HHsearch 1.5 NAME c8z3wC_ FAM FILE c8z3wC_ COM /bmm/www/servers/phyre2/HH/hhmake -i c8z3wC_.a3m DATE Sat Feb 8 09:11:00 2025 LENG 1061 match states, 1061 columns in multiple alignment FILT 23 out of 25 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 3.8 EVD 0.3180 -9.4223 SEQ >ss_pred CCCCCCCCCCCCHHHHHHHCCEEECCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEECCEEEEEECCCCEEEEEEEECCCCCEEEEEEEE CCCCEEEEEEECCEEECCCCCCEEEECCCCCCEEEEEEEEECCEEEEEEECCCCEEECCCCCEEEEEEEEEECCEEEEEECCCEEEEHHCCCCCCEEEEE EEEEEEEEEEHHEEEECCCCCCCCCHHEEEEECCCEEEEEEEECCCEEEEEEECCCCHHHHHEEEECCCCCCCCCCCCCCCEEECCEEEEECCCCCCCCC CCEEECCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEE CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEEEEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCEEECC EEEEEEEEEEEEEEEEEEEEEEECCEEEEEECCCCEEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCCEECCCCEEEEEEC CCCCCEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEECCCEEEEEEEEEEEEECCCEEEEECEEECCCCHHHHHHHHHHHHHHHHHHHHH HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCEEEECCCCCHHHHHHHHHHHHHHHHCCCHH HHCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCEEEEEEEEEEEECCEE EEECCCEEEEECCEEEEEECCCCCCCCCCCCCEEEECCEEEEEEECCCHHCCCCCCCCCCC >ss_conf 9111122244772576431010221715541210001232121133232100233456777435553250687514760365267630565247788960 6530156654130220476651364067886504766543120156885036642312442035553577418579999678211100036764214678 9888766662120221125776657220367302307999995275278786437560444221103446788711256651102305898355677755 0102157656654332102553024552001210010554335666443433320126888999406640001346654321100103666676401223 1234552341046631022366655466543210014567776655046899975320123323467630023420126631676412456775102040 2568861068899998200127627169981588367886146760799953787634799616543431012201201111223310000220453202 6775223022355112555542146762113677642431136225334216788877998543525996220440884899999999989989999999 8855563677899998865302335423357764022126854666521567777656542211011353476267678889889899999988500001 0013334462787888751502232888998899999999999999999999999999999999985489999999997511124687899999999866 6520134655667899999999999999999999999999998997511110154468768999703499818999997546875999986566653806 6631863898588799953032264167644569970016999952501125333344589 >Consensus xxxxxxxxxxxxxxxxxxxxxxxyxpxxxxxxxxxxxxxxlxxxxxxxxxxxxxxxxxxxxxxipfxxxxxfxxxxxsxxvxgxvxxsxxxxxxxxlxxv xxxxxxxxxxcxxxxcxxxxxxxxxxxnxxxxxxxxxxxxxxxxnxxxxxxnxxxxxxxnxxxxxxfxxxxxxxxxxxxxxxxxxxxxxxlpxxxxxxxx xxxxxxxxnxxxxxxxxxxxxxxxxxxxxixxlxxxxxLLxydxNGtItxvvyCdxxxxxxLkCqxxsfxxxdGfYxxsxxxxxxxxxivxxPxxxxxcx xxxxlnxtxxxsxxxwerxxfsNcxxnxSxlxxxxxxxxxxcxxvxxxxxxxxCxxsxxxdxfxxxxxxxxxxxxxxxxxxxxxnYkxxxxxxxCxxxxx xxNnyltfxslxxslxxxxxxgxxkxsxxxxsxxixaxxxxxcxxxxxxxcxxxxxxxxxxxxxgvxyxxxtxxvxxxxixxxxxtvcgxxxxsxixxdx CvxYnIYGxtGxGvixxxnsxxxxxxxxxxsxsGxLxxFknxxtgxxyxVxPCxxxxqxvvxxxxxxgxxxaxxxxxvxxsxxxxxxxxtxxgcxxxxxx xxxxxxCxxPxgxgxCxdxxxxxxxxxxxxxxxxxxxxxxxxxnVxIPtnFtlsvtxEyiQxxxxkvsIDCxxYVCnxnxxCxxLLxqYgsfCxxIexaL xxxaxledxexxxmxxxxxxxxxlxxixxfxxxnfsxiLxxpxxxxgRSaIEDLLFxKVaDLxCAQyYNGImVLPgVvdxexmAmYTasLxggmxxggiT aaaxxaxxIPFaxxvQaRlNylalttxVLxeNQkiiAnsFNxAigxIqxgfxttsxALxKIQdVVNxqxxALxxLxxQLsxNFgAISSSixdIyxRLDxl eAdaQVDRLItGRLxaLnayVtqxLxxxxevrxsrxLAxqKINECVKSQSxRygFCGNGtHixSlxqxAPnGixFxHxxlvPtxxvxVxaxxGlCvxxxx xvxkxgxfvxxnxxwxiTxRxxYxPrxiTxxdxvxixsCxVxyxxvxxtvxxxxqpxlxxf >c8z3wC_ QCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEP LVDLPIGINITRFQTLLALSSSGWTAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCP FGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWN SNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNK CVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPSNVFQTRAGCLIGAEH VNNSYECDIPIGAGICASYQTSQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRAL TGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWT FGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKV EAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKA HFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSF >UniRef50_A3EXD0(211-1203:1352) Spike protein S2 n=12 Tax=root RepID=SPIKE_BCHK5 E=1e-156 s/c=0.56 id=36% cov=83% ---------------------------------------------------------------------------------------------------- ------------------------------------FKVYFDLINCTFRY-NYTITEDENAEW---FGITQDTQGVHLYSSRKE-NVFRNNMFHFATLPV YQKILYYTVIPRSIRSPFNDRKAW-AAFYIYKLHPLTYLLNFDVEGYITKAVDCGYDDLAQLQCSYESFEVETGVYSVSSFEASPRGEFIE-QATTQECD FTPMLTGTP-PPIYNFKRLVFTNCNYNLTKLLSLFQVSEFSCHQVSPSSLATGCYSSLTVDYFAYSTDMSSYLQPGSAGAIVQFNYKQDFSNPTCrVLAT VPQNLTTiTKPSNYAYLTECYKTSAYG--KNYLYNAPGAYTPCLSLASRGFSTKYQSHSDGELTTTGYIY-PVTGNLQMAFIISvqygtDTNSVCPMQAL RNDTSiedklDVCVEYSLHGITGRGVFHNCTSVGLRNQRFVYDTFDNLVGYHSDNGN-YYCVRPCVSVPVSVIY--DKASNSHATLFGSVACSHVTTMMs qfsrmtktnllarttpgpLQTTVGCAMGFINSSMVVdECQLPLGQSLCAIPPTTSSRVRratsgasdvfqiATLNFTSPLTLAPINSTgfvVAVPTNFTF GVTQEFIETTIQKITVDCKQYVCNGFKKCEDLLKEYGQFCSKINQALHGANLRQDESIANLFSSIK-TQNTQPLQAGLNGDFNlTMLQIPQVTTGerkyR STIEDLLFNKVTiadpgymqgydecmqqgpqsarDLICAQYVAGYKVLPPLYDPYMEAAYTSSLLGSIAGASWTAGLSSFAAIPFAQSIFYRLNGVGITQ QVLSENQKIIANKFNQALGAMQTGFTTTNLAFNKVQDAVNANAMALSKLAAELSNTFGAISSSISDILARLDTVEQEAQIDRLINGRLTSLNAFVAQQLV RTEAAARSAQLAQDKVNECVKSQSKRNGFCGTGTHIVSFAINAPNGLYFFHVGYQPTSHVNATAAYGLCNTenpQKCIAPIDGYFVLNQTtstvadsdqQ WYYTGSSFFHPEPITEANS---------------------------- >UniRef50_Q8BB25(67-1229:1349) Spike protein S2 n=85 Tax=Betacoronavirus RepID=SPIKE_CVP67 E=0 s/c=0.87 id=34% cov=94% -----------------------YYPisGATFRNMALKGTRLL------STLWFKP-------PFLsPFNDGI-FAKVKNSRFSKDGVIYSEFPAITIGS TFVNTSYSIVvephtslingnlqgllqISVCQYTMCEYPH--TICHPNLGNQRIELWHYDTDVVSCLYR---RNFTYDVNADYLY-FHFYQEGGTFYAYF TDT----------GF-VTKFLFKLYLGTVLSHYYVMPLTCNSALSLEYWVTPLTTRQFLLAFDQDGVLYHAVDCASDFMSEIMCKTSSITPPTGVYELNG YTVQPVATVYrRIPDLPN-CDIEAWLNSKTVSSPLNWERKIFSNCNFNMGRLMSFIQADSFGCNNIDASRLYGMCFGSITIDKFAIPNSRKVDLQVGKSG YLQSFNYKIDTAVSSCQLYYSLpaanvsvthynpsswnrrygfNNQSFGSRGLHDAVYsqQCFNTPNTYCPCRT-SQCIGGAGTGTCpvgttvrkcfaav TKATKCTCWcqpdpstykgvnawtCPQSKVSIQPGQhcpglglveddcsgnpctckpqafiGWSsetcLQNGRCNIFANFILNDvnSGTTCSTdlqQGNT IITTDVCVNYDLYGITGQGILIEVNATYYNsWQNLLYDSSGNLYGFRDYLSNRTFLIRSCYSGRVSAVFHAN--SSEPALMFRNLKCSHVFNNTilrqiq lvnyFDSYLGCVVNAYNNTASAvsTCDLTVGSGYCVDYVTAlRSRRSFTTGYRFTNFEPFAANlvndsiepvgglyEIQIPSEFTIGNLEEFIQTRSPKV TIDCATFVCGDYAACRQQLAEYGSFCENINAILTEVNELLDTTQLQVANSLMNGVTLSTkIKDGINFnvddiNFSPVLgclgSECNRASTRSAIEDLLFD KVKlsdvgfvqaynnctggaeirDLICVQSYNGIKVLPPLLSENQISGYTLAATAASLFPPWTAAAG----VPFYLNVQYRINGLGVTMDVLSQNQKLIA SAFNNALDAIQEGFDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISASLQEILSRLDALEAKAQIDRLINGRLTALNAYVSQQLSDSTLVKFSAAQ AIEKVNECVKSQSSRINFCGNGNHIISLVQNAPYGLYFIHFSYVPTKYVTAKVSPGLCIAGDIGIsPKSGYFINVNNSWMFTGSSYYYPEPITQNNVVVM STCAVNYTKAPDLMLNTSTPNLPDF >UniRef50_B2BW33(451-1334:1472) Spike protein n=1 Tax=Beluga Whale coronavirus SW1 RepID=B2BW33_9GAMC E=0 s/c=0.82 id=27% cov=72% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -------------------------PQTFISTLNYTTALVTFD-KGNVRSVIDCNSEkPFDRLRCDLQTDVVSDGFYPVN-------------------- ----------IKTNEAKENTTFIDVPATLANLTLEVFVSSPEQSPACVIKSYK-CVDTRY---FYISDYSYSCAENGIPNDAAGAAY--------CRGVL DQIN-NYGVRGM-DFKGKCPFAGSKVNSGLTFDKICFGVYEQGCQSDKACRFGFYFDNVQFsQYGNKLYYKPQDLGFIDYQF----GTLFKNSLvQSNII QEGCHDYDIYGYKGTGVVKPFSdySYLQTGGLIMLDSGGFPSLFR--YNFALYEVTQCTREVAQLAVASNNAIGyylPKQVTIDGVNAS-TSCNTTGAFK YCYyddvihVGRDVSNVTINVCNPslmMENSHCINIQGNFMVNEPAITFNSTQYQPLlgVSGDVQLPRTLMLHTTTEFIQTHSPKIVIDCTKYVCGSSER CRRILVKYGGFCESIMRLLNGVNMADDvsvTDFLDNFNSFDNISVSlqnlnASFGQFEGYGFQKFLPKSFDFDGsdprdaRSTIEDILFDKvttvglgtv dadydkctkglsVADLVCAQYYNGIMVLPGVADAEKMAMYTGALVGGMVLGGITSAAA----IPFATQIQARVNYLALTQNAIQENQKIIVQQFNKAIDS MTsafqsvnEGFSAVSSAITEVQNAVNAQSQALTKLLGQLNYNFGATTSSIKELYERLAKLEADVQVDRLINGRLTALSAFVAARQVEAAKVASQRVLAA EKINECVKSTSNRYGFCGNGAHIISFPQNAPNGMLFVHFSLVPNETITVKGIIGLCLNNSIGIVPAkdrGMFIQCSNgtycpefensfneskngnvtfPF AITSREQYNPRQITTGDIQMLTSCN--------------------- >UniRef50_Q7TE91(251-1333:1481) S protein n=104 Tax=Coronavirinae RepID=Q7TE91_9ALPC E=0 s/c=0.66 id=27% cov=91% --------------YVQFVNKTTYY---TYNNTGGTGVNQLQLGLCEDdfCAGYVTNVFTPVNGKIPgdFSFNNWFLLSDKSTIVQGRVV-SSQPVYVEC LRPVPSWSNnsAIVSFDNDTFCpqasadvlrfNLNFSGEVFHPNATADDQIIFTFEDNSTAeiSCYNGANVTdPTIGFNTTSQIPFGGTADPYLCFVNFS TAALDnqFLGILPPTIREMAFGRDGSIFINGYKYFNMPPIKSINFaisAVEYYgfwtIAYTKYTDVMV--DVNGTsITRLFYC-DSPLNRIKCQQMKHEL PDGFYSANSLvKKNLPKTFVTTPQFYNgmNVTLHVILNDTSAGTkVVGFERYELEQ--------IADILFEIPQNQDGEVKNVTNFCVQTRQLAFFFKYT SLQGLYSISNTVWLKNYD---------CPFSPQQFNNYLQFETLCF-----------------DTNPSVAGCKWAVMHSPIWNTQFATITVTYKEGA--- -----------QITTMPKPQLGFRDVSFKVEGECTDYNIYGFQGTGIIRKTESKLVA-GLFYTSASGDLLAFKNSTTGEIFTVVPCDLTAQAAVINdeiv GAITSINQTDLFEFVNHTHTVRRVRRAvQTGTTITAYsmpqfyyitkwNNDTSENCTSVItysSFAICNTGEIKFVNVTKveAVEDGIGTVKPISTGNIT IPKNFTVAVQAEYIQIQVKPVVVDCAKYVCNGNNHCNRLLTQYTSACQNIENALNLGARLESLMLNEMITVSDSSLELATIEKFnttvvggeklGGIYFD GLKDVlPAQPGGRSAIEDLLFNKVvtsglgtvdedykkcsagtdiADLVCAQYYNGVMVLPGVVDDNKMAMYTASLIGGMAMGSITSA----VAIPFAMQ VQARLNYVALQTDVLQENQKILANAFNNAMGNItlalgqvsdaistvSEGFNTMASALTKIQSVVNQQGNALSQLTQQLQNNFQAISSSIAEIYNRLEKV EADAQVDRLITGRLAALNAYVAQTLTQYTEVKASRQLAMEKVNECVKSQSDRYGFCGNGTHLFSLANAAPDGLLFLHTVLLPTEWEEVTAWSGICVNDtY AYVLKDfkSSIFSYSGTYMITPRNMFQPRKPQMSDFVQITSCEV-------------------- >UniRef50_A8JP00(180-1000:1128) Spike glycoprotein n=3 Tax=Rhinolophus bat coronavirus HKU2 RepID=A8JP00_9ALPC E=0 s/c=0.84 id=30% cov=67% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------------------------------DQSGAVTRYSYCADGFVNGLQCKLRLFDIPPGVY--SNSEVEYPVALYTVVHNMSVCP qrPESYCGSNYCP----FKRVVFSNCVVNYTSWTSGLLRD---------------------YQHLVLPNGKFNPFTECNG-----LNRIVDDCVTGFVLR VGRGT----------AVNRTVITPYLKPNE----------------------CF------------GWSWNDYQDSIYDWWIadfVSTGAFVCEKNPDAP -RTGVCITYTIEKVTFQGVLYESNFTFAQYYNVLY-FGSQLKYVR--ILGKVYEVAPCFEASYDVLF---RSSSSFGLLYRSFDCNQLrisasrfaerll pSHNGTATALGCLFNATYAPNDtmVNCTNPLGDGFCADLLSNVVVRRMTFEKHDTTYVAPVTIErfTELPLDHQLVLTEQFLQTTMPKFSISCETYICDV SKACKNLLFRYGGFCQKIEADIRGAGVLLDSDVSGLYSTIAAKTSSimPTTDRFnvSQFFLPKVQSTSERFESRSVIEDLLFSKiettgpgfygdyynck knaIQDLTCAQYHNGILVIPPVMDAETLGMY-GGIAAASLTLGI--FGGQAGITTWSLAMAGRLNALGVVQNALVDDVNKLANGFNQLTASVSKLALTTS SALQAIQAVVNQNAAQVESLVSGITENFGAISTNFKVISQRLDKLEADVQMDRLINGRMNVLQLFVTNYKLKIAELRNTHRYVQSLINECVYAQSLRNGF CGQGLHVLSLMQNAPSGIMFFHYSLIPNNTIIVKTTPGLCESDelgsKCIVAKDGVLVSANLSyWQWSPRNLYKPENLTFANVIAVS------------- ----------- >UniRef50_A3EXG6(34-1154:1274) Spike protein S2 n=4 Tax=Rousettus bat coronavirus HKU9 RepID=SPIKE_BCHK9 E=0 s/c=0.82 id=34% cov=94% ----------------------VLLPDPYIAYSGQTLRQNLFMADMSNTILYPVTPPAnganggfiYNTSIIPVSAGLFVNTwmYRQPASSRaycqepfG VAFGDTFENDRIAILIMapdnlgswsavapRNQTNIYLLVCsNATLCINPGF----NRWGPAGSFIAPDALVDHSNSCF--VNNTFSVNISTSRISLAFL FKDGDLLIYHSGWLPTsNFEHGFSRGSHPMTYFMSLPVGGNLPraQFFQSIVRSNAidkgdgmctNFDVNLHVAHLINRDLLVSYFNNGSVANAADCADS AAEELYCVTGSFDPPTGVYPLSRYRAQ-VAGFVRVTQRGSYCtPPYSVLQDP--PQPVVWRRYMLYDCVFDFTVVVDSLPTHQLQCYGVSPRRLASMCYG SVTLDVMRINETHLNNLFNRVPDTFSLYNYALPDNFYGCLHAFYLNSTAPYAVAN-----RFPIKPGGRQSNSAFiDTVINAAHYSP------FSYVYGL AVITLKPAAG------------------SKLVCPVANDTVVITDRCVQYNLYGYTGTGVLSKNTSLVIPDGkVFTASSTGTIIGV--SINSTTYSIMPCV TVPVSVGYHPNF---ERALLFNGLSCSQrsravtepvsvlwsasaTAQDAFDTPSGCVVNVELRNTTIvnTCAMPIGNSLCfINGSIATANADSLPRLQL VNYDPLYDNStatpmtpvywVKVPTNFTLSATEEYIQTTAPKITIDCARYLCGDSSRCLNVLLHYGTFCNDINKALSRVSTILDSALLSLVKELSINTRD evTTFSFDGDYNFTGLMgclgPNCGATTYRSAFSDLLYDKVritdpgfmqsyqkcidsqwggsiRDLLCTQTYNGIAVLPPIVSPAMQALYTSLLVGAVA SSGYTFGITSAGVIPFATQLQFRLNGIGVTTQVLVENQKLIASSFNNALVNIQKGFTETSIALSKMQDVINQHAAQLHTLVVQLGNSFGAISSSINEIFS RLEGLAANAEVDRLINGRMMVLNTYVTQLLIQASEAKAQNALAAQKISECVKAQSLRNDFCGNGTHVLSIPQLAPNGVLFIHYAYTPTEYAFVQTSAGLC HNGTGYAPRQGMFVlpNNTNMWHFTTMQFYNPVNISASNTQVLTSCSVNYTSVNYTVLEPsvpgdydFQKEFDKF >UniRef50_Q91AV1(201-1242:1383) Spike glycoprotein n=50 Tax=Alphacoronavirus RepID=SPIKE_PEDV7 E=0 s/c=0.77 id=27% cov=88% ----------------------VYTPTYYMLNVTSAGEDGIYYEPCTaNCTGYAANVFATDsNGHIPegFSFNNWFLLSNDSTLLHGKVV-SNQPLLVNC LLAIPKIYGLgqffsfnhtMDGVCNGAAVDRAPEALRFNINDTSvilaeGSIVLHTALGTNLSFVCSNSSDPHL----AIFAIPLGATEVPYYCFLkvdT YNSTVYKFLAVLPPTVREIVITKYGDVYVNGFGYLHLGLLDavTINFTghgtdddvSGFWtIASTNFVDALIEV-QGTSIQRILYCD-DPVSQLKCSQVA FDLDDGFYPISSrnlLSHEQPISFVTLPSFNDH----------------------------SFVNITVSAAFGGLSSANLVASDTTINGFSSFCVDTRQF TITLFYNVTN-------SYGYVSKSQDSNCPFTLQSVNDYLSFSKFCVS-----------------TSLLAGACTIDLFGYPAFGSGVKLTSLYFQFTKG ------------ELITGTPKPLEGITDVSFMTLDVCTKYTIYGFKGEGIITLTNSSILA-GVYYTSDSGQLLAFKNVTSGAVYSVTPCSFSEQAAYVNDD IVGV----------ISSLSNSTFNNTRELPGFFYHSNDGSNCTEPVlvysNIGVC----KSGSIGYVPSQYGQVKIAPTVTGNISIPTNFSMSIRTEYLQ LYNTPVSVDCATYVCNGNSRCKQLLTQYTAACKTIESALQLSARLESVEVNSMLTISEEALQLATISSFngDGYNFTNVLGasvyDPASGRvvqKRSVIE DLLFNKvvtnglgtvdedykrcsngrsVADLVCAQYYSGVMVLPGVVDAEKLHMYSASLIGGMALGGITAAAA----LPFSYAVQARLNYLALQTDVLQR NQQLLAESFNSAIGNITsafesvkeaisqtsKGLNTVAHALTKVQEVVNSQGSALNQLTVQLQHNFQAISSSIDDIYSRLDILSADVQVDRLITGRLSAL NAFVAQTLTKYTEVQASRKLAQQKVNECVKSQSQRYGFCgGDGEHIFSLVQAAPQGLLFLHTVLVPGDFVNVLAIAGLCVNGEiALTLREPGLVLFThel qtytaTEYFVSSRRMFEPRKPTVSDFVQIESCVV-------------------- >UniRef50_P05135(208-1020:1163) Spike protein S2 n=1237 Tax=Avian coronavirus RepID=SPIKE_IBV6 E=0 s/c=0.93 id=28% cov=72% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------LAYFVNGTAQDVILCDGSPTGLLACQYNTGNFSDGFYPFTNSSLVKEKFIV---------Y RESSVNTTLELTNFTFSNV--SNATPNTGGV------QTIQLYQTITAQSGYYNLNFSFLSSFIYKASD----------------YMYGSYHPSCKFRLE TINNGLWFNSLSVSLGYGPIQGGCKQSVfANRATCCYAYSYNGPSL-----CKGVYRGELTKSFECGLLVFVTKTDGSRIQTRNEPFTLTQHNYNNITLD RCVEYNIYGRVGQGFITNVTNYAINYNYLadggmaILDTSGAIDIFvvQGEYGLNYYKVNPCEDVNQQfvvsggklvgILTSRNETGSQPLENQFYIKII NGTRRSRRSITGNVTNCPYVTYGKFCIKPDGS---ISTIVPKELEHFVAPL------LNVTENVLIPDSFNLTVTDEYIQTRMDKVQINCLQYVCGNSLE CRKLFQQYGPVCDNILSVVNSVGQKEDMELLYFYSSTKpSGFNTPVLSNVstGEFNISLLLTPPSSASGRSFIEDLLFTSVesvglptddaykkctagpl gflKDLACAREYNGLLVLPPIITAEMQTLYTSSLVASMAFGGITSAGA----IPFATQLQARINHLGITQSLLFKNQEKIAASFNKAIGHMQEGFRSTSL ALQQIQDVVNKQSSILTETMASLNKNFGAISSVLQDIYQQLDSIQADAQVDRIITGRLSSLSVLASAKQAEYYRVSQQRELATQKINECVKSQSIRYSFC GNGRHVLTIPQNAPNGIVFIHFTYTPESFVNVTAIVGFCVNpanasQYAIVPANgrGIFIQVNGSYYITARDMYMPRDITAGDIVTLTSCQANYVSVNKT V----------- >UniRef50_B3FHU5(171-1058:1226) Spike n=17 Tax=Coronavirinae RepID=B3FHU5_CVTKE E=0 s/c=0.77 id=30% cov=71% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ----------------------------------------------------------INKLRCAYQQFNFSTGFYDIDTFVPVTSNITYlPYPDLKDnt gqeVCDFYVALKGDHV--------------IYNQSCVDSKYPFFKLKCNNTYSWDNDKLC---ILGSEIYVPGYNVY------TNTQHSYAGTIPNYPTC SSKGLSLENIYNNIGFNRFCVTKLLTT-------RDISSI------------TQYTCVYVVSVEGFDsYNQGIVYSY----VGVNFDFGTAMYSVKTAPM QFIYTEQCHKYNIYNIRGVGQILNVtgkdNTTLVDGGLVITSGSG-LLAFRN--NGSLFSVQPCRTVStQAVIVNGSFVGLFVPASCWLADQFNLGNHTE YVDGGCLISNKTISRKRRSTNAVYTGECTGLFAAMGtscIYSNGTVLNRTLPQPSVQtsvqpllgvvANVSIPKELTLAVTTEYLQTRYQKVTIDCAKYV CGDSTRCRTLLQQYGSFCQSVNAILSGVNENEDNGLLQYAEAINTGYTLNftgyNVSNLGGFDLSLVLPKNltlAQNQGRSTIEDLLFDKVvtlgvsevd qnydkciasrggsftnlADLTCAQFYNGVMVLPGVVDPGLMAVYTGSLIGGMALGGITAAA----SIPFATQIQARVNYLALTQSVLLDNQNLIANSFNK ALKGIQSALDTVSQgfvevargfesvtvALNKVQDVVNTHSDILNKLMAQLSVNFGAVSSSLNEIYLKLDQINADAQVDRLITGRLTALSTYVASLQLAA YKADQSRRLALQKVEECVKSQSMRYGFCGNGSHVLTIPQSAPNGIFFIHYTYQPTSYVTIEAVPGLCVTtpsgKYGVMPKtgSGIIFRQNDTFFVTSTQL YEPKLLSYSEVVNLTSCEANYYNVSES-ETPFQPALPNF # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * Q 1 * * * * * * * * * * * * * 0 * * * * * * 1 0 * * * * * * 1000 0 0 C 2 * 0 * * * * * * * * * * * * * * * * * * 2 0 * * * * * * 1000 0 0 V 3 * * * * * * * * * * * * * * * * * 0 * * 3 0 * * * * * * 1000 0 0 N 4 * * * * * * * * * * * 0 * * * * * * * * 4 0 * * * * * * 1000 0 0 L 5 * * * * * * * * * 0 * * * * * * * * * * 5 0 * * * * * * 1000 0 0 T 6 * * * * * * * * * * * * * * * * 0 * * * 6 0 * * * * * * 1000 0 0 T 7 * * * * * * * * * * * * * * * * 0 * * * 7 0 * * * * * * 1000 0 0 R 8 * * * * * * * * * * * * * * 0 * * * * * 8 0 * * * * * * 1000 0 0 T 9 * * * * * * * * * * * * * * * * 0 * * * 9 0 * * * * * * 1000 0 0 Q 10 * * * * * * * * * * * * * 0 * * * * * * 10 0 * * * * * * 1000 0 0 L 11 * * * * * * * * * 0 * * * * * * * * * * 11 0 * * * * * * 1000 0 0 P 12 * * * * * * * * * * * * 0 * * * * * * * 12 0 * * * * * * 1000 0 0 P 13 * * * * * * * * * * * * 0 * * * * * * * 13 0 * * * * * * 1173 0 0 A 14 993 * * * * * * * * * * 1007 * * * * * * * * 14 0 * * * * * * 1173 0 0 Y 15 * * * * * * * * * * * * * * * * * * * 0 15 0 * * * * * * 1735 0 0 T 16 * * * * * * * * * * * * * * * * 715 1356 * * 16 0 * * * * * * 1735 0 0 N 17 * * * * * * * * * * * 1701 * 530 * * * * * * 17 518 1729 * 1000 1000 * * 1735 1000 0 S 18 * * * * 1356 * * * * * * * * * * 715 * * * * 18 0 * * * * * * 1735 0 0 F 19 * * * * 1701 * * * * * * * * * * 1729 * 1356 * * 19 0 * * * * * * 1735 0 0 T 20 * * * * * * * * * * 1729 1356 * * * * 1701 * * * 20 0 * * * * * * 1735 0 0 R 21 * * * * * * * * 1356 * * * * * 715 * * * * * 21 0 * * * * * * 1735 0 0 G 22 * * * * * 715 * * * * * * * * * * 1356 * * * 22 0 * * * * * * 1735 0 0 V 23 * * * * * * * * * * * * * * * * 2275 334 * * 23 0 * * * * * * 2395 0 0 Y 24 * * * * * * * * * 2608 * * * * * * * * * 259 24 0 * * * * * * 2816 0 0 Y 25 * * * * * * * * * 2608 * * * * * * 2705 * * 551 25 243 * 2690 * * * * 2816 0 0 P 26 * * * * * * * * * * * * 0 * * * * * * * 26 545 1668 * 1000 1000 * 0 2606 1307 1000 D 27 * * 1050 * * 1668 * * * * * * * * * * 2305 * * * 27 0 * * * * * 0 2606 0 1000 K 28 2654 * * 2759 * * * * 2784 * * * 2395 * * 2683 * * * 2305 28 0 * * * * 0 * 2606 0 1000 V 29 * * * * * * * 2973 * * * 2883 * * * * 1769 2985 * 1656 29 0 * * * * * * 2816 0 0 F 30 * * * * 1351 * * 2608 * * 2705 * * * * * * * * 1784 30 0 * * * * * * 2816 0 0 R 31 2608 * * * * * * * * 2705 * 2690 * * 922 * * * * * 31 0 * * * * * * 2816 0 0 S 32 * * * * * * * * * * * 780 * * * 1979 * * * 2608 32 0 * * * * * * 2816 0 0 S 33 * * 2973 * * * * * * 2883 2853 * * * * 1784 2690 2705 * * 33 0 * * * * * * 2816 0 0 V 34 1868 * * * * 1648 * * * * * * * * * * 1833 2985 * * 34 0 * * * * * * 2816 0 0 L 35 * * * * * 2690 * * * 922 * * * 2608 * 2705 * * * * 35 0 * * * * * * 2816 0 0 H 36 2705 * * * * * 2985 * 2853 * * * * * * * 1138 * * 2973 36 0 * * * * * * 2816 0 0 S 37 * * * * * 780 * * * 1779 * * * * * 2985 * * * * 37 0 * * * * * * 2816 0 0 T 38 * * * 2705 * * * * * * * * * * 2608 * 922 2690 * * 38 0 * * * * * * 2816 0 0 Q 39 * * 2705 * * * * * * * * 1784 * 1259 2853 * * * * * 39 0 * * * * * * 2816 0 0 D 40 * * 1979 * * 2705 * * * 2853 * 2608 * 2690 * * 2883 * * * 40 0 * * * * * * 2816 0 0 L 41 * * * * * * * 2705 * 240 * * * * * * * * * * 41 215 * 2853 * * * * 2816 0 0 F 42 * * * * 1077 * * * * * * * * 2540 * 2443 * * * 2556 42 0 * * * * * 0 2678 0 1000 L 43 * * * * * * * * * 631 2440 * * * * * * * * 2556 43 293 * 2443 * * * 0 2678 0 1000 P 44 2128 * * 2297 * 2275 * * * * * * 1469 * * * * * * * 44 0 * * * * * 0 2395 0 1307 F 45 * * 2128 * 1469 * * * * 2275 * * 2297 * * * * * * * 45 0 * * * * * 0 2395 0 1307 F 46 * 1286 * * 2462 * * * * * 2128 * * * * * * * * 2476 46 0 * * * * * 0 2395 0 1307 S 47 * * * 2275 * * * * * * * * * * * 761 2297 * * * 47 328 2297 * 0 * 991 1009 2395 1000 1307 N 48 * * 2543 * * * * * * * * 638 * * * 2426 * * * * 48 272 2543 * 1000 1000 * 0 2693 1000 1000 V 49 * 1553 * * * * * * * * * * * * * * 1432 1793 * * 49 0 * * * * 0 * 2693 0 1000 T 50 2690 * * * * * * 2608 * 2853 * * * * * * 882 * * * 50 0 * * * * * * 2816 0 0 W 51 * * * * * 1199 * * * 2608 * * * * * * * * 1321 * 51 0 * * * * * * 2816 0 0 F 52 * * * * 922 * * * * * * * * * * * * * * 1082 52 0 * * * * * * 2816 0 0 H 53 2705 * * * * * 1979 * 1868 * * * 2608 * * * * 2690 * * 53 0 * * * * * * 2816 0 0 A 54 1838 * * * * * * * * * * * 1868 * * * 1825 2608 * * 54 462 * 1868 * * * * 2816 0 0 I 55 * * * * * * * 1469 * * * 1286 * * * * 2128 * * * 55 0 * * * * * 0 2395 0 1307 H 56 * * * * * * 2462 * * * * 2476 2128 * * * * 1286 * * 56 0 * * * * * 0 2395 0 1307 K 57 * * * * 1286 * 2476 * 2462 * * * 2128 * * * * * * * 57 0 * * * * * 0 2395 0 1307 R 58 1210 * * * * * * * * * * * * * 2462 * 1372 * * * 58 375 2128 * 3000 193 * 0 2395 1000 1307 F 59 * * * * 1469 * * * * * * * 2275 * * * 2297 * * 2128 59 0 * * * * * 0 2395 0 1307 D 60 * * 1377 * * 2476 * * * * * 2128 * * * * * 2275 * * 60 328 2297 * 0 * * 0 2395 1000 1307 N 61 * * * * * * * * * * * 375 * * * * 2128 * * * 61 0 * * * * 0 * 2395 0 1307 P 62 * * * * * 1698 * * * * * * 922 * * 2608 * * * * 62 0 * * * * * * 2816 0 0 V 63 * * * * 1868 * 2705 2608 2690 * * * * * * * * 1979 * * 63 0 * * * * * * 2816 0 0 L 64 * * * * * * * 738 * 1321 * * * * * * * * * * 64 462 1868 * 0 * * * 2816 1307 0 P 65 * * * 2883 * * * * * * * * 210 * * * * * * * 65 532 1698 * 1000 1000 * * 2816 1415 0 F 66 * * * * 228 * * * * * * * * * * * * 2774 * * 66 0 * * * * * * 2948 0 0 N 67 * * * * * * * * 3123 * * 1037 * * * 1329 * * * * 67 0 * * * * * * 2948 0 0 D 68 2774 * 1068 * 1408 * * * * * * * * * * * * * * * 68 0 * * * * * * 2948 0 0 G 69 * * * * * 682 * * * * * 1990 * * * 2999 * * * * 69 0 * * * * * * 2948 0 0 V 70 * * * * * * * 1456 * 2774 * 1408 * * * * * 3153 * * 70 194 * 2988 * * * * 2948 0 0 Y 71 * * * * 1757 * * * * * * * * * * * * * 1076 2121 71 0 * * * * 0 * 2988 0 1000 F 72 3153 * * * 406 * * * * * * * * * * * * 2911 * * 72 172 3153 * 3585 126 * * 3110 1000 0 A 73 1209 * * * * * * * * 1654 3100 2911 * * * * * * * * 73 0 * * * * * * 3110 0 0 S 74 3264 * * * * * * * 3127 1654 * * * * 3100 3298 2027 * * * 74 206 2911 * 1000 1000 * * 3110 1000 0 T 75 * * * * * * * * * * * * * * * 1625 1223 3127 * 2911 75 0 * * * * * * 3110 0 0 E 76 * * 3219 2281 * * * * 3127 * * 1613 * * 2911 * * * * 3153 76 0 * * * * * * 3110 0 0 K 77 * * 3261 * 3153 * * * 1675 * * 3127 * 2911 * 2167 * * * * 77 0 * * * * * * 3110 0 0 S 78 * * * * * * * * * * * * 2027 * * 406 * * * * 78 0 * * * * * * 3110 0 0 N 79 2911 * * * * * * * * * * 2281 * * 3127 * 871 * * * 79 0 * * * * * * 3110 0 0 I 80 * * * * 2113 * * 1226 * 3261 * * * * * 2911 * 3264 * * 80 0 * * * * * * 3110 0 0 I 81 * * * * * * * 3298 * 3261 * * * * * 2015 * 871 * * 81 0 * * * * * * 3110 0 0 R 82 * * 3237 * * * 3261 3153 3127 * * * * 3219 1562 3100 * * * * 82 206 2911 * 2807 222 * * 3110 1000 0 G 83 * * 3127 * * 175 * * * * * * * * * * * * * * 83 0 * * * * * * 3110 0 0 W 84 * * * * * 3127 * * 3261 * * * * * 1599 3153 * 2911 2281 * 84 179 * 3100 * * * * 3110 0 0 I 85 2774 * * * * * * 2074 * 3016 * * * * * * * 1021 * * 85 0 * * * * 0 * 2948 0 1000 F 86 * * * * 817 * * 3127 * * * * * * * * * 1654 * * 86 552 * 1654 * * * * 3110 0 0 G 87 * * * * * 673 * * * * * * * * * * * 2228 * 2651 87 0 * * * * 0 * 2658 0 1636 T 88 * * 2911 * * * * * * * * 3153 * * * 899 2196 * * * 88 0 * * * * * * 3110 0 0 T 89 * * * 2181 * * * * * * * 2178 * * * 3219 1149 * * * 89 172 * 3153 * * * * 3110 0 0 L 90 * * * * 1746 * * * * 3140 3115 * * 1080 * * * * * * 90 0 * * * * * 0 3000 0 1000 D 91 * * 3140 2759 * * * * * * * 3115 682 * * * * * * * 91 0 * * * * 0 * 3000 0 1000 S 92 3127 * * * * * * * * 2178 * 2077 * * * 2224 * 2228 * * 92 0 * * * * * * 3110 0 0 K 93 * * 2911 * * * * 3127 2281 1613 * * * * * * * * * 2185 93 0 * * * * * * 3110 0 0 T 94 * * * * * * * * * 3237 * * * * 2911 3264 1606 1606 * * 94 0 * * * * * * 3110 0 0 Q 95 * * * 3219 * * * 2015 * * 3237 2178 * 2281 * * * 3153 * * 95 0 * * * * * * 3110 0 0 S 96 2911 1203 * * * 3127 * * * * * * * * * 2281 * 3153 * * 96 0 * * * * * * 3110 0 0 L 97 * * * * * * * 2911 * 625 * * * * * 3127 * 3264 * * 97 0 * * * * * * 3110 0 0 L 98 * * * 3153 * * * 3264 * 1561 * * * * 3219 * 3127 * 2167 * 98 0 * * * * * * 3110 0 0 I 99 2249 * * * 3127 * * 1562 * * * * 1571 * * * * * * * 99 0 * * * * * * 3110 0 0 V 100 * * * * * * * 2262 * * 2911 * * * * * * 872 * 3153 100 206 2911 * 3700 115 * * 3110 1000 0 N 101 * * * * * * * * * * * 1209 1203 * 2911 * * * * * 101 0 * * * * * * 3110 0 0 N 102 * * * * * 3237 * * 3261 * * 1149 * * * 2158 3127 * * * 102 162 3237 * 1000 1000 * * 3110 1000 0 A 103 3298 * * * 3100 * * 2206 * * * * * 2911 * 1623 * * 3219 * 103 172 * 3153 * * * * 3110 0 0 T 104 * * * * * 2988 * * * * * * * * * 3088 1023 * * 1920 104 0 * * * * * 0 3000 0 1000 N 105 * * * * * 3135 * * * * * 714 * * * 2734 * 2988 * * 105 181 3088 * 1000 1000 0 * 3000 1000 1000 V 106 2158 * * * * * * 1475 * 3261 * * * * * 3237 * 2281 * * 106 159 3261 * 3170 170 * * 3110 1000 0 V 107 3100 * * * 3237 * * 3219 * * 2206 * * * * * * 1643 * 2911 107 175 3127 * 4087 87 * * 3110 1000 0 I 108 3153 * 3261 * * * * 1643 * 2911 * * * 3100 * * * 2228 * * 108 0 * * * * * * 3110 0 0 K 109 * * * * * 3261 * * 3298 2911 * * * 3100 3264 1581 * * * 3237 109 0 * * * * * * 3110 0 0 V 110 3264 * * * 1599 * * * * * * * * * * * * 822 * * 110 162 3237 * 3000 193 * * 3110 1000 0 C 111 * 164 3219 * * * * * * * * * * * * * * * * * 111 414 2002 * 1196 828 * * 3110 1589 0 E 112 * * * 3298 * * * * * * * 850 * 2113 * * 3153 * * * 112 0 * * * * * * 3110 0 0 F 113 2911 * 3219 * 1633 2249 * * * * * * * * * * * * * 2140 113 0 * * * * * * 3110 0 0 Q 114 3261 * * 3264 * * * * * * * * * 3298 * 3100 1098 * * 3237 114 0 * * * * * * 3110 0 0 F 115 2249 * * * 2258 * * 3153 * 2077 3127 * * 3100 * * * * * * 115 0 * * * * * * 3110 0 0 C 116 * 341 * * * * * * * * * * * * * * 3237 3261 * * 116 366 2158 * 2918 205 * * 3110 1387 0 N 117 * * 1669 3127 * * * 2911 * * * 1618 * 3153 * * * * * * 117 0 * * * * * * 3110 0 0 D 118 * * 3298 * * * * * * 2185 * 1500 * * 3261 3237 * * * 3127 118 0 * * * * * * 3110 0 0 P 119 2249 * * * * * * * * * * 3219 822 * * * 3100 * * * 119 0 * * * * * * 3110 0 0 F 120 * * * * 1254 2911 3127 * * * * * 3261 * * * * 3100 * 3153 120 175 * 3127 * * * * 3110 0 0 L 121 * * 2983 2117 1928 * * * * 3135 * * * * * 3092 2747 * * * 121 229 * 2768 * * * 0 2988 0 1000 G 122 1307 * * * * 1879 * * * * * * 2475 * * * * 2795 * * 122 0 * * * * 994 1006 2749 0 1550 V 123 * 2923 * 3015 * * * 2931 * 2061 * * * * * * 2917 2052 * * 123 188 * 3032 * * * 0 2888 0 1000 Y 124 * * * * * * * 2776 2783 * * * * * 1325 * * 2892 * 2515 124 0 * * * * * 0 2815 0 1556 Y 125 * 2776 * * 905 * * * * * * * 2783 * * * * * * 2515 125 0 * * * * 1054 948 2815 0 1556 H 126 * * * * * * 1377 * * * * 994 * * * 3147 * * * * 126 0 * * * * * 0 3052 0 1000 K 127 * * * * * * * 3163 2788 2081 * * 2058 * 2787 * 3033 * * * 127 0 * * * * 0 * 3052 0 1000 N 128 * * * * * * * * * * * 390 * * * 3264 * * 2911 * 128 162 * 3237 * * * * 3110 0 0 N 129 3008 * 3018 * 2894 1901 * * 3142 2999 * 3164 * * * * * * * * 129 0 * * * * * 0 3001 0 1000 K 130 * * * * * 2999 * * 3164 * * 3028 1952 * * * 1387 * * * 130 0 * * * * * 0 3001 0 1000 S 131 1308 * * * * * * * * * 3142 2999 * * 3028 2089 * * * * 131 408 2023 * 2322 322 0 * 3001 1575 1000 W 132 * * 3219 * 3237 1551 3153 * * 3100 * * * 3127 * * * * 3298 * 132 0 * * * * * * 3110 0 0 M 133 * * 3219 * * * * * * * 3298 * * * 3127 2075 1632 3100 * * 133 0 * * * * * * 3110 0 0 E 134 * * 2195 3298 2911 * * 2192 * * * * * 1608 * * * * * * 134 0 * * * * * * 3110 0 0 S 135 * * * 2181 * * * 2057 * * * * * * * 2196 3264 2206 * * 135 0 * * * * * * 3110 0 0 E 136 2911 * * 3298 * 3100 3264 3219 3153 2192 * * * * 3237 * * * * * 136 0 * * * * * * 3110 0 0 F 137 * * * * 1760 * 3396 * * * 3256 * 2203 * * * 3459 3376 3311 * 137 0 * * * * * * 3285 0 0 R 138 * * 3082 * 3376 3256 3311 * 3195 * 3459 * 3335 * 3493 * 2380 * * * 138 0 * * * * * * 3285 0 0 V 139 1272 * * * 3364 * * 2396 * * * * * * * * * 2336 * 3311 139 0 * * * * * * 3285 0 0 Y 140 * 3335 3311 3364 3459 3376 * * * 2231 * * * * * * 3256 * * 2336 140 0 * * * * * * 3285 0 0 S 141 * * 2411 * 3195 3396 * * * 3335 * * * * * 2433 3311 2167 * * 141 0 * * * * * * 3285 0 0 S 142 * * 1608 * 3256 3376 * * * 3335 * 2411 * * * 3493 3396 * * * 142 0 * * * * * * 3285 0 0 A 143 2476 * * * * * 3082 * 3335 3195 * 3396 * * * 1746 * 3311 * * 143 0 * * * * * * 3285 0 0 N 144 * * * * 3459 * * 3195 * 2325 * 3493 * * 3335 3082 3364 2343 * * 144 0 * * * * * * 3285 0 0 N 145 3364 * * * * * * * * * * 711 * * * 2353 * 3376 * * 145 147 3364 * 1000 1000 * * 3285 1000 0 C 146 * 1359 * * 2366 * * * * 3376 * * * * * 2216 3256 * * * 146 0 * * * * * * 3285 0 0 T 147 * 2216 * * * * * * * 2343 * * * * * * 1021 3396 * * 147 160 3256 * 2585 263 * * 3285 1000 0 F 148 * 3396 * * 982 * * 3256 * * * * * * * * * 3376 * 2338 148 181 * 3082 * * * * 3285 0 0 E 149 * * * 2296 * * * * * * * 2177 * * 2023 1603 * * * * 149 365 * 2163 * * * 0 3064 0 1000 Y 150 * 2809 * * * 1865 * * * * * 2920 * * * * * * * 1150 150 288 * 2468 * * 535 1691 2720 0 1777 V 151 3092 * * * * * * 3107 * 3105 * * * * * 3130 * 1288 * 2983 151 0 * * * * 987 1013 2988 0 1544 S 152 * * * * * * * * * * * 738 * 3268 * 1753 * * * * 152 0 * * * * 0 * 3165 0 1000 Q 153 3335 * 1783 * * * * * * * * 3082 * 3493 3311 * * 3364 * 2282 153 0 * * * * * * 3285 0 0 P 154 3459 * * * * * * * 3376 * * 3311 1822 * * * 1221 * * * 154 147 3364 * 0 * * * 3285 1000 0 F 155 * * * * 1015 * 3396 3195 * * * * 3364 * * * * 3256 3335 * 155 0 * * * * * * 3285 0 0 L 156 * * * * * * * * * 1822 * * * * * 1286 1703 * * * 156 144 * 3397 * * * * 3285 0 0 M 157 * 3156 * 2023 * * * 3169 * 3359 3398 * * * * * * 2986 * 2237 157 161 * 3242 * * * 0 3150 0 1000 D 158 * * 1025 * * 3051 * * * * * 2850 * * * 2962 3046 * * * 158 0 * * * * * 0 3060 0 1574 L 159 * * * 2839 3051 * * 2850 * 3246 * 3046 * * * 2962 * 2022 * * 159 164 3220 * 2322 322 * 0 3060 1000 1574 N 160 * * * * 2962 * * * * * * 448 * * * 2850 * * * * 160 0 * * * * 1066 937 3060 0 1574 F 161 1481 * * * 2359 * * * * * * * * * * 3274 2108 * * 3165 161 0 * * * * * 0 3170 0 1000 K 162 * * 2973 2103 * * * 3301 2359 * * * * * * 2064 3260 * * * 162 0 * * * * * 0 3170 0 1000 N 163 3274 * * * 3301 * 3339 * * * * 3380 * * 2970 3260 * * 2949 2066 163 398 3165 2949 0 * * 0 3170 1000 1000 L 164 3135 * * 2988 * * * 2759 * 1399 * * * 3088 * * * 3113 * * 164 177 3113 * 2000 415 * 0 3000 1000 1546 R 165 * * * * * * * 1080 * * * * * * 2128 2759 * * * 2734 165 235 * 2734 * * * 0 3000 0 1546 E 166 * * * 1868 * * * * * 2494 * * 1310 * * 2785 * * * * 166 0 * * * * 0 * 2742 0 1755 F 167 3082 * * * 346 * * * * 3396 * * * * * * * * * * 167 0 * * * * * * 3285 0 0 V 168 * * * * 3082 993 2323 * * * * * * * * * * 2476 * * 168 0 * * * * * * 3285 0 0 F 169 3396 * * * 1397 3364 * 3195 * 3082 * 3376 * * * * * 3256 * * 169 0 * * * * * * 3285 0 0 K 170 * * * * 3082 * * * 2476 * * * * * * * 1301 3376 * 2323 170 0 * * * * * * 3285 0 0 N 171 3364 * 3256 3396 * * * * 3082 * * 2476 * 1694 * * * 3376 * * 171 0 * * * * * * 3285 0 0 I 172 * * 1624 2343 * 3256 * 3493 3459 * * * * 3335 * * * 3396 * * 172 0 * * * * * * 3285 0 0 D 173 * * 2476 * * 1653 * * * * * * 1347 * * * 3195 * * * 173 0 * * * * * * 3285 0 0 G 174 * * 3082 * 3376 1397 * * * * * * * 3195 3256 * * * * 2380 174 0 * * * * * * 3285 0 0 Y 175 * * * * 3459 3195 * * * 2216 * * * * * * 2323 * * 1378 175 0 * * * * * * 3285 0 0 F 176 * 1347 * * 1792 * * * * 2258 * * * * * * * 3195 * * 176 0 * * * * * * 3285 0 0 K 177 * * * * 1347 * 3195 3082 3493 * * * * * * * * * * 1782 177 0 * * * * * * 3285 0 0 I 178 1715 * * * * * * 3493 * 2292 * * * * * * * 1814 * 3082 178 144 3397 * 1585 585 * * 3285 1000 0 Y 179 * * * * * * 3082 * * 3256 * 3364 * * * 3376 3396 * * 1032 179 0 * * * * * * 3285 0 0 S 180 * * * * 2338 * * 3376 3459 * * * * * * 1661 * * * 1743 180 0 * * * * * * 3285 0 0 K 181 3335 * * * * 2258 * * 3493 * * 1757 * * * 2277 3311 * * * 181 0 * * * * * * 3285 0 0 H 182 * * 2323 * * 2315 3493 * * * 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* 3211 0 0 T 1049 * * * 3315 * * * * * 3084 * * * * * 3205 571 * * * 1049 166 * 3205 * * * * 3211 0 0 V 1050 * * * * * * * * * * 2900 * * 3153 * * 3201 633 * * 1050 0 * * * * 0 * 3050 0 1000 Y 1051 * * * 2869 * * * 2964 * 1316 * * * * * * * * * 1585 1051 0 * * * * * * 2953 0 0 D 1052 * * 1116 2850 * * * * * * * 2807 3056 * * * 2869 * * * 1052 0 * * * * * * 2953 0 0 P 1053 * * * 2854 * * * * * * * * 851 2772 * * 2635 * * * 1053 243 2690 * 2807 222 * * 2774 1000 0 L 1054 * * * * 1683 * * * * 1391 * * * * * 2635 * 2772 * * 1054 215 * 2854 * * * * 2774 0 0 Q 1055 * * * * * * * * * * * * * 294 * * 2439 * * * 1055 0 * * * * 0 * 2603 0 1000 P 1056 * * * * * * * * 2690 * * * 243 * * * * * * * 1056 0 * * * * * * 2774 0 0 E 1057 2676 * * 878 * * * * * * * 2635 * 2854 * * * * * * 1057 0 * * * * * * 2774 0 0 L 1058 * * * * 1730 * * * * 517 * * * * * * * * * * 1058 0 * * * * * * 2774 0 0 D 1059 * * 859 * * * * * * * * * 1156 * * * * * * * 1059 0 * * * * * * 2322 0 0 S 1060 * * 2155 * * * * * 2234 * 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