3d2GO Protein Function Prediction Server

GO:0032553	ribonucleotide binding	0.13
GO:0032555	purine ribonucleotide binding	0.13
GO:0006810	transport	0.13
GO:0017076	purine nucleotide binding	0.13
GO:0005488	binding	0.12
GO:0000166	nucleotide binding	0.12
GO:0005622	intracellular	0.11
GO:0015031	protein transport	0.10
GO:0006886	intracellular protein transport	0.09
GO:0005524	ATP binding	0.09
GO:0005794	Golgi apparatus	0.09
GO:0016192	vesicle-mediated transport	0.09
GO:0005768	endosome	0.09
GO:0010008	endosome membrane	0.09
GO:0016775	phosphotransferase activity, nitrogenous group as acceptor	0.09
GO:0005887	integral to plasma membrane	0.09
GO:0044431	Golgi apparatus part	0.08
GO:0030117	membrane coat	0.08
GO:0030131	clathrin adaptor complex	0.08
GO:0008798	beta-aspartyl-peptidase activity	0.08
GO:0006509	membrane protein ectodomain proteolysis	0.08
GO:0008242	omega peptidase activity	0.08
GO:0008238	exopeptidase activity	0.08
GO:0005102	receptor binding	0.08
GO:0006508	proteolysis	0.08
GO:0004672	protein kinase activity	0.08
GO:0016773	phosphotransferase activity, alcohol group as acceptor	0.08
GO:0060089	molecular transducer activity	0.08
GO:0070011	peptidase activity, acting on L-amino acid peptides	0.07
GO:0008233	peptidase activity	0.07
GO:0007165	signal transduction	0.07
GO:0016301	kinase activity	0.06
GO:0009615	response to virus	0.06
GO:0018106	peptidyl-histidine phosphorylation	0.06
GO:0000155	two-component sensor activity	0.06
GO:0005126	cytokine receptor binding	0.06
GO:0016310	phosphorylation	0.06
GO:0006928	cell motion	0.06
GO:0004673	protein histidine kinase activity	0.06
GO:0000160	two-component signal transduction system (phosphorelay)	0.06
GO:0005179	hormone activity	0.06
GO:0005125	cytokine activity	0.06
GO:0006952	defense response	0.06
GO:0006935	chemotaxis	0.06
GO:0004871	signal transducer activity	0.05
GO:0016740	transferase activity	0.05
GO:0043211	carbohydrate-transporting ATPase activity	0.05
GO:0019866	organelle inner membrane	0.05
GO:0015608	carbohydrate-importing ATPase activity	0.05
GO:0009310	amine catabolic process	0.05
GO:0051188	cofactor biosynthetic process	0.05
GO:0051187	cofactor catabolic process	0.05
GO:0043284	biopolymer biosynthetic process	0.05
GO:0006080	substituted mannan metabolic process	0.05
GO:0044272	sulfur compound biosynthetic process	0.05
GO:0044270	nitrogen compound catabolic process	0.05
GO:0009109	coenzyme catabolic process	0.05
GO:0006732	coenzyme metabolic process	0.05
GO:0042398	cellular amino acid derivative biosynthetic process	0.05
GO:0044237	cellular metabolic process	0.05
GO:0000267	cell fraction	0.05
GO:0043212	carbohydrate-exporting ATPase activity	0.05
GO:0051186	cofactor metabolic process	0.05
GO:0030798	trans-aconitate 2-methyltransferase activity	0.05
GO:0015144	carbohydrate transmembrane transporter activity	0.05
GO:0043492	ATPase activity, coupled to movement of substances	0.05
GO:0042626	ATPase activity, coupled to transmembrane movement of substances	0.05
GO:0043231	intracellular membrane-bounded organelle	0.05
GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	0.05
GO:0015399	primary active transmembrane transporter activity	0.05
GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.05
GO:0042623	ATPase activity, coupled	0.05
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	0.05
GO:0022804	active transmembrane transporter activity	0.05
GO:0016887	ATPase activity	0.05
GO:0008168	methyltransferase activity	0.05
GO:0016741	transferase activity, transferring one-carbon groups	0.05
GO:0022891	substrate-specific transmembrane transporter activity	0.05
GO:0022857	transmembrane transporter activity	0.05
GO:0017111	nucleoside-triphosphatase activity	0.05
GO:0016462	pyrophosphatase activity	0.04
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.04
GO:0016817	hydrolase activity, acting on acid anhydrides	0.04
GO:0016772	transferase activity, transferring phosphorus-containing groups	0.04
GO:0022892	substrate-specific transporter activity	0.04
GO:0005215	transporter activity	0.04
GO:0016787	hydrolase activity	0.04
GO:0003824	catalytic activity	0.03
GO:0003673	Gene_Ontology	0.00
GO:0003674	molecular_function	0.00

Full Details

Full topology search (3D-BLAST)

Full topology search (MAMMOTH)

Sequence Methods

GO	Description	Minimum E-value	Number of hits	Top PDB hit
GO:0010008	endosome membrane	2e-14	2	1UJK
GO:0016021	integral to membrane	2e-14	24	1UJK
GO:0016787	hydrolase activity	2e-14	3	1UJK
GO:0015031	protein transport	2e-14	6	1UJK
GO:0008798	beta-aspartyl-peptidase activity	2e-14	1	1UJK
GO:0005887	integral to plasma membrane	2e-14	2	1UJK
GO:0030131	clathrin adaptor complex	2e-14	1	1UJK
GO:0005768	endosome	2e-14	3	1UJK
GO:0016192	vesicle-mediated transport	2e-14	3	1UJK
GO:0006810	transport	2e-14	20	1UJK
GO:0030117	membrane coat	2e-14	1	1UJK
GO:0005794	Golgi apparatus	2e-14	4	1UJK
GO:0003674	molecular_function	2e-14	1	1UJK
GO:0016020	membrane	2e-14	41	1UJK
GO:0005622	intracellular	2e-14	3	1UJK
GO:0005515	protein binding	2e-14	30	1UJK
GO:0044431	Golgi apparatus part	2e-14	1	1UJK
GO:0006886	intracellular protein transport	2e-14	5	1UJK
GO:0008233	peptidase activity	2e-14	2	1UJK
GO:0006509	membrane protein ectodomain proteolysis	2e-14	1	1UJK
GO:0006508	proteolysis	2e-14	2	1UJK

GO	Description	Max -ln(E-value)	Number of hits	Top PDB hit
GO:0018106	peptidyl-histidine phosphorylation	9.336	1	1TQG
GO:0006935	chemotaxis	9.336	1	1TQG
GO:0005737	cytoplasm	9.336	9	1TQG
GO:0007165	signal transduction	9.336	2	1TQG
GO:0016301	kinase activity	9.336	2	1TQG
GO:0000160	two-component signal transduction system (phosphorelay)	9.336	1	1TQG
GO:0000155	two-component sensor activity	9.336	1	1TQG
GO:0005622	intracellular	9.336	2	1TQG
GO:0006928	cell motion	9.336	1	1TQG
GO:0016772	transferase activity, transferring phosphorus-containing groups	9.336	1	1TQG
GO:0016310	phosphorylation	9.336	1	1TQG
GO:0005515	protein binding	9.336	7	1TQG
GO:0016740	transferase activity	9.336	3	1TQG
GO:0004673	protein histidine kinase activity	9.336	1	1TQG
GO:0005524	ATP binding	9.336	4	1TQG
GO:0004871	signal transducer activity	9.336	1	1TQG
GO:0005126	hematopoietin/interferon-class (D200-domain) cytokine receptor binding	9.064	1	1B5L
GO:0006952	defense response	9.064	1	1B5L
GO:0009615	response to virus	9.064	1	1B5L
GO:0005179	hormone activity	9.064	1	1B5L
GO:0005125	cytokine activity	9.064	1	1B5L

GO	Description	Confidence
GO:0030798	trans-aconitate 2-methyltransferase activity	0.947
GO:0043231	intracellular membrane-bound organelle	0.891
GO:0005488	binding	0.809
GO:0051186	cofactor metabolism	0.763
GO:0043212	carbohydrate-exporting ATPase activity	0.76
GO:0000267	cell fraction	0.757
GO:0042398	amino acid derivative biosynthesis	0.75
GO:0042623	ATPase activity, coupled	0.728
GO:0006732	coenzyme metabolism	0.719
GO:0009109	coenzyme catabolism	0.706
GO:0044270	nitrogen compound catabolism	0.704
GO:0044272	sulfur compound biosynthesis	0.688
GO:0043284	biopolymer biosynthesis	0.684
GO:0006080	mannan metabolism	0.68
GO:0044237	cellular metabolism	0.677
GO:0051187	cofactor catabolism	0.671
GO:0015608	carbohydrate-importing ATPase activity	0.665
GO:0009310	amine catabolism	0.665
GO:0051188	cofactor biosynthesis	0.664
GO:0019866	inner membrane	0.661
GO:0043211	carbohydrate-transporting ATPase activity	0.661

Amino Acid Sequence
Index	.	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.
Query Sequence	M	N	D	I	F	F	G	L	M	M	L	G	G	F	F	V	L	G	I	G	M	W	A	L	G	Q	W	L	R	R	K	G	F	G	P	Q	L	D	A	L	D	K	Q	Y	T	A	L	Q	H	R	V	N	R	L	A	L	P	A	A	A	H	F	Y	G	G	M	G	M	L	N	R	M	P	L	F	G	S	K	N	Q	V	V
Index	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.
Query Sequence	L	V	E	R	V	R	M	A	I	L	Q	M	E	E	E	E	R	Q	R	G	R	G	I	N	R

© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley