Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	T	V	V	F	A	Y	H	D	M	G	C	L	G	I	E	A	L	L	A	A	G	Y	E	I	S	A	I	F	T	H	T	D	N	P	G	E	K	A	F	Y	G	S	V	A	R	L	A	A	E	R	G	I	P	V	Y	A	P	D
Secondary structure
SS confidence
Disorder		?																																				?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		N	V	N	H	P	L	W	V	E	R	I	A	Q	L	S	P	D	V	I	F	S	F	Y	Y	R	H	L	I	Y	D	E	I	L	Q	L	A	P	A	G	A	F	N	L	H	G	S	L	L	P	K	Y	R	G	R	A	P	L	N	W	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	V	N	G	E	T	E	T	G	V	T	L	H	R	M	V	K	R	A	D	A	G	A	I	V	A	Q	L	R	I	A	I	A	P	D	D	I	A	I	T	L	H	H	K	L	C	H	A	A	R	Q	L	L	E	Q	T	L	P	A	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		K	H	G	N	I	L	E	I	A	Q	R	E	N	E	A	T	C	F	G	R	R	T	P	D	D	S	F	L	E	W	H	K	P	A	S	V	L	H	N	M	V	R	A	V	A	D	P	W	P	G	A	F	S	Y	V	G	N	Q	K	F
Secondary structure
SS confidence
Disorder				?					?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		T	V	W	S	S	R	V	H	P	H	A	S	K	A	Q	P	G	S	V	I	S	V	A	P	L	L	I	A	C	G	D	G	A	L	E	I	V	T	G	Q	A	G	D	G	I	T	M	Q	G	S	Q	L	A	Q	T	L	G	L	V	Q
Secondary structure
SS confidence
Disorder										?	?	?	?	?			?																												?														?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	S	R	L	N	S	Q	P	A	C	T	A	R	R	R	T	R	V	L	I	L	G	V	N	G	F	I	G	N	H	L	T	E	R	L	L	R	E	D	H	Y	E	V	Y	G	L	D	I	G	S	D	A	I	S	R	F	L	N	H	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		H	F	H	F	V	E	G	D	I	S	I	H	S	E	W	I	E	Y	H	V	K	K	C	D	V	V	L	P	L	V	A	I	A	T	P	I	E	Y	T	R	N	P	L	R	V	F	E	L	D	F	E	E	N	L	R	I	I	R	Y	C
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		V	K	Y	R	K	R	I	I	F	P	S	T	S	E	V	Y	G	M	C	S	D	K	Y	F	D	E	D	H	S	N	L	I	V	G	P	V	N	K	P	R	W	I	Y	S	V	S	K	Q	L	L	D	R	V	I	W	A	Y	G	E	K
Secondary structure
SS confidence
Disorder																																	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		E	G	L	Q	F	T	L	F	R	P	F	N	W	M	G	P	R	L	D	N	L	N	A	A	R	I	G	S	S	R	A	I	T	Q	L	I	L	N	L	V	E	G	S	P	I	K	L	I	D	G	G	K	Q	K	R	C	F	T	D	I
Secondary structure
SS confidence
Disorder																						?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		R	D	G	I	E	A	L	Y	R	I	I	E	N	A	G	N	R	C	D	G	E	I	I	N	I	G	N	P	E	N	E	A	S	I	E	E	L	G	E	M	L	L	A	S	F	E	K	H	P	L	R	H	H	F	P	P	F	A	G	F
Secondary structure
SS confidence
Disorder																																																		?	?	?	?					?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence		R	V	V	E	S	S	S	Y	Y	G	K	G	Y	Q	D	V	E	H	R	K	P	S	I	R	N	A	H	R	C	L	D	W	E	P	K	I	D	M	Q	E	T	I	D	E	T	L	D	F	F	L	R	T	V	D	L	T	D	K	P	S
Secondary structure
SS confidence
Disorder		?	?	?				?	?	?	?	?	?																																										?	?	?	?	?	?	?
Disorder confidence
Sequence
Secondary structure
SS confidence
Disorder
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1z7e chain C Region: 1 - 656 Aligned: 639 Modelled: 656 Confidence: 100.0% Identity: 100% PDB header:hydrolase Chain: C: PDB Molecule:protein arna; PDBTitle: crystal structure of full length arna Phyre2 PDB 1yrw chain A Region: 1 - 300 Aligned: 291 Modelled: 300 Confidence: 100.0% Identity: 100% PDB header:transferase Chain: A: PDB Molecule:protein arna; PDBTitle: crystal structure of e.coli arna transformylase domain Phyre2 PDB 1fmt chain A Region: 1 - 304 Aligned: 300 Modelled: 304 Confidence: 100.0% Identity: 29% PDB header:formyltransferase Chain: A: PDB Molecule:methionyl-trna fmet formyltransferase; PDBTitle: methionyl-trnafmet formyltransferase from escherichia coli Phyre2 PDB 3rfo chain A Region: 1 - 305 Aligned: 304 Modelled: 305 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:methionyl-trna formyltransferase; PDBTitle: crystal structure of methyionyl-trna formyltransferase from bacillus2 anthracis Phyre2 PDB 3tqq chain A Region: 1 - 304 Aligned: 296 Modelled: 304 Confidence: 100.0% Identity: 25% PDB header:transferase Chain: A: PDB Molecule:methionyl-trna formyltransferase; PDBTitle: structure of the methionyl-trna formyltransferase (fmt) from coxiella2 burnetii Phyre2 PDB 3q0i chain A Region: 1 - 304 Aligned: 297 Modelled: 298 Confidence: 100.0% Identity: 26% PDB header:transferase Chain: A: PDB Molecule:methionyl-trna formyltransferase; PDBTitle: methionyl-trna formyltransferase from vibrio cholerae Phyre2 PDB 1s3i chain A Region: 1 - 294 Aligned: 290 Modelled: 294 Confidence: 100.0% Identity: 28% PDB header:hydrolase, oxidoreductase Chain: A: PDB Molecule:10-formyltetrahydrofolate dehydrogenase; PDBTitle: crystal structure of the n terminal hydrolase domain of 10-2 formyltetrahydrofolate dehydrogenase Phyre2 PDB 1z45 chain A Region: 315 - 652 Aligned: 309 Modelled: 314 Confidence: 100.0% Identity: 18% PDB header:isomerase Chain: A: PDB Molecule:gal10 bifunctional protein; PDBTitle: crystal structure of the gal10 fusion protein galactose2 mutarotase/udp-galactose 4-epimerase from saccharomyces3 cerevisiae complexed with nad, udp-glucose, and galactose Phyre2 PDB 1i24 chain A Region: 315 - 658 Aligned: 330 Modelled: 343 Confidence: 100.0% Identity: 17% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Tyrosine-dependent oxidoreductases Phyre2 PDB 2bln chain A domain 2 Region: 1 - 203 Aligned: 197 Modelled: 203 Confidence: 100.0% Identity: 99% Fold: Formyltransferase Superfamily: Formyltransferase Family: Formyltransferase Phyre2 PDB 2bw0 chain A domain 2 Region: 1 - 199 Aligned: 196 Modelled: 199 Confidence: 100.0% Identity: 27% Fold: Formyltransferase Superfamily: Formyltransferase Family: Formyltransferase Phyre2 PDB 1fmt chain A domain 2 Region: 1 - 200 Aligned: 197 Modelled: 200 Confidence: 100.0% Identity: 30% Fold: Formyltransferase Superfamily: Formyltransferase Family: Formyltransferase Phyre2 PDB 1s3i chain A domain 2 Region: 1 - 199 Aligned: 196 Modelled: 196 Confidence: 100.0% Identity: 26% Fold: Formyltransferase Superfamily: Formyltransferase Family: Formyltransferase Phyre2 PDB 2bll chain A domain 1 Region: 316 - 657 Aligned: 330 Modelled: 342 Confidence: 100.0% Identity: 100% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Tyrosine-dependent oxidoreductases Phyre2 PDB 1zgh chain A Region: 2 - 261 Aligned: 223 Modelled: 231 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:methionyl-trna formyltransferase; PDBTitle: methionyl-trna formyltransferase from clostridium thermocellum Phyre2 PDB 2b69 chain A domain 1 Region: 315 - 653 Aligned: 308 Modelled: 323 Confidence: 100.0% Identity: 26% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Tyrosine-dependent oxidoreductases Phyre2 PDB 2b69 chain A Region: 315 - 653 Aligned: 308 Modelled: 318 Confidence: 100.0% Identity: 26% PDB header:lyase Chain: A: PDB Molecule:udp-glucuronate decarboxylase 1; PDBTitle: crystal structure of human udp-glucoronic acid decarboxylase Phyre2 PDB 3slg chain B Region: 314 - 653 Aligned: 326 Modelled: 340 Confidence: 100.0% Identity: 51% PDB header:transferase Chain: B: PDB Molecule:pbgp3 protein; PDBTitle: crystal structure of pbgp3 protein from burkholderia pseudomallei Phyre2 PDB 3kcq chain A Region: 1 - 213 Aligned: 198 Modelled: 213 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase; PDBTitle: crystal structure of phosphoribosylglycinamide formyltransferase from2 anaplasma phagocytophilum Phyre2 PDB 1e6u chain A Region: 315 - 652 Aligned: 303 Modelled: 308 Confidence: 100.0% Identity: 16% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Tyrosine-dependent oxidoreductases Phyre2 1 c1z7eC_ 2 c1yrwA_ 3 c1fmtA_ 4 c3rfoA_ 5 c3tqqA_ 6 c3q0iA_ 7 c1s3iA_ 8 c1z45A_ 9 d1i24a_ 10 d2blna2 11 d2bw0a2 12 d1fmta2 13 d1s3ia2 14 d2blla1 15 c1zghA_ 16 d2b69a1 17 c2b69A_ 18 c3slgB_ 19 c3kcqA_ 20 d1e6ua_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499