Job Description Undefined Confidence 99.74% Date Thu Nov 13 08:26:15 GMT 2025 Rank 343 Aligned Residues 248 % Identity 13% Template c6aaeB_ PDB info PDB header: hydrolase Chain: B: PDB Molecule: Esterase PDBTitle: crystal structure of chloramphenicol-metabolizaing enzyme estdl136 PDB Entry: PDBe RCSB PDBj Resolution UNK

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		24	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.					.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.				.	.	.	.	.	.	.	70	.	.	.	.	.	.
Predicted Secondary structure																								.	.	.	.																		.	.	.
Query Sequence		A	S	A	A	P	Q	V	H	Y	R	V	E	Q	V	G	D	V	K	V	F	Y	R	.	.	.	.	E	A	G	D	P	A	A	P	A	V	L	L	L	H	G	F	A	.	.	.	A	S	S	Y	M	W	R	D	V	I	E	A	L	A
Query Conservation																								.	.	.	.																		.	.	.
Alig confidence																								.	.	.	.																		.	.	.
Template Conservation
Template Sequence		P	P	Q	V	A	R	V	E	N	I	A	I	S	L	D	G	R	D	L	D	A	R	L	Y	V	P	E	D	A	D	E	R	P	A	L	M	V	Y	Y	H	G	G	G	W	V	I	G	T	L	D	T	H	D	G	T	C	R	A	L	A
Template Predicted Secondary structure
		77			.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.						.	.	120	.	.	.	.	.	.	.	.	.
Predicted Secondary structure			.	.																																									.	.	.	.	.
Query Sequence		D	.	.	G	Y	H	V	I	A	P	D	L	P	A	F	G	Y	T	E	A	P	A	R	G	Q	Y	D	Y	T	F	A	N	L	T	K	T	I	E	R	F	T	D	Q	.	.	.	.	.	L	K	L	T	R	Y	A	M	A	V	H	D
Query Conservation			.	.																																									.	.	.	.	.
Alig confidence			.	.																			.	.	.	.	.	.																	.	.	.	.	.
Template Conservation																							.	.	.	.	.	.
Template Sequence		Q	K	S	G	C	A	V	L	S	I	A	Y	R	L	A	P	E	Y	R	Y	P	.	.	.	.	.	.	A	P	A	E	D	C	Y	D	A	L	V	W	A	K	Q	N	A	A	T	L	G	V	D	G	D	R	L	A	V	G	G	D	S
Template Predicted Secondary structure																							.	.	.	.	.	.
		130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.					.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.
Predicted Secondary structure																		.	.	.	.
Query Sequence		Y	G	A	P	V	G	W	R	L	A	L	A	H	P	S	R	.	.	.	.	I	T	A	I	I	S	Q	N	G	N	A	Y	E	E	G	L	S	A	G	W	E	P	I	R	K	Y	W	N	D	P	T	A	E	N	R	Q	A	L	S	D
Query Conservation																		.	.	.	.
Alig confidence																		.	.	.	.
Template Conservation
Template Sequence		A	G	G	N	L	A	A	A	V	A	I	M	A	R	D	R	N	G	P	A	L	R	H	Q	L	L	I	Y	P	V	T	D	N	D	F	T	L	A	S	Y	A	E	N	G	G	G	E	Y	Y	L	S	T	D	G	M	R	W	F	W	G
Template Predicted Secondary structure
		186	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.
Predicted Secondary structure
Query Sequence		F	P	T	P	A	S	I	K	W	Q	Y	V	E	G	V	S	D	T	S	L	V	A	P	D	A	Y	T	L	E	G	A	Q	I	L	R	P	G	M	A	D	I	Q	L	D	L	L	L	D	Y	A	T	N	V	E	Q	Y	P	A	F	Q
Query Conservation
Alig confidence												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		H	Y	L	G	D	T	A	A	E	N	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A	P	L	A	A	V	L	N	V
Template Predicted Secondary structure												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
		246	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.					.	.		.	.	.	.	.	.	290	.	.						.	.	.
Predicted Secondary structure																																						.	.	.	.			.										.	.	.	.	.
Query Sequence		A	Y	F	R	E	Y	Q	P	P	L	L	A	V	W	G	E	H	D	P	F	F	L	P	P	G	A	E	A	W	K	R	D	I	P	D	A	.	.	.	.	D	I	.	R	L	Y	D	T	G	H	F	A	.	.	.	.	.	L	E	T
Query Conservation																																						.	.	.	.			.										.	.	.	.	.
Alig confidence								.														.	.															.	.	.	.			.										.	.	.	.	.
Template Conservation								.														.	.
Template Sequence		A	D	L	S	G	L	.	A	P	A	T	V	I	T	A	E	Y	D	P	L	.	.	R	D	E	G	I	A	Y	A	K	K	L	D	A	A	G	V	P	V	D	A	A	T	A	P	G	M	I	H	G	F	F	S	M	F	E	A	V	P
Template Predicted Secondary structure								.														.	.
		296	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.
Predicted Secondary structure
Query Sequence		H	S	E	V	I	I	P	T	I	R	Q	F	L	D	D	H	V	S	L	H	R	Q	E	G	A	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	S	W	E	W	I	E	R	G	A	S	N	L	K	R	D	L	A	L	E	H	H	H	H	H	H
Template Predicted Secondary structure

No model constructed - rank, confidence too low

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Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
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