HHsearch 1.5 NAME c9l5wF_ FAM FILE c9l5wF_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9l5wF_.a3m DATE Sat Jan 3 18:50:12 2026 LENG 81 match states, 81 columns in multiple alignment FILT 106 out of 174 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 6.5 EVD 0.4683 1.6769 SEQ >ss_pred CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHCC >ss_conf 988999999997104899999999999520696675302789999999998889882528999999998391789997339 >Consensus isxfrxllxxIsxxLxxxdlxxlkflxxdxixxxxlexxxxxxxlfxxLexxxxixxxnlxxLxxlLxxixRxDLxxxixd >c9l5wF_ MDPFLVLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELLASLRRHDLLRRVDD >UniRef50_Q09HM6(20-96:700) Caspase-8 n=1 Tax=Molgula tectiformis RepID=Q09HM6_9ASCI E=9e-13 s/c=0.97 id=22% cov=91% ---YRQIMNTVMKNMRGENLKLSLYLCQDIIPQSI--DFKTCLQFVQHLEQSNKLSYINISLLVEILYRINRIDLLKK--- >UniRef50_UPI0001926F41(4-79:434) PREDICTED: similar to predicted protein, partial n=1 Tax=Hydra magnipapillata RepID=UPI0001926F41 E=1e-10 s/c=0.89 id=23% cov=95% ----KQKMFKIGAGLTHHNVIEIKYIFADKIGDGVLESINDGLEMIRVLERIGFIDKDNYKELIDLLESLGRKDLISIID- >UniRef50_UPI0000587370(119-202:447) PREDICTED: similar to caspase 8, partial n=1 Tax=Strongylocentrotus purpuratus RepID=UPI0000587370 E=1e-11 s/c=0.84 id=21% cov=101% LSAYRRLMLQISDSLSQDEKDHFTFYLSGgdsPLPVAAIEECKSLLQLFVLMEKKTLIGPEKLEYFTKFMQSIENLAIVKDIED >UniRef50_A7SWS8(5-85:524) Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SWS8_NEMVE E=1e-13 s/c=0.95 id=20% cov=101% VSKYRVFLLQLAQQLTDEDCRGMKFLAADFIPRAKRDTIEGVLEFFCELEDCKRMNADNLDILKFLLMQLKHFALVKKVEE >UniRef50_C3Z946(108-188:310) Putative uncharacterized protein n=1 Tax=Branchiostoma floridae RepID=C3Z946_BRAFL E=2e-12 s/c=0.90 id=24% cov=99% --PYRTLLYELGKEMKEDDMEIVKFMFKEDLGESILEKVRSPFDLLETLEDHGKIGpPNNVGKLEEAMKMAGRDDLVIKLKE >UniRef50_C3Y4H7(4-84:7154) Putative uncharacterized protein n=2 Tax=Branchiostoma floridae RepID=C3Y4H7_BRAFL E=5e-15 s/c=1.02 id=21% cov=100% -NPRQDLYLEISRNLLQEELRDLRNYVSGaKILPAGVVQNATAQEIFNQLEKEWNLKSGDLSLMADLLTKIGRNDYAEQAEE >UniRef50_Q98325(93-175:241) Viral CASP8 and FADD-like apoptosis regulator n=1 Tax=Molluscum contagiosum virus subtype 1 RepID=CFLA_MCV1 E=4e-07 s/c=0.67 id=24% cov=99% LTRYRKLMVCVGEELDSSELRALRLFACNLNPslSTALSESSRFVELVLALENVGLVSPSSVSVLADMLRTLRRLDLCQQL-- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * M 1 * * * * * * * 1758 * 2123 2144 * * * * * * 2009 * * 1 0 * * * * * * 5525 0 0 D 2 4690 * 2704 2994 * * * * * * * 3735 5920 5582 * 970 4076 * * * 2 0 * * * * * * 5912 0 0 P 3 4236 * 3691 5096 * * * * 3660 5207 * 4950 1139 4045 3273 4605 4556 * * * 3 21 * 6143 * * * * 6332 0 0 F 4 * * * * 1124 * 5755 * * * * * 6524 * 3821 * * 6478 6523 1255 4 0 * * * * * 0 6311 0 1000 L 5 6703 * 6322 * * 5260 * 6038 3141 5141 * 3575 * 3799 823 5449 5226 5358 * * 5 0 * * * * 0 * 6381 0 1000 V 6 4561 6203 5280 5078 6877 5890 5291 4146 2665 3441 * 5497 * 2340 4023 3660 4967 3120 * 5362 6 0 * * * * * * 6441 0 0 L 7 5714 5872 * * 3538 * * 3981 5712 816 3249 6825 * 4421 6902 * 5207 4995 * * 7 0 * * * * * * 6516 0 0 L 8 6352 6457 * * 4434 * * 5672 * 715 2483 * * 6841 * * * 5312 * 3501 8 0 * * * * * * 6544 0 0 H 9 3814 7182 6900 5411 3300 * 4542 4371 4922 1647 6346 3956 * 4225 5496 5662 4823 5345 * 3146 9 0 * * * * * * 6544 0 0 S 10 5105 6488 3454 2139 * 7038 5188 6839 2835 6274 6457 4376 * 3298 3333 3337 4205 * 6289 5788 10 0 * * * * * * 6544 0 0 V 11 * * * * * * * 882 * 1956 * * * * * * * 2325 * * 11 0 * * * * * * 6608 0 0 S 12 2697 5832 4193 6214 6636 2468 5921 * 6861 * 5336 3529 * 6679 6652 1423 5087 * * 6526 12 0 * * * * * * 6608 0 0 S 13 5698 6914 2774 1901 * 4438 * * 2619 5630 * 3302 * 3545 4360 3669 6055 * * * 13 0 * * * * * * 6608 0 0 S 14 5668 * 3251 2083 6263 3270 5310 * 3854 * 5274 2312 * 3833 5263 3254 * * * * 14 14 * 6731 * * * * 6638 0 0 L 15 * 6743 * * 6377 * * 3759 * 539 2853 * * * * * * 3673 * * 15 11 * 7069 * * * 0 6633 0 1000 S 16 5926 5816 3074 3811 * 3555 6441 * 4622 4715 6966 5089 * * 5155 2537 1755 3909 * * 16 0 * * * * 1000 1000 6636 0 1549 S 17 4675 * 2741 2465 6306 4367 5381 6669 3245 4964 6410 5079 5344 4214 4474 2947 4200 4890 6050 * 17 0 * * * * 0 * 6642 0 1000 S 18 6088 * 2526 1630 6731 5650 6808 * 3364 * * 5079 * 4121 3563 3421 3909 5539 * * 18 0 * * * * * * 6638 0 0 E 19 * * 1253 1388 * * 6399 * * * * 2748 * 5325 * * * * * 6287 19 0 * * * * * * 6638 0 0 L 20 * 5401 * 6811 3773 * * 3363 5343 1235 5264 * * * 6223 6380 4548 2048 * 6422 20 0 * * * * * * 6638 0 0 T 21 4323 * 3631 1965 * 7052 * 5711 2687 4973 6651 5587 * 4298 2560 3575 3957 * * * 21 20 6164 * 0 * * * 6638 1000 0 E 22 2670 6575 2962 3527 * 5654 5074 5650 3504 6329 5413 4416 * 4305 4865 2177 5134 5118 * 6197 22 0 * * * * * * 6638 0 0 L 23 6276 * * * 3430 * * 3097 * 871 2391 * * * * 6314 * 5190 * * 23 0 * * * * * * 6581 0 0 K 24 * 6162 * * 6150 6434 * 4088 663 5005 * * * * 2733 5061 5477 5403 * 6341 24 0 * * * * * * 6581 0 0 F 25 4688 * 6886 6679 703 6208 5904 * 5145 4549 * 4880 * * 4499 4631 6460 * * 3355 25 0 * * * * * * 6581 0 0 L 26 4661 5292 * 7007 5194 * 6679 3764 * 767 4366 6296 * 4894 6034 * * 5196 * 3448 26 0 * * * * * * 6581 0 0 C 27 4028 1399 * * 4074 * * 6265 * 2014 6063 6150 * * * 4220 6373 3454 * 4221 27 70 5059 5875 1392 692 * * 6581 2017 0 L 28 3182 6496 6150 5195 * 3876 6004 4855 2443 4358 5857 * 6784 3447 3154 2880 4413 4605 7054 5343 28 124 4789 4433 1000 1000 * 0 6578 1887 1617 G 29 4637 6517 1183 3727 * 2539 5694 * 3930 * * 3727 6294 * 4720 5427 * * * 5236 29 68 4446 * 623 1512 794 1240 6552 2380 3514 R 30 6507 4778 3556 4476 4867 * 2805 3994 2894 2761 7046 * 6249 6248 4553 6821 4004 4151 7072 3489 30 53 5428 6266 0 * 0 * 6550 1783 2169 V 31 * * * 6024 5625 * * 1162 * 1753 4299 6507 5364 6380 * * 5329 3353 * * 31 18 * 6332 * * * 0 6556 0 1000 G 32 6759 6667 5360 * * 2037 5820 * 5182 4746 * 5274 1303 * 5594 2902 4477 * * * 32 33 5477 * 1000 1000 963 1038 6547 1697 1640 K 33 2915 * 3951 4302 * 5728 5563 6874 2239 5736 * 5779 3899 3817 2498 3764 5529 4493 * * 33 36 * 5353 * * 0 * 6556 0 1000 R 34 2961 5755 6036 4252 * 1996 6047 6480 3877 6634 * 4502 6228 5945 2862 2684 3980 * * * 34 50 * 4878 * * 0 * 6598 0 1748 K 35 4290 6158 4347 3104 * 5246 4596 4624 1987 4659 * 4944 4862 5084 2808 4510 4876 4257 * * 35 50 * 4863 * * 1460 652 6587 0 2253 L 36 5008 7075 * * 5115 * * 3377 4213 1175 5226 6071 * 5255 3355 4320 4107 3923 * * 36 27 * 5769 * * 2157 366 6525 0 2868 E 37 6038 * 3987 849 * 5944 6405 5385 6283 5749 * 4593 4442 4383 5217 3629 5803 5493 * * 37 18 6305 * 1000 1000 520 1724 6532 1000 3048 R 38 7203 * 3198 2993 * 4843 5540 * 2406 5540 * 3562 6942 3999 2625 3329 4422 6072 * 6192 38 61 * 4597 * * 1000 1000 6577 0 1473 V 39 3732 4296 4614 5841 4417 * * 1777 4568 4139 4389 3956 * * * 4111 6543 2546 * 5264 39 104 * 3844 * * 727 1337 6541 0 3048 Q 40 3659 6829 3650 4240 * 6260 6596 * 2079 5071 6631 4854 6212 4722 3296 3121 2794 6307 * 5639 40 18 6353 * 1585 585 207 2902 6525 1000 3644 S 41 * * 2707 5232 * 5374 * * 4880 6034 * 3251 * 6921 4232 1709 1938 6207 * * 41 0 * * * * 0 * 6545 0 1000 G 42 2091 5542 * * 3304 2155 * 6891 * 3946 5865 6660 2337 6707 * 4800 7007 4451 * 5572 42 20 * 6211 * * * * 6583 0 0 L 43 * 6310 * 6190 4223 * 3545 3694 4955 1283 6374 6855 6551 3688 3731 5023 5170 4201 * 5900 43 17 6424 * 2000 415 0 * 6561 1000 1000 D 44 4487 * 1865 1636 * 5218 4822 * 4738 * 5453 * * 2790 6347 4198 5312 * * * 44 20 6153 * 1000 1000 * * 6583 1000 0 L 45 * * * * 3422 * * 2664 * 946 4194 * * * * * * 3344 4253 5369 45 0 * * * * * * 6583 0 0 F 46 5449 5665 * * 845 * * 3484 6153 2640 6539 * * * * * 6203 3624 6809 5479 46 0 * * * * * * 6583 0 0 S 47 5865 4568 4410 3269 * 6153 5542 4121 4836 3338 6987 4286 * 3194 3266 3334 3422 3508 * 6614 47 0 * * * * * * 6583 0 0 M 48 2943 4177 * 2460 4869 7169 3993 5059 3084 3557 4505 * * 3851 5311 * 4415 4608 6660 4062 48 11 * 6987 * * * * 6583 0 0 L 49 * * * * 5214 * * * * 249 2925 * * * * * * * * * 49 0 * * * * * 0 6585 0 1000 L 50 5963 5574 5886 658 * * 6735 4722 5140 4897 4241 7075 6142 3319 6201 6080 * * * * 50 0 * * * * * 0 6585 0 1000 E 51 3867 * 3882 2422 * 6142 4297 * 1916 * 6812 3809 * 3524 2868 5085 6220 * * * 51 0 * * * * * 0 6585 0 1000 Q 52 4836 5478 4675 2982 * 6556 4206 5044 3222 3157 4944 3833 * 3007 2712 6316 5339 4457 * * 52 0 * * * * * 0 6585 0 1000 N 53 5055 5970 2485 3288 * 1791 * * 5483 5552 5315 2172 * 5488 4745 * 6285 6762 6422 * 53 0 * * * * * 0 6585 0 1000 D 54 5448 * 7022 5276 4647 * 4576 3924 2068 1568 5312 6422 * 5418 4553 * * 4188 6535 4270 54 0 * * * * * 0 6585 0 1000 L 55 * 6043 * * 6033 * * 1372 * 1203 6326 * * * * * 6397 3335 5291 * 55 44 7318 5382 0 * * 0 6585 1000 1000 E 56 4569 5635 3662 4396 * 1871 5677 * 3544 6749 * 3995 * 6511 5673 1945 3830 * * * 56 88 4353 6627 2010 412 * 0 6595 2534 2205 P 57 4092 4904 4332 1853 * 6243 5985 5805 2987 5410 * * 2137 4921 6905 4594 5483 4983 * 5577 57 0 * * * * 277 2515 6635 0 2614 G 58 6263 * 1590 2992 * 2428 * 6316 4964 * * 3173 * 6158 5001 3900 3955 * * 6481 58 0 * * * * 0 * 6585 0 1000 H 59 * 6243 1746 * * * 7032 6082 3457 * * 997 * 6088 4749 5493 * * * * 59 0 * * * * * * 6583 0 0 T 60 7180 5472 6399 6875 4384 6923 * 5534 * 1040 * 5483 5324 * 5305 * 3586 2788 * 3548 60 0 * * * * * * 6583 0 0 E 61 3767 6903 2548 3220 4899 3635 * * 4356 4708 * 5313 * 4499 4008 2359 3494 7169 * 5915 61 0 * * * * * * 6583 0 0 L 62 4695 5822 6460 4869 2213 * 6621 4056 3999 2081 5865 6814 6211 5232 5523 4871 6325 3723 * 3278 62 0 * * * * * * 6583 0 0 L 63 * * * * 3707 * * 4393 * 305 5505 * * * * * * 4495 * * 63 0 * * * * * * 6583 0 0 R 64 2861 * * 2578 * 4660 6559 4179 2428 4432 5103 * 6875 4916 4197 4805 3539 3273 * 7157 64 0 * * * * * * 6583 0 0 E 65 7489 6381 2389 1806 6328 7081 4215 5117 3094 6518 * 5198 * 4522 4848 3598 4836 5054 6644 6395 65 0 * * * * * * 6577 0 0 L 66 4524 5135 6885 * 4807 6440 * 2224 6304 994 5277 * * * 5822 7489 * 3578 6518 * 66 0 * * * * * * 6577 0 0 L 67 * 4816 * * 3490 * * 6520 * 328 3880 * * * * * * * * * 67 11 7079 * 1585 585 * * 6577 1000 0 A 68 4679 6361 5048 2763 5312 5574 5539 5670 2946 6611 6289 5183 6069 3074 3077 4841 4289 4824 * 2942 68 0 * * * * * * 6566 0 0 S 69 3311 6685 3955 4329 * 5426 4209 4114 3344 4683 6913 4512 6943 3749 4052 2860 3047 7214 6350 5052 69 10 * 7211 * * * * 6566 0 0 L 70 5056 5388 * 6910 5778 * * 892 6424 2337 6182 * * 5463 * 5574 5800 3384 * * 70 12 * 6931 * * * 0 6595 0 1000 R 71 * 5354 5561 4660 * 1616 3952 * 2762 * 6333 2485 6972 4788 4208 4028 5885 6788 * * 71 75 * 4298 * * 0 * 6577 0 1696 R 72 6183 5367 * 6554 * * 4652 * 4359 6290 * 6104 * 4587 333 * * * * * 72 0 * * * * 0 * 6542 0 2373 H 73 4277 6553 4422 3917 5439 * 3543 2994 3676 3646 6497 3043 3569 4563 4527 5747 4158 5005 * 5359 73 0 * * * * * * 6570 0 0 D 74 4905 6250 396 4849 * * * * 4725 * * 5227 * 6591 4573 5085 * 6344 * * 74 0 * * * * * * 6570 0 0 L 75 * * * * 6364 * * 4886 * 145 * * * * * * * 5255 * 5408 75 0 * * * * * * 6546 0 0 L 76 2453 6204 * 5526 * 5869 * 3548 4485 1939 6426 6060 * 6140 5079 4877 6366 2025 6400 * 76 0 * * * * * * 6560 0 0 R 77 6676 * 6884 2957 * * 6821 5898 1673 6813 * 3200 5766 3842 2935 3240 4049 * * 6532 77 0 * * * * * * 6576 0 0 R 78 6094 * 4016 3160 5270 * 5342 3585 2141 3248 4785 4473 * 4056 3490 5113 6305 5319 * 4359 78 0 * * * * * * 6498 0 0 V 79 4457 * * * 6375 * * 1613 * 2259 4866 * * * * * * 1426 * * 79 0 * * * * * * 6484 0 0 D 80 5748 * 2833 1561 * * 5573 * 4136 * 5812 3351 * 2201 5739 4711 6034 5734 * * 80 0 * * * * * * 6254 0 0 D 81 * * 1135 1893 * * * * * * * 1860 * * * * * * * * 81 0 * * 0 * * * 5709 0 0 //