HHsearch 1.5 NAME c9baoB_ FAM FILE c9baoB_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9baoB_.a3m DATE Sat Feb 1 08:50:04 2025 LENG 102 match states, 102 columns in multiple alignment FILT 103 out of 365 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 6.8 EVD 0.4011 -2.0430 SEQ >ss_pred CCCCEEEEEEEEECCCCEEECCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEEEEECCCEEEEEECCCEEEEEE CC >ss_conf 9872468889984237839647854667654005875566676711578999998512877778886033204761589983893899994691795432 29 >Consensus dxxCxrxxxxVdFxxxxWIixPxxxxaxyCxGxCxxpxxxxxxxxxxhaxxxxxxxxxxxxxxxxpCCxPxxxxxlxilyxxxxxxxxxxxxxmvvxxCg Cr >c9baoB_ DGPCALRELSVDLRAERSVLIPETYQANNCQGVCGWPQSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAGKLLISLSEERISAHHVPNMVATECG CR >UniRef50_Q9Z0J7(217-302:303) Growth/differentiation factor 15 n=6 Tax=Murinae RepID=GDF15_MOUSE E=2e-15 s/c=0.97 id=25% cov=85% -----------DLGWSDWVLSPRQLQLSMCVGECP----HLYRSANTHAQIKARLHGLQPDKVPAPCCVPSSYTPVVLMHRTDSGVSLQTYDDLVARGCH C- >UniRef50_O00292(263-353:366) Left-right determination factor 2 n=8 Tax=Theria RepID=LFTY2_HUMAN E=1e-07 s/c=0.63 id=26% cov=83% ---CCRQEMYIDLQgmkwAKNWVLEPPGFLAYECVGTCQQPPEALAFNW--------------PFLGPRQCIASETASLPMIVSIKEGGrtrPQVVSLPN MRVQKCSC- >UniRef50_O61643(842-945:946) Inhibin beta chain n=11 Tax=Endopterygota RepID=INHB_DROME E=9e-29 s/c=1.22 id=25% cov=100% NGQCCKESFYVSFKalgWDDWIIAPRGYFANYCRGDCTGSFRTPDTFQTFHAHFIEEYRKMGLMNGMRPCCAPIKFSSMSLIYYGDDGIIKRDLPKMVVD ECGC- >UniRef50_P05111(262-365:366) Inhibin alpha chain n=26 Tax=Theria RepID=INHA_HUMAN E=3e-11 s/c=0.67 id=21% cov=96% ---CHRVALNISFqelGWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVPGA-PPTPAQPYSLLPGAQPCCAalPGTMRPLHVRTTSDGGYSFKyeTVPN LLTQHCAC- >UniRef50_UPI00017B2208(65-164:166) UPI00017B2208 related cluster n=2 Tax=Tetraodontidae RepID=UPI00017B2208 E=6e-11 s/c=0.69 id=22% cov=96% DSSCGLRSILLQVRDLGLGYDSDEAVLFkYCGGACPRITSNHDLTLANllHSGVLPQLAPGEPW-HHTPCCRPTHHEDMAFL---DNSHRWHKVEKLSAA GCTC- >UniRef50_Q6VZT3(178-282:282) CNPV064 TGF-beta-like protein n=1 Tax=Canarypox virus RepID=Q6VZT3_CNPV E=8e-08 s/c=0.56 id=15% cov=99% --TCTTKQKYLDLKYLDMddtIIAPRGITFKYCSGYCDINSMKNFYSNSLYGILaMKFISLKAINSNFKRCCYPESMENISILYIDpNGNIKKGELVNST ISKCVCK >UniRef50_A9YRX4(262-366:372) Tgf-beta n=1 Tax=Amphimedon queenslandica RepID=A9YRX4_9METZ E=2e-12 s/c=0.70 id=21% cov=97% ---CSKSSLSIDKGQLAQILDieidfPETFDLNVCGGHCPGSkyINQFHSKITYLLLATSEVEHLANKHHYSKTCVPTKYHSLNYIKFDQNGSVIKTLDQ FSVAECSC- >UniRef50_Q9J5D1(269-362:363) ORF FPV080 Transforming growth factor-beta n=2 Tax=Fowlpox virus RepID=Q9J5D1_FOWPV E=7e-09 s/c=0.65 id=14% cov=91% ---CKVYRKYINFRSigLKWILHPPGIDYGYCMGECQSFVYTDSFLYS------LLAFHYIDGIELKQCCSIQSMDDLVVHYRLGRTPKTAILRKVSVKS CKC- >UniRef50_B0YLF5(195-305:307) Gonadal transforming growth factor beta-like protein n=1 Tax=Crassostrea gigas RepID=B0YLF5_CRAGI E=2e-08 s/c=0.54 id=22% cov=96% --TCNVVPWTVDFAELGWdkfISFPLTYNANACEGKCAqsrncvSAMNKPINMLKNYEILRRLYaYCPDVSLLDHSCCRPSKYGSQGIVFRGaSGSLFFI VVSQMRVLEC--- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * D 1 * * 730 2054 * * * * * * * 2678 * * * * * * * * 1 0 * * * * * * 4712 0 0 G 2 3778 * 5405 * * 1212 * * * * 5292 5231 2579 4743 * 3272 3164 * * * 2 0 * * * * * * 5505 0 0 P 3 4641 * * 5037 * 3633 * 4289 4208 4065 * * 1680 4653 3643 3777 2481 * * * 3 35 5383 * 2322 322 * * 6047 1000 0 C 4 * 0 * * * * * * * * * * * * * * * * * * 4 0 * * * * * * 6713 0 0 A 5 4633 1259 5903 5292 * 4799 3895 * 5013 6163 * 5150 * 4112 3043 3323 5058 6136 * * 5 0 * * * * * * 6713 0 0 L 6 6934 * * * * * * 4889 3119 1833 6930 * * * 1180 6582 5037 3799 * * 6 15 6562 * 2000 415 * * 6713 1000 0 R 7 5650 * * 3834 4786 4939 3320 5458 3696 6805 * 6451 * 3459 1813 5024 5913 4046 5308 3156 7 0 * * * * * * 6713 0 0 E 8 4239 * 2981 3121 * 6447 5408 * 5103 5587 * 4069 2890 4779 4119 1877 4717 * * 5520 8 0 * * * * * * 6713 0 0 L 9 * * * * 2068 * * 5094 3824 1372 3144 6324 * 6165 6583 5475 6595 4522 5098 5654 9 0 * * * * * * 6713 0 0 S 10 * * 4844 3712 4268 * 5401 6318 4858 4717 * 4204 5296 * 3777 3893 3015 3976 6890 1678 10 0 * * * * * * 6708 0 0 V 11 6507 * * 6572 6600 * * 1958 * 3161 5368 * * * * * * 799 * * 11 31 5552 * 1585 585 * * 6708 1485 0 D 12 6942 * 1233 6318 * * 6388 * 4212 * * 2680 6256 5283 * 2070 4470 6677 * * 12 17 6450 * 1585 585 * * 6708 1000 0 L 13 * * * * 421 * * * 5782 2520 * * * * * * * 4040 * * 13 295 2618 5514 1585 585 * * 6707 4063 0 R 14 3448 * 4884 3900 * 2140 * * 2703 6372 * 4868 * 3115 2698 3607 6963 5569 * * 14 357 2290 6104 1627 564 * 0 6700 4500 1353 A 15 3347 * 2537 2743 * 6429 * * 4459 * 6695 * * 4037 6542 5034 6568 * 1387 5767 15 382 2104 * 1270 773 621 1515 6678 4817 1618 E 16 5067 * 2461 3742 6983 3702 5850 5506 6235 1979 5003 4238 * 5884 * 4005 6717 * 2871 6256 16 179 3096 * 1621 567 0 * 6690 3712 1000 R 17 5134 * 1841 3950 * 2515 3989 * 3395 * * 3094 * 5492 3859 3896 5708 * * * 17 55 4745 * 1394 691 * * 6707 2162 0 S 18 * * * * 3956 * 5241 * * 3793 5788 * * 5785 * 4207 * * 485 4963 18 120 3645 * 1257 782 * * 6708 3429 0 V 19 * * * * 6305 4058 * 636 * 6453 5964 * * * * * * 1964 * * 19 0 * * * * * * 6701 0 0 L 20 6944 * * * 6898 * 5055 1471 * 1589 5264 * * * * 6121 * 2646 * 4058 20 28 5683 * 0 * * * 6701 1000 0 I 21 1500 * 4888 2684 4689 6631 4172 6469 * 5623 7032 * * 4645 6192 2472 6279 * * 3903 21 26 5800 * 2322 322 * * 6701 1000 0 P 22 * * 5683 * * * * * * * * * 89 * * 4624 * * * * 22 10 7116 * 0 * * * 6701 1000 0 E 23 4128 * 5983 3075 * * 5740 * 1743 4505 * 6453 2739 5749 2650 3471 5836 * * * 23 0 * * * * * * 6701 0 0 T 24 5579 * 6631 3516 * 1557 6650 5532 3920 5170 * 6862 * 6362 3552 2981 2663 5283 * * 24 23 5977 * 0 * * * 6701 1000 0 Y 25 4323 * * * 1398 * * 3890 6397 4732 * * * * * * 5278 4624 * 1368 25 0 * * * * * * 6701 0 0 Q 26 5561 * 2319 3067 6833 * 4497 4823 5794 4285 5572 2387 * 3527 5789 5971 3755 4233 6648 5000 26 0 * * * * * * 6707 0 0 A 27 883 * * * 3684 * * 3618 * 3396 5335 * 4401 * * 5611 4145 5576 * 4902 27 0 * * * * * * 6707 0 0 N 28 7021 * * * 3357 4329 4473 * 5820 6504 * 1828 * 6499 3563 4181 4125 * * 1828 28 57 4689 * 0 * * * 6742 1465 0 N 29 6252 * 5495 4180 3026 * 5669 * 6787 5515 4212 4472 * 4161 4168 * 7054 4197 * 1109 29 0 * * * * * * 6935 0 0 C 30 * 0 * * * * * * * * * * * * * * * * * * 30 0 * * * * * * 6935 0 0 Q 31 3258 * 5801 4214 * 3788 4388 4468 3264 5909 5055 5286 * 4360 3422 2414 5211 3483 * 4803 31 0 * * * * * * 6935 0 0 G 32 * * 5491 * * 53 * * * * * * * * * 6191 * * * * 32 0 * * * * * * 6935 0 0 V 33 3339 * 4501 3716 * 3585 4578 5083 3280 5336 * 6554 5081 4908 4516 2496 3003 4288 6517 5861 33 0 * * * * * * 6935 0 0 C 34 * 32 * * * * * * * * * * * * * * * 5491 * * 34 135 6345 3704 2322 322 * * 6935 1000 0 G 35 3519 5392 4479 4806 5871 3943 5405 6487 3933 4757 * 5886 1849 3815 4192 3723 4147 5261 * 6554 35 112 6021 4070 2585 263 * 0 6915 1000 3327 W 36 4354 * * 5103 2330 3908 4363 4971 4418 4167 * 4749 * 4347 3106 3227 4891 4327 6385 3860 36 147 * 3364 * * 3727 113 6936 0 4139 P 37 3906 * * 6423 5822 4941 3905 4738 * 4168 5483 4446 1097 6033 6913 3591 4330 5684 * * 37 106 5326 4452 772 1271 1655 551 6889 1568 4930 Q 38 4998 * 6405 4740 4854 6256 5189 3950 6458 2086 3888 5613 4170 4066 3642 3488 4151 3984 5509 5728 38 75 * 4310 * * 2103 382 6835 0 4822 S 39 3553 * 5374 5618 5955 3462 6548 6979 5824 3636 5762 3539 3779 4040 3634 2355 3854 6499 * 4253 39 248 5152 2946 1535 611 1278 767 6932 1557 4771 D 40 4120 * 2437 4289 5469 4016 3180 6377 4037 4989 5563 3444 3964 3614 * 4990 3093 * * * 40 59 5732 5571 1750 509 1080 924 6638 1715 5063 R 41 4652 * 4363 4255 4738 4499 3997 4886 3208 4764 6786 3768 3426 3438 3673 3957 4779 5825 * 3806 41 106 5692 4286 0 * 1650 554 6833 1572 4338 N 42 4849 * 3146 * 4152 4348 2682 5156 * 3795 5526 2747 6693 6355 * 3751 4031 4898 5987 3135 42 153 * 3317 * * 1233 799 6859 0 4265 P 43 4564 * 6118 * 3402 4882 * 4299 4259 3168 3662 4595 3857 5364 4093 3085 4599 3628 * 3502 43 73 * 4350 * * 777 1264 6871 0 4766 R 44 4241 * 4440 5696 5718 5430 3830 5610 4139 2711 5330 1941 5064 4486 5114 3945 4031 6086 * 6665 44 25 * 5877 * * * 0 6918 0 4128 Y 45 2030 * 6273 6622 3769 5611 * 4733 5541 3284 4254 5185 2864 5662 5516 3773 3830 6434 5573 4586 45 134 * 3494 * * 2315 324 6979 0 4328 G 46 3873 * * 5593 4588 6187 * 6462 4643 5248 4735 4102 4995 6168 * 2052 1771 4734 * 3937 46 81 * 4201 * * 3958 96 6896 0 4736 N 47 * * 6268 * 3377 3780 3765 * 4845 4670 4389 1243 4277 5238 5242 6400 4926 6265 6515 5222 47 161 5563 3567 1000 1000 1709 527 6840 1000 5041 H 48 5338 * * 5629 6554 4357 714 6193 * 3595 4862 6108 * * * 5336 * * * 3110 48 16 * 6502 * * 2108 381 6627 0 5278 V 49 966 * * 6000 6449 4836 * * 5933 3968 6221 6266 * 6471 * 2960 2829 4694 * * 49 19 * 6241 * * 4003 93 6696 0 4688 V 50 4518 * * 6130 5658 4307 5650 1909 4188 3534 3792 5222 * 4534 4283 3946 3802 3336 * 6029 50 54 6333 5355 1585 585 2056 397 6687 1000 4830 L 51 4169 6187 6458 6659 6684 6835 * 2227 * 1816 4483 6462 5340 5523 6304 5860 5594 2134 * 6328 51 48 4947 * 444 1916 1856 466 6741 1685 4573 L 52 * * * * 5607 4324 * 4388 3210 2477 3386 * 4536 1668 4395 5172 4880 5768 * 6259 52 0 * * * * 1184 837 6831 0 3984 L 53 3479 * 5329 5267 5699 3789 4653 * 4038 4275 * 2724 5281 5224 4785 2096 2964 * * 6208 53 0 * * * * * 0 6878 0 2960 K 54 6444 * 6386 4656 5780 * 6352 3063 3685 1695 6695 5656 4589 3724 3874 2874 6597 4692 * * 54 36 * 5355 * * * 0 6878 0 2960 M 55 3855 * * 5942 5415 5456 5501 3287 5207 2568 2688 6535 5674 * 5233 3945 5849 3061 6396 3035 55 50 5345 6718 910 1096 1509 624 6846 1705 3417 Q 56 5306 * 6702 5310 3832 * 2635 4372 4108 5267 * 3160 4171 3565 2812 4409 3887 6528 * 4141 56 0 * * * * 2976 196 6859 0 3004 A 57 3366 5339 6624 3410 4921 3712 4421 6360 3802 3619 4517 5108 4069 4145 3703 3020 4861 5643 * 6708 57 30 5604 * 1242 793 2246 342 6871 1525 2883 R 58 4473 * 5217 6987 4566 4143 3486 5109 3229 2771 4071 4866 4588 5497 3414 3563 4681 4699 * 4774 58 14 * 6733 * * * 0 6876 0 2632 G 59 3693 * 4259 4653 * 2287 6755 5153 3380 4112 6362 2738 5770 4755 6533 3866 4592 5077 5217 4648 59 125 4929 4312 0 * 2633 254 6877 1985 2811 A 60 3986 * 3319 5754 * 6162 * 4644 3315 3657 * 4244 1903 4847 4766 3527 5104 3697 * * 60 56 5251 6370 1159 856 1484 638 6830 1576 3741 A 61 4651 * 3582 5063 4747 3912 4164 * 3213 5060 6720 3226 4013 3572 5285 2843 4806 4267 5190 7159 61 71 6468 4756 0 * 1832 476 6889 1000 3273 L 62 3301 * 3716 4859 * 3840 5152 4503 3664 3495 * 3632 4634 6577 3795 3372 3879 3631 * 5076 62 80 6547 4521 0 * 1911 446 6767 1000 3650 A 63 3741 * * 3905 6690 2862 4678 4236 * 4235 * 3329 4741 4762 3874 3666 4670 2280 * * 63 72 5126 5643 1649 554 1688 536 6788 2127 4124 R 64 3629 * 4652 5322 5742 4863 4458 3685 4668 4800 4475 4945 1577 6535 3936 4536 * 4535 * 5162 64 65 4861 6663 1932 438 1930 439 6793 2036 4050 P 65 3488 6151 6956 4044 * 3289 4771 * 3168 * 5093 6746 3256 3093 2868 3306 3656 * * * 65 78 4536 6674 934 1070 912 1094 6824 2711 3611 P 66 3825 7079 * * * 6971 * 5147 6139 3751 6592 * 832 3953 4826 3433 5494 6535 * * 66 23 5982 * 2322 322 1325 735 6926 1064 2629 C 67 * 244 * * * * * * 5463 * * * * 6821 5935 3828 4736 * * * 67 27 6491 7059 2585 263 0 * 6915 1000 1822 C 68 * 67 * * * 6260 * 6210 * * * * * * * * 7147 6370 * * 68 0 * * * * 0 * 6949 0 1000 V 69 2549 * * * * 5651 4702 4572 5424 * * * * * 2907 3640 4295 1340 * 4440 69 60 5580 5649 1000 1000 * * 6935 1128 0 P 70 4700 * * * * * * 6237 * * * * 157 * * 4648 * 6458 * * 70 0 * * * * 0 * 6924 0 1335 T 71 4208 * 5007 4147 * 5026 * 3246 4067 6999 * 4943 * 4962 6820 2870 1662 3166 * 5855 71 12 6898 * 1000 1000 * * 6935 1000 0 A 72 3447 * 4860 3088 * * 5455 * 2320 5684 6382 5084 * 3690 2552 3579 3396 5422 * 5491 72 29 6604 6729 0 * * * 6935 1000 0 Y 73 6244 * * * 3376 * 6071 * * 2160 2269 * * * 4010 5022 3993 * * 1792 73 0 * * * * * 0 6867 0 1000 A 74 3847 * 3421 2671 * 3825 5436 5313 4246 6762 * 4815 * 5446 3283 1951 3949 * * 6076 74 40 * 5203 * * 0 * 6867 0 1000 G 75 3832 * 3001 * 6675 4497 5418 6557 6856 5304 6479 4592 1677 * * 1760 6696 * * 6326 75 14 6719 * 0 * * 0 6807 1000 1387 K 76 * * 5752 * 4660 * 6793 2396 6480 1340 2775 6557 5304 4512 * * 6719 3303 * * 76 0 * * * * 0 * 6807 0 1387 L 77 4140 6336 3941 5372 * 6252 6566 6685 3931 4479 5296 3868 4146 6544 5102 1746 2744 4456 * 6100 77 12 * 6908 * * * * 6935 0 0 L 78 5050 * 6531 5767 3497 * * 2081 6829 2293 2478 * * * * * * 2324 * 5396 78 33 5484 * 0 * * 0 6868 1595 1000 I 79 * * * * 5197 * 6265 2150 * 1325 3105 * * * 4304 * 4377 3317 6638 6634 79 77 7347 4438 0 * 0 * 6868 1000 1000 S 80 * * 5884 5585 3295 * 4526 5717 5042 4842 6882 * * 5803 * 3329 5038 3639 6289 1049 80 33 5471 * 0 * * 0 6857 1000 1837 L 81 6723 * 6577 7015 2437 * 6768 3087 4284 2347 4046 6546 6266 4437 4435 5405 4903 4167 * 3017 81 40 5196 * 2209 352 * 0 6857 1625 1837 S 82 * * 1593 3040 6842 4534 5600 6478 5277 3353 * 2634 * 6882 6974 3258 4824 5496 * * 82 241 2701 * 89 4060 0 * 6857 4521 1837 E 83 6667 * 2106 2068 * 2685 5312 * 5212 * * 3051 4856 4035 * 3532 6780 * * * 83 37 5319 * 0 * * * 6935 1977 0 E 84 * * 2044 3706 6100 3118 5099 * 4630 6612 * 2057 6957 5220 3552 5608 3897 5956 * 7137 84 145 3640 6028 830 1192 * * 6935 3497 0 R 85 * * 4843 3514 * 1840 5163 5963 3088 * * 2152 * 3943 4948 4245 4272 * * 6672 85 269 2555 * 826 1198 * 0 6750 4598 1243 I 86 5082 * 6836 * 6225 * 4699 1838 * 3125 5608 5497 3991 5465 * 4095 3841 2253 * 4345 86 25 5890 * 0 * * 0 6750 1645 1243 S 87 4939 * 5384 4007 5360 * * 3083 2749 4085 5783 6384 * 3669 3279 4047 4979 2269 * 5661 87 30 5588 * 0 * 0 * 6750 1649 1243 A 88 6480 * * * 3737 * 6654 3448 3584 2288 4014 * * 5568 6794 6093 3605 2439 4052 3464 88 40 5190 * 327 2300 * * 6939 1958 0 H 89 4459 * 5574 4388 * 5304 3285 5501 2143 7134 5990 4861 * 3825 3219 3228 3284 4334 * 6038 89 69 4413 * 460 1874 * * 6939 2737 0 H 90 5869 * 4194 2693 6093 * 4173 3970 3360 5019 * 4259 5872 5094 3494 4092 2515 4144 * 4880 90 27 5773 * 653 1457 * * 6939 1686 0 V 91 * * * 6460 4253 * 5584 2987 6333 1527 5714 * 5855 * * * * 2407 6284 2380 91 22 6039 * 1035 966 * * 6939 1475 0 P 92 7206 * 3500 3016 * 6140 4589 * 4536 6952 * 3915 1547 3470 4318 3917 4917 5256 * * 92 0 * * * * * * 6939 0 0 N 93 6941 * 1832 3901 * 3332 * * 3373 * * 1501 * 4033 5781 * 6019 * * * 93 0 * * * * * * 6939 0 0 M 94 * * * * 3516 * 5801 3938 * 2795 856 * * * * 5212 5713 3525 * * 94 0 * * * * * * 6939 0 0 V 95 5680 * * 5072 * * * 2362 5452 3740 4845 6731 * 6697 3174 2794 4686 1686 * * 95 0 * * * * * * 6939 0 0 A 96 1558 * * * * * * 3790 * * * * 4447 * * * 5056 965 * * 96 0 * * * * * * 6939 0 0 T 97 3249 * 3958 2213 * 6643 * 6284 2680 3417 * 5251 * 3991 3796 4138 3526 4736 * * 97 0 * * * * * * 6939 0 0 E 98 3759 * 3841 2047 * 4386 4444 * 2742 * * 5119 * 4767 3966 2482 3997 * * * 98 0 * * * * * * 6879 0 0 C 99 * 0 * * * * * * * * * * * * * * * * * * 99 0 * * * * * * 6879 0 0 G 100 2936 * 5361 5574 * 868 5074 * 4585 * * * * 6603 * 2974 4319 5869 * * 100 0 * * * * * * 6850 0 0 C 101 * 0 * * * * * * * * * * * * * * * * * * 101 0 * * * * * * 6850 0 0 R 102 * * * * * * * * 3380 * * * * 3209 330 * * * * * 102 0 * * 0 * * * 4799 0 0 //