Job Description Undefined Confidence 99.96% Date Thu Nov 13 08:26:15 GMT 2025 Rank 11 Aligned Residues 280 % Identity 22% Template c5y6yA_ PDB info PDB header: hydrolase Chain: A: PDB Molecule: Epoxide hydrolase PDBTitle: the crystal structure of vreh2 mutant m263n PDB Entry: PDBe RCSB PDBj Resolution UNK Model Dimensions (Å) X:48.140 Y:50.821 Z:50.332

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

29

30

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40

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50

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60

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70

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80

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Predicted Secondary structure

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Query Sequence

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Query Conservation

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Alig confidence

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Template Conservation

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Template Sequence

E

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E

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R

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V

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Template Known Secondary structure

T

T

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S

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T

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G

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G

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T

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Template Predicted Secondary structure

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88

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100

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110

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120

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130

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140

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Predicted Secondary structure

Query Sequence

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Query Conservation

Alig confidence

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Template Conservation

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Template Sequence

G

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Template Known Secondary structure

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Template Predicted Secondary structure

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190

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Predicted Secondary structure

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Query Sequence

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N

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Query Conservation

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Alig confidence

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Template Conservation

Template Sequence

A

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N

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T

Template Known Secondary structure

S

T

T

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B

T

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T

Template Predicted Secondary structure

199

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210

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230

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240

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Predicted Secondary structure

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Query Sequence

G

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N

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Query Conservation

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Alig confidence

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Template Conservation

Template Sequence

R

K

P

G

P

P

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Y

G

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T

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F

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G

P

L

N

Y

Y

R

N

M

N

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N

W

Template Known Secondary structure

S

B

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T

T

S

T

T

T

T

T

T

S

S

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T

T

S

S

T

T

Template Predicted Secondary structure

249

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260

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270

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280

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290

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Predicted Secondary structure

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Query Sequence

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Query Conservation

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Alig confidence

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Template Conservation

Template Sequence

E

L

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Q

D

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P

N

L

E

E

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Q

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N

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F

N

Template Known Secondary structure

T

G

G

G

T

T

S

T

T

T

T

T

T

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T

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B

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Template Predicted Secondary structure

293

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300

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310

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Predicted Secondary structure

Query Sequence

L

E

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H

S

E

V

I

I

P

T

I

R

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F

L

D

D

H

Query Conservation

Alig confidence

Template Conservation

Template Sequence

N

Q

E

A

A

E

E

I

N

N

H

I

Y

D

F

I

K

K

F

Template Known Secondary structure

T

T

Template Predicted Secondary structure

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Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
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