Job Description Undefined Confidence 99.71% Date Thu Nov 13 08:26:15 GMT 2025 Rank 304 Aligned Residues 241 % Identity 14% Template c5yp4A_ PDB info PDB header: hydrolase Chain: A: PDB Molecule: Dipeptidyl aminopeptidase 4 PDBTitle: crystal structure of dipeptidyl peptidase iv (dpp iv) with lys-pro from pseudoxanthomonas mexicana wo24 PDB Entry: PDBe RCSB PDBj Resolution UNK

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		16	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.							.	.	.	.	.	.	.	60	.	.	.	.	.	.
Predicted Secondary structure																																							.	.	.	.	.	.															.	.	.
Query Sequence		G	D	H	A	P	G	G	R	A	S	A	A	P	Q	V	H	Y	R	V	E	Q	V	G	D	V	K	V	F	Y	R	E	A	G	D	P	A	A	.	.	.	.	.	.	P	A	V	L	L	L	H	G	F	A	A	S	S	Y	.	.	.
Query Conservation																																							.	.	.	.	.	.															.	.	.
Alig confidence																																							.	.	.	.	.	.															.	.	.
Template Conservation
Template Sequence		H	P	Y	A	K	Y	R	A	A	H	Q	P	T	A	Y	G	T	L	T	A	A	D	G	T	T	P	L	H	Y	S	L	I	K	P	A	G	F	D	P	K	K	Q	Y	P	V	V	V	F	V	Y	G	G	P	A	A	Q	T	V	T	R
Template Known Secondary structure		S	T	T					T	T												T	T	S	S									.	.	T	T			T	T	S											S	T	T			S			S
Template Predicted Secondary structure
							67	.	.	70	.	.	.	.	.	.	.		.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.						.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.												.																					.	.	.	.	.
Query Sequence		.	.	.	.	.	M	W	R	D	V	I	E	A	L	A	D	.	G	Y	H	V	I	A	P	D	L	P	A	F	G	Y	T	E	A	P	A	R	.	.	.	.	.	G	Q	Y	D	Y	T	F	A	N	L	T	K	T	I	E	R	F	T
Query Conservation		.	.	.	.	.												.																					.	.	.	.	.
Alig confidence		.	.	.	.	.												.																					.	.	.	.	.
Template Conservation
Template Sequence		A	W	P	G	R	S	D	S	F	F	N	Q	Y	L	A	Q	Q	G	Y	V	V	F	T	L	D	N	R	G	T	P	R	R	G	A	A	F	G	G	A	L	Y	G	K	Q	G	T	V	E	V	D	D	Q	L	R	G	I	E	W	L	K
Template Known Secondary structure			.	.	.	T	T											T	T									T	T	S	S	S	S						G	G	G	T	T		T	T	T
Template Predicted Secondary structure
		116	.			.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.
Predicted Secondary structure				.	.
Query Sequence		D	Q	.	.	L	K	L	T	R	Y	A	M	A	V	H	D	Y	G	A	P	V	G	W	R	L	A	L	A	H	P	S	R	I	T	A	I	I	S	Q	N	G	N	A	Y	E	E	G	L	S	A	G	W	E	P	I	R	K	Y	W	N
Query Conservation				.	.
Alig confidence				.	.																																													.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																		.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		S	Q	A	F	V	D	P	A	R	I	G	V	Y	G	W	S	N	G	G	Y	M	T	L	M	L	L	A	K	H	D	E	A	Y	A	C	G	V	A	G	A	P	V	T	D	W	A	L	Y	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		T	S	T	T												T														T	T	T		S						S					G	G	G	S	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																		.	.	.	.	.	.	.	.	.	.	.	.
		174	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.
Predicted Secondary structure
Query Sequence		D	P	T	A	E	N	R	Q	A	L	S	D	F	P	T	P	A	S	I	K	W	Q	Y	V	E	G	V	S	D	T	S	L	V	A	P	D	A	Y	T	L	E	G	A	Q	I	L	R	P	G	M	A	D	I	Q	L	D	L	L	L	D
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	T	H	Y	T	E	R	Y	M	D	L	P	K	A
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	B											G	G	G
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
		234	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280					.	.	.	.		.	.	.	.
Predicted Secondary structure																																																	.	.	.	.					.
Query Sequence		Y	A	T	N	V	E	Q	Y	P	A	F	Q	A	Y	F	R	E	Y	Q	P	P	L	L	A	V	W	G	E	H	D	P	F	F	L	P	P	G	A	E	A	W	K	R	D	I	P	D	.	.	.	.	A	D	I	R	.	L	Y	D	T
Query Conservation																																																	.	.	.	.					.
Alig confidence																																																	.	.	.	.					.
Template Conservation
Template Sequence		N	E	A	G	Y	R	E	A	S	V	F	T	H	V	D	G	I	G	A	G	K	L	L	L	I	H	G	M	A	D	D	N	V	L	F	T	N	S	T	K	L	M	S	E	L	Q	K	R	G	T	P	F	E	L	M	T	Y	P	G	A
Template Known Secondary structure															G	G	G	S	.	T	T	T							T	T		T	T	T	T	T														T									T	T
Template Predicted Secondary structure
		289	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.
Predicted Secondary structure
Query Sequence		G	H	F	A	L	E	T	H	S	E	V	I	I	P	T	I	R	Q	F	L	D	D	H	V	S	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	H	G	L	R	G	S	D	L	L	H	R	Y	R	L	T	E	D	F	F	A	R	C	L	K	P
Template Known Secondary structure			S	S
Template Predicted Secondary structure

No model constructed - rank, confidence too low

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Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
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