HHsearch 1.5 NAME c9iqyB_ FAM FILE c9iqyB_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9iqyB_.a3m DATE Sat May 31 10:32:18 2025 LENG 90 match states, 90 columns in multiple alignment FILT 43 out of 45 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 3.9 EVD 0.4531 1.4668 SEQ >ss_pred CCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCEEEEECCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHCC >ss_conf 931244532089999999642000011233220245632131775406310467378553589999548953576641323799985329 >Consensus PLxLAAkxgxxemFxxILxxexxxxxxxxlxrrxxxWxyGpvtxsxYdLxxiDTixxxxSaLeiivxxxxxxxxlxmlxxxpixxLLxxK >c9iqyB_ PLMMAAKTGKIGIFQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYDLSSLDTCGEEASVLEILVYNSKIENRHEMLAVEPINELLRDK >UniRef50_UPI000069D9E0(168-245:553) Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L). n=1 Tax=Xenopus (Silurana) tropicalis RepID=UPI000069D9E0 E=8e-21 s/c=1.29 id=32% cov=88% PFKLAAQQGDVQMFEYFIKK-----------RRHTILSFGPLGSTLYDLTGIDSWDDRLSVIDIICTSNNNAARN-LLEITPLKELLHYK >UniRef50_Q018G0(94-168:466) Vanilloid receptor-related osmotically activated cha (ISS) n=1 Tax=Ostreococcus tauri RepID=Q018G0_OSTTA E=2e-05 s/c=0.67 id=33% cov=84% PLLFAARSGFRDMFEFLIERSC-----------VTEWSYGPVTCKRMPLYEVDTSNGSKSALKEIVDND----HEDLLELPLIRELIQRK >UniRef50_C3YKR4(201-288:581) Putative uncharacterized protein n=1 Tax=Branchiostoma floridae RepID=C3YKR4_BRAFL E=9e-18 s/c=1.04 id=34% cov=91% PVKLAADSGNLEMFQVLLD---------PSRKQHVLWKYGPVSECLYDLTDIDSTqrGACNGLLEIVVYSNvrrfyTNIKAAKMVQTTPIKQLLNKK >UniRef50_O17469(300-382:937) Osmotic avoidance abnormal protein 9, confirmed by transcript evidence n=9 Tax=Chromadorea RepID=O17469_CAEEL E=2e-06 s/c=0.64 id=32% cov=88% PLTLATKLGRKQIFEEMLEI-----------MKVEFWRFSDMTCSAYPLNTLDTIqpdgsTNYDSALMTVINGS-TPEHLDMIGSEVIQRLLADK >UniRef50_UPI0000E46E0D(255-336:733) PREDICTED: similar to GA18240-PA n=1 Tax=Strongylocentrotus purpuratus RepID=UPI0000E46E0D E=2e-06 s/c=0.65 id=29% cov=87% -LQLSFQLGRNELFSALLELS-----------SETQWTYGKIAYVAYPLSILDSIDsegcvNSSSALSVIVQYDTI-NHLKMLEGQVIDELLHVK >UniRef50_A7SGQ7(299-380:736) Predicted protein n=1 Tax=Nematostella vectensis RepID=A7SGQ7_NEMVE E=3e-18 s/c=1.13 id=29% cov=87% PLTLAAKLARNEMFHHILTKS-----------REVFWEYGNVTAAAFPLWELDTIGDQGQVIERsainIIIHEDSHEHLELLDGIVLNILTE-- >UniRef50_UPI0000584268(312-393:911) PREDICTED: similar to conserved hypothetical protein n=1 Tax=Strongylocentrotus purpuratus RepID=UPI0000584268 E=2e-15 s/c=1.02 id=37% cov=87% PLCLAAELADIEFFESIIHLE-----------RQVSWKYGDVTCALYPLYNLDSIGvdgsvNEKSALFTIVNQSDIDHLGLM--KGLMTKLLHEK >UniRef50_A6YBE8(127-214:277) Trpv (Fragment) n=1 Tax=Platynereis dumerilii RepID=A6YBE8_PLADU E=2e-05 s/c=0.57 id=25% cov=92% PVTWAAKFKHKEMLDFILNIEGVY--------RQTVWQFGHSSFLHYDMKDIDSVitsiqkPGKPSVVELLTYSPVRGNTLNCISIPVIKELVAYK >UniRef50_C1EBU4(254-333:1187) Transient receptor potential Ca2+ channel family n=1 Tax=Micromonas sp. RCC299 RepID=C1EBU4_9CHLO E=7e-10 s/c=0.81 id=33% cov=84% PFLIAARDGNAHAFNRVLRRKFAAV-----------WRFGPVTSYNLNLTGIDTVGARASdrpenAVDVLVRS----HRIELLSHPVLVAVLDLK # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * P 1 * * * * * * * * * * * * 0 * * * * * * * 1 0 * * * * * * 3962 0 0 L 2 * * * * 3065 * * 4506 * 505 5191 * * * * * * 3261 * * 2 0 * * * * * * 3994 0 0 M 3 3765 5208 * * * * * * 2086 3919 4438 * * 3485 * * 1201 5191 * * 3 0 * * * * * * 3994 0 0 M 4 * * * * 5061 * * 4791 * 337 3490 * * * * * * * 4234 * 4 0 * * * * * * 3994 0 0 A 5 73 * * * * * * * * * * * * * * 4344 * * * * 5 0 * * * * * * 3994 0 0 A 6 379 4426 * * 5150 5225 * * * * * * * * * 4696 3460 * * * 6 0 * * * * * * 3994 0 0 K 7 * * 4290 5208 3756 4371 3832 * 978 * * * * 3590 3163 * * 5225 * * 7 0 * * * * * * 3994 0 0 T 8 * * 4017 2845 4234 * * 5283 5474 1215 4464 * * 5012 * 3624 3191 * * * 8 0 * * * * * * 3994 0 0 G 9 2371 * * * * 501 * * 4234 * * * * * * 4419 * * * * 9 0 * * * * * * 3994 0 0 K 10 * * 4107 * 5061 * 4234 * 1337 * * 2114 * * 2265 * * * * 5387 10 33 5482 * 4585 61 * * 3994 1000 0 I 11 3554 * * * * * * 2591 2090 2686 * 3617 4251 4334 5061 5607 5225 3354 * * 11 0 * * * * * * 3994 0 0 G 12 * * 3122 1283 * 3064 3582 * 4600 * * * * 2628 * * 5891 4285 * * 12 0 * * * * * * 4086 0 0 I 13 4814 * * * 5270 * * 2861 * 2511 955 * * * * 5403 * 3540 * * 13 0 * * * * * * 4086 0 0 F 14 * * * * 292 * * * * 3106 5373 * * * * * * 5885 * 5256 14 0 * * * * * * 4086 0 0 Q 15 5673 * 3141 2335 4040 * 5106 * 3214 * * 3687 * 2466 3053 3440 * * * * 15 0 * * * * * * 4086 0 0 H 16 5172 * * 4077 3640 5207 1266 * 4006 5256 * * * 5912 4066 5270 5309 4365 * 2993 16 0 * * * * * * 4086 0 0 I 17 * * * * 4170 * * 682 * 2279 3978 * * * * * * 4271 * * 17 0 * * * * * * 4086 0 0 I 18 * * * * * * * 2539 * 714 3027 * * * * * * 3389 * * 18 0 * * * * * * 4086 0 0 R 19 * * 4365 1781 * 5306 3777 * 3024 * * 3180 * 2716 3707 3813 5106 * * * 19 112 * 3743 * * * * 4086 0 0 R 20 * * * 5276 * * * 2692 2724 2078 * * * * 1271 * 5888 * * * 20 261 * 2597 * * * 0 3938 0 1604 E 21 * * * 545 * 4988 * * 4467 * * * * 4779 * 2575 4901 * * * 21 470 * 1848 * * * 0 3708 0 2853 V 22 3061 3581 * * 1766 3168 * 2824 * 4807 * * * * 4722 2794 * 4949 * * 22 132 * 3520 * * * 0 3441 0 3323 T 23 3859 * 4776 4706 * * * * 1966 * 4711 * 4061 2035 4530 4621 3574 3470 * * 23 208 * 2900 * * * 0 3341 0 3407 D 24 3877 * 2064 1834 * * * 3856 3173 * * * 4395 4321 * 4471 * * * 3479 24 624 * 1511 * * * 0 3259 0 3461 E 25 * * * 2239 * * * * 3611 * * 2661 2921 * 3898 3998 * 1803 * * 25 487 * 1803 * * 3021 190 2595 0 3767 D 26 * * 1564 2148 * 2682 * * * 3719 * * * * 2291 * * * * * 26 197 2973 * 0 * * 0 2183 1000 3804 T 27 * 2751 * * * * * * * 2459 2099 * * * * * 1822 3693 * 3719 27 0 * * * * * 0 2183 0 3804 R 28 * * * * * * 2973 * 2850 * * * * * 621 3581 * * * * 28 0 * * * * 3663 119 2183 0 3804 H 29 * * * * * * 542 * * * * * 2129 * * 3562 * * * * 29 0 * * * * * 0 2409 0 3864 L 30 * * * * * * * * * 210 * * * * * 2882 * * * * 30 0 * * * * 4352 72 2409 0 3864 S 31 * 2367 * * * * * * * * * * * * 3041 547 * * * * 31 0 * * * * 2126 375 2594 0 3992 R 32 * * 3977 * * * * * 2348 * 3752 * * * 587 * * * * * 32 0 * * * * 978 1022 3194 0 3756 K 33 * * * * * * * * 1284 * 4791 * * 4156 1118 4774 * * * * 33 0 * * * * 2381 308 3761 0 3082 F 34 * * 4025 2512 1757 * 3062 5338 * 5088 * 4133 * 3367 * * 4938 3223 * * 34 0 * * * * 3066 183 3837 0 2829 K 35 * * * 4819 * * * 2133 4338 * * * * * * * 1228 1942 * * 35 0 * * * * 753 1298 3872 0 2772 D 36 5231 * 3798 2032 2652 * * 4289 * 4336 * 5290 * 3593 * 3734 * 4142 * 2671 36 0 * * * * 0 * 3997 0 1832 W 37 * * * * * * * * * 5046 * * * * * * * * 44 * 37 0 * * * * * * 4086 0 0 A 38 3309 5442 * 5106 * * * * 3350 5912 * * * 2917 3246 2655 2128 3223 * * 38 0 * * * * * * 4086 0 0 Y 39 * * * * 2300 * * 4080 * 4218 5295 * * * * * * * * 603 39 0 * * * * * * 4086 0 0 G 40 * * * * * 181 * * * * * 4356 * * * 3859 * * * * 40 0 * * * * * * 4086 0 0 P 41 * * 2988 4927 * * 4299 * 5172 * * 3300 966 * 5373 3687 4404 * * * 41 0 * * * * * * 4086 0 0 V 42 4957 * * * 5309 * * 2089 * 4144 5411 * * * * 3886 5373 900 * * 42 0 * * * * * * 4086 0 0 Y 43 5172 4298 * * * 5046 4071 5306 * * * * * 3952 4315 2159 1421 4231 * 4607 43 0 * * * * * * 4086 0 0 S 44 5106 1347 * 4365 4299 * * * * * * * * * * 1506 5060 4535 * 4232 44 0 * * * * * * 4086 0 0 S 45 2369 3357 * * 5597 * 5912 5249 4170 4299 * * * * * 1366 4447 4487 * 4046 45 0 * * * * * * 4086 0 0 L 46 1744 * * * * 4403 4299 * * 1162 * 4814 * * 5088 * 4434 4461 * * 46 0 * * * * * * 4086 0 0 Y 47 * * * * 5106 * * * * 4814 5088 * * * * * * * * 142 47 0 * * * * * * 4086 0 0 D 48 * * 1008 * * * * * * * * 4279 1148 * * * * * * * 48 0 * * * * * * 4086 0 0 L 49 * * * * * * * * * 117 4299 * * * * * 5198 * * * 49 0 * * * * * * 4086 0 0 S 50 3134 * 5060 5373 5309 6322 * * 3300 5943 * 3839 * * 5521 2208 1815 * 5106 4176 50 0 * * * * * * 4086 0 0 S 51 5630 4472 2401 2840 * 3456 4388 5172 4350 6322 5943 4297 * 4964 * 1972 5411 * * * 51 0 * * * * * * 4086 0 0 L 52 * * * * * * * 1296 * 1514 * * * * * * * 2044 * * 52 0 * * * * * * 4086 0 0 D 53 * * 0 * * * * * * * * * * * * * * * * * 53 0 * * * * * * 4086 0 0 T 54 * * * * * * * * * * * * * * * 1048 954 * * * 54 40 * 5198 * * * * 4086 0 0 C 55 * 3515 * * 5586 * * 1233 * 5615 * * * * 5310 5074 3188 3485 3196 3593 55 574 2751 2475 2128 375 0 * 4079 2242 1000 G 56 * * 2323 3523 * 1668 * * * * * 2498 4243 * * * 2837 5117 * * 56 484 1812 * 2528 275 0 * 3969 2671 1947 E 57 3194 * 2273 1990 * 3640 5597 * * * * 1923 * 4457 * 5503 * * * * 57 77 5219 5325 2585 263 * * 4086 1234 0 E 58 * 4323 5872 2207 * * * * 2438 5398 * 4495 * 2629 3006 3241 * * 4380 5397 58 139 3448 * 2454 291 0 * 4079 1935 1000 A 59 3816 * 3464 5403 * 4331 5322 * 2445 4144 * 1789 3796 5060 * 3636 5157 * * * 59 0 * * * * * * 4086 0 0 S 60 * * * * * 4365 * * * * * * * 5106 * 116 * * * * 60 52 4814 * 2322 322 * * 4086 1000 0 V 61 1059 * * * 5249 * * * * 4365 * * * * * * * 1168 * * 61 0 * * * * * * 4086 0 0 L 62 * * * * * * * 3548 * 353 4472 * * * * * * 3533 * * 62 40 * 5207 * * * * 4086 0 0 E 63 4275 * 3070 1241 4364 * * * 4055 * 3720 3644 * * * 3097 5334 * * * 63 0 * * * * 0 * 4059 0 1000 I 64 * * * 5088 5943 * * 978 5521 2250 * 5256 * * 5106 * 4339 3183 * * 64 43 5106 * 2000 415 * * 4086 1000 0 L 65 4388 * * * * * * 1498 * 2240 * * * 5207 * * 4420 1677 * * 65 0 * * * * * * 4086 0 0 V 66 3319 4170 * * * * * 2558 * 4609 * * * * * * 3713 844 * * 66 30 * 5588 * * * * 4086 0 0 Y 67 5389 * 4183 * 3148 * * 4125 * * * 3803 * 4396 4102 4238 3313 * * 1252 67 29 5629 * 0 * 0 * 4087 1000 1000 N 68 * * * * * 1406 3660 * * * * 3390 * 5270 * 1342 * * * 5172 68 90 * 4040 * * * * 4086 0 0 S 69 5546 5393 2349 2841 * * 5201 * 3600 * * 2811 4157 5881 * 2183 3766 * * * 69 227 4312 3396 2322 322 946 1056 3994 1000 1634 K 70 * * 2666 3862 * * * * 1594 * * 2415 * * 4214 4595 3290 4124 * * 70 176 * 3124 * * 820 1206 3903 0 2365 I 71 * * * * * * * 2258 4187 5388 * 3571 * 4026 3542 2139 3045 2917 * * 71 85 * 4132 * * 602 1552 3917 0 2523 E 72 4020 * 2201 2319 * 4058 4839 4248 5671 * * 4133 1905 5094 * * * * * * 72 29 * 5640 * * 368 2152 3921 0 2173 N 73 3521 * * 2224 * 5239 2655 * 3307 * * 1558 * * 5730 * * 5225 5192 * 73 40 * 5197 * * 0 * 4000 0 1503 R 74 3681 * * * * * 1360 * * 5164 * * * 5015 1476 * 3593 * * 4996 74 124 * 3602 * * * 0 4016 0 1000 H 75 4181 4884 * 4845 * 5096 2534 4513 * 994 * 4654 4951 * * * * * * 4146 75 58 * 4654 * * 460 1872 3928 0 2066 E 76 * * 2039 1482 * * * * 2870 5086 * 3498 5171 5014 4211 4993 * * * * 76 0 * * * * 946 1056 3980 0 1591 M 77 * 4169 * * * * * 4209 * 1858 703 * * * * * * * * * 77 43 * 5092 * * 0 * 4016 0 1000 L 78 * * * * * * * 2369 * 667 4583 * * * * * * 2889 * * 78 0 * * * * * 0 3992 0 1000 A 79 4378 * 1955 2625 * 5056 * * * 5404 * 5098 * 2198 * 2731 5099 4283 * * 79 75 * 4311 * * 0 * 3992 0 1000 V 80 3844 * * * * 2837 4261 2452 4793 2368 * 4935 * 4844 * 3915 3618 3178 * * 80 0 * * * * 0 * 4037 0 1304 E 81 5250 * 4889 1730 * 2501 * 4706 * 4939 * 5024 2843 4822 * * 2430 * * * 81 0 * * * * * * 4050 0 0 P 82 * * * * * * * 5224 * 3002 * * 960 * * * * 1581 * * 82 48 4939 * 1000 1000 * * 4050 1000 0 I 83 * * * * * * * 1194 * 1208 4909 * * * * * * 3371 * * 83 0 * * * * * * 4050 0 0 N 84 * * 4822 4939 5123 4180 4032 * 2044 * * 2249 * 4096 3307 * 3899 3710 * 5003 84 0 * * * * * * 4050 0 0 E 85 4363 * * 1567 * * * 4706 3557 * * * * 2319 2145 4892 5041 * * * 85 0 * * * * * * 4050 0 0 L 86 * * * * * * * 5167 * 115 * * * * * * * 4363 * * 86 0 * * * * * * 4050 0 0 L 87 * * * * * * * 3000 * 484 * * * * * * 4706 3037 * * 87 0 * * * * * * 4050 0 0 R 88 3515 * 3648 2122 * * 2341 * * * * 3143 * 2490 4366 4898 4949 * * * 88 0 * * * * * * 4050 0 0 D 89 4218 * 3102 1717 4850 * 4856 * 4200 3576 5002 * * 4218 4752 5212 * 3788 * 3371 89 0 * * * * * * 4009 0 0 K 90 * * * * * * * * 0 * * * * * * * * * * * 90 0 * * 0 * * * 4009 0 0 //