HHsearch 1.5 NAME c9dprA_ FAM FILE c9dprA_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9dprA_.a3m DATE Sat Mar 8 12:42:14 2025 LENG 106 match states, 106 columns in multiple alignment FILT 101 out of 348 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 6.5 EVD 0.4005 -1.0544 SEQ >ss_pred CCCCEEEEEEEEHHHCCCCCEEECCCCEECEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCEE EEEECC >ss_conf 9865321016868671987338317863010334245876666777642467889974126334677860550145304999858998999997178389 431119 >Consensus gxxCcrxxxxVxFxxlGWxxwIixPxxxxaxyCxGxCxxxxxxxxxxxxhaxixxxxxxxxxxxxxxpCCxPxxxxxlxilyxdxxgxxxxxxxxxnmvv xxCgCr >c9dprA_ GSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISVLYKDDMGVPTLKYHYEGMSV AECGCR >UniRef50_P05111(261-365:366) Inhibin alpha chain n=26 Tax=Theria RepID=INHA_HUMAN E=1e-17 s/c=0.86 id=21% cov=98% --NCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVPGAPPTPAQPYSLLPGAQPCCAalPGTMRPLHVRTTSDGGYSFKYETVPNL LTQHCAC- >UniRef50_Q6VZT3(179-282:282) CNPV064 TGF-beta-like protein n=1 Tax=Canarypox virus RepID=Q6VZT3_CNPV E=4e-11 s/c=0.66 id=24% cov=97% ---CTTKQKYLDLKYLDMDDTIIAPRGITFKYCSGYCDiNSMKNFYSNSLYGILaMKFISLKAINSNFKRCCYPESMENISILYIDPNGN-IKKGELVNS TISKCVCK >UniRef50_UPI0000E46956(396-491:511) PREDICTED: similar to myostatin 1 n=2 Tax=Strongylocentrotus purpuratus RepID=UPI0000E46956 E=2e-14 s/c=0.83 id=25% cov=91% ---CCRRTMDVSFSDLGWS-WMVAPRRLTTSVCIGSCLAP-----NMTFESFMVNLMQgHGRPSSRDERRCRPSRTDHFDALVINEDGDIQMMR-LPDFI VRECAC- >UniRef50_C8CIE5(58-151:162) Gonadal soma-derived growth factor (Fragment) n=2 Tax=Percomorpha RepID=C8CIE5_SCOJP E=2e-08 s/c=0.64 id=23% cov=90% --KCCSMTSEIFMKDLGWDSWVVHPASLTIVQCA-LCNPEVSPVQCPSSHTNVLDP-----DSQVQMPCCQPTSQEMVPIVYVDQFSTLVISSVQ---LT RSCSC- >UniRef50_P03971(462-560:560) Muellerian-inhibiting factor n=10 Tax=Theria RepID=MIS_HUMAN E=6e-18 s/c=0.93 id=24% cov=93% ---CALRELSVDLRA---ERSVLIPETYQANNCQGVCGWPQSDRNPRYgNHVVLLLKMQVRGAALARPPCCVPTAYAGKLLISLSEE--RISAHHVPNMV ATECGCR >UniRef50_UPI000175FE99(138-231:232) PREDICTED: similar to neurturin n=2 Tax=Danio rerio RepID=UPI000175FE99 E=4e-10 s/c=0.70 id=19% cov=90% ---CSLRKLVVTVSQLGIA--FVSDETIAFHYCSGECDASRKNYDFVLEAMKKKGLLRKN--KARHRPCCRPTAYEE-DFLFLD---NSFQYKTIHEFSA KACGC- >UniRef50_B0YLF5(198-305:307) Gonadal transforming growth factor beta-like protein n=1 Tax=Crassostrea gigas RepID=B0YLF5_CRAGI E=4e-10 s/c=0.61 id=24% cov=94% ---CNVVPWTVDFAELGWDKFISFPLTYNANACEGKCAQSRNCVSAMNkpinmlkNYEILRRLYaYCPDVSLLDHSCCRPSKYGSQGIVFRGASGSLFFI V-VSQMRVLEC--- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * G 1 * * * * * 0 * * * * * * * * * * * * * * 1 0 * * * * * * 4068 0 0 S 2 * * * 5020 * 4391 5182 * 4978 * * 2628 5477 * 3169 1423 2367 * * * 2 0 * * * * * * 5266 0 0 H 3 4989 5338 3965 4423 * * 3936 5980 3198 5768 * 3673 3836 3088 1882 5605 4291 * * 6005 3 42 5121 * 608 1539 * * 5719 1545 0 C 4 * 0 * * * * * * * * * * * * * * * * * * 4 0 * * * * * * 6415 0 0 Q 5 4845 1076 5564 4236 * 5605 3443 * 5320 6221 * 4603 * 4362 3426 4406 5640 5980 * * 5 0 * * * * * * 6415 0 0 K 6 6810 * * * * * * 5138 3345 2121 6704 * 6533 6401 1060 5240 5029 3934 * * 6 0 * * * * * * 6415 0 0 T 7 6240 * * 3643 5396 5213 3489 5911 3844 6392 5921 4914 * 3317 1977 6211 4714 3805 * 2819 7 0 * * * * * * 6415 0 0 S 8 4802 * 2969 2911 * 5277 4640 6285 5558 5438 * 5045 2772 4014 3816 2456 3966 * * 5347 8 17 6401 * 2807 222 * * 6415 1000 0 L 9 * * * * 2021 * 5741 5898 3973 1240 3773 6211 * 6001 * 4622 6718 4734 5048 6514 9 0 * * * * * * 6415 0 0 R 10 * * 4424 3401 4568 * 4850 6235 5393 5507 * 4228 5669 5365 3845 4788 3121 3691 5613 1704 10 0 * * * * * * 6421 0 0 V 11 6390 * * * 6502 * * 1822 * 4276 5256 * * * * * * 698 * * 11 0 * * * * * * 6421 0 0 N 12 4838 * 1349 6235 5933 6755 6303 * 4627 6340 6723 2905 * 6277 * 1941 4606 6533 * * 12 0 * * * * * * 6421 0 0 F 13 * * * * 286 * * * * 2945 5122 * * * * * * 5564 * * 13 46 4991 * 0 * * * 6421 1688 0 E 14 3531 * 4183 3047 * 5990 6546 * 2091 6303 * 4439 * 3071 2882 3421 5397 4450 * * 14 0 * * * * * * 6421 0 0 D 15 3935 * 1424 1820 * 6622 4935 6335 3490 6252 * * * 3954 * 5369 6280 * * 5660 15 52 * 4809 * * * * 6421 0 0 I 16 5385 * 5622 * 4283 * * 1814 * 1018 3499 * * * * * * 5578 * 5882 16 22 * 6024 * * * 0 6372 0 1731 G 17 * * 5646 6374 * 437 5608 6495 3356 * * 6825 4787 6639 * 5336 * * 5614 * 17 43 * 5100 * * * 0 6387 0 1929 W 18 * * * * 4879 4499 * * * 3729 4258 * * * 6104 * * * 385 6174 18 342 4666 2542 0 * 501 1769 6329 1769 2765 D 19 4748 4780 1815 3656 4991 3167 4912 * 6226 * * 2603 6322 6688 4537 2985 * * * 5855 19 237 6196 2856 0 * 179 3099 6254 1000 4609 S 20 * * 1531 3242 * 4544 4381 * 3306 * * 3205 * 4782 3563 3794 6569 * * 4496 20 31 * 5557 * * 116 3689 6326 0 4061 W 21 * * * * 2578 * 5667 6604 * * * * * * * 3976 5680 * 534 5118 21 0 * * * * 1029 972 6396 0 1530 I 22 * * * * 6304 * * 574 * 6433 6099 * * * * * * 1788 * * 22 0 * * * * 0 * 6417 0 1000 I 23 6140 * 6541 5764 6663 * 5641 1494 * 1688 4977 * * * 6570 6260 * 2353 * 6594 23 0 * * * * * * 6460 0 0 A 24 1507 * * 3021 4328 * 3781 6390 5730 5381 6730 * * 3730 6284 2725 * 5922 * 3604 24 0 * * * * * * 6460 0 0 P 25 5527 * 5764 * * * * * * * * * 59 * * * * * * * 25 0 * * * * * * 6460 0 0 K 26 4405 * 6816 3011 * * 5514 * 1687 4458 * 6466 2947 4905 2677 3410 5869 * * * 26 0 * * * * * * 6465 0 0 E 27 6202 * 5711 4945 * 1478 6388 6500 4321 5731 * 5733 * 4974 3431 2732 2856 4262 * * 27 27 5730 * 0 * * * 6465 1000 0 Y 28 5401 * * * 1313 * * 3777 * 4264 * * * * * 5530 5968 5077 * 1390 28 11 7011 * 0 * * * 6465 1000 0 E 29 4831 * 2374 2989 * * 3442 4764 7020 4783 5318 2261 * 4236 5159 4703 3807 5968 6738 5432 29 0 * * * * * * 6465 0 0 A 30 857 * * * 3156 5530 * 3922 * 3893 5852 * 4548 * * 5045 4190 * * 4806 30 0 * * * * * * 6465 0 0 Y 31 7040 * * * 3415 3605 4739 * 5123 6315 * 1726 * 6535 3831 4083 4658 5228 * 2126 31 0 * * * * * * 6519 0 0 E 32 6342 * 6175 4879 3218 * 6191 * 6758 5395 4225 3866 * 3700 4299 * 6867 4620 * 1039 32 0 * * * * * * 6777 0 0 C 33 * 36 * * * * * * * * * * * * * 5345 * * * * 33 0 * * * * * * 6777 0 0 K 34 3419 * 6154 3680 * 3914 3694 4037 3609 5748 5425 5448 * 4215 3292 2708 4702 3740 * 4612 34 32 * 5498 * * * * 6777 0 0 G 35 * * 5959 * * 45 * * * * * * * * * 6121 * * * * 35 0 * * * * 0 * 6878 0 1336 G 36 4057 * 3934 3176 * 3812 5586 5317 3353 5081 * 5764 5438 4546 3541 2573 3120 4818 6266 5828 36 23 6008 * 0 * * * 6777 1000 0 C 37 * 36 * * * * * * * * * * * * * * * * 5345 * 37 106 7053 3983 0 * * * 6777 1000 0 F 38 3763 * 4861 4790 6816 3686 6047 6163 3823 4941 7165 4841 1794 4313 4811 3001 4118 6751 * 5109 38 220 4628 3308 994 1006 * 0 6873 1772 3026 F 39 4066 6052 5712 5474 2396 4402 3713 4975 4551 3520 6781 3698 5345 5273 3851 4333 4724 5246 6180 3738 39 85 * 4126 * * 2790 225 6642 0 4628 P 40 4740 * 6449 3754 5112 6143 3140 4122 4728 3593 * 6097 1316 * 4937 3848 6241 6537 * * 40 78 * 4242 * * 3030 188 6618 0 4640 L 41 4091 * 6276 * 3677 6037 6099 3507 * 1846 4221 4924 * 5179 3326 4267 5167 3237 6486 4523 41 64 5861 5267 1658 550 1264 777 6922 1463 4879 A 42 3468 * 3697 * 6611 2943 4452 5630 4793 4477 * 4043 3463 4923 4573 2336 3999 5277 * 4938 42 52 6802 5229 1000 1000 2224 348 6822 1000 4337 D 43 4850 5458 4887 4343 6370 3928 3850 * 4685 * 4319 2741 3111 4030 4532 2781 3747 6587 6262 6602 43 44 * 5064 * * 1697 532 6797 0 4214 D 44 6850 * 3002 6510 5847 4563 2577 6409 4327 4051 4963 3744 5870 4958 3553 4637 4478 4022 6260 3245 44 106 6345 4097 1585 585 1534 611 6869 1000 4009 V 45 4219 * 3515 * 4591 4400 6691 4274 5192 2462 3987 3594 7027 5210 * 4058 3827 3793 * 3102 45 37 * 5315 * * 1880 457 6836 0 4196 T 46 3784 5989 4278 * 4732 4025 6884 4779 4121 3793 * 2144 3101 5241 4395 3437 5047 6434 * 4809 46 41 5697 6846 2322 322 1943 435 6874 1000 3916 P 47 1775 * 5520 * 4272 4468 5643 * 4857 4092 5044 3467 3051 6684 4749 2944 4667 5774 * * 47 17 6455 * 1585 585 1702 530 6855 1000 3539 T 48 7063 * 5497 * 4974 6326 4859 * 6399 4019 4476 4247 3823 6369 * 2112 1645 5815 * 3857 48 84 4961 5366 1884 456 2514 278 6865 2127 3152 K 49 5159 * * 6225 3870 4425 3519 * 3366 3790 6609 1753 6487 4369 4757 4015 4895 4432 * 4575 49 97 5783 4410 0 * 2922 204 6847 1678 3311 H 50 5889 * * 5025 4458 4795 646 * * 6416 * * 5245 * * 5451 4594 5908 * 3146 50 13 6822 * 1000 1000 2294 329 6781 1000 4075 A 51 1025 * * 5479 5522 4277 * 5937 4790 5215 6244 * * 6176 * 2553 3265 5490 * 6657 51 12 * 6930 * * 1868 462 6817 0 3721 I 52 4689 * 6671 6849 3919 5639 4186 1861 5081 2998 4957 5092 * 6701 6224 3869 3572 3263 * 5043 52 38 * 5248 * * 2873 212 6868 0 3157 V 53 4962 * 7208 * * 5992 * 2062 4926 2217 3747 * 5331 6754 * 4698 5861 1943 * 4897 53 38 5261 * 349 2219 * 0 6676 1531 3625 Q 54 5677 * * * 7098 6461 4427 4956 3799 2868 3299 7208 4839 1695 3871 4585 3882 5957 * 5150 54 12 6934 * 1585 585 3126 176 6676 1000 3625 T 55 3355 * 4169 4611 * 3696 6214 * 3686 4989 6002 3128 6470 5853 5259 2144 2646 6855 * 5233 55 27 5753 * 415 1999 2705 240 6682 1538 3487 L 56 5428 * * 5881 4621 6635 6029 3087 5598 1421 5077 6878 4163 4826 3738 3311 5075 4401 * * 56 49 * 4893 * * * 0 6682 0 3360 V 57 3870 * * 4981 4279 6210 6281 3076 6238 2095 2501 * * 6586 5169 4143 6906 3144 * 3983 57 166 4542 3933 1582 586 3269 158 6643 2575 3682 H 58 4220 * * 6430 4844 * 2449 4460 3601 4658 * 2689 4798 3643 3549 3762 4442 * 5167 4465 58 101 4199 6281 780 1260 2128 375 6670 2412 4490 L 59 4492 5180 6585 4015 4233 4819 4123 4975 3802 2746 5166 5502 4011 3807 3967 3507 4468 4949 * 4497 59 36 5359 * 1089 916 1911 446 6741 1558 4088 K 60 5173 * 6156 5831 5791 3417 5227 4344 3458 2908 4823 3388 5197 5553 2985 3582 6748 3710 * 4212 60 25 * 5884 * * * 0 6715 0 3646 F 61 3678 * 3213 4759 6767 3404 4834 5914 3873 4417 6808 2905 5515 4345 3534 3213 6918 5743 5424 4352 61 64 6808 4860 2000 415 2194 356 6712 1000 3699 P 62 4438 * 4085 4016 * 5506 4813 4361 3392 4262 * 4593 1701 5058 5177 3339 5960 4109 * * 62 85 4125 * 1065 938 672 1425 6479 2451 3776 T 63 3851 * 3275 5181 4902 4038 4715 * 3219 4724 * 3265 4428 5651 5932 2315 4030 4390 5287 * 63 54 6799 5186 0 * 1750 509 6876 1000 2287 K 64 3227 * 4695 5161 * 3376 6583 4798 2777 3786 * 3374 5023 3761 3401 3346 4355 6341 * 6601 64 22 * 6044 * * 1324 736 6581 0 3073 V 65 3986 * * 5023 5788 3640 4996 3227 * 3728 * 3267 6846 4078 3944 3845 4236 2315 * 4885 65 68 6569 4820 0 * 1229 803 6739 1000 3043 G 66 4105 * 4741 4523 5851 3913 4567 4149 5079 4162 3980 * 1517 4724 4435 4013 5614 6153 * * 66 127 3738 6743 1484 638 1180 840 6831 3520 3278 K 67 4155 6082 * 3646 * 3255 4287 6584 2776 5291 5042 6667 3665 3581 2905 3499 4285 6683 * 5287 67 36 5341 * 1013 987 2154 367 6879 1893 2689 A 68 3520 * * * * * * 5141 * 4015 6363 6247 834 4388 4972 3412 4810 5208 * * 68 30 * 5617 * * 505 1759 6881 0 2389 C 69 * 174 * * * * * * 5217 * * * * 6523 5374 4270 * * * * 69 19 6233 * 2585 263 0 * 6739 1000 2022 C 70 * 53 * * * 5326 * * * * * * * * * * 6455 * * * 70 0 * * * * * * 6777 0 0 V 71 2302 * 5345 * * 5994 4642 4740 4799 * * * * 6229 3387 3615 3659 1591 * 4576 71 70 5461 5326 1000 1000 * * 6777 1129 0 P 72 3895 * * * * * * 6141 * * * * 143 * * 6235 * * * * 72 0 * * * * 0 * 6896 0 1408 T 73 4481 * 4446 4768 * 4935 * 3592 3807 4945 * 5412 * 5423 5312 2454 1722 3532 * 6792 73 15 6616 * 1000 1000 * * 6777 1000 0 K 74 3691 * 5833 2952 * * 5574 * 2226 6445 * 6443 * 4076 2396 2884 3337 5720 * 6008 74 0 * * * * * * 6777 0 0 L 75 * * * * 3592 * 5736 * * 1785 2179 * * 6229 3961 6175 4428 * * 2003 75 0 * * * * * * 6777 0 0 S 76 4108 * 3389 2734 5945 3702 5684 5460 3757 * * 6975 * 6145 2892 2095 3792 * * 5380 76 45 6455 5690 0 * * * 6777 1000 0 P 77 3121 * 2896 6974 * 4440 6154 6540 6836 * 5434 4461 1858 6788 * 1922 4932 * * 6261 77 26 * 5834 * * * 0 6599 0 1500 I 78 * * * * 4554 * 6007 2388 6397 1170 3124 * * 4238 * * * 3114 * 6466 78 0 * * * * 652 1459 6558 0 1838 S 79 4481 6328 4028 4590 * 6399 6508 6658 4038 4229 5629 3884 3897 5903 5004 1855 2634 4896 * 5723 79 0 * * * * * 0 6604 0 1000 V 80 4926 * * * 3635 * * 1864 * 2488 2472 * * * * * * 2157 * 5103 80 14 6690 * 0 * 0 * 6604 1000 1000 L 81 5581 * * * 6791 * 6159 2320 6466 1279 3265 * * * 4375 5069 3978 3742 6369 * 81 28 * 5724 * * * * 6594 0 0 Y 82 * * 5881 5440 2900 * 3904 4530 5568 5757 6616 7208 * * 6479 5080 5413 3635 6715 985 82 45 * 5027 * * * 0 6493 0 1648 K 83 5978 * * * 2955 * 6661 3342 5094 2466 3643 * 6035 4868 4427 4645 4896 3476 6483 2428 83 150 * 3345 * * 1904 448 6420 0 2665 D 84 * * 1091 3126 6326 4437 6559 * * 4676 * 2734 * * 6824 3494 4807 5383 * * 84 61 6994 4886 1000 1000 751 1302 6367 1000 4088 D 85 3569 * 3793 2071 5601 4956 3850 * 3660 * * 3406 4063 3219 4886 3319 * 6844 * * 85 55 6173 5402 1585 585 747 1306 6417 1000 3628 M 86 5477 * 2416 2952 4825 3360 4494 * 6276 4300 6871 2518 5419 6235 4974 3230 5887 5296 * 5665 86 117 * 3678 * * 0 * 6504 0 3217 G 87 * * 3319 3925 * 1040 4068 * 6239 * * 2869 6403 5764 6887 4570 4725 * 5706 * 87 189 5477 3314 1000 1000 505 1759 6521 1458 3221 V 88 * * 4757 5656 5989 * 6822 6483 3173 4512 6667 2401 6002 3749 2637 3530 3091 4767 * 4007 88 119 * 3662 * * 617 1523 6465 0 4023 P 89 5615 * 4508 3676 6680 * * 3085 3639 3980 5501 3249 5674 4776 5343 4003 3243 2657 6904 4530 89 28 * 5680 * * 194 2991 6451 0 3848 T 90 4150 * 6484 5675 4119 * 6741 1815 4603 2923 * * 5327 4178 6783 6487 4141 2172 * 6641 90 68 * 4440 * * 1432 668 6471 0 2007 L 91 6458 * * 4179 4786 * 6623 2710 2418 2575 4014 6210 * 4079 3881 4043 * 3759 * 4565 91 85 * 4124 * * 1259 780 6450 0 3201 K 92 5577 * * * 5905 6640 6630 4203 1890 4934 5290 5761 * 4796 4732 4028 2357 3068 6612 3609 92 259 * 2605 * * 286 2474 6471 0 4080 Y 93 3624 * 4700 3270 6614 5522 3939 5672 3243 6688 * 5334 * 4326 2721 3751 3686 3025 * 4523 93 217 5732 3052 0 * 672 1425 6423 1431 4889 H 94 * * 3162 2591 5612 * 3802 4817 4364 6085 6234 3663 4309 4650 3563 3490 2847 4781 * * 94 127 4434 4725 0 * 292 2450 6431 1823 4938 Y 95 * * * * 3777 * 5387 2801 * 1655 5575 * * 5312 * * * 2499 4572 2498 95 24 * 5933 * * 248 2660 6466 0 3030 E 96 7029 * 4080 2826 * * 5285 * 3928 * * 3354 1491 3362 4174 3717 * 5750 * * 96 36 * 5324 * * 1014 986 6544 0 1631 G 97 6894 * 1887 3737 * 3458 * * 3717 * * 1276 * 5016 5215 * 6896 * * * 97 0 * * * * 1193 830 6536 0 1891 M 98 6580 * * * 3644 * * 3704 * 2814 772 * * * * 5742 6068 3809 * * 98 0 * * * * 724 1341 6539 0 1336 S 99 6801 * * 4638 * * * 2653 4616 3787 4298 * * 4881 3701 3332 4716 1398 * * 99 0 * * * * * 0 6582 0 1000 V 100 1771 * * * * * * 3495 * * * * 4217 * * * 4353 955 * * 100 0 * * * * 0 * 6582 0 1000 A 101 3808 * 3662 1923 * 6361 * 6122 3015 3201 * 4991 * 4596 3461 4476 3667 4659 * * 101 0 * * * * * * 6594 0 0 E 102 4349 * 3764 1639 * 4299 4011 * 3233 * * 6530 * 5078 3955 2733 3609 * * * 102 0 * * * * * * 6512 0 0 C 103 * 0 * * * * * * * * * * * * * * * * * * 103 0 * * * * * * 6520 0 0 G 104 2571 * 5500 5605 * 880 5519 * 5381 * * 6863 * 6639 6474 3064 5005 5701 * * 104 0 * * * * * * 6494 0 0 C 105 * 0 * * * * * * * * * * * * * * * * * * 105 0 * * * * * * 6490 0 0 R 106 * * * * * * * * 3142 * * * * 2603 470 * * * * * 106 0 * * 0 * * * 4599 0 0 //