Phyre 2 Results for P76280

Email | l.a.kelley@imperial.ac.uk
Description | P76280
Date | Thu Jan 5 12:21:33 GMT 2012
Unique Job ID | 00e69d2344ae1a6c

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c2vhiG_ |
|  | 100.0 | 18 | PDB header:hydrolase Chain: G: PDB Molecule:cg3027-pa; PDBTitle: crystal structure of a pyrimidine degrading enzyme from2 drosophila melanogaster
2 | c2e2kC_ |
|  | 100.0 | 12 | PDB header:hydrolase Chain: C: PDB Molecule:formamidase; PDBTitle: helicobacter pylori formamidase amif contains a fine-tuned cysteine-2 glutamate-lysine catalytic triad
3 | c2e11B_ |
|  | 100.0 | 15 | PDB header:hydrolase Chain: B: PDB Molecule:hydrolase; PDBTitle: the crystal structure of xc1258 from xanthomonas campestris: a cn-2 hydrolase superfamily protein with an arsenic adduct in the active3 site
4 | c1emsB_ |
|  | 100.0 | 13 | PDB header:antitumor protein Chain: B: PDB Molecule:nit-fragile histidine triad fusion protein; PDBTitle: crystal structure of the c. elegans nitfhit protein
5 | c2plqA_ |
|  | 100.0 | 18 | PDB header:hydrolase Chain: A: PDB Molecule:aliphatic amidase; PDBTitle: crystal structure of the amidase from geobacillus pallidus rapc8
6 | c2w1vA_ |
|  | 100.0 | 16 | PDB header:hydrolase Chain: A: PDB Molecule:nitrilase homolog 2; PDBTitle: crystal structure of mouse nitrilase-2 at 1.4a resolution
7 | d1uf5a_ |
|  | 100.0 | 18 | Fold:Carbon-nitrogen hydrolase Superfamily:Carbon-nitrogen hydrolase Family:Carbamilase
8 | c3dlaD_ |
|  | 100.0 | 21 | PDB header:ligase Chain: D: PDB Molecule:glutamine-dependent nad(+) synthetase; PDBTitle: x-ray crystal structure of glutamine-dependent nad+ synthetase from2 mycobacterium tuberculosis bound to naad+ and don
9 | c3hkxA_ |
|  | 100.0 | 17 | PDB header:hydrolase Chain: A: PDB Molecule:amidase; PDBTitle: crystal structure analysis of an amidase from nesterenkonia sp.
10 | d1f89a_ |
|  | 100.0 | 15 | Fold:Carbon-nitrogen hydrolase Superfamily:Carbon-nitrogen hydrolase Family:Nitrilase
11 | d1emsa2 |
|  | 100.0 | 13 | Fold:Carbon-nitrogen hydrolase Superfamily:Carbon-nitrogen hydrolase Family:Nitrilase
12 | c3n05B_ |
|  | 100.0 | 16 | PDB header:ligase Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: crystal structure of nh3-dependent nad+ synthetase from streptomyces2 avermitilis
13 | d1j31a_ |
|  | 100.0 | 18 | Fold:Carbon-nitrogen hydrolase Superfamily:Carbon-nitrogen hydrolase Family:Carbamilase
14 | c3ilvA_ |
|  | 100.0 | 17 | PDB header:ligase Chain: A: PDB Molecule:glutamine-dependent nad(+) synthetase; PDBTitle: crystal structure of a glutamine-dependent nad(+) synthetase2 from cytophaga hutchinsonii
15 | d1d9ea_ |
|  | 74.3 | 12 | Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase
16 | d1uf3a_ |
|  | 74.2 | 11 | Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TT1561-like
17 | c3stgA_ |
|  | 67.0 | 9 | PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of a58p, del(n59), and loop 7 truncated mutant of 3-2 deoxy-d-manno-octulosonate 8-phosphate synthase (kdo8ps) from3 neisseria meningitidis
18 | d1o60a_ |
|  | 66.9 | 11 | Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase
19 | c3dx5A_ |
|  | 62.5 | 4 | PDB header:lyase Chain: A: PDB Molecule:uncharacterized protein asbf; PDBTitle: crystal structure of the probable 3-dhs dehydratase asbf involved in2 the petrobactin synthesis from bacillus anthracis
20 | c3sz8D_ |
|  | 57.8 | 13 | PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei
21 | c2qw5B_ |
| not modelled | 57.1 | 14 | PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase-like tim barrel; PDBTitle: crystal structure of a putative sugar phosphate isomerase/epimerase2 (ava4194) from anabaena variabilis atcc 29413 at 1.78 a resolution
22 | c3qxbB_ |
| not modelled | 56.9 | 13 | PDB header:isomerase Chain: B: PDB Molecule:putative xylose isomerase; PDBTitle: crystal structure of a putative xylose isomerase (yp_426450.1) from2 rhodospirillum rubrum atcc 11170 at 1.90 a resolution
23 | d1vlia2 |
| not modelled | 53.8 | 9 | Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like
24 | c1vliA_ |
| not modelled | 50.3 | 9 | PDB header:biosynthetic protein Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse; PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution
25 | d2zdra2 |
| not modelled | 49.5 | 11 | Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like
26 | c2ou4C_ |
| not modelled | 47.5 | 3 | PDB header:isomerase Chain: C: PDB Molecule:d-tagatose 3-epimerase; PDBTitle: crystal structure of d-tagatose 3-epimerase from2 pseudomonas cichorii
27 | d1yx1a1 |
| not modelled | 47.0 | 14 | Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:KguE-like
28 | d1i60a_ |
| not modelled | 46.2 | 11 | Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:IolI-like
29 | c3pnxF_ |
| not modelled | 45.4 | 8 | PDB header:transferase Chain: F: PDB Molecule:putative sulfurtransferase dsre; PDBTitle: crystal structure of a putative sulfurtransferase dsre (swol_2425)2 from syntrophomonas wolfei str. goettingen at 1.92 a resolution
30 | c2ei9A_ |
| not modelled | 44.9 | 6 | PDB header:gene regulation Chain: A: PDB Molecule:non-ltr retrotransposon r1bmks orf2 protein; PDBTitle: crystal structure of r1bm endonuclease domain
31 | d2vgna3 |
| not modelled | 41.7 | 22 | Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:ERF1/Dom34 C-terminal domain-like
32 | c3s5oA_ |
| not modelled | 41.2 | 15 | PDB header:lyase Chain: A: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase, mitochondrial; PDBTitle: crystal structure of human 4-hydroxy-2-oxoglutarate aldolase bound to2 pyruvate
33 | c1xuzA_ |
| not modelled | 39.2 | 13 | PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol
34 | d1oi7a1 |
| not modelled | 39.0 | 19 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain
35 | d1wdua_ |
| not modelled | 38.7 | 7 | Fold:DNase I-like Superfamily:DNase I-like Family:DNase I-like
36 | d2nu7a1 |
| not modelled | 34.6 | 5 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain
37 | c2r94B_ |
| not modelled | 31.8 | 6 | PDB header:lyase Chain: B: PDB Molecule:2-keto-3-deoxy-(6-phospho-)gluconate aldolase; PDBTitle: crystal structure of kd(p)ga from t.tenax
38 | c2zdsB_ |
| not modelled | 31.7 | 14 | PDB header:dna binding protein Chain: B: PDB Molecule:putative dna-binding protein; PDBTitle: crystal structure of sco6571 from streptomyces coelicolor2 a3(2)
39 | c3qfnA_ |
| not modelled | 30.8 | 4 | PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of streptococcal asymmetric ap4a hydrolase and2 phosphodiesterase spr1479/saph in complex with inorganic phosphate
40 | c3ngfA_ |
| not modelled | 29.4 | 12 | PDB header:isomerase Chain: A: PDB Molecule:ap endonuclease, family 2; PDBTitle: crystal structure of ap endonuclease, family 2 from brucella2 melitensis
41 | c3bi8A_ |
| not modelled | 28.8 | 16 | PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of dihydrodipicolinate synthase from clostridium2 botulinum
42 | c3ju2A_ |
| not modelled | 28.0 | 11 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein smc04130; PDBTitle: crystal structure of protein smc04130 from sinorhizobium meliloti 1021
43 | d1x52a1 |
| not modelled | 27.3 | 16 | Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:ERF1/Dom34 C-terminal domain-like
44 | d2yvta1 |
| not modelled | 25.9 | 27 | Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TT1561-like
45 | c1vs1B_ |
| not modelled | 25.2 | 20 | PDB header:transferase Chain: B: PDB Molecule:3-deoxy-7-phosphoheptulonate synthase; PDBTitle: crystal structure of 3-deoxy-d-arabino-heptulosonate-7-2 phosphate synthase (dahp synthase) from aeropyrum pernix3 in complex with mn2+ and pep
46 | d1w3ia_ |
| not modelled | 24.7 | 4 | Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase
47 | c3obyB_ |
| not modelled | 24.2 | 8 | PDB header:hydrolase Chain: B: PDB Molecule:protein pelota homolog; PDBTitle: crystal structure of archaeoglobus fulgidus pelota reveals inter-2 domain structural plasticity
48 | c1s3mA_ |
| not modelled | 23.8 | 0 | PDB header:phosphodiesterase Chain: A: PDB Molecule:hypothetical protein mj0936; PDBTitle: structural and functional characterization of a novel2 archaeal phosphodiesterase
49 | d1s3la_ |
| not modelled | 23.8 | 0 | Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like
50 | c3obwA_ |
| not modelled | 22.5 | 7 | PDB header:hydrolase Chain: A: PDB Molecule:protein pelota homolog; PDBTitle: crystal structure of two archaeal pelotas reveal inter-domain2 structural plasticity
51 | c3agjB_ |
| not modelled | 22.5 | 19 | PDB header:translation/hydrolase Chain: B: PDB Molecule:protein pelota homolog; PDBTitle: crystal structure of archaeal pelota and gtp-bound ef1 alpha complex
52 | c3agjD_ |
| not modelled | 22.5 | 19 | PDB header:translation/hydrolase Chain: D: PDB Molecule:protein pelota homolog; PDBTitle: crystal structure of archaeal pelota and gtp-bound ef1 alpha complex
53 | c3fkkA_ |
| not modelled | 21.4 | 11 | PDB header:lyase Chain: A: PDB Molecule:l-2-keto-3-deoxyarabonate dehydratase; PDBTitle: structure of l-2-keto-3-deoxyarabonate dehydratase
54 | c1su1A_ |
| not modelled | 20.0 | 14 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein yfce; PDBTitle: structural and biochemical characterization of yfce, a2 phosphoesterase from e. coli
55 | d1su1a_ |
| not modelled | 20.0 | 14 | Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like
56 | c3kwsB_ |
| not modelled | 19.6 | 9 | PDB header:isomerase Chain: B: PDB Molecule:putative sugar isomerase; PDBTitle: crystal structure of putative sugar isomerase (yp_001305149.1) from2 parabacteroides distasonis atcc 8503 at 1.68 a resolution
57 | c2nuxB_ |
| not modelled | 19.4 | 13 | PDB header:lyase Chain: B: PDB Molecule:2-keto-3-deoxygluconate/2-keto-3-deoxy-6-phospho gluconate PDBTitle: 2-keto-3-deoxygluconate aldolase from sulfolobus acidocaldarius,2 native structure in p6522 at 2.5 a resolution
58 | c2j63B_ |
| not modelled | 19.4 | 18 | PDB header:lyase Chain: B: PDB Molecule:ap-endonuclease; PDBTitle: crystal structure of ap endonuclease lmap from leishmania2 major
59 | c3pg8B_ |
| not modelled | 19.2 | 17 | PDB header:transferase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima
60 | c3cnyA_ |
| not modelled | 18.8 | 5 | PDB header:biosynthetic protein Chain: A: PDB Molecule:inositol catabolism protein iole; PDBTitle: crystal structure of a putative inositol catabolism protein iole2 (iole, lp_3607) from lactobacillus plantarum wcfs1 at 1.85 a3 resolution
61 | c3p94A_ |
| not modelled | 18.7 | 12 | PDB header:hydrolase Chain: A: PDB Molecule:gdsl-like lipase; PDBTitle: crystal structure of a gdsl-like lipase (bdi_0976) from2 parabacteroides distasonis atcc 8503 at 1.93 a resolution
62 | c1zcoA_ |
| not modelled | 18.6 | 15 | PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphoheptonate aldolase; PDBTitle: crystal structure of pyrococcus furiosus 3-deoxy-d-arabino-2 heptulosonate 7-phosphate synthase
63 | c2vyeA_ |
| not modelled | 18.5 | 16 | PDB header:hydrolase Chain: A: PDB Molecule:replicative dna helicase; PDBTitle: crystal structure of the dnac-ssdna complex
64 | d1sgva1 |
| not modelled | 18.4 | 19 | Fold:PUA domain-like Superfamily:PUA domain-like Family:PUA domain
65 | c2zsmA_ |
| not modelled | 18.4 | 17 | PDB header:isomerase Chain: A: PDB Molecule:glutamate-1-semialdehyde 2,1-aminomutase; PDBTitle: crystal structure of glutamate-1-semialdehyde 2,1-2 aminomutase from aeropyrum pernix, hexagonal form
66 | c2hk1D_ |
| not modelled | 18.2 | 12 | PDB header:isomerase Chain: D: PDB Molecule:d-psicose 3-epimerase; PDBTitle: crystal structure of d-psicose 3-epimerase (dpease) in the presence of2 d-fructose
67 | d2csua1 |
| not modelled | 18.1 | 11 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain
68 | c2vgmA_ |
| not modelled | 17.0 | 22 | PDB header:cell cycle Chain: A: PDB Molecule:dom34; PDBTitle: structure of yeast dom34 : a protein related to translation2 termination factor erf1 and involved in no-go decay.
69 | c3dmyA_ |
| not modelled | 16.6 | 13 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:protein fdra; PDBTitle: crystal structure of a predicated acyl-coa synthetase from e.coli
70 | c3noeA_ |
| not modelled | 16.3 | 12 | PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from pseudomonas2 aeruginosa
71 | c3e96B_ |
| not modelled | 15.9 | 8 | PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 bacillus clausii
72 | c2hnhA_ |
| not modelled | 15.9 | 25 | PDB header:transferase Chain: A: PDB Molecule:dna polymerase iii alpha subunit; PDBTitle: crystal structure of the catalytic alpha subunit of e. coli2 replicative dna polymerase iii
73 | d1q7ra_ |
| not modelled | 15.7 | 24 | Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT)
74 | d1iuka_ |
| not modelled | 15.7 | 9 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain
75 | c3l44A_ |
| not modelled | 15.6 | 17 | PDB header:isomerase Chain: A: PDB Molecule:glutamate-1-semialdehyde 2,1-aminomutase 1; PDBTitle: crystal structure of bacillus anthracis heml-1, glutamate semialdehyde2 aminotransferase
76 | c3bleA_ |
| not modelled | 15.2 | 11 | PDB header:transferase Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans; PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate
77 | c3na8A_ |
| not modelled | 15.0 | 8 | PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of a putative dihydrodipicolinate synthetase from2 pseudomonas aeruginosa
78 | c3rqzC_ |
| not modelled | 14.8 | 6 | PDB header:hydrolase Chain: C: PDB Molecule:metallophosphoesterase; PDBTitle: crystal structure of metallophosphoesterase from sphaerobacter2 thermophilus
79 | d2gsaa_ |
| not modelled | 14.2 | 11 | Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:GABA-aminotransferase-like
80 | c3g8rA_ |
| not modelled | 14.2 | 11 | PDB header:biosynthetic protein Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e; PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472
81 | c3si9B_ |
| not modelled | 14.1 | 12 | PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from bartonella2 henselae
82 | c3fluD_ |
| not modelled | 14.0 | 10 | PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from the pathogen2 neisseria meningitidis
83 | c3pueA_ |
| not modelled | 14.0 | 16 | PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of the complex of dhydrodipicolinate synthase from2 acinetobacter baumannii with lysine at 2.6a resolution
84 | c2o14A_ |
| not modelled | 13.9 | 9 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein yxim; PDBTitle: x-ray crystal structure of protein yxim_bacsu from bacillus2 subtilis. northeast structural genomics consortium target3 sr595
85 | c3t4cD_ |
| not modelled | 13.8 | 16 | PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 1; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia ambifaria
86 | d1g5ba_ |
| not modelled | 13.8 | 10 | Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase
87 | d1f74a_ |
| not modelled | 13.7 | 8 | Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase
88 | c3fs2A_ |
| not modelled | 13.6 | 11 | PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate2 aldolase from bruciella melitensis at 1.85a resolution
89 | c3mcaB_ |
| not modelled | 13.6 | 22 | PDB header:translation regulation/hydrolase Chain: B: PDB Molecule:protein dom34; PDBTitle: structure of the dom34-hbs1 complex and implications for its role in2 no-go decay
90 | c2v9dB_ |
| not modelled | 13.3 | 10 | PDB header:lyase Chain: B: PDB Molecule:yage; PDBTitle: crystal structure of yage, a prophage protein belonging to2 the dihydrodipicolinic acid synthase family from e. coli3 k12
91 | d1k77a_ |
| not modelled | 12.9 | 10 | Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Hypothetical protein YgbM (EC1530)
92 | c1jvnB_ |
| not modelled | 12.8 | 14 | PDB header:transferase Chain: B: PDB Molecule:bifunctional histidine biosynthesis protein hishf; PDBTitle: crystal structure of imidazole glycerol phosphate synthase: a tunnel2 through a (beta/alpha)8 barrel joins two active sites
93 | c3eb2A_ |
| not modelled | 12.5 | 8 | PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 2.0a resolution
94 | c2cjdA_ |
| not modelled | 12.5 | 11 | PDB header:transferase Chain: A: PDB Molecule:l-lysine-epsilon aminotransferase; PDBTitle: lysine aminotransferase from m. tuberculosis in external2 aldimine form
95 | c3i4jC_ |
| not modelled | 12.5 | 8 | PDB header:transferase Chain: C: PDB Molecule:aminotransferase, class iii; PDBTitle: crystal structure of aminotransferase, class iii from2 deinococcus radiodurans
96 | c2cy8A_ |
| not modelled | 12.3 | 17 | PDB header:transferase Chain: A: PDB Molecule:d-phenylglycine aminotransferase; PDBTitle: crystal structure of d-phenylglycine aminotransferase (d-phgat) from2 pseudomonas strutzeri st-201
97 | d2qi2a3 |
| not modelled | 12.1 | 7 | Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:ERF1/Dom34 C-terminal domain-like
98 | d1xkya1 |
| not modelled | 12.0 | 6 | Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase
99 | c2yxgD_ |
| not modelled | 11.9 | 14 | PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihyrodipicolinate synthase (dapa)