Job Description Undefined Confidence 99.95% Date Thu Nov 13 08:26:15 GMT 2025 Rank 225 Aligned Residues 248 % Identity 15% Template c7wwfA_ PDB info PDB header: biosynthetic protein Chain: A: PDB Molecule: Esterase PDBTitle: crystal structure of bioh3 from mycolicibacterium smegmatis PDB Entry: PDBe RCSB PDBj Resolution UNK

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

50

.

.

.

.

.

.

.

.

.

60

.

.

.

.

.

.

.

.

.

70

.

.

.

.

.

.

.

.

.

80

.

.

.

.

.

.

.

.

.

90

.

.

.

.

.

Predicted Secondary structure

.

.

.

.

.

.

.

.

.

.

.

.

.

.

Query Sequence

P

A

A

P

A

V

L

L

L

H

G

F

A

A

S

S

Y

M

W

R

D

V

I

E

A

L

A

D

.

G

Y

H

V

I

A

P

D

L

P

A

F

G

Y

T

E

A

P

.

.

.

.

.

.

.

.

.

.

.

.

.

Query Conservation

.

.

.

.

.

.

.

.

.

.

.

.

.

.

Alig confidence

.

.

.

.

.

.

.

.

.

.

.

.

.

.

Template Conservation

Template Sequence

N

S

G

T

L

A

V

L

V

H

G

A

W

H

S

S

L

H

W

A

A

A

Q

R

G

L

A

R

R

G

V

A

S

I

A

V

D

L

P

G

H

G

L

D

A

P

V

P

S

G

Y

L

T

A

G

Q

P

G

L

E

Template Known Secondary structure

T

T

T

T

G

G

G

G

T

T

T

T

G

G

G

T

T

T

T

S

T

T

T

T

T

T

Template Predicted Secondary structure

96

.

.

.

100

.

.

.

.

.

.

.

.

.

110

.

.

.

.

.

.

.

.

.

120

.

.

.

.

.

.

.

.

.

130

.

.

.

.

.

.

.

.

.

140

.

.

.

.

.

.

.

.

.

150

.

Predicted Secondary structure

.

.

.

.

Query Sequence

.

.

A

R

G

Q

Y

D

Y

T

F

A

N

L

T

K

T

I

E

R

F

T

D

Q

L

K

.

.

L

T

R

Y

A

M

A

V

H

D

Y

G

A

P

V

G

W

R

L

A

L

A

H

P

S

R

I

T

A

I

I

S

Query Conservation

.

.

.

.

Alig confidence

.

.

.

.

.

Template Conservation

.

Template Sequence

T

E

K

S

A

L

A

D

I

T

.

D

D

L

A

D

A

V

V

D

A

L

A

E

V

R

S

R

F

A

R

V

L

L

V

A

H

S

A

G

G

G

P

A

S

L

A

A

E

K

A

P

E

L

V

D

H

L

V

Y

Template Known Secondary structure

T

.

.

.

T

T

T

T

.

S

G

G

G

S

G

G

G

G

G

G

S

Template Predicted Secondary structure

.

152

.

.

.

.

.

.

.

160

.

.

.

.

.

.

.

.

.

170

.

.

.

.

.

.

.

.

.

180

.

.

.

.

.

.

.

.

.

190

.

.

.

.

.

.

.

.

.

200

.

.

.

.

.

.

.

.

.

210

.

Predicted Secondary structure

Query Sequence

Q

N

G

N

A

Y

E

E

G

L

S

A

G

W

E

P

I

R

K

Y

W

N

D

P

T

A

E

N

R

Q

A

L

S

D

F

P

T

P

A

S

I

K

W

Q

Y

V

E

G

V

S

D

T

S

L

V

A

P

D

A

Y

Query Conservation

Alig confidence

.

.

.

.

.

.

Template Conservation

.

.

.

.

.

.

Template Sequence

L

A

A

F

V

P

A

A

R

P

R

F

T

D

Y

I

N

A

P

E

N

A

D

V

V

A

L

.

.

.

.

.

.

P

I

F

S

D

P

A

N

L

G

A

H

R

L

N

P

L

S

S

D

A

I

E

V

D

A

I

Template Known Secondary structure

S

S

S

S

S

T

T

S

G

G

G

T

T

S

.

.

.

.

.

.

.

.

.

.

.

S

T

T

T

S

Template Predicted Secondary structure

.

.

.

.

.

.

212

.

.

.

.

.

.

.

220

.

.

.

.

.

.

.

.

.

230

.

.

.

.

.

.

.

.

.

240

.

.

.

.

.

.

.

.

.

250

.

.

.

.

.

.

.

.

.

260

.

.

.

.

.

.

.

.

.

270

Predicted Secondary structure

.

Query Sequence

T

L

E

G

A

Q

I

L

R

P

G

M

A

D

I

Q

L

D

L

L

L

D

Y

A

T

N

V

E

Q

Y

P

A

F

Q

A

Y

F

R

E

Y

.

Q

P

P

L

L

A

V

W

G

E

H

D

P

F

F

L

P

P

G

Query Conservation

.

Alig confidence

.

.

Template Conservation

.

Template Sequence

R

R

A

F

L

T

D

P

P

D

.

A

P

E

G

W

R

H

L

L

H

P

D

E

P

Y

A

S

L

S

A

P

V

P

V

T

P

R

R

W

G

R

I

P

R

T

Y

I

R

L

D

G

D

R

A

L

A

P

T

T

Template Known Secondary structure

S

T

T

.

T

S

S

S

T

T

T

G

G

G

S

T

T

S

S

S

Template Predicted Secondary structure

.

271

.

.

.

.

.

.

.

.

280

.

.

.

.

.

.

.

.

.

290

.

.

.

.

.

.

.

.

.

300

.

.

.

.

.

.

.

Predicted Secondary structure

.

.

.

.

.

.

Query Sequence

A

E

A

W

K

R

D

I

.

.

.

.

P

D

A

D

I

.

R

L

Y

.

D

T

G

H

F

A

L

E

T

H

S

E

V

I

I

P

T

I

R

Q

F

Query Conservation

.

.

.

.

.

.

Alig confidence

.

.

.

.

.

.

.

.

Template Conservation

.

.

Template Sequence

Q

N

.

L

I

A

E

A

D

R

L

T

P

D

N

P

F

G

V

R

S

L

P

G

D

H

S

P

V

.

H

R

P

G

E

L

A

D

L

L

A

G

I

Template Known Secondary structure

.

S

T

T

S

.

.

S

S

S

.

S

T

Template Predicted Secondary structure

.

.

No model constructed - rank, confidence too low

---

Phyre is now FREE for commercial users!

All images and data generated by Phyre2 are free to use in any publication with acknowledgement

Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
© Structural Bioinformatics Group, Imperial College, London Michael Sternberg   Disclaimer Terms and Conditions		Phyre2 is part of Genome3D