HHsearch 1.5 NAME c6xr8C_ FAM FILE c6xr8C_ COM /bmm/www/servers/phyre2/HH/hhmake -i c6xr8C_.a3m DATE Sat Jul 25 08:38:10 2020 LENG 1107 match states, 1107 columns in multiple alignment FILT 22 out of 26 sequences passed filter (-id 90 -cov 0 -qid 0 -qsc -20.00 -diff 100) NEFF 3.8 EVD 0.3009 -11.4184 SEQ >ss_dssp CCCCCCCCCCCCCEEEEESSCCCBCSSSCCCCSEEEEEEEEECCTTEEEEEEEEECCEECCCCEECCSCEEEEEEESSSCEEEEEEESSCBSSSCEEEEE EETTEEEEEEEEEEEEEEEEEEEECSCSSSCCEEEEEEEEEEEEEEEEEEECCCCCCCCCCCCSSEEEEEEEEEEEETTEEEEEEEEEEEEESSSCCSCC CCBEEEEEECCCCCCCEEEEEEECCCSCCCCCSEEEEEEECEEEEEEEEECTTCCEEEEEETTSSHHHHHHHHHTCSCCCSEEEEECCCCCCCSEECCBC CCCCSBCCHHHHSSCSSCCBGGGCEEEEECSEECCGGGGTTTCCCSEEEESSSCGGGGGGCCBSSEEEEEEEEEGGGGGGGSSSCCSHHHHHTCCCCTTC CEEEEEEECHHHHCCTTCBCCCEEECCCSSCCCTTCCCCCCCCEECSSSCCCSSCBTTEECSEEECCBCTTSCTTSSEEEEEEEECCCSSSCCSEECSCC CCCCCCSSEEEEEETTEEEEEEEEECCCCCCTTCCEEECTTCCEEEEECSSSCCEEEEECSCCCCEEEEECCTTTCSCCEEEETTCCCCCCCSSCCSSEE EETTEEEESCEECSSCCCCSEEEETTEEEEEECCCEEEEEECCCCCCCCCCCCTTEEEEESSEEEEEEEEEEECCCCEEEECHHHHHSTTCHHHHHHHTT TTTHHHHHHHHHHHHHHHHHHHHHHHHTTCSSCCCCCSSCCSTTCCGGGTSBCTTSSSCCBHHHHHHHHHSCCSCCTTCCCSGGGSTHHHHHCHHHHHHH TTEEEECCSSCHHHHHHHHHHHHHHHHHHTTHHHHSSCCCCCHHHHHHHHHHHTTCCTHHHHTTHHHHHHHHHHHHHHHHHHHHHCSGGGHHHHHHHHHH HHHHHHHHHGGGCCTTSSCSCHHHHHTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSSCCCSTTSSSSSEEEEEEEEE ETTEEEEEEEEEEECCEEEEECCSCEESSSSEEEESSSEEEESSSCEEEECTTSCCCEECBTTTEEECSCTTTSTTCEECCCBCTHHHHHHHHHHHHHHH HHHHHCC >sa_dssp EDCDAEDCDEEEECEBDACCBAAACCDEEECCDDDCDCECCAABBDCEACCBCBDEDBABBDDBDBEEBAAAAAABBCDBBABBAAACCBDCECCAAABA CCBDCCBBCAACADBBEBAAAACDEEDEEEDDDCDCDBACDDDEEDECDDDCEECEDEBDCEDEDBDDACABAABCDEDEACBBBCECEBEDEEDABECC CAADDEDDBDBEBEBDDABAAABCEDDECEBCDBBAAABCADECCAAADBCEEBDBDDBBACEDDCBBBBBBDDECCEAEDCCCEBDEBEDECDDEACBA BECEDDBCCEEBCECEEBCCACCADCDDBDDACCCCDDBEEECECDDDDBCDCDDEEBCCBABBDBCAABAAACCEABEBACCEDECCAACCAACBCEEB CAABAABDACEEBCEEEBCDEBCBBCCCEDEBEDCCDCDDDECCDDDEEECEEEDDEDBDDBBDCABADDEBDEBDBACBAAACBBDBCEDDCDBBBDDE CDECCCEEBADBBABBBECDACACECEDEBEEEDBBCDDEEEECCAACABCEEDBACBDEBDEBBAAAAABCCEECEDCABAACEBEBEEDCDDECEDDC CBECBAABCADDCEEDDECDBEBDEDBAABCCEEDCBBAADDDEEEEEEEEEDEDDCDABCCADBCBDCCCBBABACBBCBDBDDAABCEBEDACECBEE CDEDCDDBCECBDDBBECACDABDDAABCBEEDCECDEEDEBDEBDBDCABCCEEDECEBADABCCABECBEDECEEDEDEEEDBDEEDCEDCEBACBCD CBACCDDDECDDDDBBDBACAAAAAAACABDCBDEDEDEECEBBDBAADAADCBDADDCAADECCEDABECBCDBACEBCEDBEEDEEDBDEACDBBDCA CECBCDACEDBEDDDEBDBCDBDDACEECDEEDBDDCADDAADBBBEBACDBBDDADEBADDBDECADDABDBADDAACCBBEDEEBACEDDBAAAAAAA BBCBAAAAABAACDDEEDEBDCBDAABCEEDAACBEEBCAABDEEECCBBBECBCCDDEABDECADDEEDCEECEECCECEADDCEEDEEDDEDDDECEE EEEEEEE >ss_pred CCCCCCCCCCCCCCCEEEECEEEEECCCHHHHHCCCCEEEEEEECCCCCEEECCCCCCCCCCEEEEECCEEEEEECCCEEEEEEEEEECCCCEEEEEEEE CCCCEEEEEECCEEEECCCCCCEEECCCCCCCCEEEEEEEEEECEEEEEECCCCEEEEECCCCCCCCEECEEEECCCCCEEEEEECCCCHHHCCCCCCCC EEEEEEEEEEEEEEEHHEEEECCCCCCCCCCCCEEEEEEECCCEEEEEEEECCCEEEEEEEECCCCHHHHEEECCCCCCCCCEECCCCCEEEECEEEEEE CCCCCCCCCEEEECCCCCCCCCEEEEEEEEEEECCCEEEECCEEEEEEEECCCCHHHHCCCCCCEEEEEEEEECCCCEEEEECCCCCCEEEEEECCCCCC CCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCEEECCCCCCCCCEEEECCCCCCCCCCC CCCEEECEEEEEEEEEEEEEEEEEEEEEEEECCEEEEEECCCCEEEEEECCCCCEEEEECCCCCCEEEEECCCCCCCCEEEEEEEEEEEEEEEEEECCCC CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEECCCEEEEEEEEEEEEECCCEEEEECEEECCCCHHHHHHHHH HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHCCEEEECCCCCHHHHHHHCCCCHHHHHHHEEEE CCEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC CCCEEEEEEEEECCCCEEEEEEEEEEEECCEEEEECCCEEEEECCEEEEEECCCCCCCCCCCCCEEEEEEEEEEEEECCHHHCCCCCCCCCCHHHHHHHH HHHCCCC >ss_conf 9111121243782110000004760771111000000001332011220254046787667634542432787514760465257630465237799970 7700155542231331277664043277885412320035530101566315526897315620110000012124451489985257023202366541 1346688888666641135520233433454311245662224068999824750788885056615442110014567897101577612200168982 4666766520132477677531011246640001310332120342110034250320343122046788984265202230366652011100145643 4114531202455566544114333302667663221223334556654212210137898766521345541010233212110034126764113468 7401323025688610688999982000175060589823885678862357607999516655426785056677631589840024699864203655 4331025534315776543543223211444466505874312677642331246225434126788878998643525996120440883799999999 9899899999998855553577899885301330202212357754022125854666520433221022575176305557754178003311000013 4337626767888988989999998850001100133344627878887515011228889987999999999999999988899999999999999754 8999999999751112468789999999986665201346556679999999999999999999999999999999975111101534687689997024 9981899999754687599998655665380666318648986897999440211541576445699821268999656233654377766868899998 7204786 >Consensus xxxxxxxxxxxxxxyxxxxxxxxyxpxxxxrxxxxxxxxxlxxxxxxxxxxfxxxxxxxxxxxxxfnxgxxfxxxxxsxxvxgxxxxxxxxxxxxxlxxv xxxxxxxxxxcxxxxcxxxxxxxxxxxxxxxxxxxxxxxxxxxxnxxxxxxxxxxxxxxxxxxxxfxxxxxxxfxxxxxxxyxxxxxxxxxxxxxlpxxx xxxxxxxxxxxxxnxxxxxxxxxixxxxxxxxxxxxxvxxlxxxxxlLaydvnGTitxaVdCxxspxxxLkCxxxsfxxxxGfYpxsxxxxxxxxxxvxx pxxxxxcxxxxxxxxxxxpsxxxwkrxxxsNcnxnxtxlxsxtxfxxfxcxnvsxxxlxxlcxxsxxxdxxxixxxxxxxxxxxxxgxlxtfNyklxxxx tsCxlxxxxxxxxxxxxsxxFxlxxxxnxxxxxxxxxxxsxxxxxxxxxxxxxxxxxnxxxxlxxyxxxxxxgixyxxxtxxvxxxxivxxxxtvcxxxx xsxixxdxCvxYnIYGxtGxGvixxxnxxxxxxgxxxxxxsgxLxxfknxxtgxxyxVxPCxxxxxxvvxxxxxxxxxxaxxxxxixxsxxxxxtxxxxx xxxxgxxxxxxxxxxxxxCxxpigxxxcxxxxxxxxxxxxxxxxxxxxxxxxxxxnVxIPtnFtlsvtxEyiQxxxxkvsIDCaxYVCnxnxxCxxLLxq YgsfCxxIexaLxxxaxledxxxxxmxxxxxxxxxlxxixxfxxxnfsxiLxxpxxxxgRSaIEDLLFdKVxtsglGtvddYkxCtxgxxiaDLxCAQyY NGImVLPgVvdxexmAmYTasLxggmxxggxTaaaxxaxxiPFaxxvQaRlNylalttxVLxeNQkiiAnsFNxAigxIqxgfxtvsxALxKIQdVVNxq xxALxxLxxQLsnNFgAISSSixdIyxRLDxleAdaQVDRLItGRLxaLnayVtqxLxxxxevrxSrxLAxqKiNECVKSQSxRygFCGNGtHixSlxqx APnGixFxHxxlvPtxxvxVxaxxGlCvxxxxxvxkxgxfvxxnxxwxiTxrxxyxPrxiTxxdxvxixsCxVxyxnxtxxxlxxxxPdxxDfxxelxxx xxNxtsp >c6xr8C_ QCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQTLLALSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRF PNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDF TGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKK STNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTWRVYSTGSNVF QTRAGCLIGAEHVNNSYECDIPIGAGICASYQTSQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQ YGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKF NGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQN AQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQS APHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKY FKNHTSP >UniRef50_Q7TE91(251-1358:1481) S protein n=104 Tax=Coronavirinae RepID=Q7TE91_9ALPC E=0 s/c=0.95 id=26% cov=93% --------------YVQFVNKTTYY---TYNNTGGTGVNQLQLGLCEDdfcagyvTNVFTPVNGKIPGDF-SFNN--WFLLSDKSTIVQGRVV-SSQPVY VECLRPVPSWSNnsAIVSFDNDTFCpqasadvlrfNLNFSGEVFHPNATADDQIIFTFEDNSTAEISCYNGAN----VTDPTIGFNTTSQIPFGGTADPY LCFVNFSTAALDNQflgiLPPTIREMAFGRDGSIFINGYKYFNMPPIKSINFAISAVEYYgfwtIAYTKYTDVMV--DVNGTSITRLFYCDSPLNRIKCQ QMKHELPDGFYSANS------------------------LVKKNLPKTFVTTPQFYNGMNVTLHVILNDTSAGT-KVVGFERYELE-----QIADILFEI PQNQDGEVKNVTNFCVQTRQLAFFFKYTSLQgLYSISNTVWLKNYDCPFSPQQFNNYLQFETLCFDTNPSVAGCKWAVMH-SPIWNTQFATITVTYKEGA --------------QITTMPKPQLGFRDVSFKVEGECTDYNIYGFQGTGIIRKTESKLVA-GLFYTSASGDLLAFKNSTTGEIFTVVPCDLTAQAAVINd eivGAITSINQTDLFEFVNHTHTVrrvrravqTGTTITAYSMPQFYYITKWNNDTSENCTSVITYSsfaICNTGEIKFVNVTKveAVEDGIGTVKPISTG NITIPKNFTVAVQAEYIQIQVKPVVVDCAKYVCNGNNHCNRLLTQYTSACQNIENALNLGARLESLMLNEMITVSDSSLELATIEKFnttvvggeklGGI YFDGLKDVlPAQPGGRSAIEDLLFNKVVTSGLGTVDeDYKKCSAGTDIADLVCAQYYNGVMVLPGVVDDNKMAMYTASLIGGMAMGSITSA----VAIPF AMQVQARLNYVALQTDVLQENQKILANAFNNAMGNItlalgqvsdaistvSEGFNTMASALTKIQSVVNQQGNALSQLTQQLQNNFQAISSSIAEIYNRL EKVEADAQVDRLITGRLAALNAYVAQTLTQYTEVKASRQLAMEKVNECVKSQSDRYGFCGNGTHLFSLANAAPDGLLFLHTVLLPTEWEEVTAWSGICVN DtYAYVLKDfkSSIFSYSGTYMITPRNMFQPRKPQMSDFVQITSCEVTFLNTTYTTFEEIVIDYIDINKTisdmLEQYSPNFTIP >UniRef50_A3EXD0(213-1245:1352) Spike protein S2 n=12 Tax=root RepID=SPIKE_BCHK5 E=0 s/c=0.92 id=36% cov=86% ---------------------------------------------------------------------------------------------------- ------------------------------------FKVYFDLINCTFRY---NYTITEDENAEWFGITQD----TQGVHLYSSRKE---NVFRNNMFHF ATLPVYQKILYYTVIPRSIRSPFNDRKAW----AAFYIYKLHPLTYLLNFDVEGYITKAVDCGYDDLAQLQCSYESFEVETGVYSVSSFEASPRGEFIE- QATTQECDFTPMLTGTP-PPIYNFKRLVFTNCNYNLTKLLSLFQVSEFSCHQVSPSSLATGCYSSLTVDYFAYSTDMSSYLQPGSAGAIVQFNYKQDFSN PTCrVLATVPQNLTTiTKPSNYAYLTECYKTSAYG--KNYLYNAPGAYTPCLSLASRGFSTKYQSHSDGELTTTGYIY-PVTGNLQMAFIISvqygtDTN SVCPMQALRNDTsiedkLDVCVEYSLHGITGRGVFHNCTSVGLRNQRFVYDTFDNLVGYHSD-NGNYYCVRPCVSVPVSVIY--DKASNSHATLFGSVAC SHVTTmmsqfsrmtktnllaRTTPGPLQTTVGCAMGFINSSMVVdECQLPLGQSLCAIPPTTSSRVRratsgasdvfqiATLNFTSPLTLAPINSTgfvV AVPTNFTFGVTQEFIETTIQKITVDCKQYVCNGFKKCEDLLKEYGQFCSKINQALHGANLRQDESIANLFSSIKT-QNTQPLQAGLNGDFNlTMLQIPQV TTGerkyRSTIEDLLFNKVTIADPGYMQGYDECMqqGPQSARDLICAQYVAGYKVLPPLYDPYMEAAYTSSLLGSIAGASWTAGLSSFAAIPFAQSIFYR LNGVGITQQVLSENQKIIANKFNQALGAMQTGFTTTNLAFNKVQDAVNANAMALSKLAAELSNTFGAISSSISDILARLDTVEQEAQIDRLINGRLTSLN AFVAQQLVRTEAAARSAQLAQDKVNECVKSQSKRNGFCGTGTHIVSFAINAPNGLYFFHVGYQPTSHVNATAAYGLCNTenpQKCIAPIDGYFVLNQTTs tvadsdqqWYYTGSSFFHPEPITEANS-KYVSMDVKFENLTNRLPPPLLSNstDLDFKEELEEFFKNVSS- >UniRef50_B2BW33(473-1343:1472) Spike protein n=1 Tax=Beluga Whale coronavirus SW1 RepID=B2BW33_9GAMC E=0 s/c=0.81 id=26% cov=73% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------------------------FISTLNYTTALVTFD-KGNVRSVIDCnSEKPFDRLRCDLQTDVVSDGFYPVNikTNEAKENTTF IDVPATLANLTLEVFVSSPEQSPACVIKSYKCVDTRYFYISDYSYSCAE-----NGIPNDAAGAAYCRGVLDQINNYGVRGMDFKGK------------- -----CPFAGSKVNSGLTFDKICFGVYE------------QGCQSDKACRFGFYFDNVQFSQYGNKLYYKPQDLGFIDYQFGT--LFKNSLVQ------- ----SNIIQEGCHDYDIYGYKGTGVVKPFSdySYLQTGGLIMLDSGGFPSLFR--YNFALYEVTQCTREVAQLAVASNNAIGyylPKQVTIDGVNASTSC NTTGafkYCYYDDVIHVGRDVSNVTiNVCNPSLMMENSHCINIQGNFMVNEPAITFNSTQYQPLlgVSGDVQLPRTLMLHTTTEFIQTHSPKIVIDCTKY VCGSSERCRRILVKYGGFCESIMRLLNGVNMADDvsvTDFLDNFNSFDNISVSlqnlnASFGQFEGYGFQKFLPKSFDFDGsdprdaRSTIEDILFDKVT TVGLGTVDaDYDKCTKGLSVADLVCAQYYNGIMVLPGVADAEKMAMYTGALVGGMVLGGITSAAA----IPFATQIQARVNYLALTQNAIQENQKIIVQQ FNKAIDSMTsafqsvnEGFSAVSSAITEVQNAVNAQSQALTKLLGQLNYNFGATTSSIKELYERLAKLEADVQVDRLINGRLTALSAFVAARQVEAAKVA SQRVLAAEKINECVKSTSNRYGFCGNGAHIISFPQNAPNGMLFVHFSLVPNETITVKGIIGLCLNNSIGIVPAkdrGMFIQCSNGTYcpefensfneskn gnvtfpfaITSREQYNPRQITTGDIQMLTSCNSGYTHIEWSQLPLVAPPYDDFDKEFDKLYE----- >UniRef50_P17662(208-550:550) Spike protein S2 (Fragment) n=145 Tax=Infectious bronchitis virus RepID=SPIKE_IBVD3 E=6e-14 s/c=0.24 id=16% cov=21% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -----------------------------------------------LAYFVNGTAQDVILCDGSPTGLLACQYNTGNFSDGFYPFTN------------ ------------------SSLVKEKFIVYRESSVNTTLELTNFTFSNVSNANPNT--------GGVHTIQLYQTSTAQSGHYNFNFSFLSSFTYKESDYM YGSYH-----------PSCKFRLETINNGLWFNSLSVSLGYGPIQGGCKQSVFQNRATCCYAYSYNGPPLCKGVYRGELTKSFECGLLVFVTKTdgsriq trnepfTLTQHNYNNITLDRCVEYNIYGRVGQGFITNV-------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------- >UniRef50_Q8BB25(67-1242:1349) Spike protein S2 n=85 Tax=Betacoronavirus RepID=SPIKE_CVP67 E=0 s/c=0.82 id=34% cov=94% -----------------------YYPisGATFRNMALKGTRLL------STLWFKP-------PFLsPFNDGI-FAKVKNSRFSKDGVIYSEFPAITIGS TFVNTSYSIVvephtslingnlqgllqISVCQYTMCEYPH--TICHPNLGNQRIELWHYDTDVVSCLYR---RNFTYDVNADYLYFHFYQE------GGT FYAYFTDTGF-----------VTKFLFKLYLGTVLSHYYVMPLTCNS---ALSLEYWVTPLTTRQFLLAFDQDGVLYHAVDCASDFMSEIMCKTSSITPP TGVYELNGYTVQPVATVYRRIPDLPNCDIEAWLNSKTVSSPLNWERKIFSNCNFNMGRLMSFIQADSFGCNNIDASRLYGMCFGSITIDKFAIPNSRKVD LQVGKSGYLQSFNYKIDTAVSSCQLYYSlpaaNVSVTHYNPSSWNRRYgfnnqsfgsrglhdavysqQCFNTPNTYCPCR-TSQCIGGAGTGTCpvgttv rkcfaavtkatkctcwcqpdpstyKGVNAWTCPQSKVSIQPgqhcpglglveddcsgnpctcKPQAFIGWssetclQNGRCNIFANFILNDvnSGTTCST dlqQGNTIITTDVCVNYDLYGITGQGILIEVNATYYNsWQNLLYDSSGNLYGFRDYLSNRTFLIRSCYSGRVSAVFHAN--SSEPALMFRNLKCSHVFNN TIlrqiqlVNYFDSYLGCVVNAYNNTASAvsTCDLTVGSGYCVDYVTAlRSRRSFTTGYRFTNFEPFAANlvndsiepvgglyEIQIPSEFTIGNLEEFI QTRSPKVTIDCATFVCGDYAACRQQLAEYGSFCENINAILTEVNELLDTTQLQVANSLMNGVTLSTkIKDGINFnvddiNFSPVLgclgSECNRASTRSA IEDLLFDKVKLSDVGFVQAYNNCTGGAEIRDLICVQSYNGIKVLPPLLSENQISGYTLAATAASLFPPWTAAAG----VPFYLNVQYRINGLGVTMDVLS QNQKLIASAFNNALDAIQEGFDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISASLQEILSRLDALEAKAQIDRLINGRLTALNAYVSQQLSDSTL VKFSAAQAIEKVNECVKSQSSRINFCGNGNHIISLVQNAPYGLYFIHFSYVPTKYVTAKVSPGLCIAGDIGIsPKSGYFINVNNSWMFTGSSYYYPEPIT QNNVVVMSTCAVNYTKAPDLMLNTSTPNLPDFKEELYQWFKNQSS- >UniRef50_A3EXG6(34-1160:1274) Spike protein S2 n=4 Tax=Rousettus bat coronavirus HKU9 RepID=SPIKE_BCHK9 E=0 s/c=0.84 id=34% cov=94% ----------------------VLLPDPYIAYSGQTLRQNLFMADMSNTILYPVTPPAnganggfiYNTSIIPVSAGLFVNTwmYRQPASSRaycqepfG VAFGDTFENDRIAILIMapdnlgswsavapRNQTNIYLLVCsNATLCINPG----FNRWGPAGSFIAPDALVDHSNSCF--VNNTFSVNISTSRISL--- -AFLFKDGDLLIYHSGWLPTSNFEHGFSRGSHPMTYFMSLPVGGNLPRAQFFQSIVRSNAidkgdgmcTNFDVNLHVAHLINRDLLVSYFNNGSVANAAD CADSAAEELYCVTGSFDPPTGVYPLSRYRAQ-VAGFVRVTQRGSYCtPPYSVLQDP--PQPVVWRRYMLYDCVFDFTVVVDSLPTHQLQCYGVSPRRLAS MCYGSVTLDVMRINETHLNNLFNRVPDTFSLYNYALPDNFYGCLHAFYLNSTAPYAVANRF-----PIKPGGRQSNSAfIDTVINAAHYSP------FSY VYGLAVITLKPAAG------------------SKLVCPVANDTVVITDRCVQYNLYGYTGTGVLSKNTSLVIPDGkVFTASSTGTIIGV--SINSTTYSI MPCVTVPVSVGYHPNF---ERALLFNGLSCSqrsravtepvsvlWSASATAQDAFDTPSGCVVNVELRNTTIvnTCAMPIGNSLCfinGSIATANADSLP RLQLV-NYDPLYDNSTatpmtpvywVKVPTNFTLSATEEYIQTTAPKITIDCARYLCGDSSRCLNVLLHYGTFCNDINKALSRVSTILDSALLSLVKELS INTRdeVTTFSFDGDYNFTGLMgclgPNCGATTYRSAFSDLLYDKVRITDPGFMQSYQKCIDsqwGGSIRDLLCTQTYNGIAVLPPIVSPAMQALYTSLL VGAVASSGYTFGITSAGVIPFATQLQFRLNGIGVTTQVLVENQKLIASSFNNALVNIQKGFTETSIALSKMQDVINQHAAQLHTLVVQLGNSFGAISSSI NEIFSRLEGLAANAEVDRLINGRMMVLNTYVTQLLIQASEAKAQNALAAQKISECVKAQSLRNDFCGNGTHVLSIPQLAPNGVLFIHYAYTPTEYAFVQT SAGLCHNGTGYAPRQGMFVlpNNTNMWHFTTMQFYNPVNISASNTQVLTSCSVNYTSVNYTVLEPSVPGDYDFQKEFDKFYKNLST- >UniRef50_P05135(208-1040:1163) Spike protein S2 n=1237 Tax=Avian coronavirus RepID=SPIKE_IBV6 E=0 s/c=0.92 id=28% cov=72% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- -----------------------------------------------LAYFVNGTAQDVILCDGSPTGLLACQYNTGNFSDGFYPFTNSSLVKEKFIVYR ESSVN--------------TTLELTNFTFSN-VSNATPNTGGVQTIQLYQTITAQSGYYNLNFSFLSSFIYKASDYMYGSYHPSCKFRLETINNGLWFNS LSVSLGYGPIQGGCKQSVFANRATCCYAYSYNGP-----SLCKGVYRGELTKSFECGLLVFVTKTDG-----------------SRIQTRNEPFTLTQHN YNNITLDRCVEYNIYGRVGQGFITNVTNYAINYNYLadggmaILDTSGAIDIFvvQGEYGLNYYKVNPCEDVNQQfvvsggklvgILTSRNETGSQPlen QFYIKIINGTRRSRRSIT-------GNVTNCPYVTYGKFCIKPDGS---ISTIVPKELEHFVAPL------LNVTENVLIPDSFNLTVTDEYIQTRMDKV QINCLQYVCGNSLECRKLFQQYGPVCDNILSVVNSVGQKEDMELLYFYSSTKPSGFNTPVlsnVSTGEFNISLLLTPPSSASGRSFIEDLLFTSVESVGL PTDDAYKKCTAGPLgfLKDLACAREYNGLLVLPPIITAEMQTLYTSSLVASMAFGGITSAGA----IPFATQLQARINHLGITQSLLFKNQEKIAASFNK AIGHMQEGFRSTSLALQQIQDVVNKQSSILTETMASLNKNFGAISSVLQDIYQQLDSIQADAQVDRIITGRLSSLSVLASAKQAEYYRVSQQRELATQKI NECVKSQSIRYSFCGNGRHVLTIPQNAPNGIVFIHFTYTPESFVNVTAIVGFCVNpanasQYAIVPANgrGIFIQVNGSYYITARDMYMPRDITAGDIVT LTSCQANYVSVNKTVITTfVDNDDFDFDDELSKWWND---- >UniRef50_B3FHU5(203-1066:1226) Spike n=17 Tax=Coronavirinae RepID=B3FHU5_CVTKE E=0 s/c=0.81 id=30% cov=70% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- ------------------------------------------------------------------INKLRCAYQQFNFSTGFYDIDTFVPVTSNITYlP YPDLKDntgqeVCDFYVALKGDHV--------------IYNQSCVDSKYPFFKLKCNNTYSWDNDKLC---ILGSEIYVPGYNVY------TNTQHSYAG TIPNYPTCSSKGLSLENIYNNIGFNRFCVTKLLTT-------RDISS------------ITQYTCVYVVSVEGFDSyNQGIVYSY----VGVNFDFGTAM YSVKTAPMQFIYTEQCHKYNIYNIRGVGQILNVTgkdNTTLVDGGLVITSGSGLLAFRN--NGSLFSVQPCRT----VSTQAVIVNGSFVGLFVPASCwL ADQFNLGNHTEYVDGGCLISNKTISRKRRSTNAVYTGECTGLFAAMGtscIYSNGTVLNRTLPQPSVQTsvqpllgvvaNVSIPKELTLAVTTEYLQTRY QKVTIDCAKYVCGDSTRCRTLLQQYGSFCQSVNAILSGVNENEDNGLLQYAEAINTGYTLNftgyNVSNLGGFDLSLVLPKNltlAQNQGRSTIEDLLFD KVVTLGVSEVDQnYDKCIASrggsfTNLADLTCAQFYNGVMVLPGVVDPGLMAVYTGSLIGGMALGGITAAA----SIPFATQIQARVNYLALTQSVLLD NQNLIANSFNKALKGIQSALDTVSQgfvevargfesvtvALNKVQDVVNTHSDILNKLMAQLSVNFGAVSSSLNEIYLKLDQINADAQVDRLITGRLTAL STYVASLQLAAYKADQSRRLALQKVEECVKSQSMRYGFCGNGSHVLTIPQSAPNGIFFIHYTYQPTSYVTIEAVPGLCVTtpsgKYGVMPKtgSGIIFRQ NDTFFVTSTQLYEPKLLSYSEVVNLTSCEANYYNVSESE-TPFQPALPNFDDEFNDIF------ >UniRef50_A8JP00(24-1017:1128) Spike glycoprotein n=3 Tax=Rhinolophus bat coronavirus HKU2 RepID=A8JP00_9ALPC E=0 s/c=0.70 id=29% cov=69% ---------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------- --------------------------------------------------DQSGAVTRYSYCADGFVNGLQCKLRLFDIPPGVY--SNSEVEYPVALYTV VHNMSVCPqrPESYCGSNYCP----FKRVVFSNCVVNYTSWTSGLLRD---------------------YQHLVLPNGKFNPFTECNG-----LNRIVDD CVTGFVLRVGRGT----------AVNRTVITPYLKPNE----------------------------------CFGWSWNDYQDSIYDWWIadfVSTGAFV CEKNPDAP-RTGVCITYTIEKVTFQGVLYESNFTFAQYYNVLY-FGSQLKYVR--ILGKVYEVAPCFEASYDVLF---RSSSSFGLLYRSFDCNQlrisa sRFAERLlpsHNGTATALGCLFNATYAPNDtmVNCTNPLGDGFCADLLSNVVVRRMTFEKHDTTYVAPVTIErfTELPLDHQLVLTEQFLQTTMPKFSIS CETYICDVSKACKNLLFRYGGFCQKIEADIRGAGVLLDSDVSGLYSTIaaKTSSIMPTTDRFnvSQFFLPKVQSTSERFESRSVIEDLLFSKIETTGPGF YGDYYNCKKN-AIQDLTCAQYHNGILVIPPVMDAETLGMY-GGIAAASLTLGI--FGGQAGITTWSLAMAGRLNALGVVQNALVDDVNKLANGFNQLTAS VSKLALTTSSALQAIQAVVNQNAAQVESLVSGITENFGAISTNFKVISQRLDKLEADVQMDRLINGRMNVLQLFVTNYKLKIAELRNTHRYVQSLINECV YAQSLRNGFCGQGLHVLSLMQNAPSGIMFFHYSLIPNNTIIVKTTPGLCESDelgsKCIVAKDGVLVSANLSyWQWSPRNLYKPENLTFANVIAVSRG-A NYTTLNRTFDIPELNNTFPIEEEFREYFQNMSS- # NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665 HMM A C D E F G H I K L M N P Q R S T V W Y M->M M->I M->D I->M I->I D->M D->D Neff Neff_I Neff_D 0 * * 0 * 0 * * * * Q 1 * * * * * * * * * * * * * 0 * * * * * * 1 0 * * * * * * 1000 0 0 C 2 * 0 * * * * * * * * * * * * * * * * * * 2 0 * * * * * * 1000 0 0 V 3 * * * * * * * * * * * * * * * * * 0 * * 3 0 * * * * * * 1000 0 0 N 4 * * * * * * * * * * * 0 * * * * * * * * 4 0 * * * * * * 1000 0 0 L 5 * * * * * * * * * 0 * * * * * * * * * * 5 0 * * * * * * 1000 0 0 T 6 * * * * * * * * * * * * * * * * 0 * * * 6 0 * * * * * * 1000 0 0 T 7 * * * * * * * * * * * * * * * * 0 * * * 7 0 * * * * * * 1000 0 0 R 8 * * * * * * * * * * * * * * 0 * * * * * 8 0 * * * * * * 1000 0 0 T 9 * * * * * * * * * * * * * * * * 0 * * * 9 0 * * * * * * 1000 0 0 Q 10 * * * * * * * * * * * * * 0 * * * * * * 10 0 * * * * * * 1000 0 0 L 11 * * * * * * * * * 0 * * * * * * * * * * 11 0 * * * * * * 1000 0 0 P 12 * * * * * * * * * * * * 0 * * * * * * * 12 0 * * * * * * 1000 0 0 P 13 * * * * * * * * * * * * 0 * * * * * * * 13 0 * * * * * * 1169 0 0 A 14 993 * * * * * * * * * * 1007 * * * * * * * * 14 0 * * * * * * 1169 0 0 Y 15 * * * * * * * * * * * * * * * * * * * 0 15 0 * * * * * * 2076 0 0 T 16 * * * * * * * * * * * * * * * * 458 1879 * * 16 0 * * * * * * 2076 0 0 N 17 * * * * * * * * * * * 2106 * 381 * * * * * * 17 383 2100 * 1000 1000 * * 2076 1000 0 S 18 * * * * 1879 * * * * * * * * * * 1103 1930 * * * 18 0 * * * * * * 2076 0 0 F 19 * * 1930 * 2106 * * * * * * * * * * 2100 * 1879 * * 19 0 * * * * * * 2076 0 0 T 20 * * * * * * * * * * 2100 1879 * * * * 1015 * * * 20 0 * * * * * * 2076 0 0 R 21 * * * * * * * * 904 * * * * * 1103 * * * * * 21 0 * * * * * * 2076 0 0 G 22 * * * * * 1103 * * * * * * * * * * 904 * * * 22 0 * * * * * * 2076 0 0 V 23 * * * * * * * * * * * * * * * * 2226 787 * 2273 23 0 * * * * * * 2428 0 0 Y 24 * * * * * * * * * 2631 * * * * * * * * * 254 24 0 * * * * * * 2834 0 0 Y 25 * * * * * * * 2660 * 2631 * * * * * * * * * 556 25 250 * 2651 * * * * 2834 0 0 P 26 * * * * * * * * * * * * 0 * * * * * * * 26 542 1676 * 1000 1000 * 0 2600 1284 1000 D 27 * * 1058 * * 1676 * * * * * 2276 * * * * * * * * 27 0 * * * * * 0 2600 0 1000 K 28 2668 * * 2757 * * * * 2787 * * * 2414 * * 1465 * * * * 28 0 * * * * 0 * 2600 0 1000 V 29 * * * * * * * 2973 * * * 2905 * * * * 1763 3003 2660 2631 29 0 * * * * * * 2834 0 0 F 30 * * 2660 * 1368 * * 2631 * * * * * * * * * * * 1772 30 0 * * * * * * 2834 0 0 R 31 2631 * * * * * * * * * * 2651 * * 558 * * * * * 31 0 * * * * * * 2834 0 0 S 32 * * * * * * * * * * * 1224 * * * 1988 * 2660 * 2631 32 0 * * * * * * 2834 0 0 S 33 * * 2973 * * * * * * 2905 2885 * * * * 1170 2651 * * * 33 0 * * * * * * 2834 0 0 V 34 1895 * * * * 1641 * 2660 * * * * * * * * 2973 3003 * * 34 0 * * * * * * 2834 0 0 L 35 * * * * * 2651 * * * 940 * * * 2631 2660 * * * * * 35 249 2660 * 2585 263 * * 2834 1000 0 H 36 * 2660 * * * * 3003 * 2885 * * * * * * * 1139 * * 2973 36 0 * * * * * * 2834 0 0 S 37 * * * * * 1224 * * * 1792 * * * * * 1821 * * * * 37 0 * * * * * * 2834 0 0 T 38 * * * * * * * * * * * * * * 2631 2660 940 2651 * * 38 0 * * * * * * 2834 0 0 Q 39 * * * * * * * * * * * 1772 * 806 2885 * * * * * 39 0 * * * * * * 2834 0 0 D 40 * * 1988 * * * * 2660 * 2885 * 2631 * 2651 * * 2905 * * * 40 0 * * * * * * 2834 0 0 L 41 * * * * * * * * * 249 * * * * * * * 2660 * * 41 210 * 2885 * * * * 2834 0 0 F 42 * * * * 1098 * * * * * * * * 2500 * 2462 2520 * * * 42 0 * * * * * 0 2707 0 1000 L 43 * * * * * * * * 2520 635 2462 * * * * * * * * * 43 289 * 2462 * * * 0 2707 0 1000 P 44 1212 * * * * 2226 * * * * * * 1496 * * * * * * * 44 0 * * * * * 0 2428 0 1284 F 45 * * 2153 * 1496 * * 2273 * 2226 * * * * * * * * * * 45 0 * * * * * 0 2428 0 1284 F 46 * 2226 * * 2499 * * * * * 2153 * * * * * 2273 * * 2492 46 0 * * * * * 0 2428 0 1284 S 47 * * * 2226 * * * * * * * * * * * 787 * 2273 * * 47 0 * * * * 996 1004 2428 0 1284 N 48 * * 2499 * * * * * * * * 644 * * * 2448 * * * * 48 281 2499 * 2807 222 * 0 2715 1000 1000 V 49 * * * * * * * * * * * * * * * * 885 1125 * * 49 0 * * * * 0 * 2715 0 1000 T 50 * * * * * * * 2631 * 2885 * 2651 * * * * 878 * * * 50 0 * * * * * * 2834 0 0 W 51 * * * * * 2973 * * * 2631 * * * * * * 2660 2651 1345 * 51 0 * * * * * * 2834 0 0 F 52 * * * * 224 * * * * * * * * * * * * * * 2795 52 0 * * * * * * 3012 0 0 H 53 1939 * * * * * 2147 * 2047 * * * 2795 * * * 2974 * * * 53 0 * * * * * * 3012 0 0 A 54 3161 * * * * * * * * * * 2964 994 * * * 3133 2795 * * 54 400 * 2047 * * * * 3012 0 0 I 55 * * * * * 2619 * 1698 * * * * * * * * 1457 2600 * * 55 0 * * * * * 0 2628 0 1284 H 56 * * * * * * 2703 * * * * 1646 2357 * * * 2619 2566 * * 56 256 2619 * 3322 152 * 0 2628 1000 1284 K 57 * * * * * 1583 2693 * 2703 * * 2619 2357 * * * * * * * 57 0 * * * * * 0 2628 0 1284 R 58 2357 * * * * 1592 * * 2600 * * * * * 2703 * 2693 * * * 58 313 2357 * 3000 193 * 0 2628 1000 1284 F 59 * * * * 1698 * * 2600 * * * * * * * * * * * 924 59 0 * * * * * 0 2628 0 1284 D 60 * * 2703 * * 2693 * 2566 * * * 2357 1610 * * * * * * * 60 0 * * * * * 0 2628 0 1284 N 61 2619 * * * * 2600 * * * * * 1698 2566 * * * 2357 * * * 61 0 * * * * 0 * 2628 0 1284 P 62 * * 2974 * * * 1939 * * * * * 1096 * * 2795 * * * * 62 0 * * * * * * 3012 0 0 V 63 * * * * 1437 2914 * 1877 * * * * * * * * * 2147 * * 63 196 * 2974 * * * * 3012 0 0 L 64 * * * * 1654 * * 1800 * 1340 * * * * * * * * * * 64 210 2881 * 0 * 0 * 2862 1000 1000 P 65 * * * * * * * * * * * * 690 * * 1395 * * * * 65 412 2010 * 2515 277 * * 3012 1592 0 F 66 * * * * 224 * * * * * * * * * * * * 2795 * * 66 0 * * * * * * 3012 0 0 N 67 * * * * * * * * 3133 * * 431 * * * 2795 * * * * 67 0 * * * * * * 3012 0 0 D 68 2795 * 1096 * 2964 * * * * * * 1943 * * * * * * * * 68 434 * 1943 * * * * 3012 0 0 G 69 * * * * * 334 * * * * * * * * * 2276 * * * * 69 0 * * * * * 0 2600 0 1391 V 70 * * * * * * * 1117 * 2414 * 2276 * * * * * 2787 * * 70 247 * 2668 * * 0 * 2600 0 1391 Y 71 * * * * 1634 * * * * * * * * * * * * * 1235 1983 71 0 * * * * 0 * 2892 0 1000 F 72 3056 * * * 443 * * * * * * * * * * * * 2795 * * 72 185 3056 * 3585 126 * * 3012 1000 0 A 73 1096 * * * * * * * * 1969 2914 2795 * * * * * * * * 73 0 * * * * * * 3012 0 0 S 74 3133 * * * * * * * 3037 1969 * * * * 2914 3161 1920 * * * 74 224 2795 * 1000 1000 * * 3012 1000 0 T 75 * * * * * * * * * * * * * * * 2014 1039 3037 * 2795 75 0 * * * * * * 3012 0 0 E 76 * * 2974 2147 * * * * 3037 * * 1939 * * 2795 * * * * 3056 76 0 * * * * * * 3012 0 0 K 77 * * * * 3056 * * * 1502 * * 3037 * 2795 * 1939 * * * * 77 0 * * * * * * 3012 0 0 S 78 * * * * * * * * * * * * 1920 * * 443 * * * * 78 0 * * * * * * 3012 0 0 N 79 2795 * * * * * * * * * * 2147 * * 3037 * 976 * * * 79 0 * * * * * * 3012 0 0 I 80 * * * * 1974 * * 1037 * * * * * * * 2795 * 3133 * * 80 0 * * * * * * 3012 0 0 I 81 * * * * * * * 3161 * * * * * * * 1911 * 684 * * 81 0 * * * * * * 3012 0 0 R 82 * * 2964 * * * * 3056 3037 * * * * 2974 1435 2914 * * * * 82 224 2795 * 2807 222 * * 3012 1000 0 G 83 * * 3037 * * 187 * * * * * * * * * * * * * * 83 0 * * * * * * 3012 0 0 W 84 * * * * * 3037 * * * * * * * * 1365 3056 * 2795 2147 * 84 205 * 2914 * * * * 3012 0 0 I 85 2631 * * * * * * 1821 * 2905 * * * * * * * 1245 * * 85 0 * * * * 0 * 2834 0 1000 F 86 * * * * 683 * * 3037 * * * * * * * * * 1969 * * 86 425 * 1969 * * * * 3012 0 0 G 87 * * * * * 669 * * * * * * * * * * * 2221 * 2676 87 0 * * * * 0 * 2644 0 1432 T 88 * * 2795 * * * * * * * * 3056 * * * 1026 2032 * * * 88 0 * * * * * * 3012 0 0 T 89 * * * 2000 * * * * * * * 2914 * * * 2974 1029 * * * 89 185 * 3056 * * * * 3012 0 0 L 90 * * * * 1627 * * * * 2994 2972 * * 1241 * * * * * * 90 0 * * * * * 0 2900 0 1000 D 91 * * 2994 2640 * * * * * * * 2972 769 * * * * * * * 91 0 * * * * 0 * 2900 0 1000 S 92 3037 * * * * * * * * 2914 * 1954 * * * 2108 * 1969 * * 92 0 * * * * * * 3012 0 0 K 93 * * 2795 * * * * 3037 2147 1939 * * * * * * * * * 2014 93 0 * * * * * * 3012 0 0 T 94 * * * * * * * * * 2964 * * * * 2795 3133 1499 1943 * * 94 0 * * * * * * 3012 0 0 Q 95 * * * 2974 * * * 1911 * * 2964 2914 * 2147 * * * 3056 * * 95 0 * * * * * * 3012 0 0 S 96 2795 1365 * * * 3037 * * * * * * * * * 2147 * 3056 * * 96 0 * * * * * * 3012 0 0 L 97 * * * * * * * 2795 * 689 * * * * * 3037 * 3133 * * 97 0 * * * * * * 3012 0 0 L 98 * * * 3056 * * * 3133 * 1967 * * * * 2974 * 3037 * 1939 * 98 0 * * * * * * 3012 0 0 I 99 2964 * * * 3037 * * 1435 * * * * 1395 * * * * * * * 99 0 * * * * * * 3012 0 0 V 100 * * * * * * * 3133 * * 2795 * * * * * * 686 * 3056 100 224 2795 * 3700 115 * * 3012 1000 0 N 101 * * * * * * * * * * * 1096 1365 * 2795 * * * * * 101 0 * * * * * * 3012 0 0 N 102 * * * * * 2964 * * * * * 1029 * * * 1943 3037 * * * 102 198 * 2964 * * * * 3012 0 0 A 103 2991 * * * 2631 * * 2907 * * * * * 2626 * 1923 * * 2700 * 103 206 * 2907 * * * 0 2845 0 1000 T 104 * * * * * 2495 * * * * * * * * * 2556 1096 * * 2436 104 0 * * * * * 0 2729 0 1592 N 105 * * * * * * * * * * * 649 * * * 2436 * 2495 * * 105 269 2556 * 1000 1000 959 1042 2729 1000 1592 V 106 1665 * * * * * * 1213 * * * * * * * * * 1981 * * 106 0 * * * * 0 * 2845 0 1000 V 107 2914 * * * * * * 2974 * 2964 3056 * * * * * * 1525 * 2795 107 187 3037 * 4087 87 * * 3012 1000 0 I 108 3056 * * * * * * 1525 * 2795 2964 * * 2914 * * * 2974 * * 108 0 * * * * * * 3012 0 0 K 109 * * * * * * * * 3161 2795 * * * 2914 3133 1007 * * * * 109 0 * * * * * * 3012 0 0 V 110 3133 * * * 1943 * * * * * * * * * * * 2964 1006 * * 110 0 * * * * * * 3012 0 0 C 111 * 425 2974 * * * * * * * * 2964 * * * * * * * * 111 468 1853 * 1232 800 * * 3012 1625 0 E 112 * * * 3161 * * * * * * * 1376 * 1974 * 2964 3056 * * * 112 0 * * * * * * 3012 0 0 F 113 2795 * 2974 * 1039 * * * * * * * * * * * * * * 2047 113 0 * * * * * * 3012 0 0 Q 114 * * * 3133 * * * * * * * * * 3161 * 2914 962 2964 * * 114 0 * * * * * * 3012 0 0 F 115 * * * * 2064 * * 3056 * 1954 3037 * * 2914 * * * * * 2964 115 0 * * * * * * 3012 0 0 C 116 * 198 * * 2964 * * * * * * * * * * * * * * * 116 434 1943 * 2913 206 * * 3012 1391 0 N 117 * * 3133 3037 * * * 2795 * * * 1000 * 3056 * * * * * * 117 0 * * * * * * 3012 0 0 D 118 * * 3161 * * 2964 * * * 2014 * 1356 * * * * * * * 3037 118 0 * * * * * * 3012 0 0 P 119 * * * * * * * * * * * 2974 709 * * * 1939 * * * 119 0 * * * * * * 3012 0 0 F 120 2964 * * * 1502 2795 3037 * * * * * * * * * * 2914 * 3056 120 446 * 1911 * * * * 3012 0 0 L 121 * * 2571 * 2699 * * * * 2720 * * 2604 * * 2607 2342 * * * 121 0 * * * * * 0 2635 0 1540 G 122 2699 * * * * 1662 * * * * * 2604 2342 * * * * 2571 * * 122 0 * * * * 997 1003 2635 0 1540 V 123 * 2817 * 2765 * * * 2721 2753 * * * * * * * 2807 1900 * * 123 210 * 2882 * * * 0 2775 0 1000 Y 124 * * * * * * * 2662 2668 * * * * 2632 2601 * * 2643 * 2334 124 0 * * * * 1059 944 2696 0 1548 Y 125 * 1889 * * 1194 * * * * * * * 2929 * * * * * * 2627 125 0 * * * * * 0 2951 0 1000 H 126 * * * * * * 1214 * * * * 814 * * * * * * * * 126 0 * * * * * 0 2951 0 1000 K 127 * * * * * 2864 * * 2627 2814 * * 1893 * 2661 * 2929 * * * 127 0 * * * * 0 * 2951 0 1000 N 128 * * * * * * * * * * * 704 * * * 3133 * * 2795 2964 128 0 * * * * * * 3012 0 0 N 129 1969 * * * 2914 1920 * * 3133 3037 * 3161 * * * * * * * * 129 0 * * * * * * 3012 0 0 K 130 * * * * * 3037 * * 3161 * * 3056 1954 * * * 1365 * * * 130 0 * * * * * * 3012 0 0 S 131 1307 * 2964 * * * * * * * 3133 3037 * * 3056 3161 * * * * 131 185 3056 * 2322 322 * * 3012 1000 0 W 132 * * 2974 * * 1954 3056 * * 2914 * * * 3037 * 2964 * * 3161 * 132 0 * * * * * * 3012 0 0 M 133 2964 * 2974 * * * * * * * 3161 * * * 3037 2795 2094 2914 * * 133 0 * * * * * * 3012 0 0 E 134 * * 3056 3161 1877 * * 3037 * * * * * 1419 * * * * * * 134 0 * * * * * * 3012 0 0 S 135 * * * 2000 * * * 1882 * * * * * * * 2032 3133 3056 * * 135 0 * * * * * * 3012 0 0 E 136 1877 * * 3161 * 2914 3133 2974 3056 3037 * * * * * * * * * * 136 0 * * * * * * 3012 0 0 F 137 * * * * 1574 * * * * 3132 3080 * 2122 * * * 3362 * 3254 * 137 0 * * * * * * 3154 0 0 R 138 * * 3005 * * 3080 3254 * 2995 * 3362 * 3249 * 2255 * 3120 * * * 138 0 * * * * * * 3154 0 0 V 139 2042 * * * 2126 * * 2305 * * * * * * * * * 2179 * 3254 139 0 * * * * * * 3154 0 0 Y 140 * 3249 3254 3120 3362 * * * * 3005 * * * * * 3132 3080 * * 2179 140 0 * * * * * * 3154 0 0 S 141 * * 2236 * 2995 * * * * 2189 * * * * * 3390 3254 2042 * * 141 0 * * * * * * 3154 0 0 S 142 * * 1495 * 3080 * * * * 3249 * 1615 * * * 3390 * * * * 142 0 * * * * * * 3154 0 0 A 143 2376 * * * 3132 * 3005 * 3249 2995 * * * * * 2100 * 3254 * * 143 0 * * * * * * 3154 0 0 N 144 * * * * 3362 * * 2995 * 3080 * 3390 * * 3249 3005 2126 3254 * * 144 0 * * * * * * 3154 0 0 N 145 3120 * 3132 * * * * * * * * 586 * * * 3254 * * * * 145 0 * * * * * * 3154 0 0 C 146 * 1242 * 2126 3249 * * * * * * * * * * 3005 3080 * * * 146 0 * * * * * * 3154 0 0 T 147 * 3005 * * * * * 3120 * 3254 * * * * 3132 * 885 * * * 147 0 * * * * * * 3154 0 0 F 148 * * * * 868 3080 * * * * * * * * * 3120 * 3132 * 3254 148 192 * 3005 * * * * 3154 0 0 E 149 * 2938 * 2167 2950 2920 * * * * * 3049 * * 1918 * * * * * 149 398 * 2052 * * * 0 2959 0 1000 Y 150 2605 * * * * * * * * * * * * * * * * 2572 * 583 150 319 * 2332 * * 533 1695 2598 0 1753 V 151 * * * * * 2836 * 1878 * * * 2838 * * * * * 1159 * * 151 0 * * * * * 0 2892 0 1542 S 152 * * * * * 2838 * * * 2787 * 1634 * * * 1347 * * * * 152 0 * * * * 1009 991 2892 0 1542 Q 153 2014 * 3133 2914 * 2964 * * * * * 2795 * 3161 3037 * * * * * 153 0 * * * * 0 * 3012 0 1000 P 154 3362 * * * * * * 3080 * * * 1534 2318 * * 3132 3005 * * * 154 176 * 3120 * * * * 3154 0 0 F 155 * * * * 1101 * * * * * * * * * * 2793 * 2880 3105 2864 155 0 * * * * * 0 3012 0 1000 L 156 * 2793 * * * * * * * 2174 * * * * * 2030 1981 2880 * * 156 0 * * * * * 0 3012 0 1000 M 157 * * * * * * * 2864 * 2042 3246 * * * * * * 2858 * 1409 157 178 * 3105 * * * 0 3012 0 1000 D 158 * * 1352 * * * * * * 2771 * 1694 * * * * 2711 * * * 158 0 * * * * 1019 981 2916 0 1574 L 159 * * 2970 2857 * * * 2873 * 3244 * * * * * * * 1022 * * 159 0 * * * * * 0 3067 0 1000 E 160 * * 2857 3244 * * * * * * * 2850 * * * 1451 1989 * * * 160 0 * * * * * 0 3067 0 1000 G 161 2850 * 3007 2028 * 2136 * * * * * * * * * * 2873 2970 * * 161 0 * * * * * 0 3067 0 1000 K 162 * * 2850 * * * * * 2233 3035 * 2857 3007 * * 1921 * * * * 162 0 * * * * * 0 3067 0 1000 Q 163 2857 * * 2970 * * * * * * * * * 2136 2873 3222 3007 * * 2850 163 0 * * * * * 0 3067 0 1000 G 164 * * * 2857 * 2233 * 1938 * 2850 * * * * * 2970 * * * 3035 164 0 * * * * * 0 3067 0 1000 N 165 * * * * * 3007 * * 3035 * * 2233 * * * 1921 * * 2857 2850 165 0 * * * * * 0 3067 0 1000 F 166 * * * * 212 * * * * 2873 * * * * * * * * * * 166 212 * 2873 * * * 0 3067 0 1000 K 167 * * * * * 2635 2617 * 2006 * * 2810 * * * 2835 * * * 2793 167 0 * * * * * 0 2855 0 1527 N 168 * 2835 * * 2617 * 2998 2635 * * * 3015 * * * 2793 2810 * * * 168 0 * * * * * 0 2855 0 1527 L 169 * * * * * * * * * 2006 * * * * * * 1172 * * 1702 169 218 2835 * 3000 193 * 0 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