HHsearch 1.5 NAME c9fqlE_ FAM FILE c9fqlE_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9fqlE_.a3m DATE Sat Jul 5 10:44:24 2025 LENG 85 match states, 85 columns in multiple alignment FILT 11 out of 13 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 2.7 EVD 0.4258 1.0542 SEQ >ss_pred CCCCCCHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC >ss_conf 9745758999863432888612329999999999997666117027546760785468874888621126699999976312039 >Consensus xxVrpkxxLlxxLxxxGAxgxxfTxkqVmxYLgqYIxxkxLydxxxqhiVxCxxDxLGxllgvxsFsVkxxxxlxxxlxxnLxxv >c9fqlE_ TLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGAPSFSVKEHRKIYTMIYRNLVVV >UniRef50_Q7ZUW7(22-106:496) Protein Mdm4 n=13 Tax=Clupeocephala RepID=MDM4_DANRE E=6e-31 s/c=1.59 id=52% cov=101% TQVHPRAPLLQILKVAGAQEEVFTLKEVMHYLGQYIMMKQLYDKQRQHIVHCHDDPLGELLEVGSFSVKNPSPVYEMLKRNLVIL >UniRef50_UPI000180B5D3(9-88:404) PREDICTED: similar to E3 ubiquitin-protein ligase Mdm2 (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) n=1 Tax=Ciona intestinalis RepID=UPI000180B5D3 E=7e-25 s/c=1.44 id=31% cov=95% ---RTTPKLLAVLQMGGASGQIFTADQIVLFLGKYIETKKLFNPSNKRLIRCKNDLLGEVFKTSHFTVTDFKDLWKLLFPSLL-- >UniRef50_C3Y7L6(89-163:400) Putative uncharacterized protein n=1 Tax=Branchiostoma floridae RepID=C3Y7L6_BRAFL E=7e-24 s/c=1.48 id=37% cov=89% --VCPKPALLNCLQKVGATGTCFTRKQVLNYLIQYMGERMLYDQNNPRVINCKDDELGKALGVPQFTIYNVKEVLAA-------- >UniRef50_B3RT05(52-132:458) Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens RepID=B3RT05_TRIAD E=3e-06 s/c=0.65 id=26% cov=96% -VVKPNAELMQFLPPENVNGKELTALQVMEYLIDYISSRKLCNPLRADYVDCKGDPLEKLLSCDQFPVAN---LWDRLKMHLEVV >UniRef50_B7QMD7(32-77:448) Ubiquitin protein ligase E3 mdm2, putative n=1 Tax=Ixodes scapularis RepID=B7QMD7_IXOSC E=4e-06 s/c=1.14 id=36% cov=55% --------------------------QILGHLKSYILERQLFDPKDPKMVLCANDKLGKVFGVEQFLAEEVK------------- >UniRef50_B0R0S8(3-183:475) Double minute 2 homolog n=13 Tax=Clupeocephala RepID=B0R0S8_DANRE E=8e-34 s/c=0.43 id=59% cov=101% KLVRPKVQLKSLLEDAGADKDVFTMKEVMFYLGKYIMSKELYDKQQQHIVHCGEDPLGAVLGVKSFSVKEPRALFALINRNLVTV >UniRef50_UPI00017B5A2E(17-109:425) UPI00017B5A2E related cluster n=1 Tax=Tetraodon nigroviridis RepID=UPI00017B5A2E E=2e-23 s/c=0.86 id=57% cov=101% KLVRPKVEFHSLLQHAGATKEVFTMKEVMFYLGQYIIQKQLYDQKQQHIVHCSHDELGRVLGVDSFSVKEPRVLFAALMKNLVAV >UniRef50_Q7ZYI3(14-127:475) Protein Mdm4 n=5 Tax=Xenopus RepID=MDM4_XENLA E=6e-43 s/c=0.99 id=52% cov=101% SLVRVQPALLKILQSAGAKGDMFTLKQVMHYLGQYIMVKGLYDKQHQHIVHCGSDELGKLLGITTFSVKDPRPLYDMLKKNLLRI >UniRef50_O15151(1-192:490) Protein Mdm4 n=39 Tax=Amniota RepID=MDM4_HUMAN E=2e-29 s/c=0.60 id=55% cov=101% NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVtLA # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * T 1 2895 * * * * * * * 1821 * * 2827 * * * 2747 1773 * * * 1 0 * * * * * * 1874 0 0 L 2 * * * * * * * * * 857 * * * 2160 * * * 2159 * * 2 0 * * * * * * 2242 0 0 V 3 * * * * * * * * * * * * * * * * * 0 * * 3 0 * * * * * * 2438 0 0 R 4 * 3006 * * * * 3579 * 2074 * * * * * 851 * * * * * 4 0 * * * * * * 2684 0 0 P 5 * * * * * * * * * * * * 378 * * * 2732 3647 * * 5 0 * * * * * * 2684 0 0 K 6 * * * * * * * * 919 * * 2669 * 3647 3579 * 2732 * * * 6 0 * * * * * * 2684 0 0 P 7 2054 * * * * * * * * 3692 * * 956 * * * * 2589 * * 7 0 * * * * * * 2684 0 0 L 8 2291 * * 2053 * * * * 2732 2637 * * 2635 3601 * * * * * * 8 0 * * * * * * 2684 0 0 L 9 * * * * 3578 * * * * 126 * * * * * * * * * * 9 0 * * * * * * 2684 0 0 L 10 * * * * * * 3578 * 3601 564 2669 * * * * * * * * * 10 0 * * * * * * 2684 0 0 K 11 2732 * * * * * * * 1653 * * 3006 * 2054 * 2589 * * * * 11 0 * * * * * * 2684 0 0 L 12 * 3006 * * 2669 * * 2054 * 1613 * * * * * * * 2732 * * 12 0 * * * * * * 2684 0 0 L 13 * * * * * * * * * 0 * * * * * * * * * * 13 0 * * * * * * 2684 0 0 K 14 * * * 3601 * * 3692 * 2032 * * * 2669 1189 * * * * * * 14 0 * * * * * * 2684 0 0 S 15 3692 * 3601 * * * 3578 * 3006 3640 2732 * 2669 * * 2640 * 3579 * * 15 0 * * * * * * 2684 0 0 V 16 1037 * * 2669 * 2732 * * * * * * * * * * * 2286 * * 16 0 * * * * * * 2684 0 0 G 17 * * * * * 247 * * * * * 2669 * * * * * * * * 17 0 * * * * * * 2684 0 0 A 18 247 * * * * * * * * * * * * * * * * 2669 * * 18 0 * * * * * * 2684 0 0 Q 19 * * 3601 3640 * * * * 3647 * * 2669 * 2049 * 2732 2264 * * * 19 0 * * * * * * 2684 0 0 K 20 * * * 3579 * 763 * * 1613 * * * * * * * * * * * 20 0 * * * * * * 2684 0 0 D 21 * * 1630 2031 * * * * 2669 * * * * 2732 * * 3006 * * * 21 0 * * * * * * 2684 0 0 T 22 * 3006 * 2669 * * * 2732 * * 2669 * * * * * 2637 2001 * * 22 0 * * * * * * 2684 0 0 Y 23 * * * * 392 * * * * 2669 * * * * * * * * * 3634 23 0 * * * * * * 2684 0 0 T 24 * * * * * * * * * * * * * * * * 0 * * * 24 0 * * * * * * 2684 0 0 M 25 1700 * * * * * * * * 2613 1613 * * * 3006 * * 3692 * * 25 0 * * * * * * 2684 0 0 K 26 * * 2732 * * * * * 531 2669 * * * * * * * * * * 26 0 * * * * * * 2684 0 0 E 27 * * * 1155 * * * * * * * * * 860 * * * * * * 27 0 * * * * * * 2821 0 0 V 28 * * * * * * * 2224 * * * * * * * * * 348 * * 28 0 * * * * * * 2821 0 0 L 29 * * * * * * * 3847 * 1882 929 * * * * * * 2900 * * 29 0 * * * * * * 2821 0 0 F 30 * * * 2791 1750 3642 2144 * * 2900 * 3085 * * * * * * * * 30 0 * * * * * * 2821 0 0 Y 31 * * * * 2900 * 3642 * * * * * * * * * * * * 348 31 0 * * * * * * 2821 0 0 L 32 * * * * * * * * * 0 * * * * * * * * * * 32 0 * * * * * * 2821 0 0 G 33 * * * * * 605 * 1931 3642 * * * * * * * * * * * 33 0 * * * * * * 2821 0 0 Q 34 * * 2791 * * * * * 2251 * * * * 823 * 3642 * * * * 34 0 * * * * * * 2821 0 0 Y 35 * * * * * * * * * * * * * * * * * * * 0 35 0 * * * * * * 2821 0 0 I 36 * * * * * * * 181 * * 3085 * * * * * * * * * 36 0 * * * * * * 2821 0 0 M 37 * * * 2900 * 3085 * 3676 * 3642 1167 * * * * 2791 * * * * 37 0 * * * * * * 2821 0 0 T 38 * * * 2337 * * * * * * 3631 * * 3676 * 1786 2269 2780 * * 38 0 * * * * * * 2821 0 0 K 39 * * * * * * * * 605 * * * * * 1546 * * * * * 39 0 * * * * * * 2821 0 0 R 40 * * * 3716 * 3743 * * 1844 * 3085 * * 1398 3766 * * * * * 40 0 * * * * * * 2821 0 0 L 41 * * * * * * * * * 0 * * * * * * * * * * 41 0 * * * * * * 2821 0 0 Y 42 * 2791 * * 2224 * * * * * * * * * * * * * * 641 42 0 * * * * * * 2821 0 0 D 43 * * 471 * * * * * * * * 1844 * * * * * * * * 43 0 * * * * * * 2821 0 0 E 44 * * * 2806 * * * * 2111 * * * 1480 1905 * * * * * * 44 0 * * * * * * 2821 0 0 K 45 * * * * * * * * 1731 2791 * 3085 * 1725 * 2900 * * * * 45 0 * * * * * * 2821 0 0 Q 46 * * 3642 2833 * * 3743 * * * * 1989 * 2134 2151 * * * * * 46 0 * * * * * * 2821 0 0 Q 47 2791 * * * * * * * 2900 * * * 2337 933 * * * * * * 47 0 * * * * * * 2821 0 0 H 48 * * 2791 * * * 933 * 3642 * * * * * 1989 * * * * * 48 0 * * * * * * 2821 0 0 I 49 * * * * * * * 1143 * 2900 2728 * * * * * * 3085 * 2791 49 0 * * * * * * 2821 0 0 V 50 * * * * * * * 1989 * * * * * * * * * 419 * * 50 0 * * * * * * 2821 0 0 Y 51 * * 2791 * * * 1399 * * 3642 * 3085 * * 2900 * * * * 2792 51 0 * * * * * * 2821 0 0 C 52 * 0 * * * * * * * * * * * * * * * * * * 52 0 * * * * * * 2821 0 0 S 53 2741 * * * * 2173 3631 * 1335 * * * * * * 2721 * * * * 53 0 * * * * * * 2821 0 0 N 54 * * 2332 3716 * 2215 3676 * * * * 1486 * * * 3743 * * * * 54 0 * * * * * * 2821 0 0 D 55 * * 0 * * * * * * * * * * * * * * * * * 55 0 * * * * * * 2821 0 0 L 56 * * * 1885 * * * * 3642 1523 * * 1731 * * * * * * * 56 0 * * * * * * 2821 0 0 L 57 * * * * * * * * * 0 * * * * * * * * * * 57 0 * * * * * * 2821 0 0 G 58 * * * 2791 * 225 * * * * * * * * * * * * * * 58 0 * * * * * * 2821 0 0 D 59 3716 * 2806 1808 * * * * 1262 * * * * * 3676 * * * * * 59 0 * * * * * * 2821 0 0 L 60 3085 * * * * * * * * 961 * * * * * * * 1441 * * 60 0 * * * * * * 2821 0 0 F 61 * * * * 1486 * * * * 637 * * * * * * * * * * 61 0 * * * * * * 2821 0 0 G 62 * * * 3631 * 642 * * 2900 * * * * * * 2791 * * * * 62 0 * * * * * * 2821 0 0 A 63 3766 2791 * * * * * 3743 * * * * * * 3818 * 2900 993 * * 63 0 * * * * * * 2821 0 0 P 64 * * 2167 3642 * 3631 * * 3716 * * * 2386 3818 * 2900 2794 * * * 64 0 * * * * * * 2821 0 0 S 65 * * * * * * 2900 * * * * * * 1546 * 1155 3743 * * * 65 0 * * * * * * 2821 0 0 F 66 * * * * 0 * * * * * * * * * * * * * * * 66 0 * * * * * * 2821 0 0 S 67 * * * * * * * * * 3642 * * 2791 * * 933 1989 * * * 67 0 * * * * * * 2821 0 0 V 68 3642 * * * * * * 3085 * * * * * * * * * 318 * * 68 0 * * * * * * 2821 0 0 K 69 2791 * * 3642 * * * * 933 * * * * * * * 2900 * * 3085 69 0 * * * * * * 2821 0 0 E 70 * * 1839 1406 * * * * * * * 1544 * * * * * * * * 70 225 * 2791 * * * * 2821 0 0 H 71 * * * * 2614 * 2605 * * * * * 1177 * * * * 2120 * * 71 0 * * * * * 0 2549 0 1000 R 72 * * * * * * * * 1346 * * * * * 1225 2483 * * * * 72 0 * * * * * 0 2549 0 1000 K 73 3408 * 2430 2619 * * * * 3458 * * * 1824 * 3517 * * 3372 * * 73 0 * * * * 0 * 2451 0 1000 I 74 * * * * * * * 2637 * 664 * * * * * * * 2265 * * 74 0 * * * * * * 2684 0 0 Y 75 * * * * 2589 * * * * 3006 * * * * * * * * 1700 1316 75 0 * * * * * * 2684 0 0 T 76 1783 * 1669 3579 * * * * 2732 * * * * * * 3640 3634 * * * 76 0 * * * * * * 2684 0 0 M 77 2264 * * * * * * * * 2102 1316 * * * 2669 * * * * * 77 0 * * * * * * 2684 0 0 I 78 * * * * * * * 1881 * 457 * * * * * * * * * * 78 0 * * * * * * 2554 0 0 Y 79 * * * * 2483 * * * 1447 * 3371 3460 * * 3534 3504 * * * 3435 79 0 * * * * * * 2554 0 0 R 80 * * * * * * * * 1871 * 2471 * 2483 * 1445 * * * * * 80 0 * * * * * * 2554 0 0 N 81 * * * * * * 2471 * * * * 642 * * * 2483 * * * * 81 0 * * * * * * 2554 0 0 L 82 * * * * * * * * * 0 * * * * * * * * * * 82 0 * * * * * * 2554 0 0 V 83 * * * 2471 * * * 3504 * 1893 * * * * * * * 1113 * * 83 160 3249 * 0 * * * 2554 1000 0 V 84 2199 * * * * * * 3112 * 3209 * * * * 3144 * 3186 1576 * * 84 0 * * * * * * 2242 0 0 V 85 3209 * * * * * * 2193 * 3112 * * * * * * * 843 * * 85 0 * * 0 * * * 2242 0 0 //