HHsearch 1.5 NAME c9dpuA_ FAM FILE c9dpuA_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9dpuA_.a3m DATE Sat Mar 8 12:02:36 2025 LENG 105 match states, 105 columns in multiple alignment FILT 103 out of 349 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 6.6 EVD 0.4142 -0.4563 SEQ >ss_pred CCCEEECEEEEHHHCCCCCEEECCCCEECEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCEEE EEECC >ss_conf 9744221068785619873384168620103342458766567776424578888731263337778615502553159998589989999972782895 42219 >Consensus sxCcrxxxxVxFxxlGWxxwIixPxxxxaxyCxGxCxxxxxxxxxxxxhaxxxxxxxxxxxxxxxxpCCxPtxxxxlxilyxdxxgxxxxxxxxxxmvvx xCgCr >c9dpuA_ SHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVSKACCVPTKLSPISVLYKDDMGVPTLKYHYEGMSVA ECGCR >UniRef50_P38440(159-264:265) Inhibin alpha chain (Fragment) n=9 Tax=Theria RepID=INHA_SHEEP E=5e-17 s/c=0.84 id=26% cov=100% ADCHRAALNISFQELGWDRWIVHPPSFIFYYCHGGCGLPTLQDLPLPVPGVPPTPFQPLSLVPGAQACCAalPGTMRPLRVRTTSDGGYSFKYEMVPNLL TQHCAC- >UniRef50_Q6VZT3(179-282:282) CNPV064 TGF-beta-like protein n=1 Tax=Canarypox virus RepID=Q6VZT3_CNPV E=2e-10 s/c=0.64 id=24% cov=98% --CTTKQKYLDLKYLDMDDTIIAPRGITFKYCSGYCDiNSMKNFYSNSLYGILaMKFISLKAINSNFKRCCYPESMENISILYIDPNGN-IKKGELVNST ISKCVCK >UniRef50_B0YLF5(198-305:307) Gonadal transforming growth factor beta-like protein n=1 Tax=Crassostrea gigas RepID=B0YLF5_CRAGI E=9e-10 s/c=0.60 id=24% cov=95% --CNVVPWTVDFAELGWDKFISFPLTYNANACEGKCAQSRNCVSAMNkpinmlkNYEILRRLYaYCPDVSLLDHSCCRPSKYGSQGIVFRGASGSLFFIV -VSQMRVLEC--- >UniRef50_Q6T265(292-403:404) Antivin/lefty n=6 Tax=Echinoida RepID=Q6T265_PARLI E=5e-18 s/c=0.82 id=26% cov=99% -RCCRRRKYVDFRDLSWtSRWIIEPAGFEAFDCYGPCHNPRSRHIRdvfrlPFFGASSSGSSIFGAGSGGHRTCGV-SRSSSLPMMYLSEtpsGTVELKV EEIPNMIVEDCGCQ >UniRef50_P03971(462-560:560) Muellerian-inhibiting factor n=10 Tax=Theria RepID=MIS_HUMAN E=1e-17 s/c=0.92 id=24% cov=94% --CALRELSVDLRA---ERSVLIPETYQANNCQGVCGWPQSDRNPRYgNHVVLLLKMQVRGAALARPPCCVPTAYAGKLLISLSEER--ISAHHVPNMVA TECGCR >UniRef50_D2DEC7(317-422:423) Transforming growth factor Tgh-2a n=2 Tax=Trichinella spiralis RepID=D2DEC7_TRISP E=2e-18 s/c=0.89 id=25% cov=97% --CCRRRFRISFDELGWGDWVLAPKQFHSYYCIGRCTgfgGEFPTDGGADGFAFYSELMNLYRSteKNYMKPCCSPIQFAPLTIAIW-QGPNEQATQTLD NVVVTKCGC- >UniRef50_UPI000175FE99(138-231:232) PREDICTED: similar to neurturin n=2 Tax=Danio rerio RepID=UPI000175FE99 E=4e-10 s/c=0.70 id=19% cov=90% --CSLRKLVVTVSQLGIA--FVSDETIAFHYCSGECDASRKNYDFVLEAMKKKGLLRKN--KARHRPCCRPTAYEE-DFLFLD---NSFQYKTIHEFSAK ACGC- >UniRef50_C8CIE5(59-151:162) Gonadal soma-derived growth factor (Fragment) n=2 Tax=Percomorpha RepID=C8CIE5_SCOJP E=8e-08 s/c=0.62 id=23% cov=90% --CCSMTSEIFMKDLGWDSWVVHPASLTIVQCA-LCNPEVSPVQCPSSHTNVLDP-----DSQVQMPCCQPTSQEMVPIVYVDQFSTLVISSVQ---LTR SCSC- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * S 1 3048 * * * * * * * * * * * * * * 1231 1142 * * * 1 0 * * * * * * 4856 0 0 H 2 5330 * 3205 4056 * * 3375 * * * * 3188 4257 3764 1421 5096 3801 * * * 2 0 * * * * * * 5413 0 0 C 3 * 0 * * * * * * * * * * * * * * * * * * 3 0 * * * * * * 6504 0 0 Q 4 4931 1009 * 4389 * 6971 3206 * 5318 * * 4613 * 3776 3564 4413 5609 6026 * * 4 0 * * * * * * 6504 0 0 K 5 6697 * * * * * * 4337 3441 2118 * * * * 1023 5245 5005 3862 * * 5 18 6370 * 0 * * * 6504 1000 0 T 6 6241 * * 3525 5375 4810 3072 5882 4006 6398 5932 5441 * 3433 1920 6244 4826 3838 * 3114 6 0 * * * * * * 6504 0 0 S 7 4813 * 2733 2926 * 5330 5845 6335 4838 5507 * 4400 3171 3878 4058 2345 3960 * * 5420 7 0 * * * * * * 6513 0 0 L 8 * * * * 2012 * 6946 5849 4045 1358 3478 6251 * 5349 * 4587 6587 4382 5067 5736 8 0 * * * * * * 6513 0 0 R 9 * * 4417 3191 4615 * 6609 5558 5435 5574 5785 4162 5133 5581 3504 4825 3653 3980 6692 1609 9 0 * * * * * * 6516 0 0 V 10 5556 * * * 6489 * * 1694 * 4907 6255 * * * * * * 708 * * 10 0 * * * * * * 6516 0 0 N 11 4779 * 1280 6297 5949 * 6346 * 4201 6451 * 3119 * 6426 * 1937 4414 6609 * * 11 0 * * * * * * 6516 0 0 F 12 * * * * 341 * * * * 2756 5178 * * * * * * 4838 * * 12 51 4860 * 0 * * * 6516 1728 0 E 13 3507 * 4024 3162 * 6039 * * 2189 6346 * 4575 * 2838 2691 3323 5893 4690 * * 13 17 * 6425 * * * * 6516 0 0 D 14 3736 * 1449 1839 * 6568 4961 6437 3578 5473 * * * 4057 * 5321 6242 * * 5615 14 53 * 4789 * * * 0 6505 0 1000 I 15 5421 * 5608 * 4294 * * 1803 * 1033 3595 * * * * * * 5101 * 5807 15 0 * * * * * 0 6456 0 2025 G 16 * * 5608 5383 * 463 5764 6580 3737 * * 5926 4492 5586 6670 6127 * * 5622 * 16 22 * 6026 * * * 0 6487 0 2025 W 17 * * * * 4538 4864 * * * 3401 4273 * * * 6213 * * * 417 6170 17 271 5203 2796 0 * 674 1422 6444 1414 2491 D 18 3848 5690 1652 4237 5580 3019 6233 6512 6305 * * 2671 6440 6888 4573 3020 * * * 5919 18 326 4496 2665 825 1200 102 3876 6346 1945 4606 S 19 * * 1537 3234 * 4139 4495 * 3274 * * 3443 * 5268 3516 3473 6579 * * 4687 19 32 5519 * 526 1710 0 * 6402 1544 4262 W 20 * * * 4959 2763 * 5085 6691 * * * * * * * 3562 5659 * 623 5171 20 22 * 6041 * * * * 6539 0 0 I 21 * * * * 6376 * * 581 * * 6025 * * * * * * 1718 * * 21 0 * * * * * 0 6527 0 1000 I 22 6144 * 6562 * 6719 * 5444 1497 * 1644 4978 * * * 6385 6244 * 2316 * 6545 22 0 * * * * 0 * 6527 0 1000 A 23 1547 * * 3018 4414 6528 3735 6437 5294 4345 6766 * * 3565 * 2729 * 6820 * 4017 23 0 * * * * * * 6553 0 0 P 24 5618 * 6054 * 5897 * * * * * * * 77 * * * * * * * 24 0 * * * * * * 6553 0 0 K 25 4112 * * 3078 * * 5583 * 1846 4180 * 7050 2857 5182 2610 3303 5691 6392 * * 25 24 * 5897 * * * * 6553 0 0 E 26 5579 * 6650 4239 * 1410 6338 6233 4358 5644 * 6792 * 5079 3871 2775 2768 4455 * * 26 26 5787 * 0 * * 0 6517 1000 1000 Y 27 5442 * * * 1500 * * 3748 * 4226 * * * * * 5560 5886 4602 * 1264 27 0 * * * * * 0 6517 0 1000 E 28 5126 * 2345 3038 6614 * 3486 5361 5680 5116 6121 2341 * 3765 6535 4207 3760 5886 6747 5038 28 0 * * * * * 0 6517 0 1000 A 29 760 * * * 3312 5560 * 3951 * 3888 6757 * 5017 * * 5059 4742 6443 * 4784 29 0 * * * * * 0 6517 0 1000 Y 30 7077 * * * 3415 3779 4650 * 5684 6352 * 1763 * 6258 3413 4059 4643 5236 * 2143 30 0 * * * * 0 * 6563 0 1000 E 31 6342 * 6228 4561 2948 * 6029 * 6821 5383 4003 3928 * 3778 4137 * 7068 4581 * 1161 31 0 * * * * * * 6885 0 0 C 32 * 34 * * * * * * * * * * * * * 5434 * * * * 32 0 * * * * * * 6885 0 0 K 33 3516 * 6865 3623 * 4205 3926 3743 3484 5858 4768 5472 * 4100 3462 2592 5034 3714 * 4622 33 31 * 5578 * * * * 6885 0 0 G 34 * * 5994 * * 42 * * * * * * * * * 6282 * * * * 34 0 * * * * 0 * 6843 0 1330 G 35 3344 * 4625 3351 * 3814 5215 4945 3495 5166 * 6561 4966 4485 3688 2668 2944 4875 6309 5869 35 23 6012 * 0 * * * 6885 1000 0 C 36 * 34 * * * * * * * * * * * * * * * * 5434 * 36 108 7025 3958 0 * * * 6885 1000 0 F 37 4091 * 4921 4549 5692 3893 5225 * 3802 5905 * 4845 1744 4095 5190 3014 3896 5040 * 5425 37 239 4433 3235 853 1163 * 0 6996 2116 3233 F 38 4111 6113 6839 5493 2666 3897 3447 5856 4618 4030 5816 3738 5384 5249 3502 3918 4796 4568 6186 3798 38 45 * 5010 * * 2847 216 6811 0 4763 P 39 4644 * 5875 3795 5176 6282 3508 4857 5208 3105 6413 6112 1338 5790 6208 3614 6440 5791 * * 39 63 * 4549 * * * 0 6821 0 4533 L 40 3740 * 5124 * 4404 6045 5322 3614 * 1964 4118 5423 5533 5221 3317 3883 5329 3798 4468 4977 40 25 5852 * 1000 1000 1006 994 6763 1251 4845 A 41 3575 * 3613 5722 5332 3473 4955 6437 5705 4818 * 3603 3500 4616 4438 2079 4114 5696 * 5017 41 62 * 4577 * * 1830 477 6806 0 3967 D 42 4912 6077 4384 4420 5458 3961 3739 * 5712 * 4921 2510 3182 3909 4482 3207 3452 5978 6264 5811 42 55 * 4745 * * 1942 435 6766 0 4076 D 43 6890 * 2844 5474 4357 5139 2482 6517 4150 4306 5230 4372 5780 5566 3472 5278 3994 4037 * 3293 43 109 6747 3980 1585 585 2939 202 6912 1000 4102 V 44 5229 * 3298 * 4506 4398 6653 3932 5218 2553 3614 3848 * 4489 5462 4232 3951 4027 * 3185 44 57 * 4689 * * 1274 770 6853 0 4632 T 45 3502 6020 4914 * 4938 4368 5660 4932 4841 3651 6621 2117 3434 5280 4091 3283 4609 6637 * 4517 45 46 5723 6338 2322 322 1936 437 6726 1000 4232 P 46 1717 * 5527 6386 4747 4860 5053 * 5370 3771 4967 3532 3168 6805 4826 3197 4132 5447 * * 46 0 * * * * 2403 302 6903 0 3650 T 47 * * 5473 * 5002 5388 5229 6052 * 4196 4460 3331 3829 6383 * 2352 1675 5768 * 3805 47 77 4962 5663 1904 448 1826 478 6930 2115 3488 K 48 5681 * * 6329 3708 4095 3873 * 3070 3481 6450 1829 6507 4594 5522 4476 4909 4039 * 4322 48 104 6731 4055 0 * * 0 6947 1000 3295 H 49 5808 * * 4915 4853 4228 670 * * 6001 * * 5159 * * 5467 4893 * * 2916 49 25 5837 * 1279 766 2640 252 6892 1461 4344 A 50 1033 * * 5387 5719 4257 6403 * 5069 4949 6298 6458 6682 6324 * 2609 3334 5474 * 6620 50 0 * * * * 2166 364 6900 0 4142 I 51 4986 * 6636 * 3849 5711 4274 2174 5269 3043 4414 5121 * 4651 5520 4061 3278 2883 * 6207 51 38 * 5267 * * 3073 183 6943 0 3566 V 52 4550 * * * 6194 * * 2224 4980 2072 3779 * 5273 6675 6265 4806 5236 2044 * 4884 52 57 4685 * 411 2012 * 0 6757 2241 3769 Q 53 5716 * 6402 * 7093 6397 4221 6873 3622 2503 3340 * 5273 1673 4083 4628 4111 5802 * 5900 53 12 6938 * 1585 585 2376 309 6757 1000 3769 T 54 3362 * 4498 5114 6419 3719 5307 6445 4022 4637 * 3059 6804 4814 4631 2327 2643 7006 * 4986 54 18 6334 * 0 * * 0 6755 1000 3740 L 55 5371 * * 6014 4653 5566 5940 2965 6391 1428 5089 6748 4121 5019 3864 3308 5533 4656 * 6189 55 60 * 4625 * * 2038 403 6755 0 3740 V 56 4061 * * 5762 4594 6255 6336 2841 6337 1997 2811 6398 * 5564 5213 3983 * 3141 * 3771 56 138 4840 4157 1676 542 * 0 6711 2139 3866 H 57 3962 * * 6347 5584 * 2328 5041 3377 4302 * 3065 4810 3237 3798 3993 4520 6243 5774 4177 57 56 4712 * 1036 965 1754 508 6723 1641 4568 L 58 4520 5330 6503 4101 3980 4997 4084 5981 3832 2677 5895 6411 3680 3609 3809 3345 4568 5391 * 4575 58 30 5600 * 1030 970 3042 187 6780 1541 3837 K 59 5335 * 5483 6804 6861 3385 4750 5015 3381 3093 4195 3599 5341 5663 2886 3532 5815 3809 * 3924 59 63 5903 5256 2075 391 * 0 6795 1532 3764 F 60 4546 * 3318 4869 6892 3500 7009 5974 3498 4062 5633 2905 4818 4436 3614 3083 5071 5791 5508 4348 60 75 5280 5339 1528 614 1345 722 6789 1888 3991 P 61 4483 * 4291 4269 * 4922 5340 4572 3972 4007 * 5090 1790 3809 4222 3393 5422 3948 * * 61 68 4799 6598 694 1389 516 1735 6875 1715 3165 T 62 3275 * 3112 5037 4432 5052 4203 * 3233 4814 * 3207 4184 4790 5787 2571 4890 4810 5995 7155 62 12 6968 * 0 * 813 1215 6982 1000 2152 K 63 2986 * 5054 5257 * 3784 4796 4867 3366 3943 * 3100 5031 3478 3147 3706 4646 5272 6639 6592 63 42 7314 5484 1585 585 * 0 6857 1000 1433 V 64 3781 * * 5022 5758 3757 5462 3340 * 3839 * 3425 6865 4546 3995 3423 4551 2077 * 4936 64 57 5551 5856 0 * 1666 546 6809 1180 2411 S 65 3401 * 5050 4371 5789 4692 4192 4526 5774 4257 4487 * 1702 4370 5011 3109 5278 5139 * * 65 158 3413 6689 1724 520 2126 375 6802 4129 2929 K 66 3803 6211 * 3887 * 3333 4802 6498 2773 5179 4883 5759 3528 3613 2952 3392 4343 6860 * 5377 66 44 5049 * 972 1029 2253 340 6944 1897 2594 A 67 3336 * * * * 6745 * 5962 * 3539 6396 6418 933 4354 4894 3276 4824 6353 6778 * 67 45 6712 5575 2000 415 526 1710 6945 1000 2392 C 68 * 187 * * * * 6711 * 5252 * * * * 6725 5428 4228 * * * * 68 18 6329 * 2585 263 0 * 6683 1000 2040 C 69 * 51 * * * 5368 * * * * * * * * * * 6578 * * * 69 0 * * * * * * 6885 0 0 V 70 2467 * 5434 * * 6878 4647 4498 4860 * * * * 6266 3245 3811 3283 1590 * 4499 70 70 5443 5368 1000 1000 * * 6885 1127 0 P 71 4131 * * * * * * 6140 * * * * 127 * * 6278 * * * * 71 0 * * * * 0 * 6850 0 1408 T 72 4434 * 5953 4840 * 4897 7141 3624 3612 5534 * 6012 * 5379 5764 2227 1624 3780 * 6821 72 15 6621 * 1000 1000 * * 6885 1000 0 K 73 3562 * 5402 2811 * * 5178 * 2338 5600 * 6465 * 3830 2311 3006 4065 5629 * 6012 73 0 * * * * * * 6885 0 0 L 74 * * * * 3931 * 5265 * * 1712 2385 * * 6266 4218 6228 3936 * * 1908 74 0 * * * * * * 6885 0 0 S 75 3850 * 3244 2670 6811 3911 5259 5407 3956 6920 * 6592 * 6169 2837 2120 4077 * * 5905 75 42 6578 5781 0 * * * 6885 1000 0 P 76 3167 * 2887 6945 * 4281 6039 6623 6767 * 5417 4865 1836 * * 1749 6420 * * 6350 76 21 * 6121 * * * 0 6725 0 1500 I 77 * * * * 4507 * 5989 2383 6479 1278 3156 * * 4072 * * 6957 2891 * 6570 77 0 * * * * 652 1459 6697 0 1838 S 78 4259 6381 3846 4647 * 6396 5779 5485 4285 4292 6599 4210 3710 6229 4998 1812 2811 4610 * 5796 78 0 * * * * * 0 6698 0 1000 V 79 4913 * * * 3439 * * 1926 * 2289 2429 * * * * * * 2368 * 5192 79 14 6725 * 0 * 0 * 6698 1000 1000 L 80 5555 * * * 6853 * 6161 2246 6529 1327 3126 * * * 4354 5155 4017 3823 6395 * 80 38 * 5249 * * * * 6687 0 0 Y 81 * * 5068 5462 3140 * 3969 4294 6660 5134 6757 * * 6444 5648 5065 5416 3397 6722 1051 81 45 * 5026 * * * 0 6692 0 1892 K 82 5972 * * * 3061 * 5855 3236 4634 2543 3993 * 6113 4838 4478 4651 4933 2911 6465 2690 82 129 6617 3731 2000 415 2117 378 6616 1000 2878 D 83 6323 * 1233 2932 6416 4456 6820 5428 * 5238 * 2792 * * 7021 3431 4441 5358 * * 83 58 7044 4984 1000 1000 698 1382 6470 1000 4357 D 84 3475 * 3503 2209 6522 4613 4192 * 4046 6910 * 3405 4338 3022 4622 3118 * 7044 * * 84 34 6220 6708 1585 585 1226 805 6501 1000 3443 M 85 5051 * 2465 2852 4889 3563 5030 * 6282 4684 6999 2367 5418 6328 5461 3224 4585 5894 * 5403 85 76 * 4287 * * 0 * 6571 0 2720 G 86 * * 3429 4119 * 1082 4301 * 4935 * * 2979 6393 4661 5637 4992 4882 * 5051 * 86 182 5592 3350 1000 1000 292 2449 6936 1511 2610 V 87 * * 4469 5021 5214 * * 6576 3990 4517 * 2388 6081 3621 2890 3636 2998 3517 * 3941 87 117 * 3686 * * 599 1557 6613 0 3861 P 88 5293 * 4219 3560 6485 5427 6562 3296 3513 3685 5603 3637 6887 4131 6474 3868 3303 2839 7030 5112 88 11 * 7030 * * 183 3067 6614 0 3821 T 89 4216 * 6642 6722 4061 * 4751 1894 3800 3261 * * 5343 4189 * 5143 3875 2262 * * 89 116 * 3692 * * * 0 6684 0 1426 L 90 6404 * * 4323 4762 * * 2785 2863 2433 4489 6269 * 3588 3615 4111 6265 3179 * 5058 90 103 6657 4090 0 * 1458 653 6483 1000 3843 K 91 5632 * * * 5710 6595 * 4414 1801 4547 6584 5273 * 4942 5700 5058 2204 2966 5773 3437 91 377 5756 2243 0 * 226 2785 6464 1079 4471 Y 92 3649 * 5031 3440 6426 5072 3306 6284 3071 6723 5647 5360 * 4256 2817 3727 3829 3351 * 4992 92 155 6777 3431 0 * 785 1253 6884 1000 4762 H 93 * * 3361 2595 * * 3778 5973 3682 5363 6234 3848 4349 5582 3591 3881 2334 4838 * 6746 93 91 5244 4843 0 * 237 2725 6571 1551 4876 Y 94 * * * * 3563 * 5507 3048 * 1536 4853 * * 5400 * * * 2486 4570 2749 94 22 * 6031 * * 607 1541 6670 0 2883 E 95 6130 * 3567 2815 * 6963 5303 * 4430 6699 * 3556 1592 3405 4196 3768 6342 5769 * * 95 36 * 5361 * * 1494 633 6646 0 2208 G 96 * * 1773 3732 * 3478 * * 3364 * * 1361 * 5100 5230 * * * * * 96 0 * * * * 766 1279 6632 0 2358 M 97 * * * * 3869 * * 3982 * 2520 781 * * * * 5761 5349 3858 * * 97 0 * * * * 722 1345 6634 0 1330 S 98 5313 * * 4511 * * * 2541 4597 3851 4561 * * 5226 3669 3285 4737 1471 * * 98 0 * * * * * 0 6675 0 1000 V 99 1744 * * * * * * 3684 * 6384 * * 4335 * * * 4376 961 * * 99 0 * * * * 0 * 6675 0 1000 A 100 3491 * 3871 1890 * 5557 * 6167 2948 3183 * 5073 * 4934 3649 4974 3579 4627 * * 100 0 * * * * * * 6687 0 0 E 101 4060 * 3668 1712 * 4181 4260 * 2938 * * 6553 * 5090 3932 2564 4517 * * * 101 0 * * * * * * 6711 0 0 C 102 * 0 * * * * * * * * * * * * * * * * * * 102 0 * * * * * * 6720 0 0 G 103 2571 * 5165 4983 * 1003 5144 * 4808 * * * * 6562 6645 3014 4745 5170 * * 103 0 * * * * * * 6669 0 0 C 104 * 0 * * * * * * * * * * * * * * * * * * 104 0 * * * * * * 6699 0 0 R 105 * * * * * * * * 3765 * * * * 2922 332 * * * * * 105 0 * * 0 * * * 4641 0 0 //