HHsearch 1.5 NAME c9fqlI_ FAM FILE c9fqlI_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9fqlI_.a3m DATE Sat Jul 5 09:22:59 2025 LENG 86 match states, 86 columns in multiple alignment FILT 11 out of 13 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 2.7 EVD 0.4416 1.7041 SEQ >ss_pred CCCCCCCHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC >ss_conf 97304768999863432888613329999999999997665117027546760785467874888620126699999975312039 >Consensus xxxVrpkxxLlxxLxxxGAxgxxfTxkqVmxYLgqYIxxkxLydxxxqhiVxCxxDxLGxllgvxsFsVkxxxxlxxxlxxnLxxv >c9fqlI_ ETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGAPSFSVKEHRKIYTMIYRNLVVV >UniRef50_O42354(18-103:445) E3 ubiquitin-protein ligase Mdm2 n=2 Tax=Danio rerio RepID=MDM2_DANRE E=4e-24 s/c=1.30 id=60% cov=101% EKLVRPKVQLKSLLEDAGADKDVFTMKEVMFYLGKYIMSKELYDKQQQHIVHCGEDPLGAVLGVKSFSVKEPRALFALINRNLVTV >UniRef50_Q7ZYI3(25-110:475) Protein Mdm4 n=5 Tax=Xenopus RepID=MDM4_XENLA E=9e-22 s/c=1.21 id=53% cov=101% ESLVRVQPALLKILQSAGAKGDMFTLKQVMHYLGQYIMVKGLYDKQHQHIVHCGSDELGKLLGITTFSVKDPRPLYDMLKKNLLRI >UniRef50_UPI000180B5D3(9-88:404) PREDICTED: similar to E3 ubiquitin-protein ligase Mdm2 (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) n=1 Tax=Ciona intestinalis RepID=UPI000180B5D3 E=7e-25 s/c=1.43 id=31% cov=94% ----RTTPKLLAVLQMGGASGQIFTADQIVLFLGKYIETKKLFNPSNKRLIRCKNDLLGEVFKTSHFTVTDFKDLWKLLFPSLL-- >UniRef50_C3Y7L6(89-163:400) Putative uncharacterized protein n=1 Tax=Branchiostoma floridae RepID=C3Y7L6_BRAFL E=8e-24 s/c=1.48 id=37% cov=88% ---VCPKPALLNCLQKVGATGTCFTRKQVLNYLIQYMGERMLYDQNNPRVINCKDDELGKALGVPQFTIYNVKEVLAA-------- >UniRef50_B7QMD7(32-77:448) Ubiquitin protein ligase E3 mdm2, putative n=1 Tax=Ixodes scapularis RepID=B7QMD7_IXOSC E=4e-06 s/c=1.14 id=36% cov=55% ---------------------------QILGHLKSYILERQLFDPKDPKMVLCANDKLGKVFGVEQFLAEEVK------------- >UniRef50_B3RT05(52-132:458) Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens RepID=B3RT05_TRIAD E=5e-22 s/c=1.30 id=26% cov=95% --VVKPNAELMQFLPPENVNGKELTALQVMEYLIDYISSRKLCNPLRADYVDCKGDPLEKLLSCDQFPVAN---LWDRLKMHLEVV >UniRef50_Q7ZUW7(6-169:496) Protein Mdm4 n=13 Tax=Clupeocephala RepID=MDM4_DANRE E=1e-44 s/c=0.79 id=52% cov=101% GTQVHPRAPLLQILKVAGAQEEVFTLKEVMHYLGQYIMMKQLYDKQRQHIVHCHDDPLGELLEVGSFSVKNPSPVYEMLKRNLVIL >UniRef50_UPI00017B5A2E(17-121:425) UPI00017B5A2E related cluster n=1 Tax=Tetraodon nigroviridis RepID=UPI00017B5A2E E=1e-37 s/c=1.11 id=56% cov=101% YKLVRPKVEFHSLLQHAGATKEVFTMKEVMFYLGQYIIQKQLYDQKQQHIVHCSHDELGRVLGVDSFSVKEPRVLFAALMKNLVAV >UniRef50_O15151(1-192:490) Protein Mdm4 n=39 Tax=Amniota RepID=MDM4_HUMAN E=2e-29 s/c=0.59 id=54% cov=101% INQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVtLA # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * E 1 * * * 835 * 2711 * 2815 * * * * * * * * * * * 2791 1 0 * * * * * * 1886 0 0 T 2 2904 * * * * * * * 1819 * * 2815 * * * 2757 1771 * * * 2 0 * * * * * * 1886 0 0 L 3 * * * * * * * * * 857 * * * 2160 * * * 2159 * * 3 0 * * * * * * 2242 0 0 V 4 * * * * * * * * * * * * * * * * * 0 * * 4 0 * * * * * * 2438 0 0 R 5 * 3006 * * * * 3579 * 2074 * * * * * 851 * * * * * 5 0 * * * * * * 2684 0 0 P 6 * * * * * * * * * * * * 378 * * * 2732 3647 * * 6 0 * * * * * * 2684 0 0 K 7 * * * * * * * * 919 * * 2669 * 3647 3579 * 2732 * * * 7 0 * * * * * * 2684 0 0 P 8 2054 * * * * * * * * 3692 * * 956 * * * * 2589 * * 8 0 * * * * * * 2684 0 0 L 9 2291 * * 2053 * * * * 2732 2637 * * 2635 3601 * * * * * * 9 0 * * * * * * 2684 0 0 L 10 * * * * 3578 * * * * 126 * * * * * * * * * * 10 0 * * * * * * 2684 0 0 L 11 * * * * * * 3578 * 3601 564 2669 * * * * * * * * * 11 0 * * * * * * 2684 0 0 K 12 2732 * * * * * * * 1653 * * 3006 * 2054 * 2589 * * * * 12 0 * * * * * * 2684 0 0 L 13 * 3006 * * 2669 * * 2054 * 1613 * * * * * * * 2732 * * 13 0 * * * * * * 2684 0 0 L 14 * * * * * * * * * 0 * * * * * * * * * * 14 0 * * * * * * 2684 0 0 K 15 * * * 3601 * * 3692 * 2032 * * * 2669 1189 * * * * * * 15 0 * * * * * * 2684 0 0 S 16 3692 * 3601 * * * 3578 * 3006 3640 2732 * 2669 * * 2640 * 3579 * * 16 0 * * * * * * 2684 0 0 V 17 1037 * * 2669 * 2732 * * * * * * * * * * * 2286 * * 17 0 * * * * * * 2684 0 0 G 18 * * * * * 247 * * * * * 2669 * * * * * * * * 18 0 * * * * * * 2684 0 0 A 19 247 * * * * * * * * * * * * * * * * 2669 * * 19 0 * * * * * * 2684 0 0 Q 20 * * 3601 3640 * * * * 3647 * * 2669 * 2049 * 2732 2264 * * * 20 0 * * * * * * 2684 0 0 K 21 * * * 3579 * 763 * * 1613 * * * * * * * * * * * 21 0 * * * * * * 2684 0 0 D 22 * * 1630 2031 * * * * 2669 * * * * 2732 * * 3006 * * * 22 0 * * * * * * 2684 0 0 T 23 * 3006 * 2669 * * * 2732 * * 2669 * * * * * 2637 2001 * * 23 0 * * * * * * 2684 0 0 Y 24 * * * * 392 * * * * 2669 * * * * * * * * * 3634 24 0 * * * * * * 2684 0 0 T 25 * * * * * * * * * * * * * * * * 0 * * * 25 0 * * * * * * 2684 0 0 M 26 1700 * * * * * * * * 2613 1613 * * * 3006 * * 3692 * * 26 0 * * * * * * 2684 0 0 K 27 * * 2732 * * * * * 531 2669 * * * * * * * * * * 27 0 * * * * * * 2684 0 0 E 28 * * * 1155 * * * * * * * * * 860 * * * * * * 28 0 * * * * * * 2821 0 0 V 29 * * * * * * * 2224 * * * * * * * * * 348 * * 29 0 * * * * * * 2821 0 0 L 30 * * * * * * * 3847 * 1882 929 * * * * * * 2900 * * 30 0 * * * * * * 2821 0 0 F 31 * * * 2791 1750 3642 2144 * * 2900 * 3085 * * * * * * * * 31 0 * * * * * * 2821 0 0 Y 32 * * * * 2900 * 3642 * * * * * * * * * * * * 348 32 0 * * * * * * 2821 0 0 L 33 * * * * * * * * * 0 * * * * * * * * * * 33 0 * * * * * * 2821 0 0 G 34 * * * * * 605 * 1931 3642 * * * * * * * * * * * 34 0 * * * * * * 2821 0 0 Q 35 * * 2791 * * * * * 2251 * * * * 823 * 3642 * * * * 35 0 * * * * * * 2821 0 0 Y 36 * * * * * * * * * * * * * * * * * * * 0 36 0 * * * * * * 2821 0 0 I 37 * * * * * * * 181 * * 3085 * * * * * * * * * 37 0 * * * * * * 2821 0 0 M 38 * * * 2900 * 3085 * 3676 * 3642 1167 * * * * 2791 * * * * 38 0 * * * * * * 2821 0 0 T 39 * * * 2337 * * * * * * 3631 * * 3676 * 1786 2269 2780 * * 39 0 * * * * * * 2821 0 0 K 40 * * * * * * * * 605 * * * * * 1546 * * * * * 40 0 * * * * * * 2821 0 0 R 41 * * * 3716 * 3743 * * 1844 * 3085 * * 1398 3766 * * * * * 41 0 * * * * * * 2821 0 0 L 42 * * * * * * * * * 0 * * * * * * * * * * 42 0 * * * * * * 2821 0 0 Y 43 * 2791 * * 2224 * * * * * * * * * * * * * * 641 43 0 * * * * * * 2821 0 0 D 44 * * 471 * * * * * * * * 1844 * * * * * * * * 44 0 * * * * * * 2821 0 0 E 45 * * * 2806 * * * * 2111 * * * 1480 1905 * * * * * * 45 0 * * * * * * 2821 0 0 K 46 * * * * * * * * 1731 2791 * 3085 * 1725 * 2900 * * * * 46 0 * * * * * * 2821 0 0 Q 47 * * 3642 2833 * * 3743 * * * * 1989 * 2134 2151 * * * * * 47 0 * * * * * * 2821 0 0 Q 48 2791 * * * * * * * 2900 * * * 2337 933 * * * * * * 48 0 * * * * * * 2821 0 0 H 49 * * 2791 * * * 933 * 3642 * * * * * 1989 * * * * * 49 0 * * * * * * 2821 0 0 I 50 * * * * * * * 1143 * 2900 2728 * * * * * * 3085 * 2791 50 0 * * * * * * 2821 0 0 V 51 * * * * * * * 1989 * * * * * * * * * 419 * * 51 0 * * * * * * 2821 0 0 Y 52 * * 2791 * * * 1399 * * 3642 * 3085 * * 2900 * * * * 2792 52 0 * * * * * * 2821 0 0 C 53 * 0 * * * * * * * * * * * * * * * * * * 53 0 * * * * * * 2821 0 0 S 54 2741 * * * * 2173 3631 * 1335 * * * * * * 2721 * * * * 54 0 * * * * * * 2821 0 0 N 55 * * 2332 3716 * 2215 3676 * * * * 1486 * * * 3743 * * * * 55 0 * * * * * * 2821 0 0 D 56 * * 0 * * * * * * * * * * * * * * * * * 56 0 * * * * * * 2821 0 0 L 57 * * * 1885 * * * * 3642 1523 * * 1731 * * * * * * * 57 0 * * * * * * 2821 0 0 L 58 * * * * * * * * * 0 * * * * * * * * * * 58 0 * * * * * * 2821 0 0 G 59 * * * 2791 * 225 * * * * * * * * * * * * * * 59 0 * * * * * * 2821 0 0 D 60 3716 * 2806 1808 * * * * 1262 * * * * * 3676 * * * * * 60 0 * * * * * * 2821 0 0 L 61 3085 * * * * * * * * 961 * * * * * * * 1441 * * 61 0 * * * * * * 2821 0 0 F 62 * * * * 1486 * * * * 637 * * * * * * * * * * 62 0 * * * * * * 2821 0 0 G 63 * * * 3631 * 642 * * 2900 * * * * * * 2791 * * * * 63 0 * * * * * * 2821 0 0 A 64 3766 2791 * * * * * 3743 * * * * * * 3818 * 2900 993 * * 64 0 * * * * * * 2821 0 0 P 65 * * 2167 3642 * 3631 * * 3716 * * * 2386 3818 * 2900 2794 * * * 65 0 * * * * * * 2821 0 0 S 66 * * * * * * 2900 * * * * * * 1546 * 1155 3743 * * * 66 0 * * * * * * 2821 0 0 F 67 * * * * 0 * * * * * * * * * * * * * * * 67 0 * * * * * * 2821 0 0 S 68 * * * * * * * * * 3642 * * 2791 * * 933 1989 * * * 68 0 * * * * * * 2821 0 0 V 69 3642 * * * * * * 3085 * * * * * * * * * 318 * * 69 0 * * * * * * 2821 0 0 K 70 2791 * * 3642 * * * * 933 * * * * * * * 2900 * * 3085 70 0 * * * * * * 2821 0 0 E 71 * * 1839 1406 * * * * * * * 1544 * * * * * * * * 71 225 * 2791 * * * * 2821 0 0 H 72 * * * * 2614 * 2605 * * * * * 1177 * * * * 2120 * * 72 0 * * * * * 0 2549 0 1000 R 73 * * * * * * * * 1346 * * * * * 1225 2483 * * * * 73 0 * * * * * 0 2549 0 1000 K 74 3408 * 2430 2619 * * * * 3458 * * * 1824 * 3517 * * 3372 * * 74 0 * * * * 0 * 2451 0 1000 I 75 * * * * * * * 2637 * 664 * * * * * * * 2265 * * 75 0 * * * * * * 2684 0 0 Y 76 * * * * 2589 * * * * 3006 * * * * * * * * 1700 1316 76 0 * * * * * * 2684 0 0 T 77 1783 * 1669 3579 * * * * 2732 * * * * * * 3640 3634 * * * 77 0 * * * * * * 2684 0 0 M 78 2264 * * * * * * * * 2102 1316 * * * 2669 * * * * * 78 0 * * * * * * 2684 0 0 I 79 * * * * * * * 1881 * 457 * * * * * * * * * * 79 0 * * * * * * 2554 0 0 Y 80 * * * * 2483 * * * 1447 * 3371 3460 * * 3534 3504 * * * 3435 80 0 * * * * * * 2554 0 0 R 81 * * * * * * * * 1871 * 2471 * 2483 * 1445 * * * * * 81 0 * * * * * * 2554 0 0 N 82 * * * * * * 2471 * * * * 642 * * * 2483 * * * * 82 0 * * * * * * 2554 0 0 L 83 * * * * * * * * * 0 * * * * * * * * * * 83 0 * * * * * * 2554 0 0 V 84 * * * 2471 * * * 3504 * 1893 * * * * * * * 1113 * * 84 160 3249 * 0 * * * 2554 1000 0 V 85 2199 * * * * * * 3112 * 3209 * * * * 3144 * 3186 1576 * * 85 0 * * * * * * 2242 0 0 V 86 3209 * * * * * * 2193 * 3112 * * * * * * * 843 * * 86 0 * * 0 * * * 2242 0 0 //