HHsearch 1.5 NAME c9c52A_ FAM FILE c9c52A_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9c52A_.a3m DATE Sat Mar 22 16:01:19 2025 LENG 1011 match states, 1011 columns in multiple alignment FILT 53 out of 55 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 3.8 EVD 0.3415 -7.3172 SEQ >ss_pred CCCCCCCCCCCHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH CCCCCCCCCCCCCCEECCCCCCCEECCCCCCCEEEEEEEEEEECCCCCEEEEEECCCCCCEECCHHHHCCCCHHHEECCCCCCCCEEEEECCCHHHHHHH HHHHCCCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHH HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC HHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCEEECCCHHHHHHCCCCHHHCCCCCCC CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC CCCCCCCEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHCCCHH HHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC CHHHCCHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCC CHHHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCHHHHHH HHHHHHHHHCC >ss_conf 9876655722321067578677387888877668999999999999997598887666689863228822489999999999999857999999999872 8899743624678534278887203568998778987567531489887999717886201035165269997781116888885599943503568888 8870666557000003356542116673015678864444433235533310355310011404110003788999827886440000122049999999 8799999863666899999999771667884888422898973186021228789999999999999999999999999999998642035552224810 2324677420002136840004679880267887327744345576411003667776104886127876898366424023101001201201355545 1112322334567704887117888888877735478998864384166316899999887530335677887740122337765544356766555544 4576621001300127870021013332212366433233045665317998279984331689999998421000223656533101201112188313 5566887424010315766420168668999999870889998999999999988487603578877776516603688888874210278865401763 0100042221357651133001222026899999999999986531887069999803168752453047899999999999999999872700155641 0120201111100136688889999897989871379999863188767876665676433752666720443012236799999999775257899999 99988775239 >Consensus xxexxRxNxvgiQxLsxxLhxqiFxxxxxxxxxxxxxxlxxxskxhLxxhxLxxkxtxxxxxixfxLPxLxGxnlxeHFxxigxxxxePyxxxxxxxxxx lpxxPxxWxxxxGWtrYxxxxxxexVxxPxexxlvFDVEvxxkxxxxpvlAxAxsxxAWYxWxSpxLxxxxxxxxLIPlxxxxxxklvVGHNVsyDRarv xEeYxlxxsxxxflDTMSLHvaxxGxxsxQrxxwxkxxKxxxxxxxxxxxxxxxxxxxxxxWxxxssxNSLxdVxklhcxxxlxKxxRdxFxxxxxxxIx xxfqxLmxYCAxDVxaTxxVxxklxPxFxxxxPHPVtfagmlxmxsxxLPvnxxxWxxYlxxaExxyxexxxxvxxxLxxlaxxaxxlxxxxexxxxDpW LxqldWtxqxxkxxkxxlpxkxqxxpGxPxWYxxLxxxxxxxxxxitxxxriaPxLlxLxWxgxPLxxxxxxGWxfxVpxxxxxxxxxkxxxxxxxxxxx xxxxxxxxxxxxxxxxffKLPHkxGxxxnvgxPlsKxflxxfexGxLxsxxxxAxxxLxxnxxxSyWxsxrdRIxxQxVVxxxxxxxxxxxxxxxtgxxx xxxxxxGxIlPqvixxGTvTRRAvExtWLTASNakxnRiGSELKAmVxAPpGYxlVGADVDSqELWIAsxxGDaxfxxhGxTaxgwMtLeGxKsxGTDlH SkTAxilGIsRdxAKVfNYgRIYGAGxkfAxxLLxqfnxxlsxxEAxxxaxxlyxxTKGkxxxxxxxxxxwxgGtESxlFnxLExiAxxxxPrTPvLgxx itxaLxxxxxxxxxflxSrINWvVQSsaVDyLHLlivsMxxlxxxyxixaRxxisiHDEiRylvxeedkyrxALALqisNlxtRaxfxxxlgixdlPqsv AFFSxVdiDxVLRKEvxxdCvTPSnpxxIpxGesldIxxxlxkxxgxlxxxxxxxxxxxxxxxxxxxxpvxxxxxxxxxxxxxxxxlxxqxxxxxxexxx xxxxxxxxxxx >c9c52A_ TAEAPRINPVGIQYLGESLQRQVFGSCGGKDEVEQSDKLMELSKKSLKDHGLWGKKTLITDPISFPLPPLQGRSLDEHFQKIGRFNSEPYKSFCEDKFTE MVARPAEWLRKPGWVKYVPGMAPVEVAYPDEELVVFDVETLYNVSDYPTLATALSSTAWYLWCSPFICGGDDPAALIPLNTLNKEQVVIGHNVAYDRARV LEEYNFRDSKAFFLDTQSLHIASFGLCSRQRPMFMKNNKKKEAEVESEVHPEISIEDYDDPWLNVSALNSLKDVAKFHCKIDLDKTDRDFFASTDKSTII ENFQKLVNYCATDVTATSQVFDKIFPVFLKKCPHPVSFAGLKSLSKCILPTKLNDWNDYLNSSESLYQQSKVQIESKIVQIIKDIALLKDKPDFYLKDPW LSQLDWTTKPLRLTKKGVPAKCQKLPGFPEWYRQLFPSKDTVEPKITIKSRIIPILFKLSWENSPVIWSKESGWCFNVPHEQVETYKAKNYVLADSVSQE EEEIRMNNLGLQCTGVLFKVPHPNGPTFNCTNLLTKSYNHFFEKGVLKSESELAHQALQINSSGSYWMSARERIQSQFVVPNCKFPNEFQSLSAKSSLNN EKTNDLAIIIPKIVPMGTITRRAVENTWLTASNAKANRIGSELKTQVKAPPGYCFVGADVDSEELWIASLVGDSIFNVHGGTAIGWMCLEGTKNEGTDLH TKTAQILGCSRNEAKIFNYGRIYGAGAKFASQLLKRFNPSLTDEETKKIANKLYENTKGKTKRSKLFKKFWYGGSESILFNKLESIAEQETPKTPVLGCG ITYSLMKKNLRANSFLPSRINWAIQSSGVDYLHLLCCSMEYIIKKYNLEARLCISIHDEIRFLVSEKDKYRAAMALQISNIWTRAMFCQQMGINELPQNC AFFSQVDIDSVIRKEVNMDCITPSNKTAIPHGEALDINQLLDKPNSKLGKPSLDIDSKVSQYAYNYREPVFEEYNKSYTPEFLKYFLAMQVQSDKRDVNR LEDEYLRECTS >UniRef50_UPI0001926FAB(47-543:543) PREDICTED: similar to DNA polymerase gamma, partial n=1 Tax=Hydra magnipapillata RepID=UPI0001926FAB E=1e-167 s/c=1.19 id=36% cov=45% --ESERINYANIQMLSPGLYKQLFK---YKQPSHVDSNICEKVKLHLEKHNLWGKTSTIAENIDFDLPQLQGENLDDHFNIVATEIVKEYKNLAEhmaNK LSTLPSMPEKWQMSEGWTKYNNSGTFEKVNAPDEDVLIFDVEVCMSIGDVPVLATAVSKSAWYCWVSDVLIQQKcsdpikklTPSLMIPLGTSNKKRLII GHNVCFDRSFVREQYSLEASNLRFLDTLSLHVCVSGITNEQR-NYMKSKSDAKVHF---------------DWMDVGAMNSLVKVYEFYCNKSIDKSSRD YFVTGSLQDIYENFQECVRYCAVDVQSTHAVFTSVWPMFCFHAPHPVTLLGMLEMGTSYLPID-ESWNHYLEQAEFIYNKMAKQMRHSLMAVADEALKMI ID-DKYKSDPWLWSMDWSIHKTAISKDNavlidkeddvhayiknrlnhlsEKRRNQlHLPGYPNWYRKLCMSPGeesyqSGPQSVSSQTRVTPLLLRMTW DGYPLHHEREYGWGFLVP---------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -------------------------------------------------- >UniRef50_C1EH81(251-938:972) Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1EH81_9CHLO E=6e-16 s/c=0.13 id=21% cov=59% ---------------------------------------------------------------------------------------------------- -------------------------------------------------------------WVDTMSLGDEGWKIFKPyFESPDVKK--VWHNYGFDR-H VIENHGVKLAG-FAADTM--HMA---------RLWNSNRKLEGGYSLEALSSDpkvMSDAGEMYSEAGEELIRSKRGMKKIFGKAKLKKdgTPGKTVILP PIDEIQTDPEQretWIEYSALDAQATWflreSLEAKLRGIDCEACP-------VLSKKPTFRRC-SNLWDfyvHYLREFGEVLTDMESNGmyvdKAHLAD AEKRALEDKKVAEDYFRAwatgkcPAAEHMNvgSGIQVRQLLFAGAPNKRRDKPGvektrefamvskeWTEWDEngregKAPKKAAKFELHGITKRNLQP ----------PVYTTTGLPAVSSVVLRALAGKPGAARELVDNWDALADDQKKDEALA----------------KKCGS----AFLA-FGGGFDGVEACAA IDALND-------VAAIDTLLSNFIIPlqsdnlrgfNGRVHAALN-INTETGRLSARRPSLQN-QPAL---------------------EKDRYGIR-KA F-SAEPGNILIVADYGQLELRL-------LAHMAGC-----VSMREAFEAGGDFHSRTAmgmykeireameqgkclleygdidddaggekpalvkDMFAS ERRKAKVLNFSIAYG---KTAHGLAKDF--GVSTREAEETVDLWYSDRPeVREWQAVQHKKAAEKGKVNTLLGRHRNLPE---------------ASSSD EMRRGHALRASINTPIQGGAADIAMLAMIQIHRCPRLRELGFKLLMQIHDEVILEGPEEHRDE-ALAL-------------------------------- ---------------------------------------------------------------------------------------------------- --- >UniRef50_Q9U208(15-1072:1072) Protein Y57A10A.15, partially confirmed by transcript evidence n=1 Tax=Caenorhabditis elegans RepID=Q9U208_CAEEL E=0 s/c=0.87 id=35% cov=83% ------------------------------------------------------------------LPPLVADNVVDHFGVLAEQQTRKYKELLEKAcef dletaknVLEHIDKTDGWHYKTGWTRYPFSTSepPETIDFPRDSILFFDIELVVRDGTLPTLAIALGRDAWYGWCSDRLIyESEIPEiptkaDLIPIGEI GMEKVIIGHNVGFDRARCREAYqSINGSKIRFMDTMSMSIPMYGMADHQQSLYEMY----------DVETNDSHSDWMNAWKGRVSKNSLVAVHdHLYPD KAINaegfskKTMRASFVKDPIEQIREDFQPLMSYCARDNILCAEIYFRLWPEFIKRFPHPATLSGMLNMGNVYLPINS-YWKMFYEKNVQTCEQKKTAA TRKIIESARLVAKRLDDEgeeiGPEKNDVWMWHHDWTF-------------NQKQSNF-EWFNKLFKARSFVNLsldevdshHIALKSHLIPAIFGFVFG PFPLFKTRSKGWGFLVPnwkpvekalqdpnfheidakidfkpdsavkkfplRSFYETVQNNVYMLGElPISPDRKGFELDEAGL---VRFYQLDHPSGEG -NVGDPLTKHFAKDLKELVLRPtrYEEYFDVVLDSIQTTQFWTSYSDRYCSEVAIW---------SPEATWRTAENLEMIDGAIAAAVVPAGTISRRSVH KLWVTLTNqSTGHVIGTGIKAMVQAPAGYRLVGADVDSQEQWLAALYGDASAekrlplekRVAGKTAFSNMMLAGSKSDNTDLHSVVASQLKISRNHAKV LNYARLYGSGETHAGKHLMRVG-GLKQSEAESTASQLFKLTKGDVAKYMKVdvrmncvvdkyieemvensdvckiltidgiyympaytsqfasetvrfed wllshyssllngssepdsliysiyenpdepRRLFVGGYESSTFNFLETSAAAHDLRTPILGCQIADSLGKlpegtpdSAYFDRKYKRSVMNWIVQSSAVD FLHLLLVSMQWLCDTYKIDARFVISIHDEVRYMCKEPDAPRLALALQLSNLLVRAYISQRVGICQLPNTVAFFSQVDCDTVLRKEVDTESINP-DGSKIA DGVAWTVDDLLKLTGGKLD-------------------------------------------------------------- >UniRef50_B7WQQ7(465-733:766) DNA-directed DNA polymerase n=1 Tax=Comamonas testosteroni KF-1 RepID=B7WQQ7_COMTE E=1e-42 s/c=0.66 id=25% cov=20% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------------------------------LRSAVTAPEGSVIISADYSQIELRIAACFAE---KMRAGTGLPGM-LATAFRTGVDPH LTTAlqsvrqrgdidftgnaaayiaglcdeercelkSRLFVERDTAKAQNFGLLYGmKDSSFWEYGRLAYGLTWTFEEAQAARDAWFKMYPEIALLHDSY QSTFSAAAKETLFLKAHDGVFQTTTSRVVSGATLS---GRKVTATSPFL--LLSYACQGTGADIIISAIASMDHGTRRHLVNV-----VHDEL------- ---------------------------------------------------------------------------------------------------- -------------------------------------------- >UniRef50_A7XX31(49-698:728) DNA polymerase I n=2 Tax=unclassified Siphoviridae RepID=A7XX31_9CAUD E=3e-86 s/c=0.50 id=26% cov=55% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------VVYHNAAYDRRVL AVTLDIPLDQTYGDDTMvALH-----LVDENHPLGLK-EWAKTLLGLEEVNADIEPPELtDEDQVEAVSKNGRRYKKKVHkLKPDWLQRLKDAFLAvhng gvsyGALYKLLNRaFQQLKN---RGVVS----YTGSFPNDFRLFP--VDIAAIYALDDAM--NTLALWEHvevFFElhpKLHALYREIELPVND-VMTRA THRGVLVDKEE-------LRRIKETIQ------ARIEEKAQEA---QELLKALIGSKASEFTNpLNSPQQLATILYDLL--GYPVVETTPNG-------- ---APSTSKTAIAKLLTLSPKDKRKA-------------------------PLAKAFL----------EAKQAHEGLK--KLLS---TYTDSILEE-VDP QGRLHTNFNTVGTVSGRMSSSNPNLQN-LPRLLP-----EEVAEKPYLQGIDIR--------KAFV-ADPGYIFVSADYASMELVVcAAVSGDP------ -------TMRDLLNQGRDLHAYTARyafKVGLDlddkafkeqykdyRQKAKVVNFALIYG-GTEF--TLIKNF--GFSEEEAKQLIQGYFEAYPvVKTWM EEVYRELEEKGfVEYPIYGYIKRMdlpqALRKLPkdKWPlVLN-------NDPDARKQYYasLRSCQNALIQGFSAFVVKDAIVQMQRAFEAEGLDAQVI IQVHDEIVVLAKEEHAERVA-------------------------------------------------------------------------------- ---------------------------------------------------------- >UniRef50_UPI000187E65C(16-542:565) hypothetical protein MPER_07935 n=1 Tax=Moniliophthora perniciosa FA553 RepID=UPI000187E65C E=7e-80 s/c=0.57 id=35% cov=32% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------------------------------------------------RWEDLTSANSLVDVAKLHCNIDISKEIRGDFMTATPEEIR TDITDYLAYCAGDVDVTHNVYRKVLPGFLNACPHPVSFAGVLTMGSGFLPVNEQ-WEAYLERAEGVWQALEKKVRDGLEKLARSAMEAYPVavpgednia NEGWRNDVWLSQLDWTPKIagktrgvlpltipepqfdtvpsppkalpawyamvqseplgkksmerifpllLRLAFDGVPmsftpsekwfynrdgdisrlp taingkktisilyrqhalplledtsmtscdvelakNITQGETGedivkavlelarvayetpasereqdpwlrqldwkeyevnsagevkprskkaakppkp ppvyWPKWFWDLTKPKKDMPPGsldITIRNRYAPLLLKMSWHGYPLFFSREHGWTFRVPTRPTEDFdpavvasaQEKFQRLTALSFYEPEDDKLAEASLR DGYVFYKLPHKDGDKANVGSPLTKGFLRFAMDGVMTSHAgDELKELVDIGVKSSYWISARDRIMNQRVEW------------------------------ ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- >UniRef50_B5YDJ0(464-820:856) DNA polymerase I n=3 Tax=Dictyoglomus RepID=B5YDJ0_DICT6 E=3e-65 s/c=0.71 id=23% cov=34% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ----------------------------------------------------------------PVLYSMEK-WGIKVDKEYLKQLSDEFCERIKKLEEE IYElagtrFNLNSPKQLSEVLFERLKLPSGKKGKTGYSTSSSVLQN-----LINAHPIVRKILQYRELYKLKSTYVDAIPNLVNPQTGRVHTKFNPTGTA TGRISSSEPNLQNI-PIKSEEGRKIRRAFV-----------------------SEDGYFLVSLDYSQIELRIMAHLSQEP------------KLISAFQK GEDIHRRTASeIFGVPeeevddllRSRAKAVNFGIIYG-----ISSFGLSETVSITPEEAEKFIDSYFKHYPrVKLFIDKTIHEAREKLYVKTLFGRKRY IPEIK-------------SINKQV--RNAYERIAINAPIQGTAADIIKLAMIEIYKEIENKNLKSRILLQIHDELILEVPEEE----------------- ---------------------------------------------------------------------------------------------------- -------------------------- >UniRef50_A8IFA9(149-569:609) DNA polymerase I n=2 Tax=root RepID=A8IFA9_AZOC5 E=9e-26 s/c=0.29 id=24% cov=30% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---QEMQDYCEQDVEVTFRLYQKIkekgWKEESIELEHRVQWIIHRQEQYGFLFDQAKAASLYADLVQRK-TELEAELQSAFPPWEVESVFVPKVNNRV- ---------------RGYVKGVP----------------FTKRRTIHFKPSSRDHIAGRL------------KAKYGW---------------------- ---EPSEFTDEGKPKVDEDVLSHLP----------YPEAK---------LLSEYLMVEKRLGQIATGKEAWL--------KHVKADGRIHGDVTTNGAVT GRMTHSKPN----IAQVPGNGSP-------------------YGHRCRELFVAAKRKLLVGCDADALELRCLA----GYMARYDGGAYVRTVLEGKKELG TDMHTLNAKALGCSRDVAKVWFYAFIYGAG---------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- --------------- >UniRef50_D0Q1A1(153-647:678) DNA polymerase n=2 Tax=T7-like viruses RepID=D0Q1A1_9CAUD E=2e-12 s/c=0.16 id=19% cov=33% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -----MMDYCKQDVQVTLKLFEKFmsdtwyFPNGADglsesvLLEHEAAWLLAKQERNGYAFDT--------QGAERLYAEVAGRRAEILMELTRTFGSW YEPKG-------------GTQPFLHPKSGKPLHKYPRVKYPK-AGSIWTSAKKPTLAKTLYLKDAPF--------TPIQHVT-----FNPSSRAHIIKVL KDCGWVPTDFTE-----AGNPIVDDDTLSLVIEHKLVPE---------EFLPKVE---LIKEYLVIQKLIgQLAEGDNAWL---------RMDKGGYIHG QVNPNGAVTGRATHSYPNL-AQVPSIRKYKGVECRSL--------------FGAEHHRDYHTGKPWIQVGVDASGLELRCLGHFMAKFDDGEYINTI--- -------LNGDIHTQNQIAAGLpTRDNAKTFIYGFLYGAG------------------------------------------------------------ ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------------- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * T 1 * * * * * * * * * * * * * * * * 0 * * * 1 0 * * * * * * 1573 0 0 A 2 1566 * * * * * * * * 3192 * * * * * 1195 3110 * * * 2 0 * * * * * * 2371 0 0 E 3 * * * 328 * * * * * * * * * * * 4035 2811 * * * 3 0 * * * * * * 2573 0 0 A 4 2024 * * 4197 * 4060 * 3929 3346 * * * * 3445 * 1381 * * * * 4 0 * * * * * * 2797 0 0 P 5 3409 * * 4794 * * * * * * * * 709 * 3077 2842 * * * * 5 0 * * * * * * 2797 0 0 R 6 * * * * * * * * 4918 * * * * * 49 * * * * * 6 61 * 4592 * * * * 3149 0 0 I 7 * * * * 5070 * 2936 1379 4324 3937 4414 * * * 3287 * * 3183 * 3637 7 0 * * * * 0 * 3115 0 1000 N 8 * * * * * * * * * * * 45 * * * 5030 * * * * 8 0 * * * * * * 3231 0 0 P 9 3312 * 5276 2340 * * * * 4357 3905 * * 1141 4160 * 4938 * * * 5755 9 0 * * * * * * 3231 0 0 V 10 4348 * * * 4357 * * 2323 * 2303 4823 * * * * * * 1107 * * 10 45 5030 * 1585 585 * * 3231 1000 0 G 11 * * 3736 * * 480 * * 3905 * * 2824 * * * * * * * * 11 0 * * * * * * 3231 0 0 I 12 * * * * * * * 763 * * * * * * * * * 1283 * * 12 0 * * * * * * 3320 0 0 Q 13 * * 4194 * * * * * * * * * * 81 * * * * * * 13 0 * * * * * * 3320 0 0 Y 14 * * * * * * 4219 * * 2802 1221 * * 3223 * * 5175 * * 2064 14 0 * * * * * * 3354 0 0 L 15 * * * * * * * 3671 * 252 5107 * * * * * * 4245 * * 15 0 * * * * * * 3354 0 0 G 16 5189 * * 4907 * 5319 * * * * * * 2987 * 5175 463 * * * 4836 16 0 * * * * * * 3354 0 0 E 17 4893 * 3388 2073 * 4289 5107 * 4028 * * 4245 2241 5131 2758 4293 * * * * 17 0 * * * * * * 3354 0 0 S 18 4116 * 4183 5335 * 3298 2812 * 3306 * * 2978 4836 4907 4245 2430 4014 * * 5512 18 0 * * * * * * 3354 0 0 L 19 * * * * * * * 5709 * 193 * * 5175 * * * * 3671 * * 19 0 * * * * * * 3354 0 0 Q 20 * * * * 5017 * 587 * * * * 5175 * 3183 * * * * * 2595 20 0 * * * * * * 3354 0 0 R 21 4284 * 4836 2491 * 4769 5175 * 2115 * * 3513 * * 2290 3069 5087 * * * 21 0 * * * * * * 3354 0 0 Q 22 * * * * * * 4245 * 3743 * * * 5175 288 5275 * * * * * 22 0 * * * * * * 3354 0 0 V 23 * * * * * * * 1386 * 1312 * * * * * * * 2220 * * 23 0 * * * * * * 3354 0 0 F 24 * * * * 41 * * * * * * * * * * * * 5175 * * 24 127 * 3573 * * * * 3354 0 0 G 25 * * * * * 1878 * * 2883 * * 4803 1122 * 3900 * 5058 * * * 25 76 * 4289 * * * 0 3325 0 1766 S 26 4944 * 2895 3550 * 3863 5155 * 3505 * * 3485 3240 2936 3463 3099 5073 * * * 26 49 * 4893 * * * 0 3302 0 2145 C 27 3875 5073 * 5108 * 2355 * 5007 4046 4786 * * * 4825 * 2862 2013 4987 * 3356 27 109 * 3777 * * 2747 233 3284 0 2350 G 28 4887 * 4960 4870 * 3343 4633 * 5058 * * 1881 2601 * 4285 2039 * * * * 28 198 * 2965 * * 814 1213 3267 0 2623 G 29 4075 * 4492 4656 4973 3406 * 4224 3915 4442 3679 * * 4677 3771 3928 2418 3314 * 5594 29 154 * 3304 * * 1606 574 3185 0 2372 K 30 * * 3535 * * * 4787 4998 2729 * 3761 3250 4669 2150 4795 * 2794 4720 * 4889 30 352 * 2209 * * 2843 216 3173 0 2494 D 31 4751 * 1666 3553 * * * * * * * 2815 2661 3644 4543 3399 4487 * * * 31 60 * 4608 * * 1908 447 3087 0 2817 E 32 4385 * * 2427 * * * 2984 3643 3822 * * 5512 3771 4660 2911 * 3597 * 2849 32 199 3779 4157 2000 415 2216 350 3183 1266 2555 V 33 * * * 3737 * * * * 4865 2793 * 4403 1858 * 4698 2366 4578 3139 * 4820 33 0 * * * * 1776 498 3147 0 2520 E 34 * * * 2299 * * 5658 * 2372 * * 3658 3024 * 3883 3695 3110 3050 * * 34 0 * * * * 647 1469 3184 0 2350 Q 35 4669 4873 3817 4101 * * * 3927 3995 3317 * * 1513 3459 * * * 3516 * 4648 35 169 3178 * 0 * 833 1190 3217 1507 1449 S 36 3758 * 2146 4097 * 5023 4732 * 3448 * * 3175 2526 5065 5052 2863 * * * * 36 0 * * * * * 0 3268 0 1000 D 37 5052 * 3967 2190 * * * * 3222 * 4801 4686 1962 2879 * 4489 4728 5065 * * 37 155 3295 * 1868 462 * 0 3268 1752 1000 K 38 1907 * 5112 2007 * * 5648 4686 2335 3940 5184 5881 * 5030 * 5180 * 5017 * * 38 0 * * * * * 0 3268 0 1000 L 39 2650 * 4728 * * * 5060 3668 * 825 * * * 4449 5232 5065 * * * 5180 39 0 * * * * * 0 3268 0 1000 M 40 5065 5881 * 3417 * * * 2123 * 1757 5248 4801 * * 5052 * 5184 2223 * * 40 43 5102 * 3700 115 * 0 3268 1000 1000 E 41 4107 * 3214 1590 * * * * 2665 5232 * 3437 * 2896 4101 4936 * * * * 41 44 * 5052 * * * 0 3268 0 1000 L 42 * * * 4864 * * * 2317 4162 1596 3571 4639 * 4415 3294 * * 3758 5003 * 42 0 * * * * 850 1167 3259 0 1430 S 43 2030 3316 * * * 5030 * 4732 * * * * * * * 973 * 5881 * 4058 43 0 * * * * * 0 3268 0 1000 K 44 * * * * * * * 4449 692 4941 5441 * * 3431 3510 * * 3335 * * 44 0 * * * * * 0 3268 0 1000 K 45 * * 2074 2924 5060 * 3809 * 2457 3672 * 4732 * * 5112 3634 4165 5052 * 4801 45 0 * * * * * 0 3268 0 1000 S 46 * * 4801 4058 4165 * 474 * * 4686 * * * * * 5248 4941 * * 5030 46 0 * * * * * 0 3268 0 1000 L 47 * * * * * * * * * 0 * * * * * * * * * * 47 53 * 4801 * * * 0 3268 0 1000 K 48 2637 * 3721 5813 * * 4966 * 1558 * 4858 * * 3235 2574 4894 4975 * * * 48 0 * * * * * 0 3241 0 1443 D 49 4967 * 3579 4831 * * 4218 * 2613 4982 5142 4126 * 2507 2216 5069 3902 * * 5215 49 0 * * * * * 0 3241 0 1443 H 50 * * * * 4385 * 463 * * * * 2360 * 4967 * * * * * * 50 0 * * * * * 0 3241 0 1443 G 51 * * 1878 2638 * 1467 4975 * * * * 3596 * 3456 * * * * * * 51 0 * * * * * 0 3241 0 1443 L 52 * * * * * * * * * 150 4831 * * * * * * 3972 * * 52 0 * * * * 1131 880 3241 0 1443 W 53 4767 * 3115 * 3722 * 4871 3599 4971 1445 * * * * * * * 4914 2166 * 53 0 * * * * 0 * 3330 0 1000 G 54 3958 * 3548 * * 984 * 4143 * * * 5145 2379 5017 * * 4769 * * * 54 0 * * * * * * 3354 0 0 K 55 5249 * * 2633 * * 5096 * 896 * * 4769 * 5102 5301 3381 5012 5175 * * 55 0 * * * * * * 3354 0 0 K 56 * * 3885 2890 * 4270 * * 1723 * * 3415 3524 3481 * 3646 3433 * * * 56 0 * * * * * * 3354 0 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