Job Description Undefined Confidence 99.96% Date Thu Nov 13 08:26:15 GMT 2025 Rank 251 Aligned Residues 279 % Identity 13% Template c8xizA_ PDB info PDB header: hydrolase Chain: A: PDB Molecule: Microsomal epoxide hyddrolase PDBTitle: crystal structure of an epoxide hydrolase mutant a250ic/l344v from aspergillus usamii e001 at 2.17 angstroms resolution PDB Entry: PDBe RCSB PDBj Resolution UNK

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

31

.

.

.

.

.

.

.

.

40

.

.

.

.

.

.

.

.

.

50

.

.

.

.

.

.

.

.

.

60

.

.

.

.

.

.

.

.

.

70

.

.

.

.

.

.

.

.

.

80

.

Predicted Secondary structure

.

.

.

.

.

.

.

.

.

Query Sequence

H

Y

R

V

E

Q

V

G

D

V

K

V

F

Y

R

E

A

.

.

G

D

P

A

A

P

A

V

L

L

L

H

G

F

A

A

S

S

Y

M

W

R

D

V

I

E

A

L

A

D

G

Y

.

.

.

.

.

.

.

H

V

Query Conservation

.

.

.

.

.

.

.

.

.

Alig confidence

.

.

.

.

.

.

.

.

.

Template Conservation

Template Sequence

P

Q

F

T

Y

D

I

E

G

L

T

I

H

F

V

A

L

F

S

E

K

K

D

A

I

P

I

V

L

L

H

G

W

P

G

S

F

L

E

F

L

P

V

L

T

S

I

R

D

K

Y

S

P

E

T

L

P

Y

H

I

Template Known Secondary structure

T

T

S

T

T

.

T

T

G

G

G

G

T

T

T

Template Predicted Secondary structure

82

.

.

.

.

.

.

.

90

.

.

.

.

.

.

.

.

.

100

.

.

.

.

.

.

.

.

.

110

.

.

.

.

.

.

.

.

.

120

.

.

.

.

.

.

.

.

.

130

.

.

.

.

.

.

.

.

.

140

Predicted Secondary structure

.

Query Sequence

I

A

P

D

L

P

A

F

G

Y

T

E

A

P

A

R

G

Q

Y

D

Y

T

F

A

N

L

T

K

T

I

E

R

F

T

D

Q

L

K

L

T

R

.

Y

A

M

A

V

H

D

Y

G

A

P

V

G

W

R

L

A

L

Query Conservation

.

Alig confidence

.

.

Template Conservation

.

Template Sequence

V

V

P

S

L

P

G

Y

T

F

S

S

G

P

P

L

D

V

N

.

F

N

G

E

D

T

A

R

V

I

N

K

V

M

L

N

L

G

F

E

D

G

Y

V

A

Q

G

G

D

I

G

S

K

I

G

R

I

L

A

V

Template Known Secondary structure

.

.

T

T

S

T

T

S

S

S

S

.

T

T

T

T

T

Template Predicted Secondary structure

.

141

.

.

.

.

.

.

.

.

150

.

.

.

.

.

.

.

.

.

160

.

.

.

.

.

.

.

.

.

170

.

.

.

.

.

.

.

.

.

180

.

.

.

.

.

.

Predicted Secondary structure

.

.

.

.

.

.

.

.

.

.

.

.

.

.

Query Sequence

A

H

P

S

R

I

T

A

I

I

S

Q

N

G

N

A

Y

E

E

G

L

S

A

G

W

E

P

I

R

K

Y

W

N

D

P

T

A

E

N

R

Q

A

.

.

.

.

.

.

.

.

.

.

.

.

.

.

L

S

D

F

Query Conservation

.

.

.

.

.

.

.

.

.

.

.

.

.

.

Alig confidence

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

Template Conservation

.

Template Sequence

D

H

D

.

A

C

K

A

V

H

L

N

A

C

Y

M

G

K

P

S

S

I

I

T

E

E

D

K

R

A

L

A

R

A

Q

W

F

A

T

F

G

S

G

Y

I

V

E

H

G

T

R

P

S

T

I

G

N

A

L

S

Template Known Secondary structure

T

.

T

S

S

T

T

S

S

Template Predicted Secondary structure

.

187

.

.

190

.

.

.

.

.

.

.

.

.

200

.

.

.

.

.

.

.

.

.

210

.

.

.

.

.

.

.

.

.

220

.

.

.

.

.

.

.

.

.

230

.

.

.

.

.

.

.

.

.

240

.

.

.

.

Predicted Secondary structure

.

.

Query Sequence

P

T

P

A

S

I

K

W

Q

Y

V

E

G

V

S

D

T

S

L

.

.

V

A

P

D

A

Y

T

L

E

G

A

Q

I

L

R

P

G

M

A

D

I

Q

L

D

L

L

L

D

Y

A

T

N

V

E

Q

Y

P

A

F

Query Conservation

.

.

Alig confidence

.

.

Template Conservation

Template Sequence

T

S

P

V

A

L

L

S

W

I

G

E

K

F

L

D

W

A

G

E

T

I

P

L

E

T

I

L

E

S

V

T

L

Y

W

F

T

E

T

F

P

R

S

I

Y

H

Y

R

E

N

F

P

P

P

K

L

R

H

T

E

Template Known Secondary structure

S

S

S

.

.

.

T

T

S

G

G

G

G

G

G

S

S

.

.

S

S

G

G

G

Template Predicted Secondary structure

245

.

.

.

.

250

.

.

.

.

.

.

.

.

.

260

.

.

.

.

.

.

.

.

.

270

.

.

.

.

.

.

.

.

.

280

.

.

.

.

.

.

.

.

.

290

.

.

.

.

.

.

.

.

.

300

.

.

.

Predicted Secondary structure

.

Query Sequence

Q

A

Y

F

R

E

Y

Q

P

P

L

L

A

V

W

G

E

H

D

P

F

F

L

P

P

G

A

E

A

W

K

R

D

I

P

D

A

D

I

.

R

L

Y

D

T

G

H

F

A

L

E

T

H

S

E

V

I

I

P

T

Query Conservation

.

Alig confidence

.

.

.

.

Template Conservation

.

.

.

Template Sequence

.

D

P

R

W

Y

I

R

K

P

F

G

F

S

Y

Y

P

M

E

V

V

P

T

P

R

A

W

V

E

.

.

T

T

G

N

L

V

F

W

Q

A

H

E

K

G

G

H

F

A

A

L

E

R

P

Q

D

Y

L

D

D

Template Known Secondary structure

.

G

G

G

T

B

S

S

S

.

.

T

T

S

S

B

S

S

Template Predicted Secondary structure

.

.

.

304

.

.

.

.

.

310

.

.

.

.

Predicted Secondary structure

Query Sequence

I

R

Q

F

L

D

D

H

V

S

L

Query Conservation

Alig confidence

Template Conservation

Template Sequence

L

T

A

F

C

E

Q

V

W

A

G

Template Known Secondary structure

Template Predicted Secondary structure

No model constructed - rank, confidence too low

---

Phyre is now FREE for commercial users!

All images and data generated by Phyre2 are free to use in any publication with acknowledgement

Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
© Structural Bioinformatics Group, Imperial College, London Michael Sternberg   Disclaimer Terms and Conditions		Phyre2 is part of Genome3D