Job Description Undefined Confidence 99.76% Date Thu Nov 13 08:26:15 GMT 2025 Rank 307 Aligned Residues 240 % Identity 14% Template c6k1tA_ PDB info PDB header: hydrolase Chain: A: PDB Molecule: Alpha/beta hydrolase fold family protein PDBTitle: the structure of francisella virulence factor bioj PDB Entry: PDBe RCSB PDBj Resolution UNK

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		26	.	.	.	30	.	.	.	.	.	.	.		.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.				.	.	.	.	.	.	.	70	.	.	.	.	.	.	.		.	.	80
Predicted Secondary structure														.																										.	.	.																.
Query Sequence		A	A	P	Q	V	H	Y	R	V	E	Q	V	.	G	D	V	K	V	F	Y	R	E	A	G	D	P	A	A	P	A	V	L	L	L	H	G	F	A	.	.	.	A	S	S	Y	M	W	R	D	V	I	E	A	L	A	D	.	G	Y	H
Query Conservation														.																										.	.	.																.
Alig confidence														.																										.	.	.																.
Template Conservation
Template Sequence		P	R	P	D	I	I	E	E	D	I	K	L	E	N	D	T	I	L	R	H	Y	K	P	K	K	A	S	D	K	A	V	L	F	I	H	G	G	G	W	C	L	S	S	I	D	T	Y	D	H	V	C	R	Y	L	C	D	Q	G	N	L
Template Known Secondary structure		.	.	.	S									T	T	S									S	S												S	T	T	T	S			G	G	G	G												T
Template Predicted Secondary structure
		81	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120			.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.
Predicted Secondary structure																																										.	.
Query Sequence		V	I	A	P	D	L	P	A	F	G	Y	T	E	A	P	A	R	G	Q	Y	D	Y	T	F	A	N	L	T	K	T	I	E	R	F	T	D	Q	L	K	L	.	.	T	R	Y	A	M	A	V	H	D	Y	G	A	P	V	G	W	R	L
Query Conservation																																										.	.
Alig confidence																	.	.																								.	.
Template Conservation																	.	.
Template Sequence		N	I	F	S	L	E	Y	G	L	G	P	E	D	K	Y	.	.	P	A	A	V	N	H	A	L	Y	A	Y	D	W	L	Y	E	N	I	T	K	F	N	L	S	T	E	N	I	F	V	M	G	D	S	A	G	G	N	L	V	T	I	I
Template Known Secondary structure											T	T	T	S		T	.	.	T																	G	G	G	G	T			G	G	G							T
Template Predicted Secondary structure																	.	.
		139	140	.	.	.	.	.		.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.
Predicted Secondary structure									.
Query Sequence		A	L	A	H	P	S	R	.	I	T	A	I	I	S	Q	N	G	N	A	Y	E	E	G	L	S	A	G	W	E	P	I	R	K	Y	W	N	D	P	T	A	E	N	R	Q	A	L	S	D	F	P	T	P	A	S	I	K	W	Q	Y	V
Query Conservation									.
Alig confidence									.												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		C	H	E	R	Q	E	N	M	P	K	A	Q	I	L	V	Y	P	A	V	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure						G	G	G			S						S				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
		198	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.
Predicted Secondary structure
Query Sequence		E	G	V	S	D	T	S	L	V	A	P	D	A	Y	T	L	E	G	A	Q	I	L	R	P	G	M	A	D	I	Q	L	D	L	L	L	D	Y	A	T	N	V	E	Q	Y	P	A	F	Q	A	Y	F	R	E	Y	Q	P	P	L	L	A
Query Conservation
Alig confidence		.	.	.
Template Conservation		.	.	.
Template Sequence		.	.	.	D	M	Y	T	K	Y	D	S	N	T	K	F	D	E	Y	K	Y	H	L	T	T	E	W	C	E	L	F	L	K	A	Y	I	G	P	K	K	L	R	Q	P	T	I	S	P	L	F	Y	K	D	T	N	Q	P	D	T	L	I
Template Known Secondary structure		.	.	.		S	S				T					T		S	G	G	G	S														T	S	S	G	G	G		S	T	T	T		G	G	G			S
Template Predicted Secondary structure		.	.	.
		258	.	260	.	.	.	.	.	.	.			.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.		.	.	.	.	.	290	.	.	.								.	.	.	.	.	.	300	.	.	.	.	.	.	.
Predicted Secondary structure												.	.																		.										.	.	.	.	.	.	.
Query Sequence		V	W	G	E	H	D	P	F	F	L	.	.	P	P	G	A	E	A	W	K	R	D	I	P	D	A	D	I	R	.	L	Y	D	T	G	H	F	A	L	.	.	.	.	.	.	.	E	T	H	S	E	V	I	I	P	T	I	R	Q	F
Query Conservation												.	.																		.										.	.	.	.	.	.	.
Alig confidence												.	.																		.										.	.	.	.	.	.	.
Template Conservation
Template Sequence		V	A	A	T	H	D	I	L	I	D	G	I	Y	A	Y	E	E	K	L	K	Q	Q	G	T	Y	V	E	T	H	Y	D	D	E	M	Y	H	G	F	I	G	G	L	G	V	V	P	F	E	N	P	K	I	A	L	D	K	I	I	E	F
Template Known Secondary structure							S	T	T														T	T													T	T	G	G	G	G	T	T	T	S	S		S
Template Predicted Secondary structure
		308	.	310	.
Predicted Secondary structure
Query Sequence		L	D	D	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		I	N	K	R
Template Known Secondary structure				T
Template Predicted Secondary structure

No model constructed - rank, confidence too low

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Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
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