQATDFRAVDFTKPTALVVGA 123

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E  GI++ A++LAD  + +PM+GMV+SLNVSVA+A++L+EAQRQR   G Y  +   L E
Sbjct: 124 EWEGISETAISLADGSLYVPMVGMVESLNVSVATAIMLFEAQRQRTEKGFY--DKPRLDE 181

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIE 216
           A  QRLLFE  YP +A   K+K    P +N  GEI 
Sbjct: 182 ATYQRLLFELTYPQIATAYKQKDKALPKMNMDGEIL 217


>UniRef50_A6LPP3 RNA methyltransferase, TrmH family, group 3 n=35 Tax=Firmicutes
           RepID=A6LPP3_CLOB8
          Length = 300

 Score =  232 bits (592), Expect = 8e-60,   Method: Composition-based stats.
 Identities = 46/173 (26%), Positives = 88/173 (50%), Gaps = 7/173 (4%)

Query: 1   MNPTRYARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P +Y+ + ++L     R +    V +++V  PHN+ +I+RTA+  GVH +      S 
Sbjct: 129 VTPYKYSEVSDILDLAEKRGEAPFIVILDEVEDPHNLGSIVRTAELFGVHGIILPKRRSA 188

Query: 57  MR--TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T+  ++ G+   V++     +   +  LK +G+ I    +      + ++D+  P 
Sbjct: 189 SVSTTVYKSSVGAIEHVKIAKVTNLNSTIEELKEKGIWIYGADIRAEEYSY-QVDFGGPC 247

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
            +++G E  GI++  +   D+ I IPM+G + SLN SVA  +I+YE  + R  
Sbjct: 248 AVIIGNEGRGISKLTVEKCDKLIKIPMVGKINSLNASVAGGIIMYEVLKGRLK 300


>UniRef50_A9BJB6 RNA methyltransferase, TrmH family, group 3 n=3 Tax=Thermotogaceae
           RepID=A9BJB6_PETMO
          Length = 240

 Score =  231 bits (590), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 43/166 (25%), Positives = 82/166 (49%), Gaps = 5/166 (3%)

Query: 2   NPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRT 59
           N  +Y  + +++  ++    V ++Q+  PHN  AI+RT+ A GV  +      +      
Sbjct: 74  NDFKYENL-DIIEGKEKLFLVILDQIQDPHNFGAIVRTSVAAGVDAIIIPKDNAVEVTPV 132

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
           +   ++G    + +     + + +  LK + + +    +      + EID+    C++ G
Sbjct: 133 VIKVSSGQIFKIPIIKVTNLSNTIETLKKENVWVYGADVEG--KPYYEIDWQGKICLVFG 190

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            E  GI +      D+ + IPM   V+SLNVSV+S +IL+EA++QR
Sbjct: 191 NEGNGIRKNVKNHCDELVSIPMFNNVESLNVSVSSGIILFEAKKQR 236


>UniRef50_B0K5F8 RNA methyltransferase, TrmH family, group 3 n=51 Tax=Firmicutes
           RepID=B0K5F8_THEPX
          Length = 247

 Score =  228 bits (583), Expect = 9e-59,   Method: Composition-based stats.
 Identities = 44/169 (26%), Positives = 91/169 (53%), Gaps = 7/169 (4%)

Query: 4   TRYARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--M 57
            +Y  + ++L     +++    + ++++  PHN+ AIIR+A+A GVH +      +    
Sbjct: 77  YKYFEVDDLLEYAEQKKEKPFLLILDEITDPHNLGAIIRSAEAFGVHGIIIPKRRAVGVN 136

Query: 58  RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
            T+   +AG+   +++     I + +  LK +G+ I+ T ++     F E++Y  P   +
Sbjct: 137 ATVVKTSAGAVEHMRIAKVSNINNTIRDLKERGLWIVGTDVNAE-KSFEELNYDFPVAFV 195

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           +G E  G+++  L   D  + IPM G + SLN SVA+++++Y+   +R+
Sbjct: 196 IGNEGKGVSKLVLQNCDFVVKIPMKGKINSLNASVAASILIYQVVSKRK 244


>UniRef50_O67577 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Bacteria
           RepID=TRMH_AQUAE
          Length = 211

 Score =  227 bits (581), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 85/204 (41%), Positives = 122/204 (59%), Gaps = 7/204 (3%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           +   R  R+ E+L +RQ DL V  + V   HN SAI+RT DAVGV  ++  +  +  +  
Sbjct: 7   VLEKRLKRLREVLEKRQKDLIVFADNVKNEHNFSAIVRTCDAVGV--LYLYYYHAEGKKA 64

Query: 61  A---SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
                   GS+ WV ++        +   K +G QI+AT LS  +V+FRE+DYT+PT ++
Sbjct: 65  KINEGITQGSHKWVFIEKVDNPVQKLLEFKNRGFQIVATWLSKESVNFREVDYTKPTVLV 124

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSM 177
           +G E  G++ E + +AD+ I+IPM GM QSLNVSVA+ +ILYEAQRQR+  GMY R    
Sbjct: 125 VGNELQGVSPEIVEIADKKIVIPMYGMAQSLNVSVATGIILYEAQRQREEKGMYSR--PS 182

Query: 178 LPEAEQQRLLFEGGYPVLAKVAKR 201
           L E E Q++L +  Y  + K  KR
Sbjct: 183 LSEEEIQKILKKWAYEDVIKERKR 206


>UniRef50_Q1J4P0 23S rRNA Gm2251 methyltransferase n=42 Tax=Lactobacillales
           RepID=Q1J4P0_STRPF
          Length = 257

 Score =  227 bits (580), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 46/165 (27%), Positives = 77/165 (46%), Gaps = 4/165 (2%)

Query: 4   TRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMA 61
           T    I E+  +    L + ++ +  PHN+ +I+RTADA  V  V      S      ++
Sbjct: 95  TDVDEILEIAEQEANPLILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVS 154

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
             + G+   + +     +   +  LK +G  I  T ++    D    +      +++G E
Sbjct: 155 KTSTGAVEHIPIARVTNLSQTLDKLKARGFWIFGTDMNGTPSDCWNTN--GKLALVIGNE 212

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
             GI+       D+ I IPM G VQSLN SVA+A+++YE  R R+
Sbjct: 213 GKGISTNIKKQVDEMITIPMNGHVQSLNASVAAAILMYEVFRNRR 257


>UniRef50_C2HJX9 tRNA/rRNA methyltransferase n=3 Tax=Clostridiales Family XI.
           Incertae Sedis RepID=C2HJX9_PEPMA
          Length = 244

 Score =  227 bits (580), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 44/171 (25%), Positives = 80/171 (46%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS- 55
           M    Y+ + EM+       +    + ++++  PHN+ +IIRTA+  G H V      + 
Sbjct: 72  MPSFGYSSVDEMIIYAKKINEDPFLIILDEITDPHNLGSIIRTAEVAGCHGVIIPKHRAC 131

Query: 56  -RMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T    +AG+   +++     I   + +LK   + I      + +    + +   P 
Sbjct: 132 EVNATAIKTSAGAVFNIKIARVTNITTTINYLKEHNIWIYGA-CGEASQTHTQANLKGPI 190

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            +++G E  GI++      DQ I IPM G  +SLN S A+++++YE  RQR
Sbjct: 191 GLVIGNEGKGISRLVRENCDQLIKIPMYGKTESLNASNAASILIYEIIRQR 241


>UniRef50_P74328 Uncharacterized tRNA/rRNA methyltransferase slr0955 n=1
           Tax=Synechocystis sp. PCC 6803 RepID=Y955_SYNY3
          Length = 384

 Score =  227 bits (580), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 47/171 (27%), Positives = 77/171 (45%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P  Y  + +++ + +      + + ++ +  PHN+ AIIRTA+A G   +        
Sbjct: 195 VAPYHYWELGDLIDKAKSQSTAPVLIIIDSITDPHNLGAIIRTAEAFGAQGMVLPQRRVA 254

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T+   AAG+     V     +  A+  LK  G  I  T ++       + D   P 
Sbjct: 255 GITSTVMKVAAGALEHFPVARVVNLSRALETLKESGFWIYGT-VAGKQTALHQADLREPM 313

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            +++G E  G++       D  I IP+ G   SLN SVA+A+ LYE  RQR
Sbjct: 314 GLVIGSEGEGLSLLTQKHCDHLITIPLAGKTPSLNASVAAAISLYEIFRQR 364


>UniRef50_Q0AUG1 Conserved hypothetical tRNA/rRNA methyltransferase yacO n=1
           Tax=Syntrophomonas wolfei subsp. wolfei str. Goettingen
           RepID=Q0AUG1_SYNWW
          Length = 248

 Score =  225 bits (576), Expect = 7e-58,   Method: Composition-based stats.
 Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 8/171 (4%)

Query: 4   TRYARICEMLAR-----RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR-- 56
             YA + ++L +      +P   + ++ +  P N+ AIIRTA+  GV  +      S   
Sbjct: 75  YPYADLGQVLEKLQAQKEKPPFLLLLDGIEDPQNLGAIIRTAECAGVDGIIIPSHKSAEV 134

Query: 57  MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
             T++  +AG+   + +     + + + +LK +G  +L          +       PT +
Sbjct: 135 NPTVSRVSAGAVEHMAIIRENNLVNTIKYLKQEGFWVLGADAKAR-QSYFNTSIPSPTAL 193

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           ++G E  GI +      D  + IPM G + SLN SVA+AL++YE  RQR N
Sbjct: 194 VIGGEGQGIRRLVRENCDILVRIPMFGQLNSLNASVAAALLIYEVLRQRLN 244


>UniRef50_C7PC85 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Chitinophaga pinensis
           DSM 2588 RepID=C7PC85_CHIPD
          Length = 197

 Score =  225 bits (575), Expect = 8e-58,   Method: Composition-based stats.
 Identities = 69/196 (35%), Positives = 115/196 (58%), Gaps = 4/196 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT- 59
           M P R  R+  +L +RQ  LTV +E V  PHN+SA++RT DAVG+ +V+ +   +  R  
Sbjct: 1   MTPERRERLLSVLNKRQAGLTVVLENVFDPHNISAVLRTCDAVGIQDVYVLNTTTARRKR 60

Query: 60  -MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
               +++ +  W+ V         +A ++ +  +I  THL+ +A    E+D+T    ++ 
Sbjct: 61  WGHKSSSSAAKWLTVHQFSDTATCMAVVREKYDKIYTTHLAADAKSLYELDFTGSVALVF 120

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSML 178
           G E+ G+++E   L D + IIP +G+++SLN+SVA A+ +YEA RQ+  AG Y ++N  L
Sbjct: 121 GNEQEGVSEEIRKLCDGNFIIPQVGIIKSLNISVACAVSIYEAMRQKSIAGHYEQKN--L 178

Query: 179 PEAEQQRLLFEGGYPV 194
           P+A+   LL E G+  
Sbjct: 179 PDAQYNALLEEWGFQE 194


>UniRef50_Q2JI19 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Synechococcus
           RepID=Q2JI19_SYNJB
          Length = 378

 Score =  225 bits (575), Expect = 9e-58,   Method: Composition-based stats.
 Identities = 51/179 (28%), Positives = 85/179 (47%), Gaps = 7/179 (3%)

Query: 2   NPTRYARICEMLARRQ----PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
            P +Y  + +++ R +      + V ++ +  PHN+ AI R+ +A G+  +      +  
Sbjct: 178 TPYQYVALEDLVERSRQAGPNPVLVVLDGIQDPHNLGAIARSVEAFGMQGMVIPQRRAAG 237

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T+   AAG+ S + V     +  A+ +LK QG  +  T  S  A      D+ RP  
Sbjct: 238 VTSTVMKVAAGALSTLPVARVVNLNRALEYLKEQGFWVYGTT-SRGADPIYSADFQRPIA 296

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRE 174
           +++G E  GI+       DQ + IP+ G  +SLN SVA+ + LYE  RQR    +   E
Sbjct: 297 LVVGSEGEGISLLTQRHCDQLLSIPLAGRTESLNASVAAGIALYEIHRQRSPHHLKRPE 355


>UniRef50_Q4L3J1 Putative trmH family tRNA/rRNA methyltransferase n=10 Tax=Bacilli
           RepID=TRMHL_STAHJ
          Length = 249

 Score =  225 bits (574), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 55/176 (31%), Positives = 88/176 (50%), Gaps = 7/176 (3%)

Query: 1   MNPTRYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P  YA   + +  ++        V ++ +  PHN+ +I+RTADA GV  V      S 
Sbjct: 73  IAPYEYADFDQFIQSQKDKEGLSTVVILDGLEDPHNLGSILRTADASGVDGVIIPKRRSV 132

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
              +T+A A+ G+   V V     +   +  LK  G  +     +DNA D+R++    P 
Sbjct: 133 ALTQTVAKASTGAIQHVPVMRVTNLAKTIDELKEHGYWVAGAE-ADNATDYRDMAADMPL 191

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGM 170
            I++G E  G+++      D  I IPM+G V SLN SVA++L++YE  R+R   G 
Sbjct: 192 AIVIGSEGQGMSRLVKDKCDFYIKIPMVGHVNSLNASVAASLMMYEVYRKRHQVGD 247


>UniRef50_Q7MH13 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=32
           Tax=Proteobacteria RepID=RLMB_VIBVY
          Length = 247

 Score =  224 bits (573), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 54/163 (33%), Positives = 80/163 (49%), Gaps = 3/163 (1%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAA 65
            + ++LA+    L + ++ V  PHN+ A +R ADA GV  V      S     T++  A 
Sbjct: 85  DLDDILAKHASPLLLILDGVTDPHNLGACLRNADAAGVAAVIVPKDKSAPMTATVSKVAC 144

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G+   V +     +   + HL+ QG+ I+ T   +   D  +   T    I+MG E  G+
Sbjct: 145 GAAETVPLVRVTNLARTMRHLQEQGIWIVGTA-GEATHDIYQAKLTGSLAIVMGAEGDGM 203

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
            +      D  I IPM G V SLNVSVAS + L+EA RQR  +
Sbjct: 204 RRLTRETCDDLIKIPMAGAVSSLNVSVASGICLFEAVRQRLAS 246


>UniRef50_A4BEK2 Putative tRNA methyltransferase n=1 Tax=Reinekea blandensis MED297
           RepID=A4BEK2_9GAMM
          Length = 224

 Score =  223 bits (570), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 85/218 (38%), Positives = 127/218 (58%), Gaps = 6/218 (2%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAA 64
           RY +  ++L +RQ D+T+  ++VHK  NVSAI+RTAD+VG+  VH V P          A
Sbjct: 5   RYLKFQQVLNQRQNDMTILTDKVHKSQNVSAIMRTADSVGIPTVHMVKPERGRLVYHHTA 64

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTG 124
            G++ +V V  + T+ + +  L+  GM + A H SD A+ +RE DYTRP  +++G EK G
Sbjct: 65  GGASRFVDVIVYETLSEGIQSLRNAGMALYAAHWSDRAISYREADYTRPFALILGAEKYG 124

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAE-- 182
           I+ EA   AD+ +IIPM+G  +SLNVSVAS +IL EA  QR     Y +    LP+ +  
Sbjct: 125 ISPEAADAADEHLIIPMVGACESLNVSVASGIILQEAMHQRMAQQAYTQ----LPDQDST 180

Query: 183 QQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADAD 220
               LF   +P +A     + LPYP +++ G++     
Sbjct: 181 YHNTLFRWLHPKMAAFCDARQLPYPQLDEDGDMIPPQG 218


>UniRef50_Q9JZR3 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=27
           Tax=Neisseria RepID=RLMB_NEIMB
          Length = 250

 Score =  222 bits (568), Expect = 6e-57,   Method: Composition-based stats.
 Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 4/160 (2%)

Query: 9   ICEMLAR-RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAA 65
           + ++L    +P L + ++ +  PHN+ A +RTADA+GVH V A    S     T++  A 
Sbjct: 85  LEDVLENLSEPPLLLILDGITDPHNLGACLRTADAMGVHAVIAPKDKSAGLNATVSKVAC 144

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G+   V   T   +   +  LK  G+ I+ T +S  + D    +       +MG E  G+
Sbjct: 145 GAAETVPYITVTNLARTLRELKEYGIWIIGTDMSGES-DLYHCNLPDSAAWVMGNEGDGM 203

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            +      D  + IPM G V+S+NVSV++ ++L E +RQR
Sbjct: 204 RRLTREHCDMLVSIPMFGTVESMNVSVSAGMVLSETRRQR 243


>UniRef50_B8IYB0 tRNA guanosine-2'-O-methyltransferase n=14 Tax=Desulfovibrionales
           RepID=B8IYB0_DESDA
          Length = 250

 Score =  222 bits (568), Expect = 6e-57,   Method: Composition-based stats.
 Identities = 81/191 (42%), Positives = 113/191 (59%), Gaps = 3/191 (1%)

Query: 2   NPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM- 60
              R AR+ E+LA RQPDLT+ +  +H PHNVSAI R+ DA GV  V+  +  +    + 
Sbjct: 60  TERRKARLLEVLAHRQPDLTLVLANIHDPHNVSAIYRSCDAFGVSRVNLYYTNTPFPALG 119

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              +A +  WV+   H+     +  L+GQ MQ+LAT  S  A   R+ D+TRPT ++MG 
Sbjct: 120 RKTSASARKWVESARHKDSAALMESLRGQNMQVLATSCSPTARPLRDWDFTRPTAVIMGN 179

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E +G+  E L +AD ++ IPM GM+QS NVSVA+A+IL EA RQR+ AGMY      +  
Sbjct: 180 EHSGVEPELLQMADGELYIPMYGMIQSFNVSVAAAIILSEAARQREAAGMY--ATPRMAA 237

Query: 181 AEQQRLLFEGG 191
           A  +  L E  
Sbjct: 238 AALEEKLQEWL 248


>UniRef50_C8P2I4 23S rRNA (Guanosine-2'-O-)-methyltransferase RlmB n=1
           Tax=Erysipelothrix rhusiopathiae ATCC 19414
           RepID=C8P2I4_ERYRH
          Length = 236

 Score =  222 bits (567), Expect = 6e-57,   Method: Composition-based stats.
 Identities = 54/168 (32%), Positives = 90/168 (53%), Gaps = 2/168 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MR 58
           +   +Y  + E++   + +L V  +Q+  PHN+ AI+RT DA GV  V      S     
Sbjct: 69  IQDYKYHSLQEIIKGAKNNLIVLCDQLEDPHNLGAILRTCDACGVDGVVVGKHRSVGLTS 128

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
           T+A  + G+ + V+V     +  A+A LK  G  ++A   + +AVD+ E +   P  +++
Sbjct: 129 TVAKVSTGAINTVKVAEATNMVKAIAELKEAGYWVVAAENAVDAVDYTEFNVDMPLVLVV 188

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           G E  GI++      D    IPM G V SLNVSVA+ ++L++  R+R+
Sbjct: 189 GSEGKGISRLVKKECDILTTIPMQGSVNSLNVSVATGVLLFDIVRRRK 236


>UniRef50_C9LMK8 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Dialister
           invisus DSM 15470 RepID=C9LMK8_9FIRM
          Length = 282

 Score =  222 bits (567), Expect = 7e-57,   Method: Composition-based stats.
 Identities = 56/170 (32%), Positives = 84/170 (49%), Gaps = 6/170 (3%)

Query: 1   MNPTRYARICEMLA--RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
           + P  YA + E+L+   R+  L + ++ V    N+ AI+RTA+  G   V      S   
Sbjct: 115 LKPYAYADLEEVLSSCERKDPLLILLDGVEDVRNIGAIVRTAECAGAAAVLLPKHRSSPV 174

Query: 59  TMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
           T A    A+G+ +++ V     I   +  LK +G   +   +     D  + D   P  I
Sbjct: 175 TAAAMKTASGAFAYLPVCQIGNIRQTLEKLKERGFWAVGADMDGG--DLYQADLKGPLVI 232

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           +MG E  GI+     + D  + IPM G V SLNVSVA+AL++YEA RQR 
Sbjct: 233 VMGAEGKGISPLTKRMCDFCVRIPMRGKVSSLNVSVAAALLMYEAVRQRN 282


>UniRef50_Q5HIE3 Putative trmH family tRNA/rRNA methyltransferase n=86
           Tax=Firmicutes RepID=TRMHL_STAAC
          Length = 248

 Score =  222 bits (567), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 54/175 (30%), Positives = 89/175 (50%), Gaps = 7/175 (4%)

Query: 1   MNPTRYARICEMLARRQPD----LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P  YA   + L +++        + ++ +  PHN+ +I+RTADA GV  V      S 
Sbjct: 73  IAPYEYADFDQFLKQQKEKEGLLTVLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSV 132

Query: 57  M--RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
              +T+A A+ G+   V V     +   +  LK  G  +  T  + NA D+R ++     
Sbjct: 133 TLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEAN-NATDYRNLEADMSL 191

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
            I++G E  G+++      D  I IPM+G V SLN SVA++L++YE  R+R + G
Sbjct: 192 AIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFRKRHDVG 246


>UniRef50_Q606P1 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Methylococcus
           capsulatus RepID=Q606P1_METCA
          Length = 250

 Score =  221 bits (565), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 48/168 (28%), Positives = 77/168 (45%), Gaps = 4/168 (2%)

Query: 3   PTRYARICEMLAR-RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRT 59
               A + + L       L + ++ V  PHN+ A +RT DA GV  +      S     T
Sbjct: 81  EQGEAELLDTLDAADGHPLYLVLDHVQDPHNLGACLRTCDAAGVKGLVVTKDQSVGLTPT 140

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
           +A  A+G+   V V     +   +   K +G  ++     +      E+D   P  ++MG
Sbjct: 141 VAKVASGAAETVPVYRVTNLARCLDRFKQRGYWVVGAA-GEAERTLYELDLRLPLVVVMG 199

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
            E  G+ +      D  + IPM+G V+SLN+SVA+ ++LYE  RQR  
Sbjct: 200 AEGVGLRRLTRERCDFLLRIPMVGGVESLNLSVATGIVLYEVMRQRSR 247


>UniRef50_B0TC37 RNA methyltransferase, trmh family n=1 Tax=Heliobacterium
           modesticaldum Ice1 RepID=B0TC37_HELMI
          Length = 256

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 50/170 (29%), Positives = 83/170 (48%), Gaps = 7/170 (4%)

Query: 1   MNPTRYARICEMLAR----RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG-- 54
           + P  Y  + E+L +     +P   + ++ +  PHN+ A++RTA+  G H V        
Sbjct: 79  VAPVAYVEVEEILEKAKAKGEPPFVLLLDGLEDPHNIGALLRTAEGAGAHGVIIPKRRGG 138

Query: 55  SRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
           +   T+A A+AG+  +V +     +   V  LK  G+ I+ + +      +   D+  P 
Sbjct: 139 AITSTVAKASAGAVEYVPIARVTNLVQTVGQLKKAGLWIIGSAMDA-PRPYFRQDFRGPV 197

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            +++G E  GI+       D  + IPM G V SLN SVA AL++YE  RQ
Sbjct: 198 GLIVGSEGKGISPLLREHCDHLVSIPMGGKVDSLNASVAGALLMYERVRQ 247


>UniRef50_A3DH38 RNA methyltransferase, TrmH family, group 3 n=14 Tax=Firmicutes
           RepID=A3DH38_CLOTH
          Length = 277

 Score =  220 bits (563), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 49/169 (28%), Positives = 85/169 (50%), Gaps = 7/169 (4%)

Query: 5   RYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MR 58
            Y  + ++L     + +    + ++ +   +N+ +I+RTADAVG H V      +     
Sbjct: 110 DYVEVDDILKIAQDKGEDPYIIILDGITDAYNLGSILRTADAVGAHGVVIPKRRAIGLNA 169

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
            ++ A+AG+  +V V     I   + +LK + + I+ T LS     F E D   P  +++
Sbjct: 170 AVSKASAGAIEYVPVARVTNISQTIEYLKKKNIWIVGTDLSGE-KPFFEADLKGPVALVI 228

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           G E  G+ +      D  + IPM G + SLN +VA+A+I+YE +RQR  
Sbjct: 229 GSEGEGMGRLVSEKCDFIVNIPMQGKISSLNAAVAAAIIMYEIRRQRNF 277


>UniRef50_B2UR21 RNA methyltransferase, TrmH family, group 3 n=3
           Tax=Chlamydiae/Verrucomicrobia group RepID=B2UR21_AKKM8
          Length = 193

 Score =  220 bits (563), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 49/159 (30%), Positives = 74/159 (46%), Gaps = 3/159 (1%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAG 66
           +  +L +    L + ++ V  PHN+ AI+RTAD  GV  V A    S     T+   + G
Sbjct: 35  LDGILDKSSNPLLLILDCVQDPHNLGAILRTADGAGVDAVIAPRDKSVGITETVLRVSVG 94

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           +   V       +   +  L+ +G+ I  T          E D+T P  ++MG E  G+ 
Sbjct: 95  AAEKVPFIQVTNLARTMKQLQSRGIWIFGTS-DKGDRGLYETDFTGPAALVMGAEGEGMR 153

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +      D  + IPM G +  LNVSVA+ + LYE  RQR
Sbjct: 154 RLTEENCDFLLRIPMKGSIPCLNVSVATGVCLYEMVRQR 192


>UniRef50_Q5HRM1 Putative trmH family tRNA/rRNA methyltransferase n=7
           Tax=Staphylococcaceae RepID=TRMHL_STAEQ
          Length = 249

 Score =  220 bits (563), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 55/173 (31%), Positives = 87/173 (50%), Gaps = 7/173 (4%)

Query: 1   MNPTRYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P  YA   E L +++        + ++ +  PHN+ +I+RTADA GV  V      S 
Sbjct: 73  VAPYEYANFDEFLQKQKKKARYSTVIILDGLEDPHNLGSILRTADASGVDAVIIPKRRSV 132

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
              +T+A A+ G+   V V     +   +  LK  G  I  T  + NA D+R++      
Sbjct: 133 ALTQTVAKASTGAIQHVPVIRVTNLSKTIDELKDNGFWIAGTEAN-NATDYRDLQADMSL 191

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
            I++G E  G+++      D  I IPM+G V SLN SVA++L++YE  R+R  
Sbjct: 192 GIVIGSEGQGMSRLVSDKCDFHIKIPMVGHVNSLNASVAASLMMYEVYRKRHQ 244


>UniRef50_Q1G8Z2 TRNA/rRNA methyltransferase n=109 Tax=Bacilli RepID=Q1G8Z2_LACDA
          Length = 255

 Score =  220 bits (562), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 49/164 (29%), Positives = 83/164 (50%), Gaps = 4/164 (2%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMAS 62
            + ++ + L + +  L + ++ +  PHN+ +I+R+ADA GV  V      +      +A 
Sbjct: 92  DFDQLLDKLDQEEAPLLLMLDNIEDPHNLGSILRSADATGVSGVIIPKRRASGLTSVVAK 151

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
            + G+   V V     +      LK +G  I  T +  +  D+R+ +    T +++G E 
Sbjct: 152 TSTGAIDHVPVARVNNLVQTCQALKDRGYWIFGTAMEGD--DYRKWNANGKTVLVIGNEG 209

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            GI+   L   DQ + IPMIG VQSLN SVA+ ++LY+A   R 
Sbjct: 210 KGISPLLLKQMDQTLTIPMIGHVQSLNASVATGVLLYQAFNSRH 253


>UniRef50_A0L4P9 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Magnetococcus
           sp. MC-1 RepID=A0L4P9_MAGSM
          Length = 246

 Score =  220 bits (562), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 45/162 (27%), Positives = 78/162 (48%), Gaps = 2/162 (1%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM--ASA 63
           +  + +++ + +  L V ++ V  PHN+ AI+R+A+A G   V      +         A
Sbjct: 83  WDDLLDVVEKAKQPLLVILDGVEDPHNLGAIMRSAEAFGALAVILPKDRTAPLNAGAIKA 142

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           +AG+   + +     +  A+  L+ + + ++       A     +D   P  ++MG E +
Sbjct: 143 SAGAAERLDLIRVTNLARAIEQLQQRNVWVIGLAGEAGAPLIGTLDCKGPLALVMGNEGS 202

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           G+ +      DQ   IPM G V SLNVSVA+ + LYE  RQR
Sbjct: 203 GLRRLTRERCDQLAAIPMGGGVGSLNVSVATGVALYEVLRQR 244


>UniRef50_B2A4B9 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Natranaerobius
           thermophilus JW/NM-WN-LF RepID=B2A4B9_NATTJ
          Length = 247

 Score =  220 bits (562), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 55/172 (31%), Positives = 88/172 (51%), Gaps = 8/172 (4%)

Query: 3   PTRYARICEML-----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           P +Y+++  +L       ++P   + ++ +  P N  AIIRTADAVGV  V      S  
Sbjct: 77  PFKYSQLDTVLKGFDYNNQKPLTLLILDHLTDPQNFGAIIRTADAVGVDGVIIPKRRSVD 136

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T+  A++G+   V +     +   ++ LK Q + IL T +  +     E +Y  P  
Sbjct: 137 VNPTVMKASSGAAEHVPIIKVSNLRQTISKLKEQWIWILGTDIDGD-RGIFEENYNIPLA 195

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           +++G E +G++       D    IPMIG V SLN SVA+A++LYE  RQ+ N
Sbjct: 196 LVVGNEASGMSPLVKKECDFIANIPMIGRVNSLNASVATAVVLYEIYRQKTN 247


>UniRef50_C5CF29 RNA methyltransferase, TrmH family, group 3 n=7 Tax=Thermotogaceae
           RepID=C5CF29_KOSOT
          Length = 250

 Score =  220 bits (561), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 38/169 (22%), Positives = 74/169 (43%), Gaps = 7/169 (4%)

Query: 1   MNPTRYARICEMLAR---RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           +    Y  +  +L +   ++  L V ++++  PHN+ AIIR++ A G   V      S  
Sbjct: 75  LKEFPYTSLETLLDKIMEKKRSLLVLLDRIQDPHNLGAIIRSSVAAGADGVIITEKASVE 134

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
               +   + G    + +     +   +  LK +G    A  +      +  + +T    
Sbjct: 135 VTPAVVKVSTGLVFRIPIVRVVNMARTIETLKEEGFWTYAATMEGE--PYYSVSFTDKAA 192

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           ++ G E  GI       +D  + IPM   + SLNV+ ++A++L+E +RQ
Sbjct: 193 LIFGNEGKGIRHLVKKKSDYLVSIPMCEGIDSLNVAASAAIMLFEYRRQ 241


>UniRef50_B8D0A6 RNA methyltransferase n=11 Tax=Firmicutes RepID=B8D0A6_HALOH
          Length = 244

 Score =  219 bits (560), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 48/169 (28%), Positives = 81/169 (47%), Gaps = 5/169 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MR 58
           ++P     I     + +    + ++QV  PHN+ AIIRTA A G H +      S     
Sbjct: 78  VSPREMVEIAR--EKGEDPFIIILDQVQDPHNLGAIIRTAYAAGAHGLIYPRKRSADITP 135

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
            +  A+AG+ + + +     I   +A LK  G+ I  T +      +   DY  P  +++
Sbjct: 136 VVTKASAGAVNHLPLAKVSNINYTIADLKDMGLWITGTDVRG-TRPYYSADYKGPVGLVI 194

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           G E  G+ +      D  + IPM G + SLN SVA+ ++++E  RQR++
Sbjct: 195 GNEGKGMRRLVKENCDFVVNIPMSGELGSLNASVAAGVVIFEVVRQRRS 243


>UniRef50_C4V0H0 tRNA/rRNA methyltransferase n=1 Tax=Selenomonas flueggei ATCC 43531
           RepID=C4V0H0_9FIRM
          Length = 272

 Score =  219 bits (559), Expect = 6e-56,   Method: Composition-based stats.
 Identities = 53/175 (30%), Positives = 89/175 (50%), Gaps = 7/175 (4%)

Query: 1   MNPTRYARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P  Y  + E++A    R +  L + ++ +  P N+ A++RTADA GVH +      S 
Sbjct: 97  VAPVAYVAVEEVIAGARARGEDPLLLLLDGIEDPQNLGALLRTADAAGVHGILLPRRHSV 156

Query: 57  M--RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T+A  +AG+  +V V     I   +  LK QG  I    +    + +   + T   
Sbjct: 157 PLTETVARVSAGALEYVPVARIGNIAQTIRALKEQGFWIAGADMGGEEI-YDRANLTGAL 215

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
            +++G E  G+++    L D  + +PM+G + SLN SVA A+++YEAQRQR+   
Sbjct: 216 VLVIGSEGRGMSRLTRDLCDFTVRLPMMGKINSLNASVAGAILMYEAQRQRRAKA 270


>UniRef50_B2IX93 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Nostoc
           punctiforme PCC 73102 RepID=B2IX93_NOSP7
          Length = 363

 Score =  219 bits (558), Expect = 8e-56,   Method: Composition-based stats.
 Identities = 48/176 (27%), Positives = 79/176 (44%), Gaps = 6/176 (3%)

Query: 2   NPTRYARICEMLARRQP---DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS--R 56
            P  Y  + +++ + +     + V  + +  PHN+ AIIRTA+A+G   +      +   
Sbjct: 179 APYGYIELADLIEQSKSVTDPVIVVADGITDPHNLGAIIRTAEAIGAQGLVIPQRRASGI 238

Query: 57  MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
             T+   AAG+     V     +  A+  LK  G  I  T  S  +     +++  P  +
Sbjct: 239 TSTVMKVAAGALENFTVSRVVNLSRALEELKEAGFWIYGTAASG-SEPVHTVNFKGPIVL 297

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYL 172
           ++G E  G+        D  + IP+ G   SLN SVA+ + LYE  RQR    +YL
Sbjct: 298 VIGSEGEGLGMLTQRSCDFLVSIPLQGKTPSLNASVAAGMALYEIYRQRSLNTLYL 353


>UniRef50_Q7MBB6 tRNA/rRNA methyltransferase n=1 Tax=Gloeobacter violaceus
           RepID=Q7MBB6_GLOVI
          Length = 338

 Score =  219 bits (558), Expect = 9e-56,   Method: Composition-based stats.
 Identities = 45/170 (26%), Positives = 77/170 (45%), Gaps = 3/170 (1%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMAS 62
            +  +   L  R   + +  + +  PHN+ A+IR+A+A G   +      +     T+A 
Sbjct: 169 EFEELIASLVERPDPVLLAADGIEDPHNLGALIRSAEAFGFQGIILPQRRAVGVTATVAK 228

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
            AAG+   + +     +  A+  LK  G Q++ T     +    E+    P  +++G E 
Sbjct: 229 VAAGAVEHLPIARVTNLNQAIERLKEAGYQVVGT-QEKASQALYELKLDGPLVVVVGSEG 287

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYL 172
            GI+       D  + IP+ G   SLN SVA  ++LYE  RQR+   + L
Sbjct: 288 KGISLLTQRHCDHMVSIPLAGKTTSLNASVAGGIMLYEVMRQRRANQIDL 337


>UniRef50_Q06753 Putative trmH family tRNA/rRNA methyltransferase yacO n=86
           Tax=Bacteria RepID=YACO_BACSU
          Length = 249

 Score =  218 bits (557), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 49/175 (28%), Positives = 87/175 (49%), Gaps = 7/175 (4%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           +    YA + ++      + +    + ++++  PHN+ +I+RTADAVG H +      + 
Sbjct: 75  VAAYEYAELDDLYKAAEEKNEQPFFLILDELEDPHNLGSIMRTADAVGAHGIVIPKRRAV 134

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T+A A+ G+   + V     +   +  +K +G+ ++ T  S    DFR +D   P 
Sbjct: 135 GLTTTVAKASTGAIEHIPVARVTNLARTLEEMKERGIWVVGTDASARE-DFRNMDGNMPL 193

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
            +++G E  G+ +      D  I +PM G V SLN SVA+ L++YE  R+R   G
Sbjct: 194 ALVIGSEGKGMGRLVKEKCDFLIKLPMAGKVTSLNASVAAGLLMYEVYRKRNPVG 248


>UniRef50_C3RMB5 23S rRNA methyltransferase n=5 Tax=Bacteria RepID=C3RMB5_9MOLU
          Length = 244

 Score =  218 bits (557), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 53/171 (30%), Positives = 89/171 (52%), Gaps = 6/171 (3%)

Query: 1   MNPTRYARICEMLAR---RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           +   RY  I E++      +  L + ++ +  PHN+ AI+RT DA+GV  V      S  
Sbjct: 73  IEEYRYYSIDEIINTIPDGKQPLLLMLDGLEDPHNLGAILRTCDAIGVDGVIIGKNRSVG 132

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T+A  + G+   V+V     +   +  LK +   ++   L D + D+R++DY  P  
Sbjct: 133 LNGTVAKVSTGAIDHVKVAQVTNLTRTLEDLKKRSFWVVGCDL-DKSQDYRQVDYNMPLV 191

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           I++G E  GI++      D ++++PM+G V SLN SVA+A+ILY+    R 
Sbjct: 192 IVIGSEGFGISRLVKKSCDINVVLPMVGHVNSLNASVATAVILYQVYNSRN 242


>UniRef50_A4XJ85 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Clostridia
           RepID=A4XJ85_CALS8
          Length = 253

 Score =  218 bits (557), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 46/173 (26%), Positives = 81/173 (46%), Gaps = 7/173 (4%)

Query: 3   PTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVH--AVWPGSR 56
             +Y  I ++L     + +    V ++++  PHN  +IIR+A   G H +   A      
Sbjct: 74  EYKYWDIDDLLLEAANKGEKPFLVLLDEITDPHNFGSIIRSAHLCGAHGIITEARNSCPI 133

Query: 57  MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
             T+  A+AG+   ++V     +   +  LK +G+ + A   +       + D+  P CI
Sbjct: 134 TPTVEKASAGAIEHIKVARVVNLRRTIDSLKEKGVWVYAADNNAE-KFVYDCDFKIPICI 192

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
           ++G E  GI++     AD  + IP  G + S N SVA+ +I +E  +QR   G
Sbjct: 193 IIGSEGKGISRLVKEGADFLVKIPQKGKINSYNASVAAGIIFFEVLKQRMQEG 245


>UniRef50_Q1ISZ4 RNA methyltransferase TrmH, group 3 n=2 Tax=Acidobacteria
           RepID=Q1ISZ4_ACIBL
          Length = 261

 Score =  218 bits (556), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 46/186 (24%), Positives = 84/186 (45%), Gaps = 6/186 (3%)

Query: 5   RYARICEMLARR--QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTM 60
            Y  + +++ ++  +    V ++ +  PHN+ A+IR+AD  GV  V      +     T 
Sbjct: 77  EYLDLDDIIEKKRGEHAFVVVLDGIEDPHNLGALIRSADGAGVDGVVIPERRAVGVTGTA 136

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQ-GMQILATHLSDNAVDFREIDYTRPTCILMG 119
             A+AG+  +V +     I  ++  LK +  +  +         ++ EIDY     +++G
Sbjct: 137 MKASAGAAEYVPIARVTNIARSIEDLKDKYNVWTVGLD-ERGTQNYDEIDYNMSLALVLG 195

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E  G+        D  + IPM G V SLNVSVA  +++YE  RQR+             
Sbjct: 196 AEGKGLHDLVRKKCDLLVKIPMAGEVSSLNVSVAGGIVMYEVSRQRRAKVAGAGSPGTTS 255

Query: 180 EAEQQR 185
           + + ++
Sbjct: 256 KKKNRK 261


>UniRef50_B8G1U5 RNA methyltransferase, TrmH family, group 3 n=4 Tax=Firmicutes
           RepID=B8G1U5_DESHD
          Length = 246

 Score =  217 bits (555), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 50/171 (29%), Positives = 82/171 (47%), Gaps = 8/171 (4%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P  YA + ++L     + +    + +++V  PHN+ A+IRTADA GVH V      S 
Sbjct: 74  VAPREYAEVDDILALAGEKGEDPFILVLDEVEDPHNLGALIRTADAAGVHGVIIPKRRSV 133

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T+A  +AG+   V V     +   +  L+  G  +         V     D T   
Sbjct: 134 SLTATVAKTSAGAVEHVLVARVGNLVQTLKDLQKAGCWVSGAEAEGTEV--YRSDLTGAR 191

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            I++G E  G+++      D+ + +PM G + SLN SVA ++++YE  RQR
Sbjct: 192 VIVIGSEGKGLSRLVKETCDEIVSLPMKGRINSLNASVAGSILMYEVLRQR 242


>UniRef50_B9L1B3 tRNA guanosine-2'-O-methyltransferase n=3 Tax=Bacteria
           RepID=B9L1B3_THERP
          Length = 217

 Score =  217 bits (555), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 84/210 (40%), Positives = 124/210 (59%), Gaps = 13/210 (6%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           +   R AR+ E+LARRQPDLTV +E VH PHNVSA++R+ DAVG+  VH V+       +
Sbjct: 5   ITERRLARMREVLARRQPDLTVVLENVHDPHNVSAVLRSCDAVGLLRVHLVYTLEEFPEL 64

Query: 61  A-SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSD--NAVDFREIDYTRPTCIL 117
           + + +  +  W+++  H +I      L+ QG  I  T+L D   +VD  ++D T+P  ++
Sbjct: 65  SENVSGSALKWLELVFHPSIEACYRTLRSQGFTIYTTYLGDPARSVDLYDLDLTKPVALV 124

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSM 177
            G E+ G++ EA+A AD + +IPM+GMV+SLN+SVA A+ LYEA RQR+ AG Y R    
Sbjct: 125 FGNEQRGVSDEAVAGADGNFVIPMMGMVRSLNISVACAVSLYEALRQRRLAGHYAR--PK 182

Query: 178 LPEAEQQRLLFEGGYPVLAKVAKRKGLPYP 207
           L   E +  L            +R+G   P
Sbjct: 183 LSPIELEERLQRWL--------EREGRALP 204


>UniRef50_C5NV68 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Gemella
           haemolysans ATCC 10379 RepID=C5NV68_9BACL
          Length = 271

 Score =  217 bits (554), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 50/165 (30%), Positives = 86/165 (52%), Gaps = 5/165 (3%)

Query: 1   MNPTRYARICEM---LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM 57
           + P  Y  + E+   L   +    + ++ +  PHN+ AIIRTA+A GV  +      + +
Sbjct: 101 VAPYSYFELDEVVNNLEINKDTTLLILDHIEDPHNLGAIIRTAEASGVKAIIIPKRRAAV 160

Query: 58  --RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
             +T   A+AG+   + V     + DA+  LK +G  I  T L++ + D+ +I    P  
Sbjct: 161 VSQTAVKASAGAIEHMPVIRVSNLTDAIKKLKEKGFWIAGTTLAERSEDYTKIAKDVPLA 220

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYE 160
           I++G E  G+++      D    +PM+G +QSLN SVA+ +I+YE
Sbjct: 221 IVIGNEGEGMSKVVTNECDFLYHLPMLGKIQSLNASVAAGIIMYE 265


>UniRef50_B8HJN1 RNA methyltransferase, TrmH family, group 3 n=6 Tax=Bacteria
           RepID=B8HJN1_CYAP4
          Length = 387

 Score =  217 bits (553), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 50/177 (28%), Positives = 83/177 (46%), Gaps = 6/177 (3%)

Query: 1   MNPTRYARICEMLARRQ---PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           + P  Y  +  +L   Q     + +  + +  PHN+ AIIRTA+A+G   +      +  
Sbjct: 198 VAPYSYLELDTLLENIQGLDHPVLLAADGITDPHNLGAIIRTAEALGAQGLVVPQRRAVG 257

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T+A  AAG+     V     +  A+  LK  G  I     +  A     ++++ P  
Sbjct: 258 ITSTVAKVAAGALEHFAVARVVNLNQALEQLKAAGFWIYGMAATA-AKPIYSVEFSGPVV 316

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYL 172
           +++G E TG++  A    DQ + IP++G   SLN SVA+ + LYE  RQR +  +  
Sbjct: 317 LVVGAEGTGLSLLAQRYCDQLVSIPLLGKTPSLNASVATGMALYEIFRQRSSTSVRQ 373


>UniRef50_Q82XD1 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=112
           Tax=Proteobacteria RepID=RLMB_NITEU
          Length = 260

 Score =  217 bits (553), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 50/167 (29%), Positives = 80/167 (47%), Gaps = 4/167 (2%)

Query: 4   TRYARICEMLAR-RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTM 60
            RYA + ++L    +P L + ++ V  PHN+ A +R ADA GVH V      +     T+
Sbjct: 80  RRYATLEDLLEGLTEPALLLVLDGVKDPHNLGACLRVADAFGVHAVVVPKDRAVGLSATV 139

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A+G+   V       +   +  LK  G+ I+ T  +D       +  TRP   ++G 
Sbjct: 140 HKVASGAVDTVPFFAVTNLARTLRELKEMGLWIVGTA-ADAPDTLDSVTLTRPLAWVLGA 198

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           E  G+ +      D  + IPM G ++SLNVSV++ + L+E  RQ   
Sbjct: 199 EDGGMRRLTREACDLLVSIPMSGSIESLNVSVSAGICLFETFRQHSQ 245


>UniRef50_B3QM30 RNA methyltransferase, TrmH family, group 3 n=12 Tax=Chlorobiaceae
           RepID=B3QM30_CHLP8
          Length = 257

 Score =  217 bits (553), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 59/169 (34%), Positives = 92/169 (54%), Gaps = 5/169 (2%)

Query: 1   MNPTRYARICEMLARRQP--DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM- 57
           +    +  + E+LA  +    L V ++ +  PHNV AIIRTA+AV    V  +       
Sbjct: 88  LTSVTFYTLDEVLAAPRNSSPLLVILQGLEDPHNVGAIIRTAEAVAADSVIMIEGKGAPI 147

Query: 58  -RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
             T+  A+AG+ S ++V   +++   +  L  +G  I+A  +     +  +ID+ RPT +
Sbjct: 148 SATVHKASAGALSHMRVCKVKSLVKTLDLLHERGFSIVAADMEAE-HNHTDIDWKRPTVL 206

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +MG E  G+  E     DQ + IPM G V+SLNVSVA+ ++LYEA RQR
Sbjct: 207 VMGAEGKGLGSETRKRCDQIVRIPMAGCVESLNVSVAAGVMLYEAMRQR 255


>UniRef50_Q88DE7 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=285
           Tax=Proteobacteria RepID=RLMB_PSEPK
          Length = 248

 Score =  217 bits (553), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 46/153 (30%), Positives = 74/153 (48%), Gaps = 3/153 (1%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAAGSNSWVQV 73
             P L + ++ V  PHN+ A +RTADA G   V      S      +   A G+   + +
Sbjct: 94  ETPPLILVLDGVTDPHNLGACLRTADAAGATAVIVPKDKSATLTPVVRKVACGAAEVIPL 153

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALA 133
                +   +  L+ +G+ ++ T   +   +  + D T P  ++MG E  G+ +      
Sbjct: 154 VAVTNLARTLEKLQQRGLWVVGTA-GEAEQEIYQQDLTGPLVMIMGAEGKGMRRLTREHC 212

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           D  + +PM G V SLNVSVA+ + L+EA RQRQ
Sbjct: 213 DFLVKLPMAGSVSSLNVSVATGVCLFEAVRQRQ 245


>UniRef50_Q7NYX3 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=23
           Tax=Proteobacteria RepID=RLMB_CHRVO
          Length = 248

 Score =  217 bits (553), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 53/164 (32%), Positives = 82/164 (50%), Gaps = 4/164 (2%)

Query: 5   RYARICEMLAR-RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMA 61
            Y  + ++L    +P L + ++ V  PHN+ A +R ADA+G H V A    S     T++
Sbjct: 81  NYVDLDDVLENLSEPPLLLILDGVTDPHNLGACLRVADAMGAHAVIAPKDRSATLNATVS 140

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
             A G+   V   T   +   +  LK  G+ I  T +  +  D    D + P   +MG E
Sbjct: 141 KVACGAAEVVPYITVTNLARTLRDLKDAGVWIAGTTMEAD-TDLYHFDASGPLAWVMGAE 199

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             G+ +      D  + IPM G V+SLNVSV+S ++L E++RQR
Sbjct: 200 GEGMRRLTREHCDVLVSIPMFGTVESLNVSVSSGMVLSESRRQR 243


>UniRef50_A2U211 SpoU rRNA methylase family protein n=1 Tax=Polaribacter sp. MED152
           RepID=A2U211_9FLAO
          Length = 229

 Score =  217 bits (553), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 60/216 (27%), Positives = 102/216 (47%), Gaps = 8/216 (3%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           +   R     ++LA R    TV +E +++PHN SA++RT D  GV ++H +      R  
Sbjct: 18  LTDKRKQTFQKVLAERTRHFTVVLEDIYQPHNASAVVRTCDIFGVQDLHVIENRYINRVS 77

Query: 61  ASAAAGSNSWVQVKTH----RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
                G+  W+  K +          + HLK  G QI+AT    +A   ++    + T  
Sbjct: 78  KYVTKGAQKWITTKRYKTDGDNTKTCLNHLKTAGYQIIATSPHADANLLQDFKIDKKTAF 137

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENS 176
           + G E TGI+      AD  + IPM+G  +S N+SVA+A+IL +   + +N+    R + 
Sbjct: 138 VFGAEATGISDTVKEHADGFLKIPMVGFTESFNISVAAAIILQDVTTRLKNS----RIDW 193

Query: 177 MLPEAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQ 212
           ML   E+++L  +     +  V K +   Y  +  +
Sbjct: 194 MLSNDEKEQLYLQWIKETIKNVTKIEERFYQQLEDE 229


>UniRef50_C8WTZ2 RNA methyltransferase, TrmH family, group 3 n=2
           Tax=Alicyclobacillus acidocaldarius RepID=C8WTZ2_ALIAD
          Length = 255

 Score =  216 bits (552), Expect = 4e-55,   Method: Composition-based stats.
 Identities = 56/169 (33%), Positives = 87/169 (51%), Gaps = 5/169 (2%)

Query: 1   MNPTRYARICEMLARRQ--PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
           + P  Y  + +++ R      L V ++++  PHN  AI+RTA+A G   V          
Sbjct: 87  VAPYAYVDLDDVIRRDTGFAPLVVVLDEIADPHNFGAILRTAEASGAQGVVIGKRRQAQV 146

Query: 59  T--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
           T  +A AAAG+   + V     +  A+  LK  G  I+   +    V + E+DY  PT +
Sbjct: 147 TDVVAKAAAGALETLPVARVANVAQALQRLKQAGYWIVGADVEAK-VPYTEVDYRGPTAV 205

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           ++G E  G+ +      D  + IP++G VQSLN SVA+ ++LYEA RQR
Sbjct: 206 VIGSEGQGMRRWVREQCDFLVSIPILGRVQSLNASVAAGVLLYEAVRQR 254


>UniRef50_Q1D7V2 RNA methyltransferase, TrmH family, group 3 n=7 Tax=Bacteria
           RepID=Q1D7V2_MYXXD
          Length = 282

 Score =  216 bits (551), Expect = 5e-55,   Method: Composition-based stats.
 Identities = 53/168 (31%), Positives = 82/168 (48%), Gaps = 7/168 (4%)

Query: 4   TRYARICEMLAR----RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--M 57
            +YA + ++L       QP L V ++ +  PHN+ AIIR+ADA+G H V      +    
Sbjct: 110 FKYAELEDLLEAAKALGQPPLVVVLDGIQDPHNLGAIIRSADALGAHGVVIAKDRAVQVT 169

Query: 58  RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
            T+A A+AG+    ++     I  A+  LK  G+ + A  +              P  ++
Sbjct: 170 GTVAKASAGAVEHSRIARVVNISRALEELKEAGLWVAAADVDAKE-PMWSARLDGPLALV 228

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +G E  G+    L   D  + IPM G V SLN SV++ ++LYE  RQR
Sbjct: 229 VGAEGAGVRDGVLKHCDFRLRIPMAGQVGSLNASVSAGILLYEVARQR 276


>UniRef50_C7H0N3 RNA methyltransferase, TrmH family n=1 Tax=Eubacterium saphenum
           ATCC 49989 RepID=C7H0N3_9FIRM
          Length = 297

 Score =  215 bits (550), Expect = 7e-55,   Method: Composition-based stats.
 Identities = 44/168 (26%), Positives = 80/168 (47%), Gaps = 8/168 (4%)

Query: 6   YARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRT 59
           Y  I + L     R +  L + ++++  P N+ AIIRTA   GVH +      +     T
Sbjct: 131 YRDIDDALRLADIRGEKPLVLVLDRIEDPRNLGAIIRTARCAGVHGIIIAKDRAAGITPT 190

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
           +A  + G+   +       +  A+  LK +G  + A   + ++    E ++     +++G
Sbjct: 191 VAKVSEGAIFSIPCIMVTNLAAALKDLKQRGFWVYAADANGDS--CFEQEFGGSVALVLG 248

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
            E  GI++  L  +D  + IPM+    SLNVSVA+ +++YE  R+   
Sbjct: 249 NEGKGISKLCLNESDYKVSIPMVNDFDSLNVSVAAGILMYEIVRKNNR 296


>UniRef50_Q73MR5 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Treponema
           denticola RepID=Q73MR5_TREDE
          Length = 258

 Score =  215 bits (550), Expect = 7e-55,   Method: Composition-based stats.
 Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 4/163 (2%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASA 63
                  LA +     V ++ V  PHN  +IIR+AD  G+  +      S      ++  
Sbjct: 97  VDEFFAKLAEKGSAFVVILDSVTDPHNTGSIIRSADQFGIDGIIVPENKSAGGFEIISKV 156

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           +AG+ +WV       +   V  LK +G  I        A+    + + + T ++MG E  
Sbjct: 157 SAGALAWVPFVEVTNLVRTVERLKKEGFWIYGADAGGKALP--NLTFPKKTVLIMGNEGR 214

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           G+++      D+ + IP  G + SLNVSVA+ ++LYE  R+++
Sbjct: 215 GMSRLVEETCDEIVSIPTKGKLDSLNVSVAAGILLYEISRKKE 257


>UniRef50_C7REQ2 RNA methyltransferase, TrmH family, group 3 n=4 Tax=Anaerococcus
           RepID=C7REQ2_ANAPD
          Length = 234

 Score =  215 bits (549), Expect = 8e-55,   Method: Composition-based stats.
 Identities = 43/147 (29%), Positives = 72/147 (48%), Gaps = 3/147 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSNSWVQVKTHRT 78
            + ++++  PHN+ AIIR+A++ G   V      S     T+   +AG+ + ++V     
Sbjct: 86  LIILDKIEDPHNLGAIIRSAESFGFDAVIIPERRSASVTSTVYKTSAGAINNIKVVRVTN 145

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           +   +  LK +G  I       ++ D    D      +++G E  GI++      D  I 
Sbjct: 146 LTRTIKDLKDKGFWIYGLAGEAHS-DISHADLRGKVGLVVGNEGEGISRLVRENCDMLIN 204

Query: 139 IPMIGMVQSLNVSVASALILYEAQRQR 165
           IPM+G V SLN SVA+A+ +YE  RQ 
Sbjct: 205 IPMLGRVNSLNASVAAAISMYELLRQN 231


>UniRef50_A8RFN1 Putative uncharacterized protein n=2 Tax=Erysipelotrichaceae
           RepID=A8RFN1_9FIRM
          Length = 241

 Score =  215 bits (549), Expect = 9e-55,   Method: Composition-based stats.
 Identities = 51/171 (29%), Positives = 84/171 (49%), Gaps = 6/171 (3%)

Query: 1   MNPTRYARICEMLA---RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           ++  +   I E++A   + +  L V ++++  PHN+ AI+RT D VGV  V         
Sbjct: 70  IDDYKTYTIEELVAGVPKGKTPLFVMLDELEDPHNLGAILRTCDCVGVDGVIIGKHRGVK 129

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T+A  + G+   V+V     +   +  LK +G  +      DN+ D+R+  Y  P  
Sbjct: 130 LTPTVAKVSTGAIDTVKVAVVTNLAQTLKGLKKEGFWVAGADF-DNSQDYRQASYDMPLV 188

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           +++G E  GI+       D  + +PM G V SLN SVA A++LY+   QR 
Sbjct: 189 LVVGSEGFGISPLVKKNCDFFVRLPMEGSVSSLNASVACAVLLYQIYAQRN 239


>UniRef50_B5EQA2 RNA methyltransferase, TrmH family, group 3 n=3
           Tax=Acidithiobacillus RepID=B5EQA2_ACIF5
          Length = 255

 Score =  215 bits (548), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 49/166 (29%), Positives = 80/166 (48%), Gaps = 5/166 (3%)

Query: 4   TRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP--GSRMRTMA 61
             +  I   L        + ++ V  PHN+ A +R+A+A GV  V            T+ 
Sbjct: 80  QDFEAILAQLNG--CGFLLVLDGVLDPHNLGACLRSAEAAGVDAVILPRDNACPVNATVR 137

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
            A+AGS S V V T   +   ++ L+  G  ++     + +     +D   P  ++MG E
Sbjct: 138 KASAGSASRVPVCTVTNLSRTLSSLQEAGFWLVGMA-GEGSRSLYALDLDMPLVMVMGGE 196

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           + G+ +      D    IPM+G ++SLNVSVA+ + L+EA RQR+N
Sbjct: 197 EKGLRRLTREHCDYLAHIPMMGAIESLNVSVATGICLFEAARQRRN 242


>UniRef50_Q2LQ81 23S rRNA Gm2251 methyltransferase n=1 Tax=Syntrophus aciditrophicus
           SB RepID=Q2LQ81_SYNAS
          Length = 249

 Score =  215 bits (548), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 45/170 (26%), Positives = 78/170 (45%), Gaps = 7/170 (4%)

Query: 2   NPTRYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
              RY  +  ++A R P    DL + ++ +  PHN+ A+IR+A   G + +      +  
Sbjct: 74  TAYRYQDLDAVIANRHPSCPYDLVLILDGILDPHNLGALIRSAHCFGANGIILPERRAAS 133

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T+   +AG+   + +     +  A+  LK +G  I       +     + DY     
Sbjct: 134 VTGTVIKTSAGAARHIPIARVANLARALDELKTKGFWIFGADARAD-QSVSDPDYQGAVG 192

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           ++MG E  G+        D  I IPM+G + SLNVSV+  +IL+E +R+ 
Sbjct: 193 LVMGGESKGLRPLIRKKCDDLISIPMLGKIDSLNVSVSGGIILHEIRRKN 242


>UniRef50_A8PMQ1 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Rickettsiella
           grylli RepID=A8PMQ1_9COXI
          Length = 253

 Score =  215 bits (548), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 45/152 (29%), Positives = 70/152 (46%), Gaps = 3/152 (1%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAGSNSWVQVK 74
            P   + ++ V  PHN+ A +R+A+A GV  V      +  +T      AAG+     + 
Sbjct: 103 NPPFLLVLDGVQDPHNLGACLRSANAAGVDAVIIPQDRAVNKTPIVQKTAAGAAEVTSLF 162

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALAD 134
           T   +   +  LK  G+       S       +   T P  +++G E  G+ +      D
Sbjct: 163 TVTNLATCLERLKKCGIWCYGLDQSG-TRLIYDAPLTGPLALVLGAEGKGLRRLTKVCCD 221

Query: 135 QDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
             + IPM+G V SLNVSVA+ + L+E  RQRQ
Sbjct: 222 DLVAIPMVGTVGSLNVSVAAGVGLFEVVRQRQ 253


>UniRef50_A6BKK3 Putative uncharacterized protein n=6 Tax=Bacteria
           RepID=A6BKK3_9FIRM
          Length = 265

 Score =  215 bits (548), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 44/173 (25%), Positives = 80/173 (46%), Gaps = 8/173 (4%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           +    YA + +ML     + +    + ++ +  PHN+ AIIRTA+  G H V      + 
Sbjct: 95  VAAYEYAEVEDMLKLAEEKGEDPFLIILDNIEDPHNLGAIIRTANQAGAHGVIIPKRRAV 154

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T+A  +AG+ ++  V     +   +  LK +G+  +   +  +     +++   P 
Sbjct: 155 GLTATVARTSAGALNYTPVAKVTNLVKTMEDLKKKGLWFVCADMDGD--VMYDVNMKGPI 212

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
            +++G E  G+ +      D    IPM G + SLN SVA+ ++ YE  RQR  
Sbjct: 213 GLVIGNEGEGVGRLVKDTCDFTARIPMKGDIDSLNASVAAGVLAYEIVRQRMQ 265


>UniRef50_A7B5E9 Putative uncharacterized protein n=7 Tax=Bacteria
           RepID=A7B5E9_RUMGN
          Length = 275

 Score =  214 bits (547), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 41/174 (23%), Positives = 74/174 (42%), Gaps = 10/174 (5%)

Query: 2   NPTRYARICEMLA-------RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG 54
            P     +   +               + ++ +  P N+  I RTA+A GV  +      
Sbjct: 102 TPQGVLAVVHQMEYTLGQMTEGAIPHLMILDNLQDPGNLGTIFRTAEAAGVTGIIMSRDC 161

Query: 55  SRMRTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR 112
             +       +  G+   +       + + +  LK + ++  A HL      + + DY +
Sbjct: 162 VDIYNPKTIRSTMGALYRMPFVYVEDLRETIHTLKEKNIKSYAAHLDGKNT-YDKEDYRQ 220

Query: 113 PTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            T  L+G E  G+ +E    AD  I IPM G V+SLN +VA+ ++++E  RQR+
Sbjct: 221 GTAFLIGNEGNGLREEIAQCADTWIRIPMCGQVESLNAAVAATVLMFEVSRQRR 274


>UniRef50_A1HPG2 TRNA/rRNA methyltransferase (SpoU) n=1 Tax=Thermosinus
           carboxydivorans Nor1 RepID=A1HPG2_9FIRM
          Length = 270

 Score =  214 bits (547), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 55/170 (32%), Positives = 90/170 (52%), Gaps = 4/170 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR-- 58
           +   +     + L     +L V ++ V  P NV  ++RTADA G   V      + +   
Sbjct: 101 VMEKKRYTFDD-LQSSDRELIVVLDNVQDPGNVGTVVRTADAAGCCGVILTKGCADLFSG 159

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
               A  GS   + V T     +  A L+ QG+++LAT L  +++ + ++D   P  I+ 
Sbjct: 160 KTVRATMGSLFHLPVITGVAEQEVAAFLERQGIRLLATALDSSSL-YHDVDLRSPVAIVF 218

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           G E  G+++  L  AD+ + IP+ G  +SLNV+VA+A+ILYEA+RQR+ A
Sbjct: 219 GNEGAGVSKVILEKADERLYIPLYGRAESLNVAVAAAVILYEARRQRRVA 268


>UniRef50_C2BF70 tRNA/rRNA methyltransferase n=1 Tax=Anaerococcus lactolyticus ATCC
           51172 RepID=C2BF70_9FIRM
          Length = 239

 Score =  214 bits (546), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 42/167 (25%), Positives = 77/167 (46%), Gaps = 6/167 (3%)

Query: 4   TRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMA 61
             Y  + ++    +    + ++Q+  PHN+ AIIR+A++ G   V      S      + 
Sbjct: 77  FEYKDLRDL---DKYQRLIILDQIEDPHNLGAIIRSAESFGFDGVIIPERRSASVSPIVY 133

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
             +AG+ + + +   +    A+  +K  G  +      + +    ++D     C+++G E
Sbjct: 134 KTSAGAINNINIIMVKNTNRAIEEIKEAGFWVYGLA-GEASSPIDQVDLKGKVCLIVGNE 192

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
             G+++      D  I IPM G V SLN SVASA+ +YE  RQ   +
Sbjct: 193 GKGLSRLVRENCDILINIPMKGFVNSLNASVASAIAMYEVLRQNGFS 239


>UniRef50_B8I1W5 RNA methyltransferase, TrmH family, group 3 n=5 Tax=Clostridium
           RepID=B8I1W5_CLOCE
          Length = 269

 Score =  214 bits (546), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 15/177 (8%)

Query: 2   NPTRYARICEMLARRQPDL---------TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW 52
            P     I  ++ + +             V ++ +  P N   IIRTADA G+  V    
Sbjct: 93  TPQG---ILAVIKKNKYSFDKVITEGSSVVILDCLQDPGNAGTIIRTADAAGISAVLMSK 149

Query: 53  PGSRMR--TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDY 110
               +    +  +  GS   + +     I + +  LK    +++A+HLS    ++ + D 
Sbjct: 150 GCVDLYSPKVLRSTMGSVFHIPIFEGLNITEIIRVLKQNDYKVIASHLSGK-NNYFQEDL 208

Query: 111 TRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           T  + I++G E  GI+ E   +AD  + IPM G  +SLN SVA+++++YE  RQ+ +
Sbjct: 209 TGRSAIIVGNEANGISDETAYMADSLVKIPMPGKAESLNASVAASVMIYEIVRQKSH 265


>UniRef50_C8WR00 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Bacillales
           RepID=C8WR00_ALIAD
          Length = 256

 Score =  214 bits (546), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 64/194 (32%), Positives = 93/194 (47%), Gaps = 3/194 (1%)

Query: 12  MLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWV 71
           +L RR   + V ME V   HN +AI+R+A+A GV  V  +              G++ W+
Sbjct: 41  VLMRRTSYIAVAMEAVDDGHNQAAILRSAEAFGVQHVAVIEGKQPFHPSKGVTQGAHKWL 100

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            ++    IG A+  L  +G Q+ AT L + A     +D  RPT IL G EK G++ EA  
Sbjct: 101 TLQRMPDIGRAIDALHARGFQVYATDLGEGAQPIDAVDLARPTAILFGNEKDGVSPEARE 160

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAEQQRLLFEGG 191
            AD    IPM G VQS NVSVA+A+ LYE  R+ +     + +   L   E+ +L     
Sbjct: 161 RADGRFYIPMAGFVQSFNVSVAAAIALYELTRRARET---VGDRYALGADERHKLYVTWC 217

Query: 192 YPVLAKVAKRKGLP 205
              L    + +   
Sbjct: 218 LRSLHGATREEARR 231


>UniRef50_B0P8C0 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0P8C0_9FIRM
          Length = 256

 Score =  214 bits (545), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 49/154 (31%), Positives = 78/154 (50%), Gaps = 4/154 (2%)

Query: 14  ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSNSWV 71
           AR +P L V  + +  PHN+ AIIRTA+A G H +     G       +   +AG+   +
Sbjct: 102 ARGEPPLLVIADSIEDPHNLGAIIRTAEAAGAHGLIIPKRGGAGLTAIVGRTSAGAVEHL 161

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            V     +   +  LK +G+ I     S     + + D T P+ +++G E  G+++    
Sbjct: 162 PVARVTNLVSTIKELKARGVWIYGADASGAR--WDQTDLTGPSALVIGSEGFGLSRLVRE 219

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             D  + +PM G V SLN SVA+ +++YEA RQR
Sbjct: 220 TCDALLSLPMRGEVNSLNASVAAGILMYEAVRQR 253


>UniRef50_A1APM1 RNA methyltransferase, TrmH family, group 3 n=8
           Tax=Desulfuromonadales RepID=A1APM1_PELPD
          Length = 251

 Score =  214 bits (545), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 42/169 (24%), Positives = 70/169 (41%), Gaps = 7/169 (4%)

Query: 1   MNPTRYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP--G 54
           + P  YA + +++            + ++ +  PHN+ A+IRTA   G   V        
Sbjct: 74  VAPFSYADLDDLIEAGDREDAAGFLLVLDGIQDPHNLGALIRTAACAGASGVVIPRDRAC 133

Query: 55  SRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
           +       A+AG+   + V     I  ++  LK  G  +       +A    E+ ++   
Sbjct: 134 AITPAAEKASAGAVETITVAQVTNIAQSLEKLKRSGYWVYGLSGEADA-SLYEVAFSGKI 192

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
            +++G E  GI        D  + IP+ G V SLN SVA  + LYE  R
Sbjct: 193 ALVIGGEGEGIRPLVRKQCDALVSIPLYGGVGSLNASVAGGIALYEVAR 241


>UniRef50_D1AP92 RNA methyltransferase, TrmH family, group 3 n=7
           Tax=Fusobacteriaceae RepID=D1AP92_SEBTE
          Length = 234

 Score =  213 bits (544), Expect = 4e-54,   Method: Composition-based stats.
 Identities = 41/169 (24%), Positives = 78/169 (46%), Gaps = 7/169 (4%)

Query: 1   MNPTRYA-RICEMLAR---RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++   Y   + E L +   +Q  + + ++Q+  P N  AIIR+A+  GV  +      S 
Sbjct: 65  VSEYDYYLELNEFLEKVLAKQRSIVLVLDQIQDPRNFGAIIRSAECFGVDGIIIQDRNSV 124

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T+  ++ G+   V +     + D++  LK  G  I          ++    +    
Sbjct: 125 SVTETVVKSSTGAIEHVDIIKVTNVSDSMDKLKKYGYFIYGAEADGE-TEYYNEPFPEKL 183

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           C+++G E  G+ ++     D+ + IPM G + SLNVSVA+ ++L E  +
Sbjct: 184 CLVLGSEGKGMRKKVKEHCDKILNIPMHGKINSLNVSVANGILLAEISK 232


>UniRef50_Q83CW6 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=19
           Tax=Proteobacteria RepID=RLMB_COXBU
          Length = 250

 Score =  213 bits (543), Expect = 4e-54,   Method: Composition-based stats.
 Identities = 48/164 (29%), Positives = 80/164 (48%), Gaps = 4/164 (2%)

Query: 7   ARICEMLARRQPD-LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASA 63
           + +  +L +R+   L + ++ V  PHN+ A +R+A+A GV  V A    +      +   
Sbjct: 84  SALLSLLKKRETPALLLILDGVKDPHNLGACLRSANAFGVRAVIAPKDRAVGVTPVVRKV 143

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           A G+           +   +  L+ +G+ I+ T +    +  +EID T    I++G E  
Sbjct: 144 ACGAAEMTPFIRVTNLSRTIDWLQKEGVWIVGTAVEAETL-IQEIDLTGDIAIVLGSEGA 202

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           G+ +      D    IP+ G V+SLNVSVA  + LYE QRQR+ 
Sbjct: 203 GLRRLTKERCDFLAQIPLRGSVESLNVSVACGICLYEVQRQREA 246


>UniRef50_A7HLT3 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Thermotogaceae
           RepID=A7HLT3_FERNB
          Length = 234

 Score =  212 bits (542), Expect = 6e-54,   Method: Composition-based stats.
 Identities = 45/151 (29%), Positives = 72/151 (47%), Gaps = 4/151 (2%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM--ASAAAGSNSWVQV 73
            +    V ++QV  P N+ AI+RTA A GV+ V      S   T     A+AG+   + +
Sbjct: 82  PENPFIVLLDQVQDPQNLGAIVRTAVAAGVNMVVLTKDNSAHVTPGSIKASAGTIFRIPI 141

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALA 133
                +   +  LK +G+ I    +        E+   RP  I+ G E +GI Q      
Sbjct: 142 VITVNLARYIEKLKDKGVWIYGADMRG--KPLWEVKLERPLGIVFGNEGSGIRQLVKESC 199

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           D+ + IPM   + SLNVSV++ +++YE  R+
Sbjct: 200 DELVSIPMKTPIDSLNVSVSAGILIYEVLRR 230


>UniRef50_Q1LSR1 RNA methyltransferase, TrmH family, group 3 n=4
           Tax=Gammaproteobacteria RepID=Q1LSR1_BAUCH
          Length = 248

 Score =  211 bits (539), Expect = 1e-53,   Method: Composition-based stats.
 Identities = 45/165 (27%), Positives = 82/165 (49%), Gaps = 3/165 (1%)

Query: 7   ARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAA 64
             +  +LA+    L + ++ V  PHN+ A +R ADA GV+ +      S     T+   A
Sbjct: 84  QDLPALLAQHTAPLLLVLDGVTDPHNLGACLRCADAAGVNAIIIPRNRSAYLNATVKKVA 143

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFRE-IDYTRPTCILMGQEKT 123
           +G+   + +     +   +  L+   + IL T +  ++  ++    +T P  +++G E  
Sbjct: 144 SGAAETMPLIQVTNLARTLRLLQEHNILILGTTIEADSHIYQTSFKFTSPIALVVGAEGN 203

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           GI +      ++ + IPM+G V SLNVSVA  + L+E  RQR ++
Sbjct: 204 GIRRLTKKYCNELLRIPMVGSVASLNVSVAVGVFLFEVVRQRLSS 248


>UniRef50_C9RX94 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Geobacillus
           RepID=C9RX94_GEOSY
          Length = 247

 Score =  211 bits (539), Expect = 1e-53,   Method: Composition-based stats.
 Identities = 73/208 (35%), Positives = 116/208 (55%), Gaps = 9/208 (4%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           + P R  R+ E+L  R   +TV +E V  PHN +A++RTA+A GV +VH V   +     
Sbjct: 30  ILPRRLRRMYEVLNERTRYITVLIEAVDDPHNQAAVLRTAEAFGVQDVHIVTGKAPFSPN 89

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
                 ++ W+ +     I  A+A LK QG Q+ A++L +  +   +ID ++PT +L G 
Sbjct: 90  RLVTRYADQWLTLHHKPDIKTAIADLKSQGYQVYASYLGEGTIPVSDIDLSQPTALLFGN 149

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ-RQRQNAGMYLRENSMLP 179
           E +G+++EAL LAD   +IPM G VQS N+SVA+AL LY+   R R+ AG     +  L 
Sbjct: 150 EHSGVSEEALRLADGTFVIPMYGFVQSFNISVAAALALYDVTERARRQAG----RHYYLL 205

Query: 180 EAEQQRLLFEGGY----PVLAKVAKRKG 203
             E++ L  +  +    P + K  +++G
Sbjct: 206 PGEKKALYEQWMWQTLNPRIRKQLQQQG 233


>UniRef50_B2V596 RNA methyltransferase, TrmH family n=7 Tax=Clostridium
           RepID=B2V596_CLOBA
          Length = 262

 Score =  211 bits (538), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 49/169 (28%), Positives = 83/169 (49%), Gaps = 6/169 (3%)

Query: 2   NPTRYARICEMLARR---QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
           NP     I +M  ++   Q D  +  ++V  P N+  IIRTA A GV+ +        + 
Sbjct: 91  NPQGIIAIVKMNNKKLDFQGDFYLFCDKVQDPGNLGTIIRTAHAAGVNGIVLSKGTVDIY 150

Query: 59  T--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
                 +  GS  ++ +         +  LK  G  ++ T L +++ DF + D      +
Sbjct: 151 NEKTIRSTMGSLFYMPIYYDDDEFSLIKSLKKDGFTLIVTSL-ESSKDFFKEDLKGKIIL 209

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            +G E  G++ E L LAD+ + IPM G  +SLNV++A+++I+YE  RQ 
Sbjct: 210 TVGNEGNGVSNEVLDLADRRVKIPMPGGAESLNVAIATSIIIYEKVRQN 258


>UniRef50_A6CBV4 YacO n=1 Tax=Planctomyces maris DSM 8797 RepID=A6CBV4_9PLAN
          Length = 261

 Score =  211 bits (538), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 45/172 (26%), Positives = 86/172 (50%), Gaps = 6/172 (3%)

Query: 1   MNPTRYARICEMLARRQ--PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP--GSR 56
           M P  Y  I E+  +++    L + ++++  P N  AIIR+A+ +G   + +        
Sbjct: 92  MAPFPYTSI-ELFNQQEITSPLFLILDRIQDPFNFGAIIRSAEIMGADGIFSGTHEQCEV 150

Query: 57  MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
              +   +AG+ + V +     +       K  G+ I+ T +  +     + ++ +PT +
Sbjct: 151 TSLVCRTSAGAVNHVPLVQATDLVSLCRDWKQNGINIVGTAMQASEK-LNDYNFQQPTAV 209

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           ++G E TGI+ E  A     + IP  G  +SLNV+V+++++LYEA RQR  +
Sbjct: 210 IVGNEGTGISPELQAECTHLVRIPQQGKTESLNVAVSASILLYEASRQRNFS 261


>UniRef50_A6Q996 tRNA (Guanosine-2'-O-)-methyltransferase n=2
           Tax=Epsilonproteobacteria RepID=A6Q996_SULNB
          Length = 216

 Score =  210 bits (537), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 85/209 (40%), Positives = 122/209 (58%), Gaps = 7/209 (3%)

Query: 2   NPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVH-AVWPGSRMRTM 60
           +  R  RI ++L  +QP L V ++ VH   N+SAI+RT DAVGV  ++        +R  
Sbjct: 10  SQERIDRIDQILCCKQPTLKVMLDDVHSSQNLSAILRTCDAVGVQHLYYTTSDNRDLRIH 69

Query: 61  ASAAAGSNSWVQVKTHRTIGD--AVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
            +   G++ WV+     T      +   + +G Q++ THL + AV FRE+DYT+PT I+M
Sbjct: 70  KTITQGAHRWVERTRISTEEQRVFLQKKQKEGYQVVVTHLEERAVPFREVDYTKPTIIVM 129

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSML 178
           G EK G++ E + LAD  IIIPM GMVQSLNVSVA+ALILYEA+RQ   AG Y  +   L
Sbjct: 130 GNEKDGVSSETVELADTVIIIPMQGMVQSLNVSVAAALILYEAERQLAEAGKY--DTPQL 187

Query: 179 PEAEQQRLLFEGGYPVLAKVAKRKGLPYP 207
            + E++++     Y     +A+R     P
Sbjct: 188 SKEEREKIKSGWLYRD--NIARRSKGKIP 214


>UniRef50_A8STN2 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A8STN2_9FIRM
          Length = 272

 Score =  210 bits (537), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 38/150 (25%), Positives = 70/150 (46%), Gaps = 4/150 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTHRT 78
            + ++ +  P N+  I R+A+A G+  V             +  +  G+   V       
Sbjct: 122 YLILDTIQDPGNMGTIFRSAEAAGITGVIIGPGSCDPYNPKVVRSTMGAIFRVPFVQSDD 181

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           +   +  LK +G+ I   HL        + ++      L+G E  G+++     AD+ + 
Sbjct: 182 LIYTIDALKRKGVLIYGAHLDGEE--LYDTEFPDKIAFLIGNEGNGLSKAVSDTADRLLR 239

Query: 139 IPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           IPM G V+SLN ++++ L+ YEA RQR++A
Sbjct: 240 IPMEGKVESLNAAISATLLSYEAMRQRRSA 269


>UniRef50_C4L0U6 tRNA guanosine-2'-O-methyltransferase n=4 Tax=Bacillales
           RepID=C4L0U6_EXISA
          Length = 254

 Score =  210 bits (536), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 74/208 (35%), Positives = 119/208 (57%), Gaps = 7/208 (3%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           + P R  R+ E+L  R   +T+  E V  PHN SA++R+ADA GV  +H V   ++ +  
Sbjct: 39  LMPDRIKRMYEVLNTRTNHITILTEGVDDPHNQSAVLRSADAFGVQTLHVVEGRAKFKPN 98

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
           +  A  ++ WV V  H +I +A+  LK  G Q+ AT LS+ A+   E+D ++PT +L G 
Sbjct: 99  SIIAKSADRWVDVVEHGSIEEAIDALKESGYQVYATALSEEAIPLEEVDVSKPTVLLFGN 158

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E +G+++ AL  AD + +IPM G VQSLN+SVA+A+ LY+   + ++    + +   LP 
Sbjct: 159 EHSGVSETALHKADGNFVIPMQGYVQSLNISVAAAISLYDVTTRSRH---IVTDGYELPV 215

Query: 181 AEQQRLLFEGGYPVLAKV----AKRKGL 204
            +Q R+  +     L K      K+KG+
Sbjct: 216 EDQARIFKDWMVKSLPKRTLGLYKQKGV 243


>UniRef50_Q1NS81 RNA methyltransferase TrmH, group 3 n=3 Tax=Deltaproteobacteria
           RepID=Q1NS81_9DELT
          Length = 302

 Score =  210 bits (536), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 3/156 (1%)

Query: 14  ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAAGSNSWV 71
           A   P L + ++ +  PHN+ A++R+A A GV  V      S     T+  AAAG+ + +
Sbjct: 141 AAGPPPLLLVLDSLQDPHNLGAVLRSAAAFGVDGVILPKDRSAPLSGTVLKAAAGTAALL 200

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            +     +  A+  LK  G  I      + + +  E D+T PTC+++G E+ GI      
Sbjct: 201 DICRTTNLAGALGTLKKHGFWIYGAS-GEASGNLYETDFTGPTCLVLGNEQKGIRPLLKK 259

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
             D  + IP+   V+SLNVSVA+ ++L E +R++  
Sbjct: 260 HCDFLLAIPLAAGVESLNVSVAAGIMLAEIRRRQHF 295


>UniRef50_B7DP24 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Alicyclobacillus
           acidocaldarius LAA1 RepID=B7DP24_9BACL
          Length = 249

 Score =  210 bits (536), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 65/194 (33%), Positives = 93/194 (47%), Gaps = 3/194 (1%)

Query: 12  MLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWV 71
           +L RR   + V ME V   HN +AI+R+A+A GV  V  +      +       G++ W+
Sbjct: 37  VLMRRTGYIAVAMEAVDDGHNQAAILRSAEAFGVQHVAVIEGKQPFQPSKGVTQGAHKWL 96

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            +    ++G A+  L  +G Q+ AT L D A     +D  RPT IL G EK G++ EA  
Sbjct: 97  TIHRMPSVGRAIDALHARGFQVYATDLGDGAEPIDAVDLARPTAILFGNEKDGVSPEARE 156

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPEAEQQRLLFEGG 191
            AD    IPM G VQS NVSVA+A+ LYE  R+ +       +   L   E+ RL     
Sbjct: 157 RADGRFYIPMAGFVQSFNVSVAAAIALYELTRRARETA---GDRYALDADERHRLYVTWC 213

Query: 192 YPVLAKVAKRKGLP 205
              L    + +   
Sbjct: 214 LRSLHGATREEARR 227


>UniRef50_C6CVT7 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Bacillales
           RepID=C6CVT7_PAESJ
          Length = 264

 Score =  210 bits (536), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 51/175 (29%), Positives = 83/175 (47%), Gaps = 10/175 (5%)

Query: 2   NPTRYARICEMLAR------RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS 55
            P     + E L R      R   L V ++ V  P NV  IIR+ADAVG   V       
Sbjct: 92  TPPPVFAVLEKLKRDDTALFRNNSLVVVLDGVRDPGNVGTIIRSADAVGADAVVLGKGSV 151

Query: 56  RMRTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
            +       +  GS   + +     + + +   + +G++++ T L      +   D+T  
Sbjct: 152 DLYNPKTVRSTMGSLFHLPIIE-ADLAELLPEAQSKGIKLVGTSLQATHTCY-TYDWTAG 209

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           T +LMG E  G++       D+ +IIPM G  +SLNV++A+ ++LYEA RQR+ +
Sbjct: 210 TWLLMGNESEGLSDAVRLAVDESVIIPMQGEAESLNVAMAATVLLYEAVRQRKYS 264


>UniRef50_Q14PR4 Putative trna/rrna methyltransferase protein n=1 Tax=Spiroplasma
           citri RepID=Q14PR4_SPICI
          Length = 244

 Score =  210 bits (536), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 57/163 (34%), Positives = 88/163 (53%), Gaps = 4/163 (2%)

Query: 3   PTRY--ARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MR 58
           P  Y  A I     + +    + ++Q+  PHN  AI+RT D   V  V  +         
Sbjct: 77  PQNYSLASITTKALQNKHPFLLVLDQISDPHNFGAILRTCDLFNVDGVIILDKRQVDINA 136

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
           T+A  +AG+ ++V V     + +A+ +LK QG  I AT L+  A +  E+ Y  P C+++
Sbjct: 137 TVAKTSAGAFNYVPVCRVNNLTNAIEYLKKQGFWIYATSLNTKAQNVSELKYDIPICLIV 196

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEA 161
           G E TGI+ + L  AD +I IP  G + SLNVSVASA+++Y+ 
Sbjct: 197 GNEGTGISAKLLKHADFNIYIPTAGHLDSLNVSVASAILIYQI 239


>UniRef50_Q724H1 RNA methyltransferase, TrmH family, group 3 n=21 Tax=Firmicutes
           RepID=Q724H1_LISMF
          Length = 251

 Score =  210 bits (535), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 48/164 (29%), Positives = 87/164 (53%), Gaps = 7/164 (4%)

Query: 8   RICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMA 61
            + ++ A    + +    + ++++  PHN+ +I+RTAD+VG H +      S    +T+A
Sbjct: 84  ELDDLFAAAEAKDEMPFFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVA 143

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
            A+ G+  +V V     +   +  L+ +G+ I  T  +  + D+R +D   P  I++G E
Sbjct: 144 KASTGAMEYVPVVRVTNMVRTMEELQKRGLWIFGTD-AKGSSDYRTMDVDMPLAIVIGSE 202

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             G++       D  + +PM G V SLN SVA++L+LYE  R+R
Sbjct: 203 GFGMSCLVREKCDFLVHLPMRGKVTSLNASVAASLLLYEVYRKR 246


>UniRef50_Q1JXE5 RNA methyltransferase TrmH, group 3 n=1 Tax=Desulfuromonas
           acetoxidans DSM 684 RepID=Q1JXE5_DESAC
          Length = 244

 Score =  210 bits (535), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 48/171 (28%), Positives = 76/171 (44%), Gaps = 5/171 (2%)

Query: 1   MNPTRYARICEMLARRQPD--LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
           +    +  + ++LA+        + ++ +  PHN  A+IR+A A G   V      S   
Sbjct: 72  VKAQDFVSLAQLLAQSSQSERFFLILDGITDPHNFGALIRSAAAAGCQGVIFAKDRSCPV 131

Query: 59  T--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
           T  +   AAG+  +VQ+     +G A+  LK  G+ +      +      E   + P  +
Sbjct: 132 TGIVEKTAAGTLGYVQLCQVTNLGRAIEELKKAGVWVYGLAGEEG-QSLFEAPLSAPIAL 190

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           + G E  GI      L D  I IPM G V+SLNVSVA+ + L+E  R    
Sbjct: 191 VAGSEGRGIRPLIRKLCDGLIAIPMPGRVESLNVSVATGIALFEVVRNHLK 241


>UniRef50_A2C1X9 RNA methyltransferase TrmH, group 3 n=6 Tax=Cyanobacteria
           RepID=A2C1X9_PROM1
          Length = 442

 Score =  209 bits (534), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 47/183 (25%), Positives = 85/183 (46%), Gaps = 6/183 (3%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAG 66
           I    A     L + ++ +  P N+ AIIR+A+A+G   +      S     ++A  AAG
Sbjct: 260 IDACKAFGDSSLLLALDGLTDPQNLGAIIRSAEALGAQGLILPQRRSAGLTGSVAKVAAG 319

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           +   + V     +  ++  LK +G  ++     + +    EI +  P  +++G E  GI+
Sbjct: 320 ALEHLPVARVVNLNRSLEKLKDEGYTVVGLA-EEGSSTLSEIKFQGPLVVVVGSEDKGIS 378

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ---RQNAGMYLRENSMLPEAEQ 183
                L DQ + IP+ G+  SLN SVA+++ LYE  R    R  +G       + P+   
Sbjct: 379 LITRRLCDQLVRIPLKGVTTSLNASVATSIFLYEVARSKWMRSISGQDPSPRLLKPQISS 438

Query: 184 QRL 186
           +++
Sbjct: 439 EKI 441


>UniRef50_C1F8Y2 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Acidobacterium
           capsulatum ATCC 51196 RepID=C1F8Y2_ACIC5
          Length = 270

 Score =  209 bits (534), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 46/163 (28%), Positives = 76/163 (46%), Gaps = 3/163 (1%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASA 63
              +    A   P L + ++ V  P N+ A++R+AD  GV  V      S          
Sbjct: 85  IEDLMAAPADGHPHLLLALDGVEDPQNLGALLRSADGAGVDGVLLPERRSAPLSAVAVKT 144

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           +AG+   +++     +  A+  LK Q +  +        + +   D+T P+ +++G+E  
Sbjct: 145 SAGAAEHIRIARVVNLVRALEQLKEQNIWCVGLD-ERGTMSYDAYDWTTPSVVVLGREGE 203

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           G+        D  + IPM G V SLNVS A A++LYEA RQR+
Sbjct: 204 GLHDLVRKTCDHLVRIPMAGGVSSLNVSAAGAVVLYEAARQRR 246


>UniRef50_A1AWI4 RNA methyltransferase, TrmH family, group 3 n=3
           Tax=Gammaproteobacteria RepID=A1AWI4_RUTMC
          Length = 247

 Score =  209 bits (534), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 45/152 (29%), Positives = 77/152 (50%), Gaps = 3/152 (1%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQV 73
                 + ++ +  P N+ A +R+A+A GVH V     GS      +   +AG+ + +++
Sbjct: 95  DNAGFILILDSIQDPRNLGACLRSANAAGVHCVVINKNGSAPINSLVHKTSAGALNQLKI 154

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALA 133
                +   +  L+ + + ++    S N +   +ID T P  I+MG E +G+ +      
Sbjct: 155 FQVTNLSRTIKALQQKNIWVIGLDGSVN-ISIYQIDLTIPNAIIMGAEGSGLRRLTKQSC 213

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           DQ   IPM G V+SLNVSVA+ + L+E  RQR
Sbjct: 214 DQLAKIPMQGKVESLNVSVATGVTLFEVNRQR 245


>UniRef50_Q0EVP7 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Mariprofundus
           ferrooxydans PV-1 RepID=Q0EVP7_9PROT
          Length = 247

 Score =  209 bits (533), Expect = 6e-53,   Method: Composition-based stats.
 Identities = 47/166 (28%), Positives = 79/166 (47%), Gaps = 4/166 (2%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR---MRTMAS 62
           +    + +      + + ++QV  PHN+ A +RTA+A G   V  +   +       +A 
Sbjct: 83  FEAWLKTVDMETAPMVLLLDQVTDPHNLGACVRTAEAAGCAAVIVLKDHAADVHSPVVAK 142

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
           AA G+ S + V     +   +  L+ QG   +     +  +   +   +  T ++MG E 
Sbjct: 143 AACGALSRLPVLRVINMKRCIEQLQQQGFWTVGLA-GEAELSIYDAKLSGATAVVMGSED 201

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
            G+ +      DQ I IPM G+V+SLNVSVA+ + L+E  RQR  A
Sbjct: 202 KGVRRLVRETCDQLIHIPMPGVVESLNVSVATGVALFEINRQRVTA 247


>UniRef50_A4GI27 rRNA methyltransferase n=1 Tax=uncultured marine bacterium
           EB0_41B09 RepID=A4GI27_9BACT
          Length = 246

 Score =  209 bits (533), Expect = 7e-53,   Method: Composition-based stats.
 Identities = 46/165 (27%), Positives = 77/165 (46%), Gaps = 5/165 (3%)

Query: 5   RYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTM 60
           +Y  + +++     +P L + ++ V  P N+ A  R ADA+GV  +      +     T+
Sbjct: 82  KYVTVEDIIEENYDKPLLFLILDGVVDPQNLGACFRVADAMGVDALICPKDNAVGLNATV 141

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A G    V       +   + +LK   + +  T  + N    ++ ++     ++MG 
Sbjct: 142 RKVACGGAESVPFVVVTNLARTIRYLKNSNVFVYGTDDNAN-KSLQKTNFKGSIALVMGS 200

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           E  G+ +    L D    IPM+G V+SLNVSVAS + LYE  RQR
Sbjct: 201 EGKGMRRLTNELCDDIFSIPMMGQVESLNVSVASGICLYEINRQR 245


>UniRef50_B9ZJH8 RNA methyltransferase, TrmH family, group 3 n=1
           Tax=Thioalkalivibrio sp. K90mix RepID=B9ZJH8_9GAMM
          Length = 251

 Score =  209 bits (532), Expect = 8e-53,   Method: Composition-based stats.
 Identities = 53/170 (31%), Positives = 77/170 (45%), Gaps = 5/170 (2%)

Query: 2   NPTRYARICEMLARRQP--DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--M 57
            P        ++ R +   DL + ++ V  PHN+ A +RTADA G   +      S    
Sbjct: 83  APRPVVEEKALVQRVRNGLDLVLVLDGVTDPHNLGACLRTADAAGAGAIVTPRHHSAALT 142

Query: 58  RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
                 A+G+   V V     +   +A LK  GM  +         D   +D   PT I+
Sbjct: 143 PAAIKVASGAAETVPVVAVGNLARTLAALKDAGMWTVGLD-GAAHEDLYAVDLRPPTAIV 201

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           MG E  G+ +      D    IPM G V+SLNVSVA+ + L+EA+RQR+ 
Sbjct: 202 MGAEGEGMRRLTREACDHLARIPMGGTVESLNVSVATGITLFEARRQRRA 251


>UniRef50_Q31FJ2 RNA methyltransferase TrmH, group 3 n=1 Tax=Thiomicrospira
           crunogena XCL-2 RepID=Q31FJ2_THICR
          Length = 244

 Score =  209 bits (532), Expect = 9e-53,   Method: Composition-based stats.
 Identities = 48/163 (29%), Positives = 78/163 (47%), Gaps = 3/163 (1%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAA 65
            +  +L      L + +++V  PHN+ AI+RTADA GV  V      S     T+   A 
Sbjct: 83  DLKALLEAESNPLFLFLDEVQDPHNLGAILRTADATGVTAVVIPKHNSVGVNATVRKVAC 142

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G+   V+V     +   +  L+  G+ +       N     ++D+     ++MG E +G+
Sbjct: 143 GAAETVKVVVVSNLVRTIKELQQAGLWVTGLAGETNTT-LYQLDFKGAVGLVMGAEGSGL 201

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
            +      D    IPM G ++SLNVSVA+ ++LYE  RQR  +
Sbjct: 202 RKLTRETCDHLAAIPMAGSIESLNVSVATGVVLYEVYRQRLQS 244


>UniRef50_D2REE3 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Archaeoglobus
           profundus DSM 5631 RepID=D2REE3_ARCPR
          Length = 232

 Score =  207 bits (528), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 41/168 (24%), Positives = 79/168 (47%), Gaps = 6/168 (3%)

Query: 1   MNPTRYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR-- 56
           ++P  Y  +  ++ +  R+    + ++ V  P N+ AI+R+A+  G   V          
Sbjct: 63  ISPIEYKEVDTIIDKCIREGSFILFLDSVEDPQNMGAIMRSAEFFGCAGVVIPKRRCVQV 122

Query: 57  MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
             T+A  +AG+   + +     + + +  LK  G+ ++   L       R +D + P  I
Sbjct: 123 NETVAKVSAGAVFHLDIARVENLANILKKLKKFGITVVGADLDGE--PLRNVDLSPPLAI 180

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           ++G E  G+++      D    I   G + SLN+SVA A+I+YE +R+
Sbjct: 181 VVGGEDKGLSKPVKKQCDFIAKIEGYGKINSLNLSVAGAIIMYEFRRR 228


>UniRef50_C2KW83 Possible RNA methyltransferase n=1 Tax=Oribacterium sinus F0268
           RepID=C2KW83_9FIRM
          Length = 260

 Score =  207 bits (527), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 42/155 (27%), Positives = 75/155 (48%), Gaps = 3/155 (1%)

Query: 14  ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAAGSNSWV 71
            + + DL + +E +  P N+  + RTA+A GV+ +             +  +  GS   +
Sbjct: 101 EKPKGDLFLILENIQDPGNLGTLFRTAEAAGVNHIFLSRNTVDPFSPKVVRSTMGSLFRL 160

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
                  +      LK  G+Q+ A  L        +  +  P+  L G E  G+T+E   
Sbjct: 161 PFSIEEDLFFLCESLKSAGVQVFALDLDGKKT-HFQAAFQGPSAFLFGNEGNGLTKELSQ 219

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            A + ++IPM G ++SLNV+ +++++LYEA RQR+
Sbjct: 220 CATEKLLIPMEGKIESLNVATSASIVLYEAVRQRR 254


>UniRef50_Q6FF50 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=19
           Tax=Moraxellaceae RepID=RLMB_ACIAD
          Length = 248

 Score =  206 bits (526), Expect = 4e-52,   Method: Composition-based stats.
 Identities = 55/161 (34%), Positives = 84/161 (52%), Gaps = 3/161 (1%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAA 65
            + ++L      L + ++QV  PHN+ A IRTA A+G+  V      S     T    AA
Sbjct: 86  DLDQLLQNNDQALLLALDQVTDPHNLGACIRTAAAMGIAAVIVPRDRSASLTPTARKVAA 145

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGM-QILATHLSDNAVDFREIDYTRPTCILMGQEKTG 124
           G    V+      +   +AH+K     +++ T L + A+  ++ D++    I+MG E TG
Sbjct: 146 GGAEKVKFIQVTNLARTLAHIKAHFFVKVVGTMLDEKALPIQKYDFSGNVAIVMGAEDTG 205

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +     +  DQ + IPM G +QSLNVSVA+ + LYEA RQR
Sbjct: 206 LRPITQSQCDQTVYIPMSGNLQSLNVSVAAGMALYEACRQR 246


>UniRef50_B0K3L2 tRNA/rRNA methyltransferase (SpoU) n=11 Tax=Thermoanaerobacterales
           RepID=B0K3L2_THEPX
          Length = 254

 Score =  206 bits (525), Expect = 5e-52,   Method: Composition-based stats.
 Identities = 47/173 (27%), Positives = 80/173 (46%), Gaps = 13/173 (7%)

Query: 1   MNPTRYARICEMLAR------RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG 54
           + P     I ++         +   + +  + +  P N+  IIRTADA G   +  +   
Sbjct: 82  VTPQMVMAIIKIPKYEEDTYIKDKGIYIIADNIQDPGNLGTIIRTADAFGASAIFTINNC 141

Query: 55  SRMRTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR 112
             +       A+ GS   + V    T    +  LK +G+++ ATHL    +   E + + 
Sbjct: 142 VDVFNPKVLRASMGSIFHIPVI--VTASQILLKLKQRGIKVFATHLKARKL-VHECNISD 198

Query: 113 PTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
               ++G E  G++   + L D  + IPM G  +SLNVS+A+ + LYE+QRQR
Sbjct: 199 KVAFVLGNEAKGVS--VVDLVDDFVKIPMTGEAESLNVSIAAGIFLYESQRQR 249


>UniRef50_C0GIN0 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Dethiobacter
           alkaliphilus AHT 1 RepID=C0GIN0_9FIRM
          Length = 245

 Score =  206 bits (525), Expect = 5e-52,   Method: Composition-based stats.
 Identities = 48/168 (28%), Positives = 79/168 (47%), Gaps = 5/168 (2%)

Query: 3   PTRYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MR 58
           P RY    ++LA+   +P   V ++ +  PHN+ A+IRTA A G   +      +     
Sbjct: 77  PFRYTPFADILAKAGDKPPFLVLLDHIQDPHNLGALIRTAYAAGCDGIIIPERRAAQMTP 136

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
                AAG+  ++ V     +   +   K  G+ +    +   +V +   DY   T +++
Sbjct: 137 AAVRTAAGAAEYLPVAKVVNLARCLDECKDAGLWVYGADMDGESV-YTTGDYQGGTVLVI 195

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           G E  G+ +      D  + +PM G V SLN SVA AL++YE  RQR+
Sbjct: 196 GSEGEGLGRLVKEKCDHLVQLPMQGKVASLNASVAGALLMYEVYRQRE 243


>UniRef50_Q7P601 23S rRNA methyltransferase n=10 Tax=Fusobacterium
           RepID=Q7P601_FUSNV
          Length = 234

 Score =  205 bits (524), Expect = 6e-52,   Method: Composition-based stats.
 Identities = 40/162 (24%), Positives = 76/162 (46%), Gaps = 3/162 (1%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMAS 62
            +    E LA +   L + ++++  P N  AIIR+A+   V  +      S     T+  
Sbjct: 74  DFDEAYEELAEKDKSLVLILDEIQDPRNFGAIIRSAEVFKVDLIIIPERNSVRINETVVK 133

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
            + G+  +V +     + D +  LK     +      + ++++ E +Y+    +++G E 
Sbjct: 134 TSTGAIEYVNISKVTNLSDTINKLKKLDYWVYGAA-GEASINYNEENYSNKIILVLGNEG 192

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           +GI ++     D+ I IPM G + SLNVSVAS ++L     +
Sbjct: 193 SGIRKKVREHCDKLIKIPMYGQINSLNVSVASGILLSRIVNR 234


>UniRef50_A5IXH9 tRNA/rRNA methyltransferase n=1 Tax=Mycoplasma agalactiae PG2
           RepID=A5IXH9_MYCAP
          Length = 233

 Score =  205 bits (524), Expect = 7e-52,   Method: Composition-based stats.
 Identities = 47/166 (28%), Positives = 86/166 (51%), Gaps = 3/166 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS--RMR 58
           +    Y  I +++ +  P   + ++ +H PHN  AIIRTA+A G+  +      S     
Sbjct: 67  LKDFNYYEI-DVIKKDNPKTVLILDHIHDPHNFGAIIRTANAAGIKHIIIPKDRSTDVTS 125

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
           T+   ++G    V++     I  ++  LK  G  I ++ L +NAV + ++ Y     +++
Sbjct: 126 TVLKVSSGGFVGVKIIKVSNIASSIEKLKKWGFWIYSSLLDENAVPYNKVQYAGNCALVV 185

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           G E+ GI++  +   D  + IP  G VQS+NVSVA+ ++L+E   +
Sbjct: 186 GNEEKGISKPVVNATDVKVYIPQFGTVQSMNVSVATGILLFELVNR 231


>UniRef50_A4J4Z3 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Desulfotomaculum
           reducens MI-1 RepID=A4J4Z3_DESRM
          Length = 267

 Score =  205 bits (524), Expect = 7e-52,   Method: Composition-based stats.
 Identities = 46/166 (27%), Positives = 76/166 (45%), Gaps = 3/166 (1%)

Query: 4   TRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA-- 61
                + +++   Q  L V ++ V  P N+  IIR+ADA G   V  +     +      
Sbjct: 101 QPDYTLEDIIRPDQKPLVVIVDGVQDPGNLGTIIRSADAAGASGVILLKGTVDIYNPKTL 160

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
            A  GS   + V     + +A+ +L   G+ +L    +   +   + +   P  I++  E
Sbjct: 161 RATMGSLFHLPVIQVSDVNEALEYLASIGVTLLVGEPAGG-IPVFKANLQTPVGIIVANE 219

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
             G  +E      Q I IPM G  +SLNV++A+++ILYEA RQR  
Sbjct: 220 GAGPREEIFRYNHQKITIPMPGCAESLNVAIATSIILYEAIRQRHK 265


>UniRef50_C4G1K9 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
           49176 RepID=C4G1K9_ABIDE
          Length = 279

 Score =  205 bits (524), Expect = 8e-52,   Method: Composition-based stats.
 Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 17/176 (9%)

Query: 2   NPTRYARICEMLARR--QPDLT------------VCMEQVHKPHNVSAIIRTADAVGVHE 47
            P     + EM   R                   + +E    P N+  I+RTA+A GV  
Sbjct: 105 TPQGILAVAEMPDYRLLDKGFLEQAYTKNGKIKLLVLEDTADPGNLGTIMRTAEAAGVTG 164

Query: 48  VHAVWPGSRMRT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDF 105
           V        +    +  +  GS   +       + + +  LK  G+   ATHL      +
Sbjct: 165 VIMGKGTVDIFNPKVVRSTMGSIFRLPFTYVEDLKETIKELKKSGISFYATHLKGE-KSY 223

Query: 106 REIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEA 161
           ++I Y+  + I++G E  G++ E   LAD  ++IPM G V+SLN +VA+AL++YE 
Sbjct: 224 KDIKYSGRSAIIVGNEARGLSDEVADLADTYVLIPMQGKVESLNAAVAAALMMYEV 279


>UniRef50_D2RLA3 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Acidaminococcus
           RepID=D2RLA3_ACIFE
          Length = 260

 Score =  205 bits (524), Expect = 8e-52,   Method: Composition-based stats.
 Identities = 47/169 (27%), Positives = 83/169 (49%), Gaps = 9/169 (5%)

Query: 3   PTRYARICEMLAR------RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           P   A + E+          +  + + ++++  P N+  +IRTADA+G   V  +   + 
Sbjct: 89  PQSVAALVELRREELAAFAPERGMVLVLDRIRDPGNLGTLIRTADALGAAGVVLLENTAD 148

Query: 57  MRT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
           +    +  +  GS   + V T    G+     +  G  + AT L + A D   + +   T
Sbjct: 149 LYNPKVVRSTMGSLFHLPVFTGVKTGELEEWCRQHGYALWATAL-EGAEDMTRLTWPEKT 207

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
            +++G E  G++ E LA ADQ + IPM G  +SLNV+VA  ++++EA R
Sbjct: 208 ALVLGSEAEGVSPEILAAADQKVKIPMAGHAESLNVAVAGGIVMFEAAR 256


>UniRef50_B1X411 tRNA/rRNA methyltransferase (SpoU):RNA methyltransferase TrmH n=1
           Tax=Paulinella chromatophora RepID=B1X411_PAUCH
          Length = 526

 Score =  205 bits (523), Expect = 8e-52,   Method: Composition-based stats.
 Identities = 49/158 (31%), Positives = 79/158 (50%), Gaps = 3/158 (1%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAG 66
           I +     +  L + +E +  PHN+ AI+R+A+A+G H +      +     ++A  AAG
Sbjct: 274 IEDCCHLGENPLLMAVEGLTDPHNLGAIVRSAEALGAHGLILPQRRNAGLTGSVAKVAAG 333

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           +   + V     +  ++  LK +G +I+    ++  V   E D   P  I+ G E  G++
Sbjct: 334 ALEHLPVARVVNLNRSLDILKDKGYRIVGLA-TEGDVSLTEADLNGPLVIVTGSEGNGLS 392

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
                  DQ I IP+ G   SLN SVASAL+LYE  R+
Sbjct: 393 LLTRRYCDQLIRIPLRGATPSLNASVASALMLYEVARR 430


>UniRef50_D1U4M7 tRNA guanosine-2'-O-methyltransferase n=1 Tax=Desulfovibrio
           aespoeensis Aspo-2 RepID=D1U4M7_9DELT
          Length = 226

 Score =  205 bits (522), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 76/197 (38%), Positives = 110/197 (55%), Gaps = 9/197 (4%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           ++  R  RI ++LARRQ DLT+ M+ +  PHNVSA++R+ DA GV +VH  +  S+   +
Sbjct: 25  ISDKRKQRIDQVLARRQKDLTLVMDNIWDPHNVSAVLRSCDAFGVSDVHLYYTTSQWPDL 84

Query: 61  ASAAAG-SNSWVQVKTHRTIGDAVAHL------KGQGMQILATHLSDNAVDFREIDYTRP 113
              ++G +  W+++  H      V +L         G QIL T  S  A    + D+T P
Sbjct: 85  GKKSSGSAMKWIRLIRHVDAATMVGNLVGGGGSAHDGGQILRTGFSATARPVMDFDFTIP 144

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLR 173
           T I++  E  G + E  AL   ++ IPM GMVQSLNVSVA+A+ILYEA  QR+ AG+Y  
Sbjct: 145 TAIILSNEHRGTSPELAALVPDEVYIPMQGMVQSLNVSVAAAIILYEAFTQRKRAGLY-- 202

Query: 174 ENSMLPEAEQQRLLFEG 190
           +     + E   L  E 
Sbjct: 203 DAPSFSDEELAALRAEW 219


>UniRef50_Q9LXE4 rRNA methylase-like protein n=11 Tax=Magnoliophyta
           RepID=Q9LXE4_ARATH
          Length = 350

 Score =  205 bits (522), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 62/196 (31%), Positives = 99/196 (50%), Gaps = 5/196 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW-PGSRMRT 59
           M   R  R   ++  R   + + +E +    N+SA  R+ADA+G+  VH V    S+   
Sbjct: 136 MMEERTDRFRRVVENRSYSVCLVVEGLSDFGNISAAFRSADALGIQSVHVVSCDSSKRYN 195

Query: 60  MAS-AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
                + G+  W+ ++   T  +    LK +G +I  THL  + V   ++D++ PT I++
Sbjct: 196 GNRHVSMGAEKWLDIEFWDTPKECFKVLKSRGYRIATTHLGMDTVSIYDMDWSCPTAIVV 255

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSML 178
           G E  GI+ EAL L+D    IPM GMV S NVSVA+ ++++ A   R      L  +  L
Sbjct: 256 GNEGRGISDEALELSDLRCSIPMNGMVDSFNVSVAAGILMHHAVSDRTT---RLGSHGDL 312

Query: 179 PEAEQQRLLFEGGYPV 194
            EAE++ L+ E     
Sbjct: 313 SEAEKEILMAEFSLRH 328


>UniRef50_A3HSD9 SpoU protein (SpoU) n=1 Tax=Algoriphagus sp. PR1 RepID=A3HSD9_9SPHI
          Length = 234

 Score =  204 bits (521), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 55/213 (25%), Positives = 94/213 (44%), Gaps = 11/213 (5%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           +   +   + ++LA+R    TV +E ++KPHN SA++RT D  G+ +VH +      +  
Sbjct: 21  ITAHKMQVMEKVLAQRTRHFTVVLENIYKPHNASAVLRTCDCFGIQDVHIIEKTREYKVN 80

Query: 61  ASAAAGSNSWVQVKTH------RTIG-DAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
                G++ W+ +  +           +  + LK  G +I  T         +++D    
Sbjct: 81  PFVTRGASQWLTLHKYFQPEEPENAVINCFSSLKSNGFKIYGTSPDPQTRPIQDLDPNEK 140

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLR 173
             ++ G E  GI+ E    AD  + IPM G  +S N+SVA++L L       Q A  Y+ 
Sbjct: 141 IALVFGNEHEGISNEVKNAADGLVHIPMRGFTESFNISVAASLFLQNLV---QKASDYVI 197

Query: 174 ENSMLPEAEQQRLLFEGGYPVLAKVAKRKGLPY 206
            +  L E E+Q L     Y  + K +      Y
Sbjct: 198 PDYNLTEVEKQELRLTW-YRSIVKNSDIHEKKY 229


>UniRef50_B8FEV3 RNA methyltransferase, TrmH family, group 3 n=1
           Tax=Desulfatibacillum alkenivorans AK-01
           RepID=B8FEV3_DESAA
          Length = 249

 Score =  204 bits (520), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 47/170 (27%), Positives = 77/170 (45%), Gaps = 3/170 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--R 58
             P     + +     QP   + M++++ P N  A++RTA   GV+ V      S     
Sbjct: 76  FKPIALELLVKKAGGEQPLFFLLMDEINDPQNCGALMRTALCAGVNGVIMPDKRSSPLSP 135

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
            ++ A+AG+   + V     +  ++ +LK QG+         +     E D T P  +++
Sbjct: 136 AVSKASAGALEHMPVARVVNLVRSMQYLKDQGVWFFGLDARASGT-VWEADLTGPAAVVV 194

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           G E  G+        DQ + IP  G + SLN SVA AL +YE  RQR+ +
Sbjct: 195 GNEGKGLRPLVRKECDQLVSIPQAGPLGSLNASVAGALSMYEVMRQRRMS 244


>UniRef50_D0GJ12 RNA methyltransferase, TrmH family, group 3 n=3
           Tax=Fusobacteriaceae RepID=D0GJ12_9FUSO
          Length = 244

 Score =  204 bits (520), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 39/169 (23%), Positives = 74/169 (43%), Gaps = 7/169 (4%)

Query: 1   MNPTRYA-RICEMLAR---RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++   Y   + E   +   +   + V ++Q+  P N  AIIR+A+  GV  +      + 
Sbjct: 77  VSEFDYYLELTEFFEKVLAKDKSIVVILDQIQDPRNFGAIIRSAECFGVDGIVIQDRNNV 136

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T+  ++ G+   V +     I D +   K  G ++         + + E  Y +  
Sbjct: 137 KVTETVVKSSTGAIEHVDIIKVTNISDTIDKFKKYGYKVYGAEADGENL-YYEESYPKKV 195

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           C+++G E  G+ ++     D+ + I + G   SLNVSVA  +IL E  +
Sbjct: 196 CLVLGSEGNGMRKKVREHCDKTLKIHLKGQTNSLNVSVAGGIILAEMSK 244


>UniRef50_B0TZ81 tRNA/rRNA methyltransferase n=20 Tax=Francisella RepID=B0TZ81_FRAP2
          Length = 248

 Score =  204 bits (520), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 44/160 (27%), Positives = 72/160 (45%), Gaps = 3/160 (1%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAA 65
            I  ++ + +    + ++ V  PHN  A IR+A + G+  +      S     T+   A 
Sbjct: 86  DIENLIPQDKNAFILILDNVQDPHNFGACIRSAHSAGIDFIIIPKDNSAPVNATVKKVAC 145

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G+    ++     +  A+  LK  G+ I+      N      ++      I+ G E +G+
Sbjct: 146 GAAEHTKIVVVTNLARAIEKLKQLGVWIIGLAGEAND-SLYSMNLADSVAIVAGAEGSGM 204

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            Q   A  D    +PM+G V SLNVSVA+ + LYE  RQR
Sbjct: 205 RQRTKASCDFLAKLPMLGEVSSLNVSVATGIALYETVRQR 244


>UniRef50_A8ZSH6 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Desulfococcus
           oleovorans Hxd3 RepID=A8ZSH6_DESOH
          Length = 256

 Score =  203 bits (518), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 48/178 (26%), Positives = 77/178 (43%), Gaps = 6/178 (3%)

Query: 1   MNPTRYARICEMLAR---RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM 57
           ++   +  + ++LA          +  + +  PHN+ A+ RTA   GVH +      +  
Sbjct: 80  VSVYPFVPLADLLAAVPSTDTPFILVADGLTDPHNLGALARTALCAGVHGLIIPKDNAAS 139

Query: 58  RTM--ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
            T     A+AG+  ++ V     I   +  LK  G+ I             + D T P  
Sbjct: 140 PTPAAVKASAGALEFLPVARETNIARVLDALKDAGLWIAGLDGRGE-QTIYDSDLTGPLA 198

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLR 173
           +++G E  GI +      D  + IP   MV SLN SVA A+ +YEA RQR+   +  R
Sbjct: 199 LVVGDEGRGIRRLVGQKCDFILSIPQTDMVHSLNASVAGAVAMYEAFRQRRAKAVIGR 256


>UniRef50_B2S257 Possible rRNA methylase n=3 Tax=Treponema RepID=B2S257_TREPS
          Length = 292

 Score =  203 bits (518), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 50/171 (29%), Positives = 80/171 (46%), Gaps = 4/171 (2%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAG 66
           +   LA     L + ++ +  PHNV AI+R+AD   V  V            T+   +AG
Sbjct: 121 LLHALATHTHALVLVLDAITDPHNVGAIVRSADQFSVDAVLLPHHHGAGGTETITRVSAG 180

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           + +WV +   R +      LK  G  +    ++  A+  R   +   T +++G E  G++
Sbjct: 181 AVAWVPLVRVRNLVRTAGILKRSGFWLYGADVAGEAIGART--FPPKTALVLGNEGHGVS 238

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSM 177
                  D  I IP  G V SLNVSVA+ ++LYE +R +Q+     R+N M
Sbjct: 239 PLLRTHCDALISIPTQGNVDSLNVSVAAGILLYEIRRSQQSPYSVQRQNEM 289


>UniRef50_A6L4B5 tRNA/rRNA methyltransferase n=16 Tax=Bacteroidetes
           RepID=A6L4B5_BACV8
          Length = 255

 Score =  203 bits (518), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 48/168 (28%), Positives = 83/168 (49%), Gaps = 4/168 (2%)

Query: 1   MNPTRYARICEML-ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT 59
           +   +   +   L    +  L V ++ +    N  AI RT +  G   +      S    
Sbjct: 78  VTYQKTEDLVPFLFEEGKTPLFVMLDGITDVRNFGAIARTCECAGADAIIIPSKNSVSVN 137

Query: 60  M--ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
                 +AG+   + V   + + + + +LK  G +I+A        D+ + +Y  P CI+
Sbjct: 138 ADAMKTSAGALHTLPVCREQNLTNTIKYLKDCGFKIVAAT-EKGDYDYTKANYKDPVCII 196

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           MG E TG+  E L+L D+ I IP++G ++SLNVSVA+ +++YEA +QR
Sbjct: 197 MGAEDTGVPYEHLSLCDEWIKIPLMGKIESLNVSVAAGILIYEAVKQR 244


>UniRef50_Q87D65 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=49 Tax=cellular
           organisms RepID=RLMB_XYLFT
          Length = 249

 Score =  203 bits (518), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 3/154 (1%)

Query: 14  ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSNSWV 71
           A     L + ++ V  PHN+ A +R+A A GV  V      S     T+   ++G+   +
Sbjct: 94  AAGGQALLLVLDGVQDPHNLGACLRSAAAAGVTAVIIPKDKSVGINATVRKTSSGAADRL 153

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            V     +  ++  L+ Q + I      +       +D      +++G E  G+ +    
Sbjct: 154 PVIAVVNLARSLRELQKQDVWIYGLA-GEVETSLYALDLRGNVALVLGGEADGLRRLTRE 212

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             D    IPM G V+SLNVSVA+ + L+EA RQR
Sbjct: 213 HCDVLARIPMPGEVESLNVSVAAGVTLFEAVRQR 246


>UniRef50_B4WGA5 RNA methyltransferase, TrmH family, group 3, putative n=1
           Tax=Synechococcus sp. PCC 7335 RepID=B4WGA5_9SYNE
          Length = 365

 Score =  203 bits (518), Expect = 4e-51,   Method: Composition-based stats.
 Identities = 43/170 (25%), Positives = 80/170 (47%), Gaps = 7/170 (4%)

Query: 1   MNPTRYARIC----EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++   Y  +     +   + +  + V  + +  PHN+ AIIR+A+A+G   +      + 
Sbjct: 168 VSAYEYVDLEVLVQQAKNKARRPVIVAADGITDPHNLGAIIRSAEAIGAQGIVIPQRRAV 227

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
               T+A  +AG+   + +     +G A+ +LK     I     ++ A      D++ P 
Sbjct: 228 GVTSTVAKVSAGALENIPIARVINLGRALEYLKSNSFWIYGLT-AEAAQSIHTTDFSAPV 286

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            +++G E +G++     L DQ + I + G   SLN SVA+ + LYE  RQ
Sbjct: 287 VLVVGAEGSGLSLSVQNLCDQLVSIELSGKTPSLNASVATGMALYEIYRQ 336


>UniRef50_B1GZS4 23S rRNA (Guanosine-2'-O-)-methyltransferase n=1 Tax=uncultured
           Termite group 1 bacterium phylotype Rs-D17
           RepID=B1GZS4_UNCTG
          Length = 255

 Score =  203 bits (518), Expect = 4e-51,   Method: Composition-based stats.
 Identities = 39/167 (23%), Positives = 75/167 (44%), Gaps = 5/167 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR-- 58
           +   +Y  + +++  +   L + +E +  P N+  IIR+ADA G   V      + +   
Sbjct: 88  IVEKKYYAVEDII--KNSGLFILLENIQDPGNLGTIIRSADAFGAKAVFVSKGSADIYSD 145

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
               A  GS   + +     I + +  +K + + + A  L        +I +   +  ++
Sbjct: 146 KTIRATMGSIFHLPIIDSINIKNTLNLMKNKKISVFAASLKGE-KYLNDIKFPNKSAFVI 204

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           G E  G+  E    AD  + I M G  +SLN + A+++I+YEA + R
Sbjct: 205 GNEANGLRSETENSADTLVKIYMPGNTESLNAATAASIIMYEAAKNR 251


>UniRef50_C7G6D1 RNA methyltransferase, TrmH family n=5 Tax=Clostridiales
           RepID=C7G6D1_9FIRM
          Length = 281

 Score =  203 bits (517), Expect = 4e-51,   Method: Composition-based stats.
 Identities = 46/162 (28%), Positives = 81/162 (50%), Gaps = 4/162 (2%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAA 65
            + E++   Q  L + +E +  P N+  ++RT +  G+  V        +       +  
Sbjct: 122 ALEELIKGEQTHL-LILESIQDPGNLGTMVRTGEGAGITGVIMNQTTVDLFNPKTIRSTM 180

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           GS   V     + +   ++ LK Q + + A HL    + + E DY + T  L+G E  G+
Sbjct: 181 GSIYRVPFFITKDLAGTISSLKEQQVNVYAAHL-KGTLSYDEPDYKKKTAFLIGNEGNGL 239

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           + E   LAD  I IPM G V+SLN +++++L++YE  RQR++
Sbjct: 240 SDEIADLADTYIKIPMQGQVESLNAAISASLLMYETGRQRRH 281


>UniRef50_B5YID5 RNA methyltransferase, TrmH family, group 3 n=1
           Tax=Thermodesulfovibrio yellowstonii DSM 11347
           RepID=B5YID5_THEYD
          Length = 248

 Score =  203 bits (517), Expect = 4e-51,   Method: Composition-based stats.
 Identities = 59/172 (34%), Positives = 87/172 (50%), Gaps = 7/172 (4%)

Query: 1   MNPTRYARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P +   + E L     + +P   + ++ V  P N  +I R ADA GVH +      S 
Sbjct: 76  IKPKKTITLDEALKISFKKNEPAFFLILDLVEDPQNFGSICRIADAAGVHAIIYQKKRSV 135

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
             + ++  A+AG+   V +     I  A+  LK   + I         V F E D+T+P 
Sbjct: 136 GIVPSVWKASAGAVWHVNLVEINNIKYAIKTLKEHNITIYGAEAQAKDV-FWESDFTQPL 194

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
            +++G E  GI Q  +AL D+ I IPM G + SLNVSVASALI +E  RQR+
Sbjct: 195 GLIVGSEGKGIRQTVIALCDKVIKIPMRGTINSLNVSVASALITFEVLRQRK 246


>UniRef50_B1C951 Putative uncharacterized protein n=1 Tax=Anaerofustis
           stercorihominis DSM 17244 RepID=B1C951_9FIRM
          Length = 242

 Score =  203 bits (517), Expect = 5e-51,   Method: Composition-based stats.
 Identities = 41/159 (25%), Positives = 74/159 (46%), Gaps = 4/159 (2%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAAG 66
           I +M  +    L V ++ +  PHN  AIIR+A   G   V      S      M  ++AG
Sbjct: 86  IEKMNEKVTKPLVVILDNITDPHNAGAIIRSAYCAGADGVIMQTRRSASIGEGMYKSSAG 145

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           +   + +     I   +  LK +G+ ++   ++    ++ ++DY  P  +++G E  G+ 
Sbjct: 146 AIEHIDLCEVSNIAQTIDTLKKEGLFVVGLDMNGE--NYYDMDYDMPLALVVGAEGKGLG 203

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +      D    IP+     SLN SVA+ ++L+EA + R
Sbjct: 204 RLIKEKCDFISSIPLKNDFDSLNASVAAGIVLFEAVKTR 242


>UniRef50_C6X1H8 rRNA methylase n=4 Tax=Bacteroidetes RepID=C6X1H8_FLAB3
          Length = 265

 Score =  203 bits (517), Expect = 5e-51,   Method: Composition-based stats.
 Identities = 51/173 (29%), Positives = 90/173 (52%), Gaps = 7/173 (4%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++   +  I ++L       +    + ++++    N  AI RTA+ VGVH +     G+ 
Sbjct: 91  ISDVPFESIQDVLPQLFEEGKTPFLLILDRLTDVRNFGAICRTAECVGVHAIILPEKGAA 150

Query: 57  MRT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
                    +AG+   +++   + +  AV  L+  G+Q+ +           ++D+T+P 
Sbjct: 151 PINSDAIKTSAGAIYNLRICKEKNLAHAVDFLQQSGLQVFSAS-EKAQKLIYDVDFTQPC 209

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
            I+MG E+TGI++E L  +D+ I +P+ G  QSLNVSVA   ILYEA RQ+ +
Sbjct: 210 AIVMGNEETGISKEVLHHSDEKIKLPIEGKTQSLNVSVACGAILYEAVRQKLS 262


>UniRef50_C4Z380 RNA methyltransferase, TrmH family n=1 Tax=Eubacterium eligens ATCC
           27750 RepID=C4Z380_EUBE2
          Length = 279

 Score =  202 bits (516), Expect = 5e-51,   Method: Composition-based stats.
 Identities = 49/172 (28%), Positives = 72/172 (41%), Gaps = 9/172 (5%)

Query: 2   NPTRYARICEMLARR------QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS 55
            P     +  M             L + +E +  P N+  I+R  +  GV  V       
Sbjct: 107 TPQGIMAVVRMKDSSISDMLTDNPLLILVENLQDPGNLGTILRMGEGAGVTGVIMSSNTV 166

Query: 56  RMRTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
            +       +  GS   V     +   DAV+  K  G+++ A HL        E DY   
Sbjct: 167 DIYNPKTIRSTMGSIFRVPFVYVQDFSDAVSQCKNAGIKVYAAHLDGKNTYLGE-DYREG 225

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           T  L+G E  G+T++    AD  I IPM G V+SLN ++A  ++ YEA RQR
Sbjct: 226 TAFLIGNEGNGLTEDITKQADTLIRIPMQGEVESLNAAIACTILTYEAVRQR 277


>UniRef50_C0Z9E4 Putative RNA methyltransferase n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0Z9E4_BREBN
          Length = 271

 Score =  202 bits (516), Expect = 6e-51,   Method: Composition-based stats.
 Identities = 46/160 (28%), Positives = 86/160 (53%), Gaps = 3/160 (1%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAG 66
           + +    +   L + ++++  P N+  I+RTA+A  +  V        +    +  A  G
Sbjct: 113 VDQKREEQGSLLLLFLDEIQDPGNLGTILRTAEAAAIDGVVLGSGSVDIYNGKVVRATMG 172

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           +   + V T +++ D     K +G ++L + L  N+V + E DY   T +++G E  G++
Sbjct: 173 ALFRIPVFT-QSLVDTADEWKAKGGRVLISSLEQNSVSYDEADYAGLTALVIGNEGRGVS 231

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           +E  A ADQ + IP+ G  +SLN +VA+ + +YEAQR+R+
Sbjct: 232 KEMFAKADQFVHIPLYGGAESLNAAVAAGIFVYEAQRKRR 271


>UniRef50_Q1IWR8 RNA methyltransferase TrmH, group 3 n=6 Tax=Deinococci
           RepID=Q1IWR8_DEIGD
          Length = 246

 Score =  202 bits (515), Expect = 9e-51,   Method: Composition-based stats.
 Identities = 49/171 (28%), Positives = 80/171 (46%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARICEMLARRQPD----LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           +    +A + ++L R +      L V ++ +  P N  AIIR+A+ +G H V      S 
Sbjct: 66  VEDLAWATVDDILDRAEARGEDLLIVLLDGITDPRNFGAIIRSAEVLGAHGVVVEERRSA 125

Query: 57  M--RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
                +   AAG+ S++ V   + +   +  LK  G+ I      + A D    D +   
Sbjct: 126 PLSPVVVKTAAGATSYLPVAQTKNLPRLIDALKEDGVWIYGAA-GEAAQDIGRTDLSGKV 184

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            +++G E  G+ +      D  + IP  G VQSLN SVA+ ++LYEA R R
Sbjct: 185 ALVIGAEGEGLRRLVREKCDALVRIPTRGQVQSLNASVAAGILLYEAARAR 235


>UniRef50_Q3AXD9 RNA methyltransferase TrmH, group 3 n=19 Tax=Bacteria
           RepID=Q3AXD9_SYNS9
          Length = 652

 Score =  202 bits (514), Expect = 9e-51,   Method: Composition-based stats.
 Identities = 43/159 (27%), Positives = 77/159 (48%), Gaps = 3/159 (1%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAG 66
           I       +P L + ++ +  PHN+ A++R+A+A+G H +      S     + A  AAG
Sbjct: 373 IEGCSELGEPPLLLALDGITDPHNLGAVVRSAEAMGAHGLVLPQRRSAGLTGSAAKVAAG 432

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
           +   + V     +  ++  LK  G +++      + V   ++D   P  ++ G E  G++
Sbjct: 433 AMEHLPVARVVNLNRSLEKLKDSGYRVIGLAAEGD-VTLMDVDLEGPLVLVTGSEDQGLS 491

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
                  DQ + IP+ G+  SLN SVA+AL +YE  R+ 
Sbjct: 492 LLTRRHCDQLVRIPLRGITPSLNASVATALCVYEVARRN 530


>UniRef50_Q31LC0 RNA methyltransferase TrmH, group 3 n=22 Tax=Bacteria
           RepID=Q31LC0_SYNE7
          Length = 519

 Score =  201 bits (513), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 49/180 (27%), Positives = 80/180 (44%), Gaps = 7/180 (3%)

Query: 1   MNPTRYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           + P  Y  + +++A+ +      + V  + +  PHN+ AIIRTA+A+G H +      + 
Sbjct: 313 VAPYPYQELSDLIAQAKAATTDPVIVVADGITDPHNLGAIIRTAEALGAHGLVIPQRRAV 372

Query: 57  MRTMASAAAGS--NSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
             T A A   +       V     +  A+  LK  G  I      +      E  ++ P 
Sbjct: 373 GVTAAVAKVAAGALESFPVARVVNLNRALEELKDAGFWIYGAA-GEAKQSIHETSFSGPV 431

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRE 174
            +++G E  G++       D  I IP+ G   SLN SVA+ ++LYE  RQRQ    +L  
Sbjct: 432 VLVVGSEDEGLSLLTRERCDHLISIPLRGKTNSLNASVAAGMVLYEVSRQRQQLTHHLEG 491


>UniRef50_D1CD69 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Thermobaculum
           terrenum ATCC BAA-798 RepID=D1CD69_THET1
          Length = 264

 Score =  201 bits (513), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 4/166 (2%)

Query: 2   NPTRYARICEMLARRQ--PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--M 57
           +   Y+ I ++LA  +      + ++ +  P N   ++RTA+  G+  V      S    
Sbjct: 94  SEFSYSSIEDLLASGELRGKDILMLDSLQDPQNFGTLLRTAEVFGIGAVIIPEHRSVEVT 153

Query: 58  RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
             + +A++G+   + +     +    + LK  G  +L     +++    ++D   P C++
Sbjct: 154 PAVVNASSGATEHLNISKVTNLARTASKLKEYGYWVLGLEYDESSSVIWDVDLRIPICLV 213

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           +G E +GI +      D  + IP  G + SLN +VA ++ LYE  +
Sbjct: 214 VGSEGSGIRELVRKRCDLLVKIPQAGRIGSLNAAVAGSIALYEIYK 259


>UniRef50_C8N9X3 23S rRNA (Guanosine-2'-O-)-methyltransferase RlmB n=1
           Tax=Cardiobacterium hominis ATCC 15826
           RepID=C8N9X3_9GAMM
          Length = 243

 Score =  201 bits (513), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 43/160 (26%), Positives = 75/160 (46%), Gaps = 3/160 (1%)

Query: 11  EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSN 68
           + +A  +  L + ++ +  PHN+ A +R+A A GVH V      +      +   A G+ 
Sbjct: 85  DAIAGVEKPLLLVLDSIQDPHNLGACLRSAAAAGVHAVLIPNSRAADVTPVVEKVACGAT 144

Query: 69  SWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQE 128
             + +     +   V  ++ QG+ ++       A      D T P  +++G E  GI   
Sbjct: 145 EILPLFRVSNLRREVERMQRQGIWVVGGA-GGAAQSLYATDLTVPLAVIVGNEGEGIRHG 203

Query: 129 ALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
                D  + IPM   ++SLNVSVA  ++L+EA+RQR  +
Sbjct: 204 LREQCDFLVQIPMAEGMESLNVSVACGVMLFEARRQRLFS 243


>UniRef50_C9KPX8 RNA methyltransferase, TrmH family n=1 Tax=Mitsuokella multacida
           DSM 20544 RepID=C9KPX8_9FIRM
          Length = 271

 Score =  201 bits (513), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 58/168 (34%), Positives = 83/168 (49%), Gaps = 5/168 (2%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR--TM 60
           P     + +  AR+   L V ++ V  P N   IIRTADAVG   V        +     
Sbjct: 107 PQMAEHLQQAAARK--PLLVVLDGVQDPGNAGTIIRTADAVGADGVILTKGSVDVFSDKT 164

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
             A  GS   + V T  +  +     +  G Q+LAT L + A     +D+ + + I  G 
Sbjct: 165 VRATMGSLFHLPVVTDVSAEEVATFAQAAGCQLLATALDEQAKPHFAVDFGKGSLIAFGN 224

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           E  G+++E LA A + + IPM G  +SLNV V+SA++LYEA RQR  A
Sbjct: 225 EGGGVSEELLAAA-EKVYIPMYGEAESLNVGVSSAVVLYEAVRQRHFA 271


>UniRef50_C2D9C1 Possible tRNA/rRNA methyltransferase n=1 Tax=Atopobium vaginae DSM
           15829 RepID=C2D9C1_9ACTN
          Length = 372

 Score =  200 bits (510), Expect = 3e-50,   Method: Composition-based stats.
 Identities = 38/157 (24%), Positives = 68/157 (43%), Gaps = 3/157 (1%)

Query: 14  ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM--ASAAAGSNSWV 71
           A +Q  L V ++ V    N  AI+R+A+ VG   V           +     +AG+   +
Sbjct: 216 AHKQASLVVLLDHVVDEGNFGAIVRSAEVVGASCVIIANARCASVGVGAYKTSAGAVLHM 275

Query: 72  QVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALA 131
            +     +  A+  LK  G  ++            +  +T   C++MG E+ GI+     
Sbjct: 276 PIVQVVNLARAIDELKEHGFWVIGASEHAQ-QTVWDAPFTGKVCLIMGSEENGISSLVQK 334

Query: 132 LADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
             D    +P  G ++SLNV+ A+ ++ YE  RQ + +
Sbjct: 335 KCDFICKLPQRGRIESLNVAQAATVMCYEWMRQNKLS 371


>UniRef50_D1VT15 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Peptoniphilus
           lacrimalis 315-B RepID=D1VT15_9FIRM
          Length = 234

 Score =  200 bits (509), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 37/168 (22%), Positives = 73/168 (43%), Gaps = 7/168 (4%)

Query: 1   MNPTRYARICEMLARRQPD---LTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM 57
           ++   Y    E+L   +       + ++++  PHN+ AI R+A       +        +
Sbjct: 69  VSGYEYKDFQELLDENKDKKEFRLLILDKMEDPHNLGAIARSALFFNFDGIIIPKHREAL 128

Query: 58  RT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
               +   + G+   V +     +   +  LK  G  I A  L  +  + +++D++    
Sbjct: 129 VNDTVYKTSQGAVDNVNICQVTNLSQTIEKLKKAGFWIYAALLEGD--NIKDVDFSGKVA 186

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           I++G E  GI+   +  +D  + IP +    SLN SVA+ +I+YE  R
Sbjct: 187 IIIGNEGKGISDNLIKASDFKVKIPNLSEFDSLNASVAAGIIMYEVIR 234


>UniRef50_C0WU39 RNA methyltransferase n=3 Tax=Lactobacillus RepID=C0WU39_LACBU
          Length = 255

 Score =  199 bits (507), Expect = 7e-50,   Method: Composition-based stats.
 Identities = 37/170 (21%), Positives = 82/170 (48%), Gaps = 9/170 (5%)

Query: 2   NPTRYARIC------EMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS 55
            P     +       E +  +     + ++ +  P N+  ++RTADA G++ V      +
Sbjct: 87  TPQGVFAVLTTENYHESIPEKLGGSWLMLDNIQDPGNIGTMVRTADAAGMNGVIFGKGTA 146

Query: 56  RMRT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
            +    +  +  GS   V++ +   +   +A      + +  T L+D A+ + +++ T+ 
Sbjct: 147 DIYNPKVVRSMQGSQFHVRLYS-GDLAVWMAAFNKHNVPVYGTELNDQAISYDDVEPTKQ 205

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
             ++MG E  G++ + L   DQ++ IPM G  +SLNV+VA+ ++++   +
Sbjct: 206 FALVMGNEGNGVSADLLDKTDQNLYIPMNGEAESLNVAVATGILIFHFVK 255


>UniRef50_D1R5P1 Putative uncharacterized protein n=1 Tax=Parachlamydia
           acanthamoebae str. Hall's coccus RepID=D1R5P1_9CHLA
          Length = 277

 Score =  199 bits (507), Expect = 7e-50,   Method: Composition-based stats.
 Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARICEM---LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           + P  +  + ++   L  +     +  E + KP N+  I+R +DAVG+  +      +  
Sbjct: 106 IAPQFHLSLEDLGKQLKNQNNPFLIVAEAIEKPGNLGTILRCSDAVGLDALIVCDACTDI 165

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
               +  A+ G+   V V   +   + +  LK +G+ ILA        +  +ID T P  
Sbjct: 166 HNPNVVRASVGTLFTVPVIESQG-AETLQWLKQKGISILAATPHAK-QELADIDLTGPLA 223

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           I +G E+ G++ + +  AD  + IPM G+  SLNV++A+ ++LYEA RQR+
Sbjct: 224 IAVGTEQLGLSPQWMEQADIQVRIPMYGIADSLNVAMATTILLYEALRQRK 274


>UniRef50_C1TM87 rRNA methylase, putative, group 3 n=1 Tax=Dethiosulfovibrio
           peptidovorans DSM 11002 RepID=C1TM87_9BACT
          Length = 269

 Score =  199 bits (506), Expect = 8e-50,   Method: Composition-based stats.
 Identities = 43/158 (27%), Positives = 74/158 (46%), Gaps = 3/158 (1%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAA 65
            + +   ++ P L + M+ V  PHN  A+IRTA+AVG   V      S     T+   +A
Sbjct: 107 DLSQFSPKKGPSLLLAMDHVKDPHNFGAMIRTAEAVGALGVIYPSRRSVGVTGTVIKTSA 166

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G+   V +     +  ++  LK +G  ++     +   D           +++G E  G+
Sbjct: 167 GAAFRVPLYEVTNLVRSMEILKKEGYWVVGLD-HEEPRDIWSSPLPDKLVLMVGSEGEGL 225

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           ++ +    D    IPM+G   SLN SVA+AL ++E +R
Sbjct: 226 SRLSSERCDDLRRIPMVGKTGSLNASVAAALGMFEWRR 263


>UniRef50_C2FZ75 Possible tRNA/rRNA methyltransferase n=2 Tax=Sphingobacterium
           spiritivorum RepID=C2FZ75_9SPHI
          Length = 259

 Score =  199 bits (506), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 54/172 (31%), Positives = 89/172 (51%), Gaps = 7/172 (4%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++P  Y +I +++     + +  L + ++ V    N+ AI RTA+  GVH +     GS 
Sbjct: 86  ISPITYQKIEDLIPEIYEKGETPLILMLDGVTDVRNLGAIARTAECSGVHAIIVPKKGSA 145

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
                    +AG+   + V  H  +G     L   G+Q++ +           +DYT PT
Sbjct: 146 EINPDAIKTSAGALYKIPVCRHDNLGKVGKFLIDSGIQLVVST-EKTEESIYSVDYTAPT 204

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           CI+MG E  G++ + + ++D    IPM G + SLNVSV++ ++LYEA RQRQ
Sbjct: 205 CIIMGAEDVGVSDDLIRISDHLAKIPMFGEIGSLNVSVSAGVVLYEAIRQRQ 256


>UniRef50_C4L451 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Exiguobacterium sp. AT1b
           RepID=C4L451_EXISA
          Length = 248

 Score =  198 bits (505), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 4/152 (2%)

Query: 15  RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQ 72
            R+    + +++V  P N+  +IRTADA G   V             +  A  GS   V 
Sbjct: 99  ERKMKKVLVLDRVQDPGNLGTMIRTADAAGFDTVLLGKGTVDPFNAKVVRATQGSLFHVN 158

Query: 73  VKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALAL 132
           V +   + + +  LK  G  +  T LS  A  + ++ +     +++G E  G+  + LAL
Sbjct: 159 VTSV-DLLEKLPELKEDGFHVYGTALS-KATSYEQVAFEEKVALVIGNEAQGVHADVLAL 216

Query: 133 ADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            D  + IP++G V+SLN +VA+ +++Y    Q
Sbjct: 217 CDTRVHIPVLGDVESLNAAVAAGILMYRIALQ 248


>UniRef50_C7H9L6 RNA methyltransferase, TrmH family, group 3 n=3 Tax=Ruminococcaceae
           RepID=C7H9L6_9FIRM
          Length = 267

 Score =  198 bits (505), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 48/173 (27%), Positives = 83/173 (47%), Gaps = 11/173 (6%)

Query: 2   NPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW--PGS 55
           +   Y  + ++L     + +P   V  + +  PHN+ A++R+A   G H +        S
Sbjct: 94  SEIEYVTVEDLLNVAREKGEPPFLVLSDGIEDPHNLGAVMRSALLCGAHGIVIPKRGGAS 153

Query: 56  RMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T+  ++AG+   + V     IG+ +  LK QG+ +    +    V  R+ + T P  
Sbjct: 154 VTPTVIKSSAGAAERLPVARVANIGETIRRLKDQGVFVYCADMDG--VPLRKNNLTGPIA 211

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGM---VQSLNVSVASALILYEAQRQR 165
           +++G E +G++Q    L D  + + M      V S NVSVA+ +ILYE Q QR
Sbjct: 212 LVLGSEGSGVSQLVKKLCDGVVRLDMAAQGTGVDSFNVSVAAGIILYEIQSQR 264


>UniRef50_UPI0001C42339 RNA methyltransferase, TrmH family n=1 Tax=Bacillus pseudofirmus
           OF4 RepID=UPI0001C42339
          Length = 281

 Score =  198 bits (505), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 44/164 (26%), Positives = 80/164 (48%), Gaps = 8/164 (4%)

Query: 2   NPTRYARICEMLARRQ----PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM 57
            P   A +C + A           + +++V  P N+  +IRTADA G+  V        +
Sbjct: 116 TPQGIAAVCAIPAPPSMTTLSGQFLLIDRVQDPGNIGTMIRTADAAGMTGVVLGEGSVDL 175

Query: 58  RT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
               +  A+ GS   + V    ++ + V  LK + + +  T L++ +  +  I+      
Sbjct: 176 FNSKVIRASQGSIFHMPVIR-GSLIEWVEKLKEKNIPVFGTSLTEAS-SYTAIEPQPEFA 233

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILY 159
           +++G E  G+  E L  +DQ+I IP+ G  +SLNV+VA+ ++LY
Sbjct: 234 LIVGNEGEGVQSELLEGSDQNIYIPIYGQAESLNVAVATGILLY 277


>UniRef50_D2QM84 RNA methyltransferase, TrmH family, group 3 n=2
           Tax=Flexibacteraceae RepID=D2QM84_9SPHI
          Length = 276

 Score =  198 bits (504), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 50/161 (31%), Positives = 84/161 (52%), Gaps = 5/161 (3%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAG 66
           I ++  R +    + ++++    N  AI RTA+  G+  +     G+          ++G
Sbjct: 109 IADVFERGEVPFFLLLDRITDVRNFGAIARTAECTGIQCIVIPGRGAAAINSDAMKTSSG 168

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFRE--IDYTRPTCILMGQEKTG 124
           + + + V     + + V +L+  G+ ++A     +A D  E   D T P  I+MG E+ G
Sbjct: 169 ALNHISVCREPDLTETVKYLQESGITVVACT-EKSARDLYERTTDLTGPMAIIMGSEEDG 227

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           I+ E L + D  + IP++G V SLNVSVA+ +ILYEA RQR
Sbjct: 228 ISPELLRMVDTHVKIPLLGAVGSLNVSVATGVILYEAVRQR 268


>UniRef50_B3PM16 SpoU class tRNA/rRNA methyltransferase n=1 Tax=Mycoplasma
           arthritidis 158L3-1 RepID=B3PM16_MYCA5
          Length = 229

 Score =  197 bits (503), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 42/162 (25%), Positives = 87/162 (53%), Gaps = 3/162 (1%)

Query: 4   TRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS--RMRTMA 61
            +Y  +  +  + +P+L + ++ +  PHN  AIIR A+  G+  +      +     T+ 
Sbjct: 67  YQYYDLGTIF-KDKPNLVLMLDHIQDPHNFGAIIRNANGFGIKHIIIPKNRACEVTPTVL 125

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
             ++G+ + +++    ++ D +  L+  G  I ++ L D A    +  +  PTC+++G E
Sbjct: 126 KISSGAFTEIKIIRVGSLFDTLKELQKNGFWIYSSTLDDKATKLHKTKFATPTCLIVGNE 185

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           ++G++   +  +D  + I   G VQSLNV+ A+A++LYEA +
Sbjct: 186 ESGVSHTLIKHSDALVYIEQKGTVQSLNVASATAVLLYEATK 227


>UniRef50_A5UYW3 RNA methyltransferase, TrmH family, group 3 n=4 Tax=Chloroflexi
           (class) RepID=A5UYW3_ROSS1
          Length = 252

 Score =  197 bits (503), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 39/172 (22%), Positives = 82/172 (47%), Gaps = 6/172 (3%)

Query: 2   NPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           +   Y  + + L     R +P   + ++ +  P NV  ++RTA+ VGVH V      +  
Sbjct: 76  SDYPYVDLNDCLALAEERGEPAFLLLLDHIQDPQNVGTLLRTAEVVGVHGVVIPGRRAAE 135

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
               + + ++G+   ++V     +   +  ++  G+ ++     + A ++  +D   P  
Sbjct: 136 VTPAVVNTSSGAVEHLRVAVVTNLAATIEQIQHAGVWVVGVEDDERAYEYDRVDLDLPLA 195

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           +++G E  G+ +      D  + +PM G + SLNV+VA +++LY A R R+ 
Sbjct: 196 LVLGAEGPGLARLTRERCDFLVRLPMRGQIASLNVAVAGSIVLYHAWRVREQ 247


>UniRef50_B1I4I6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Candidatus Desulforudis
           audaxviator MP104C RepID=B1I4I6_DESAP
          Length = 272

 Score =  197 bits (503), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 50/167 (29%), Positives = 77/167 (46%), Gaps = 3/167 (1%)

Query: 8   RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAA 65
            +  +L  R   L V ++ +  P N+  IIRTADA  +  V  +          +  A+A
Sbjct: 106 SLDVLLQGRGTPLVVVLDGLQDPGNLGTIIRTADACELQGVITLEGTVDLFHPKVVRASA 165

Query: 66  GSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGI 125
           G+   +           +    G G+Q        +     E D++RPT + MG E  G 
Sbjct: 166 GALFHLPAFGDLPAPAVLEFFTGAGVQKFVADPRGD-YSLYECDFSRPTALFMGNEARGC 224

Query: 126 TQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYL 172
            +   A AD+ + IPM G  +SLNV VA++L +YEA RQR  + + L
Sbjct: 225 GEMLHAAADRVVAIPMPGQAESLNVGVAASLFIYEAVRQRLKSSLSL 271


>UniRef50_B1AIB3 RNA methyltransferase, TrmH family, group 3 n=15 Tax=Ureaplasma
           RepID=B1AIB3_UREP2
          Length = 239

 Score =  197 bits (503), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 41/159 (25%), Positives = 78/159 (49%), Gaps = 3/159 (1%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASA 63
                +++  ++  L + ++++  P N  AIIRTA+  GV  +             +   
Sbjct: 77  LESFLKLIKDKKNALVLILDEIEDPRNFGAIIRTANGFGVDAIIYKKHHQASINDLVIKT 136

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           + G+ +++ +     + + + +L+ +G  + AT L   +  + ++DY   T  ++G E  
Sbjct: 137 SMGAINYIYMIEVNNLSNTIKNLQDEGFWVYATSLL-KSQPYEKVDYANKTVFIVGNENK 195

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
           G++   L  ADQ I I M G VQSLNV VA+ +IL   +
Sbjct: 196 GVSPLILKNADQSIRIDMFGDVQSLNVGVATGIILAHYR 234


>UniRef50_A5N255 Predicted methyltransferase n=28 Tax=Clostridium RepID=A5N255_CLOK5
          Length = 266

 Score =  197 bits (502), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 38/175 (21%), Positives = 84/175 (48%), Gaps = 7/175 (4%)

Query: 2   NPTRYARICEMLA---RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
           NP     + +      + +    +  +++  P N+  IIR+A A G   +        + 
Sbjct: 92  NPQGIIAVVKNKELNIKDEQGFYILADRIQDPGNMGTIIRSAHASGALGIITTKGTVDVY 151

Query: 59  T--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
                 A  GS  ++ +     +   V+ L+  G +++++ L  + ++F ++D      I
Sbjct: 152 NEKTLRATMGSIFYIPIIQDENLEK-VSTLRQMGFKLISSSLDSD-INFYDMDLRGKIII 209

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMY 171
            +G E  G+ Q+   ++D ++ IPM G  +SLN +VA++++++E  RQ+ N+ + 
Sbjct: 210 AIGNEGNGLLQDVKKISDIEVNIPMPGNAESLNAAVAASIMMFEVVRQKLNSHVD 264


>UniRef50_A2U3D3 SpoU rRNA methylase n=2 Tax=Flavobacteriaceae RepID=A2U3D3_9FLAO
          Length = 248

 Score =  197 bits (501), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 44/171 (25%), Positives = 81/171 (47%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARI----CEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++P  +  +     + L   +    + ++Q+    N  AIIRTA+  GV+ +     GS 
Sbjct: 75  ISPIDFYDLETLLDDTLEAEKVPFFLILDQLSDVRNFGAIIRTAECTGVNGIIIQKNGSA 134

Query: 57  MRTM--ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
                    +AG+   + +     I DA+  L+   ++ +A     ++    ++++ +P 
Sbjct: 135 PVNAETIKTSAGAAFKMPICKVDHIKDALFILQASNIKTVAATEKTDS-SIYDVNFNQPI 193

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            I+MG E  G+    L + D    +P+ G ++SLNVSVA  + LYE  RQR
Sbjct: 194 AIIMGSEHRGVNPSVLKMVDYKAKLPLSGNIESLNVSVACGVFLYETVRQR 244


>UniRef50_A8MI79 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Clostridiaceae
           RepID=A8MI79_ALKOO
          Length = 278

 Score =  197 bits (501), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 40/158 (25%), Positives = 80/158 (50%), Gaps = 5/158 (3%)

Query: 8   RICEMLARRQPDLT-VCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAA 64
            + E+ +++  +L  V ++++  P N+  IIRTA++     V                A 
Sbjct: 109 SLEEIKSQKGKELFFVILDRIQDPGNMGTIIRTAESANADAVIITKGSVDPYNSKTLRAT 168

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTG 124
            G+   + +         +  LK   ++++A  L  +   + +IDY     I++G E  G
Sbjct: 169 MGAIFHMPIIQCDD-DRWLDDLKENEVKLIAADLDTDKT-YIDIDYNTSIGIIIGNEANG 226

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
           I++  L+  DQ +IIP++G ++SLN SVA+++++Y+A 
Sbjct: 227 ISEALLSKVDQRVIIPILGKIESLNASVAASILIYKAA 264


>UniRef50_Q6AJ92 Related to tRNA/rRNA methyltransferase n=1 Tax=Desulfotalea
           psychrophila RepID=Q6AJ92_DESPS
          Length = 295

 Score =  197 bits (501), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 50/161 (31%), Positives = 79/161 (49%), Gaps = 2/161 (1%)

Query: 6   YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASA 63
             +  + + R +    +  + +  PHN+ AI+R+A A G   V      S     T A +
Sbjct: 131 LQKFKDAVDRGEKPRIIVCDSLQDPHNLGAIVRSALASGAIGVLLTRERSAPLGGTAAKS 190

Query: 64  AAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKT 123
           +AG+ S + +     +  ++A LK  G  +       +AV   + D   P CI++G E T
Sbjct: 191 SAGAISHMDICQVTNLVKSLAELKKVGAWVFGAIKDADAVSLFDADLNVPACIVVGSEGT 250

Query: 124 GITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           GI        D  + IPM+G + SLN SVA+A+IL+EA RQ
Sbjct: 251 GIRPLVRRECDIQLSIPMVGELDSLNSSVAAAVILFEAMRQ 291


>UniRef50_Q8DNE3 Possible rRNA/tRNA methylase n=69 Tax=Streptococcaceae
           RepID=Q8DNE3_STRR6
          Length = 252

 Score =  197 bits (501), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 47/167 (28%), Positives = 78/167 (46%), Gaps = 7/167 (4%)

Query: 2   NPTRYARICEMLARRQPDL----TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM 57
            P     + +     Q DL     + +E V  P NV  IIRTADA G   V      + +
Sbjct: 87  TPQGIVAVVQKEEVGQADLSQGKFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADI 146

Query: 58  RTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
            ++    +  GS+  + +    +    +   K   + +LAT LS ++VD+RE+       
Sbjct: 147 YSLKTLRSMQGSHFHLPIYRMTSPA-LLDETKKVAIPVLATTLSKDSVDYRELPSIENFV 205

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
           ++MG E  GI+      ADQ + I M G  +SLNV+VA+ ++++   
Sbjct: 206 LVMGNEGQGISPLMAESADQLVHISMKGQAESLNVAVAAGILIFHLS 252


>UniRef50_C4ZGM4 RNA methyltransferase, TrmH family, group 3 n=8 Tax=Clostridiales
           RepID=C4ZGM4_EUBR3
          Length = 263

 Score =  197 bits (501), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 43/167 (25%), Positives = 78/167 (46%), Gaps = 4/167 (2%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--S 62
            +  I E+    + +L + +E +  P N+  ++RT +  GV  +        +       
Sbjct: 98  PHYEIDELFKGDKTEL-LVLESIQDPGNLGTMVRTGEGAGVSGIIMNRTTVDIFNPKTVR 156

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
           +  GS   V       + + + + K +G+ + A HL      +   DYT     ++G E 
Sbjct: 157 STMGSLYRVPFYITDDLPETIEYAKSKGVSLYAAHLKGK-CSYDRPDYTGACGFMIGNEG 215

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
            G++ E   +AD  I IPM G V+SLN ++++ L++YE  RQR+  G
Sbjct: 216 NGLSDEIADMADTYIRIPMEGAVESLNAAISATLLMYECNRQRRLLG 262


>UniRef50_A9S3U1 Predicted protein (Fragment) n=2 Tax=Physcomitrella patens subsp.
           patens RepID=A9S3U1_PHYPA
          Length = 241

 Score =  196 bits (500), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 55/196 (28%), Positives = 98/196 (50%), Gaps = 5/196 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAV--WPGSRMR 58
           +   R  RI E++A R   + + +E +    NVSA+ R+ADA+G   VH +      R +
Sbjct: 34  LGDERKQRIEEVVANRTYSICIAVEGLLDLGNVSAVCRSADALGFQSVHVISNETKKRYK 93

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
                + G+  W+  +      D +  L+ +G +I  TH++ + V   ++D+T PT +  
Sbjct: 94  KNRKVSMGTEKWLDAELWSNTSDCIDTLRQRGYRIAVTHIAPDTVSIYDMDWTIPTAVFF 153

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSML 178
           G E  G ++EA+  +D    IPM GMV+S N+SVA+ +I++ A R R    +    +  +
Sbjct: 154 GNEFMGASEEAIKQSDVRCCIPMAGMVESFNISVAAGIIMHHAARDR---IIRSGVHGDI 210

Query: 179 PEAEQQRLLFEGGYPV 194
              +++ L  E     
Sbjct: 211 SPEDRRILEAEFCLRH 226


>UniRef50_B4U792 RNA methyltransferase, TrmH family, group 3 n=9 Tax=Aquificales
           RepID=B4U792_HYDS0
          Length = 251

 Score =  196 bits (500), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 45/173 (26%), Positives = 82/173 (47%), Gaps = 6/173 (3%)

Query: 1   MNPTRYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
           ++P  Y    E+  +   +    V ++ +  P NV +I RT +  G   +      S   
Sbjct: 77  LSPITYVPEEELFRKTIEEKGFFVVLDHITDPQNVGSIARTVEVFGGIGLLIPKDRSAPI 136

Query: 59  T--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
              +  +++G+   +++    +I  A+   K  G  + A  L     D  ++D+  P CI
Sbjct: 137 NAVVVKSSSGAIFHLKISKTPSISKAIKTFKEMGGWVYA--LEKGGKDITKVDFAYPMCI 194

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
           ++G E  G+++  L  +D  + IPM G V SLNVS A A+ L+E  + ++N G
Sbjct: 195 VLGSEGEGVSKNVLEHSDVRVSIPMKGKVTSLNVSAAGAICLWEVYKNQENTG 247


>UniRef50_B6IRN7 RNA methyltransferase, TrmH family, group 3 n=4 Tax=Proteobacteria
           RepID=B6IRN7_RHOCS
          Length = 251

 Score =  196 bits (500), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 49/169 (28%), Positives = 76/169 (44%), Gaps = 6/169 (3%)

Query: 2   NPTRYARICEML---ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
            P     + ++          L + ++QV  PHNV AI+R+A A G   V      +   
Sbjct: 84  APLPEVAVEDVCIAAESEPQALVIVLDQVTDPHNVGAIMRSAAAFGARAVIVQDRHAPPV 143

Query: 59  T--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
           T  +A  A+G+   V +     +  A+  LK  G   +    S  A    E+D T  T +
Sbjct: 144 TGVLAKTASGAVDAVPLVRVTNLARALDTLKQAGFWTVGLDESG-ARPLHEVDLTGRTAL 202

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           ++G E  G+ +      D+   +P  G V SLNVS A+A+ LYE  R+R
Sbjct: 203 VLGSEGEGLRRLTGERCDEIARLPTGGPVGSLNVSNAAAVALYEVARRR 251


>UniRef50_Q0VMF8 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Alcanivorax
           RepID=Q0VMF8_ALCBS
          Length = 251

 Score =  196 bits (499), Expect = 5e-49,   Method: Composition-based stats.
 Identities = 45/167 (26%), Positives = 78/167 (46%), Gaps = 3/167 (1%)

Query: 2   NPTRYARICEMLA-RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
            P   + + + L  +    L + +E V  PHN+ A +R+ADA GV  V      +   T 
Sbjct: 82  RPLDESALLQWLDGKPAKPLLLVLENVTDPHNLGACLRSADAAGVQAVIVPRRNAAGLTP 141

Query: 61  A--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
                A G+   +       +   +  L+ +G+ ++ T L + +             ++M
Sbjct: 142 VACRTAVGAAESLAYYEIGNLASLLDQLRDRGVWVVGTALEERSESLFTFQAPESLAVVM 201

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           G E +G+ +      DQ + IPM G VQSLNVSVA+ ++L++ + QR
Sbjct: 202 GAEGSGLKRLTRDKCDQLLEIPMAGEVQSLNVSVATGVMLFQVRAQR 248


>UniRef50_UPI0001C31319 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Conexibacter
           woesei DSM 14684 RepID=UPI0001C31319
          Length = 256

 Score =  196 bits (499), Expect = 6e-49,   Method: Composition-based stats.
 Identities = 49/168 (29%), Positives = 82/168 (48%), Gaps = 5/168 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MR 58
           + P RYA + E+LA  +  L V ++++  P N+ AI RTA+  G   +      S     
Sbjct: 90  VAPFRYAYVDELLAV-EHPLIVALDEIQDPQNLGAIARTAECAGATGLVIPARRSADVTP 148

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP-TCIL 117
            +  A+AG+   + +   R + D +   +G G  +         V +  +DY+ P   ++
Sbjct: 149 AVCKASAGAVEHLPIARARNLADFLGDARGVGAWVYGAEGDGG-VPYTGVDYSGPGVVLV 207

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +G E  G+     A  D  I +P+ G + SLNVS A++ +LYE  RQR
Sbjct: 208 LGSEGRGLRPRVAASCDALIALPLRGRIGSLNVSAAASALLYEIVRQR 255


>UniRef50_Q7VQP0 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB n=2
           Tax=Candidatus Blochmannia RepID=RLMB_BLOFL
          Length = 254

 Score =  196 bits (499), Expect = 6e-49,   Method: Composition-based stats.
 Identities = 46/167 (27%), Positives = 76/167 (45%), Gaps = 5/167 (2%)

Query: 9   ICEMLARRQP--DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAA 64
           +   L  +     L + ++ +  PHN+ A IR+ADA GVH +      S     T+   A
Sbjct: 85  LLHFLKTKNNIIPLLLVLDGITDPHNLGACIRSADAAGVHMIIVPRDRSANVNATVRKVA 144

Query: 65  AGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTG 124
           +GS+  V       +   +  LK   + I+ + L  N +         P  ++MG E +G
Sbjct: 145 SGSSDRVPFVRVTNLSRTLKLLKKYNIYIVGSVLRSNQI-LFNTRLIDPIALVMGSESSG 203

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMY 171
           I +      D+ + IP +    SLNVSVA+ + L+E  RQR+    +
Sbjct: 204 IRRLTRENCDKLVHIPTLQSTVSLNVSVATGIFLFETVRQRKYQNGF 250


>UniRef50_C9A4E5 RNA methyltransferase n=3 Tax=Enterococcus casseliflavus
           RepID=C9A4E5_ENTCA
          Length = 259

 Score =  195 bits (498), Expect = 6e-49,   Method: Composition-based stats.
 Identities = 45/163 (27%), Positives = 78/163 (47%), Gaps = 6/163 (3%)

Query: 2   NPTRYARICEMLARRQPDL---TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
            P     + E   +    L    + ++ V  P NV  +IRTADA G   V      + + 
Sbjct: 94  TPQGIFAVVEKQEQDLQTLTGNWLILDNVQDPGNVGTMIRTADAAGFSGVFLGEGTADLY 153

Query: 59  --TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
              +  +  GSN  + +     I   +  L+  G+ I  T L+  AV + E+   +    
Sbjct: 154 STKVLRSMQGSNYHLPIVEGA-IPPFLKQLQAAGVAIYGTELNKEAVPYTELPKGQAAAF 212

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILY 159
           ++G E  G+ QE LAL D+++ IP+ G  +SLNV++A+ +++Y
Sbjct: 213 ILGNEGQGVNQELLALTDKNLYIPIYGQAESLNVAIAAGILMY 255


>UniRef50_Q11YB9 tRNA/rRNA methyltransferase, TrmH family n=24 Tax=Bacteroidetes
           RepID=Q11YB9_CYTH3
          Length = 268

 Score =  195 bits (498), Expect = 7e-49,   Method: Composition-based stats.
 Identities = 51/174 (29%), Positives = 85/174 (48%), Gaps = 7/174 (4%)

Query: 1   MNPTRYARICEM----LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++   +A +  +        +  L V +++V    N  A+ R+A+ +GV  +     G+ 
Sbjct: 93  LSAINFASLDNIVSACFESGKNPLLVMLDRVTDVRNFGAVARSAECLGVDAMIVPSRGAA 152

Query: 57  --MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
                    +AG+   + V     + D V +LK  G++I+A      +++  + D T P 
Sbjct: 153 QLNSDAVKTSAGALYHIPVCRVDHLIDTVKYLKQCGLRIIACS-EKASINVYDEDLTDPC 211

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
            ILMG E+ GI+ + L  AD  + IPM G + SLNVSVA+ +IL E  RQR   
Sbjct: 212 VILMGSEEDGISMDLLRYADAHVTIPMSGHINSLNVSVATGMILSEVTRQRLKQ 265


>UniRef50_Q2S2J6 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Rhodothermaceae
           RepID=Q2S2J6_SALRD
          Length = 253

 Score =  195 bits (498), Expect = 7e-49,   Method: Composition-based stats.
 Identities = 45/175 (25%), Positives = 77/175 (44%), Gaps = 12/175 (6%)

Query: 2   NPTRYARICEMLARRQP---------DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW 52
            P RY  +  ML+   P          + + +++V  P N  A++R+A A G   V    
Sbjct: 79  APIRYREVDAMLSDIAPTWDAVQTAQPMLLVVDRVTDPRNFGAMLRSAVAAGTDGVIVPT 138

Query: 53  PGSRMRTM--ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDY 110
                       A+AG+   + +     +   +  LK +G  +     +       + D+
Sbjct: 139 REMAPLNAAAIKASAGTAPRIPIARTDDLPRVLTQLKERGYFVYGAEGTAE-TPLWDADW 197

Query: 111 TRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            RP  +++G E  G+  E     D+ + IPM G  +SLNVSVA+ L+++EA R R
Sbjct: 198 DRPVAVVLGSEGQGLAPEVAEACDELLSIPMRGPAESLNVSVATGLLVFEAARSR 252


>UniRef50_C1ZH70 rRNA methylase, putative, group 3 n=1 Tax=Planctomyces limnophilus
           DSM 3776 RepID=C1ZH70_PLALI
          Length = 271

 Score =  195 bits (498), Expect = 8e-49,   Method: Composition-based stats.
 Identities = 46/166 (27%), Positives = 79/166 (47%), Gaps = 3/166 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP--GSRMR 58
           M    YA    +   + P L V ++ +    N+ AIIR A+A+G   +            
Sbjct: 103 MPEFPYADFEGLFQAQLPALLVILDGIQDSFNLGAIIRCAEALGAGGIVLPEKGQSGVNS 162

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
             A ++AG+ +++ +     +  A+  LK +GM+ILA     +      +    P C+++
Sbjct: 163 QAARSSAGAVNFLPIYRVPALDRAIDQLKSRGMKILAAT-EKSEQSLWNVVIPAPLCLII 221

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
           G E  G++   L+  D  + IPM G   SLN +VA+ ++L E QRQ
Sbjct: 222 GNEGKGVSSALLSACDIQVRIPMAGQTSSLNAAVAAGILLAEIQRQ 267


>UniRef50_A7HIF7 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Anaeromyxobacter
           RepID=A7HIF7_ANADF
          Length = 239

 Score =  195 bits (496), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 67/206 (32%), Positives = 108/206 (52%), Gaps = 1/206 (0%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT- 59
           + P R ARI  ++A R   LTV ME    P NV+A++RT +A G+ E+H +    +    
Sbjct: 26  LVPERRARIDAVVANRTRTLTVVMEAFCDPQNVNAVLRTCEAFGIQELHVIEGPMKPYDR 85

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
               +  ++ WV V+   + G+ +AHLK +G  I ATHL + A     + +     ++ G
Sbjct: 86  NKKISQNADKWVDVRRWSSTGECLAHLKAEGFAIYATHLGEGARTLDALSFAGKVALVFG 145

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E  G++ EA+AL+D   +IPM G VQSLNVSVA+A+ + +A  +R        + S L 
Sbjct: 146 NEHRGVSDEAVALSDAVYVIPMHGFVQSLNVSVAAAISIAKAVERRAAERGRHGDLSELE 205

Query: 180 EAEQQRLLFEGGYPVLAKVAKRKGLP 205
            A  +   +       A++AK + + 
Sbjct: 206 AAALRERFYVLAVKQRARIAKAERVD 231


>UniRef50_Q8EPH3 rRNA methylase n=1 Tax=Oceanobacillus iheyensis RepID=Q8EPH3_OCEIH
          Length = 246

 Score =  194 bits (495), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 49/167 (29%), Positives = 80/167 (47%), Gaps = 7/167 (4%)

Query: 2   NPTRYARICEM---LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
            P     + EM     +   +L + ++ +  P N+  IIRTADA GV  V        + 
Sbjct: 82  TPQGVIAVVEMNIPKVQEDNNLIILLDAIQDPGNMGTIIRTADAAGVDAVVLGDGCVDIF 141

Query: 59  T--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
              +  A  GS   + + T   +   +  L+ QG  ILAT L D AV++ E+       +
Sbjct: 142 NDKVIRATQGSIFHIPIYTAT-LEQEIHMLQTQGFTILATALHD-AVEYTEVSVHNKVGL 199

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           ++G E  GI    L  A+Q I IP+ G  +SLNV +A+ +++Y  ++
Sbjct: 200 ILGNEGAGIAPSLLNKANQRINIPIYGKAESLNVGIAAGILMYHLKK 246


>UniRef50_C0X8M7 RNA methyltransferase n=36 Tax=Enterococcus RepID=C0X8M7_ENTFA
          Length = 258

 Score =  194 bits (495), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 40/165 (24%), Positives = 82/165 (49%), Gaps = 8/165 (4%)

Query: 2   NPTRYARICEMLARRQPDL-----TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
                  I  +  +++  L      + ++ +  P NV  +IRTADA G+  V      + 
Sbjct: 89  TSQGILAIVTLETQQEQSLSFKGGWLLLDNIQDPGNVGTMIRTADAAGLAGVILGKGTAD 148

Query: 57  MRT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
           +    +  +  GS+  + V   R + + V   K QG+ +  T L++ A+ + E +     
Sbjct: 149 IYNTKVLRSMQGSHYHLPVLQ-RELTEVVQAFKKQGLPVFGTELNEAAIAYYEQEAVENY 207

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILY 159
            +++G E +G++ E LA   +++ IPM G  +SLNV++A+ ++++
Sbjct: 208 ALILGNEGSGVSPELLAETTKNLYIPMKGQAESLNVAIAAGVLMF 252


>UniRef50_B1GYT1 23S rRNA methyltransferase n=1 Tax=uncultured Termite group 1
           bacterium phylotype Rs-D17 RepID=B1GYT1_UNCTG
          Length = 251

 Score =  194 bits (495), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 44/173 (25%), Positives = 79/173 (45%), Gaps = 7/173 (4%)

Query: 1   MNPTRYARICEMLARRQP---DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           ++P +Y  + +++ R +     L V ++ +  PHN+ AIIR   A G   V      +  
Sbjct: 81  VSPVQYTELSDLIERSKKSLKPLLVILDGLEDPHNLGAIIRNCVAFGADGVIIPKWRAAG 140

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              T++ ++AG+   + +        A+  LK     I+            +ID   P  
Sbjct: 141 VNETVSKSSAGAVEHISISRVENTNQAIGLLKENSFWIVGAENGG--RILEKIDLPFPLA 198

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           +++G E  G+       +D  I IP   ++ SLN S ASA+ILYE  ++R+ +
Sbjct: 199 VIIGSEGFGLHSLTKKNSDFLISIPQENIISSLNASCASAVILYEIAKKRKIS 251


>UniRef50_B3ETE6 Putative uncharacterized protein n=1 Tax=Candidatus Amoebophilus
           asiaticus 5a2 RepID=B3ETE6_AMOA5
          Length = 246

 Score =  194 bits (494), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 52/173 (30%), Positives = 86/173 (49%), Gaps = 7/173 (4%)

Query: 1   MNPTRYARI----CEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++P     +     +   + +  L + ++ V    N+ AI+RTA  VG H +     GS 
Sbjct: 74  LSPVPLVTLSHIVQDTYEKGELPLIIILDGVTDVGNLGAIVRTAVCVGAHALVLPKQGSA 133

Query: 57  M--RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
                    +AG+ + + +     +  ++ +L+  G+Q++A H         ++  T PT
Sbjct: 134 SLGSGAMKTSAGALAHLPICREANLQASINYLQNSGLQVIACH-EKTQTSIYQVKLTVPT 192

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
            IL+G E  GI  + L   D    IPM+G + SLNVSVA+A+ILYE+ RQR N
Sbjct: 193 AILLGSEDKGIQPQLLNKVDVQASIPMVGPISSLNVSVAAAIILYESFRQRNN 245


>UniRef50_B8D292 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Halothermothrix orenii H
           168 RepID=B8D292_HALOH
          Length = 270

 Score =  194 bits (494), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 46/181 (25%), Positives = 90/181 (49%), Gaps = 15/181 (8%)

Query: 2   NPTRYARICEM--------LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP 53
           NP   A I  +           R   + + ++++  P N+  IIRTA A G+  +  +  
Sbjct: 92  NPQGIAAITYVPRSGANILFHNRNRGIILILDRIQDPGNMGTIIRTAVAAGIEGIICLKG 151

Query: 54  GSRMRT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQ--GMQILATHLSDNAVDFREID 109
              +    +  A+ G+   + + T  +    +  ++ +    +++ T L+  +  + EID
Sbjct: 152 SVDIYNLKVIRASMGAIFSIPILTGVSFKR-LQKIRDEYPDYKLICTDLN-TSKFYHEID 209

Query: 110 YTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEA-QRQRQNA 168
           Y  P  +++G E  GI +E L+LAD  I IP++G + SLN +V++A++LY+   + R + 
Sbjct: 210 YQEPLMLVIGNEARGIREELLSLADIKIKIPLMGNIDSLNAAVSTAIVLYDIVVKCRHSN 269

Query: 169 G 169
           G
Sbjct: 270 G 270


>UniRef50_Q7TU91 tRNA/rRNA methyltransferase n=3 Tax=Prochlorococcus marinus
           RepID=Q7TU91_PROMP
          Length = 428

 Score =  194 bits (493), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 43/157 (27%), Positives = 69/157 (43%), Gaps = 7/157 (4%)

Query: 8   RICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMA 61
            + +++     +    + V ++ V  PHN  AIIR+A+A     +      S     T+A
Sbjct: 267 SLEKLIDISKSKSSNPIIVALDGVTDPHNFGAIIRSAEAFDCKGIIVPQRRSAGLTGTVA 326

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
             AAG+   + V     +  A+  LK +G  I+     D  V   E     P  +++G E
Sbjct: 327 KVAAGALEHIPVSRVVNLNRAIDELKKKGFIIIGLS-GDGQVPISEFKEKAPVVVIVGAE 385

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALIL 158
             GI+       D  + IP+ G   SLN SVA+A+ L
Sbjct: 386 NKGISLLVQKKCDYLLKIPLKGKTSSLNASVAAAISL 422


>UniRef50_D1NAJ1 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Victivallis vadensis
           ATCC BAA-548 RepID=D1NAJ1_9BACT
          Length = 273

 Score =  194 bits (493), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 49/174 (28%), Positives = 85/174 (48%), Gaps = 11/174 (6%)

Query: 2   NPTRYARICEMLAR-------RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG 54
            P     I +M          R   L +  E V KP N+ +++R+ADA GV         
Sbjct: 95  RPEGLIAIAKMKRHTLAEMPVRPNGLYLVAEAVEKPGNLGSMLRSADAAGVDGFIICNKC 154

Query: 55  SRMRT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR 112
           + +    +  A+ G+   V +       +A   LK   ++ LA     + + + ++D T+
Sbjct: 155 TDIYNPNVIRASTGALFSVPLAEAEN-QEAYDWLKKNNIRTLAATPHTDQI-YTDVDMTQ 212

Query: 113 PTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
              I++G E+TG+T+  +  +D  + IPM+G + SLNV+ A+ ++LYEA RQR 
Sbjct: 213 AVAIVVGTEQTGLTELWMEHSDLPVRIPMLGKIDSLNVATATTILLYEAARQRN 266


>UniRef50_B5YF75 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Dictyoglomus
           RepID=B5YF75_DICT6
          Length = 241

 Score =  194 bits (493), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 47/163 (28%), Positives = 81/163 (49%), Gaps = 6/163 (3%)

Query: 3   PTR-YARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA 61
           P R +  I + L  +   + V ++ +  PHN+ AI RT++  G   +      S   T A
Sbjct: 77  PYREWEDIEKTLNNK--SVIVVLDHIQDPHNLGAIARTSEFAGASAIVIPKARSAGVTSA 134

Query: 62  --SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
              A+AG+ S++ V     I + +  LK +G  I+   L    + + +++Y  P  +++G
Sbjct: 135 SFKASAGALSYIPVVRVSNIANFLRELKKKGWFIVGADLDTENL-YNQVNYRFPLALVVG 193

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
            E  G+ +      D  + IP  G V+SLNVSVA  +ILY+ +
Sbjct: 194 SEDEGLHRIVKESCDLLVKIPSYGKVESLNVSVALGIILYKIR 236


>UniRef50_D1Y8A8 RNA methyltransferase, TrmH family, group 3 (Fragment) n=1
           Tax=Pyramidobacter piscolens W5455 RepID=D1Y8A8_9BACT
          Length = 269

 Score =  194 bits (493), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 42/165 (25%), Positives = 69/165 (41%), Gaps = 3/165 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT- 59
           + P     + + L  + P L V ++    PHN+ A+IRTA+  G   V      S     
Sbjct: 96  IPPADLDGVVDALDPQAPALIVLLDHCQDPHNLGAVIRTAEVAGAACVVCQNDRSATVNG 155

Query: 60  -MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
            +   +AG+   + V     +G AV  LK +G  ++      +              +++
Sbjct: 156 TVVKTSAGAAFRLPVAQVVNVGRAVERLKRKGFWVVGLDHRTDET-VWSSALPERLALVV 214

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           G E  GI+       D  +  PM G   +LN SVA+AL ++E  R
Sbjct: 215 GSEGEGISALTAKKCDMLVKFPMAGRTGNLNASVAAALGMFEWVR 259


>UniRef50_A5F9W1 tRNA/rRNA methyltransferase (SpoU) n=16 Tax=Bacteroidetes
           RepID=A5F9W1_FLAJ1
          Length = 220

 Score =  193 bits (492), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 51/207 (24%), Positives = 103/207 (49%), Gaps = 4/207 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           +   R  +  ++L  R    T+ +E V++ HN SA++R+ +  G+ E++ +      R  
Sbjct: 14  LTDNRKEKFLKVLENRTKHFTIAVEDVYQMHNTSAVMRSCEVFGIQELNIIEQRFGKRID 73

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              A G+  WV +    T+   ++ L+ +G QI+AT   +N    ++ D ++P+ +  G 
Sbjct: 74  KEIALGAQKWVDINRFDTVDGCISSLRDKGYQIIATTPHENDCLIQDFDISKPSALFFGT 133

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           EK G++ E L  AD  + IPM+G  +SLN+SV++A+I+     + +N+ +       L +
Sbjct: 134 EKDGLSPEILEKADGFLKIPMVGFTESLNISVSAAIIIQNLTNRLRNSDI----KWKLSD 189

Query: 181 AEQQRLLFEGGYPVLAKVAKRKGLPYP 207
            E  +   +     +  + + +   Y 
Sbjct: 190 EEILQKRLDWAKNSIRDIKRIEARYYQ 216


>UniRef50_B5JMU7 RNA methyltransferase, TrmH family n=1 Tax=Verrucomicrobiae
           bacterium DG1235 RepID=B5JMU7_9BACT
          Length = 273

 Score =  193 bits (491), Expect = 4e-48,   Method: Composition-based stats.
 Identities = 44/173 (25%), Positives = 84/173 (48%), Gaps = 11/173 (6%)

Query: 2   NPTRYARI-------CEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG 54
            P     +        + L    P   + +E + KP N+  I+R+ADA GV  V      
Sbjct: 96  RPEGLLAVIKQWNHTLDDLQLSDPPFLLIVEAIEKPGNLGTILRSADAAGVDAVICCDSV 155

Query: 55  SRMRTM--ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR 112
           + +       ++ G    +   T  +  + +  ++ +G++ +AT    + + + + D   
Sbjct: 156 TDLFNPNAVRSSTGVLFSMPTVTASS-DEVIKWIRQKGIRTIATTPHTD-ILYTDTDLRG 213

Query: 113 PTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           P  I+MG E+ G++++ L+  D  ++IPM G   SLNV++A+ + L+EA RQR
Sbjct: 214 PLAIVMGSEQFGLSEKWLSACDTKVLIPMAGQADSLNVAMATLITLFEAVRQR 266


>UniRef50_D1J7J9 tRNA/rRNA methyltransferase n=2 Tax=Mycoplasma RepID=D1J7J9_MYCHP
          Length = 230

 Score =  193 bits (491), Expect = 5e-48,   Method: Composition-based stats.
 Identities = 41/162 (25%), Positives = 77/162 (47%), Gaps = 4/162 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP--GSRMR 58
           +   +Y  +  +  +   D  + ++ +  P N  AIIR+A+  G   +            
Sbjct: 64  LKDFQYHDLGSIF-KDGSDKVLILDHIQDPQNFGAIIRSANVFGFKHIIIPKDRACDVTP 122

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
           ++   ++G    V+V    ++ DA+  LK +G  I A+ L+  A    +  +     I++
Sbjct: 123 SVLKTSSGGFKNVKVIKVNSLFDAIEELKNKGFWIYASALNQQAKKLNDAKFNEKIAIIV 182

Query: 119 GQEKTGITQEALALADQDIIIPM-IGMVQSLNVSVASALILY 159
           G E +G+++  L  +D+ I I      VQSLNVSVA+ ++LY
Sbjct: 183 GNEGSGVSKTLLKHSDEIIYIEQDKESVQSLNVSVATGILLY 224


>UniRef50_A9KHD7 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Clostridium
           phytofermentans ISDg RepID=A9KHD7_CLOPH
          Length = 264

 Score =  192 bits (490), Expect = 6e-48,   Method: Composition-based stats.
 Identities = 44/176 (25%), Positives = 82/176 (46%), Gaps = 10/176 (5%)

Query: 1   MNPTRYARI-------CEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP 53
           + P     I        + +        + +E +  P N+  ++RTA+ VG+  +     
Sbjct: 89  ITPQGILAIVKQPIYTLKDMTSGDSIRLLLLEDIRDPGNLGTMVRTAEGVGMTGIVLSKD 148

Query: 54  GSR--MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYT 111
                   +  +  G+   V           +  +K + + I A HL   AV + ++ Y 
Sbjct: 149 SVDMFNPKVIRSTMGAIFRVPFFYAEDFYACLNQIKNEEIAIYAAHL-QGAVWYDKVSYQ 207

Query: 112 RPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
             + IL+G E  G++ +A +L+ Q I IPM G V+SLN ++A+A+++YE+ RQ +N
Sbjct: 208 GKSAILIGNEANGLSDKATSLSTQRIKIPMEGNVESLNAAIAAAVLMYESYRQIRN 263


>UniRef50_B5CKU5 Putative uncharacterized protein n=1 Tax=Ruminococcus lactaris ATCC
           29176 RepID=B5CKU5_9FIRM
          Length = 279

 Score =  192 bits (490), Expect = 6e-48,   Method: Composition-based stats.
 Identities = 45/151 (29%), Positives = 73/151 (48%), Gaps = 3/151 (1%)

Query: 19  DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTH 76
              + ++ +  P N+  I RTA+A G   +        +    +  +  G+   +     
Sbjct: 130 PHVIVLDNLQDPGNLGTIFRTAEAAGATGILLSSDSVDVYNPKVIRSTMGAVFRMPFFYV 189

Query: 77  RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQD 136
           + +  AV  L  QG++  A HL+   V + E DYT     L+G E  G+  E    AD  
Sbjct: 190 KDLPAAVKSLSSQGIRTYAAHLNGKNV-YDEEDYTEGCAFLIGNEGNGLRDEVSECADCL 248

Query: 137 IIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
           I IPM G  +SLN +VA+A++++EA RQR+ 
Sbjct: 249 IRIPMCGKAESLNAAVAAAVLMFEAGRQRRK 279


>UniRef50_A0M5B1 TrmH family tRNA/rRNA methyltransferase n=16 Tax=Bacteroidetes
           RepID=A0M5B1_GRAFK
          Length = 245

 Score =  192 bits (489), Expect = 8e-48,   Method: Composition-based stats.
 Identities = 53/171 (30%), Positives = 82/171 (47%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARICEMLARRQP----DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++P  +  + +++   Q      L V ++ +    N  AIIRTA+  GV  +     GS 
Sbjct: 75  ISPIGFVSLEKLVEDSQKSSTTPLFVLLDGITDVRNFGAIIRTAECCGVTGIIIQEKGSA 134

Query: 57  MRTM--ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
                    +AG+   + +     I DAV HL+   ++++A     + V   +ID  +P 
Sbjct: 135 PINADTVKTSAGAVFNIPICKVNHIKDAVFHLQTYDIKLIAATEKTDDV-IFDIDLKQPI 193

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
            I+MG E  GI+   L   D    +PM+G + SLNVSVA    LYEA RQR
Sbjct: 194 AIIMGDEAKGISNSILKSVDYKAKLPMLGSIASLNVSVACGAFLYEAVRQR 244


>UniRef50_Q3A6R3 rRNA methyltranferase n=2 Tax=Desulfuromonadales RepID=Q3A6R3_PELCD
          Length = 246

 Score =  192 bits (489), Expect = 8e-48,   Method: Composition-based stats.
 Identities = 36/168 (21%), Positives = 68/168 (40%), Gaps = 6/168 (3%)

Query: 4   TRYARICEMLA----RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP--GSRM 57
                + ++L          + + ++ +  PHN+ A+ R+A+AVG   +           
Sbjct: 77  QSVIALEDLLDLWRNAGGKGVILVLDGITDPHNLGALARSAEAVGCQGIVLPKDRSCPIT 136

Query: 58  RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
                A+AG+ +++ V     +  ++   K  G  +        +    + D      ++
Sbjct: 137 AAAEKASAGALAYLPVCRVTNVARSLEVFKQAGFWVYGLAGDAGSQSLYDTDLRGNVVLV 196

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           +G E  G+        D  + IPM G V SLN SVA  + L+E  RQ+
Sbjct: 197 VGGEGKGLRDNVRKHCDALLAIPMRGQVSSLNASVAGGVALFEVLRQQ 244


>UniRef50_UPI000196B15F hypothetical protein CATMIT_01248 n=1 Tax=Catenibacterium mitsuokai
           DSM 15897 RepID=UPI000196B15F
          Length = 242

 Score =  192 bits (489), Expect = 9e-48,   Method: Composition-based stats.
 Identities = 37/162 (22%), Positives = 73/162 (45%), Gaps = 7/162 (4%)

Query: 2   NPTRYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT 59
            P     +C       +  D  + ++ V  P N+  I+R+A A G  ++        +  
Sbjct: 77  TPQPIMAVCHKKDNILKHYDRVLILDGVQDPGNLGTILRSALAFGFKQIVMSPDCVDLYN 136

Query: 60  --MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
                +  G+   + +     +   +  L+  G++++AT L  NA    +I  T     +
Sbjct: 137 DKALRSTQGAVFHLDIVR-DDLHHVIPELQKLGVRVIATSLH-NASSIDDIKSTDKMAFV 194

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILY 159
           MG E  G+  E +A++D  + IP+   ++SLNV VA+ +++Y
Sbjct: 195 MGNEGNGVRDETIAMSDASLYIPID-TMESLNVGVAAGIVMY 235


>UniRef50_A1WUS8 RNA methyltransferase, TrmH family, group 3 n=8 Tax=Proteobacteria
           RepID=A1WUS8_HALHL
          Length = 271

 Score =  192 bits (488), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 46/175 (26%), Positives = 82/175 (46%), Gaps = 4/175 (2%)

Query: 2   NPTRYA-RICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--R 58
            P R    + +++      L + +++V  PHN+ A +R+A A G H V A    +     
Sbjct: 98  TPARGEGELADLVDAEPEPLLLVLDRVQDPHNLGACMRSAAAAGAHGVVAPRDRAAALSP 157

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
            +   AAG+   +       +   +  L+  G+ ++     +      E+D   P  +++
Sbjct: 158 AVHKTAAGAVQRIPFFQVTNLARTLQQLRDAGVHVVGAA-GEAEKSCYEVDLRGPLALVL 216

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLR 173
           G E  G+ +      D+ + IPM G ++SLNVSVA+ ++L+EA RQR   G  L 
Sbjct: 217 GGEGEGLRRLTRERCDERVAIPMPGSMESLNVSVAAGVLLFEAVRQRFPQGGDLG 271


>UniRef50_C8NEH0 TrmH family RNA methyltransferase n=2 Tax=Granulicatella
           RepID=C8NEH0_9LACT
          Length = 256

 Score =  192 bits (488), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 42/163 (25%), Positives = 78/163 (47%), Gaps = 6/163 (3%)

Query: 2   NPTRYARICEMLAR---RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
                  + E++ +         + ++ V  P N+  I+RTADA G   V        + 
Sbjct: 88  TAQGILAVVEIVKQEILPHKGRFIVLDAVQDPGNLGTIVRTADAAGFDAVVLGTGTVDLY 147

Query: 59  T--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
              +  +  GS+  + V     + + +  LK +G+Q+  T L  ++ D+  +       I
Sbjct: 148 NDKVLRSMQGSHFHIPVFQ-ANLQEYLPILKEKGVQVAVTALHRDSKDYSVLQGATDVAI 206

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILY 159
           ++G E  G++ + + LAD  + IP+ G  +SLNVS+ASAL++Y
Sbjct: 207 VVGNEGQGVSDDVIDLADVVVTIPIFGKAESLNVSIASALLMY 249


>UniRef50_B1I0T3 RNA methyltransferase, TrmH family, group 3 n=2 Tax=Clostridia
           RepID=B1I0T3_DESAP
          Length = 251

 Score =  192 bits (488), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 51/172 (29%), Positives = 84/172 (48%), Gaps = 4/172 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           ++   +A + E+L   +  L V +  +  P N+ AI+RTA+A GV         +   T 
Sbjct: 81  VSVKDFATVEELLGT-ENPLIVVLNAIQDPRNLGAILRTAEAAGVDGAVVPSRRAAPLTP 139

Query: 61  ASAAAGS--NSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
           A+A   +    ++ V     I   +   K +G+ ++     D  V + + D   P  +++
Sbjct: 140 AAAKTAAGAVEYLPVARVTNIALTLREFKQKGLWVVGADP-DGPVSYWDADLGGPLALVI 198

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGM 170
           G E  G+ +   A  D  + IPM G V SLN SVA+AL++YEA RQR+  G 
Sbjct: 199 GGEAGGLGRAVRAECDSLVRIPMSGRVGSLNASVAAALLIYEAVRQRRAGGS 250


>UniRef50_B8DUY4 tRNA/rRNA methyltransferase n=5 Tax=Bifidobacterium
           RepID=B8DUY4_BIFA0
          Length = 331

 Score =  192 bits (488), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 43/187 (22%), Positives = 79/187 (42%), Gaps = 20/187 (10%)

Query: 3   PTRYARICEMLARRQP------------------DLTVCMEQVHKPHNVSAIIRTADAVG 44
           P +Y+ + E++ R +                    L + ++ +  P N+ A+IR+A A G
Sbjct: 141 PFQYSSLHELVERAERKARAMEMADSKASRLSARPLFIALDGITDPQNLGAVIRSAAAFG 200

Query: 45  VHEVHAVWPGSRMRTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNA 102
           V+ V      S     A    +AG+ + + +     +  A+  LK +G   +      + 
Sbjct: 201 VNGVILPERRSASVNAAAWKVSAGAAAHMPIARVVNLTKAIEALKERGYYSIGLDGGGSK 260

Query: 103 VDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
           +       T P  +++G E  G+++      D    IP+   V+SLN SVA+ + LY   
Sbjct: 261 LVGETGFETDPLVVVLGSEGKGLSRLTREACDAIASIPITSAVESLNASVAAGIALYATV 320

Query: 163 RQRQNAG 169
             R+ AG
Sbjct: 321 NARRKAG 327


>UniRef50_D0MG21 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Rhodothermus marinus DSM
           4252 RepID=D0MG21_RHOM4
          Length = 259

 Score =  191 bits (487), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 61/199 (30%), Positives = 98/199 (49%), Gaps = 5/199 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           +   R  RI ++L  R   +   +E +    NVSA++R+A+A+G      +    +    
Sbjct: 52  LTERRRQRIEQVLDGRTYTVVPVVEGLANTGNVSAVMRSAEALGYQGFGIIKGQVQKYKT 111

Query: 61  A-SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
           +   A G++ W+ V T  T  +AV  LK  G +I+AT L + A      D+T PT ++ G
Sbjct: 112 SERTAQGADKWLDVWTWPTAAEAVPALKAAGYRIVATAL-EEAEPIDTFDFTVPTALVFG 170

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E  G+++E LA+AD   +IP++G  QS N+SVA+A+ LY AQR R         +  L 
Sbjct: 171 NEVEGVSRELLAMADARCVIPIVGFTQSFNISVAAAIALYHAQRDRLA---RRGRHGDLS 227

Query: 180 EAEQQRLLFEGGYPVLAKV 198
              +  L        + K 
Sbjct: 228 PEWKATLRAVFYLRSVQKA 246


>UniRef50_C9M6N6 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Jonquetella
           anthropi E3_33 E1 RepID=C9M6N6_9BACT
          Length = 278

 Score =  191 bits (486), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 44/169 (26%), Positives = 80/169 (47%), Gaps = 5/169 (2%)

Query: 7   ARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMAS 62
             + ++L +    P L + +++   PHN+ ++IRTA+A G   V      S     T+  
Sbjct: 111 VSLDDLLDQLAGGPALVILLDRCQDPHNLGSVIRTAEAAGASAVLVPKDRSVRLTGTVVK 170

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
           A+AG+     V +   +  A+  LK  G  ++     +++    ++ + + T + +G E 
Sbjct: 171 ASAGAALRFPVISVVNVKRALDDLKEAGFWVVGLA-GESSEPLGKLAWDQRTVLAVGAEG 229

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMY 171
           TG+ +      D    IPM G  +SLN  VA+AL  YE  R+   +G +
Sbjct: 230 TGLAELTRKSCDFLARIPMSGQAESLNAGVAAALGAYEWARRFHFSGDF 278


>UniRef50_D1AU26 RNA methyltransferase n=1 Tax=Anaplasma centrale str. Israel
           RepID=D1AU26_ANACI
          Length = 262

 Score =  191 bits (486), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 40/168 (23%), Positives = 69/168 (41%), Gaps = 5/168 (2%)

Query: 5   RYARICEMLARR--QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA- 61
              R+ ++++         V ++QV   +NV AI+R+A    V  V      S       
Sbjct: 92  DKLRVEDIVSGSAFTASTVVLLDQVTDINNVGAIVRSAACFDVDAVILPEHHSPSENCII 151

Query: 62  -SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              ++G+   V V     +   + +LK  G       +  +     EI +     I++G 
Sbjct: 152 TRVSSGAADLVPVVRVGNLVKTMEYLKQNGYWCYGMDVDGD-KALHEISFCERRAIILGS 210

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           E  GI +      D  + IPM   + SLNVS A+A++LY +  Q   +
Sbjct: 211 EGKGIRRLTREHCDHLVKIPMSARINSLNVSNAAAIVLYSSYLQLHRS 258


>UniRef50_A5EVE3 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Dichelobacter
           nodosus VCS1703A RepID=A5EVE3_DICNV
          Length = 242

 Score =  190 bits (485), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 38/158 (24%), Positives = 73/158 (46%), Gaps = 3/158 (1%)

Query: 10  CEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGS 67
            + ++  +    + ++ +  PHN+ A +RTA A GV  V      +      +   A G+
Sbjct: 83  QQAISGVERPFILVLDSIQDPHNLGACLRTAMAAGVDAVVLPNSCAADITPVVRKIACGA 142

Query: 68  NSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQ 127
              + +     +   V  +K +G+ ++     +      ++D +    +++G E+ GI  
Sbjct: 143 AEALAIFRVANLKREVEMMKEKGLWVVGGA-GEAEKSLFDLDLSGGLVMIVGNEEKGIHY 201

Query: 128 EALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
                 D    IPM   ++SLNVSVA  ++L+EA+RQR
Sbjct: 202 GLRQTCDWLAAIPMAETMESLNVSVACGIMLFEARRQR 239


>UniRef50_P94538 Uncharacterized tRNA/rRNA methyltransferase ysgA n=110
           Tax=Bacillales RepID=YSGA_BACSU
          Length = 248

 Score =  190 bits (485), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 44/165 (26%), Positives = 81/165 (49%), Gaps = 6/165 (3%)

Query: 2   NPTRYARICEMLARR--QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT 59
            P + A +C M   +       + ++ V  P N+  +IRTADA G+  V      +    
Sbjct: 85  TPQQIAAVCHMPEEKLATARKVLLIDAVQDPGNLGTMIRTADAAGLDAVVLGDGTADAFN 144

Query: 60  --MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
                +A GS+  + V   R +   V  LK +G+++  T L + A  ++EI  +    ++
Sbjct: 145 GKTLRSAQGSHFHIPVVR-RNLPSYVDELKAEGVKVYGTALQNGA-PYQEIPQSESFALI 202

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
           +G E  G+    L   D ++ +P+ G  +SLNV+VA+A+++Y  +
Sbjct: 203 VGNEGAGVDAALLEKTDLNLYVPLYGQAESLNVAVAAAILVYHLR 247


>UniRef50_Q2RFM6 RNA methyltransferase TrmH, group 3 n=2 Tax=Clostridia
           RepID=Q2RFM6_MOOTA
          Length = 246

 Score =  190 bits (485), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 51/171 (29%), Positives = 86/171 (50%), Gaps = 7/171 (4%)

Query: 4   TRYARICEMLAR----RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--M 57
             YA + ++LAR     +P   + +++V  PHN+ AI+R+A+AVG H V           
Sbjct: 75  REYADLEDLLARAGEAGEPPFLIMLDRVEDPHNLGAILRSAEAVGAHGVIIPRRRGVGLT 134

Query: 58  RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
             +A AA G+  +V V     +   +  LKG+G+  +          F   D+T P  ++
Sbjct: 135 AAVARAAVGAQEYVPVARVTNLARTLEELKGKGLWAIGAAGDAGQEAF-NADFTVPLVLV 193

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           +G E  G++    +  D  + +PM G + SLNV+ A+ +++YE  RQR  A
Sbjct: 194 LGSEGRGLSPLVRSRCDFTVHLPMRGRINSLNVATAATVLMYEVLRQRGQA 244


>UniRef50_Q2S465 RRNA methylase n=1 Tax=Salinibacter ruber DSM 13855
           RepID=Q2S465_SALRD
          Length = 247

 Score =  190 bits (484), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 57/214 (26%), Positives = 98/214 (45%), Gaps = 7/214 (3%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT- 59
           M   R  RI  ++A R   +   +E +    NVSA++R+A+A+G  ++H V         
Sbjct: 38  MRERRLDRIQTVVANRTRSVVPVVEGLVNTGNVSAVMRSAEALGHQDMHVVSGEHDRYKH 97

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
               A G+  W+ V           HL+  G +++A HL  + V  R++D+T+PT ++ G
Sbjct: 98  SQRTAQGAQHWLDVWHWDAPTACATHLQDAGYRVVAMHLHADTVPIRDLDFTQPTALVFG 157

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E  G+T   L  +D    +P+ G  +S NVSVA+A+ LY AQ+ R         ++ L 
Sbjct: 158 NEDAGVTDTMLEASDAACEVPLPGFTESFNVSVAAAVALYHAQQDRL---DRQGHHADLS 214

Query: 180 EAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQG 213
           +  + RL        +    +        +  +G
Sbjct: 215 DEARARLEARFCLRSVNNAEQIIER---KLGDEG 245


>UniRef50_C9RBD1 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Ammonifex
           degensii KC4 RepID=C9RBD1_AMMDK
          Length = 254

 Score =  190 bits (484), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 54/179 (30%), Positives = 82/179 (45%), Gaps = 5/179 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MR 58
           ++P  YA + E+LA   P   + +  +  P N+ AI+RTA AVGV  V      +     
Sbjct: 79  VSPYNYASLDEILAT-HPSCLLVLAYITDPRNLGAILRTAAAVGVEGVIIPSRRAAGLTA 137

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
               A+AG    V+V     +   + +LK QG  +L        V   E ++  P  +++
Sbjct: 138 EALKASAGGAEHVKVARVTNLAQTLRYLKEQGFWVLGAEADAK-VSLWEAEWNEPLVVVI 196

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSM 177
           G E TG+ +      D  + IP    +  LN SVA+A+ILYE  R RQ  G    +N  
Sbjct: 197 GGEDTGLGKVVRRECDVLVRIPTTAKMPCLNASVAAAVILYEVLR-RQMKGKNAGDNLD 254


>UniRef50_C8W818 RNA methyltransferase, TrmH family, group 3 n=7
           Tax=Coriobacteriaceae RepID=C8W818_ATOPD
          Length = 338

 Score =  190 bits (484), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 43/170 (25%), Positives = 72/170 (42%), Gaps = 5/170 (2%)

Query: 3   PTRYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           P  YA + E++ R      L V ++ V    N  AI+R+A+ VG   V      +    +
Sbjct: 170 PFAYADLSEIIQRAGSANALVVVLDHVTDEGNFGAIVRSAEVVGAAGVVIANARAARVGV 229

Query: 61  --ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
                +AG+   + +     +  A+  LK  G     +          E        ++M
Sbjct: 230 GAYKTSAGAVLHLPIAQVSNLPRALEELKAAGFWTCGSTEHA-TQSVWEAPMGGRLALVM 288

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           G E +GI++  L   D    +P  G V+SLNV+ A+ ++ YE  R+ Q A
Sbjct: 289 GSEGSGISRLMLEKCDFTCKLPQFGQVESLNVAQATTVMCYEWLRRTQEA 338


>UniRef50_A4XKC2 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Clostridia
           RepID=A4XKC2_CALS8
          Length = 271

 Score =  190 bits (484), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 44/170 (25%), Positives = 74/170 (43%), Gaps = 8/170 (4%)

Query: 2   NPTRYARICEMLAR-----RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
            P      C    +     ++ +  V ++ V  P N+  IIR ADA G   V  V     
Sbjct: 103 TPQGVLAECSFFDKELDVLKKHNRVVVIDSVQDPGNLGTIIRCADAFGFECVITVNGTVD 162

Query: 57  MRT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
           +    +  +A GS   V V   R   + +  L  +G  +  T    + VD  ++      
Sbjct: 163 VYNPKVVRSAMGSMFHVDVVRERKKEEVLEALNKRGFALYVTTPYGD-VDISKLSVDDRF 221

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            I++G E  G+    L  A + + I M G  +SLN +VA+A++LYE +++
Sbjct: 222 AIVIGNESKGVDVAFLENATKKVKISMPGKAESLNSAVAAAIVLYELRKK 271


>UniRef50_C7MMG3 rRNA methylase, putative, group 3 n=1 Tax=Cryptobacterium curtum
           DSM 15641 RepID=C7MMG3_CRYCD
          Length = 300

 Score =  190 bits (484), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 42/184 (22%), Positives = 80/184 (43%), Gaps = 19/184 (10%)

Query: 3   PTRYARICEMLARRQP----------------DLTVCMEQVHKPHNVSAIIRTADAVGVH 46
           P  YA + +++AR                    L + ++ +    N+ AI R+A++VG  
Sbjct: 76  PFAYASLDDIIARGNDQAVSLAVSHSSSAAPCALIIVLDHITDAGNLGAIARSAESVGAA 135

Query: 47  EVHAVWPGSR--MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVD 104
            +      S     +   ++AG+ S + V     +  A+A LK +G  +           
Sbjct: 136 GIIIPNKRSAYVTASTYKSSAGAISHIPVAQVANLQQALARLKNEGYWVAGASEKAEG-G 194

Query: 105 FREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
             + + T   C++MG E TG+ +      D  + +P  G+V SLNV+ ++ + +YE  RQ
Sbjct: 195 IWDANLTGNVCLVMGNENTGLARLTQEACDFFVSLPQRGVVSSLNVAQSATVCMYEWLRQ 254

Query: 165 RQNA 168
            + +
Sbjct: 255 NRLS 258


>UniRef50_B2GD96 rRNA methylase n=26 Tax=Bacilli RepID=B2GD96_LACF3
          Length = 259

 Score =  190 bits (484), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 40/169 (23%), Positives = 76/169 (44%), Gaps = 8/169 (4%)

Query: 1   MNPTRYARICEMLARRQ-----PDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS 55
           + P     + ++    Q         + +++V  P NV  ++RTADA G   V A    +
Sbjct: 87  VTPQGIMVVADLPDLHQVATDLSGAWLFLDRVQDPGNVGTMVRTADAAGFAGVVAGDGSA 146

Query: 56  RM--RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
            +    +  +  GS   + +     +      +K  G  +  T L+  A DFR +     
Sbjct: 147 DLFSPKVVRSMQGSQFHLALYE-GDLKKWFEDVKQAGYPVYGTQLNPAAKDFRIVTPQGG 205

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
             ++MG E  G+++E L     ++ IPM G  +SLNV+V++ ++++E  
Sbjct: 206 FALVMGNEGRGMSEELLKQTTANLYIPMRGQAESLNVAVSAGILMFELA 254


>UniRef50_A7VXH5 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VXH5_9CLOT
          Length = 270

 Score =  190 bits (483), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 40/172 (23%), Positives = 80/172 (46%), Gaps = 9/172 (5%)

Query: 1   MNPTRYARICEMLAR-------RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP 53
           + P     +C ML +             + +E +  P N+  ++RTA+A+G+  V     
Sbjct: 92  VTPQGIFCVCAMLDKTDCLDKMDASGQLLGLEDIQDPSNLGTVLRTAEALGIGGVILTRG 151

Query: 54  GSRMR--TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYT 111
              +    +   + G+   + +    T+  AV  L+ +G   +A      A    ++ ++
Sbjct: 152 CCDIYSPKVLRGSMGAVFRLPMALVETMPPAVNALEQKGFVTMAAVPDREAEPITQVLFS 211

Query: 112 RPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
            P+ +L+G E  G+  E +    + + IPM+G  +SLN SVA++L+++E  R
Sbjct: 212 SPSIVLVGNEGNGLKPETIRACQRRVTIPMLGRAESLNASVAASLLMWEMMR 263


>UniRef50_C0W229 tRNA/rRNA methyltransferase n=2 Tax=Actinomyces RepID=C0W229_9ACTO
          Length = 322

 Score =  190 bits (483), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 49/175 (28%), Positives = 80/175 (45%), Gaps = 8/175 (4%)

Query: 1   MNPTRYARICEMLAR----RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           +    Y    ++L R     Q  L V ++QV  PHN+ A++R+  A G+  V      S 
Sbjct: 149 VPEYDYCSAQDLLERTKENAQIPLIVALDQVTDPHNLGAVLRSGGAFGITGVLISERRSA 208

Query: 57  MRTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDY-TRP 113
               A    +AG+ + V V     +  A+  LK  G  ++        V  R++D  T P
Sbjct: 209 SVNAAAWKVSAGAAARVPVARETNLVRALGELKEAGCFVVGLD-GGGDVSLRDLDLATGP 267

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
             ++ G E  G+++      DQ + IP+   V+SLN +VA+ + LYE   +R  A
Sbjct: 268 LVVVTGAEGKGLSRLVRETCDQIVSIPISSAVESLNAAVATGIALYEVASKRAEA 322


>UniRef50_C7PMX4 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Chitinophaga
           pinensis DSM 2588 RepID=C7PMX4_CHIPD
          Length = 263

 Score =  189 bits (482), Expect = 5e-47,   Method: Composition-based stats.
 Identities = 40/167 (23%), Positives = 75/167 (44%), Gaps = 7/167 (4%)

Query: 5   RYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT- 59
            Y  + +++     + Q  L + ++ +    N+ AI R+A   G   +     G      
Sbjct: 96  NYLDLQDVISHVTEQGQTPLFLILDGITDVRNIGAIARSAVCCGAQAIIIPDRGIAALNE 155

Query: 60  -MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
               ++AG+   + V    ++  A+  L   G++++A+ +        +     P  ++M
Sbjct: 156 EAIKSSAGALETISVCRVNSLLKAIDTLHLNGIKVIASEMEAETK-LYDCQLQEPVAVIM 214

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           G E  G+    +  +D    IPM G  +S NVSVA+ +ILYEA +QR
Sbjct: 215 GSEDKGVFPALIKASDTLFHIPMAGNFESFNVSVAAGIILYEAMKQR 261


>UniRef50_Q6MA83 Putative rRNA methylase n=2 Tax=Chlamydiae/Verrucomicrobia group
           RepID=Q6MA83_PARUW
          Length = 265

 Score =  189 bits (481), Expect = 6e-47,   Method: Composition-based stats.
 Identities = 52/171 (30%), Positives = 89/171 (52%), Gaps = 7/171 (4%)

Query: 1   MNPTRYARICEM-LARRQP--DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM 57
           + P R+  + ++ L  ++P     V  E + KP N+  I+R++DAVG+  +      + +
Sbjct: 94  IAPQRHLTLDDLSLKTKKPMAPFFVVAEAIEKPGNLGTILRSSDAVGIDGLIVCDRCTDI 153

Query: 58  RT--MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
               +  A+ G+   V     R   D +  L  QG+ ILA        +F ++D T P  
Sbjct: 154 YNPNVVRASVGTLFTVPTVEARG-EDILLWLNKQGIDILAATPHAE-KEFTQVDLTSPVA 211

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           I +G E+ G+++  +  A   + IPM+G+  SLNV++A+ L+LYE  RQRQ
Sbjct: 212 IAVGTEQLGLSERWMKQATMQVRIPMMGVADSLNVAMATTLLLYEVLRQRQ 262


>UniRef50_D1PXH3 SpoU rRNA methylase n=1 Tax=Prevotella bergensis DSM 17361
           RepID=D1PXH3_9BACT
          Length = 269

 Score =  189 bits (481), Expect = 6e-47,   Method: Composition-based stats.
 Identities = 52/158 (32%), Positives = 81/158 (51%), Gaps = 4/158 (2%)

Query: 13  LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM--ASAAAGSNSW 70
           L   +  L V +E V KP N+ A++R+ADA     V    P + +       ++ G+   
Sbjct: 114 LDLPESPLIVVLESVEKPGNLGAVLRSADASKADAVIVCNPLTDLFNPNLIRSSIGAIFT 173

Query: 71  VQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEAL 130
           V      +    +  LK + ++IL   L D+A  + + D    T I+MG E TG+T    
Sbjct: 174 VPTVACSS-QACMNFLKERNIKILTAQLQDSA-PYYDSDMRGGTAIVMGTESTGLTDAWR 231

Query: 131 ALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
             AD  I IPM+G + SLNVSV++A++++EA RQR   
Sbjct: 232 KAADAHIRIPMLGQLDSLNVSVSAAILMFEAVRQRSFK 269


>UniRef50_C5WEU6 23S rRNA methyltransferase n=2 Tax=Firmicutes RepID=C5WEU6_STRDG
          Length = 245

 Score =  189 bits (481), Expect = 7e-47,   Method: Composition-based stats.
 Identities = 44/164 (26%), Positives = 74/164 (45%), Gaps = 7/164 (4%)

Query: 2   NPTRYARICEM----LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM 57
           +P       +M             + +E V  P N+  IIRTADA G   V      + +
Sbjct: 80  SPQGIIAEVDMPQLAFPTDYQGKYLILEDVQDPGNLGTIIRTADAAGFDGVFLSEKSADV 139

Query: 58  RTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
                  +  GS+  + +     I      ++     +LAT LS  +VD++ + +     
Sbjct: 140 YNSKTLRSMQGSHFHLPIWR-TDIYKICREMQEHNTPVLATTLSKVSVDYKTVPHQESFA 198

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILY 159
           ++MG E  GI+ E   LADQ + I M G  +SLNV+VA+ ++++
Sbjct: 199 LVMGNEGQGISAEMTTLADQLVHITMPGQAESLNVAVAAGILIF 242


>UniRef50_D0JB44 tRNA/rRNA methyltransferase n=2 Tax=Blattabacterium
           RepID=D0JB44_BLASB
          Length = 253

 Score =  189 bits (481), Expect = 7e-47,   Method: Composition-based stats.
 Identities = 45/175 (25%), Positives = 89/175 (50%), Gaps = 7/175 (4%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++P    +I ++L     + +  L V ++++    N  +IIRT+  VG   +      + 
Sbjct: 76  LSPIETYQIKDLLPVFYEKGKNPLLVILDRITDVRNFGSIIRTSACVGADAIIIPKKYTA 135

Query: 57  M--RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
           M        ++G+   V +   + I + +  L   G++I++     + + +  ID++ PT
Sbjct: 136 MIGSDSIKTSSGALFKVPICQEKNIKNTIEFLMNSGLKIVSAT-EKSNIYWYNIDFSGPT 194

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
            +++G E+ GI+ + L ++ +   IP I  + SLNVSVA  +ILYE  RQR++  
Sbjct: 195 ALILGNEEKGISPKYLEISCEKAKIPAIKGISSLNVSVACGVILYEVFRQRKSQS 249


>UniRef50_A0LPE7 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Syntrophobacter
           fumaroxidans MPOB RepID=A0LPE7_SYNFM
          Length = 252

 Score =  189 bits (481), Expect = 7e-47,   Method: Composition-based stats.
 Identities = 44/169 (26%), Positives = 77/169 (45%), Gaps = 5/169 (2%)

Query: 1   MNPTRYARICEMLARRQPDL--TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR-- 56
           M    YA +  +L +   +    V ++ +  P N+ A++R+A  +G   V      S   
Sbjct: 81  MREFPYAALEALLEKPTGEREPLVILDCLQDPQNLGAMLRSACFLGARGVIVPRDRSARV 140

Query: 57  MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
             T+   AAG+ +++ V     +  A+  LK  G+ I     +  A    + D T P  +
Sbjct: 141 TSTVIRIAAGATAYLPVIQVNNLVRALEQLKECGLWIFGLD-AQAAQTIYDADLTVPLGL 199

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           ++G E+ G+        D  + IP  G +QSLN + + A+ L E QR+R
Sbjct: 200 VVGNEQKGLRPLVARACDAMVRIPEHGPLQSLNAATSGAIALAEVQRRR 248


>UniRef50_A8S2F6 Putative uncharacterized protein n=8 Tax=Clostridiales
           RepID=A8S2F6_9CLOT
          Length = 270

 Score =  189 bits (480), Expect = 9e-47,   Method: Composition-based stats.
 Identities = 41/171 (23%), Positives = 83/171 (48%), Gaps = 6/171 (3%)

Query: 4   TRYARICEMLARRQPDL---TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT- 59
            +   + +++           + +E +  P N+  IIR  +  G+  +      + +   
Sbjct: 95  QKRYTMDDIVKPAPDGRSLAIMVLETIQDPGNLGTIIRAGEGAGITGIVMNHDTADIYNP 154

Query: 60  -MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
            +  +  GS   +       + DA   +K +G+++ A HL     ++ + DYT     L+
Sbjct: 155 KVIRSTMGSIFRMPFVYADDLQDACLLMKNRGVRLFAAHL-KGMNNYDQEDYTDNVGFLI 213

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
           G E  G+T+E  +LAD  + IPM G V+SLN ++A++++++E  RQR++  
Sbjct: 214 GNEANGLTEETTSLADCLVKIPMEGKVESLNAAIAASVLMFETARQRRSCS 264


>UniRef50_Q2GL62 RNA methyltransferase, TrmH family, group 3 n=5 Tax=Anaplasma
           RepID=Q2GL62_ANAPZ
          Length = 258

 Score =  189 bits (480), Expect = 9e-47,   Method: Composition-based stats.
 Identities = 37/160 (23%), Positives = 66/160 (41%), Gaps = 3/160 (1%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MAS 62
           R   I            + +++V   HNV A++RTA    V  V      S   +  MA 
Sbjct: 94  RIEDIVAQTEAAPTSTILVLDEVTDVHNVGAVLRTAACFNVDAVVLTEHNSPSESCGMAK 153

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
           A++G+   V V     +   + +LK +         S       +++++    +++G E 
Sbjct: 154 ASSGAIDIVPVVCIGNLVKTLEYLKQKNYWCYGFDASGG-TCLHQVEFSERRVVILGAEG 212

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
            G+        D  + IPM   ++SLNVS A+A+ +Y   
Sbjct: 213 KGMRHLTKKHCDHLVKIPMSEKMESLNVSNAAAIAMYSVF 252


>UniRef50_B1ZVF9 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Opitutaceae
           RepID=B1ZVF9_OPITP
          Length = 296

 Score =  189 bits (480), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 45/152 (29%), Positives = 78/152 (51%), Gaps = 4/152 (2%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSNSWVQV 73
           ++    + +E + KP N+  I+R+ADA G   V    P +      +  A+ G    V +
Sbjct: 145 QRAPFILVVEAIEKPGNLGTILRSADAAGCDAVIVCDPVTDIFNPNVVRASTGVLFSVPL 204

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALA 133
               +    +A L+ QG++ +AT  +   + + + D   P  I+MG E+ G+++  L   
Sbjct: 205 VVAES-APVLAWLRAQGVRTIATTPAAEKL-YTDADLRGPLAIVMGSEQYGLSEFWLKNC 262

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           D  + IPM G   SLNV++A+ + L+EA RQR
Sbjct: 263 DLPVRIPMAGQADSLNVAMATIITLFEAVRQR 294


>UniRef50_Q1IND6 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Candidatus Koribacter
           versatilis Ellin345 RepID=Q1IND6_ACIBL
          Length = 285

 Score =  188 bits (479), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 49/176 (27%), Positives = 85/176 (48%), Gaps = 11/176 (6%)

Query: 2   NPTRYARICEM-------LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG 54
           +P   A + ++       L R +  + + +  V  P N+  I+R+A+A G   V      
Sbjct: 112 SPQGVAALVKLKTFKLEDLLRAENPMLLGVAGVQDPGNLGTILRSAEAFGATGVLIGDKT 171

Query: 55  SRM--RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR 112
           +      +   ++GS   + V        A+  L+ +G+QILAT          E+D+T 
Sbjct: 172 ASPWNPKVIRGSSGSVFRLPVVKVE-WPAALEQLRAKGVQILATSSHKGE-PLPEVDFTG 229

Query: 113 PTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNA 168
           PT +L+G E  G+ ++ LA  D  + IP    V+SLN  +A+++++YEA RQR   
Sbjct: 230 PTIVLIGGEGAGVPRDVLASVDGTLAIPHSPKVESLNAGIAASIVMYEAARQRNTQ 285


>UniRef50_C4V3B4 TrmH family rRNA methyltransferase n=2 Tax=Selenomonas
           RepID=C4V3B4_9FIRM
          Length = 276

 Score =  188 bits (479), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 49/154 (31%), Positives = 78/154 (50%), Gaps = 3/154 (1%)

Query: 19  DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR--TMASAAAGSNSWVQVKTH 76
            L + +++V  P NV  I+RTADA G   V  +   + +    +  AA GS  ++   T 
Sbjct: 124 PLYLALDRVQDPGNVGTILRTADAAGASGVILLRGCADVYGSKVVRAAMGSLFYLPFVTG 183

Query: 77  RTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQD 136
               D V   K   +   A     + V     + +RP+ +++G E  G+++  L  A Q 
Sbjct: 184 VDEEDLVRFAKENVLCFYAAACDTDGVTHFAAELSRPSLVVLGNEANGVSERLLR-AGQH 242

Query: 137 IIIPMIGMVQSLNVSVASALILYEAQRQRQNAGM 170
           + +PM G  +SLNV+ A+  ILYEA RQR+ AG+
Sbjct: 243 LYVPMCGRAESLNVAAAATAILYEAIRQRKYAGI 276


>UniRef50_B9KYY7 RNA methyltransferase, TrmH family, group 3 n=4 Tax=Chloroflexi
           RepID=B9KYY7_THERP
          Length = 261

 Score =  188 bits (479), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 46/165 (27%), Positives = 80/165 (48%), Gaps = 2/165 (1%)

Query: 2   NPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRT 59
           +P  Y     +L      + + ++ +  P N++ ++RTA+A GV  V      +      
Sbjct: 83  SPYPYVDFATLLDPAPESIVLLLDHLQDPQNIATLLRTAEAAGVRGVVLPERRAAGITPA 142

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
           + +A+AG+   +Q+     +  AV  L+  G  I+A     NA          P  +L+G
Sbjct: 143 VVNASAGAVEHLQITLVTNLARAVDTLREHGYWIVALEPGPNAQSLFRAPLPLPLVLLVG 202

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            E  G++   L  AD  +IIPM+G ++SLN +VA ++ LYE  R+
Sbjct: 203 AEGHGLSPVLLKRADVQVIIPMLGQIESLNAAVAGSIALYEIVRR 247


>UniRef50_B0PD55 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
           DSM 17241 RepID=B0PD55_9FIRM
          Length = 264

 Score =  188 bits (479), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 42/172 (24%), Positives = 74/172 (43%), Gaps = 9/172 (5%)

Query: 1   MNPTRYARICEMLARRQPDL-------TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP 53
           ++P     +  ML  R   +        + +  +  P NV  I+RTA A G   V     
Sbjct: 93  VSPQGVFGVFMMLDNRTQPVKIGSNGKYLLLSSLQDPGNVGTILRTAAAFGTDGVILSAD 152

Query: 54  GSRMR--TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYT 111
              +    +  A+ G     +      +  ++A L+  G+ + A   ++ +V  R+I   
Sbjct: 153 CPDLYAPKVLRASMGGVFRARACVSDDLSASIAALRAAGVPVWAAMPAEGSVSLRDISLH 212

Query: 112 RPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
               +++G E  GI  E  AL D  + IPM    +SLN ++A+ +IL+E  R
Sbjct: 213 GGGAVVVGNEGGGIAPELAALCDGALTIPMEPGCESLNAAMAAGVILWEMYR 264


>UniRef50_B9E768 rRNA methyltransferase homolog n=1 Tax=Macrococcus caseolyticus
           JCSC5402 RepID=B9E768_MACCJ
          Length = 246

 Score =  188 bits (478), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 43/166 (25%), Positives = 76/166 (45%), Gaps = 9/166 (5%)

Query: 2   NPTRYARICEMLARRQPDL--TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT 59
            P     +C M   +  +L   + ++++  P NV  IIRTADA G+  V        +  
Sbjct: 86  APQGIYAVCNMKDGKDAELNRVIYLDRIQDPGNVGTIIRTADAAGLDAVIIAKGTVDIYN 145

Query: 60  --MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCIL 117
             +  A+ GS   + V       D           I  T L + A D++E+  +    I+
Sbjct: 146 DKVLRASQGSVFHIPVIEM----DFDEVSSKFNGTIYGTSL-EEARDYKEVIPSDNFMIV 200

Query: 118 MGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
           +G E  G+  E L+  D+++ IP+ G  +SLNV+V + +++Y   +
Sbjct: 201 LGNEGQGVNPEILSATDENLYIPIYGRAESLNVAVCAGILMYHFVK 246


>UniRef50_D0LZ96 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Haliangium
           ochraceum DSM 14365 RepID=D0LZ96_HALO1
          Length = 267

 Score =  188 bits (478), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 48/163 (29%), Positives = 78/163 (47%), Gaps = 5/163 (3%)

Query: 4   TRYARICEMLA--RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT-- 59
             YA + +++A  R++P L V ++ V  PHN+ AI+R+A  +G   V      +   +  
Sbjct: 93  FEYAALEDLIAAPRQRPALFVALDSVTDPHNLGAIVRSAHVLGADGVILPKDRAAQVSGV 152

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
           +   +AG+   + +     +  A+  LK   + I      + A      D T   C+++G
Sbjct: 153 VTKVSAGATEQIAIAQVTNLARALEQLKQAEVWIAGLAAGEGATSLPAFDATGALCLVLG 212

Query: 120 QEKTGITQEALALADQDIIIPMIG-MVQSLNVSVASALILYEA 161
            E TG+        D  I IPM+G  V SLNVSVA+ + LYE 
Sbjct: 213 AEGTGLRPLVARTCDFLIEIPMLGAGVGSLNVSVAAGVALYEV 255


>UniRef50_A4E9D9 Putative uncharacterized protein n=1 Tax=Collinsella aerofaciens
           ATCC 25986 RepID=A4E9D9_9ACTN
          Length = 302

 Score =  188 bits (478), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 45/176 (25%), Positives = 75/176 (42%), Gaps = 7/176 (3%)

Query: 4   TRYARICEMLAR--RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM- 60
             YA + ++L R    P L V ++ V    N  AI+R+A+ VG   V      +   T+ 
Sbjct: 130 FPYADVADILDRAGDGPALVVVLDHVTDDGNFGAIVRSAEVVGAAGVIIANKRAAGVTVG 189

Query: 61  -ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
               +AG+   + +     I  A+  LK  G  +             +  +     ++MG
Sbjct: 190 SYKTSAGAVMHLPIAQVPNIARALDDLKAAGFWVSGASERAEG-SCWDAPFEGRVALVMG 248

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLREN 175
            E  GI++  L   D    +P  GM +SLNV+ A+  + +E  R  +NAG  + E 
Sbjct: 249 SEGDGISRLVLEKCDFLTKLPQRGMTESLNVAQATTALCFEWLR--RNAGELMGEE 302


>UniRef50_B0MRI6 Putative uncharacterized protein n=1 Tax=Eubacterium siraeum DSM
           15702 RepID=B0MRI6_9FIRM
          Length = 262

 Score =  188 bits (478), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 37/168 (22%), Positives = 73/168 (43%), Gaps = 4/168 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--R 58
           +      +I  +         + +E +    N+  IIR+ DA  +  V      + +   
Sbjct: 97  ITVRHLDKILNLSTIDSSRQFIILENLQDMGNIGTIIRSCDAFSIDGVILAGDCADVFAP 156

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
               +A GS   + +       +A+  L+  G  + +  LSD +V   E    + T +++
Sbjct: 157 KTVRSAMGSLFRLPIY-CCDTEEAITLLQKGGFTVYSAELSDRSVRLGEEKLPQKTAVVI 215

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
           G E  G++     L D+ + IP+    +SLN SVA+++I +E  + R+
Sbjct: 216 GNEGNGVSDTVKKLCDKSLFIPIS-SAESLNASVAASVIAWEMSKVRE 262


>UniRef50_B7C827 Putative uncharacterized protein n=1 Tax=Eubacterium biforme DSM
           3989 RepID=B7C827_9FIRM
          Length = 244

 Score =  187 bits (477), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 33/141 (23%), Positives = 75/141 (53%), Gaps = 4/141 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMAS--AAAGSNSWVQVKTHRT 78
            + ++ V  P NV  I+RTA + G+  ++     + +    +  ++ G+  ++ V     
Sbjct: 99  ILLLDNVQDPGNVGTILRTAHSFGIDCIYMSKGCADIYNPKTIQSSQGALFYIPVIQ-TD 157

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           + + +  L+ + +++ AT L D   D ++I  ++   IL+G E  G+ +E + L++  + 
Sbjct: 158 LVEEIKKLQERNIEVYATALHDKHKDLQDIKPSKKYAILVGNEGQGVRKELIDLSNHIVK 217

Query: 139 IPMIGMVQSLNVSVASALILY 159
           I M    +SLNV++A+++ +Y
Sbjct: 218 IEME-TFESLNVAIATSICMY 237


>UniRef50_Q112U6 tRNA/rRNA methyltransferase (SpoU) n=2 Tax=Oscillatoriales
           RepID=Q112U6_TRIEI
          Length = 234

 Score =  187 bits (477), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 55/211 (26%), Positives = 96/211 (45%), Gaps = 9/211 (4%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           + P R  +I  +L +R  D+TV +E +++PHN SA++R+ D+ GV +VH V   +     
Sbjct: 17  ITPARREKILSVLQQRTRDITVILEDIYQPHNASAVLRSCDSFGVQDVHIVENKNIFTIT 76

Query: 61  ASAAAGSNSWVQVKTHR-----TIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
            S   GS+ W+ +  +         + +  LK +G  I AT      +   E+       
Sbjct: 77  QSVTIGSDRWLTLYRYNEQSINNTEECLKRLKNEGYVIAATTPYKEHITIEELSVNTKVA 136

Query: 116 ILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLREN 175
           ++ G E  G+++ A   AD  + IPM+G  +S N+SV++AL LY    + +        N
Sbjct: 137 LMFGSEINGLSEYAKNNADVSVKIPMVGFSESFNISVSAALCLYNLMSRLKKEH----NN 192

Query: 176 SMLPEAEQQRLLFEGGYPVLAKVAKRKGLPY 206
             L E E+  L        +      +   +
Sbjct: 193 WKLTETEKLDLELNWLQKSIKGGELIEKKFF 223


>UniRef50_Q6MNP1 Putative RNA methylase n=1 Tax=Bdellovibrio bacteriovorus
           RepID=Q6MNP1_BDEBA
          Length = 238

 Score =  187 bits (476), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 68/194 (35%), Positives = 101/194 (52%), Gaps = 3/194 (1%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           +   R  +I +++A R  D  V +E ++   N+SA++R+A+ +G    H +    + +  
Sbjct: 29  LTDERRQKIEKVVALRNFDTAVVLEGIYDRGNISAVMRSAEGLGFGNFHVIETQEKFKEA 88

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
                G++ WV+VK  +   D V  LK QG +I  THL  NA    EID++  T +++G 
Sbjct: 89  NRVTQGADKWVEVKKWKKTADCVKALKNQGYKIYVTHLDANAKPLHEIDFSGKTALVLGN 148

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLPE 180
           E+ G+T E +A ADQ IIIPM G VQS N+SVA AL LY   + R         N+ L E
Sbjct: 149 ERDGVTPEMIAAADQTIIIPMTGFVQSFNISVAGALGLYHISQDRLK---RRGTNASLTE 205

Query: 181 AEQQRLLFEGGYPV 194
            EQ  L        
Sbjct: 206 EEQGILRAHYYMRT 219


>UniRef50_B3RWG3 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
           RepID=B3RWG3_TRIAD
          Length = 246

 Score =  187 bits (476), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 59/195 (30%), Positives = 96/195 (49%), Gaps = 4/195 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVH-AVWPGSRMRT 59
               R  ++   +  R   + V +E +    N  AI RT DA+G    H    P  R++T
Sbjct: 50  FTKERLDKMTNAVKNRTRSIAVVLEGITNEGNEQAIYRTMDALGFQTAHRIPSPLYRLKT 109

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
                AG+  W+ +++ ++  + ++ LK  G +ILAT   +        D++  T +++G
Sbjct: 110 CGRTDAGAMKWIDIESWKSTEECISQLKSCGYKILATSSENKTKTLDSFDFSNKTAVVLG 169

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E+ GI++EA+ L D    I M+G V+S NVSVA+A+ILY   + R     Y   +  L 
Sbjct: 170 SEQEGISKEAMNLVDNVFRISMVGFVESYNVSVAAAIILYHIYQDRIRKLGY---HGDLT 226

Query: 180 EAEQQRLLFEGGYPV 194
           EAEQ  LL +     
Sbjct: 227 EAEQDDLLLQYMLKE 241


>UniRef50_B7GPD2 RNA methyltransferase, TrmH family, group 3 n=4 Tax=Bifidobacterium
           longum RepID=B7GPD2_BIFLI
          Length = 333

 Score =  187 bits (476), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 42/189 (22%), Positives = 79/189 (41%), Gaps = 20/189 (10%)

Query: 1   MNPTRYARICEMLARRQ------------------PDLTVCMEQVHKPHNVSAIIRTADA 42
           ++P +Y+ + E+  R +                    L + ++ V  P N+ A+IR+A A
Sbjct: 143 VDPFQYSSLNELADRAEKKAKAMEAANSAAARIAARPLFIALDGVTDPQNLGAVIRSAAA 202

Query: 43  VGVHEVHAVWPGSRMRTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSD 100
            G + V      S     A    +AG+ + + V     +  A+  LK +G  ++      
Sbjct: 203 FGANGVILPERRSASVNAAAWKVSAGAAAHMPVARVVNLTKALEGLKERGYYVVGLDGGG 262

Query: 101 NAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYE 160
           + +       + P  +++G E +G+ +      D    IP+   V+SLN SVA+ + LY 
Sbjct: 263 DKLVGETGFESDPLVVVLGSEGSGLGRLVRETCDAIAGIPISSSVESLNASVAAGISLYA 322

Query: 161 AQRQRQNAG 169
               R+ A 
Sbjct: 323 VSNARRKAA 331


>UniRef50_O51468 Uncharacterized tRNA/rRNA methyltransferase BB_0516 n=21
           Tax=Borrelia RepID=Y516_BORBU
          Length = 228

 Score =  187 bits (476), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 37/162 (22%), Positives = 79/162 (48%), Gaps = 3/162 (1%)

Query: 5   RYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS--RMRTMAS 62
            +  + E   +++    + ++++  P N  AI+RTA+   +  V      S     T+  
Sbjct: 64  DFENLLETFKKKENAFILLLDEIEDPQNFGAILRTAEQFSIDLVITTQKRSAKDNSTVLR 123

Query: 63  AAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEK 122
            ++G++ +V+  T   I + +  LK  G  I    +    ++  +I+  +   +++G E 
Sbjct: 124 TSSGASQYVKKMTVTNINNTINLLKNYGFWIYTGDIKGQDINKIKIN-DKKIALILGNEG 182

Query: 123 TGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
            G+ +     +D  I IP  G + SLNVSV++ ++++E +RQ
Sbjct: 183 KGVHKLIKENSDFLIRIPTSGKIDSLNVSVSTGILIFEIKRQ 224


>UniRef50_B0MYM4 Putative uncharacterized protein n=1 Tax=Alistipes putredinis DSM
           17216 RepID=B0MYM4_9BACT
          Length = 228

 Score =  187 bits (475), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 55/209 (26%), Positives = 98/209 (46%), Gaps = 5/209 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTM 60
           M+  R   +   L  R   +T+  E  +   N SA++R  +A GV ++H +    +    
Sbjct: 23  MSEERRQVLQRTLDSRTRYMTILTENTYHAQNASALVRHCEAFGVQDIHTIETRCKFNPN 82

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR-PTCILMG 119
            +   G++ W+ +  HRT  +A+A LKG+G +I+AT            D    P  ++ G
Sbjct: 83  VNIVRGTDKWIDLHRHRTTAEAIADLKGRGYRIVATTPHREDKTPETFDVAASPFVLVFG 142

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E  GI+ E +A AD+ + IPM GMV+SLNVS ++A+++Y    + +        +  L 
Sbjct: 143 TEHAGISDEIVAAADEFLRIPMCGMVESLNVSASAAILIYMLSSRMRE----TVPDWRLT 198

Query: 180 EAEQQRLLFEGGYPVLAKVAKRKGLPYPH 208
             ++  +L+   +  +          YP 
Sbjct: 199 AGKRAEILYRWTFASVRDAEAILRRKYPE 227


>UniRef50_Q4A651 Putative tRNA/rRNA methyltransferase n=1 Tax=Mycoplasma synoviae 53
           RepID=Q4A651_MYCS5
          Length = 233

 Score =  187 bits (475), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 39/161 (24%), Positives = 78/161 (48%), Gaps = 3/161 (1%)

Query: 3   PTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVW-PGSR-MRTM 60
              Y+ I ++   + P + + ++ +   +N+ AIIR+A+A G+ ++       +     +
Sbjct: 68  DFTYSDINKIYESK-PKIVLVLDHIMDTYNLGAIIRSANAAGIKDIVMPKENCADITSNV 126

Query: 61  ASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQ 120
              ++G    +      ++   +  LK     I  + L  N+  +    Y  P   ++G 
Sbjct: 127 LKVSSGGFIGINFYKVSSLNAFLNKLKKHSYWIYGSMLDKNSTSYYSAKYNFPMAFILGN 186

Query: 121 EKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEA 161
           E+ GI++ AL   D+ I IP  G V+SLNVSVA+ ++L++ 
Sbjct: 187 EEKGISKSALVEVDEKIHIPQSGSVESLNVSVAAGILLFDI 227


>UniRef50_A8R7Q7 Putative uncharacterized protein n=1 Tax=Eubacterium dolichum DSM
           3991 RepID=A8R7Q7_9FIRM
          Length = 244

 Score =  187 bits (475), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 37/145 (25%), Positives = 70/145 (48%), Gaps = 5/145 (3%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR--TMASAAAGSNSWVQVKTHRT 78
            + ++ V  P NV  I+R+A + G   V      + +    +  +  G+   +QV     
Sbjct: 103 VILLDDVQDPGNVGTILRSAYSFGFDTVVLSKHCADVYSDKVIRSTQGALFHMQVIR-TD 161

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           +   +  LK + + ++ T L +NA     I+      +L G E  G+++E LA  D+ + 
Sbjct: 162 LSQIIDQLKEKKIPVIGTAL-ENASAMSTIEAVDRVALLFGNEGNGVSKELLAKCDETMY 220

Query: 139 IPMIGMVQSLNVSVASALILYEAQR 163
           I M    +SLNV+VA+ + +Y+ +R
Sbjct: 221 IEMH-AFESLNVAVAAGIAMYKFRR 244


>UniRef50_Q038C4 rRNA methylase n=8 Tax=Lactobacillus RepID=Q038C4_LACC3
          Length = 253

 Score =  186 bits (474), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 38/164 (23%), Positives = 79/164 (48%), Gaps = 7/164 (4%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--R 58
           + P R  ++ E L+ +     + ++ +  P NV  ++RTADA G+  V      +     
Sbjct: 93  VMPRRAEQLPEPLSGQ----FLLLDAIQDPGNVGTLVRTADAAGIQTVVFGNGTADAFGP 148

Query: 59  TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILM 118
            +  A  GS   V++ + + +   +  L   G+ +  + L++ A  +  I  +    +++
Sbjct: 149 KVLRAMQGSQFHVRIVSAK-LMPIIKALHRGGIPVYGSELNEKAKSYHSIQPSERFALIV 207

Query: 119 GQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
           G E  G+    L   D ++ IP+ G  +SLNV+VA+A++++   
Sbjct: 208 GNEGNGMDPVLLQNTDTNLYIPIRGKAESLNVAVAAAVMMFHLV 251


>UniRef50_Q7MTU3 RNA methyltransferase, TrmH family n=5 Tax=Bacteria
           RepID=Q7MTU3_PORGI
          Length = 249

 Score =  186 bits (474), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 45/176 (25%), Positives = 83/176 (47%), Gaps = 7/176 (3%)

Query: 1   MNPTRYARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
           ++   Y R+ +++       +    + ++ +    N  AI RTA+  GV  +     GS 
Sbjct: 74  LSAIEYTRLDQLMPMLYEEGKAPFLLLLDGITDVRNFGAIARTAECAGVDAIIIPERGSV 133

Query: 57  MR--TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
                    +AG+   + V    +I  A+  L+  G++I+A      A  + ++    P 
Sbjct: 134 SVGGDAIKTSAGALHRIPVCRVTSIPGAIRSLQEYGIRIVAAS-EKAADLYTDVPMKLPL 192

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGM 170
            I+MG E  G + + L +AD  + IP +G + SLNVSVA+ +++YE  RQ++    
Sbjct: 193 GIVMGAEDVGPSPDTLRMADGIVAIPQMGAIGSLNVSVAAGIVIYEVVRQQRLQSS 248


>UniRef50_Q03G93 rRNA methylase n=1 Tax=Pediococcus pentosaceus ATCC 25745
           RepID=Q03G93_PEDPA
          Length = 255

 Score =  186 bits (473), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 40/141 (28%), Positives = 73/141 (51%), Gaps = 3/141 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAGSNSWVQVKTHRT 78
            + ++ V  P N+  ++RTADA G   V      +         A  GS   +Q+K    
Sbjct: 112 WLVLDNVQDPGNIGTMVRTADAAGFTGVVFGDGTADFYNPKILRAMQGSQYHLQLKRL-N 170

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           +   + + K QG  I  + L +NA D+R+ID      ++MG E  G+++  + + D ++ 
Sbjct: 171 LEKWIRNCKDQGSVIFGSILDENARDYRKIDVPDQFSLIMGNEGNGMSERLIEMTDMNLY 230

Query: 139 IPMIGMVQSLNVSVASALILY 159
           IP+ G  +SLNV+VA+ ++++
Sbjct: 231 IPIKGSAESLNVAVAAGVLMF 251


>UniRef50_Q1G9C5 TRNA/rRNA methyltransferase n=28 Tax=Lactobacillus
           RepID=Q1G9C5_LACDA
          Length = 260

 Score =  186 bits (473), Expect = 6e-46,   Method: Composition-based stats.
 Identities = 40/144 (27%), Positives = 67/144 (46%), Gaps = 3/144 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAGSNSWVQVKTHRT 78
            V ++ +  P NV  IIRTADA G   V        +       +  GS   + +     
Sbjct: 118 WVLLDDLADPGNVGTIIRTADAAGFDGVILSNKTVDLYNPKVQRSMQGSQFHLNLIK-AD 176

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           + DA+A LK   + + A+ L   A    +        +++G E  G++ E  ALAD+ + 
Sbjct: 177 LPDAIASLKAADIPVYASLLDPAAKQLGDFAPVAQVALIIGNEAHGVSPEIEALADEKLY 236

Query: 139 IPMIGMVQSLNVSVASALILYEAQ 162
           IP+ G  +SLN +VA+ +++Y   
Sbjct: 237 IPIKGRAESLNAAVAAGIMIYHFS 260


>UniRef50_B9Y9V6 Putative uncharacterized protein n=1 Tax=Holdemania filiformis DSM
           12042 RepID=B9Y9V6_9FIRM
          Length = 244

 Score =  186 bits (473), Expect = 6e-46,   Method: Composition-based stats.
 Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 5/145 (3%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTHRT 78
           TV ++ V  P NV  IIRTA A G  +V      + +       +  G+   + +     
Sbjct: 101 TVVLDGVQDPGNVGTIIRTAVAFGFDQVLLSPDCADVYNEKCVRSTQGALFHIAISR-TE 159

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
           +  A+  LK  G+ ++ T L   A    E+  +    +++G E  GI    L + DQ  +
Sbjct: 160 LIPALNELKELGVTVIGTAL-QGAQPLSELPVSENIAVVLGNEGQGIRPATLDICDQRAL 218

Query: 139 IPMIGMVQSLNVSVASALILYEAQR 163
           I M    +SLNV+VA+ + LY  +R
Sbjct: 219 IEMS-SFESLNVAVAAGICLYRYRR 242


>UniRef50_C9XLS4 Putative RNA methylase n=9 Tax=Clostridium RepID=C9XLS4_CLODC
          Length = 265

 Score =  185 bits (472), Expect = 8e-46,   Method: Composition-based stats.
 Identities = 38/162 (23%), Positives = 85/162 (52%), Gaps = 5/162 (3%)

Query: 4   TRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MA 61
            +  ++ E + ++     + ++++  P N+  IIRTAD+ GV  + A+     +    + 
Sbjct: 104 FKKKKLSESINKKDK-FVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPKVI 162

Query: 62  SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQE 121
            +  GS   + +    +  + V  LK     I++++L+     + +IDY     +++G E
Sbjct: 163 RSTMGSIFDMNII-DASQDETVDMLKSLDFNIVSSYLNTE-NFYDKIDYGSKVALVIGNE 220

Query: 122 KTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
             GI +E ++ +D  + IP+ G  +SLN +++SA+++YE ++
Sbjct: 221 ANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKK 262


>UniRef50_A6P2D0 Putative uncharacterized protein n=1 Tax=Bacteroides capillosus
           ATCC 29799 RepID=A6P2D0_9BACE
          Length = 252

 Score =  185 bits (471), Expect = 9e-46,   Method: Composition-based stats.
 Identities = 45/169 (26%), Positives = 76/169 (44%), Gaps = 9/169 (5%)

Query: 2   NPTRYARICEML-----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR 56
            P     +C         +      + ++ V  P N+  I RTADA G   +  V   + 
Sbjct: 86  TPQGLLAVCRNPGLTPPDKLTGGRYLVLDGVQDPGNLGTIWRTADAFGADGLLLVNGCAD 145

Query: 57  MRTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPT 114
             +     A  G+   +       +    A L G  + + AT L ++ VD R++D  +  
Sbjct: 146 PWSPKTIRATMGACFRLP-AWETDLETVRALLDGADIPLYATALREDTVDVRDVDL-KRA 203

Query: 115 CILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
            +++G E  GI+ EALAL  + I IPM    +SLN ++A+ ++L+E  R
Sbjct: 204 AVVIGSEGRGISDEALALCRRTIKIPMRARCESLNAAMAAGVVLWEMCR 252


>UniRef50_C0BGA8 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Flavobacteria
           bacterium MS024-2A RepID=C0BGA8_9BACT
          Length = 244

 Score =  185 bits (471), Expect = 9e-46,   Method: Composition-based stats.
 Identities = 47/160 (29%), Positives = 72/160 (45%), Gaps = 3/160 (1%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAG 66
           I  +L  ++  + V ++ V    N  AI+R+A A GV  V     GS      +   +AG
Sbjct: 86  IESVLKEKENPVFVLLDGVTDTRNFGAILRSAAATGVDAVFISSTGSAPLNGDVVKTSAG 145

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
               V +   + + D V +LK   +  L      +     + D   P  ++ G E  GI+
Sbjct: 146 GAFKVPISKVQHLKDVVYYLKAHDIPTLGIT-EKSTETLYDSDLKGPLALVFGAEDVGIS 204

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQ 166
              L + D    +PM   V SLNVSVA A++ YE  RQR+
Sbjct: 205 NGLLKILDHKAKLPMTEAVDSLNVSVACAVVFYETIRQRR 244


>UniRef50_C0W457 tRNA/rRNA methyltransferase n=2 Tax=Actinomycetaceae
           RepID=C0W457_9ACTO
          Length = 330

 Score =  185 bits (471), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 43/173 (24%), Positives = 73/173 (42%), Gaps = 8/173 (4%)

Query: 4   TRYARICEMLAR----RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--M 57
             Y    ++L R        L V ++QV  PHN+ A++R+  A G   V      S    
Sbjct: 157 YGYTSALDLLDRARAVGHTPLLVALDQVTDPHNLGAVLRSTGAFGGDGVIIPERRSVGVN 216

Query: 58  RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR-PTCI 116
            T+   +AG+ + V V     +   +  LK +G  ++            ++     P  +
Sbjct: 217 ATVWKVSAGAAARVPVARETNLVRTLETLKKEGCFVVGLD-GGGETLMEDLSLADSPLVL 275

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
           + G E  G+++      D    IP+   V+SLN +VA+ + LYE  R R+ A 
Sbjct: 276 VTGAEGAGLSRLVRETCDVIASIPISQTVESLNAAVATGISLYEVDRLRRAAA 328


>UniRef50_C6VPS4 rRNA methylase n=8 Tax=Lactobacillales RepID=C6VPS4_LACPJ
          Length = 257

 Score =  185 bits (470), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 44/172 (25%), Positives = 80/172 (46%), Gaps = 10/172 (5%)

Query: 1   MNPTRY-------ARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWP 53
           + P          A I ++         + ++ V  P N+  ++RTADA G   V     
Sbjct: 87  VTPQGVFALATLPAAIEDLSQLDLTRPWLLLDNVQDPGNIGTMVRTADAAGFAGVAFGTG 146

Query: 54  GSRM--RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYT 111
              +    +  A  GS   +Q+ +   +   V  L+ QG  +  + L+  A  + +ID  
Sbjct: 147 TVDIHQPKVERAMQGSQFHLQLIS-TDLDKLVDQLQAQGSPVYGSELNPQAARYLDIDAP 205

Query: 112 RPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQR 163
               ++MG E  G+++E LA  DQ++ IP+ G  +SLNV+VA+ ++++   R
Sbjct: 206 ASFGLIMGNEGNGMSRELLARTDQNLYIPIKGQAESLNVAVAAGVLMFGLYR 257


>UniRef50_D2RCJ3 RNA methyltransferase, TrmH family, group 3 n=14
           Tax=Actinobacteridae RepID=D2RCJ3_GARVA
          Length = 331

 Score =  185 bits (470), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 43/190 (22%), Positives = 79/190 (41%), Gaps = 20/190 (10%)

Query: 1   MNPTRYARICEMLARRQ------------------PDLTVCMEQVHKPHNVSAIIRTADA 42
           + P +Y  + E++ R +                    L + ++ V  P N+ A+IR+A A
Sbjct: 139 VQPYQYHSLQELVERAEKKARAMEAADSDSARINARPLFIALDGVTDPQNLGAVIRSAAA 198

Query: 43  VGVHEVHAVWPGSRMRTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSD 100
            G + V      S   T A    +AG+ + + V     +  A+  L+ +G   +      
Sbjct: 199 FGANGVILPERRSASVTAAAWKVSAGAAAHLPVARVVNLNKAIQGLRERGWYAIGLDGGG 258

Query: 101 NAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYE 160
           + +       T P  +++G E  G+++      D    IP+   V+SLN SVA+ + LY 
Sbjct: 259 DKLVGETGFETDPLVVVLGSEGKGMSRLTREACDAIAGIPISSAVESLNASVAAGISLYA 318

Query: 161 AQRQRQNAGM 170
               R+ A +
Sbjct: 319 VANARRLAAL 328


>UniRef50_O30272 Uncharacterized tRNA/rRNA methyltransferase AF_2399 n=2
           Tax=Archaeoglobaceae RepID=Y2399_ARCFU
          Length = 224

 Score =  184 bits (469), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 42/169 (24%), Positives = 71/169 (42%), Gaps = 6/169 (3%)

Query: 1   MNPTRYARICEMLARR--QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS--R 56
           ++P +YA    ++ +        + ++ V    N+ A IRTA+  G   V          
Sbjct: 57  VSPIKYADFEFIVKKALTGGSFILFLDNVVDQRNIGACIRTAEFFGAAGVVLPKRRVGSI 116

Query: 57  MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
                 A+AG+   + +        A+  LK  G   LA  L     D   +    P  +
Sbjct: 117 QEGAVKASAGAVFHIPIARVENFASAIKKLKKLGFTTLAADLDGE--DLEAVSLLLPAAV 174

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           ++G E  G+++      D  + IP +G V SLN+SVA+ + LY   RQ+
Sbjct: 175 VIGGEDRGVSRPVKKQCDFVVKIPGVGKVNSLNLSVAAGIFLYTLSRQK 223


>UniRef50_C2KTT3 TrmH family tRNA/rRNA methyltransferase n=2 Tax=Mobiluncus mulieris
           RepID=C2KTT3_9ACTO
          Length = 354

 Score =  184 bits (468), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 42/152 (27%), Positives = 71/152 (46%), Gaps = 4/152 (2%)

Query: 17  QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAGSNSWVQVK 74
            P L V ++QV  PHN+ A++R+A A G   V      +     A    +AG+ + V V 
Sbjct: 204 HPPLLVALDQVTDPHNLGAVLRSAAAFGADGVIIPEHRAASVNAAAWKVSAGAAAIVPVA 263

Query: 75  THRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR-PTCILMGQEKTGITQEALALA 133
               +  A+  LK  G  ++        V   ++  T  P  ++ G E  GI++      
Sbjct: 264 QATNLTRALQDLKRAGAFVIGLD-GGGDVALPDLQLTDVPLVVVTGSEGRGISRLVRDTC 322

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           DQ + IP+   ++SLN +VA+ + LY+   +R
Sbjct: 323 DQIVSIPIAPRMESLNAAVATGIALYQIAVRR 354


>UniRef50_C1E8J5 Predicted protein (Fragment) n=3 Tax=Mamiellales RepID=C1E8J5_9CHLO
          Length = 234

 Score =  184 bits (468), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 56/204 (27%), Positives = 103/204 (50%), Gaps = 6/204 (2%)

Query: 1   MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEV-HAVWPGSRMRT 59
           ++  R AR+  ++ +R  DL   +E V+   NV A+ R+ +A+G+  +      G   + 
Sbjct: 28  VSEERIARLDAVVQQRSFDLMPILEGVYDIGNVLAVCRSTEALGIGSLGVISDAGLAFKQ 87

Query: 60  MASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMG 119
               + G+  W  ++  R+  +A+  +K +G ++L T + +        D+T PT +++G
Sbjct: 88  SGRTSGGAVKWTNLEQWRSTEEAIREVKARGYRVL-TTVFEGGHPLEHYDWTVPTAVILG 146

Query: 120 QEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENSMLP 179
            E+ G++ EA  LAD  + I M G  +SLNVSVAS++I++ A + R      L  +  L 
Sbjct: 147 NERDGVSDEAKRLADGGVYISMNGFTESLNVSVASSMIMHHAVQDRTR---RLGSHGNLS 203

Query: 180 EAEQQRLLFEGGYPVLAKVAKRKG 203
           E E++ L        L    ++ G
Sbjct: 204 EREKETLRAVYL-ARLVPRYQKHG 226


>UniRef50_D2EID2 TrmH family RNA methyltransferase n=1 Tax=Pediococcus acidilactici
           7_4 RepID=D2EID2_PEDAC
          Length = 256

 Score =  184 bits (468), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 35/147 (23%), Positives = 68/147 (46%), Gaps = 3/147 (2%)

Query: 15  RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAGSNSWVQ 72
                  + ++ V  P N+  ++RTADA G   V      +         A  GS   +Q
Sbjct: 107 NDTTGQWLLLDNVQDPGNIGTMVRTADAAGFTGVIFGSGTADFYNPKILRAMQGSQYHLQ 166

Query: 73  VKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALAL 132
           +K    +   +         +  + L ++A  +R+ID  +   ++MG E  G++ E +  
Sbjct: 167 LKRL-NLQKWIEACHQAHQAVYGSILDEHAQSYRDIDAPKDFSLIMGNEGNGMSPELVKA 225

Query: 133 ADQDIIIPMIGMVQSLNVSVASALILY 159
            D ++ IP+ G  +SLNV+VA+ ++++
Sbjct: 226 TDCNLYIPIKGNAESLNVAVAAGVLMF 252


>UniRef50_UPI0001BC4585 23S rRNA methyltransferase n=1 Tax=Fusobacterium sp. D12
           RepID=UPI0001BC4585
          Length = 224

 Score =  184 bits (467), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 36/141 (25%), Positives = 71/141 (50%), Gaps = 3/141 (2%)

Query: 21  TVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAGSNSWVQVKTHRT 78
            + ++ +  P N+  +IR  DA G  ++             +  ++ GS   V++     
Sbjct: 75  LIVLDDIQDPGNLGTMIRLVDAAGFSDIFLTKHSVDCYNEKVVRSSMGSIFHVRLHVMEK 134

Query: 79  IGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDII 138
             + + +L+ +   +L T L  ++V + E+        + G E  G+++E L LA+Q II
Sbjct: 135 -KEILEYLQTENYHVLVTTLQRDSVAYTEMQLKEKNAFVFGNEGHGVSKEFLELAEQKII 193

Query: 139 IPMIGMVQSLNVSVASALILY 159
           IP+ G  +SLNV++A+ +IL+
Sbjct: 194 IPISGQAESLNVAMAAGIILF 214


>UniRef50_B5YIM1 RNA methyltransferase, TrmH family n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YIM1_THEYD
          Length = 261

 Score =  184 bits (467), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 9/172 (5%)

Query: 1   MNPTRYARICEMLARR-----QPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGS 55
           + P     I +   +       P   V  +++  P N+  IIR A+A G   V       
Sbjct: 87  VTPQGVFAIADFKIKNINDLSNPTFIVIADRIQDPGNIGTIIRAAEAFGAEAVLVTHGTC 146

Query: 56  RMRTMA--SAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRP 113
              +     A+AGS  ++ V     + +    +   G+ ++ T L    +    +D+T+P
Sbjct: 147 NPFSNKALRASAGSIFFLPVIKVT-VKEIEEFVSKYGLNLVITDL-KATISSFNMDFTKP 204

Query: 114 TCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
             I+ G E  G++Q+  A+      IP  G  +SLNV++A+  ILYE  RQR
Sbjct: 205 LAIVFGNESKGVSQDLRAIKHTSCKIPHKGKAESLNVAMAATAILYEILRQR 256


>UniRef50_A9WLY5 23S rRNA methyltransferase TrmH, group 3 n=11 Tax=Actinobacteria
           (class) RepID=A9WLY5_RENSM
          Length = 336

 Score =  184 bits (467), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 43/163 (26%), Positives = 69/163 (42%), Gaps = 3/163 (1%)

Query: 16  RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR--MRTMASAAAGSNSWVQV 73
           +   L V ++ +  P N+ AIIR+  A     V      S     +    +AG+   V V
Sbjct: 173 KNSPLIVALDGITDPRNLGAIIRSVSAFAGQAVIVPERRSVGLTASAWKTSAGAAVRVPV 232

Query: 74  KTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALA 133
                +  A+   KG G  +L      +           P CI++G E  G+++      
Sbjct: 233 ARAGNLNRALESFKGMGYFVLGLDGDGDVSLPALAVAKEPVCIVVGSEGKGLSRLVRENC 292

Query: 134 DQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAGMYLRENS 176
           DQ + IP+   ++SLN S+A  + LYE  RQR + G   + N 
Sbjct: 293 DQIVSIPIDSAMESLNASMAVGITLYEIARQR-SGGSAEQGNP 334


>UniRef50_A5US41 tRNA/rRNA methyltransferase (SpoU) n=4 Tax=Chloroflexaceae
           RepID=A5US41_ROSS1
          Length = 262

 Score =  183 bits (466), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 45/169 (26%), Positives = 85/169 (50%), Gaps = 6/169 (3%)

Query: 1   MNPTRYARICE--MLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMR 58
           ++P     +     +A  +P L + ++ V  P N+  ++R+A+AVGV +V        + 
Sbjct: 91  VHPQGVVALASWPHVAPGKPGLLLVIDAVQDPGNLGTLLRSAEAVGVAQVLCSVGTVDLY 150

Query: 59  --TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCI 116
              +  +A G++  + ++   +       L      + A       + +   D+ +P+ +
Sbjct: 151 APKVVRSAMGAHFRLAMEQDLSWDAIGERLASVD-HVYAADPEAR-MPYYAADWRQPSAL 208

Query: 117 LMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
           L+G E  G++  A  LA + I IPM G  +SLNV+VA+++IL+EA RQR
Sbjct: 209 LVGNEAHGLSDAARRLATKQIAIPMRGGTESLNVAVAASVILFEALRQR 257


>UniRef50_A8DJH5 TsnR n=1 Tax=Candidatus Chloracidobacterium thermophilum
           RepID=A8DJH5_9BACT
          Length = 282

 Score =  183 bits (466), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 47/163 (28%), Positives = 79/163 (48%), Gaps = 8/163 (4%)

Query: 13  LARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMA--SAAAGSNSW 70
           L      L V  + +  P N+ A+IRTA+A G   +                AAAGS   
Sbjct: 110 LTHHPAPLFVLADGIQSPGNLGALIRTAEAAGATGILVTVGTVDPFQPKALRAAAGSAFR 169

Query: 71  VQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEA- 129
           + +    ++ D +  L  QG++++   +  +   +   D+ +P  + +G E  G+     
Sbjct: 170 LPIIAGSSVADELQKLYRQGVRLVTADIHGD-TPYEAFDWRQPVLLWLGSEGHGLRSLTD 228

Query: 130 ---LALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
                LA + + IPM G V+SLNV+VA A++LYEA+RQR+ + 
Sbjct: 229 DFKHRLAARLV-IPMEGQVESLNVAVAGAILLYEARRQRRQSS 270


>UniRef50_Q7MW92 RNA methyltransferase, TrmH family n=2 Tax=Porphyromonas gingivalis
           RepID=Q7MW92_PORGI
          Length = 254

 Score =  183 bits (466), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 45/176 (25%), Positives = 83/176 (47%), Gaps = 15/176 (8%)

Query: 2   NPTRYARICEMLARRQP---DLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM- 57
            P     + ++ A  +P    LT+ ++ V  P NV  I+RTAD  G+  V      + + 
Sbjct: 80  TPQPLMAVFDLPAEPEPVVEGLTLLLDGVQDPGNVGTILRTADWFGIRHVWLGTGSADVF 139

Query: 58  -RTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREI---DYTRP 113
              +  A+ G+ + VQ    +   D +A+ + QG+ +    L   +    E    ++T P
Sbjct: 140 SPKVVQASMGALARVQPTPLKNTVDTLAYFRRQGIPVYGAFLDGQS--LYEAPLPNFTEP 197

Query: 114 TCILMGQEKTGITQEALALADQDIIIP-----MIGMVQSLNVSVASALILYEAQRQ 164
             +++G E  GI+ E  A     + IP     + G  +SLNV++A+A++  E +R+
Sbjct: 198 AILVLGSEGRGISPEVAAEITDRLTIPASGLSVKGHTESLNVAIATAILCSEWRRR 253


>UniRef50_B6YR56 23S rRNA (Guanosine-2'-O-)-methyltransferase n=1 Tax=Candidatus
           Azobacteroides pseudotrichonymphae genomovar. CFP2
           RepID=B6YR56_AZOPC
          Length = 274

 Score =  183 bits (465), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 49/161 (30%), Positives = 81/161 (50%), Gaps = 4/161 (2%)

Query: 9   ICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRT--MASAAAG 66
           +   L      L + +E + KP N+ AI+RTA+A  +       P + +    +  ++ G
Sbjct: 114 LLADLNLSNNPLIIVLESIEKPGNLGAILRTAEAAKIDATIICNPSTDIYNPNVVRSSIG 173

Query: 67  SNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGIT 126
                 +       + +A+LK + +QI A  L+     +   D+T  + I++G E  G+T
Sbjct: 174 CLFSNPIAVASN-EETLAYLKSKSVQIFAAELTAFKQ-YYNTDFTSASAIVIGAEVNGLT 231

Query: 127 QEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
              L  A Q I IPM G++ SLNVSV+ A+I +EA RQR +
Sbjct: 232 NFWLDNAHQRIKIPMQGIIDSLNVSVSVAIITFEAIRQRNS 272


>UniRef50_UPI00016C0619 tRNA/rRNA methyltransferase (SpoU) n=1 Tax=Epulopiscium sp. 'N.t.
           morphotype B' RepID=UPI00016C0619
          Length = 262

 Score =  183 bits (465), Expect = 5e-45,   Method: Composition-based stats.
 Identities = 40/175 (22%), Positives = 77/175 (44%), Gaps = 10/175 (5%)

Query: 2   NPTRYARICEMLAR-------RQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPG 54
            P     I +   +       +Q    + +E +  P N+  I+RTA  + V  +      
Sbjct: 86  TPQGLMAIVKQRNKSLNDFTIKQNGTYLILEGIKDPGNLGTIVRTAYGLFVDAIFLTKDC 145

Query: 55  SRMR--TMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTR 112
             +    +  A  G+ S + +  +  +   V   +   ++I AT L   + +     +  
Sbjct: 146 VELYSPKVVRATMGAISKIDIIRNYEMTSYVDFFRENKVKIYATDLY-QSNNLYTTKFDG 204

Query: 113 PTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQN 167
            + I++G E TGI++   A AD  I IP    ++SLN ++A++++LYE  RQ+  
Sbjct: 205 SSAIVIGNEATGISEYTRAQADSTIKIPTRDNLESLNAAIATSIVLYEVARQKNF 259


>UniRef50_B2KBE6 RNA methyltransferase, TrmH family, group 3 n=1 Tax=Elusimicrobium
           minutum Pei191 RepID=B2KBE6_ELUMP
          Length = 249

 Score =  182 bits (464), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 39/168 (23%), Positives = 81/168 (48%), Gaps = 8/168 (4%)

Query: 1   MNPTRYARICEMLA---RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSR- 56
           + P +  R+ + +      + DL + ++++  P N+ +IIR+A  +G   +      +  
Sbjct: 78  VEPVKIMRLIDAIDVSRGNKKDLWIAVDEMTDPQNLGSIIRSAACLGFSTIILPSRRTVG 137

Query: 57  -MRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTC 115
              ++   A+G+   V V     +  A+  LK +G  I    +   ++   + DY+ P  
Sbjct: 138 LTPSVYKVASGATEKVTVVEVANLATALLDLKDEGFWIYGADMGGQSIV--KTDYSFPAV 195

Query: 116 ILMGQEKTGITQEALALADQDIIIPM-IGMVQSLNVSVASALILYEAQ 162
           +++G E TGI ++     DQ + IP   G V SLN + A+++I+++  
Sbjct: 196 LVVGSEGTGIREKTAEHCDQVVSIPQAPGSVDSLNAANAASIIMFDMF 243


>UniRef50_C5SHP3 RNA methyltransferase, TrmH family, group 3 n=3
           Tax=Caulobacteraceae RepID=C5SHP3_9CAUL
          Length = 322

 Score =  182 bits (464), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 44/158 (27%), Positives = 67/158 (42%), Gaps = 10/158 (6%)

Query: 15  RRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRM--RTMASAAAGSNSWVQ 72
           R++  + V ++QV  P N+ AI+RT  A G   +      S +    +A  AAG+   V 
Sbjct: 161 RQERPVLVMLDQVTDPQNIGAILRTCAAFGAAGLIMQDRHSPVMQGVLAKTAAGAMDRVP 220

Query: 73  VKTHRTIGDAVAHLKGQGMQILATHLSDN--------AVDFREIDYTRPTCILMGQEKTG 124
                 +  A+  L   G   L                  +R+    R   I+MG E  G
Sbjct: 221 FARVTNLSRALESLTENGFVSLGMAGEAEHSLQAVLEQQGWRQAGSPRALVIVMGSEGEG 280

Query: 125 ITQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQ 162
           + +      D  + IPM G  +SLNVS A+++ LYEA 
Sbjct: 281 LRRLVAEHCDHLVKIPMPGGFESLNVSHATSIALYEAL 318


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.312    0.188    0.592 

Lambda     K      H
   0.267   0.0577    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,803,354,737
Number of Sequences: 3077464
Number of extensions: 102377802
Number of successful extensions: 242297
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 2604
Number of HSP's successfully gapped in prelim test: 605
Number of HSP's that attempted gapping in prelim test: 234829
Number of HSP's gapped (non-prelim): 3449
length of query: 229
length of database: 1,040,396,356
effective HSP length: 124
effective length of query: 105
effective length of database: 658,790,820
effective search space: 69173036100
effective search space used: 69173036100
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (20.9 bits)
S2: 92 (39.6 bits)
