HHsearch 1.5 NAME c9d8jC_ FAM FILE c9d8jC_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9d8jC_.a3m DATE Sat Nov 1 09:33:12 2025 LENG 1112 match states, 1112 columns in multiple alignment FILT 22 out of 24 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 3.2 EVD 0.3156 -10.0877 SEQ >ss_pred CCCCHHHHHCCCCEEEECCCCCEEECCCEEEECEEEEECEEEEEEECCCEEEEEEECCCCCEECCCCEEEEECCEEEECCCCCCEEEEEEEECCCCCCEE EEEEECCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCEEEEECCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCC CCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCEEEEEEECCCCCHHHHEEEECCCCCCCCEEECCC CEEEEEEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEEECCCCCEECCCEECCCCCCCCCHHHHCCCEEEEEEEEEEEECCCCEEEECCCCCCC CEEEECCCCCCCCCCCCCHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEECCCEEEEEEEEEECCC CCCCCCCCCCCCCEEEECCEEEEEECCEEEEEEEEECEEEEECCEEEEEECCCCEEEEEECCCCCEEEEEECCCCCEEEEEECCCCCCCEEEEECCCCCC EEEEECCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEECCCEEEECCCEEEEEEEEEEEEE CCCEEEEECCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCEEEEE EEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE EEEECCCCCEEEEEEEEECCCCEEEEEEEEEEEECCCEEEEEEEEEEEECCEEEEEECCCCCCCCCCCCCEEEEEEEEEEEEECCHHHCCCCCCCCCCHH HHHHHHHHHHCC >ss_conf 9661343310110010000001011232103010466110463220551332255245554010572147506435420247650367876212367359 9999624102655532011214898523257777630235202320454011210472567412443421221024687149549999658852013555 6655311489844044120223334665321476554333554310023551223069999715753787875265414442111024456887210467 5555325899804776557704330777765433432114654103610101031112110156463441122000134203663155112212676764 2042026765433333310000245334565523788504777766643310011220000133455667651000378887513420004799973058 8854445653232255421144785435889999601002764458997158825788753788379998425345067761345664025764044321 2564101100111000002467643221025641345775025213100441133236652244421113455320035504744521578888899864 4625996120450883799999999989989999999885555257899999865420134565545762202205788776642045654310001100 2332344337626767888988888999998741101100232111318989987514021328889988999999999999999988899999999999 9997448999999999751101357789999998754444101456556679999999999999999999999999999989975121101544687689 9970249981899999754687599998655665483543420068987898999531312641676455699941026999655333664377766868 889998642059 >Consensus xxxxxxxxxxxtxxxxxxxxxxxxxxdxxxxxxxxxlxxxxxxxxxxxxxxxxxxxgtxxxxxfxxxxxpxxdgxxxxxxxxxxxxxgxxfgxtxxxxxx xxxxxxnxxnxxxxvcxxxxcxxpxxxxxxxxxxxxxxxxxxxxxxxxnxtxxxvxxxxxxxxxxxxxxxxxxxxfxfxxxxgxxxxyxxxxxxxxxxxx xxxxxxxxxxxlxxgxxxxxxxxxxxxxxsxxxxxxxxxxxxxxxxxxxvxxLxxxxxLlxydxnGxitxavdCxxxxxxxLkCxxxsfxxxdGfYxxsx xxvxxxxtfvxxpxxxxxcxxxxxxxxtxxpsxxxwxrxxxxncnxnxsxxxsxxxxxxfkCxxVxxxxlxxxcfssvxxdxfxixxxxxxxlxxgxxxx xxxxnykxxdxxxxcxxxxxxxxxxxxxxxxxxxxxxxxxxgxxxxxxxxixxxxxxxxxkxxsxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxixxxxx xxpxtxxgxxxxsxixxdxCvxYnIYGxtGxGVixxxnsxxxxgxxxxxdxsgxLxgfknxtTgxiyxVxPCxxxxxxxvxxgxxxsxxxaxlxxxxxcx xxxxxxxxxxxxxxxxxxxtxxxxxxxxxgcxixaxxxxxxxnCxxpxxxxxcxxxxxxxxxxxxxxtxxxxxxxxxxxxnIxIPtnFtlsvtxEylQxx xxkvsIDCaxYVCngnxrCxxLLxQYgsfCxxIexaLxxxaxledxxxxxxxxxxxxxxxxxxxxxxgxxNfsxiLpxxsxxxxRSaIEDLLFxKVvtDL vCAQyYNGImVLPgVvdaexmamYTasLxGgmaxggxTagxxsAxaIPFaxavQaRlNylalttxVLxeNQkilAnsFNxAignIqxgfxtvsxALxKIQ dVVNxqxxALxxLxxQLsxNFgAISSSixdIyxRLDxleAdaQVDRLItGRLxALnafVtQxLxxxxevraSrxLAqqKINECVKSQSxRygFCGNGtHi xSlxqxAPnGixFlHxxlvPtxxvxVxaxxGlCvxxxxxvpkxgxfvxxxxxwxiTxRxxyxPrxiTxsdxvxixsCxVxyxnxtxxxlxxxxpdxxDfn xelxexfxNxts >c9d8jC_ CVMPLFNLITTTQSYTNSFTRGVYYPDKVFRSSVLHLTQDLFLPFFSNVTWFHAISGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQ SLLIVNNATNVFIKVCEFQFCNDPFLDVYHKNNKSWMESESGVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPIIGRDFP QGFSALEPLVDLPIGINITRFQTLLALNRSYLTPGDSSSGWTAGAADYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSN FRVQPTESIVRFPNVTNLCPFHEVFNATTFASVYAWNRTRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIKGNEVSQIAPGQTGN IADYNYKLPDDFTGCVIAWNSNKLDSKHSGNYDYWYRSLRKSKLKPFERDISTEIYQAGNKPCKGKGPNCYFPLQSYGFRPTYGVGHQPYRVVVLSFELL HAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTKSNKKFLPFQQFGRDIVDTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCT EVSVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEYVNNSYECDIPIGAGICASYQTSQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVS MTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLKRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKYFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLDL ICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLFSTASALGKLQ DVVNHNAQALNTLVKQLSSKFGAISSVLNDILSRLDPPEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHL MSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFLTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQLELDSFK EELDKYFKNHTS >UniRef50_Q02385(38-1264:1376) Spike protein S2 n=160 Tax=Coronavirinae RepID=SPIKE_CVMJC E=0 s/c=0.86 id=35% cov=94% ----------STEAVDVSKGLGTYYVlDRVYLNATLLLTG--YYPVDGSNYRNLALTGTNtlSLTWFKPPFLsEFNDGIFAkvqnlktntptgATSYFPT IVIGSLFGNT--SYTVVLEPYNNI--IMASVCTYTICQLPYTPCKPNTNGNRvigfwhTDVKPPICLLKRNFTFN-VNAPWLY--------------FHF YQQGGTFYAYYADKP----------SATTFLFSVYIGDILTQYFVLPFIC----TPTAGSTLLP----LYWVTPLLKRQYLFNFNEKGVITSAVDCASSY ISEIKCKTQSLLPSTGVYDLSGYTVQPVGVVYRRVPNLPDCKIEEWLTAKSVPSPLNWERRTFQNCNFNLSSLLRYVQAESLSCNNIDASKVYGMCFGSV SVDKFAIPRSRQIDLQIGNSGFLQTANYKIDTAATSCQLyyslpknnvtinnynpsSWNRRYgfndagvfGKSKHDVAYAQQCFIVRPSYCPCAQPDIVS AC-TSQTKPMSAYCPTGtihrecslwngphlrsarvgsgtytcectckPNPFDTYDLRcgqikTIVNVGDHCEGLGVLEDKCGNsDPHKGCscahdsfiG WSHDTCLVNDhsqifanillnginsgttcstdlqlpntevatgVCVRYDLYGITGQGVFKEVKADYYNsWQALLYDVNGNLNGFRDLTTNKTYTIRSCYS GRVSAAY--HKEAPEPALLYRNINCSYVFTNNISREENPL--------NYFDSYLGCVVNADNRPDEAlpNCDLRMGAGLCVDYSKSRRarrsvSTGYRL TTFEPYMPMLVNDSVqsvgglyemQIPTNFTIGHHEEFIQIRAPKVTIDCAAFVCGDNAACRQQLVEYGSFCDNVNAILNEVNNLLDNMQLQVASALMQg vtISSRLPDGISGpidDINFSPLLGcigstcaedgnGPSAMRGRSAIEDLLFDKVKLsdvgfveaynnctggqevrDLLCVQSFNGIKVLPPVLSESQIS GYTAGATAAAMFPPWTAAAG----VPFSLNVQYRINGLGVTMNVLSENQKMIASAFNNALGAIQEGFDATNSALGKIQSVVNANAEALNNLLNQLSNRFG AISASLQEILTRLDRVEAKAQIDRLINGRLTALNAYISKQLSDSTLIKFSAAQAIEKVNECVKSQTTRINFCGNGNHILSLVQNAPYGLCFIHFSYVPTS FKTANVSPGLCISGdRGLAPKAGYFVQDNGEWKFTGSNYYYPEPITDKNSVVMISCAVNYTKAPEVFLNNSIPNLPDFKEELDKWFKNQTS >UniRef50_B2BW33(473-1343:1472) Spike protein n=1 Tax=Beluga Whale coronavirus SW1 RepID=B2BW33_9GAMC E=0 s/c=0.86 id=27% cov=71% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------------------------------------FISTLNYTTALVTFD-KGNVRSVIDCnSEKPFDRLRCDLQTDVVSDGFYPVN ikTNEAKENTTFIDVPATLANLTL-EVFVSSPEQSPA---------CV-----------IKSYKC--VDTRYFYISDYS--------------------- ---YSCAENGIPNDAAGAA------YCRGVLDQINNYGVRGMDfKGKCPFAGSKVNSgltfdkICFGVYEQGCqSDKACRFGFYFDNVQFSqYGNKLYYK PQDLGFIDYQFGTLFKNSL---VQSNIIQEGCHDYDIYGYKGTGVVKPFSdySYLQTGGLIMLDSGGFPSLFRYN--FALYEVTQC-----------TRE VAQLAVASNNAIGYYLPKQVTIDGVNASTSCNTTGAFKYCYYDDVIhVGRDVSNVTINVCNPslmMENSHCINIQGNFMVNEPAITFnsTQYQPLLGVSG DVQLPRTLMLHTTTEFIQTHSPKIVIDCTKYVCGSSERCRRILVKYGGFCESIMRLLNGVNMADDvsvTDFLDNFNSFDNISVSLqnlnaSFGQFEGYGF QKFLPksfdfDGSDPRdARSTIEDILFDKVTTvglgtvdadydkctkglsvaDLVCAQYYNGIMVLPGVADAEKMAMYTGALVGGMVLG----GITSAAA IPFATQIQARVNYLALTQNAIQENQKIIVQQFNKAIDSMTsafqsvnEGFSAVSSAITEVQNAVNAQSQALTKLLGQLNYNFGATTSSIKELYERLAKLE ADVQVDRLINGRLTALSAFVAARQVEAAKVASQRVLAAEKINECVKSTSNRYGFCGNGAHIISFPQNAPNGMLFVHFSLVPNETITVKGIIGLCLNNSiG IVPAkdRGMFIQcsngtycpefensfneskNGNVTFpfaITSREQYNPRQITTGDIQMLTSCNSGYTHIEWSQLPLVAPPYDDFDKEFDKLYE---- >UniRef50_B3FHU5(115-1066:1226) Spike n=17 Tax=Coronavirinae RepID=B3FHU5_CVTKE E=0 s/c=0.77 id=29% cov=70% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------DTTINKLRCAYQQFNFSTGFYDID- -------TFVPVTSNITYLPYPDLKDNTGQEVCDFYVALKGDHVIYNQSCVDSKYPFFKLKCNNTYSWDNDKLCIlgSEIYVPGYNVYTNTQHSYAGTIP NYPTCSSKGLSLENIYNNIGFNRFCVTKLLTT------------------RDISSITQYTCVYVVSVEG------FDSYNQGIVYSYVGVNFDFGTAMYS VKTAPMQF--------IYTEQCHKYNIYNIRGVGqilnVTGKDNTTLVDGGLVITSGSG-LLAFRNN--GSLFSVQPCRTVSTQAVI----VNGSFVGLF VPASCwlaDQFNLGNHTEYVD----GGCLISNKTISRKRRSTNAVYTGECTGLFAAMGTSCIYSNGTVLNRTLPQPSVQTSvQPLLGVVANVSIPKELTL AVTTEYLQTRYQKVTIDCAKYVCGDSTRCRTLLQQYGSFCQSVNAILSGVNENEDNGLLQYAEAINTGYTLNFTGYNvsnlGGFDLSLVLPKNltlAQNQ GRSTIEDLLFDKVVTlgvsevdqnydkciasrggsftnlaDLTCAQFYNGVMVLPGVVDPGLMAVYTGSLIGGMALGGITA----AASIPFATQIQARVN YLALTQSVLLDNQNLIANSFNKALKGIQsaldtvsqgfvevaRGFESVTVALNKVQDVVNTHSDILNKLMAQLSVNFGAVSSSLNEIYLKLDQINADAQV DRLITGRLTALSTYVASLQLAAYKADQSRRLALQKVEECVKSQSMRYGFCGNGSHVLTIPQSAPNGIFFIHYTYQPTSYVTIEAVPGLCVTtpsgKYGVM PKtgSGIIFRQNDTFFVTSTQLYEPKLLSYSEVVNLTSCEANYYNVSESE-TPFQPALPNFDDEFNDIF----- >UniRef50_Q65984(376-1325:1453) Spike glycoprotein n=344 Tax=Alphacoronavirus RepID=SPIKE_CVCAK E=0 s/c=0.76 id=27% cov=70% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------SHINNIKCSQLTANLQNGFYPVAS SEVGLVnKSVVLLPSFYSHTSVNITIDLGMKRSGYG-QPIASTLSNITLPMQDNNTDVYCIRSNRFS-VYFHSTCKSSLWDDVFNSDCTDVLYA----TA VIKTGTCPFSFDKLNNYLTFNKFCLSLNPVGANCKFDVAARTRTNE----QVVRSLYVIYEEG----------------------------------DNI VGVPSDNSGLHDLSVLHLDSCTDYNIYGITGVGIIRQTNSTLLSGLYYT-SLSGDLLGFKNVSDGVIYSVTPCDVSAHAAVIDGAIVGAMTSINSELLGL THWTT-------TPNFYYYSIYNYTNERTRGTAIDSNDVDCE-----PIITYSNIGVCKNGALVFINVTHSDGDVQPISTGNVTIPTNFTISVQVEYIQV YTTPVSIDCSRYVCNGNPRCNKLLTQYVSACQTIEQALAMGARLENMEIDSMLFVSENALKLASVEAFNSTetldpiykewpniggswlgGLKDILPShN SKRKYRSAIEDLLFDKVVTsglgtvdedykrctggydiaDLVCAQYYNGIMVLPGVANDDKMAMYTASLAGGITLGSL---GGGAVSIPFAIAVQARLNY VALQTDVLNKNQQILANAFNQAIGNITQAFGKVNDAihqtsqglatvakvLAKVQDVVNTQGQALSHLTLQLQNNFQAISSSISDIYNRLDELSADAQVD RLITGRLTALNAFVSQTLTRQAEVRASRQLAKDKVNECVRSQSQRFGFCGNGTHLFSLANAAPNGMIFFHTVLLPTAYETVTAWSGICASDgdrtFGLVV KDvqlTLFRNLDDKFYLTPRTMYQPIVATSSDFVQIEGCDVLFVNATVIDLPSIIPDYIDINQTVQDILEN--- >UniRef50_A3EXG6(19-1160:1274) Spike protein S2 n=4 Tax=Rousettus bat coronavirus HKU9 RepID=SPIKE_BCHK9 E=0 s/c=0.91 id=34% cov=96% CFNPRFTLtpLNHTLNYTSikAKVSNVLLPDPYIAYSGQTLRQNLFMADMSNTILYPVTppaNGANGGFIYNTSIIPVSAGLFvntwmyrqpASSRAYCQ EPFGVAFGDTFENDRIAILIMapdnlgswsavapRNQTNIYLLVCsNATLCINPGFNRWGPAG-SFIAPDALV-DHSNSC---FVNNTFSVNISTSRISL A----FLFK--DGDLLIYHSGwlpTSNFEHGFSRGSHPMTYFMSLPVGGNLPRAQFFQSIVRSnAIDKGDGMC--TNFDVNLHVAHLINRDLLVSYFNNG SVANAADCADSAAEELYCVTGSFDPPTGVYPLSRYRAQ-VAGFVRVTQRGSYCtPPYSVLQDPPQPVV--WRRYMLYDCVFDFTVVVDSLPTHQLQCYGV SPRRLASMCYGSVTLDVMRINETHLNNLFNRVPDTFSLYNYALPDNFYGCLHAFYLNSTAP---------YAVANRFPIKPGGRQSNSA----------- -------FIDTVINAAHYSPFSYVYGLAVITLKPAAGSKLVCPVANDTVVITDRCVQYNLYGYTGTGVLSKNTSLVIPdGKVFTASSTGTIIGVSINST- -TYSIMPCVTVPVSV---GYHPNFERALLFNGLSCSQRSRAV-TEPVSVLWSASATAQDAFDTPSGCVVNVELRNTTIvnTCAMPIGNSLCfinGSIATA NADSLPRLQLVNYDPLYdNSTATpmtpvywVKVPTNFTLSATEEYIQTTAPKITIDCARYLCGDSSRCLNVLLHYGTFCNDINKALSRVSTILDSALLSL VKelSINTRDEVTTFSFDGDYNFTGLMgclgPNCGATTYRSAFSDLLYDKVRItdpgfmqsyqkcidsqwggsirDLLCTQTYNGIAVLPPIVSPAMQAL YTSLLVGAVASSGYTFGITSAGVIPFATQLQFRLNGIGVTTQVLVENQKLIASSFNNALVNIQKGFTETSIALSKMQDVINQHAAQLHTLVVQLGNSFGA ISSSINEIFSRLEGLAANAEVDRLINGRMMVLNTYVTQLLIQASEAKAQNALAAQKISECVKAQSLRNDFCGNGTHVLSIPQLAPNGVLFIHYAYTPTEY AFVQTSAGLCHNGTGYAPRQGMFVlpNNTNMWHFTTMQFYNPVNISASNTQVLTSCSVNYTSVNYTVLEPSVPGDYDFQKEFDKFYKNLST >UniRef50_A3EXD0(235-1245:1352) Spike protein S2 n=12 Tax=root RepID=SPIKE_BCHK5 E=0 s/c=0.82 id=36% cov=77% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------AAFYIYKLHPLTYLLNFDVEGYITKAVDCGYDDLAQLQCSYESFEVETGVYSVSS FEASPRGEFIE-QATTQECDFTPMLTGTP-PPIYNFKRLVFTNCNYNLTKLLSLFQVSEFSCHQVSPSSLATGCYSSLTVDYFAYSTDMSSYLQPGSAGA IVQFNYKQDFSNPTCRVLATVPQNLTTITKPSNYAYLTECYKTSAYGKNYLYNAPGA--YTPClslasrgfsTKYQSHSDGELTTTG--YIYPVTGNLQM AFIISVQYGTDTNSVCPMqalRNDTSIEdkLDVCVEYSLHGITGRGVFHNCTSVGLRNQRFVYDTFDNLVGYHSDN-GNYYCVRPCVSVPVSVIYD--KA SNSHATLFGSVACSHVTTMMSQfSRMTKTNLLARTTPGPLQTTVGCAMGFINSSMVVdECQLPLGQSLCAippttssrvRRATSGASDVFQIATLNFTSP ltlAPINSTgfvVAVPTNFTFGVTQEFIETTIQKITVDCKQYVCNGFKKCEDLLKEYGQFCSKINQALHGANLRQDESIANLFSSIKtQNTQPLQAGLNG DFNLTMLqIPQvtTGERKYRSTIEDLLFNKVTIadpgymqgydecmqqgpqsarDLICAQYVAGYKVLPPLYDPYMEAAYTSSLLGSIAGASWTAGLSSF AAIPFAQSIFYRLNGVGITQQVLSENQKIIANKFNQALGAMQTGFTTTNLAFNKVQDAVNANAMALSKLAAELSNTFGAISSSISDILARLDTVEQEAQI DRLINGRLTSLNAFVAQQLVRTEAAARSAQLAQDKVNECVKSQSKRNGFCGTGTHIVSFAINAPNGLYFFHVGYQPTSHVNATAAYGLCNTenpQKCIAP IDGYFVLNQTTstvadsdqqWYYTGSSFFHPEPITEANSKYV-SMDVKFENLTNRLPPPLLSNstDLDFKEELEEFFKNVSS >UniRef50_A6N252(130-904:1035) Spike protein n=3 Tax=Guangxi coronaviridae RepID=A6N252_9NIDO E=0 s/c=1.01 id=28% cov=66% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------CDKSVVDSIACQRSSHQVEDGFYSDPK SAVRaRQRTIVTLPKLPEL--------------------------------------------EVVQLNISAHMDFGEARLDSVTINGNTSYCV--TKPY FRLETNFLCRGCTMSLRTDTCSFDLSAVNNGmSFSQFCLSTESGACEM-----------------------------KIIVTYVWNYLLRQRLYVTAVEG QTHTGTTAVHATDTSSVVTDVCTDYTIYGVSGTGIIKPSDLLLHNGIAFT-SPTGELYAFKNITTGKTLQVLPCETPSQLIVI-------------NNTV VGAITSSNSTEN-NRFTTTIVTPTFFYSTNA----------TTFNCTKPVLSYGPISVCSDGAIAGtSTLQNTRPSIVSLYDGEVEIPSAFSLSVQTEYL QVQAEQVIVDCPQYVCNGNSRCLQLLAQYTSACSNIEAALHSSAQLDSREIINMFQTSTQSLQLANITNFkGDYNFSSIL--TTRVGGRSAIEDLLFNKV VTsglgtvdqdykscsrdmaiaDLVCSQYYNGIMVLPGVVDAEKMAMYTGSLTGAMVFGGLTAAAAIPFA----TAVQARLNYVALQTNVLQENQKILAE SFNQAVGNIslalssvndaiqqtSEALNTVAIAIKKIQTVVNQQGEALSHLTAQLSNNFQAISTSIQDIYNRLEEVEANQQVDRLITGRLAALNAYVTQL LNQMSQIRQSRLLAQQKXNECVKSQSSRYGFCGNGTHIFSLTQAAPNGIFFMHAVLVPNKFTRVNASAGICVDntrGYSLQPQLILYQFNN-SWRVTPRN MYEPRLPRQADFIQLTDCSVTFYNTTAANLPNIIPDVIDVNQTVSDIIDN--- >UniRef50_P05135(208-1040:1163) Spike protein S2 n=1237 Tax=Avian coronavirus RepID=SPIKE_IBV6 E=0 s/c=0.90 id=29% cov=71% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -----------------------------------------------------------LAYFVNGTAQDVILCDGSPTGLLACQYNTGNFSDGFYPFTN SSlVKEKFIVYRESSV----------------------NTTLELTNFTFSNVSNATPNTG----GVQTIQLYQTI-------------TAQSGYYNLNFS FLSSFIYKASDYMYGSYHPSCKFRLETINNGLwFNSLSVSLGYGPIQGGCKQ---SVFANRATCCYAYSYNGP-SLCKGVYRGELTKSFECGLLVFVTKT DGSRIQTRNEPftltqHNYNNITLDRCVEYNIYGRVGQGFITNVTNYAINY-NYLADG-----GMAILDTSGAIDIF-VVQGEYGLNYYKVNPCEDV--- ------NQQFVVSGGKLVGILTSRNETGSQPLENQFYIKIINGTRrsrrsitGNVTNCPYVTYGKFCIKPDGSISTIVPKELEHFVAPLLNVTENVLIPD SFNLTVTDEYIQTRMDKVQINCLQYVCGNSLECRKLFQQYGPVCDNILSVVNSVGQKEDMELLYFYSSTKPSGFNTPVLSNvstGEFNISLLLTPPSSAS GRSFIEDLLFTSVESvglptddaykkctagplgflkDLACAREYNGLLVLPPIITAEMQTLYTSSLVASMAFGGIT----SAGAIPFATQLQARINHLGI TQSLLFKNQEKIAASFNKAIGHMQEGFRSTSLALQQIQDVVNKQSSILTETMASLNKNFGAISSVLQDIYQQLDSIQADAQVDRIITGRLSSLSVLASAK QAEYYRVSQQRELATQKINECVKSQSIRYSFCGNGRHVLTIPQNAPNGIVFIHFTYTPESFVNVTAIVGFCVNPanasqYAIVPAngRGIFIQVNGSYYI TARDMYMPRDITAGDIVTLTSCQANYVSVNKTVITTfVDNDDFDFDDELSKWWND--- >UniRef50_A8JP00(219-1017:1128) Spike glycoprotein n=3 Tax=Rhinolophus bat coronavirus HKU2 RepID=A8JP00_9ALPC E=0 s/c=0.83 id=29% cov=68% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- --------------------------------------------------------------DQSGAVTRYSYCADGFVNGLQCKLRLFDIPPGVY--SN SEVEYPVALYTVVHNMSVCPqrPESYCGSNYCP----FKRVVFSNCVVNYTSWTSGL-----------------------------LRDYQHLVLPNGKF NPFTECNglNRIVDD---CVTGFVLRVGRGTA----------------------VNRTVITPYLKPNECFG----WSWNDYqDSIYDWWIADFVSTGAFV CEKNPDAPRTG------------VCITYTIEKVTFQGVLYESNFTFAQYYNVLY-FGSQLKYVRIL--GKVYEVAPCFEASYDVLF---RSSSSFGLLYR SFDCNQlrISASRFAERLLPSHNGTATA-------LGCLFNATYAPNDTmvNCTNPLGDGFCADLLSN--VVVRRMTFEKHDTTYVAPVTIerftELPLD HQLVLTEQFLQTTMPKFSISCETYICDVSKACKNLLFRYGGFCQKIEADIRGAGVLLDSDVSGLYSTIAAKTSSIMPTTD-RFNVSQfFLPKVQSTSErf esRSVIEDLLFSKIETtgpgfygdyynckknaiqDLTCAQYHNGILVIPPVMDAETLGMY-----GGIAAASLTLGIfgGQAGITTWSLAMAGRLNALGV VQNALVDDVNKLANGFNQLTASVSKLALTTSSALQAIQAVVNQNAAQVESLVSGITENFGAISTNFKVISQRLDKLEADVQMDRLINGRMNVLQLFVTNY KLKIAELRNTHRYVQSLINECVYAQSLRNGFCGQGLHVLSLMQNAPSGIMFFHYSLIPNNTIIVKTTPGLCESDelgsKCIVAKDGVLVSaNLSYWQWSP RNLYKPENLTFAN-VIAVSRGANYTTLNRTFDIPELNNTFPIEEEFREYFQNMSS # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * C 1 * 0 * * * * * * * * * * * * * * * * * * 1 0 * * * * * * 1545 0 0 V 2 * * * * 1065 * * * * * * * * * * * * 938 * * 2 0 * * * * * * 1545 0 0 M 3 * * * * * * * * * * 938 1065 * * * * * * * * 3 0 * * * * * * 1545 0 0 P 4 * * * * * * * * * * * * 0 * * * * * * * 4 0 * * * * * * 1545 0 0 L 5 * * * * * * * * * 938 * * * * 1065 * * * * * 5 0 * * * * * * 1545 0 0 F 6 * * * * 0 * * * * * * * * * * * * * * * 6 0 * * * * * * 1545 0 0 N 7 * * * * * * * * * * * 938 * * * * 1065 * * * 7 0 * * * * * * 1545 0 0 L 8 * * * * * * * * * 0 * * * * * * * * * * 8 938 1065 * 1000 1000 * * 1545 1000 0 I 9 * * * * * * * 938 * 1065 * * * * * * * * * * 9 0 * * * * * * 1545 0 0 T 10 * * * * * * * * * * * 1065 * * * * 938 * * * 10 0 * * * * * * 1545 0 0 T 11 * * * * * * 1601 * * * * * * * * 1622 1533 * * * 11 0 * * * * * * 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* 49 0 * * * * * * 2214 0 0 T 50 * * * * 2379 * * 2045 * * * * * * * * 1399 * * 2424 50 0 * * * * * * 2214 0 0 W 51 * * * * * 2394 * * * 2045 * * * * 1402 * * * 2405 * 51 0 * * * * * * 2214 0 0 F 52 * * * * 1399 * * * * * * 1402 * * * * * * * 2045 52 0 * * * * * * 2214 0 0 H 53 * * * * * * 1399 * * 2424 2379 * 2045 * * * * * * * 53 0 * * * * * * 2214 0 0 A 54 818 * * * * * * * * * * * * * * * 2394 2045 * * 54 0 * * * * * * 2214 0 0 I 55 * * * * * * * 1399 * 1402 * * * * * * 2045 * * * 55 400 2045 * 1585 585 * * 2214 1000 0 S 56 * * * * * * * * 2379 * * 1209 * * * 2405 2424 * * * 56 0 * * * * * * 2214 0 0 G 57 * * * * * 305 2394 * * * * * * * * * * * * * 57 0 * * * * * * 2214 0 0 T 58 2045 * * * * * * * * * * * * * * * 400 * * * 58 305 * 2394 * * * * 2214 0 0 N 59 * * * * * * * * * * * 356 * * 2193 * * * * * 59 818 1209 * 1000 1000 * 0 2109 1251 1000 G 60 * * * * * 818 * * * * * * * * * 1209 * * * * 60 0 * * * * * 0 2109 0 1000 T 61 * * * * * 1848 * * * 2225 * * * * * * 976 * * * 61 0 * 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* * * * * * * * * * * 2045 1386 1415 * * * 99 0 * * * * * * 2214 0 0 Q 100 * * * * * * * 1202 * * * * * 1399 * * * 2424 * * 100 0 * * * * * * 2214 0 0 S 101 2045 * * * * * * * * * * * * * * 1399 * 1402 * * 101 0 * * * * * * 2214 0 0 L 102 * * * * * * * 2045 * 1415 * * * * * * * 1386 * * 102 0 * * * * * * 2214 0 0 L 103 * * * 1402 * * * 2394 * 1214 * * * * * * * * * * 103 0 * * * * * * 2214 0 0 I 104 * * * * * * * 686 * * * * 1402 * * * * * * * 104 0 * * * * * * 2214 0 0 V 105 * * * * * * 2379 2394 * * 2045 * * * * * * 2405 * 2424 105 400 2045 * 3700 115 * * 2214 1000 0 N 106 * * * * * * * * * * * 823 * * 2045 * 2379 * * * 106 0 * * * * * * 2214 0 0 N 107 * * * * * * * * * * * 308 * * * 2379 * * * * 107 0 * * * * * * 2214 0 0 A 108 2405 * * * * * * 2424 * 2379 * * * 2045 * 2394 * * * * 108 297 * 2424 * * * * 2214 0 0 T 109 * * * * * * * 1831 * * * * * * * * 476 * * * 109 0 * * * * * 0 2085 0 1000 N 110 * * * * * * * * * * * 0 * * * * * * * * 110 476 1831 * 2585 263 0 * 2085 1000 1000 V 111 * * * * * * * 1222 * 2379 * * * * * * * 1399 * * 111 0 * * * * * * 2214 0 0 F 112 * * * * 2405 * * * * * 2424 * * 2379 * * * 2394 * 2045 112 0 * * * * * * 2214 0 0 I 113 2424 * * * * * * 807 * 2045 * * * * * * * * * * 113 0 * * * * * * 2214 0 0 K 114 * * * * * * * * 2405 2045 * * * * 2394 1402 * * * * 114 0 * * * * * * 2214 0 0 V 115 2394 * * * * * * * * * * * * * * * * 305 * * 115 0 * * * * * * 2214 0 0 C 116 * 0 * * * * * * * * * * * * * * * * * * 116 400 2045 * 0 * * * 2214 1000 0 E 117 * * * 2405 * * * * * * * 1209 * 2379 * * 2424 * * * 117 0 * * * * * * 2214 0 0 F 118 2045 * * * 1399 * * * * * * * * * * * * * * 1402 118 0 * * * * * * 2214 0 0 Q 119 * * * 2394 * * * * * * * * * 2405 * * 688 * * * 119 0 * * * * * * 2214 0 0 F 120 * * * * 2405 * * 2424 * 1209 2379 * * * * * * * * * 120 0 * * * * * * 2214 0 0 C 121 * 0 * * * * * * * * * * * * * * * * * * 121 0 * * * * * * 2214 0 0 N 122 * * 2394 2379 * * * 2045 * * * 2405 * 2424 * * * * * * 122 0 * * * * * * 2214 0 0 D 123 * * 2405 * * * * * * 2424 * 1209 * * * * * * * 2379 123 0 * * * * * * 2214 0 0 P 124 * * * * * * * * * * * * 0 * * * * * * * 124 0 * * * * * * 2214 0 0 F 125 * * * * 1399 2045 2379 * * * * * * * * * * * * 2424 125 0 * * * * * * 2214 0 0 L 126 * * * * 1209 * * * * 2405 * * * * * * 1402 * * * 126 0 * * * * * * 2214 0 0 D 127 2394 * 2405 * * * * 2379 * * * 2045 2424 * * * * * * * 127 0 * * * * * * 2214 0 0 V 128 * 1402 * * * * * * * * * * * * 2045 * * 1399 * * 128 305 * 2394 * * * * 2214 0 0 Y 129 * * * * * * 2193 * 2225 * * * * * * * * * 1848 1788 129 0 * * * * * 0 2109 0 1000 H 130 * * * * * 1848 1788 * * * * * 1209 * * * * * * * 130 0 * * * * * 0 2109 0 1000 K 131 * * * * * * * * 1788 * * 1209 1848 * * * * * * * 131 0 * * * * 0 * 2109 0 1000 N 132 2045 * * * * * * * * 2379 * 2405 * * * 2394 2424 * * * 132 0 * * * * * * 2214 0 0 N 133 * * * * * 1202 * * 2394 * * 1415 * * * * * * * * 133 400 * 2045 * * * * 2214 0 0 K 134 * * * * * 2041 * * 1982 * * 1997 1981 * * * * * * * 134 0 * * * * 0 * 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