Job Description Undefined Confidence 99.68% Date Thu Nov 13 08:26:15 GMT 2025 Rank 391 Aligned Residues 230 % Identity 13% Template c6y0fC_ PDB info PDB header: hydrolase Chain: C: PDB Molecule: Prolyl endopeptidase FAP PDBTitle: structure of human fapalpha in complex with linagliptin PDB Entry: PDBe RCSB PDBj Resolution UNK

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		27	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.							.	.	.	.	.	.	.	.	60	.	.						.	.	.	.	.	.	.	70	.	.	.	.	.
Predicted Secondary structure																											.	.	.	.	.	.												.	.	.	.	.
Query Sequence		A	P	Q	V	H	Y	R	V	E	Q	V	G	D	V	K	V	F	Y	R	E	A	G	D	P	A	.	.	.	.	.	.	A	P	A	V	L	L	L	H	G	F	A	.	.	.	.	.	A	S	S	Y	M	W	R	D	V	I	E	A	L
Query Conservation																											.	.	.	.	.	.												.	.	.	.	.
Alig confidence																											.	.	.	.	.	.												.	.	.	.	.
Template Conservation
Template Sequence		L	P	K	E	E	I	K	K	L	E	V	D	E	I	T	L	W	Y	K	M	I	L	P	P	Q	F	D	R	S	K	K	Y	P	L	L	I	Q	V	Y	G	G	P	C	S	Q	S	V	R	S	V	F	A	V	N	W	I	S	Y	L	A
Template Predicted Secondary structure
		76	.		.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.						.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120			.	.	.	.	.	.	.
Predicted Secondary structure				.																			.	.	.	.	.																										.	.
Query Sequence		A	D	.	G	Y	H	V	I	A	P	D	L	P	A	F	G	Y	T	E	A	P	.	.	.	.	.	A	R	G	Q	Y	D	Y	T	F	A	N	L	T	K	T	I	E	R	F	T	D	Q	L	K	L	.	.	T	R	Y	A	M	A	V
Query Conservation				.																			.	.	.	.	.																										.	.
Alig confidence				.																			.	.	.	.	.																										.	.
Template Conservation
Template Sequence		S	K	E	G	M	V	I	A	L	V	D	G	R	G	T	A	F	Q	G	D	K	L	L	Y	A	V	Y	R	K	L	G	V	Y	E	V	E	D	Q	I	T	A	V	R	K	F	I	E	M	G	F	I	D	E	K	R	I	A	I	W	G
Template Predicted Secondary structure
		128	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.
Predicted Secondary structure
Query Sequence		H	D	Y	G	A	P	V	G	W	R	L	A	L	A	H	P	S	R	I	T	A	I	I	S	Q	N	G	N	A	Y	E	E	G	L	S	A	G	W	E	P	I	R	K	Y	W	N	D	P	T	A	E	N	R	Q	A	L	S	D	F	P
Query Conservation
Alig confidence																																																					.	.	.	.	.	.	.	.	.
Template Conservation																																																					.	.	.	.	.	.	.	.	.
Template Sequence		W	S	Y	G	G	Y	V	S	S	L	A	L	A	S	G	T	G	L	F	K	C	G	I	A	V	A	P	V	S	S	W	E	Y	Y	A	S	V	Y	T	E	R	F	M	G	L	P	T	K	D	D	N	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																					.	.	.	.	.	.	.	.	.
		188	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.
Predicted Secondary structure
Query Sequence		T	P	A	S	I	K	W	Q	Y	V	E	G	V	S	D	T	S	L	V	A	P	D	A	Y	T	L	E	G	A	Q	I	L	R	P	G	M	A	D	I	Q	L	D	L	L	L	D	Y	A	T	N	V	E	Q	Y	P	A	F	Q	A	Y
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	L	E	H	Y	K	N	S	T	V	M	A	R
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
		248	.	250	.	.		.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.					.	.		.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.
Predicted Secondary structure							.																														.	.	.	.			.
Query Sequence		F	R	E	Y	Q	.	P	P	L	L	A	V	W	G	E	H	D	P	F	F	L	P	P	G	A	E	A	W	K	R	D	I	P	D	A	.	.	.	.	D	I	.	R	L	Y	D	T	G	H	F	A	L	E	T	H	S	E	V	I	I
Query Conservation							.																														.	.	.	.			.
Alig confidence							.																														.	.	.	.			.
Template Conservation
Template Sequence		A	E	Y	F	R	N	V	D	Y	L	L	I	H	G	T	A	D	D	N	V	H	F	Q	N	S	A	Q	I	A	K	A	L	V	N	A	Q	V	D	F	Q	A	M	W	Y	S	D	Q	N	H	G	L	S	G	L	S	T	N	H	L	Y
Template Predicted Secondary structure
		302	.	.	.	.	.	.	.	310	.	.	.
Predicted Secondary structure
Query Sequence		P	T	I	R	Q	F	L	D	D	H	V	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		T	H	M	T	H	F	L	K	Q	C	F	S
Template Predicted Secondary structure

No model constructed - rank, confidence too low

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Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
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