HHsearch 1.5 NAME c9ul1B_ FAM FILE c9ul1B_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9ul1B_.a3m DATE Sat Aug 16 17:58:45 2025 LENG 97 match states, 97 columns in multiple alignment FILT 103 out of 708 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 8.1 EVD 0.4459 -0.4409 SEQ >ss_pred CCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEEEEECCEEECCCCCEEEECCCCCEEEEEEEEEECCCCCEEEEEEECCCCCCCEEEEEECCC >ss_conf 9856799970586557873799999976657735999960759805654403753797199999999806658869999992668896399530489 >Consensus xxPPxvxixxxxxxxxgxxvtLxCxxxgfxPxxixixWxxxgxxlxxxxxxxxxxxdgtxsxxsxlxvxxxxxxxytCxVxHxxLxxpxxxxwxxxx >c9ul1B_ ARPPKVQVYSRHPAENGKPNYLNCYVSGFHPPQIEIDLLKNGEKMNAEQSDLSFSKDWSFYLLVHTEFTPNAVDQYSCRVKHVTLDKPKIVKWDRDH >UniRef50_P01867(4-98:404) Ig gamma-2B chain C region n=49 Tax=Eutheria RepID=IGG2B_MOUSE E=2e-06 s/c=0.56 id=17% cov=97% --PPSVYPLAPGCGDtTGSSVTLGCLVKGYFPESVTVTWNSGSLSSSVHTfPALLQSGLYTMSSSVTVPSSTWPSQTVTCSVAHPASSTTVDKKLEP-- >UniRef50_B0BMB6(365-469:487) LOC100145016 protein (Fragment) n=1 Tax=Xenopus (Silurana) tropicalis RepID=B0BMB6_XENTR E=5e-07 s/c=0.53 id=18% cov=94% -RPRMGEIIKPDTLIHGKEGRFQCKIWGYFPLCLELRWFRIEVGVRERiplftsekyflTMEPERQSDGTFCGTALLIVSvdsaTEQGVQFICQVRHPSL GEPLER------ >UniRef50_UPI00017B1183(491-588:1231) UPI00017B1183 related cluster n=1 Tax=Tetraodon nigroviridis RepID=UPI00017B1183 E=0.001 s/c=0.46 id=17% cov=71% ------------------------RATYFHPDVITFRWFCQGGELSPVasqaSSSPRPDSEGFFSAYSQCKLPKSELEKGSTKVWvsvhHIALKQPITRE ----- >UniRef50_P01837(5-104:106) Ig kappa chain C region n=41 Tax=Eutheria RepID=IGKC_MOUSE E=1e-10 s/c=0.68 id=18% cov=97% ---PTVSIFPPSSEQLtSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSwtdQDSKDSTYSMSSTLTLTKdeyERHNSYTCEATHKTSTSPIVKSF NRN- >UniRef50_C3YR07(150-240:546) Putative uncharacterized protein n=1 Tax=Branchiostoma floridae RepID=C3YR07_BRAFL E=8e-08 s/c=0.64 id=17% cov=91% --PPKVVVGPSKmyVVTRSKTVTLSCSVMDGYPNITSLMWKRGNVPIDTLRLNGPKYSGGNLETPSltIRYVDRMDAGIYACVVRHPASTKEL------- - >UniRef50_UPI0001792168(162-266:1220) PREDICTED: similar to sticks and stones CG33141-PA n=1 Tax=Acyrthosiphon pisum RepID=UPI0001792168 E=2e-05 s/c=0.48 id=16% cov=84% ------------EVQENHEVSIECVARNSKPASRIVWFRGDEEINPEQRSDNISEETadqtklKLFTVRSRIKVTAKSNDdrvKYKCEAHHQALSDPLST T----- >UniRef50_Q9JHJ8(169-254:322) ICOS ligand n=8 Tax=Murinae RepID=ICOSL_MOUSE E=8e-05 s/c=0.56 id=10% cov=87% -------ISTSDSSNPGQERTYTCMSKNGYPEPNLYWINTTDNSLIDtalQNNTVYLNKLGLYDVISTLRLPWTSRGDVLCCVENVALHQNIT------- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * A 1 822 * * * * 2859 * * * * * * * * * 1754 * * * * 1 0 * * * * * * 3463 0 0 R 2 * * * 1708 * * * * 2162 * * 3647 * 3587 1702 * * * * * 2 0 * * * * * * 5022 0 0 P 3 * * * * * * * * * * * * 40 * 5177 * * * * * 3 36 5329 * 1000 1000 * * 7298 1000 0 P 4 6081 * * * * * * * * * * * 207 * 4702 5428 5173 5077 * * 4 0 * * * * * * 8184 0 0 K 5 6449 * 6614 3104 * 6330 6334 * 2365 5911 3917 * * 3169 5258 2403 3172 3198 6160 * 5 0 * * * * * * 8217 0 0 V 6 6730 4984 * * * 5351 * 2863 * 2812 4676 * 4018 * * 5294 4442 1052 * * 6 0 * * * * * * 8271 0 0 Q 7 4708 * 6229 3083 4934 6551 3758 6248 3703 5424 6441 4740 6101 4723 4778 1891 2995 4917 * 4889 7 109 4067 6281 676 1418 * * 8284 2796 0 V 8 4858 * * 5802 6168 4461 * 1687 * 2768 4776 * 3848 * * * 6483 1673 * * 8 102 4550 5273 1849 469 0 * 8296 2208 1000 Y 9 * * 6090 4374 1917 3547 * 4221 5370 3313 * * * 5421 6328 2314 3760 5517 6232 4005 9 89 4985 5160 0 * 0 * 8386 2057 1763 S 10 3847 * * 3857 5445 6125 6664 * 5445 3411 * 5129 1614 3989 4848 3255 3120 5334 * * 10 41 6443 5928 0 * 0 * 8492 1000 1722 R 11 3403 * 5526 3908 * * 4764 5351 3952 4426 * 5427 2259 4053 2924 2881 4077 5289 * * 11 52 6720 5256 1000 1000 0 * 8490 1000 1000 H 12 3950 * 4076 2871 * 6245 4488 6468 3198 5016 * 4384 3196 4705 4036 2169 * 4275 * * 12 89 4386 6368 1201 823 * 0 8481 2409 1719 P 13 4486 5344 4355 3093 * 5408 6097 3690 * 4762 6548 6201 2344 4433 3476 3102 4049 3681 * * 13 44 5054 * 1567 594 1497 631 8563 2280 2292 A 14 2834 * 5389 5128 6240 4598 4821 4015 5032 2665 4988 4939 4935 6129 6444 3716 4418 2172 * * 14 34 6335 6554 0 * 963 1037 8575 1000 1719 E 15 4554 * 3459 2258 * 5033 4784 4709 3828 4468 5203 4820 4885 4470 5488 3522 3722 3534 6331 6451 15 77 4556 6735 1040 961 930 1073 8641 2484 1655 N 16 4315 * 4749 2512 5175 4906 4419 4398 5362 2654 * 4480 3057 5698 5542 4732 4043 5431 6414 4061 16 181 3607 4798 1056 946 1054 948 8668 3968 1699 G 17 * * 6264 3560 * 1117 6222 * 3741 * 6208 3189 6638 4163 4322 3285 * 6481 * * 17 42 5830 6449 673 1423 423 1975 8657 1586 2765 K 18 4945 * 2632 3017 6621 3535 4070 * 3097 6560 * 3719 6440 2743 4738 4711 4003 5354 * * 18 17 6456 * 1585 585 1000 1000 8675 1000 1735 P 19 4859 * 4472 2364 * 5750 5524 4941 3519 4365 6609 4698 3123 5618 4219 2802 3373 4644 * * 19 26 6977 6609 1000 1000 0 * 8698 1000 1000 N 20 2989 * * * * 4534 * 3699 6618 4721 4925 3488 5738 4864 5010 4223 4829 1409 * 4864 20 105 5491 4380 486 1807 0 * 8701 1688 1000 Y 21 * * * 3710 6451 * 4202 4517 4715 * 5608 5307 7049 4079 5013 4160 974 4115 * 6662 21 49 4894 * 721 1347 0 * 8654 2228 2854 L 22 * * * * 3456 * 6556 3314 * 671 5017 * * * * * * 3428 * 4454 22 0 * * * * * * 8696 0 0 N 23 4426 * * 4140 * 5562 * 3585 5444 3585 * 5623 6388 3935 4429 2949 1621 3710 * 6519 23 31 5544 * 2055 397 * * 8696 1669 0 C 24 4747 75 * * * * * * * * * * * * * * * 6200 * * 24 0 * * * * * * 8602 0 0 Y 25 6519 * 6754 4313 4768 6484 3466 5551 4660 2632 5529 5716 * 3618 4425 2481 3729 3584 4880 5139 25 0 * * * * * * 8607 0 0 V 26 1672 6754 * * * * * 2698 * 5073 * * * * * 2573 4122 1902 * * 26 13 * 6805 * * * * 8607 0 0 S 27 6538 * 6730 4323 5728 5047 5959 6760 4353 4795 5598 4284 6043 4067 3430 2148 2643 3967 4419 4855 27 0 * * * * * 0 8608 0 1000 G 28 * * 3580 4773 * 1202 4735 * 4332 6802 * 2950 5492 5673 3890 3775 6043 6535 * 6469 28 35 * 5402 * * 0 * 8608 0 1000 F 29 4639 6397 * * 1223 2915 * 4851 6494 4330 6276 5155 * * * 3609 * 4883 4669 3389 29 43 6888 5565 0 * 980 1020 8511 1000 1686 H 30 4153 6041 4649 * 2681 * 4174 * 3582 6645 5860 5429 5114 6687 4980 3017 6663 * * 1557 30 54 5913 5619 1000 1000 563 1629 8506 1081 2147 P 31 6708 * 4952 5913 * * 5394 * * 5756 * * 334 4906 * 4821 5790 5726 * * 31 30 6609 6560 0 * 0 * 8522 1000 2037 P 32 3028 * 3405 3149 5634 4995 6863 6731 2941 3906 * 4228 2467 3806 5779 4398 * 6125 6829 6761 32 55 6996 5091 1000 1000 0 * 8542 1000 1000 Q 33 3588 5762 3132 4172 6606 4318 5996 4420 5793 4431 * 3005 2456 4749 6622 3978 3625 4536 * * 33 68 6939 4713 0 * 0 * 8547 1000 2212 I 34 4033 * 6220 4577 * * * 1764 5417 2409 6712 5391 5392 5458 6629 6034 4016 2249 * * 34 67 * 4459 * * 0 * 8529 0 2823 E 35 6439 * 4494 2906 6725 * 4832 3901 3282 4480 4552 3717 6011 3131 4958 3231 3111 4706 * 6564 35 0 * * * * 666 1435 8571 0 3245 I 36 6788 * * * 3584 * 6492 1864 6392 2636 5080 * * * 6254 4998 3813 2032 4411 6347 36 0 * * * * 1000 1000 8545 0 1562 D 37 6375 * 5654 4635 6066 6855 5027 5717 3693 5621 5654 4672 * 3859 3284 3510 1975 5086 2943 5342 37 0 * * * * 0 * 8547 0 1000 L 38 * * * * 4658 * * 4634 * 3644 5570 5729 * 6749 5586 6512 5406 6631 485 6502 38 27 6822 6734 1000 1000 * * 8552 1000 0 L 39 * * 5764 4229 2836 * 6329 5604 2773 2148 * 5415 6511 4567 3375 4350 4835 5911 4614 3862 39 61 4589 * 519 1726 * 0 8553 2580 1000 K 40 5543 5208 5635 3865 * 3913 4872 5776 2255 4557 6113 3556 * 5114 1972 4942 6364 3964 * * 40 65 4498 * 2040 402 0 * 8553 3217 1000 N 41 6687 * 1714 4259 * 2980 6898 5827 4927 6588 * 1847 5496 5116 6293 4193 4944 * 6920 * 41 13 6812 * 0 * * * 8552 1000 0 G 42 6293 5641 3790 4314 5480 886 * * 4987 6265 * 3858 6588 5635 6439 3847 4745 5722 * * 42 45 5014 * 2757 231 * * 8552 2357 0 E 43 4963 * 5524 2829 * 4167 4615 5675 3141 4076 5319 4104 5550 3300 5072 3823 4573 2777 6439 6512 43 42 5124 * 2305 326 * * 8552 2369 0 K 44 4449 * 5800 2930 * 5827 5540 3376 3607 3506 * 4536 2528 4690 5001 3428 4319 3835 * * 44 0 * * * * * * 8552 0 0 M 45 4665 * 5078 * * * * 2571 4948 1586 4698 5523 4741 7065 5102 4355 4522 2636 * 6699 45 86 4118 * 1344 723 * * 8552 3420 0 N 46 6918 * 3139 3426 * 3995 5366 4888 4426 5075 * 4307 2764 4521 4019 3280 2616 6822 6591 * 46 39 6878 5807 2322 322 * * 8552 1000 0 A 47 2968 6425 5046 2957 6252 4119 4466 5195 5164 5055 * 5643 3712 4090 4168 3365 3527 3398 6513 * 47 80 4207 * 1032 969 924 1080 8541 3318 1672 E 48 4385 * 3722 3082 5345 3322 5248 5335 6274 5280 * 4174 4359 3272 3885 2452 4911 4249 * * 48 97 3940 * 2068 393 0 * 8547 3929 1000 Q 49 6284 * 4150 4023 6705 4629 5491 4636 6634 4595 5595 3643 4812 2788 5080 3493 2294 3633 * 5550 49 102 4731 5018 1535 610 * * 8552 2626 0 S 50 6618 * 4645 4536 6416 3631 5712 5324 4185 4127 5112 3867 3432 4983 3736 2759 2508 6657 * 5174 50 69 4414 * 1682 539 0 * 8512 3136 2432 D 51 4295 * 4192 3374 5041 4366 3574 6768 4193 4997 6674 4133 3988 3794 5072 3331 2806 4223 * 6341 51 31 5536 * 2114 379 * * 8552 1671 0 L 52 4760 * 5819 4582 4882 6582 4293 4830 3916 3626 6341 4669 2638 5111 5700 4216 2892 2839 * 4754 52 39 5237 * 1201 824 * * 8552 2137 0 S 53 4647 * * 3145 5395 5718 5728 4370 4530 3203 5295 5840 5175 3494 2762 4132 3537 3166 * 5392 53 0 * * * * * * 8552 0 0 F 54 5794 * 4550 4301 5648 4313 6801 3972 3371 3726 4657 4788 2604 3708 3460 4180 3838 5522 * 5729 54 25 5852 * 577 1601 * * 8552 1724 0 S 55 3928 * 3457 4200 6478 4070 3968 6768 4731 4473 5696 2134 4739 3820 5538 3969 3320 * * 5542 55 20 6194 * 2085 388 * * 8552 1674 0 K 56 3669 * 3825 3062 * 2909 5876 * 4033 5152 5622 4195 3658 4145 7002 2590 4640 4698 * 5128 56 37 5299 * 410 2016 * * 8552 2293 0 D 57 5690 * 993 3847 6503 3907 * 6631 4402 4979 * 2874 6971 6749 6283 4324 5289 * * * 57 41 6838 5691 2585 263 * * 8552 1000 0 W 58 4486 * 4948 6752 6443 913 5476 * 4264 6691 * 4330 5596 5285 5280 3412 * 5318 4825 6504 58 54 5297 6465 1883 456 0 * 8538 2411 1744 S 59 5603 * 5867 6698 4843 4849 5678 * 4889 2615 * 4840 * * 4748 3051 1265 5510 * 4804 59 68 5684 5223 1340 725 0 * 8541 2060 1000 F 60 * * * 4683 1475 6469 * 5229 6809 3634 6509 4906 * * 6324 4861 6744 6586 6419 1509 60 58 5067 6679 2121 377 1520 619 8532 2428 2311 Y 61 6813 4596 4584 5522 5250 * 5791 * 6359 6754 5503 3607 * 3176 4107 1428 2912 5469 * 5592 61 14 6682 * 1585 585 1571 592 8529 1000 2126 L 62 3208 4907 * * * 5673 * 2965 3861 3196 3883 * 6748 5622 6791 3351 3644 2234 6713 5249 62 29 * 5641 * * 0 * 8539 0 1725 L 63 5595 * 6424 5603 3662 * 4834 3628 6459 2857 6034 4954 6552 5195 4524 2644 2715 3831 4584 4336 63 31 6518 6614 0 * * 0 8529 1000 1669 V 64 4219 6417 4464 * * * 5530 5561 6363 5452 * 4402 * 6450 3969 896 3791 3660 * * 64 49 4899 * 1000 1000 * 0 8514 2342 2301 H 65 4941 * 4574 6680 4661 * 3747 2471 * 4190 * 6055 6890 4457 3929 3055 2457 4056 4986 4726 65 0 * * * * 619 1519 8514 0 2301 T 66 6736 4789 * 6634 6861 6602 * 3008 * 884 5411 * * 6778 4550 6487 4983 2920 * 6757 66 0 * * * * * 0 8536 0 1000 E 67 4054 * 3956 3078 * 5477 5522 5041 4568 4505 5597 3915 4139 3744 3481 5777 2278 4818 * 5137 67 13 6747 * 0 * 0 * 8536 1000 1000 F 68 4642 * * * 2836 * 5837 2712 * 2420 6451 * * * 6293 5067 4136 1639 * 5012 68 119 4396 4986 1202 823 * * 8552 2918 0 T 69 4314 * 3484 5378 * 5182 6950 5114 3527 4245 * 4539 3308 5769 4148 2744 2471 4256 * 4984 69 94 4204 6861 1780 497 1547 604 8520 3408 2160 P 70 3187 * 4990 3937 * 6714 6391 * 3896 3568 * * 2005 4215 3896 3907 3507 4618 4184 * 70 138 3451 * 1489 636 0 * 8515 4295 2212 N 71 3786 * 4942 2488 6284 3289 6469 * 3692 * 4809 3005 * 4111 5875 2467 3745 6417 6548 * 71 111 4316 5383 1470 646 * * 8552 3229 0 A 72 4469 5507 2369 3356 * * 3875 6189 4813 3822 5594 5136 3737 4280 3721 2858 5518 5613 5513 * 72 37 5289 * 1585 585 0 * 8575 2265 1805 V 73 3994 * 3702 2946 * 2174 5647 * 3694 4474 5515 3438 * 6625 3782 3375 5981 5073 5165 * 73 27 5774 * 1324 735 * * 8552 1730 0 D 74 4569 * 2077 3808 * 2228 5212 6723 4411 * 4675 4551 * 3606 4309 3717 5642 5091 * 6293 74 144 3395 * 1423 673 * * 8552 4523 0 Q 75 4247 * 4838 4046 * * 4268 4564 3494 5232 6512 3280 * 3630 4084 3874 2260 3283 * 6822 75 180 3095 * 1223 807 * * 8552 4834 0 Y 76 6439 * * * 2603 5289 4993 3376 * 3952 6576 * * * * * * 2873 * 1123 76 31 5563 * 1283 763 * * 8552 1758 0 S 77 5668 6818 6513 4548 6284 6723 * 3567 3621 5633 * 6480 * 4303 3637 2635 1563 4081 * 6780 77 0 * * * * * * 8552 0 0 C 78 * 74 * * * * * 6127 * 6600 * * * * * * 5289 * * * 78 0 * * * * * * 8552 0 0 R 79 6498 5561 * 2905 * * 5097 5031 3902 4412 4607 * * 3727 2152 3794 4454 2511 5267 * 79 0 * * * * * * 8595 0 0 V 80 2606 * * * * * * 3768 * * 6381 * * * * 6261 * 440 * * 80 0 * * * * * * 8571 0 0 K 81 4513 * 4904 2318 5565 6753 4318 5340 3740 6570 6715 4860 * 3387 3094 3190 3429 5274 4421 * 81 85 4128 * 1575 590 * * 8318 2489 0 H 82 * * * * 5570 5311 508 * * * * 2510 * 5064 5554 * * * * 5398 82 53 * 4786 * * * * 8253 0 0 V 83 4425 * 4841 1984 * * * 6251 3407 * * 6373 2103 3860 3796 3694 5219 4099 * 6601 83 0 * * * * 0 * 8119 0 1699 T 84 1623 6335 5270 6128 * 2511 5356 * * 6371 6132 * * * 6286 1925 3409 5256 * * 84 0 * * * * * * 8120 0 0 L 85 4965 * * * 5983 * * * * 544 5959 6166 * 5103 * 3288 5003 4575 * 4984 85 0 * * * * * * 7854 0 0 D 86 4173 * 3880 4156 * 3165 4700 * 3282 5126 * 5678 3145 2955 5772 2887 3207 5976 * * 86 0 * * * * * * 7874 0 0 K 87 3940 * 5286 2355 6059 5094 4272 * 3164 4788 * 5667 6182 2393 4569 3108 3506 * * * 87 20 6218 * 0 * * * 7888 1000 0 P 88 3409 * * 3556 * * 5633 * * 6234 * 3601 800 * * 3816 4070 * * * 88 45 6079 5979 0 * * * 7675 1000 0 K 89 5661 6032 * 4171 * * * 2192 3394 1590 5485 * * 5082 * 5538 4808 2889 5705 * 89 36 5349 * 0 * * 0 7667 1000 1000 I 90 5357 5615 5392 3292 * * 5448 3556 4519 4192 5653 5584 * 5788 2945 3339 1780 4494 * * 90 0 * * * * 0 * 7570 0 1000 V 91 5433 * 5562 3429 * 5314 * 5156 2235 4408 * * * 4009 2135 * 3373 2609 * * 91 0 * * * * * * 7144 0 0 K 92 4914 * 3680 2660 5204 * 4865 * 2814 * * 4850 * 5263 3636 3146 2030 5161 * * 92 64 4516 * 0 * * * 6983 1000 0 W 93 * * * * 2943 * * 4349 * 3476 * * * * * * * * 659 3356 93 80 4210 * 2322 322 * * 6219 1000 0 D 94 * * 2061 1363 * * * * 4418 * * 3153 * * * 4371 3227 4129 * * 94 0 * * * * * * 5582 0 0 R 95 * * * * * * * * * 4047 * * 1211 4020 2362 4148 3851 2993 * * 95 0 * * * * * * 5184 0 0 D 96 * * 953 3464 * * * * 3415 * * 2340 * 3300 * * * * * * 96 0 * * * * * * 4358 0 0 H 97 * * * * * * 572 * * * * 1612 * * * * * * * * 97 0 * * 0 * * * 2170 0 0 //