Job Description Undefined Confidence 99.87% Date Thu Nov 13 08:26:15 GMT 2025 Rank 453 Aligned Residues 242 % Identity 11% Template c8b9sA_ PDB info PDB header: hydrolase Chain: A: PDB Molecule: Prolyl oligopeptidase family protein PDBTitle: native form, thermostable lipase from thermoanaerobacter thermohydrosulfuricus PDB Entry: PDBe RCSB PDBj Resolution UNK

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.					50	.	.	.	.	.	.	.	.	.	60	.	.	.	.					.	.	.	.	.	70	.	.	.	.	.	.	.		.	.	80
Predicted Secondary structure																						.	.	.	.																.	.	.	.														.
Query Sequence		V	H	Y	R	V	E	Q	V	G	D	V	K	V	F	Y	R	E	A	G	D	.	.	.	.	P	A	A	P	A	V	L	L	L	H	G	F	A	A	S	.	.	.	.	S	Y	M	W	R	D	V	I	E	A	L	A	D	.	G	Y	H
Query Conservation																						.	.	.	.																.	.	.	.														.
Alig confidence																						.	.	.	.																.	.	.	.														.
Template Conservation
Template Sequence		Q	K	A	V	E	I	T	Y	N	G	K	T	L	R	G	M	M	H	L	P	D	D	V	K	G	K	V	P	M	V	I	M	F	H	G	F	T	G	N	K	V	E	S	H	F	I	F	V	K	M	S	R	A	L	E	K	V	G	I	G
Template Known Secondary structure										T	T											S	S			S											T	T			T	T		G	G	G											T	T	T
Template Predicted Secondary structure
		81	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.				.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.
Predicted Secondary structure																																								.	.	.
Query Sequence		V	I	A	P	D	L	P	A	F	G	Y	T	E	A	P	A	R	G	Q	Y	D	Y	T	F	A	N	L	T	K	T	I	E	R	F	T	D	Q	L	.	.	.	K	L	T	R	Y	A	M	A	V	H	D	Y	G	A	P	V	G	W	R
Query Conservation																																								.	.	.
Alig confidence																																								.	.	.
Template Conservation
Template Sequence		S	V	R	F	D	F	Y	G	S	G	E	S	D	G	D	F	S	E	M	T	F	S	S	E	L	E	D	A	R	Q	I	L	K	F	V	K	E	Q	P	T	T	D	P	E	R	I	G	L	L	G	L	S	M	G	G	A	I	A	G	I
Template Known Secondary structure						.	.	T	T	S	T	T	S	S	S		G	G	G																				S	T	T												T
Template Predicted Secondary structure
		138	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.
Predicted Secondary structure
Query Sequence		L	A	L	A	H	P	S	R	I	T	A	I	I	S	Q	N	G	N	A	Y	E	E	G	L	S	A	G	W	E	P	I	R	K	Y	W	N	D	P	T	A	E	N	R	Q	A	L	S	D	F	P	T	P	A	S	I	K	W	Q	Y	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	A	R	E	Y	K	D	E	I	K	A	L	V	L	W	A	P	A	F	N	M	P	E	L	I	M	N	E	S	V	K	Q	Y	G	A	I	M	E	Q	L	G	F	V	D	I	G	G	H	K	L	S	K	D	F	V	E	D	I	S	K
Template Known Secondary structure						T	T	T	T								S			T	T								G	G	G	S										S				S	S	S												T	T
Template Predicted Secondary structure
		198	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.
Predicted Secondary structure
Query Sequence		E	G	V	S	D	T	S	L	V	A	P	D	A	Y	T	L	E	G	A	Q	I	L	R	P	G	M	A	D	I	Q	L	D	L	L	L	D	Y	A	T	N	V	E	Q	Y	P	A	F	Q	A	Y	F	R	E	Y	Q	P	P	L	L	A
Query Conservation
Alig confidence						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	N	I	F	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	L	S	K	G	Y	D	K	K	V	L	I
Template Known Secondary structure						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.				T	T			S
Template Predicted Secondary structure						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
		258	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.				280	.	.	.	.	.	.	.	.	.	290	.		.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.
Predicted Secondary structure																								.	.	.													.
Query Sequence		V	W	G	E	H	D	P	F	F	L	P	P	G	A	E	A	W	K	R	D	I	P	.	.	.	D	A	D	I	R	L	Y	D	T	G	H	F	.	A	L	E	T	H	S	E	V	I	I	P	T	I	R	Q	F	L	D	D	H	V	S
Query Conservation																								.	.	.													.
Alig confidence																								.	.	.													.
Template Conservation
Template Sequence		V	H	G	T	N	D	E	A	V	E	Y	K	V	S	D	R	I	L	K	E	V	Y	G	D	N	A	T	R	V	T	I	E	N	A	D	H	T	F	K	S	L	E	W	E	K	K	A	I	E	E	S	V	E	F	F	K	K	E	L	L
Template Known Secondary structure					T	T		S	S	S												T			T	T							T	T			T	T			S																				S
Template Predicted Secondary structure
		314	.
Predicted Secondary structure
Query Sequence		L	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	G
Template Known Secondary structure
Template Predicted Secondary structure

No model constructed - rank, confidence too low

---

Phyre is now FREE for commercial users!

All images and data generated by Phyre2 are free to use in any publication with acknowledgement

Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
© Structural Bioinformatics Group, Imperial College, London Michael Sternberg   Disclaimer Terms and Conditions		Phyre2 is part of Genome3D