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Job DescriptionSwiss-Prot_entry_P0DV45_from_UniProt
Confidence100.00%DateWed Nov 27 10:14:46 GMT 2024
Rank89Aligned Residues232
% Identity22%Templatec8g6iA_
PDB info PDB header: blood clottingChain: A: PDB Molecule: PDBTitle: coagulation factor viii bound to a patient-derived anti-c1 domain2 antibody inhibitor
PDB Entry: PDBe RCSB PDBj
Resolution4.23 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   72.......80.........90.........100.........110......... 120.....
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Query Sequence  VPGPVIKVREGTKVKILFRNKLTVPASIHPHGVKYTTANVGVNIAGNP. . . . . . ASIVAP
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Template Conservation    

      
        
           
                            
Template Sequence  LLGPTIQAEVYDTVVVTLKNMASHPVSLHAVGVSFWKSSEGAEYEDHTSQREKEDDKVLP
Template Known Secondary structure  T




TT

SSS





SS



STT




TT

S
SSTTTT


S
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   126...130.........140 .........150.........160.........170. ..
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Query Sequence  GDSRIFEWDTAGTPG. . . . . . . . . TWFYHSYVFERGGEEGLSRGLWGALIVEPVG. . . GD
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Template Conservation                                  ...        
  
             
Template Sequence  GKSQTYVWQVLKENGPTASDPPCLTYSYLSHV. . . DLVKDLNSGLIGALLVCREGSLTRE
Template Known Secondary structure  S







TTTS

SSS
S





S...
S





SSSS
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   174.....180.........190.........200.........210......... 220.........230..
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Query Sequence  PNPPDKEFVVFMHAFNVNGQEYYAFNNKSGDIELMRGDSSAFPGET. WKAKMGDKVRFHL
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Template Conservation                          ...          

                     
Template Sequence  RTQNLHEFVLLFAVFDEGKSWHSA. . . ARAQPAMHTVNGYVNRSLPGLIGCHKKSVYWHV
Template Known Secondary structure 
TTS
SS

B



TTSSS

...SS



BTTB
TT





SSB




B
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   233.... ..240.........250.........260.........270.........280.........290
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Query Sequence  INITE. . EAHTFHTHGHRWLDKSCDKLIDTIGLNPFDSYVLDFVAGEGVGKGNWAFHCQS
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Template Sequence  IGMGTSPEVHSIFLEGHTFLVRH. . HRQASLEISPLTFLTAQTFLMD. . . LGQFLLFCHI
Template Known Secondary structure 


SSS






S



BTT..B







SS





B
S...
S





S
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   291........300.........310....
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Query Sequence  QEHMMNGMFGIFMVEEGKRVNAVI
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Template Conservation                          
Template Sequence  SSHHHGGMEAHVRVESCAEKHPKT
Template Known Secondary structure  S
TTTT







SSS




Template Predicted Secondary structure 















Download:Text version FASTA version

No model constructed - rank, confidence too low


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Please cite: The Phyre2 web portal for protein modeling, prediction and analysis
Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]
 
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