Phyre 2 Results for P18392

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Email | l.a.kelley@imperial.ac.uk
Description | P18392
Date | Thu Jan 5 11:36:55 GMT 2012
Unique Job ID | 02085f6bdf69d422

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c3d2rB_
Top template information
PDB header:transferase Chain: B: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 4; PDBTitle: crystal structure of pyruvate dehydrogenase kinase isoform 4 in2 complex with adp
Confidence and coverage
Confidence: | 100.0% | Coverage: | 63%
274 residues ( 63% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | K | K | L | F | I | Q | F | Y | L | L | L | F | V | C | F | L | V | M | S | L | L | V | G | L | V | Y | K | F | T | A | E | R | A | G | K | Q | S | L | D | D | L | M | N | S | S | L | Y | L | M | R | S | E | L | R | E | I | P | P | H
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | D | W | G | K | T | L | K | E | M | D | L | N | L | S | F | D | L | R | V | E | P | L | S | K | Y | H | L | D | D | I | S | M | H | R | L | R | G | G | E | I | V | A | L | D | D | Q | Y | T | F | L | Q | R | I | P | R | S | H | Y | V | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | A | V | G | P | V | P | Y | L | Y | Y | L | H | Q | M | R | L | L | D | I | A | L | I | A | F | I | A | I | S | L | A | F | P | V | F | I | W | M | R | P | H | W | Q | D | M | L | K | L | E | A | A | A | Q | R | F | G | D | G | H | L | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | E | R | I | H | F | D | E | G | S | S | F | E | R | L | G | V | A | F | N | Q | M | A | D | N | I | N | A | L | I | A | S | K | K | Q | L | I | D | G | I | A | H | E | L | R | T | P | L | V | R | L | R | Y | R | L | E | M | S | D | N | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | S | A | A | E | S | Q | A | L | N | R | D | I | S | Q | L | E | A | L | I | E | E | L | L | T | Y | A | R | L | D | R | P | Q | N | E | L | H | L | S | E | P | D | L | P | L | W | L | S | T | H | L | A | D | I | Q | A | V | T | P | D | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | T | V | R | I | K | T | L | V | Q | G | H | Y | A | A | L | D | M | R | L | M | E | R | V | L | D | N | L | L | N | N | A | L | R | Y | C | H | S | T | V | E | T | S | L | L | L | S | G | N | R | A | T | L | I | V | E | D | D | G | P | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | I | A | P | E | N | R | E | H | I | F | E | P | F | V | R | L | D | P | S | R | D | R | S | T | G | G | C | G | L | G | L | A | I | V | H | S | I | A | L | A | M | G | G | T | V | N | C | D | T | S | E | L | G | G | A | R | F | S | F | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | .
Sequence |  | W | P | L | W | H | N | I | P | Q | F | T | S | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c3d2rB_ |

### PDB 3d2r chain B

Region: 151 - 426
Aligned: 274
Modelled: 276
Confidence: 100.0%
Identity: 12%
PDB header:transferase
Chain: B: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 4;
PDBTitle: crystal structure of pyruvate dehydrogenase kinase isoform 4 in2 complex with adp

Phyre2
2 |
| c2q8fA_ |

### PDB 2q8f chain A

Region: 152 - 423
Aligned: 268
Modelled: 268
Confidence: 100.0%
Identity: 12%
PDB header:transferase
Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 1;
PDBTitle: structure of pyruvate dehydrogenase kinase isoform 1

Phyre2
3 |
| c2bu8A_ |

### PDB 2bu8 chain A

Region: 149 - 426
Aligned: 272
Modelled: 278
Confidence: 100.0%
Identity: 11%
PDB header:transferase
Chain: A: PDB Molecule:pyruvate dehydrogenase kinase isoenzyme 2;
PDBTitle: crystal structures of human pyruvate dehydrogenase kinase 22 containing physiological and synthetic ligands

Phyre2
4 |
| c3d36B_ |

### PDB 3d36 chain B

Region: 205 - 424
Aligned: 211
Modelled: 220
Confidence: 100.0%
Identity: 23%
PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:sporulation kinase b;
PDBTitle: how to switch off a histidine kinase: crystal structure of2 geobacillus stearothermophilus kinb with the inhibitor sda

Phyre2
5 |
| c2c2aA_ |

### PDB 2c2a chain A

Region: 199 - 425
Aligned: 218
Modelled: 227
Confidence: 100.0%
Identity: 28%
PDB header:transferase
Chain: A: PDB Molecule:sensor histidine kinase;
PDBTitle: structure of the entire cytoplasmic portion of a sensor2 histidine kinase protein

Phyre2
6 |
| c1y8oA_ |

### PDB 1y8o chain A

Region: 155 - 423
Aligned: 260
Modelled: 269
Confidence: 100.0%
Identity: 11%
PDB header:transferase
Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 3;
PDBTitle: crystal structure of the pdk3-l2 complex

Phyre2
7 |
| c1gjvA_ |

### PDB 1gjv chain A

Region: 165 - 423
Aligned: 251
Modelled: 259
Confidence: 100.0%
Identity: 14%
PDB header:transferase
Chain: A: PDB Molecule:[3-methyl-2-oxobutanoate dehydrogenase
PDBTitle: branched-chain alpha-ketoacid dehydrogenase kinase (bck)2 complxed with atp-gamma-s

Phyre2
8 |
| d1id0a_ |

### PDB 1id0 chain A

Region: 277 - 425
Aligned: 145
Modelled: 149
Confidence: 100.0%
Identity: 29%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2
9 |
| d1bxda_ |

### PDB 1bxd chain A

Region: 270 - 432
Aligned: 158
Modelled: 163
Confidence: 100.0%
Identity: 35%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2
10 |
| c3a0rA_ |

### PDB 3a0r chain A

Region: 199 - 426
Aligned: 215
Modelled: 228
Confidence: 100.0%
Identity: 18%
PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360)

Phyre2
11 |
| d2c2aa2 |

### PDB 2c2a chain A domain 2

Region: 274 - 425
Aligned: 143
Modelled: 152
Confidence: 100.0%
Identity: 28%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2
12 |
| d1jm6a2 |

### PDB 1jm6 chain A domain 2

Region: 278 - 426
Aligned: 145
Modelled: 149
Confidence: 100.0%
Identity: 16%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: alpha-ketoacid dehydrogenase kinase, C-terminal domain

Phyre2
13 |
| c3a0tA_ |

### PDB 3a0t chain A

Region: 275 - 426
Aligned: 146
Modelled: 152
Confidence: 100.0%
Identity: 22%
PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: catalytic domain of histidine kinase thka (tm1359) in2 complex with adp and mg ion (trigonal)

Phyre2
14 |
| d1gkza2 |

### PDB 1gkz chain A domain 2

Region: 278 - 429
Aligned: 147
Modelled: 152
Confidence: 100.0%
Identity: 15%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: alpha-ketoacid dehydrogenase kinase, C-terminal domain

Phyre2
15 |
| c1b3qA_ |

### PDB 1b3q chain A

Region: 220 - 429
Aligned: 202
Modelled: 210
Confidence: 100.0%
Identity: 19%
PDB header:transferase
Chain: A: PDB Molecule:protein (chemotaxis protein chea);
PDBTitle: crystal structure of chea-289, a signal transducing histidine kinase

Phyre2
16 |
| d1ysra1 |

### PDB 1ysr chain A domain 1

Region: 276 - 424
Aligned: 134
Modelled: 135
Confidence: 99.9%
Identity: 27%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2
17 |
| c2ch4A_ |

### PDB 2ch4 chain A

Region: 280 - 429
Aligned: 149
Modelled: 150
Confidence: 99.9%
Identity: 23%
PDB header:transferase/chemotaxis
Chain: A: PDB Molecule:chemotaxis protein chea;
PDBTitle: complex between bacterial chemotaxis histidine kinase chea2 domains p4 and p5 and receptor-adaptor protein chew

Phyre2
18 |
| c3jz3B_ |

### PDB 3jz3 chain B

Region: 239 - 423
Aligned: 154
Modelled: 156
Confidence: 99.9%
Identity: 31%
PDB header:transferase
Chain: B: PDB Molecule:sensor protein qsec;
PDBTitle: structure of the cytoplasmic segment of histidine kinase qsec

Phyre2
19 |
| d1i58a_ |

### PDB 1i58 chain A

Region: 277 - 423
Aligned: 146
Modelled: 147
Confidence: 99.9%
Identity: 23%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2
20 |
| d1r62a_ |

### PDB 1r62 chain A

Region: 277 - 425
Aligned: 135
Modelled: 144
Confidence: 99.9%
Identity: 21%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c3d2rB_ |
|  | 100.0 | 12 | PDB header:transferase Chain: B: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 4; PDBTitle: crystal structure of pyruvate dehydrogenase kinase isoform 4 in2 complex with adp
2 | c2q8fA_ |
|  | 100.0 | 12 | PDB header:transferase Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 1; PDBTitle: structure of pyruvate dehydrogenase kinase isoform 1
3 | c2bu8A_ |
|  | 100.0 | 11 | PDB header:transferase Chain: A: PDB Molecule:pyruvate dehydrogenase kinase isoenzyme 2; PDBTitle: crystal structures of human pyruvate dehydrogenase kinase 22 containing physiological and synthetic ligands
4 | c3d36B_ |
|  | 100.0 | 23 | PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:sporulation kinase b; PDBTitle: how to switch off a histidine kinase: crystal structure of2 geobacillus stearothermophilus kinb with the inhibitor sda
5 | c2c2aA_ |
|  | 100.0 | 28 | PDB header:transferase Chain: A: PDB Molecule:sensor histidine kinase; PDBTitle: structure of the entire cytoplasmic portion of a sensor2 histidine kinase protein
6 | c1y8oA_ |
|  | 100.0 | 11 | PDB header:transferase Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 3; PDBTitle: crystal structure of the pdk3-l2 complex
7 | c1gjvA_ |
|  | 100.0 | 14 | PDB header:transferase Chain: A: PDB Molecule:[3-methyl-2-oxobutanoate dehydrogenase PDBTitle: branched-chain alpha-ketoacid dehydrogenase kinase (bck)2 complxed with atp-gamma-s
8 | d1id0a_ |
|  | 100.0 | 29 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase
9 | d1bxda_ |
|  | 100.0 | 35 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase
10 | c3a0rA_ |
|  | 100.0 | 18 | PDB header:transferase Chain: A: PDB Molecule:sensor protein; PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360)
11 | d2c2aa2 |
|  | 100.0 | 28 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase
12 | d1jm6a2 |
|  | 100.0 | 16 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:alpha-ketoacid dehydrogenase kinase, C-terminal domain
13 | c3a0tA_ |
|  | 100.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:sensor protein; PDBTitle: catalytic domain of histidine kinase thka (tm1359) in2 complex with adp and mg ion (trigonal)
14 | d1gkza2 |
|  | 100.0 | 15 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:alpha-ketoacid dehydrogenase kinase, C-terminal domain
15 | c1b3qA_ |
|  | 100.0 | 19 | PDB header:transferase Chain: A: PDB Molecule:protein (chemotaxis protein chea); PDBTitle: crystal structure of chea-289, a signal transducing histidine kinase
16 | d1ysra1 |
|  | 99.9 | 27 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase
17 | c2ch4A_ |
|  | 99.9 | 23 | PDB header:transferase/chemotaxis Chain: A: PDB Molecule:chemotaxis protein chea; PDBTitle: complex between bacterial chemotaxis histidine kinase chea2 domains p4 and p5 and receptor-adaptor protein chew
18 | c3jz3B_ |
|  | 99.9 | 31 | PDB header:transferase Chain: B: PDB Molecule:sensor protein qsec; PDBTitle: structure of the cytoplasmic segment of histidine kinase qsec
19 | d1i58a_ |
|  | 99.9 | 23 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase
20 | d1r62a_ |
|  | 99.9 | 21 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase
21 | c3gieA_ |
| not modelled | 99.8 | 16 | PDB header:transferase Chain: A: PDB Molecule:sensor histidine kinase desk; PDBTitle: crystal structure of deskc_h188e in complex with amp-pcp
22 | d2hkja3 |
| not modelled | 99.8 | 19 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
23 | c2zbkB_ |
| not modelled | 99.7 | 20 | PDB header:isomerase Chain: B: PDB Molecule:type 2 dna topoisomerase 6 subunit b; PDBTitle: crystal structure of an intact type ii dna topoisomerase:2 insights into dna transfer mechanisms
24 | c1mx0D_ |
| not modelled | 99.7 | 19 | PDB header:isomerase Chain: D: PDB Molecule:type ii dna topoisomerase vi subunit b; PDBTitle: structure of topoisomerase subunit
25 | c3ehgA_ |
| not modelled | 99.7 | 16 | PDB header:transferase Chain: A: PDB Molecule:sensor kinase (yocf protein); PDBTitle: crystal structure of the atp-binding domain of desk in complex with2 atp
26 | c3zxqA_ |
| not modelled | 99.7 | 24 | PDB header:transferase Chain: A: PDB Molecule:hypoxia sensor histidine kinase response regulator dost; PDBTitle: crystal structure of the atp-binding domain of mycobacterium2 tuberculosis dost
27 | c2q2eB_ |
| not modelled | 99.6 | 20 | PDB header:isomerase Chain: B: PDB Molecule:type 2 dna topoisomerase 6 subunit b; PDBTitle: crystal structure of the topoisomerase vi holoenzyme from2 methanosarcina mazei
28 | c3zxoB_ |
| not modelled | 99.6 | 20 | PDB header:transferase Chain: B: PDB Molecule:redox sensor histidine kinase response regulator devs; PDBTitle: crystal structure of the mutant atp-binding domain of2 mycobacterium tuberculosis doss
29 | d1h7sa2 |
| not modelled | 99.6 | 17 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
30 | d1bkna2 |
| not modelled | 99.5 | 16 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
31 | d1th8a_ |
| not modelled | 99.5 | 19 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase
32 | d1b63a2 |
| not modelled | 99.4 | 20 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
33 | d1ixma_ |
| not modelled | 99.4 | 13 | Fold:Sporulation response regulatory protein Spo0B Superfamily:Sporulation response regulatory protein Spo0B Family:Sporulation response regulatory protein Spo0B
34 | d1y8oa2 |
| not modelled | 99.3 | 14 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:alpha-ketoacid dehydrogenase kinase, C-terminal domain
35 | c3zrwB_ |
| not modelled | 99.2 | 21 | PDB header:signaling protein Chain: B: PDB Molecule:af1503 protein, osmolarity sensor protein envz; PDBTitle: the structure of the dimeric hamp-dhp fusion a291v mutant
36 | c3na3A_ |
| not modelled | 98.9 | 21 | PDB header:protein binding Chain: A: PDB Molecule:dna mismatch repair protein mlh1; PDBTitle: mutl protein homolog 1 isoform 1 from homo sapiens
37 | c3lnrA_ |
| not modelled | 98.6 | 11 | PDB header:signaling protein Chain: A: PDB Molecule:aerotaxis transducer aer2; PDBTitle: crystal structure of poly-hamp domains from the p. aeruginosa soluble2 receptor aer2
38 | c3h4lB_ |
| not modelled | 98.6 | 17 | PDB header:dna binding protein, protein binding Chain: B: PDB Molecule:dna mismatch repair protein pms1; PDBTitle: crystal structure of n terminal domain of a dna repair protein
39 | c1bknA_ |
| not modelled | 98.4 | 19 | PDB header:dna repair Chain: A: PDB Molecule:mutl; PDBTitle: crystal structure of an n-terminal 40kd fragment of e. coli2 dna mismatch repair protein mutl
40 | d1kija2 |
| not modelled | 98.4 | 17 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
41 | c1ei1B_ |
| not modelled | 98.3 | 21 | PDB header:isomerase Chain: B: PDB Molecule:dna gyrase b; PDBTitle: dimerization of e. coli dna gyrase b provides a structural mechanism2 for activating the atpase catalytic center
42 | c1y4sA_ |
| not modelled | 98.2 | 20 | PDB header:chaperone Chain: A: PDB Molecule:chaperone protein htpg; PDBTitle: conformation rearrangement of heat shock protein 90 upon2 adp binding
43 | d1ei1a2 |
| not modelled | 98.2 | 21 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
44 | c3iedA_ |
| not modelled | 98.2 | 18 | PDB header:chaperone Chain: A: PDB Molecule:heat shock protein; PDBTitle: crystal structure of n-terminal domain of plasmodium falciparum hsp902 (pf14_0417) in complex with amppn
45 | d1pvga2 |
| not modelled | 98.2 | 21 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
46 | d1s16a2 |
| not modelled | 98.1 | 16 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
47 | d1uyla_ |
| not modelled | 98.1 | 18 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Heat shock protein 90, HSP90, N-terminal domain
48 | c1kijB_ |
| not modelled | 98.1 | 21 | PDB header:isomerase Chain: B: PDB Molecule:dna gyrase subunit b; PDBTitle: crystal structure of the 43k atpase domain of thermus thermophilus2 gyrase b in complex with novobiocin
49 | c2fwyA_ |
| not modelled | 98.0 | 18 | PDB header:chaperone Chain: A: PDB Molecule:heat shock protein hsp 90-alpha; PDBTitle: structure of human hsp90-alpha bound to the potent water2 soluble inhibitor pu-h64
50 | c2cg9A_ |
| not modelled | 98.0 | 19 | PDB header:chaperone Chain: A: PDB Molecule:atp-dependent molecular chaperone hsp82; PDBTitle: crystal structure of an hsp90-sba1 closed chaperone complex
51 | c1ea6A_ |
| not modelled | 98.0 | 23 | PDB header:dna repair Chain: A: PDB Molecule:pms1 protein homolog 2; PDBTitle: n-terminal 40kda fragment of nhpms2 complexed with adp
52 | c2akpA_ |
| not modelled | 97.9 | 15 | PDB header:chaperone Chain: A: PDB Molecule:atp-dependent molecular chaperone hsp82; PDBTitle: hsp90 delta24-n210 mutant
53 | c3pehB_ |
| not modelled | 97.9 | 18 | PDB header:chaperone Chain: B: PDB Molecule:endoplasmin homolog; PDBTitle: crystal structure of the n-terminal domain of an hsp90 from plasmodium2 falciparum, pfl1070c in the presence of a thienopyrimidine derivative
54 | c1s16B_ |
| not modelled | 97.9 | 18 | PDB header:isomerase Chain: B: PDB Molecule:topoisomerase iv subunit b; PDBTitle: crystal structure of e. coli topoisomerase iv pare 43kda subunit2 complexed with adpnp
55 | d2asxa1 |
| not modelled | 97.9 | 12 | Fold:HAMP domain-like Superfamily:HAMP domain-like Family:HAMP domain
56 | d2iwxa1 |
| not modelled | 97.9 | 14 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Heat shock protein 90, HSP90, N-terminal domain
57 | c1zwhA_ |
| not modelled | 97.8 | 14 | PDB header:chaperone Chain: A: PDB Molecule:atp-dependent molecular chaperone hsp82; PDBTitle: yeast hsp82 in complex with the novel hsp90 inhibitor radester amine
58 | c3ke6A_ |
| not modelled | 97.8 | 22 | PDB header:unknown function Chain: A: PDB Molecule:protein rv1364c/mt1410; PDBTitle: the crystal structure of the rsbu and rsbw domains of rv1364c from2 mycobacterium tuberculosis
59 | d1joya_ |
| not modelled | 97.7 | 34 | Fold:ROP-like Superfamily:Homodimeric domain of signal transducing histidine kinase Family:Homodimeric domain of signal transducing histidine kinase
60 | d1uyma_ |
| not modelled | 97.7 | 17 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Heat shock protein 90, HSP90, N-terminal domain
61 | c2iorA_ |
| not modelled | 97.7 | 27 | PDB header:chaperone Chain: A: PDB Molecule:chaperone protein htpg; PDBTitle: crystal structure of the n-terminal domain of htpg, the2 escherichia coli hsp90, bound to adp
62 | c1zxnB_ |
| not modelled | 97.7 | 18 | PDB header:isomerase Chain: B: PDB Molecule:dna topoisomerase ii, alpha isozyme; PDBTitle: human dna topoisomerase iia atpase/adp
63 | d2gqpa1 |
| not modelled | 97.7 | 17 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Heat shock protein 90, HSP90, N-terminal domain
64 | c2iopD_ |
| not modelled | 97.7 | 21 | PDB header:chaperone Chain: D: PDB Molecule:chaperone protein htpg; PDBTitle: crystal structure of full-length htpg, the escherichia coli2 hsp90, bound to adp
65 | c2o1wB_ |
| not modelled | 97.6 | 19 | PDB header:chaperone Chain: B: PDB Molecule:endoplasmin; PDBTitle: structure of n-terminal plus middle domains (n+m) of grp94
66 | c3g7bB_ |
| not modelled | 97.6 | 12 | PDB header:isomerase Chain: B: PDB Molecule:dna gyrase subunit b; PDBTitle: staphylococcus aureus gyrase b co-complex with inhibitor
67 | c1qzrA_ |
| not modelled | 97.5 | 26 | PDB header:isomerase Chain: A: PDB Molecule:dna topoisomerase ii; PDBTitle: crystal structure of the atpase region of saccharomyces cerevisiae2 topoisomerase ii bound to icrf-187 (dexrazoxane)
68 | d1qy5a_ |
| not modelled | 97.4 | 22 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Heat shock protein 90, HSP90, N-terminal domain
69 | d1s14a_ |
| not modelled | 97.3 | 18 | Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain
70 | c3lnuA_ |
| not modelled | 97.2 | 15 | PDB header:isomerase Chain: A: PDB Molecule:topoisomerase iv subunit b; PDBTitle: crystal structure of pare subunit
71 | c2o1uA_ |
| not modelled | 96.6 | 22 | PDB header:chaperone Chain: A: PDB Molecule:endoplasmin; PDBTitle: structure of full length grp94 with amp-pnp bound
72 | d2c2aa1 |
| not modelled | 96.6 | 28 | Fold:ROP-like Superfamily:Homodimeric domain of signal transducing histidine kinase Family:Homodimeric domain of signal transducing histidine kinase
73 | c2rm8A_ |
| not modelled | 95.2 | 18 | PDB header:signaling protein Chain: A: PDB Molecule:sensory rhodopsin ii transducer; PDBTitle: the solution structure of phototactic transducer protein2 htrii linker region from natronomonas pharaonis
74 | c3cwvB_ |
| not modelled | 91.2 | 11 | PDB header:isomerase Chain: B: PDB Molecule:dna gyrase, b subunit, truncated; PDBTitle: crystal structure of b-subunit of the dna gyrase from myxococcus2 xanthus
75 | c3n0rA_ |
| not modelled | 70.4 | 15 | PDB header:signaling protein Chain: A: PDB Molecule:response regulator; PDBTitle: structure of the phyr stress response regulator at 1.25 angstrom2 resolution
76 | c3lmmA_ |
| not modelled | 57.3 | 15 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the dip2311 protein from2 corynebacterium diphtheriae, northeast structural genomics3 consortium target cdr35
77 | d1g0oa_ |
| not modelled | 46.7 | 21 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
78 | c3o38D_ |
| not modelled | 43.8 | 21 | PDB header:oxidoreductase Chain: D: PDB Molecule:short chain dehydrogenase; PDBTitle: crystal structure of a short chain dehydrogenase from mycobacterium2 smegmatis
79 | d2o23a1 |
| not modelled | 39.9 | 28 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
80 | c3s8mA_ |
| not modelled | 39.0 | 25 | PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-acp reductase; PDBTitle: the crystal structure of fabv
81 | d1zema1 |
| not modelled | 36.6 | 24 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
82 | c2zpaB_ |
| not modelled | 34.4 | 19 | PDB header:transferase Chain: B: PDB Molecule:uncharacterized protein ypfi; PDBTitle: crystal structure of trna(met) cytidine acetyltransferase
83 | c3gdfA_ |
| not modelled | 33.8 | 26 | PDB header:oxidoreductase Chain: A: PDB Molecule:probable nadp-dependent mannitol dehydrogenase; PDBTitle: crystal structure of the nadp-dependent mannitol dehydrogenase from2 cladosporium herbarum.
84 | c3k31B_ |
| not modelled | 32.4 | 14 | PDB header:oxidoreductase Chain: B: PDB Molecule:enoyl-(acyl-carrier-protein) reductase; PDBTitle: crystal structure of eonyl-(acyl-carrier-protein) reductase from2 anaplasma phagocytophilum in complex with nad at 1.9a resolution
85 | c2z1nA_ |
| not modelled | 31.8 | 28 | PDB header:oxidoreductase Chain: A: PDB Molecule:dehydrogenase; PDBTitle: crystal structure of ape0912 from aeropyrum pernix k1
86 | d1oaaa_ |
| not modelled | 30.7 | 19 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
87 | d1spxa_ |
| not modelled | 29.9 | 24 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
88 | d2h7ma1 |
| not modelled | 28.7 | 8 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
89 | c3ctmH_ |
| not modelled | 28.7 | 25 | PDB header:oxidoreductase Chain: H: PDB Molecule:carbonyl reductase; PDBTitle: crystal structure of a carbonyl reductase from candida2 parapsilosis with anti-prelog stereo-specificity
90 | c2o2sA_ |
| not modelled | 28.6 | 38 | PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-acyl carrier reductase; PDBTitle: the structure of t. gondii enoyl acyl carrier protein reductase in2 complex with nad and triclosan
91 | d1y5ma1 |
| not modelled | 28.3 | 20 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
92 | d1qsga_ |
| not modelled | 27.0 | 6 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
93 | c3gr6A_ |
| not modelled | 27.0 | 4 | PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh]; PDBTitle: crystal structure of the staphylococcus aureus enoyl-acyl2 carrier protein reductase (fabi) in complex with nadp and3 triclosan
94 | d1d7oa_ |
| not modelled | 25.9 | 29 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
95 | c3uf0A_ |
| not modelled | 25.8 | 36 | PDB header:oxidoreductase Chain: A: PDB Molecule:short-chain dehydrogenase/reductase sdr; PDBTitle: crystal structure of a putative nad(p) dependent gluconate 5-2 dehydrogenase from beutenbergia cavernae(efi target efi-502044) with3 bound nadp (low occupancy)
96 | c2p68A_ |
| not modelled | 25.7 | 32 | PDB header:oxidoreductase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase; PDBTitle: crystal structure of aq_1716 from aquifex aeolicus vf5
97 | d1gz6a_ |
| not modelled | 25.6 | 33 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
98 | c3rd5A_ |
| not modelled | 25.3 | 27 | PDB header:oxidoreductase Chain: A: PDB Molecule:mypaa.01249.c; PDBTitle: crystal structure of a putative uncharacterized protein from2 mycobacterium paratuberculosis
99 | c3qivA_ |
| not modelled | 25.0 | 29 | PDB header:oxidoreductase Chain: A: PDB Molecule:short-chain dehydrogenase or 3-oxoacyl-[acyl-carrier- PDBTitle: crystal structure of a putative short-chain dehydrogenase or 3-2 oxoacyl-[acyl-carrier-protein] reductase from mycobacterium3 paratuberculosis atcc baa-968 / k-10
100 | c3t6oA_ |
| not modelled | 25.0 | 11 | PDB header:transport protein Chain: A: PDB Molecule:sulfate transporter/antisigma-factor antagonist stas; PDBTitle: the structure of an anti-sigma-factor antagonist (stas) domain protein2 from planctomyces limnophilus.
101 | d1h5qa_ |
| not modelled | 24.8 | 36 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
102 | c3ftpD_ |
| not modelled | 24.6 | 28 | PDB header:oxidoreductase Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase; PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein)2 reductase from burkholderia pseudomallei at 2.05 a3 resolution
103 | c3gafF_ |
| not modelled | 23.5 | 29 | PDB header:oxidoreductase Chain: F: PDB Molecule:7-alpha-hydroxysteroid dehydrogenase; PDBTitle: 2.2a crystal structure of 7-alpha-hydroxysteroid2 dehydrogenase from brucella melitensis
104 | d2bela_ |
| not modelled | 23.4 | 26 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
105 | c3sx2F_ |
| not modelled | 23.3 | 21 | PDB header:oxidoreductase Chain: F: PDB Molecule:putative 3-ketoacyl-(acyl-carrier-protein) reductase; PDBTitle: crystal structure of a putative 3-ketoacyl-(acyl-carrier-protein)2 reductase from mycobacterium paratuberculosis in complex with nad
106 | c3imfA_ |
| not modelled | 23.3 | 25 | PDB header:oxidoreductase Chain: A: PDB Molecule:short chain dehydrogenase; PDBTitle: 1.99 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor'
107 | c3f5sA_ |
| not modelled | 23.0 | 25 | PDB header:oxidoreductase Chain: A: PDB Molecule:dehydrogenase; PDBTitle: crystal structure of putatitve short chain dehydrogenase from shigella2 flexneri 2a str. 301
108 | d1yxma1 |
| not modelled | 22.9 | 38 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
109 | c2p91A_ |
| not modelled | 22.6 | 9 | PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh]; PDBTitle: crystal structure of enoyl-[acyl-carrier-protein] reductase (nadh)2 from aquifex aeolicus vf5
110 | c2jahB_ |
| not modelled | 22.4 | 28 | PDB header:oxidoreductase Chain: B: PDB Molecule:clavulanic acid dehydrogenase; PDBTitle: biochemical and structural analysis of the clavulanic acid2 dehydeogenase (cad) from streptomyces clavuligerus
111 | c3pxxE_ |
| not modelled | 22.3 | 18 | PDB header:oxidoreductase Chain: E: PDB Molecule:carveol dehydrogenase; PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium avium2 bound to nicotinamide adenine dinucleotide
112 | c3i1jB_ |
| not modelled | 22.2 | 24 | PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase, short chain PDBTitle: structure of a putative short chain dehydrogenase from2 pseudomonas syringae
113 | c2vz8B_ |
| not modelled | 22.0 | 27 | PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase; PDBTitle: crystal structure of mammalian fatty acid synthase
114 | c3f9iB_ |
| not modelled | 21.9 | 28 | PDB header:oxidoreductase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase; PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase2 rickettsia prowazekii
115 | d1efub3 |
| not modelled | 21.8 | 16 | Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:TS-N domain
116 | c3ek2D_ |
| not modelled | 21.8 | 8 | PDB header:oxidoreductase Chain: D: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh); PDBTitle: crystal structure of eonyl-(acyl carrier protein) reductase2 from burkholderia pseudomallei 1719b
117 | d1ulsa_ |
| not modelled | 21.8 | 20 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
118 | c3afnC_ |
| not modelled | 21.7 | 33 | PDB header:oxidoreductase Chain: C: PDB Molecule:carbonyl reductase; PDBTitle: crystal structure of aldose reductase a1-r complexed with nadp
119 | d2a4ka1 |
| not modelled | 21.5 | 20 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
120 | c3ai3A_ |
| not modelled | 21.4 | 29 | PDB header:oxidoreductase Chain: A: PDB Molecule:nadph-sorbose reductase; PDBTitle: the crystal structure of l-sorbose reductase from gluconobacter2 frateurii complexed with nadph and l-sorbose

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0