HHsearch 1.5 NAME c9zmyA_ FAM FILE c9zmyA_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9zmyA_.a3m DATE Sat Jan 24 09:59:52 2026 LENG 114 match states, 114 columns in multiple alignment FILT 50 out of 52 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 5.9 EVD 0.3856 -2.2172 SEQ >ss_pred CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH HHHHHHHHHHHHHC >ss_conf 9409999999952898999999999999620056576899999999861799989999999999999999986159989999999983999899999999 99999999999729 >Consensus xxxxxxxvxlinxlxxxkfxxLxxxIxxxlxxxxxxxfxxeexxklxxxxxlxxxdlxxiixxlsfilxxAaxxxxxxxxLxxeLxqlglpkexxxxxxx xwxxxgxxlxxxlr >c9zmyA_ SPSMKKAVSLINAIDTGRFPRLLTRILQKLHLKAESSFSEEEEEKLQAAFSLEKQDLHLVLETISFILEQAVYHNVKPAALQQQLENIHLRQDKAEAFVN TWSSMGQETVEKFR >UniRef50_A2FX49(7-117:189) HCaRG protein n=1 Tax=Trichomonas vaginalis RepID=A2FX49_TRIVA E=2e-08 s/c=0.55 id=21% cov=98% ---LSEALKIVEKIPQRPFAQLLRRLAIALKERDNIPFSEDEVQILLEQFKLTPTELESFFSACQYVLQQAACYSFNSEKTQMYASQCGVPDEIAECFSA VWDAEGEDLINALK >UniRef50_A0D746(5-116:222) Chromosome undetermined scaffold_4, whole genome shotgun sequence n=2 Tax=Paramecium tetraurelia RepID=A0D746_PARTE E=2e-17 s/c=0.81 id=22% cov=98% --NLQDAILNLNSLSIPRTEIVIGRIFSKPGQLYKDLFTEDEIKKFQNNLNIAEQQLANIVNAFTFVLMHVVAER-NLSQVEEVLAQNGMSQDHIEVFRQ QWIQYGNEYSIRIR >UniRef50_C3KJ90(17-122:199) COMM domain-containing protein 4 n=7 Tax=Chordata RepID=C3KJ90_ANOFI E=1e-21 s/c=0.97 id=20% cov=92% -------ISTLAKISSVKMKLLCAQVLKDLLG---DGIDYDKVTKLTADAKFESGDIKASVAVLSFIFSSAAKHDVDSESLSSELQQLGLPKEHTTGLCK SYEDKHSALQCKLR >UniRef50_Q05AV1(11-118:197) COMM domain-containing protein 6 n=4 Tax=Tetrapoda RepID=COMD6_XENLA E=6e-13 s/c=0.70 id=18% cov=95% ---FEKTGDLIKIVPPDLFAELCQQSVQHLQRQRSGVDCHAIFQSFQAvGVHISEDELRKIIRGMTALFSTAAKYNVTCEELLSMLIS-KLPKQILQVIR HVWNEEGKHLCE--- >UniRef50_A8P9M5(17-125:199) Putative uncharacterized protein n=1 Tax=Brugia malayi RepID=A8P9M5_BRUMA E=6e-12 s/c=0.66 id=24% cov=94% -------VEKIIQLGATKFIQISQHVLERMPDTVDvaDIFDTEEREKLRENLQIDlPTELSVFL-TISELWKNIAYSQPKLQPLLESLKEIGFDDEMRTA IVKVWSESGVTVSDQLR >UniRef50_B0ELQ0(15-122:198) COMM domain-containing protein, putative n=2 Tax=Entamoeba RepID=B0ELQ0_ENTDI E=1e-10 s/c=0.62 id=18% cov=85% -----KEIGTVQRLNNEEVKEISIEIINNMIKK--EGFNKKEFNSICERRKLTESDLRGIITTLRFILCSAAQYDISSERLLEEELEIGIDIEIAETISK IYE----------- >UniRef50_Q9GZQ3(31-129:224) COMM domain-containing protein 5 n=22 Tax=Euteleostomi RepID=COMD5_HUMAN E=1e-09 s/c=0.65 id=22% cov=85% -PEVAAMARLLGDLDRSTFRKLLKFVVSSLQGEDCR----EAVQRLGVSANLPEEQLGALLAGMHTLLQQALRlppTSLKPDTFRDQLQELCIPQDLVGD LASV------------- >UniRef50_C4WY15(10-123:171) ACYPI008394 protein n=2 Tax=Acyrthosiphon pisum RepID=C4WY15_ACYPI E=1e-08 s/c=0.53 id=25% cov=100% -PFFVSGLELLNNVDDKKFVRLVDKMIQDFEPNRLSSFSELELASMKKSLKLNNNQCQCLLNCLNQLLKEVISDVTKPLVLKNVLSTLfSLNGRKVELFC ECWSKNAEQVVSRLQ >UniRef50_Q6P4M4(18-112:199) COMM domain containing 7 n=2 Tax=Xenopus (Silurana) tropicalis RepID=Q6P4M4_XENTR E=0.0002 s/c=0.50 id=20% cov=82% ----------LQQLHSEQVSRLCSIIFGFLKGQKEQPHLHSQLDDFARINGISLGPLKSIVKSIFLILNDALKRNVSAEQLRNDLIGLGLDEEKASYFEH QW------------ # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * S 1 * * * * * * * * * * * * * * * 1603 576 * * * 1 0 * * * * * * 2746 0 0 P 2 2619 * * * * * * * 2886 * * * 511 * * * * * * * 2 0 * * * * * * 3488 0 0 S 3 * * * 3589 3402 * * * * * * 3229 * * 1442 1783 4135 * * * 3 0 * * * * * * 4355 0 0 M 4 * * * * 1313 * * 3337 * 1737 3992 * * * * * * 2881 * * 4 0 * * * * * * 4953 0 0 K 5 3970 * 3798 3763 * * * * 2628 4514 * 4007 * 2871 * 2403 4549 3711 * 3680 5 0 * * * * * * 4953 0 0 K 6 3293 * 2933 3831 * 4308 4868 * 1656 * * * * 4638 4191 2810 4128 * * * 6 0 * * * * * * 5191 0 0 A 7 1092 * * 3721 * 2223 * * * * 4060 * * * * 4314 2935 * * * 7 0 * * * * * * 5229 0 0 V 8 4597 * * * * 4411 * 1612 * 2723 * * * * * * * 1208 * * 8 0 * * * * * * 5692 0 0 S 9 3528 * 3370 2162 * 4365 * * 3412 3521 * 4734 * 4001 4584 2172 * * * * 9 0 * * * * * * 5772 0 0 L 10 * * * * * * * 2796 4422 1187 * 3500 * 4416 * * 2090 * * * 10 0 * * * * * * 5772 0 0 I 11 * * * * 4828 * * 1166 * 1420 4749 * * * * * * 3206 * * 11 0 * * * * * * 6015 0 0 N 12 3873 * 4797 3508 * 3839 * 4578 4796 * * 1196 * 3501 * 3328 4807 * * * 12 0 * * * * * * 6015 0 0 A 13 4023 * 4861 4993 * 4579 * 4796 1870 4804 * 4352 * 2756 2964 3022 4749 * * * 13 0 * * * * * * 6015 0 0 I 14 * * * * * * * 2023 * 987 3554 * * * * * * 2606 * * 14 0 * * * * * * 6015 0 0 D 15 4807 * 1906 3908 * 4578 4416 * * * * 3776 1767 * * 2792 5022 * * * 15 0 * * * * * * 6015 0 0 T 16 3611 * 3790 * * * * 3811 * * 5700 3691 3202 2994 3923 1808 3883 5357 * * 16 0 * * * * * * 6015 0 0 G 17 3885 * 2181 3501 * 4150 * 5537 3769 * * 4987 3215 * 4383 3828 3939 2742 * * 17 0 * * * * * * 6015 0 0 R 18 * * * 4718 4889 * * 4647 1130 3895 4778 * 4564 3697 2509 * 4938 * * * 18 51 4861 * 0 * * * 6180 1000 0 F 19 5006 * * * 1097 * * 3999 * 2414 3266 * * * * * 4731 3190 * * 19 0 * * * * * * 6181 0 0 P 20 2108 * * 3862 4957 * * 4753 1814 * * 4348 3686 5122 3646 3955 * 4453 * * 20 0 * * * * * * 6181 0 0 R 21 4260 * * 2164 * * * 4763 2825 2034 * * * 3068 2888 5583 * 5186 * * 21 0 * * * * * * 6185 0 0 L 22 * * * * * * * 2553 * 706 4060 * * * * * 3862 3509 * * 22 0 * * * * * * 6185 0 0 L 23 * 1749 * * * * * 4120 * 1333 * * * * * 3768 4399 2974 * * 23 0 * * * * * * 6185 0 0 T 24 3843 * 4514 3697 * 4074 * 3889 4089 * * 3466 * 2348 4587 3322 2549 5355 * * 24 0 * * * * * * 6185 0 0 R 25 5157 * * 3754 5008 * 3380 4557 3745 * * * * 1891 1751 * 4770 * * 4309 25 0 * * * * * * 6185 0 0 I 26 4611 * * * * * * 870 * 3844 4514 * * * * 5032 * 1900 * * 26 0 * * * * * * 6185 0 0 L 27 3274 5020 * * 2984 4740 * 2116 * 1668 * * * * * * * 2675 * * 27 0 * * * * * * 6185 0 0 Q 28 * * * 4767 * 4557 4611 4587 3181 3449 * 3949 * 1397 * 2933 5355 4770 * * 28 0 * * * * * * 6185 0 0 K 29 4587 5595 3740 5968 3646 * 2498 * 2276 4611 * 3516 * * 3555 2556 * * * * 29 41 * 5175 * * * * 6185 0 0 L 30 * * * * 3870 * 5520 3034 4950 902 3029 * 3864 * * * * * * 5104 30 117 * 3687 * * * 0 6153 0 1000 H 31 5037 * * 4371 * 3842 2896 4677 3495 2050 * 4210 4630 2190 * * 4861 * * * 31 0 * * * * * 0 6107 0 2446 L 32 * * 3668 3010 * 2713 2973 * 4691 3320 * 5064 4391 4693 3896 2947 5261 * * 4668 32 84 * 4152 * * 1741 513 6128 0 2446 K 33 * * 3605 3993 * 2992 * * 1751 4675 * 4397 * 2484 3787 4933 4686 5461 * * 33 153 4921 3881 0 * 771 1272 6165 1000 2130 A 34 3438 * 3028 3191 * * * 3490 4483 * * 2620 * * 3640 4009 3913 3336 * 3806 34 40 * 5189 * * * 0 6151 0 1962 E 35 * 4980 2552 1411 * 4707 * * 4673 4394 * 3227 4275 * 3821 3888 * * * * 35 152 4635 4063 1000 1000 511 1744 6132 1000 2076 S 36 4805 * 2890 2467 * 2230 * 3822 5542 * * 4420 5147 3739 3399 3342 * * * * 36 43 * 5100 * * 2061 395 6204 0 2172 S 37 3769 * 5150 5709 * 3820 * 2684 5294 3799 * * 3525 5874 * 2737 3561 2204 * * 37 0 * * * * 1172 846 6167 0 2502 F 38 * * 3046 * 797 * 4607 4241 * 4122 * 3568 * * * * * 4807 4970 * 38 32 * 5513 * * 983 1018 6195 0 1838 S 39 * 5066 2726 5101 * * * * * 3195 * 2304 * 6427 * 2162 2040 * * * 39 0 * * * * * 0 6215 0 1703 E 40 3086 * 4967 1556 4587 * 3844 4871 4943 * * * * 5186 * 2864 4963 5176 * 3215 40 0 * * * * 0 * 6215 0 1703 E 41 2811 * 2813 1106 * * * * 4110 3983 * 4828 * * 4991 3993 * * * * 41 0 * * * * * * 6161 0 0 E 42 5290 * * 1230 4991 * 4982 4100 2133 4384 * 5520 * 4036 * * 3873 * * * 42 0 * * * * * * 6161 0 0 E 43 3859 3153 * 2842 4045 * * 3076 5187 2478 * * * 5194 4437 3927 * 2699 * * 43 0 * * * * * * 6161 0 0 E 44 4019 * 2994 2089 5674 * * 6189 3448 4909 * 3605 * 2932 5523 4900 3835 4329 * 4998 44 0 * * * * * * 6161 0 0 K 45 * * 4698 5806 * * * 4015 841 * * * * * 2711 2845 * 4982 * * 45 0 * * * * * * 6161 0 0 L 46 * * * * 2995 * * 2474 * 777 4174 * * * * * 5477 * * 4920 46 46 4991 * 0 * * * 6161 1000 0 Q 47 4698 4931 * * * 4241 4828 * 4804 2648 5806 4982 * 1616 4995 5271 2490 4868 * * 47 150 3976 4828 0 * * * 6161 1390 0 A 48 2080 * * 2296 * * * * 3708 4478 * 4193 5130 5800 4636 3719 3271 3088 * * 48 42 5121 * 0 * * 0 6068 1000 1000 A 49 2906 * 2038 * * 2754 * 4636 * 4289 * 3553 * 4706 4882 2581 4085 * * * 49 73 4348 * 0 * * 0 6068 1123 1000 F 50 2169 * * * 2463 * * 3111 4899 1976 * 4636 * * 4882 4115 * 4037 * * 50 45 * 5033 * * * 0 6068 0 1000 S 51 4826 * 3420 5197 * 3278 5079 * 1442 * * 3459 5111 4923 4435 3202 4816 * * * 51 0 * * * * * 0 5985 0 1650 L 52 * * * * 2694 * * 1979 * 989 5125 * * * * * 4951 5206 * * 52 0 * * * * 1058 944 5997 0 1650 E 53 5128 * 2110 2923 * 4057 * 5176 * * * 2709 5253 * * 2853 2426 5923 * * 53 47 4973 * 0 * 0 * 6094 1000 1000 K 54 5642 * 3729 2706 * * 5046 4733 3396 3847 * 4810 3198 3631 * 2860 5270 2944 * * 54 0 * * * * * * 6116 0 0 Q 55 5340 * 4236 2815 * 2359 5109 * 3708 5354 * 2790 * 3182 * 3256 3382 * * * 55 0 * * * * * * 6138 0 0 D 56 3738 * 1440 1913 * 5873 4937 * * * * 4584 4815 2886 * 5120 * * * * 56 40 5202 * 1000 1000 * * 6138 1000 0 L 57 4407 4218 * * 5354 4890 * 3292 5758 1056 6009 * * * * 4937 * 2387 * * 57 0 * * * * * * 6138 0 0 H 58 3733 * * 3780 * 5252 5186 * 1671 * * 3160 * 2726 3747 4471 4386 4219 * * 58 0 * * * * * * 6138 0 0 L 59 2336 4767 5060 5022 * 2962 * 5182 3807 2267 * 4216 * * * 2728 4890 5015 * * 59 0 * * * * * * 6138 0 0 V 60 3741 4286 * * 3870 * * 2017 * 2237 4537 * * * * 4282 4647 2238 * * 60 0 * * * * * * 6138 0 0 L 61 5627 * * * 4663 * * 1705 * 1554 * * * * * * 5268 1904 * * 61 48 * 4931 * * * * 6054 0 0 E 62 1487 * 4588 2831 * * * 4912 5088 * * 2793 * 3462 3617 4589 5163 6300 * * 62 0 * * * * 0 * 5975 0 1000 T 63 1923 2937 * * 4970 2996 * 5484 * 4285 * * * * * 3535 1993 4739 * * 63 0 * * * * * * 6018 0 0 I 64 * 3487 4922 * 4146 * * 1817 * 1389 3682 * * * * 5940 * 4024 * * 64 0 * * * * * * 6018 0 0 S 65 5352 5494 * 3671 4044 * 3443 * * 6129 * 4233 * 4643 4377 1469 2536 * 4922 * 65 0 * * * * * * 6018 0 0 F 66 5466 * * 4981 836 * 4217 * * 3764 * * * 4263 * 5026 5264 * * 2742 66 0 * * * * * * 6018 0 0 I 67 5934 * * * 6302 * * 1015 * 1896 4308 * * * * * 4970 3383 * 5094 67 0 * * * * * * 6018 0 0 L 68 * 5338 * * 1797 * * 3938 * 1052 * * * * * * * 4173 4211 5026 68 18 * 6302 * * * * 6018 0 0 E 69 5892 4529 * 2326 5976 * * * 2528 6314 4138 5115 * 3455 3460 2683 3252 6625 * * 69 0 * * * * * 0 6009 0 1000 Q 70 * * 5115 4770 * * 4138 * 5412 4995 * 2332 4918 1814 * 2066 3879 * * * 70 0 * * * * * 0 6009 0 1000 A 71 463 * * * * * * 4929 * * * * * * * 3402 3645 3901 * * 71 0 * * * * * 0 6009 0 1000 V 72 860 * * 4929 * 4918 * 4770 * 3610 * * * * * 4786 3818 2668 * * 72 49 * 4918 * * * 0 6009 0 1000 Y 73 4083 3717 * 4890 4237 * * * 1790 * * * * 5167 2205 3944 * * * 2479 73 39 5222 * 1585 585 752 1300 5932 1000 1525 H 74 * * 4770 4138 3415 * 2290 * * * * 2794 * * 5115 3460 5258 5342 * 1768 74 0 * * * * * 0 6009 0 1000 N 75 3290 * 2293 * * 5116 * 5342 * 4220 * 1964 * 4071 4138 2800 6314 4115 * * 75 84 * 4138 * * * 0 6009 0 1000 V 76 3481 3408 * * 4527 * * 3589 * 2055 5878 * 4869 * * * 3473 1700 * * 76 0 * * * * 514 1738 5845 0 1847 K 77 * * 3251 3211 * 5793 * * 1926 * * 3012 4918 * * 1693 4661 * * * 77 0 * * * * * 0 6009 0 1000 P 78 2799 5454 4870 2970 * 4941 * 5237 * 3378 * * 1908 6107 * 2780 3799 * 5793 * 78 0 * * * * * 0 6009 0 1000 A 79 4640 * 2786 1758 * 5292 5852 * 5211 4771 * 3147 * 3563 5442 3440 3868 4980 * * 79 0 * * * * * 0 5990 0 1000 A 80 4995 * 2953 3319 * * * 3026 3973 * * 5374 4888 3761 5211 4357 3288 2130 * 6100 80 0 * * * * * 0 5990 0 1000 L 81 * * * * 3258 * * 4973 * 384 * * * * * * 4604 4151 * * 81 0 * * * * * 0 5990 0 1000 Q 82 4463 5953 * 2686 5470 4172 * 4112 4771 3298 5292 5977 * 3116 3873 2822 5852 2998 * * 82 0 * * * * * 0 5990 0 1000 Q 83 4219 * 3880 3018 * * * 4973 3658 4707 4604 2636 * 2634 4883 3006 3571 * * * 83 0 * * * * * 0 5990 0 1000 Q 84 5496 * 5100 1131 * * * * * * 5439 4951 * 2447 4884 3930 4413 3923 * 4604 84 0 * * * * * 0 5990 0 1000 L 85 4604 * * 5211 * * * 3949 * 323 4189 * * * * * * 6276 * * 85 70 4407 * 563 1630 * 0 5990 1725 1000 E 86 4151 * * 3177 * 4216 * 3520 3152 5211 * * * 1794 * 2908 3528 4497 * * 86 0 * * * * * 0 5990 0 1000 N 87 4463 * 4838 2522 * 5100 5211 5433 3618 * * 4525 * 1263 * 4539 4771 4475 * * 87 115 4216 5439 1000 1000 * 0 5990 1517 1000 I 88 * 3719 * * * * * 2527 * 918 * 4229 * * * 3273 5363 4640 * * 88 158 3269 * 392 2070 719 1349 5966 2456 1560 H 89 5292 5317 * 5657 * 702 4525 * 3130 * 5374 * * 5470 * 3868 4569 * * * 89 33 5470 * 1000 1000 * 0 5990 1000 1000 L 90 4474 * * * 3681 * * 2688 * 773 5094 * * * * * * 4604 3917 * 90 33 5455 * 0 * * 0 5990 1000 1000 R 91 * * 3475 4681 * 4973 5433 * * * * 3535 964 * 6037 2651 4553 * * * 91 0 * * * * * 0 5990 0 1000 Q 92 5442 * 2524 4273 * 4771 5494 5211 1331 * * * 6276 3002 4361 4307 4994 * * * 92 0 * * * * 0 * 5990 0 1000 D 93 4033 * 1865 1198 * 4526 4488 * * * * * * 5472 4781 4818 4433 * * * 93 0 * * * * * * 6026 0 0 K 94 3710 * * * * * 1290 3509 1985 5273 4985 4864 * * * 4622 4578 * * * 94 0 * * * * * * 6026 0 0 A 95 1642 3463 * * * 4570 * 3280 * 2943 * * * * 4985 4478 3444 2781 * * 95 0 * * * * * * 6026 0 0 E 96 2653 * 4929 1810 * 4711 * 6366 4197 * * * * 2418 5478 3508 3462 5059 * * 96 0 * * * * * * 6026 0 0 A 97 2019 3585 4319 * * 5302 * 4209 * 3445 5748 * * 3639 * 4025 4389 2237 * 5131 97 0 * * * * * * 6026 0 0 F 98 * * * * 1745 * * 2116 * 1558 4090 * * * * * * 3779 * * 98 0 * * * * * * 6026 0 0 V 99 3735 2043 * 5131 * 6020 4972 5748 5242 6305 * 5524 * 3260 2846 2845 5488 3034 * * 99 0 * * * * * * 6026 0 0 N 100 4669 * * 3531 * * 2715 * 1685 * * 4559 * 3647 2204 3806 * * * * 100 0 * * * * * * 6026 0 0 T 101 2920 4424 * * 5458 5278 * 5207 * 2867 * * * 3531 * 3677 3991 1392 * * 101 0 * * * * * * 5990 0 0 W 102 * * * * 3750 * * * * 4262 * * * * * * * * 733 1880 102 0 * * * * * * 6035 0 0 S 103 3987 * 3575 2427 * * * 3960 3535 5765 * 3400 * 4569 3805 2721 3207 5069 * * 103 40 * 5206 * * * * 6020 0 0 S 104 3051 * 2656 1755 * * * 5601 4025 * * 4858 * 3983 5348 4735 3089 3944 * * 104 0 * * * * * 0 5973 0 1000 M 105 * * * 3742 * 5306 2382 * 3294 5079 4628 2795 * 3135 * 3622 * * * 2344 105 0 * * * * * 0 5849 0 1000 G 106 2946 * * * * 1004 5198 * 3298 4573 * 5381 * 5183 4975 3828 * 4417 * * 106 0 * * * * 0 * 5849 0 1000 Q 107 3956 * * 2089 * * * * 2523 * * 2748 4997 3117 3991 3307 5227 4622 * * 107 0 * * * * * * 5734 0 0 E 108 3770 * 3434 2051 * 4649 3801 * 3801 * 4977 4042 3914 3095 * 3951 3857 * * * 108 0 * * * * * * 5749 0 0 T 109 * * * * * * * 2619 * 1340 * * * * * * 2872 2140 * 3667 109 0 * * * * * * 5749 0 0 V 110 * 4524 * * * * * 2774 4687 4067 4561 * * 3557 2405 3480 3453 2219 * * 110 0 * * * * * * 5629 0 0 E 111 5472 5860 3426 1494 * * * 3544 3669 * * 2944 * 3624 4687 3740 5442 * * * 111 0 * * * * * * 5629 0 0 K 112 3319 * * * 4655 * 3621 5044 1760 * * 4583 * 4371 2550 4565 3779 3695 * * 112 0 * * * * * * 5508 0 0 F 113 * * * * 1689 * * 3379 * 953 * * * * * * 5121 4373 * * 113 0 * * * * * * 5480 0 0 R 114 * * * * * * * * 1205 * * * * 3965 993 * * * * * 114 0 * * 0 * * * 5172 0 0 //