HHsearch 1.5 NAME c9atqB_ FAM FILE c9atqB_ COM /bmm/www/servers/phyre2/HH/hhmake -i c9atqB_.a3m DATE Sat Aug 30 10:17:44 2025 LENG 1047 match states, 1047 columns in multiple alignment FILT 22 out of 24 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 3.8 EVD 0.3144 -9.9974 SEQ >ss_pred CCCEEEECCCEEEEEEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEEEECCCCEEEEEEEECC HHHEEEEECCHHCCCCCCCCCCCCEEEEEEECCCEEEEEEECCEEECCCCCCEEEEEECCEEEEEEECCCEEEEECCCCCCCCCCEEEEEEEEEEEEEEE EEEEECCCCCCCCCCCEEEEEEEECCCEEEEEEEECCCEEEEEEECCCCHHHHHEEEECCCCCCCCEEECCCCEEECCEEEEECCCCCCCCCCCEEEECC CCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCEEEHHCCCCCCCCCCEEEECCCCCCCCCCC CCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCEEEEEEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCEEEECEEEEEEECC EEEEEEEEEEEEEEECCEEEEEECCCCEEEEEECCCCCEEEEECCCCCCEEEEECCCCCCCCEEEEEEECCCCCEEECCCEEEEEEEEEECCCCCEECCC CCCCCCCCCCEEEEEECCCCCCCCCEEECCEEEECCCEEEEEEEEEEEEECCCEEEEECEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCEEEEEEEEEEEECCEEEEEECCEEEEECC EEEEEECCCCCCCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCC >ss_conf 9410010231025542000341753000223210024663010255202122013557746665556378750576057635764146522789997075 3522112011110688766666647997630452479997043120123531168851534998861770358863656666330368856544320168 8630022223366664013667621020799998257427878852755033311100134578873213650442131589746677776431233056 5765322001345430255314564211033444564532222103432355456530442100146766010010124574321013014330135546 6553301232014557766531246762367610111014566552100148997525760344567422116773344688756412204025588621 6889999820112873725897237845677631576079995167774489973653554013355410234200002100123321323676311354 4450204541256764046777633130342685442157888789985435259961204508848999999999899899999999977775688999 9864200001223455676230010468667776414677776575422000123433762676788898898999999885124432035443352687 8876405011227889987999999999999999988888999999999999854899999999975020136778999999875444410145655667 9999999999999999999999999999989975010101534687689997034998189999975468759999865566638056741653898688 89993223125415764444997114899997303213644753369 >Consensus xxxxxxxxxxxxxxxxxxxxyypxxxxxxxxxxxxxxlxlxxxxxxxxxxxxxxxxxxxxxxxfxxxxxfxxxxxsxxvxgxxxxxxxxxxxxxxxxvxx xxxxxxxxcxxtxcxxpxxnxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxfxxxxxxxxxyxxxxxxxxxxxxxxxxxxxxxlxxlpxxxnxxxxx xxxxxxxxxxxxxxxxxxxxxvxxlxxxxxLlxydxNGtItxavdCdxspxxxLkCxxxsfxxxxGfYxxsxxxvxxxxtxvxxpxxxxxxxxxxxxxxx xxxxxxxxxRxxxsNcxxNxsslxsxxxfxsxxcxxvsxsxlxxlCvssvtxDxFxixxxxxxxlxpxxsgxlxxyNyxixxxxxxcxlaysxxnlnnxx xxnxnxxyxcxxxsxxgxxxxxxxxxxxxxxxxxCxxvxxxxxxxxxxxxxxxxxyxxgxxxxxxxxxxxxxxxxPxtvcxxxxxsxixxdxCvxYnIYG xtGxGiixxxnxxxxxxxxxxxxxxGxllxFknxxtgxiyxVxPCxxxxxxvvxxxxxxxxxxxxlxxxxxcsxxxxxxtxxgcxxxxxxxxxxxxCxxp xgxgxCxdxxxxxxxtxxxxxxxxxxxxxxxIxIPtnFtlsvtxEyiQxxxxkvsIDCaxYVCngnxrCxxLLxQYgsfCxxIexaLxxxxxlxdxxxxx xxssxxxxxxxxxxxxxgxfNfsxiLpxxxxxxxRSaIEDLLFdKVaDLxCAQyYNGImVLPgVvdxexmAmYTxsLxGgmaxggxTaaaxxaxaIPFax xvQaRlNylalttxVLxeNQkiiAnsFNxAignIqxgFxtvsxALxKIQdVVNxqxxALxxLxxQLsnNFgAISSSixdIyxRLDxleAdaQVDRLItGR LxALnayVtQxLxxxxevraSrxLAxqKiNECVKSQSxRygFCGNGtHixSlxQxAPnGixFlHxxlvPtxxvxVxaxxGlCvxxxxxxxkxgxfvxxnx xxxxTxrxxYxPrxxtxxdxvxxxsCxvxxxxvxxtxxxpxqpxxxx >c9atqB_ QCVNLITRTQSYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSRFDNPALPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNN ATNVVIKVCEFQFCNDPFLDVMESEFRVYSSANNCTFEYVSQPFLMDKNLREFVFKNIDGYFKIYSKHTPINLERDLPQGFSALEPLVDLPIGINITRFQ TLLALHRSYLSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFHEVFNAT TFASVYAWNRKRISNCVADYSVIYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNKLDSKP SGNYNYLYRLFRKSKLKPFERDISTEIYQAGNKPCNGVAGPNCYSPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNG LTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVNVFQTRAGCLIGAEYVNNSYECDIP IGAGICASYQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLKRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKYFGGFNFSQILPDPSKPSKRSPIEDLLFNKVTDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGPALQIPFPM QMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTPSALGKLQDVVNHNAQALNTLVKQLSSKFGAISSVLNDILSRLDPPEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDS >UniRef50_A3EXG6(104-1142:1274) Spike protein S2 n=4 Tax=Rousettus bat coronavirus HKU9 RepID=SPIKE_BCHK9 E=0 s/c=0.88 id=35% cov=87% ---------------------------------------------------------------------------------------------------N QTNIYLLVCsNATLCINPGFNrwgPAGSFIAPDALVDHSNSCFVNNTFSVNISTSriSLAFLFKDGDLLIYHSGwlPTSNFEHGFSRGSHPMTYFMSLPV GGNLPRAQFFQSIVRSNAIDKGDGMCTNFdvnlhVAHLINRDLLVSYFNNGSVANAADCADSAAEELYCVTGSFDPPTGVYPLSRYRAQVAG-FVRVTQR GSYCT-PPYSVLQDPPQPVVWRRYMLYDCVFDFTVVVDSLPTHQLQCYGVSPRRLASMCYGSVTLDVMRINETHLNNLFNRVPDTFSLYNYALPDNFYGC LHAF---YLNSTAP------YAVANRFPIKPGGRQSNSAFIDT-------VINAAHYSPFS------------YVYGLAVITLKPAAGSKLVCPVANDTV VITDRCVQYNLYGYTGTGVLSKNTSLVIPDGkVFTASSTGTIIGV--SINSTTYSIMPCVTVPVSVGYHPNF---ERALLFNGLSCSQrsravtepvsvl wsasataQDAFDTPSGCVVNVELRNTTIvnTCAMPIGNSLCFINGSIATANADSLPrlqlVNYDPLYDNStatpmtpvywVKVPTNFTLSATEEYIQTTA PKITIDCARYLCGDSSRCLNVLLHYGTFCNDINKALSRVSTILDSALLSLVKelSINTRDEVTTFSFDGDYNFTGLMgclgPNCGATTYRSAFSDLLYDK VritdpgfmqsyqkcidsqwggsiRDLLCTQTYNGIAVLPPIVSPAMQALYTSLLVGAVASSGYTFGITSAGVIPFATQLQFRLNGIGVTTQVLVENQKL IASSFNNALVNIQKGFTETSIALSKMQDVINQHAAQLHTLVVQLGNSFGAISSSINEIFSRLEGLAANAEVDRLINGRMMVLNTYVTQLLIQASEAKAQN ALAAQKISECVKAQSLRNDFCGNGTHVLSIPQLAPNGVLFIHYAYTPTEYAFVQTSAGLCHNGTGYAPRQGMFVlpNNTNMWHFTTMQFYNPVNISASNT QVLTSCSVNYTSVNYTVLEPSVP---- >UniRef50_Q7TE91(243-1334:1481) S protein n=104 Tax=Coronavirinae RepID=Q7TE91_9ALPC E=0 s/c=0.65 id=25% cov=92% ---NAKTNYGYYVQFVNKTTYY---TYNNTGGTGVNQLQLGLCEDdfcAGYVTNVFTPVNGKIPGDFSFNNWFLLSDKSTIVQGRVV-SSQPVYVECLRP VPSWSNnsAIVSFDNDTFCPQAsadvlrfNLNFSGEVFHPNATADDQIIFTFEDNSTAEIScynganvTDPTIGFNTTSQIPFGGTADPYLCFVNFSTAA LDNQFLGILPptiremafgrdgsIFINGYKYFNMPPIKSINFAISAVEYYGFWtIAYTKYTDVMV--DVNGTsITRLFYCD-SPLNRIKCQQMKHELPDG FYSANSlVKKNLPKTFVTTPQFYNgmNVTLHVILNDTSAGTkVVGFERYELEQ--------IADILFEIPQNQDGEVKNVTNFCVQTRQLAFFFKYTSLQ GLYSISNTVWLKNY-----------DCPFSPQQFNNYLQFE----TLCFDTNPSVAG---------------CKWAVMHSPIWNTQFATITVTYKEGAQI ----------TTMPKPQLGFRDVSFKVEGECTDYNIYGFQGTGIIRKTESKLVAG-LFYTSASGDLLAFKNSTTGEIFTVVPCDLTAQAAVINdeivGAI TSINQTDLFEFVNHTHtvrrvrraVQTGTTITAYSMPQFYYITKWNNDTSENCTSVITYSSfaicntgeikFVNVTKVEAVEDGIgtvkPISTGNITIPK NFTVAVQAEYIQIQVKPVVVDCAKYVCNGNNHCNRLLTQYTSACQNIENALN-LGARLESLMLN--EMITVSDSSLELATIEKFNTTVVGGEklggiyfd glkdvlPAQPGGRSAIEDLLFNKVvtsglgtvdedykkcsagtdiADLVCAQYYNGVMVLPGVVDDNKMAMYTASLIGGMAMGSITSA----VAIPFAMQ VQARLNYVALQTDVLQENQKILANAFNNAMGNItlalgqvsdaistvSEGFNTMASALTKIQSVVNQQGNALSQLTQQLQNNFQAISSSIAEIYNRLEKV EADAQVDRLITGRLAALNAYVAQTLTQYTEVKASRQLAMEKVNECVKSQSDRYGFCGNGTHLFSLANAAPDGLLFLHTVLLPTEWEEVTAWSGICVNDtY AYVLKDfkSSIFSYSGTYMITPRNMFQPRKPQMSDFVQITSCEV------------------- >UniRef50_B2BW33(451-1300:1472) Spike protein n=1 Tax=Beluga Whale coronavirus SW1 RepID=B2BW33_9GAMC E=0 s/c=0.84 id=27% cov=72% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- --------------------FISTLNYTTALVTFD-KGNVRSVIDCNSEkPFDRLRCDLQTDVVSDGFYPVNikTNEAKENTTFIDVPATLANLTLEVFV SSPEQSPACVIKSYKCVDTRYFYISDYSYSCAE-----NGIPNDAAGAAYCRGVLDQ------------------INNYGVRGMDFKGKCPFAGSKVNSG LT-----------FDKICFGVYEQGCQS----------DKACRFGFYFdnvQFSQYG----NKLYYKPQDLGFIDYQFGTLFKNSL---VQSNIIQEGCH DYDIYGYKGTGVVKPFSdySYLQTGGLIMLDSGGFPSLFR--YNFALYEVTQCtrevaqlavasnnaigYYLPKQVTIDGVNASTSCNTTGAFKYCYYDD VIH------VGRDVSNVTINVCNPslmMENSHCINIQGNFMVNEPAITFNSTQYQPllgvsGDVQLPRTLMLHTTTEFIQTHSPKIVIDCTKYVCGSSER CRRILVKYGGFCESIMRLLNGVNMADDVSVtdfLDNFNSFDNISVSLqnlnaSFGQFEGYGFQKFLPKSFDFDGsdprdaRSTIEDILFDKvttvglgtv dadydkctkglsVADLVCAQYYNGIMVLPGVADAEKMAMYTGALVGGMVLGGITSAA----AIPFATQIQARVNYLALTQNAIQENQKIIVQQFNKAIDS MTsafqsvnEGFSAVSSAITEVQNAVNAQSQALTKLLGQLNYNFGATTSSIKELYERLAKLEADVQVDRLINGRLTALSAFVAARQVEAAKVASQRVLAA EKINECVKSTSNRYGFCGNGAHIISFPQNAPNGMLFVHFSLVPNETITVKGIIGLCLNNSIGivpAKDRGMFIQCSN-------GTYCPEFENSFNESKN GNVTFPFAITSREQYNPRQ----- >UniRef50_B3FHU5(157-1055:1226) Spike n=17 Tax=Coronavirinae RepID=B3FHU5_CVTKE E=0 s/c=0.76 id=30% cov=70% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- --------------------------------------------------INKLRCAYQQFNFSTGFYDIDTFVpVTSNITYLPYPDLKDNtgqevCDFY VALKGDHV--------------IYNQSCVDSKYPFFKLKCNNTYSWDNDKLCIlgSEIYVPGYNVYTNTQ-----------HSYAGTIPNYPTCSSKGLS LENIYNNIGFNRFCVTKLLTT-------RDISSIT----QYTCVYVVSVEGFDSYNQGIVYSYVGV----------NFDFGTAMYSV-KTAPMQFIYTEQ CHKYNIYNIRGVGQILNVTgkdNTTLVDGGLVITSGSGLLAFRN--NGSLFSVQPCRTVSTQAVI----VNGSFVGLFVPASCwladqfnlgNHTEYVDG --GCLISNKTISRKRRSTNAVYTGECTGLFAAMGTSCIYSngtvlnrtlPQPSVQTSVQpllgvvaNVSIPKELTLAVTTEYLQTRYQKVTIDCAKYVCG DSTRCRTLLQQYGSFCQSVNAILSGVNENEDNGLLQYAEAINTGYTLNFTGYNvsnlGGFDLSLVLPKNltlAQNQGRSTIEDLLFDKVvtlgvsevdqn ydkciasrggsftnlADLTCAQFYNGVMVLPGVVDPGLMAVYTGSLIGGMALGGITAAAS----IPFATQIQARVNYLALTQSVLLDNQNLIANSFNKAL KGIQSaldtvsqgfvevarGFESVTVALNKVQDVVNTHSDILNKLMAQLSVNFGAVSSSLNEIYLKLDQINADAQVDRLITGRLTALSTYVASLQLAAYK ADQSRRLALQKVEECVKSQSMRYGFCGNGSHVLTIPQSAPNGIFFIHYTYQPTSYVTIEAVPGLCVTTpsgkYGVMPKtgSGIIFRQNDTFFVTSTQLYE PKLLSYSEVVNLTSCEANYYNVSES-ETPFQPAL-- >UniRef50_Q8BB25(67-1226:1349) Spike protein S2 n=85 Tax=Betacoronavirus RepID=SPIKE_CVP67 E=0 s/c=0.85 id=33% cov=93% --------------------YYPisGATFRNMALKGTRLL------STLWFKPPFLS-------PFNDGI-FAKVKNSRFSKDGVIYSEFPAITIGSTFV NTSYSIVvephtslingnlqgllqISVCQYTMCEYPHTichpNLGNQRIELWHYDTDVVSCLYRRNFTYDVNADylYFHFYQEGGTFYAYFTDTGF---- -------VTKFLFKLYLGTVLSHYYVMPLTCNSALS------LEYWVTPLTTRQFLLAFDQDGVLYHAVDCASDFMSEIMCKTSSITPPTGVYELNGYTV QPVATVYRRIPDLPNCDIEAWLNSKTVSSPLNWERKIFSNCNFNMGRLMSFIQADSFGCNNIDASRLYGMCFGSITIDKFAIPNSRKVDLQVGKSGYLQS FNYKIDTAVSSCQLYYSlpaaNVSVTHYNPSSWNRRYGFNNQSfgsrglhdavysqqcfntpntycpcrtsqciggagtgtcPVGTTVRKCFAAVTKATK CTCWCQPDPSTYKGVNAWTCpqsKVSIQPGQHCPGLGLVEDDCSGNPCT-CKPQAfigwssetclqngrcnifanfilndvnsgttcstdlqqgNTIITT DVCVNYDLYGITGQGILIEVNATYYNsWQNLLYDSSGNLYGFRDYLSNRTFLIRSCYSGRVSAVFHAN--SSEPALMFRNLKCSHvfnntilrqiqlVNY FDSYLGCVVNAYNNTASAvsTCDLTVGSGYCVDYVTALrsrrSFTTGYRFTNFEPFAANlvndsiepvgglyEIQIPSEFTIGNLEEFIQTRSPKVTIDC ATFVCGDYAACRQQLAEYGSFCENINAILTEVNELLDTTQLQVANSlMNGVTLSTKIKDGINFnvddiNFSPVLGclgsECNRASTRSAIEDLLFDKVKl sdvgfvqaynnctggaeirDLICVQSYNGIKVLPPLLSENQISGYTLAATAASLFPPWTAAAG----VPFYLNVQYRINGLGVTMDVLSQNQKLIASAFN NALDAIQEGFDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISASLQEILSRLDALEAKAQIDRLINGRLTALNAYVSQQLSDSTLVKFSAAQAIEK VNECVKSQSSRINFCGNGNHIISLVQNAPYGLYFIHFSYVPTKYVTAKVSPGLCIAGDiGISPKSGYFINVNNSWMFTGSSYYYPEPITQNNVVVMSTCA V------------------- >UniRef50_A3EXD0(236-1223:1352) Spike protein S2 n=12 Tax=root RepID=SPIKE_BCHK5 E=0 s/c=0.90 id=36% cov=84% ---------------------------------------------------------------------------------------------------- -------------------------FKVYFDLINCTFRY-NYTITEDENAEWFGITQDTQGVHLYSSRKE-NVFRNNMFHFAT------LPVYQKILYYT VIPRSIRSPFNDRKAW-AAFYIYKLHPLTYLLNFDVEGYITKAVDCGYDDLAQLQCSYESFEVETGVYSVSSFEASPRGEFIE-QATTQECDFTPMLTG- TPPPIYNFKRLVFTNCNYNLTKLLSLFQVSEFSCHQVSPSSLATGCYSSLTVDYFAYSTDMSSYLQPGSAGAIVQFNYKQDFsNPTCRVLATVPQNLTTi TKPSNYAYLTECYKTSAYG----KNYLYNAPGAYTPCLSLASRGFSTKYQSHsdgeltTTGYIYPVTGNLQMAFIISVQYGTDTNSVCPMQALRNDTsie dkLDVCVEYSLHGITGRGVFHNCTSVGLRNQRFVYDTFDNLVGYHSD-NGNYYCVRPCVSVPVSVIYD--KASNSHATLFGSVACSHVTTmmsqfsrmtk tnllarttpgpLQTTVGCAMGFINSSMVVdECQLPLGQSLCAIPpttssrvrratsgasdvfqIATLNFTSPLTLAPINSTGFV-VAVPTNFTFGVTQEF IETTIQKITVDCKQYVCNGFKKCEDLLKEYGQFCSKINQALHGANLRQDESIANLFSSIKTQNTQPlQAGLNGDFNLTMLqIPQVTTGERkyRSTIEDLL FNKVTiadpgymqgydecmqqgpqsarDLICAQYVAGYKVLPPLYDPYMEAAYTSSLLGSIAGASWTAGLSSFAAIPFAQSIFYRLNGVGITQQVLSENQ KIIANKFNQALGAMQTGFTTTNLAFNKVQDAVNANAMALSKLAAELSNTFGAISSSISDILARLDTVEQEAQIDRLINGRLTSLNAFVAQQLVRTEAAAR SAQLAQDKVNECVKSQSKRNGFCGTGTHIVSFAINAPNGLYFFHVGYQPTSHVNATAAYGLCNTenpQKCIAPIDGYFVLNQTTstvadsdqqWYYTGSS FFHPEPITEANS--------------------------- >UniRef50_B6VDW0(74-1021:1165) Spike glycoprotein n=3 Tax=Avian coronavirus RepID=B6VDW0_9GAMC E=0 s/c=0.81 id=31% cov=68% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------------------------NTTITNVTYCDRSTLDMLACQISKHYVDDGFYSDpQKTSLALPRTIVTLPKVAEL----EMVNL TINARYSAGEASATININGNDTFCVTKPYFHINAKYTCSD------CVLNLRTDT--------------CSFDINAINNGMSFSQFCLSTKSGSCSITLV ATKYWN--------------------------------------------------YQIAQKLYVTAIEGQTSTGTTATSAQAIDSSNIVTDVCTDYTIY GVSGTGIITHSDLELHNGIAFTSPT-GELFAFKNTTSGKSFQVTPCDSPAQLVVV-----SNTIVGAITSNNISSTGKFTRTIAASTFYYSTNaTNLTCT EPVLSygpvSVCSDGAIAETSFLQDSRPSIVSLYDGEVEVPSAFTLSVQTEYLQVQSEQVVVDCARYVCNGNARCTRLLSQYTSACSNIESALHSSAQLD SREITNMFQTSSQSLTLANISNFqSDYNFTNIIT--SKSGGRSAIEDLLFNKVvtnglgtvdqdykacskdlaiADLVCTQYYNGIMVLPGVVDAQKMAM YTASLTGAMVFGGMTAAA----AIPFSTAVQARLNYVALQTNVLQENQKILAESFNSAVGNISLALSAVNDaikqtseslltvatAINKIQTVVNSQGEA LSHLTAQLSNNFQAISTSIQDIYNRLDEVQADQQVDRLITGRLAALNAYVTQLLNQMSQIRQSRLLAQQKINECVKSQSSRYGFCGNGTHLFSLTQSAPN GIFFMHAVLVPQQFTRVNASAGICVDAIKGYSLQPQLIlyQYNNSWRVTPRNMYEPRVPRAADFIPLVDCSV------------------- >UniRef50_P05135(208-1021:1163) Spike protein S2 n=1237 Tax=Avian coronavirus RepID=SPIKE_IBV6 E=0 s/c=0.91 id=28% cov=72% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -------------------------------LAYFVNGTAQDVILCDGSPTGLLACQYNTGNFSDGFYPfTNSSLVKEKFIVYRESSVNTTLELT----- -------NFTFSNVSNATPNTGGVQTIQLYQTI----TAQSGYYNLNFSFLSSFIYKASDYMYGSYHPSCKFRLETINNGLWFNSLSVSLGYGPIQGGCK QSVFANRATCCYAYSYNGP--------------SLCKGVYRGELTKSFECGLLVFVTKTDGS-------RIQTRNEPFTLTQHNYN-NITLDRCVEYNIY GRVGQGFITNVTNYAINYNYLadggmaILDTSGAIDIFvvQGEYGLNYYKVNPCEDVNQQFVVSGgklvgiltsrNETGSQPleNQFYIKIINGTRRSRR SITGNVTNCPYVTYGKFCIKPDGSISTIVPKELEHFVAPLLNV------TENVLIPDSFNLTVTDEYIQTRMDKVQINCLQYVCGNSLECRKLFQQYGPV CDNILSVVNSVGQKEDMELLYFYSSTKPSGFNTPVLSNvstGEFNISLLLTPPSSASGRSFIEDLLFTSVesvglptddaykkctagplgflKDLACARE YNGLLVLPPIITAEMQTLYTSSLVASMAFGGITSA----GAIPFATQLQARINHLGITQSLLFKNQEKIAASFNKAIGHMQEGFRSTSLALQQIQDVVNK QSSILTETMASLNKNFGAISSVLQDIYQQLDSIQADAQVDRIITGRLSSLSVLASAKQAEYYRVSQQRELATQKINECVKSQSIRYSFCGNGRHVLTIPQ NAPNGIVFIHFTYTPESFVNVTAIVGFCVNpanasQYAIVPANgrGIFIQVNGSYYITARDMYMPRDITAGDIVTLTSCQANYVSVNKTV---------- >UniRef50_A8JP00(132-992:1128) Spike glycoprotein n=3 Tax=Rhinolophus bat coronavirus HKU2 RepID=A8JP00_9ALPC E=1e-179 s/c=0.73 id=29% cov=68% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ----------------------------------DQSGAVTRYSYCADGFVNGLQCKLRLFDIPPGVYSNSEVEY-PVALYTVVHNMSVCPQRPESYCGS NYCP---FKRVVFSNCVVNYTSW---------------------------------------------TSGLLRDYQHLV------------------LP NGKFNPFTECNGLNRIVDDCVTGFVLRVGRGTAVNRTVITPYL-KPNECFG-WSWNDYQDSIYDWWIADFVSTGAFVCEKNPDAPR---TGVCITYTIEK VTFQGVLYESNFTFAQYYNVLY--FGSQLKYVRIL-GKVYEVAPCFEASYDVLF---RSSSSFGLLYRSFDCNQLrisasrfaerllpshNGTATALGCL FNATYAPNDtmVNCTNPLGDGFCADLLSnVVVRRMTFEKHDTTYVAPVTIerftELPLDHQLVLTEQFLQTTMPKFSISCETYICDVSKACKNLLFRYGG FCQKIEADIRGAGVLLDSDVSGLYSTIAAKTSS-IMPTTDRFNVSQfFLPKVQstseRFESRSVIEDLLFSKiettgpgfygdyynckknaIQDLTCAQY HNGILVIPPVMDAETLGMY-----GGIAAASLTLGIfgGQAGITTWSLAMAGRLNALGVVQNALVDDVNKLANGFNQLTASVSKLALTTSSALQAIQAVV NQNAAQVESLVSGITENFGAISTNFKVISQRLDKLEADVQMDRLINGRMNVLQLFVTNYKLKIAELRNTHRYVQSLINECVYAQSLRNGFCGQGLHVLSL MQNAPSGIMFFHYSLIPNNTIIVKTTPGLCESDelgsKCIVAKDGVLVSANLSyWQWSPRNLYKPENLTFANVIAVS----------------------- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * Q 1 * * * * * * * * * * * * * 0 * * * * * * 1 0 * * * * * * 1000 0 0 C 2 * 0 * * * * * * * * * * * * * * * * * * 2 0 * * * * * * 1000 0 0 V 3 * * * * * * * * * * * * * * * * * 0 * * 3 0 * * * * * * 1000 0 0 N 4 * * * * * * * * * * * 0 * * * * * * * * 4 0 * * * * * * 1624 0 0 L 5 1092 * * * * * * * * 914 * * * * * * * * * * 5 0 * * * * * * 1624 0 0 I 6 * * * * * * * 914 1092 * * * * * * * * * * * 6 0 * * * * * * 1624 0 0 T 7 * * * * * * * * * * * * * * * * 0 * * * 7 0 * * * * * * 1624 0 0 R 8 * * * * * * * * * * * 1092 * * 914 * * * * * 8 0 * * * * * * 1624 0 0 T 9 * * * * * * * * * * * * * * * * 914 * * 1092 9 0 * * * * * * 1624 0 0 Q 10 * * * * * 1092 * * * * * * * 914 * * * * * * 10 0 * * * * * * 1624 0 0 S 11 * * * * * * * * * * * * * * * 914 * * * 1092 11 0 * * * * * * 1624 0 0 Y 12 * * * * * * * * * * * * * * * * * * * 0 12 0 * * * * * * 1624 0 0 T 13 * * * * * * * * * * * * * * * * 914 1092 * * 13 0 * * * * * * 1624 0 0 N 14 * * * * * * * * * * * 914 * 1092 * * * * * * 14 0 * * * * * * 1624 0 0 S 15 * * * * 1359 * * * * * * * * * * 713 * * * * 15 0 * * * * * * 1760 0 0 F 16 * * * * 1704 * * * * * * * * * * 1721 * 1359 * * 16 0 * * * * * * 1760 0 0 T 17 * * * * * * * * * * 1721 1359 * * * * 1704 * * * 17 0 * * * * * * 1760 0 0 R 18 * * * * * * * * 1359 * * * * * 713 * * * * * 18 0 * * * * * * 1760 0 0 G 19 * * * * * 713 * * * * * * * * * * 1359 * * * 19 0 * * * * * * 1760 0 0 V 20 * * * * * * * * * * * * * * * * 1359 713 * * 20 0 * * * * * * 1760 0 0 Y 21 * * * * * * * * * * * * * * * * * * * 0 21 0 * * * * * * 2326 0 0 Y 22 * * * * * * * * * * * * * * * * * * * 0 22 409 * 2018 * * * * 2326 0 0 P 23 * * * * * * * * * * * * 0 * * * * * * * 23 1031 969 * 1000 1000 * 0 1908 1291 1000 D 24 * * 1031 * * 969 * * * * * * * * * * * * * * 24 0 * * * * * 0 1908 0 1000 K 25 1951 * * 2014 * * * * 2049 * * * * * * 1988 * * * * 25 0 * * * * 0 * 1908 0 1000 V 26 * * * * * * * 2432 * * * 2407 * * * * 1173 2453 * * 26 0 * * * * * * 2326 0 0 F 27 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2326 0 0 I 52 * * * * * * * 1442 * * * * 1377 * * * * 2018 * * 52 0 * * * * * * 2326 0 0 H 53 * * * * 662 * 2453 * * * * 2432 * * * * * * * * 53 296 * 2432 * * * * 2326 0 0 V 54 * * * * * * * * * 1187 * * * * * * 1848 1822 * * 54 0 * * * * 0 * 2220 0 1000 S 55 * * * * * * 2432 * * * * * 2018 * * 817 * * * * 55 316 * 2347 * * * * 2326 0 0 R 56 * * * 1870 * * * * * * * * * * 2193 * 2184 1798 * * 56 461 * 1870 * * * 0 2141 0 1000 F 57 * * * * 713 * * * * * * 1359 * * * * * * * * 57 0 * * * * * 0 1760 0 1291 D 58 * * 1704 * * 529 * * * * * * * * * * * * * * 58 0 * * * * * 0 1760 0 1291 N 59 * * * * * * * * 1359 * * 713 * * * * * * * * 59 0 * * * * * 0 1760 0 1291 P 60 * * * * * * * 1359 * * * * 713 * * * * * * * 60 0 * * * * * 0 1760 0 1291 A 61 1704 * * * * * * * * * * * 1359 * * * * 1721 * * 61 0 * * * * * 0 1760 0 1291 L 62 * * * * * 1359 * 1721 * 1704 * * * * * * * * * * 62 0 * * * * 997 1003 1760 0 1291 P 63 * * 1804 * * * * * * * * * 487 * * * * * * * 63 0 * * * * 0 * 2177 0 1000 F 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* * * * 88 0 * * * * * 0 2447 0 1000 D 89 * * 2496 * * * * * * * * 2487 634 * * * * * * * 89 0 * * * * 0 * 2447 0 1000 S 90 2572 * * * * * * * * 2448 * 2688 * * * 1670 * 2480 * * 90 0 * * * * * * 2586 0 0 K 91 * * * * * * * 2572 1702 2448 * * * * * * * * * 1551 91 0 * * * * * * 2586 0 0 T 92 * * * * * * * * * * * * * * * 2688 1052 1464 * * 92 0 * * * * * * 2586 0 0 Q 93 * * * 2480 * * * 2572 * * * 2448 * 1702 * * * 2626 * * 93 0 * * * * * * 2586 0 0 S 94 * 1464 * * * 2572 * * * * * * * * * 1702 * 2626 * * 94 0 * * * * * * 2586 0 0 L 95 * * * * * * * * * 563 * * * * * 2572 * 2688 * * 95 0 * * * * * * 2586 0 0 L 96 * * * 2626 * * * 2688 * 2716 * * * * 2480 * 2572 * 2448 * 96 0 * * * * * * 2586 0 0 I 97 * * * * 2572 * * 1702 * * * * 931 * * * * * * * 97 0 * * * * * * 2586 0 0 V 98 * * * * * * * 2688 * * * * * * * * * 550 * 2626 98 0 * * * * * * 2586 0 0 N 99 * * * * * * * * * * * 650 1464 * * * * * * * 99 0 * * * * * * 2586 0 0 N 100 * * * * * * * * * * * 862 * * * 1685 2846 * * * 100 0 * * * * * * 2827 0 0 A 101 2988 * * * 2661 * * 2892 * * * * * 2636 * 1902 * * 2710 * 101 209 * 2892 * * * * 2827 0 0 T 102 * * * * * 2525 * * * * * * * * * 2552 1097 * * 2410 102 0 * * * * * 0 2716 0 1000 N 103 * * * * * * * * * * * 648 * * * 2410 * 2525 * * 103 270 2552 * 1000 1000 0 * 2716 1000 1000 V 104 1685 * * * * * * 1202 * * * * * * * * * 1974 * * 104 0 * * * * * * 2827 0 0 V 105 2661 * * * * * * 2710 * * 2892 * * * * * * 1345 * 2636 105 216 2846 * 4087 87 * * 2827 1000 0 I 106 2892 * * * * * * 1345 * 2636 * * * 2661 * * * 2710 * * 106 0 * * * * * * 2827 0 0 K 107 * * * * * * * * 2988 2636 * * * 2661 2961 1229 * * * * 107 0 * * * * * * 2827 0 0 V 108 2961 * * * 1685 * * * * * * * * * * * * 835 * * 108 0 * * * * * * 2827 0 0 C 109 * 239 2710 * * * * * * * * * * * * * * * * * 109 554 1649 * 1279 766 * * 2827 1598 0 E 110 * * * 2988 * * * * * * * 1177 * 1751 * * 2892 * * * 110 0 * * * * * * 2827 0 0 F 111 2636 * 2710 * 1277 * * * * * * * * * * * * * * 1869 111 0 * * * * * * 2827 0 0 Q 112 * * * 2961 * * * * * * * * * 2988 * 2661 767 * * * 112 0 * * * * * * 2827 0 0 F 113 * * * * 1842 * * 2892 * 1789 2846 * * 2661 * * * * * * 113 0 * * * * * * 2827 0 0 C 114 * 0 * * * * * * * * * * * * * * * * * * 114 0 * * * * * * 2827 0 0 N 115 * * 2961 2846 * * * 2636 * * * 1815 2710 2892 * * * * * * 115 0 * * * * * * 2827 0 0 D 116 * * 2988 * * 2661 * * * 2892 * 1789 * 2710 * * * * * 2846 116 0 * * * * * * 2827 0 0 P 117 2710 * * * * * * * * * * * 537 * * * * 2661 * * 117 239 2710 * 2807 222 * * 2827 1000 0 F 118 * * * * 1974 2636 2846 * * * * 2710 * * * 2661 * * * 2892 118 209 * 2892 * * * * 2827 0 0 L 119 * * * * 1622 * * * * 1038 * * * * * * 2410 * * * 119 301 2410 * 2000 415 * 0 2716 1000 1000 D 120 2793 * 2807 * * * * * * * * 488 * * * * * * * * 120 287 2470 * 1585 585 * 0 2716 1000 1000 V 121 * * * * 2552 * * * * 2410 * 2525 2470 * * * * 1800 * * 121 225 2793 * 2322 322 * 0 2716 1000 1000 M 122 2470 * * * * 2410 * * * * 2807 * * * * 2552 1653 * * * 122 0 * * * * * 0 2716 0 1000 E 123 * * * 2807 * 1510 * * * * * 2410 * 2793 * * * 2525 * * 123 0 * * * * 0 * 2716 0 1000 S 124 * * 2661 2710 * * * * * * * * * 2846 * 1801 1926 * * * 124 0 * * * * * * 2827 0 0 E 125 * * * 2988 2636 * 2961 * * * * * 2892 * 2846 * * 1685 * * 125 0 * * * * * * 2827 0 0 F 126 * 3105 * * 1403 * * 1337 * * * * * * * * 3186 * * * 126 0 * * * * * * 3010 0 0 R 127 2842 * * 3074 * * 2902 * 1981 * 3186 * * * 2030 * * * * * 127 0 * * * * * * 3010 0 0 V 128 * * * * 2861 * * 3186 * 3074 * * 1360 * * * * 2033 * * 128 0 * * * * * * 3010 0 0 Y 129 * * 2842 * 3186 * * * * * * 1367 * * * * * * 3074 2033 129 0 * * * * * * 3010 0 0 S 130 1872 * 3186 * 2867 * 3074 * * 2861 * * * * * 3221 3105 * * * 130 0 * * * * * * 3010 0 0 S 131 * * 2867 * * * * * * 2842 * 1459 * * * 3221 2902 * * 3074 131 0 * * * * * * 3010 0 0 A 132 1511 * 3074 * 2861 3105 * * * 2867 * * * * * * * 2842 * * 132 0 * * * * * * 3010 0 0 N 133 * * 1872 * 3186 * * 2867 * * * 2162 * * * * 1964 * * * 133 214 2861 * 3807 107 * * 3010 1000 0 N 134 * * 1986 * * * 2842 * * * * 1024 * * 3105 * * * * * 134 0 * * * * * * 3010 0 0 C 135 * 1498 * * * * * * * * * * * 2902 * 2842 2861 2089 * * 135 0 * * * * * * 3010 0 0 T 136 * * * * * * * 2000 * * * 2842 * * * * 1024 3074 * * 136 0 * * * * * * 3010 0 0 F 137 * * * * 1498 1978 * 2902 * * * * * * * 1953 * * * * 137 0 * * * * * * 3010 0 0 E 138 * 1953 * 2204 2000 2861 * * * * * * * * 2867 * * * * * 138 0 * * * * * * 3010 0 0 Y 139 * * * * 2842 * * * * 3074 * * * * * * 2902 2861 3105 1498 139 421 3105 2867 1585 585 * * 3010 1000 0 V 140 * * * * 2710 * * 1803 * * * * * * * * * 1246 * 2846 140 0 * * * * 0 * 2827 0 1000 S 141 * * * 2902 * * * * 3105 2861 * 1854 * * 3074 2204 * * * * 141 0 * * * * * * 3010 0 0 Q 142 * * 2037 2861 * * * * * * * 2842 3105 3221 3074 * * * * 2867 142 0 * * * * * * 3010 0 0 P 143 3186 * * * * * * 2861 * * * 1986 2162 * * * 1854 * * * 143 0 * * * * * * 3010 0 0 F 144 * * * * 1073 * * 1981 * * * * * * * 1882 * * * * 144 0 * * * * * * 3010 0 0 L 145 * 1978 * * * * * * * 3221 * * * * * 2004 1360 * * * 145 0 * * * * * * 3010 0 0 M 146 2902 * * 2867 * * * * * 2145 3221 * * * * * * 2842 * 1964 146 0 * * * * * * 3010 0 0 D 147 * * 1080 2902 * * * * * 3105 * 1852 * * * * * * * * 147 168 3186 * 3000 193 * * 3010 1000 0 K 148 * * 2861 2867 * * * 1872 1585 * * * * * * * * 3074 * * 148 178 * 3105 * * * * 3010 0 0 N 149 * * * * * * 3041 * * * * 1222 * * * 1734 2746 * * * 149 230 2765 * 2807 222 * 0 2921 1000 1000 L 150 1694 * * * * * * * * 2052 * * * * * * 1734 2746 * * 150 0 * * * * 0 * 2921 0 1000 R 151 * * 1986 2867 * * * * * * * * * * 1585 1852 * * * * 151 431 1953 * 1000 1000 * * 3010 1537 0 E 152 * * * 1495 * * * * * * * 3105 2902 * * 2842 * * 2867 3074 152 0 * * * * * * 3010 0 0 F 153 * * * * 763 * * * * 2842 * * * * * 2861 2902 * * * 153 0 * * * * * * 3010 0 0 V 154 2842 * * * * 2867 3074 2902 * * * * * * * 2861 3105 2204 * * 154 0 * * * * * * 3010 0 0 F 155 * * * * 456 2902 * 2867 * * * * * * * * * * * * 155 178 * 3105 * * * * 3010 0 0 K 156 * * * * 2765 * * * 2052 2703 * * * * * * 2715 * * 1709 156 0 * * * * 0 * 2921 0 1000 N 157 * * * * 2842 * * * * * * 1098 * 1967 * 2861 * * * * 157 0 * * * * * * 3010 0 0 I 158 * * 2867 3074 * * * 3221 2004 * * * * * * * 2902 3105 * 2861 158 214 * 2861 * * * * 3010 0 0 D 159 * * 1309 * * 2894 * * * * * 2924 * * * * 1599 * * * 159 0 * * * * 0 * 2805 0 1000 G 160 3105 * * * * 706 * * * * * * * 2867 * 2902 * * * * 160 178 3105 * 1585 585 * * 3010 1000 0 Y 161 * * 2842 2861 3186 2867 * * * * * * * 2902 * * 3074 * * 2162 161 0 * * * * * * 3010 0 0 F 162 * * * * 1547 * * 1882 * 2004 * * * * * * * 2867 * * 162 0 * * * * * * 3010 0 0 K 163 * * * * * * 1981 * 3221 2842 * * 2902 * * 2861 * * * 2129 163 0 * * * * * * 3010 0 0 I 164 3074 * * * 1367 * * 2019 * 2867 * * * * * * * 3186 * * 164 0 * * * * * * 3010 0 0 Y 165 * * * * * 1882 * * * * * * * * * * * * * 457 165 0 * * * * * * 3010 0 0 S 166 * * * * 3074 2902 2842 * 3186 * * * * 3105 * 2033 * 2861 * * 166 0 * * * * * * 3010 0 0 K 167 * * * * * 3186 * * 3221 * * * * 3105 * 1854 1358 * * * 167 178 3105 * 0 * * * 3010 1000 0 H 168 2902 * 1964 * * 1967 3221 * * * * * * * 2867 * * * * 3186 168 217 2842 * 1000 1000 * * 3010 1000 0 T 169 * * 2902 * * 2861 * * 2867 * * * 2842 3186 * * 1547 * * * 169 0 * * * * * * 3010 0 0 P 170 * * * 2867 3105 3074 * * * * * * 1034 * * * 2842 * * * 170 213 * 2867 * * * * 3010 0 0 I 171 * * * * 2846 * * 1974 * * * * * * 2661 2636 * * * 1798 171 216 * 2846 * * 0 * 2827 0 1000 N 172 2690 * 3042 * * * * * * 2767 * 1228 * * * * * * * 2740 172 0 * * * * * 0 2898 0 1000 L 173 * 1753 * * 2690 * * * * 3071 * * * * * * * 1865 * 2690 173 0 * * * * * 0 2898 0 1000 E 174 * * * 1868 1153 * * * * * * * * * * * * 3042 * 2690 174 0 * * * * * 0 2898 0 1000 R 175 1715 * * * * * 2690 * * * * * * * 1346 * * 2767 * * 175 234 * 2740 * * * 0 2898 0 1000 D 176 * * 1140 * * 2496 * * * * * 1438 * * * * * * * * 176 0 * * * * * 0 2683 0 1600 L 177 * * * * 1438 * * * 2495 1855 * 2497 * * * * * * * * 177 0 * * * * 1051 951 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