HHsearch 1.5 NAME c9jmnC_ FAM FILE c9jmnC_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9jmnC_.a3m DATE Sat Jun 21 12:42:43 2025 LENG 1110 match states, 1110 columns in multiple alignment FILT 20 out of 22 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 3.2 EVD 0.3181 -9.5935 SEQ >ss_pred CCCEECCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEECCCCEEEEEECCCCCCCCCEEE ECCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEEEEEEEEEECCCCC CCCCEEEEEEECCCCEEEEEEEECCCCCCCCEEEEEEEEEEEEEEEEEEEECCCCHHHHCCCHHEEEEECCCEEEEEEEECCCEEEEEEECCCCHHHHCE EEEEEECCCCCEEECCCEEEEEEEEEEECCCCCCCCHHHHHCCCCCCCCCCEEEEEECCCCCHHHEEEEEEECCCCCCCCCHHHHHCCCCCCEEEEEEEE ECCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCE EEEECCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCEEEECCEEEEEECCEEEEEEEEECCCCEEECCEEEEECCCCEEEEEECCCCEEEEECC CCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCEEECCCCCEEEEE CCCEEEEEEEEEEEEECCCEEEEECCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCH HHHHHHHCEEEECCHHCCCCEEEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HHHHHCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCEEEEEEEEEEEECCCCEEEECCCCEEEEECCCEEEEEECCCCCCCCCCCCCEEEECCCEEEEC CCCCCCCCCC >ss_conf 9010016441023465442232342148753613310022343114333556505786401101562003456632010482899980345211352342 0355542100168970332343235642110563156662754212247887411211252110003577314689830221111211223454113414 4665001137637852899985216840352120246662111245676401126011000101013420320477886067516767534741020111 1243101688740034125411269995467777860232126776654200024302443565311100201135777686664011243112012453 0443211245640132002544667765225788763367654332346765332001156862001014557777655442000111100341037712 6751254225655640789999752010024788876235515653311568862068899998110106524348982268667798058858999606 8663479971675303687512102432223567752023322676653366533346743133454305673011344412676210000575127883 5630688887789865352599613144088279999999998998999999988667767888988732110014444455677644100146777630 4553320113423102111112356454324762676788799899999998775443334379999988614022338999988999999999999999 9998999999999999998558999999999751113468789999999987665301346556678999999999999999999999999999989976 1211025446876899980249981899999764787599998545762387116763684589805984999521211540266311576217437731 4756588789 >Consensus xxxxxxqpxyxxxxxxxxxxxsxxxgxxyxxxxxyxnxtlxltgxxpxxxxxxxxxxxtxxxxxxxxfxsxxxxxxxpfxdgxxxxxxxxxnxxxxxvxx sxxxxxxxxxpxxxigxxxgxxxxxxxxxxxxxtxxxxxxxxgtxixxxxxxlxxxxxxxxxxxxxxxxxxxxxxxnxxxxxxxxxxxxxcxxxxxxxxx xxxxxxxxxxxqxxxxxyxyxxxxxgxxxxxxfxfxxlxxgxxlxxxxxxpxsxxxxxxxxxxxxxVxxLxxxxxLvxfdxxGxixxavDCxxxxxxxLx CxxxsFxxxtGvYxxsxfxxqpxgxxxxxxxxxxcxxxvxxxxxxpxxxxwkRxvfxNCxxnxtxlxxxxxxxsxxcxxvxpxxlxxxcxxsvxxDxfxi xxsxxxxlxxgxxgxxxxfnykxxxaxtxcxxxxtixxxxtxxxxxxxnxxyxxxxxcfxxxgxxxxxxxxxxxxxxcxxxxxxxxxxxxxxxxxxnxxx xxxgxxxxxxxxxxgxixxxxvixxdxxxgxxxvxxxxxxxsxixtdxCxxYnIYGxtGxGvixxxnxxxxxxgxxxxxxsgxllxfxxxtgxxyxVxPC xxxxxxxvxxxxxxxxxxlxxxxxxxxxxxxxxxnxxxtxxgcxxxxxxxxxtxxnCxxpigxsxcxxxxxxxxxxxxxxxxxxxxxvxxxxxxxxnixI PtnFtlsvtxEyiQtxxxkvsIDCxxYVCngnxrCxxLLxQYgsfCxxIexaLxxxxxlxdxxxxxlxxxxxxxxxxxxxsxfxgdyNxsxlxxxxxxRS aIEDLLFdKVxLGtvxdYkxCLxCAQyYNGImVLPgVvdaexmAmYTaSLtggmxxTaAaaIPFaxavQaRlNylalttxVLxeNQkiiAnsFNxAigxI qxgFxtvsxALxKIQdVVNxqxxALxxLxxQLsnNFgAISsSIxdIyxRLDxleAdaQVDRLItGRLtaLnafVtQxLxxxxevrxsrxLAxqKINECVK SQSxRyGFCGNGtHixSlxqxAPnGixFxHxxlvPtxxvxVxaxxGlCvxxxxxxixxkxgxxixxxnxxwxiTxrxxyxPxpitxxnxxxxsxxvxxxn xtxxxxpplx >c9jmnC_ CIVVDMQPSYFQRDWPRPINMSAADGIIYPVGRTYANITIMLSGLFPHQADKGKQYIYSMYHMVNDPFISNYSYYTEPFDNGFVVRIGANSNITGSSVVG SANATVKKIYPALMLGSVVGKFPSNKTGRYFNHTLVILPEKCGTQITALYCVLQPKNQTNCTGHTTYTSYVLVENKNLKQSLQTWFDLKDCLFEKKYNVS ADEREEWFGITQDQQGVHLYTSRKNGFKSNNMFLFATLPIYERLRYYTVMPRSIKTNDHMAWSAFYIYQLHKLNYLVEFDVEGYIVRASDCGANDYTQLQ CSYGQFDMNSGVYSASYFNAQPRGYYYVANELEECALDVLFKNIAPQIANYSRRVFTNCNYNLTKLLSLVEVDEFVCDKTTPESLATGCYSSLVVDWFAL PLSMKSTLAIGSAEAISMFNYNQDYSNPTCRIHATINSNVSSSLNFTANNNYAYISRCQGTDGKPILLQKGQLPNIACRSGVLGLSNDVDYFGYNFNGRI FYIGRKSYTPRTSEGSIQMVYVITANYAEGPNNVCPLKTDNLDSLLGQCIDYDINGVVGQGVFQKCNSTGIPSQVFVYDSFHNIIGYHSKNGTYYCMAPC VSVPVSVIYDKSSNSHATLYGSVACDHIKMIPSVGLLQTAVGCVIGFHNTSDTVEDCNLPLGQSLCAKPPSNNTFGLAVMKYENPLKVEVLNSSEFEISV PTNFSFRVTEEFIETSIQKVTVDCKQYVCNGFERCEQLLEQYGQFCAKINQALHGVNLRQDDATKSLFESIRVPQSAPLMASLSGDYNLSLFETPGNYRS ALEDLLFDKVTLGYMKGYDECLICAQYVAGYKVLPPLYDSNMEAMYTASLTGSIAGALAASLPFAQSIYYRMNGIGITQNVLMENQKLIANKFNQALGAM QTGFTTTNQAFQKVQDAVNANAQALSKLASELSNTFGAISASIGDILKRLDTLEQEVQIDRLINGRLTSLNAFVSQQLVRSEAAARSSQLVKDKVNECVK SQSSRNGFCGQGTHIVSFAVNAPNGFYFVHVGYHPTDYVNQTSAYGLCDSSNTKCIAAKNGYFIKNGSDDWMFTGSSYYQPEPITNFNSRSVEPEVTFQN LTNNLPPPLS >UniRef50_P59594(24-1123:1255) Spike protein S2 n=151 Tax=Betacoronavirus RepID=SPIKE_CVHSA E=1e-152 s/c=0.49 id=31% cov=94% ----DVQaPNYTQHT-------SSMRGVYYP-DEIFRSDTLYLTQdlFLPFYSN------VTGFHTINHTF----GNPVIPFKDGIYFAATEKSNVVRGW VFGSTMNNKSQ--SVIIINNSTNVVIRACNFELCDNPFFAVSKPMGTQTHTMI--------FDNAFNCTFEYISDAFSLDVSEKSGNFKHLREFVFKNKD GF--------LYVYKGYQPIDVVRDLPSGF--NTLKPIFKLPLGINITNFRAILTAFSPAQDiwgTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQN PLAELKCSVKSFEIDKGIYQTSNFRVVPSGdVVRFPNITNLCPFgEVFNATKFPSVYAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFSN VYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFMGCVLaWNTRNIDATSTGNY--NYKYRYLRHGKLRPFERDISNVPFSPDG--KPCTPP---ALNC Y-WPLNDYGFYTTTGIGYQP------YRVVVLSFELLNAPATVCGPKL-STDLIKNQCVNFNFNGLTGTGVLTPSSKRFQPFQQFGRDVSDFTDSVRDpK TSEILDISPCSFGGVSVITpgTNASSEVAVLYQDVNCTdvstaiHADQLTPAwriystgnNVFQTQAGCLIGAEHV-DTSYECDIPIGAGICASYHTvsl lRSTSQKSIVAYT--MSLGADSSIAYSnntIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQYGSFCTQLNRALSGIAAEQDRNTREV FAQVKQMYKTPTLKYFGG-FNFSQIlpdPLKPTKRSFIEDLLFNKVTLadaGFMKQYGEClgdinardLICAQKFNGLTVLPPLLTDDMIAAYTAALvsg TATAGWTFGAGaalqIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPA ICHEG--KAYFPREGVFVFNGT-SWFITQRNFFSPQIITTDNTFvSGNCDVVIGIINNTVYDPL- >UniRef50_B3FHU5(206-1058:1226) Spike n=17 Tax=Coronavirinae RepID=B3FHU5_CVTKE E=3e-95 s/c=0.41 id=32% cov=67% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -----------------------------------------------------------------------------------------------INKLR CAYQQFNFSTGFYDIDTFVPVTSNITYLPyPDLKDntgqevCDFYVALKG-------------DHVIYNQSCVDSKYPFFKLKCNNTY----------SW DNDKLCI---------LGSEIYVPGYNV---YTNTQHSYAGTIPNYPTCSSKGLSLENI------YNNIGFNRFC-------VTKLLTTRDISSITQYTC VYV---VSVEGFDSY----NQGIVYSYVGVNFDFGTAMYSVktAPMQF----IYTEQCHKYNIYNIRGVGQILNVTGkdnTTLVDGGLVITSGSGLLAFR N-NGSLFSVQPCRTVSTQAVI--VNGSFVGLFVPASCWLADQFNLGNHTEYVDGGCLISNKTISRKRRSTNAVYTGECtglfaAMGTSCIYSNGTVLNRT LPQPsvqtsVQPLLGVVANVSIPKELTLAVTTEYLQTRYQKVTIDCAKYVCGDSTRCRTLLQQYGSFCQSVNAILSGVNENEDNGllqyAEAINTGYTLN FTGYNVSNLGGfdlslvlPKNLTLAQNQG--RSTIEDLLFDKvVTLGVSevdQNYDKCiasrggsftnladLTCAQFYNGVMVLPGVVDPGLMAVYTGSL IGGMALggiTAAASIPFATQIQARVNYLALTQSVLLDNQNLIANSFNKALKGIQSaldtvsqgfvevarGFESVTVALNKVQDVVNTHSDILNKLMAQLS VNFGAVSSSLNEIYLKLDQINADAQVDRLITGRLTALSTYVASLQLAAYKADQSRRLALQKVEECVKSQSMRYGFCGNGSHVLTIPQSAPNGIFFIHYTY QPTSYVTIEAVPGLCVTTPSGkyGVMPKTGSgIIFRQNDTFFVTSTQLYEPKLLSysevvnltscEANYYNVsESETPFQPALPNF----- >UniRef50_A8JP00(42-996:1128) Spike glycoprotein n=3 Tax=Rhinolophus bat coronavirus HKU2 RepID=A8JP00_9ALPC E=5e-95 s/c=0.37 id=30% cov=80% ---------------------------------------------------------------------------------------------------- -------------------GAYPSTNKAKWFCPTNVGRPVGTGVGIGVYAQTAQASYETGGSGAGGYTFSVSPKHvTNLTWSLWVHRpwgananvTVRLC RWWQKFSFNETAHFQPAGpssafeclvngsFPSSQHKGYMFGVTWYNDFVRIIFPPTVFELQVDGLQWEYVQFTGPVNAGRMTKFNVVTEISSV--LVLT DQSGAVTRYSYCADGFVNGLQCKLRLFDIPPGVYSNSEVEY-PVALYTVVHNMSVCPQRP-ESYCGSNYCPFKRVVFSNCVVNYTSwtsgLLRDYQHLVL PNGKFNP---FTECNG----------LNRIVD---------------------DCVTGFVLRVGRGTAVNRTVITPYLKPNECFG--------------- ------------------WSWNDYQDSI-YDWWIAD---------FVSTGAFVCEKNPDAP--------RTGVCITYTIEKVTFQGVLYESNFTFAQYYN VLY--FGSQLKYVRILGKVYEVAPCFEASYDVLF-RSSSSFGLLYRSFDCNQLrisasrfaeRLLPSHNGTATALGCLFNATYAPnDTMVNCTNPLGDGF CADLLSNVV--VRRMTFEKHDTtyVAPVTIERF-TELPLDHQLVLTEQFLQTTMPKFSISCETYICDVSKACKNLLFRYGGFCQKIEADIRGAGVLLDSD VSGLYSTIAAKTSSIMPT--TDRFNVSQFFLPKvqstserfESRSVIEDLLFSKIETtgpGFYGDYYNCkknaiqdLTCAQYHNGILVIPPVMDAETLGM YggiaAASLTLGIFGGQAGITTWSLAMAGRLNALGVVQNALVDDVNKLANGFNQLTASVSKLALTTSSALQAIQAVVNQNAAQVESLVSGITENFGAIST NFKVISQRLDKLEADVQMDRLINGRMNVLQLFVTNYKLKIAELRNTHRYVQSLINECVYAQSLRNGFCGQGLHVLSLMQNAPSGIMFFHYSLIPNNTIIV KTTPGLCESDElgSKCIVAKDGVLVSANLSYWQWSPRNLYKPENLTFANVIAVSRGANYTTLNRTFDIP-- >UniRef50_B2BW33(468-1268:1472) Spike protein n=1 Tax=Beluga Whale coronavirus SW1 RepID=B2BW33_9GAMC E=5e-95 s/c=0.44 id=31% cov=67% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------------------------------------------------AMPQTFISTLNYTTALVTFD-KGNVRSVIDCNSEKpFDRL RCDLQTDVVSDGFYPVNIKTNEAKentTFIDVPATLANLTLEVFVSSPEQSPA---------CVIKSYKCVDtryfYISDYSYSCaENGIPNDAAGAAYC RGVLD------------QINNYGVRGMdFKGKCPFAGS------------------KVNSGLTFDKICFGV------YEQGCQSDKACRFGF-------- ---YFDNVQFSQYGNKLYYKPQDLG--------FIDYQFGTLFKNSLVQSNIIQ--EGCHDYDIYGYKGTGVVKPFSDySYLQTGGLIMLDSGGFPSLFR YNFALYEVTQCTREVAQLAVASNNAIGYYLPKQVTIDGVNASTSCNTTGAFKYCYyddvihVGRDVSNVTINVCNpsLMMENSHCINIQGNFMVNEPAIT FNSTQYQPLLGVSG-DVQLPRTLMLHTTTEFIQTHSPKIVIDCTKYVCGSSERCRRILVKYGGFCESIMRLLNGVNMADDVSVTDFLDnfnsfdniSVSL QNLNASFGQFEG-YGFQKFlpksfdfdgSDPRDARSTIEDILFDKVTtvgLGTVDAdYDKCtkglsvadLVCAQYYNGIMVLPGVADAEKMAMYTGALVG GMVLggiTSAAAIPFATQIQARVNYLALTQNAIQENQKIIVQQFNKAIDSMtsafqsvNEGFSAVSSAITEVQNAVNAQSQALTKLLGQLNYNFGATTSS IKELYERLAKLEADVQVDRLINGRLTALSAFVAARQVEAAKVASQRVLAAEKINECVKSTSNRYGFCGNGAHIISFPQNAPNGMLFVHFSLVPNETITVK GIIGLCLNNSIGIVPAKDrGMFIQCSNGTY--------------------------------------- >UniRef50_Q65984(386-1300:1453) Spike glycoprotein n=344 Tax=Alphacoronavirus RepID=SPIKE_CVCAK E=3e-89 s/c=0.36 id=31% cov=75% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------SFYSYGEISFGVTDGPRYCFA-LYNGTALKYLGTLPPSVKEIAISKWGHFYIN-----------------------GYNFFSTFP IDCISFNLTTG----------DSGAFWTIAYTSYTDALVQVENTA-----IKKVTYCNSHINNIKCSQLTANLQNGFYPVASSEVGLVNKSVVLLPSFYS HTSVNITIDLG----MKRSGYGQPIASTLSNITLPMQDNNTDVYCIRSNRfSVYFHSTCksslwddvFNSDCTDVLYATAVIKTGTCPFSFDKLNNylTF NKFCLSLNpvGANCKFDVAART-RTNEQVVRSLYVIYeeGDNIVGVPSDNSGLHDLSVLHLDSCTDYNIYGITGVGIIRQTNSTLL-SGLYYTSLSGDLL GFKNvSDGVIYSVTPCDVSAHAAVIDGAIVGAMTSINSelLGLTHWTTTPNFYYYSIY-----NYTNertRGTAIDsndvDCEPIITYSNIGVCKNGALV FINVTHSDG--DVQPISTG--NVTIPTNFTISVQVEYIQVYTTPVSIDCSRYVCNGNPRCNKLLTQYVSACQTIEQALAmgarlenmEIDSMLFVSENAL kLASVEAFNSTETLDPIYKEWPniggswlgglkdiLPSHNSKRKYRSAIEDLLFDKVVtsgLGTVdEDYKRCtggydiadLVCAQYYNGIMVLPGVANDD KMAMYTASLAGGITlgslGGGAVSIPFAIAVQARLNYVALQTDVLNKNQQILANAFNQAIGNITQAFGKVNDAihqtsqglatvakvLAKVQDVVNTQGQ ALSHLTLQLQNNFQAISSSISDIYNRLDELSADAQVDRLITGRLTALNAFVSQTLTRQAEVRASRQLAKDKVNECVRSQSQRFGFCGNGTHLFSLANAAP NGMIFFHTVLLPTAYETVTAWSGICASDGDRtfGLVVKDVQLTLfrNLDDKFYLTPRTMYQPIVATSSDFVQIEGcDVLFVNAT-------- >UniRef50_Q8BB25(41-1228:1349) Spike protein S2 n=85 Tax=Betacoronavirus RepID=SPIKE_CVP67 E=0 s/c=0.90 id=35% cov=94% ------------------VDVTNGLGTFYVLDRVYLNTTLLLNGYYPisgatfrNMALKGTRLLSTLWF--KPPFLS-------PFNDGIFAKV-KNSRF SKDGVIYSE-------FPAITIGST-----------FVNTSYSIVVEPHTSLING---NLQGLLQISVCQYTMCEYPHTICHPNLgNQRIELWHydtDVV SCLYRRNFTYDVNADYLYFHFYQEGGTFYAYFT-DTGFVTKFLF---KLYLGTVLSHYYVMPLTCNSALSL---EYWVTPLTTRQFLLAFDQDGVLYHAV DCASDFMSEIMCKTSSITPPTGVYELNGYTVQPVAtVYRRIPDLPNCDIEAWLnSKTVSSPLNWERKIFSNCNFNMGRLMSFIQADSFGCNNIDASRLYG MCFGSITIDKFAIPNSRKVDLQVGKSGYLQSFNYKIDTAVSSCQLYYSLPaanVSVTHYNPSSWNRRYGFNNQSFGSRGLHDAVYSQQCfntPNTYCpcr tsqciggagtgtcpvgttvRKCFAAVTKATKCTCWCQPDPSTYKGVNAWTCPQSKVSIQpgqhcpglglveddcsgnpctckpQAFIgwssetclqngrc nIFANFIlndvnSGTTCSTDLQQGNTIITTDVCVNYDLYGITGQGILIEVNATYYNSwQNLLYDSSGNLYGFRDYLSNrTFLIRSCYSGRVSAVFHANSS EPALMFRNLKCSHVfnntilRQIQLVNYFDSYLGCVVNaYNNTASAVSTCDLTVGSGYCVDYvtalrsRRSFTTGYRFTNFE-PFAANLVNdsiepvGGL YEIQIPSEFTIGNLEEFIQTRSPKVTIDCATFVCGDYAACRQQLAEYGSFCENINAILTEVNELLDttqlQVANSLMNGVTLSTKIKDGINFNvDDINFS PVLgclgsecNRASTRSAIEDLLFDKVKLsdvGFVQAYNNCtggaeirdLICVQSYNGIKVLPPLLSENQISGYTLAATAASlfpPWTAAAGVPFYLNVQ YRINGLGVTMDVLSQNQKLIASAFNNALDAIQEGFDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISASLQEILSRLDALEAKAQIDRLINGRLTA LNAYVSQQLSDSTLVKFSAAQAIEKVNECVKSQSSRINFCGNGNHIISLVQNAPYGLYFIHFSYVPTKYVTAKVSPGLCIAGDI-GISPKSGYFI-NVNN SWMFTGSSYYYPEPITQNNVvvmstcavnYTKAPDLMLNTSTPNLP---- >UniRef50_A3EXG6(192-1139:1274) Spike protein S2 n=4 Tax=Rousettus bat coronavirus HKU9 RepID=SPIKE_BCHK9 E=0 s/c=0.86 id=34% cov=70% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------------------------------------------------------VAHLINRDLLVSYFNNGSVANAADCADSAAEELY CVTGSFDPPTGVYPLSRYRAQVAGFVRVTQRGSYCTPPYSVLQDPPQPVVWRRYMLYDCVFDFTVVVDSLPTHQLQCYGVSPRRLASMCYGSVTLDVMRI NETHLNNL------------------------FNRVPDTFSLYNYALPDNFYGCLHAFYLNSTAPYAVANRFPIKPGGRQSNSAFIDTVINAAHYSPFSY ----------------VYGLAVITLKPAAGSKLVCPV-ANDTVVITDRCVQYNLYGYTGTGVLSKNTSLVIPDGKVFTASSTGTIIGVSINSTTYSIMPC VTVPVSVGYHPNF-ERALLFNGLSCSQrsraVTEPVSVlwsasataqDAFDTPSGCVVNVELRNTTIVNtCAMPIGNSLCfingsiATANADSLPRLQLV NYDPLYdnsTATPMTPV-YWVKVPTNFTLSATEEYIQTTAPKITIDCARYLCGDSSRCLNVLLHYGTFCNDINKALSRVSTILDSALLSLVKELSINTRD EVTTfSFDGDYNFTgLMGCLGpncgatTYRSAFSDLLYDKVRItdpGFMQSYQKCidsqwggsirdLLCTQTYNGIAVLPPIVSPAMQALYTSLLVGAVA SsgytfgiTSAGVIPFATQLQFRLNGIGVTTQVLVENQKLIASSFNNALVNIQKGFTETSIALSKMQDVINQHAAQLHTLVVQLGNSFGAISSSINEIFS RLEGLAANAEVDRLINGRMMVLNTYVTQLLIQASEAKAQNALAAQKISECVKAQSLRNDFCGNGTHVLSIPQLAPNGVLFIHYAYTPTEYAFVQTSAGLC HNGT--GYAPRQGMFVLpNNTNMWHFTTMQFYNPVNISASNTQ-------------------- >UniRef50_B6VDX8(223-1046:1192) Spike glycoprotein n=1 Tax=Thrush coronavirus HKU12-600 RepID=B6VDX8_9GAMC E=0 s/c=0.85 id=30% cov=68% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------CDKDLYDHLR CQQSSFSLTDGFYSTAKYTTnqQRKTIFVTLPK-----------------------------HTYTETISILPNISNPAYP------------------- -----DGSTNGPALGWWVGTMNVLFNNSQTLCVNSSFFMVNIT-FKCWLKPHPTKPSDEYKCIGGLPTAQVKLPDWPFAPYYSFSQLCLSSTYQVGYSTF YFQYWNQGTNKRWESKPLFYYTYQTGTQYTYVTKPVISF-TDVSELSLYECVDYNIYGVIGSGIIQPSNISYLN-GLYYTSSAGQLLAFKNsTTFQIYTV QPCDSPGQVIVYNNSFIGAITASNQTILN----------FKSRIATPTFYYHTNATSVqgNCNTaPLQFSSIGICPDGSIMQVNTTVDTLPATTIITSG- --NITIPLNFTISIQAEYLQIQAQHTVVDCQTYVCNGNAKCLQLLQQYSTACSNIEQSLTMSARLDNAETLAMVQTSTQGYHLSKIEQHDNQYNLTaILP NKQGGRSAIEDLLFDKVVtngLGTVdQDYKECtkgvsladLACAQYYSGIMVLPGVVDAEKMAMYTASLTGGMFFgglTAASSIPFSVAVQARLNYVALQ TDVLQKNQQILANSFNQAMGNITLAFSSVNDalqqtseviqtvanALNKIQDVVNKQGSALNHLTLQLQNNFDAISHSIADIYARLDEVEANQQVDRLIT GRLAALNAYVTQVLTQISQLKAQRQLAQEKINECVKSQSDRFGFCGNGSHLFSITQAAPNGILFLHTVLTPTDRVQVNAIAGICVSDSAFVLREPNLAFF QH-DGKWLISPRRLFQPRPATvADFVQIQSCEVTFYNTTYDELPQL- >UniRef50_P05135(208-1018:1163) Spike protein S2 n=1237 Tax=Avian coronavirus RepID=SPIKE_IBV6 E=0 s/c=0.81 id=31% cov=53% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------CYAYSYNGPS LCKGvyRGELTKSFECGLLVFVTKTDGSRIQTRNEPFTLTQHNyNNITLDRCVEYNIYGRVGQGFITNVTNYAINYNYLadggmaILDTSGAIDIFVVQG EyglNYYKVNPCEDVNQQFVVSGGKLVGILTSRNETGSQPLENQF--YIKIINGTRRSRRSITGNVTNCPYVTYGKFCIKPDGSIST---IVPKELEHFV APLLNVTENVLIPDSFNLTVTDEYIQTRMDKVQINCLQYVCGNSLECRKLFQQYGPVCDNILSVVNSVGQKEDMELLYFYSSTKPSgFNTPVLSNVStGE FNISLLLTPPssaSGRSFIEDLLFtsvESVGLPTDDAYKKCtagplgflkdLACAREYNGLLVLPPIITAEMQTLYTSSLVASMAFggiTSAGAIPFATQ LQARINHLGITQSLLFKNQEKIAASFNKAIGHMQEGFRSTSLALQQIQDVVNKQSSILTETMASLNKNFGAISSVLQDIYQQLDSIQADAQVDRIITGRL SSLSVLASAKQAEYYRVSQQRELATQKINECVKSQSIRYSFCGNGRHVLTIPQNAPNGIVFIHFTYTPESFVNVTAIVGFCVnpaNASQYAIVPANGRGI FiQVNGSYYITARDMYMPRDIT------------------------- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * C 1 * 0 * * * * * * * * * * * * * * * * * * 1 0 * * * * * * 1319 0 0 I 2 * * * * * * * 987 * 1013 * * * * * * * * * * 2 0 * * * * * * 1319 0 0 V 3 * * 1013 * * * * * * * * * * * * * * 987 * * 3 0 * * * * * * 1319 0 0 V 4 * * * * * * * * * * * * * * * 1013 * 987 * * 4 0 * * * * * * 1319 0 0 D 5 * * 545 * * * * * * * * * * 1668 * * * * * * 5 0 * * * * * * 1802 0 0 M 6 * * * * * * * * * * 1624 * * * * * * 566 * * 6 0 * * * * * * 1802 0 0 Q 7 * * * * * * * * * * * * * 0 * * * * * * 7 646 1470 * 0 * * * 1802 1000 0 P 8 * * * * * * * * * * * * 0 * * * * * * * 8 0 * * * * * * 1802 0 0 S 9 * * 1668 * * * * * * * * 1470 * * * 1624 * * * * 9 0 * * * * * * 1802 0 0 Y 10 * * * * * * * * * * * * * * * * * * * 0 10 0 * * * * * * 1802 0 0 F 11 * * * * 646 * * * * * * * * * * * 1470 * * * 11 0 * * * * * * 1802 0 0 Q 12 * * * 1668 * * * * * * * * * 545 * * * * * * 12 0 * * * * * * 1802 0 0 R 13 * * * * * * 1470 * * * * * * * 1624 1668 * * * * 13 545 1668 * 1585 585 * * 1802 1000 0 D 14 * * 1624 * * * * * * * * * * * * * 566 * * * 14 646 * 1470 * * * * 1802 0 0 W 15 * * * * * * * * * * * * * * * * * * 0 * 15 0 * * * * * 0 1319 0 1000 P 16 * * * * * * * * * * * * 0 * * * * * * * 16 0 * * * * * 0 1319 0 1000 R 17 * * * * * * * * * * 1013 * * * 987 * * * * * 17 0 * * * * * 0 1319 0 1000 P 18 * * * * * * * * * * * * 0 * * * * * * * 18 0 * * * * * 0 1319 0 1000 I 19 * * * * * * * 953 * * * * * * * * * 1048 * * 19 0 * * * * * 0 1974 0 1000 N 20 * * 426 * * * * * * * * 1967 * * * * * * * * 20 0 * * * * * 0 1974 0 1000 M 21 * * * * * * * * * * 1967 * * * * * 1940 1048 * * 21 0 * * * * 0 * 1974 0 1000 S 22 * * * * * * * * * * * * * * * 303 2400 * * * 22 0 * * * * * * 2335 0 0 A 23 2352 * * * * * * * 1386 * * 2400 * * * 2108 * * * * 23 0 * * * * * * 2335 0 0 A 24 1350 * * * * 1413 * * * * 2108 * * * * * * * * * 24 0 * * * * * * 2335 0 0 D 25 * * 2352 2347 * * * * * 1413 * * * * 2108 * * * * * 25 0 * * * * * * 2335 0 0 G 26 * * * * * 0 * * * * * * * * * * * * * * 26 0 * * * * * * 2335 0 0 I 27 * * * * * * * 2352 * * * * * * * * 1413 1222 * * 27 0 * * * * * * 2335 0 0 I 28 * * * * 2400 * * 1350 * * * * * * * * * * * 1258 28 0 * * * * * * 2335 0 0 Y 29 * * * * * * * * * * * * * * * * * * * 0 29 0 * * * * * * 2335 0 0 P 30 * * * * * * * * * * * * 679 * * * * 1413 * * 30 381 * 2108 * * * * 2335 0 0 V 31 * * * * * * * * * 1048 * 1940 * * * * * 1967 * * 31 0 * * * * 0 * 1974 0 1000 G 32 * * 719 * * 1350 * * * * * * * * * * * * * * 32 0 * * * * * * 2335 0 0 R 33 * * * 2108 * * * * 2347 * * * * * 807 * * * * * 33 0 * * * * * * 2335 0 0 T 34 * * * * * * * 2108 * * * * * * * 2347 2352 1413 * * 34 0 * * * * * * 2335 0 0 Y 35 * * * * 2108 * * * * * * * * * * * * * * 381 35 0 * * * * * * 2335 0 0 A 36 2352 * * * * * * * * 1413 * * * * 2108 2347 * * * * 36 0 * * * * * * 2335 0 0 N 37 * * * * * * * * * * * 381 * * * 2108 * * * * 37 0 * * * * * * 2335 0 0 I 38 2426 * 2108 * * * * 1350 * * * * * * * * 2400 * * * 38 0 * * * * * * 2335 0 0 T 39 * * * * * * * * * * * * * * * * 0 * * * 39 0 * * * * * * 2335 0 0 I 40 * * * * * * * 2352 * 314 * * * * * * * * * * 40 0 * * * * * * 2335 0 0 M 41 * * * * * * * * * 1413 2352 * * * * * 2347 * * 2108 41 0 * * * * * * 2335 0 0 L 42 * * * * * * * * * 316 * * * * * * * * * 2347 42 0 * * * * * * 2335 0 0 S 43 * * * * * * * * * * * 2400 * * * 2352 702 * * * 43 0 * * * * * * 2335 0 0 G 44 * * * * * 381 * * * * * * * 2108 * * * * * * 44 381 2108 * 1000 1000 * * 2335 1000 0 L 45 * * * * 2108 * * * * 1350 * * * * * * * * * 1413 45 0 * * * * * * 2335 0 0 F 46 * * * * 2352 * * * * 2108 * * * * * * * * * 805 46 0 * * * * * * 2335 0 0 P 47 * * * * * * * * * * * * 0 * * * * * * * 47 303 2400 * 2807 222 * * 2335 1000 0 H 48 * * * * 2108 * 2352 * 2347 * * 2400 * * * * * 2426 * * 48 0 * * * * * * 2335 0 0 Q 49 2347 * 2426 * * * * * * * 2400 * * 2352 * * * * * 2108 49 0 * * * * * * 2335 0 0 A 50 1376 * * * * 2426 * * * * * 2347 * * * 2108 * * * * 50 0 * * * * * * 2335 0 0 D 51 * * 1350 * * * * * * 2400 * 2108 * * * 2426 * * * * 51 381 * 2108 * * * * 2335 0 0 K 52 * * * * * * * * 1002 1940 * 2058 * * * * * * * * 52 0 * * * * * 0 1974 0 1000 G 53 * * * * * 396 * * * * * * * * * * * * * 2058 53 0 * * * * * 0 1974 0 1000 K 54 * * * * * * * * 953 * * * * * 2058 * 2039 * * * 54 0 * * * * * 0 1974 0 1000 Q 55 * * * * * * * * * * * 2058 * 953 2039 * * * * * 55 0 * * * * * 0 1974 0 1000 Y 56 * * * * * * * * * 1048 * * * * * * * * * 953 56 0 * * * * * 0 1974 0 1000 I 57 2058 * * * * * * 1967 * 989 * * * * * * * * * * 57 0 * * * * 0 * 1974 0 1000 Y 58 * * * * 2347 * * * * 2426 * * * * * 2400 * 2108 * 2352 58 0 * * * * * * 2335 0 0 S 59 * * * * * * * * * * * * * * * 1350 719 * * * 59 0 * * * * * * 2335 0 0 M 60 * * 2347 * * 1258 * * * 2400 2352 * * * * * * * * * 60 0 * * * * * * 2335 0 0 Y 61 * * * * 2108 2347 * * * * * * * * * * 2426 * 2400 2352 61 0 * * * * * * 2335 0 0 H 62 * * * * 2400 * 679 * * * * 2426 * * * * * * * * 62 704 2347 2400 2000 415 * * 2335 1000 0 M 63 * * * * * * * * * * 2095 * * * 2107 * 906 * * * 63 0 * * * * * 0 2173 0 1000 V 64 * * * * * * * 1892 * 1010 * * * * * * * 2095 * * 64 443 1919 * 2322 322 0 * 2173 1000 1000 N 65 * * * * * * * * 1413 * * 679 * * * * * * * * 65 0 * * * * * * 2335 0 0 D 66 * * 2352 * * * 2108 * * * * 2347 1413 * * * * * * * 66 0 * * * * * * 2335 0 0 P 67 * * * * * * * * * 2347 * * 807 * * * 2108 * * * 67 0 * * * * * * 2335 0 0 F 68 * * * * 0 * * * * * * * * * * * * * * * 68 381 * 2108 * * * * 2335 0 0 I 69 * * * * * * * 1967 * 1048 * * * * * * * 1940 * * 69 0 * * * * * 0 1974 0 1000 S 70 * * * * * * * * * * * * * * * 0 * * * * 70 402 * 2039 * * * 0 1974 0 1000 N 71 * * * 1470 * * * * * * * 646 * * * * * * * * 71 646 * 1470 * * * 0 1781 0 1559 Y 72 * * * * * * * * * * * * * * * * * * * 0 72 0 * * * * 1387 695 1319 0 1778 S 73 * * * * * 1470 * * * * * * * * * 646 * * * * 73 0 * * * * * 0 1802 0 1286 Y 74 * * * * * * * * * * * 1470 * * * 1668 * * * 1624 74 0 * * * * * 0 1802 0 1286 Y 75 * * * * * * * * * * * * 1470 1668 * * * * * 1624 75 0 * * * * * 0 1802 0 1286 T 76 * * * * * * * * * * * * * * * * 1624 566 * * 76 0 * * * * * 0 1802 0 1286 E 77 * * * 646 * * * 1470 * * * * * * * * * * * * 77 0 * * * * 989 1011 1802 0 1286 P 78 * * * * * * * * * * * * 378 * * 2116 * * * * 78 0 * * * * 0 * 2179 0 1000 F 79 * * * * 0 * * * * * * * * * * * * * * * 79 0 * * * * * * 2335 0 0 D 80 * * 1350 * * * * * 2108 * * 1413 * * * * * * * * 80 0 * * * * * * 2335 0 0 N 81 * * 314 * * * * * * * * 2352 * * * * * * * * 81 0 * * * * * * 2335 0 0 G 82 * * * * * 0 * * * * * * * * * * * * * * 82 0 * * * * * * 2335 0 0 F 83 * * * * 1350 * * 719 * * * * * * * * * * * * 83 0 * * * * * * 2335 0 0 V 84 * * * * 1413 * * * * * * * * * * * * 1350 * 2108 84 0 * * * * * * 2335 0 0 V 85 1413 * * * 2108 * * * * * * * * * * * * 1350 * * 85 0 * * * * * * 2335 0 0 R 86 2108 * * * * * * * 1413 * * * * * 1350 * * * * * 86 0 * * * * * * 2335 0 0 I 87 2108 * * * * * * 1350 * * * * * * * * * 1413 * * 87 679 * 1413 * * * * 2335 0 0 G 88 * * * * * 646 * * * * * * * * * * 1470 * * * 88 0 * * * * 989 1011 1802 0 1286 A 89 1108 * * 1895 * * * * 1904 * * * * * * * * * * * 89 0 * * * * * 0 2179 0 1000 N 90 2116 * * * * * * * 1895 * * 999 * * * * * * * * 90 0 * * * * 0 * 2179 0 1000 S 91 2347 * * * * * * * * * * * * 2426 * 696 * * * * 91 0 * * * * * * 2335 0 0 N 92 * * * * * * * * * * * 303 * * 2400 * * * * * 92 0 * * * * * * 2335 0 0 I 93 * * * * 2400 * * 2352 2347 2426 * * * * * * * 2108 * * 93 0 * * * * * * 2335 0 0 T 94 * * * * * * * * 2426 * * * * * * 2400 1350 2108 * * 94 0 * * * * * * 2335 0 0 G 95 * * * * * 1350 * * 2400 * * * * * 2108 * 2426 * * * 95 0 * * * * * * 2335 0 0 S 96 * * 2400 * * 2108 * * * * * 2426 * * * 2352 2347 * * * 96 0 * * * * * * 2335 0 0 S 97 * * * * * 2400 * * * * * * * * * 2352 1386 * 2108 * 97 0 * * * * * * 2335 0 0 V 98 * * * * * * * * * * * * 2426 * * * * 297 * * 98 0 * * * * * * 2335 0 0 V 99 * * * * 2108 * * 1373 * * * * * * * * 2426 2352 * * 99 0 * * * * * * 2335 0 0 G 100 * * * * * 704 * * * * * * * * * 2347 * * * 2400 100 316 2347 * 0 * * * 2335 1000 0 S 101 2426 * * * * * * * * * * * * * * 297 * * * * 101 0 * * * * * * 2335 0 0 A 102 2352 * * 2400 * * * * * * * * * * * * 702 * * * 102 303 * 2400 * * * * 2335 0 0 N 103 * * * * 2107 * * * * * 1892 2095 * * * 1919 * * * * 103 443 * 1919 * * * 0 2173 0 1000 A 104 1624 * * * * * * * 1668 * * 1470 * * * * * * * * 104 0 * * * * * 0 1802 0 1286 T 105 * * * * * * * * * * * 1470 1668 * * * 1624 * * * 105 0 * * * * * 0 1802 0 1286 V 106 * * * * * * * 1668 1470 * * * * * * * * 1624 * * 106 0 * * * * * 0 1802 0 1286 K 107 * * * * * * * * 646 * * * * * * 1470 * * * * 107 0 * * * * * 0 1802 0 1286 K 108 * * * * * * * * 646 * * * * 1470 * * * * * * 108 646 * 1470 * * 1011 989 1802 0 1286 I 109 * * * * * * * 646 * * * * * * * * * * * 1470 109 0 * * * * 980 1020 1781 0 1559 Y 110 * * * * 1048 * * * * * * * * * * * * * * 953 110 0 * * * * 0 * 1974 0 1000 P 111 * * * * * * * * * * * * 381 * * 2108 * * * * 111 0 * * * * * * 2335 0 0 A 112 781 * * * * * * * * * * * * * * * 2426 2108 * * 112 0 * * * * * * 2335 0 0 L 113 * * * * 2347 * * 719 * 2352 * * * * * * * * * * 113 0 * * * * * * 2335 0 0 M 114 * * * * * * * 2108 * 2347 2352 * * * * * 2400 2426 * * 114 0 * * * * * * 2335 0 0 L 115 * * * * * * * 719 * 1350 * * * * * * * * * * 115 0 * * * * * * 2335 0 0 G 116 * * * * * 381 * * * * * 2108 * * * * * * * * 116 0 * * * * * * 2335 0 0 S 117 * * * * * * 2347 * * * * 2108 * * * 807 * * * * 117 0 * * * * * * 2335 0 0 V 118 * * * * * * * * * 2426 * * * * * 1222 2400 2352 * * 118 303 * 2400 * * * * 2335 0 0 V 119 * * * * 1919 * * * * * * * * * * * 1892 1101 * * 119 0 * * * * * 0 2173 0 1000 G 120 * * * * * 351 * * * * * 2211 * * * * * * * * 120 0 * * * * * 0 2526 0 1000 K 121 2218 * * * * * * * 2475 * * 1361 * * * * * 2211 * * 121 336 * 2267 * * * 0 2526 0 1000 F 122 * * * * 2100 * * * * * * * * * * * * 1876 * 1017 122 375 2126 * 0 * * 0 2233 1000 1286 P 123 * * * * * * * 1876 * * * * 459 * * * * * * * 123 0 * * * * * 0 2233 0 1286 S 124 * * * * * * * * * * * * * * 1876 459 * * * * 124 0 * * * * * 0 2233 0 1286 N 125 1876 * * * * * * * * * * 1113 * * * * 1915 * * * 125 0 * * * * * 0 2233 0 1286 K 126 * 1876 * * * * * * 2100 * * 1915 * * 2126 * * * * * 126 0 * * * * * 0 2233 0 1286 T 127 * * * * * * * * 1915 * * 1876 * * * * 1113 * * * 127 0 * * * * * 0 2233 0 1286 G 128 1915 * * * 1876 1113 * * * * * * * * * * * * * * 128 0 * * * * * 0 2233 0 1286 R 129 * * * 1876 * * * * 1915 * * * * * 1113 * * * * * 129 0 * * * * 989 1011 2233 0 1286 Y 130 * * * * 2241 * * * * 2213 * * * * * * * * 2226 1478 130 0 * * * * * 0 2538 0 1000 F 131 * 2213 * * 1347 * * * * 2477 * * * * * * * 2241 * * 131 0 * * * * * 0 2538 0 1000 N 132 * 2226 2213 * * * * * * * * 810 * * * * * * * * 132 0 * * * * * 0 2538 0 1000 H 133 * * * * * * 1478 * * * * 2213 2226 * * * 2241 * * * 133 0 * * * * * 0 2538 0 1000 T 134 * * * * * * * * * * * * 2213 * * 2241 804 * * * 134 0 * * * * * 0 2538 0 1000 L 135 * * * * 2213 * * * * 1478 * 2226 * * * * * * * 2241 135 0 * * * * * 0 2538 0 1000 V 136 * * * * 2213 * * * * * * * * * * 2241 * 804 * * 136 0 * * * * * 0 2538 0 1000 I 137 2213 * * * * 2226 * 810 * * * * * * * * * * * * 137 0 * * * * * 0 2538 0 1000 L 138 * * * * * * * * * 1478 * * * * 2226 * * 1227 * * 138 0 * * * * * 0 2538 0 1000 P 139 * * * * * * * * * * * * 804 * * 2213 * 2241 * * 139 0 * * * * * 0 2538 0 1000 E 140 * * 2477 1355 * * * * 2213 * * * * * * * * 2226 * * 140 0 * * * * * 0 2538 0 1000 K 141 * * * * * 1346 * * 2479 * * * 1227 * * * * * * * 141 0 * * * * * 0 2538 0 1000 C 142 * 1478 * * * * 2241 * * * 2213 * * * * * 2226 * * * 142 0 * * * * * 0 2538 0 1000 G 143 * * * * * 343 * * * * * * * * * * 2241 * * * 143 0 * * * * * 0 2538 0 1000 T 144 * * * * * * * * * * * * * * * 2241 799 2226 * * 144 0 * * * * * 0 2538 0 1000 Q 145 * * * * * 2226 * 2477 * 2241 * * * 1340 * * * * * * 145 0 * * * * * 0 2538 0 1000 I 146 * * * * * * * 726 * 2477 * * * * * * 2213 * * * 146 0 * * * * 0 * 2538 0 1000 T 147 * * * * * 2384 1526 * * * * 2683 * * * * 1711 * * * 147 0 * * * * * * 2664 0 0 A 148 1685 * * * * 2683 * * * * * * * * * 2722 2394 2384 * * 148 244 * 2683 * * * * 2664 0 0 L 149 * * * * 2461 * * * * 2475 2211 * * * * * * * * 1243 149 0 * * * * * 0 2526 0 1000 Y 150 2218 * * * * * * 2211 * * * * * * * * 2267 * * 1468 150 351 * 2211 * * * 0 2526 0 1000 C 151 * 1099 * * * * * * * * * * * 1912 * * * 1903 * * 151 0 * * * * 980 1020 2183 0 1559 V 152 * * * * * * * * * * * 2385 * * * * 2112 793 * * 152 0 * * * * * 0 2349 0 1000 L 153 2112 * * * * * * * * 380 * * * * * * * * * * 153 0 * * * * * 0 2349 0 1000 Q 154 * * * 2420 * * 2333 * * * * * * 702 * * * * * * 154 0 * * * * * 0 2349 0 1000 P 155 2112 * * * * 2385 * * * * * * 793 * * * * * * * 155 0 * * * * * 0 2349 0 1000 K 156 * * * * * * * * 2382 2385 * * * * 2333 2112 * * * 2420 156 0 * * * * * 0 2349 0 1000 N 157 * * * * * * * * * 2385 * 1401 * * * * 2333 * * 2112 157 0 * * * * * 0 2349 0 1000 Q 158 * * * 2112 * * * * * * * 2420 * 782 * * * * * * 158 0 * * * * 0 * 2349 0 1000 T 159 * * * * 2394 * * 1702 * * * * * 2670 * * 1533 * * * 159 0 * * * * * * 2664 0 0 N 160 * * 2394 * * 2384 * 2722 * * * 1685 * * * 2683 * * * * 160 0 * * * * * * 2664 0 0 C 161 * 1685 * * * 2384 * * * * 2722 2394 * * * * * 2683 * * 161 0 * * * * * * 2664 0 0 T 162 1003 2683 * * * * * * * * * * * * * 2384 2700 * * * 162 0 * * * * * * 2664 0 0 G 163 * * * * 2394 993 * * * * * * * 2683 * 2722 * * * * 163 0 * * * * * * 2664 0 0 H 164 2384 * * 2670 * * 2700 * * * * 2394 * * * * * 2722 * 2683 164 0 * * * * * * 2664 0 0 T 165 * 1549 * * * 2384 * * * * * * * * * * 1099 * * * 165 0 * * * * * * 2664 0 0 T 166 * * * * * 2384 * * * * 2683 2670 * * * * 1013 * * * 166 0 * * * * * * 2664 0 0 Y 167 * 2683 * * 1526 * * * * * * * * * * * * * * 1009 167 0 * * * * * * 2664 0 0 T 168 * * * 1531 * * * * 2670 * * * * * * * 1009 * * * 168 0 * * * * * * 2664 0 0 S 169 * * * * 2384 * * 2722 * * * * * * * 1685 * * * 1531 169 0 * * * * * * 2664 0 0 Y 170 * 2722 * * * * * 2394 * 2670 * * 2683 * * 2384 * * * 2700 170 0 * * * * * * 2664 0 0 V 171 * * * * * * 2683 * * * * * * 2722 * 1526 * 1533 * * 171 0 * * * * * * 2664 0 0 L 172 * * 2394 * * * * * * 1112 * * * * * 2384 2683 * * * 172 0 * * * * * * 2664 0 0 V 173 2394 * * * * * * 2683 * * * * 1543 * * * * 2700 2670 * 173 237 2722 * 2322 322 * * 2664 1000 0 E 174 * 2683 2670 2700 2394 * * * 2384 * * * 2722 * * * * * * * 174 0 * * * * * * 2664 0 0 N 175 * * * * * * 1526 * * * * 1711 * * * 2394 2670 * * * 175 307 2384 * 0 * * * 2664 1000 0 K 176 * * * * * * * * 2700 2394 * * 1677 * * * 1543 * * * 176 247 2670 * 3170 170 * * 2664 1000 0 N 177 * * 2394 * * * * * * * * 304 * * * * * * * * 177 0 * * * * * * 2664 0 0 L 178 * * * * * 2722 * * * 997 * * * 2670 * * * 2394 * * 178 244 2683 * 0 * * * 2664 1000 0 K 179 * * * 2670 * * * * 2700 * * 1702 * * * 2394 2384 * * * 179 0 * * * * * * 2664 0 0 Q 180 2670 * * 2394 * * * * * * * * * 1691 2722 * * * 2384 * 180 0 * * * * * * 2664 0 0 S 181 * * * * * * * * 2394 * * * * * 2683 1533 2670 2722 * * 181 0 * * * * * * 2664 0 0 L 182 * * * * * * * 1702 * 993 * * * * * 2394 * * * * 182 0 * * * * * * 2664 0 0 Q 183 * * * 2683 * 1003 * * * * * * * 2700 * * * * 2384 * 183 247 2670 * 1585 585 * * 2664 1000 0 T 184 * * * * 2722 * * * * 2683 * 2394 * * * * 2700 1520 * * 184 0 * * * * * * 2664 0 0 W 185 * * * * 2394 * 2384 * * * * * * * * * * * 1117 2670 185 0 * * * * * * 2664 0 0 F 186 * * * * 1685 * 1702 * 2394 * * * * * 2384 * * * * * 186 997 1003 * 2145 370 * * 2664 1805 0 D 187 * * 694 * * * 2394 * * * * * * * * * 2384 * * * 187 0 * * * * * * 2664 0 0 L 188 * * * * * * * * * 997 * * * * * * * 1003 * * 188 0 * * * * * * 2664 0 0 K 189 * * * * * * * 2670 1711 * * * * * 1389 * * 2683 * * 189 0 * * * * * * 2664 0 0 D 190 * * 2700 2394 * * * * * 2384 * 2670 2722 * * 2683 * * * * 190 237 2722 * 1000 1000 * * 2664 1000 0 C 191 * 304 * * 2394 * * * * * * * * * * * * * * * 191 0 * * * * * * 2664 0 0 L 192 * * * * * * * * * 1117 * * * * 2384 * 2670 2394 * * 192 0 * * * * * * 2664 0 0 F 193 * * * * 997 * * * * 2722 * * * * * * * * 2384 2683 193 0 * * * * * * 2664 0 0 E 194 * * * 2700 * * * * 1549 * * * * * 1677 * * * 2384 * 194 0 * * * * * * 2664 0 0 K 195 * * * * * * * * 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0 0 N 309 * * 3444 3750 * * * * * * * 3751 1570 * * 1995 2541 * * * 309 0 * * * * * * 3635 0 0 S 310 * * 1995 * * * * * 3444 * * * 3345 * * 3751 1046 * * * 310 0 * * * * * * 3635 0 0 G 311 * * * * * 0 * * * * * * * * * * * * * * 311 134 * 3492 * * * * 3635 0 0 V 312 * * * * 1405 * * 3319 * * * * * * * * * 938 * * 312 0 * * * * * 0 3508 0 1000 Y 313 * * * * * * * * * * * * * * * * * * * 0 313 0 * * * * * 0 3508 0 1000 S 314 3444 * 2500 3654 * * * * * * * * 2400 3319 * 1465 * * * * 314 0 * * * * * 0 3508 0 1000 A 315 3615 * * * * * * 3394 * 1975 * 3254 * * * * 1803 2493 * * 315 139 3444 * 0 * * 0 3508 1000 1000 S 316 3405 * 3394 * * * * * * * * 2509 * * * 656 * * * * 316 0 * * * * * 0 3508 0 1000 Y 317 * * * 3254 * 2634 * 3377 3405 3444 * 3319 * * 3424 3619 3394 * * 3615 317 0 * * * * * 0 3508 0 1000 F 318 * * * * 1151 * * * 3377 * * * * * * * * 3254 * 1520 318 0 * * * * * 0 3508 0 1000 N 319 * * * 2425 * * * * * * * 3615 * 3444 2370 * 1507 3394 * * 319 0 * * * * * 0 3508 0 1000 A 320 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2155 * * 3211 3057 3247 * * * 487 182 3079 * 1000 1000 1456 654 3126 1000 2037 D 488 1727 * 3430 * * * * 3199 3446 * * * * * * 3309 1720 * * * 488 139 * 3446 * * * 0 3304 0 1549 V 489 * * * * 3120 * * 3318 * 3030 * * * * * 2233 2202 2106 * * 489 0 * * * * * 0 3230 0 1991 D 490 * * 3087 * * * 3318 3126 3323 * * 2074 * 3090 * 3261 3206 * * * 490 0 * * * * * 0 3230 0 1991 Y 491 * 1774 * * * * * * 3233 * * 3260 * 3393 3453 * * * * 1688 491 0 * * * * 1446 660 3364 0 1991 F 492 3372 * * 3559 2435 * * * * * * * * 3443 * * 2462 * * 1473 492 156 * 3290 * * * 0 3422 0 1549 G 493 2306 1300 * * * 3367 * 3350 * * * * * 3383 * * * 3310 * * 493 0 * * * * 0 * 3265 0 2037 Y 494 * * * * * 3702 3636 * * 3584 * * 3757 * * 2848 * 3642 2025 2180 494 0 * * * * * * 3729 0 0 N 495 * 3880 * * 3612 * 3850 3757 * 3846 * 3847 3543 * * 2030 * * * 2075 495 0 * * * * * * 3729 0 0 F 496 * * 3612 * 3847 * * * * 2564 * * * 3880 * 2141 * 3642 2086 3849 496 120 * 3642 * * * * 3729 0 0 N 497 * * 3717 * * * * * * * * 559 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* * 3154 * 3303 * * * * * 2292 2409 * 3156 * 507 0 * * * * 1482 639 3461 0 1973 Y 508 * * * * * 3287 * 3607 * 3652 * 3421 * * 3289 * * * 2422 1500 508 143 * 3409 * * * 0 3515 0 1557 T 509 * * * * * * * 3128 3276 * * * * * * * 1082 * * 1690 509 172 * 3155 * * * 0 3372 0 1935 P 510 2917 2416 * * * * * * 1994 * * * 2396 3115 3014 * * * * * 510 0 * * * * 1969 426 3104 0 2253 R 511 * * 3128 3454 * * * * * * * * 1697 * 2301 3499 * 3451 3276 * 511 371 * 2139 * * * 0 3372 0 1935 T 512 * 3137 * 2945 2735 * * * * * * * * 2004 * * 1487 * * * 512 174 * 3141 * * 2310 325 2863 0 2652 S 513 * * 2923 2819 * * * * * * * 1991 * * * 1458 3171 * * * 513 170 3171 * 3585 126 * 0 2937 1000 2622 E 514 * 1984 * 1954 * * * * 2107 2923 * * * 2997 * * * * * * 514 0 * * * * 2267 336 2937 0 2622 G 515 * * * * * 574 * * * * * * 3109 3112 * * * 3372 * * 515 187 * 3037 * * * 0 2997 0 2349 S 516 * * * * * * * 2887 * 1828 * 3136 * 3133 * 2152 * 2938 * * 516 0 * * * * 2335 319 2834 0 2659 I 517 * * * * 3096 * * 1753 * 2096 * * * * * * * 1504 * * 517 0 * * * * 1847 470 2973 0 2367 Q 518 * * * * * * * * 3445 * * * * 1857 3131 * * 3458 * 1228 518 138 3452 * 4585 61 * 0 3306 1000 1951 M 519 * * * * 3458 3249 * * * * 2437 * * 3452 3172 2186 3445 * * 3248 519 0 * * * * * 0 3306 0 1951 V 520 2452 * * * * * * 3445 * 2189 * * * * * * 3248 1760 * 3243 520 139 * 3445 * * 1602 577 3306 0 1951 Y 521 3309 * * * 1729 * * * * * * * * * * * 3535 2254 * 1730 521 0 * * * * 1417 677 3447 0 1962 V 522 * * * * * 3391 * 2623 3623 * * * * 3399 * * * 820 * * 522 122 3626 * 3807 107 * 0 3498 1000 1483 I 523 * * * * * * * 1176 * 3331 * 3611 * * * 3251 2507 3391 * * 523 0 * * * * 0 * 3498 0 1483 T 524 * * 3849 * 2740 3702 * * * * * 3642 * * * 2126 2047 3846 * 3584 524 126 3584 * 1000 1000 * * 3729 1000 0 A 525 2864 * * * 2592 1365 * 3612 * 3636 * * * * * * 3702 3850 * * 525 0 * * * * * * 3729 0 0 N 526 3441 * 1363 3543 * * * * 3636 * * 2864 * 2774 * 3849 * * * * 526 0 * * * * * * 3729 0 0 Y 527 * * * * 2058 * 3846 * * 3543 * 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