HHsearch 1.5 NAME c8ww7L_ FAM FILE c8ww7L_ COM /bmm/www/servers/phyre2/HH/hhmake -i c8ww7L_.a3m DATE Sat May 3 12:09:33 2025 LENG 884 match states, 884 columns in multiple alignment FILT 115 out of 117 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 4.5 EVD 0.3441 -7.0175 SEQ >ss_pred CEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEEHHCCCCCCCCCC CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHCCHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEECCCCCC CCCCHHHHHEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHCHHHCCCHHHHHHHHHHHHHCCCCC CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECC CCCCCEEEEEECCCCCCCCCCCCHHHHHHCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH CCCHHHHHHCCCCCEECCCCCEEEEECCCCCCCCCCHHHCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHEEEEEE CCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCEEEEEECCCCEEEEEEEEEEEEE CCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHH HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCC >ss_conf 9145102110167998999862366347626887688402333100013781788999999998741756324146777753279861000100266766 6315888989888876531000134321101232178714999617677721456530100017730577621386463111363346545112367678 8873010000013345432111210147776511588887641167821101110044413224503889986303442158788999999875235765 3210256776567624667788998647631257664233124455543085888998623411112000000222222114899998740680465315 7875014774135654435630001233075468888622024454343320243246541388999877654432479998610012357999999984 2804677614797562038827982258560147881010331037899986786568999999974227878899999999888735898241999995 3788728999999999730000233685785412466667786676417974999833676763386765443279816766227871898875689983 2887742778831563689850687367765556301221010012321011345655999999999999999852899888789999999999852538 887544521277654799999999985123222101467877322110101025777750589886787252002414699999 >Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxpxxkxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxgxxxxxxxxxxxxxxxxxdxdxkxxxxxxpxx xxxxxxxxxxxxxxxxxnxxxlxxxxxxxxxxxxxxxxgxhxxxxxxxxxxxxxkxxxxxxxxxxxxxxxixxxxxxxxxxxldxxsxkxpwxxygsskx xxxpyxxkxxxxxdxxsxxxxxxxxxxxxxxxxxxxxxxxxxxxexxxxxxxxxxxxxxxxxxxxxxxxxixxxLxxxxxxdxxxwxxvxxxlxntxxxx xxxxxwxxxxxxxKxxxxdexxcxxlWxxxxxxxxnxxTxxsLxyxAkkxnpxxYxxxxxxxxxxxxxxxxtxxxxxxthxxiAkixxxxxxxxfvxxxx sxxnxvWxxfxxxxxxxxxgxxxxxxexxxxxxlrxxisxxxxxvxxxxdxxxxxxxxxxxxxxixxexxkxxxxxxxxxxxxxnxxxkxgVlrxxxxlf xxxxfixxLDxdpxLLxxxNGvlDLrTxxgxLrxhxxedxiTxxtxvxYdpxaxxpxwxkfLxxixxxxxpDxxxrxxlqrxxgyxLxGxxxEqxxlilx GxGxNGKStlxxiixxiLGdyxasxxxxxxlxxxxxxxxxxxxdLArLxGxRlvxxsExxegxxlnexxIKxlTGGDxIxARxlxkxxfeFxPxfKlilx tNhxPxIxgxDxgiWRRlxiIPFxxxixxxxdxxxxxkxexDpxlxxdxxxxxkLxxExxgILxWlieGxxxxxxxGlklxxPxxVxxAtxeYrxesDxi xxFleExxixxxxxsxlYxaYkeWxxxNxxxxxxxxxkxxxxlxxxVxxkxxqxxxxxtrxxKGxrlxxxexxxxwxxxxpxxx >c8ww7L_ TIQLTAQRKYLAEVQALETLLTRELSVFLTEPGSKKTNIINRITGKTYALPSTELLRLYEHLEQCRKQGALMYFLERQGTYSGLMLDYDLKLNTNAVPPL EPPALSRLCHRIFVHIKNSSVLIHFFFTLKPEVVQGKYGFHVLIPGLKLAASTKKSIIGSLQHDATVQKILHEQGVTNPESCLDPHSASVPSLLYGSSKL NHKPYQLKTGFELVFDSSDPDYIPIHQIKNLESYNLVSELSLTNEQGSLVRPVSLSILMLHDPEARYLHKILNLLPPEYYVEYPLWSNVVFALANTSANY RPLAEWFSQKCPEKWNTGGKEKLEKLWNDASHHTEKKITKRSIMYWAHKHAPQQYKEIVEQGYFSILAEYVYSYNGMLEHYMIAKVIYAMMGNKFVVDVD SNGKYVWFEFVLPGQPMNQGEIWKWRKEVNPDELHIYISENFSRVMDRITEHIKYHLSQPHESNILNYYKKLLKAFERSKSKIFNDSFKKGVIRQAEFLF RQRSFIQTLDTNPHLLGVGNGVLSIETIPAKLINHFHEHPIHQYTHICYVPFNPENPWTKLLLNALQDIIPELDARLWIMFYLSTAIFRGLKEALMLLWL GGGCNGKTFLMRLVAMVLGDHYASKLNISLLTSCRETAEKPNSAFMRLKGRGYGYFEETNKSEVLNTSRLKEMVNPGDVTARELNQKQESFQMTATMVAA SNYNFIIDTTDHGTWRRLRHYRSKVKFCHNPDPSNPYEKKEDPRFIHEYIMDPDCQNAFFSILVYFWEKLQKEYNGQIKKVFCPTIESETEAYRKSQDTL HRFITERVVEVYNLSEVVTAYAEWYNTNINVKRHIALELSQELENSVLEKYLQWSPNKTRILKGCRILICEPKNKWWEWSPNPS >UniRef50_A6M3C4(220-562:615) ATPase-like protein n=1 Tax=Clostridium beijerinckii NCIMB 8052 RepID=A6M3C4_CLOB8 E=3e-14 s/c=0.24 id=20% cov=22% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------EGEEEKIISSAKFKKILSHADESARKTNEGLTNVSLQNLdIVF DTNAMPSFSTMDSAISRRLIFVKFDKPIPIEKRNADYYKDEIFPNFDYVFSYFV----------------YKAIDMIGKKLNIPDCVKNDTSTKLSEVDS LLSF-SKRIITPFEGS--YIKYSEFEEEYLNFCEEEGLE-------SVIPYSFQDTGNKKNQTKRCNYIINLLKEK--------- >UniRef50_Q9HSI4(237-824:857) Putative uncharacterized protein n=1 Tax=Halobacterium salinarum RepID=Q9HSI4_HALSA E=4e-39 s/c=0.28 id=16% cov=43% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -------------KWDNQAERNIQDIWDSASE--GQGVTVGTLIHYAKdggwtvptRSNPTGQSqenghtkplvEAIDSSWFDLDSKTVTVQSVEGYtas elvdvfqksgnileacgHEAISAIGESDGGGEFL---DDSGNG-WTVEEGRKNPYAHLEPLSNQEIKNTAlaelPTHRVAYLPKREIWLWCDDGVWKPNG DGWVRQWLDEYLGPYYSGHIRREVMDQLQARSQV--EEQRFGGGP---------PGQIAAQNGLIDLD-AGEIMREIQPSDHIRWTLATEYDPEADCRKW REFLGEVV-----EASDIPLLQEYIGYCLRHwDVKRKKALMLLGPTDAGKSVFVDVIEALFGGEDSAATSSTSVQYLANERWGP----ARLVNTALNTRS DLGKGSIENTGKVKELIAGDSLDAERKRKPVFQFKPTAKHIFAANRAPNRSVDDEAFWNR---------------------------------------- ---------------------------------------------------------------------------------------------------- --------------------------- >UniRef50_UPI00003C83E3(5-819:980) virulence-associated protein E n=1 Tax=Ferroplasma acidarmanus fer1 RepID=UPI00003C83E3 E=1e-153 s/c=0.67 id=16% cov=84% --------KYDAEIIAAAKKYTKAgLPIFPTKPGSKEPDTVHGFKDATND---------FNKFMQMHRPGDGIAMPTGASTY--IIIDPDVAKDENKKPI KKDGKVIRIGLDNLCKQFNLLGLEDSKLQTLVTETQSG-GDHFWFRNPKGKPPLKKMQGN--ENNGIDKVDIQAEGAY---VVLPPTEGKFGKYKFITDV PFDEipemPLEFYNFFAGTEKKSENDADLIEYGGEYHPSN----FKFDNEKTPLLISTIADITKRSNTgiGAEMTMYITGTLAFHNFEEPHA-LAVLKKV ANINGYEKTDWIPIVKDTYKKFGTKDKN-------------GNQHKIRGLPWLKKLLAEHKefwnnYDEIIK-NLEILFPENLYDIAERMLNlarVGPAK VVSIILETEHVVTKSDNTTDL-----EEIYLYHDGFYARGEEELKIESARIYTDawNKALELANKLAPKTDELSPDTTKAifEIRESMKKVIER-GPTRS QINETLAQ---LRLA--TYTNPD---KFNPDSH-IPFLNGY--LNTKTWKLEPHNPDliYLWRIEANLNADKLDvvrlqDSPKFSKFINETFEDRD---- -IPLILQYFGYTMYPDFPRQMVLFMTGRERVGKGSLVRILKKMNPYGYGSISFEKLIMNDN------RFAFQGIEGKNLLVDTEImryhRRGQTIDYRNI NKLFGGDVIDLEKKGVTPTDYISKAKGIFLGN-LPLPKVTDEPFLARVILV-----------KTKDHKIEQGERIAN--IEDVILSEERDTIATLLVHHL MELSANNWNFTNEMTTDETVELWNLLSDIVEFYTDDEIDDVPEMeipvNTVYDSFKRW------------------------------------------ ------------------ >UniRef50_D2XAF6(41-893:903) D5 family helicase-primase n=1 Tax=Marseillevirus RepID=D2XAF6_9VIRU E=1e-159 s/c=0.66 id=23% cov=70% ---------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------EKCIDSLKGK-PWLMYGSTKP GNlgdflEPYTISQVYsdeleEIDVDSllgEEADEMDLEIPKDLpyilsiqrrrEPTPIVrgiipSEKKMTRRKRPARLTKTVDQIMADIAEVRN-SRVL DMLDSSRAENYDDWMNVGWTLFNI-GNGLPEALELWIDFSSRASNFDEKKCEYLW-DTMEMKGKSI--GSLYQMAKNDNPEKYNDWKKEKSSEAMKGAMT AAKP--THANIASLIHIKYSDRFVC-ADSKAN-VWYEF----------RGHRWHKMDDANELMRIISFELPEEFRVEINRLSAITGQSQDPNSQLTIKKC VD----IQSKLQMDGFSQGVMKMCKRLFLNEHFLSKLDENRDLLGMEDGVCDLK--LGIFRDGSPDDYISMSTGISYKALSEEDRSVIECREFLKKLFPN PRIRKCALRMVSSCMQGGNRNKRIYICTGKGNNGKSVFFSLLEYIFGQYLIKFPREMCLAGRAGNPSSARPELARAPGTRYGVIQEVHKNEKFNPGILKE LSGNDSFFVRNLFEKGRDIKPMFTIFMMANKPPGVPGSDQATWNRIRLIPFEATFLSEQDENwieDPELRREAKMFKADEHFEEKIPGLAHALLWLCVED FRKYKEEGL--CEPEEVEAATAKMRARNDTIRKYIRDCLIVDREkkeddektfltVSELFNHYKEWHDEN------------------------------ -------------------------- >UniRef50_A4KXH3(60-999:1052) ATPase n=2 Tax=Ascovirus RepID=A4KXH3_HVAVE E=2e-78 s/c=0.31 id=18% cov=34% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- --------------WKQCDPDEIRSMWlrDSANTPSGRRVTYASIFYDAKSDNADAYRILAESHRKELarirrkakAAVKATTRSAEPTTVSRKTSIARK RQTDIITADNSGvvakASAVRRRYRTDDDYDESESDEYDDDDEYDDYLHNrlnssnsqrlpgigggdgdlppgvQISDNELTQMDDTDFDIASMFVRDWg rcvtmvgkvmyqfngniwkpvrndEALIRKELPIWYDKFEEhvseylerlaesgmgavphgdedsnggrgpsvvtvakrkflsVRRKCKNSAPQSGVITQ IRALNTHDAGAyksTKMDDNDNIIAFKDMVFCRDTLT--LRKGTPEDMISRCLNCNYVPYDElTDEVRKFVNDFFTSLFPDPEVKEYFLLSVAQIFRGSN IFKQYMVWTGVGNNGKSVLIRMFECLLG------------------------------------------------------------------------ ---------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------- >UniRef50_B7KMX2(345-795:1000) Primase P4 n=1 Tax=Cyanothece sp. PCC 7424 RepID=B7KMX2_CYAP7 E=6e-29 s/c=0.29 id=18% cov=40% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -----------------------------------------------------------------------------------FNSSYLNGI----EELL RKALYIKEWPKAPNLLPFSDCVLELST--GKTREHSPNNWLTWVLPRPYNSLEKS--WIKIDNWLTEATLGNATHKQILLCYAAAVLRRRADLQKFLHLI GTGGSGKSTFMNLLVALVGQQNTISLDFNSLNEKD--------AVAEAFGKVLAIFPDQDSAGK-NISNFKKITGQDLLRGRRLYKDGFNFRFEGLCAVS SNHP--IFHSGSGRWltRRVLMVPFELAVPDGKVRNLEKEFEPELSAFTSYLLSIP-ESEIEATL--------------KGLNKKQVVSSTLWSSQIRSD GLASWVNDEIIFDSTArtqigsnakewgeddydaasSTLFGSYCRHIRRSGRqplTKDNFSANLIELLKGTLKRDVEKIKTNQGRFLTGVRL-------- --------- >UniRef50_Q54324(44-837:904) ORF904; Method: conceptual translation supplied by author n=3 Tax=Sulfolobus RepID=Q54324_SULIS E=1e-135 s/c=0.61 id=16% cov=77% -------------------FLEHGFNIIPIDPESKKP-VLKEWQKYSHEMPSDEEK---QRFLKMIEEGYNYAIPGGQK--GLVILDFESKEKLKAW--I GESALEELCRKTLC----------------TNTVHG--GIHIYVLSNDIPP---HKINPLFEENGKGIIDLQSYNSYvlGLGSCVNHLHCttdKCPWKEQ NYTTCYTLYNELKEISKVDLKSLLRFlaEKGKRLGITLSKTAKEWLEGKKEEEDTVVEFEELRKELVKRDSGKPVEKIKEEI---CTKSPPKLIKEIICE NKTYADvniDRSRGDWHVILYLMKHGVTDPDKILELLPRDSKAKEN-----------EKWNTQKYFVITLSKAWSVVKKYLEAKRKAQKDKSTAKALLI- ---------EAIAEEVLHEHFLVTFIQTD-----QLKESKIGLFR---FNKKKGIFEPFDERIEKII------NVKLEEYKEFPLGSDKSRVIRN--IKE EIMRRTQRLLLEESLR---------IAFRNGTLEWDSKGVTWYDVKERTP--KVYSFNYvDWNLKIEEIEKFnMKEITVEDIENLARRVCprsletfkqw vddkwvlLFEVIGYTFYPKYIFNKAILLTGAGANGKSTFLNLLLKILGQKNVSAMPLKRIMESDRFAS------IELFHKLANVSSELFAFKITNTDLFK KLTGEDYIEGQKKFRDPIYFINYAKLFNATNELPVVSDQSYGFWRRWIVIEFPHQFPPDPN----------------FFDKTFTVEEVEGVITVAVIAFA RVLQ-QKKFDFEDSSANVKELWERKTDSVYAFVKE----------------------------------------------------------------- ------------- >UniRef50_B6D7K5(291-632:635) Gp32 n=1 Tax=Listeria phage P40 RepID=B6D7K5_9CAUD E=5e-22 s/c=0.32 id=19% cov=26% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -----------------------------------------------------------------------------------------------LFIFI GKGGEGKGTMLTILRRILGDESVSASSIEDLTREQYLYS--------LTGKLANLCDDV-ENKPINDkkmKILKNISTCDRIELRKMREQSFPATLTCSL ILTSNHLLKSFEKGESWKRRVVWLPmFNRGF------------KKDPRFITKVTTPKALEY----WVRLMMEGYNRIIENG-QLTSSEKINKYNEEYERE NNNVIEYCDSITIDDIvglKPKAVYDKYTTWYEQEIGEKDKaLSAKIVKETVSSV------------------------------------- >UniRef50_A0K5A3(2-707:746) Phage/plasmid primase, P4 family n=4 Tax=Burkholderia RepID=A0K5A3_BURCH E=2e-86 s/c=0.46 id=18% cov=78% ---------YTDPIKKYSDLATKGFACFPIVPNEKRPLTPNGFKDAS--LDPEQHRAWAEQF-----PSSNIAYATGAPSGRLIVIDVDVKNNKSGA--- ----------KSLVALQKK----HGPLPATRTVITPSGGIHLLFTYPEG----MKIQCKVGFRDG---IDIRADGGY----------CGAP----PSTIE GN-PYEW-------VDETVPIAPAP-----------AWLLEEFAKQGTTRRKRKSRKTAIVPAGNRNQSVMLH----------------AFSLLN----- ----------------------------------------GGLDYERLEEELLEYNAACCNPPLSESEVSQVAVNVIRSH-----------------QEN SGSNQ----HTTDLGNARRMSDLFGDELRYVPQTKQWLKKRESGVWQRVDELHVLLLARQLLPLIYEELSRLSPGNRVEMFEHAKYTESNTGLKYAVELF RSEPGIAvsagDLDQGEWMLPVRNGLIDLRT--GSFMPMDPKLHITYTAAVDYDPDATCPLWEAFLLEIMNR---NVELVEYVRRAIGYTLTTLTSEHAL FFAFGSGANGKSTFLNVLRALFGDLGAQANGDMLLDKNGGaamSSNAASSEVARLAGKRLVAMSEVEEGRHFSEKTVKWYTGGEDITARLLYGNAFEFKP RFKLWLAGNYKPTIKGNDHGIWRRMKLIPFTVTIPP---------EKRDPDL------ERKLRDELPGILNWALVGCKQWRENGNKLNEPKAITNEVSEY RGEMDVVESWLSEFTRNDPDgeihFGDTYKFFKAWSESQYNFSYS-----GKRFGMILADKGYKPASKPHRVYKGLRLIV--------------- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * T 1 * * * * * * * * * * * * * * * * 0 * * * 1 0 * * * * * * 1000 0 0 I 2 * * * * * * * 0 * * * * * * * * * * * * 2 0 * * * * * * 1000 0 0 Q 3 * * * * * * * * * * * * * 0 * * * * * * 3 0 * * * * * * 1000 0 0 L 4 * * * * * * * * * 0 * * * * * * * * * * 4 0 * * * * * * 1000 0 0 T 5 * * * * * * * * * * * * * * * * 0 * * * 5 0 * * * * * * 1000 0 0 A 6 0 * * * * * * * * * * * * * * * * * * * 6 0 * * * * * * 1000 0 0 Q 7 * * * * * * * * * * * * * 0 * * * * * * 7 0 * * * * * * 1000 0 0 R 8 * * * * * * * * * * * * * * 0 * * * * * 8 0 * * * * * * 1000 0 0 K 9 * * * * * * * * 0 * * * * * * * * * * * 9 0 * * * * * * 1687 0 0 Y 10 * * * * * * * * * * * * * * * * * * * 0 10 0 * * * * * * 2163 0 0 L 11 * * 1593 * * * * * * 1339 * * * * * * 1872 * * * 11 0 * * * * * * 2163 0 0 A 12 460 * 1872 * * * * * * * * * * * * * * * * * 12 0 * * * * * * 2163 0 0 E 13 * * * 460 * * * * * * * * 1872 * * * * * * * 13 0 * * * * * * 2163 0 0 V 14 * * * * * * * 726 * * * * * * * * * 1339 * * 14 0 * * * * * * 2163 0 0 Q 15 * * * * * * * 1593 1872 * * * * 1339 * * * * * * 15 0 * * * * * * 2163 0 0 A 16 460 * * * * * * * 1872 * * * * * * * * * * * 16 0 * * * * * * 2163 0 0 L 17 1593 * * * * * * * * 1339 * * * * * * * * * 1872 17 0 * * * * * * 2163 0 0 E 18 1593 * * 1339 * * * * * * * * * * * 1872 * * * * 18 0 * * * * * * 2163 0 0 T 19 * * 1872 * * * * * 1593 * * * * * * * 1339 * * * 19 0 * * * * * * 2163 0 0 L 20 * * * * 2050 * * * 1974 988 * * * * * * * * * * 20 0 * * * * * * 2651 0 0 L 21 2263 * * * * * * * * 897 * * * * * * * * * 1974 21 0 * * * * * * 2651 0 0 T 22 * * * 2050 * * * * * * * * * * * * 399 * * * 22 0 * * * * * * 2651 0 0 R 23 * * * * * * 2050 * 1111 * * * * * 1758 * * * * * 23 0 * * * * * * 2651 0 0 E 24 1974 * * 1758 * 1153 * * * * * * * * * * * * * * 24 424 1974 * 0 * * * 2651 1000 0 L 25 * * * * 1153 * * * * 862 * * * * * * * * * * 25 0 * * * * * * 2651 0 0 S 26 2263 * * * * * * * * * * 2050 1974 * * 1758 * * * * 26 0 * * * * * * 2651 0 0 V 27 * 2263 * * * * * 1012 * * * * * * * * * 1758 * * 27 0 * * * * * * 2651 0 0 F 28 * * * * 399 * * 2050 * * * * * * * * * * * * 28 0 * * * * * * 2651 0 0 L 29 * * * * * * * * * 1758 * * 506 * * * * * * * 29 0 * * * * * * 2651 0 0 T 30 * * * * * * * 1153 * * * * * * * * 862 * * * 30 0 * * * * * * 2651 0 0 E 31 * * 2050 1758 * * * * 1974 * * * * * * * * 2263 * * 31 0 * * * * * * 2651 0 0 P 32 * * * * * * * * * * * * 0 * * * * * * * 32 0 * * * * * * 2651 0 0 G 33 * * * 2050 * 862 * * * * * 2263 * * * * * * * * 33 0 * * * * * * 2651 0 0 S 34 * * * 2263 * * * * * * * * * * * 337 * * * * 34 0 * * * * * * 2651 0 0 K 35 * * * * * * * * 0 * * * * * * * * * * * 35 0 * * * * * * 2651 0 0 K 36 * * * 1974 * * * * 897 * * * * * 2263 * * * * * 36 0 * * * * * * 2651 0 0 T 37 * * * * * * * * * * * * 506 * * * 1758 * * * 37 399 * 2050 * * * * 2651 0 0 N 38 * * 1593 * * * * * * 1872 * 1339 * * * * * * * * 38 0 * * * * 0 * 2163 0 1000 I 39 * * * * * * * 1758 * * * * * * * * 1111 2050 * * 39 0 * * * * * * 2651 0 0 I 40 * * * * * * * 1758 * 2050 * * 2263 * * * * 1974 * * 40 0 * * * * * * 2651 0 0 N 41 * * * * * * 1974 * 2050 * * 988 * * * * * * * * 41 0 * * * * * * 2651 0 0 R 42 * * * 2050 * 1111 * * * * * * * * 1758 * * * * * 42 0 * * * * * * 2651 0 0 I 43 * * * * 1111 * * 1758 * * * * * * * * * * 2050 * 43 0 * * * * * * 2651 0 0 T 44 * * * * * * * * 1111 * * * * 2050 * * 1758 * * * 44 0 * * * * * * 2651 0 0 G 45 * * 1111 * * 1758 * * 2050 * * * * * * * * * * * 45 0 * * * * * * 2651 0 0 K 46 1111 * * * * * * * 1758 * * * * * * * * * * 2050 46 0 * * * * * * 2651 0 0 T 47 * * * * * * * * * * * * * * * 1153 862 * * * 47 337 * 2263 * * * * 2651 0 0 Y 48 * * * * * * 1726 * * * * 1645 * * * * * * * 1404 48 0 * * * * * 0 2244 0 1000 A 49 1404 * 1645 1726 * * * * * * * * * * * * * * * * 49 556 * 1645 * * 0 * 2244 0 1000 L 50 * * * * * * * * * 557 1643 * * * * * * * * * 50 0 * * * * * 0 2118 0 1000 P 51 * * 1864 * * * * * * * * * 463 * * * * * * * 51 0 * * * * * 0 2118 0 1000 S 52 * * * * * * * * * * * * 1864 * * 463 * * * * 52 0 * * * * * 0 2118 0 1000 T 53 * * 1643 1864 * * * * * * * * * * * * 1303 * * * 53 0 * * * * * 0 2118 0 1000 E 54 * * * 463 * * * * * * * * * 1864 * * * * * * 54 0 * * * * * 0 2118 0 1000 L 55 * * * 1643 * * 1864 * * 1303 * * * * * * * * * * 55 0 * * * * * 0 2118 0 1000 L 56 * * * * * * * * 1643 1303 * * * * 1864 * * * * * 56 557 * 1643 * * * 0 2118 0 1000 R 57 1320 * * * * * * * * * * * * * 738 * * * * * 57 0 * * * * * 0 1560 0 1565 L 58 * * * * * * * * * 738 * * * * * * * * 1320 * 58 0 * * * * 954 1047 1560 0 1565 Y 59 1872 * * * 1593 * * * * * * * * * * * * * * 1339 59 0 * * * * 0 * 2163 0 1000 E 60 * * * 988 * * * * * * * 1974 * 2050 * * * * * * 60 0 * * * * * * 2651 0 0 H 61 * * * * * * 1758 * 1974 * * * * 2263 2050 * * * * * 61 0 * * * * * * 2651 0 0 L 62 * * * * 506 * * * * 1758 * * * * * * * * * * 62 337 * 2263 * * * * 2651 0 0 E 63 * * * 1404 * * * * * 1726 1645 * * * * * * * * * 63 0 * * * * * 0 2244 0 1000 Q 64 * * * * * * * * 1726 * * * * 519 * * * * * * 64 0 * * * * * 0 2244 0 1000 C 65 * 1404 * * * * * * * * 685 * * * * * * * * * 65 0 * * * * * 0 2244 0 1000 R 66 * * * * * * 1645 1726 * * * * * * 1404 * * * * * 66 0 * * * * * 0 2244 0 1000 K 67 * * * 2135 * * * * 932 * * * * * 2012 * * * * * 67 0 * * * * 0 * 2793 0 1000 Q 68 * * * 2362 * * * * * * * 2207 1452 2162 * * * * * * 68 0 * * * * * * 3134 0 0 G 69 * * * * * 246 * * * * * * * * * 2675 * * * * 69 0 * * * * * * 3134 0 0 A 70 2162 * 2260 * * * * * * * * * * 2207 * 2675 * * * 2362 70 0 * * 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* * 624 * * * 2675 * * * * 95 0 * * * * * * 3134 0 0 A 96 1258 * * * * 1422 * * 2260 * * * * * * * * * * * 96 0 * * * * * * 3134 0 0 V 97 2675 * * * * * * * 2260 * * * * * * * * 2162 2362 2207 97 624 * 1510 * * * * 3134 0 0 P 98 * * * * * * * * * * * * 0 * * * * * * * 98 0 * * * * * 0 2300 0 1506 P 99 * * * * * * * 1654 * * * 1589 1515 * * * * * * * 99 0 * * * * 884 1126 2300 0 1506 L 100 * * * * * * * 2135 2012 1906 * * * * * * * * * 1957 100 0 * * * * * 0 2793 0 1000 E 101 * * * 1906 * 1043 * * 2012 * * * * * * * * * * * 101 0 * * * * * 0 2793 0 1000 P 102 * * 2012 2135 * * * * * * * * 1906 * * 1957 * * * * 102 430 1957 * 4087 87 * 0 2793 1000 1000 P 103 * * * * * 2012 * * * * * 1957 1906 * * 2135 * * * * 103 0 * * * * * 0 2793 0 1000 A 104 411 * * * * * * * 2012 * * * * * * * * * * * 104 0 * * * * * 0 2793 0 1000 L 105 * * * * * * * * * 1016 * * * * * * * 984 * * 105 0 * * * * * 0 2793 0 1000 S 106 * * * 2135 * * * 2012 * * * * * * * 932 * * * * 106 0 * * * * * 0 2793 0 1000 R 107 * * * 1043 * * * * * * * * * * 958 * * * * * 107 0 * * * * * 0 2793 0 1000 L 108 * * * * * * * 2012 * 1016 * 1957 * * * * * * * * 108 0 * * * * * 0 2793 0 1000 C 109 * 1016 * * * 2012 * * * * * * * * * * * 1957 * * 109 0 * * * * * 0 2793 0 1000 H 110 * * * * * * 1906 * * 2012 * 1957 * * 2135 * * * * * 110 0 * * * * 0 * 2793 0 1000 R 111 * * 2260 * * * * * 1510 * * * * * 1184 * * * * * 111 0 * * * * * * 3134 0 0 I 112 * * * * * * 2207 2162 * * * 2260 * * * 2675 2362 * * * 112 0 * * * * * * 3134 0 0 F 113 2207 * * * 2162 * * * * 837 * * * * * * * * * * 113 0 * * * * * * 3134 0 0 V 114 * 1310 * * * * * * 2207 * * * * * * * * 1395 * * 114 312 * 2362 * * * * 3134 0 0 H 115 2379 * * * * * 1826 * 927 * * * * * * * * * * * 115 0 * * * * * 0 2682 0 1000 I 116 * * * * * * * 1826 * 1115 * * * 1964 * * * * * * 116 0 * * * * * 0 2682 0 1000 K 117 * * * * 1964 * * * 1826 * * * * 2379 * * 1891 * * * 117 0 * * * * * 0 2682 0 1000 N 118 * * * * * * * * 2379 * * 308 * * * * * * * * 118 0 * * * * * 0 2682 0 1000 S 119 * * * * * * * * 1115 1964 * * * * * 1826 * * * * 119 308 * 2379 * * * 0 2682 0 1000 S 120 * * * * * * * * * 1654 * 1589 * * * 1515 * * * * 120 583 1589 * 2000 415 * 0 2300 1000 1506 V 121 * * * * * 1654 * * * * * * * * * * * 551 * * 121 0 * * * * * 0 2300 0 1506 L 122 * * * * * * * * * 0 * * * * * * * * * * 122 0 * * * * * 0 2300 0 1506 I 123 * * * 621 * * * 1515 * * * * * * * * * * * * 123 0 * * * * 1126 884 2300 0 1506 H 124 * * 1964 * * * 1077 * 1891 * * * * * * * * * * * 124 0 * * * * * 0 2682 0 1000 F 125 * * 1891 * 1826 2379 * * * * * * * * * 1964 * * * * 125 0 * * * * * 0 2682 0 1000 F 126 * * * * 1826 * * 1891 1964 * * * 2379 * * * * * * * 126 0 * * * * * 0 2682 0 1000 F 127 * * * * 859 * * * * 1157 * * * * * * * * * * 127 0 * * * * * 0 2682 0 1000 T 128 * * * * * * * 1891 * * * * 2379 1964 * * 1826 * * * 128 0 * * * * * 0 2682 0 1000 L 129 2379 * * 1891 * * * * * 1826 * * * * * * 1964 * * * 129 0 * * * * * 0 2682 0 1000 K 130 * * * * * * * * 1826 1964 * * * * 1891 * 2379 * * * 130 0 * * * * 0 * 2682 0 1000 P 131 * * * * * * * 2207 * * * * 2162 * 2675 * 2362 2260 * * 131 0 * * * * * * 3134 0 0 E 132 * * * 2162 * * * * * * * 1282 * * * * 1452 * * * 132 0 * * * * * * 3134 0 0 V 133 * * * 1233 * * * * * * * * * * * * 2362 1395 * * 133 0 * * * * * * 3134 0 0 V 134 * * * * * * * 2675 * * * * * * * 2207 2260 1258 * * 134 0 * * * * * * 3134 0 0 Q 135 * * * 2207 * * 2362 * * * * * * 1210 * * 2675 * * * 135 0 * * * * * * 3134 0 0 G 136 * * 2207 * * 1258 * * * * * * 2675 * * 2260 * * * * 136 312 * 2362 * * * * 3134 0 0 K 137 * * * * * 1964 * * 859 * * * * * * 2379 * * * * 137 427 * 1964 * * * 0 2682 0 1000 Y 138 * * * * * 1968 * * * * * * * * * * * * * 426 138 645 1472 * 2000 415 0 * 2135 1000 1565 G 139 * * * * * 0 * * * * * * * * * * * * * * 139 0 * * * * * * 3134 0 0 F 140 * * 2260 * 2162 * * 817 * * * * * * * * * * * * 140 0 * * * * * * 3134 0 0 H 141 * * * * * * 0 * * * * * * * * * * * * * 141 0 * * * * * * 3134 0 0 V 142 * * * * 2260 * * 2362 * 1422 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0 T 166 * * * * * * * 2012 2135 * * * * * * * 1906 1957 * * 166 0 * * * * * 0 2793 0 1000 V 167 * * 2012 * * 2135 * * * * * * * * * * * 932 * * 167 0 * * * * * 0 2793 0 1000 Q 168 * * * * * * * 2135 984 * * * * 1906 * * * * * * 168 0 * * * * 0 * 2793 0 1000 K 169 * * * * * * * 1510 2162 * * * * * * * 2207 2260 * * 169 0 * * * * * * 3134 0 0 I 170 * * 837 * * * * 2162 * * 2207 * * * * * * * * * 170 0 * * * * * * 3134 0 0 L 171 * * * * * * * 781 * 1258 * * * * * * * * * * 171 0 * * * * * * 3134 0 0 H 172 * * 2207 * * * 2162 * * * * * * 1310 2675 * * * * * 172 0 * * * * * * 3134 0 0 E 173 1452 * * 2162 * * * * * * * * * 2207 * 2362 * * * * 173 0 * * * * * * 3134 0 0 Q 174 * * 2675 1233 * * * * * * * * * 2162 * * * * * 2362 174 0 * * * * * * 3134 0 0 G 175 * * * * * 764 * * * * * 1282 * * * * * * * * 175 0 * * * * * * 3134 0 0 V 176 2260 * * * * 2675 * * * * * * * * * 2362 * 1184 * * 176 0 * * * * * * 3134 0 0 T 177 * * * * 2207 * * * * * * * * * * * 2162 * * 837 177 1184 2362 1452 1000 1000 * * 3134 1000 0 N 178 * * * * * 1742 * * * * * 1475 * 1551 * * * * * * 178 602 1551 * 3459 138 * 0 2250 1000 1532 P 179 * * * * * * * * * 1742 * * 512 * * * * * * * 179 0 * * * * * 0 2250 0 1532 E 180 * * * 996 * 2012 * * * * * * * * * 1997 * * * * 180 0 * * * * 847 1171 2685 0 1532 S 181 * * * * * * * * 2439 * * * * * * 714 * 2279 * * 181 0 * * * * * 0 3187 0 1000 C 182 * 754 * * * * * * * 2315 * * * * * * * 2279 * * 182 0 * * * * * 0 3187 0 1000 L 183 * * * * * * * 1901 * 783 * * * * * * * 2727 * * 183 0 * * * * * 0 3746 0 1000 D 184 * * 516 * * * * * * * * 2727 2739 * * * * * * * 184 0 * * * * * 0 3746 0 1000 P 185 * * 2832 * * * 2727 * * * * * 783 * * 2974 * * * * 185 0 * * * * * 0 3746 0 1000 H 186 * * * * * * 2842 2832 * 1150 * 3064 * * * * 2739 * * * 186 0 * * * * * 0 3746 0 1000 S 187 * * * 2739 * * 2727 * 2974 * * * * * * 806 * * * * 187 0 * * * * 0 * 3746 0 1000 A 188 2998 1000 * * * 2005 * * * * * * * * * 2991 * * * * 188 211 2876 * 1585 585 * * 4007 1000 0 S 189 * * * * * 3298 * * 968 * * * * * 3215 2998 2696 * * * 189 176 * 3124 * * * * 4007 0 0 V 190 3145 2727 * * 2746 * * * * * * * * * * * * 1187 * 2760 190 230 * 2760 * * 0 * 3796 0 1000 P 191 * 3037 * * * 2730 * * * * * * 459 * * * * * * * 191 186 * 3051 * * 0 * 3714 0 1000 S 192 * * * * * * * * 2739 * * * * * * 2842 * * 493 * 192 0 * * * * * 0 3746 0 1000 L 193 * * * * 3064 * * * 2727 787 * * * * * * * * * 2739 193 0 * * * * * 0 3746 0 1000 L 194 * * * 2727 * * * 3064 2739 2842 1901 * * * * * * 2536 * * 194 0 * * * * * 0 3746 0 1000 Y 195 * * * * 2739 * * * * * * * * 2727 * * * * * 516 195 0 * * * * 0 * 3746 0 1000 G 196 * * * * * 672 * 2895 * * * 2876 3298 * * * * * * * 196 0 * * * * * * 4007 0 0 S 197 1932 * * * * * * * * * * * * * * 1097 2895 * * 2876 197 0 * * * * * * 4007 0 0 S 198 * 3215 2895 * * * * * * * * * * * * 1303 1504 * * * 198 0 * * * * * * 4007 0 0 K 199 * * * * * * * 3298 672 * * * * * * * 2876 2895 * * 199 0 * * * * * * 4007 0 0 L 200 * 2876 * 2137 * * * * * 2998 * * 968 * * * * * * * 200 115 * 3709 * * * * 4007 0 0 N 201 * * 3057 * 2847 1084 * * * * * 2938 * * * * * * * 2851 201 417 2931 3057 0 * 0 * 4005 1000 1000 H 202 * * 1424 * * * 2914 * * * * 1495 * * * * 2839 * * * 202 366 3069 3251 2322 322 0 * 3987 1000 1000 K 203 * * 3064 1153 * * * * 1837 2727 * * * * * * * * * * 203 234 2739 * 2000 415 0 * 3746 1000 1000 P 204 * * * * * * * * * * * * 403 * * 3215 * * * 2876 204 0 * * * * * * 4007 0 0 Y 205 * * * * 2696 * * * * 2895 * 2876 * * * * * * * 798 205 0 * * * * * * 4007 0 0 Q 206 2696 * * 1426 * * * * 2991 * * * * 2102 * * 3124 * * * 206 0 * * * * * * 4007 0 0 L 207 * * * * 2895 * * 1522 * 1936 * * * * * * * * 1966 * 207 155 * 3298 * * * * 4007 0 0 K 208 * * * * * * * * 780 * * * * * * 1901 * * * 2739 208 273 2536 * 2807 222 * 0 3746 1084 1000 T 209 2536 * * 2727 * * * * 2832 * * 2739 * 2974 * * 2842 * * 3064 209 0 * * * * * 0 3746 0 1000 G 210 * * * * 2739 1681 * 1779 * * * * * * * * * 2018 * * 210 0 * * * * * 0 3746 0 1000 F 211 * * * * 1290 * * * 2536 2832 * * * * * 2727 * * * 2974 211 196 2974 * 2322 322 * 0 3746 1000 1000 E 212 2739 * 1943 1907 * * * * 2727 * * * * * * * 2536 * * * 212 218 2832 * 4087 87 * 0 3746 1000 1000 L 213 * * * * * 2739 * 1184 * 2842 * * * * * 3064 * 2727 * * 213 0 * * * * * 0 3746 0 1000 V 214 * * 758 * * * * * * * * * * * * 3064 2739 2842 * * 214 0 * * * * 0 * 3746 0 1000 F 215 * * * 2895 1839 2099 * * * 2876 * * * * * * * 2208 * * 215 194 2991 * 2000 415 * * 4007 1000 0 D 216 * * 1097 * * * * * 1402 * * 2696 * * * * * * * * 216 0 * * * * * * 4007 0 0 S 217 * * * 3298 * * * * 2895 * * * * * * 1047 1836 * * * 217 176 3124 * 1585 585 * * 4007 1000 0 S 218 2696 * 3215 3124 * * * * * 2876 * 2991 * * * 1946 3298 * * * 218 242 2696 * 1000 1000 * * 4007 1084 0 D 219 * * 1369 2005 * * * * * 2876 * * * * * * * 2137 * * 219 164 3215 * 2322 322 * * 4007 1000 0 P 220 3124 * * 2991 * * * * 3215 * * 2895 2140 * 2876 * * 2696 * * 220 0 * * * * * * 4007 0 0 D 221 * * 1053 2696 1933 * * 3298 * * * * * * * * * * * * 221 211 2876 * 1000 1000 * * 4007 1000 0 Y 222 2083 * * 1408 * * * * * * * * * * * * 1932 * * 2998 222 0 * * * * * * 4007 0 0 I 223 * * 2895 * * * * 2998 2876 2099 3124 * 1966 * * * * * * * 223 0 * * * * * * 4007 0 0 P 224 3298 * 3124 * * 2876 * * * 2895 * * 1303 * * * * * * 3215 224 0 * * * * * * 4007 0 0 I 225 * * * * * * * 1946 2876 3124 2991 * 2256 * * 2696 * * * * 225 155 * 3298 * * * * 4007 0 0 H 226 * * * 1852 * * 2842 * * 2832 * * * * 1886 * * * 2536 * 226 0 * * * * * 0 3746 0 1000 Q 227 * 3064 * * * 2536 * 2974 * 1779 * * * 2842 * * * * * 2739 227 0 * * * * * 0 3746 0 1000 I 228 * * * * 3064 1733 * 2842 2536 * * * 2974 * * 2832 * * * * 228 0 * * * * * 0 3746 0 1000 K 229 * * * * * 1892 * 1779 1907 * * * 2536 * * * * * * * 229 0 * * * * * 0 3746 0 1000 N 230 * * 2974 1892 * * * * * * * 1837 * * * * 1628 * * * 230 0 * * * * * 0 3746 0 1000 L 231 * * * * * * * * * 1259 * * 2832 * * 2536 3064 * * 2739 231 196 2974 * 3322 152 * 0 3746 1000 1000 E 232 * * 2536 1907 * * 2739 * 1943 * 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