HHsearch 1.5 NAME c9liiD_ FAM FILE c9liiD_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9liiD_.a3m DATE Sat Nov 29 11:10:56 2025 LENG 273 match states, 273 columns in multiple alignment FILT 113 out of 227 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 4.3 EVD 0.4141 -1.0203 SEQ >ss_pred CCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCC CEEEEECCCCEEEECCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHCHHHHEECCHHHHHHHHHHHCC >ss_conf 9321022367888765857999932441012332058662466021573011027898886365789999998577667654432122321001123344 5444432211233333441001111220135554443344444455532347027782549991589886256899999999997188741790876259 7699960893799736999999998478972746316788888999998633301101011137778877439 >Consensus xxxxkxxxanxxGkxaxctLfivEGDSAxgsAxxgRdrxxqavlPLRGKiLNvxxasxxkixxNxEixxlixxlGlxxxxxyxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxlxxxxgxxxxxxxxxxxxxxxxxxxxxdxxxLRYgkIiImTDaDxDGxhixxlLLxxfxxxxPxLiexGxvxxxxt PlxkvxkgkxxxxfysxxExexxxxxxxxxxIkyyKGLGemxxxelxetxmnpxxxxvxxxexxxexfexlmG >c9liiD_ AKVHKHIKANLCGKDADTTLFLTEGDSAIGYLIDVRDKELHGGYPLRGKVLNSWGMSYADMLKNKELFDICAITGLVLGEKAFEEKEDGEWFTFELNGDT IIVNENDEVQINGKWITVGELRKNLMKFVKIDSSSVDMKKYKLQNNVRRSIKSSSMNYANVAIMTDADHDGLGSIYPSLLGFFSNWPELFEQGRIRFVKT PVIIAQVGKKQEWFYTVAEYESAKDALPKHSIRYIKGLGSLEKSEYREMIQNPVYDVVKLPENWKELFEMLMG >UniRef50_Q00942(415-654:1192) DNA topoisomerase 2 n=7 Tax=African swine fever virus RepID=TOP2_ASFB7 E=2e-06 s/c=0.23 id=29% cov=84% --VDKYTRArNAGGKRAqDCMLLAAEGDSALSLL--------------------RTGLTLGKSNPSGPSFDFCGMISL-----------GGVIMNACKKV TNITTDSGETIMVRNEQLTNNKVLQGIVQVLGLDFNC----HYKTQE------ERAKLRYGCIVACVDQDLDGCGKILGLLLAYFHlFWPQLIIHGFVKR LLTPLIrVYEKGKTMPVeFYYEQEFDAwakKQTSLVNHTVKYYKGLAAHDTHEVKSMFKhfdNMVYTFT-LDDSAKELFHIYFG >UniRef50_C6LX36(543-704:1492) DNA topoisomerase 2 n=3 Tax=Giardia intestinalis RepID=C6LX36_GIALA E=2e-11 s/c=0.45 id=34% cov=36% ---------------------------------------------------------------------------------------------------- -----------------------------------------------------NTLRYGHVMIMTDQDPDG-SHIKGLLINLFdTYWNGLARSNkFLDFF ITPIVRCTQARNMKTFYTIPEYKkwtQTVTDLPKWNINYYKGLGSSNTTDAKQYFQ---------------------- >UniRef50_B1BBK7(439-644:1417) DNA topoisomerase n=5 Tax=root RepID=B1BBK7_CLOBO E=6e-30 s/c=0.65 id=25% cov=72% -----------------TELYLAEGSSAQGSIVMGRNSKFQACYHVGGKMLSLLKADFEKIFKNKVVRELFQYLGCGIEIKSK----------------- -------------------------------------------HNKDLNTFDENNLNYSKIILATDQDTDAFQIRCLMLTAIYRLAPTLIKHGYVYIAES PLYEITTADKVYHAYTEEEKITILEELSKKGIKYdkperNKGLGEVDSDIIAETMMNPktrkiTRVTVQDVEKMANTFELWLG >UniRef50_Q7UUI4(31-237:243) DNA gyrase subunit B n=1 Tax=Rhodopirellula baltica RepID=Q7UUI4_RHOBA E=9e-10 s/c=0.32 id=26% cov=47% -----------------TELVIVEGDSAAKSVNQVRDTTRQSVLALQGKPMNVAKASRSVALRNEVLIRFASTL-------------------------- -----------------------------------LDHKLSASEDWIEALRKADRCRYARLVVLMDPDADGIHCGVLVLGFLLRFAPQLLQERRVCVVRP PMFL--------------------------------------------------------------------- >UniRef50_Q4RIW2(473-702:1568) DNA topoisomerase 2 (Fragment) n=1 Tax=Tetraodon nigroviridis RepID=Q4RIW2_TETNG E=1e-42 s/c=0.76 id=22% cov=75% ---------------SECTLILTEGDSAKSLAVSGlgvIGRDRYGVFPLRGKILNVREATHKQIMENAEINNIIKIVGLQYKKSYDDAESlrslrYGKIM IMTDQVSCRLGWFVGLGTSSASGLTPVCARTKMAPTSKGSSSTSSTTTGRRCSNTPSWRSSSHPSSRYRRLLPPQGT----------------ARRLRQP --VANLSTRCKQATKNKQEVAFYSIPEFEEWKkqtDNYKSWHIKYYKG------------------------------------ >UniRef50_A7ASL8(609-920:944) DNA gyrase subunit B, putative n=1 Tax=Babesia bovis RepID=A7ASL8_BABBO E=1e-55 s/c=0.70 id=21% cov=91% -------------------LFIVEGESAAGNAKQARNRRFQAVLPLKGKILNIEKISSDlKVMENEEIKLLISSIGLAVNPQTWRQDTLSHVENM----- -VPTSTRDALVATGPVGTTVDTTEASSSDSVDNNNVTATDNLGNIPVDASSLAQLPLRYGKIILLTDADVDGAHLRILLLGLLFRICPQLYEHGRVYIAC PPLYRITnmrKGNKARngpnasaytYAWSEEELpiainkemapynldsvpsediadteqtpEIKPDSMRGITVQRFKGLGEMMAQQLWDTTMNPDKRILR RISvqdgmRASKMLELLMG >UniRef50_Q196X4(427-652:1113) DNA topoisomerase 2 n=1 Tax=Invertebrate iridescent virus 3 RepID=TOP2_IIV3 E=1e-37 s/c=0.70 id=31% cov=64% -KVDGYDQANRLG--PDSVLIVCEGLSAKSYAVAGiqkglfnkKGRTYFGILPLRGKFLNVKNTTPLKIGQNKVVSDFIKVLNLKFNLDY---------- -------------------------------------------------------RKATNYATLNYGTLLILTDADKDGIHIKGLILNLIHELFPTLFhR QGFIYSMETPIVKILHKKGQPTlFYDENSFEDWRAQHPELKHfKYYKGLGTI-------------------------------- >UniRef50_C8XUB6(409-615:637) Topoisomerase II large subunit n=1 Tax=Shigella phage phiSboM-AG3 RepID=C8XUB6_9CAUD E=7e-36 s/c=0.74 id=30% cov=67% -EIEKYYPATARGDRSGCSLLLTEGDSASNPILNARDTKKIGLFPLRGKFINCLNAPRTKVMNNEEFKNLCTIHGGAVPGQPLDIS-------------- --------------------------------------------------------RYPQTVVATDADDDGIHIRGLLITLYCTYWPEYVRQGRLKLLRT PYMRVWCGKVMHEFMNNAEYEEFLktpDAKKITKKKYLKGLGGNSTEDFKRILNN--------------------- >UniRef50_O33367(410-793:815) DNA gyrase subunit B n=6 Tax=Bacteria RepID=GYRB_MYXXA E=2e-49 s/c=0.52 id=22% cov=93% -------------------LYIVEGDSAGGSAKQGRDRRNQAILPLRGKILNVEKL-LREMLTSAEIVTLITALGNGIGaEDYDPEKARYHRIFLMTDAD VDGSHIRTLLLTSSSGRCRSSCRRAISTSRSRRSYKVTRNKKDQYVKDEHALNEYLLKIAseHARVLTPGGELGGAELKALLEKVITYEERLEKQAKRRD ARvvdalvqgarlsaetltgrgcpggggegrlmtpssaacrtcwaacatswcrtpsttprswcsTPTrmepcgrrcsttpscrrrstwscrlcaehlrga gqgaVQGPRGRGEITVFSVQEVLAAvrKDAQRGLGLQRYKGLGEMNPEQLWDTTMNPATRTllqVRVEDAVesDEIFSLLMG # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * A 1 0 * * * * * * * * * * * * * * * * * * * 1 0 * * * * * * 1000 0 0 K 2 * * * 2049 * * * * 399 * * * * * * * * * * * 2 0 * * * * * * 1649 0 0 V 3 * * * * * * * 1232 * * * * * * * * * 800 * * 3 0 * * * * * * 2426 0 0 H 4 * * 1638 2132 * * 1983 * * * * 2339 * * * * * * * * 4 0 * * * * * * 2426 0 0 K 5 * * * * * 3192 * * 167 * * * * * * * * * * * 5 0 * * * * * * 2478 0 0 H 6 * * * * * * 1687 * * 1707 * * * * * * * * * 1384 6 0 * * * * * * 2599 0 0 I 7 * * 2579 2677 * * * 1774 * * * * * * * * 2486 3367 * 3203 7 0 * * * * * * 2599 0 0 K 8 3770 * 2394 3880 * * * * 1911 * * * 3528 3771 2043 * * * * * 8 0 * * * * * * 2820 0 0 A 9 270 * * * * 4524 * * * 5564 * 4953 * * * 3762 * * * * 9 161 3242 * 0 * * * 3320 1000 0 N 10 4684 * 4953 * * 3634 * * * * * 618 5157 5303 * 3304 4570 * * * 10 0 * * * * * * 3320 0 0 L 11 2799 5681 5881 * 4216 4788 * 5609 5798 863 4252 * * * 5174 * * * 4847 5230 11 0 * * * * * * 3358 0 0 C 12 1550 3083 * 5141 * 3261 * * * 3968 * * 1919 * 4665 5681 5609 * * * 12 0 * * * * * * 3358 0 0 G 13 * * * * * 61 * * * * * * * * * 5838 5389 * * * 13 358 2351 5387 1000 1000 * * 3498 1938 0 K 14 * * 4938 * * 5639 * * 512 * * * * 6088 2359 * 4775 * * * 14 91 4036 * 1000 1000 * 0 3572 1350 1000 D 15 4983 * 2952 5556 * 5209 * * 6217 2004 * 4861 5710 * 2777 1834 * 4375 * * 15 44 * 5053 * * 0 * 3572 0 1000 A 16 1064 * * 4532 * 5046 * * 6287 4207 4951 5092 5568 5826 * 1905 6171 * * * 16 117 3684 * 0 * 0 * 3911 1272 1000 D 17 * * 1354 1456 * 4443 * 5886 3531 * * 3817 6089 * * 6746 * * * * 17 133 3938 5460 2040 402 * * 4021 1881 0 T 18 4800 588 * * * * * * * * * 5040 * * 4422 5064 2381 * * * 18 61 4605 * 3000 193 * 0 4116 1575 1000 T 19 * * * 2140 * * * 4739 * * 3347 * * * * 3383 978 4892 * * 19 110 3764 * 3000 193 0 * 4175 1776 1000 L 20 * * * * * * * 3153 * 211 6155 * * * * * * 6693 * * 20 13 6804 * 3000 193 * * 4855 1000 0 F 21 * * * * 1256 * * 1634 * 3994 * * * * * * * 5113 6697 2663 21 0 * * * * * * 4855 0 0 L 22 4849 * * * 6835 * * 1190 * 1169 * * * * * * * 3767 * * 22 0 * * * * * * 4855 0 0 T 23 3323 4994 * * * * * * * * * * * * * * 1252 1156 * * 23 0 * * * * * * 4855 0 0 E 24 * * * 0 * * * * * * * * * * * * * * * * 24 0 * * * * * * 4855 0 0 G 25 * * * * * 0 * * * * * * * * * * * * * * 25 0 * * * * * * 4855 0 0 D 26 * * 313 3329 * * * * * 5274 * 5033 * 5528 * 5828 * * * * 26 0 * * * * * * 4855 0 0 S 27 * * * * * * * * * * * * * * * 0 * * * * 27 16 6487 * 2000 415 * * 4855 1000 0 A 28 0 * * * * * * * * * * * * * * * * * * * 28 0 * * * * * * 4855 0 0 I 29 3111 * * * * 1773 * 4076 1721 3270 5554 * * 5246 6908 4699 6825 5503 * * 29 0 * * * * * * 4855 0 0 G 30 3371 * * * * 809 * * 5167 * * 5444 * 6415 * 2607 3237 * * * 30 0 * * * * * * 4855 0 0 Y 31 6823 * * * 6121 5676 * * * 1705 * 4219 4521 6518 * 1265 3793 * * 4208 31 0 * * * * * * 4855 0 0 L 32 559 4956 * * 4716 * * 3639 * 3486 6825 * * * * * 5430 4337 * * 32 119 4484 4849 1585 585 * * 4855 1708 0 I 33 * * * * * * * 3423 1237 3682 5925 5113 * 6427 5143 6782 4268 1953 * * 33 54 4765 * 1585 585 * 0 4756 1523 1000 D 34 2519 * 4065 5247 * * * * 6263 4677 4307 4847 6861 1788 5919 2233 3995 6385 * * 34 15 6618 * 1585 585 * 0 4756 1000 1000 V 35 1870 5235 * * 5919 998 * 7001 * 6430 * * * * * 5399 6618 2951 * * 35 329 2292 * 1948 433 * 0 4756 2078 1000 R 36 * * * * * * * 3256 3865 6121 * * * * 590 * * 2756 * * 36 42 5895 6364 1910 446 * 0 4757 1305 1000 D 37 * * 1253 5717 6774 1828 * * * * * 2146 * * 6952 4773 * * * * 37 20 6218 * 1585 585 1195 828 4744 1000 1357 K 38 4556 * * 5133 * * * * 3691 * * 6228 4095 6763 646 3601 4900 6008 * * 38 0 * * * * * 0 4757 0 1000 E 39 5008 * 1986 2149 6373 * * * 3496 6699 6116 4655 6364 5267 2535 5322 4107 5371 * 6820 39 11 6978 * 1585 585 * 0 4757 1000 1000 L 40 7522 * * * 2332 * 4717 4020 3886 4120 * 3352 * 5754 2922 7325 2826 * 6559 2601 40 0 * * * * * 0 4757 0 1000 H 41 * 5555 * * 4039 * 4118 5304 * * * * * 815 6408 * * * * 1972 41 17 6408 * 2000 415 * 0 4757 1000 1000 G 42 960 * * * * 1120 * * * * * * * * * 5904 6803 * * * 42 0 * * * * * 0 4757 0 1000 G 43 3895 4721 * * * 4759 * 1610 * 3967 * * * * * 5922 * 1152 * * 43 0 * * * * * 0 4757 0 1000 Y 44 * * * * 1300 * * * * 1170 5009 * * * * * * * * 3077 44 0 * * * * * 0 4757 0 1000 P 45 4494 * * * * * 5768 * 6799 * * * 157 * * 4993 * * * * 45 0 * * * * * 0 4757 0 1000 L 46 * * * * 6052 * * 3983 * 198 * * * * * 6803 * 4602 * * 46 0 * * * * * 0 4757 0 1000 R 47 * * * * * 5768 * * 2136 * * * * 5904 457 6799 * * * * 47 0 * * * * * 0 4757 0 1000 G 48 * * * * * 22 * * * * * * * * 6052 * * * * * 48 0 * * * * * 0 4757 0 1000 K 49 * * * * * * * * 0 * * * * * * * * * * * 49 0 * * * * * 0 4757 0 1000 V 50 * 7343 * * 4523 * * 1199 * 2323 3993 * 2996 * * * * 2980 * * 50 0 * * * * * 0 4757 0 1000 L 51 * * 6364 * * * * 4265 7343 256 4486 * 6355 6820 * * 5618 7377 * * 51 0 * * * * * 0 4757 0 1000 N 52 * * * * * * * * * * * 27 * * * 5768 * * * * 52 67 * 4470 * * 0 * 4757 0 1000 S 53 4184 3953 * * * * * 3711 * 5825 6826 * * * 4678 4455 2988 819 * * 53 21 * 6100 * * * 0 4805 0 1682 W 54 4877 6047 * 1758 4553 6400 * * 5402 3681 * * * 5577 1841 7237 4112 * 3621 4230 54 40 * 5209 * * * 0 4787 0 1821 G 55 * * 2874 2795 * 2733 * * 1475 * * 3035 * 6619 3993 6114 * * * * 55 0 * * * * * 0 4714 0 2060 M 56 1163 * * 6916 6348 * 6754 2957 5115 2676 3959 5710 * 4652 * 5324 4939 5125 * * 56 133 4909 4198 0 * * 0 4714 1000 2060 S 57 4278 * 3562 6991 * 6880 * * 6256 * 7283 3040 4513 * 3555 1543 2095 * * * 57 45 * 5030 * * 1488 636 4529 0 2096 Y 58 3557 * 4114 7590 3841 * 4274 3890 5509 2022 5938 4481 4369 5309 4327 4217 7454 4022 * 3482 58 40 * 5178 * * 2402 303 4687 0 2085 A 59 2818 * 2298 4004 * 4414 5067 7273 2001 6798 * 4322 * 5380 3736 4687 4158 * * 7236 59 95 3971 * 0 * * 0 4647 1277 2434 D 60 6366 * 3717 3578 * * 6419 7230 1451 6647 5510 5504 * 2372 3087 5634 4812 5414 * * 60 0 * * * * * 0 4647 0 2434 M 61 3910 * * * * * * 1459 * 2967 2700 * * * * 4414 * 2053 * * 61 18 * 6364 * * * 0 4647 0 2434 L 62 3686 * * 7611 2919 4752 * 5331 5105 1493 2844 4382 * 7527 5572 4701 5715 5658 * 4392 62 0 * * * * * 0 4642 0 2465 K 63 3472 * 4701 2084 * 7213 * * 1717 * * 4086 4382 4508 5830 3726 3742 7385 * * 63 0 * * * * * 0 4642 0 2465 N 64 * 5980 6288 * * * * * 6320 * * 410 * 6412 * 2362 * * * * 64 23 * 5968 * * * 0 4642 0 2465 K 65 2120 * 3801 2140 * 4351 * 7168 2319 7161 * 5135 * 3733 * 4197 4331 * * * 65 0 * * * * * 0 4616 0 2623 E 66 * * * 265 * * * * * * * * 4351 5416 * * 5870 3670 * * 66 0 * * * * * 0 4616 0 2623 L 67 * 6014 * * 3576 * * 935 * 2323 6584 7389 * * * 4351 * 3154 * * 67 105 * 3839 * * * 0 4616 0 2623 F 68 3805 * 6246 5726 3000 7249 6019 5266 2649 6468 * 2956 * 2784 3642 4600 4519 3420 * 5626 68 0 * * * * * 0 4528 0 3015 D 69 2955 7063 2079 4491 * 7345 5973 * * 3239 * 2134 * 7610 5722 3295 3311 * * * 69 0 * * * * * 0 4528 0 3015 I 70 * * * * 3397 * * 1679 * 901 4332 * * * * * * 7063 * * 70 0 * * * * * 0 4528 0 3015 C 71 4657 2671 * 6246 4245 * * 1227 3687 3986 3766 6708 * 6167 7054 * 7106 4113 * * 71 0 * * * * * 0 4528 0 3015 A 72 2918 * * 7300 * 3752 5092 * 2287 5394 7054 4115 * 3293 4986 3150 2376 5324 * * 72 0 * * * * * 0 4528 0 3015 I 73 1546 * * * * * * 1381 * 6565 4136 * * * * 3619 5000 3744 * 5729 73 0 * * * * * 0 4528 0 3015 T 74 * * * * 5830 * 5798 2065 * 966 3579 * * * * * 4177 3748 * * 74 28 * 5722 * * * 0 4528 0 3015 G 75 * * 6537 * * 212 * * * * * 4175 * * * 3823 * * * * 75 15 * 6554 * * * 0 4487 0 3053 L 76 4572 3074 * * * 5411 * 3787 * 912 7033 3940 * * * * 3509 4283 * * 76 135 * 3481 * * * 0 4484 0 3061 V 77 3728 * 4458 3756 * 1446 6057 * 4105 * * 4604 6628 2859 6028 4151 4843 3848 * * 77 42 * 5132 * * * 0 4232 0 3430 L 78 * * 6649 5126 4325 * 4954 1985 6706 3071 5509 * 3942 4613 6970 5776 5902 2131 * 3339 78 142 * 3411 * * * 0 4219 0 3554 G 79 * * 4392 3958 * 1068 5216 * 3470 6323 6520 2596 5482 * 4716 * 5813 6500 * 5979 79 340 3708 2905 0 * * 0 4145 1000 3778 E 80 * * 3788 2143 * 4064 * 4451 2059 4401 5154 6548 3312 4729 * 5224 5613 4813 * 4370 80 164 * 3221 * * * 0 4066 0 3838 K 81 5807 * 2300 3292 * 6007 6247 * 1728 * * 5254 * 3392 * 3138 5839 3412 * * 81 181 * 3081 * * * 0 4051 0 3862 A 82 3452 * * * * * * * * 5295 * 3616 4911 * * 3929 2907 5715 * 862 82 112 * 3746 * * * 0 3988 0 3871 F 83 * * 1662 3849 3406 5849 * * 2394 3994 * * * 6023 5218 3837 5993 * 3036 * 83 345 * 2233 * * * 0 3951 0 3885 E 84 * * 2862 2466 * * * * * 4744 * 3036 3265 5264 2860 5211 2136 * * * 84 149 * 3350 * * * 0 3841 0 3980 E 85 2544 * 5012 1434 4982 * * 4233 * 3721 * * 4617 2146 * * * * * * 85 280 * 2501 * * * 0 3736 0 3976 K 86 * * 2217 1893 * * * * 1151 * * * * * * 3938 * * * * 86 445 * 1912 * * * 0 3552 0 4091 E 87 1767 * * 1744 * * * * * * * 3025 * * * 2851 2775 * * * 87 215 2851 * 2322 322 3939 97 3236 1000 4154 D 88 * * 2837 * * 3050 * * * 2419 * 3182 * * 1612 * * * * 3121 88 412 * 2008 * * * 0 3495 0 4067 G 89 * * * * * 977 * * * * * 2751 * * * 2641 * * * 2450 89 0 * * * * * 0 3199 0 4046 E 90 * * * 2423 * * 1542 2751 2524 * * * * * * * * 2758 * * 90 0 * * * * 3335 151 3199 0 4046 W 91 * * * * * * * 1872 * 3075 * * * * 2740 * * 1722 2686 * 91 0 * * * * * 0 3440 0 4171 F 92 * * * 1722 2686 * * 2740 * * 1872 * * * * 3075 * * * * 92 0 * * * * * 0 3440 0 4171 T 93 * * 3470 * 2740 * * 2714 * * * 1446 * * 3554 * 2686 * * * 93 0 * * * * * 0 3440 0 4171 F 94 3050 * * * 2686 * * * * 2059 1836 3075 * 3554 * * * * * * 94 197 * 2970 * * * 0 3440 0 4171 E 95 * 2874 * 2523 * * * * 2786 * 2550 * * 3361 * 3264 2536 * * * 95 0 * * * * * 0 3242 0 3964 L 96 * * 2536 * * * * * 1829 2523 * * * * 3361 * 2550 3264 * * 96 0 * * * * * 0 3242 0 3964 N 97 * * 2550 * * 2786 * * 2056 * * 1882 * 2536 * * * * * * 97 0 * * * * * 0 3242 0 3964 G 98 2550 * * * * 2523 * * 2005 3361 * * * * * * * 1695 * * 98 0 * * * * * 0 3242 0 3964 D 99 * * 1536 * * * * * * * * 2005 * * * 2536 2097 * * * 99 0 * * * * * 0 3242 0 3964 T 100 * 2536 * * * 3264 * * 3361 * * 2874 * * * 2786 2523 2550 * * 100 0 * * * * 3572 127 3242 0 3964 I 101 * * 2740 * * * * 1856 3075 * * 3470 * * 2714 * * 2233 * * 101 0 * * * * * 0 3440 0 4171 I 102 * * * * 3554 2059 * 2686 3075 2714 * * 2970 * * * 3050 * * * 102 0 * * * * 4467 67 3440 0 4171 V 103 * * 3724 * * 2905 * * 3246 * * * * * * 2279 1879 2270 * * 103 0 * * * * 4996 46 3573 0 4092 N 104 3804 * 3334 * * 4302 2988 * * * * 2377 * * 4005 1864 * * 3022 * 104 0 * * * * * 0 3639 0 4158 E 105 * * 3313 1639 3022 * * 2500 * * * * * * * 2550 3215 * * * 105 0 * * * * * 0 3639 0 4158 N 106 4005 * * 3804 * 3334 * * * 3313 * 2052 * 3870 2097 * * 3022 * * 106 0 * * * * 4771 54 3639 0 4158 D 107 * * 1801 2743 * 3054 * 4277 3383 * * * * 3926 * 4067 2554 * * * 107 0 * * * * 4648 59 3671 0 4094 E 108 3339 * * 2197 * * * * * 2111 * 3440 * 3171 4305 * 2802 4197 * * 108 0 * * * * * 0 3731 0 4181 V 109 * * * * 4426 3138 * 2759 * 2206 * * * 4305 2595 3440 4277 3112 * * 109 83 * 4162 * * * 0 3731 0 4181 Q 110 * * 4352 4007 * * * * * 3030 2761 * * 2092 3385 * 2429 3280 * * 110 0 * * * * * 0 3681 0 3984 I 111 2598 * * * 3385 * * 1830 3936 * * * * * 4227 3054 3030 3375 * * 111 88 * 4086 * * 4996 46 3681 0 3984 N 112 4001 * * 3431 * * * * * * * 1850 * * 2758 1651 3307 * * * 112 70 * 4401 * * * 0 3684 0 3976 G 113 2512 * * * * 2073 * * 4066 3052 * 2426 * * * 2180 * * * * 113 0 * * * * 3979 95 3594 0 4034 K 114 * * * 3434 * * * * 1663 4394 * * 3399 * * 1878 2496 * * * 114 0 * * * * * 0 3748 0 3981 W 115 * * * 4307 * 1930 * * 2306 * * * * 1860 * * * 3399 3124 * 115 130 * 3537 * * * 0 3748 0 3981 I 116 3204 * * * * 3182 * 2500 * 1657 3973 * * * 2995 * * 3346 * * 116 0 * * * * 4589 61 3607 0 3528 T 117 4293 3032 * * 4409 4325 * 2643 * * 4397 * * * * * 1075 4392 * * 117 0 * * * * * 0 3623 0 3540 V 118 4293 * 4397 * * * * * * * * 2075 3209 4392 3032 3206 3217 2554 * * 118 0 * * * * * 0 3623 0 3540 G 119 * 4293 * * * 2554 * * * * * 1398 * * * 2446 * 2213 * * 119 0 * * * * 4366 72 3623 0 3540 E 120 3670 3264 2884 1811 * * * * 3022 * * 3368 * 4073 * 3089 * * * * 120 64 * 4524 * * * 0 3783 0 3518 L 121 3231 3038 * 1701 * * * 4036 * 2628 * * * 4298 * * 3282 3508 * * 121 0 * * * * * 0 3756 0 3704 R 122 * * * * * * * 1431 * 2393 * * * * 1574 * 3282 * * * 122 0 * * * * 2803 223 3756 0 3704 K 123 * * * 2677 * * * * 2652 4761 * 3589 * 2160 3346 3971 2914 4440 * * 123 0 * * * * * 0 3982 0 3515 N 124 1930 5058 3220 * * 3812 * * 3573 * * 1754 * 5260 4666 * 3592 * * * 124 0 * * * 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