HHsearch 1.5 NAME c9jmiC_ FAM FILE c9jmiC_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9jmiC_.a3m DATE Sat Jun 21 11:45:42 2025 LENG 1131 match states, 1131 columns in multiple alignment FILT 20 out of 22 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 3.2 EVD 0.3203 -9.5005 SEQ >ss_pred CCCEECCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEECCCCEEEEEECCCCCCCCCEEE ECCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCEEEEECCCCCEEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEEEEECEEEEEEEEE ECCCCEEEEEEECCCCEEEEEEEECCCCCCCCEEEEEEEEEEEEEEEEEEEECCCCHHHHHHCHHHEEEECCCEEEEEEEECCCEEEEEEECCCCHHHHC EEEEEEECCCCCEEECCCEEEEEEEEEEECCCCCCCCCCHHCCCCCCCCCCCCCEEECCCEECHHHEEEEEEEEEECCCCCCHHHHHCCCCCEEEEEEEE EECCCEEEECCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC EEEEEECCEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCEEEEEECCEEEEEEEEECCCCCCEEEEEEECCCEEEEEECCCCEEEEEECCC CCEEEEEECCCCCCEEEECCCCCCCEEEEEEEECCCHHCCCCCCCCCCCEECCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCE EEECCCCCEEEECCCEEEEEEEEEEEEECCCEEEEECCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC CEECCCCCCCCCHHHHHHCCEEEECCCCCHHHHHHHHHCCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHH HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCEEEEEEEEEEEECCCCEEEECCCCEEEEECCCEEEEEECCCC CCCCCCCCCEEEEECCEEEEECCCCCCCCCC >ss_conf 9010016441023465442122342148753613410022343114333556505786401101562003456632010482899980345211352342 0345543100168970332343235642110563156662754224468998502210112433124410126775555268898873001026545655 1368713413664785189998521684035212024666211124567640112623310010100342032047788606751776763473002001 1234310168874112412543025899535766586201003677665543002312411221320120000020147767455401101102311345 3055213320377300012464456667522688763156765423233566300100034677420002563657643333223343310234204772 0365201022133456414799971233667667667665522220521468862068899997211000004899622866669805885899960686 6336895057765224520200241356532200100001224666520001111677630654546777611132455405674334543313666430 1221676368944530688887799865352599613144088279999999998998999999988667767888988732110014444455677644 1002467776304431210226851764056688775356404634532376267678879889999999998500024768789999998614022338 9999889999999999999999998999999999999998558999999999751113468789999999987665201345556678999999999999 9999999999999999899761211025446876899980249981899999764787599998545762387115763684489805984999521211 4403763336996052599603666588789 >Consensus xxxxxxqpxyxxxxxxxxxxxsxxxgxxyxxxxxyxnxtlxltgxxpxxxxxxxxxxxtxxxxxxxxfxsxxxxxxxpfxdgxxxxxxxxxnxxxxxvxx sxxxxxxxxxpxxxigxxxgxxxxxxxxxxxxxtxxxxxxxxgtxixxxxxxlxxxxxxxxxxxxxyxxxxxxxxxxnxxxxxxxxxdxxxcxxxxxfxx xxxxxxxxfxxxqxxxxxyxyxxxxxgxxxxxxfxfxxlxxgxxlxxxxxxpxsxxxxxxxxxxxxxVxxLxxxxxLvxfdxxGxixxavDCxxxxxxxL xCxxxsFxxxtGvYxxsxxxxqpxgxxxvxxxlxxCxxxvxxxxxxpxxxnxxRxxfxnCxxNxtxlxxxxxxxxxxcxxvxpsxlxxxCxxsvxxDxfx ixxsxxxxlxxgxxgxxxxfnykxxxaxxxcxxxxtixxxxtxxxxxxxnxxyxxxxxcfxxxxxxxxxxxxxxxxxxcxxxxxxxxxxxxxxxxxxnxx xxxxgxxxxxxxxxxxxxqxlxvixxxxxxxxxxvcxvxdxsxxxxdxCvxYnIYGxtGxGvixxxnxxxxxxlxyxssGxllgfxxxtgxxyxVxPCxx xxxxvvxxxxsxxxxxlxxxxxcsxxxxxxxxxsxxxxxxxxxxxxxxfxtxxgcxxxxxxxxxtxxnCxxplxxsxcxxxxxxxxxxvxxxxxxxxxxx xxxxxxxxxixIPtnFtlsvtxEyiQtxxxkVsIDCxxYVCngnxrCxxLLxQYgsfCxxIexaLxxvxxlxdxxxxxlxxxxxxxxxxxxxsxfxgdyN xsxlxxxxxxRSaIEDLLFdKVxtsglGtvxdYkxCtxxDLxCAQyYNGImVLPgVvdaexmAmYTasLxggmxxggxTAaAIPFaxavQaRlNylaltt xVLxeNQkiiAnsFNxAigxIqxgFxtvsxALxKIQdVVNxqaxALxxLxxQLsnNFgAISsSIxdIyxRLDxleAdaQVDRLItGRLtALnafVtQxLx xxxevrxSrxLAxqKINECVKSQSxRyGFCGNGtHixSlxqxAPnGixFxHxxlvPtxxvxVxaxxGlCvxxxxxxixxkxgxfixxxnxxwxiTxrxxy xPxpitxxnxxxxsxxvxxxnxtxxxxpplx >c9jmiC_ CIVVDMQPSYFQRDWPRPINMSAADGIIYPVGRTYANITIMLSGLFPHQADKGKQYIYSMYHMVNDPFISNYSYYTEPFDNGFVVRIGANSNITGSSVVG SANATVKKIYPALMLGSVVGKFPSNKTGRYFNHTLVILPEKCGTQITALYCVLQPKNQTNCTGHTTYTSYVLVENKTNLKQSLQTWFDLKDCLFEKKYNV SADEREEWFGITQDQQGVHLYTSRKNGFKSNNMFLFATLPIYERLRYYTVMPRSIKTNDHMAWSAFYIYQLHKLNYLVEFDVEGYIVRASDCGANDYTQL QCSYGQFDMNSGVYSASYFNAQPRGYYYVANELEECALDVLFKNIAPQIANYSRRVFTNCNYNLTKLLSLVEVDEFVCDKTTPESLATGCYSSLVVDWFA LPLSMKSTLAIGSAEAISMFNYNQDYSNPTCRIHATINSNVSSSLNFTANNNYAYISRCQGTDGKPILLQKGQLPNIACRSGVLGLSNDVDYFGYNFNGR IFYIGRKSYTPRTSEGSIQMVYVITANYAEGPNNVCPLKDNLDSLLGQCIDYDINGVVGQGVFQKCNSIPSQVFVYDSFHNIIGYHSKNGTYYCMAPCVS VPVSVIYDKSSNSHATLYGSVACDHIKMIPSVLSRETATKLRASDNGLLQTAVGCVIGFHNTSDTVEDCNLPLGQSLCAKPPSNNTFGLAVMKYENPLKV EVLNSSEFEISVPTNFSFRVTEEFIETSIQKVTVDCKQYVCNGFERCEQLLEQYGQFCAKINQALHGVNLRQDDATKSLFESIRVPQSAPLMASLSGDYN LSLFETPGNYRSALEDLLFDKVTLSVPGYMKGYDECMKKDLICAQYVAGYKVLPPLYDSNMEAMYTASLTGSIAGALWTAASLPFAQSIYYRMNGIGITQ NVLMENQKLIANKFNQALGAMQTGFTTTNQAFQKVQDAVNANAQALSKLASELSNTFGAISASIGDILKRLDTLEQEVQIDRLINGRLTSLNAFVSQQLV RSEAAARSSQLVKDKVNECVKSQSSRNGFCGQGTHIVSFAVNAPNGFYFVHVGYHPTDYVNQTSAYGLCDSSNTKCIAAKNGYFIKNGSDDWMFTGSSYY QPEPITNFNSRSVEPEVTFQNLTNNLPPPLS >UniRef50_A3EXG6(137-1123:1274) Spike protein S2 n=4 Tax=Rousettus bat coronavirus HKU9 RepID=SPIKE_BCHK9 E=1e-152 s/c=0.55 id=34% cov=71% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -------------------------------------------------------------------VAHLINRDLLVSYFNNGSVANAADCADSAAEEL YCVTGSFDPPTGVYPLSRYRAQVAGFVRVTQRGSYCTPPYSVLQDPPQPVVWRRYMLYDCVFDFTVVVDSLPTHQLQCYGVSPRRLASMCYGSVTLDVMR INETHLNNL----------FN--------------RVPDTFSLYNYALPDNFYGCLHAFYLNSTAPYAVANRFPIKPGGRQSNSAFIDTVINAAHYSPFS YVY----------------GLAVITLKPAAGSKLVCPVANDTVVITDRCVQYNLYGYTGTGVLSKNTSLvipDGKVFTASSTGTIIGV-SINSTTYSIMP CVTVPVSVGYHPNF-ERALLFNGLSCSQRSRAVTE-PVSVLWSASATAQDAFDTPSGCVVNVELRNTTiVNTCAMPIGNSLCfingsiATANADSLPRLQ LVNYDPLYdnsTATPMTPV-YWVKVPTNFTLSATEEYIQTTAPKITIDCARYLCGDSSRCLNVLLHYGTFCNDINKALSRVSTILDSALLSLVKELSINT RDEVTTfSFDGDYNFTgLMGCLGpncgatTYRSAFSDLLYDKVRITDPGFMQSYQKCIDsqwggsiRDLLCTQTYNGIAVLPPIVSPAMQALYTSLLVGA VASSGYTfgitsAGVIPFATQLQFRLNGIGVTTQVLVENQKLIASSFNNALVNIQKGFTETSIALSKMQDVINQHAAQLHTLVVQLGNSFGAISSSINEI FSRLEGLAANAEVDRLINGRMMVLNTYVTQLLIQASEAKAQNALAAQKISECVKAQSLRNDFCGNGTHVLSIPQLAPNGVLFIHYAYTPTEYAFVQTSAG LCHNGT--GYAPRQGMFVLpNNTNMWHFTTMQFYNPVNISASNTQVLT----------------- >UniRef50_A8JP00(42-996:1128) Spike glycoprotein n=3 Tax=Rhinolophus bat coronavirus HKU2 RepID=A8JP00_9ALPC E=1e-98 s/c=0.38 id=29% cov=81% ---------------------------------------------------------------------------------------------------- -------------------GAYPSTNKAKWFCPTNVGRPVGTGVGIGVYAQTAQASYETGGSGAGGYTFSVSPKHVTNLTWSLWVHRpwgananvTVRLC RWWQKFSFNETAHFQPAGpssafeclvngsFPSSQHKGYMFGVTWYNDFVRIIFPPTVFELQVDGLQWEYVQFTGPVNAGRMTKFNVVTEISSV--LVLT DQSGAVTRYSYCADGFVNGLQCKLRLFDIPPGVYSNSEVEY-PVALYTVVHNMSVCPQRP-ESYCGSNYCPFKRVVFSNCVVNYTSwtsgLLRDYQHLVL PNGKFNP---FTECNG----------LNRIVD---------------------DCVTGFVLRVGRGTAVNRTVITPYLKPNECFG--------------- ------------------WSWNDYQDSI-YDWWIAD---------FVSTGAFVCEKNPDAP-------RTGVCITYTIEKVTFQGVLYESNFTFAQYYNV LYFGSQLKYVRILGKVYEVAPCFEASYDVLF-RSSSSFGLLYRSFDCNQLRISASRF----AERLLPSHNGT-ATALGCLFNATYAPnDTMVNCTNPLGD GFCADLLSNVV--VRRMTFEKHDTtyVAPVTIERF-TELPLDHQLVLTEQFLQTTMPKFSISCETYICDVSKACKNLLFRYGGFCQKIEADIRGAGVLLD SDVSGLYSTIAAKTSSIMPT--TDRFNVSQFFLPKvqstserfESRSVIEDLLFSKIETTGPGFYGDYYNCKKnaiQDLTCAQYHNGILVIPPVMDAETL GMYGGIAAASLTLGIFggQAGITTWSLAMAGRLNALGVVQNALVDDVNKLANGFNQLTASVSKLALTTSSALQAIQAVVNQNAAQVESLVSGITENFGAI STNFKVISQRLDKLEADVQMDRLINGRMNVLQLFVTNYKLKIAELRNTHRYVQSLINECVYAQSLRNGFCGQGLHVLSLMQNAPSGIMFFHYSLIPNNTI IVKTTPGLCESDElgSKCIVAKDGVLVSANLSYWQWSPRNLYKPENLTFANVIAVSRGANYTTLNRTFDIP-- >UniRef50_B6VDX8(224-1046:1192) Spike glycoprotein n=1 Tax=Thrush coronavirus HKU12-600 RepID=B6VDX8_9GAMC E=3e-96 s/c=0.43 id=32% cov=67% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------CDKDLYDHL RCQQSSFSLTDGFYSTAKYTTnQQRKTIFV--TLPK----HTYTETISILPNISNPAYPDGSTNGPALGWWVGTMNVLFNNSQ-----TLCVNS---SFF MVNITFKCWLKPHPTK--PSDEYKCIGGLPTAQVKLP-------DWPFA-----------------PYYSFSQ-----LCLSSTYQVGYSTFYFQYWNQG TNKRWESKPLFYYTYQTGTQYTYV--------TKPVISFTDVSELSLYECVDYNIYGVIGSGIIQPSNISYLNGLYYTSSaGQLLAFKnSTTFQIYTVQP C-----------DSPGQVIVYNN---SFIGAITA--SNQTILNFKSRIATPTFYY------HTNATSVQGNCNTaPLQFSSIGICPDGSIMQVNTTVDTL PATTIITSGN---ITIPLNFTISIQAEYLQIQAQHTVVDCQTYVCNGNAKCLQLLQQYSTACSNIEQSLTMSARLDNAETLAMVQTSTQGYHLSKIEQHD NQYNLTaILPNKQGGRSAIEDLLFDKVVTNGLGTVdQDYKECTKgvslADLACAQYYSGIMVLPGVVDAEKMAMYTASLTGGMFFGGLTAAsSIPFSVAV QARLNYVALQTDVLQKNQQILANSFNQAMGNITLAFSSVNdalqqtseviqtvaNALNKIQDVVNKQGSALNHLTLQLQNNFDAISHSIADIYARLDEVE ANQQVDRLITGRLAALNAYVTQVLTQISQLKAQRQLAQEKINECVKSQSDRFGFCGNGSHLFSITQAAPNGILFLHTVLTPTDRVQVNAIAGICVSDSAF VLREPNLAFFQH-DGKWLISPRRLFQPRPATVADFVQIqSCEVTFYNTTYDELPQL- >UniRef50_B3FHU5(206-1024:1226) Spike n=17 Tax=Coronavirinae RepID=B3FHU5_CVTKE E=9e-96 s/c=0.43 id=33% cov=64% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------INKL RCAYQQFNFSTGFYDIDTFVPVTSNITYLPyPDLKDntgqevCDFYVALKG-------------DHVIYNQSCVDSKYPFFKLKCNNT----------YS WDNDKLCI---------LGSEIYVPGYNV---YTNTQHSYAGTIPNYPTCSSKGLSleniYNNIGFNRFCVTKLLTTRDISSITQYTCVYVVSVEGFDSY NQGIVYSYVGVNFDFGTAMYSVKTAP--MQFIY-----------------------TEQCHKYNIYNIRGVGQILNVTGKDNTTlvdggLVITSGSGLLA FRN-NGSLFSVQPCRTVSTQAVI--VNGSFVGLFVPASCwladqfnlgNHTEYVDGgcLISNKTISRKRRSTNAVYTGECTGLFAAMGTSCIYSNGTV-L NRTL---PQPSVQTSVQ------PLLGVVAN-----VSIPKELTLAVTTEYLQTRYQKVTIDCAKYVCGDSTRCRTLLQQYGSFCQSVNAILSGVNENED NGllqyAEAINTGYTLNFTGYNVSNLGGfdlslvlPKNLTLAQNQG--RSTIEDLLFDKvVTLGVSEVDQNYDKCIASrggsftnlaDLTCAQFYNGVMV LPGVVDPGLMAVYTGSLIGGMALGGITAAAsIPFATQIQARVNYLALTQSVLLDNQNLIANSFNKALKGIQSaldtvsqgfvevarGFESVTVALNKVQD VVNTHSDILNKLMAQLSVNFGAVSSSLNEIYLKLDQINADAQVDRLITGRLTALSTYVASLQLAAYKADQSRRLALQKVEECVKSQSMRYGFCGNGSHVL TIPQSAPNGIFFIHYTYQPTSYVTIEAVPGLCVTTPSGkyGVMPKTGSgIIFRQNDTFFVTSTQLYEPK---------------------------- >UniRef50_B2BW33(468-1268:1472) Spike protein n=1 Tax=Beluga Whale coronavirus SW1 RepID=B2BW33_9GAMC E=2e-95 s/c=0.44 id=31% cov=67% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -------------------------------------------------------------AMPQTFISTLNYTTALVTFD-KGNVRSVIDCNSEKpFDR LRCDLQTDVVSDGFYPVNIKTNEAKentTFIDVPATLANLTLEVFVSSPEQSPA---------CVIKSYKCVDtryfYISDYSYSCaENGIPNDAAGAAY CRGVLD------------QINNYGVRGMdFKGKCPFAGS------------------KVNSGLTFDKICFGV------YEQGCQSDKACRFGF------- ----YFDNVQFSQYGNKLYYKP------QDLGFIDYQFGTLFKNS-LVQSNI--IQEGCHDYDIYGYKGTGVvkpFSDYSYLQTGGLIMLDSGGFPSLFR YNFALYEVTQCTREVAQLAVASNNAIGYYLPKQVTIDGVNASTS------CNTTGAFKYCYYDDVIHVGRDVSNVTINVCNPSLMMENSHCINIQGNFMV NEPAITFNSTQYQPLLGVSG-DVQLPRTLMLHTTTEFIQTHSPKIVIDCTKYVCGSSERCRRILVKYGGFCESIMRLLNGVNMADDVSVTDFLDnfnsfd niSVSLQNLNASFGQFEG-YGFQKFlpksfdfdgSDPRDARSTIEDILFDKVTTVGLGTVDAdYDKCTKglsvADLVCAQYYNGIMVLPGVADAEKMAMY TGALVGGmVLGGITSAAAIPFATQIQARVNYLALTQNAIQENQKIIVQQFNKAIDSMtsafqsvNEGFSAVSSAITEVQNAVNAQSQALTKLLGQLNYNF GATTSSIKELYERLAKLEADVQVDRLINGRLTALSAFVAARQVEAAKVASQRVLAAEKINECVKSTSNRYGFCGNGAHIISFPQNAPNGMLFVHFSLVPN ETITVKGIIGLCLNNSIGIVPAKDrGMFIQCSNGTY--------------------------------------- >UniRef50_Q65984(386-1300:1453) Spike glycoprotein n=344 Tax=Alphacoronavirus RepID=SPIKE_CVCAK E=5e-95 s/c=0.38 id=31% cov=75% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ----------------SFYSYGEISFGVTDGPRYCFA-LYNGTALKYLGTLPPSVKEIAISKWGHFYIN-----------------------GYNFFSTF PIDCISFNLTTG----------DSGAFWTIAYTSYTDALVQVENTA-----IKKVTYCNSHINNIKCSQLTANLQNGFYPVASSEVGLVNKSVVLLPSFY SHTSVNITIDLG----MKRSGYGQPIASTLSNITLPMQDNNTDVYCIRSNRfSVYFHSTCksslwddvFNSDCTDVLYATAVIKTGTCPFSFDKLNNylT FNKFCLSLNpvgaNCKFDVAARTRTNEQVVRSLYVIYEEGDNIVGVPSDNSGLHDLSVLHLDSCTDYNIYGITGVGIIRQTNSTLLSGLYYTSlSGDLLG FKNvSDGVIYSVTPCDVSAHAAVIDGAIVGAMTSINSelLGLTHWTTTPNFYYYSIYNYTNERTRG----------TAIDSNDV--DCEPIITYSNIGVC KNGALVFINVTHSDG--DVQPISTGN--VTIPTNFTISVQVEYIQVYTTPVSIDCSRYVCNGNPRCNKLLTQYVSACQTIEQALAmgarlenmEIDSMLF VSENALkLASVEAFNSTETLDPIYKEWPniggswlgglkdiLPSHNSKRKYRSAIEDLLFDKVVTSGLGTVdEDYKRCTGgydiADLVCAQYYNGIMVLP GVANDDKMAMYTASLAGGITLGSLggGAVSIPFAIAVQARLNYVALQTDVLNKNQQILANAFNQAIGNITQAFGKVNDAihqtsqglatvakvLAKVQDV VNTQGQALSHLTLQLQNNFQAISSSISDIYNRLDELSADAQVDRLITGRLTALNAFVSQTLTRQAEVRASRQLAKDKVNECVRSQSQRFGFCGNGTHLFS LANAAPNGMIFFHTVLLPTAYETVTAWSGICASDGDRtfGLVVKDVQLTLfrNLDDKFYLTPRTMYQPIVATSSDFVQIEGcDVLFVNAT-------- >UniRef50_Q8BB25(41-1227:1349) Spike protein S2 n=85 Tax=Betacoronavirus RepID=SPIKE_CVP67 E=0 s/c=0.89 id=34% cov=94% ------------------VDVTNGLGTFYVLDRVYLNTTLLLNGYYPisgatfrNMALKGTRLLSTLWF--KPPFLS-------PFNDGIFAKV-KNSRF SKDGVIYSE-------FPAITIGST-----------FVNTSYSIVVEPHTSLING---NLQGLLQISVCQYTMceYPHTICHPNLGN--QRIELWHydtD VVSCLYRRNFTYDVNADYLYFHFYQEGGTFYAYFT-DTGFVTKFLF---KLYLGTVLSHYYVMPLTCNSALSL---EYWVTPLTTRQFLLAFDQDGVLYH AVDCASDFMSEIMCKTSSITPPTGVYELNGYTVQPVAtVYRRIPDLPNCDIEAWLnSKTVSSPLNWERKIFSNCNFNMGRLMSFIQADSFGCNNIDASRL YGMCFGSITIDKFAIPNSRKVDLQVGKSGYLQSFNYKIDTAVSSCQLYYSLPaanVSVTHYNPSSWNRRYGFNNQSFGSRGLHDAVYSQQCfntPNTYCp crtsqciggagtgtcpvgttvRKCFAAVTKATKCTCWCQPDPSTYKGVNAWTCPQSKVSIQpgqhcpGLGLVEDDCSGNPctckpqafigwssetclqNG RCNIfanfilndvnsgttcstdlqQGNTIITTDVCVNYDLYGITGQGILIEVNATYynsWQNLLYDSSGNLYGFRDYLSNrTFLIRSCYSGRVSAVFHAN SSEPALMFRNLKCSHV------FNNTILRQIQLVN--YFDSYLGCVVNaYNNTASAVSTCDLTVGSGYCVDYvtalrsRRSFTTGYRFTNFEPFAANLVN DSiepvgGLYEIQIPSEFTIGNLEEFIQTRSPKVTIDCATFVCGDYAACRQQLAEYGSFCENINAILTEVNELLDttqlQVANSLMNGVTLSTKIKDGIN FNvDDINFSPVLgclgsecNRASTRSAIEDLLFDKVKLSDVGFVQAYNNCTGgaeiRDLICVQSYNGIKVLPPLLSENQISGYTLAATAASLFPPWTAAA gVPFYLNVQYRINGLGVTMDVLSQNQKLIASAFNNALDAIQEGFDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISASLQEILSRLDALEAKAQID RLINGRLTALNAYVSQQLSDSTLVKFSAAQAIEKVNECVKSQSSRINFCGNGNHIISLVQNAPYGLYFIHFSYVPTKYVTAKVSPGLCIAGDI-GISPKS GYFI-NVNNSWMFTGSSYYYPEPITQNNVVVMStcavnytkaPDLMLNTSTPNLP---- >UniRef50_P59594(24-1123:1255) Spike protein S2 n=151 Tax=Betacoronavirus RepID=SPIKE_CVHSA E=0 s/c=0.95 id=31% cov=95% ----DVQaPNYTQHT-------SSMRGVYYP-DEIFRSDTLYLTQdlFLPFYSN------VTGFHTINHTF----GNPVIPFKDGIYFAATEKSNVVRGW VFGSTMNNKSQ--SVIIINNSTNVVIRACNFELCDNPFFAVSKPMGTQTHTMIFD----NAFNCTFEYISDAFSLDVSEKSGNFK-----------HLRE FVFKNKDGFLY--VYKGYQPIDVVRDLPSGF--NTLKPIFKLPLGINITNFRAILTAFSPAQdiwGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQ NPLAELKCSVKSFEIDKGIYQTSNFRVVPSGdVVRFPNITNLCPFgEVFNATKFPSVYAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFS NVYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFMGCVLaWNTRNIDATSTGNY--NYKYRYLRHGKLRPFERDISNVPFSPDG--KPCTPP---ALN CY-WPLNDYGFYTTTGIGYQPYR------VVVLSFELLNAPATVCGPKLSTDLIKNQCVNFNFNGLTGTGVLTPSSkrFQPFQQFGRDVSDFTDSVRDpK TSEILDISPCSFGGVSVITPgtNASSEVAVLYQDVNCTDVSTAIHADQLTPAWRIYSTGNNVFQTQAGCLIGAEHV-DTSYECDIPIGAGICASYHTvsl lRSTSQKSIVAYTMSLGAdSSIAYSNNTIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQYGSFCTQLNRALSGIAAEQDRNTREVFA QVKQMYKTPTLKYFGG-FNFSQIlpdPLKPTKRSFIEDLLFNKVTLADAGFMKQYGECLGdinaRDLICAQKFNGLTVLPPLLTDDMIAAYTAALVSGTA TAGWTfgagaALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILS RLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPAIC HEG--KAYFPREGVFVFNGT-SWFITQRNFFSPQIITTDNTFVSgNCDVVIGIINNTVYDPL- >UniRef50_P05135(208-1017:1163) Spike protein S2 n=1237 Tax=Avian coronavirus RepID=SPIKE_IBV6 E=1e-180 s/c=0.79 id=33% cov=48% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------LDRCVEYNIYGRVGQGFITNVTnyAINYNYLadggmaILDTSGAIDIFVVQGEyg lNYYKVNPCEDVNQQFV----------------VSGGKLVGILTSRNETGSQPLENQFYIKIINGTRRSRRSITGNVTNCPYVTYGKFCIKPDGSIST-- -IVPKELEHFVAPLLNVTENVLIPDSFNLTVTDEYIQTRMDKVQINCLQYVCGNSLECRKLFQQYGPVCDNILSVVNSVGQKEDMELLYFYSSTKPSgFN TPVLSNVStGEFNISLLLTPPssaSGRSFIEDLLFTSVESVGLPTDDAYKKCTAgplgflKDLACAREYNGLLVLPPIITAEMQTLYTSSLVASMAFGGI TsAGAIPFATQLQARINHLGITQSLLFKNQEKIAASFNKAIGHMQEGFRSTSLALQQIQDVVNKQSSILTETMASLNKNFGAISSVLQDIYQQLDSIQAD AQVDRIITGRLSSLSVLASAKQAEYYRVSQQRELATQKINECVKSQSIRYSFCGNGRHVLTIPQNAPNGIVFIHFTYTPESFVNVTAIVGFCVnpaNASQ YAIVPANGRGIFiQVNGSYYITARDMYMPRDIT------------------------- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * C 1 * 0 * * * * * * * * * * * * * * * * * * 1 0 * * * * * * 1321 0 0 I 2 * * * * * * * 987 * 1013 * * * * * * * * * * 2 0 * * * * * * 1321 0 0 V 3 * * 1013 * * * * * * * * * * * * * * 987 * * 3 0 * * * * * * 1321 0 0 V 4 * * * * * * * * * * * * * * * 1013 * 987 * * 4 0 * * * * * * 1321 0 0 D 5 * * 545 * * * * * * * * * * 1669 * * * * * * 5 0 * * * * * * 1806 0 0 M 6 * * * * * * * * * * 1626 * * * * * * 565 * * 6 0 * * * * * * 1806 0 0 Q 7 * * * * * * * * * * * * * 0 * * * * * * 7 648 1467 * 0 * * * 1806 1000 0 P 8 * * * * * * * * * * * * 0 * * * * * * * 8 0 * * * * * * 1806 0 0 S 9 * * 1669 * * * * * * * * 1467 * * * 1626 * * * * 9 0 * * * * * * 1806 0 0 Y 10 * * * * * * * * * * * * * * * * * * * 0 10 0 * * * * * * 1806 0 0 F 11 * * * * 648 * * * * * * * * * * * 1467 * * * 11 0 * * * * * * 1806 0 0 Q 12 * * * 1669 * * * * * * * * * 545 * * * * * * 12 0 * * * * * * 1806 0 0 R 13 * * * * * * 1467 * * * * * * * 1626 1669 * * * * 13 545 1669 * 1585 585 * * 1806 1000 0 D 14 * * 1626 * * * * * * * * * * * * * 565 * * * 14 648 * 1467 * * * * 1806 0 0 W 15 * * * * * * * * * * * * * * * * * * 0 * 15 0 * * * * * 0 1321 0 1000 P 16 * * * * * * * * * * * * 0 * * * * * * * 16 0 * * * * * 0 1321 0 1000 R 17 * * * * * * * * * * 1013 * * * 987 * * * * * 17 0 * * * * * 0 1321 0 1000 P 18 * * * * * * * * * * * * 0 * * * * * * * 18 0 * * * * * 0 1321 0 1000 I 19 * * * * * * * 948 * * * * * * * * * 1053 * * 19 0 * * * * * 0 1979 0 1000 N 20 * * 429 * * * * * * * * 1959 * * * * * * * * 20 0 * * * * * 0 1979 0 1000 M 21 * * * * * * * * * * 1959 * * * * * 1938 1053 * * 21 0 * * * * 0 * 1979 0 1000 S 22 * * * * * * * * * * * * * * * 302 2406 * * * 22 0 * * * * * * 2341 0 0 A 23 2343 * * * * * * * 1388 * * 2406 * * * 2107 * * * * 23 0 * * * * * * 2341 0 0 A 24 1344 * * * * 1420 * * * * 2107 * * * * * * * * * 24 0 * * * * * * 2341 0 0 D 25 * * 2343 2344 * * * * * 1420 * * * * 2107 * * * * * 25 0 * * * * * * 2341 0 0 G 26 * * * * * 0 * * * * * * * * * * * * * * 26 0 * * * * * * 2341 0 0 I 27 * * * * * * * 2343 * * * * * * * * 1420 1221 * * 27 0 * * * * * * 2341 0 0 I 28 * * * * 2406 * * 1344 * * * * * * * * * * * 1261 28 0 * * * * * * 2341 0 0 Y 29 * * * * * * * * * * * * * * * * * * * 0 29 0 * * * * * * 2341 0 0 P 30 * * * * * * * * * * * * 675 * * * * 1420 * * 30 381 * 2107 * * * * 2341 0 0 V 31 * * * * * * * * * 1053 * 1938 * * * * * 1959 * * 31 0 * * * * 0 * 1979 0 1000 G 32 * * 723 * * 1344 * * * * * * * * * * * * * * 32 0 * * * * * * 2341 0 0 R 33 * * * 2107 * * * * 2344 * * * * * 809 * * * * * 33 0 * * * * * * 2341 0 0 T 34 * * * * * * * 2107 * * * * * * * 2344 2343 1420 * * 34 0 * * * * * * 2341 0 0 Y 35 * * * * 2107 * * * * * * * * * * * * * * 381 35 0 * * * * * * 2341 0 0 A 36 2343 * * * * * * * * 1420 * * * * 2107 2344 * * * * 36 0 * * * * * * 2341 0 0 N 37 * * * * * * * * * * * 381 * * * 2107 * * * * 37 0 * * * * * * 2341 0 0 I 38 2433 * 2107 * * * * 1344 * * * * * * * * 2406 * * * 38 0 * * * * * * 2341 0 0 T 39 * * * * * * * * * * * * * * * * 0 * * * 39 0 * * * * * * 2341 0 0 I 40 * * * * * * * 2343 * 317 * * * * * * * * * * 40 0 * * * * * * 2341 0 0 M 41 * * * * * * * * * 1420 2343 * * * * * 2344 * * 2107 41 0 * * * * * * 2341 0 0 L 42 * * * * * * * * * 316 * * * * * * * * * 2344 42 0 * * * * * * 2341 0 0 S 43 * * * * * * * * * * * 2406 * * * 2343 703 * * * 43 0 * * * * * * 2341 0 0 G 44 * * * * * 381 * * * * * * * 2107 * * * * * * 44 381 2107 * 1000 1000 * * 2341 1000 0 L 45 * * * * 2107 * * * * 1344 * * * * * * * * * 1420 45 0 * * * * * * 2341 0 0 F 46 * * * * 2343 * * * * 2107 * * * * * * * * * 809 46 0 * * * * * * 2341 0 0 P 47 * * * * * * * * * * * * 0 * * * * * * * 47 302 2406 * 2807 222 * * 2341 1000 0 H 48 * * * * 2107 * 2343 * 2344 * * 2406 * * * * * 2433 * * 48 0 * * * * * * 2341 0 0 Q 49 2344 * 2433 * * * * * * * 2406 * * 2343 * * * * * 2107 49 0 * * * * * * 2341 0 0 A 50 1374 * * * * 2433 * * * * * 2344 * * * 2107 * * * * 50 0 * * * * * * 2341 0 0 D 51 * * 1344 * * * * * * 2406 * 2107 * * * 2433 * * * * 51 381 * 2107 * * * * 2341 0 0 K 52 * * * * * * * * 1001 1938 * 2064 * * * * * * * * 52 0 * * * * * 0 1979 0 1000 G 53 * * * * * 394 * * * * * * * * * * * * * 2064 53 0 * * * * * 0 1979 0 1000 K 54 * * * * * * * * 948 * * * * * 2064 * 2043 * * * 54 0 * * * * * 0 1979 0 1000 Q 55 * * * * * * * * * * * 2064 * 948 2043 * * * * * 55 0 * * * * * 0 1979 0 1000 Y 56 * * * * * * * * * 1053 * * * * * * * * * 948 56 0 * * * * * 0 1979 0 1000 I 57 2064 * * * * * * 1959 * 989 * * * * * * * * * * 57 0 * * * * 0 * 1979 0 1000 Y 58 * * * * 2344 * * * * 2433 * * * * * 2406 * 2107 * 2343 58 0 * * * * * * 2341 0 0 S 59 * * * * * * * * * * * * * * * 1344 723 * * * 59 0 * * * * * * 2341 0 0 M 60 * * 2344 * * 1261 * * * 2406 2343 * * * * * * * * * 60 0 * * * * * * 2341 0 0 Y 61 * * * * 2107 2344 * * * * * * * * * * 2433 * 2406 2343 61 0 * * * * * * 2341 0 0 H 62 * * * * 2406 * 675 * * * * 2433 * * * * * * * * 62 703 2344 2406 2000 415 * * 2341 1000 0 M 63 * * * * * * * * * * 2092 * * * 2106 * 908 * * * 63 0 * * * * * 0 2175 0 1000 V 64 * * * * * * * 1887 * 1014 * * * * * * * 2092 * * 64 440 1928 * 2322 322 0 * 2175 1000 1000 N 65 * * * * * * * * 1420 * * 675 * * * * * * * * 65 0 * * * * * * 2341 0 0 D 66 * * 2343 * * * 2107 * * * * 2344 1420 * * * * * * * 66 0 * * * * * * 2341 0 0 P 67 * * * * * * * * * 2344 * * 809 * * * 2107 * * * 67 0 * * * * * * 2341 0 0 F 68 * * * * 0 * * * * * * * * * * * * * * * 68 381 * 2107 * * * * 2341 0 0 I 69 * * * * * * * 1959 * 1053 * * * * * * * 1938 * * 69 0 * * * * * 0 1979 0 1000 S 70 * * * * * * * * * * * * * * * 0 * * * * 70 401 * 2043 * * * 0 1979 0 1000 N 71 * * * 1479 * * * * * * * 641 * * * * * * * * 71 641 * 1479 * * * 0 1780 0 1552 Y 72 * * * * * * * * * * * * * * * * * * * 0 72 0 * * * * 1376 702 1321 0 1777 S 73 * * * * * 1467 * * * * * * * * * 648 * * * * 73 0 * * * * * 0 1806 0 1281 Y 74 * * * * * * * * * * * 1467 * * * 1669 * * * 1626 74 0 * * * * * 0 1806 0 1281 Y 75 * * * * * * * * * * * * 1467 1669 * * * * * 1626 75 0 * * * * * 0 1806 0 1281 T 76 * * * * * * * * * * * * * * * * 1626 565 * * 76 0 * * * * * 0 1806 0 1281 E 77 * * * 648 * * * 1467 * * * * * * * * * * * * 77 0 * * * * 992 1008 1806 0 1281 P 78 * * * * * * * * * * * * 379 * * 2115 * * * * 78 0 * * * * 0 * 2185 0 1000 F 79 * * * * 0 * * * * * * * * * * * * * * * 79 0 * * * * * * 2341 0 0 D 80 * * 1344 * * * * * 2107 * * 1420 * * * * * * * * 80 0 * * * * * * 2341 0 0 N 81 * * 317 * * * * * * * * 2343 * * * * * * * * 81 0 * * * * * * 2341 0 0 G 82 * * * * * 0 * * * * * * * * * * * * * * 82 0 * * * * * * 2341 0 0 F 83 * * * * 1344 * * 723 * * * * * * * * * * * * 83 0 * * * * * * 2341 0 0 V 84 * * * * 1420 * * * * * * * * * * * * 1344 * 2107 84 0 * * * * * * 2341 0 0 V 85 1420 * * * 2107 * * * * * * * * * * * * 1344 * * 85 0 * * * * * * 2341 0 0 R 86 2107 * * * * * * * 1420 * * * * * 1344 * * * * * 86 0 * * * * * * 2341 0 0 I 87 2107 * * * * * * 1344 * * * * * * * * * 1420 * * 87 675 * 1420 * * * * 2341 0 0 G 88 * * * * * 648 * * * * * * * * * * 1467 * * * 88 0 * * * * 992 1008 1806 0 1281 A 89 1105 * * 1892 * * * * 1913 * * * * * * * * * * * 89 0 * * * * * 0 2185 0 1000 N 90 2115 * * * * * * * 1892 * * 1001 * * * * * * * * 90 0 * * * * 0 * 2185 0 1000 S 91 2344 * * * * * * * * * * * * 2433 * 694 * * * * 91 0 * * * * * * 2341 0 0 N 92 * * * * * * * * * * * 302 * * 2406 * * * * * 92 0 * * * * * * 2341 0 0 I 93 * * * * 2406 * * 2343 2344 2433 * * * * * * * 2107 * * 93 0 * * * * * * 2341 0 0 T 94 * * * * * * * * 2433 * * * * * * 2406 1344 2107 * * 94 0 * * * * * * 2341 0 0 G 95 * * * * * 1344 * * 2406 * * * * * 2107 * 2433 * * * 95 0 * * * * * * 2341 0 0 S 96 * * 2406 * * 2107 * * * * * 2433 * * * 2343 2344 * * * 96 0 * * * * * * 2341 0 0 S 97 * * * * * 2406 * * * * * * * * * 2343 1388 * 2107 * 97 0 * * * * * * 2341 0 0 V 98 * * * * * * * * * * * * 2433 * * * * 295 * * 98 0 * * * * * * 2341 0 0 V 99 * * * * 2107 * * 1375 * * * * * * * * 2433 2343 * * 99 0 * * * * * * 2341 0 0 G 100 * * * * * 703 * * * * * * * * * 2344 * * * 2406 100 316 2344 * 0 * * * 2341 1000 0 S 101 2433 * * * * * * * * * * * * * * 295 * * * * 101 0 * * * * * * 2341 0 0 A 102 2343 * * 2406 * * * * * * * * * * * * 703 * * * 102 302 * 2406 * * * * 2341 0 0 N 103 * * * * 2106 * * * * * 1887 2092 * * * 1928 * * * * 103 440 * 1928 * * * 0 2175 0 1000 A 104 1626 * * * * * * * 1669 * * 1467 * * * * * * * * 104 0 * * * * * 0 1806 0 1281 T 105 * * * * * * * * * * * 1467 1669 * * * 1626 * * * 105 0 * * * * * 0 1806 0 1281 V 106 * * * * * * * 1669 1467 * * * * * * * * 1626 * * 106 0 * * * * * 0 1806 0 1281 K 107 * * * * * * * * 648 * * * * * * 1467 * * * * 107 0 * * * * * 0 1806 0 1281 K 108 * * * * * * * * 648 * * * * 1467 * * * * * * 108 648 * 1467 * * 1008 992 1806 0 1281 I 109 * * * * * * * 641 * * * * * * * * * * * 1479 109 0 * * * * 995 1005 1780 0 1552 Y 110 * * * * 1053 * * * * * * * * * * * * * * 948 110 0 * * * * 0 * 1979 0 1000 P 111 * * * * * * * * * * * * 381 * * 2107 * * * * 111 0 * * * * * * 2341 0 0 A 112 779 * * * * * * * * * * * * * * * 2433 2107 * * 112 0 * * * * * * 2341 0 0 L 113 * * * * 2344 * * 723 * 2343 * * * * * * * * * * 113 0 * * * * * * 2341 0 0 M 114 * * * * * * * 2107 * 2344 2343 * * * * * 2406 2433 * * 114 0 * * * * * * 2341 0 0 L 115 * * * * * * * 723 * 1344 * * * * * * * * * * 115 0 * * * * * * 2341 0 0 G 116 * * * * * 381 * * * * * 2107 * * * * * * * * 116 0 * * * * * * 2341 0 0 S 117 * * * * * * 2344 * * * * 2107 * * * 809 * * * * 117 0 * * * * * * 2341 0 0 V 118 * * * * * * * * * 2433 * * * * * 1221 2406 2343 * * 118 302 * 2406 * * * * 2341 0 0 V 119 * * * * 1928 * * * * * * * * * * * 1887 1099 * * 119 0 * * * * * 0 2175 0 1000 G 120 * * * * * 352 * * * * * 2209 * * * * * * * * 120 0 * * * * * 0 2537 0 1000 K 121 2210 * * * * * * * 2477 * * 1366 * * * * * 2209 * * 121 334 * 2276 * * * 0 2537 0 1000 F 122 * * * * 2102 * * * * * * * * * * * * 1876 * 1016 122 375 2127 * 0 * * 0 2240 1000 1281 P 123 * * * * * * * 1876 * * * * 459 * * * * * * * 123 0 * * * * * 0 2240 0 1281 S 124 * * * * * * * * * * * * * * 1876 459 * * * * 124 0 * * * * * 0 2240 0 1281 N 125 1876 * * * * * * * * * * 1114 * * * * 1913 * * * 125 0 * * * * * 0 2240 0 1281 K 126 * 1876 * * * * * * 2102 * * 1913 * * 2127 * * * * * 126 0 * * * * * 0 2240 0 1281 T 127 * * * * * * * * 1913 * * 1876 * * * * 1114 * * * 127 0 * * * * * 0 2240 0 1281 G 128 1913 * * * 1876 1114 * * * * * * * * * * * * * * 128 0 * * * * * 0 2240 0 1281 R 129 * * * 1876 * * * * 1913 * * * * * 1114 * * * * * 129 0 * * * * 992 1008 2240 0 1281 Y 130 * * * * 2249 * * * * 2214 * * * * * * * * 2219 1477 130 0 * * * * * 0 2551 0 1000 F 131 * 2214 * * 1342 * * * * 2477 * * * * * * * 2249 * * 131 0 * * * * * 0 2551 0 1000 N 132 * 2219 2214 * * * * * * * * 812 * * * * * * * * 132 0 * * * * * 0 2551 0 1000 H 133 * * * * * * 1477 * * * * 2214 2219 * * * 2249 * * * 133 0 * * * * * 0 2551 0 1000 T 134 * * * * * * * * * * * * 2214 * * 2249 801 * * * 134 0 * * * * * 0 2551 0 1000 L 135 * * * * 2214 * * * * 1477 * 2219 * * * * * * * 2249 135 0 * * * * * 0 2551 0 1000 V 136 * * * * 2214 * * * * * * * * * * 2249 * 801 * * 136 0 * * * * * 0 2551 0 1000 I 137 2214 * * * * 2219 * 812 * * * * * * * * * * * * 137 0 * * * * * 0 2551 0 1000 L 138 * * * * * * * * * 1477 * * * * 2219 * * 1231 * * 138 0 * * * * * 0 2551 0 1000 P 139 * * * * * * * * * * * * 801 * * 2214 * 2249 * * 139 0 * * * * * 0 2551 0 1000 E 140 * * 2477 1358 * * * * 2214 * * * * * * * * 2219 * * 140 0 * * * * * 0 2551 0 1000 K 141 * * * * * 1342 * * 2476 * * * 1231 * * * * * * * 141 0 * * * * * 0 2551 0 1000 C 142 * 1477 * * * * 2249 * * * 2214 * * * * * 2219 * * * 142 0 * * * * * 0 2551 0 1000 G 143 * * * * * 341 * * * * * * * * * * 2249 * * * 143 0 * * * * * 0 2551 0 1000 T 144 * * * * * * * * * * * * * * * 2249 799 2219 * * 144 0 * * * * * 0 2551 0 1000 Q 145 * * * * * 2219 * 2477 * 2249 * * * 1339 * * * * * * 145 0 * * * * * 0 2551 0 1000 I 146 * * * * * * * 725 * 2477 * * * * * * 2214 * * * 146 0 * * * * 0 * 2551 0 1000 T 147 * * * * * 2373 1528 * * * * 2690 * * * * 1713 * * * 147 0 * * * * * * 2681 0 0 A 148 1684 * * * * 2690 * * * * * * * * * 2729 2397 2373 * * 148 243 * 2690 * * * * 2681 0 0 L 149 * * * * 2463 * * * * 2477 2209 * * * * * * * * 1243 149 0 * * * * * 0 2537 0 1000 Y 150 2210 * * * * * * 2209 * * * * * * * * 2276 * * 1470 150 0 * * * * * 0 2537 0 1000 C 151 * 1470 * * 2209 * * * * * * * * 2210 * * * 2276 * * 151 0 * * * * 0 * 2537 0 1000 V 152 * * 2397 * * * * * * * * 2690 * * * * 2373 1114 * * 152 304 * 2397 * * * * 2681 0 0 L 153 2103 * * * * * * * * 382 * * * * * * * * * * 153 0 * * * * * 0 2364 0 1000 Q 154 * * * 2426 * * 2335 * * * * * * 700 * * * * * * 154 0 * * * * * 0 2364 0 1000 P 155 2103 * * * * 2389 * * * * * * 795 * * * * * * * 155 0 * * * * * 0 2364 0 1000 K 156 * * * * * * * * 2381 2389 * * * * 2335 2103 * * * 2426 156 0 * * * * 0 * 2364 0 1000 N 157 * * * * * * * * * 2690 * 1015 * * * * 2671 * * 2373 157 0 * * * * * * 2681 0 0 Q 158 2397 * * 2373 * * * * * * * 2729 * 1101 * * * * * * 158 0 * * * * * * 2681 0 0 T 159 * * * * 2397 * * 1709 * * * * * 2671 * * 1526 * * * 159 0 * * * * * * 2681 0 0 N 160 * * * * * 2373 * 2729 * * * 997 * * * 2690 * * * * 160 0 * * * * * * 2681 0 0 C 161 * 997 * * * 2373 * * * * 2729 * * * * * * 2690 * * 161 0 * * * * * * 2681 0 0 T 162 1700 2690 * * * * * * * * * * * * * 2373 1539 * * * 162 0 * * * * * * 2681 0 0 G 163 * * * * 2397 988 * * * * * * * 2690 * 2729 * * * * 163 0 * * * * * * 2681 0 0 H 164 2373 * * 1528 * * 2696 * * * * * * * * * * 2729 * 2690 164 0 * * * * * * 2681 0 0 T 165 * 2729 * * * 2373 * * * * * * * * * * 1101 * * 2397 165 0 * * * * * * 2681 0 0 T 166 * * * * * 2373 * 2397 * * 2690 2671 * * * * 1713 * * * 166 243 2690 * 1000 1000 * * 2681 1000 0 Y 167 * * * * 2671 * * * * * * * * * * 2397 * * * 615 167 0 * * * * * * 2681 0 0 T 168 * * 2397 * * * * * 2671 * * * 2690 * * * 1005 * * * 168 236 2729 * 2000 415 * * 2681 1000 0 S 169 2397 * * * 2373 * 2690 * * * * * 2729 * * 1684 * * * * 169 0 * * * * * * 2681 0 0 Y 170 * * * * 2397 * * * * 2671 * * * * * 2373 2690 * * 1713 170 0 * * * * * * 2681 0 0 V 171 * * * * * * * 2690 * * * * * * * 1528 2729 1526 * * 171 0 * * * * * * 2681 0 0 L 172 * 2690 * * * * * * * 997 * * 2729 * * 2373 * * * * 172 0 * * * * * * 2681 0 0 V 173 * 2729 2397 * * * 2690 * * * * * 2373 * * * * 2696 2671 * 173 0 * * * * * * 2681 0 0 E 174 * * 2671 2696 * * * * 1540 * * * 2690 * * * * 2397 * * 174 246 2671 * 3459 138 * * 2681 1000 0 N 175 * * * * * * 2373 * * * * 1101 2729 * * 2397 * * * * 175 0 * * * * * * 2681 0 0 K 176 * * * 2397 * * * * 2696 2690 * 2729 * 2671 * * * 2373 * * 176 0 * * * * * * 2681 0 0 T 177 * * * 2671 * 2690 * * 2397 * * * * * * * 1005 * * * 177 0 * * * * * * 2681 0 0 N 178 2671 * * * * * * * * * * 615 * * * 2397 * * * * 178 243 * 2690 * * * * 2681 0 0 L 179 * * * * * 1242 * * * 1337 * * * * * * 2463 * * * 179 0 * * * * * 0 2537 0 1000 K 180 * * * * * * * * 2477 2463 * 1242 * * * * 2210 * * * 180 0 * * * * 0 * 2537 0 1000 Q 181 * * * * 2397 2671 * * * * * * * 1693 2729 * * * 2373 * 181 0 * * * * * * 2681 0 0 S 182 2671 * * * * * * * 2397 * * * * * 2690 1526 * 2729 * * 182 304 * 2397 * * * * 2681 0 0 L 183 * * * * 2335 * * 1408 * 1235 * * * * * * * * * * 183 0 * * * * * 0 2364 0 1000 Q 184 * * * 2389 * 2426 * * 2335 * * * * 2381 * * * * 2103 * 184 0 * * * * * 0 2364 0 1000 T 185 * * * * 2426 * * * * 2389 * * * * * * 2381 1214 * * 185 0 * * * * * 0 2364 0 1000 W 186 * * * * * * 2103 * * * * * * * * * * * 814 2335 186 0 * * * * * 0 2364 0 1000 F 187 * * * * 1357 * 1408 * * * * * * * 2103 * * * * * 187 1357 714 * 2143 370 * 0 2364 1810 1000 D 188 * * 382 * * * * * * * * * * * * * 2103 * * * 188 0 * * * * * 0 2364 0 1000 L 189 * * * * * * * * * 1357 * * * * * * * 714 * * 189 0 * * * * * 0 2364 0 1000 K 190 * * * * * * * 2335 1403 * * * * * 2103 * * 2389 * * 190 0 * * * * * 0 2364 0 1000 D 191 * * 2381 * * * * * * 2103 * 2335 2426 * * 2389 * * * * 191 297 2426 * 1000 1000 * 0 2364 1000 1000 C 192 * 0 * * * * * * * * * * * * * * * * * * 192 0 * * * * * 0 2364 0 1000 L 193 * * * * * * * * * 814 * * * * 2103 * 2335 * * * 193 0 * * * * 0 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