HHsearch 1.5 NAME c9qx1A_ FAM FILE c9qx1A_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9qx1A_.a3m DATE Sat Sep 6 11:56:58 2025 LENG 753 match states, 753 columns in multiple alignment FILT 29 out of 31 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 4.2 EVD 0.3182 -9.2946 SEQ >ss_pred CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHH HHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEE EEECCCCEEEEECCCCCEEEEEEHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH HHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC >ss_conf 9467876789999999989876066776766899999999999999999973236589998742699998885304103799999999886428763146 8999999875307789999999872268721789898999999862253106999999998621334552213789999999875204560256899999 9999999889852288872677886155686642014688643468611104454003432687777888874311000302335555445087342357 8613871346446887112111032102045467633441016111354556676323786887899832026998687778888642101688988999 8754158888999998788999999999877898689999999997048879999999984145313889999973024520899999999998787898 8765799999862268999872010012433778889862032676640351122312444688997618136899999999987404764334799999 9877544201112248899999998537521103354554789999999998888764101012678898899999999999713700457776520024 69999988887876666565545899999999999851166046898653129 >Consensus xkYxxxRDxxxxxxxxxxxxkxxxxxxxxxlxYdxlvxLvxxLxxxxeiAxxRpxnWqxfCxkxlpxLmxxxxxxxExvxxxxLxLLxxAixxsxxxxxx xxxlvxxlxxxxxxxllxxfixxfLlexnsxvRwqahxllxxxxxxsxxxxqexllxxlxxxlwpxlpxyGxkaaqfvdLlxyxxxkxxxxxxlxxxxxx xvxxLxxqnxxLxxhpnsxiYxxlxxxxvexdgxYLesxPClVCnnpexsIkxdsKfTtxsxtIxkixiridxkrtKmvrnrxvxaxxeLKNxwxkaxxx xLxxxqtexkxdfxlpixaxnxmiesxxxFyenlxasxexLxcprCsxxqxxxxvxxxxgxcxncxENxxqcxkcRxINYdxxdxxCxgCxxaxxxxclt llxxlxxxxxxxxxixxxdxllxelxnixxxxxxxxxxvxxLLxxlsexxxxatqxlxxLIxsxdixxxxllxxxlxxeDxcWexkLrxvxxLxxxxxxe xiilpcLxIlxxxxxppxpxsxxxxxxxxxxxxxxixxwLxxxxxwkxxxxpskxxxxxxyxWLxxllfsxxxsvRqxxcxLLxxLxxxsxxxxxxlxxl xxxlxxxxxxxxexxxExxxLxxxlixtexxxkxxlxxxgxlxxIxxllxkEixxxxxeExsLssDlsqGxxLkxLveLLxxflexxxixxxfxxxxkxx LlxxvLxsylxLRxLVVQRTkliddsxxxLxelLxxlsxxxxxxfmaxCixtl >c9qx1A_ NKYKIMRDKYKMQDLLQQLVKKYLDVSKEVGGHQQLTEIVDVLASITKLALIRPDMWRDVCSTHTTWLLRLACYTTDVVASQVVELLIVAVRDSSVGGQL SIQLADSIVEAENGEFIEKIIKRFLIGRDEQLRWTLHGMLRSVIQLASRQNQCILVKKLYNTIYPLAANLGVQGAQLVDLIATYAPRVFSSTELVAMTQS EISTIEKIRNTLNGDGYQGMYKLMSDLGLGWKSINFDRNPCLVCFTSAQHITCDAERGQCVQEITQLLIKMETTKTKLTGYRAACESLYLRNRPLPPYKL HVENNHTSEFFDANGTMNIEQLPFQSITMPMNNLAVAIRTLHSELCQQTQQLMYLHEELNRYDHASEVSVVFHKPQNISYYSTGQSCFGCLCNQLLHSVA LLHSSCDDENALNLILSSDSLIEKLGVLAQTYETLREEVEELLVRLMFDRLDVTTKVEKLIHTGDINLSVMVKSLMYAADPTWQQKLKLLIRLAMDKRDE NCCLQALMVLSKYLEATKSVTLDERKKIKLTPNKNITKWLTTDEEWKDCFAPTKSLPSNPYQWITDCLFSQWMSVRSAANQLLVNLSRQQFHEPVALLIL CENMSKLSDVPSSVCDQFMCSAHTIIDSSVNTKARLFVQQFHVYLIKRIHEECAKLHEQSVNLLSDNMFGERLRCFVELLSLLLSGSNVENVLLKAGADD LLIFLLHSTIFLKRIMTRRTRATDSSRIALEKLLKRVSCRDGTKLMSVCVESL >UniRef50_A8QBJ6(424-1508:2322) Putative uncharacterized protein n=1 Tax=Brugia malayi RepID=A8QBJ6_BRUMA E=0 s/c=0.61 id=29% cov=97% -KYRQVRDEHIIHDLLANLKKRL--KSRSSLEYFELSDIVSRINGIAAVSERRCVVWQRICLKELPWLMELACMMPDVACDAVLNLILLAIRTSEDSDDe lLCCSLVNILLSKQKPcALLKRLITRFLLGENEERRWTLHAILRATLQLASRPNQLLLINYLYKHTWPYAHEMGNRAAQLVDLLSYYLPRFLSKDELITV YKEAVATINSALYTLEKSRSSVIFEKLCEFIGSPDISVLSKSPCLICSDSDHpmeqlklsAIKLDSRFTTSAQMIklmghfevARIIIRLsEIKRTKMVK rfrfyycNKILESAIDLKNRPelwEKAADVKVNKGDTEidvqlpipvvtcnvvlemaEFYDTntagaadapefvhcprcstsvtpnpgicsNCGENVfqc vkcrainydEKEPFlcnscgfckyarleavlvgrslpsvqaieddndrkttyalmetllndiestrchigiiraflekcswdseptirpnmilkhmtvQS FTSFMSSLNLkedytlatlyrSAEKLHNKLCEQTRQLAAFRAEILRYDIENGDETLSDKPRTSNFHSNSDRCAGCMSALIVHCVSLIQATCSDTNAMEEI IREDFVFNRLvseptssNMIKVKYRKLmascldkhnvkyhavafwyhqevngctlgdavARSVHSLIWNLSEMSKEATQKMCELVENGALPCYLLTKSIF ENKFRFWEQKLRCLMRMAVigngstemdlhvlavflkicspcstnlkntfavdssgfsVDKVRNAGTFAVYLLPGYLLPTR----EEQSKTVLNASQNIG fednhkeseqeeveqnlvlddtvfhkimedmKMLDEEEpDFDKLLIPSERFPTigwlkgrfiwaeytrllqndsperersilqyirrctesdpkrkfSLY QWLTRCMFSSVAAVRAATCRLLVmlcfeinNNGEAQIGSPVDIALVLQKvllwMRKIRNVSADNIDEYFCLMRTLLTTrEINNVLVSKPVELHVDIVKRI LLASLDIRLHEVSRPSGDLsTGILLHHLIQVLNCMMQRDQNGWNLLHESSPVMLPLLLRTVCALKQVTVHRTFYVNESVKDLSMLLMRIALK-------- ----- >UniRef50_B3RV01(264-1300:2163) Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax adhaerens RepID=B3RV01_TRIAD E=1e-137 s/c=0.47 id=20% cov=96% -KYHIAKVQEICSSHGFRLSSTYIRPISISLPYDVVSQMVKHLRECLDISIARPASWHSFCFSNdiiVPYLIQVTVAFDEGIAPIILDLLAISYRENDNT NSSSITNAtSSLSESTNPSLTRKifeiipkttlahFLRKFLLESNvHNVRFQTLCLMLSIYESASMEDQKVVVDVLCD-LWPLIPAYGRKAKEFVGLLGH ISSKVLVAKKLNALSIKVIELLRVLNEKLKNHPNASIYNQLMSF-VDFEGYYLESYPCLVCNNPEipfnvvklTSLKADTRYTastqivklSCSHMISAV TIRIsDIKRAKMIRtiniyynTKTVQAIVELKNKRLwdKALSCQLNQNQSEMKVELPLPVVATNVMIE-FADFYDNFQASAETLQCPRCS-----ASVPA NPGICNHCGENVYQCHKCRAINYDERDPflcnSCGFCKYAKFDINVTArpccsVEPIKNDEDRKKVMSHIDTLLERADVIYKQLAAYRTPINALLAKVSE SNdtkdsneghtssstssssgsrvsktiqllsqkyasdckssfdelskiiqeilisrkeltdynskqslgelnvdstnsqillgsdessknvvsihsigk cygctvaavencvtvmkafatneimksllceediieelmknnlhsgttriHNTTRELLCLLAKDNKSISKQISYILERrvqqsmfshytkdnlaaslhqe mrllidtvdlEDSCWEDRLKTVIRLCLvasktncPVTIENVVVPCLRILSKLIQLPMSTSSNKKgkpghalvsiSTDGPEVYVNVKNWLIDDhgrvyENW KK-MSPSKlavslnstsrekfheTYLMSKYSrlwkfniqlrhgkaallssnqlllsesWLHDVLFSPSRSARQIICSILDSVCQDSYVCHRILDLLTQLL DYIDDAGEK-AMELLQTYKKL-TRPRHWKLYLVVKKLIPRIEILMEKEVQKlLLLEESSLSSDLTQGLSLKMLTEILIAIANQEQVK----VRCRSQLMR IVLNSYLSIRRLVIQRTKIIDETQDLLLEILEEL---------------- >UniRef50_Q54QG5(3652-4156:5875) Probable E3 ubiquitin-protein ligase DDB_G0283893 n=2 Tax=cellular organisms RepID=Y3893_DICDI E=4e-48 s/c=0.39 id=15% cov=24% --YYSIRDEFLLKKKFAGILDLEGktKGFSDEIGYDHLAKLISYLTLMLEVASDRPKSWQFFCAHNdvLPKLYKILFNLAEEpsslllelltyvfVDEIA EQPLSSTSQDTQQEssnnnnnnnsNDILMQDVDTKAKHISIFLQEQYfnvlIFNILLESNSSdLRSIASSFIYYLWRSSNNEQRIFINKSLWSKL-NNVA SYGKNASEFMDLLTYFL----------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------- >UniRef50_Q0IES4(3297-4370:5248) F14p3.9 protein (Auxin transport protein) (Fragment) n=3 Tax=Coelomata RepID=Q0IES4_AEDAE E=0 s/c=0.66 id=20% cov=98% -KYRQLRDLHSLDTHMKAVKDCCDGsappissigsSTSAILSYDALVELTEHFRACQEIASIRTGNWQKFCVRNsdiLPSLLNIScCQLEEGVSSIILQL LQSAICntqgvkqdsgsasatsmkisvlkerkdrdkseesdtatESKFDPAQCVALVTQIFNQVPFQNLTKFIRSFLLETNSTaIRWQAHSLVYAFYENS SEANKEMLLQCLWG-LWPLLPAYGKRTAQFVDLLGFLTLNTKSlSDKLPDYTAQAVSVLRQQNELLSKHPNAPIYTALGH-VLELEGFYLESEPCLVCNN PEvpysniklSTVKVDSKFTTTttivklvqSHTISKIILRIaDLKRAKMVRtiniyynNRTVQAVVELKNRpsmWHKARKVTLQSGQTDVKIDFSLPITA CNLMIE-YADFYETVSGSSESLQCPRCS-----AVVAANPGVCGNCGENVFQCHKCRAINYDEKDPflchscgfckyakfdysifgraccavdpiesaed rtktvqtihasldkadrsyktlqnnkqilellvqkvaehkldrtldetligsvvgssqvnkviqllaqkycveskstfeelskiiqkvqacrrelvaydr sqmdaasggpiaagspsdkavalnKCYGCALASTEQCLTLLRAMASNMPC-RVGLCNQGLVQElaLNNLRRGTNQIQDEVRQLLCLLTRDLPDATSDLCQ LLQdrvkmalSGTVPLANldsavrhemgLLEAMTAQDDSCWELKLRTVIELFLQASRDvrgpavAVIQPCLRIVQSLMCPPLPISKTNKDLTTQdlctvQ PTEGLTisyeKWITGDpqhsfAAWKARMPPitgtatpraedNATTPISSYRsvleqkrnryrkaylhekygkrwrqkvlnkgvnavpleltaaWLQPVLF NTNSRlGRQLACALVTSLSRTPERKREILDLLTSFLKNIGECGEASA-EFIALYRILAD-ETPWRQYLALKGVLSLIADLLTVEIEKIHrLEETTLSSDL AQGYALRQLVEMMAMFLDNPPIR----KAFKGKLLGSVLQGYLNLRKLVVQRTRLIDDAQEKLLEMLEEMTTGTEEEtaaFMAVCIDTV >UniRef50_D2V4H6(2234-3180:4029) Putative uncharacterized protein n=1 Tax=Naegleria gruberi RepID=D2V4H6_NAEGR E=1e-147 s/c=0.55 id=18% cov=97% --YNKLMDEKLFKSKLSDFVNGSDPVS--VWSPEKARRLVVKVNDIMDSVKARPENWINFCMEHenvLPALFEFSFLLDESVTIPLLLLNMSFVSDN--- -DSTLQKLSSLITTHSAKTLNKFVDFIFNGETNTIRAEAAHLMSKLVQFSVK-YKEMLFNIIVKRV-QSLPYYGKKGKEFLnNLLIPIYDHYPEKKQLIA --DELAKCLQSQNGLICNHPNSYIYDTIQQYIsVEPSGYYLETTPCLVCSDPEldfkelnlQDIIQGQKQSHSSHyyklsnsyTIESMSIDIsDFKRSKM IRtveiyfnnNQALDANDLPKNStvWQRAGTMNVAKGEQSATLTFSVPVTCCNLLVE-FSSFYFDL-ASMDALFCDSCG-----IAVYDKYGLCLSCGEN VFSCSNCRGINYDNLDaficSTCGTCKFATFAFSLSAKQVfigdkIRNEDDCKKSLQIIDNQLNSSEAKLSALKTKSSEIKSLLVKlktgdygeqklsev isslqdvynnetktlhgglshcqklmlttrkhlreyisanrqsdkkyyhestssqssnqfenkcygcannfvsnvmdffltvkdnndvnfndnlveelfk nisrgglkeksfklltcLSFGNEQVSEKVNSKlkeqivkycrktlkgydVTSQLVALTELLKRTFDEKDPFFNNRIQLLFEVLLETskfsssviICEEMI KPCLIILQKFISYGNSKPSSEHSTTDQTVVpmrglhfgyHQVKEGEMTFEMFKNNQIP-KKLPRNDFDILGREFLSNTLlnlssnTVRELTLQILQSLCL DNSHKQIGILQALTALLSEAMKRGEVSSCFFKLFNELVKQEER-KTLLSSKGFLSFVCKLLKKEvsyIHKLENSNTNQSQDLSTGSSLYFLVSLLSEFLI IPEILTEF--KTNEQHISTVLGSFLSLKSLVVQKTKATTDSYEMLKSLTEKLQdTEDDKKlFIAACVDTL >UniRef50_Q54QG5(4765-4956:5875) Probable E3 ubiquitin-protein ligase DDB_G0283893 n=2 Tax=cellular organisms RepID=Y3893_DICDI E=6e-32 s/c=0.74 id=21% cov=25% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -------------------------------------------------------------KWLEKLLFNSTSSIRLEIITLMGILSKNSNSRSLKFLDL LTKILPNATEAGEYSAEFFGLFNSFISTSQDRKIYLAVKGFIPFICDAIIKEIEHIKSKEGSFSTDVSQGFVLKTLVAILKSFLDVPTLKAKMK---KDN MLEKVLDAFLSLRGVIVQKNKLTEDSVRYLQELMKSLnneSVQDNKKFMAANIKAL >UniRef50_C5YJZ4(2759-3855:4828) Putative uncharacterized protein Sb07g010440 n=1 Tax=Sorghum bicolor RepID=C5YJZ4_SORBI E=1e-177 s/c=0.57 id=19% cov=98% --YYSVRDSWQYSHEVKKLNKIINKsgGFRNPVPYERSVKLIKCLSTLCDVAAARPKNWQKFCLKHmdlLPFLMDNFYHFSEECVIQTLKLLNLAFYSGK DanhnaqktenadlggstrttsqssdlkkkrkaddcsegsSEKSCVDMeqAVEMFSDKKGDMLKHFIDIFLLEWNSTgVRHEAKCVLFGVWYHAKNPLRE AMLSILLQKV-IHLPIYGQNIVEYTDLMTCLLGKVNDLSAKQndselvnkcltsEVISCIFDTLHSQNELLANHPNSRIYNTLSCL-VEFDGYYLESEPC VTCSCPDvpysrtklETLKSETKFTdnriiikcTGSFTIQSVTMNVyDARKSKSVKvlnlyynNRPVTDLSELKNNwtlWKRAKSCHLTFNQTELKVEFP IPITACNFMIE-LDSFYENLQASSlESLQCPRCSR-----SVTDKHGICSNCHENAYQCRQCRNINYENLDsflcnecgyskygrfefhfmakpsfsfdd mendddmrkglaaiesesenahrryqqlmgfkkpliklvssigeheidsqqkdavqqmmvslpgptckvnrkiallgvlygekckaafdsvsksvqtlqg qrrvlmtylhqksssdtnalpafsiprspNSCYGCSTTFVTQCLELLQVLSKHEYCRKQLVSA-GILSELfeNNIHQGPRTARTLARAVLSSFSESDEDA VQELNNLIQkkvmyclehhrSMDIAQSTREELLLLSEtcalvDEFWEARLRVTFQLLFSSikvgakhpaISEHIILPCLRIISQACTPPKSDGGDKESgl gvssltlhsknddttgNTSNNPSAKIQsdisgkihggsrrgqdipllsysEWENGASyldfvrrqykvsqavkgsvqkarhdsyksdylvlkyglRWKRr aCLESSKSDFSKfaLGYWVSDLILSScSQSIRSEICTLISLLCPSNTPRQFQLLNLLMSLLPRTLSAGDSAAEYFELLGTMIDSESS-RLFLTVRGCLTT LCSLITKEVSNVESQERSLSIDISQGFILHKLVELLNKFLEIPNIRGRFM---SDRLLSEVLEAFLVIRGLVVQKTKLINDCNRLLKDLLDSLlveSTEN KRQFIRACISGL >UniRef50_A2DQM4(274-1130:2034) Putative uncharacterized protein n=1 Tax=Trichomonas vaginalis RepID=A2DQM4_TRIVA E=1e-122 s/c=0.52 id=13% cov=90% -----------------------------SLSYSDSITLSKQLKGLNDISIIRPQNWVNYLHENSE-----------------LSTILCSIATSGYNQDF IVATVTLLrigEVKLTHDLILFLLQLLISSSLPVLRDESSKLLLLNYEEIISEIPKIL---------PEVSNCGSHSETFFSFLKELVPKL--GDKSADL IKSIQNSIVCETNSLKKLPNSFLYSQISQY-IDFPASYLDTRPCMICNNPEikatrymlSDIREFIKFSHDQLFVkfntplilQSIDLNFYAKKTTRlpr ivevyVSSQELNDPNELKSkKPQWSHVCDLEFERDSntAKVDFPLSLFATCIQFH-YTEFWE--EAEGQRLSCPLCHNGKPDP----RSGLCPNCHENIY QCRDCRYTNYEHLDgflcAECGSSPYCNFETHVTAIRSfshthISNENECDTSLSKADELLAEAHKYFSQLSNYKKDIDNVISptnnltvsektnklqdl ynekcrNLFNQLTQVVQHVCS-IRSAVGKYKNRITNSLSHADfnSCYNCRktyllnsLHFLGELttLPETILQQVEIPKLLIsfsddplfgstsiksLTN YCKininltnnilslfkqnLPNPSPalvnlvcslqeiddgyKQQRLETLVNCLNYCFEFLTSSPSFtslvfqpifesicKSPLIIRQKEKYLKYKILKEf sskinlkrnytlcldlfdeklmkvlLVECTNQSVRQIFSCLLKDTSEISHEIKLKIYENSLKILREFKYFSEQQIELYNLLQEILNTDKQIKYKAFHDGF FTTICHFLENEVDKTVKTEGELVLDLNVGIGIKQITNLILCF-TRNQVISRFIIIKKPEIAEKLIVSYFKLRSLIVQRSKHLDDSLNSLKEFAMLMMSKE ------------ >UniRef50_A2DC43(267-1128:1937) Putative uncharacterized protein n=1 Tax=Trichomonas vaginalis RepID=A2DC43_TRIVA E=1e-112 s/c=0.47 id=16% cov=89% ---------------------------KKPINYKIALELSQDLLEIEKIAQEHPEVWEDFLSEN-----------------TKLQNALEDILMSDYDDQF IVAVVSLLcLGHAKVKNIELVSKLFFTTGIQSVRKQMKDLLL---------IQPDVSASIIAKHFKDASNHGSQSEIFFSLVTELIKLISDPK---DLIN SLLVSLRTEYDLLKLHPNIYIYSELQKF-IDISSSYLDEQPCAVCNNPERlptlrnskDIVDGYKYTHEdvlmklkhpliissfilSYNIKKPekfpqTV KIFVCLEKILDNNQLLEIKE----WRFISEMKLNKNERASKLDLTLPVTATCVKFH----FCDIKEEQTHIIYCPACHSE-----VDQRTGRCPNCPENA FHCRKCREIDvVHPNRLICTSCGnSNFLEYSIQMNcvktfshTRINSDEDMEQSLEMIDNLMSKVHNTLNTLQEYKGKIEFLLsptneisvnqrtselkV IYNEKCKRSFQELTEFVQhvsaiRQSVSKYVGLTNSCNcecPENMCYNCKhmyitngLSVIGKFAeisttdVSDAMKFLISFCdveqfsssaissllsfc klnenltDKIIQLFLdSLPNPSPhlanllfqiLEIDDKFKLRRYKAVSNVLIETMKhvdknpalvsivvqpLSRALLKSNLLLRNRDDYLkfnilntlsn mklqtidifdnfsedliRSLLFSYNSQVRSDVSNLLFDISTISDKYfNKVFDFINQSFLNIQNLKKKENDQCLDLLSKLNEFSQKTHNHSINSKIIDNLI DKLLKETEQTYREENYLSMDLSVGYNIKLITNIIKPFITND-VDLLFICEKKSYLIEKLAKSYFILKSLILQRSKYLEDSSEIIKSaILKILSCK----- -------- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * N 1 * * 532 * * * * * * * * 1698 * * * * * * * * 1 0 * * * * * * 2199 0 0 K 2 * * * * * * * * 0 * * * * * * * * * * * 2 0 * * * * * * 2989 0 0 Y 3 * * * * 3990 * * * * * * * * * * * * * * 94 3 0 * * * * * * 3887 0 0 K 4 * * * * * * 3961 * 3275 * * 3539 * * 1057 * * * * 1911 4 0 * * * * * * 3887 0 0 I 5 * * * * * * * 2578 3539 * 3990 * * 1259 * 1911 * * * * 5 0 * * * * * * 3887 0 0 M 6 3961 * * * * * * 3243 * 1527 3275 * * * * * * 1658 * 3990 6 0 * * * * * * 3887 0 0 R 7 * * * * * * * * 3961 * 3539 * * * 235 * * * * * 7 0 * * * * * * 3887 0 0 D 8 * * 96 * * * * * * * * * * * * * * 3961 * * 8 0 * * * * * * 3887 0 0 K 9 * * * 2131 4815 3990 * * 3275 2149 4057 * * 3961 * 2183 * * * * 9 0 * * * * * * 3887 0 0 Y 10 * * * 3961 4457 * 1057 * 3539 * * * * * * * * * 2183 3275 10 0 * * * * * * 3887 0 0 K 11 2140 * * * * * * 2636 3275 2926 * * * 2183 * 3017 4899 * * * 11 0 * * * * * * 3887 0 0 M 12 * 3961 * * 2594 * * 3371 * 1219 3275 * * * * * * * * 2830 12 0 * * * * * * 3887 0 0 Q 13 * * 2953 3285 * * 3371 4336 2926 * * * * 3275 * 1537 * 4553 * * 13 0 * * * * * * 3887 0 0 D 14 3990 * 2322 * * * 2830 * 4457 * * * * * * 1259 2911 * * * 14 0 * * * * * * 3887 0 0 L 15 * * * 2183 * * 1366 * 2926 2322 * * * * * 4057 * * * * 15 0 * * * * * * 3887 0 0 L 16 * * * * 3205 3961 * 4336 * 1637 2322 * * * * * * 1964 * * 16 0 * * * * * * 3887 0 0 Q 17 2492 * * * 3961 * * * 1491 * * * * 2468 2882 3539 * * * * 17 0 * * * * * * 3887 0 0 Q 18 4044 * 2997 * * 3126 * * 2183 * * 2673 * 3275 3961 3441 * 3990 * * 18 0 * * * * * * 3887 0 0 L 19 * * * * 2430 * * 3080 * 1168 * * * * * 4815 * 2213 * * 19 0 * * * * * * 3887 0 0 V 20 * * * * * * 3377 * 1916 4457 * 4492 * 2473 4815 3961 * 2401 * 3651 20 0 * * * * * * 3887 0 0 K 21 4815 * 3675 * * * * * 1140 * * 3539 * 2651 3990 3961 * 4057 * * 21 39 5227 * 3000 193 * * 3887 1000 0 K 22 * 3349 * * * 3539 3651 2475 3275 3661 * * 5227 * 3371 5165 3008 3344 * * 22 0 * * * * * * 3887 0 0 Y 23 * 1627 * 4457 * * * 2183 * 2672 * * * * * 3539 * * * 2578 23 211 4674 3371 3170 170 * * 3887 1000 0 L 24 * * 2348 4764 * 4355 4684 3832 5029 3006 * 1638 * 5090 * 4836 5327 4534 * * 24 72 4355 * 1000 1000 * 0 3725 1000 1072 D 25 5327 * 3006 4764 * 3246 * 2887 1791 * * * 3405 * 3832 4534 3708 * * * 25 260 2601 * 2697 242 0 * 3725 1949 1072 V 26 * * * * * 1651 5227 * 3371 * * * 3961 * * 2303 4674 1987 * * 26 0 * * * * * * 3887 0 0 S 27 * * 4057 * 3474 2122 * 3961 * 4663 * * * * * 1289 3797 4815 * * 27 363 2874 3539 1000 1000 * * 3887 1381 0 K 28 4815 * * * 4298 4879 5234 * 2438 * * * 4673 2819 2077 2266 * * * 4549 28 0 * * * * * 0 3900 0 1000 E 29 4939 * 3157 3297 * * * 3255 2774 * * 1893 * 4815 * 2337 * * * * 29 0 * * * * 0 * 3900 0 1000 V 30 5062 * * 4633 * * * 4235 * * * * 1743 * * 2067 3185 2125 * * 30 374 2131 * 2681 245 * * 4235 1853 0 G 31 * * * * 5380 3484 * 2856 * 939 * * * * * * * 2676 3825 * 31 0 * * * * * * 4235 0 0 G 32 * * * 3266 * 2947 * * * * * 3519 1690 5062 * 1806 4231 * * * 32 28 5687 * 3170 170 * * 4235 1000 0 H 33 * * * * * * 3526 * * * * * 3889 * * * * * * 242 33 0 * * * * * * 4252 0 0 Q 34 * * 1289 1810 3583 * * * 3891 * * * * 3526 * 3880 * * * * 34 0 * * * * * * 4252 0 0 Q 35 3596 * 3880 3583 * * 4730 3891 3080 * * * * 3526 2199 2970 4016 4362 * * 35 0 * * * * * * 4252 0 0 L 36 2890 * * * * * * * * 914 * * * * * 1808 * 4362 * * 36 0 * * * * * * 4252 0 0 T 37 4730 * * * * * * 2654 * 3891 * * * * 3889 2921 3526 1153 * * 37 0 * * * * * * 4252 0 0 E 38 * * 2724 1652 * * * * 1969 * * * * 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