Job Description Undefined Confidence 99.97% Date Thu Nov 13 08:26:15 GMT 2025 Rank 52 Aligned Residues 283 % Identity 19% Template c7omoA_ PDB info PDB header: luminescent protein Chain: A: PDB Molecule: Renilla reniformis luciferase RLuc8-D120A variant PDBTitle: crystal structure of coelenteramine-bound renilla reniformis luciferase rluc8-d120a variant PDB Entry: PDBe RCSB PDBj Resolution UNK

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

26

.

.

.

30

.

.

.

.

.

.

.

.

.

40

.

.

.

.

.

.

.

.

.

50

.

.

.

.

.

.

.

.

.

60

.

.

.

.

.

.

.

.

.

70

.

.

.

.

.

.

.

.

.

80

.

.

.

.

.

Predicted Secondary structure

Query Sequence

A

A

P

Q

V

H

Y

R

V

E

Q

V

G

D

V

K

V

F

Y

R

E

A

G

D

P

A

A

P

A

V

L

L

L

H

G

F

A

A

S

S

Y

M

W

R

D

V

I

E

A

L

A

D

G

Y

H

V

I

A

P

D

Query Conservation

Alig confidence

Template Conservation

Template Sequence

P

Q

W

W

A

R

C

K

Q

M

N

V

L

D

S

F

I

N

Y

Y

D

S

E

K

H

A

E

N

A

V

I

F

L

H

G

N

A

T

S

S

Y

L

W

R

H

V

V

P

H

I

E

P

V

A

R

C

I

I

P

D

Template Predicted Secondary structure

86

.

.

.

90

.

.

.

.

.

.

.

.

.

100

.

.

.

.

.

.

.

.

.

110

.

.

.

.

.

.

.

.

.

120

.

.

.

.

.

.

.

.

.

130

.

.

.

.

.

.

.

.

.

140

.

.

.

.

Predicted Secondary structure

.

Query Sequence

L

P

A

F

G

Y

T

E

A

P

A

R

G

Q

Y

D

Y

T

F

A

N

L

T

K

T

I

E

R

F

T

D

Q

L

K

L

.

T

R

Y

A

M

A

V

H

D

Y

G

A

P

V

G

W

R

L

A

L

A

H

P

S

Query Conservation

.

Alig confidence

.

.

.

Template Conservation

.

.

Template Sequence

L

I

G

M

G

K

S

G

K

S

G

.

.

N

G

S

Y

R

L

L

D

H

Y

K

Y

L

T

A

W

F

E

L

L

N

L

P

K

K

I

I

F

V

G

H

A

W

G

A

A

L

A

F

H

Y

A

Y

E

H

Q

D

Template Predicted Secondary structure

.

.

145

.

.

.

.

150

.

.

.

.

.

.

.

.

.

160

.

.

.

.

.

.

.

.

.

170

.

.

.

.

.

.

.

.

.

180

.

.

.

.

.

.

.

.

.

190

.

.

.

.

.

.

.

.

.

200

.

.

.

.

Predicted Secondary structure

Query Sequence

R

I

T

A

I

I

S

Q

N

G

N

A

Y

E

E

G

L

S

A

G

W

E

P

I

R

K

Y

W

N

D

P

T

A

E

N

R

Q

A

L

S

D

F

P

T

P

A

S

I

K

W

Q

Y

V

E

G

V

S

D

T

S

Query Conservation

Alig confidence

.

.

Template Conservation

.

.

Template Sequence

R

I

K

A

I

V

H

M

E

S

V

V

D

V

I

E

S

W

D

E

W

P

D

I

E

E

D

I

A

L

I

K

S

E

.

.

E

G

E

K

M

V

L

E

N

N

F

F

V

E

T

V

L

P

S

K

I

M

R

K

Template Predicted Secondary structure

.

.

205

.

.

.

.

210

.

.

.

.

.

.

.

.

.

220

.

.

.

.

.

.

.

.

.

230

.

.

.

.

.

.

.

.

.

240

.

.

.

.

.

.

.

.

.

250

.

.

.

.

.

.

Predicted Secondary structure

.

.

.

.

.

.

.

.

Query Sequence

L

V

A

P

D

A

Y

T

L

E

G

A

Q

I

L

R

P

G

M

A

D

I

Q

L

D

L

L

L

D

Y

A

T

N

V

E

Q

Y

P

A

F

Q

A

Y

F

R

E

Y

.

.

.

.

.

.

.

.

Q

P

P

L

L

Query Conservation

.

.

.

.

.

.

.

.

Alig confidence

.

.

.

.

.

.

.

.

Template Conservation

Template Sequence

L

E

P

E

E

F

A

A

Y

L

E

P

F

K

E

K

G

E

V

R

R

P

T

L

S

W

P

R

E

I

P

L

V

K

G

G

K

P

D

V

V

Q

I

V

R

N

Y

N

A

Y

L

R

A

S

D

D

L

P

K

L

Template Predicted Secondary structure

257

.

.

260

.

.

.

.

.

.

.

.

.

270

.

.

.

.

.

.

.

.

.

280

.

.

.

.

.

.

.

.

.

290

.

.

.

.

.

.

.

.

.

300

.

.

.

.

.

.

.

.

.

310

.

.

.

.

Predicted Secondary structure

Query Sequence

A

V

W

G

E

H

D

P

F

F

L

P

P

G

A

E

A

W

K

R

D

I

P

D

A

D

I

R

L

Y

D

T

G

H

F

A

L

E

T

H

S

E

V

I

I

P

T

I

R

Q

F

L

D

D

H

V

S

L

Query Conservation

Alig confidence

.

.

Template Conservation

.

.

Template Sequence

F

I

E

S

D

P

G

.

F

F

S

N

A

I

V

E

G

A

K

K

.

F

P

N

T

E

F

V

K

V

K

G

L

H

F

L

Q

E

D

A

P

D

E

M

G

K

Y

I

K

S

F

V

E

R

V

L

K

N

Template Predicted Secondary structure

.

.

No model constructed - rank, confidence too low

---

Phyre is now FREE for commercial users!

All images and data generated by Phyre2 are free to use in any publication with acknowledgement

Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
© Structural Bioinformatics Group, Imperial College, London Michael Sternberg   Disclaimer Terms and Conditions		Phyre2 is part of Genome3D